TY - GEN T1 - Intelligence Reform and Terrorism Prevention Act of 2004: "Lone Wolf" Amendment to the Foreign Intelligence Surveillance Act AN - 1679112690; SU00201 AB - Describes new "lone wolf" provision of Foreign Intelligence Surveillance Act when applied to "agent of a foreign power" and its impact on procedures for seeking FISA warrants. AU - United States. Library of Congress. Congressional Research Service. American Law Division AD - United States. Library of Congress. Congressional Research Service. American Law Division PY - 2004 SP - 6 KW - Americans KW - Executive Order 12333 (1981) KW - Foreign Intelligence Surveillance Act (1978) KW - Intelligence Reform and Terrorism Prevention Act (2004) KW - Noncitizens KW - Pen registers KW - Searches and seizures KW - Terrorism KW - United States Constitution. First Amendment KW - Warrants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679112690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_su&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Intelligence+Reform+and+Terrorism+Prevention+Act+of+2004%3A+%22Lone+Wolf%22+Amendment+to+the+Foreign+Intelligence+Surveillance+Act&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service.+American+Law+Division&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service.+American+Law+Division&rft.aufirst=&rft.date=2004-12-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ L2 - http://www.fas.org. LA - English DB - Digital National Security Archive N1 - Name - United States. Federal Bureau of Investigation; United States. Foreign Intelligence Surveillance Court N1 - Publication note - National Security Archive. Wiretap Debate Déjà Vu. Electronic Briefing Book 178, February 4, 2006, http://www2.gwu.edu/~nsarchiv/NSAEBB/NSAEBB178/ (previously published document) N1 - Analyte descriptor - NSA document type: Report ; Location of original: Available [Online]: Federation of American Scientists N1 - Last updated - 2015-12-14 ER - TY - JOUR T1 - Splicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay. AN - 67204005; 15608055 AB - Metazoan cells have two pathways for intron removal involving the U2- and U12-type spliceosomes, which contain mostly nonoverlapping sets of small nuclear ribonucleoproteins. We show that in vitro splicing of a U12-type intron assembles an exon junction complex (EJC) that is comparably positioned and contains many of the same components as that deposited by the U2-type spliceosome. The presence of a U12-type intron downstream of a premature termination codon within an open reading frame (ORF) induces nonsense-mediated decay of the mRNA in vivo. These findings suggest a common pathway for EJC assembly by the two spliceosomes and highlight the evolutionary age of the EJC and its downstream functions in gene expression. JF - Proceedings of the National Academy of Sciences of the United States of America AU - Hirose, Tetsuro AU - Shu, Mei-Di AU - Steitz, Joan A AD - Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. Y1 - 2004/12/28/ PY - 2004 DA - 2004 Dec 28 SP - 17976 EP - 17981 VL - 101 IS - 52 SN - 0027-8424, 0027-8424 KW - Codon, Nonsense KW - 0 KW - DNA, Complementary KW - RNA Precursors KW - RNA, Messenger KW - RNA, Small Nuclear KW - Ribonucleoproteins, Small Nuclear KW - U12 small nuclear RNA KW - RNA KW - 63231-63-0 KW - Ribonuclease H KW - EC 3.1.26.4 KW - Index Medicus KW - Ribonuclease H -- chemistry KW - RNA Precursors -- metabolism KW - Plasmids -- metabolism KW - Cell Nucleus -- metabolism KW - Exons KW - HeLa Cells KW - Humans KW - Open Reading Frames KW - Immunoprecipitation KW - Ribonucleoproteins, Small Nuclear -- metabolism KW - Evolution, Molecular KW - Mutagenesis, Site-Directed KW - Transfection KW - Spliceosomes -- metabolism KW - RNA -- metabolism KW - DNA, Complementary -- metabolism KW - RNA -- chemistry KW - Gene Expression Regulation KW - Time Factors KW - Cell Line KW - RNA, Messenger -- metabolism KW - RNA, Small Nuclear -- metabolism KW - RNA Splicing KW - Introns KW - RNA, Small Nuclear -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67204005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Splicing+of+U12-type+introns+deposits+an+exon+junction+complex+competent+to+induce+nonsense-mediated+mRNA+decay.&rft.au=Hirose%2C+Tetsuro%3BShu%2C+Mei-Di%3BSteitz%2C+Joan+A&rft.aulast=Hirose&rft.aufirst=Tetsuro&rft.date=2004-12-28&rft.volume=101&rft.issue=52&rft.spage=17976&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.issn=00278424&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-02-28 N1 - Date created - 2004-12-29 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: EMBO J. 2002 Jul 1;21(13):3536-45 [12093754] Nature. 2002 May 16;417(6886):304-8 [11979277] Curr Biol. 2002 Jul 9;12(13):1060-7 [12121612] Genes Dev. 2002 Nov 1;16(21):2778-91 [12414731] J Cell Biol. 2002 Nov 25;159(4):579-88 [12438415] Science. 2002 Dec 13;298(5601):2205-8 [12411573] Mol Cell. 2003 Mar;11(3):837-43 [12667464] EMBO J. 2003 May 15;22(10):2472-83 [12743041] Mol Cell. 2003 Jul;12(1):113-23 [12887897] Mol Cell Biol. 2003 Oct;23(20):7363-76 [14517304] Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11327-32 [12972633] Nat Rev Mol Cell Biol. 2003 Dec;4(12):960-70 [14685174] RNA. 2004 Feb;10(2):200-9 [14730019] Genes Dev. 2004 Jan 15;18(2):210-22 [14752011] J Biol Chem. 2004 Feb 20;279(8):7009-13 [14625303] Nature. 2004 Feb 19;427(6976):753-7 [14973490] Nat Rev Mol Cell Biol. 2004 Feb;5(2):89-99 [15040442] Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4118-23 [15024115] Nat Struct Mol Biol. 2004 Apr;11(4):346-51 [15034551] RNA. 2004 Jun;10(6):929-41 [15146077] Nucleic Acids Res. 1983 Mar 11;11(5):1475-89 [6828386] J Biol Chem. 1990 Nov 15;265(32):19624-31 [2246248] Cell. 1996 Mar 8;84(5):801-11 [8625417] Trends Biochem Sci. 1997 Apr;22(4):132-7 [9149533] Genes Dev. 1997 Jul 15;11(14):1864-72 [9242493] RNA. 1998 Jul;4(7):801-15 [9671053] Mol Cell. 1998 Dec;2(6):773-85 [9885565] Mol Cell Biol. 1999 Mar;19(3):1705-19 [10022858] Genes Dev. 1999 Apr 1;13(7):851-63 [10197985] Science. 1999 Jun 18;284(5422):2003-5 [10373121] RNA. 1999 Jul;5(7):893-908 [10411133] Genes Dev. 2000 May 1;14(9):1098-108 [10809668] Nature. 2000 Sep 21;407(6802):401-5 [11014198] EMBO J. 2000 Dec 15;19(24):6860-9 [11118221] Cell. 2000 Dec 22;103(7):1121-31 [11163187] Mol Cell. 2001 Jan;7(1):217-26 [11172726] EMBO J. 2001 Aug 15;20(16):4536-46 [11500380] EMBO J. 2001 Sep 3;20(17):4987-97 [11532962] Nat Cell Biol. 2001 Sep;3(9):E201-4 [11533670] Science. 2001 Sep 7;293(5536):1832-6 [11546873] Science. 2001 Sep 7;293(5536):1836-9 [11546874] Nature. 2001 Oct 11;413(6856):644-7 [11675789] EMBO J. 2001 Nov 15;20(22):6424-33 [11707413] Mol Cell Biol. 2002 May;22(10):3219-29 [11971955] EMBO J. 2002 Jul 15;21(14):3804-15 [12110592] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Be The First CIO Of The U.S. Senate AN - 205940862 JF - CIO AU - J. Greg Hanson Assistant sergeant at arms and CIO for the U.S. Senate. Y1 - 2004/12/15/ PY - 2004 DA - 2004 Dec 15 SP - 1 CY - Framingham PB - CXO Media, Inc. VL - 18 IS - 6 SN - 08949301 KW - Business And Economics--Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/205940862?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabiglobal&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=CIO&rft.atitle=Be+The+First+CIO+Of+The+U.S.+Senate&rft.au=J.+Greg+Hanson+Assistant+sergeant+at+arms+and+CIO+for+the+U.S.+Senate.&rft.aulast=J.+Greg+Hanson+Assistant+sergeant+at+arms+and+CIO+for+the+U.S.+Senate.&rft.aufirst=&rft.date=2004-12-15&rft.volume=18&rft.issue=6&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=CIO&rft.issn=08949301&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright 2004 CXO Media Inc N1 - Last updated - 2014-05-22 ER - TY - JOUR T1 - Water Infrastructure Project Earmarks in EPA Appropriations: Trends and Policy Implications AN - 14737552; 10675644 AB - Earmarks in appropriations legislation are funds set aside within an account for specified projects or locations. These have been increasing in recent years as a way to help designated communities meet needs to build and upgrade water infrastructure systems, whose estimated future funding needs exceed $300 billion. Of the $40.8 billion appropriated to EPA for water infrastructure assistance under the Clean Water Act and the Safe Drinking Water Act since 1989, 16% has gone to earmarked project grants. The trend of appropriators to earmark smaller awards is reflected in the fact that only 62 of 520 in FY2004 and 76 in FY2005 received amounts of $1 million or more. JF - US Congressional Research Service Report RL32201 AU - Copeland, Claudia Y1 - 2004/12/15/ PY - 2004 DA - 2004 Dec 15 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - EPA, FEDERAL KW - CLEAN WATER ACT KW - WATER RESOURCES DEVELOPMENT KW - URBAN WATER RESOURCES KW - WATER RESOURCES FINANCING KW - SAFE DRINKING WATER ACT 74 KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14737552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+RL32201&rft.atitle=Water+Infrastructure+Project+Earmarks+in+EPA+Appropriations%3A+Trends+and+Policy+Implications&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-12-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+RL32201&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - URBAN WATER RESOURCES; WATER RESOURCES FINANCING; EPA, FEDERAL; SAFE DRINKING WATER ACT 74; CLEAN WATER ACT; WATER RESOURCES DEVELOPMENT ER - TY - JOUR T1 - Safe Drinking Water Act: Implementation and Issues AN - 14737122; 10675645 AB - Key drinking water issues in the 108th Congress involved water infrastructure funding and problems posed by methyl tert butyl ether (MTBE), lead, and other specific water pollutants. Both chambers passed bills to address MTBE contamination, and Congress required health studies of perchlorate and directed DOD and EPA to research perchlorate groundwater pollution in the southwest. For FY2005, Congress approved about $850 million for the drinking water state revolving fund program. Bills were also submitted to increase funding for water infrastructure projects, with emphasis on assisting small systems. JF - US Congressional Research Service Report IB10118 AU - Tiemann, Mary Y1 - 2004/12/08/ PY - 2004 DA - 2004 Dec 08 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - FUEL ADDITIVES KW - GROUNDWATER KW - STATE AND LOCAL ENV PROGRAMS KW - WATER RESOURCES FINANCING KW - SAFE DRINKING WATER ACT 74 KW - WATER QUALITY STANDARDS KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14737122?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10118&rft.atitle=Safe+Drinking+Water+Act%3A+Implementation+and+Issues&rft.au=Tiemann%2C+Mary&rft.aulast=Tiemann&rft.aufirst=Mary&rft.date=2004-12-08&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10118&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - STATE AND LOCAL ENV PROGRAMS; WATER RESOURCES FINANCING; SAFE DRINKING WATER ACT 74; LEAD; WATER QUALITY STANDARDS; GROUNDWATER; FUEL ADDITIVES ER - TY - JOUR T1 - Clean Water Act Issues in the 108th Congress AN - 14737324; 10675642 AB - Reauthorization of the wastewater infrastructure funding program of the Clean Water Act was considered by the 108th Congress. In October 2004, the Senate Environment and Public Works Committee reported legislation to authorize $20 billion in funding for clean water infrastructure. Other issues have received limited congressional attention, including whether and how the administration will revise the current program for restoration of pollution-impaired waters. Regulatory protection of wetlands, stormwater rules for the oil and gas industry, and animal waste management issues are also discussed. JF - US Congressional Research Service Report IB10108 AU - Copeland, Claudia Y1 - 2004/12/06/ PY - 2004 DA - 2004 Dec 06 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - LEGISLATION, FEDERAL KW - LIVESTOCK FEEDLOT RUNOFF KW - CLEAN WATER ACT KW - STORM RUNOFF KW - WATER POLLUTION CONTROL FINANCING KW - ENV RESTORATION KW - WATER QUALITY STANDARDS KW - WETLANDS KW - WATER QUALITY PROGRAMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14737324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10108&rft.atitle=Clean+Water+Act+Issues+in+the+108th+Congress&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-12-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10108&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - WATER POLLUTION CONTROL FINANCING; ENV RESTORATION; LEGISLATION, FEDERAL; LIVESTOCK FEEDLOT RUNOFF; CLEAN WATER ACT; STORM RUNOFF; WATER QUALITY STANDARDS; WETLANDS; WATER QUALITY PROGRAMS ER - TY - JOUR T1 - Carbon dioxide concentrations in the atmosphere of underground environments as tracers of climatic changes AN - 51230090; 2008-077543 JF - Eos, Transactions, American Geophysical Union AU - Madonia, P AU - Di Pietro, R AU - Francofonte, V AU - Anonymous Y1 - 2004/12// PY - 2004 DA - December 2004 SP - Abstract B33A EP - 0238 PB - American Geophysical Union, Washington, DC VL - 85 IS - 47, Suppl. SN - 0096-3941, 0096-3941 KW - concentration KW - terrestrial environment KW - monitoring KW - caves KW - Carburangeli Cave KW - atmosphere KW - Europe KW - Palermo Italy KW - Italy KW - climate change KW - cave environment KW - Southern Europe KW - carbon dioxide KW - Sicily Italy KW - Santa Ninfa Cave KW - tracers KW - ecology KW - depositional environment KW - solution features KW - 23:Geomorphology KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51230090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Eos%2C+Transactions%2C+American+Geophysical+Union&rft.atitle=Carbon+dioxide+concentrations+in+the+atmosphere+of+underground+environments+as+tracers+of+climatic+changes&rft.au=Madonia%2C+P%3BDi+Pietro%2C+R%3BFrancofonte%2C+V%3BAnonymous&rft.aulast=Madonia&rft.aufirst=P&rft.date=2004-12-01&rft.volume=85&rft.issue=47%2C+Suppl.&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Eos%2C+Transactions%2C+American+Geophysical+Union&rft.issn=00963941&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - American Geophysical Union 2004 fall meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - DC N1 - Last updated - 2012-06-07 N1 - CODEN - EOSTAJ N1 - SubjectsTermNotLitGenreText - atmosphere; carbon dioxide; Carburangeli Cave; cave environment; caves; climate change; concentration; depositional environment; ecology; Europe; Italy; monitoring; Palermo Italy; Santa Ninfa Cave; Sicily Italy; solution features; Southern Europe; terrestrial environment; tracers ER - TY - JOUR T1 - Correspondence: conflicts of interests: declarations for all. AN - 21425078; 12421263 AB - Concerning your editorial, "Embracing Scrutiny," in the October issue of EHP [Environ Health Perspect 112:A788 (2004)], the need for full disclosure of all potential conflicts of interest by all coauthors contributing to a publication in EHP is commendable and obviously needed. Might I take this one step further and suggest that all reviewers of EHP manuscripts be required to sign a form listing all of their potential conflicts of interest. JF - Environmental Health Perspectives AU - DW, Nebert Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A980 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - conflict of interests KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21425078?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+conflicts+of+interests%3A+declarations+for+all.&rft.au=DW%2C+Nebert&rft.aulast=DW&rft.aufirst=Nebert&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A980&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - conflict of interests ER - TY - JOUR T1 - The Relationship of Urinary Metabolites of Carbaryl/Naphthalene and Chlorpyrifos with Human Semen Quality AN - 21425004; 12425448 AB - Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure and decreased semen quality. In the present study we explored whether environmental exposures to 1-naphthol (1N), a metabolite of carbaryl and naphthalene, and 3,5,6-trichloro-2-pyridinol (TCPY), a metabolite of chlorpyrifos and chlorpyrifos-methyl, are associated with decreased semen quality in humans. Subjects (n=272) were recruited through a Massachusetts infertility clinic. Individual exposures were measured as spot urinary concentrations of 1N and TCPY adjusted using specific gravity. Semen quality was assessed as sperm concentration, percent motile sperm, and percent sperm with normal morphology, along with sperm motion parameters (straight-line velocity, curvilinear velocity, and linearity). Median TCPY and 1N concentrations were 3.22 and 3.19microg/L, respectively. For increasing 1N tertiles, adjusted odds ratios (ORs) were significantly elevated for below-reference sperm concentration (OR for low, medium, and high tertiles = 1.0, 4.2, 4.2, respectively; p-value for trend =0.01) and percent motile sperm (1.0, 2.5, 2.4; p-value for trend = 0.01). The sperm motion parameter most strongly associated with 1N was straight-line velocity. There were suggestive, borderline-significant associations for TCPY with sperm concentration and motility, whereas sperm morphology was weakly and nonsignificantly associated with both TCPY and 1N. The observed associations between altered semen quality and 1N are consistent with previous studies of carbaryl exposure, although suggestive associations with TCPY are difficult to interpret because human and animal data are currently limited. JF - Environmental Health Perspectives AU - Meeker, John D AU - Ryan, Louise AU - Barr, Dana B AU - Herrick, Robert F Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1665 EP - 1670 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Chlorpyrifos KW - USA, Massachusetts KW - Insecticides KW - Urine KW - Pesticides KW - Morphology KW - Carbaryl KW - Velocity KW - Naphthalene KW - Metabolites KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21425004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+of+Urinary+Metabolites+of+Carbaryl%2FNaphthalene+and+Chlorpyrifos+with+Human+Semen+Quality&rft.au=Meeker%2C+John+D%3BRyan%2C+Louise%3BBarr%2C+Dana+B%3BHerrick%2C+Robert+F&rft.aulast=Meeker&rft.aufirst=John&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1665&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Chlorpyrifos; Insecticides; Urine; Morphology; Pesticides; Naphthalene; Velocity; Carbaryl; Metabolites; USA, Massachusetts ER - TY - JOUR T1 - Is Bone Mineral Composition Disrupted by Organochlorines in East Greenland Polar Bears (Ursus maritimus)? AN - 21424957; 12425444 AB - We analyzed bone mineral density (BMD) in skulls of polar bears (Ursus maritimus) (n = 139) from East Greenland sampled during 1892-2002. Our primary goal was to detect possible changes in bone mineral content (osteopenia) due to elevated exposure to organochlorine [polychlorinated biphenyls (PCBs), dichlorodiphenyl trichloroethane (DDT) and its metabolites, chlordanes (CHLs), dieldrin, hexacyclohexanes, hexachlorobenzene] and polybrominated diphenyl ether (PBDE) compounds. To ensure that the BMD value in skull represented the mineral status of the skeletal system in general, we compared BMD values in femur and three lumbar vertebrae with skull in a subsample. We detected highly significant correlations between BMD in skull and femur (r = 0.99; p 0.001; n = 13) and skull and vertebrae (r = 0.97; p 0.001; n = 8). BMD in skulls sampled in the supposed pre-organochlorine/PBDE period (1892-1932) was significantly higher than that in skulls sampled in the supposed pollution period (1966-2002) for subadult females, subadult males, and adult males (all, p 0.05) but not adult females (p = 0.94). We found a negative correlation between organochlorines and skull BMD for the sum of PCBs (SigmaPCB; p 0.04) and SigmaCHL (p 0.03) in subadults and for dieldrin (p 0.002) and SigmaDDT (p 0.02) in adult males; indications for SigmaPBDE in subadults were also found (p = 0.06). In conclusion, the strong correlative relationships suggest that disruption of the bone mineral composition in East Greenland polar bears may have been caused by organochlorine exposure. JF - Environmental Health Perspectives AU - Sonne, Christian AU - Dietz, Rune AU - Born, Erik W AU - Riget, Frank F Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1711 EP - 1716 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - PBDE KW - Organochlorine compounds KW - Bones KW - Chlorine compounds KW - Dieldrin KW - Greenland, Oestgroenland KW - Vertebrae KW - polybrominated diphenyl ethers KW - Insecticides KW - mineral composition KW - Skull KW - bears KW - DDT KW - Ursus maritimus KW - Mineral composition KW - bone mineral density KW - Minerals KW - PCB compounds KW - PCB KW - Q5 08502:Methods and instruments KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21424957?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Is+Bone+Mineral+Composition+Disrupted+by+Organochlorines+in+East+Greenland+Polar+Bears+%28Ursus+maritimus%29%3F&rft.au=Sonne%2C+Christian%3BDietz%2C+Rune%3BBorn%2C+Erik+W%3BRiget%2C+Frank+F&rft.aulast=Sonne&rft.aufirst=Christian&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1711&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - PBDE; Bones; Skull; Chlorine compounds; DDT; Dieldrin; Mineral composition; Vertebrae; PCB; polybrominated diphenyl ethers; mineral composition; Insecticides; Organochlorine compounds; bears; PCB compounds; Minerals; bone mineral density; Ursus maritimus; Greenland, Oestgroenland ER - TY - JOUR T1 - Epidemiologic Evaluation of Measurement Data in the Presence of Detection Limits AN - 21424273; 12425433 AB - Quantitative measurements of environmental factors greatly improve the quality of epidemiologic studies but can pose challenges because of the presence of upper or lower detection limits or interfering compounds, which do not allow for precise measured values. We consider the regression of an environmental measurement (dependent variable) on several covariates (independent variables). Various strategies are commonly employed to impute values for interval-measured data, including assignment of one-half the detection limit to nondetected values or of "fill-in" values randomly selected from an appropriate distribution. On the basis of a limited simulation study, we found that the former approach can be biased unless the percentage of measurements below detection limits is small (5-10%). The fill-in approach generally produces unbiased parameter estimates but may produce biased variance estimates and thereby distort inference when 30% or more of the data are below detection limits. Truncated data methods (e.g., Tobit regression) and multiple imputation offer two unbiased approaches for analyzing measurement data with detection limits. If interest resides solely on regression parameters, then Tobit regression can be used. If individualized values for measurements below detection limits are needed for additional analysis, such as relative risk regression or graphical display, then multiple imputation produces unbiased estimates and nominal confidence intervals unless the proportion of missing data is extreme. We illustrate various approaches using measurements of pesticide residues in carpet dust in control subjects from a case-control study of non-Hodgkin lymphoma. JF - Environmental Health Perspectives AU - Lubin, Jay H AU - Colt, Joanne S AU - Camann, David AU - Davis, Scott Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1691 EP - 1696 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - non-Hodgkin's lymphoma KW - environmental factors KW - Pesticide residues KW - Simulation KW - Dust KW - ENA 09:Land Use & Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21424273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Epidemiologic+Evaluation+of+Measurement+Data+in+the+Presence+of+Detection+Limits&rft.au=Lubin%2C+Jay+H%3BColt%2C+Joanne+S%3BCamann%2C+David%3BDavis%2C+Scott&rft.aulast=Lubin&rft.aufirst=Jay&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1691&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - non-Hodgkin's lymphoma; environmental factors; Pesticide residues; Simulation; Dust ER - TY - JOUR T1 - Is Environmental Health a Basic Human Right? AN - 21423506; 12425439 AB - Who truly owns natural resources such as the water, the air, and the forests? In some areas, courts are ruling that such resources are the property of the people, while others areas bow to free market forces. As the world's population grows greater, resources grow scarcer, and the link between civil instability and environmental degradation becomes clearer, deciding who owns our planet will become less a theoretical exercise to be pondered at leisure than a determination that is deferred at the peril of our survival. JF - Environmental Health Perspectives AU - Taylor, David A Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A1006 EP - A1009 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Environmental degradation KW - world population KW - Human rights KW - Natural resources KW - courts KW - Forests KW - Environmental health KW - survival KW - ENA 13:Population Planning & Control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423506?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Is+Environmental+Health+a+Basic+Human+Right%3F&rft.au=Taylor%2C+David+A&rft.aulast=Taylor&rft.aufirst=David&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A1006&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Environmental degradation; world population; Human rights; courts; Natural resources; Environmental health; Forests; survival ER - TY - JOUR T1 - Battle Scars: Global Conflicts and Environmental Health AN - 21423466; 12425438 AB - The nature and weapons of war have changed radically in the last century, bringing conflict off the battleground and into city streets, and thereby magnifying its environmental health consequences. Age-old problems still follow war---lack of food, shelter, water, and sanitation, risk of infectious disease, and psychological trauma. But modern war also saddles populations with new threats from industrial and military chemicals, pesticides, and radiation, and humanitarian aid systems designed to help people after natural disasters cannot function properly in combat environments. A few encouraging strides are being made, such as the overall reduction in landmine production and use. It remains to be seen what further progress can be made in alleviating the environmental health disaster that is war. JF - Environmental Health Perspectives AU - Brown, Valerie J Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A994 EP - 1003 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - conflicts KW - Chemicals KW - Weapons KW - landmines KW - natural disasters KW - Pesticides KW - Environmental health KW - Military KW - war KW - ENA 09:Land Use & Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Battle+Scars%3A+Global+Conflicts+and+Environmental+Health&rft.au=Brown%2C+Valerie+J&rft.aulast=Brown&rft.aufirst=Valerie&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A994&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Chemicals; conflicts; Weapons; natural disasters; landmines; Pesticides; Environmental health; Military; war ER - TY - JOUR T1 - Effects of Loud Noise Exposure on DNA Integrity in Rat Adrenal Gland AN - 21418243; 12425435 AB - Loud noise is generally considered an environmental stressor causing negative effects on acoustic, cardiovascular, nervous, and endocrine systems. In this study, we investigated the effects of noise exposure on DNA integrity in rat adrenal gland evaluated by the comet assay. The exposure to loud noise (100 dBA) for 12 hr caused a significant increase of DNA damage in the adrenal gland. Genetic alterations did not decrease 24 hr after the cessation of the stimulus. We hypothesize that an imbalance of redox cell status is responsible for the induction and persistence of noise-induced cellular damage. JF - Environmental Health Perspectives AU - Frenzilli, Giada AU - Lenzi, Paola AU - Scarcelli, Vittoria AU - Fornai, Francesco Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1671 EP - 1672 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - environmental stress KW - Acoustics KW - Noise levels KW - DNA KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21418243?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+Loud+Noise+Exposure+on+DNA+Integrity+in+Rat+Adrenal+Gland&rft.au=Frenzilli%2C+Giada%3BLenzi%2C+Paola%3BScarcelli%2C+Vittoria%3BFornai%2C+Francesco&rft.aulast=Frenzilli&rft.aufirst=Giada&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1671&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Acoustics; environmental stress; DNA; Noise levels ER - TY - JOUR T1 - Long-Term Exposure to Environmental Concentrations of the Pharmaceutical Ethynylestradiol Causes Reproductive Failure in Fish AN - 21407686; 12425443 AB - Heightened concern over endocrine-disrupting chemicals is driven by the hypothesis that they could reduce reproductive success and affect wildlife populations, but there is little evidence for this expectation. The pharmaceutical ethynylestradiol (EE2) is a potent endocrine modulator and is present in the aquatic environment at biologically active concentrations. To investigate impacts on reproductive success and mechanisms of disruption, we exposed breeding populations (n = 12) of zebrafish (Danio rerio) over multiple generations to environmentally relevant concentrations of EE2. Life-long exposure to 5 ng/L EE2 in the F1 generation caused a 56% reduction in fecundity and complete population failure with no fertilization. Conversely, the same level of exposure for up to 40 days in mature adults in the parental F0 generation had no impact on reproductive success. Infertility in the F1 generation after life-long exposure to 5 ng/L EE2 was due to disturbed sexual differentiation, with males having no functional testes and either undifferentiated or intersex gonads. These F1 males also showed a reduced vitellogenic response when compared with F0 males, indicating an acclimation to EE2 exposure. Depuration studies found only a partial recovery in reproductive capacity after 5 months. Significantly, even though the F1 males lacked functional testes, they showed male-pattern reproductive behavior, inducing the spawning act and competing with healthy males to disrupt fertilization. Endocrine disruption is therefore likely to affect breeding dynamics and reproductive success in group-spawning fish. Our findings raise major concerns about the population-level impacts for wildlife of long-term exposure to low concentrations of estrogenic endocrine disruptors. JF - Environmental Health Perspectives AU - Nash, Jon P AU - Kime, David E AU - Van der Ven, Leo T M AU - Wester, Piet W Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1725 EP - 1733 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - Chemicals KW - Testes KW - endocrine disruptors KW - Animal reproductive organs KW - Wildlife KW - Spawning KW - Freshwater KW - Freshwater fish KW - Sex hormones KW - fecundity KW - Danio rerio KW - fertilization KW - breeding KW - Fish physiology KW - Endocrinology KW - Reproduction KW - Fish KW - Drugs KW - estrogens KW - Breeding success KW - Q5 08504:Effects on organisms KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21407686?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Long-Term+Exposure+to+Environmental+Concentrations+of+the+Pharmaceutical+Ethynylestradiol+Causes+Reproductive+Failure+in+Fish&rft.au=Nash%2C+Jon+P%3BKime%2C+David+E%3BVan+der+Ven%2C+Leo+T+M%3BWester%2C+Piet+W&rft.aulast=Nash&rft.aufirst=Jon&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1725&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Testes; Fish physiology; Animal reproductive organs; Endocrinology; Spawning; Freshwater fish; Drugs; Sex hormones; Breeding success; Chemicals; fecundity; fertilization; breeding; endocrine disruptors; Wildlife; Fish; Reproduction; estrogens; Danio rerio; Freshwater ER - TY - JOUR T1 - Forum. AN - 21407078; 12421262 AB - Short articles on the following topics: NRDC Knocks Nukes; NAFTA Worries in Juarez; Flu, Fetuses, and Schizophrenia; A Better Model for PD; EHPnet: POV's Borders: Environment; The Beat. JF - Environmental Health Perspectives AU - R, Chepesiuk AU - R, Dahl AU - J, Wakefield AU - H, Heimer AU - EE, Dooley Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A984 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - mental disorders KW - Fetuses KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21407078?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Forum.&rft.au=R%2C+Chepesiuk%3BR%2C+Dahl%3BJ%2C+Wakefield%3BH%2C+Heimer%3BEE%2C+Dooley&rft.aulast=R&rft.aufirst=Chepesiuk&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A984&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - mental disorders; Fetuses ER - TY - JOUR T1 - Prospective Study of Blood and Tibia Lead in Women Undergoing Surgical Menopause AN - 21400429; 12425449 AB - Despite the dramatic decline in environmental lead exposure in the United States during the past couple of decades, concern has been expressed regarding mobilization during menopause of existing lead stored in bone. To investigate whether bone lead concentrations decrease and blood lead levels increase, we conducted a prospective study of 91 women who were scheduled to undergo a bilateral oophorectomy for a benign condition at Mount Sinai Hospital in New York City during October 1994 through April 1999. We excluded women who were younger than 30 years of age or who were postmenopausal at the time of the surgery. We observed a small but significant increase in median blood lead levels between the baseline visit and the 6-month visit (0.4 microg/dL, p0.0001), particularly for women who were not on estrogen replacement therapy (0.7 microg/dL, p=0.008). No significant change was observed in blood lead values between 6 and 18 months postsurgery, nor was there evidence of significant changes in tibia lead concentrations during the follow-up period. These findings do not point to substantial mobilization of lead from cortical bone during menopause. JF - Environmental Health Perspectives AU - Berkowitz, Gertrud S AU - Wolff, Mary S AU - Lapinski, Robert H AU - Todd, Andrew C Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1673 EP - 1678 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Bone KW - Egypt, Arab Rep., Sinai Peninsula KW - USA, New York, New York City KW - post-menopause KW - menopause KW - estrogen replacement therapy KW - Females KW - Lead KW - surgery KW - Blood levels KW - Hospitals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21400429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prospective+Study+of+Blood+and+Tibia+Lead+in+Women+Undergoing+Surgical+Menopause&rft.au=Berkowitz%2C+Gertrud+S%3BWolff%2C+Mary+S%3BLapinski%2C+Robert+H%3BTodd%2C+Andrew+C&rft.aulast=Berkowitz&rft.aufirst=Gertrud&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1673&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Bone; post-menopause; estrogen replacement therapy; menopause; Females; surgery; Lead; Hospitals; Blood levels; USA, New York, New York City; Egypt, Arab Rep., Sinai Peninsula ER - TY - JOUR T1 - Correspondence: PBDEs: Sjodin's Response. AN - 21398564; 12421264 AB - I appreciate Cleet's response to our paper concerning time trends of polybrominated diphenyl ethers (PBDEs) and related compounds in the U.S. population (Sjodin et al. 2004), and I appreciate the opportunity to address his comments. JF - Environmental Health Perspectives AU - A, Sjodin Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - a979 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Polybrominated diphenyl ethers KW - USA KW - polybrominated diphenyl ethers KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21398564?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+PBDEs%3A+Sjodin%27s+Response.&rft.au=A%2C+Sjodin&rft.aulast=A&rft.aufirst=Sjodin&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=a979&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Polybrominated diphenyl ethers; polybrominated diphenyl ethers; USA ER - TY - JOUR T1 - Correspondence: mercury levels in mothers. AN - 21389533; 12421266 AB - I read with great interest the excellent article by Mahaffey et al. (2004), which further describes the characteristics of the 1,709 women from the National Health and Nutrition Examination Survey (NHANES) 1999-2000 who were sampled for total and organic mercury levels in blood. It adds valuable detail to the initial report published last year (Schober et al. 2003). I would appreciate clarification on one important point: in the "Discussion," the authors cited a new analysis which indicates that the cord blood: maternal blood ratio is not 1:1 as assumed by the National Research Council (NRC) in 2000 (Committee on the Toxicological Effects of Methylmercury 2000), but rather 1.7:1. Using the same benchmark dose lower limit and uncertainty factor used by the NRC, Mahaffey et al. (2004) calculated that blood total mercury levels 3.5 microg/L in mothers could be associated with increased risk to the developing fetal nervous system. I am very interested in the details of this analysis and particularly in understanding why the uncertainty factor applied by the NRC to account in part for toxicokinetic variability does not compensate for uncertainty related to the cord blood:maternal blood mercury ratio. This is a critical concept because it has a dramatic impact on how many women may carry mercury levels in excess of what is believed to be safe for a fetus. JF - Environmental Health Perspectives AU - KM, Shea Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A978 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Methylmercury KW - benchmarks KW - Mercury KW - committees KW - Nutrition KW - Blood levels KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21389533?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+mercury+levels+in+mothers.&rft.au=KM%2C+Shea&rft.aulast=KM&rft.aufirst=Shea&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A978&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Methylmercury; benchmarks; committees; Mercury; Nutrition; Blood levels ER - TY - JOUR T1 - Sex and Ceruloplasmin Modulate the Response to Copper Exposure in Healthy Individuals AN - 21384095; 12425447 AB - Previous studies indicated that sex might influence the response to copper exposure. Ceruloplasmin (Cp) is an indicator of Cu status, but it is not clear whether and how it reflects changes of Cu status among healthy individuals. In this study, 82 apparently healthy women and men were chosen from 800 individuals because their Cp values belonged to the higher and lower 10% of the group Cp distribution curve. Before and after receiving a supplement of 10mg Cu/day (upper limit of daily intake) for 2 months, we performed blood and urinary biochemical measurement of potential Cu markers. We used principal component analysis and linear discriminant analysis to identify blood and/or urinary Cu indicators that showed a differential response to copper. Results showed that Cp values in serum represent a reliable indicator to differentiate subgroups within the normal population in their response to Cu exposure. The response depends on Cp values and on sex, such that women with higher and men with lower Cp values exhibit the greatest response. JF - Environmental Health Perspectives AU - Mendez, Marco A AU - Araya, Magdalena AU - Olivares, Manuel AU - Pizarro, Fernando AU - Gonzalez, Mauricio Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1654 EP - 1657 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Biochemistry KW - Urine KW - principal components analysis KW - Copper KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21384095?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Sex+and+Ceruloplasmin+Modulate+the+Response+to+Copper+Exposure+in+Healthy+Individuals&rft.au=Mendez%2C+Marco+A%3BAraya%2C+Magdalena%3BOlivares%2C+Manuel%3BPizarro%2C+Fernando%3BGonzalez%2C+Mauricio&rft.aulast=Mendez&rft.aufirst=Marco&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1654&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Biochemistry; principal components analysis; Urine; Copper ER - TY - JOUR T1 - Correspondence: The Human Population: Accepting Earth's Limitations. AN - 21375285; 12421265 AB - I thank Fowler and Hobbs for their letter (2004) and their research (2003). The view that a complexity of factors impacts human population growth certainly makes sense, and they have correctly pointed out that scientifically organized efforts to deal with human problems must take account of manifold interconnected events. Although it is necessary to recognize and acknowledge the complexities inherent in cultural life and the natural world, it is equally important that a dizzying array of variables not blind us to certain scientific facts of biophysical reality. Humankind is bound by such predominant facts because the workings of the world exist independently of human wishes and beliefs. JF - Environmental Health Perspectives AU - SE, Salmony Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A979 EP - A980 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - human populations KW - culture KW - ENA 13:Population Planning & Control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21375285?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+The+Human+Population%3A+Accepting+Earth%27s+Limitations.&rft.au=SE%2C+Salmony&rft.aulast=SE&rft.aufirst=Salmony&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A979&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - human populations; culture ER - TY - JOUR T1 - NIEHS News. AN - 21368799; 12421261 AB - Short articles on: Ethics in Environmental Health; Symposium Explores Children's Environments; Schwartz Named New NIEHS/NTP Director; Headliners: Air Pollution Impairs Lung Development in Children; Beyond the Bench: Help Instead of Hype. JF - Environmental Health Perspectives AU - T, Adler AU - MM, Dimes AU - J, Phelps AU - EE, Dooley Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A990 EP - A992 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Air pollution KW - Lung KW - Pollution effects KW - Environmental health KW - Children KW - environmental ethics KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21368799?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=NIEHS+News.&rft.au=T%2C+Adler%3BMM%2C+Dimes%3BJ%2C+Phelps%3BEE%2C+Dooley&rft.aulast=T&rft.aufirst=Adler&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A990&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Air pollution; Lung; Environmental health; Pollution effects; Children; environmental ethics ER - TY - JOUR T1 - SHRIMP U-Pb detrital zircon ages from Proterozoic and Early Palaeozoic sandstones and their bearing on the early geological evolution of Tasmania AN - 21339904; 6254218 AB - Detrital zircons from 13 Late Mesoproterozoic to Early Neoproterozoic sandstones and two Palaeozoic sandstones from Tasmania were dated in order to improve constraints on depositional ages, to test correlation between Proterozoic inliers, and to characterise source regions. These include successions considered to be the oldest presently exposed in Tasmania. Typical features of the age distributions of the Proterozoic rocks are prominent data concentrations at 1800-1650 Ma and 1450-1400 Ma, and a minor spread of Archaean ages. Statistical testing of the similarity of the age profiles shows that widespread quartzarenaceous samples from the Detention Subgroup, Needles Quartzite and from the Tyennan region are strongly similar, consistent with broad correlation. Relatively large differences are seen between the Detention Subgroup and the conformable, stratigraphically higher Jacob Quartzite, which contains an additional spread of 1300-1000 Ma zircons suggestive of a Grenvillian source. Age profiles of the quartzarenites and quartzwacke turbidites (Oonah Formation and correlatives) cannot be readily differentiated. The Oonah Formation likewise includes samples with and without Grenvillian ages, and there is no 750 Ma zircon population that would be expected if the turbidites were genetically related to the Wickham Orogeny. The simplest interpretation is that the quartzarenites (Rocky Cape Group and correlatives) and the turbidites (Oonah Formation and correlates) are lateral equivalents, although a younger (post-Wickham Orogeny) age for the Oonah Formation cannot be discounted. A maximum age of ca 1000 Ma is inferred for the Oonah Formation, Rocky Cape Group and correlatives. A minimum age of ca 750 Ma is provided by the basal age of the overlying Togari Group and correlatives. In a metasediment from western King Island, the youngest detrital zircons are ca 1350 Ma, allowing a pre-Grenvillian depositional age as suggested by previous dating of metamorphic monazite. However, the age profile of this sample is not dissimilar to the other Tasmanian successions that are inferred to be 1000-750 Ma. The Wings Sandstone, of southern Tasmania, contains an unusual profile dominated by Grenvillian ages, consistent with an allochthonous origin. Basement ages that broadly match the age spectra of the Tasmanian Proterozoic sediments are found in southwestern Laurentia, consistent with mutual proximity in Rodinia reconstructions. The Palaeozoic sandstones, from the turbiditic Mathinna Supergroup of northeastern Tasmania, have zircon age profiles typical of the Lachlan Fold Belt, with a predominant latest Neoproterozoic-Early Cambrian component and a lesser, broad Proterozoic data concentration at ca 1000 Ma. Western Tasmania was not a significant part of the source area for these rocks. JF - Australian Journal of Earth Sciences AU - Black, L P AU - Calver, C R AU - Seymour, D B AU - Reed, A AD - Minerals Division, Geoscience Australia, GPO Box 378, Canberra, ACT 2601, Australia; and Research School of Earth Sciences, Australian National University, ACT 0200, Australia Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 885 EP - 900 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 51 IS - 6 SN - 0812-0099, 0812-0099 KW - Microbiology Abstracts B: Bacteriology KW - Age KW - Data processing KW - Statistics KW - Islands KW - Dating KW - Wings KW - Succession KW - Evolution KW - Sediments KW - J 02410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21339904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Earth+Sciences&rft.atitle=SHRIMP+U-Pb+detrital+zircon+ages+from+Proterozoic+and+Early+Palaeozoic+sandstones+and+their+bearing+on+the+early+geological+evolution+of+Tasmania&rft.au=Wallace%2C+C+S%3BReitzenstein%2C+J%3BWithers%2C+G+S&rft.aulast=Wallace&rft.aufirst=C&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1294&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6088 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - SuppNotes - Figures, 5; tables, 1; references, 75. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Age; Islands; Statistics; Data processing; Dating; Wings; Succession; Sediments; Evolution DO - http://dx.doi.org/10.1111/j.1400-0952.2004.01091.x ER - TY - JOUR T1 - Fracture systems in granite pavements of the eastern Pilbara Craton, Western Australia: indicators of neotectonic activity? AN - 21339820; 6254215 AB - Continental Australia is characterised by high levels of seismic activity in comparison with intracratonic areas worldwide. However, the link between earthquake events and earthquake-related geomorphology in Australia remains poorly understood for all except the largest events, because landscape impact unambiguously attributable to seismic activity is difficult to recognise. In this context, we describe several unusual fracture systems of possible tectonic origin that transect granite pavements in the Archaean eastern Pilbara Craton of Western Australia. Occurring at four localities (Gallery Hill, North Shaw, Mulgandinnah Hill and Muccan) separated by up to 150 km, the fracture systems typically range up to 100 m in length and 20 m in width, locally offset pavement surfaces by up to 15 cm vertically, and expose uniformly fresh-looking rock. At one locality (Muccan), the fractures cross-cut two out of three generations of aboriginal petroglyphs etched into the pavement surface, which suggests that fracture formation occurred both recently and rapidly. All four localities are characterised by extensional structures (tension fractures and dilated joints) striking 020-040, and three preserve compressional structures (steeply dipping reverse faults at Gallery Hill and North Shaw; A-tent crestal fractures at Mulgandinnah Hill) trending 100-135. The strongly correlated alignments of the fracture systems militate against a purely weathering-controlled origin, and the observed pattern is compatible with fracture formation in a single East Pilbara-wide stress field, dominated by pure shear and characterised by northeast-southwest- to north-northeast-south-southwest-directed horizontal compression. This orientation is consistent with that derived by spatial averaging of existing stress orientation data from northwest Australia. These preliminary results have exciting implications for the inexpensive field-based determination of regional stress orientation, and for the use of granitic landforms in probabilistic seismic hazard assessment and the identification of earthquake-prone areas. JF - Australian Journal of Earth Sciences AU - Clark, D J AU - Bodorkos, S AD - Geoscience Australia, GPO Box 378, Canberra, ACT 2601, Australia Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 831 EP - 846 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 51 IS - 6 SN - 0812-0099, 0812-0099 KW - Microbiology Abstracts B: Bacteriology KW - Galleries KW - Earthquakes KW - Geomorphology KW - Data processing KW - Landscape KW - Fractures KW - Stress KW - Joints KW - Compression KW - J 02490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21339820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Earth+Sciences&rft.atitle=Fracture+systems+in+granite+pavements+of+the+eastern+Pilbara+Craton%2C+Western+Australia%3A+indicators+of+neotectonic+activity%3F&rft.au=Clark%2C+D+J%3BBodorkos%2C+S&rft.aulast=Clark&rft.aufirst=D&rft.date=2004-12-01&rft.volume=51&rft.issue=6&rft.spage=831&rft.isbn=&rft.btitle=&rft.title=Australian+Journal+of+Earth+Sciences&rft.issn=08120099&rft_id=info:doi/10.1111%2Fj.1400-0952.2004.01088.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - SuppNotes - Figures, 11; tables, 1; references, 52. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Earthquakes; Galleries; Data processing; Geomorphology; Landscape; Fractures; Stress; Compression; Joints DO - http://dx.doi.org/10.1111/j.1400-0952.2004.01088.x ER - TY - JOUR T1 - Late Miocene (U+Th)- super(4)He ages of ferruginous nodules from lateritic duricrust, Darling Range, Western Australia AN - 21335950; 6254219 AB - (U+Th)- super(4)He dates are presented for hematite-maghemite and hematite separates from pisolitic nodules from four rock specimens of lateritic duricrust sampled in an area of about 1 km super(2) in the Darling Range about 50 km northeast of Perth, where the duricrust forms a continuous cover over rocks of the Archaean Yilgarn Craton. Textures and compositions of the separates were checked by X-ray diffraction and scanning electron microscopy. Hematite-maghemite separates from three of the specimens yielded ages of about 10 Ma, identical within error (weighted mean, 9.9 c 0.9 Ma, 2s), whereas the hematite separate from the fourth specimen gave a U-He date of 7.5 Ma, all within the Late Miocene. While questions remain as to whether initial and boundary conditions of dating are adequately fulfilled, the iron oxide super(4)He dates are in good agreement with estimates by palaeomagnetic dating and other methods for the age of laterite formation in the Darling Range and other parts of south Western Australia. This study demonstrates the potential of (U+Th)- super(4)He dating as a serviceable, directly applicable tool for dating lateritic duricrust. JF - Australian Journal of Earth Sciences AU - Pidgeon, R T AU - Brander, T AU - Lippolt, HJ AD - Department of Applied Geology, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia, r.pidgeon@curtin.edu.au Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 901 EP - 909 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 51 IS - 6 SN - 0812-0099, 0812-0099 KW - Microbiology Abstracts B: Bacteriology KW - Scanning electron microscopy KW - Age KW - iron oxides KW - Dating KW - Boundaries KW - X-ray diffraction KW - Nodules KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21335950?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Earth+Sciences&rft.atitle=Late+Miocene+%28U%2BTh%29-+super%284%29He+ages+of+ferruginous+nodules+from+lateritic+duricrust%2C+Darling+Range%2C+Western+Australia&rft.au=Osornio-Vargas%2C+A+R%3BBonner%2C+J+C%3BAlfaro-Moreno%2C+E%3BMartinez%2C+L%3BGarcia-Cuellar%2C+C%3BPonce-de-Leon+Rosales%2C+S%3BMiranda%2C+J%3BRosas%2C+I&rft.aulast=Osornio-Vargas&rft.aufirst=A&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1289&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5913 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - SuppNotes - Figures, 4; tables, 1; references, 63. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Scanning electron microscopy; Age; iron oxides; Dating; Boundaries; X-ray diffraction; Nodules DO - http://dx.doi.org/10.1111/j.1400-0952.2004.01094.x ER - TY - JOUR T1 - Sediment transport in distributary channels and its export to the pro-deltaic environment in a tidally dominated delta: Fly River, Papua New Guinea AN - 21000758; 7489943 AB - Current metre deployments, suspended sediment measurements and surface sediment samples were collected from three locations within distributary channels of the tidally dominated Fly River delta in southern Papua New Guinea. Net bedload transport vectors and the occurrence of elongate tidal bars indicate that mutually evasive ebb- and flood-dominant transport zones occur in each of the distributary channels. Suspended sediment experiments at two locations show a phase relationship between tidal velocity and sediment concentration such that the net suspended sediment flux is directed seaward. Processes that control the export of fluid muds with concentrations up to 10gl-1 from the distributary channels across the delta front and onto the pro-delta are assessed in relation to the available data. Peak spring tidal current speeds (measured at 100cm above the bed) drop off from around 100cms-1 within the distributary channels to <50cms-1 on the delta front. Gravity-driven, 2-m thick, fluid mud layers generated in the distributary channels are estimated to require at least 35h to traverse the 20-km-wide, low-gradient (2X10-3 degrees) delta front. The velocities of such currents are well below those required for autosuspension. A 1-month time series of suspended sediment concentration and current velocity from the delta front indicates that tidal currents alone are unable to cause significant cross-delta mud transport. Wave-induced resuspension together with tides, storm surge and barotropic return-flow may play a role in maintaining the transport of fine sediment across the delta front, but insufficient data are available at present to make any reliable estimates. JF - Continental Shelf Research AU - Harris, Peter T AU - Hughes, Michael G AU - Baker, Elaine K AU - Dalrymple, Robert W AU - Keene, Jock B AD - Marine and Coastal Environment Group Geoscience Australia, GPO Box 378, Canberra, ACT 2601, Australia, Peter.Harris@ga.gov.au Y1 - 2004/12// PY - 2004 DA - December 2004 SP - 2431 EP - 2454 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 24 IS - 19 SN - 0278-4343, 0278-4343 KW - Aqualine Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts; Oceanic Abstracts KW - Bedload KW - Sediment transport KW - Suspended load KW - Autosuspension KW - Hyperpycnal flow KW - Turbidity KW - Mutually evasive KW - Deltaic KW - Tide-dominated KW - Deltas KW - Time series analysis KW - Resuspended sediments KW - Fluid mud KW - Continental shelves KW - Papua New Guinea, Fly R. KW - Sedimentation KW - Sediment Transport KW - Rivers KW - Suspended Sediments KW - Mud KW - Velocity KW - Export KW - Tidal currents KW - Channels KW - Sediment-water interface KW - Suspended matter in seawater KW - Fronts KW - Storm surges KW - Tidal Currents KW - ISEW, Papua New Guinea KW - AQ 00001:Water Resources and Supplies KW - Q2 09264:Sediments and sedimentation KW - SW 0835:Streamflow and runoff KW - O 3050:Sediment Dynamics KW - M2 551.466:Ocean Waves and Tides (551.466) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21000758?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Continental+Shelf+Research&rft.atitle=Sediment+transport+in+distributary+channels+and+its+export+to+the+pro-deltaic+environment+in+a+tidally+dominated+delta%3A+Fly+River%2C+Papua+New+Guinea&rft.au=Harris%2C+Peter+T%3BHughes%2C+Michael+G%3BBaker%2C+Elaine+K%3BDalrymple%2C+Robert+W%3BKeene%2C+Jock+B&rft.aulast=Harris&rft.aufirst=Peter&rft.date=2004-12-01&rft.volume=24&rft.issue=19&rft.spage=2431&rft.isbn=&rft.btitle=&rft.title=Continental+Shelf+Research&rft.issn=02784343&rft_id=info:doi/10.1016%2Fj.csr.2004.07.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Rivers; Resuspended sediments; Sediment-water interface; Fluid mud; Storm surges; Continental shelves; Sediment transport; Deltas; Sedimentation; Suspended matter in seawater; Fronts; Time series analysis; Tidal currents; Sediment Transport; Channels; Suspended Sediments; Tidal Currents; Velocity; Mud; Export; Papua New Guinea, Fly R.; ISEW, Papua New Guinea DO - http://dx.doi.org/10.1016/j.csr.2004.07.017 ER - TY - JOUR T1 - Estimated change in physical activity level (PAL) and prediction of 5-year weight change in men: the Aerobics Center Longitudinal Study AN - 17791719; 6111111 AB - To determine the relation between the average daily physical activity level (PAL) and the trajectory of weight change in men at risk for weight gain. Clinic-based cohort study over an average of 5 y. Healthy men (N = 2501) ages 20-55 y participating in the Aerobics Center Longitudinal Study who had received at least four medical examinations at the Cooper Clinic between 1970 and 1998. Daily leisure-time physical activity was reported and body weight was measured at all four examinations. The average daily PAL (METs 24 h super(-1)) was estimated from all activities, as well as from other incidental active and passive activities. Weight change over four examinations was regressed on the change in PAL between the first and third examinations. Random coefficient regression modeling indicated a curvilinear slope for weight gain over the follow-up among those maintaining the same PAL between the first and third examinations. Weight gain was further accelerated among men who decreased their activity. A shift from a low PAL ( 1.60 METs 24 h super(-1)) PAL was necessary for weight loss over time. Men with initially the lowest PAL had the greatest benefit from increasing activity. Daily PAL was inversely related to weight gain in this cohort. Increasing to or maintaining a daily PAL at least 60% above the resting metabolic rate (ie, PAL > 1.60 METs 24 h super(-1)) may be necessary to maintain body weight in middle-age and can be achieved by incorporating 45-60 min of brisk walking, gardening/yardwork, or cycling into the daily routine. JF - International Journal of Obesity AU - Di Pietro, L AU - Dziura, J AU - Blair, S N AD - John B. Pierce Laboratory, Yale University School of Medicine, 290 Congress Avenue, New Haven, CT 06519, USA, ldipietro@jbpierce.org Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1541 EP - 1547 VL - 28 IS - 12 SN - 0307-0565, 0307-0565 KW - Physical Education Index KW - Longitudinal studies KW - Obesity KW - Measurement KW - Weight control KW - Men KW - Walking KW - Basal metabolic rate KW - Exercise KW - Bicycling KW - Evaluation KW - Medical examinations KW - Weight KW - Activities KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17791719?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Obesity&rft.atitle=Estimated+change+in+physical+activity+level+%28PAL%29+and+prediction+of+5-year+weight+change+in+men%3A+the+Aerobics+Center+Longitudinal+Study&rft.au=Di+Pietro%2C+L%3BDziura%2C+J%3BBlair%2C+S+N&rft.aulast=Di+Pietro&rft.aufirst=L&rft.date=2004-12-01&rft.volume=28&rft.issue=12&rft.spage=1541&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Obesity&rft.issn=03070565&rft_id=info:doi/10.1038%2Fsj.ijo.0802821 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Weight; Men; Activities; Evaluation; Exercise; Longitudinal studies; Medical examinations; Weight control; Measurement; Obesity; Basal metabolic rate; Walking; Bicycling DO - http://dx.doi.org/10.1038/sj.ijo.0802821 ER - TY - JOUR T1 - Breeding System in a Population of Trigonella balansae (Leguminosae) AN - 17791282; 6076406 AB - BACKGROUND: and Aims Although some taxonomic studies in the genus Trigonella have been conducted, there has been no concerted effort to study the breeding system. This paper examines the floral structure and pollination system in a population of T. balansae, an annual pasture legume. METHODS: Floral morphology, hand and vector pollination, stigma receptivity, pollen tube growth, using scanning electron and fluorescence microscopy, were conducted. Key Results Measurements of floral structure from before to after anthesis indicates an inability for T. balansae to self-pollinate and a requirement for an external vector to effectively transfer pollen from the anthers onto the stigmas of this species. Seed set can be obtained by hand or honeybee manipulation of T. balansae flowers. CONCLUSIONS: Trigonella balansae is a self-compatible species, but which requires vectors such as honeybees to bring about pollination. JF - Annals of Botany AU - Nair, Ramakrishnan M AU - Dundas, Ian S AU - Wallwork, Meredith AU - Verlin, Dawn C AU - Waterhouse, Lyn AU - Dowling, Kate AD - South Australian Research & Development Institute (SARDI), GPO Box 397, Adelaide, SA 5001, Australia, School of Agriculture and Wine, University of Adelaide, Waite Campus, PMB 1, Glen Osmond, SA 5064, Australia, Adelaide Microscopy, University of Adelaide, Adelaide, SA 5005, Australia and BiometricsSA, SARDI, GPO Box 397, Adelaide, SA 5001, Australia Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 883 EP - 888 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 94 IS - 6 SN - 0305-7364, 0305-7364 KW - Ecology Abstracts KW - Pollination KW - Trigonella balansae KW - Anthers KW - Breeding KW - Legumes KW - Pasture KW - Stigma KW - Pollen KW - Reproductive strategy KW - D 04637:Legumes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17791282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Botany&rft.atitle=Breeding+System+in+a+Population+of+Trigonella+balansae+%28Leguminosae%29&rft.au=Nair%2C+Ramakrishnan+M%3BDundas%2C+Ian+S%3BWallwork%2C+Meredith%3BVerlin%2C+Dawn+C%3BWaterhouse%2C+Lyn%3BDowling%2C+Kate&rft.aulast=Nair&rft.aufirst=Ramakrishnan&rft.date=2004-12-01&rft.volume=94&rft.issue=6&rft.spage=883&rft.isbn=&rft.btitle=&rft.title=Annals+of+Botany&rft.issn=03057364&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Trigonella balansae; Pollination; Stigma; Breeding; Reproductive strategy; Anthers; Legumes; Pasture; Pollen ER - TY - JOUR T1 - Strain- and sex-related differences of carbonyl reductase activities in kidney microsomes and cytosol of rats AN - 17506460; 6403258 AB - This study was designed to elucidate strain- and sex-related differences of carbonyl reductase activity in rat kidney by using the oral antidiabetic drug acetohexamide as substrate. The frequency distribution of carbonyl reductase activities in kidney microsomes of male Fischer 344 (Fischer), Sprague-Dawley, Wistar and Wistar-Imamichi (Wistar-IM) rats exhibited a marked strain-related difference. Furthermore, the enzyme activities in kidney microsomes of Fischer, Sprague-Dawley and Wistar rats were male-specific, resulting in significant sex-related differences in these strains. There was no sex-related difference of carbonyl reductase activity in kidney microsomes of the Wistar-IM strain, which lacked its activity in both sexes. On the other hand, although carbonyl reductase activities were fully detectable in kidney cytosols from all the strains of male and female rats, no strain- or sex-related difference was observed among the cytosolic enzyme activities. These results provide new information for understanding the influence of internal factors on the renal metabolism of ketone-containing xenobiotics. JF - Journal of Applied Toxicology AU - Imamura, Y AU - Shimada, H AD - Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan, yorishig@gpo.kumamoto-u.ac.jp Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 437 EP - 441 VL - 24 IS - 6 SN - 0260-437X, 0260-437X KW - Carbonyl reductase KW - acetohexamide KW - Toxicology Abstracts KW - Microsomes KW - Cytosol KW - Kidney KW - Xenobiotics KW - Sex differences KW - Drugs KW - carbonyls KW - Metabolism KW - X 24117:Biochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17506460?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Toxicology&rft.atitle=Strain-+and+sex-related+differences+of+carbonyl+reductase+activities+in+kidney+microsomes+and+cytosol+of+rats&rft.au=Imamura%2C+Y%3BShimada%2C+H&rft.aulast=Imamura&rft.aufirst=Y&rft.date=2004-12-01&rft.volume=24&rft.issue=6&rft.spage=437&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Toxicology&rft.issn=0260437X&rft_id=info:doi/10.1002%2Fjat.996 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Kidney; Sex differences; carbonyls; Microsomes; Cytosol; Metabolism; Xenobiotics; Drugs DO - http://dx.doi.org/10.1002/jat.996 ER - TY - JOUR T1 - Management of exogenous threats to Antarctica and the sub-Antarctic Islands: balancing risks from TBT and non-indigenous marine organisms AN - 16187558; 6102332 AB - The discovery of high levels of tributyltin compounds in Antarctic marine sediments has prompted managers to consider the banning of such substances in this region. We propose that the banning of antifouling coatings may result in an increase in the risk of non-indigenous species invasions. Our studies show that un-treated vessels carry a more diverse community of fouling organisms than treated hulls on which fouling is restricted to specific untreated niches. Up to 40% of the species recruited to the hulls of Southern Ocean vessels are species with invasive histories. Viable fouling assemblages can survive prolonged voyages to high-latitude coastlines, yet passage through sea-ice may remove fouling communities due to mechanical abrasion reducing the hazard of introductions to ice-bound coastlines. The banning of antifouling compounds may be of particular concern for the ice-free sub-Antarctic islands which represent a common anchorage point for vessels on-route to Antarctica. JF - Marine Pollution Bulletin AU - Lewis, P N AU - Riddle, MJ AU - Hewitt, CL AD - Institute of Antarctic and Southern Ocean Studies (IASOS), University of Tasmania, GPO Box 252-77, Hobart, Tasmania 7001, Australia, plewis@utas.edu.au Y1 - 2004/12// PY - 2004 DA - December 2004 SP - 999 EP - 1005 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 49 IS - 11-12 SN - 0025-326X, 0025-326X KW - invasive species KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources; Toxicology Abstracts; Oceanic Abstracts; Aqualine Abstracts; Water Resources Abstracts; Pollution Abstracts KW - TBT KW - Bioinvasions KW - Antarctica KW - Sub-Antarctic islands KW - Fouling KW - Antifouling KW - Abrasion KW - Niches KW - Antarctic zone KW - Marine Sediments KW - Biota KW - Ship hulls KW - Fouling organisms KW - Ice KW - Tin compounds KW - Anchorages KW - Tributyltin KW - PS, Antarctica KW - Community composition KW - PS, Antarctic Ocean KW - Organotin compounds KW - Dispersion KW - Risk assessment KW - Antarctic KW - Risks KW - Hazards KW - Islands KW - History KW - Ecosystem management KW - Polar waters KW - Marine KW - Toxicity KW - Polar environments KW - Risk KW - Sea ice KW - Fouling control KW - Antifouling substances KW - Oceans KW - Nature conservation KW - Marine organisms KW - Introduced species KW - Coatings KW - Q5 08523:Conservation, wildlife management and recreation KW - O 4090:Conservation and Environmental Protection KW - X 24166:Environmental impact KW - Q2 09181:General KW - P 1000:MARINE POLLUTION KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16187558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Pollution+Bulletin&rft.atitle=Management+of+exogenous+threats+to+Antarctica+and+the+sub-Antarctic+Islands%3A+balancing+risks+from+TBT+and+non-indigenous+marine+organisms&rft.au=Lewis%2C+P+N%3BRiddle%2C+MJ%3BHewitt%2C+CL&rft.aulast=Lewis&rft.aufirst=P&rft.date=2004-12-01&rft.volume=49&rft.issue=11-12&rft.spage=999&rft.isbn=&rft.btitle=&rft.title=Marine+Pollution+Bulletin&rft.issn=0025326X&rft_id=info:doi/10.1016%2Fj.marpolbul.2004.07.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-02-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Tin compounds; Anchorages; Toxicity; Risks; Tributyltin; Hazards; Antarctic zone; Sea ice; Biota; Community composition; Antifouling substances; Fouling control; Nature conservation; Ecosystem management; Polar waters; Marine organisms; Ship hulls; Introduced species; Fouling organisms; Dispersion; Fouling; Risk assessment; Ice; Islands; Polar environments; Organotin compounds; Risk; Marine Sediments; Abrasion; History; Oceans; Niches; Antarctic; Coatings; PS, Antarctica; Antarctica; PS, Antarctic Ocean; Marine DO - http://dx.doi.org/10.1016/j.marpolbul.2004.07.001 ER - TY - JOUR T1 - The Effects of the World Trade Center Event on Birth Outcomes Among Term Deliveries at Three Lower Manhattan Hospitals AN - 14720930; 10672912 AB - Birth outcomes were assessed for women in the New York City area who lived or worked in the vicinity of the World Trade Center (WTC) at the time of the September 2001 terrorist attack and during the following weeks. Data were obtained from three large Lower Manhattan hospitals with maternity units. Results revealed that term infants of women residing within a 2-mi radius of the WTC during the four weeks after the attack weighed, on average, 149 g less than term infants born to women residing outside the area. Infants born to residents were also, on average, 0.82 cm shorter than those born to women living outside the area. No significant association was found for head circumference or for length of gestation, but women who were in the first trimester of pregnancy on September 11 delivered, on average, 3.6 d earlier than women in later stages of pregnancy. JF - Environmental Health Perspectives AU - Lederman, Sally Ann AU - Rauh, Virginia AU - Weiss, Lisa AU - Stein, Janet L AU - Hoepner, Lori A AU - Becker, Mark AU - Perera, Frederica P Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1772 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AREA COMPARISONS KW - BIOMASS KW - REPRODUCTION, HUMAN KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14720930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Effects+of+the+World+Trade+Center+Event+on+Birth+Outcomes+Among+Term+Deliveries+at+Three+Lower+Manhattan+Hospitals&rft.au=Lederman%2C+Sally+Ann%3BRauh%2C+Virginia%3BWeiss%2C+Lisa%3BStein%2C+Janet+L%3BHoepner%2C+Lori+A%3BBecker%2C+Mark%3BPerera%2C+Frederica+P&rft.aulast=Lederman&rft.aufirst=Sally&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1772&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AREA COMPARISONS; BIOMASS; REPRODUCTION, HUMAN; NEW YORK CITY ER - TY - JOUR T1 - Prenatal DDT Exposure in Relation to Anthropometric and Pubertal Measures in Adolescent Males AN - 14718558; 10672910 AB - Selected subjects from the Philadelphia Blood Pressure Project were studied to explore the effects of prenatal exposure to DDTs on anthropometric and pubertal measures in adolescent males. Anthropometric measurements up to 20 yr of age were used, and maternal serum samples from the third trimester were analyzed for DDT concentrations. Results showed that the concentrations of p,p'-DDE in maternal serum during pregnancy ranged 125 mu g/g lipid, while the other two DDT compounds were found at lower levels, but the concentrations of all three compounds were correlated. Results from statistical modeling showed no statistically significant effects of p,p'-DDE, p,p'-DDT, or o,p'-DDT on the anthropometric or pubertal measures in the adolescent males. JF - Environmental Health Perspectives AU - Gladen, Beth C AU - Klebanoff, Mark A AU - Hediger, Mary L AU - Katz, Solomon H AU - Barr, Dana B AU - Davis, Mark D AU - Longnecker, Matthew P Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1761 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - PHYSIOLOGICAL EFFECTS, HUMAN KW - REPRODUCTION, HUMAN KW - DDT KW - DDE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prenatal+DDT+Exposure+in+Relation+to+Anthropometric+and+Pubertal+Measures+in+Adolescent+Males&rft.au=Gladen%2C+Beth+C%3BKlebanoff%2C+Mark+A%3BHediger%2C+Mary+L%3BKatz%2C+Solomon+H%3BBarr%2C+Dana+B%3BDavis%2C+Mark+D%3BLongnecker%2C+Matthew+P&rft.aulast=Gladen&rft.aufirst=Beth&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1761&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; PHYSIOLOGICAL EFFECTS, HUMAN; DDE; DDT; REPRODUCTION, HUMAN ER - TY - JOUR T1 - The Sources of Inflammatory Mediators in the Lung After Silica Exposure AN - 14718543; 10672899 AB - To understand the role of inflammatory mediators in silica-induced pathology, the expression of several inflammatory mediators in alveolar macrophages (AMs) was studies after in vitro exposure to silica or after in vivo exposure by intratracheal instillation. The expression was studied in specific pathogen-free SpragueDawley rats at the message level by real-time reverse transcription polymerase chain reaction and, where appropriate, at the protein level by enzyme-linked immunosorbent assays. In addition, the interactions between AMs and type II cells or fibroblasts were studied in in vitro culture systems. Results showed that exposure of AMs to silica in vitro increased the message levels of only three genes: interleukin-6, monocyte chemoattractant protein-1, and macrophage inflammatory protein-2. In addition, when mRNA levels were measured in bronchoalveolar lavage cells harvested from rats instilled with silica, the mRNA levels of four other genes-granulocyte/macrophage-colony stimulating factor, interleukin-1 beta , interleukin-10, and inducible nitric oxide synthase-also went up. JF - Environmental Health Perspectives AU - Murali Krishna Rao, K AU - Porter, Dale W AU - Meighan, Terence AU - Castranova, Vince Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1679 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - PROTEIN SYNTHESIS KW - PULMONARY EFFECTS KW - SILICON COMPOUNDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718543?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Sources+of+Inflammatory+Mediators+in+the+Lung+After+Silica+Exposure&rft.au=Murali+Krishna+Rao%2C+K%3BPorter%2C+Dale+W%3BMeighan%2C+Terence%3BCastranova%2C+Vince&rft.aulast=Murali+Krishna+Rao&rft.aufirst=K&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1679&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 12 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; PROTEIN SYNTHESIS; PULMONARY EFFECTS; SILICON COMPOUNDS ER - TY - JOUR T1 - Incorporating Environmental Health into Pediatric Medical and Nursing Education AN - 14718487; 10672909 AB - Leading health institutions have called for improvements in the environmental health education for health professionals, and several medical and nursing organizations have supported environmental health education for such professionals by endorsing the Health Professionals and Environmental Health Education Position Statement of the National Environmental Education and Training Foundation. To address the need, two working groups of pediatric physicians and nurses conducted an assessment of and identified points of insertion in the current medical and nursing education structures where environmental health content could be incorporated. These strategic opportunities are identified, providing a comprehensive list of insertion points to guide medical and nursing education accrediting bodies, licensing bodies, and other key personnel who determine and influence medical and nursing curricula. JF - Environmental Health Perspectives AU - McCurdy, Leyla Erk AU - Roberts, James AU - Rogers, Bonnie AU - Love, Rebecca AU - Etzel, Ruth AU - Paulson, Jerome AU - Witherspoon, Nsedu Obot Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1755 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CURRICULUM KW - EDUCATION, UNIVERSITY KW - PUBLIC HEALTH KW - HEALTH, ENV KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718487?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Incorporating+Environmental+Health+into+Pediatric+Medical+and+Nursing+Education&rft.au=McCurdy%2C+Leyla+Erk%3BRoberts%2C+James%3BRogers%2C+Bonnie%3BLove%2C+Rebecca%3BEtzel%2C+Ruth%3BPaulson%2C+Jerome%3BWitherspoon%2C+Nsedu+Obot&rft.aulast=McCurdy&rft.aufirst=Leyla&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1755&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CURRICULUM; EDUCATION, UNIVERSITY; PUBLIC HEALTH; HEALTH, ENV ER - TY - JOUR T1 - Environmental Health Disparities: a Framework Integrating Psychosocial and Environmental Concepts AN - 14718479; 10672894 JF - Environmental Health Perspectives AU - Gee, Gilbert C AU - Payne-Sturges, Devon C Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1645 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SOCIOECONOMIC IMPACT ASSESSMENT KW - PUBLIC HEALTH KW - ECOLOGY, HUMAN KW - CHEMICAL CONTAMINATION KW - ENV QUALITY ASSESSMENT KW - ENV JUSTICE KW - RACIAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718479?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Environmental+Health+Disparities%3A+a+Framework+Integrating+Psychosocial+and+Environmental+Concepts&rft.au=Gee%2C+Gilbert+C%3BPayne-Sturges%2C+Devon+C&rft.aulast=Gee&rft.aufirst=Gilbert&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1645&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOCIOECONOMIC IMPACT ASSESSMENT; ENV JUSTICE; PUBLIC HEALTH; ECOLOGY, HUMAN; RACIAL COMPARISONS; CHEMICAL CONTAMINATION; ENV QUALITY ASSESSMENT ER - TY - JOUR T1 - Pulmonary Epithelial Integrity in Children: Relationship to Ozone Exposure and Swimming Pool Attendance AN - 14718363; 10672911 AB - In Umea, Sweden, pulmonary epithelial integrity in children was studied during May 2002 and related to ozone exposure and swimming-pool attendance. Lung function measurements were performed, and peripheral blood samples were obtained for analysis of Clara cell protein (CC16) in serum. Nearly 40% of the children were regular indoor pool visitors. Outdoor O sub(3) was monitored continuously at the university campus where the children spent time outdoors. Results showed that O sub(3) levels ranged 77116 mu g/m super(3), and the levels did not have any adverse effect on forced expiratory volume in 1 s. Significantly lower levels of serum CC16 were found in pool visitors compared with controls, which suggested adverse effects on Clara cells. No significant differences were found in the levels of CC16 before and after outdoor exercise, and no statistically significant relationships were found between CC16 levels in serum and ambient O sub(3) exposure. JF - Environmental Health Perspectives AU - Lagerkvist, Birgitta Json AU - Bernard, Alfred AU - Blomberg, Anders AU - Bergstrom, Erik AU - Forsberg, Bertil AU - Holmstrom, Karin AU - Karp, Kjell Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1768 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SWEDEN KW - CHLORINATION KW - SWIMMING POOLS KW - PULMONARY EFFECTS KW - OZONE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pulmonary+Epithelial+Integrity+in+Children%3A+Relationship+to+Ozone+Exposure+and+Swimming+Pool+Attendance&rft.au=Lagerkvist%2C+Birgitta+Json%3BBernard%2C+Alfred%3BBlomberg%2C+Anders%3BBergstrom%2C+Erik%3BForsberg%2C+Bertil%3BHolmstrom%2C+Karin%3BKarp%2C+Kjell&rft.aulast=Lagerkvist&rft.aufirst=Birgitta&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1768&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SWEDEN; CHLORINATION; SWIMMING POOLS; PULMONARY EFFECTS; OZONE ER - TY - JOUR T1 - Association of Chromosomal Alterations with Arsenite-Induced Tumorigenicity of Human HaCaT Keratinocytes in Nude Mice AN - 14718033; 10672903 AB - An immortalized but nontumorigenic human skin keratinocyte cell line, HaCaT, was exposed to low-dose inorganic trivalent arsenite for a long period, and conversion of the cells from nontumorigenic to tumorigenic was assessed by injecting the arsenite-exposed cells into nude mice. Chromosomal alterations in the cell lines established from the resulting tumors were analyzed using the comparative genomic hybridization technique. Results showed that the nontumorigenic cells were converted into cells that were tumorigenic. Histology of the tumors showed epithelial hyperplasia, mild dysplasia, severe dysplasia, and invasive carcinoma, which are similar to arsenic-induced skin pathology. Long-term exposure of HaCaT cells to low doses of arsenite resulted in an increase in intracellular glutathione levels and resistance to arsenite challenges. The increased frequency of micronuclei observed in A1 and A2 cells showed that long-term exposure to low-dose arsenite caused chromosomal damage. A gain of chromosome 4q and a loss of chromosome 9q were observed in most of the cell lines established. JF - Environmental Health Perspectives AU - Chien, Chia-Wen AU - Chiang, Ming-Chang AU - Ho, I-Ching AU - Lee, Te-Chang Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1704 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - CYTOTOXICITY KW - ARSENIC KW - TUMORIGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718033?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+of+Chromosomal+Alterations+with+Arsenite-Induced+Tumorigenicity+of+Human+HaCaT+Keratinocytes+in+Nude+Mice&rft.au=Chien%2C+Chia-Wen%3BChiang%2C+Ming-Chang%3BHo%2C+I-Ching%3BLee%2C+Te-Chang&rft.aulast=Chien&rft.aufirst=Chia-Wen&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1704&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; CYTOTOXICITY; ARSENIC; TUMORIGENIC AGENTS ER - TY - JOUR T1 - GIS Modeling of Air Toxics Releases from TRI-Reporting and Non-TRI-Reporting Facilities: Impacts for Environmental Justice AN - 14717522; 10672905 AB - Air toxics releases from Toxic Release Inventory (TRI)-reporting and -nonreporting facilities were modeled using dispersion modeling and geographic information system (GIS) analysis at four levels of geographic resolution. The study region was Durham County, NC, which represents a broad range of values across demographic, socioeconomic, and social indicators. The four geographic levels were ZIP code, census tract, census block group, and census block. An employee-based emissions algorithm was generated to impute emissions to TRI-nonreporting facilities. Results indicated that the inclusive modeling of all facilities significantly altered the magnitude and spatial distribution of modeled air concentrations, as modeling all sites together, rather than modeling TRI sites alone, increased the magnitude of the modeled concentrations, especially in areas with no TRI facilities. JF - Environmental Health Perspectives AU - Dolinoy, Dana C AU - Miranda, Marie Lynn Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1717 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MATHEMATIC MODELS, AIR KW - SPATIAL COMPARISONS KW - NORTH CAROLINA KW - AIR TOXICS KW - DATA REPORTING, MANDATORY KW - ENV JUSTICE KW - STACK EMISSIONS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14717522?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=GIS+Modeling+of+Air+Toxics+Releases+from+TRI-Reporting+and+Non-TRI-Reporting+Facilities%3A+Impacts+for+Environmental+Justice&rft.au=Dolinoy%2C+Dana+C%3BMiranda%2C+Marie+Lynn&rft.aulast=Dolinoy&rft.aufirst=Dana&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1717&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; MATHEMATIC MODELS, AIR; GEOGRAPHIC INFORMATION SYSTEMS; STACK EMISSIONS; NORTH CAROLINA; SPATIAL COMPARISONS; AIR TOXICS; DATA REPORTING, MANDATORY ER - TY - JOUR T1 - Use of Pharmacokinetic Modeling to Design Studies for Pathway-Specific Exposure Model Evaluation AN - 14716498; 10672902 AB - Pharmacokinetic modeling was used to guide the design of a field study to evaluate a pathway-specific model using urinary metabolites measured in overnight voids of children. The children's dietary intake model for pesticide exposure was used. The major problem in assessing children's dietary exposure is that young children often touch foods with their hands before consumption, which increases the contamination of the food and their intake of contaminants through the diet. Computer simulation results indicated three important aspects for a successful design: longitudinal design of the study, short half-life of the selected chemical, and high pesticide surface loading. The results showed that the use of pharmacokinetic modeling can allow better planning of field efforts to collect data, as well as reduce the study costs. JF - Environmental Health Perspectives AU - Hu, Ye AU - Akland, Gerry G AU - Pellizzari, Edo D AU - Berry, Maurice R AU - Melnyk, Lisa Jo Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1697 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DESIGN KW - DIET KW - MATHEMATIC MODELS, BIOLOGICAL KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716498?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Use+of+Pharmacokinetic+Modeling+to+Design+Studies+for+Pathway-Specific+Exposure+Model+Evaluation&rft.au=Hu%2C+Ye%3BAkland%2C+Gerry+G%3BPellizzari%2C+Edo+D%3BBerry%2C+Maurice+R%3BMelnyk%2C+Lisa+Jo&rft.aulast=Hu&rft.aufirst=Ye&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1697&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DESIGN; DIET; MATHEMATIC MODELS, BIOLOGICAL; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Estimating the Independent Effects of Multiple Pollutants in the Presence of Measurement Error: an Application of a Measurement-Error-Resistant Technique AN - 14716452; 10672900 AB - An approach has been developed recently that uses hierarchical modeling to assess exposurehealth outcome associations, which is resistant to exposure measurement error. The method was used to examine the independent effects of PM sub(10) and several gaseous air pollutants on daily deaths, using recent data and results from the National Mortality and Morbidity Air Pollution Study conducted across 90 US cities. The hierarchical model is provided. When averaged over the results for each different pollutant, important associations appeared for PM sub(10) and carbon monoxide. For sulfur dioxide, the effects were found to vary greatly, with an overall estimate of 0.1% increase in daily mortality, while no effect on daily mortality was found for nitrogen dioxide. JF - Environmental Health Perspectives AU - Zeka, Ariana AU - Schwartz, Joel Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1686 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SULFUR DIOXIDE KW - NITROGEN DIOXIDE KW - AIR POLLUTION EFFECTS KW - QUANTITATIVE ANALYSIS KW - CARBON MONOXIDE KW - URBAN ATMOSPHERE KW - PARTICULATES KW - MORTALITY PATTERNS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forest+Ecology+and+Management&rft.atitle=Growth+and+stem+form+responses+of+plantation-grown+Acacia+melanoxylon+%28R.+Br.%29+to+form+pruning+and+nurse-crop+thinning&rft.au=Medhurst%2C+J+L%3BPinkard%2C+E+A%3BBeadle%2C+CL%3BWorledge%2C+D&rft.aulast=Medhurst&rft.aufirst=J&rft.date=2003-07-03&rft.volume=179&rft.issue=1-3&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Forest+Ecology+and+Management&rft.issn=03781127&rft_id=info:doi/10.1016%2FS0378-1127%2802%2900521-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NITROGEN DIOXIDE; SULFUR DIOXIDE; AIR POLLUTION EFFECTS; QUANTITATIVE ANALYSIS; CARBON MONOXIDE; MORTALITY PATTERNS; PARTICULATES; URBAN ATMOSPHERE ER - TY - JOUR T1 - Temporal Variability of Urinary Phthalate Metabolite Levels in Men of Reproductive Age AN - 14715747; 10672907 AB - The temporal variability in urinary phthalate metabolite levels was investigated in 11 men. Up to ten spot urine samples were collected during three cycles over a 92-d period. Substantial within-subject variability in urinary phthalate metabolite levels was found, but the sensitivity of a single spot urine sample to predict three-month average phthalate exposure was found to be moderate to high. However, the collection of additional urine samples one to three months apart improved the prediction of a subject's three-month average exposure. A single urine sample was more predictive for monoethyl phthalate than for mono-(2-ethylhexyl) phthalate. JF - Environmental Health Perspectives AU - Hauser, Russ AU - Meeker, John D AU - Park, Sohee AU - Silva, Manori J AU - Calafat, Antonia M Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1734 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOLOGICAL INDICATORS KW - PHTHALIC ACID ESTERS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14715747?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Temporal+Variability+of+Urinary+Phthalate+Metabolite+Levels+in+Men+of+Reproductive+Age&rft.au=Hauser%2C+Russ%3BMeeker%2C+John+D%3BPark%2C+Sohee%3BSilva%2C+Manori+J%3BCalafat%2C+Antonia+M&rft.aulast=Hauser&rft.aufirst=Russ&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1734&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 10 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOLOGICAL INDICATORS; PHTHALIC ACID ESTERS; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Synergistic Embryotoxicity of Polycyclic Aromatic Hydrocarbon Aryl Hydrocarbon Receptor Agonists with Cytochrome P4501A Inhibitors in Fundulus heterclitus AN - 14714209; 10672896 AB - While a strong, positive relationship has been found between the ability of PAHs to bind the aryl hydrocarbon receptor (AHR) and their induction of cytochrome P4501A (CYP1A), conclusions regarding the role of the AHR pathway and CYP1A activity in the toxicity of PAHs have been less clear. In this study, killifish Fundulus heteroclitus embryos were treated with three different AHR agonists and four CYP1A inhibitors that work by various mechanisms, and the embryos were analyzed for in ovo CYP1A activity and for deformities. A wide range of concentrations of AHR agonists were used to elicit a range of ethoxyresorufin O-deethylase inductions with and without inducing deformities. Results indicated that co-exposure to PAH-type AHR agonists and CYP1A inhibitors consistently enhanced embryotoxicity beyond levels predicted by an additive toxicity model. The inhibitors used in the study, which included PCB 126, benzo(a)pyrene, and beta -naphthoflavone, caused similar increases in PAH toxicity, although the inhibitors varied in structure and mechanism of inhibition. JF - Environmental Health Perspectives AU - Wassenberg, Deena M AU - Di Giulio, Richard T Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1658 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PHYSIOLOGICAL RESPONSES, FISH KW - PROTEIN SYNTHESIS KW - POLYCYCLIC AROMATIC HYDROCARBON KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14714209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Synergistic+Embryotoxicity+of+Polycyclic+Aromatic+Hydrocarbon+Aryl+Hydrocarbon+Receptor+Agonists+with+Cytochrome+P4501A+Inhibitors+in+Fundulus+heterclitus&rft.au=Wassenberg%2C+Deena+M%3BDi+Giulio%2C+Richard+T&rft.aulast=Wassenberg&rft.aufirst=Deena&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1658&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; PHYSIOLOGICAL RESPONSES, FISH; PROTEIN SYNTHESIS; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Epidemiology of Health Effects of Radiofrequency Exposure AN - 14713958; 10672908 JF - Environmental Health Perspectives AU - Ahlbom, Anders AU - Green, Adele AU - Kheifets, Leeka AU - Savitz, David AU - Swerdlow, Anthony Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1741 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PUBLIC HEALTH KW - ELECTROMAGNETIC FIELDS KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713958?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Epidemiology+of+Health+Effects+of+Radiofrequency+Exposure&rft.au=Ahlbom%2C+Anders%3BGreen%2C+Adele%3BKheifets%2C+Leeka%3BSavitz%2C+David%3BSwerdlow%2C+Anthony&rft.aulast=Ahlbom&rft.aufirst=Anders&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1741&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PUBLIC HEALTH; ELECTROMAGNETIC FIELDS; LITERATURE SURVEYS ER - TY - CPAPER T1 - Characterization of clays used in the ceramic manufacturing industry by reflectance spectroscopy AN - 39906430; 3893996 AU - de Senna, JA AU - Fo, CRS Y1 - 2004/11/19/ PY - 2004 DA - 2004 Nov 19 KW - CPI, Conference Papers Index KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39906430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Characterization+of+clays+used+in+the+ceramic+manufacturing+industry+by+reflectance+spectroscopy&rft.au=de+Senna%2C+JA%3BFo%2C+CRS&rft.aulast=de+Senna&rft.aufirst=JA&rft.date=2004-11-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ICAM 2004, c/o Federal Inst. for Geosciences and Natural Resources, B4.15 Inorganic Geochemistry, Stilleweg 2, D-30655 Hannover, Germany; URL: www.icam2004.org N1 - Last updated - 2010-05-03 ER - TY - GEN T1 - Mexico's Counter-narcotics Efforts under Fox, December 2000 to October 2004 AN - 1679099229; MD01536 AB - Reviews projects and provides information on status of Mexican and U.S.-Mexico bilateral counternarcotics efforts after first four years of President Fox's administration. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2004 SP - 16 KW - Arrest KW - Cocaine KW - Congressional oversight KW - Corruption KW - Crop eradication KW - Drug certification KW - Drug seizures KW - Drug traffic KW - Extradition KW - Heroin KW - Laundering of funds KW - Law enforcement cooperation KW - Marijuana KW - Methamphetamine KW - Operation Trifecta KW - Villanueva Madrid, Mario KW - Fox Quesada, Vicente KW - Bush, George W. KW - Villanueva Madrid, Mario KW - Fox Quesada, Vicente KW - Bush, George W. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679099229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_md&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Mexico%27s+Counter-narcotics+Efforts+under+Fox%2C+December+2000+to+October+2004&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2004-11-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ L2 - http://fpc.state.gov/c18183.htm. LA - English DB - Digital National Security Archive N1 - Name - Mexico-United States High-Level Contact Group for Drug Control; Mexico. Attorney General's Office; Mexico. Attorney General's Office. Federal Investigation Agency; United States. Department of State. Bureau of International Narcotics and Law Enforcement Affairs N1 - Analyte descriptor - NSA document type: Report; Location of original: Available [Online]: State Department, Bureau of Public Affairs Foreign Press Centers N1 - People - Bush, George W.; Fox Quesada, Vicente; Villanueva Madrid, Mario N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - Snoring in primary school children and domestic environment: a Perth school based study. AN - 67177921; 15527500 AB - The home is the predominant environment for exposure to many environmental irritants such as air pollutants and allergens. Exposure to common indoor irritants including volatile organic compounds, formaldehyde and nitrogen dioxide, may increase the risk of snoring for children. The aim of this study was to investigate domestic environmental factors associated with snoring in children. A school-based respiratory survey was administered during March and April of 2002. Nine hundred and ninety six children from four primary schools within the Perth metropolitan area were recruited for the study. A sub-group of 88 children aged 4-6 years were further selected from this sample for domestic air pollutant assessment. The prevalences of infrequent snoring and habitual snoring in primary school children were 24.9% and 15.2% respectively. Passive smoking was found to be a significant risk factor for habitual snoring (odds ratio (OR) = 1.77; 95% confidence interval (CI): 1.20-2.61), while having pets at home appeared to be protective against habitual snoring (OR = 0.58; 95% CI: 0.37-0.92). Domestic pollutant assessments showed that the prevalence of snoring was significantly associated with exposure to nitrogen dioxide during winter. Relative to the low exposure category ( 60 microg/m3) to NO2 were 2.5 (95% CI: 0.7-8.7) and 4.5 (95% CI: 1.4-14.3) respectively. The corresponding linear dose-response trend was also significant (P = 0.011). Snoring is common in primary school children. Domestic environments may play a significant role in the increased prevalence of snoring. Exposure to nitrogen dioxide in domestic environment is associated with snoring in children. JF - Respiratory research AU - Zhang, Guicheng AU - Spickett, Jeffery AU - Rumchev, Krassi AU - Lee, Andy H AU - Stick, Stephen AD - School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia. zhangg@exchange.curtin.edu.au Y1 - 2004/11/04/ PY - 2004 DA - 2004 Nov 04 SP - 19 VL - 5 KW - Air Pollutants KW - 0 KW - Tobacco Smoke Pollution KW - Index Medicus KW - Australia -- epidemiology KW - Risk Factors KW - Humans KW - Health Status KW - Surveys and Questionnaires KW - Child KW - Air Pollutants -- analysis KW - Schools -- statistics & numerical data KW - Male KW - Female KW - Comorbidity KW - Prevalence KW - Child, Preschool KW - Asthma -- epidemiology KW - Population KW - Snoring -- epidemiology KW - Risk Assessment -- methods KW - Air Pollution, Indoor -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67177921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Respiratory+research&rft.atitle=Snoring+in+primary+school+children+and+domestic+environment%3A+a+Perth+school+based+study.&rft.au=Zhang%2C+Guicheng%3BSpickett%2C+Jeffery%3BRumchev%2C+Krassi%3BLee%2C+Andy+H%3BStick%2C+Stephen&rft.aulast=Zhang&rft.aufirst=Guicheng&rft.date=2004-11-04&rft.volume=5&rft.issue=&rft.spage=19&rft.isbn=&rft.btitle=&rft.title=Respiratory+research&rft.issn=1465-993X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-03-14 N1 - Date created - 2004-12-13 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Arch Environ Health. 2001 Sep-Oct;56(5):433-8 [11777024] Pediatrics. 2002 Apr;109(4):e69 [11927742] Pediatrics. 2003 Mar;111(3):554-63 [12612236] Monaldi Arch Chest Dis. 2002 Jun-Aug;57(3-4):161-3 [12619373] Singapore Med J. 2002 Nov;43(11):554-6 [12683350] BMJ. 1999 Sep 25;319(7213):815-9 [10496824] Chest. 2003 May;123(5):1561-6 [12740274] Lancet. 2003 Jun 7;361(9373):1939-44 [12801737] Chest. 2003 Aug;124(2):587-93 [12907547] J Pediatr. 2003 Apr;142(4):377-82 [12712054] Chest. 2003 Nov;124(5):1709-15 [14605039] Sleep. 2004 Mar 15;27(2):274-8 [15124722] Thorax. 2004 Sep;59(9):746-51 [15333849] Am Ind Hyg Assoc J. 1976 OCT;37(10):570-7 [983946] Biochem Pharmacol. 1988 Apr 15;37(8):1497-507 [3358780] BMJ. 1989 Dec 16;299(6714):1491-4 [2514859] Am Rev Respir Dis. 1990 May;141(5 Pt 1):1119-26 [2339834] Chest. 1997 Jan;111(1):170-3 [8996012] Clin Exp Allergy. 1999 May;29(5):611-7 [10231320] Respir Med. 2001 May;95(5):423-9 [11392586] Math Biosci. 2001 Mar;170(1):79-90 [11259804] Arch Otolaryngol Head Neck Surg. 2000 Apr;126(4):481-6 [10772301] Chest. 2001 Dec;120(6):1930-5 [11742924] Pediatr Pulmonol. 2001 Sep;32(3):222-7 [11536452] Occup Environ Med. 2003 Nov;60(11):892-6 [14573722] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Female-biased sex allocation in peregrine falcons and other raptors AN - 754566174; 13413365 AB - The sex ratios of nestling Falconiformes in which males are smaller than females are often female biased, despite the apparent costs involved in producing very large female offspring. In Australian peregrine falcons, Falco peregrinus, this bias is most pronounced in broods produced early in the season, and the first eggs to be laid are most likely to produce females. Females that lay early are most likely to be successful breeders. Very large chicks tend to occur in female-biased broods. Collectively, these data suggest that females likely to produce large offspring produce daughters. A modified version of the Trivers/Willard hypothesis is suggested to account for this pattern. JF - Behavioral Ecology and Sociobiology AU - Olsent, Penny D AU - Cockburn, Andrew AD - Department of Zoology, Australian National University, GPO Box 4, ACT 2601, Canberra City, Australia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 417 EP - 423 PB - Springer-Verlag, Heidelberger Platz 3 Berlin 14197 Germany VL - 28 IS - 6 SN - 0340-5443, 0340-5443 KW - Ecology Abstracts; Animal Behavior Abstracts KW - Falco peregrinus KW - Data processing KW - Sex ratio KW - Falconiformes KW - Progeny KW - Eggs KW - Sex KW - Y 25040:Behavioral Ecology KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754566174?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Behavioral+Ecology+and+Sociobiology&rft.atitle=Female-biased+sex+allocation+in+peregrine+falcons+and+other+raptors&rft.au=Olsent%2C+Penny+D%3BCockburn%2C+Andrew&rft.aulast=Olsent&rft.aufirst=Penny&rft.date=2004-11-01&rft.volume=28&rft.issue=6&rft.spage=417&rft.isbn=&rft.btitle=&rft.title=Behavioral+Ecology+and+Sociobiology&rft.issn=03405443&rft_id=info:doi/10.1007%2FBF00164123 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Data processing; Sex ratio; Progeny; Eggs; Sex; Falco peregrinus; Falconiformes DO - http://dx.doi.org/10.1007/BF00164123 ER - TY - JOUR T1 - Foreign relations of the United States, 1952-1954: Guatemala AN - 37987154; 2865220 JF - Diplomatic history AU - Rabe, Stephen G AU - Rabe, Stephen G Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 785 EP - 790 PB - US Government Printing Office VL - 28 IS - 5 SN - 0145-2096, 0145-2096 KW - Political Science KW - International relations KW - Guatemala KW - History of international relations KW - U.S.A. KW - Foreign relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37987154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Diplomatic+history&rft.atitle=Foreign+relations+of+the+United+States%2C+1952-1954%3A+Guatemala&rft.au=Rabe%2C+Stephen+G&rft.aulast=Rabe&rft.aufirst=Stephen&rft.date=2004-11-01&rft.volume=28&rft.issue=5&rft.spage=785&rft.isbn=&rft.btitle=&rft.title=Diplomatic+history&rft.issn=01452096&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 6784; 5906 6784; 5205; 433 293 14; 156 84 14 ER - TY - JOUR T1 - Using Decision Forest to Classify Prostate Cancer Samples on the Basis of SELDI-TOF MS Data: Assessing Chance Correlation and Prediction Confidence AN - 21430966; 12425813 AB - Class prediction using "omics" data is playing an increasing role in toxicogenomics, diagnosis/prognosis, and risk assessment. These data are usually noisy and represented by relatively few samples and a very large number of predictor variables (e.g., genes of DNA microarray data or m/z peaks of mass spectrometry data). These characteristics manifest the importance of assessing potential random correlation and overfitting of noise for a classification model based on omics data. We present a novel classification method, decision forest (DF), for class prediction using omics data. DF combines the results of multiple heterogeneous but comparable decision tree (DT) models to produce a consensus prediction. The method is less prone to overfitting of noise and chance correlation. A DF model was developed to predict presence of prostate cancer using a proteomic data set generated from surface-enhanced laser deposition/ionization time-of-flight mass spectrometry (SELDI-TOF MS). The degree of chance correlation and prediction confidence of the model was rigorously assessed by extensive cross-validation and randomization testing. Comparison of model prediction with imposed random correlation demonstrated biologic relevance of the model and the reduction of overfitting in DF. Furthermore, two confidence levels (high and low confidences) were assigned to each prediction, where most misclassifications were associated with the low-confidence region. For the high-confidence prediction, the model achieved 99.2% sensitivity and 98.2% specificity. The model also identified a list of significant peaks that could be useful for biomarker identification. DF should be equally applicable to other omics data such as gene expression data or metabolomic data. The DF algorithm is available upon request. JF - Environmental Health Perspectives AU - Tong, Weida AU - Xie, Qian AU - Hong, Huixiao AU - Fang, Hong Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1622 EP - 1627 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Bioindicators KW - Risk assessment KW - Sensitivity KW - classification KW - Noise levels KW - Forests KW - Mass spectrometry KW - Lasers KW - prostate cancer KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21430966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+Decision+Forest+to+Classify+Prostate+Cancer+Samples+on+the+Basis+of+SELDI-TOF+MS+Data%3A+Assessing+Chance+Correlation+and+Prediction+Confidence&rft.au=Tong%2C+Weida%3BXie%2C+Qian%3BHong%2C+Huixiao%3BFang%2C+Hong&rft.aulast=Tong&rft.aufirst=Weida&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1622&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Risk assessment; Bioindicators; Sensitivity; classification; Noise levels; Mass spectrometry; Forests; Lasers; prostate cancer ER - TY - JOUR T1 - Lung Cancer in Railroad Workers Exposed to Diesel Exhaust AN - 21430214; 12429301 AB - Diesel exhaust has been suspected to be a lung carcinogen. The assessment of this lung cancer risk has been limited by lack of studies of exposed workers followed for many years. In this study, we assessed lung cancer mortality in 54,973 U.S. railroad workers between 1959 and 1996 (38 years). By 1959, the U.S. railroad industry had largely converted from coal-fired to diesel-powered locomotives. We obtained work histories from the U.S. Railroad Retirement Board, and ascertained mortality using Railroad Retirement Board, Social Security, and Health Care Financing Administration records. Cause of death was obtained from the National Death Index and death certificates. There were 43,593 total deaths including 4,351 lung cancer deaths. Adjusting for a healthy worker survivor effect and age, railroad workers in jobs associated with operating trains had a relative risk of lung cancer mortality of 1.40 (95% confidence interval, 1.30-1.51). Lung cancer mortality did not increase with increasing years of work in these jobs. Lung cancer mortality was elevated in jobs associated with work on trains powered by diesel locomotives. Although a contribution from exposure to coal combustion products before 1959 cannot be excluded, these results suggest that exposure to diesel exhaust contributed to lung cancer mortality in this cohort. Key words: diesel exhaust, lung cancer, occupational exposure. JF - Environmental Health Perspectives AU - Garshick, Eric AU - Laden, Francine AU - Hart, Jaime E AU - Rosner, Bernard Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1539 EP - 1543 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Mortality KW - USA KW - locomotives KW - Combustion products KW - Railroads KW - Diesel engines KW - Cancer KW - Occupational exposure KW - Lung cancer KW - Exhaust emissions KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21430214?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lung+Cancer+in+Railroad+Workers+Exposed+to+Diesel+Exhaust&rft.au=Garshick%2C+Eric%3BLaden%2C+Francine%3BHart%2C+Jaime+E%3BRosner%2C+Bernard&rft.aulast=Garshick&rft.aufirst=Eric&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1539&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Mortality; locomotives; Combustion products; Railroads; Diesel engines; Occupational exposure; Cancer; Exhaust emissions; Lung cancer; USA ER - TY - JOUR T1 - The Relationship between Housing and Health: Children at Risk AN - 21423192; 12429288 AB - In November 2002, the National Center for Healthy Housing convened a 2-day workshop to review the state of knowledge in the field of healthy housing. The workshop, supported with funds from the U.S. Centers for Disease Control and Prevention's National Center for Injury Prevention and Control and National Center for Environmental Health, was unique in that it focused solely on the effect of housing on children's health and the translation of research findings into practical activities in home construction, rehabilitation, and maintenance. Participants included experts and practitioners representing the health, housing, and environmental arenas. Presentations by subject-matter experts covered four key areas: asthma, neurotoxicants, injury, and translational research. Panel discussions followed the presentations, which generated robust dialogue on potential future research opportunities and overall policy gaps. Lack of consensus on standard measurements, incomplete understanding about the interaction of home hazards, inadequate research on the effectiveness of interventions, and insufficient political support limit current efforts to achieve healthy housing. However, change is forthcoming and achievable. Key words: asthma, childhood exposure, environmental toxicants, healthy housing, lead poisoning. JF - Environmental Health Perspectives AU - Breysse, Patrick AU - Farr, Nick AU - Galke, Warren AU - Lanphear, Bruce Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1583 EP - 1588 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - USA KW - Housing KW - Injuries KW - Toxicants KW - Politics KW - prevention KW - Asthma KW - Respiratory diseases KW - Children KW - Lead KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423192?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+between+Housing+and+Health%3A+Children+at+Risk&rft.au=Breysse%2C+Patrick%3BFarr%2C+Nick%3BGalke%2C+Warren%3BLanphear%2C+Bruce&rft.aulast=Breysse&rft.aufirst=Patrick&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1583&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Toxicants; Injuries; Housing; Politics; prevention; Asthma; Respiratory diseases; Children; Lead; USA ER - TY - JOUR T1 - Subchronic Exposure to TCDD, PeCDF, PCB126, and PCB153: Effect on Hepatic Gene Expression AN - 21422649; 12425814 AB - We employed DNA microarray to identify unique hepatic gene expression patterns associated with subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other halogenated aromatic hydrocarbons (HAHs). Female Harlan Sprague-Dawley rats were exposed for 13 weeks to toxicologically equivalent doses of four different HAHs based on the toxic equivalency factor of each chemical: TCDD (100 ng/kg/day), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF; 200 ng/kg/day), 3,3',4,4',5-pentachlorobiphenyl (PCB126; 1,000 ng/kg/day), or 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153; 1,000 microg/kg/day). Global gene expression profiles for each exposure, which account for 8,799 gene probe sets contained on Affymetrix RGU34A GeneChips, were compared by principal components analysis. The aryl hydrocarbon receptor (AhR) ligands TCDD, PeCDF, and PCB126 produced very similar global gene expression profiles that were unique from the nonAhR ligand PCB153, underscoring the extensive impact of AhR activation and/or the resulting hepatic injury on global gene expression in female rat liver. Many genes were co-expressed during the 13-week TCDD, PeCDF, or PCB126 exposures, including classical AhR-regulated genes and some genes not previously characterized as being AhR regulated, such as carcinoembryonic-cell adhesion molecule 4 (C-CAM4) and adenylate cyclase-associated protein 2 (CAP2). Real-time reverse-transcriptase polymerase chain reaction confirmed the increased expression of these genes in TCDD-, PeCDF-, and PCB126-exposed rats as well as the up- or down-regulation of several other novel dioxin-responsive genes. In summary, DNA microarray successfully identified dioxin-responsive genes expressed after exposure to AhR ligands (TCDD, PeCDF, PCB126) but not after exposure to the non-AhR ligand PCB153. Together, these findings may help to elucidate some of the fundamental features of dioxin toxicity and may further clarify the biologic role of the AhR signaling pathway. JF - Environmental Health Perspectives AU - Vezina, Chad M AU - Walker, Nigel J AU - Olson, James R Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1636 EP - 1644 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Rats KW - principal components analysis KW - DNA KW - Liver KW - TCDD KW - Proteins KW - Toxicity KW - aromatic hydrocarbons KW - Dioxins KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21422649?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Subchronic+Exposure+to+TCDD%2C+PeCDF%2C+PCB126%2C+and+PCB153%3A+Effect+on+Hepatic+Gene+Expression&rft.au=Vezina%2C+Chad+M%3BWalker%2C+Nigel+J%3BOlson%2C+James+R&rft.aulast=Vezina&rft.aufirst=Chad&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1636&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Rats; principal components analysis; Liver; DNA; Proteins; TCDD; Toxicity; Dioxins; aromatic hydrocarbons ER - TY - JOUR T1 - Lead Sources in Human Diet in Greenland AN - 21422565; 12429305 AB - Although blood lead levels have declined in Greenland, they are still elevated despite the fact that lead levels in the Greenland environment are very low. Fragments of lead shot in game birds have been suggested as an important source of dietary exposure, and meals of sea birds, particularly eider, contain high concentrations of lead. In a cross-sectional population survey in Greenland in 1993-1994, blood lead adjusted for age and sex was found to be associated with the reported consumption of sea birds. Participants reporting less than weekly intake of sea birds had blood lead concentrations of approximately 75 microg/L, whereas those who reported eating sea birds several times a week had concentrations of approximately 110 microg/L, and those who reported daily intake had concentrations of 170 microg/L (p = 0.01). Blood lead was not associated with dietary exposure to other local or imported food items. JF - Environmental Health Perspectives AU - Bjerregaard, Peter AU - Johansen, Poul AU - Mulvad, Gert AU - Pedersen, Henning Sloth AU - Hansen, Jens C Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1496 EP - 1498 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - Aves KW - Diets KW - Biological surveys KW - Marine KW - Age KW - Marine birds KW - Population structure KW - Lead KW - AN, Greenland KW - Blood levels KW - Q5 08504:Effects on organisms KW - ENA 12:Oceans & Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21422565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lead+Sources+in+Human+Diet+in+Greenland&rft.au=Bjerregaard%2C+Peter%3BJohansen%2C+Poul%3BMulvad%2C+Gert%3BPedersen%2C+Henning+Sloth%3BHansen%2C+Jens+C&rft.aulast=Bjerregaard&rft.aufirst=Peter&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1496&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Biological surveys; Diets; Marine birds; Population structure; Aves; Age; Lead; Blood levels; AN, Greenland; Marine ER - TY - JOUR T1 - Systems Biology: The Big Picture AN - 21418266; 12425811 AB - Systems biology-a field that draws from mathematics, engineering, nanotechnology, and computer science--is poised to take biology to a new level as it offers understanding of the wealth of data flowing from the "omics" fields. Systems biology looks at the data produced by genomics, proteomics, and metabolomics studies, and visualizes how an organism's biological processes intertwine to produce a whole greater than the sum of its parts. A working model of an entire biological system could impart enormous power for learning how environmental exposures result in disease. Today, practitioners are working to define their field--for example, its terminology and analytical tools--in an attempt to make their efforts pay off. JF - Environmental Health Perspectives AU - Spivey, Angela Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A938 EP - A943 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - nanotechnology KW - ENA 06:Food & Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21418266?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Systems+Biology%3A+The+Big+Picture&rft.au=Spivey%2C+Angela&rft.aulast=Spivey&rft.aufirst=Angela&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A938&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - nanotechnology ER - TY - JOUR T1 - In Vivo Imaging of Activated Estrogen Receptors in Utero by Estrogens and Bisphenol A AN - 21417205; 12429292 AB - Environmental estrogens are of particular concern when exposure occurs during embryonic development. Although there are good models to study estrogenic activity of chemicals in adult animals, developmental exposure is much more difficult to test. The weak estrogenic activity of the environmental estrogen bisphenol A (BPA) in embryos is controversial. We have recently generated transgenic mice that carry a reporter construct with estrogen-responsive elements coupled to luciferase. We show that, using this in vivo model in combination with the IVIS imaging system, activation of estrogen receptors (ERs) by maternally applied BPA and other estrogens can be detected in living embryos in utero. Eight hours after exposure to 1 mg/kg BPA, ER transactivation could be significantly induced in the embryos. This was more potent than would be estimated from in vitro assays, although its intrinsic activity is still lower than that of diethylstilbestrol and 17beta-estradiol dipropionate. On the basis of these results, we conclude that the estrogenic potency of BPA estimated using in vitro assays might underestimate its estrogenic potential in embryos. JF - Environmental Health Perspectives AU - Lemmen, Josephine G AU - Arends, Roel J AU - van der Saag, Paul T AU - van der Burg, Bart Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1544 EP - 1549 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Chemicals KW - bisphenol A KW - Embryos KW - Mice KW - estrogens KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21417205?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=In+Vivo+Imaging+of+Activated+Estrogen+Receptors+in+Utero+by+Estrogens+and+Bisphenol+A&rft.au=Lemmen%2C+Josephine+G%3BArends%2C+Roel+J%3Bvan+der+Saag%2C+Paul+T%3Bvan+der+Burg%2C+Bart&rft.aulast=Lemmen&rft.aufirst=Josephine&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1544&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Chemicals; bisphenol A; Mice; Embryos; estrogens ER - TY - JOUR T1 - Mass Spectrometry Group Has Mass Appeal AN - 21407171; 12425815 AB - The field of proteomics seeks to define, on a global scale, the levels, activities, regulation, and interaction of proteins in a biological sample. Proteomics is analogous to transcriptomics--the global analysis of mRNA transcripts that arise from the expression of genes in the genome--although the former is considerably more complicated. Whereas the human genome comprises approximately 30,000 genes, there are likely over 100,000 unique proteins in the human proteome due to the multiple ways each gene can be transcribed and translated into proteins by cellular machinery. JF - Environmental Health Perspectives AU - Eubanks, Mary Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A936 EP - A937 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Machinery KW - Proteins KW - Mass spectrometry KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21407171?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Mass+Spectrometry+Group+Has+Mass+Appeal&rft.au=Eubanks%2C+Mary&rft.aulast=Eubanks&rft.aufirst=Mary&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A936&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Machinery; Mass spectrometry; Proteins ER - TY - JOUR T1 - Listing Occupational Carcinogens AN - 21406583; 12429306 AB - The occupational environment has been a most fruitful one for investigating the etiology of human cancer. Many recognized human carcinogens are occupational carcinogens. There is a large volume of epidemiologic and experimental data concerning cancer risks in different work environments. It is important to synthesize this information for both scientific and public health purposes. Various organizations and individuals have published lists of occupational carcinogens. However, such lists have been limited by unclear criteria for which recognized carcinogens should be considered occupational carcinogens, and by inconsistent and incomplete information on the occupations and industries in which the carcinogenic substances may be found and on their target sites of cancer. Based largely on the evaluations published by the International Agency for Research on Cancer, and augmented with additional information, the present article represents an attempt to summarize, in tabular form, current knowledge on occupational carcinogens, the occupations and industries in which they are found, and their target organs. We have considered 28 agents as definite occupational carcinogens, 27 agents as probable occupational carcinogens, and 113 agents as possible occupational carcinogens. These tables should be useful for regulatory or preventive purposes and for scientific purposes in research priority setting and in understanding carcinogenesis. JF - Environmental Health Perspectives AU - Siemiatycki, Jack AU - Richardson, Lesley AU - Straif, Kurt AU - Latreille, Benoit Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1447 EP - 1459 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Etiology KW - Carcinogenicity KW - Carcinogenesis KW - Carcinogens KW - Organs KW - Cancer KW - Public health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406583?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Listing+Occupational+Carcinogens&rft.au=Siemiatycki%2C+Jack%3BRichardson%2C+Lesley%3BStraif%2C+Kurt%3BLatreille%2C+Benoit&rft.aulast=Siemiatycki&rft.aufirst=Jack&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1447&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Etiology; Carcinogenicity; Carcinogenesis; Carcinogens; Organs; Cancer; Public health ER - TY - JOUR T1 - Production of Androgens by Microbial Transformation of Progesterone in Vitro: A Model for Androgen Production in Rivers Receiving Paper Mill Effluent AN - 21405990; 12429303 AB - We have previously documented the presence of progesterone and androstenedione in the water column and bottom sediments of the Fenholloway River, Taylor County, Florida. This river receives paper mill effluent and contains masculinized female mosquitofish. We hypothesized that plant sterols (e.g., ss-sitosterol) derived from the pulping of pine trees are transformed by bacteria into progesterone and subsequently into 17alpha-hydroxyprogesterone, androstenedione, and other androgens. In this study, we demonstrate that these same androgens can be produced in vitro from the bacterium Mycobacterium smegmatis. In a second part to this study, we reextracted and reanalyzed the sediment from the Fenholloway River and verified the presence of androstadienedione, a delta1 steroid with androgen activity. JF - Environmental Health Perspectives AU - Jenkins, Ronald L AU - Wilson, Elizabeth M AU - Angus, Robert A AU - Howell, W Mike Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1508 EP - 1511 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Rivers KW - USA, Florida, Fenholloway R. KW - paper mills KW - USA, Florida KW - Trees KW - water column KW - steroids KW - Effluents KW - Sediments KW - Mycobacterium smegmatis KW - ENA 19:Water Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21405990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Production+of+Androgens+by+Microbial+Transformation+of+Progesterone+in+Vitro%3A+A+Model+for+Androgen+Production+in+Rivers+Receiving+Paper+Mill+Effluent&rft.au=Jenkins%2C+Ronald+L%3BWilson%2C+Elizabeth+M%3BAngus%2C+Robert+A%3BHowell%2C+W+Mike&rft.aulast=Jenkins&rft.aufirst=Ronald&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1508&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Rivers; paper mills; Trees; water column; steroids; Effluents; Sediments; Mycobacterium smegmatis; USA, Florida, Fenholloway R.; USA, Florida ER - TY - JOUR T1 - The TAO-Gen Algorithm for Identifying Gene Interaction Networks with Application to SOS Repair in E. coli AN - 21379205; 12425816 AB - One major unresolved issue in the analysis of gene expression data is the identification and quantification of gene regulatory networks. Several methods have been proposed for identifying gene regulatory networks, but these methods predominantly focus on the use of multiple pairwise comparisons to identify the network structure. In this article, we describe a method for analyzing gene expression data to determine a regulatory structure consistent with an observed set of expression profiles. Unlike other methods this method goes beyond pairwise evaluations by using likelihood-based statistical methods to obtain the network that is most consistent with the complete data set. The proposed algorithm performs accurately for moderate-sized networks with most errors being minor additions of linkages. However, the analysis also indicates that sample sizes may need to be increased to uniquely identify even moderate-sized networks. The method is used to evaluate interactions between genes in the SOS signaling pathway in Escherichia coli using gene expression data where each gene in the network is over-expressed using plasmids inserts. JF - Environmental Health Perspectives AU - Yamanaka, Takeharu AU - Toyoshiba, Hiroyoshi AU - Sone, Hideko AU - Parham, Frederick M AU - Portier, Christopher J Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1614 EP - 1621 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Genetics KW - Escherichia coli KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21379205?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+TAO-Gen+Algorithm+for+Identifying+Gene+Interaction+Networks+with+Application+to+SOS+Repair+in+E.+coli&rft.au=Yamanaka%2C+Takeharu%3BToyoshiba%2C+Hiroyoshi%3BSone%2C+Hideko%3BParham%2C+Frederick+M%3BPortier%2C+Christopher+J&rft.aulast=Yamanaka&rft.aufirst=Takeharu&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1614&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Genetics; Escherichia coli ER - TY - JOUR T1 - Phenotypic Anchoring of Gene Expression Changes during Estrogen-Induced Uterine Growth AN - 21379172; 12425809 AB - A major challenge in the emerging field of toxicogenomics is to define the relationships between chemically induced changes in gene expression and alterations in conventional toxicologic parameters such as clinical chemistry and histopathology. We have explored these relationships in detail using the rodent uterotrophic assay as a model system. Gene expression levels, uterine weights, and histologic parameters were analyzed 1, 2, 4, 8, 24, 48, and 72 hr after exposure to the reference physiologic estrogen 17 beta-estradiol (E2). A multistep analysis method, involving unsupervised hierarchical clustering followed by supervised gene ontology-driven clustering, was used to define the transcriptional program associated with E2-induced uterine growth and to identify groups of genes that may drive specific histologic changes in the uterus. This revealed that uterine growth and maturation are preceded and accompanied by a complex, multistage molecular program. The program begins with the induction of genes involved in transcriptional regulation and signal transduction and is followed, sequentially, by the regulation of genes involved in protein biosynthesis, cell proliferation, and epithelial cell differentiation. Furthermore, we have identified genes with common molecular functions that may drive fluid uptake, coordinated cell division, and remodeling of luminal epithelial cells. These data define the mechanism by which an estrogen induces organ growth and tissue maturation, and demonstrate that comparison of temporal changes in gene expression and conventional toxicology end points can facilitate the phenotypic anchoring of toxicogenomic data. JF - Environmental Health Perspectives AU - Moggs, Jonathan G AU - Tinwell, Helen AU - Spurway, Tracey AU - Chang, Hur-Song Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1589 EP - 1606 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Biosynthesis KW - Growth KW - Histopathology KW - Proteins KW - cell differentiation KW - Organs KW - rodents KW - Toxicology KW - estrogens KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21379172?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Phenotypic+Anchoring+of+Gene+Expression+Changes+during+Estrogen-Induced+Uterine+Growth&rft.au=Moggs%2C+Jonathan+G%3BTinwell%2C+Helen%3BSpurway%2C+Tracey%3BChang%2C+Hur-Song&rft.aulast=Moggs&rft.aufirst=Jonathan&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1589&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Biosynthesis; Growth; Proteins; Histopathology; cell differentiation; Organs; Toxicology; rodents; estrogens ER - TY - JOUR T1 - Renal Toxicogenomic Response to Chronic Uranyl Nitrate Insult in Mice AN - 21372690; 12425810 AB - Although the nephrotoxicity of uranium has been established through numerous animal studies, relatively little is known about the effects of long-term environmental uranium exposure. Using a combination of conventional biochemical studies and serial analysis of gene expression (SAGE), we examined the renal responses to uranyl nitrate (UN) chronic exposure. Renal uranium levels were significantly increased 4 months after ingestion of uranium in drinking water. Creatinine levels in serum were slightly but significantly increased compared with those in controls. Although no further significant differences in other parameters were noted, substantial molecular changes were observed in toxicogenomic profiles. UN induced dramatic alterations in expression levels of more than 200 genes, mainly up-regulated, including oxidative-response-related genes, genes encoding for cellular metabolism, ribosomal proteins, signal transduction, and solute transporters. Seven differentially expressed transcripts were confirmed by real-time quantitative polymerase chain reaction. In addition, significantly increased peroxide levels support the implication of oxidative stress in UN toxicant response. This report highlights the potential of SAGE for the discovery of novel toxicant-induced gene expression alterations. Here, we present, for the first time, a comprehensive view of renal molecular events after uranium long-term exposure. JF - Environmental Health Perspectives AU - Taulan, Magali AU - Paquet, Francois AU - Maubert, Christophe AU - Delissen, Olivia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1628 EP - 1635 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Nitrates KW - Biochemistry KW - Toxicants KW - Uranium KW - Proteins KW - Drinking water KW - Ingestion KW - Metabolism KW - oxidative stress KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21372690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Renal+Toxicogenomic+Response+to+Chronic+Uranyl+Nitrate+Insult+in+Mice&rft.au=Taulan%2C+Magali%3BPaquet%2C+Francois%3BMaubert%2C+Christophe%3BDelissen%2C+Olivia&rft.aulast=Taulan&rft.aufirst=Magali&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1628&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Toxicants; Biochemistry; Nitrates; Uranium; Proteins; Ingestion; Drinking water; oxidative stress; Metabolism ER - TY - JOUR T1 - Organochlorine Exposure and Colorectal Cancer Risk AN - 21371556; 12429297 AB - Organochlorine compounds have been linked to increased risk of several cancers. Despite reductions in their use and fugitive release, they remain one of the most important groups of persistent pollutants to which humans are exposed, primarily through dietary intake. We designed a case-control study to assess the risk of colorectal cancer with exposure to these chemicals, and their potential interactions with genetic alterations in the tumors. A subsample of cases (n = 132) and hospital controls (n = 76) was selected from a larger case-control study in Barcelona, Catalonia, Spain. We measured concentrations in serum of several organochlorines by gas chromatography. We assessed point mutations in K-ras and p53 genes in tissue samples by polymerase chain reaction/single-strand conformation polymorphism and assessed expression of p53 protein by immunohistochemical methods. An elevated risk of colorectal cancer was associated with higher serum concentrations of mono-ortho polychlorinated biphenyl (PCB) congeners 28 and 118. The odds ratio for these mono-ortho PCBs for middle and higher tertile were, respectively, 1.82 [95% confidence interval (CI), 0.90-3.70] and 2.94 (95% CI, 1.39-6.20). Alpha-hexachlorocyclohexane, hexachlorobenzene, and p,p'-DDE (4,4'-dichlorodiphenyltrichloroethene) showed nonsignificant increases in risk. Risk associated with mono-ortho PCBs was slightly higher for tumors with mutations in the p53 gene but was not modified by mutations in K-ras. Mono-ortho PCBs were further associated with transversion-type mutations in both genes. These results generate the hypothesis that exposure to mono-ortho PCBs contributes to human colorectal cancer development. The trend and magnitude of the association, as well as the observation of a molecular fingerprint in tumors, raise the possibility that this finding may be causal. JF - Environmental Health Perspectives AU - Howsam, Mike AU - Grimalt, Joan O AU - Guino, Elisabet AU - Navarro, Matilde Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1460 EP - 1466 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Chemicals KW - Diets KW - Organochlorine compounds KW - colorectal carcinoma KW - tumors KW - Spain, Catalonia KW - Spain, Cataluna, Barcelona KW - PCB compounds KW - Mutation KW - Cancer KW - Hospitals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21371556?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Pre-+and+Postnatal+Exposure+to+Polychlorinated+Biphenyls%3A+Lessons+from+the+Inuit+Cohort+Study&rft.au=Ayotte%2C+Pierre%3BMuckle%2C+Gina%3BJacobson%2C+Joseph+L%3BJacobson%2C+Sandra+W%3BDewailly%2C+Eric&rft.aulast=Ayotte&rft.aufirst=Pierre&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1253&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Diets; Chemicals; Organochlorine compounds; colorectal carcinoma; tumors; Mutation; PCB compounds; Cancer; Hospitals; Spain, Catalonia; Spain, Cataluna, Barcelona ER - TY - JOUR T1 - Assessing Ozone-Related Health Impacts under a Changing Climate AN - 21370890; 12429290 AB - Climate change may increase the frequency and intensity of ozone episodes in future summers in the United States. However, only recently have models become available that can assess the impact of climate change on O3 concentrations and health effects at regional and local scales that are relevant to adaptive planning. We developed and applied an integrated modeling framework to assess potential O3-related health impacts in future decades under a changing climate. The National Aeronautics and Space Administration-Goddard Institute for Space Studies global climate model at 4 degrees x 5 degrees resolution was linked to the Penn State/National Center for Atmospheric Research Mesoscale Model 5 and the Community Multiscale Air Quality atmospheric chemistry model at 36 km horizontal grid resolution to simulate hourly regional meteorology and O3 in five summers of the 2050s decade across the 31-county New York metropolitan region. We assessed changes in O3-related impacts on summer mortality resulting from climate change alone and with climate change superimposed on changes in O3 precursor emissions and population growth. Considering climate change alone, there was a median 4.5% increase in O3-related acute mortality across the 31 counties. Incorporating O3 precursor emission increases along with climate change yielded similar results. When population growth was factored into the projections, absolute impacts increased substantially. Counties with the highest percent increases in projected O3 mortality spread beyond the urban core into less densely populated suburban counties. This modeling framework provides a potentially useful new tool for assessing the health risks of climate change. JF - Environmental Health Perspectives AU - Knowlton, Kim AU - Rosenthal, Joyce E AU - Hogrefe, Christian AU - Lynn, Barry Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1557 EP - 1563 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Mortality KW - population growth KW - Climatic changes KW - Emissions KW - Population density KW - summer KW - Air quality KW - metropolitan areas KW - USA, New York KW - Ozone KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21370890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessing+Ozone-Related+Health+Impacts+under+a+Changing+Climate&rft.au=Knowlton%2C+Kim%3BRosenthal%2C+Joyce+E%3BHogrefe%2C+Christian%3BLynn%2C+Barry&rft.aulast=Knowlton&rft.aufirst=Kim&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1557&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Mortality; population growth; Climatic changes; Population density; Emissions; summer; Air quality; metropolitan areas; Ozone; USA, New York ER - TY - JOUR T1 - 112-16, 2004: toxicogenomics forum. AN - 21368839; 12421270 AB - Articles: * The Year of the Rat * Getting to the Core of Antimicrobialse * Tackling Innate Immunity * Cellular Jigsaw Puzzles * txgNet: Y.F. Leung's Functional Genomics. JF - Environmental Health Perspectives AU - E, Hood AU - E, Susman AU - C, Potera AU - R, Dahl AU - EE, Dooley Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A930 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts; Environmental Engineering Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21368839?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=112-16%2C+2004%3A+toxicogenomics+forum.&rft.au=E%2C+Hood%3BE%2C+Susman%3BC%2C+Potera%3BR%2C+Dahl%3BEE%2C+Dooley&rft.aulast=E&rft.aufirst=Hood&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A930&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - EHP 112-16, 2004: Toxicogenomics Science Selections - Template for Toxicants: Gene Expression Varies by Cell Type, How E2 Induces Uterine Effects: Transcription Coordinates Cascade. AN - 21361971; 12421269 AB - Toxicogenomics Science Selections - Template for Toxicants: Gene Expression Varies by Cell Type, How E2 Induces Uterine Effects: Transcription Coordinates Cascade. JF - Environmental Health Perspectives AU - JR, Barrett Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A944 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Toxicants KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21361971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=EHP+112-16%2C+2004%3A+Toxicogenomics+Science+Selections+-+Template+for+Toxicants%3A+Gene+Expression+Varies+by+Cell+Type%2C+How+E2+Induces+Uterine+Effects%3A+Transcription+Coordinates+Cascade.&rft.au=JR%2C+Barrett&rft.aulast=JR&rft.aufirst=Barrett&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A944&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Toxicants ER - TY - JOUR T1 - Induced innovations and climate change policy AN - 20523386; 6192952 AB - With the recent progress in Bonn and Marrakech on the details required for implementing the Kyoto Protocol, entry into force in 2003 is now a possibility. This paper assesses the potential macroeconomic impacts of the Kyoto Protocol, given the recent negotiated developments. In addition, given the recent attempts in the literature to model endogenous technical change in general equilibrium models, a new methodology for incorporating the induced innovations hypothesis into a general equilibrium model is described and implemented. In line with previous work, it is found that incorporation of the hypothesis reduces abatement costs. JF - Energy Economics AU - Jakeman, G AU - Hanslow, K AU - Hinchy, M AU - Fisher, B S AU - Woffenden, K AD - Australian Bureau of Agricultural and Resource Economics, G.P.O. Box 1563, Canberra, ACT 2601, Australia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 937 EP - 960 VL - 26 IS - 6 SN - 0140-9883, 0140-9883 KW - Pollution Abstracts; Sustainability Science Abstracts KW - International cooperation KW - Economics KW - Climatic changes KW - Air pollution control KW - Emission control KW - Greenhouse gases KW - Kyoto Protocol KW - International agreements KW - P 9000:ENVIRONMENTAL ACTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20523386?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Energy+Economics&rft.atitle=Induced+innovations+and+climate+change+policy&rft.au=Jakeman%2C+G%3BHanslow%2C+K%3BHinchy%2C+M%3BFisher%2C+B+S%3BWoffenden%2C+K&rft.aulast=Jakeman&rft.aufirst=G&rft.date=2004-11-01&rft.volume=26&rft.issue=6&rft.spage=937&rft.isbn=&rft.btitle=&rft.title=Energy+Economics&rft.issn=01409883&rft_id=info:doi/10.1016%2Fj.eneco.2004.09.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-04-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - International cooperation; Climatic changes; Economics; Emission control; Air pollution control; Greenhouse gases; International agreements; Kyoto Protocol DO - http://dx.doi.org/10.1016/j.eneco.2004.09.002 ER - TY - JOUR T1 - Annual Scientific Meeting of ASCEPT 2003: ENZYMATIC BIOREMEDIATION: FROM ENZYME DISCOVERY TO APPLICATIONS AN - 19431572; 6229407 AB - 1. Enzymatic bioremediation is potentially a rapid method of removing environmental pesticide residues. Applications include the treatment of residues resulting from agricultural production and processing industries, such as the treatment of irrigation waters, surface-contaminated fruit and vegetables and spent dip liquors. 2. A specific application for some organophosphate-degrading enzymes involves detoxification of nerve agent stockpiles. Effective and affordable remediation requires highly specialized enzymes, so protein engineering techniques are being used to improve properties of various source enzymes to enhance catalytic rates, stability and substrate range. 3. Trials with an optimized organophosphate-degrading enzyme have shown the feasibility of such technology in various applications. 4. The enzymes developed for environmental remediation for specific pesticide classes also have applications as antidotes for high-dose pesticide poisonings and as prophylaxis for people at risk of high pesticide doses. JF - Clinical and Experimental Pharmacology and Physiology AU - Sutherland, T D AU - Horne, I AU - Weir, K M AU - Coppin, C W AU - Williams, M R AU - Selleck, M AU - Russell, R J AU - Oakeshott, JG AD - Tara Sutherland, CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia, Tara.Sutherland@csiro.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 817 EP - 821 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 31 IS - 11 SN - 0305-1870, 0305-1870 KW - Biotechnology and Bioengineering Abstracts KW - Detoxification KW - nerve agents KW - Fruits KW - Vegetables KW - Bioremediation KW - Protein engineering KW - Pesticide residues KW - Irrigation KW - Poisoning KW - Enzymes KW - Clinical trials KW - Risk factors KW - Pesticides KW - Prophylaxis KW - Antidotes KW - W 30950:Waste Treatment & Pollution Clean-up UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19431572?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Human+Prenatal+and+Postnatal+Exposure+to+Polybrominated+Diphenyl+Ethers%2C+Polychlorinated+Biphenyls%2C+Polychlorobiphenylols%2C+and+Pentachlorophenol&rft.au=Guvenius%2C+Daiva+Meironyte%3BAronsson%2C+Anette%3BEkman-Ordeberg%2C+Gunvor%3BBergman%2C+Ake%3BNoren%2C+Koidu&rft.aulast=Guvenius&rft.aufirst=Daiva&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1235&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-01-01 N1 - SuppNotes - Figures, 2; tables, 2; references, 34. N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - nerve agents; Detoxification; Fruits; Vegetables; Bioremediation; Protein engineering; Pesticide residues; Irrigation; Poisoning; Enzymes; Clinical trials; Risk factors; Pesticides; Prophylaxis; Antidotes DO - http://dx.doi.org/10.1111/j.1440-1681.2004.04088.x ER - TY - JOUR T1 - Rural and urban traffic fatalities, vehicle miles, and population density AN - 18033086; 6005727 AB - The purpose of this study was to evaluate the effect of population density on the rates of motor vehicle mortality in rural and urban areas, while controlling for vehicle miles traveled (VMT). Rural and urban data for traffic mortality, VMT, and population were obtained for each state from the Federal Highway Administration for 1998-2000. Linear regression was used to estimate the effect of population density, VMT per capita, southern location, and presence of a trauma system on mortality. Variation in rural mortality rate (per 100, 000 population) was proportional to rural VMT per capita, but population density and southern location were also independent predictors, together accounting for 91% of this variation. Variation in urban mortality rates was not affected by population density, but urban rates were also higher in the south. The exposure- based rural mortality rate (deaths per 100 million VMT) was inversely proportional to population density, which along with southern location explained 41% of the variation from state to state. The presence of a state trauma system did not measurably affect mortality. After controlling for VMT and southern location, state population density was a moderately strong predictor of rural but not urban traffic mortality rates. JF - Accident Analysis & Prevention AU - Clark, DE AU - Cushing, B M AD - Department of Surgery, Maine Medical Center, 887 Congress Street, Suite 210, Portland, ME 04102, USA, clarkd@mmc.org Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 967 EP - 972 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 36 IS - 6 SN - 0001-4575, 0001-4575 KW - Health & Safety Science Abstracts KW - Mortality KW - Motor vehicles KW - Population density KW - Accidents KW - Traffic safety KW - Urban areas KW - Rural areas KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18033086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Accident+Analysis+%26+Prevention&rft.atitle=Rural+and+urban+traffic+fatalities%2C+vehicle+miles%2C+and+population+density&rft.au=Clark%2C+DE%3BCushing%2C+B+M&rft.aulast=Clark&rft.aufirst=DE&rft.date=2004-11-01&rft.volume=36&rft.issue=6&rft.spage=967&rft.isbn=&rft.btitle=&rft.title=Accident+Analysis+%26+Prevention&rft.issn=00014575&rft_id=info:doi/10.1016%2Fj.aap.2003.10.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Population density; Rural areas; Urban areas; Mortality; Motor vehicles; Traffic safety; Accidents DO - http://dx.doi.org/10.1016/j.aap.2003.10.006 ER - TY - JOUR T1 - Efficient plant regeneration from suspension cells of Allium cepa L. AN - 17873009; 6283023 AB - Plant regeneration from calli of three cultivars of Allium cepa (Senshuki, O.Pki and Shojovaka) was investigated. Callus was induced on four variations of BDS medium containing different concentrations of 2,4-dichlorophenoxyacetic acid (2,4-D) and 6-benzyladenine (BAP). The regeneration frequency of calli of cvs. Senshuki and O.Pki subcultured on solid MS medium supplemented with BAP ranged from 50% to 80%; this frequency decreased to less than 30% after subculture in the dark in liquid BDS medium. By repeating the dark/light transitions of the culture protocol and by selecting for green cell clusters, we were able to increase the regeneration frequency to more than 80% in all three cultivars. These cell clusters maintained a high regeneration capacity in subsequent subcultures in the absence of light for 2 months. Most (97%) of the regenerated plantlets had a normal diploid karyotype (2n=16) that was identical to that of the mother plants, although 3% of the regenerated plants of cv. Shojovaka had a tetraploid karyotype. JF - Plant Cell Reports AU - Zhang, Wenbo AU - Lin, Xiaofei AU - Takano, Hiroyoshi AU - Takio, Susumu AU - Ono, Kanji AD - Kumamoto University, Kurokami, Kumamoto, 860-8555, Japan, stakio@gpo.kumamoto-u.ac.jp Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 371 EP - 376 PB - Springer-Verlag (Berlin), Heidelberger Platz 3 Berlin 14197 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 23 IS - 6 SN - 0721-7714, 0721-7714 KW - Onion KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - 2,4-D KW - Plantlets KW - Diploids KW - Regeneration KW - Allium cepa KW - Subculture KW - Callus KW - Cell culture KW - Karyotypes KW - Light effects KW - W 30965:Miscellaneous, Reviews KW - W2 32220:Cell culture UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17873009?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Cell+Reports&rft.atitle=Efficient+plant+regeneration+from+suspension+cells+of+Allium+cepa+L.&rft.au=Zhang%2C+Wenbo%3BLin%2C+Xiaofei%3BTakano%2C+Hiroyoshi%3BTakio%2C+Susumu%3BOno%2C+Kanji&rft.aulast=Zhang&rft.aufirst=Wenbo&rft.date=2004-11-01&rft.volume=23&rft.issue=6&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Plant+Cell+Reports&rft.issn=07217714&rft_id=info:doi/10.1007%2Fs00299-004-0839-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Allium cepa; Plantlets; Karyotypes; Subculture; Light effects; Cell culture; 2,4-D; Diploids; Callus; Regeneration DO - http://dx.doi.org/10.1007/s00299-004-0839-2 ER - TY - JOUR T1 - Completeness and timeliness of treatment for chlamydia within a sexual health service AN - 17855253; 6146127 AB - Prompt treatment of genital Chlamydia trachomatis infection will reduce the duration of infectiousness and further transmission of infection. In 2002, an audit was conducted to assess the completeness and timeliness of treatment for uncomplicated chlamydial infection at the Sydney Sexual Health Centre, Australia. Over a nine-month period, chlamydia was diagnosed in 250 patients, 97% of whom received appropriate treatment. The median duration between initial attendance and treatment was two days. Prompt delivery of treatment was facilitated by: initial treatment of patients likely to be chlamydia-infected; rapid availability of test results; urgent communication of positive test results; and effective procedures for recalling untreated patients. JF - International Journal of STD & AIDS AU - Chen, MY AU - Ryder, N AU - Donovan, B AD - Sydney Sexual Health Centre, Sydney Hospital, GPO Box 1614, Sydney, New South Wales 2001, Australia, chenm@sesahs.nsw.gov.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 762 EP - 764 VL - 15 IS - 11 SN - 0956-4624, 0956-4624 KW - Microbiology Abstracts B: Bacteriology KW - Communication KW - Chlamydia trachomatis KW - Infection KW - J 02849:Sexually-transmitted diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17855253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Completeness+and+timeliness+of+treatment+for+chlamydia+within+a+sexual+health+service&rft.au=Chen%2C+MY%3BRyder%2C+N%3BDonovan%2C+B&rft.aulast=Chen&rft.aufirst=MY&rft.date=2004-11-01&rft.volume=15&rft.issue=11&rft.spage=762&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Communication; Infection; Chlamydia trachomatis ER - TY - JOUR T1 - Immunity to vacuolar pathogens: What can we learn from Legionella? AN - 17813173; 6218448 AB - Intracellular pathogens can manipulate host cellular pathways to create specialized organelles. These pathogen-modified vacuoles permit the survival and replication of bacterial and protozoan microorganisms inside of the host cell. By establishing an atypical organelle, intracellular pathogens present unique challenges to the host immune system. To understand pathogenesis, it is important to not only investigate how these organisms create unique subcellular compartments, but to also determine how mammalian immune systems have evolved to detect and respond to pathogens sequestered in specialized vacuoles. Recent studies have identified genes in the respiratory pathogen Legionella pneumophila that are essential for establishing a unique endoplasmic reticulum-derived organelle inside of mammalian macrophages, making this pathogen an attractive model system for investigations on host immune responses that are specific for bacteria that establish vacuoles disconnected from the endocytic pathway. This review will focus on the host immune response to Legionella and highlight areas of Legionella research that should help elucidate host strategies to combat infections by intracellular pathogens. JF - Cellular Microbiology AU - Neild, Annie L AU - Roy, Craig R AD - Yale University School of Medicine, Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06536 USA, craig.roy@yale.edu Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1011 EP - 1018 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 6 IS - 11 SN - 1462-5814, 1462-5814 KW - Microbiology Abstracts B: Bacteriology KW - Macrophages KW - Cell survival KW - Respiratory tract diseases KW - Legionella pneumophila KW - Replication KW - Reviews KW - Immune system KW - Vacuoles KW - Immunity KW - Immune response KW - Pathogens KW - J 02833:Immune response and immune mechanisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17813173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cellular+Microbiology&rft.atitle=Immunity+to+vacuolar+pathogens%3A+What+can+we+learn+from+Legionella%3F&rft.au=Neild%2C+Annie+L%3BRoy%2C+Craig+R&rft.aulast=Neild&rft.aufirst=Annie&rft.date=2004-11-01&rft.volume=6&rft.issue=11&rft.spage=1011&rft.isbn=&rft.btitle=&rft.title=Cellular+Microbiology&rft.issn=14625814&rft_id=info:doi/10.1111%2Fj.1462-5822.2004.00450.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - SuppNotes - Figures, 1; references, 66. N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Legionella pneumophila; Pathogens; Respiratory tract diseases; Vacuoles; Immune system; Replication; Cell survival; Reviews; Immune response; Macrophages; Immunity DO - http://dx.doi.org/10.1111/j.1462-5822.2004.00450.x ER - TY - JOUR T1 - Effects of algal canopy clearance on plant, fish and macroinvertebrate communities on eastern Tasmanian reefs AN - 17760517; 6157629 AB - Changes in assemblages of plants, macroinvertebrates and fishes on three eastern Tasmanian reefs were monitored over 12 months in replicated control blocks and adjacent 10x12-m blocks cleared of fucoid, laminarian and dictyotalean algae. Removal of canopy-forming plants produced less change to biotic assemblages than reported in studies elsewhere, with the magnitude of change for fish and invertebrate taxa lower than variation between sites and comparable to variation between months. The introduced annual kelp Undaria pinnatifida exhibited the only pronounced response to canopy removal amongst algal taxa, with a fivefold increase in cleared blocks compared to control blocks. Marine reserves are suggested to assist reef communities resist invasion by U. pinnatifida, through an indirect mechanism involving increased predation pressure on sea urchins and reduced formation of urchin barrens that are amenable to U. pinnatifida propagation. Large invertebrates were more associated with turfing algae or the reef substratum than the macroalgal canopy. The herbivorous sea urchin Heliocidaris erythrogramma and abalone Haliotis ruber showed the strongest response to clearing amongst common macroinvertebrate species, with a halving of population numbers. Observed densities of the common monacanthid fish Acanthaluteres vittiger also declined by about 50%. The relatively high level of resistance shown by eastern Tasmanian reef biota to patch disturbance was attributed largely to high diversity and biomass of turfing macroalgae damping effects of canopy clearance. JF - Journal of Experimental Marine Biology and Ecology AU - Edgar, G J AU - Barrett, N S AU - Morton, A J AU - Samson, C R AD - Zoology Department, Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, GPO Box 252-05, Hobart, Tasmania 7001, Australia, g.edgar@utas.edu.au Y1 - 2004/11// PY - 2004 DA - November 2004 SP - 67 EP - 87 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 312 IS - 1 SN - 0022-0981, 0022-0981 KW - Abalone KW - ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; Ecology Abstracts KW - Algal canopy KW - Experimental clearance KW - Invertebrate KW - Marine protected area KW - Sublittoral KW - Turbo undulatus KW - Undaria pinnatifida KW - Urchin barrens KW - Reefs KW - Predation KW - Population density KW - Kelps KW - Interspecific relationships KW - Acanthaluteres vittiger KW - Canopies KW - Marine KW - Heliocidaris erythrogramma KW - Community composition KW - Species diversity KW - Marine parks KW - Zoobenthos KW - Haliotis ruber KW - Damping KW - Population number KW - O 1070:Ecology/Community Studies KW - Q1 08483:Species interactions: general KW - D 04330:Marine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17760517?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Inhalation+Exposure+of+Rats+to+Asphalt+Fumes+Generated+at+Paving+Temperatures+Alters+Pulmonary+Xenobiotic+Metabolism+Pathways+Without+Lung+Injury&rft.au=Ma%2C+Jane+YC%3BRengasamy%2C+Apavoo%3BFrazer%2C+Dave%3BBarger%2C+Mark+W%3BHubbs%2C+Ann+F%3BBattelli%2C+Lori%3BTomblyn%2C+Seith&rft.aulast=Ma&rft.aufirst=Jane&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1215&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Reefs; Community composition; Interspecific relationships; Species diversity; Predation; Population density; Marine parks; Canopies; Kelps; Zoobenthos; Population number; Damping; Turbo undulatus; Heliocidaris erythrogramma; Acanthaluteres vittiger; Haliotis ruber; Undaria pinnatifida; Marine DO - http://dx.doi.org/10.1016/j.jembe.2004.06.005 ER - TY - JOUR T1 - Drainage morphometry and its influence on landform characteristics in a basaltic terrain, Central India-a remote sensing and GIS approach AN - 17699606; 6047018 AB - An attempt has been made to study drainage morphometry and its influence on landform processes, soil physical and land erosion characteristics in Vena river basin of basaltic terrain (Deccan traps), Nagpur district, Maharashtra, Central India. High Spatial Resolution Indian Remote Sensing Satellite (IRS)-ID Linear Image Self Scanning (LISS)-III sensor data of 7 March 2000 in conjunction with Survey Of India (SOI) topographical sheets (1:50, 000 scale) were used for systematic analysis of various morphometric, lithological and landform characteristics of the river basin. Morphometric analysis was carried out at sub basin level using Spatial Analysis System (SPANS ver. 7.0) GIS system to analyze the influence of drainage morphometry on landforms, soil depth, drainage, available water holding capacity (AWC) and land erosion characteristics. ten distinct landforms were identified in the basin based on visual interpretation of satellite sensor data. These are dissected ridges, isolated mounds, linear ridges, escarpments, plateau spurs, subdued plateau, rolling plains, foot slopes, narrow valleys and main valley floor. Very shallow soils exists on dissected ridges, isolated mounds, linear ridges, escarpments and plateau spurs covering the sub basins nos. 1, 5-7, 9, 15 and 16 and are associated with high drainage density (Dd), impermeable geology and high runoff conditions. High drainage density, high bifurcation ratio (Rb) and steep slopes are the main causative factors for the development of well-drained soils. The AWC is low in the soils of higher elevations covering the sub basins 1, 2, 3, 4, 7 and 9 whereas, it is very high at lower elevation in the sub basins nos. 12, 13 and 19. Sub basins nos. 1, 2, 5, 15 and 16, associated with high drainage density, stream frequency (Fu) and texture ratio (T) showed very severe to severe erosion. The analysis reveals that the influence of drainage morphometry is very significant in understanding the landform processes, soil physical properties and erosional characteristics. The study demonstrates that remotely sensed data and GIS based approach is found to be more appropriate than the conventional methods in evaluation and analysis of drainage morphometry, landforms and land resources and to understand their inter-relationships for planning and management at river basin level. JF - International Journal of Applied Earth Observation and Geoinformation AU - Reddy, GPO AU - Maji, A K AU - Gajbhiye, K S AD - National Bureau of Soil Survey and Land Use Planning, Amravati Road, Nagpur 440 010, India, obireddy@nbsslup.mah.nic.in Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1 EP - 16 PB - Elsevier Science Inc., Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.com] VL - 6 IS - 1 SN - 1569-8432, 1569-8432 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - SW 0835:Streamflow and runoff KW - Q2 02171:Dynamics of lakes and rivers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17699606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Applied+Earth+Observation+and+Geoinformation&rft.atitle=Drainage+morphometry+and+its+influence+on+landform+characteristics+in+a+basaltic+terrain%2C+Central+India-a+remote+sensing+and+GIS+approach&rft.au=Reddy%2C+GPO%3BMaji%2C+A+K%3BGajbhiye%2C+K+S&rft.aulast=Reddy&rft.aufirst=GPO&rft.date=2004-11-01&rft.volume=6&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Applied+Earth+Observation+and+Geoinformation&rft.issn=15698432&rft_id=info:doi/10.1016%2Fj.jag.2004.06.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.jag.2004.06.003 ER - TY - JOUR T1 - REPORT: Ecological risk assessment of transgenic pasture plants: a community gradient modelling approach AN - 17610429; 6225917 AB - The extension of transgene technology to pasture species presents new challenges for ecological risk assessment because, unlike most crops, pasture plants are well adapted for persistence in mixed plant communities and are an important source of invasive species worldwide. Despite this, the impact of transgenic pasture plants on native ecosystems remains relatively unstudied. Here we use a community gradient modelling approach to investigate the performance of subterranean clover containing a nutrition-enhancing transgene over a range of ecologically important grassland communities at a study site in south-eastern Australia. Our data, which were collected over a full annual growing season, show that the transgenic clover line has different seedling survival and seed dormancy breakdown rates than the commercial non-transgenic line, which suggests that transgenic populations will decline faster than non-transgenic ones in perennial native grassland communities but could, under optimal climatic conditions, have potentially higher growth rates in grazed annual grasslands. These results demonstrate that changes to ecologically important demographic parameters can occur in plants containing transgenes that are not typically considered fitness enhancing, and that genotype by environment interactions and management regimes that impact on these parameters may influence the invasiveness of transgenic plants. Our study also demonstrates the utility of incorporating plant community gradient modelling into ecological risk assessment protocols designed for transgenic pasture plants. JF - Ecology Letters AU - Godfree, Robert C AU - Young, Andrew G AU - Lonsdale, WMark AU - Woods, Matthew J AU - Burdon, Jeremy J AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, robert.godfree@csiro.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1077 EP - 1089 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 7 IS - 11 SN - 1461-023X, 1461-023X KW - Ecology Abstracts; Sustainability Science Abstracts KW - M3 1010:Issues in Sustainable Development KW - D 04110:Grasslands UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17610429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecology+Letters&rft.atitle=REPORT%3A+Ecological+risk+assessment+of+transgenic+pasture+plants%3A+a+community+gradient+modelling+approach&rft.au=Godfree%2C+Robert+C%3BYoung%2C+Andrew+G%3BLonsdale%2C+WMark%3BWoods%2C+Matthew+J%3BBurdon%2C+Jeremy+J&rft.aulast=Godfree&rft.aufirst=Robert&rft.date=2004-11-01&rft.volume=7&rft.issue=11&rft.spage=1077&rft.isbn=&rft.btitle=&rft.title=Ecology+Letters&rft.issn=1461023X&rft_id=info:doi/10.1111%2Fj.1461-0248.2004.00664.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - SuppNotes - Figures, 3; tables, 2. N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1111/j.1461-0248.2004.00664.x ER - TY - JOUR T1 - Influence of damping systems on building structures subject to seismic effects AN - 17531978; 6094877 AB - This paper investigates the response of multi-storey structures under simulated earthquake loads with friction dampers, viscoelastic dampers and combined friction-viscoelastic damping devices strategically located within shear walls. Consequently, evaluations are made as to how the damping systems affect the seismic response of these structures with respect to deflections and accelerations. In particular, this paper concentrates on the effects of damper types, configurations and their locations within the cut-outs of shear walls. The initial stiffness of the cut out section of the shear wall is removed and replaced by the stiffness and damping of the device. Influence of parameters of damper properties such as stiffness, damping coefficient, location, configuration and size are studied and evaluated using results obtained under several different earthquake scenarios. Structural models with cut outs at different heights are treated in order to establish the effectiveness of the dampers and their optimal placement. This conceptual study has demonstrated the feasibility of mitigating the seismic response of building structures by using embedded dampers. JF - Engineering Structures AU - Marko, J AU - Thambiratnam, D AU - Perera, N AD - School of Civil Engineering, Physical Infrastructure Center, Queensland University of Technology, GPO Box 2434, 2 George Street, Brisbane, Qld 4001, Australia, d.thambiratnam@qut.edu.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1939 EP - 1956 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 26 IS - 13 SN - 0141-0296, 0141-0296 KW - dampers KW - Health & Safety Science Abstracts KW - Earthquakes KW - Structural analysis KW - Seismic activity KW - H 15000:Civil/Structural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17531978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Engineering+Structures&rft.atitle=Influence+of+damping+systems+on+building+structures+subject+to+seismic+effects&rft.au=Marko%2C+J%3BThambiratnam%2C+D%3BPerera%2C+N&rft.aulast=Marko&rft.aufirst=J&rft.date=2004-11-01&rft.volume=26&rft.issue=13&rft.spage=1939&rft.isbn=&rft.btitle=&rft.title=Engineering+Structures&rft.issn=01410296&rft_id=info:doi/10.1016%2Fj.engstruct.2004.07.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Earthquakes; Seismic activity; Structural analysis DO - http://dx.doi.org/10.1016/j.engstruct.2004.07.008 ER - TY - JOUR T1 - Evaluation of Dendritic Gadolinium Complexes as MRI Contrast Agents AN - 17485432; 6110894 AB - A series of dendritic gadolinium complexes based on dendrimers with 1,4,7,10-tetraazacyclododecane as the core were synthesized. Both diethylenetriaminepentaacetic acid and pyridoxamine were incorporated to the amine groups on the surface to give the dendritic ligands. These dendritic ligands were then reacted with gadolinium chloride to yield the corresponding dendritic gadolinium complexes. The dendritic ligands and their gadolinium complexes were characterized by super(1)HNMR, IR, UV and elemental analysis. Relaxivity studies showed that the dendritic gadolinium complexes have higher relaxation effectiveness than that of the clinically used small molecular gadolinium complexes. Magnetic resonance imaging of the liver in rats indicated that the dendritic gadolinium complex containing pyridoxamine enhances the image contrast of the liver, provides prolonged intravascular duration and produces highly contrasted visualization of blood vessels in the liver. JF - Journal of Bioactive and Compatible Polymers AU - Yan, Guo-Ping AU - Bottle, SE AU - Zhuo, Ren-Xi AU - Wei, Li AU - Liu, Mai-Li AU - Li, Li-Yun AD - School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Q4001, Australia, guopyan@hotmail.com Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 453 EP - 465 VL - 19 IS - 6 SN - 0883-9115, 0883-9115 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - amines KW - Blood vessels KW - Magnetic resonance imaging KW - Gadolinium KW - Contrast media KW - Liver KW - Chloride KW - W4 150:Medical Imaging KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17485432?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Bioactive+and+Compatible+Polymers&rft.atitle=Evaluation+of+Dendritic+Gadolinium+Complexes+as+MRI+Contrast+Agents&rft.au=Yan%2C+Guo-Ping%3BBottle%2C+SE%3BZhuo%2C+Ren-Xi%3BWei%2C+Li%3BLiu%2C+Mai-Li%3BLi%2C+Li-Yun&rft.aulast=Yan&rft.aufirst=Guo-Ping&rft.date=2004-11-01&rft.volume=19&rft.issue=6&rft.spage=453&rft.isbn=&rft.btitle=&rft.title=Journal+of+Bioactive+and+Compatible+Polymers&rft.issn=08839115&rft_id=info:doi/10.1177%2F0883911504048375 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Gadolinium; Liver; Magnetic resonance imaging; amines; Blood vessels; Contrast media; Chloride DO - http://dx.doi.org/10.1177/0883911504048375 ER - TY - JOUR T1 - Breeding for high water-use efficiency AN - 17289428; 6062175 AB - There is a pressing need to improve the water-use efficiency of rain-fed and irrigated crop production. Breeding crop varieties with higher water-use efficiency is seen as providing part of the solution. Three key processes can be exploited in breeding for high water-use efficiency: (i) moving more of the available water through the crop rather than it being wasted as evaporation from the soil surface or drainage beyond the root zone or being left behind in the root zone at harvest; (ii) acquiring more carbon (biomass) in exchange for the water transpired by the crop, i.e. improving crop transpiration efficiency; (iii) partitioning more of the achieved biomass into the harvested product. The relative importance of any one of these processes will vary depending on how water availability varies during the crop cycle. However, these three processes are not independent. Targeting specific traits to improve one process may have detrimental effects on the other two, but there may also be positive interactions. Progress in breeding for improved water-use efficiency of rain-fed wheat is reviewed to illustrate the nature of some of these interactions and to highlight opportunities that may be exploited in other crops as well as potential pitfalls. For C sub(3) species, measuring carbon isotope discrimination provides a powerful means of improving water-use efficiency of leaf gas exchange, but experience has shown that improvements in leaf-level water-use efficiency may not always translate into higher crop water-use efficiency or yield. In fact, the reverse has frequently been observed. Reasons for this are explored in some detail. Crop simulation modelling can be used to assess the likely impact on water-use efficiency and yield of changing the expression of traits of interest. Results of such simulations indicate that greater progress may be achieved by pyramiding traits so that potential negative effects of individual traits are neutralized. DNA-based selection techniques may assist in such a strategy. JF - Journal of Experimental Botany AU - Condon, A G AU - Richards, R A AU - Rebetzke, G J AU - Farquhar, G D AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 2447 EP - 2460 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 55 IS - 407 SN - 0022-0957, 0022-0957 KW - Wheat KW - Water Resources Abstracts; Genetics Abstracts KW - G 07349:General KW - SW 1060:Conservation in agricultural use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17289428?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Botany&rft.atitle=Breeding+for+high+water-use+efficiency&rft.au=Condon%2C+A+G%3BRichards%2C+R+A%3BRebetzke%2C+G+J%3BFarquhar%2C+G+D&rft.aulast=Condon&rft.aufirst=A&rft.date=2004-11-01&rft.volume=55&rft.issue=407&rft.spage=2447&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Botany&rft.issn=00220957&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Prediction of Toxicant-Specific Gene Expression Signatures After Chemotherapeutic Treatment of Breast Cell Lines AN - 14719739; 10672636 AB - Results are presented from a study in which a panel of treated breast cell lines was used to identify toxicant-specific signatures for the chemotherapeutics, doxorubicin (DOX) and 5-fluorouracil (5FU). The results show that the cell lines exhibited distinct toxicant-specific patterns of response. Using two statistical methods for class prediction, sets of genes were identified that distinguished DOX- and 5FU-treated cells, which were used to predict the mechanism of etoposide, a drug that is mechanistically similar to DOX. Computational analyses were used to demonstrate that distinct transcriptional patterns could be identified for mechanistically dissimilar compounds and that toxicants with similar mechanisms could be classified accordingly. JF - Environmental Health Perspectives AU - Troester, Melissa A AU - Hoadley, Katherine A AU - Parker, Joel S AU - Perou, Charles M Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1607 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - TOXIC SUBSTANCES KW - DRUGS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14719739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prediction+of+Toxicant-Specific+Gene+Expression+Signatures+After+Chemotherapeutic+Treatment+of+Breast+Cell+Lines&rft.au=Troester%2C+Melissa+A%3BHoadley%2C+Katherine+A%3BParker%2C+Joel+S%3BPerou%2C+Charles+M&rft.aulast=Troester&rft.aufirst=Melissa&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1607&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - TOXIC SUBSTANCES; DRUGS; GENETICS, HUMAN ER - TY - JOUR T1 - Effects of 1,3-Butadiene, Isoprene, and Their Photochemical Degradation Products on Human Lung Cells AN - 14718288; 10672452 AB - Human lung epithelial cells were interfaced with a smog chamber to assess the toxicity of 1,3-butadiene, isoprene, and their photochemical degradation products. The photochemical products of both compounds were found to increase lactate dehydrogenase release, as well as interleukin-8 expression, compared with clean-air controls, and the photochemical products were more potent inducers of interleukin-8 gene expression than the unreacted VOCs. Exposure to the parent compounds generated significant levels of cytotoxicity and interleukin-8 expression in A549 cells, but no significant effects were observed in differentiated human bronchial epithelial cells, which possibly represented regional differences in sensitivity within the respiratory epithelium. The main isoprene first-generation photochemical products formed were methacrolein, methyl vinyl ketone, formaldehyde, and ozone, while those formed from 1,3-butadiene included acrolein, formaldehyde, and O sub(3). JF - Environmental Health Perspectives AU - Doyle, Melanie AU - Sexton, Kenneth G AU - Jeffries, Harvey AU - Bridge, Kevin AU - Jaspers, Ilona Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1488 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CYTOTOXICITY KW - BUTADIENE KW - PROTEIN SYNTHESIS KW - VOLATILE ORGANIC COMPOUNDS KW - PULMONARY EFFECTS KW - PHOTOCHEMISTRY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718288?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+1%2C3-Butadiene%2C+Isoprene%2C+and+Their+Photochemical+Degradation+Products+on+Human+Lung+Cells&rft.au=Doyle%2C+Melanie%3BSexton%2C+Kenneth+G%3BJeffries%2C+Harvey%3BBridge%2C+Kevin%3BJaspers%2C+Ilona&rft.aulast=Doyle&rft.aufirst=Melanie&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1488&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CYTOTOXICITY; BUTADIENE; PROTEIN SYNTHESIS; PULMONARY EFFECTS; PHOTOCHEMISTRY; VOLATILE ORGANIC COMPOUNDS ER - TY - JOUR T1 - Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: a CaseControl Study in Newborn Boys AN - 14717166; 10672464 AB - Cryptorchidism, which is the maldescent of the testis, and hypospadias, which is the abnormal location of the orifice of the urethra, are among the most frequent congenital abnormalities in male births. In this study, the role of maternal and paternal occupational and dietary exposures to potential endocrine disruptors in the occurrences of the syndromes was investigated using a nested casecontrol strategy in Rotterdam, Netherlands. Parents were interviewed using a structured questionnaire to ascertain lifestyle and demographic data, as well as possible risk factors related to occupation and diet. Significant risk factors were found to be related to intrauterine growth, as well as to smoking among fathers and paternal self-reported exposure to pesticides and solvents. Multivariate analysis revealed that the important risk factors for hypospadias were small for gestational age at birth and the health status of the mother, while paternal smoking and pesticide exposure were associated significantly with cryptorchidism. JF - Environmental Health Perspectives AU - Pierik, Frank H AU - Burdorf, Alex AU - Deddens, James A AU - Juttmann, Rikard E AU - Weber, Rob FA Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1570 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HORMONAL EFFECTS KW - CIGARETTE SMOKE KW - DIET KW - RISK ASSESSMENT KW - NETHERLANDS KW - BIRTH DEFECTS, HUMAN KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14717166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Maternal+and+Paternal+Risk+Factors+for+Cryptorchidism+and+Hypospadias%3A+a+Case%26lt%3BND%26gt%3BControl+Study+in+Newborn+Boys&rft.au=Pierik%2C+Frank+H%3BBurdorf%2C+Alex%3BDeddens%2C+James+A%3BJuttmann%2C+Rikard+E%3BWeber%2C+Rob+FA&rft.aulast=Pierik&rft.aufirst=Frank&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1570&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; NETHERLANDS; HORMONAL EFFECTS; DIET; CIGARETTE SMOKE; BIRTH DEFECTS, HUMAN; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Relationship Between Composition and Toxicity of Motor Vehicle Emission Samples AN - 14717032; 10672458 JF - Environmental Health Perspectives AU - McDonald, Jacob D AU - Eide, Ingvar AU - Seagrave, JeanClare AU - Zielinska, Barbara AU - Whitney, Kevin AU - Lawson, Douglas R AU - Mauderly, Joe L Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1527 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - QUANTITATIVE ANALYSIS KW - AUTOMOBILE EMISSIONS KW - PARTICULATES KW - TOXICOLOGY KW - MUTAGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14717032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Relationship+Between+Composition+and+Toxicity+of+Motor+Vehicle+Emission+Samples&rft.au=McDonald%2C+Jacob+D%3BEide%2C+Ingvar%3BSeagrave%2C+JeanClare%3BZielinska%2C+Barbara%3BWhitney%2C+Kevin%3BLawson%2C+Douglas+R%3BMauderly%2C+Joe+L&rft.aulast=McDonald&rft.aufirst=Jacob&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1527&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; QUANTITATIVE ANALYSIS; AUTOMOBILE EMISSIONS; MUTAGENIC AGENTS; TOXICOLOGY; PARTICULATES ER - TY - JOUR T1 - Impact of the Phytoestrogen Content of Laboratory Animal Feed on the Gene Expression Profile of the Reproductive System in the Immature Female Rat AN - 14716933; 10672457 AB - Gene expression profiling was used to evaluate the effects of two diets with different phytoestrogen contents on the transcript profile of the uterus and ovaries in prepubertal SpragueDawley rats. One group was fed the standard laboratory rodent diet, Purina 5001, and the other was maintained on a casein-based diet. The standard diet contained phytoestrogens, mostly genistein and daidzein, while the casein-based diet was essentially phytoestrogen-free. One subgroup from each diet was dosed with 0.1 mu g/kg/d 17 alpha -ethylnylestradiol (EE) in peanut oil. No differences between groups were found in terms of body weight or uterine weight, and no clinical signs of toxicity were noted. Expression was found to be significantly different in 29 genes, however, although the response to the diet's composition was independent from the EE effect. JF - Environmental Health Perspectives AU - Naciff, Jorge M AU - Overmann, Gary J AU - Torontali, Suzanne M AU - Carr, Gregory J AU - Tiesman, Jay P AU - Daston, George P Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1519 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - HORMONAL EFFECTS KW - DIET KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Impact+of+the+Phytoestrogen+Content+of+Laboratory+Animal+Feed+on+the+Gene+Expression+Profile+of+the+Reproductive+System+in+the+Immature+Female+Rat&rft.au=Naciff%2C+Jorge+M%3BOvermann%2C+Gary+J%3BTorontali%2C+Suzanne+M%3BCarr%2C+Gregory+J%3BTiesman%2C+Jay+P%3BDaston%2C+George+P&rft.aulast=Naciff&rft.aufirst=Jorge&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1519&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t photos N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; HORMONAL EFFECTS; DIET; RODENTS ER - TY - JOUR T1 - Blood Lead Changes During Pregnancy and Postpartum with Calcium Supplementation AN - 14716126; 10672454 JF - Environmental Health Perspectives AU - Gulson, Brian L AU - Mizon, Karen J AU - Palmer, Jacqueline M AU - Korsch, Michael J AU - Taylor, Alan J AU - Mahaffey, Kathryn R Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1499 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CALCIUM KW - BLOOD LEAD LEVEL KW - PREGNANCY KW - FOOD SUPPLEMENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716126?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Blood+Lead+Changes+During+Pregnancy+and+Postpartum+with+Calcium+Supplementation&rft.au=Gulson%2C+Brian+L%3BMizon%2C+Karen+J%3BPalmer%2C+Jacqueline+M%3BKorsch%2C+Michael+J%3BTaylor%2C+Alan+J%3BMahaffey%2C+Kathryn+R&rft.aulast=Gulson&rft.aufirst=Brian&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1499&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CALCIUM; PREGNANCY; BLOOD LEAD LEVEL; FOOD SUPPLEMENTS ER - TY - JOUR T1 - Androgenic and Estrogenic Response of Green Mussel Extracts from Singapore's Coastal Environment Using a Human Cell-Based Bioassay AN - 14715863; 10672449 JF - Environmental Health Perspectives AU - Bayen, Stephane AU - Gong, Yinhan AU - Chin, Hong Soon AU - Lee, Hian Kee AU - Leong, Yong Eu AU - Obbard, Jeffrey Philip Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1467 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MUSSELS KW - SINGAPORE KW - HORMONAL EFFECTS KW - BIOASSAY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14715863?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Androgenic+and+Estrogenic+Response+of+Green+Mussel+Extracts+from+Singapore%27s+Coastal+Environment+Using+a+Human+Cell-Based+Bioassay&rft.au=Bayen%2C+Stephane%3BGong%2C+Yinhan%3BChin%2C+Hong+Soon%3BLee%2C+Hian+Kee%3BLeong%2C+Yong+Eu%3BObbard%2C+Jeffrey+Philip&rft.aulast=Bayen&rft.aufirst=Stephane&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1467&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MUSSELS; SINGAPORE; HORMONAL EFFECTS; BIOASSAY ER - TY - JOUR T1 - Understanding the Spatial Clustering of Severe Acute Respiratory Syndrome (SARS) in Hong Kong AN - 14715565; 10672461 AB - Geographic information system technology was applied to map and visualize the severe acute respiratory syndrome (SARS) outbreak in Hong Kong in late 2002 and early 2003. Data on SARS occurrence were derived from case-contact interviews that were text based. Three levels of geostatistical analysis were carried out: an elementary analysis involving simple visual inspection of a geographic phenomenon; a cluster analysis that attempted to identify possible hot spots; and a contextual analysis to explain relationships among geographic phenomena. Results demonstrated exceptional spatial clustering of the cases. The daily animated series of kernel maps showed clearly that SARS was a highly localized disease, such that its route of transmission was unlikely to be through casual contact. JF - Environmental Health Perspectives AU - Lai, P C AU - Wong, C M AU - Hedley, A J AU - Lo, S V AU - Leung, P Y AU - Kong, J AU - Leung, G M Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1550 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HONG KONG KW - GEOGRAPHIC INFORMATION SYSTEMS KW - RESPIRATORY DISORDERS KW - SPATIAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14715565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Understanding+the+Spatial+Clustering+of+Severe+Acute+Respiratory+Syndrome+%28SARS%29+in+Hong+Kong&rft.au=Lai%2C+P+C%3BWong%2C+C+M%3BHedley%2C+A+J%3BLo%2C+S+V%3BLeung%2C+P+Y%3BKong%2C+J%3BLeung%2C+G+M&rft.aulast=Lai&rft.aufirst=P&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1550&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 14 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HONG KONG; GEOGRAPHIC INFORMATION SYSTEMS; RESPIRATORY DISORDERS; SPATIAL COMPARISONS ER - TY - JOUR T1 - Geographic Analysis of Blood Lead Levels in New York State Children Born 19941997 AN - 14714949; 10672465 AB - Data obtained from the New York State Department of Health on the blood lead levels of children born in the state between 1994 and 1997 were analyzed using a geographic information system to assess the geographic occurrence of high blood Pb and to detect trends over time. Socioeconomic data were collected from several sources, and the combined data were examined using multiple linear regression and simultaneous autoregression. Results revealed that blood Pb levels varied widely across the state, and a large portion of the variation in the data was described by the age of housing, education level, and percentage of African-American births in a community. Surprisingly, no association was found with population density. The blood Pb levels declined by a dramatic 44% over the 4-yr period, which was attributed presumably to greater public awareness, the remediation and replacement of older homes, and the phase-out of leaded gasoline. JF - Environmental Health Perspectives AU - Haley, Valerie B AU - Talbot, Thomas O Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1577 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HOUSING KW - BLOOD LEAD LEVEL KW - AREA COMPARISONS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - NEW YORK STATE KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14714949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Geographic+Analysis+of+Blood+Lead+Levels+in+New+York+State+Children+Born+1994%26lt%3BND%26gt%3B1997&rft.au=Haley%2C+Valerie+B%3BTalbot%2C+Thomas+O&rft.aulast=Haley&rft.aufirst=Valerie&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1577&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AREA COMPARISONS; GEOGRAPHIC INFORMATION SYSTEMS; HOUSING; BLOOD LEAD LEVEL; NEW YORK STATE; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Cumulative Dietary Energy Intake Determines the Onset of Puberty in Female Rats AN - 14714299; 10672450 AB - The relationship between total energy intake and sexual maturation in female rats was investigated using two types of dietary modification. In one, infant formula at different concentrations and sugar solutions were used to modulate metabolic energy intake, and in the second, open-formula synthetic phytoestrogen-free diets with a wide range of metabolizable energies were evaluated. Increasing the metabolizable energy density of the synthetic diet proportionally increased body weight and total energy intake, and increasing energy intake was associated with an increase in uterine weight. The uterotrophic activities of the infant formula and the diets were abolished by co-administration of the gonadotrophin-releasing hormone antagonist, Antarelix, but the uterotrophic activity of diethylstilbestrol was unaffected. The mean day of vaginal opening was advanced by the high-metabolizable energy diets and infant formula, while the body weight at vaginal opening was unaffected. JF - Environmental Health Perspectives AU - Odum, Jenny AU - Tinwell, Helen AU - Tobin, Graham AU - Ashby, John Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1472 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - METABOLIC ACTIVATION KW - HORMONAL EFFECTS KW - DIET KW - NUTRITION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14714299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cumulative+Dietary+Energy+Intake+Determines+the+Onset+of+Puberty+in+Female+Rats&rft.au=Odum%2C+Jenny%3BTinwell%2C+Helen%3BTobin%2C+Graham%3BAshby%2C+John&rft.aulast=Odum&rft.aufirst=Jenny&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1472&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 12 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - METABOLIC ACTIVATION; HORMONAL EFFECTS; DIET; NUTRITION ER - TY - JOUR T1 - Evidence for Concurrent Effects of Exposure to Environmental Cadmium and Lead on Hepatic CYP2A6 Phenotype and Renal Function Biomarkers in Nonsmokers AN - 14713911; 10672456 AB - In a group of healthy men and women from Thailand who had never smoked, the relationships between phenotype of hepatic cytochrome P4502A6 (CYP2A6), nephropathy, and exposure to cadmium and lead were examined. Blood and urine samples were collected and analyzed. A positive correlation was found between Cd burden and age, which was stronger in men than in women, but body iron store status was not correlated with Cd burden in either sex. Women's urinary zinc excretion showed an inverse correlation with age, but no such correlation was noted in men. Men had 36% higher urinary Zn excretion together with higher Zn:Cd and Zn:Pb ratios than did women. A positive correlation was found between CYP2A6 activity and Cd burden in both men and women, which remained statistically significant after controlling for age. In men, a Pb-suppressive effect on liver CYP2A6 was observed, which was not observed in women. JF - Environmental Health Perspectives AU - Satarug, Soisungwan AU - Nishijo, Muneko AU - Ujjin, Pailin AU - Vanavanitkun, Yuvaree AU - Baker, Jason R AU - Moore, Michael R Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1512 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - PROTEIN SYNTHESIS KW - CADMIUM KW - ZINC KW - HEPATOTOXICITY KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713911?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Evidence+for+Concurrent+Effects+of+Exposure+to+Environmental+Cadmium+and+Lead+on+Hepatic+CYP2A6+Phenotype+and+Renal+Function+Biomarkers+in+Nonsmokers&rft.au=Satarug%2C+Soisungwan%3BNishijo%2C+Muneko%3BUjjin%2C+Pailin%3BVanavanitkun%2C+Yuvaree%3BBaker%2C+Jason+R%3BMoore%2C+Michael+R&rft.aulast=Satarug&rft.aufirst=Soisungwan&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1512&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; ZINC; HEPATOTOXICITY; PROTEIN SYNTHESIS; LEAD; CADMIUM ER - TY - JOUR T1 - Induced Sputum Assessment in New York City Firefighters Exposed to World Trade Center Dust AN - 14713654; 10672463 AB - The induced sputum (IS) methodology was used to assess respired particulate matter and the inflammatory response of the lung in New York City firefighters after exposure to dust from the World Trade Center following the terrorist attack in September 2001. Inflammation was assessed by differential cell counts and by measuring metalloproteinase-9, a cytokine involved in airways inflammation and remodeling. Particulate matter was assessed by size distribution, mineral composition, and by comparison to settled dust samples collected at the site. The firefighters were examined ten months after the World Trade Center collapse. Results showed that differential counts for neutrophils and eosinophils increased with cumulative World Trade Center workday exposure intensity. The levels of metalloproteinase-9 were correlated positively with the percentage of neutrophils and negatively with the percentage of macrophages. In the firefighter IS samples, a high load of relatively large particles with irregularly shaped structures was found, and the particles were consistent chemically and mineralogically with exposures to aerosolized building debris and dust and smoke generated by the collapse and fires. JF - Environmental Health Perspectives AU - Fireman, Elizabeth M AU - Lerman, Yehuda AU - Ganor, Eliezer AU - Greif, Joel AU - Fireman-Shoresh, Sharon AU - Lioy, Paul J AU - Banauch, Gisela I Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1564 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - AIR POLLUTION EFFECTS KW - NEW YORK CITY KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713654?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Induced+Sputum+Assessment+in+New+York+City+Firefighters+Exposed+to+World+Trade+Center+Dust&rft.au=Fireman%2C+Elizabeth+M%3BLerman%2C+Yehuda%3BGanor%2C+Eliezer%3BGreif%2C+Joel%3BFireman-Shoresh%2C+Sharon%3BLioy%2C+Paul+J%3BBanauch%2C+Gisela+I&rft.aulast=Fireman&rft.aufirst=Elizabeth&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1564&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; AIR POLLUTION EFFECTS; PARTICULATES; NEW YORK CITY ER - TY - JOUR T1 - Xenoestrogen-Induced ERK-1 and ERK-2 Activation via Multiple Membrane-Initiated Signaling Pathways AN - 14713632; 10672451 AB - Using the pituitary tumor cell line, GH sub(3)/B6/F10, the ability of selected estrogen mimetics to produce rapid activation of extracellular-regulated kinases (ERKs) via various signaling pathways was investigated. The compounds used included dieldrin, endosulfan, o,p' DDE, p-nonylphenol, bisphenol A, and the natural phytoestrogen, coumestrol. A fixed cell-based enzyme linked immunoassay was used to monitor signaling events leading to ERK activation. All of the compounds, except for bisphenol A, elicited rapid membrane-initiated actions at very low concentrations compared with their reported potencies in classical genomic pathways. All active compounds were able to produce rapid ERK phosphorylations in the nanomolar concentration range, while coumestrol, nonylphenol, and endosulfan were also active in the subpicomolar range. Inhibitors that have been found to pinpoint various mechanisms leading to ERK phosphorylation differently affected each xenoestrogen response examined. JF - Environmental Health Perspectives AU - Bulayeva, Nataliya N AU - Watson, Cheryl S Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1481 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSE RESPONSE PROFILES KW - HORMONAL EFFECTS KW - DETERGENTS AND SOAPS KW - ORGANOCHLORINE PESTICIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713632?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Xenoestrogen-Induced+ERK-1+and+ERK-2+Activation+via+Multiple+Membrane-Initiated+Signaling+Pathways&rft.au=Bulayeva%2C+Nataliya+N%3BWatson%2C+Cheryl+S&rft.aulast=Bulayeva&rft.aufirst=Nataliya&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1481&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 19 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; HORMONAL EFFECTS; DETERGENTS AND SOAPS; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Growth responses, physiology and decay associated with pruning plantation-grown Eucalyptus globulus Labill. and E. nitens (Deane and Maiden) Maiden AN - 17763908; 6144416 AB - Detailed studies have been undertaken to define pruning regimes for Eucalyptus nitens, but little is known of E. globulus responses to pruning although this is a more commonly planted species. This paper describes experiments that aimed to identify (a) levels of pruning that reduce E. globulus growth, (b) physiological processes contributing to those growth responses, (c) the incidence of decay and factors influencing decay incidence following pruning of E. globulus, and (d) comparative responses of E. nitens and E. globulus to live branch pruning. Results of a field experiment indicated that removal of between 30 and 50% of the crown length was appropriate for E. globulus plantations verging on canopy closure. The significant reduction in height growth associated with removal of 50 or 70% of crown length suggested pruning should remain below 50% of crown length if reduced stem growth of pruned trees was to be avoided. Stem volume was only significantly reduced over the period of the experiment by 70% pruning, but it was estimated that standing volume following removal of 50% of crown length would be reduced by 82m super(3)ha super(-) super(1) over a 20-year rotation if there were no other silvicultural interventions. The growth responses observed were probably related to large reductions in leaf area following 50 or 70% removal of crown length. Trees responded to pruning by changing patterns of biomass partitioning to favour stem growth at the expense of branch growth. A glasshouse study determined that light-saturated net CO sub(2) uptake (A sub(m) sub(a) sub(x)) increased following pruning. E. nitens seedlings had both a higher baseline A sub(m) sub(a) sub(x) and higher A sub(m) sub(a) sub(x) following pruning than did E. globulus, which could partially explain the greater effect of pruning on E. globulus growth than has been observed for E. nitens in other studies. This result, as well as apparently different patterns of foliage distribution through the crowns of E. globulus and E. nitens, suggested that models of pruning responses need to be parameterised for both species. In addition, a more conservative pruning regime may be appropriate for E. globulus than E. nitens. Pruning increased the frequency of branch traces with decay infection, and there was a trend towards increasing decay outbreaks with increasing pruning severity. Decay outbreaks were more likely to occur following pruning of high angle or larger diameter branches. JF - Forest Ecology and Management AU - Pinkard, E A AU - Mohammed, C AU - Beadle, CL AU - Hall, M F AU - Worledge, D AU - Mollon, A AD - Cooperative Research Centre for Sustainable Production Forestry, Private Bag 12, GPO Hobart 7000, Australia, libby.pinkard@ffp.csiro.au Y1 - 2004/10/25/ PY - 2004 DA - 2004 Oct 25 SP - 263 EP - 277 VL - 200 IS - 1-3 SN - 0378-1127, 0378-1127 KW - Ecology Abstracts KW - Forest management KW - Foliage KW - Branches KW - Trees KW - Canopies KW - Decay KW - Pruning KW - Carbon dioxide KW - Plantations KW - Eucalyptus globulus KW - Eucalyptus nitens KW - D 04700:Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17763908?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forest+Ecology+and+Management&rft.atitle=Growth+responses%2C+physiology+and+decay+associated+with+pruning+plantation-grown+Eucalyptus+globulus+Labill.+and+E.+nitens+%28Deane+and+Maiden%29+Maiden&rft.au=Pinkard%2C+E+A%3BMohammed%2C+C%3BBeadle%2C+CL%3BHall%2C+M+F%3BWorledge%2C+D%3BMollon%2C+A&rft.aulast=Pinkard&rft.aufirst=E&rft.date=2004-10-25&rft.volume=200&rft.issue=1-3&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=Forest+Ecology+and+Management&rft.issn=03781127&rft_id=info:doi/10.1016%2Fj.foreco.2004.07.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eucalyptus nitens; Eucalyptus globulus; Pruning; Decay; Branches; Plantations; Trees; Carbon dioxide; Canopies; Foliage; Forest management DO - http://dx.doi.org/10.1016/j.foreco.2004.07.004 ER - TY - JOUR T1 - Engineering high-level aluminum tolerance in barley with the ALMT1 gene. AN - 66990510; 15471989 AB - Acidity is a serious limitation to plant production on many of the world's agricultural soils. Toxic aluminium (Al) cations solubilized by the acidity rapidly inhibit root growth and limit subsequent uptake of water and nutrients. Recent work has shown that the ALMT1 gene of wheat (Triticum aestivum) encodes a malate transporter that is associated with malate efflux and Al tolerance. We generated transgenic barley (Hordeum vulgare) plants expressing ALMT1 and assessed their ability to exude malate and withstand Al stress. ALMT1 expression in barley conferred an Al-activated efflux of malate with properties similar to those of Al-tolerant wheat. The transgenic barley showed a high level of Al tolerance when grown in both hydroponic culture and on acid soils. These findings provide additional evidence that ALMT1 is a major Al-tolerance gene and demonstrate its ability to confer effective tolerance to acid soils through a transgenic approach in an important crop species. JF - Proceedings of the National Academy of Sciences of the United States of America AU - Delhaize, Emmanuel AU - Ryan, Peter R AU - Hebb, Diane M AU - Yamamoto, Yoko AU - Sasaki, Takayuki AU - Matsumoto, Hideaki AD - Commonwealth Scientific and Industrial Research Organization Plant Industry, GPO Box 1600, Canberra ACT 2601, Australia. manny.delhaize@csiro.au Y1 - 2004/10/19/ PY - 2004 DA - 2004 Oct 19 SP - 15249 EP - 15254 VL - 101 IS - 42 SN - 0027-8424, 0027-8424 KW - DNA, Plant KW - 0 KW - Malates KW - Plant Proteins KW - Recombinant Proteins KW - malic acid KW - 817L1N4CKP KW - Aluminum KW - CPD4NFA903 KW - Index Medicus KW - Biological Transport, Active -- drug effects KW - Base Sequence KW - DNA, Plant -- genetics KW - Recombinant Proteins -- metabolism KW - Plants, Genetically Modified KW - Genetic Engineering KW - Plant Proteins -- genetics KW - Recombinant Proteins -- genetics KW - Plant Proteins -- metabolism KW - Malates -- metabolism KW - Hordeum -- drug effects KW - Hordeum -- genetics KW - Genes, Plant KW - Aluminum -- toxicity KW - Hordeum -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66990510?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Engineering+high-level+aluminum+tolerance+in+barley+with+the+ALMT1+gene.&rft.au=Delhaize%2C+Emmanuel%3BRyan%2C+Peter+R%3BHebb%2C+Diane+M%3BYamamoto%2C+Yoko%3BSasaki%2C+Takayuki%3BMatsumoto%2C+Hideaki&rft.aulast=Delhaize&rft.aufirst=Emmanuel&rft.date=2004-10-19&rft.volume=101&rft.issue=42&rft.spage=15249&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.issn=00278424&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-22 N1 - Date created - 2004-10-20 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Planta. 2003 Sep;217(5):794-800 [12734756] Plant J. 2004 Mar;37(5):645-53 [14871306] Curr Biol. 1996 Mar 1;6(3):325-30 [8805250] Science. 1997 Jun 6;276(5318):1566-8 [9171061] Plant Physiol. 2000 Mar;122(3):657-65 [10712528] Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11655-60 [11027363] Plant Physiol. 2003 Aug;132(4):2256-66 [12913180] Plant Physiol. 2001 Mar;125(3):1459-72 [11244125] Plant Physiol. 2001 Apr;125(4):2059-67 [11299385] Trends Plant Sci. 2001 Jun;6(6):273-8 [11378470] Plant Physiol. 2001 Dec;127(4):1836-44 [11743127] Plant Cell. 2003 May;15(5):1131-42 [12724539] Plant Physiol. 2003 Aug;132(4):2205-17 [12913175] Plant Cell Physiol. 2000 Sep;41(9):1030-7 [11100775] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Strain differences of cadmium-induced hepatotoxicity in Wistar-Imamichi and Fischer 344 rats: involvement of cadmium accumulation. AN - 66876101; 15363594 AB - We previously reported that Wistar-Imamichi (WI) rats have a strong resistance to cadmium (Cd)-induced lethality compared to other strains such as Fischer 344 (Fischer) rats. The present study was designed to establish biochemical and histological differences in Cd toxicity in WI and Fischer rats, and to clarify the mechanistic basis of these strain differences. A single Cd (4.5 mg/kg, s.c.) treatment caused a significant increase in serum alanine aminotransferase activity, indicative of hepatotoxicity, in Fischer rats, but did not in WI rats. This difference in hepatotoxic response to Cd was supported by pathological analysis. After treatment with Cd at doses of 3.0, 3.5 and 4.5 mg/kg, the hepatic and renal accumulation of Cd was significantly lower in the WI rats than in the Fischer rats, indicating a kinetic mechanism for the observed strain differences in Cd toxicity. Thus, the remarkable resistance to Cd-induced hepatotoxicity in WI rats is associated, at least in part, with a lower tissue accumulation of the metal. Hepatic and renal zinc (Zn) contents after administration were similarly lower in WI than in Fischer rats. When Zn was administered in combination with Cd to Fischer rats, it decreased Cd contents in the liver and kidney, and exhibited a significant protective effect against the toxicity of Cd. We propose the possibility that Zn transporter plays an important role in the strain difference of Cd toxicity in WI and Fischer rats. JF - Toxicology AU - Shimada, Hideaki AU - Takamure, Yasutaka AU - Shimada, Akinori AU - Yasutake, Akira AU - Waalkes, Michael P AU - Imamura, Yorishige AD - Faculty of Education, Kumamoto University, 2-40-1, Kurokami, 860-8555, Japan. hshimada@gpo.kumamoto-u.ac.jp Y1 - 2004/10/15/ PY - 2004 DA - 2004 Oct 15 SP - 189 EP - 197 VL - 203 IS - 1-3 SN - 0300-483X, 0300-483X KW - Cadmium KW - 00BH33GNGH KW - Metallothionein KW - 9038-94-2 KW - Iron KW - E1UOL152H7 KW - Alanine Transaminase KW - EC 2.6.1.2 KW - Zinc KW - J41CSQ7QDS KW - Index Medicus KW - Animals KW - Kidney -- metabolism KW - Liver -- pathology KW - Kidney -- pathology KW - Iron -- pharmacology KW - Alanine Transaminase -- metabolism KW - Zinc -- metabolism KW - Liver -- metabolism KW - Blood Urea Nitrogen KW - Iron -- metabolism KW - Rats KW - Zinc -- pharmacology KW - Rats, Inbred F344 KW - Rats, Wistar KW - Species Specificity KW - Male KW - Metallothionein -- metabolism KW - Cadmium Poisoning -- metabolism KW - Cadmium -- metabolism KW - Chemical and Drug Induced Liver Injury -- pathology KW - Cadmium Poisoning -- complications KW - Chemical and Drug Induced Liver Injury -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66876101?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Strain+differences+of+cadmium-induced+hepatotoxicity+in+Wistar-Imamichi+and+Fischer+344+rats%3A+involvement+of+cadmium+accumulation.&rft.au=Shimada%2C+Hideaki%3BTakamure%2C+Yasutaka%3BShimada%2C+Akinori%3BYasutake%2C+Akira%3BWaalkes%2C+Michael+P%3BImamura%2C+Yorishige&rft.aulast=Shimada&rft.aufirst=Hideaki&rft.date=2004-10-15&rft.volume=203&rft.issue=1-3&rft.spage=189&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-19 N1 - Date created - 2004-09-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Perspective: Emergency medicine and environmental activism AN - 745604925; 6218550 AB - Clearfell, burn and sow silviculture is promoted as being the most scientific method of harvesting wet sclerophyll forests in Tasmania. However, it fails to take into account wider social and global environmental issues such as climate change and the carbon cycle. This paper describes an emergency physician's role in the continuing debate surrounding the management of Tasmania's old-growth forests. Like evidence-based medicine, the use of science in this context has its limitations, and such comparisons are discussed. JF - Emergency Medicine Australasia AU - Couser, Geoff AD - Dr Geoff Couser, Department of Emergency Medicine, Royal Hobart Hospital, GPO Box 1061, Hobart, Tas. 7001, Australia, gcouser@utas.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 469 EP - 472 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 16 IS - 5-6 SN - 1742-6731, 1742-6731 KW - Sustainability Science Abstracts KW - Burns KW - silviculture KW - harvesting KW - Climatic changes KW - Carbon cycle KW - Forests KW - environmentalism KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745604925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Emergency+Medicine+Australasia&rft.atitle=Perspective%3A+Emergency+medicine+and+environmental+activism&rft.au=Couser%2C+Geoff&rft.aulast=Couser&rft.aufirst=Geoff&rft.date=2004-10-01&rft.volume=16&rft.issue=5-6&rft.spage=469&rft.isbn=&rft.btitle=&rft.title=Emergency+Medicine+Australasia&rft.issn=17426731&rft_id=info:doi/10.1111%2Fj.1742-6723.2004.00652.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - SuppNotes - References, 13. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Burns; silviculture; harvesting; Climatic changes; Carbon cycle; Forests; environmentalism DO - http://dx.doi.org/10.1111/j.1742-6723.2004.00652.x ER - TY - JOUR T1 - Repellency of essential oils of some Kenyan plants against Anopheles gambiae. AN - 66960927; 15474566 AB - Essential oils of six plants growing in Kenya were screened for repellent activities against Anopheles gambiae sensu stricto. The oils of Conyza newii (Compositeae) and Plectranthus marrubioides (Labiateae) were the most repellent (RD50=8.9 x 10(-5) mg cm(-2), 95% CI) followed by Lippia javanica (Verbenaceae), Lippia ukambensis (Verbenaceae), Tetradenia riparia, (Iboza multiflora) (Labiateae) and Tarchonanthus camphoratus (Compositeae). Eight constituents of the different oils (perillyl alcohol, cis-verbenol, cis-carveol, geraniol, citronellal, perillaldehyde, caryophyllene oxide and a sesquiterpene alcohol) exhibited relatively high repellency. Four synthetic blends of the major components (present in > or = 1.5%) of the essential oils were found to exhibit comparable repellent activity to the parent oils. JF - Phytochemistry AU - Omolo, Maurice O AU - Okinyo, Denis AU - Ndiege, Isaiah O AU - Lwande, Wilber AU - Hassanali, Ahmed AD - Chemistry Department, School of Pure and Applied Sciences, Kenyatta University, PO Box 43844, GPO 00100, Nairobi, Kenya. Y1 - 2004/10// PY - 2004 DA - October 2004 SP - 2797 EP - 2802 VL - 65 IS - 20 SN - 0031-9422, 0031-9422 KW - Insect Repellents KW - 0 KW - Oils, Volatile KW - Index Medicus KW - Animals KW - Kenya KW - Plants -- chemistry KW - Oils, Volatile -- pharmacology KW - Oils, Volatile -- chemistry KW - Anopheles gambiae -- drug effects KW - Insect Repellents -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66960927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Phytochemistry&rft.atitle=Repellency+of+essential+oils+of+some+Kenyan+plants+against+Anopheles+gambiae.&rft.au=Omolo%2C+Maurice+O%3BOkinyo%2C+Denis%3BNdiege%2C+Isaiah+O%3BLwande%2C+Wilber%3BHassanali%2C+Ahmed&rft.aulast=Omolo&rft.aufirst=Maurice&rft.date=2004-10-01&rft.volume=65&rft.issue=20&rft.spage=2797&rft.isbn=&rft.btitle=&rft.title=Phytochemistry&rft.issn=00319422&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-01-31 N1 - Date created - 2004-10-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Governing street-based injecting drug users: a critique of heroin overdose prevention in Australia. AN - 66701993; 15246182 AB - This article provides a critical analysis of existing approaches to the prevention of heroin overdose in Australia. It draws on almost 2 years of ethnographic research with street-based injecting drug users (IDUs), street-based sex workers and service providers in Melbourne, Australia's second largest city, and on recent anthropological and sociological work on governmentality. The substantive sections of the article argue: (1) that heroin overdose prevention in Australia contains implicit or explicit assumptions of rationality and personal autonomy, continues to emphasise individual behaviour change and inscribes a self-disciplined, self-aware, self-regulating subject; and (2) that the social, cultural and economic realities--the 'lived experience'--of street-based IDUs and sex workers may undermine or hinder the successful adoption of overdose prevention strategies. The paper concludes by arguing that the 'chaotic' practices of street-based IDUs and sex workers arise in response to particular 'risk environments', and that individually focused overdose prevention strategies, while an important first step, need to be complemented by measures addressing the macro- and micro-aspects of risk environments. JF - Social science & medicine (1982) AU - Moore, David AD - National Drug Research Institute, Curtin University of Technology, GPO Box U1987, Perth WA 6845, Australia. d.moore@curtin.edu.au Y1 - 2004/10// PY - 2004 DA - October 2004 SP - 1547 EP - 1557 VL - 59 IS - 7 SN - 0277-9536, 0277-9536 KW - Index Medicus KW - Victoria KW - Risk-Taking KW - Humans KW - Adult KW - Australia KW - Social Conditions KW - Female KW - Anthropology, Cultural KW - Social Control, Formal KW - Sex Work -- psychology KW - Drug Overdose -- prevention & control KW - Heroin Dependence -- psychology KW - Substance Abuse, Intravenous -- psychology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66701993?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+science+%26+medicine+%281982%29&rft.atitle=Governing+street-based+injecting+drug+users%3A+a+critique+of+heroin+overdose+prevention+in+Australia.&rft.au=Moore%2C+David&rft.aulast=Moore&rft.aufirst=David&rft.date=2004-10-01&rft.volume=59&rft.issue=7&rft.spage=1547&rft.isbn=&rft.btitle=&rft.title=Social+science+%26+medicine+%281982%29&rft.issn=02779536&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-19 N1 - Date created - 2004-07-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The 9/11 Commission Report: Final Report of the National Commission on Terrorist Attacks upon the United States AN - 59705764; 200607713 JF - Medunarodne studije AU - Nakic, Mladen AU - Nakic, Mladen Y1 - 2004/10// PY - 2004 DA - October 2004 SP - 201 EP - 204 VL - 4 IS - 3-4 SN - 1332-4756, 1332-4756 KW - article KW - 9105: politics; national-level politics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59705764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Medunarodne+studije&rft.atitle=The+9%2F11+Commission+Report%3A+Final+Report+of+the+National+Commission+on+Terrorist+Attacks+upon+the+United+States&rft.au=Nakic%2C+Mladen%3BU.S.+Congress&rft.aulast=Nakic&rft.aufirst=Mladen&rft.date=2004-10-01&rft.volume=4&rft.issue=3-4&rft.spage=201&rft.isbn=&rft.btitle=&rft.title=Medunarodne+studije&rft.issn=13324756&rft_id=info:doi/ LA - Serbo-Croatian with Roman alphabet/Croatian DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - SuppNotes - Edition date: 2004. Language of document reviewed: English. N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Developing a Comprehensive Pesticide Health Effects Tracking System for an Urban Setting: New York City's Approach AN - 21430237; 12429537 AB - In recent years, there have been substantial investments and improvements in federal and state surveillance systems to track the health effects from pesticide exposure. These surveillance systems help to identify risk factors for occupational exposure to pesticides, patterns in poisonings, clusters of disease, and populations at risk of exposure from pesticide use. Data from pesticide use registries and recent epidemiologic evidence pointing to health risks from urban residential pesticide use make a strong case for understanding better the sale, application, and use of pesticides in cities. In this article, we describe plans for the development of a pesticide tracking system for New York City that will help to elucidate where and why pesticides are used, potential risks to varied populations, and the health consequences of their use. The results of an inventory of data sources are presented along with a description of their relevance to pesticide tracking. We also discuss practical, logistical, and methodologic difficulties of linking multiple secondary data sources with different levels of person, place, and time descriptors. JF - Environmental Health Perspectives AU - Kass, Daniel E AU - Thier, Audrey L AU - Leighton, Jessica AU - Cone, James E AU - Jeffery, Nancy L Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1419 EP - 1423 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Risk assessment KW - USA, New York, New York City KW - Pesticides KW - Poisoning KW - Occupational exposure KW - Urban areas KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21430237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developing+a+Comprehensive+Pesticide+Health+Effects+Tracking+System+for+an+Urban+Setting%3A+New+York+City%27s+Approach&rft.au=Kass%2C+Daniel+E%3BThier%2C+Audrey+L%3BLeighton%2C+Jessica%3BCone%2C+James+E%3BJeffery%2C+Nancy+L&rft.aulast=Kass&rft.aufirst=Daniel&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1419&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Risk assessment; Pesticides; Poisoning; Occupational exposure; Urban areas; USA, New York, New York City ER - TY - JOUR T1 - Does Particulate Air Pollution Contribute to Infant Death? A Systematic Review AN - 21423601; 12429543 AB - There is now substantial evidence that both short- and long-term increases in ambient air pollution are associated with increased mortality and morbidity in adults and children. Children's health is particularly vulnerable to environmental pollution, and infant mortality is still a major contributor to childhood mortality. In this systematic review we summarize and evaluate the current level of epidemiologic evidence of an association between particulate air pollution and infant mortality. We identified relevant publications using database searches with a comprehensive list of search terms and other established search methods. We included articles in the review according to specified inclusion criteria. Fifteen studies met our inclusion criteria. Evidence of an association between particulate air pollution and infant mortality in general was inconsistent, being reported from locations with largely comparable pollution levels. There was some evidence that the strength of association with particulate matter differed by subgroups of infant mortality. It was more consistent for postneonatal mortality due to respiratory causes and sudden infant death syndrome. Differential findings for various mortality subgroups within studies suggest a stronger association of particulate air pollution with some causes of infant death. Research is needed to confirm and clarify these links, using the most appropriate methodologies for exposure assessment and control of confounders. JF - Environmental Health Perspectives AU - Glinianaia, Svetlana V AU - Rankin, Judith AU - Bell, Ruth AU - Pless-Mulloli, Tanja AU - Howel, Denise Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1365 EP - 1371 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts; Environment Abstracts KW - Mortality KW - pollution levels KW - infant mortality KW - Pollution effects KW - Particulates KW - Children KW - Morbidity KW - Air pollution KW - Reviews KW - vulnerability KW - Infants KW - sudden infant death syndrome KW - P 0000:AIR POLLUTION KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423601?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Does+Particulate+Air+Pollution+Contribute+to+Infant+Death%3F+A+Systematic+Review&rft.au=Glinianaia%2C+Svetlana+V%3BRankin%2C+Judith%3BBell%2C+Ruth%3BPless-Mulloli%2C+Tanja%3BHowel%2C+Denise&rft.aulast=Glinianaia&rft.aufirst=Svetlana&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1365&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Air pollution; Mortality; pollution levels; infant mortality; Reviews; Pollution effects; vulnerability; Particulates; Children; Morbidity; sudden infant death syndrome; Infants ER - TY - JOUR T1 - Quinones and Aromatic Chemical Compounds in Particulate Matter Induce Mitochondrial Dysfunction: Implications for Ultrafine Particle Toxicity AN - 21423335; 12429542 AB - Particulate pollutants cause adverse health effects through the generation of oxidative stress. A key question is whether these effects are mediated by the particles or their chemical compounds. In this article we show that aliphatic, aromatic, and polar organic compounds, fractionated from diesel exhaust particles (DEPs), exert differential toxic effects in RAW 264.7 cells. Cellular analyses showed that the quinone-enriched polar fraction was more potent than the polycyclic aromatic hydrocarbon (PAH)-enriched aromatic fraction in O2 .- generation, decrease of membrane potential (Delta-Psi m), loss of mitochondrial membrane mass, and induction of apoptosis. A major effect of the polar fraction was to promote cyclosporin A (CsA)-sensitive permeability transition pore (PTP) opening in isolated liver mitochondria. This opening effect is dependent on a direct effect on the PTP at low doses as well as on an effect on Delta-Psi m at high doses in calcium (Ca2+)-loaded mitochondria. The direct PTP effect was mimicked by redox-cycling DEP quinones. Although the aliphatic fraction failed to perturb mitochondrial function, the aromatic fraction increased the Ca2+ retention capacity at low doses and induced mitochondrial swelling and a decrease in Delta-Psi m at high doses. This swelling effect was mostly CsA insensitive and could be reproduced by a mixture of PAHs present in DEPs. These chemical effects on isolated mitochondria could be reproduced by intact DEPs as well as ambient ultrafine particles (UFPs). In contrast, commercial polystyrene nanoparticles failed to exert mitochondrial effects. These results suggest that DEP and UFP effects on the PTP and Delta-Psi m are mediated by adsorbed chemicals rather than the particles themselves. JF - Environmental Health Perspectives AU - Xia, Tian AU - Korge, Paavo AU - Weiss, James N AU - Li, Ning Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1347 EP - 1358 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Permeability KW - Membranes KW - Calcium KW - Liver KW - polycyclic aromatic hydrocarbons KW - Particulates KW - Toxicity KW - Diesel engines KW - oxidative stress KW - ENA 09:Land Use & Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423335?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Quinones+and+Aromatic+Chemical+Compounds+in+Particulate+Matter+Induce+Mitochondrial+Dysfunction%3A+Implications+for+Ultrafine+Particle+Toxicity&rft.au=Xia%2C+Tian%3BKorge%2C+Paavo%3BWeiss%2C+James+N%3BLi%2C+Ning&rft.aulast=Xia&rft.aufirst=Tian&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1347&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Permeability; Calcium; Membranes; Liver; polycyclic aromatic hydrocarbons; Toxicity; Particulates; Diesel engines; oxidative stress ER - TY - JOUR T1 - Using the Behavioral Risk Factor Surveillance System (BRFSS) for Exposure Tracking: Experiences from Washington State AN - 21422586; 12429536 AB - One of the goals of the National Environmental Public Health Tracking Network is to link environmental data with chronic disease data as a means of improving our understanding of the environmental determinants of disease. Such efforts will rely on the ongoing collection of population exposure information, and there are few systems in place to track population exposures. In many cases, exposures can be estimated by combining environmental contaminant data with data about human behaviors. The Behavioral Risk Factor Surveillance System (BRFSS) provides a good opportunity to implement tracking of exposure-related behaviors. Washington State has used the BRFSS to collection information on environmentally related knowledge, attitudes, and behaviors. In this article we present case studies of modules covering drinking water, perceptions of environmental risk, and radon awareness and testing. Data on exposure-related behaviors have been useful for population exposure assessments and program evaluation. Questions about knowledge and attitudes and perceptions of environmental issues were not as useful because they lacked sufficient detail from which to modify existing education efforts. In some cases these data had not been used at all, indicating that the need for the data had not been well established. National development efforts should focus on compiling existing questions and developing questions on topics that are a priority at the state and national levels to be included as core questions and optional modules in future BRFSS surveys. JF - Environmental Health Perspectives AU - Laflamme, Denise M AU - VanDerslice, James A Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1428 EP - 1433 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - case studies KW - USA, Washington KW - Data collection KW - Education KW - Perception KW - Human factors KW - Drinking water KW - attitudes KW - Radon KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21422586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+the+Behavioral+Risk+Factor+Surveillance+System+%28BRFSS%29+for+Exposure+Tracking%3A+Experiences+from+Washington+State&rft.au=Laflamme%2C+Denise+M%3BVanDerslice%2C+James+A&rft.aulast=Laflamme&rft.aufirst=Denise&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1428&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - case studies; Education; Data collection; Perception; Human factors; Drinking water; Radon; attitudes; USA, Washington ER - TY - JOUR T1 - Identifying Priority Health Conditions, Environmental Data, and Infrastructure Needs: A Synopsis of the Pew Environmental Health Tracking Project AN - 21417289; 12429547 AB - In this article we describe the methodologic approaches of the Pew Environmental Health Commission at the Johns Hopkins Bloomberg School of Public Health used to identify priority environmental health conditions and develop recommendations to establish a national environmental public health tracking network. We present the results of a survey of public health and environmental practitioners to uncover state and local health tracking needs and priorities. We describe the steps that combined the findings from the state and local health tracking survey and a review of the state of the science on environmental impacts on health to identify priority health end points. Through an examination of national health and health care databases, we then describe trends and public health effects of those diseases that may be linked to the environment. Based on this analysis, respiratory diseases and neurologic diseases are recommended as priorities for tracking. Specific end points recommended for tracking include asthma and chronic respiratory diseases, and chronic neurodegenerative diseases such as multiple sclerosis. Based on trends in reported prevalence, consideration should also be given to developmental disabilities, reproductive disorders, and endocrine/metabolic disorders. Strengthening of current efforts to track cancer and birth defects should also be included as components of a nationwide health tracking network. Finally, we present the recommendations for environmental public health tracking. These recommendations provided the groundwork for the development of the Centers for Disease Control and Prevention's National Environmental Public Health Tracking Progam that now includes 21 states, three cities, and three academic centers throughout the nation. JF - Environmental Health Perspectives AU - Litt, Jill AU - Tran, Nga AU - Malecki, Kristen Chossek AU - Neff, Roni Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1414 EP - 1418 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Data collection KW - prevention KW - Environmental health KW - Asthma KW - Respiratory diseases KW - disease control KW - Cancer KW - Public health KW - Urban areas KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21417289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Identifying+Priority+Health+Conditions%2C+Environmental+Data%2C+and+Infrastructure+Needs%3A+A+Synopsis+of+the+Pew+Environmental+Health+Tracking+Project&rft.au=Litt%2C+Jill%3BTran%2C+Nga%3BMalecki%2C+Kristen+Chossek%3BNeff%2C+Roni&rft.aulast=Litt&rft.aufirst=Jill&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1414&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Data collection; prevention; Asthma; Environmental health; Respiratory diseases; disease control; Cancer; Urban areas; Public health ER - TY - JOUR T1 - Estimated Risk for Altered Fetal Growth Resulting from Exposure to Fine Particles during Pregnancy: An Epidemiologic Prospective Cohort Study in Poland AN - 21417240; 12429539 AB - The purpose of this study was to estimate exposure of pregnant women in Poland to fine particulate matter [less than or equal to 2.5 microm in diameter (PM 2.5)] and to assess its effect on the birth outcomes. The cohort consisted of 362 pregnant women who gave birth between 34 and 43 weeks of gestation. The enrollment included only nonsmoking women with singleton pregnancies, 18-35 years of age, who were free from chronic diseases such as diabetes and hypertension. PM 2.5 was measured by personal air monitoring over 48 hr during the second trimester of pregnancy. All assessed birth effects were adjusted in multiple linear regression models for potential confounding factors such as the size of mother (maternal height, prepregnancy weight), parity, sex of child, gestational age, season of birth, and self-reported environmental tobacco smoke (ETS). The regression model explained 35% of the variability in birth weight (beta = -200.8, p = 0.03), and both regression coefficients for PM 2.5 and birth length (beta = -1.44, p = 0.01) and head circumference (HC; beta = -0.73, p = 0.02) were significant as well. In all regression models, the effect of ETS was insignificant. Predicted reduction in birth weight at an increase of exposure from 10 to 50 microg/m3 was 140.3 g. The corresponding predicted reduction of birth length would be 1.0 cm, and of HC, 0.5 cm. The study provides new and convincing epidemiologic evidence that high personal exposure to fine particles is associated with adverse effects on the developing fetus. These results indicate the need to reduce ambient fine particulate concentrations. However, further research should establish possible biologic mechanisms explaining the observed relationship. JF - Environmental Health Perspectives AU - Jedrychowski, Wieslaw AU - Bendkowska, Ivona AU - Flak, Elzbieta AU - Penar, Agnieszka Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1398 EP - 1402 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Pollution monitoring KW - Age KW - parity KW - Passive smoking KW - Poland KW - hypertension KW - birth weight KW - Particulates KW - Side effects KW - Pregnancy KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21417240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Estimated+Risk+for+Altered+Fetal+Growth+Resulting+from+Exposure+to+Fine+Particles+during+Pregnancy%3A+An+Epidemiologic+Prospective+Cohort+Study+in+Poland&rft.au=Jedrychowski%2C+Wieslaw%3BBendkowska%2C+Ivona%3BFlak%2C+Elzbieta%3BPenar%2C+Agnieszka&rft.aulast=Jedrychowski&rft.aufirst=Wieslaw&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1398&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Pollution monitoring; parity; Age; Passive smoking; hypertension; birth weight; Particulates; Side effects; Pregnancy; Poland ER - TY - JOUR T1 - Statistical Methods for Linking Health, Exposure, and Hazards AN - 21406612; 12429535 AB - The Environmental Public Health Tracking Network (EPHTN) proposes to link environmental hazards and exposures to health outcomes. Statistical methods used in case-control and cohort studies to link health outcomes to individual exposure estimates are well developed. However, reliable exposure estimates for many contaminants are not available at the individual level. In these cases, exposure/hazard data are often aggregated over a geographic area, and ecologic models are used to relate health outcome and exposure/hazard. Ecologic models are not without limitations in interpretation. EPHTN data are characteristic of much information currently being collected--they are multivariate, with many predictors and response variables, often aggregated over geographic regions (small and large) and correlated in space and/or time. The methods to model trends in space and time, handle correlation structures in the data, estimate effects, test hypotheses, and predict future outcomes are relatively new and without extensive application in environmental public health. In this article we outline a tiered approach to data analysis for EPHTN and review the use of standard methods for relating exposure/hazards, disease mapping and clustering techniques, Bayesian approaches, Markov chain Monte Carlo methods for estimation of posterior parameters, and geostatistical methods. The advantages and limitations of these methods are discussed. JF - Environmental Health Perspectives AU - Mather, Frances Jean AU - White, LuAnn Ellis AU - Langlois, Elizabeth Cullen AU - Shorter, Charles Franklin Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1440 EP - 1445 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Monte Carlo simulation KW - Hazards KW - Data collection KW - Reviews KW - Mapping KW - environmental hazards KW - Public health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406612?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Statistical+Methods+for+Linking+Health%2C+Exposure%2C+and+Hazards&rft.au=Mather%2C+Frances+Jean%3BWhite%2C+LuAnn+Ellis%3BLanglois%2C+Elizabeth+Cullen%3BShorter%2C+Charles+Franklin&rft.aulast=Mather&rft.aufirst=Frances&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1440&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Hazards; Monte Carlo simulation; Data collection; Reviews; Mapping; environmental hazards; Public health ER - TY - JOUR T1 - Acute Infections and Environmental Exposure to Organochlorines in Inuit Infants from Nunavik AN - 21406140; 12429553 AB - The Inuit population of Nunavik (Canada) is exposed to immunotoxic organochlorines (OCs) mainly through the consumption of fish and marine mammal fat. We investigated the effect of perinatal exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) on the incidence of acute infections in Inuit infants. We reviewed the medical charts of a cohort of 199 Inuit infants during the first 12 months of life and evaluated the incidence rates of upper and lower respiratory tract infections (URTI and LRTIs, respectively), otitis media, and gastrointestinal (GI) infections. Maternal plasma during delivery and infant plasma at 7 months of age were sampled and assayed for PCBs and DDE. Compared to rates for infants in the first quartile of exposure to PCBs (least exposed), adjusted rate ratios for infants in higher quartiles ranged between 1.09 and 1.32 for URTIs, 0.99 and 1.39 for otitis, 1.52 and 1.89 for GI infections, and 1.16 and 1.68 for LRTIs during the first 6 months of follow-up. For all infections combined, the rate ratios ranged from 1.17 to 1.27. The effect size was similar for DDE exposure but was lower for the full 12-month follow-up. Globally, most rate ratios were 1.0, but few were statistically significant (p 0.05). No association was found when postnatal exposure was considered. These results show a possible association between prenatal exposure to OCs and acute infections early in life in this Inuit population. JF - Environmental Health Perspectives AU - Dallaire, Frederic AU - Dewailly, Eric AU - Muckle, Gina AU - Vezina, Carole Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1359 EP - 1365 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - Organochlorine compounds KW - Chlorine compounds KW - Respiration KW - DDE KW - Outer continental shelf KW - Toxicity tests KW - Environmental factors KW - Insecticides KW - Nitrous oxide KW - Canada, Quebec, Nunavik KW - infection KW - Fish KW - PCB compounds KW - Pollution indicators KW - PCB KW - Metabolism KW - Infants KW - Respiratory tract KW - Q5 08504:Effects on organisms KW - ENA 12:Oceans & Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Acute+Infections+and+Environmental+Exposure+to+Organochlorines+in+Inuit+Infants+from+Nunavik&rft.au=Dallaire%2C+Frederic%3BDewailly%2C+Eric%3BMuckle%2C+Gina%3BVezina%2C+Carole&rft.aulast=Dallaire&rft.aufirst=Frederic&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1359&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Chlorine compounds; Respiration; DDE; Outer continental shelf; Environmental factors; Pollution indicators; Toxicity tests; Metabolism; PCB; Organochlorine compounds; Insecticides; Nitrous oxide; infection; Fish; PCB compounds; Respiratory tract; Infants; Canada, Quebec, Nunavik ER - TY - JOUR T1 - Tracking Pediatric Asthma: The Massachusetts Experience Using School Health Records AN - 21406071; 12429546 AB - The Massachusetts Department of Public Health, in collaboration with the U.S. Centers for Disease Control and Prevention Environmental Public Health Tracking Program, initiated a 3-year statewide project for the routine surveillance of asthma in children using school health records as the primary data source. School district nurse leaders received electronic data reporting forms requesting the number of children with asthma by grade and gender for schools serving grades kindergarten (K) through 8. Verification efforts from an earlier community-level study comparing a select number of school health records with primary care provider records demonstrated a high level of agreement (i.e., 95%). First-year surveillance targeted approximately one-half (n = 958 schools) of all Massachusetts's K-8 schools. About 78% of targeted school districts participated, and 70% of the targeted schools submitted complete asthma data. School nurse-reported asthma prevalence was as high as 30.8% for schools, with a mean of 9.2%. School-based asthma surveillance has been demonstrated to be a reliable and cost-effective method of tracking disease through use of an existing and enhanced reporting structure. JF - Environmental Health Perspectives AU - Knorr, Robert S AU - Condon, Suzanne K AU - Dwyer, Frances M AU - Hoffman, Danielle F Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1424 EP - 1427 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Data collection KW - USA, Massachusetts KW - schools KW - Economics KW - prevention KW - Asthma KW - Respiratory diseases KW - Children KW - Medical personnel KW - Public health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406071?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Tracking+Pediatric+Asthma%3A+The+Massachusetts+Experience+Using+School+Health+Records&rft.au=Knorr%2C+Robert+S%3BCondon%2C+Suzanne+K%3BDwyer%2C+Frances+M%3BHoffman%2C+Danielle+F&rft.aulast=Knorr&rft.aufirst=Robert&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1424&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Data collection; schools; Economics; prevention; Asthma; Respiratory diseases; Children; Medical personnel; Public health; USA, Massachusetts ER - TY - JOUR T1 - Setting a New Syllabus: Environmental Health Science in the Classroom AN - 21399423; 12429554 AB - Environmental health is a subject that has only relatively recently become prominent in the social consciousness. Even as its significance becomes known, finding ways to integrate the subject into education for primary and secondary students is difficult because of federal testing requirements under the No Child Left Behind Act of 2001 and other demands placed on teachers. A number of efforts are under way, however, to provide teachers with resources to help them bring environment health into their classrooms. JF - Environmental Health Perspectives AU - Brown, Valerie J Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - A814 EP - A819 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Education KW - Environmental health KW - ENA 04:Environmental Education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21399423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Setting+a+New+Syllabus%3A+Environmental+Health+Science+in+the+Classroom&rft.au=Brown%2C+Valerie+J&rft.aulast=Brown&rft.aufirst=Valerie&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=A814&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Education; Environmental health ER - TY - JOUR T1 - Effect of Breast Milk Lead on Infant Blood Lead Levels at 1 Month of Age AN - 21399397; 12429549 AB - Nursing infants may be exposed to lead from breast milk, but relatively few data exist with which to evaluate and quantify this relationship. This route of exposure constitutes a potential infant hazard from mothers with current ongoing exposure to lead as well as from mothers who have been exposed previously due to the redistribution of cumulative maternal bone lead stores. We studied the relationship between maternal breast milk lead and infant blood lead levels among 255 mother-infant pairs exclusively or partially breast-feeding through 1 month of age in Mexico City. A rigorous, well-validated technique was used to collect, prepare, and analyze the samples of breast milk to minimize the potential for environmental contamination and maximize the percent recovery of lead. Umbilical cord and maternal blood lead were measured at delivery; 1 month after delivery (+/- 5 days) maternal blood, bone, and breast milk and infant blood lead levels were obtained. Levels of lead at 1 month postpartum were, for breast milk, 0.3-8.0 microg/L (mean +/- SD, 1.5 +/- 1.2); maternal blood lead, 2.9-29.9 microg/dL (mean +/- SD, 9.4 +/- 4.5); and infant blood lead, 1.0-23.1 microg/dL (mean +/- SD, 5.5 +/- 3.0). Infant blood lead at 1 month postpartum was significantly correlated with umbilical cord (Spearman correlation coefficient rS = 0.40, p 0.0001) and maternal (rS= 0.42, p 0.0001) blood lead at delivery and with maternal blood (rS= 0.67, p 0.0001), patella rS = 0.19, p = 0.004), and breast milk (rS = 0.32, p 0.0001) lead at 1 month postpartum. Adjusting for cord blood lead, infant weight change, and reported breast-feeding status, a difference of approximately 2 microg/L (ppb; from the midpoint of the lowest quartile to the midpoint of the highest quartile) breast milk lead was associated with a 0.82 microg/dL increase in blood lead for breast-feeding infants at 1 month of age. Breast milk lead accounted for 12% of the variance of infant blood lead levels, whereas maternal blood lead accounted for 30%. Although these levels of lead in breast milk were low, they clearly have a strong influence on infant blood lead levels over and above the influence of maternal blood lead. Additional information on the lead content of dietary alternatives and interactions with other nutritional factors should be considered. However, because human milk is the best and most complete nutritional source for young infants, breast-feeding should be encouraged because the absolute values of the effects are small within this range of lead concentrations. JF - Environmental Health Perspectives AU - Ettinger, Adrienne S AU - Tellez-Rojo, Martha Maria AU - Amarasiriwardena, Chitra AU - Bellinger, David Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1381 EP - 1385 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Bone KW - Diets KW - Age KW - Mexico, Distrito Federal, Mexico City KW - Nutrition KW - Lead KW - Blood levels KW - Infants KW - breast milk KW - Urban areas KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21399397?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+of+Breast+Milk+Lead+on+Infant+Blood+Lead+Levels+at+1+Month+of+Age&rft.au=Ettinger%2C+Adrienne+S%3BTellez-Rojo%2C+Martha+Maria%3BAmarasiriwardena%2C+Chitra%3BBellinger%2C+David&rft.aulast=Ettinger&rft.aufirst=Adrienne&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1381&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Diets; Bone; Age; Nutrition; Lead; Urban areas; breast milk; Infants; Blood levels; Mexico, Distrito Federal, Mexico City ER - TY - JOUR T1 - The Fat of the Land: Do Agricultural Subsides Foster Poor Health? AN - 21399365; 12429544 AB - Since the 1920s, American farmers have received various forms of federal support in an effort to keep farmers farming and provide Americans with an affordable, stable food supply. Wheat, soybeans, and especially corn are currently the most highly subsidized crops; products made from these crops, including high-fructose corn syrup and hydrogenated fats, have flooded the market as cheap means for making foods tastier, though not healthier. Now critics are asking whether subsidies for these crops are actually driving the U.S. epidemic of obesity. JF - Environmental Health Perspectives AU - Fields, Scott Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - A820 EP - A823 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - wheat KW - Triticum aestivum KW - USA KW - Food supply KW - Economics KW - obesity KW - subsidies KW - Crops KW - corn KW - soybeans KW - ENA 06:Food & Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21399365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+occupational+hygiene&rft.atitle=Biological+monitoring+of+low+level+occupational+xylene+exposure+and+the+role+of+recent+exposure.&rft.au=Jacobson%2C+G+A%3BMcLean%2C+S&rft.aulast=Jacobson&rft.aufirst=G&rft.date=2003-06-01&rft.volume=47&rft.issue=4&rft.spage=331&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+occupational+hygiene&rft.issn=00034878&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - wheat; Food supply; Economics; obesity; subsidies; soybeans; corn; Crops; Triticum aestivum; USA ER - TY - JOUR T1 - The Association between Asthma and Allergic Symptoms in Children and Phthalates in House Dust: A Nested Case-Control Study AN - 21371599; 12429550 AB - Global phthalate ester production has increased from very low levels at the end of World War II to approximately 3.5 million metric tons/year. The aim of the present study was to investigate potential associations between persistent allergic symptoms in children, which have increased markedly in developed countries over the past three decades, and the concentration of phthalates in dust collected from their homes. This investigation is a case-control study nested within a cohort of 10,852 children. From the cohort, we selected 198 cases with persistent allergic symptoms and 202 controls without allergic symptoms. A clinical and a technical team investigated each child and her or his environment. We found higher median concentrations of butyl benzyl phthalate (BBzP) in dust among cases than among controls (0.15 vs. 0.12 mg/g dust). Analyzing the case group by symptoms showed that BBzP was associated with rhinitis (p = 0.001) and eczema (p = 0.001), whereas di(2-ethylhexyl) phthalate (DEHP) was associated with asthma (p = 0.022). Furthermore, dose-response relationships for these associations are supported by trend analyses. This study shows that phthalates, within the range of what is normally found in indoor environments, are associated with allergic symptoms in children. We believe that the different associations of symptoms for the three major phthalates-BBzP, DEHP, and di-n-butyl phthalate-can be explained by a combination of chemical physical properties and toxicologic potential. Given the phthalate exposures of children worldwide, the results from this study of Swedish children have global implications. JF - Environmental Health Perspectives AU - Bornehag, Carl-Gustaf AU - Sundell, Jan AU - Weschler, Charles J AU - Sigsgaard, Torben Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1393 EP - 1397 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - phthalates KW - House dust KW - skin diseases KW - Dose-response effects KW - Asthma KW - Respiratory diseases KW - Children KW - Esters KW - Dust KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21371599?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Association+between+Asthma+and+Allergic+Symptoms+in+Children+and+Phthalates+in+House+Dust%3A+A+Nested+Case-Control+Study&rft.au=Bornehag%2C+Carl-Gustaf%3BSundell%2C+Jan%3BWeschler%2C+Charles+J%3BSigsgaard%2C+Torben&rft.aulast=Bornehag&rft.aufirst=Carl-Gustaf&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1393&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - phthalates; House dust; skin diseases; Dose-response effects; Asthma; Respiratory diseases; Esters; Children; Dust ER - TY - JOUR T1 - Relative Fitness of Cry1A-Resistant and -Susceptible Helicoverpa Armigera (Lepidoptera: Noctuidae) on Conventional and Transgenic Cotton AN - 19836026; 6122712 AB - Glasshouse and laboratory experiments were conducted to evaluate the relative fitness of Cry1A-susceptible and laboratory-selected resistant strains of Helicoverpa armigera (Huebner). Life history parameters of H. armigera larvae feeding on young cotton plants showed a significant developmental delay of up to 7 d for the resistant strain compared with the susceptible strain on non-Bacillus thuringiensis (Bt) cotton. This fitness cost was not evident on artificial diet. There was no developmental delay in the F1 hybrid progeny from the reciprocal backcross of the resistant and susceptible strains, indicating that the fitness cost is recessive. In two cohorts tested, survival to pupation of resistant larvae on Bt cotton expressing Cry1Ac was 54 and 51% lower than on non-Bt cotton, whereas all susceptible and F1 larvae tested on Cry1Ac cotton were killed. Mortality of susceptible larvae occurred in the first or second instar, whereas the F1 larvae were able to develop to later instars before dying, demonstrating that resistance is incompletely recessive. The intrinsic rate of increase was reduced by >50% in the resistant strain on Cry1Ac cotton compared with the susceptible strain on non-Bt cotton. There was a significant reduction in the survival of postdiapausal adults from the resistant strain and the F1 strains, indicating that there is a nonrecessive overwintering cost associated with Cry1A resistance in H. armigera. JF - Journal of Economic Entomology AU - Bird, L J AU - Akhurst, R J AD - CSIRO Entomology, GPO Box 1700, Canberra ACT 2601, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1699 EP - 1709 PB - Entomological Society of America VL - 97 IS - 5 SN - 0022-0493, 0022-0493 KW - Noctuid moths KW - Microbiology Abstracts B: Bacteriology; Biotechnology and Bioengineering Abstracts; Entomology Abstracts KW - Fitness KW - Mortality KW - Feeding KW - Helicoverpa armigera KW - Cotton KW - Overwintering KW - Bacillus thuringiensis KW - Artificial diets KW - Survival KW - Pupation KW - Gossypium KW - Transgenic plants KW - Lepidoptera KW - Life history KW - Hybrids KW - Cry1Ac toxin KW - Progeny KW - Noctuidae KW - Toxicity testing KW - J 02410:Animal Diseases KW - W 30925:Genetic Engineering KW - Z 05183:Toxicology & resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19836026?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Economic+Entomology&rft.atitle=Relative+Fitness+of+Cry1A-Resistant+and+-Susceptible+Helicoverpa+Armigera+%28Lepidoptera%3A+Noctuidae%29+on+Conventional+and+Transgenic+Cotton&rft.au=Bird%2C+L+J%3BAkhurst%2C+R+J&rft.aulast=Bird&rft.aufirst=L&rft.date=2004-10-01&rft.volume=97&rft.issue=5&rft.spage=1699&rft.isbn=&rft.btitle=&rft.title=Journal+of+Economic+Entomology&rft.issn=00220493&rft_id=info:doi/10.1043%2F0022-0493%282004%290972.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0022-0493&volume=97&page=1699 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-05-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Fitness; Feeding; Mortality; Cotton; Overwintering; Artificial diets; Survival; Pupation; Transgenic plants; Life history; Hybrids; Cry1Ac toxin; Progeny; Toxicity testing; Helicoverpa armigera; Bacillus thuringiensis; Noctuidae; Gossypium; Lepidoptera DO - http://dx.doi.org/10.1043/0022-0493(2004)097<1699:RFOCAS>2.0.CO;2 ER - TY - JOUR T1 - Female Reproduct Ive Tract Abnormalities in European Hares (Lepus europaeus) in Australia AN - 19770641; 6133461 AB - Populations of European hare (Lepus europaeus) are in decline in Europe, and populations in Australia remain at low densities. Populations are sensitive to size of the breeding stock, which is influenced by fertility in the females. From 1996 to 1999, a total of 272 adult female hares from three Australian populations were dissected and their reproductive systems examined for abnormalities. Cystic endometrial hyperplasia was relatively common and often accompanied by hydrosalpinx. Extrauterine fetuses, neoplasms, pseudopregnancies, and resorptions also were found. However, although pseudopregnancies and resorptions were found in young adults (<12 mo) as well as older hares, conditions possibly causing infertility were almost always in older hares with prevalences up to 46.2%. Only hares with access to known sources of estrogens exhibited pathologic conditions, but sympatric European rabbits (Oryctolagus cuniculus) did not, which is consistent with known difference in responses between the corpora lutea of the two species to exogenous estrogen. Infertility at such a high prevalence could compound and extend the impact of years of low juvenile survival on recruitment. JF - Journal of Wildlife Diseases AU - Stott, Philip AU - Wight, Nicole AD - Department of Animal Science, University of Adelaide SA 5005, Australia and Pest Animal Control Cooperative Research Centre, GPO Box 284, Canberra ACT 2601, Australia, philip.stottadelaide.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 696 EP - 703 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com], [URL:http://www.allenpress.com] VL - 40 IS - 4 SN - 0090-3558, 0090-3558 KW - Ecology Abstracts KW - European hare KW - European rabbit KW - fertility KW - Lepus europaeus KW - Oryctolagus cuniculus KW - phytoestrogen KW - Infertility KW - Estrogens KW - Hyperplasia KW - Endometrium KW - Recruitment KW - Survival KW - Fetuses KW - Pseudopregnancy KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19770641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Diseases&rft.atitle=Female+Reproduct+Ive+Tract+Abnormalities+in+European+Hares+%28Lepus+europaeus%29+in+Australia&rft.au=Stott%2C+Philip%3BWight%2C+Nicole&rft.aulast=Stott&rft.aufirst=Philip&rft.date=2004-10-01&rft.volume=40&rft.issue=4&rft.spage=696&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Diseases&rft.issn=00903558&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Infertility; Endometrium; Hyperplasia; Estrogens; Recruitment; Survival; Fetuses; Pseudopregnancy; Oryctolagus cuniculus; Lepus europaeus ER - TY - JOUR T1 - Assessment of monophyly and taxon affinities within the polychaete clade Terebelliformia (Terebellida) AN - 19392646; 8660721 JF - Journal of the Marine Biological Association of the United Kingdom AU - Glasby, Christopher J AU - Hutchings, Patricia A AU - Hall, Kathryn AD - Museum and Art Gallery of the Northern Territory, GPO Box 4646, Darwin, NT 0801, Australia, chris.glasby@nt.gov.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 961 EP - 971 PB - Cambridge University Press, The Edinburgh Building, VL - 84 IS - 5 SN - 0025-3154, 0025-3154 KW - Ecology Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Ecology KW - Marine KW - Marine invertebrates KW - Terebellida KW - D 04040:Ecosystem and Ecology Studies KW - O 1030:Invertebrates KW - Q1 08243:Taxonomy and morphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19392646?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Marine+Biological+Association+of+the+United+Kingdom&rft.atitle=Assessment+of+monophyly+and+taxon+affinities+within+the+polychaete+clade+Terebelliformia+%28Terebellida%29&rft.au=Glasby%2C+Christopher+J%3BHutchings%2C+Patricia+A%3BHall%2C+Kathryn&rft.aulast=Glasby&rft.aufirst=Christopher&rft.date=2004-10-01&rft.volume=84&rft.issue=5&rft.spage=961&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Marine+Biological+Association+of+the+United+Kingdom&rft.issn=00253154&rft_id=info:doi/10.1017%2FS0025315404010252h LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Marine invertebrates; Ecology; Terebellida; Marine DO - http://dx.doi.org/10.1017/S0025315404010252h ER - TY - JOUR T1 - Creating a new conceptual framework: environment power and society AN - 18020715; 5985101 JF - Ecological Modelling AU - King, R J AD - Good Company Associates, Inc. 816 Congress Avenue, Suite 1100, Austin, TX 78701, USA, rking@goodcompanyassociates.com Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 159 EP - 162 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 178 IS - 1-2 SN - 0304-3800, 0304-3800 KW - Ecology Abstracts KW - Sociology KW - Mathematical models KW - D 04615:Ecology studies - general KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18020715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Creating+a+new+conceptual+framework%3A+environment+power+and+society&rft.au=King%2C+R+J&rft.aulast=King&rft.aufirst=R&rft.date=2004-10-01&rft.volume=178&rft.issue=1-2&rft.spage=159&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.12.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Sociology; Mathematical models DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.12.021 ER - TY - JOUR T1 - Standardized noise annoyance scales in Chinese, Korean and Vietnamese AN - 17880537; 6022109 AB - Internationally standardized annoyance scales are required in order to compare community responses to environmental noises measured in various linguistic regions. ICBEN Team 6 organized an international joint study to establish standardized noise annoyance scales and has developed scales and questions in nine linguistic regions. With the exception of Japan, all of these regions were Euro-American. Thus, it has been necessary to augment the original ICBEN study by utilizing the ICBEN method to construct noise annoyance scales for use in other Asian countries, because noise pollution is becoming an increasingly important environmental issue in these countries. Also, Asian data should be compared internationally with Euro-American data. The present study reports on the use of the ICBEN method to construct annoyance scales in Chinese, Korean and Vietnamese. JF - Journal of Sound and Vibration AU - Yano, T AU - Ma, H AD - Faculty of Engineering, Kumamoto University, Kumamoto 860-8555, Japan, yano@gpo.kumamoto-u.ac.jp Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 583 EP - 588 PB - Academic Press Ltd., 24-28 Oval Rd. London NW1 7DX UK, [mailto:apsubs@acad.com] VL - 277 IS - 3 SN - 0022-460X, 0022-460X KW - annoyance KW - linguistics KW - Chinese KW - Korean KW - Vietnamese KW - Pollution Abstracts KW - Psychology KW - Noise pollution KW - International standardization KW - P 7000:NOISE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880537?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Sound+and+Vibration&rft.atitle=Standardized+noise+annoyance+scales+in+Chinese%2C+Korean+and+Vietnamese&rft.au=Yano%2C+T%3BMa%2C+H&rft.aulast=Yano&rft.aufirst=T&rft.date=2004-10-01&rft.volume=277&rft.issue=3&rft.spage=583&rft.isbn=&rft.btitle=&rft.title=Journal+of+Sound+and+Vibration&rft.issn=0022460X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Psychology; Noise pollution; International standardization DO - http://dx.doi.org/10.1016/j.jsv.2004.03.020 ER - TY - JOUR T1 - Genetic relatedness of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated in south Asia AN - 17797508; 6031639 AB - OBJECTIVES: The aim of the present study was to determine the clonal relationships of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated from south Asia, and S. dysenteriae 1 strains associated with epidemics in 1978, 1984 and 1994. METHODS: The antimicrobial susceptibilities were examined by NCCLS methods. Molecular epidemiological characterization was performed by plasmid profiling, pulsed-field gel electrophoresis (PFGE) and mutation analysis of the quinolone resistance-determining region (QRDR) of gyrA by sequencing. RESULTS: Plasmid patterns of the current ciprofloxacin-resistant strains from India, Nepal and Bangladesh were very similar to those of the 1978, 1984 and 1994 epidemic isolates of S. dysenteriae 1, except for the presence of a new plasmid of -2.6 MDa, which was found in one recent ciprofloxacin-resistant strain isolated in Bangladesh. PFGE analysis showed that the ciprofloxacin- resistant strains isolated in Bangladesh, India and Nepal belonged to a PFGE type (type A), which was possibly related to that of the 1984 and 1994 clone of S. dysenteriae 1, but different from 1978 epidemic strains. The current ciprofloxacin-resistant strains belong to five subtypes (A3-A7), all of which were found in India, but in Bangladesh and Nepal, only A3 existed. Mutation analysis of the QRDR of gyrA revealed that amino acid substitutions at positions 83 and 87 of ciprofloxacin-resistant strains isolated in Bangladesh were similar to those of the strains isolated in Nepal, but different (at position 87) from ciprofloxacin-resistant strains isolated in India. CONCLUSIONS: PFGE and mutation analysis of gyrA showed differences between the current ciprofloxacin- resistant S. dysenteriae 1 strains isolated in south Asia and those associated with epidemics in 1978, 1984 and 1994. JF - Journal of Antimicrobial Chemotherapy AU - Talukder, Kaisar A AU - Khajanchi, Bijay K AU - Islam, MAminul AU - Dutta, Dilip K AU - Islam, Zhahirul AU - Safa, Ashrafus AU - Khan, G Y AU - Alam, Khorshed AU - Hossain, MA AU - Malla, Sarala AU - Niyogi, S K AU - Rahman, Mustafizur AU - Watanabe, Haruo AU - Balakrish Nair, G AU - Sack, David A AD - Enteric Microbiology Laboratory, Laboratory Sciences Division, ICDDR, B: Centre for Health and Population Research, GPO Box-128, Dhaka-1000, Bangladesh Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 730 EP - 734 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 54 IS - 4 SN - 0305-7453, 0305-7453 KW - Microbiology Abstracts B: Bacteriology KW - Ciprofloxacin KW - Amino acid substitution KW - Epidemics KW - Quinolones KW - Pulsed-field gel electrophoresis KW - Plasmids KW - Asia KW - Mutation KW - Antibiotic resistance KW - Shigella dysenteriae KW - J 02795:Antibiotic resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17797508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Antimicrobial+Chemotherapy&rft.atitle=Genetic+relatedness+of+ciprofloxacin-resistant+Shigella+dysenteriae+type+1+strains+isolated+in+south+Asia&rft.au=Talukder%2C+Kaisar+A%3BKhajanchi%2C+Bijay+K%3BIslam%2C+MAminul%3BDutta%2C+Dilip+K%3BIslam%2C+Zhahirul%3BSafa%2C+Ashrafus%3BKhan%2C+G+Y%3BAlam%2C+Khorshed%3BHossain%2C+MA%3BMalla%2C+Sarala%3BNiyogi%2C+S+K%3BRahman%2C+Mustafizur%3BWatanabe%2C+Haruo%3BBalakrish+Nair%2C+G%3BSack%2C+David+A&rft.aulast=Talukder&rft.aufirst=Kaisar&rft.date=2004-10-01&rft.volume=54&rft.issue=4&rft.spage=730&rft.isbn=&rft.btitle=&rft.title=Journal+of+Antimicrobial+Chemotherapy&rft.issn=03057453&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Shigella dysenteriae; Asia; Epidemics; Mutation; Plasmids; Antibiotic resistance; Ciprofloxacin; Quinolones; Pulsed-field gel electrophoresis; Amino acid substitution ER - TY - JOUR T1 - Centrifugation Assisted Agrobacterium tumefaciens-mediated Transformation (CAAT) of embryogenic cell suspensions of banana (Musa spp. Cavendish AAA and Lady finger AAB) AN - 17743325; 6106009 AB - Centrifugation-assisted Agrobacterium-mediated transformation (CAAT) protocol, developed using banana cultivars from two economically important genomic groups (AAA and AAB) of cultivated Musa, is described. This protocol resulted in 25-65 plants/50mg of settled cell volume of embryogenic suspension cells, depending upon the Agrobacterium strain used, and gave rise to hundreds of morphologically normal, transgenic plants in two banana cultivars from the two genomic groups. Development of a highly efficient Agrobacterium-mediated transformation protocol for a recalcitrant species like banana, especially the Cavendish group (AAA) cultivars, required the identification and optimisation of the factors affecting T-DNA delivery and subsequent plant regeneration. We used male-flower-derived embryogenic cell suspensions of two banana cultivars (Cavendish and Lady Finger) and Agrobacterium strains AGL1 and LBA4404, harbouring binary vectors carrying hpt (hygromycin phosphotransferase) and gusA ( beta -glucuronidase) or nptII (neomycin phosphotransferase) and a modified gfp (green fluorescent protein) gene in the T-DNA, to investigate and optimise T-DNA delivery and tissue culture variables. Factors evaluated included pre-induction of Agrobacterium, conditions and media used for inoculation and co-cultivation, and the presence of acetosyringone and Pluronic F68 in the co-cultivation media. One factor that led to a significant enhancement in transformation frequency was the introduction of a centrifugation step during co-cultivation. Post co-cultivation liquid-media wash and recovery step helped avoid Agrobacterium overgrowth on filters supporting suspension culture cells. Marker-gene expression and molecular analysis demonstrated that transgenes integrated stably into the banana genome. T-DNA:banana DNA boundary sequences were amplified and sequenced in order to study the integration profile. JF - Molecular Breeding AU - Khanna, H AU - Becker, D AU - Kleidon, J AU - Dale, J AD - Plant Biotechnology Program, Science Research Centre, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia, h.khanna@qut.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 239 EP - 252 PB - Kluwer Academic Publishers VL - 14 IS - 3 SN - 1380-3743, 1380-3743 KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Bioengineering Abstracts; Genetics Abstracts KW - Transformation KW - Nucleotide sequence KW - Transgenic plants KW - Gene expression KW - Agrobacterium tumefaciens KW - Centrifugation KW - Musa KW - T-DNA KW - Cell suspensions KW - Reporter gene KW - Morphology KW - W2 32065:Plants KW - G 07354:Dicotyledons (crops) KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17743325?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Remote+Sensing+of+Environment&rft.atitle=Decomposition+of+vegetation+cover+into+woody+and+herbaceous+components+using+AVHRR+NDVI+time+series&rft.au=Lu%2C+H%3BRaupach%2C+M+R%3BMcVicar%2C+T+R%3BBarrett%2C+D+J&rft.aulast=Lu&rft.aufirst=H&rft.date=2003-06-01&rft.volume=86&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Remote+Sensing+of+Environment&rft.issn=00344257&rft_id=info:doi/10.1016%2FS0034-4257%2803%2900054-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Musa; Agrobacterium tumefaciens; Cell suspensions; Transformation; Centrifugation; Morphology; Transgenic plants; Reporter gene; Gene expression; T-DNA; Nucleotide sequence DO - http://dx.doi.org/10.1023/B:MOLB.0000047771.34186.e8 ER - TY - JOUR T1 - Tribology Approach to the Engineering and Study of Articular Cartilage AN - 17703351; 6111523 AB - This study has been based on the assumption that articular motion is an important aspect of mechanotransduction in synovial joints. For this reason a new bioreactor concept, able to reproduce joint kinematics more closely, has been designed. The prototype consists of a rotating scaffold and/or cartilage pin, which is pressed onto an orthogonally rotating ball. By oscillating pin and ball in phase difference, elliptical displacement trajectories are generated that are similar to the motion paths occurring in vivo. Simultaneously, dynamic compression may be applied with a linear actuator, while two-step-motors generate the rotation of pin and ball. The whole apparatus is placed in an incubator. The control station is located outside. Preliminary investigations at the gene expression level demonstrated promising results. Compared with free-swelling control and/or simply compression-loaded samples, chondrocyte-seeded scaffolds as well as nasal cartilage explants exposed to interface motion both showed elevated levels of cartilage oligomeric matrix protein mRNA. The final design of the bioreactor will include four individual stations in line, which will facilitate the investigation of motion-initiated effects at the contacting surfaces in more detail. JF - Tissue Engineering AU - Wimmer, MA AU - Grad, S AU - Kaup, T AU - Haenni, M AU - Schneider, E AU - Gogolewski, S AU - Alini, M AD - Department of Orthopedic Surgery, Rush University Medical Center, 1653 W. Congress Pkwy, Suite 1417, Chicago, IL 60612, USA, markus_a_wimmer@rush.edu Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1436 EP - 1445 VL - 10 IS - 9-10 SN - 1076-3279, 1076-3279 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Cartilage oligomeric matrix protein KW - Kinematics KW - Tissue engineering KW - scaffolds KW - Compression KW - Joints KW - Gene expression KW - Bioreactors KW - Cartilage (articular) KW - Explants KW - Mechanotransduction KW - W 30965:Miscellaneous, Reviews KW - W3 33220:Cell culture KW - W4 110:Biomedical Materials & Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17703351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tissue+Engineering&rft.atitle=Tribology+Approach+to+the+Engineering+and+Study+of+Articular+Cartilage&rft.au=Wimmer%2C+MA%3BGrad%2C+S%3BKaup%2C+T%3BHaenni%2C+M%3BSchneider%2C+E%3BGogolewski%2C+S%3BAlini%2C+M&rft.aulast=Wimmer&rft.aufirst=MA&rft.date=2004-10-01&rft.volume=10&rft.issue=9-10&rft.spage=1436&rft.isbn=&rft.btitle=&rft.title=Tissue+Engineering&rft.issn=10763279&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - scaffolds; Bioreactors; Joints; Kinematics; Compression; Mechanotransduction; Gene expression; Cartilage (articular); Explants; Tissue engineering; Cartilage oligomeric matrix protein ER - TY - JOUR T1 - River patterns and their meaning AN - 17690571; 6046860 AB - Rivers are largely responsible for shaping the Earth's continental landscapes. River patterns, the spatial arrangements of channels in the landscape, are determined by slope and structure. At site and sector scale, channel morphology varies spatially and in time, but river patterns and drainage texture, or the frequency of stream lines per unit area, together determine the intricacy, or otherwise, of topography. Most river patterns evolve through natural selection. Slope induces the formation of such patterns as parallel, radial and distributary, while structure produces straight, angular, trellis and annular arrangements. Once established, patterns tend to persist. Nevertheless, at many sites the usual patterns have been disturbed and patterns that are anomalous in terms of slope and structure have been produced by diversion, tectonism, volcanism, glaciation, mass movements, and human activities; by antecedence, superimposition, inheritance or underprinting; by the persistence of deeply eroding rivers which encounter alien structures; and by climatic change. River patterns provide clues to underlying structure and to the chronology of events. They have also proved significant in the search for minerals. JF - Earth-Science Reviews AU - Twidale, C R AD - Geology and Geophysics, School of Earth and Environmental Sciences, The University of Adelaide, G.P.O. Box 498, Adelaide, South Australia 5005, Australia, rowl.twidale@adelaide.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 159 EP - 218 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 67 IS - 3-4 SN - 0012-8252, 0012-8252 KW - Meteorological & Geoastrophysical Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - Q2 02263:Topography and morphology KW - M2 556.5:Surface Water Hydrology (556.5) KW - SW 0835:Streamflow and runoff UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17690571?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Earth-Science+Reviews&rft.atitle=River+patterns+and+their+meaning&rft.au=Twidale%2C+C+R&rft.aulast=Twidale&rft.aufirst=C&rft.date=2004-10-01&rft.volume=67&rft.issue=3-4&rft.spage=159&rft.isbn=&rft.btitle=&rft.title=Earth-Science+Reviews&rft.issn=00128252&rft_id=info:doi/10.1016%2Fj.earscirev.2004.03.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.earscirev.2004.03.001 ER - TY - JOUR T1 - Effects Of Imposed Sterility On Movement Patterns Of Female Ricefield Rats AN - 17642864; 6456973 AB - Fertility control is used for the management of overabundant species. If sterilized individuals abandon their territories, fertile immigrants may invade and compromise fertility control. In southeast Asia, ricefield rats (Rattus argentiventer) can cause significant pre-harvest damage to lowland irrigated rice fields and may be a prime target for the use of fertility control. However, little is known about the behavioral response of ricefield rats to sterilization. We tested the effects of surgical and hormonal sterilization on movement patterns of female ricefield rats in rice fields in West Java, Indonesia. We found that surgically sterilized rats had the largest home ranges (1.8 plus or minus 0.1 ha), about twice the size of home ranges of hormonally sterilized rats and fertile rats. Hormonally sterilized rats tended to lose their territories-indicated by a high rate of burrow relocation-although hormonally sterilized, surgically sterilized, and fertile rats did not leave the ricefield system. We found no difference in survival rate and preference for refuge habitats between sterilized and fertile rats. Although changes in movement patterns after sterilization occurred, these changes are unlikely to affect the success of fertility control in ricefield rats negatively because sterilized rats remained in the ricefield system throughout the breeding period. JF - Journal of Wildlife Management AU - Jacob, J AU - Matulessy, J AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT, 2601, Australia, and Pest Animal Control Cooperative Research Centre, GPO Box 284, Canberra, ACT, 2601, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1138 EP - 1144 PB - The Wildlife Society VL - 68 IS - 4 SN - 0022-541X, 0022-541X KW - Ecology Abstracts KW - D 04700:Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17642864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Management&rft.atitle=Effects+Of+Imposed+Sterility+On+Movement+Patterns+Of+Female+Ricefield+Rats&rft.au=Jacob%2C+J%3BMatulessy%2C+J&rft.aulast=Jacob&rft.aufirst=J&rft.date=2004-10-01&rft.volume=68&rft.issue=4&rft.spage=1138&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Management&rft.issn=0022541X&rft_id=info:doi/10.2193%2F0022-541X%282004%290682.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0022-541X&volume=68&issue=4&page=1138 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-10-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.2193/0022-541X(2004)068[1138:EOISOM]2.0.CO;2 ER - TY - JOUR T1 - The Impact Of Sterilized Females On Enclosed Populations Of Ricefield Rats AN - 17638140; 6456972 AB - For the sustainable management of small mammals, fertility control may be used in the future. Little is known about what proportions of females need to be sterilized to achieve an impact on population size and what compensatory processes may act on the population level. We tested the impact of surgical sterilization of zero, 25, 50, and 75% of females on the population dynamics and demography of enclosed populations of ricefield rats (Rattus argentiventer) and damage to rice crop. Sterilizing 50% of female founders (6 of 12) decreased population size at the end of the breeding season by about 50%. We used a simulation model, based on the breeding biology of the ricefield rat in the field and in the control enclosures, to generate the expected dynamics of the enclosure populations. The results suggested that compensation occurred in the enclosures where 75% of female founders (9 of 12) had been sterilized. We detected a slight tendency for 50% higher numbers of recent uterine scars in fertile founder females in the 50% and 75% treatments versus 25% treatments and controls (P = 0.198). The primary demographic mechanism for compensation was higher survival of young rats in enclosures where 75% of females were sterilized. However, compensation only partially offset the decrease in population size. We found no conclusive evidence that the reproductive output of F sub(1) generation females was higher when large proportions of female founders were sterilized. Early in the breeding season, the per capita damage to rice plants in populations without sterilized ricefield rats was increased. Our results suggest that the sterilization of >50% of females in ricefield rat populations can reduce rat population growth and rat damage to rice crops. JF - Journal of Wildlife Management AU - Jacob, J AU - Aini herawati, N AU - Davis, SA AU - Singleton, G R AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT, 2601, Australia, and Pest Animal Control Cooperative Research Centre, GPO Box 284, Canberra, ACT, 2601, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1130 EP - 1137 PB - The Wildlife Society VL - 68 IS - 4 SN - 0022-541X, 0022-541X KW - Sustainability Science Abstracts; Ecology Abstracts KW - D 04700:Management KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17638140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Management&rft.atitle=The+Impact+Of+Sterilized+Females+On+Enclosed+Populations+Of+Ricefield+Rats&rft.au=Jacob%2C+J%3BAini+herawati%2C+N%3BDavis%2C+SA%3BSingleton%2C+G+R&rft.aulast=Jacob&rft.aufirst=J&rft.date=2004-10-01&rft.volume=68&rft.issue=4&rft.spage=1130&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Management&rft.issn=0022541X&rft_id=info:doi/10.2193%2F0022-541X%282004%290682.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0022-541X&volume=68&issue=4&page=1130 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.2193/0022-541X(2004)068[1130:TIOSFO]2.0.CO;2 ER - TY - JOUR T1 - Beyond Modelling: Linking Models with GIS for Flood Risk Management AN - 17604722; 6039266 AB - Spatially explicit hydrodynamic flood models can play an important role in natural hazard risk reduction. A key element of these models that make them suitable for risk reduction is the ability to provide time-series inundation information about the onset, duration and passing of a hazard event. Such information can be critical for landuse planning, for mapping evacuation egress routes, and for locating suitable emergency shelters to name only a few risk treatments. This research contends that a barrier to effective risk reduction is providing disaster managers with access to model results in a structured and flexible framework that allows consequences of different hazard scenarios to be assessed and mapped. To address these limitations, a framework has been developed that links a commercial relational database management system with a GIS-based decision support system. The framework utilises industry standard data exchange protocols and results in efficient time-series hazard data management. A case study based in Cairns, in far-north coastal Australia is presented to illustrate how the system has been developed. Results show that the framework reduces data volumes significantly, while making pre-run modelled inundation results rapidly accessible to disaster managers. Of note is the ability of the framework to present results in terms of risk to buildings, roads and other spatial features in urban regions, and to provide answers to relatively complex risk questions. JF - Natural Hazards AU - Zerger, A AU - Wealands, S AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT 2601, Australia, andre.zerger@csiro.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 191 EP - 208 PB - Kluwer Academic Publishers VL - 33 IS - 2 SN - 0921-030X, 0921-030X KW - Meteorological & Geoastrophysical Abstracts; Health & Safety Science Abstracts; Water Resources Abstracts; Risk Abstracts KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - SW 2060:Effects on water of human nonwater activities KW - R2 23030:Natural hazards KW - M2 556.16:Runoff (556.16) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17604722?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Natural+Hazards&rft.atitle=Beyond+Modelling%3A+Linking+Models+with+GIS+for+Flood+Risk+Management&rft.au=Zerger%2C+A%3BWealands%2C+S&rft.aulast=Zerger&rft.aufirst=A&rft.date=2004-10-01&rft.volume=33&rft.issue=2&rft.spage=191&rft.isbn=&rft.btitle=&rft.title=Natural+Hazards&rft.issn=0921030X&rft_id=info:doi/10.1023%2FB%3ANHAZ.0000037040.72866.92 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1023/B:NHAZ.0000037040.72866.92 ER - TY - JOUR T1 - Proclivity and effectiveness in gall defence by soldiers in five species of gall-inducing thrips: benefits of morphological caste dimorphism in two species (Kladothrips intermedius and K. habrus) AN - 17505925; 6282874 AB - The essence of eusociality is a trade-off between producing one's own offspring and helping collateral kin via such activities as defence, foraging and brood rearing. This trade-off often involves morphological differences between 'helper' and 'reproductive' castes, but the advantages, correlates and phylogenetic context of morphological caste differentiation have seldom been analysed. Six species of Australian gall-inducing thrips on Acacia show morphological polymorphism. One morph, referred to as a soldier, has reduced wings and antennae but greatly enlarged fore-femora, which are thought to be adaptations for gall defence. The other, dispersing morph, has fully developed wings and relatively slight fore-femora. Here, we quantify the defensive behaviour of soldier morphs, and compare soldier and foundresses, using behavioural assays designed to measure proclivity to attack kleptoparasites (specialised invaders in the genus Koptothrips) and effectiveness in killing them. In all five species investigated, soldiers were able to kill Koptothrips. Moreover, the effectiveness of soldiers was relatively high in the more-derived species in the phylogeny of the clade, Kladothrips intermedius, K. habrus and K. waterhousei. Soldiers of K. intermedius and K. habrus also killed kleptoparasites more effectively than did foundresses, and K. habrus soldiers exhibited higher proclivity to attack than did foundresses. Data from naturally invaded galls demonstrate that soldiers in the field do kill Koptothrips, and vice versa. These results show that soldiers of Australian gall thrips are motivated and effective for gall defence. JF - Behavioral Ecology and Sociobiology AU - Perry, S P AU - Chapman, T W AU - Schwarz, M P AU - Crespi, B J AD - Flinders University, GPO Box 2100, SA 5001, Adelaide, Australia, simp0082@flinders.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 602 EP - 610 PB - Springer-Verlag (Berlin), Heidelberger Platz 3 Berlin 14197 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 56 IS - 6 SN - 0340-5443, 0340-5443 KW - Animal Behavior Abstracts; Ecology Abstracts; Entomology Abstracts KW - Canker KW - Castes KW - Acacia KW - Caste differentiation KW - Dimorphism KW - Phylogeny KW - Wings KW - Brood rearing KW - Soldiers KW - D 04659:Insects KW - Z 05198:Defense & offense KW - Y 25503:Insects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17505925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Behavioral+Ecology+and+Sociobiology&rft.atitle=Proclivity+and+effectiveness+in+gall+defence+by+soldiers+in+five+species+of+gall-inducing+thrips%3A+benefits+of+morphological+caste+dimorphism+in+two+species+%28Kladothrips+intermedius+and+K.+habrus%29&rft.au=Perry%2C+S+P%3BChapman%2C+T+W%3BSchwarz%2C+M+P%3BCrespi%2C+B+J&rft.aulast=Perry&rft.aufirst=S&rft.date=2004-10-01&rft.volume=56&rft.issue=6&rft.spage=602&rft.isbn=&rft.btitle=&rft.title=Behavioral+Ecology+and+Sociobiology&rft.issn=03405443&rft_id=info:doi/10.1007%2Fs00265-004-0811-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Acacia; Soldiers; Canker; Castes; Wings; Brood rearing; Caste differentiation; Dimorphism; Phylogeny DO - http://dx.doi.org/10.1007/s00265-004-0811-8 ER - TY - JOUR T1 - Drug Delivery Across the Blood-Brain Barrier AN - 17437814; 6538398 AB - The brain is protected and isolated from the general circulation by a highly efficient blood-brain barrier. This is characterised by relatively impermeable endothelial cells with tight junctions, enzymatic activity and active efflux transport systems. Consequently the blood-brain barrier is designed to permit selective transport of molecules that are essential for brain function. This creates a considerable challenge for the treatment of central nervous system diseases requiring therapeutic levels of drug to enter the brain. Some small lipophilic drugs diffuse across the blood-brain barriersufficiently well to be efficacious. However, many potentially useful drugs are excluded. This review provides an insight into the current research into technologies to target small molecules, peptides and proteins to the brain. A brief review of the nature of the blood-brain barrier and its transport mechanisms is provided. Strategies to target and improve transport across the blood-brain barrier include the prodrug-lipidisation approach, sequential metabolism chemical delivery systems, drug-vectors, liposomes and nanoparticles. Included is the discussion of techniques to minimise clearance from the circulation by the reticuloendothelial system in order to extend circulation residence time and optimise the opportunity for interaction between the drug delivery system and the blood-brain barrier. JF - Current Drug Delivery AU - Chen, Y AU - Dalwadi, G AU - Benson, HAE AD - Western Australian Biomedical Research Institute, School of Pharmacy, Curtin University of Technology, GPO Box U1987, Perth, Western Australia 6845, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 361 EP - 376 VL - 1 IS - 4 SN - 1567-2018, 1567-2018 KW - Biotechnology and Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Endothelial cells KW - Drug delivery KW - Tight junctions KW - Blood-brain barrier KW - Reviews KW - Central nervous system diseases KW - Brain KW - Reticuloendothelial system KW - Liposomes KW - nanoparticles KW - Lipophilic KW - W3 33388:Drug delivery vehicles (liposomes, cochleates, microspheres) KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17437814?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+Drug+Delivery&rft.atitle=Drug+Delivery+Across+the+Blood-Brain+Barrier&rft.au=Chen%2C+Y%3BDalwadi%2C+G%3BBenson%2C+HAE&rft.aulast=Chen&rft.aufirst=Y&rft.date=2004-10-01&rft.volume=1&rft.issue=4&rft.spage=361&rft.isbn=&rft.btitle=&rft.title=Current+Drug+Delivery&rft.issn=15672018&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Blood-brain barrier; Brain; Drug delivery; Reviews; Central nervous system diseases; nanoparticles; Endothelial cells; Lipophilic; Liposomes; Tight junctions; Reticuloendothelial system ER - TY - JOUR T1 - Environmental Protection Issues in the 108th Congress AN - 14722005; 10673298 AB - Key environmental protection issues that are receiving attention in the 108th Congress are surveyed. At the start of the second session, Congress completed consideration of a consolidated appropriations Act which provides $8.27 billion for EPA in FY2004. The Administration had requested $7.79 billion, $577 million less than the FY2004 appropriations. The 108th Congress has taken, but in most cases not completed, action on legislation to address leaking underground storage tanks that may contaminate water supplies, security issues related to wastewater treatment and chemical facilities, environmental issues in comprehensive energy legislation, and expanding authority for an EPA ombudsman. JF - US Congressional Research Service Report IB10115 AU - Fletcher, Susan AU - Isler, Margaret Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - SUPERFUND KW - LEGISLATION, FEDERAL KW - EPA, FEDERAL KW - HAZARDOUS WASTE MANAGEMENT KW - CLEAN AIR ACT AMENDMENTS 90 KW - CLEAN WATER ACT KW - UNDERGROUND FUEL STORAGE KW - POLLUTION CONTROL FINANCING KW - ENV PROBLEMS, GENERAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14722005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10115&rft.atitle=Environmental+Protection+Issues+in+the+108th+Congress&rft.au=Fletcher%2C+Susan%3BIsler%2C+Margaret&rft.aulast=Fletcher&rft.aufirst=Susan&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10115&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SUPERFUND; LEGISLATION, FEDERAL; UNDERGROUND FUEL STORAGE; HAZARDOUS WASTE MANAGEMENT; EPA, FEDERAL; CLEAN AIR ACT AMENDMENTS 90; CLEAN WATER ACT; POLLUTION CONTROL FINANCING; ENV PROBLEMS, GENERAL ER - TY - JOUR T1 - Western Water Resource Issues AN - 14721768; 10673302 AB - Pressures on water resources are mounting in the western US, where agricultural needs are often in direct conflict with urban needs as well as with water demand for threatened and endangered species and recreation. The 108th Congress is considering many western water resource issues, and new developments involving California's allocation of Colorado River water has spurred additional oversight of related topics, such as progress in restoring the Salton Sea. In September 2004, the Senate passed a bill to authorize implementation of the CALFED Bay-Delta Program, a federal and state effort to coordinate water management and ecosystem restoration activities at the confluence of the Sacramento and San Joaquin Rivers and San Francisco Bay. JF - US Congressional Research Service Report IB10019 AU - Cody, Betsy A AU - Sheikh, Pervaze A Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - MULTIPLE USE, WATER KW - LEGISLATION, FEDERAL KW - WATER SUPPLY KW - INTERBASIN WATER TRANSFER KW - RIVER BASINS KW - WATER RESOURCES MANAGEMENT KW - WATER LAW KW - IRRIGATION KW - ENV RESTORATION KW - URBAN WATER RESOURCES KW - UNITED STATES WEST KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14721768?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Materials+Science%3A+Materials+in+Medicine&rft.atitle=Calcium+phosphate+nucleation+on+surface-modified+PTFE+membranes&rft.au=GrOendahl%2C+Lisbeth%3BCardona%2C+Francisco%3BChiem%2C+Khang%3BWentrup-Byrne%2C+Edeline%3BBostrom%2C+Thor&rft.aulast=GrOendahl&rft.aufirst=Lisbeth&rft.date=2003-06-01&rft.volume=14&rft.issue=6&rft.spage=503&rft.isbn=&rft.btitle=&rft.title=Journal+of+Materials+Science%3A+Materials+in+Medicine&rft.issn=09574530&rft_id=info:doi/10.1023%2FA%3A1023403929496 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV RESTORATION; MULTIPLE USE, WATER; LEGISLATION, FEDERAL; URBAN WATER RESOURCES; INTERBASIN WATER TRANSFER; WATER SUPPLY; RIVER BASINS; WATER RESOURCES MANAGEMENT; UNITED STATES WEST; IRRIGATION; WATER LAW ER - TY - JOUR T1 - Clean Air Act Issues in the 108th Congress AN - 14719575; 10673301 AB - Prominent air quality issues of interest in the 108th Congress are surveyed. Major debate has focused on coal-fired power plant emissions and EPA's controversial proposed standards for mercury, sulfur dioxide, and nitrogen oxides emissions from these plants. Legislation has also been submitted to replace numerous Clean Air Act requirements with a national cap and trade program for these pollutants. The Senate approved a bill directing NAS to conduct a study of changes proposed by EPA to streamline New Source Review Requirements. Congressional attention to emission standards for small engines, transportation conformity, Clear Skies legislation, and designation of nonattainment areas for new particulate matter and 8-h ozone standards is also noted. JF - US Congressional Research Service Report IB10107 AU - McCarthy, James E Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - POWER PLANTS, COAL FIRED KW - AIR QUALITY PROGRAMS KW - EMISSION CONTROL STANDARDS KW - SULFUR DIOXIDE KW - LEGISLATION, FEDERAL KW - EPA, FEDERAL KW - AIR QUALITY STANDARDS, SOURCE KW - PARTICULATES KW - OZONE KW - NITROGEN OXIDES KW - POWER PLANT EMISSION CONTROL KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14719575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10107&rft.atitle=Clean+Air+Act+Issues+in+the+108th+Congress&rft.au=McCarthy%2C+James+E&rft.aulast=McCarthy&rft.aufirst=James&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10107&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; POWER PLANTS, COAL FIRED; AIR QUALITY PROGRAMS; LEGISLATION, FEDERAL; NITROGEN OXIDES; EMISSION CONTROL STANDARDS; AIR QUALITY STANDARDS, SOURCE; EPA, FEDERAL; POWER PLANT EMISSION CONTROL; MERCURY; OZONE; PARTICULATES ER - TY - JOUR T1 - Clean Water Act Issues in the 108th Congress AN - 14719448; 10673300 AB - In 2002, Congressional committees approved bills to reauthorize wastewater infrastructure funding under the Clean Water Act, but no further action occurred. This issue has also received attention in the 108th Congress. In October 2004, the Senate Environment and Public Works Committee reported legislation to authorize $20 billion in funding for clean water infrastructure. While prospects for further action during the 108th Congress are uncertain, several issues under the Act could be the focus of debate, including revisions to the total maximum daily load program, wetlands provisions, and pollution from confined animal feeding operations. JF - US Congressional Research Service Report IB10108 AU - Copeland, Claudia Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - LEGISLATION, FEDERAL KW - LIVESTOCK FEEDLOT RUNOFF KW - CLEAN WATER ACT KW - WATER POLLUTION CONTROL FINANCING KW - WASTEWATER TREATMENT KW - WATER QUALITY STANDARDS KW - WETLANDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14719448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10108&rft.atitle=Clean+Water+Act+Issues+in+the+108th+Congress&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10108&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - WATER POLLUTION CONTROL FINANCING; WASTEWATER TREATMENT; LEGISLATION, FEDERAL; LIVESTOCK FEEDLOT RUNOFF; CLEAN WATER ACT; WATER QUALITY STANDARDS; WETLANDS ER - TY - JOUR T1 - Water Quality: Implementing the Clean Water Act AN - 14718062; 10673297 AB - Recent developments in the implementation of the Clean Water Act Amendments of 1987 are surveyed. Impacts and implementation of requirements under current law for states to develop total maximum daily loads to restore pollution-affected waters are covered, as is progress in implementing nonpoint pollution management provisions. States are devising management policies describing methods that will be applied to reduce such pollution, which may be responsible for as much as 50% of remaining water quality problems in the US. Implementation of these measures is hindered by limited resources, and EPA has adopted program guidance intended to afford states more flexibility and to speed up progress in this arena. JF - US Congressional Research Service Report IB89102 AU - Copeland, Claudia Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - CLEAN WATER ACT AMENDMENTS 87 KW - LAW ENFORCEMENT, FEDERAL KW - STATE AND LOCAL ENV PROGRAMS KW - WATER POLLUTION CONTROL FINANCING KW - NONPOINT SOURCE POLLUTION KW - WATER QUALITY STANDARDS KW - WETLANDS KW - WATER QUALITY PROGRAMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718062?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB89102&rft.atitle=Water+Quality%3A+Implementing+the+Clean+Water+Act&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB89102&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - WATER POLLUTION CONTROL FINANCING; STATE AND LOCAL ENV PROGRAMS; CLEAN WATER ACT AMENDMENTS 87; NONPOINT SOURCE POLLUTION; LAW ENFORCEMENT, FEDERAL; WATER QUALITY STANDARDS; WETLANDS; WATER QUALITY PROGRAMS ER - TY - JOUR T1 - Wisconsin's Environmental Public Health Tracking Network: Information Systems Design for Childhood Cancer Surveillance AN - 14710422; 10670453 AB - An information technology platform is described, which is in development to support environmental public-health tracking in Wisconsin. Called Wisconsin's Public Health Information Network, it is aimed at rapid, state-of-the-art technology transfer from the university to government, business, and all citizens of the state. Described specifically is the childhood cancer surveillance, which utilizes statewide health and environmental monitoring information and nationally available environmental and demographic datasets. System specifications required the support of two surveillance tracks-hypothesis generation and hypothesis testing-to provide a more complete view of environmental disease risk. JF - Environmental Health Perspectives AU - Hanrahan, Lawrence P AU - Anderson, Henry A AU - Busby, Brian AU - Bekkedal, Marni AU - Sieger, Thomas AU - Stephenson, Laura AU - Knobeloch, Lynda Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1434 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - PUBLIC HEALTH KW - INFORMATION SYSTEMS, ENV KW - MEDICAL SURVEILLANCE KW - WISCONSIN KW - PATHOLOGY, CHILDREN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Chemical+Ecology&rft.atitle=Effects+of+two+plant+secondary+metabolites%2C+cineole+and+gallic+acid%2C+on+nightly+feeding+patterns+of+the+common+brushtail+possum&rft.au=Wiggins%2C+N+L%3BMcArthur%2C+C%3BMcLean%2C+S%3BBoyle%2C+R&rft.aulast=Wiggins&rft.aufirst=N&rft.date=2003-06-01&rft.volume=29&rft.issue=6&rft.spage=1447&rft.isbn=&rft.btitle=&rft.title=Journal+of+Chemical+Ecology&rft.issn=00980331&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - INFORMATION SYSTEMS, ENV; CANCER RISK; MEDICAL SURVEILLANCE; PATHOLOGY, CHILDREN; WISCONSIN; PUBLIC HEALTH ER - TY - JOUR T1 - Arsenic on the Hands of Children After Playing in Playgrounds AN - 14709552; 10670442 AB - At 16 playgrounds in Edmonton, AB, Canada, the amount of arsenic on the hands of children in contact with chromated copper arsenate (CCA)-treated wood structures and sand was quantified. Half of the playgrounds were constructed with CCA-treated wood, and the other were used as controls. After play, the children's hands were washed, and the As concentration on the hands and in the sand was measured in the washing. No significant difference was found between CCA and non-CCA playgrounds in terms of As concentrations in the sand/soil samples, and the As concentrations in all samples were below the Canadian guideline value of 12 mg/kg. A difference was found in the As concentration in the washings of children's hands, with the total amount of As and As in the sand collected from children's hands significantly higher for the CCA group than for the non-CCA group. The difference was dominated by the soluble As in the hand-washing water, which was approximately fivefold higher in the CCA group than in the non-CCA group. The maximum among of As on the children's hands, however, was less than 4 mu g, which is lower than the average daily intake of As from water and food. JF - Environmental Health Perspectives AU - Kwon, Elena AU - Zhang, Hongquan AU - Wang, Zongwen AU - Jhangri, Gian S AU - Lu, Xiufen AU - Fok, Nelson AU - Gabos, Stephan Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1375 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - ALBERTA KW - ARSENIC KW - RECREATION, OUTDOOR, LAND KW - SOIL ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Arsenic+on+the+Hands+of+Children+After+Playing+in+Playgrounds&rft.au=Kwon%2C+Elena%3BZhang%2C+Hongquan%3BWang%2C+Zongwen%3BJhangri%2C+Gian+S%3BLu%2C+Xiufen%3BFok%2C+Nelson%3BGabos%2C+Stephan&rft.aulast=Kwon&rft.aufirst=Elena&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1375&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; ALBERTA; RECREATION, OUTDOOR, LAND; ARSENIC; SOIL ANALYSIS ER - TY - JOUR T1 - Drinking-Water Nitrate, Methemoglobinemia, and Global Burden of Disease: a Discussion AN - 14709094; 10670441 AB - The Global Burden of Disease project, conducted under the auspices of WHO, is attempting to quantify and compare the level of illness at both world and regional levels. One such disease is nitrate-related drinking-water methemoglobinemia, which is a disease mainly of young children. Methemoglobin is formed when nitrite oxidizes the ferrous iron in hemoglobin to the ferric form, and the condition is characterized by cyanosis, stupor, and cerebral anoxia, as methemoglobin cannot bind oxygen. A review is presented of the role of nitrates in the causation of methemoglobinemia, citing the limited data that have been published. A number of authors, however, are questioning the simple association between NO sub(3) and infant methemoglobinemia, proposing instead that NO sub(3) is a cofactor in one of several causes of the disease. JF - Environmental Health Perspectives AU - Fewtrell, Lorna Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1371 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DISEASES AND DISORDERS KW - NITRATES KW - WATER, DRINKING KW - METHEMOGLOBINEMIA KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709094?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Drinking-Water+Nitrate%2C+Methemoglobinemia%2C+and+Global+Burden+of+Disease%3A+a+Discussion&rft.au=Fewtrell%2C+Lorna&rft.aulast=Fewtrell&rft.aufirst=Lorna&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1371&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; NITRATES; METHEMOGLOBINEMIA; WATER, DRINKING; LITERATURE SURVEYS ER - TY - JOUR T1 - Outdoor, Indoor, and Personal Exposure to VOCs in Children AN - 14705173; 10670444 AB - As part of the School Health Initiative: Environment, Learning, and Disease Study in Minneapolis, MN, the distribution of exposures to common VOCs was measured in personal air and in three primary microenvironments where children spend most of their time. Measurements were made outdoors and indoors at school and home for an ethnically and racially diverse sample of inner-city children. For most of the compounds, indoor residences had the highest VOC concentrations, followed by personal air, while outdoor and school microenvironments were relatively small contributors to personal exposure. Personal air concentrations were slightly lower than indoor home concentrations for all compounds except p-dichlorobenzene. In the home, adult tobacco use was associated with elevated styrene and benzene personal exposures, and use of cleaning supplies was associated with higher d-limonene, p-dichlorobenzene, and trichloroethylene personal exposures. African Americans had higher chloroform exposures; Hispanics had higher p-dichlorobenzene and beta -pinene exposures; Somalis had higher beta -pinene exposures; and Southeast Asians had higher d-limonene and p-dichlorobenzene exposures. JF - Environmental Health Perspectives AU - Adgate, John L AU - Church, Timothy R AU - Ryan, Andrew D AU - Ramachandran, Gurumurthy AU - Fredrickson, Ann L AU - Stock, Thomas H AU - Morandi, Maria T Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1386 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SCHOOLS KW - VOLATILE ORGANIC COMPOUNDS KW - URBAN ATMOSPHERE KW - AIR POLLUTION, INDOOR KW - RACIAL COMPARISONS KW - INNER CITY KW - MINNESOTA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Outdoor%2C+Indoor%2C+and+Personal+Exposure+to+VOCs+in+Children&rft.au=Adgate%2C+John+L%3BChurch%2C+Timothy+R%3BRyan%2C+Andrew+D%3BRamachandran%2C+Gurumurthy%3BFredrickson%2C+Ann+L%3BStock%2C+Thomas+H%3BMorandi%2C+Maria+T&rft.aulast=Adgate&rft.aufirst=John&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1386&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 43 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SCHOOLS; AIR POLLUTION, INDOOR; INNER CITY; RACIAL COMPARISONS; MINNESOTA; VOLATILE ORGANIC COMPOUNDS; URBAN ATMOSPHERE ER - TY - JOUR T1 - National Environmental Public Health Tracking Program: Bridging the Information Gap AN - 14705163; 10670448 JF - Environmental Health Perspectives AU - MaGeehin, Michael A AU - Qualters, Judith R AU - Niskar, Amanda Sue Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1409 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - INFORMATION SYSTEMS, ENV KW - MEDICAL SURVEILLANCE KW - PUBLIC HEALTH KW - MONITORING, ENV KW - ENV ACTION, FEDERAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=National+Environmental+Public+Health+Tracking+Program%3A+Bridging+the+Information+Gap&rft.au=MaGeehin%2C+Michael+A%3BQualters%2C+Judith+R%3BNiskar%2C+Amanda+Sue&rft.aulast=MaGeehin&rft.aufirst=Michael&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1409&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - INFORMATION SYSTEMS, ENV; MEDICAL SURVEILLANCE; MONITORING, ENV; PUBLIC HEALTH; ENV ACTION, FEDERAL ER - TY - JOUR T1 - Application of Benzo(a)pyrene and Coal Tar Tumor DoseResponse Data to a Modified Benchmark Dose Method of Guideline Development AN - 14705112; 10670437 AB - The benchmark dose (BMD) method uses conventional mathematical models to obtain doseresponse curves. In Australia, a modified BMD method has been developed that combines toxicologic doseresponse data and conventional mathematical models to generate doseresponse curves, which avoids the conservatism of other BMD models. In this study, the modified BMD method was used to construct tumor doseresponse curves for benzo(a)pyrene (BaP) using data from a recently published 2-yr feeding study on female B6C3F1 mice. The bioassay also examined the tumor response of the mice to two coal-tar mixtures. Results suggested a BaP soil guideline value of 5 ppm, which would be a significant departure from the current guideline of 1 ppm based on consideration of proportionality of dietary BaP and related cancer risk derived from the EPA conservative linearized multistage model. JF - Environmental Health Perspectives AU - Fitzgerald, DJames AU - Robinson, Neville I AU - Pester, Beverly A Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1341 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - SOIL CONTAMINATION KW - TUMORIGENIC AGENTS KW - COAL TARS KW - DOSE RESPONSE PROFILES KW - MATHEMATIC MODELS, CARCINOGENESIS KW - BENZO-A-PYRENE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705112?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Application+of+Benzo%28a%29pyrene+and+Coal+Tar+Tumor+Dose%26lt%3BND%26gt%3BResponse+Data+to+a+Modified+Benchmark+Dose+Method+of+Guideline+Development&rft.au=Fitzgerald%2C+DJames%3BRobinson%2C+Neville+I%3BPester%2C+Beverly+A&rft.aulast=Fitzgerald&rft.aufirst=DJames&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1341&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - COAL TARS; CANCER RISK; DOSE RESPONSE PROFILES; SOIL CONTAMINATION; MATHEMATIC MODELS, CARCINOGENESIS; BENZO-A-PYRENE; TUMORIGENIC AGENTS ER - TY - JOUR T1 - Paternal Occupational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Birth Outcomes of Offspring: Birth Weight, Preterm Delivery, and Birth Defects AN - 14704828; 10670447 AB - Pregnancy outcomes were examined among wives of male chemical workers who were exposed highly to chemicals contaminated with TCDD and among wives of nonexposed neighborhood referents in New Jersey and Missouri. Dates of employment in TCDD-related processes defined the exposure period, and pregnancies conceived after the father's first date of exposure were considered exposed. A pharmacokinetic model was used to estimate the worker's serum TCDD concentration at the time of conception. The pregnancy outcomes analyzed were birth weight, preterm delivery, and birth defects. No causal relationship was found between low birth weight and high paternal TCDD exposure. Rather, a positive association was observed between paternal dioxin exposure and birth weight. The proportion of preterm births was low in the study population, and it was lower among exposed births. A low incidence of birth defects was reported among the entire study population. JF - Environmental Health Perspectives AU - Lawson, Christina C AU - Schnorr, Teresa M AU - Whelan, Elizabeth A AU - Deddens, James A AU - Dankovic, David A AU - Piacitelli, Laurie A AU - Sweeney, Marie H Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1403 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - REPRODUCTION, HUMAN KW - BIRTH DEFECTS, HUMAN KW - TETRACHLORODIBENZODIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Paternal+Occupational+Exposure+to+2%2C3%2C7%2C8-Tetrachlorodibenzo-p-Dioxin+and+Birth+Outcomes+of+Offspring%3A+Birth+Weight%2C+Preterm+Delivery%2C+and+Birth+Defects&rft.au=Lawson%2C+Christina+C%3BSchnorr%2C+Teresa+M%3BWhelan%2C+Elizabeth+A%3BDeddens%2C+James+A%3BDankovic%2C+David+A%3BPiacitelli%2C+Laurie+A%3BSweeney%2C+Marie+H&rft.aulast=Lawson&rft.aufirst=Christina&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1403&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; REPRODUCTION, HUMAN; BIRTH DEFECTS, HUMAN; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Classification of the Australian continental shelf based on predicted sediment threshold exceedance from tidal currents and swell waves AN - 17305344; 6143397 AB - Estimates of significant wave height and period, together with tidal current speed over a semi-lunar cycle, were used to predict the area on the Australian continental shelf over which unconsolidated sediment was mobilised (threshold exceedance). These sediment-entraining processes were examined independently to quantify their relative importance on the continental shelf. Using observed grain size data, mobilisation from swell waves occurred on ~31% and tidal currents on ~41% of the continental shelf. Swell wave energy is sufficient to mobilise fine sand (0.1 mm diameter) to a water depth of 142 m on the Otway Shelf near the western entrance to Bass Strait. Tidal currents in King Sound (northwest shelf) are capable of mobilising large areas of medium sand (0.35 mm diameter) 100% of the time. Superimposing the distribution of threshold exceedance by wave and tidal currents indicates that there are areas on the shelf where either wave-induced or tidal currents dominate, some areas where waves and tides are of relatively equal importance and still other areas where neither is significant. We define six shelf regions of relative wave and tidal energy: zero (no-mobility); waves-only, wave-dominated, mixed, tide-dominated and tides-only. Our results provide a predictive, process-based understanding of the shelf sedimentary system that has applications to marine engineering projects and to regional studies of pollution dispersal and accumulation where significant shelf sediment mobilisation is a factor. JF - Marine Geology AU - Porter-Smith, R AU - Harris, P T AU - Andersen, O B AU - Coleman, R AU - Greenslade, D AU - Jenkins, C J AD - Geoscience Australia, GPO Box 378, ACT, 2601, Canberra, Australia Y1 - 2004/09/30/ PY - 2004 DA - 2004 Sep 30 SP - 1 EP - 20 VL - 211 IS - 1-2 SN - 0025-3227, 0025-3227 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts KW - Q5 01503:Characteristics, behavior and fate KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17305344?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Geology&rft.atitle=Classification+of+the+Australian+continental+shelf+based+on+predicted+sediment+threshold+exceedance+from+tidal+currents+and+swell+waves&rft.au=Porter-Smith%2C+R%3BHarris%2C+P+T%3BAndersen%2C+O+B%3BColeman%2C+R%3BGreenslade%2C+D%3BJenkins%2C+C+J&rft.aulast=Porter-Smith&rft.aufirst=R&rft.date=2004-09-30&rft.volume=211&rft.issue=1-2&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Marine+Geology&rft.issn=00253227&rft_id=info:doi/10.1016%2Fj.margeo.2004.05.031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-03-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.margeo.2004.05.031 ER - TY - JOUR T1 - CD44 modulates Smad1 activation in the BMP-7 signaling pathway. AN - 66917507; 15452148 AB - Bone morphogenetic protein 7 (BMP-7) regulates cellular metabolism in embryonic and adult tissues. Signal transduction occurs through the activation of intracellular Smad proteins. In this paper, using a yeast two-hybrid screen, Smad1 was found to interact with the cytoplasmic domain of CD44, a receptor for the extracellular matrix macromolecule hyaluronan. Coimmunoprecipitation experiments confirmed the interaction of Smad1 with full-length CD44-interactions that did not occur when CD44 receptors truncated within the cytoplasmic domain were tested. Chondrocytes overexpressing a truncated CD44 on a background of endogenous full-length CD44 no longer exhibited Smad1 nuclear translocation upon BMP-7 stimulation. Further, pretreatment of chondrocytes with Streptomyces hyaluronidase to disrupt extracellular hyaluronan-cell interactions inhibited BMP-7-mediated Smad1 phosphorylation, nuclear translocation of Smad1 or Smad4, and SBE4-luciferase reporter activation. These results support a functional link between the BMP signaling cascade and CD44. Thus, changes in hyaluronan-cell interactions may serve as a means to modulate cellular responsiveness to BMP. JF - The Journal of cell biology AU - Peterson, Richard S AU - Andhare, Roma A AU - Rousche, Kathleen T AU - Knudson, Warren AU - Wang, Weihua AU - Grossfield, Jami B AU - Thomas, Raymond O AU - Hollingsworth, Robert E AU - Knudson, Cheryl B AD - Dept. of Biochemistry, Rush Medical College, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA. Y1 - 2004/09/27/ PY - 2004 DA - 2004 Sep 27 SP - 1081 EP - 1091 VL - 166 IS - 7 SN - 0021-9525, 0021-9525 KW - Antigens, CD44 KW - 0 KW - BMP7 protein, human KW - Bone Morphogenetic Protein 7 KW - Bone Morphogenetic Proteins KW - DNA-Binding Proteins KW - SMAD1 protein, human KW - SMAD4 protein, human KW - Smad Proteins KW - Smad1 Protein KW - Smad4 Protein KW - Trans-Activators KW - Transcription Factors KW - Transforming Growth Factor beta KW - Hyaluronic Acid KW - 9004-61-9 KW - Hyaluronoglucosaminidase KW - EC 3.2.1.35 KW - Index Medicus KW - Animals KW - COS Cells KW - Transcription Factors -- metabolism KW - Active Transport, Cell Nucleus -- drug effects KW - Humans KW - Two-Hybrid System Techniques KW - Hyaluronic Acid -- metabolism KW - Transcription Factors -- genetics KW - Hyaluronoglucosaminidase -- pharmacology KW - Phosphorylation -- drug effects KW - Mutagenesis, Site-Directed KW - Cattle KW - Genes, Reporter -- genetics KW - Transfection KW - Active Transport, Cell Nucleus -- genetics KW - Trans-Activators -- metabolism KW - Extracellular Matrix -- metabolism KW - Antigens, CD44 -- genetics KW - DNA-Binding Proteins -- genetics KW - Bone Morphogenetic Proteins -- genetics KW - Cartilage -- growth & development KW - Antigens, CD44 -- metabolism KW - Trans-Activators -- genetics KW - Cartilage -- metabolism KW - Chondrocytes -- drug effects KW - Cartilage -- cytology KW - Signal Transduction -- drug effects KW - Bone Morphogenetic Proteins -- metabolism KW - Signal Transduction -- genetics KW - Transforming Growth Factor beta -- genetics KW - Transforming Growth Factor beta -- metabolism KW - Chondrocytes -- metabolism KW - DNA-Binding Proteins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66917507?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+cell+biology&rft.atitle=CD44+modulates+Smad1+activation+in+the+BMP-7+signaling+pathway.&rft.au=Peterson%2C+Richard+S%3BAndhare%2C+Roma+A%3BRousche%2C+Kathleen+T%3BKnudson%2C+Warren%3BWang%2C+Weihua%3BGrossfield%2C+Jami+B%3BThomas%2C+Raymond+O%3BHollingsworth%2C+Robert+E%3BKnudson%2C+Cheryl+B&rft.aulast=Peterson&rft.aufirst=Richard&rft.date=2004-09-27&rft.volume=166&rft.issue=7&rft.spage=1081&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+cell+biology&rft.issn=00219525&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-12-02 N1 - Date created - 2004-09-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Nat Rev Cancer. 2004 Jul;4(7):528-39 [15229478] Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12160-4 [1465456] Connect Tissue Res. 1992;28(1-2):143-59 [1628488] Science. 2000 Jan 7;287(5450):92-7 [10615055] Arthritis Rheum. 2000 Jan;43(1):206-14 [10643717] J Histochem Cytochem. 2000 Feb;48(2):239-50 [10639490] Osteoarthritis Cartilage. 2000 Mar;8(2):127-36 [10772243] Arthritis Rheum. 2000 May;43(5):1165-74 [10817571] Genomics. 2000 Oct 1;69(1):63-71 [11013076] J Biol Chem. 2001 May 25;276(21):17871-7 [11278410] J Cell Biol. 2001 May 28;153(5):893-904 [11381077] Biochem J. 2001 Aug 1;357(Pt 3):843-50 [11463356] J Biol Chem. 2001 Oct 19;276(42):39404-10 [11509558] Crit Rev Eukaryot Gene Expr. 2001;11(1-3):23-45 [11693963] Arthritis Rheum. 2001 Nov;44(11):2599-610 [11710716] J Cell Biol. 2001 Nov 26;155(5):755-62 [11714729] Mol Cell. 2001 Dec;8(6):1303-12 [11779505] J Cell Sci. 2001 Dec;114(Pt 24):4359-69 [11792802] Matrix Biol. 2002 Jan;21(1):53-62 [11827792] Cell Mol Life Sci. 2002 Jan;59(1):36-44 [11846031] J Biol Chem. 2002 Mar 22;277(12):10531-8 [11792695] J Biol Chem. 2002 Nov 22;277(47):44754-9 [12223485] Biochim Biophys Acta. 2003 Jan 3;1625(1):30-5 [12527423] Oncogene. 2003 Mar 13;22(10):1511-6 [12629514] J Biol Chem. 2003 May 16;278(20):17688-700 [12637574] J Cell Biol. 2003 Jun 9;161(5):839-43 [12796473] Biochem Biophys Res Commun. 2003 Aug 1;307(3):632-9 [12893270] Birth Defects Res C Embryo Today. 2003 May;69(2):174-96 [12955860] J Cell Sci. 2004 Jan 26;117(Pt 3):373-80 [14702383] J Cell Sci. 1992 Oct;103 ( Pt 2):293-8 [1282514] FASEB J. 1993 Oct;7(13):1233-41 [7691670] J Biol Chem. 1995 Nov 17;270(46):27734-41 [7499241] Biotechniques. 1996 Aug;21(2):255-9 [8862810] Arthritis Rheum. 1996 Nov;39(11):1896-904 [8912513] Nat Biotechnol. 1998 Mar;16(3):247-52 [9528003] J Biol Chem. 1998 Aug 14;273(33):21145-52 [9694870] J Biol Chem. 1998 Sep 4;273(36):22865-8 [9722503] J Biol Chem. 1998 Oct 2;273(40):25628-36 [9748228] Nature. 1999 Apr 8;398(6727):518-22 [10206645] Exp Cell Res. 1999 Nov 1;252(2):292-302 [10527620] Dev Biol. 1987 Nov;124(1):82-90 [2444482] N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - Co-evolution of controversial theories AN - 39843942; 3878856 AU - Steen, T Y1 - 2004/09/21/ PY - 2004 DA - 2004 Sep 21 KW - CPI, Conference Papers Index KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39843942?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Co-evolution+of+controversial+theories&rft.au=Steen%2C+T&rft.aulast=Steen&rft.aufirst=T&rft.date=2004-09-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Pennsylvania State University, College of Earth and Mineral Sciences, 116 Deike Building, University Park, PA 16802, USA; URL: www.outreach.psu.edu N1 - Last updated - 2010-05-03 ER - TY - GEN T1 - Nomination of the Honorable Porter J. Goss to Be Director of Central Intelligence AN - 1679147032; CO02125 AB - Transcribes Senate Select Committee on Intelligence hearing about nomination of Porter Goss for director of central intelligence. AU - United States. Congress. Senate. Select Committee on Intelligence AD - United States. Congress. Senate. Select Committee on Intelligence PY - 2004 SP - 210 KW - Biography KW - Confirmation hearings KW - Government budgeting KW - Human intelligence KW - Intelligence cooperation KW - Iraq War (2003-) KW - Military intelligence KW - New York Times KW - News media KW - September 11 Attacks (2001) KW - Washington Post KW - Washington Times KW - Weapons of mass destruction KW - Mikulski, Barbara A. KW - DeWine, Michael KW - Levin, Carl KW - Thomas, Cynthia A. KW - Hussein, Saddam KW - Kerry, John F. KW - Bush, George W. KW - Warner, John William KW - Durbin, Richard J. KW - Glynn, Marilyn L. KW - Bayh, Evan KW - Hatch, Orrin G. KW - Goss, Porter J. KW - Hagel, Charles T. KW - Feinstein, Dianne KW - Nelson, William E. KW - Rockefeller, John D. IV ("Jay") KW - Graham, Robert KW - Chambliss, Saxby KW - Rizzo, John A. KW - Wyden, Ron KW - Snowe, Olympia J. KW - Roberts, Charles Patrick KW - Mikulski, Barbara A. KW - DeWine, Michael KW - Levin, Carl KW - Thomas, Cynthia A. KW - Hussein, Saddam KW - Kerry, John F. KW - Bush, George W. KW - Warner, John William KW - Durbin, Richard J. KW - Glynn, Marilyn L. KW - Bayh, Evan KW - Hatch, Orrin G. KW - Goss, Porter J. KW - Hagel, Charles T. KW - Feinstein, Dianne KW - Nelson, William E. KW - Rockefeller, John D. IV ("Jay") KW - Graham, Robert KW - Chambliss, Saxby KW - Rizzo, John A. KW - Wyden, Ron KW - Snowe, Olympia J. KW - Roberts, Charles Patrick UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679147032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_co&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Nomination+of+the+Honorable+Porter+J.+Goss+to+Be+Director+of+Central+Intelligence&rft.au=United+States.+Congress.+Senate.+Select+Committee+on+Intelligence&rft.aulast=United+States.+Congress.+Senate.+Select+Committee+on+Intelligence&rft.aufirst=&rft.date=2004-09-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - Al-Qaeda; Democratic Party; National Commission on Terrorist Attacks upon the United States; TriDimension Strategies; United States. Central Intelligence Agency; United States. Congress. House. Permanent Select Committee on Intelligence; United States. Department of Defense. Secretary; United States. Director of Central Intelligence; United States. Federal Bureau of Investigation. Director N1 - Analyte descriptor - NSA document type: Hearing N1 - People - Bayh, Evan; Bush, George W.; Chambliss, Saxby; DeWine, Michael; Durbin, Richard J.; Feinstein, Dianne; Glynn, Marilyn L.; Goss, Porter J.; Graham, Robert; Hagel, Charles T.; Hatch, Orrin G.; Hussein, Saddam; Kerry, John F.; Levin, Carl; Mikulski, Barbara A.; Nelson, William E.; Rizzo, John A.; Roberts, Charles Patrick; Rockefeller, John D. IV ("Jay"); Snowe, Olympia J.; Thomas, Cynthia A.; Warner, John William; Wyden, Ron N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - A bidirectional gene trap construct suitable for T-DNA and Ds-mediated insertional mutagenesis in rice (Oryza sativa L.). AN - 734178568; 17168884 AB - A construct suitable for genome-wide transfer-DNA (T-DNA) and subsequent transposon-based (Ds) gene trapping has been developed for use in rice (Oryza sativa). This T-DNA/Ds construct contains: Ds terminal sequences immediately inside T-DNA borders for subsequent Ds mobilization; promoterless green fluorescent protein (sgfpS65T) and beta-glucuronidase (uidA) reporter genes, each fused to an intron (from Arabidopsis GPA1 gene) to enable bidirectional gene trapping by T-DNA or Ds; an ampicillin resistance gene (bla) and a bacterial origin of replication (ori) to serve as the plasmid rescue system; an intron-containing hygromycin phosphotransferase gene (hph) as a selectable marker or Ds tracer; and an intron-containing barnase gene in the binary vector backbone (VB) to select against transformants carrying unwanted VB sequences. More than a threefold increase over previously reported reporter gene-based gene trapping efficiencies was observed in primary T-DNA/Ds transformant rice lines, returning an overall reporter gene expression frequency of 23%. Of the plant organs tested, 3.3-7.4% expressed either reporter at varying degrees of organ or tissue specificity. Approximately 70% of the right border (RB) flanking sequence tags (FSTs) retained 1-6 bp of the RB repeat and 30% of the left border (LB) FSTs retained 5-23 bp of the LB repeat. The remaining FSTs carried deletions of 2-84 bp inside the RB or 1-97 bp inside the LB. Transposition of Ds from the original T-DNA was evident in T-DNA/Ds callus lines super-transformed with a transposase gene (Ac) construct, as indicated by gene trap reporter activity and rescue of new FSTs in the resulting double transformant lines. JF - Plant biotechnology journal AU - Eamens, Andrew L AU - Blanchard, Chris L AU - Dennis, Elizabeth S AU - Upadhyaya, Narayana M AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia. Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 367 EP - 380 VL - 2 IS - 5 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734178568?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+biotechnology+journal&rft.atitle=A+bidirectional+gene+trap+construct+suitable+for+T-DNA+and+Ds-mediated+insertional+mutagenesis+in+rice+%28Oryza+sativa+L.%29.&rft.au=Eamens%2C+Andrew+L%3BBlanchard%2C+Chris+L%3BDennis%2C+Elizabeth+S%3BUpadhyaya%2C+Narayana+M&rft.aulast=Eamens&rft.aufirst=Andrew&rft.date=2004-09-01&rft.volume=2&rft.issue=5&rft.spage=367&rft.isbn=&rft.btitle=&rft.title=Plant+biotechnology+journal&rft.issn=1467-7652&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-02 N1 - Date created - 2006-12-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The Law: Recess Appointments to Article III Courts AN - 60709040; 200502754 AB - Under the Constitution, the president & the Senate share the power to appoint officers of the US, including federal judges. The Constitution also empowers the president to make temporary appointments without the Senate's approval during Senate recesses. Presidents have made over 300 recess appointments to Article III courts, but the practice has become rare in the last 40 years. Although courts have found tension between Article II & Article III inherent in judicial recess appointments, the practice has been held to be constitutional. Intrasession recess appointments, particularly during recesses of less than 30 days, have sometimes proven controversial. 1 Table, 38 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Hogue, Henry B AD - Congressional Research Service, Library Congress Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 656 EP - 673 VL - 34 IS - 3 SN - 0360-4918, 0360-4918 KW - Appointment KW - Presidents KW - United States of America KW - Legislative Bodies KW - Constitutions KW - Judges KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60709040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=The+Law%3A+Recess+Appointments+to+Article+III+Courts&rft.au=Hogue%2C+Henry+B&rft.aulast=Hogue&rft.aufirst=Henry&rft.date=2004-09-01&rft.volume=34&rft.issue=3&rft.spage=656&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 38 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States of America; Presidents; Legislative Bodies; Judges; Appointment; Constitutions ER - TY - JOUR T1 - IDA Grants and HIPC Debt Cancellation: Their Effectiveness and Impact on IDA Resources AN - 59692635; 200602771 AB - IDA is in trouble. The World Bank's long-term plans presume that IDA will need all the loan repayments currently scheduled just to keep its program from shrinking in future decades. Yet the IDA grant & HIPC debt reduction programs are cutting the flow of repayments, foreshadowing major future cuts in IDA aid. Unless the donor countries agree on a plan to offset those costs, poor countries will suffer. Meanwhile, the efficiency & effectiveness of the grant & debt cancellation programs have been seriously questioned. These programs are evaluated & changes in the Bank's future plans for IDA are proposed. 3 Tables, 4 Figures, 82 References. [Copyright 2004 Elsevier Ltd.] JF - World Development AU - Sanford, Jonathan E AD - Congressional Research Service, Library Congress, Washington, DC Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 1579 EP - 1607 VL - 32 IS - 9 SN - 0305-750X, 0305-750X KW - Foreign Aid KW - Public Debt KW - Loans KW - Economic Development KW - International Economic Organizations KW - article KW - 9141: political economy; political economy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59692635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=World+Development&rft.atitle=IDA+Grants+and+HIPC+Debt+Cancellation%3A+Their+Effectiveness+and+Impact+on+IDA+Resources&rft.au=Sanford%2C+Jonathan+E&rft.aulast=Sanford&rft.aufirst=Jonathan&rft.date=2004-09-01&rft.volume=32&rft.issue=9&rft.spage=1579&rft.isbn=&rft.btitle=&rft.title=World+Development&rft.issn=0305750X&rft_id=info:doi/10.1016%2Fj.worlddev.2004.04.001 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 82 N1 - Last updated - 2016-09-28 N1 - CODEN - WODEDW N1 - SubjectsTermNotLitGenreText - Economic Development; International Economic Organizations; Public Debt; Loans; Foreign Aid DO - http://dx.doi.org/10.1016/j.worlddev.2004.04.001 ER - TY - JOUR T1 - Follow-Up Study of Adolescents Exposed to Di(2-Ethylhexyl) Phthalate (DEHP) as Neonates on Extracorporeal Membrane Oxygenation (ECMO) Support AN - 21194225; 11492289 AB - Di(2-ethylhexyl) phthalate (DEHP) is used to make polyvinyl chloride (PVC) plastic tubing soft and flexible. Animal data show that adverse effects of DEHP exposure may include reduced fertility, reduced sperm production in males, and ovarian dysfunction in females. Known treatments that involve high DEHP exposures are blood exchange transfusions, extracorporeal membrane oxygenation (ECMO), and cardiovascular surgery. Although potential exposure to DEHP in ECMO patients is significant, the exposure has not been associated with short-term toxicity. To evaluate long-term toxicity, we undertook a study of neonatal ECMO survivors to assess their onset of puberty and sexual maturity. We evaluated 13 male and 6 female subjects at 14-16 years of age who had undergone ECMO as neonates. All subjects had a complete physical examination including measurements for height, weight, head circumference, and pubertal assessment by Tanner staging. The testicular volume and the phallic length were measured in male participants. Laboratory tests included thyroid, liver, and renal function as well as measurements of luteinizing hormone, follicle-stimulating hormone, testosterone for males, and estradiol for females. Except for one patient with Marfan syndrome, the rest had normal growth percentile for age and sex. All had normal values for thyroid, liver, and renal functions. Sexual hormones were appropriate for the stage of pubertal maturity. Our results indicate that adolescents exposed to significant quantities of DEHP as neonates showed no significant adverse effects on their physical growth and pubertal maturity. Thyroid, liver, renal, and male and female gonadal functions tested were within normal range for age and sex distribution. Key Words: DEHP, ECMO, toxicity. JF - Environmental Health Perspectives AU - Rais-Bahrami, Khodayar AU - Nunez, Susan AU - Revenis, Mary E AU - Luban, Naomi L C AU - Short, Billie L Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1339 EP - 1340 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts; Environment Abstracts; Environmental Engineering Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21194225?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Follow-Up+Study+of+Adolescents+Exposed+to+Di%282-Ethylhexyl%29+Phthalate+%28DEHP%29+as+Neonates+on+Extracorporeal+Membrane+Oxygenation+%28ECMO%29+Support&rft.au=Rais-Bahrami%2C+Khodayar%3BNunez%2C+Susan%3BRevenis%2C+Mary+E%3BLuban%2C+Naomi+L+C%3BShort%2C+Billie+L&rft.aulast=Rais-Bahrami&rft.aufirst=Khodayar&rft.date=2004-09-01&rft.volume=111&rft.issue=8&rft.spage=1131&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Developmental Dental Aberrations After the Dioxin Accident in Seveso AN - 21188687; 11492280 AB - Children's developing teeth may be sensitive to environmental dioxins, and in animal studies developing teeth are one of the most sensitive targets of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Twenty-five years after the dioxin accident in Seveso, Italy, 48 subjects from the contaminated areas (zones A and B) and in patches lightly contaminated (zone R) were recruited for the examination of dental and oral aberrations. Subjects were randomly invited from those exposed in their childhood and for whom frozen serum samples were available. The subjects were frequency matched with 65 subjects from the surrounding non-ABR zone for age, sex, and education. Concentrations of TCDD in previously analyzed plasma samples (zone ABR subjects only) ranged from 23 to 26,000 ng/kg in serum lipid. Ninety-three percent (25 of 27) of the subjects who had developmental enamel defects had been 5 years of age at the time of the accident. The prevalence of defects in this age group was 42% (15 of 36) in zone ABR subjects and 26% (10 of 39) in zone non-ABR subjects, correlating with serum TCDD levels (p = 0.016). Hypodontia was seen in 12.5% (6 of 48) and 4.6% (3 of 65) of the zone ABR and non-ABR subjects, respectively, also correlating with serum TCDD level (p = 0.05). In conclusion, developmental dental aberrations were associated with childhood exposure to TCDD. In contrast, dental caries and periodontal disease, both infectious in nature, and oral pigmentation and salivary flow rate were not related to the exposure. The results support our hypothesis that dioxins can interfere with human organogenesis. JF - Environmental Health Perspectives AU - Alaluusua, Satu AU - Calderara, Pier AU - Gerthoux, Pier Mario AU - Lukinmaa, Pirjo-Liisa Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1313 EP - 1318 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21188687?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developmental+Dental+Aberrations+After+the+Dioxin+Accident+in+Seveso&rft.au=Alaluusua%2C+Satu%3BCalderara%2C+Pier%3BGerthoux%2C+Pier+Mario%3BLukinmaa%2C+Pirjo-Liisa&rft.aulast=Alaluusua&rft.aufirst=Satu&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1313&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Postweaning Exposure to Aflatoxin Results in Impaired Child Growth: A Longitudinal Study in Benin, West Africa AN - 21186869; 11492279 AB - Aflatoxins are dietary contaminants that are hepatocarcinogenic and immunotoxic and cause growth retardation in animals, but there is little evidence concerning the latter two parameters in exposed human populations. Aflatoxin exposure of West African children is known to be high, so we conducted a longitudinal study over an 8-month period in Benin to assess the effects of exposure on growth. Two hundred children 16-37 months of age were recruited from four villages, two with high and two with low aflatoxin exposure (50 children per village). Serum aflatoxin-albumin (AF-alb) adducts, anthropometric parameters, information on food consumption, and various demographic data were measured at recruitment (February) and at two subsequent time points (June and October). Plasma levels of vitamin A and zinc were also measured. AF-alb adducts increased markedly between February and October in three of the four villages, with the largest increases in the villages with higher exposures. Children who were fully weaned at recruitment had higher AF-alb than did those still partially breast-fed (p 0.0001); the major weaning food was a maize-based porridge. There was no association between AF-alb and micronutrient levels, suggesting that aflatoxin exposure was not accompanied by a general nutritional deficiency. There was, however, a strong negative correlation (p 0.0001) between AF-alb and height increase over the 8-month follow-up after adjustment for age, sex, height at recruitment, socioeconomic status, village, and weaning status; the highest quartile of AF-alb was associated with a mean 1.7 cm reduction in growth over 8 months compared with the lowest quartile. This study emphasizes the association between aflatoxin and stunting, although the underlying mechanisms remain unclear. Aflatoxin exposure during the weaning period may be critical in terms of adverse health effects in West African children, and intervention measures to reduce exposure merit investigation. JF - Environmental Health Perspectives AU - Gong, Yunyun AU - Hounsa, Assomption AU - Egal, Sharif AU - Turner, Paul C Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1334 EP - 1338 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24320:Food Additives & Contaminants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21186869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Postweaning+Exposure+to+Aflatoxin+Results+in+Impaired+Child+Growth%3A+A+Longitudinal+Study+in+Benin%2C+West+Africa&rft.au=Gong%2C+Yunyun%3BHounsa%2C+Assomption%3BEgal%2C+Sharif%3BTurner%2C+Paul+C&rft.aulast=Gong&rft.aufirst=Yunyun&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1334&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Subcutaneous Injection of Mercury: "Warding Off Evil" AN - 21185793; 11492286 AB - Deliberate injection of mercury, especially subcutaneous injection, is rare but is seen in psychiatric patients, individuals who attempt suicide, those who are accidentally injected, and boxers who wish to build muscle bulk. Metallic mercury plays a major role in ethnic folk medicine. Neurologic and renal complications can result from high systemic levels of mercury, and subcutaneous injection usually results in sterile abscesses. Urgent surgical evacuation and close monitoring for neurologic and renal functions as well as chelation (if toxicity is indicated) are key aspects of treatment. Education of the adverse effects and dangers of mercury is important, especially in pregnant women and children. As increased immigration changes demographic patterns, proper disposal of mercury and preventing its sale and use should become urgent societal priorities. Psychiatric consultation should be obtained whenever appropriate. JF - Environmental Health Perspectives AU - Prasad, Venkat L Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1326 EP - 1328 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21185793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Subcutaneous+Injection+of+Mercury%3A+%22Warding+Off+Evil%22&rft.au=Prasad%2C+Venkat+L&rft.aulast=Prasad&rft.aufirst=Venkat&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1326&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Water Arsenic Exposure and Children's Intellectual Function in Araihazar, Bangladesh AN - 21185765; 11492283 AB - Exposure to arsenic has long been known to have neurologic consequences in adults, but to date there are no well-controlled studies in children. We report results of a cross-sectional investigation of intellectual function in 201 children 10 years of age whose parents participate in our ongoing prospective cohort study examining health effects of As exposure in 12,000 residents of Araihazar, Bangladesh. Water As and manganese concentrations of tube wells at each child's home were obtained by surveying all wells in the study region. Children and mothers came to our field clinic, where children received a medical examination in which weight, height, and head circumference were measured. Children's intellectual function on tests drawn from the Wechsler Intelligence Scale for Children, version III, was assessed by summing weighted items across domains to create Verbal, Performance, and Full-Scale raw scores. Children provided urine specimens for measuring urinary As and creatinine and were asked to provide blood samples for measuring blood lead and hemoglobin concentrations. Exposure to As from drinking water was associated with reduced intellectual function after adjustment for sociodemographic covariates and water Mn. Water As was associated with reduced intellectual function, in a dose-response manner, such that children with water As levels 50 microg/L achieved significantly lower Performance and Full-Scale scores than did children with water As levels 5.5 microg/L. The association was generally stronger for well-water As than for urinary As. JF - Environmental Health Perspectives AU - Wasserman, Gail A AU - Liu, Xinhua AU - Parvez, Faruque AU - Ahsan, Habibul Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1329 EP - 1333 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21185765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Water+Arsenic+Exposure+and+Children%27s+Intellectual+Function+in+Araihazar%2C+Bangladesh&rft.au=Wasserman%2C+Gail+A%3BLiu%2C+Xinhua%3BParvez%2C+Faruque%3BAhsan%2C+Habibul&rft.aulast=Wasserman&rft.aufirst=Gail&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1329&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - A Bayesian Hierarchical Approach for Relating PM sigma ub 2.5Exposure to Cardiovascular Mortality in North Carolina AN - 21165717; 11492285 AB - Considerable attention has been given to the relationship between levels of fine particulate matter (particulate matter or = 2.5 microm in aerodynamic diameter; PM(2.5) in the atmosphere and health effects in human populations. Since the U.S. Environmental Protection Agency began widespread monitoring of PM(2.5) levels in 1999, the epidemiologic community has performed numerous observational studies modeling mortality and morbidity responses to PM(2.5) levels using Poisson generalized additive models (GAMs). Although these models are useful for relating ambient PM(2.5) levels to mortality, they cannot directly measure the strength of the effect of exposure to PM(2.5) on mortality. In order to assess this effect, we propose a three-stage Bayesian hierarchical model as an alternative to the classical Poisson GAM. Fitting our model to data collected in seven North Carolina counties from 1999 through 2001, we found that an increase in PM(2.5) exposure is linked to increased risk of cardiovascular mortality in the same day and next 2 days. Specifically, a 10- microg/m3 increase in average PM(2.5) exposure is associated with a 2.5% increase in the relative risk of current-day cardiovascular mortality, a 4.0% increase in the relative risk of cardiovascular mortality the next day, and an 11.4% increase in the relative risk of cardiovascular mortality 2 days later. Because of the small sample size of our study, only the third effect was found to have 95% posterior probability of being 0. In addition, we compared the results obtained from our model to those obtained by applying frequentist (or classical, repeated sampling-based) and Bayesian versions of the classical Poisson GAM to our study population. JF - Environmental Health Perspectives AU - Holloman, Christopher H AU - Bortnick, Steven M AU - Morara, Michele AU - Strauss, Warren J AU - Calder, Catherine A Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1282 EP - 1288 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Risk Abstracts; Environment Abstracts; Environmental Engineering Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21165717?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Bayesian+Hierarchical+Approach+for+Relating+PM+sigma+ub+2.5Exposure+to+Cardiovascular+Mortality+in+North+Carolina&rft.au=Holloman%2C+Christopher+H%3BBortnick%2C+Steven+M%3BMorara%2C+Michele%3BStrauss%2C+Warren+J%3BCalder%2C+Catherine+A&rft.aulast=Holloman&rft.aufirst=Christopher&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1282&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Dioxin Revisited: Developments Since the 1997 IARC Classification of Dioxin as a Human Carcinogen AN - 21161451; 11492282 AB - In 1997 the International Agency for Research on Cancer (IARC) classified 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; the most potent dioxin congener) as a group 1 carcinogen based on limited evidence in humans, sufficient evidence in experimental animals, and extensive mechanistic information indicating that TCDD acts through a mechanism involving the aryl hydrocarbon receptor (AhR), which is present in both humans and animals. The judgment of limited evidence in humans was based primarily on an elevation of all cancers combined in four industrial cohorts. The group 1 classification has been somewhat controversial and has been challenged in the literature in recent years. In this article we review the epidemiologic and mechanistic evidence that has emerged since 1997. New epidemiologic evidence consists primarily of positive exposure-response analyses in several of the industrial cohorts, as well as evidence of excesses of several specific cancers in the Seveso accident cohort. There are also new data regarding how the AhR functions in mediating the carcinogenic response to TCDD. The new evidence generally supports the 1997 IARC classification. JF - Environmental Health Perspectives AU - Steenland, Kyle AU - Bertazzi, Pier AU - Baccarelli, Andrea AU - Kogevinas, Manolis Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1265 EP - 1268 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21161451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Dioxin+Revisited%3A+Developments+Since+the+1997+IARC+Classification+of+Dioxin+as+a+Human+Carcinogen&rft.au=Steenland%2C+Kyle%3BBertazzi%2C+Pier%3BBaccarelli%2C+Andrea%3BKogevinas%2C+Manolis&rft.aulast=Metcalfe&rft.aufirst=D&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5810 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Serum Dioxin Concentrations and Age at Menarche AN - 21140186; 11492288 AB - 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a widespread environmental contaminant, is associated with delays in pubertal development in animal studies. On 10 July 1976, as a result of a chemical explosion, residents of Seveso, Italy, experienced the highest levels of TCDD exposure experienced by a human population. Twenty years later, we initiated the Seveso Women's Health Study (SWHS), a retrospective cohort study of female residents of the most contaminated areas, to determine whether the women were at higher risk for reproductive disease. We examined the association of TCDD serum levels, based on measurements in serum collected soon after the explosion, with reported age at menarche among the 282 SWHS women who were premenarcheal at the time of the explosion. We found no change in risk of onset of menarche with a 10-fold increase in TCDD (e.g., 10-100 ppt; hazard ratio = 0.95; 95% confidence interval, 0.83-1.09; p-value for trend = 0.46). When TCDD levels were categorized, there was also no evidence of a dose-response trend (p = 0.65). In summary, we found that individual serum TCDD measurements are not significantly related to age at menarche among women in the SWHS cohort. The women in this study experienced substantial TCDD exposure during the postnatal but prepubertal developmental period. Given that animal evidence suggests in utero exposure has the most significant effect on onset of puberty, continued follow-up of the offspring of the SWHS cohort is important. JF - Environmental Health Perspectives AU - Warner, Marcella AU - Samuels, Steven AU - Mocarelli, Paolo AU - Gerthoux, Pier Mario Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1289 EP - 1292 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - A 01450:Environmental Pollution & Waste Treatment KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21140186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Serum+Dioxin+Concentrations+and+Age+at+Menarche&rft.au=Warner%2C+Marcella%3BSamuels%2C+Steven%3BMocarelli%2C+Paolo%3BGerthoux%2C+Pier+Mario&rft.aulast=Warner&rft.aufirst=Marcella&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1289&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Habitat structure mediates the non-lethal effects of predation on enclosed populations of house mice AN - 18061152; 6011171 AB - Prey behavioural changes in response to predation risk can result in significant effects on prey body growth rates and reduced reproductive output, with resultant impacts on prey population dynamics. This paper examines the influence of habitat structure on these non-lethal impacts of predation using a model, field-based experimental system, with house mice as prey. Three treatments were employed in eight 50 x 50 m pens that contained mice, but allowed access to a suite of free-living vertebrate predators, which included feral foxes, feral cats and native raptors: a treatment where the natural grassland vegetation in the pens was maintained at a height < 10 cm; a treatment where small, felled cypress pine trees covered with wire netting were added to low grassland vegetation to create refuge areas covering 10-15% of the area in a pen; and a treatment where predators were excluded from a 25 x 25 m section of some pens with an underlying grassland structure. A 5 x 5 grid of felled trees was added to grassland and predator-exclusion pens to allow assessment of mouse behaviour. Mice in grassland pens avoided open areas, had lower body growth rates, and began breeding later in spring than mice in both predator-exclusion areas, where they foraged more readily in the open, and in refuge pens, where mice avoided open areas but had safe access to supplementary food located within the refuge. These results occurred despite mouse population densities being much lower in grassland pens, and presumably competition for food being much less, compared with under the other treatments. The results indicate predators can have significant non-lethal impacts on prey, and these effects can be mediated by habitat structure. JF - Journal of Animal Ecology AU - Arthur, AD AU - Pech, R P AU - Dickman, C R AD - Pest Animal Control CRC, CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT, 2601, Australia, tony.arthur@csiro.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 867 EP - 877 PB - Blackwell Science Ltd VL - 73 IS - 5 SN - 0021-8790, 0021-8790 KW - Ecology Abstracts KW - Predator-prey interactions KW - Anti-predator behavior KW - Predation KW - Habitat preferences KW - Cover KW - Mus musculus KW - D 04672:Mammals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18061152?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Animal+Ecology&rft.atitle=Habitat+structure+mediates+the+non-lethal+effects+of+predation+on+enclosed+populations+of+house+mice&rft.au=Arthur%2C+AD%3BPech%2C+R+P%3BDickman%2C+C+R&rft.aulast=Arthur&rft.aufirst=AD&rft.date=2004-09-01&rft.volume=73&rft.issue=5&rft.spage=867&rft.isbn=&rft.btitle=&rft.title=Journal+of+Animal+Ecology&rft.issn=00218790&rft_id=info:doi/10.1111%2Fj.0021-8790.2004.00864.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Mus musculus; Predation; Habitat preferences; Cover; Predator-prey interactions; Anti-predator behavior DO - http://dx.doi.org/10.1111/j.0021-8790.2004.00864.x ER - TY - JOUR T1 - Biases associated with the use of underwater visual census techniques to quantify the density and size-structure of fish populations AN - 18057035; 5977778 AB - Estimates of reef fish densities made by divers visually censusing 5 m wide strip transects were compared with capture-resight estimates calculated independently using data on the resighting frequencies of fish marked with colour-coded tags. The difference in density estimates between methods varied between species but with patterns consistent at the three eastern Tasmanian sites studied. Densities of the two most abundant species, the wrasses Notolabrus tetricus and Notolabrus fucicola, showed good agreement between methods. By contrast, populations of the two monacanthids Meuschenia australis and Meuschenia freycineti were underestimated by an order of magnitude in strip transects relative to capture-resight, while populations of the open-water latrid Latridopsis forsteri were overestimated. For all common fish species observed in strip transects, variation in density estimates between divers was extremely low compared to variation between sites and between months. Variation in density estimates between different days within a week and between 50 m blocks located 50 m apart was also negligible; however, residual error associated with variation by a single diver within a block and day was high. Biases associated with changing detectability of fishes in open versus densely vegetated habitats were assessed by algal removal experiments, and were found to be negligible or non-significantly low for five of the six species examined. The exceptional species; N. tetricus; exhibited a 70% rise in fish sighted by diver following algal clearance despite trapping data indicating no increase in fish numbers. Diver estimates of fish length were on average 7% greater than measured lengths. Divers possessed a clear tendency to make increasingly inaccurate size estimates as fish length deviated in either direction from 300 mm. Lengths of 175-mm animals were underestimated by 20% and 400-mm fishes were overestimated by 10%. These changes in diver bias with fish size were largely independent of fish species, site and diver. The precision of size estimates, as indicated by the standard deviation of bias, also varied with fish size, with values varying from 13% at 200 mm fish length to 8% at 400 mm length. The decline in precision at small body size largely reflected size intervals used by divers to bin data. Divers appear capable of making more precise size estimates than the 25-mm interval used at small fish sizes. JF - Journal of Experimental Marine Biology and Ecology AU - Edgar, G J AU - Barrett, N S AU - Morton, A J AD - Zoology Department, Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, GPO Box 252-05, Hobart Tasmania, 7001, Australia, g.edgar@utas.edu.au Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 269 EP - 290 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 308 IS - 2 SN - 0022-0981, 0022-0981 KW - Biases KW - Capture-resight estimates KW - Comparative studies KW - Silver trumpeter KW - Wrasse KW - Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Fish census KW - Notolabrus tetricus KW - Observer bias KW - Precision KW - Rocky reef KW - Strip transect KW - Viewing underwater KW - Reefs KW - Meuschenia freycineti KW - Population density KW - PSE, Australia, Tasmania, East Coast KW - Divers KW - Latridopsis forsteri KW - Body size KW - Habitat utilization KW - Meuschenia australis KW - Tagging KW - Notolabrus fucicola KW - Marine KW - Monocanthidae KW - Errors KW - Trapping KW - Methodology KW - Dominant species KW - Analytical techniques KW - Census KW - Population structure KW - Latridopsis KW - Size distribution KW - Reef fish KW - O 1070:Ecology/Community Studies KW - Q1 08382:Ecological techniques and apparatus KW - D 04001:Methodology - general UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18057035?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.atitle=Biases+associated+with+the+use+of+underwater+visual+census+techniques+to+quantify+the+density+and+size-structure+of+fish+populations&rft.au=Edgar%2C+G+J%3BBarrett%2C+N+S%3BMorton%2C+A+J&rft.aulast=Edgar&rft.aufirst=G&rft.date=2004-09-01&rft.volume=308&rft.issue=2&rft.spage=269&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.issn=00220981&rft_id=info:doi/10.1016%2Fj.jembe.2004.03.004 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Viewing underwater; Dominant species; Analytical techniques; Population density; Population structure; Census; Tagging; Errors; Size distribution; Divers; Reef fish; Methodology; Reefs; Body size; Habitat utilization; Trapping; Monocanthidae; Latridopsis forsteri; Meuschenia freycineti; Notolabrus tetricus; Meuschenia australis; Latridopsis; Notolabrus fucicola; PSE, Australia, Tasmania, East Coast; Marine DO - http://dx.doi.org/10.1016/j.jembe.2004.03.004 ER - TY - JOUR T1 - Benchmarking and regulation - Advantages and conflicts AN - 18057014; 6063856 AB - The two principal applications of benchmarking as it relates to water businesses are: 1. Those benchmarks undertaken by the water businesses (e.g. for internal and business improvements). 2. Those benchmarks undertaken on the water businesses. (e.g. for external regulatory, stakeholder, owner and consumer purposes.) My two contentions for this paper, based on experience, are: a) internal and external benchmark studies are incompatible; and b) benchmarking, for setting utility prices, should be an input process and not an output process. JF - Water (Australia) AU - Seipolt, A AD - Parsons Brinckerhoff International (Australia), Level 7, 457 St Kilda Rd, GPO Box 4714 TT, Melbourne, Victoria, Australia, seipolta@pbworld.com Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 42 EP - 43 VL - 31 IS - 6 SN - 0310-0367, 0310-0367 KW - Aqualine Abstracts KW - Pricing KW - Water Management KW - Decision Making KW - Utilities KW - AQ 00001:Water Resources and Supplies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18057014?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+%28Australia%29&rft.atitle=Benchmarking+and+regulation+-+Advantages+and+conflicts&rft.au=Seipolt%2C+A&rft.aulast=Seipolt&rft.aufirst=A&rft.date=2004-09-01&rft.volume=31&rft.issue=6&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Water+%28Australia%29&rft.issn=03100367&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Utilities; Pricing; Water Management; Decision Making ER - TY - JOUR T1 - Habitat structural complexity mediates the foraging success of multiple predator species AN - 18056604; 6018041 AB - We investigated the role of freshwater macrophytes as refuge by testing the hypothesis that predators capture fewer prey in more dense and structurally complex habitats. We also tested the hypothesis that habitat structure not only affects the prey-capture success of a single predator in isolation, but also the effectiveness of two predators combined, particularly if it mediates interactions between the predators. We conducted a fully crossed four-factorial laboratory experiment using artificial plants to determine the separate quantitative (density) and qualitative (shape) components of macrophyte structure on the prey-capture success of a predatory damselfly, Ischnura heterosticta tasmanica, and the southern pygmy perch, Nannoperca australis. Contrary to our expectations, macrophyte density had no effect on the prey-capture success of either predator, but both predators were significantly less effective in the structurally complex Myriophyllum analogue than in the structurally simpler Triglochin and Eleocharis analogues. Furthermore, the greater structural complexity of Myriophyllum amplified the impact of the negative interaction between the predators on prey numbers; the habitat use by damselfly larvae in response to the presence of southern pygmy perch meant they captured less prey in Myriophyllum. These results demonstrate habitat structure can influence multiple predator effects, and support the mechanism of increased prey refuge in more structurally complex macrophytes. JF - Oecologia AU - Warfe, D M AU - Barmuta, LA AD - School of Zoology and Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, GPO Box 252-05, 7001, Hobart, Tasmania, Australia, Danielle.Warfe@dpiwe.tas.gov.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 171 EP - 178 PB - Springer-Verlag VL - 141 IS - 1 SN - 0029-8549, 0029-8549 KW - Damselflies KW - Entomology Abstracts; Animal Behavior Abstracts; Ecology Abstracts KW - Myriophyllum KW - Ischnuridae KW - Triglochin KW - Habitat utilization KW - Nannoperca australis KW - Zygoptera KW - Odonata KW - Ischnura heterosticta tasmanica KW - Predator-prey interactions KW - Macrophytes KW - Freshwater ecosystems KW - Eleocharis KW - D 04659:Insects KW - Y 25503:Insects KW - Z 05199:Feeding UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18056604?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Oecologia&rft.atitle=Habitat+structural+complexity+mediates+the+foraging+success+of+multiple+predator+species&rft.au=Warfe%2C+D+M%3BBarmuta%2C+LA&rft.aulast=Warfe&rft.aufirst=D&rft.date=2004-09-01&rft.volume=141&rft.issue=1&rft.spage=171&rft.isbn=&rft.btitle=&rft.title=Oecologia&rft.issn=00298549&rft_id=info:doi/10.1007%2Fs00442-004-1644-x L2 - http://link.springer.de/link/service/journals/00442/bibs/4141001/41410171.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Ischnura heterosticta tasmanica; Odonata; Zygoptera; Ischnuridae; Myriophyllum; Nannoperca australis; Triglochin; Eleocharis; Predator-prey interactions; Macrophytes; Habitat utilization; Freshwater ecosystems DO - http://dx.doi.org/10.1007/s00442-004-1644-x ER - TY - JOUR T1 - Identification, characterisation and specificity of a cell wall lytic enzyme from Lactobacillus fermentum BR11 AN - 17757410; 6054117 AB - Screening of a genomic library with an antiserum raised against whole Lactobacillus fermentum BR11 cells identified a clone expressing an immunoreactive 37-kDa protein. Analysis of the 3010-bp DNA insert contained within the clone revealed four open reading frames (ORFs). One ORF encodes LysA, a 303 amino acid protein which has up to 35% identity with putative endolysins from prophages Lj928 and Lj965 from Lactobacillus johnsonii and Lp1 and Lp2 from Lactobacillus plantarum as well as with the endolysin of Lactobacillus gasseri bacteriophage Theta adh. The immunoreactive protein was shown to be encoded by a truncated ORF downstream of lysA which has similarity to glutamyl-tRNA synthetases. The N-terminus of LysA has sequence similarity with N-acetylmuramidase catalytic domains while the C-terminus has sequence similarity with putative cell envelope binding bacterial SH3b domains. C-terminal bacterial SH3b domains were identified in the majority of Lactobacillus bacteriophage endolysins. LysA was expressed in Escherichia coli and unusually was found to have a broad bacteriolytic activity range with activity against a number of different Lactobacillus species and against Lactococcus lactis, streptococci and Staphylococcus aureus. It was found that LysA is 2 and 8000 times more active against L. fermentum than L. lactis and Streptococcus pyogenes, respectively. JF - FEMS Microbiology Letters AU - Turner, Mark S AU - Hafner, Louise M AU - Walsh, Terry AU - Giffard, Philip M AD - Infectious Diseases Program, Faculty of Science, School of Life Sciences, Queensland University of Technology, G.P.O. Box 2434, Brisbane, Queensland 4001, Australia, ms.turner@qut.edu.au Y1 - 2004/09/01/ PY - 2004 DA - 2004 Sep 01 SP - 9 EP - 15 VL - 238 IS - 1 SN - 0378-1097, 0378-1097 KW - streptococci KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus KW - Phages KW - Lactococcus lactis KW - Lactobacillus johnsonii KW - Amino acids KW - Lactobacillus plantarum KW - Cell envelopes KW - C-Terminus KW - Prophages KW - N-Terminus KW - Lytic enzymes KW - Lactobacillus fermentum KW - Escherichia coli KW - DNA KW - Lactobacillus gasseri KW - Open reading frames KW - Cell walls KW - J 02728:Enzymes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17757410?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Microbiology+Letters&rft.atitle=Identification%2C+characterisation+and+specificity+of+a+cell+wall+lytic+enzyme+from+Lactobacillus+fermentum+BR11&rft.au=Turner%2C+Mark+S%3BHafner%2C+Louise+M%3BWalsh%2C+Terry%3BGiffard%2C+Philip+M&rft.aulast=Turner&rft.aufirst=Mark&rft.date=2004-09-01&rft.volume=238&rft.issue=1&rft.spage=9&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Letters&rft.issn=03781097&rft_id=info:doi/10.1016%2Fj.femsle.2004.07.008 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Lytic enzymes; Phages; Amino acids; Cell envelopes; C-Terminus; DNA; Prophages; Open reading frames; N-Terminus; Cell walls; Streptococcus; Lactococcus lactis; Lactobacillus fermentum; Lactobacillus johnsonii; Lactobacillus plantarum; Escherichia coli; Lactobacillus gasseri DO - http://dx.doi.org/10.1016/j.femsle.2004.07.008 ER - TY - JOUR T1 - Improved non-viral transfection of glial and adult neural stem cell lines and of primary astrocytes by combining agents with complementary modes of action AN - 17512195; 6397262 AB - Background Rational design of gene vectors for therapeutic applications requires understanding of transfection mechanisms. In this study, multiple transfection assays revealed complementary mechanisms between two commonly used transfection agents. This finding was then exploited to produce improved transfection outcomes. Methods and results Rat C6 glial cells, adult rat hippocampal progenitor cells and primary astrocytes were transfected using Lipofectamine (LA) or polyethylenimine (PEI), in vitro. Although LA- and PEI-transfected populations expressed the same total level of transgene product. LA transfected considerably more cells than PEI (approximately 20 vs. 14%). A fluorescently labelled plasmid and time-course analysis, involving both flow cytometry and confocal microscopy, were used to explain this apparent discrepancy. Results showed that LA delivered more plasmid DNA to the cytoplasm and achieved transgene expression in more cells than PEI. In contrast, PEI transfected fewer cells but, on average, produced more transgene product per transfected cell. Conclusions A comparative transfection model was developed to explain these different characteristics. According to this model, transfection is a multistage process with different transfection agents exerting their primary effect at different stages in this process. This model forecast that it should be possible to prepare a chimeric complex with a transfection efficiency that exceeded that achievable with Lipofectamine or polyethylenimine alone. This prediction was tested and shown to hold for glioma cells, primary astrocytes, and adult neural stems cells. JF - Journal of Gene Medicine AU - Tinsley, R B AU - Vesey, MJ AU - Barati, S AU - Rush, R A AU - Ferguson, IA AD - Department of Human Physiology, School of Medicine, Flinders University of South Australia, GPO Box 2100, Adelaide, Australia, i.ferguson@flinders.edu.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1023 EP - 1032 VL - 6 IS - 9 SN - 1099-498X, 1099-498X KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Astrocytes KW - Hippocampus KW - Glial cells KW - Animal models KW - Flow cytometry KW - Stem cells KW - Cytoplasm KW - Glioma KW - Neuronal-glial interactions KW - Neural stem cells KW - Plasmids KW - Brain tumors KW - Transfection KW - W3 33181:Gene therapy vectors KW - W 30965:Miscellaneous, Reviews KW - W4 120:Genetic Engineering in Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17512195?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Gene+Medicine&rft.atitle=Improved+non-viral+transfection+of+glial+and+adult+neural+stem+cell+lines+and+of+primary+astrocytes+by+combining+agents+with+complementary+modes+of+action&rft.au=Tinsley%2C+R+B%3BVesey%2C+MJ%3BBarati%2C+S%3BRush%2C+R+A%3BFerguson%2C+IA&rft.aulast=Tinsley&rft.aufirst=R&rft.date=2004-09-01&rft.volume=6&rft.issue=9&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=Journal+of+Gene+Medicine&rft.issn=1099498X&rft_id=info:doi/10.1002%2Fjgm.584 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Transfection; Animal models; Astrocytes; Plasmids; Neural stem cells; Stem cells; Neuronal-glial interactions; Hippocampus; Flow cytometry; Glial cells; Cytoplasm; Glioma; Brain tumors DO - http://dx.doi.org/10.1002/jgm.584 ER - TY - JOUR T1 - Atmospheric Dispersion of Gases and Odours from Animal Production Systems AN - 16181423; 6109228 AB - Animal production systems are major agricultural sources of the greenhouse gases, methane and nitrous oxide, of pollutants such as ammonia and hydrogen sulfide, and of odours. Verifying inventory estimates of their production, and monitoring, regulating and reducing their emission all require the ability to make precise, non-obtrusive measurements of their fluxes, and in the case of odours, an ability to predict concentrations close to the source. However, these requirements present special problems. The source areas are often small or irregularly shaped, the sources may be distributed heterogeneously, and emissions may be transient. Odours present an additional problem in that it is difficult to quantify their intensity since they are usually due to a mixture of more than 100 volatile organic compounds. The use of tracer gases to follow odour dispersion is discussed, but quantifying odour intensity is a pressing problem. The paper considers measurement techniques appropriate for sources of different shapes and sizes. Most attention is given to small and irregularly shaped sources for which conventional, large-area micrometeorological approaches are inapplicable: line-sources, strips, small plots, and waste storage areas such as ponds and manure piles. Mass balance techniques appear to be particularly useful for these purposes. Various applications of the methodology are considered in some detail. The advent of open-path gas lasers that can measure concentrations rapidly and over distances of hundreds of meters is seen as a significant development. Finally, the paper considers the use of a Lagrangian dispersion model that allows emissions from sources of any geometry to be linked to concentrations at any location downwind. In forward mode, it can predict downwind concentrations for given source scenarios, while in backward mode, it can infer fluxes from measurements of concentration and wind speed at just one height downwind. It is a very attractive tool for use in many dispersion problems relevant to the theme of the paper. JF - Journal of Agricultural Meteorology AU - Denmead, O T AD - CSIRO Land and Water, GPO Box 1666, Canberra, ACT 2601, Australia Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 163 EP - 171 VL - 60 IS - 3 SN - 0021-8588, 0021-8588 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Laser observation of atmospheric composition KW - Agricultural pollution KW - Nitrous oxide emission control KW - Pollution dispersion KW - Odors KW - Animal ecology KW - Emission inventories KW - Ammonia emissions KW - Meteorology KW - Lagrangian characteristics KW - Hydrogen sulfide emissions KW - Wind KW - Odor dispersal KW - Methane KW - Methane emission control KW - Ammonia KW - Hydrogen sulfide KW - Livestock KW - Air pollution KW - Gases KW - Greenhouse gases KW - Trace gases dispersion KW - Dispersion models KW - Gas dispersion KW - Volatile organic compounds KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - M2 551.586:Biometeorology and Bioclimatology (551.586) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16181423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Meteorology&rft.atitle=Atmospheric+Dispersion+of+Gases+and+Odours+from+Animal+Production+Systems&rft.au=Denmead%2C+O+T&rft.aulast=Denmead&rft.aufirst=O&rft.date=2004-09-01&rft.volume=60&rft.issue=3&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Meteorology&rft.issn=00218588&rft_id=info:doi/ LA - Japanese DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-02-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Methane emission control; Laser observation of atmospheric composition; Nitrous oxide emission control; Ammonia emissions; Lagrangian characteristics; Dispersion models; Trace gases dispersion; Animal ecology; Hydrogen sulfide emissions; Gas dispersion; Odor dispersal; Methane; Agricultural pollution; Ammonia; Pollution dispersion; Hydrogen sulfide; Odors; Livestock; Air pollution; Emission inventories; Gases; Meteorology; Greenhouse gases; Volatile organic compounds; Wind ER - TY - JOUR T1 - Arctic National Wildlife Refuge (ANWR): Controversies for the 108th Congress AN - 14721229; 10673299 AB - Advocates of energy development in the Arctic National Wildlife Refuge (ANWR), AK, argue that such activity would reduce US dependence on oil imports with detriment to the environment. Opponents contend that intrusion on this ecosystem can not be justified on any terms, and that any oil found would provide little energy security. The first relevant vote in the 108th Congress came in March 2003, when language was stripped from the Senate Budget resolution that would have facilitated subsequent passage of ANWR development legislation. There is little potential for enactment of ANWR development legislation in the remainder of the 108th Congress. JF - US Congressional Research Service Report IB10111 AU - Corn, MLynne AU - Gelb, Bernard A AU - Baldwin, Pamela Y1 - 2004/09// PY - 2004 DA - Sep 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - COST BENEFIT ANALYSIS, OIL KW - LEGISLATION, FEDERAL KW - WILDLIFE REFUGES, FEDERAL KW - LAND USE PLANNING KW - OIL EXPLORATION, ONSHORE KW - ALASKA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14721229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10111&rft.atitle=Arctic+National+Wildlife+Refuge+%28ANWR%29%3A+Controversies+for+the+108th+Congress&rft.au=Corn%2C+MLynne%3BGelb%2C+Bernard+A%3BBaldwin%2C+Pamela&rft.aulast=Corn&rft.aufirst=MLynne&rft.date=2004-09-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10111&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - COST BENEFIT ANALYSIS, OIL; OIL EXPLORATION, ONSHORE; LEGISLATION, FEDERAL; WILDLIFE REFUGES, FEDERAL; ALASKA; LAND USE PLANNING ER - TY - JOUR T1 - Exhaled Breath Condensate as a Suitable Matrix to Assess Lung Dose and Effects in Workers Exposed to Cobalt and Tungsten AN - 14712549; 10668143 AB - Workers from three factories producing either diamond tools or hard-metal inserts were studied to examine whether exhaled breath condensate (EBC) could be used to assess risk of exposure to pneumotoxic metals. The workers were exposed to either cobalt or tungsten. Two EBC and two urinary samples were collected from each subject, one before and one at the end of the work shift, and concentrations of Co, W, and malondialdehyde in EBC were measured. Malondialdehyde was measured as a biomarker of pulmonary oxidative stress. Results showed that Co and W could be measured in EBC. No correlation was found between either urinary Co or urinary W and malondialdehyde concentration in EBC, but both Co and W in EBC were correlated with EBC malondialdehyde levels, which suggested that exhaled elements reflected the lung dose. JF - Environmental Health Perspectives AU - Goldoni, Matteo AU - Catalani, Simona AU - De Palma, Giuseppe AU - Manini, Paola AU - Acampa, Olga AU - Corradi, Massimo AU - Bergonzi, Roberto Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1293 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - BIOLOGICAL INDICATORS, AIR KW - AIR POLLUTION, INDOOR KW - COBALT KW - TUNGSTEN KW - OXIDANT STRESS KW - ALDEHYDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14712549?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Exhaled+Breath+Condensate+as+a+Suitable+Matrix+to+Assess+Lung+Dose+and+Effects+in+Workers+Exposed+to+Cobalt+and+Tungsten&rft.au=Goldoni%2C+Matteo%3BCatalani%2C+Simona%3BDe+Palma%2C+Giuseppe%3BManini%2C+Paola%3BAcampa%2C+Olga%3BCorradi%2C+Massimo%3BBergonzi%2C+Roberto&rft.aulast=Goldoni&rft.aufirst=Matteo&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1293&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; BIOLOGICAL INDICATORS, AIR; AIR POLLUTION, INDOOR; OXIDANT STRESS; TUNGSTEN; COBALT; ALDEHYDES ER - TY - JOUR T1 - Particulate Matter Exposure Impairs Systemic Microvascular Endothelium-Dependent Dilation AN - 14710319; 10668144 AB - The effects of pulmonary particulate matter (PM) exposure on systemic endothelium-dependent arteriolar dilation were investigated using intratracheal instillation and bronchoalveolar lavage in conjunction with intravital microscopy, which were used to study the effects of residual oil flyash exposure on microvascular function in the rat spinotrapezius muscle. Arterioles of the first branching order were studied because the vessels are responsible, along with their upstream feed arteries, for approximately 60% of total spinotrapezius muscular vascular resistance. Results showed that pulmonary PM exposure significantly impaired A23187-induced arteriolar endothelium-dependent dilation in the rat spinotrapezius muscle. Pulmonary PM exposure appeared to abolish both nitric oxide-dependent and -independent systemic arteriolar dilation, but exposure did not affect systemic arteriolar smooth muscle responsiveness to NO. Particulate matter exposure increased the number of adhering and rolling leukocytes in spinotrapezius muscle venules. A significant impairment of systemic arteriolar dilation was observed 24 h after intratracheal instillation of 0.1 mg residual oil flyash. JF - Environmental Health Perspectives AU - Nurkiewicz, Timothy R AU - Porter, Dale W AU - Barger, Mark AU - Castranova, Vincent AU - Boegehold, Matthew A Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1299 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - FLYASH KW - PULMONARY EFFECTS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710319?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Particulate+Matter+Exposure+Impairs+Systemic+Microvascular+Endothelium-Dependent+Dilation&rft.au=Nurkiewicz%2C+Timothy+R%3BPorter%2C+Dale+W%3BBarger%2C+Mark%3BCastranova%2C+Vincent%3BBoegehold%2C+Matthew+A&rft.aulast=Nurkiewicz&rft.aufirst=Timothy&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1299&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; FLYASH; PULMONARY EFFECTS; PARTICULATES ER - TY - JOUR T1 - Pesticide Product Use and Risk of Non-Hodgkin Lymphoma in Women AN - 14707838; 10668140 JF - Environmental Health Perspectives AU - Kato, Ikuko AU - Watanabe-Meserve, Hiroko AU - Baptiste, Mark S AU - Lillquist, Patricia P AU - Frizzera, Galuco AU - Burke, Jerome S Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1275 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - PESTICIDE USAGE, RESIDENTIAL KW - PESTICIDE USAGE KW - DISEASES AND DISORDERS KW - NEW YORK STATE KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707838?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pesticide+Product+Use+and+Risk+of+Non-Hodgkin+Lymphoma+in+Women&rft.au=Kato%2C+Ikuko%3BWatanabe-Meserve%2C+Hiroko%3BBaptiste%2C+Mark+S%3BLillquist%2C+Patricia+P%3BFrizzera%2C+Galuco%3BBurke%2C+Jerome+S&rft.aulast=Kato&rft.aufirst=Ikuko&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1275&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; PESTICIDE USAGE, RESIDENTIAL; DISEASES AND DISORDERS; NEW YORK STATE; PESTICIDE EXPOSURE; PESTICIDE USAGE ER - TY - JOUR T1 - The Science and Practice of Carcinogen Identification and Evaluation AN - 14707762; 10668139 JF - Environmental Health Perspectives AU - Cogliano, Vincent James AU - Baan, Robert A AU - Straif, Kurt AU - Grosse, Yann AU - Secretan, Marie Beatrice AU - El Ghissassi, Fatiha AU - Kleihues, Paul Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1269 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - CARCINOGENIC MECHANISMS KW - CARCINOGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707762?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Large+Effects+from+Small+Exposures.+I.+Mechanisms+for+Endocrine-Disrupting+Chemicals+with+Estrogenic+Activity&rft.au=Welshons%2C+W+V%3BThayer%2C+KA%3BJudy%2C+B+M%3BTaylor%2C+JA%3BCurran%2C+E+M%3BVom+Saal%2C+FS&rft.aulast=Welshons&rft.aufirst=W&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=994&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5494 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; CARCINOGENIC MECHANISMS; CARCINOGENIC AGENTS ER - TY - JOUR T1 - Neurologic Abnormalities in Workers of a 1-Bromopropane Factory AN - 14707462; 10668147 AB - Female workers in a 1-bromopropane production factory were examined in terms of neurologic function and other health related changes, and results were compared with those of control workers in a beer factory. Both factories were located in China. The medical examination, electrophysiologic studies, blood tests, and neurobehavioral tests conducted are detailed, along with the assessment of exposure to 1-bromopropane. Results showed that 1-bromopropane workers had significantly longer distal latency and lower sensory nerve conduction velocity than did age-matched controls. Neurobehavioral tests showed lower values for the forward and backward digit span, Benton visual memory test, pursuit aiming test, and Profile of Mood States test in the 1-bromopropane-exposed workers than in controls. JF - Environmental Health Perspectives AU - Ichihara, Gaku AU - Li, Weihua AU - Shibata, Eiji AU - Ding, Xuncheng AU - Wang, Hailan AU - Liang, Yideng AU - Peng, Simeng Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1319 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - SOLVENTS KW - NEUROTOXICITY KW - AIR POLLUTION, INDOOR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Neurologic+Abnormalities+in+Workers+of+a+1-Bromopropane+Factory&rft.au=Ichihara%2C+Gaku%3BLi%2C+Weihua%3BShibata%2C+Eiji%3BDing%2C+Xuncheng%3BWang%2C+Hailan%3BLiang%2C+Yideng%3BPeng%2C+Simeng&rft.aulast=Ichihara&rft.aufirst=Gaku&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1319&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOLVENTS; HEALTH SAFETY, OCCUPATIONAL; NEUROTOXICITY; AIR POLLUTION, INDOOR ER - TY - JOUR T1 - Effects of Low Sulfur Fuel and a Catalyzed Particle Trap on the Composition and Toxicity of Diesel Emissions AN - 14707413; 10668145 AB - Young C57B1/6 mice were exposed to diesel engine exhaust (DEE) or to DEE plus an emission-reduction method involving low-sulfur fuel and a catalyzed particle trap to assess the impact of such emission-reduction methods on the composition and toxicity of diesel emissions. Implementation of the low-S fuel/catalyzed trap combination decreased the concentrations of most components of emissions and diminished the biological effects of DEE on viral clearance, inflammation, and oxidative stress. The control method decreased nearly every measured exposure constituent, except for nitrogen oxides and selected individual organic compounds such as carbonyls, to background levels. JF - Environmental Health Perspectives AU - McDonald, Jacob D AU - Harrod, Kevin S AU - Seagrave, JeanClare AU - Seilkop, Steven K AU - Mauderly, Joe L Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1307 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DIESEL ENGINES KW - AUTOMOBILE EMISSIONS KW - FUEL CHEMISTRY KW - PARTICULATES KW - IMMUNE RESPONSE KW - PULMONARY EFFECTS KW - OXIDANT STRESS KW - AUTOMOBILE EMISSION CONTROL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+Low+Sulfur+Fuel+and+a+Catalyzed+Particle+Trap+on+the+Composition+and+Toxicity+of+Diesel+Emissions&rft.au=McDonald%2C+Jacob+D%3BHarrod%2C+Kevin+S%3BSeagrave%2C+JeanClare%3BSeilkop%2C+Steven+K%3BMauderly%2C+Joe+L&rft.aulast=McDonald&rft.aufirst=Jacob&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1307&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DIESEL ENGINES; FUEL CHEMISTRY; AUTOMOBILE EMISSIONS; OXIDANT STRESS; PULMONARY EFFECTS; AUTOMOBILE EMISSION CONTROL; PARTICULATES; IMMUNE RESPONSE ER - TY - JOUR T1 - Options for Managing Invasive Marine Species AN - 1034812789; 17024092 AB - Marine biological invasions are increasingly recognised as a threat to biodiversity and coastal industry, including fisheries. Globally, efforts are underway to contain, if not eradicate, several high-impact marine invasive species. However, working in a marine environment places unique social, political and technical constraints on options for pest control, which we explored in a series of stakeholder workshops. Results suggest that current efforts are low risk and publicly acceptable, but have a low probability of success against established invaders. However, techniques deemed likely to be successful and ultimately needed in a marine context are currently more contentious for social and political reasons. To control introduced marine pests, scientists and managers will need to overcome perceptual biases among marine stakeholders, develop a decision-making framework for what is perceived to be an open system, and focus on technologies likely to be both effective and publicly and politically acceptable. JF - Biological Invasions AU - Thresher, Ronald E AU - Kuris, Armand M AD - CSIRO Marine Research, G.P.O. Box 1538, Hobart, Tasmania, 7001, Australia, Ron.Thresher@csiro.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 295 EP - 300 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 6 IS - 3 SN - 1387-3547, 1387-3547 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Marine fisheries KW - Stakeholders KW - Politics KW - Biological diversity KW - Biodiversity KW - Fishery management KW - Marine environment KW - Risk factors KW - Fisheries KW - Invasions KW - Pests KW - Marine KW - Conferences KW - Invasive Species KW - Pest control KW - Rare species KW - Decision making KW - Perception KW - Nature conservation KW - Introduced species KW - Open systems KW - Technology KW - O 5080:Legal/Governmental KW - M3 1010:Issues in Sustainable Development KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034812789?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Invasions&rft.atitle=Options+for+Managing+Invasive+Marine+Species&rft.au=Thresher%2C+Ronald+E%3BKuris%2C+Armand+M&rft.aulast=Thresher&rft.aufirst=Ronald&rft.date=2004-09-01&rft.volume=6&rft.issue=3&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=Biological+Invasions&rft.issn=13873547&rft_id=info:doi/10.1023%2FB%3ABINV.0000034598.28718.2e LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - Marine fisheries; Fishery management; Invasive Species; Nature conservation; Biodiversity; Pest control; Rare species; Open systems; Introduced species; Decision making; Conferences; Marine environment; Risk factors; Fisheries; Invasions; Pests; Stakeholders; Perception; Politics; Biological diversity; Technology; Marine DO - http://dx.doi.org/10.1023/B:BINV.0000034598.28718.2e ER - TY - BOOK T1 - Environmental cleanup at Vieques Island and Culebra Island T2 - Mem. AN - 59964367; 2004-1003800 AB - Analyzes key issues regarding the cleanup of environmental contamination resulting from weapons training and other activities of the US Navy. JF - United States Congressional Research Service, August 19 2004. AU - Rearden, David M AU - Luther, Linda G Y1 - 2004/08/19/ PY - 2004 DA - 2004 Aug 19 PB - United States Congressional Research Service KW - United States -- Navy KW - Naval bases -- United States KW - Military training -- United States KW - Ordnance testing -- United States KW - Munitions -- United States KW - Vieques (island), Puerto Rico -- Environmental conditions KW - Environmental health -- Puerto Rico KW - Culebra (island), Puerto Rico -- Environmental conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59964367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Rearden%2C+David+M%3BLuther%2C+Linda+G&rft.aulast=Rearden&rft.aufirst=David&rft.date=2004-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Environmental+cleanup+at+Vieques+Island+and+Culebra+Island&rft.title=Environmental+cleanup+at+Vieques+Island+and+Culebra+Island&rft.issn=&rft_id=info:doi/ L2 - http://www.house.gov/serrano/pdf/vieques-culebra.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Cong Research Service N1 - Document feature - map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - CemaT1 is an active transposon within the Caenorhabditis elegans genome. AN - 66774103; 15302406 AB - The maT clade of transposons is a group of transposable elements intermediate in sequence and predicted protein structure to mariner and Tc transposons, with a distribution thus far limited to a few invertebrate species. In the nematode Caenorhabditis elegans, there are eight copies of CemaT1 that are predicted to encode a functional transposase, with five copies being >99% identical. We present evidence, based on searches of publicly available databases and on PCR-based mobility assays, that the CemaT1 transposase is expressed in C. elegans and that the CemaT transposons are capable of excising in both somatic and germline tissues. We also show that the frequency of CemaT1 excisions within the genome of the N2 strain of C. elegans is comparable to that of the Tc1 transposon. However, unlike Tc transposons in mutator strains of C. elegans, maT transposons do not exhibit increased frequencies of mobility, suggesting that maT is not regulated by the same factors that control Tc activity in these strains. Finally, we show that CemaT1 transposons are capable of precise transpositions as well as orientation inversions at some loci, and thereby become members of an increasing number of identified active transposons within the C. elegans genome. JF - Gene AU - Brownlie, J C AU - Whyard, S AD - Division of Entomology, CSIRO GPO Box 1700, Canberra ACT 2601, Australia. j.brownlie@uq.edu.au Y1 - 2004/08/18/ PY - 2004 DA - 2004 Aug 18 SP - 55 EP - 64 VL - 338 IS - 1 SN - 0378-1119, 0378-1119 KW - DNA Transposable Elements KW - 0 KW - Index Medicus KW - Animals KW - Base Sequence KW - Gene Expression KW - Germ-Line Mutation KW - Species Specificity KW - Mutation KW - Mutagenesis, Insertional KW - DNA Transposable Elements -- genetics KW - Genome KW - Caenorhabditis elegans -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66774103?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Gene&rft.atitle=CemaT1+is+an+active+transposon+within+the+Caenorhabditis+elegans+genome.&rft.au=Brownlie%2C+J+C%3BWhyard%2C+S&rft.aulast=Brownlie&rft.aufirst=J&rft.date=2004-08-18&rft.volume=338&rft.issue=1&rft.spage=55&rft.isbn=&rft.btitle=&rft.title=Gene&rft.issn=03781119&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-02 N1 - Date created - 2004-08-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - BOOK T1 - Abortion services and military medical facilities T2 - CRS rept. for Cong. Order code 95-387 F AN - 59931208; 2004-1008690 AB - Describes history of provisions to abortion services for military personnel and their dependents, and other military health care beneficiaries, with an emphasis on legislative actions; proposals to modify the law and related legislative and administrative actions; US. JF - United States Congressional Research Service, August 18 2004. AU - Burrelli, David f Y1 - 2004/08/18/ PY - 2004 DA - 2004 Aug 18 PB - United States Congressional Research Service KW - United States -- Armed forces -- Medical and sanitary affairs KW - Medicine, Military -- United States KW - Medical service -- Legal aspects KW - Abortion -- Regulation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59931208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Burrelli%2C+David+f&rft.aulast=Burrelli&rft.aufirst=David&rft.date=2004-08-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Abortion+services+and+military+medical+facilities&rft.title=Abortion+services+and+military+medical+facilities&rft.issn=&rft_id=info:doi/ L2 - http://www.law.umaryland.edu/marshall/ElectronicResources/crsreports/crsdocuments/95-387_F.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Cong Research Service N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Peak resolution and tailing in alpha-particle spectrometry for environmental samples. AN - 71996840; 15177338 AB - Peak resolution in alpha-particle spectrometry is generally quoted as full-width-at half maximum. However, the extent of tailing of alpha particle peaks into regions of lower energy is often a critical factor for accurate spectral analysis, particularly given the relatively low count rates observed for many environmental samples. In this paper we examine the influence of various factors on peak resolution and tailing for spectra collected using solid-state alpha detectors, in particular chamber gas pressure and source deposit thickness. JF - Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine AU - Martin, Paul AU - Hancock, Gary J AD - Environmental Research Institute of the Supervising Scientist, GPO Box 461, Darwin 0801, Australia. paul.martin@deh.gov.au PY - 2004 SP - 161 EP - 165 VL - 61 IS - 2-3 SN - 0969-8043, 0969-8043 KW - Environmental Pollutants KW - 0 KW - Radioisotopes KW - Index Medicus KW - Sensitivity and Specificity KW - Reproducibility of Results KW - Particle Size KW - Pressure KW - Artifacts KW - Radioisotopes -- chemistry KW - Spectrum Analysis -- methods KW - Alpha Particles KW - Radioisotopes -- analysis KW - Environmental Pollutants -- analysis KW - Radiometry -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71996840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+radiation+and+isotopes+%3A+including+data%2C+instrumentation+and+methods+for+use+in+agriculture%2C+industry+and+medicine&rft.atitle=Peak+resolution+and+tailing+in+alpha-particle+spectrometry+for+environmental+samples.&rft.au=Windham%2C+Gayle+C%3BWaller%2C+Kirsten%3BAnderson%2C+Meredith%3BFenster%2C+Laura%3BMendola%2C+Pauline%3BSwan%2C+Shanna&rft.aulast=Windham&rft.aufirst=Gayle&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=935&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-16 N1 - Date created - 2004-06-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - [Methods for protein purification from biological samples]. AN - 66889508; 15376965 JF - Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme AU - Araki, Norie AD - nori@gpo.kumamoto-u.ac.jp Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 1495 EP - 1505 VL - 49 IS - 11 Suppl SN - 0039-9450, 0039-9450 KW - Hazardous Substances KW - 0 KW - Proteins KW - Index Medicus KW - Sequence Analysis, Protein -- methods KW - Animals KW - Mass Spectrometry -- instrumentation KW - Electrophoresis -- methods KW - Humans KW - Mass Spectrometry -- methods KW - Chromatography -- methods KW - Sequence Analysis, Protein -- instrumentation KW - Proteins -- isolation & purification KW - Specimen Handling -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66889508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tanpakushitsu+kakusan+koso.+Protein%2C+nucleic+acid%2C+enzyme&rft.atitle=%5BMethods+for+protein+purification+from+biological+samples%5D.&rft.au=Araki%2C+Norie&rft.aulast=Araki&rft.aufirst=Norie&rft.date=2004-08-01&rft.volume=49&rft.issue=11+Suppl&rft.spage=1495&rft.isbn=&rft.btitle=&rft.title=Tanpakushitsu+kakusan+koso.+Protein%2C+nucleic+acid%2C+enzyme&rft.issn=00399450&rft_id=info:doi/ LA - Japanese DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-02 N1 - Date created - 2004-09-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Clonidine prolongation of lidocaine analgesia after sciatic nerve block in rats Is mediated via the hyperpolarization-activated cation current, not by alpha-adrenoreceptors. AN - 66743959; 15277933 AB - Although clonidine is commonly combined with local anesthetics to extend duration of peripheral nerve block, the mechanism by which clonidine potentiates local anesthetic action in vivo is unclear. Male Sprague-Dawley rats received percutaneous injections of 1% lidocaine with/without clonidine or epinephrine into the sciatic notch and duration of sensory blockade was quantified by inhibition of pinprick foot withdrawal. The antagonists prazosin or yohimbine were injected before lidocaine with clonidine or epinephrine to determine the role of alpha-adrenergic receptors. The role of the hyperpolarization-activated cation current (Ih) was evaluated by injecting the current blocker ZD 7288 as well as the current enhancers forskolin and 8-Br-cAMP before lidocaine alone or with 15 micrograms/ml clonidine. Mean duration of sensory block for lidocaine alone was 69 +/- 2 min. Sensory block duration increased monotonically with increasing doses of added clonidine or epinephrine. Preinjection of prazosin but not yohimbine prevented the increase in block duration seen with epinephrine. Neither alpha-adrenergic antagonist attenuated the extended duration of block with clonidine. ZD 7288 extended sensory blockade equivalent to the prolongation observed with clonidine. There was no additive effect when ZD 7288 and clonidine were combined, and a decreased duration of nerve block when either forskolin or 8-Br-cAMP preceded injection of lidocaine with clonidine. The findings indicate that prolongation of duration of in vivo lidocaine nerve blockade by clonidine is not mediated by an alpha-adrenergic mechanism but likely involves the Ih current. JF - Anesthesiology AU - Kroin, Jeffrey S AU - Buvanendran, Asokumar AU - Beck, Daniel R AU - Topic, Julie E AU - Watts, Daniel E AU - Tuman, Kenneth J AD - Department of Anesthesiology, Rush Medical College, 1653 W. Congress Parkway, Chicago, Illinois 60612, USA. jkroin@rush.edu Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 488 EP - 494 VL - 101 IS - 2 SN - 0003-3022, 0003-3022 KW - Adrenergic alpha-Agonists KW - 0 KW - Anesthetics, Local KW - Ion Channels KW - Pyrimidines KW - Receptors, Adrenergic, alpha KW - ICI D2788 KW - 133059-99-1 KW - Colforsin KW - 1F7A44V6OU KW - Lidocaine KW - 98PI200987 KW - Clonidine KW - MN3L5RMN02 KW - Epinephrine KW - YKH834O4BH KW - Abridged Index Medicus KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Colforsin -- pharmacology KW - Dose-Response Relationship, Drug KW - Epinephrine -- pharmacology KW - In Vitro Techniques KW - Receptors, Adrenergic, alpha -- drug effects KW - Pyrimidines -- pharmacology KW - Drug Synergism KW - Male KW - Lidocaine -- administration & dosage KW - Anesthetics, Local -- administration & dosage KW - Nerve Block KW - Ion Channels -- antagonists & inhibitors KW - Anesthetics, Local -- pharmacology KW - Adrenergic alpha-Agonists -- pharmacology KW - Clonidine -- administration & dosage KW - Adrenergic alpha-Agonists -- administration & dosage KW - Lidocaine -- pharmacology KW - Clonidine -- pharmacology KW - Sciatic Nerve -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66743959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Anesthesiology&rft.atitle=Clonidine+prolongation+of+lidocaine+analgesia+after+sciatic+nerve+block+in+rats+Is+mediated+via+the+hyperpolarization-activated+cation+current%2C+not+by+alpha-adrenoreceptors.&rft.au=Kroin%2C+Jeffrey+S%3BBuvanendran%2C+Asokumar%3BBeck%2C+Daniel+R%3BTopic%2C+Julie+E%3BWatts%2C+Daniel+E%3BTuman%2C+Kenneth+J&rft.aulast=Kroin&rft.aufirst=Jeffrey&rft.date=2004-08-01&rft.volume=101&rft.issue=2&rft.spage=488&rft.isbn=&rft.btitle=&rft.title=Anesthesiology&rft.issn=00033022&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-24 N1 - Date created - 2004-07-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Coenzyme Q10 and diabetic endotheliopathy: oxidative stress and the 'recoupling hypothesis'. AN - 66715906; 15256611 AB - Increased oxidative stress in diabetes mellitus may underlie the development of endothelial cell dysfunction by decreasing the availability of nitric oxide (NO) as well as by activating pro-inflammatory pathways. In the arterial wall, redox imbalance and oxidation of tetrahydrobiopterin (BH4) uncouples endothelial nitric oxide synthase (eNOS). This results in decreased production and increased consumption of NO, and generation of free radicals, such as superoxide and peroxynitrite. In the mitochondria, increased redox potential uncouples oxidative phosphorylation, resulting in inhibition of electron transport and increased transfer of electrons to molecular oxygen to form superoxide and other oxidant radicals. Coenzyme Q10 (CoQ), a potent antioxidant and a critical intermediate of the electron transport chain, may improve endothelial dysfunction by 'recoupling' eNOS and mitochondrial oxidative phosphorylation. CoQ supplementation may also act synergistically with anti-atherogenic agents, such as fibrates and statins, to improve endotheliopathy in diabetes. JF - QJM : monthly journal of the Association of Physicians AU - Chew, G T AU - Watts, G F AD - School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, GPO Box X2213, Perth, Western Australia, Australia 6847. Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 537 EP - 548 VL - 97 IS - 8 SN - 1460-2725, 1460-2725 KW - Antioxidants KW - 0 KW - Coenzymes KW - Receptors, Cytoplasmic and Nuclear KW - Transcription Factors KW - Ubiquinone KW - 1339-63-5 KW - Nitric Oxide KW - 31C4KY9ESH KW - NOS3 protein, human KW - EC 1.14.13.39 KW - Nitric Oxide Synthase KW - Nitric Oxide Synthase Type III KW - coenzyme Q10 KW - EJ27X76M46 KW - Index Medicus KW - Endothelium, Vascular -- enzymology KW - Transcription Factors -- metabolism KW - Humans KW - Diabetic Angiopathies -- enzymology KW - Antioxidants -- metabolism KW - Phosphorylation KW - Receptors, Cytoplasmic and Nuclear -- metabolism KW - Diabetic Angiopathies -- drug therapy KW - Mitochondria -- metabolism KW - Dietary Supplements KW - Drug Synergism KW - Diabetic Angiopathies -- prevention & control KW - Diabetes Mellitus, Type 2 -- drug therapy KW - Ubiquinone -- administration & dosage KW - Oxidative Stress -- physiology KW - Diabetes Mellitus, Type 2 -- enzymology KW - Ubiquinone -- metabolism KW - Nitric Oxide -- metabolism KW - Nitric Oxide Synthase -- metabolism KW - Diabetes Mellitus, Type 2 -- prevention & control KW - Ubiquinone -- analogs & derivatives UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66715906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=QJM+%3A+monthly+journal+of+the+Association+of+Physicians&rft.atitle=Coenzyme+Q10+and+diabetic+endotheliopathy%3A+oxidative+stress+and+the+%27recoupling+hypothesis%27.&rft.au=Chew%2C+G+T%3BWatts%2C+G+F&rft.aulast=Chew&rft.aufirst=G&rft.date=2004-08-01&rft.volume=97&rft.issue=8&rft.spage=537&rft.isbn=&rft.btitle=&rft.title=QJM+%3A+monthly+journal+of+the+Association+of+Physicians&rft.issn=14602725&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-16 N1 - Date created - 2004-07-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Acetylation of raw cotton for oil spill cleanup application: an FTIR and 13C MAS NMR spectroscopic investigation. AN - 66705676; 15249021 AB - Fourier transform infrared (FTIR) and 13C MAS NMR spectroscopy have been used to investigate the acetylation of raw cotton samples with acetic anhydride without solvents in the presence of different amounts of 4-dimethylaminopyridine (DMAP) catalyst. This is a continuation of our previous investigation of acetylation of commercial cotton in an effort to develop hydrophobic, biodegradable, cellulosic sorbent materials for cleaning up oil spills. The FTIR data have again provided a clear evidence for successful acetylation. The NMR results further confirm the successful acetylation. The extent of acetylation was quantitatively determined using the weight percent gain (WPG) due to acetylation and by calculating the ratio R between the intensity of the acetyl C=O stretching band at 1740-1745 cm(-1) and the intensity of C-O stretching vibration of the cellulose backbone at about 1020-1040 cm(-1). The FTIR technique was found to be highly sensitive and reliable for the determination of the extent of acetylation. The level of acetylation of the raw cotton samples was found to be much higher than that of cotton fabrics and the previously studied commercial cotton. The variation of the R and WPG with reaction time, amount of DMAP catalyst and different samples of raw cotton is discussed. JF - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy AU - Adebajo, Moses O AU - Frost, Ray L AD - Inorganic Materials Research Program, School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane Qld 4001, Australia. m.adebajo@qut.edu.au Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 2315 EP - 2321 VL - 60 IS - 10 SN - 1386-1425, 1386-1425 KW - Acetic Anhydrides KW - 0 KW - Carbon Isotopes KW - Petroleum KW - Water Pollutants, Chemical KW - acetic anhydride KW - 2E48G1QI9Q KW - 4-Aminopyridine KW - BH3B64OKL9 KW - 4-dimethylaminopyridine KW - PFP1R6P0S8 KW - Index Medicus KW - Spectroscopy, Fourier Transform Infrared KW - Acetylation KW - Magnetic Resonance Spectroscopy KW - Acetic Anhydrides -- chemistry KW - 4-Aminopyridine -- chemistry KW - 4-Aminopyridine -- analogs & derivatives KW - Cotton Fiber UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66705676?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.atitle=Acetylation+of+raw+cotton+for+oil+spill+cleanup+application%3A+an+FTIR+and+13C+MAS+NMR+spectroscopic+investigation.&rft.au=Adebajo%2C+Moses+O%3BFrost%2C+Ray+L&rft.aulast=Adebajo&rft.aufirst=Moses&rft.date=2004-08-01&rft.volume=60&rft.issue=10&rft.spage=2315&rft.isbn=&rft.btitle=&rft.title=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.issn=13861425&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-03-01 N1 - Date created - 2004-07-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hemispheric correlation with psychomotor learning in manual communication tasks TT - Correlacion entre hemisfericidad y el aprendisaje psicomotor en lastareas de comunicaion cestual AN - 20966805; 7301949 AB - The objective of this study was to establish a correlation between hemispheres andthe psychomotor learning in connection with the gesture communication. According to Moura (1993), when the gesture communication is practiced, especially in the Brazilian Sign Language (LIBRAS), each of the brain hemispheres of the listening person reveals a decode predominantly different Therefore, left hemisphere prevails the linguistic functions, and right hemisphere the space-vision. In this survey we had the participation of one hundred students of both sexes, between 15 and 17 years old, with high school level attending one private school in the city of Rio de Janeiro. Once selected, the group was submitted to the CLEM TEST to identify the preference of the hemisphere processing. The students were divided in three hemispheric groups, that is, the right hemisphere (HR), the left hemisphere (HL) and the bi-hemispheres (HRL).The components of each group were then submitted to a individual selective test including significative competency in relation to the communicative gestures signs. Analysis of variance was performed between the three groups (p < 0,05). The especific sign, regarding the performance of each student, indicated evidences that the linguistics aspects are preferably processed in the left hemisphere. JF - Fitness and Performance Journal AU - Vallado, SY AU - de Delgado, GPO AU - de Souza, DOR AU - Guagliardi, Jr AU - da Silva, VF AU - Lins, FRW AD - Rua Rainha Guilhermina, 131, apto. 305 - Leblon - Rio de Janeiro - Cep 22441-120, soniavallado@ig.com.br Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 207 EP - 210 VL - 3 IS - 4 SN - 1519-9088, 1519-9088 KW - Physical Education Index; CSA Neurosciences Abstracts KW - High school students KW - Fitness KW - Hemispheric laterality KW - Learning KW - Cerebral hemispheres KW - Communication KW - Brain KW - Surveys KW - Private schools KW - Participation KW - Analysis KW - Language KW - Performance KW - Sex KW - N3 11001:Behavioral and Cognitive Neuroscience KW - PE 080:Motor Learning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20966805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fitness+and+Performance+Journal&rft.atitle=Hemispheric+correlation+with+psychomotor+learning+in+manual+communication+tasks&rft.au=Vallado%2C+SY%3Bde+Delgado%2C+GPO%3Bde+Souza%2C+DOR%3BGuagliardi%2C+Jr%3Bda+Silva%2C+VF%3BLins%2C+FRW&rft.aulast=Vallado&rft.aufirst=SY&rft.date=2004-08-01&rft.volume=3&rft.issue=4&rft.spage=207&rft.isbn=&rft.btitle=&rft.title=Fitness+and+Performance+Journal&rft.issn=15199088&rft_id=info:doi/ LA - Portuguese DB - Physical Education Index N1 - Date revised - 2007-04-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Fitness; High school students; Learning; Private schools; Participation; Analysis; Brain; Communication; Surveys; Performance; Sex; Hemispheric laterality; Cerebral hemispheres; Language ER - TY - JOUR T1 - Nutrients for Cognitive Development in School-aged Children AN - 20411306; 9084802 AB - This review considers the research to date on the role of nutrition in cognitive development in children, with a particular emphasis on the relatively neglected post-infancy period. Undernutrition and deficiencies of iodine, iron, and folate are all important for the development of the brain and the emergent cognitive functions, and there is some evidence to suggest that zinc, vitamin B12, and omega-3 polyunsaturated fatty acids may also be important. Considerations for future research include a focus on the interactions between micronutrients and macronutrients that might be influential in the optimization of cognitive development; investigation of the impact of nutritional factors in children after infancy, with particular emphasis on effects on the developing executive functions; and selection of populations that might benefit from nutritional interventions, for example, children with nutrient deficiencies or those suffering from attention deficit-hyperactivity disorder and dyslexia. JF - Nutrition Reviews AU - Janet, Bryan AU - Saskia, Osendarp AU - Donna, Hughes AU - Eva, Calvaresi AU - Katrine, Baghurst AU - Jan-Willem, van Klinken AD - CSIRO, Health Sciences and Nutrition, GPO Box 10041, Adelaide BC, South Australia, 5000 Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 295 EP - 306 PB - International Life Sciences Institute, PO Box 1897 Lawrence KS 66044-8897 USA, [mailto:ilsi@ilsi.org], [URL:http://www.ilsi.org] VL - 62 IS - 8 SN - 0029-6643, 0029-6643 KW - Pollution Abstracts; CSA Neurosciences Abstracts KW - NUTRITION KW - COGNITION KW - CHILDREN KW - MICRONUTRIENTS KW - BRAIN DEVELOPMENT KW - Undernutrition KW - Nutrients KW - polyunsaturated fatty acids KW - Nutrition KW - vitamins KW - intervention KW - Zinc KW - Iodine KW - Micronutrients KW - Folic acid KW - micronutrients KW - Brain KW - Dyslexia KW - Children KW - Executive function KW - nutrients KW - Nutrient deficiency KW - cognitive ability KW - Vitamin B12 KW - Cognitive ability KW - Reviews KW - nutrient deficiency KW - Polyunsaturated fatty acids KW - Attention KW - Iron KW - N3 11001:Behavioral and Cognitive Neuroscience KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20411306?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nutrition+Reviews&rft.atitle=Nutrients+for+Cognitive+Development+in+School-aged+Children&rft.au=Janet%2C+Bryan%3BSaskia%2C+Osendarp%3BDonna%2C+Hughes%3BEva%2C+Calvaresi%3BKatrine%2C+Baghurst%3BJan-Willem%2C+van+Klinken&rft.aulast=Janet&rft.aufirst=Bryan&rft.date=2004-08-01&rft.volume=62&rft.issue=8&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=Nutrition+Reviews&rft.issn=00296643&rft_id=info:doi/10.1301%2Fnr.2004.aug.295-306 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-03-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Undernutrition; Brain; Dyslexia; Nutrients; Children; Nutrition; Executive function; Nutrient deficiency; Vitamin B12; Cognitive ability; Zinc; Iodine; Polyunsaturated fatty acids; Micronutrients; Folic acid; Iron; Attention; micronutrients; polyunsaturated fatty acids; nutrients; vitamins; cognitive ability; Reviews; intervention; nutrient deficiency DO - http://dx.doi.org/10.1301/nr.2004.aug.295-306 ER - TY - JOUR T1 - Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coli AN - 20193390; 5970646 JF - Analytical Biochemistry AU - Uchimura, Y AU - Nakamura, M AU - Sugasawa, K AU - Nakao, M AU - Saitoh, H AD - Department of Regeneration Medicine, Institute of Molecular Embryology Genetics, Kumamoto University, Kumamoto, 860-0811, Japan, hisa@gpo.kumamoto-u.ac.jp Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 204 EP - 206 PB - Academic Press, Inc., 525 B St. Ste. 1900 San Diego CA 92101-4495 USA, [mailto:apsubs@acad.com] VL - 331 IS - 1 SN - 0003-2697, 0003-2697 KW - Microbiology Abstracts B: Bacteriology KW - Biochemistry KW - Escherichia coli KW - J 02490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20193390?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+Biochemistry&rft.atitle=Overproduction+of+eukaryotic+SUMO-1-+and+SUMO-2-conjugated+proteins+in+Escherichia+coli&rft.au=Uchimura%2C+Y%3BNakamura%2C+M%3BSugasawa%2C+K%3BNakao%2C+M%3BSaitoh%2C+H&rft.aulast=Uchimura&rft.aufirst=Y&rft.date=2004-08-01&rft.volume=331&rft.issue=1&rft.spage=204&rft.isbn=&rft.btitle=&rft.title=Analytical+Biochemistry&rft.issn=00032697&rft_id=info:doi/10.1016%2Fj.ab.2004.04.034 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Biochemistry; Escherichia coli DO - http://dx.doi.org/10.1016/j.ab.2004.04.034 ER - TY - JOUR T1 - Framework for soil suitability evaluation for sewage effluent renovation AN - 19933232; 6018958 AB - Current methods of establishing suitable locations for onsite wastewater treatment systems (OWTS) are inadequate, particularly in light of the numerous cases of onsite system failure and the resulting adverse consequences. The development of a soil suitability framework for assessing soil suitability for OWTS allows a more practical means of assessment. The use of multivariate statistical analysis techniques, including Principal Component Analysis (PCA) and multi-criteria decision aids of PROMETHEE and GAIA, enabled the identification of suitable soils for effluent renovation. The outcome of the multivariate analysis, together with soil permeability and drainage characteristics permitted the establishment of a framework for assessing soil suitability based on three main soil functions: (1) the ability of the soil to provide suitable effluent renovation, (2) the permeability of the soil, and (3) the soil's drainage characteristics. The developed framework was subsequently applied to the research area, Gold Coast, Queensland, Australia, and the use of standard scoring functions were utilised to provide a scoring system to signify which soils were more suitable for effluent renovation processes. From the assessment, it was found that Chromosol and Kurosol soils provided the highest level of effluent renovation, closely followed by Ferrosol and Dermosol, Kandosol and Rudosol soil types. Tennosol and Podosol soil types were found to have a significantly lower suitability, with Hydrosol soils proving the least suitable for renovating effluent from OWTS. JF - Environmental Geology AU - Carroll, S AU - Goonetilleke, A AU - Dawes, L AD - School of Civil Engineering, Queensland University of Technology, GPO Box 2434, 4001, Brisbane, Australia, s.carroll@qut.edu.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 195 EP - 208 PB - Springer-Verlag VL - 46 IS - 2 SN - 0943-0105, 0943-0105 KW - Water Resources Abstracts KW - Land Disposal KW - Drainage KW - Principal Component Analysis KW - Effluents KW - Multivariate Analysis KW - Evaluation KW - Permeability KW - Assessments KW - Australia, Queensland, Gold Coast KW - Statistical Analysis KW - Soil Types KW - Wastewater Disposal KW - Standards KW - Wastewater Treatment KW - Coasts KW - SW 3040:Wastewater treatment processes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19933232?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Geology&rft.atitle=Framework+for+soil+suitability+evaluation+for+sewage+effluent+renovation&rft.au=Carroll%2C+S%3BGoonetilleke%2C+A%3BDawes%2C+L&rft.aulast=Carroll&rft.aufirst=S&rft.date=2004-08-01&rft.volume=46&rft.issue=2&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Environmental+Geology&rft.issn=09430105&rft_id=info:doi/10.1007%2Fs00254-004-1026-z L2 - http://link.springer.de/link/service/journals/00254/bibs/4046002/40460195.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-11-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Drainage; Land Disposal; Principal Component Analysis; Effluents; Multivariate Analysis; Evaluation; Permeability; Assessments; Soil Types; Statistical Analysis; Wastewater Disposal; Standards; Wastewater Treatment; Coasts; Australia, Queensland, Gold Coast DO - http://dx.doi.org/10.1007/s00254-004-1026-z ER - TY - JOUR T1 - Sulphur and nitrogen nutrition influence the response of chickpea seeds to an added, transgenic sink for organic sulphur AN - 19806671; 5986236 AB - In order to increase the concentration of the nutritionally essential sulphur amino acids in seed protein, a transgene encoding a methionine- and cysteine-rich protein, sunflower seed albumin (SSA), was transferred to chickpeas (Cicer arietinum L). Transgenic seeds that accumulated SSA contained more methionine and less oxidized sulphur than the controls, suggesting that additional demand for sulphur amino acids from the expression of the transgene stimulated sulphur assimilation. In addition, the activity of trypsin inhibitors, a known family of endogenous, sulphur-rich chickpea seed proteins, was diminished in transgenic, SSA-containing seeds compared with the non- transgenic controls. Together, these results indicate that the reduced sulphur sequestered into SSA was supplied partly by additional sulphur assimilation in the developing transgenic seeds, and partly by some diversion of sulphur amino acids from endogenous seed proteins. Growth of chickpeas on nutrient with a high sulphur-to-nitrogen ratio increased the total seed sulphur content and the accumulation of sulphur amino acids in the seeds, and partly mitigated the effect of SSA accumulation on the trypsin inhibitor amount. The results suggest that free methionine and O-acetylserine (OAS) acted as signals that modulated chickpea seed protein composition in response to the variation in sulphur demand, as well as in response to variation in the nitrogen and sulphur status of the plant. JF - Journal of Experimental Botany AU - Chiaiese, Pasquale AU - Ohkama-Ohtsu, Naoko AU - Molvig, Lisa AU - Godfree, Robert AU - Dove, Hugh AU - Hocart, Charles AU - Fujiwara, Toru AU - Higgins, TJV AU - Tabe, Linda M AD - CSIRO Plant Industry, GPO Box 1600 Canberra ACT 2601, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1889 EP - 1901 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 55 IS - 404 SN - 0022-0957, 0022-0957 KW - Biotechnology and Bioengineering Abstracts KW - Sulfur KW - Cicer arietinum KW - Seeds KW - Amino acids KW - Trypsin KW - Nutrients KW - Nutrition KW - Methionine KW - Albumin KW - Protein composition KW - Helianthus KW - Nitrogen KW - W 30925:Genetic Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19806671?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Botany&rft.atitle=Sulphur+and+nitrogen+nutrition+influence+the+response+of+chickpea+seeds+to+an+added%2C+transgenic+sink+for+organic+sulphur&rft.au=Chiaiese%2C+Pasquale%3BOhkama-Ohtsu%2C+Naoko%3BMolvig%2C+Lisa%3BGodfree%2C+Robert%3BDove%2C+Hugh%3BHocart%2C+Charles%3BFujiwara%2C+Toru%3BHiggins%2C+TJV%3BTabe%2C+Linda+M&rft.aulast=Chiaiese&rft.aufirst=Pasquale&rft.date=2004-08-01&rft.volume=55&rft.issue=404&rft.spage=1889&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Botany&rft.issn=00220957&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Sulfur; Seeds; Amino acids; Trypsin; Albumin; Protein composition; Nutrients; Nutrition; Methionine; Nitrogen; Cicer arietinum; Helianthus ER - TY - JOUR T1 - Transgenic chickpea seeds expressing high levels of a bean alpha -amylase inhibitor AN - 18063518; 6039376 AB - We describe a robust and reproducible Agrobacterium-mediated chickpea transformation method based on kanamycin selection, and its use to introduce the bean alpha AI1 gene into a desi type of chickpea. Bean alpha AI1 was specifically expressed in the seeds, accumulated up to 4.2% of seed protein and was processed to low molecular weight polypeptides as occurs in bean seeds. The transgenic protein was active as an inhibitor of porcine alpha -amylase in vitro. Transgenic chickpeas containing alpha -AI1 strongly inhibited the development of Callosobruchus maculatus and C. chinensis (Col. : Bruchidae) in insect bioassays. JF - Molecular Breeding AU - Sarmah, B K AU - Moore, A AU - Tate, W AU - Molvig, L AU - Morton, R L AU - Rees, D P AU - Chiaiese, P AU - Chrispeels, MJ AU - Tabe, L M AU - Higgins, T AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia; Current address: Department of Agricultural Biotechnology, Assam Agricultural University, Jorhat 785 013, India Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 73 EP - 82 PB - Kluwer Academic Publishers VL - 14 IS - 1 SN - 1380-3743, 1380-3743 KW - Chickpea KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Bioengineering Abstracts; Genetics Abstracts KW - Cicer arietinum KW - ^a-Amylase KW - Plant breeding KW - Transgenic plants KW - Reproductive strategy KW - Callosobruchus chinensis KW - Agrobacterium KW - a-Amylase KW - Callosobruchus maculatus KW - W2 32065:Plants KW - G 07354:Dicotyledons (crops) KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18063518?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+Breeding&rft.atitle=Transgenic+chickpea+seeds+expressing+high+levels+of+a+bean+alpha+-amylase+inhibitor&rft.au=Sarmah%2C+B+K%3BMoore%2C+A%3BTate%2C+W%3BMolvig%2C+L%3BMorton%2C+R+L%3BRees%2C+D+P%3BChiaiese%2C+P%3BChrispeels%2C+MJ%3BTabe%2C+L+M%3BHiggins%2C+T&rft.aulast=Sarmah&rft.aufirst=B&rft.date=2004-08-01&rft.volume=14&rft.issue=1&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Molecular+Breeding&rft.issn=13803743&rft_id=info:doi/10.1023%2FB%3AMOLB.0000037996.01494.12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Agrobacterium; Callosobruchus maculatus; Callosobruchus chinensis; Cicer arietinum; Plant breeding; a-Amylase; Reproductive strategy; Transgenic plants; ^a-Amylase DO - http://dx.doi.org/10.1023/B:MOLB.0000037996.01494.12 ER - TY - JOUR T1 - Effects of spatial resolution on the performance and interpretation of marine ecosystem models AN - 18054423; 5924394 AB - Simplifying models by using coarse spatial resolution can be desirable because it reduces structural, computational and data requirements and can make model interpretation easier. However, spatially simplified models may be incapable of reproducing important dynamics observed in nature. To consider this issue the effect of spatial structure on the output of two trophic ecosystem models (Bay Model 2 (BM2) and the Integrated Generic Bay Ecosystem Model (IGBEM)) was considered using a theoretical approach known as 'deep-shallow model' comparison. This involved comparing simulation runs of 1-, 3-, and 8-box versions of the ecosystem models (the 'shallow' models) with a 59-box version that was used to represent the real world (the 'deep' model). The results indicate that simpler spatial configurations (geometries) can result in less short-term variation, changes in predicted spatial patterns and trophic self- simplification (loss of functional groups), as the opportunity for spatial refuges is reduced. More importantly, models with very little spatial resolution (i.e. 1- and 3-box models) do not capture the effects of changes in nutrient loads or fishing pressure as well as more complex models. The results for the 8- box models used here indicate that some simplification is acceptable, as overall model performance is not overwhelmed by the impacts of trophic self- simplification and a loss of spatial heterogeneity. However, using models with very little spatial resolution (i.e. 1- and 3-box models) can be misleading, as the impacts on system dynamics of the reduced heterogeneity increase. JF - Ecological Modelling AU - Fulton, E A AU - Smith, ADM AU - Johnson, C R AD - CSIRO Division of Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, beth.fulton@csiro.au Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 27 EP - 42 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 176 IS - 1-2 SN - 0304-3800, 0304-3800 KW - Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Spatial structure KW - Biogeochemistry KW - Ecosystems KW - Models KW - Spatial variations KW - Marine KW - Marine environment KW - Ecological distribution KW - Simulation KW - Marine ecology KW - Marine ecosystems KW - Trophic relationships KW - Ecosystem models KW - Modelling KW - Q1 08482:Ecosystems and energetics KW - D 04003:Modeling, mathematics, computer applications KW - O 1090:Instruments/Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18054423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Effects+of+spatial+resolution+on+the+performance+and+interpretation+of+marine+ecosystem+models&rft.au=Fulton%2C+E+A%3BSmith%2C+ADM%3BJohnson%2C+C+R&rft.aulast=Fulton&rft.aufirst=E&rft.date=2004-08-01&rft.volume=176&rft.issue=1-2&rft.spage=27&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.10.026 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Spatial variations; Ecosystems; Marine environment; Ecological distribution; Marine ecology; Simulation; Trophic relationships; Modelling; Marine ecosystems; Ecosystem models; Marine DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.10.026 ER - TY - JOUR T1 - Burr medic (Medicago polymorpha L.) selections for improved N sub(2) fixation with naturalised soil rhizobia AN - 18043898; 5985238 AB - Burr medic (Medicago polymorpha L.) is an annual pasture legume that is widely distributed in southern Australian farming systems. Burr medic is nodulated by rhizobia (Sinorhizobium meliloti and Sinorhizobium medicae) that reside in many Australian soils, but the symbioses that develop are often sub-optimal in their rate of N sub(2) fixation. We attempted to identify burr medic lines, which are able to form effective symbioses with the naturalised Sinorhizobium in Australian field soils, as potential parents for a breeding program. There were three glasshouse experiments. Initially, 222 lines (including the M. polymorpha cvv. Santiago, Serena and Circle Valley) were inoculated with extracts of two soils that had been collected near Waikerie (soil S109) and Lochiel (soil S142) in South Australia. These soils were used because they contained numerically large communities of naturalised Sinorhizobium spp. that produced sub-optimal rates of N sub(2) fixation with cv. Santiago. None of the 222 lines of burr medic were able to form an effective symbiosis with the rhizobia from soil S109. However, when nodulated by the rhizobia from soil S142, some lines (e.g. SA8194) formed a very effective symbiosis, producing up to double the shoot dry matter (DM) of Santiago and eight times the DM of uninoculated plants. Seven promising lines were selected for further testing (with extracts of nine soils). Subsequently, two lines (SA20056 and SA8194) were selected and their symbiotic performance compared with that of Santiago, using extracts from 28 soils. While soil treatment had a major effect on mean shoot DM (soil N103=120 mg, soil N105=17 mg), the three medic lines performed similarly. Santiago, SA20056 and SA8914 all formed ineffective symbioses with the rhizobia in at least half of the 28 soils, even though >95% of the plants were nodulated. These experiments confirm that ineffective symbioses are common between burr medics and the rhizobia that have become naturalised in many Australian soils. Although some lines of burr medic were identified that were able to form more effective symbioses with the rhizobia in individual soils, none were able to form effective symbioses with a wide range of soil rhizobia. If a plant breeding approach is to be used to improve symbiotic performance of burr medic we propose that its hybridisation with other medic species, that have less specific rhizobial needs, will be required. JF - Soil Biology and Biochemistry AU - Charman, N AU - Ballard, R A AD - South Australian Research and Development Institute, GPO Box 397, Adelaide, SA 5001, Australia, charman.nigel@saugov.sa.gov.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1331 EP - 1337 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 36 IS - 8 SN - 0038-0717, 0038-0717 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Soil KW - Symbiosis KW - Nitrogen fixation KW - Breeding KW - Medicago polymorpha KW - Hybridization KW - Sinorhizobium medicae KW - Selection KW - Nitrogen KW - A 01051:Nitrogen cycle UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18043898?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Soil+Biology+and+Biochemistry&rft.atitle=Burr+medic+%28Medicago+polymorpha+L.%29+selections+for+improved+N+sub%282%29+fixation+with+naturalised+soil+rhizobia&rft.au=Charman%2C+N%3BBallard%2C+R+A&rft.aulast=Charman&rft.aufirst=N&rft.date=2004-08-01&rft.volume=36&rft.issue=8&rft.spage=1331&rft.isbn=&rft.btitle=&rft.title=Soil+Biology+and+Biochemistry&rft.issn=00380717&rft_id=info:doi/10.1016%2Fj.soilbio.2004.04.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Medicago polymorpha; Sinorhizobium medicae; Nitrogen; Symbiosis; Breeding; Hybridization; Soil; Nitrogen fixation; Selection DO - http://dx.doi.org/10.1016/j.soilbio.2004.04.014 ER - TY - JOUR T1 - Factors affecting abundance and oviposition rates of a field population of the Old World screw-worm fly, Chrysomya bezziana (Diptera: Calliphoridae) AN - 18034124; 5998226 AB - Sentinel cattle and a grid of swormlure-baited sticky traps were used to monitor a Malaysian population of the Old World screwworm fly, Chrysomya bezziana Villeneuve. Observations were carried out on an isolated cattle station at monthly intervals during the period August 1996 to June 2000. The number of flies caught was unaffected by weather conditions at the time of trapping, but was positively correlated with the total rainfall and the average daily air temperature prevailing 15-28 days earlier, when trapped flies were still juveniles. Trap catches were biased in favor of females, but daily catch rates of both sexes increased significantly the longer traps were open, suggesting that efficacy was related to the differential volatility of the chemicals comprising swormlure. Oviposition on sentinel cattle occurred mostly in late afternoon or early evening but increased significantly as the wound aged. Oviposition rates were positively correlated with female catch rates, but the relationship was curvilinear, suggesting that fly populations may be subject to some form of density-dependent constraint. Consistent differences in oviposition rates on sentinel cattle at different localities on the cattle station suggested the existence of highly clumped, quasi-stationary populations. Differences in trap catches between traps located in pastoral areas and those sited in nearby oil palm or rubber plantations supported this interpretation of the data. These findings are discussed in relation to the use of the sterile insect technique for the control of screwworm fly infestations. JF - Bulletin of Entomological Research AU - Mahon, R J AU - Ahmad, H AU - Wardhaugh, K G AD - CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 359 EP - 368 PB - CAB International VL - 94 IS - 4 SN - 0007-4853, 0007-4853 KW - cattle KW - Diptera KW - Blowflies KW - Animal Behavior Abstracts; Ecology Abstracts; Entomology Abstracts KW - Abundance KW - Climatic conditions KW - Bait KW - Chrysomya bezziana KW - Traps KW - Oviposition KW - Calliphoridae KW - D 04659:Insects KW - Z 05206:Medical & veterinary entomology KW - Y 25423:Insects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18034124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+Entomological+Research&rft.atitle=Factors+affecting+abundance+and+oviposition+rates+of+a+field+population+of+the+Old+World+screw-worm+fly%2C+Chrysomya+bezziana+%28Diptera%3A+Calliphoridae%29&rft.au=Mahon%2C+R+J%3BAhmad%2C+H%3BWardhaugh%2C+K+G&rft.aulast=Mahon&rft.aufirst=R&rft.date=2004-08-01&rft.volume=94&rft.issue=4&rft.spage=359&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+Entomological+Research&rft.issn=00074853&rft_id=info:doi/10.1079%2FBER2004312 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Chrysomya bezziana; Calliphoridae; Abundance; Oviposition; Bait; Traps; Climatic conditions DO - http://dx.doi.org/10.1079/BER2004312 ER - TY - JOUR T1 - Advancing community acceptance of reclaimed water AN - 18027801; 6020669 AB - This paper reports on research into the public acceptance of water reuse, that is, water sourced from highly treated sewage effluent. It distills Bruvold's (1972-1988) USA findings and compares these to an audit of twenty-two recent surveys, with some reference to case studies at eight sites, where potable reuse has been proposed, and four residential reuse sites. It highlights several factors that may help explain a degree of support for potable reuse and confirms relatively high acceptance of non potable reuse. Several areas need further investigation and other known results suggest ways that responsible agencies can promote community trust in the development and management of alternative water resources. JF - Water (Australia) AU - Marks, J S AD - Department of Sociology at The Flinders University of South Australia, GPO Box 2100, Adelaide 2001, Australia, June.Marks@flinders.edu.au Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 46 EP - 51 VL - 31 IS - 5 SN - 0310-0367, 0310-0367 KW - Aqualine Abstracts KW - Water Reuse KW - Reclaimed Water KW - Surveys KW - Water Conservation KW - Water Resources Management KW - Public Opinion KW - AQ 00001:Water Resources and Supplies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18027801?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+%28Australia%29&rft.atitle=Advancing+community+acceptance+of+reclaimed+water&rft.au=Marks%2C+J+S&rft.aulast=Marks&rft.aufirst=J&rft.date=2004-08-01&rft.volume=31&rft.issue=5&rft.spage=46&rft.isbn=&rft.btitle=&rft.title=Water+%28Australia%29&rft.issn=03100367&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Water Reuse; Reclaimed Water; Surveys; Water Conservation; Water Resources Management; Public Opinion ER - TY - JOUR T1 - Biological characterization of Aeromonas spp. isolated from the environment AN - 17886299; 6204030 AB - Cytotoxic enterotoxin (Act) is a key virulence factor in the pathogenesis of infections caused by Aeromonas spp. The cytotoxic enterotoxin gene (act) was detected in 32 out of 69 environmental isolates of Aeromonas spp. by hybridization with the act gene probe. To evaluate the pathogenic potential of the act gene probe-positive isolates, 32 act gene probe-positive and 31 randomly selected act gene probe-negative isolates were tested for enterotoxicity in a suckling mice assay (SMA), for haemolytic activity on sheep blood agar plates, for the presence of CAMP-like factors, and for cytotoxicity in a Vero cell line. The act gene probe-positive isolates significantly differed from the toxin gene probe-negative ones with respect to enterotoxicity in the SMA (P=0 times 009) and haemolytic activity (P=0 times 005). The CAMP-haemolysin phenotype was significantly associated with the rabbit ileal loop assay (P=0 times 08), Vero cell assay (P=0 times 064), and haemolysin production under the microaerophilic conditions (P=0 times 056) of the act gene probe-positive isolates of Aeromonas spp. These data indicated the role of Act in the pathogenesis of Aeromonas infections and that the enterotoxic potential of Aeromonas spp. could be assessed by simply performing a CAMP-haemolysin assay. JF - Epidemiology and Infection AU - Rahim, Z AU - Khan, SI AU - Chopra, A K AD - International Centre for Diarrhoeal Disease Research, Bangladesh: Center for Health and Population Research; GPO Box 128, Dhaka 1000, Bangladesh Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 627 EP - 636 VL - 132 IS - 4 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Blood KW - Agar KW - Cytotoxicity KW - Aeromonas KW - Vero cells KW - virulence factors KW - DNA probes KW - Enterotoxins KW - Infection KW - ACT gene KW - J 02855:Human Bacteriology: Others UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17886299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Biological+characterization+of+Aeromonas+spp.+isolated+from+the+environment&rft.au=Rahim%2C+Z%3BKhan%2C+SI%3BChopra%2C+A+K&rft.aulast=Rahim&rft.aufirst=Z&rft.date=2004-08-01&rft.volume=132&rft.issue=4&rft.spage=627&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268804002298 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Agar; Blood; Cytotoxicity; virulence factors; Vero cells; DNA probes; Enterotoxins; Infection; ACT gene; Aeromonas DO - http://dx.doi.org/10.1017/S0950268804002298 ER - TY - JOUR T1 - An outbreak due to peanuts in their shell caused by Salmonella enterica serotypes Stanley and Newport - sharing molecular information to solve international outbreaks AN - 17880465; 6204024 AB - Salmonellosis is a global problem caused by the international movement of foods and high incidence in exporting countries. In September 2001, in an outbreak investigation Australia isolated Salmonella Stanley from imported peanuts, which resulted in a wider investigation in Canada, England & Wales and Scotland. Patients infected with Salmonella serotypes known to be isolated from peanuts and reported to surveillance systems were interviewed to determine exposure histories. Tagged image file format (TIFF) images of pulsed-field gel electrophoresis (PFGE) patterns of Salmonella isolates were shared electronically amongst laboratories. Laboratories tested packets of `Brand X' peanuts from various lots and product lines. In total, 97 cases of S. Stanley and 12 cases of S. Newport infection were found. Seventy-three per cent (71/97) of S. Stanley cases were in persons of Asian ethnicity. Twenty-eight per cent of cases recalled eating Brand X peanuts and a further 13% had peanuts in their house in the previous month or had eaten Asian-style peanuts. Laboratories isolated S. Stanley, S. Newport, S. Kottbus, S. Lexington and S. Unnamed from Brand X peanuts. Isolates of S. Stanley from peanuts and human patients were indistinguishable by PFGE. This international outbreak resulted from a product originating from one country affecting several others. Rapid sharing of electronic DNA images was a crucial factor in delineating the outbreak; multinational investigations would benefit from a harmonized approach. JF - Epidemiology and Infection AU - Kirk, MD AU - Little, CL AU - Lem, M AU - Fyfe, M AU - Genobile, D AU - Tan, A AU - Threlfall, J AU - Paccagnella, A AU - Lightfoot, D AU - Lyi, H AU - McIntyre, L AU - Ward, L AU - Brown, D J AU - Surnam, S AU - Fisher, IST AD - OzFoodNet, Department of Health and Ageing, Food Safety & Surveillance Section, MDP 15, GPO Box 9848, Canberra City, Australian Capital Territory 2601, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 571 EP - 577 VL - 132 IS - 4 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Houses KW - Serotypes KW - Salmonella enterica KW - Salmonellosis KW - Pulsed-field gel electrophoresis KW - DNA KW - Nuts KW - Shells KW - Infection KW - Food-borne diseases KW - J 02710:Identification, taxonomy and typing KW - J 02846:Gastrointestinal tract UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880465?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=An+outbreak+due+to+peanuts+in+their+shell+caused+by+Salmonella+enterica+serotypes+Stanley+and+Newport+-+sharing+molecular+information+to+solve+international+outbreaks&rft.au=Kirk%2C+MD%3BLittle%2C+CL%3BLem%2C+M%3BFyfe%2C+M%3BGenobile%2C+D%3BTan%2C+A%3BThrelfall%2C+J%3BPaccagnella%2C+A%3BLightfoot%2C+D%3BLyi%2C+H%3BMcIntyre%2C+L%3BWard%2C+L%3BBrown%2C+D+J%3BSurnam%2C+S%3BFisher%2C+IST&rft.aulast=Kirk&rft.aufirst=MD&rft.date=2004-08-01&rft.volume=132&rft.issue=4&rft.spage=571&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026880400216X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Houses; Serotypes; Salmonellosis; DNA; Pulsed-field gel electrophoresis; Nuts; Shells; Infection; Food-borne diseases; Salmonella enterica DO - http://dx.doi.org/10.1017/S095026880400216X ER - TY - JOUR T1 - Gene technology for grain legumes: can it contribute to the food challenge in developing countries? AN - 17880073; 5923728 AB - Grain legumes play a crucial role in the sustainability of agricultural systems and in food protein supply in developing countries. Several constraints that limit crop production or quality have been addressed by conventional breeding and enhanced management, but there are situations where the existing germplasm lacks the required traits. Genetic transformation could help provide solutions to certain constraints, thus improving food security in developing countries. The potential benefits of this form of genetic improvement have not yet been realised, mainly because efficient and reproducible gene transfer systems are not available. We review the state of the art of gene technology for genetic improvement of those grain legumes of major importance to developing countries. Protocols are evaluated for their reproducibility, efficiency and robustness. JF - Plant Science AU - Popelka, J C AU - Terryn, N AU - Higgins, TJV AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, carlos.popelka@csiro.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 195 EP - 206 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 167 IS - 2 SN - 0168-9452, 0168-9452 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - Transformation KW - Food KW - Plant breeding KW - Crop production KW - Gene transfer KW - Reviews KW - Legumes KW - Germplasm KW - Grain KW - Developing countries KW - W2 32065:Plants KW - W2 32440:Plant breeding KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Science&rft.atitle=Gene+technology+for+grain+legumes%3A+can+it+contribute+to+the+food+challenge+in+developing+countries%3F&rft.au=Popelka%2C+J+C%3BTerryn%2C+N%3BHiggins%2C+TJV&rft.aulast=Popelka&rft.aufirst=J&rft.date=2004-08-01&rft.volume=167&rft.issue=2&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Plant+Science&rft.issn=01689452&rft_id=info:doi/10.1016%2Fj.plantsci.2004.03.027 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Developing countries; Legumes; Grain; Food; Crop production; Germplasm; Plant breeding; Reviews; Transformation; Gene transfer DO - http://dx.doi.org/10.1016/j.plantsci.2004.03.027 ER - TY - JOUR T1 - Infant handling and mortality in yellow baboons (Papio cynocephalus): evidence for female reproductive competition? AN - 17715685; 6018567 AB - This study examines negative and positive infant handling behavior in 24 free-ranging yellow baboon infants (Papio cynocephalus) studied over a 5-year period in Mikumi National Park, Tanzania. We test predictions of the female reproductive competition hypothesis to explain patterns of infant handling behavior by adult females (excluding the infant's mother) in relation to observed cases of infant mortality by age 3 months (25% of infants in this study). Results show that: (1) low-ranking infants received more negative infant handling than high-ranking infants; conversely high-ranking infants received more positive infant handling; (2) female kin engaged in higher levels of positive infant handling than did non-kin, whereas non-kin showed higher levels of negative infant handling; (3) rates of negative infant handling varied by season, with high levels at the onset of the rainy season; and (4) high level of negative infant handling was a significant predictor of infant mortality by age 3 months (infant rank and sex did not predict survival). We discuss how the occurrence and interpretation of infant handling behavior in the literature has likely been confused by different definitions of this behavior, as well as differences in the socio-ecological context in which this behavior occurs. JF - Behavioral Ecology and Sociobiology AU - Kleindorfer, S AU - Wasser, S K AD - School of Biological Sciences, Flinders University of South Australia, GPO Box 2100, 5001, Adelaide, Australia, sonia.kleindorfer@flinders.edu.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 328 EP - 337 PB - Springer-Verlag VL - 56 IS - 4 SN - 0340-5443, 0340-5443 KW - Yellow Baboon KW - Animal Behavior Abstracts; Ecology Abstracts KW - Mortality KW - Parent-offspring interactions KW - Reproduction KW - Papio cynocephalus KW - Competition KW - Y 25448:Primates KW - D 04672:Mammals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17715685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Behavioral+Ecology+and+Sociobiology&rft.atitle=Infant+handling+and+mortality+in+yellow+baboons+%28Papio+cynocephalus%29%3A+evidence+for+female+reproductive+competition%3F&rft.au=Kleindorfer%2C+S%3BWasser%2C+S+K&rft.aulast=Kleindorfer&rft.aufirst=S&rft.date=2004-08-01&rft.volume=56&rft.issue=4&rft.spage=328&rft.isbn=&rft.btitle=&rft.title=Behavioral+Ecology+and+Sociobiology&rft.issn=03405443&rft_id=info:doi/10.1007%2Fs00265-004-0798-1 L2 - http://link.springer.de/link/service/journals/00265/bibs/4056004/40560328.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Papio cynocephalus; Mortality; Reproduction; Competition; Parent-offspring interactions DO - http://dx.doi.org/10.1007/s00265-004-0798-1 ER - TY - JOUR T1 - Effect of Oxygen Tension on Adult Articular Chondrocytes in Microcarrier Bioreactor Culture AN - 17710229; 6072196 AB - Tissue-engineering approaches for cartilage repair hold promise for the treatment of cartilage defects. Various methods to prevent or reduce dedifferentiation during chondrocyte expansion are currently under investigation. In the present study we evaluated the effect of oxygen on chondrocyte proliferation, as oxygen has received increased attention as a possible regulator of chondrocyte differentiation and its effect during expansion is uncertain. Therefore, the effect of three oxygen tensions (4, 10.5, and 21%) was investigated in a bioreactor microcarrier culture, which allows precise control of the oxygen tension in the liquid phase. During culture cells acquired a round shape on microcarriers. No differences in proliferation rate of chondrocytes were observed within the range of oxygen tensions evaluated. Cells exhibited predominantly anaerobic metabolism and, per mole of glucose, approximately 2 mol of lactate was produced independent of oxygen tension. Cellular oxygen consumption was comparable for all bioreactor cultures. Nevertheless, specific consumption rates were relatively high (2-4 X 10 super(-17) mol times cell super(-1) times s super(-1)), in comparison with chondrocytes in cartilage (0.8-2.2 X 10 super(-18) mol times cell super(-1)). Subsequent cartilaginous tissue formation in pellets was not affected as qualitatively assessed by safranin-O staining. At the oxygen concentrations evaluated, no effect of oxygen tension was observed on proliferation, oxygen consumption, and yield of lactate on glucose administration. For future investigations of chondrocytes and oxygen, the bioreactor system, which allows precise control and monitoring of oxygen tension, holds promise. JF - Tissue Engineering AU - Malda, J AU - Van Den Brink, P AU - Meeuwse, P AU - Grojec, M AU - Martens, DE AU - Tramper, J AU - Riesle, J AU - Van Blitterswijk, CA AD - Institute of Health and Biomedical Innovation, School of Life Sciences, Queensland University of Technology, GPO Box 2939, Brisbane Qld 4001, Australia, jos@malda.nl Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 987 EP - 994 VL - 10 IS - 7-8 SN - 1076-3279, 1076-3279 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Oxygen tension KW - Cartilage KW - Glucose KW - Chondrocytes KW - Cell culture KW - Bioreactors KW - safranin-O KW - Oxygen consumption KW - Tissue engineering KW - Oxygen KW - Lactic acid KW - Chondrogenesis KW - W 30965:Miscellaneous, Reviews KW - W3 33220:Cell culture KW - W4 110:Biomedical Materials & Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17710229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tissue+Engineering&rft.atitle=Effect+of+Oxygen+Tension+on+Adult+Articular+Chondrocytes+in+Microcarrier+Bioreactor+Culture&rft.au=Malda%2C+J%3BVan+Den+Brink%2C+P%3BMeeuwse%2C+P%3BGrojec%2C+M%3BMartens%2C+DE%3BTramper%2C+J%3BRiesle%2C+J%3BVan+Blitterswijk%2C+CA&rft.aulast=Malda&rft.aufirst=J&rft.date=2004-08-01&rft.volume=10&rft.issue=7-8&rft.spage=987&rft.isbn=&rft.btitle=&rft.title=Tissue+Engineering&rft.issn=10763279&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Oxygen tension; Chondrocytes; Oxygen; Bioreactors; Cell culture; Cartilage; Glucose; Oxygen consumption; Lactic acid; Tissue engineering; Chondrogenesis; safranin-O ER - TY - JOUR T1 - Ultra-high-resolution seasonality of trace-ion species and oxygen isotope ratios in Antarctic firn over four annual cycles AN - 17391753; 6491288 AB - Ultra-high-resolution firn-core records covering four annual cycles of oxygen isotope ratios ( delta super(18)O) and trace-ion species were generated from a high-accumulation site on Law Dome, East Antarctica. Event-scale dating of the records was established using hourly snow accumulation measurements from a co-located automatic weather station (AWS). These net accumulation events were used to examine the seasonal timing of delta super(18)O and a suite of trace-ion species including marine biogenic sulphur compounds (methanesulphonic acid (MSA), non-sea salt sulphate), nitrate and major sea-salt species (sodium, chloride, magnesium). The ultra-high-resolution nature of this study and independent dating scale provide an opportunity to examine exact timings in the seasonality of each species. The traditional summer-maximum species of delta super(18)O and MSA show consistent relative phasing during mid-summer over the four annual cycles. Nitrate shows an erratic seasonal cycle with a general trend characterized by narrow peaks during spring and early summer, preceding the mid-summer peaks in delta super(18)O and MSA. Non-sea-salt sulphate cycles indicate similar characteristics to MSA signals during summer, but are more comparable to nitrate signals during spring, autumn and winter. This suggests the summer non-sea-salt sulphate signal is driven by biological activity, although this species appears to be linked with nitrate signals outside the summer season. Finally, the sea-salt species indicate a seasonal cycle characterized by maximum concentrations during spring, winter and autumn. Event-scale dating of the firn-core records allows direct comparisons between the seasonal cycles and meteorological conditions. Contemporaneous local air-temperature measurements are compared with the high-resolution delta super(18)O record. This allows a detailed investigation of the relationship between site temperature and delta super(18)O signals in the ice core. JF - Annals of Glaciology AU - McMorrow, A AU - van Ommen, TD AU - Morgan, V AU - Curran AD - Technology Futures Team, Australian Greenhouse Office, Department of the Environment and Heritage, John Gorton Building, GPO Box 787, Canberra, ACT 2601, Australia, Alison.McMorrow@deh.gov.au A2 - Jacka, TH (ed) Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 34 EP - 40 PB - International Glaciological Society, Lensfield Road Cambridge CB2 1ER UK VL - 39 SN - 0260-3055, 0260-3055 KW - Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts KW - Sulfates KW - Timing KW - Nitrates KW - Temperature KW - Snow accumulation KW - Antarctic conferences KW - Antarctic glaciology KW - Oxygen isotopes KW - Glacier symposia KW - Sulfur compounds in seawater KW - Dating KW - Antarctica, Wilkes Land, Budd Coast, Law Dome KW - Oxygen Isotopes KW - Seasonal variability KW - Accumulation KW - Automatic weather stations KW - Meteorological conditions KW - Firn KW - SW 0880:Chemical processes KW - M2 551.321:General Methods/Instruments (551.321) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17391753?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Annals+of+Glaciology&rft.atitle=Ultra-high-resolution+seasonality+of+trace-ion+species+and+oxygen+isotope+ratios+in+Antarctic+firn+over+four+annual+cycles&rft.au=McMorrow%2C+A%3Bvan+Ommen%2C+TD%3BMorgan%2C+V%3BCurran&rft.aulast=McMorrow&rft.aufirst=A&rft.date=2004-08-01&rft.volume=39&rft.issue=&rft.spage=34&rft.isbn=&rft.btitle=&rft.title=Annals+of+Glaciology&rft.issn=02603055&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-06-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Oxygen isotopes; Sulfur compounds in seawater; Glacier symposia; Snow accumulation; Seasonal variability; Meteorological conditions; Antarctic conferences; Automatic weather stations; Antarctic glaciology; Timing; Sulfates; Nitrates; Dating; Temperature; Oxygen Isotopes; Accumulation; Firn; Antarctica, Wilkes Land, Budd Coast, Law Dome ER - TY - JOUR T1 - Pediatric mortality in Africa: Plasmodium falciparum malaria as a cause or risk? AN - 17306398; 6068599 AB - The disability adjusted life year (DALY) approach of defining cause-specific health burdens is becoming the benchmark for international disease control prioritization. For malaria, this categorical approach may not fully capture its burden that includes chronic anemia, low birth weight, and enhancement of the severity of other childhood diseases. We investigated the extent to which malaria acts as a risk factor for all-cause mortality in African children less than five years of age from 1) ecologic associations between Plasmodium falciparum infection prevalence (PR) and under-five mortality, and 2) reductions in all-cause under-five mortality achieved in malaria intervention trials. Across 48 demographic surveillance studies, when adjusted for secular trends, PR more than doubled all-cause mortality (P = 0.0001). Trials of insecticide-treated mosquito nets generally found smaller population-attributable fractions of pediatric mortality to malaria infection, which may relate to their imperfect coverage and efficacy. In conclusion, the disability and death burden due to malaria in African children could be higher than that detectable from cause-specific DALY estimations. JF - American Journal of Tropical Medicine and Hygiene AU - Snow, R W AU - Korenromp, EL AU - Gouws, E AD - Kenya Medical Research Institute-Wellcome Trust Collaborative Program, 00100 GPO, PO Box 43640, Nairobi, Kenya, rsnow@wtnairobi.mimcom.net Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 16 EP - 24 VL - 71 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Risk Abstracts KW - K 03090:Protozoa: human KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17306398?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Pediatric+mortality+in+Africa%3A+Plasmodium+falciparum+malaria+as+a+cause+or+risk%3F&rft.au=Snow%2C+R+W%3BKorenromp%2C+EL%3BGouws%2C+E&rft.aulast=Snow&rft.aufirst=R&rft.date=2004-08-01&rft.volume=71&rft.issue=2&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-10-01 N1 - SuppNotes - Special Issue: Malaria in Africa. N1 - Last updated - 2011-12-13 ER - TY - CONF T1 - Invaders in the north -- an appraisal of Queensland's (Australia) strategic approach to pest fish management AN - 17298989; 6111223 AB - Invasive fish species have long been considered a problem in Queensland, Australia with 17 species forming self-sustaining populations in Queensland waters. The Queensland Fisheries Service (QFS) established a project in 1999 to develop a strategy for controlling these fish. "Controlling exotic pest fishes--an operational strategy for Queensland Freshwaters 2000-2005" (the strategy) was released in early 2001 and has been progressively implemented since that time. QFS have worked very closely with the community and industry in the management of invasive species and the pest fish project has had some notable successes. These include a well-recognised state-wide education programme and the installation of multi-million dollar screens on impoundments to prevent inter-basin transfer. In recognition of the increasing rate of fish smuggling into Queensland, a process has been developed to amend the current legislation to ensure that it is enforceable, accepted by the community and industry, and scientifically valid. This workshop will explore the reasons for these successes and some of the challenges encountered whilst implementing the strategy. The future policy direction of the pest fish programme will also be discussed as QFS intends to manage pest fish within a wider habitat management framework. This holistic approach to habitat management will incorporate many of the approaches to community engagement and education developed during the pest fish project. JF - S I R Publishing, P.O. Box 399 Wellington New Zealand. p. 566. Aug 2004. AU - Mackenzie, R Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 566 PB - S I R Publishing, P.O. Box 399 Wellington New Zealand, [URL:http://www.rsnz.govt.nz/] VL - 38 IS - 3 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Freshwater KW - Q5 01521:Mechanical and natural changes KW - Q1 01485:Species interactions: pests and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17298989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=Invaders+in+the+north+--+an+appraisal+of+Queensland%27s+%28Australia%29+strategic+approach+to+pest+fish+management&rft.au=Mackenzie%2C+R&rft.aulast=Mackenzie&rft.aufirst=R&rft.date=2004-08-01&rft.volume=38&rft.issue=3&rft.spage=566&rft.isbn=&rft.btitle=&rft.title=&rft.issn=00288330&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - SuppNotes - Special Issue: invasive species N1 - Last updated - 2011-12-13 ER - TY - CONF T1 - Eradication of exotic pest fish -- present and future options AN - 17298945; 6111216 AB - A wide range of techniques have been proposed to manage, if not actually eradicate invasive fish species. A number have been tried (e.g., physical removal, biocides), usually with limited success, others are currently being attempted (e.g., sterile male releases), and still more are under development (e.g., genetic technologies). These techniques and attempts will be reviewed briefly, the strengths and weaknesses of each will be discussed, and their potential for pest eradication evaluated in a general framework that looks at both the likelihood they will achieve eradication, or at least substantial and sustained reduction of pest impacts, and the likelihood the public will ever let them be used. JF - S I R Publishing, P.O. Box 399 Wellington New Zealand. p. 564. Aug 2004. AU - Thresher, R Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 564 PB - S I R Publishing, P.O. Box 399 Wellington New Zealand, [URL:http://www.rsnz.govt.nz/] VL - 38 IS - 3 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Marine KW - Q5 01522:Protective measures and control KW - O 4090:Conservation and Environmental Protection KW - Q1 01485:Species interactions: pests and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17298945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=Eradication+of+exotic+pest+fish+--+present+and+future+options&rft.au=Thresher%2C+R&rft.aulast=Thresher&rft.aufirst=R&rft.date=2004-08-01&rft.volume=38&rft.issue=3&rft.spage=564&rft.isbn=&rft.btitle=&rft.title=&rft.issn=00288330&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - SuppNotes - Special Issue: invasive species N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Wastewater treatment effectiveness: A review AN - 16179332; 6020675 AB - A review of the literature was undertaken to determine the ranges of pathogen removal by the unit processes commonly used in the treatment of wastewater prior to disinfection. It was found that the order of effectiveness ranged from primary sedimentation, followed by trickling filter, physicochemical treatment with alum/polymer, rapid sand filtration, activated sludge, physicochemical treatment with lime, dissolved air flotation, slow sand filtration, lagoons (with sufficient HRT) and membrane processes. JF - Water (Australia) AU - Parkinson, A AU - Roddick, F A AD - School of Civil and Chemical Engineering, RMIT University, GPO Box 2476V, Melbourne, Victoria, 3001, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 63 EP - 68 VL - 31 IS - 5 SN - 0310-0367, 0310-0367 KW - Aqualine Abstracts KW - Disinfection KW - Performance Evaluation KW - Membranes KW - Physicochemical Treatment KW - Sand Filters KW - Trickling Filters KW - Literature Review KW - Sedimentation KW - Wastewater Treatment KW - Flotation KW - Lagoons KW - AQ 00006:Sewage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16179332?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+%28Australia%29&rft.atitle=Wastewater+treatment+effectiveness%3A+A+review&rft.au=Parkinson%2C+A%3BRoddick%2C+F+A&rft.aulast=Parkinson&rft.aufirst=A&rft.date=2004-08-01&rft.volume=31&rft.issue=5&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=Water+%28Australia%29&rft.issn=03100367&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2004-10-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Disinfection; Performance Evaluation; Membranes; Physicochemical Treatment; Sand Filters; Trickling Filters; Sedimentation; Literature Review; Lagoons; Flotation; Wastewater Treatment ER - TY - JOUR T1 - Drinking Water Contaminants, Gene Polymorphisms, and Fetal Growth AN - 14709139; 10667558 JF - Environmental Health Perspectives AU - Infante-Rivard, Claire Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1213 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHLOROFORM KW - QUEBEC PROVINCE KW - TRIHALOMETHANE KW - RISK ASSESSMENT KW - REPRODUCTION, HUMAN KW - WATER, DRINKING KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709139?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Drinking+Water+Contaminants%2C+Gene+Polymorphisms%2C+and+Fetal+Growth&rft.au=Infante-Rivard%2C+Claire&rft.aulast=Infante-Rivard&rft.aufirst=Claire&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1213&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; CHLOROFORM; REPRODUCTION, HUMAN; QUEBEC PROVINCE; WATER, DRINKING; GENETICS, HUMAN; TRIHALOMETHANE ER - TY - JOUR T1 - Pesticide Spraying for West Nile Virus Control and Emergency Department Asthma Visits in New York City, 2000 AN - 14708012; 10667552 AB - During the 2000 West Nile Virus season, New York City used a pyrethroid pesticide exclusively. A time-series analysis across ZIP codes in the city was conducted to determine whether truck-based ground spraying precipitated an increase in asthma exacerbations requiring emergency department treatment. Only data from the 11 public hospital emergency departments were used. Results showed that the pesticide application schedule coincided with both the summer trough and the subsequent autumn increase in asthma visits. Multivariate analysis revealed no significant association between neighborhood spraying and subsequent rates of emergency department visits for asthma. JF - Environmental Health Perspectives AU - Karpati, Adam M AU - Perrin, Mary C AU - Matte, Tom AU - Leighton, Jessica AU - Schwartz, Joel AU - Barr, RGraham Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1183 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PYRETHROID PESTICIDES KW - HEALTH FACILITIES KW - INSECTICIDE APPLICATION KW - ASTHMA KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pesticide+Spraying+for+West+Nile+Virus+Control+and+Emergency+Department+Asthma+Visits+in+New+York+City%2C+2000&rft.au=Karpati%2C+Adam+M%3BPerrin%2C+Mary+C%3BMatte%2C+Tom%3BLeighton%2C+Jessica%3BSchwartz%2C+Joel%3BBarr%2C+RGraham&rft.aulast=Karpati&rft.aufirst=Adam&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1183&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH FACILITIES; PYRETHROID PESTICIDES; INSECTICIDE APPLICATION; ASTHMA; NEW YORK CITY ER - TY - JOUR T1 - Behavioral Alterations in Response to Fear-Provoking Stimuli and Tranylcypromine Induced by Perinatal Exposure to Bisphenol A and Nonylphenol in Male Rats AN - 14707983; 10667548 AB - The adverse effects of a low-dose perinatal bisphenol A or nonylphenol exposure on the behavioral characteristics of male rats were investigated. The tests included an open-field test, spontaneous activity during a dark phase, a step-through passive avoidance test, an elevated plus-maze test, and a two-way shuttle-box avoidance test. In addition, behavioral responses to tranylcypromine (Tcy), a monoamine oxidase inhibitor, were also considered. Dams were dosed orally with bisphenol A at a dose of 0.1 mg/kg/d or with nitrophenol at doses of 0.1 or 10.0 mg/kg/d from gestational day 3 until postnatal day 20. One male pup per litter was selected randomly for behavioral testing. Results showed that behavioral alterations by perinatal exposure to the compounds were observed only in specific challenges involving fear-provoking stimuli and pharmacologic disruption of the monoaminergic system. In the passive avoidance test, offspring perinatally exposed to bisphenol A or nitrophenol appeared to be more sensitive to fear-inducing shock than were control offspring, and in the active avoidance test, bisphenol A and low-dose nonylphenol showed clear or partial adverse effects on behavior, respectively. In the monoamine-disruption test, Tcy-induced increases in locomotion were significantly less marked in the bisphenol A-treated and low-dose nonylphenol-treated offspring, but not in the high-dose nonylphenol-treated offspring, compared to controls. JF - Environmental Health Perspectives AU - Negishi, Takayuki AU - Kawasaki, Katsuyoshi AU - Suzaki, Shingo AU - Maeda, Haruna AU - Ishii, Yoshiyuki AU - Kyuwa, Shigeru AU - Kuroda, Yoichiro Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1159 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BEHAVIOR KW - PHYSIOLOGICAL EFFECTS KW - REPRODUCTION, ANIMAL KW - RATS KW - HORMONES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Behavioral+Alterations+in+Response+to+Fear-Provoking+Stimuli+and+Tranylcypromine+Induced+by+Perinatal+Exposure+to+Bisphenol+A+and+Nonylphenol+in+Male+Rats&rft.au=Negishi%2C+Takayuki%3BKawasaki%2C+Katsuyoshi%3BSuzaki%2C+Shingo%3BMaeda%2C+Haruna%3BIshii%2C+Yoshiyuki%3BKyuwa%2C+Shigeru%3BKuroda%2C+Yoichiro&rft.aulast=Negishi&rft.aufirst=Takayuki&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1159&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 11 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PHYSIOLOGICAL EFFECTS; BEHAVIOR; REPRODUCTION, ANIMAL; RATS; HORMONES ER - TY - JOUR T1 - Perfluorooctane Sulfonate (PFOS) and Related Perfluorinated Compounds in Human Maternal and Cord Blood Samples: Assessment of PFOS Exposure in a Susceptible Population During Pregnancy AN - 14707910; 10667556 AB - Cord blood and maternal serum samples were collected from a group of pregnant women recruited at Sapporo Toho Hospitals in Hokkaido, Japan, and the samples were analyzed for concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorooctane sulfonylamide (PFOSA), which are stable chemicals with a wide range of industrial and consumer applications. The analytical procedures used are described. In the 15 blood pairs analyzed, PFOS concentrations in maternal serum samples ranged 4.917.6 ng/ml, while those in cord blood ranged 1.65.3 ng/ml, and the levels in the two matrices were correlated highly. Only a small number of maternal samples had detectable PFOA, whereas no cord blood samples did, which was also found for PFOSA. JF - Environmental Health Perspectives AU - Inoue, Koichi AU - Okada, Fumio AU - Ito, Rie AU - Kato, Shizue AU - Sasaki, Seiko AU - Nakajima, Sonomi AU - Uno, Akiko Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1204 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - ORGANIC COMPOUNDS KW - REPRODUCTION, HUMAN KW - JAPAN KW - FLUORINE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707910?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Perfluorooctane+Sulfonate+%28PFOS%29+and+Related+Perfluorinated+Compounds+in+Human+Maternal+and+Cord+Blood+Samples%3A+Assessment+of+PFOS+Exposure+in+a+Susceptible+Population+During+Pregnancy&rft.au=Inoue%2C+Koichi%3BOkada%2C+Fumio%3BIto%2C+Rie%3BKato%2C+Shizue%3BSasaki%2C+Seiko%3BNakajima%2C+Sonomi%3BUno%2C+Akiko&rft.aulast=Inoue&rft.aufirst=Koichi&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1204&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; ORGANIC COMPOUNDS; JAPAN; REPRODUCTION, HUMAN; FLUORINE ER - TY - JOUR T1 - Discriminating Different Classes of Toxicants by Transcript Profiling AN - 14707831; 10667800 AB - Results from animal studies involving 28 well-known hepatotoxicants and three nonhepatotoxic compounds were used to discriminate different classes of toxicants by transcript profiling. Recursive feature elimination was used to create sets of informative genes, and all support vector machine classifications were based on the software package, LIBSVM. Results revealed that classification problems in toxicogenomics could be addressed effectively by the supervised learning approach. By combining support vector machine parameter optimization with a compound-based external cross-validation scheme and recursive feature elimination, accurate classification of the compounds included in the training set was achieved. JF - Environmental Health Perspectives AU - Steiner, Guido AU - Suter, Laura AU - Boess, Franziska AU - Gasser, Rodolfo AU - de Vera, Maria Cristina AU - Albertini, Silvio AU - Ruepp, Stefan Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1236 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707831?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Discriminating+Different+Classes+of+Toxicants+by+Transcript+Profiling&rft.au=Steiner%2C+Guido%3BSuter%2C+Laura%3BBoess%2C+Franziska%3BGasser%2C+Rodolfo%3Bde+Vera%2C+Maria+Cristina%3BAlbertini%2C+Silvio%3BRuepp%2C+Stefan&rft.aulast=Steiner&rft.aufirst=Guido&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1236&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; HEPATOTOXICITY ER - TY - JOUR T1 - Fetal Exposure to PCBs and Their Hydroxylated Metabolites in a Dutch Cohort AN - 14707815; 10667557 AB - Levels of PCBs and hydroxylated PCBs (OH-PCBs) were measured in mothers and children at birth in a cohort recruited in the Netherlands. In total, 51 paired maternal and cord blood plasma samples were analyzed. The sum PCBs in maternal plasma ranged 113619 ng/g lipid, and those in cord blood ranged 78809 ng/g lipid, while the respective sum OH-PCBs ranged 14125 and 49244 ng/g lipid. With the exception of PCB congeners 118 and 156, there was a significant correlation between the maternal and cord plasma levels, indicating transfer across the placental barrier. JF - Environmental Health Perspectives AU - Soechitram, Shalini Devi AU - Athanasiadou, Maria AU - Hovander, Lotta AU - Bergman, Ake AU - Sauer, Pieter Jan Jacob Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1208 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - POLYCHLORINATED BIPHENYLS KW - METABOLIC ACTIVATION KW - REPRODUCTION, HUMAN KW - NETHERLANDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707815?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Fetal+Exposure+to+PCBs+and+Their+Hydroxylated+Metabolites+in+a+Dutch+Cohort&rft.au=Soechitram%2C+Shalini+Devi%3BAthanasiadou%2C+Maria%3BHovander%2C+Lotta%3BBergman%2C+Ake%3BSauer%2C+Pieter+Jan+Jacob&rft.aulast=Soechitram&rft.aufirst=Shalini&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1208&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; METABOLIC ACTIVATION; NETHERLANDS; REPRODUCTION, HUMAN ER - TY - JOUR T1 - Hair Mercury Levels in U.S. Children and Women of Childbearing Age: Reference Range Data from NHANES 19992000 AN - 14707785; 10667549 AB - The National Health and Nutrition Examination Survey (NHANES) mercury assessment component targeted children 15 yr of age and women 1649 yr of age, and the assessment conducted in 19992000 included a dietary interview and blood, hair, and urinary Hg assessments. Survey results are presented for hair Hg levels in relation to race/ethnicity, fish consumption frequency level, pregnancy status, and education level. Among children, the geometric mean total hair Hg concentration was 0.12 mu g/g, and non-Hispanic black and Mexican-American children had higher levels than non-Hispanic white children, and boys and higher levels than girls. Hair Hg levels increased with increasing frequency of fish consumption for both children and adults. Hair Hg levels of pregnant women did not differ from those of nonpregnant women. Weighted Pearson correlations between log blood and log hair Hg were 0.67 and 0.79 for children and women, respectively. JF - Environmental Health Perspectives AU - McDowell, Margaret A AU - Dillon, Charles F AU - Osterloh, John AU - Bolger, PMichael AU - Pellizzari, Edo AU - Fernando, Reshan AU - Montes de Oca, Ruben Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1165 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PREGNANCY KW - DIET KW - AGE COMPARISONS KW - HAIR KW - BLOOD ANALYSIS KW - NATIONALITY COMPARISONS KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Hair+Mercury+Levels+in+U.S.+Children+and+Women+of+Childbearing+Age%3A+Reference+Range+Data+from+NHANES+1999%26lt%3BND%26gt%3B2000&rft.au=McDowell%2C+Margaret+A%3BDillon%2C+Charles+F%3BOsterloh%2C+John%3BBolger%2C+PMichael%3BPellizzari%2C+Edo%3BFernando%2C+Reshan%3BMontes+de+Oca%2C+Ruben&rft.aulast=McDowell&rft.aufirst=Margaret&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1165&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; PREGNANCY; DIET; NATIONALITY COMPARISONS; AGE COMPARISONS; MERCURY; HAIR ER - TY - JOUR T1 - The Need to Decide If All Estrogens Are Intrinsically Similar AN - 14707737; 10667544 AB - Genes expressed in the immature mouse uterus when grown in response to treatment with phytoestrogens and synthetic estrogens were compared. The estrogens included 17 beta -estradiol, diethylstilbestrol, and genistein, which constituted a physiologic estrogen, a synthetic estrogen, and a phytoestrogen, respectively. A high degree of similarity was found between the transcriptional responses to each of the three estrogens. While the estrogens were found to alter the expression of some genes with different magnitudes, the data showed that the same genes were affected during equivalent uterotrophic responses. JF - Environmental Health Perspectives AU - Moggs, Jonathan G AU - Ashby, John AU - Tinwell, Helen AU - Lim, Fei Ling AU - Moore, David J AU - Kimber, Ian AU - Orphanides, George Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1137 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PLANTS, BIOLOGIC KW - DIETHYLSTILBESTROL KW - BIOASSAY KW - HORMONES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Need+to+Decide+If+All+Estrogens+Are+Intrinsically+Similar&rft.au=Moggs%2C+Jonathan+G%3BAshby%2C+John%3BTinwell%2C+Helen%3BLim%2C+Fei+Ling%3BMoore%2C+David+J%3BKimber%2C+Ian%3BOrphanides%2C+George&rft.aulast=Moggs&rft.aufirst=Jonathan&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1137&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PLANTS, BIOLOGIC; DIETHYLSTILBESTROL; BIOASSAY; HORMONES ER - TY - JOUR T1 - Valproic Acid Teratogenicity: a Toxicogenomics Approach AN - 14707334; 10667799 AB - Spotted cDNA microarrays were used to monitor global gene expression changes in response to the anti-epileptic drug, valproic acid, which has been shown to induce neural tube defects in human, mouse, and other vertebrate embryos. Altered expressions of multiple genes in mouse embryos after treatment with valproic acid are reported and discussed in light of neural tube development and previously known valproic acid actions. Using the mouse embryo-carcinoma cell line, P19, as an in vitro model of early pluripotent embryonic cells, a subset of valproic acid-responsive genes is identified that may be particularly relevant potential biomarkers of valproic acid teratogenicity. JF - Environmental Health Perspectives AU - Kultima, Kim AU - Nystrom, Anna-Maja AU - Scholz, Birger AU - Gustafson, Anne-Lee AU - Dencker, Lennart AU - Stigson, Michael Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1225 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - TERATOGENIC AGENTS KW - DRUGS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Valproic+Acid+Teratogenicity%3A+a+Toxicogenomics+Approach&rft.au=Kultima%2C+Kim%3BNystrom%2C+Anna-Maja%3BScholz%2C+Birger%3BGustafson%2C+Anne-Lee%3BDencker%2C+Lennart%3BStigson%2C+Michael&rft.aulast=Kultima&rft.aufirst=Kim&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1225&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; TERATOGENIC AGENTS; DRUGS ER - TY - JOUR T1 - The Relationship Between Levels of PCBs and Pesticides in Human Hair and Blood: Preliminary Results AN - 14706927; 10667554 AB - Blood and hair samples were collected from ten Caucasian subjects, and the relationship between PCB and pesticide levels in the two matrices was explored. The hair samples were also washed, and the washing solution was analyzed. The analytical protocol employed is described. Strong correlations were found between hair and blood levels of p,p'-DDE, and the correlation was stronger than that for p,p'-DDT. A moderate hair-to-blood correlation was found for PCB congeners 28, 74, 99, 170, 180, and 194. The percentage of lipids and the levels of organic contaminants in hair were generally higher than those in serum, with levels in hair above the detection limits for all compounds except PCB congener 25 and dieldrin. Washing the hair with shampoo, as opposed to water only, decreased the levels of PCBs, pesticides, and lipids by 2533%, on average, but for less-chlorinated congeners, the decrease was larger. JF - Environmental Health Perspectives AU - Altshul, Larisa AU - Covaci, Adrian AU - Hauser, Russ Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1193 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PESTICIDE RESIDUES KW - BIOLOGICAL INDICATORS KW - BIOACCUMULATION, HUMAN KW - HAIR KW - BLOOD ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+Between+Levels+of+PCBs+and+Pesticides+in+Human+Hair+and+Blood%3A+Preliminary+Results&rft.au=Altshul%2C+Larisa%3BCovaci%2C+Adrian%3BHauser%2C+Russ&rft.aulast=Altshul&rft.aufirst=Larisa&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1193&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; PESTICIDE RESIDUES; BIOLOGICAL INDICATORS; BIOACCUMULATION, HUMAN; HAIR ER - TY - JOUR T1 - The Association Between Environmental Lead Exposure and Bone Density in Children AN - 14706754; 10667555 JF - Environmental Health Perspectives AU - Campbell, James R AU - Rosier, Randy N AU - Novotny, Leonore AU - Puzas, JEdward Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1200 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - BONE GROWTH KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Association+Between+Environmental+Lead+Exposure+and+Bone+Density+in+Children&rft.au=Campbell%2C+James+R%3BRosier%2C+Randy+N%3BNovotny%2C+Leonore%3BPuzas%2C+JEdward&rft.aulast=Campbell&rft.aufirst=James&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1200&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD LEAD LEVEL; BONE GROWTH; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Gene Interaction Network Suggests Dioxin Induces a Significant Linkage Between Aryl Hydrocarbon Receptor and Retinoic Acid Receptor Beta AN - 14706079; 10667798 JF - Environmental Health Perspectives AU - Toyoshiba, Hiroyoshi AU - Yamanaka, Takeharu AU - Sone, Hideko AU - Parham, Frederick M AU - Walker, Nigel J AU - Martinez, Jeanelle AU - Portier, Christopher J Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1217 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MATHEMATIC MODELS, BIOLOGICAL KW - GENETICS, HUMAN KW - TETRACHLORODIBENZODIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Gene+Interaction+Network+Suggests+Dioxin+Induces+a+Significant+Linkage+Between+Aryl+Hydrocarbon+Receptor+and+Retinoic+Acid+Receptor+Beta&rft.au=Toyoshiba%2C+Hiroyoshi%3BYamanaka%2C+Takeharu%3BSone%2C+Hideko%3BParham%2C+Frederick+M%3BWalker%2C+Nigel+J%3BMartinez%2C+Jeanelle%3BPortier%2C+Christopher+J&rft.aulast=Toyoshiba&rft.aufirst=Hiroyoshi&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1217&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MATHEMATIC MODELS, BIOLOGICAL; GENETICS, HUMAN; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Lead, Diabetes, Hypertension, and Renal Function: the Normative Aging Study AN - 14705376; 10667551 AB - Data from subjects included in the Normative Aging Study with no previous known heavy lead exposure were used to examine the effect of low-level bone and blood Pb levels on renal function. The relationships were assessed further by considering the potential modifying effect of diabetes and hypertension. Significant associations of bone Pb with prospective follow-up measures and annual change in serum creatinine were observed among subject with diabetes. The analysis of Pb, hypertension, and serum creatinine indicated that both the association between follow-up blood Pb with follow-up measures of serum creatinine and the association between tibia Pb and prospective annual change in serum creatinine were modified significantly by hypertensive status, with hypertensive subjects having stronger and more significant associations. JF - Environmental Health Perspectives AU - Tsaih, Shirng-Wern AU - Korrick, Susan AU - Schwartz, Joel AU - Amarasiriwardena, Chitra AU - Aro, Antonio AU - Sparrow, David AU - Hu, Howard Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1178 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - NEPHROTOXICITY KW - CARDIOVASCULAR DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705376?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lead%2C+Diabetes%2C+Hypertension%2C+and+Renal+Function%3A+the+Normative+Aging+Study&rft.au=Tsaih%2C+Shirng-Wern%3BKorrick%2C+Susan%3BSchwartz%2C+Joel%3BAmarasiriwardena%2C+Chitra%3BAro%2C+Antonio%3BSparrow%2C+David%3BHu%2C+Howard&rft.aulast=Tsaih&rft.aufirst=Shirng-Wern&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1178&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD LEAD LEVEL; CARDIOVASCULAR DISORDERS; NEPHROTOXICITY ER - TY - JOUR T1 - Using Human Disease Outbreaks as a Guide to Multilevel Ecosystem Interventions AN - 14705356; 10667545 AB - It has been suggested that disease incidence within a human population can be used as a bioindicator of ecosystem health. The incidence data most useful in this regard relate to vector-mediated diseases and infections that appear to transcend simple transmission categories. Examples are provided that show that many stresses and disruptions to natural ecosystem functioning can be identified only as a result of detailed epidemiologic investigations. By identifying the ecosystem disruption affecting human health using an outbreak-based approach, appropriate strategies for intervention and remediation can be introduced. Such examples are provided for ecosystem interventions for local, regional, and global outbreaks. JF - Environmental Health Perspectives AU - Cook, Angus AU - Jardine, Andrew AU - Weinstein, Philip Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1143 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - EPIDEMICS KW - BIOLOGICAL INDICATORS KW - ECOLOGY, HUMAN KW - ECOSYSTEM DYNAMICS KW - ECOLOGICAL IMBALANCE KW - DISEASES AND DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+Human+Disease+Outbreaks+as+a+Guide+to+Multilevel+Ecosystem+Interventions&rft.au=Cook%2C+Angus%3BJardine%2C+Andrew%3BWeinstein%2C+Philip&rft.aulast=Cook&rft.aufirst=Angus&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1143&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 58 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - EPIDEMICS; ECOSYSTEM DYNAMICS; ECOLOGICAL IMBALANCE; BIOLOGICAL INDICATORS; DISEASES AND DISORDERS; ECOLOGY, HUMAN ER - TY - JOUR T1 - Assessment of Prediction Confidence and Domain Extrapolation of Two StructureActivity Relationship Models for Predicting Estrogen Receptor Binding Activity AN - 14704253; 10667801 JF - Environmental Health Perspectives AU - Tong, Weida AU - Xie, Qian AU - Hong, Huixiao AU - Shi, Leming AU - Fang, Hong AU - Perkins, Roger Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1249 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHEMICAL ANALYSIS KW - HORMONAL EFFECTS KW - QUANTITATIVE STRUCTURE-ACTIVITY RELATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Prediction+Confidence+and+Domain+Extrapolation+of+Two+Structure%26lt%3BND%26gt%3BActivity+Relationship+Models+for+Predicting+Estrogen+Receptor+Binding+Activity&rft.au=Tong%2C+Weida%3BXie%2C+Qian%3BHong%2C+Huixiao%3BShi%2C+Leming%3BFang%2C+Hong%3BPerkins%2C+Roger&rft.aulast=Tong&rft.aufirst=Weida&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1249&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL ANALYSIS; HORMONAL EFFECTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATION ER - TY - JOUR T1 - Age-Related Differences in Susceptibility to Carcinogenesis: a Quantitative Analysis of Empirical Animal Bioassay Data AN - 14703691; 10667547 AB - Results are presented from a statistically weighted analysis of relative cancer potency in terms of cancer transformations per animal per unit dose for animals in different age groups, scaled to the highest experimental dose used either in adult animals or the oldest age group of animals included in the experiment. Separate relative potency estimates were derived for the fetal, birthweaning, and weaning60-d periods. The databases used in the assessment are describe briefly, as are the modeling methods applied. Results are presented for overall continuous chemical, discrete chemical, and radiation dosing data sets; for mutagenic versus nonmutagenic chemicals; for male versus female animals; for rats versus mice; for direct-acting carcinogens versus agents requiring metabolic activation; for direct dosing in the birthweaning period versus dosing via lactation; and for liver tumors versus tumors in other organs. The results reveal a significant increased carcinogenic sensitivity in the birthweaning period per dose for mutagenic carcinogens and a somewhat smaller increase for radiation carcinogensis per gray. JF - Environmental Health Perspectives AU - Hattis, Dale AU - Goble, Robert AU - Russ, Abel AU - Chu, Margaret AU - Ericson, Jen Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1152 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CARCINOGENIC MECHANISMS KW - SUSCEPTIBILITY KW - BIOASSAY KW - MATHEMATIC MODELS, CARCINOGENESIS KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703691?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Age-Related+Differences+in+Susceptibility+to+Carcinogenesis%3A+a+Quantitative+Analysis+of+Empirical+Animal+Bioassay+Data&rft.au=Hattis%2C+Dale%3BGoble%2C+Robert%3BRuss%2C+Abel%3BChu%2C+Margaret%3BEricson%2C+Jen&rft.aulast=Hattis&rft.aufirst=Dale&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1152&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CARCINOGENIC MECHANISMS; SUSCEPTIBILITY; BIOASSAY; MATHEMATIC MODELS, CARCINOGENESIS; AGE COMPARISONS ER - TY - JOUR T1 - Increased Risk of Hepatocellular Carcinoma and Liver Cirrhosis in Vinyl Chloride Workers: Synergistic Effect of Occupational Exposure and Alcohol Intake AN - 14703681; 10667553 JF - Environmental Health Perspectives AU - Mastrangelo, Giuseppe AU - Fedeli, Ugo AU - Fadda, Emanuela AU - Valentini, Flavio AU - Agnesi, Roberto AU - Magarotto, Giancarlo AU - Marchi, Teresio Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1188 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - ALCOHOLS KW - SYNERGISTIC EFFECTS KW - HEALTH SAFETY, OCCUPATIONAL KW - VINYL CHLORIDE KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703681?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Increased+Risk+of+Hepatocellular+Carcinoma+and+Liver+Cirrhosis+in+Vinyl+Chloride+Workers%3A+Synergistic+Effect+of+Occupational+Exposure+and+Alcohol+Intake&rft.au=Mastrangelo%2C+Giuseppe%3BFedeli%2C+Ugo%3BFadda%2C+Emanuela%3BValentini%2C+Flavio%3BAgnesi%2C+Roberto%3BMagarotto%2C+Giancarlo%3BMarchi%2C+Teresio&rft.aulast=Mastrangelo&rft.aufirst=Giuseppe&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1188&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; HEALTH SAFETY, OCCUPATIONAL; VINYL CHLORIDE; HEPATOTOXICITY; ALCOHOLS; SYNERGISTIC EFFECTS ER - TY - JOUR T1 - Determinants of Bone and Blood Lead Levels Among Minorities Living in the Boston Area AN - 14703660; 10667546 AB - Blood and bone lead levels were measured in exclusively minority subjects living in the Boston, MA, area. In total, 84 subjects participated, and the mean and median blood Pb levels were 3.0 and 2.2 mu g/dl, respectively, while the mean tibia and patella Pb levels were 11.9 and 14.2 mu g/g, respectively. The associations between age and bone Pb biomarkers were found to be nonlinear, with higher levels found in subjects greater than 55 yr of age, and within the older age group, males exhibited a higher rate of blood and patella Pb accumulation than females. JF - Environmental Health Perspectives AU - Lin, Charles AU - Kim, Rokho AU - Tsaih, Shirng-Wern AU - Sparrow, David AU - Hu, Howard Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1147 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - MINORITIES KW - BLOOD LEAD LEVEL KW - MASSACHUSETTS KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703660?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Determinants+of+Bone+and+Blood+Lead+Levels+Among+Minorities+Living+in+the+Boston+Area&rft.au=Lin%2C+Charles%3BKim%2C+Rokho%3BTsaih%2C+Shirng-Wern%3BSparrow%2C+David%3BHu%2C+Howard&rft.aulast=Lin&rft.aufirst=Charles&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1147&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; MINORITIES; BLOOD LEAD LEVEL; MASSACHUSETTS; AGE COMPARISONS ER - TY - JOUR T1 - The Effect of Arsenic Mitigation Interventions on Disease Burden in Bangladesh AN - 14703547; 10667550 AB - In Bangladesh, mortality rates and disability-adjusted life years lost were calculated for arsenic-related disease and waterborne infectious disease to evaluate the possible change in overall disease burden resulting from the implementation of As mitigation interventions involving improvements in water supply and sanitation services. Results showed that much of the benefit obtained from intervention appeared to be negated by a concomitant increase in water-related infectious disease. JF - Environmental Health Perspectives AU - Lokuge, Kamalini M AU - Smith, Wayne AU - Caldwell, Bruce AU - Dear, Keith AU - Milton, Abul H Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1172 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MITIGATIVE MEASURES KW - ARSENIC KW - DISEASES AND DISORDERS KW - BANGLADESH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703547?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Effect+of+Arsenic+Mitigation+Interventions+on+Disease+Burden+in+Bangladesh&rft.au=Lokuge%2C+Kamalini+M%3BSmith%2C+Wayne%3BCaldwell%2C+Bruce%3BDear%2C+Keith%3BMilton%2C+Abul+H&rft.aulast=Lokuge&rft.aufirst=Kamalini&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1172&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MITIGATIVE MEASURES; DISEASES AND DISORDERS; ARSENIC; BANGLADESH ER - TY - JOUR T1 - Biokinetics and Subchronic Toxic Effects of Oral Arsenite, Arsenate, Monomethylarsonic Acid, and Dimethylarsinic Acid in v-Ha-ras Transgenic (Tg.AC) Mice AN - 14703040; 10667802 AB - The effects of subchronic inorganic and organic arsenical exposure on the v-Ha-ras transgenic (Tg.AC) mouse liver were examined. Mice were assigned randomly to five groups that were provided unaltered drinking water or drinking water containing arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid at concentrations of 150, 200, 1500, and 1000 ppm as As, respectively, for 17 weeks. After four weeks of exposure, 12-O-tetradecanoylphorbol-13-acetate was applied twice weekly for two weeks to the shaved dorsal skin of all mice. Arsenic-induced toxicity was evidenced by an increase in moribundity and death, a depression in body weight, hepatic pathological changes, and significant changes in gene expression. Hepatic As accumulation, based on biokinetic analyses, was dose-dependent, and global DNA hypomethylation occurred after exposure to all four arsenicals. Among the 600 genes examined via microarry analysis, 70 displayed increased or decreased expression. All arsenicals produced increases in glutathione S-transferases and fibroblast growth factor 2, and a significant increase was observed in the expression of insulin-like growth factor binding protein 1 in monomethylarsonic acid-treated animals. JF - Environmental Health Perspectives AU - Xie, Yaxiong AU - Trouba, Kevin J AU - Liu, Jie AU - Waalkes, Michael P AU - Germolec, Dori R Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1255 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ARSENATES KW - GENETICS, ANIMAL KW - ARSENIC KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biokinetics+and+Subchronic+Toxic+Effects+of+Oral+Arsenite%2C+Arsenate%2C+Monomethylarsonic+Acid%2C+and+Dimethylarsinic+Acid+in+v-Ha-ras+Transgenic+%28Tg.AC%29+Mice&rft.au=Xie%2C+Yaxiong%3BTrouba%2C+Kevin+J%3BLiu%2C+Jie%3BWaalkes%2C+Michael+P%3BGermolec%2C+Dori+R&rft.aulast=Xie&rft.aufirst=Yaxiong&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1255&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; ARSENATES; ARSENIC; HEPATOTOXICITY ER - TY - JOUR T1 - Vaccines for other neonatal infections: Pneumococcal disease: a major global health problem of young children AN - 1257721744; 16614434 AB - Provided the high vaccine costs for pneumococcal conjugate vaccines can be addressed for the poorest countries, neonatal PCV immunization offers the hope of decreasing the significant morbidity that occurs in these vulnerable populations. JF - Expert Review of Vaccines AU - Richmond, Peter AD - University of WA School of Pediatrics and Child Health, Princess Margaret Hospital for Children, GPO Box D184, Perth WA 6840, Australia. peterrchr.uwa.edu.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 379 EP - 382 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 3 IS - 4 SN - 1476-0584, 1476-0584 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Children KW - Health problems KW - Immunization KW - Infection KW - Morbidity KW - Neonates KW - Reviews KW - Vaccines KW - Vulnerability KW - immunization KW - Streptococcus pneumoniae KW - J 02350:Immunology KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257721744?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Vaccines&rft.atitle=Vaccines+for+other+neonatal+infections%3A+Pneumococcal+disease%3A+a+major+global+health+problem+of+young+children&rft.au=Richmond%2C+Peter&rft.aulast=Richmond&rft.aufirst=Peter&rft.date=2004-08-01&rft.volume=3&rft.issue=4&rft.spage=379&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Vaccines&rft.issn=14760584&rft_id=info:doi/10.1586%2F14760584.3.4.379 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2013-02-22 N1 - SubjectsTermNotLitGenreText - Reviews; Neonates; Vaccines; Children; Infection; Immunization; Morbidity; immunization; Health problems; Vulnerability; Streptococcus pneumoniae DO - http://dx.doi.org/10.1586/14760584.3.4.379 ER - TY - JOUR T1 - Table: Fiscal 2005 Defense Operation and Maintenance Budget and Military Personnel Budget; AN - 231471099 AB - Service___ Budget___ House ___ Senate ___ Conference Environmental restoration, Navy___ 266,820___ 266,820___ 447,820___ 266,820 Service___ Budget___ House ___ Senate ___ Conference JF - Aerospace Daily & Defense Report AU - U.S. Congress AD - U.S. Congress Y1 - 2004/07/29/ PY - 2004 DA - 2004 Jul 29 SP - 8 CY - Washington PB - Penton Media, Inc., Penton Business Media, Inc. VL - 211 IS - 1 SN - 15538591 KW - Aeronautics And Space Flight UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/231471099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabitrade&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerospace+Daily+%26+Defense+Report&rft.atitle=Table%3A+Fiscal+2005+Defense+Operation+and+Maintenance+Budget+and+Military+Personnel+Budget%3B&rft.au=U.S.+Congress&rft.aulast=U.S.+Congress&rft.aufirst=&rft.date=2004-07-29&rft.volume=211&rft.issue=1&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=Aerospace+Daily+%26+Defense+Report&rft.issn=15538591&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Name - Air National Guard N1 - Copyright - Copyright (c) 2004 The McGraw-Hill Companies, Inc. All rights reserved. N1 - Last updated - 2015-01-03 N1 - CODEN - ENVRAL ER - TY - JOUR T1 - Table: Fiscal 2005 Defense Appropriations Research, Development, Test and Evaluation; AN - 231588930 AB - Service___ Budget___ House ___ Senate ___ Conference Operational Test and Evaluation, Defense___ 305,135___ 309,135___ 305,135___ 314,835 JF - Aerospace Daily & Defense Report AU - U.S. Congress AD - U.S. Congress Y1 - 2004/07/28/ PY - 2004 DA - 2004 Jul 28 SP - 6 CY - Washington PB - Penton Media, Inc., Penton Business Media, Inc. VL - 211 IS - 19 SN - 15538591 KW - Aeronautics And Space Flight UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/231588930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabitrade&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerospace+Daily+%26+Defense+Report&rft.atitle=Table%3A+Fiscal+2005+Defense+Appropriations+Research%2C+Development%2C+Test+and+Evaluation%3B&rft.au=U.S.+Congress&rft.aulast=U.S.+Congress&rft.aufirst=&rft.date=2004-07-28&rft.volume=211&rft.issue=19&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Aerospace+Daily+%26+Defense+Report&rft.issn=15538591&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright (c) 2004 The McGraw-Hill Companies, Inc. All rights reserved. N1 - Last updated - 2015-01-03 N1 - CODEN - ENVRAL ER - TY - JOUR T1 - Fiscal 2005 Defense Appropriations Procurement; AN - 231527426 AB - Missiles___________________________1,398,321____1,327,000____1,378,321____1,307,000 Weapons, tracked combat vehicles___1,639,695____2,773,695____1,698,695____2,467,495 Total, Navy___27,714,444___28,353,273___28,238,598___28,650,534 JF - Aerospace Daily & Defense Report AU - U.S. Congress AD - U.S. Congress Y1 - 2004/07/26/ PY - 2004 DA - 2004 Jul 26 SP - 6 CY - Washington PB - Penton Media, Inc., Penton Business Media, Inc. VL - 211 IS - 17 SN - 15538591 KW - Aeronautics And Space Flight UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/231527426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabitrade&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerospace+Daily+%26+Defense+Report&rft.atitle=Fiscal+2005+Defense+Appropriations+Procurement%3B&rft.au=U.S.+Congress&rft.aulast=U.S.+Congress&rft.aufirst=&rft.date=2004-07-26&rft.volume=211&rft.issue=17&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Aerospace+Daily+%26+Defense+Report&rft.issn=15538591&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright (c) 2004 The McGraw-Hill Companies, Inc. All rights reserved. N1 - Last updated - 2015-01-03 N1 - CODEN - ENVRAL ER - TY - JOUR T1 - An a posteriori strategy for enhancing gene discovery in anonymous cDNA microarray experiments AN - 18007709; 5956847 AB - MOTIVATION: Because of the high cost of sequencing, the bulk of gene discovery is performed using anonymous cDNA microarrays. Though the clones on such arrays are easier and cheaper to construct and utilize than unigene and oligonucleotide arrays, they are there in proportion to their corresponding gene expression activity in the tissue being examined. The associated redundancy will be there in any pool of possibly interesting differentially expressed clones identified in a microarray experiment for subsequent sequencing and investigation. An a posteriori sampling strategy is proposed to enhance gene discovery by reducing the impact of the redundancy in the identified pool. RESULTS: The proposed strategy exploits the fact that individual genes that are highly expressed in a tissue are more likely to be present as a number of spots in an anonymous library and, as a direct consequence, are also likely to give higher fluorescence intensity responses when present in a probe in a cDNA microarray experiment. Consequently, spots that respond with low intensities will have a lower redundancy and so should be sequenced in preference to those with the highest intensities. The proposed method, which formalizes how the fluorescence intensity of a spot should be assessed, is validated using actual microarray data, where the sequences of all the clones in the identified pool had been previously determined. For such validations, the concept of a repeat plot is introduced. It is also utilized to visualize and examine different measures for the characterization of fluorescence intensity. In addition, as confirmatory evidence, sequencing from the lowest to the highest intensities in a pool, with all the sequences known, is compared graphically with their random sequencing. The results establish that, in general, the opportunity for gene discovery is enhanced by avoiding the pooling of different biological libraries (because their construction will have involved different hybridization episodes) and concentrating on the clones with lower fluorescence intensities. JF - Bioinformatics AU - Anderssen, R S AU - Wu, Y AU - Dolferus, R AU - Saunders, I AD - CSIRO Mathematical and Information Sciences, GPO Box 664, Canberra ACT 2601, CSIRO Plant Industry and Cotton R&D Corporation and CSIRO Plant Industry and CRC for Sustainable Rice Production, GPO Box 1600, Canberra ACT 2601, Australia Y1 - 2004/07/22/ PY - 2004 DA - 2004 Jul 22 SP - 1721 EP - 1727 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 20 IS - 11 SN - 1367-4803, 1367-4803 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - Gene expression KW - Fluorescence KW - DNA microarrays KW - Hybridization analysis KW - N 14510:Occurrence, isolation & assay KW - W 30965:Miscellaneous, Reviews KW - W4 350:Bioinformatics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18007709?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioinformatics&rft.atitle=An+a+posteriori+strategy+for+enhancing+gene+discovery+in+anonymous+cDNA+microarray+experiments&rft.au=Anderssen%2C+R+S%3BWu%2C+Y%3BDolferus%2C+R%3BSaunders%2C+I&rft.aulast=Anderssen&rft.aufirst=R&rft.date=2004-07-22&rft.volume=20&rft.issue=11&rft.spage=1721&rft.isbn=&rft.btitle=&rft.title=Bioinformatics&rft.issn=13674803&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Fluorescence; Hybridization analysis; Gene expression; DNA microarrays ER - TY - JOUR T1 - Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GC x GC-TOFMS) for drug screening and confirmation. AN - 66686090; 15240028 AB - Comprehensive two-dimensional gas chromatography (GC x GC) is applied to analysis of drug standard mixtures containing 78 drugs of interest in forensic samples. For this study, underivatised drugs were employed. While several of the drugs were not detected at the low concentrations employed in the samples, most could be satisfactorily assigned their first and second dimension retentions in the GC x GC retention plane. For this study, time-of-flight mass spectrometry (TOFMS) detection was used. The enhanced separation possible in GC x GC is demonstrated, and typical linearity and apparatus precision are shown for tramadol, diazepam, olanzapine and desipramine using selected qualifier ions. Mass spectral library search quality for the detection of drugs in a selection of authentic forensic cases, along with retention position in the 2D retention plane, is used to support positive identification of the presence of the drugs. The analysis of 'difficult' drugs paracetamol and phenytoin is shown to produce anomalous chromatographic peak shape in the 2D plane, whereas most drugs gave acceptable peak shapes. The GC x GC technique was applied to screening drugs in forensic samples, with either flame ionisation (FID) or TOFMS detection, and compared favourably with conventional single column GC-MS analysis when tested for diazepam in an authentic forensic study. JF - Forensic science international AU - Song, Shin Miin AU - Marriott, Philip AU - Kotsos, Alex AU - Drummer, Olaf H AU - Wynne, Paul AD - Department of Applied Chemistry, Australian Centre for Research on Separation Science, Rmit University, Building 3, Bowen St., 124 Latrobe St., GPO Box 2476 V, Melbourne, Vic. 3001. Y1 - 2004/07/16/ PY - 2004 DA - 2004 Jul 16 SP - 87 EP - 101 VL - 143 IS - 2-3 SN - 0379-0738, 0379-0738 KW - Index Medicus KW - Substance-Related Disorders -- blood KW - Humans KW - Gas Chromatography-Mass Spectrometry -- methods KW - Forensic Medicine -- methods KW - Substance Abuse Detection -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66686090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forensic+science+international&rft.atitle=Comprehensive+two-dimensional+gas+chromatography+with+time-of-flight+mass+spectrometry+%28GC+x+GC-TOFMS%29+for+drug+screening+and+confirmation.&rft.au=Song%2C+Shin+Miin%3BMarriott%2C+Philip%3BKotsos%2C+Alex%3BDrummer%2C+Olaf+H%3BWynne%2C+Paul&rft.aulast=Song&rft.aufirst=Shin&rft.date=2004-07-16&rft.volume=143&rft.issue=2-3&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Forensic+science+international&rft.issn=03790738&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-01 N1 - Date created - 2004-07-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Money Laundering and Foreign Corruption: Enforcement and Effectiveness of the PATRIOT Act, Case Study Involving Riggs Bank AN - 1679125980; CL02834 AB - Demonstrates Riggs Bank's complicity in hiding Augusto Pinochet's accounts from law enforcement officials attempting to freeze his assets and other illegal and questionable acts. AU - United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations. Minority Staff AD - United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations. Minority Staff PY - 2004 SP - 22 KW - Banks KW - Congressional hearings KW - Corporate corruption KW - Crime KW - Equatorial Guinea KW - Frozen assets KW - Laundering of funds KW - Spain KW - United Kingdom UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679125980?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_cl&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Money+Laundering+and+Foreign+Corruption%3A+Enforcement+and+Effectiveness+of+the+PATRIOT+Act%2C+Case+Study+Involving+Riggs+Bank&rft.au=United+States.+Congress.+Senate.+Committee+on+Governmental+Affairs.+Permanent+Subcommittee+on+Investigations.+Minority+Staff&rft.aulast=United+States.+Congress.+Senate.+Committee+on+Governmental+Affairs.+Permanent+Subcommittee+on+Investigations.+Minority+Staff&rft.aufirst=&rft.date=2004-07-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - Althorp Investment Company, Ltd.; Ashburton Company, Ltd.; Riggs Bank, N.A.; United States. Department of the Treasury. Office of the Comptroller of the Currency N1 - Analyte descriptor - NSA document type: Report N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - Cultural and ethical issues in working with culturally diverse patients and their families: The use of the culturagram to promote cultural competent practice in health care settings AN - 210845268 AB - In all aspects of health and mental health care-the emergency room, the outpatient clinic, inpatient facilities, rehab centers, nursing homes, and hospices-social workers interact with patients from many different cultures. This paper will introduce an assessment tool for health care professionals to advance understanding of culturally diverse patients and their families. [PUBLICATION ABSTRACT] JF - Social Work in Health Care AU - Congress, Elaine P Y1 - 2004 PY - 2004 DA - 2004 SP - 249 EP - 262 CY - New York PB - Taylor & Francis Group VL - 39 IS - 3/4 SN - 00981389 KW - Social Services And Welfare KW - Ethics KW - Patients KW - Multiculturalism & pluralism KW - Health care KW - Families & family life UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/210845268?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apsychology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Work+in+Health+Care&rft.atitle=Cultural+and+ethical+issues+in+working+with+culturally+diverse+patients+and+their+families%3A+The+use+of+the+culturagram+to+promote+cultural+competent+practice+in+health+care+settings&rft.au=Congress%2C+Elaine+P&rft.aulast=Congress&rft.aufirst=Elaine&rft.date=2004-07-10&rft.volume=39&rft.issue=3%2F4&rft.spage=249&rft.isbn=&rft.btitle=&rft.title=Social+Work+in+Health+Care&rft.issn=00981389&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright Haworth Press, Inc. 2004 N1 - Last updated - 2010-06-08 N1 - CODEN - SWHCDO ER - TY - BOOK T1 - Report on the U.S. intelligence community's prewar intelligence assessments on Iraq: ordered reported on July 7, 2004 T2 - 108th Cong. AN - 58844469; 2004-0803220 AB - Presents US intelligence analysis of Iraq's programs for weapons of mass destruction (WMD), including nuclear, biological, and chemical weapons programs, delivery systems, and links to terrorism. JF - United States Senate, July 7 2004. Y1 - 2004/07/07/ PY - 2004 DA - 2004 Jul 07 PB - United States Senate KW - Weapons of mass destruction -- Iraq KW - Terrorism -- Iraq KW - Government investigations -- United States KW - Atomic weapons -- Iraq KW - Iraq -- Defenses KW - Chemical weapons -- Iraq KW - United States -- Intelligence service KW - Biological weapons -- Iraq UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58844469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Report+on+the+U.S.+intelligence+community%27s+prewar+intelligence+assessments+on+Iraq%3A+ordered+reported+on+July+7%2C+2004&rft.title=Report+on+the+U.S.+intelligence+community%27s+prewar+intelligence+assessments+on+Iraq%3A+ordered+reported+on+July+7%2C+2004&rft.issn=&rft_id=info:doi/ L2 - http://intelligence.senate.gov/iraqreport2.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Senate N1 - Document feature - table(s) N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Public water sources in rural watersheds of Nepal's Middle Mountains: issues and constraints. AN - 66898462; 15156351 AB - Inadequacy and poor quality of water supply for domestic purposes is increasingly becoming a concern in rural catchments of the Middle Mountains of Nepal. Water quantity is an issue in pocket areas of these catchments, while water quality is subject to concern in most of the water sources. Microbiological contamination in particular poses a risk to human health. In addition, sediment pollution during the monsoon season is perceived as an issue by the local residents. Elevated phosphate and nitrate levels in many water sources indicate intensive interaction with surface water hailing from agricultural areas and human settlements. These water quantity and quality concerns in two watersheds of Nepal, the Jhikhu Khola and the Yarsha Khola watersheds, are not isolated cases. Similar problems are reported from other watersheds monitored under the People and Resource Dynamics in Mountain Watersheds of the Hindu Kush-Himalayas (PARDYP) project in China, India, and Pakistan and the literature of this region. JF - Environmental management AU - Merz, Juerg AU - Nakarmi, Gopal AU - Shrestha, Smita AU - Dahal, Bed M AU - Dongol, Bhawani S AU - Schaffner, Monika AU - Shakya, Sangeeta AU - Sharma, Subodh AU - Weingartner, Rolf AD - PARDYP/International Centre for Integrated Mountain Development, GPO Box 3226, Kathmandu, Nepal. jmerz@icimod.org.np Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 26 EP - 37 VL - 34 IS - 1 SN - 0364-152X, 0364-152X KW - Water Pollutants KW - 0 KW - Index Medicus KW - Environmental Monitoring KW - Altitude KW - Humans KW - Data Collection KW - Water Microbiology KW - Geologic Sediments KW - Nepal KW - Water Supply -- economics KW - Public Sector KW - Water Pollutants -- analysis KW - Water Supply -- standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66898462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+management&rft.atitle=Public+water+sources+in+rural+watersheds+of+Nepal%27s+Middle+Mountains%3A+issues+and+constraints.&rft.au=Merz%2C+Juerg%3BNakarmi%2C+Gopal%3BShrestha%2C+Smita%3BDahal%2C+Bed+M%3BDongol%2C+Bhawani+S%3BSchaffner%2C+Monika%3BShakya%2C+Sangeeta%3BSharma%2C+Subodh%3BWeingartner%2C+Rolf&rft.aulast=Merz&rft.aufirst=Juerg&rft.date=2004-07-01&rft.volume=34&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Environmental+management&rft.issn=0364152X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-10-18 N1 - Date created - 2004-09-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - [Polyfection as nonviral gene transfer method -design of novel nonviral vector using alpha-cyclodextrin]. AN - 66680988; 15235229 AB - Due to the growing concerns over the toxicity and immunogenicity of viral DNA delivery systems, DNA delivery via nonviral routes has become more desirable and advantageous. In particular, polycation complexes with DNA (polyplex) are attractive nonviral vectors. To design novel polycationic vectors, we prepared polyamidoamine starburst dendrimer (dendrimer) conjugates with three cyclodextrins (CDE conjugates) and three generations (G2, G3, and G4) of dendrimers. Of seven CDE conjugates, an alpha-CDE conjugate (G3) with an average degree of substitution (DS) of alpha-CyD of 2.4 [alpha-CDE conjugate (G3, DS 2.4)] showed greater gene transfer activity than dendrimers and other alpha-CDE conjugates with less cytotoxicity. These results suggest the potential use of alpha-CDE conjugate (G3, DS 2.4) as a polycationic vector in vitro and in vivo. Herein, I review a recent polyfection method, with special focus on alpha-CDE conjugate (G3, DS 2.4). JF - Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan AU - Arima, Hidetoshi AD - Graduate School of Pharmaceutical Sciences, Kumamoto University, Japan. arimah@gpo.kumamoto-u.ac.jp Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 451 EP - 464 VL - 124 IS - 7 SN - 0031-6903, 0031-6903 KW - Cyclodextrins KW - 0 KW - Dendrimers KW - PAMAM Starburst KW - Polyamines KW - alpha-Cyclodextrins KW - polycations KW - alpha-cyclodextrin KW - Z1LH97KTRM KW - Index Medicus KW - Gene Transfer Techniques KW - Genetic Vectors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66680988?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Yakugaku+zasshi+%3A+Journal+of+the+Pharmaceutical+Society+of+Japan&rft.atitle=%5BPolyfection+as+nonviral+gene+transfer+method+-design+of+novel+nonviral+vector+using+alpha-cyclodextrin%5D.&rft.au=Arima%2C+Hidetoshi&rft.aulast=Arima&rft.aufirst=Hidetoshi&rft.date=2004-07-01&rft.volume=124&rft.issue=7&rft.spage=451&rft.isbn=&rft.btitle=&rft.title=Yakugaku+zasshi+%3A+Journal+of+the+Pharmaceutical+Society+of+Japan&rft.issn=00316903&rft_id=info:doi/ LA - Japanese DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-27 N1 - Date created - 2004-07-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Changes in ion fluxes during phototropic bending of etiolated oat coleoptiles. AN - 66652849; 15155378 AB - This work has been conducted to assist theoretical modelling of the different stages of the blue light (BL)-induced phototropic signalling pathway and ion transport activity across plant membranes. Ion fluxes (Ca(2+), H(+), K(+) and Cl(-)) in etiolated oat coleoptiles have been measured continuously before and during unilateral BL exposure. Changes in ion fluxes at the illuminated (light) and shadowed (dark) sides of etiolated oat coleoptiles (Avena sativa) were studied using a non-invasive ion-selective microelectrode technique (MIFE). The bending response was also measured continuously, and correlations between the changes in various ion fluxes and bending response have been investigated. For each ion the difference (Delta) between the magnitudes of flux at the light and dark sides of the coleoptile was calculated. Plants that demonstrated a phototropic bending response also demonstrated Ca(2+) influx into the light side approximately 20 min after the start of BL exposure. This is regarded as part of the perception and transduction stages of the BL-induced signal cascade. The first 10 min of bending were associated with substantial influx of H(+), K(+) and Cl(-) into the light (concave) side of the coleoptiles. The data suggest that Ca(2+) participates in the signalling stage of the BL-induced phototropism, whereas the phototropic bending response is linked to changes in the transport of H(+), K(+) and Cl(-). JF - Annals of botany AU - Babourina, Olga AU - Godfrey, Leith AU - Voltchanskii, Konstantin AD - School of Mathematics and Physics, University of Tasmania, GPO Box 252-21, Hobart, Tasmania 7001, Australia. obabouri@agric.uwa.edu.au Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 187 EP - 194 VL - 94 IS - 1 SN - 0305-7364, 0305-7364 KW - Chlorine KW - 4R7X1O2820 KW - Hydrogen KW - 7YNJ3PO35Z KW - Potassium KW - RWP5GA015D KW - Calcium KW - SY7Q814VUP KW - Index Medicus KW - Darkness KW - Calcium -- metabolism KW - Hydrogen -- metabolism KW - Light KW - Cell Membrane -- metabolism KW - Time Factors KW - Chlorine -- metabolism KW - Signal Transduction KW - Potassium -- metabolism KW - Models, Theoretical KW - Phototropism KW - Cotyledon -- growth & development KW - Avena -- metabolism KW - Avena -- growth & development KW - Cotyledon -- radiation effects KW - Avena -- radiation effects KW - Cotyledon -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66652849?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+botany&rft.atitle=Changes+in+ion+fluxes+during+phototropic+bending+of+etiolated+oat+coleoptiles.&rft.au=Babourina%2C+Olga%3BGodfrey%2C+Leith%3BVoltchanskii%2C+Konstantin&rft.aulast=Babourina&rft.aufirst=Olga&rft.date=2004-07-01&rft.volume=94&rft.issue=1&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Annals+of+botany&rft.issn=03057364&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-09-24 N1 - Date created - 2004-06-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Why We Must End Insurance Discrimination against Mental Health Care AN - 60725282; 200503271 AB - In this Policy Essay, Representative Patrick Kennedy argues that insurance discrimination against those suffering from mental illnesses constitutes a serious & often overlooked deficiency of the modern American health care system. While the Mental Health Parity Act of 1996 was an important step toward resolution of this issue, many loopholes remain that allow insurance companies to deny much-needed coverage to those suffering from such illnesses. This Essay details how improving access to health insurance for the mentally ill is not only socially beneficial, but also economically sound; the cost of instituting mental health parity is far outweighed by the costs that employers bear because of the reduced productivity of untreated mental illness sufferers. Representative Kennedy recommends that these problems may be addressed by additional mental health parity legislation -- specifically, the proposed Paul Wellstone Act. Adapted from the source document. JF - Harvard Journal on Legislation AU - Kennedy, Patrick J AD - United States House of Representatives Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 363 EP - 375 VL - 41 IS - 2 SN - 0017-808X, 0017-808X KW - Health Care Services Policy KW - Mental Patients KW - Health Insurance KW - Discrimination KW - Mental Health Services KW - Legislation KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60725282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harvard+Journal+on+Legislation&rft.atitle=Why+We+Must+End+Insurance+Discrimination+against+Mental+Health+Care&rft.au=Kennedy%2C+Patrick+J&rft.aulast=Kennedy&rft.aufirst=Patrick&rft.date=2004-07-01&rft.volume=41&rft.issue=2&rft.spage=363&rft.isbn=&rft.btitle=&rft.title=Harvard+Journal+on+Legislation&rft.issn=0017808X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Mental Health Services; Health Insurance; Mental Patients; Discrimination; Legislation; Health Care Services Policy ER - TY - JOUR T1 - Commerce with a Conscience: Balancing Privacy and Profit in a Digital World AN - 60695673; 200503300 AB - In this Policy Essay, Representative Edward J. Markey discusses changes in regulations governing patient privacy that have been recently implemented by the Department of Heath & Human Services. Representative Markey argues that in the areas of patient consent & marketing, these changes have favored business interests at the expense of patient privacy. To correct this imbalance Representative Markey argues that Congress should pass the STOHP Act, which would protect patient privacy by restoring consent requirements & limitations on marketing by health care providers. Adapted from the source document. JF - Harvard Journal on Legislation AU - Markey, Edward J AD - United States House of Representatives Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 377 EP - 388 VL - 41 IS - 2 SN - 0017-808X, 0017-808X KW - Patients Rights KW - Privacy KW - Informed Consent KW - Health Policy KW - Legislation KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60695673?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harvard+Journal+on+Legislation&rft.atitle=Commerce+with+a+Conscience%3A+Balancing+Privacy+and+Profit+in+a+Digital+World&rft.au=Markey%2C+Edward+J&rft.aulast=Markey&rft.aufirst=Edward&rft.date=2004-07-01&rft.volume=41&rft.issue=2&rft.spage=377&rft.isbn=&rft.btitle=&rft.title=Harvard+Journal+on+Legislation&rft.issn=0017808X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Patients Rights; Privacy; Informed Consent; Health Policy; Legislation ER - TY - JOUR T1 - Collaboration as a Means to Formulating Mutually Beneficial Environmental Policy AN - 60680210; 200503193 AB - In this Policy Essay, United States Senator Mike Crapo discusses the value of local collaboration in the development of mutually beneficial environmental policy. Using two examples of collaborative efforts in ID, Senator Crapo argues that policy development through collaboration at the local level is more efficient, avoids litigation, increases access to decision making, & leads to more stable policy. Adapted from the source document. JF - Harvard Journal on Legislation AU - Crapo, Mike AD - United States Senate Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 351 EP - 361 VL - 41 IS - 2 SN - 0017-808X, 0017-808X KW - Idaho KW - Policy Making KW - Cooperation KW - Environmental Policy KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60680210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harvard+Journal+on+Legislation&rft.atitle=Collaboration+as+a+Means+to+Formulating+Mutually+Beneficial+Environmental+Policy&rft.au=Crapo%2C+Mike&rft.aulast=Crapo&rft.aufirst=Mike&rft.date=2004-07-01&rft.volume=41&rft.issue=2&rft.spage=351&rft.isbn=&rft.btitle=&rft.title=Harvard+Journal+on+Legislation&rft.issn=0017808X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Policy Making; Environmental Policy; Cooperation; Idaho ER - TY - JOUR T1 - Ahmad Chalabi: "The Biggest Error Was Occupation" AN - 60676521; 200500702 AB - An interview with Iraqi National Congress leader Ahmad Chalabi that addresses the future development of Iraq, the US's involvement in Iraqi liberation, the process of de-Baathification in Iraq, the international community's accusations of wrongdoing against Chalabi, & the extent of corruption in the UN oil-for-food program in Iraq is presented. Questions concerning whether Iraq's interim government will engender a legitimate democracy, minority groups' right to self-determination, & the formation of Iraq's legislature are addressed. It is contended that the US should not have occupied Iraq following Operation Iraqi Freedom & that a provisional Iraqi government should have been established prior to the ousting of Saddam Hussein. The issue of whether de-Baathification processes have been responsible for rebel insurgency throughout Iraq is then pondered. After exploring Chalabi's relations with Hussein following the US's capture of the latter, the international community's charges that Chalabi engaged in embezzlement & falsified reports of the Hussein regime's possession of weapons of mass destruction are countered. In addition, it is stated that Paul Bremer actually prevented the Iraqi Interim Government Council's examination of whether the United Nation's oil-for-food program in Iraq was indeed corrupt. J. W. Parker JF - Middle East Quarterly AU - Chalabi, Ahmad AD - Iraqi National Congress Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 69 EP - 77 VL - 11 IS - 3 SN - 1073-9467, 1073-9467 KW - Weapons KW - War KW - United States of America KW - Corruption KW - United Nations KW - Political Development KW - Iraq KW - article KW - 9063: international relations; international relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60676521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Middle+East+Quarterly&rft.atitle=Ahmad+Chalabi%3A+%22The+Biggest+Error+Was+Occupation%22&rft.au=Chalabi%2C+Ahmad&rft.aulast=Chalabi&rft.aufirst=Ahmad&rft.date=2004-07-01&rft.volume=11&rft.issue=3&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Middle+East+Quarterly&rft.issn=10739467&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - SuppNotes - Interview conducted by Michael Rubin. N1 - Last updated - 2016-09-28 N1 - CODEN - MEQUFZ N1 - SubjectsTermNotLitGenreText - Iraq; United States of America; War; United Nations; Corruption; Weapons; Political Development ER - TY - JOUR T1 - Minority's Status Laws in the European Union and in Hungary AN - 36549165; 3360710 JF - Central European political science review AU - Ieda, Osamu AU - Kántor, Zoltán AU - Schöpflin, György AU - Csergo, Zsuzsa AU - Goldgeier, James M AU - Halász, Iván AU - Majtényi, Balázs AU - Vízi, Balázs AD - European Parliament ; George Washington University ; Library of Congress ; Eötvös Lóránd University ; Eötvös Loránd University ; Corvinus University of Budapest Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 7 EP - 91 VL - 5 IS - 16 SN - 1586-4197, 1586-4197 KW - Political Science KW - Citizenship KW - Member states KW - Ethnicity KW - International law KW - Ethnic origin KW - Europe KW - Nationalism KW - Nation building KW - Post-communist societies KW - Hungary KW - European Union KW - Minority rights KW - European studies KW - Legislation KW - Domestic policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36549165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Central+European+political+science+review&rft.atitle=Minority%27s+Status+Laws+in+the+European+Union+and+in+Hungary&rft.au=Ieda%2C+Osamu%3BK%C3%A1ntor%2C+Zolt%C3%A1n%3BSch%C3%B6pflin%2C+Gy%C3%B6rgy%3BCsergo%2C+Zsuzsa%3BGoldgeier%2C+James+M%3BHal%C3%A1sz%2C+Iv%C3%A1n%3BMajt%C3%A9nyi%2C+Bal%C3%A1zs%3BV%C3%ADzi%2C+Bal%C3%A1zs&rft.aulast=Ieda&rft.aufirst=Osamu&rft.date=2004-07-01&rft.volume=5&rft.issue=16&rft.spage=7&rft.isbn=&rft.btitle=&rft.title=Central+European+political+science+review&rft.issn=15864197&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Collection of 7 articles N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 4541 1247; 9923 11979; 8131 11032 9705; 4435; 4429; 2280 2309 11032 9705; 8536; 7321; 3706 5574 10472; 4529 4534 10721 6737 4539 10727 9030; 7919 6772 9030; 8477 8476; 6743 7253; 171 87 129; 129 ER - TY - JOUR T1 - Virtual nationalism in comparative context: how unique is the Hungarian approach? AN - 36541190; 3360656 JF - Central European political science review AU - Csergo, Zsuzsa AU - Goldgeier, James M AD - George Washington University ; Library of Congress Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 40 EP - 56 VL - 5 IS - 16 SN - 1586-4197, 1586-4197 KW - Political Science KW - Citizenship KW - European law KW - Nationalism KW - Nation building KW - Post-communist societies KW - Hungary KW - European Union KW - Romania KW - Minority rights KW - European studies KW - Russia KW - Legislation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36541190?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Central+European+political+science+review&rft.atitle=Virtual+nationalism+in+comparative+context%3A+how+unique+is+the+Hungarian+approach%3F&rft.au=Csergo%2C+Zsuzsa%3BGoldgeier%2C+James+M&rft.aulast=Csergo&rft.aufirst=Zsuzsa&rft.date=2004-07-01&rft.volume=5&rft.issue=16&rft.spage=40&rft.isbn=&rft.btitle=&rft.title=Central+European+political+science+review&rft.issn=15864197&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 4541 1247; 9923 11979; 8536; 8131 11032 9705; 2280 2309 11032 9705; 7321; 8477 8476; 4529 4534 10721 6737 4539 10727 9030; 4536 7253 4529 4534 10721 6737 4539 10727 9030; 171 87 129; 352 119 129; 349 394 129 ER - TY - JOUR T1 - An Unrecognized Source of PCB Contamination in Schools and Other Buildings AN - 21348554; 7697185 AB - An investigation of 24 buildings in the Greater Boston Area revealed that one-third (8 of 24) contained caulking materials with polychlorinated biphenyl (PCB) content exceeding 50 ppm by weight, which is the U.S. Environmental Protection Agency (U.S. EPA) specified limit above which this material is considered to be PCB bulk product waste. These buildings included schools and other public buildings. In a university building where similar levels of PCB were found in caulking material, PCB levels in indoor air ranged from 111 to 393 ng/m super(3); and in dust taken from the building ventilation system, < 1 ppm to 81 ppm. In this building, the U.S. EPA mandated requirements for the removal and disposal of the PCB bulk product waste as well as for confirmatory sampling to ensure that the interior and exterior of the building were decontaminated. Although U.S. EPA regulations under the Toxic Substances Control Act stipulate procedures by which PCB-contaminated materials must be handled and disposed, the regulations apparently do not require that materials such as caulking be tested to determine its PCB content. This limited investigation strongly suggests that were this testing done, many buildings would be found to contain high levels of PCBs in the building materials and potentially in the building environment. The presence of PCBs in schools is of particular concern given evidence suggesting that PCBs are developmental toxins. JF - Environmental Health Perspectives AU - Herrick, Robert F AU - McClean, Michael D AU - Meeker, John D AU - Baxter, Lisa K AU - Weymouth, George A AD - super(1)Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1051 EP - 1053 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts KW - Ventilation KW - Contamination KW - Toxic substances KW - Dust KW - USA, Massachusetts, Boston KW - schools KW - Waste disposal KW - PCB compounds KW - public buildings KW - Construction materials KW - Buildings KW - Toxins KW - EPA KW - Indoor environments KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21348554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=An+Unrecognized+Source+of+PCB+Contamination+in+Schools+and+Other+Buildings&rft.au=Herrick%2C+Robert+F%3BMcClean%2C+Michael+D%3BMeeker%2C+John+D%3BBaxter%2C+Lisa+K%3BWeymouth%2C+George+A&rft.aulast=Herrick&rft.aufirst=Robert&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1051&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6912 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA, Massachusetts, Boston; PCB compounds; Buildings; EPA; schools; public buildings; Toxic substances; Toxins; Indoor environments; Contamination; Construction materials; Ventilation; Dust; Waste disposal DO - http://dx.doi.org/10.1289/ehp.6912 ER - TY - JOUR T1 - Temporal constraints on Palaeoproterozoic eclogite formation and exhumation (Usagaran Orogen, Tanzania) AN - 21343041; 5984601 AB - In-situ rock suites that preserve assemblages consistent with metamorphism to eclogite-facies conditions are absent from the Archaean. Their Palaeoproterozoic appearance is one of the markers of the onset of tectonic processes similar to those seen in the Phanerozoic Earth. We report new U-Pb Secondary Ion Mass Spectrometry (SIMS) zircon data from the oldest known eclogites (the ~2.0 Ga Usagaran eclogites, Tanzania) that constrain the timing of high-grade metamorphism, deformation and exhumation of these eclogites and constrain the speed of these processes at this critical period in Earth history. Direct dating of metamorphic zircon from mafic eclogites, and isostructurally recrystallised zircon rims from pelites and felsic gneisses indicates that high- grade metamorphism occurred at 1999.1+/-1.1 Ma. The rocks were quickly cooled and exhumed at rates of ~25 C/Ma and 0.06-0.22 GPa/Ma, respectively, at least in part, by amphibolite-facies sinistral transpression constrained by a 1991+/-2 Ma pegmatite dyke that crosscuts foliation. Detrital zircons in metasedimentary gneiss protoliths were dominantly derived from two sources: (1) the Tanzanian craton, and (2) a 2400-2640 Ma source region that is compatible with a belt of reworked Archaean and Palaeoproterozoic rocks that lie in the East African Orogen. JF - Earth and Planetary Science Letters AU - Collins, A S AU - Reddy, S M AU - Buchan, C AU - Mruma, A AD - Tectonics SRC, Department of Applied Geology, Curtin University of Technology, GPO Box U1987, Perth WA 6845, Australia, acollins@tsrc.uwa.edu.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 175 EP - 192 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 224 IS - 1-2 SN - 0012-821X, 0012-821X KW - Microbiology Abstracts B: Bacteriology KW - eclogite KW - Palaeoproterozoic KW - SHRIMP KW - U-Pb isotopes KW - Usagaran Orogen KW - exhumation KW - zircon KW - dating deformation KW - Tanzania KW - geochronology KW - Data processing KW - Dating KW - Critical period KW - Mass spectroscopy KW - J 02490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21343041?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Earth+and+Planetary+Science+Letters&rft.atitle=Temporal+constraints+on+Palaeoproterozoic+eclogite+formation+and+exhumation+%28Usagaran+Orogen%2C+Tanzania%29&rft.au=Collins%2C+A+S%3BReddy%2C+S+M%3BBuchan%2C+C%3BMruma%2C+A&rft.aulast=Collins&rft.aufirst=A&rft.date=2004-07-01&rft.volume=224&rft.issue=1-2&rft.spage=175&rft.isbn=&rft.btitle=&rft.title=Earth+and+Planetary+Science+Letters&rft.issn=0012821X&rft_id=info:doi/10.1016%2Fj.epsl.2004.04.027 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Data processing; Dating; Critical period; Mass spectroscopy DO - http://dx.doi.org/10.1016/j.epsl.2004.04.027 ER - TY - JOUR T1 - Book Review. Albert R. Roberts and Kenneth R. Yeager (Eds). Evidence-Based Practice Manual: Research and Outcome Measures in Health and Human Services. New York: Oxford University Press, 2004. 1092 pp. ISBN 0-19-516500-4, $89.50 (hardback). AN - 204718833 JF - Brief Treatment and Crisis Intervention AU - Congress, Elaine P Y1 - 2004///Summer PY - 2004 DA - Summer 2004 SP - 195 CY - Cary PB - Oxford Publishing Limited(England) VL - 4 IS - 2 SN - 14743310 KW - Medical Sciences--Psychiatry And Neurology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/204718833?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthcompleteshell&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Brief+Treatment+and+Crisis+Intervention&rft.atitle=Book+Review.+Albert+R.+Roberts+and+Kenneth+R.+Yeager+%28Eds%29.+Evidence-Based+Practice+Manual%3A+Research+and+Outcome+Measures+in+Health+and+Human+Services.+New+York%3A+Oxford+University+Press%2C+2004.+1092+pp.+ISBN+0-19-516500-4%2C+%2489.50+%28hardback%29.&rft.au=Congress%2C+Elaine+P&rft.aulast=Congress&rft.aufirst=Elaine&rft.date=2004-07-01&rft.volume=4&rft.issue=2&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Brief+Treatment+and+Crisis+Intervention&rft.issn=14743310&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright Oxford University Press(England) Summer 2004 N1 - Last updated - 2010-06-07 ER - TY - JOUR T1 - Sinorhizobium meliloti metabolism in the root nodule: A proteomic perspective AN - 18041715; 5989534 AB - The proteome of the model symbiotic bacterium, Sinorhizobium meliloti was examined to determine the enzymatic reactions and cell processes that occur when S. meliloti occupies the root nodules of Medicago truncatula and Melilotus alba. The proteomes of the nodule bacteria were compared to that of S. meliloti grown under laboratory cultured conditions as an additional control. All the detectable protein spots on the two-dimensional (2-D) gels between pH 4-7 were analyzed. In total, the identity of proteins in 1545 spots from 2-D gels was determined using peptide mass fingerprinting. There were clear differences in the proteome of nodule bacteria and cultured bacteria and putative nodule-specific and nodule suppressed proteins were identified. The data were analyzed using metabolic pathway prediction programs and used to review the biochemical and genetic studies that had been done previously on S. meliloti over several decades. There was a broad congruency between the proteomic and biochemical data when the overall pathways of central carbon and nitrogen metabolism were considered. A selective suite of ABC-type transporters was present in nodule bacteria that were biased towards the transport of amino acids and inorganic ions (P and Fe) suggesting that a highly specialized nutrient exchange was occurring between the nodule bacteria and the host. Proteins prominent in nodule bacteria were those involved in the pathways for vitamin synthesis and stress-related processes (chaperoning, heat shock, detoxification of reactive oxygen species, regulation of stress and osmo-regulation). Some of these proteins were found only in nodule bacteria. These results show the extent of the shift in metabolism that occurs when S. meliloti invades legume plants and establishes a nitrogen fixing symbiosis. JF - Proteomics AU - Djordjevic, MA AD - ARC Centre of Excellence for Integrative Legume Research, Genomic Interactions Group, Research School of Biological Sciences, Australian National University, GPO Box 475, Canberra, ACT, 2601, Australia, michael@rsbs.anu.edu.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1859 EP - 1872 VL - 4 IS - 7 SN - 1615-9853, 1615-9853 KW - Microbiology Abstracts B: Bacteriology KW - proteomes KW - Symbionts KW - Nitrogen fixation KW - Rhizosphere KW - Roots KW - Sinorhizobium meliloti KW - Medicago truncatula KW - Nodules KW - J 02901:Soil and plants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18041715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proteomics&rft.atitle=Sinorhizobium+meliloti+metabolism+in+the+root+nodule%3A+A+proteomic+perspective&rft.au=Djordjevic%2C+MA&rft.aulast=Djordjevic&rft.aufirst=MA&rft.date=2004-07-01&rft.volume=4&rft.issue=7&rft.spage=1859&rft.isbn=&rft.btitle=&rft.title=Proteomics&rft.issn=16159853&rft_id=info:doi/10.1002%2Fpmic.200300802 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Sinorhizobium meliloti; Medicago truncatula; Nodules; Rhizosphere; Roots; proteomes; Symbionts; Nitrogen fixation DO - http://dx.doi.org/10.1002/pmic.200300802 ER - TY - JOUR T1 - Protein extraction from mature rice leaves for two-dimensional gel electrophoresis and its application in proteome analysis AN - 17752315; 5989537 AB - Sample preparation is crucial for extraction and higher resolution of proteins by two-dimensional gel electrophoresis (2-DE). In this study, we present an efficient protocol to extract proteins from mature rice leaves by minimizing the presence of nonprotein contaminants and by maximizing contact between the sample and extraction buffer. A combination of chemical and physical processes remarkably improved protein extraction for 2-DE. The efficiency of this protocol was demonstrated by comparison of the rice proteome at two developmental stages. JF - Proteomics AU - Islam, N AU - Lonsdale, M AU - Upadhyaya, N M AU - Higgins, T J AU - Hirano, H AU - Akhurst, R AD - CSIRO, Entomology, GPO Box 1700, Canberra ACT 2601, Australia, naz.islam@csiro.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1903 EP - 1908 VL - 4 IS - 7 SN - 1615-9853, 1615-9853 KW - Rice KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - Buffers KW - Leaves KW - Developmental stages KW - Oryza sativa KW - proteomics KW - Contaminants KW - Gel electrophoresis KW - W2 32250:Others KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17752315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proteomics&rft.atitle=Protein+extraction+from+mature+rice+leaves+for+two-dimensional+gel+electrophoresis+and+its+application+in+proteome+analysis&rft.au=Islam%2C+N%3BLonsdale%2C+M%3BUpadhyaya%2C+N+M%3BHiggins%2C+T+J%3BHirano%2C+H%3BAkhurst%2C+R&rft.aulast=Islam&rft.aufirst=N&rft.date=2004-07-01&rft.volume=4&rft.issue=7&rft.spage=1903&rft.isbn=&rft.btitle=&rft.title=Proteomics&rft.issn=16159853&rft_id=info:doi/10.1002%2Fpmic.200300816 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Oryza sativa; Gel electrophoresis; Leaves; Contaminants; proteomics; Developmental stages; Buffers DO - http://dx.doi.org/10.1002/pmic.200300816 ER - TY - JOUR T1 - Two major classes of target site insensitivity mutations confer resistance to organophosphate and carbamate insecticides AN - 17593369; 5962355 AB - Interspecific comparisons of bioassay and biochemical data suggest two major patterns of target site resistance to carbamates and organophosphates. Pattern I resistance, which is generally more effective for carbamates, has been shown in two sub-species of mosquitoes to be due to a particular Gly-Ser mutation in the oxyanion hole within the active site of one of their two acetylcholinesterase enzymes. Intriguingly, different substitutions at the equivalent site confer organophosphate hydrolytic ability on other esterases responsible for metabolic resistance in some other species. In the case of the aphid, Myzus persicae, Pattern I resistance is due to a Ser-Phe mutation in the vicinity of the acyl pocket of acetylcholinesterase. Pattern II resistance is at least as effective for organophosphates as it is for carbamates and may even be specific to organophosphates in some cases. Molecular studies on this pattern of resistance in three higher Diptera show that it is due to changes that constrict the acetylcholinesterase active site gorge and limit binding of the insecticide to the catalytic residues at the base of the gorge. One case of Pattern II resistance in the mosquito, Culex tritaeniorhynchus, involves the same site near the acyl pocket of acetylcholinesterase, albeit a different substitution, as that involved in Pattern I resistance in M. persicae. JF - Pesticide Biochemistry and Physiology AU - Russell, R J AU - Claudianos, C AU - Campbell, P M AU - Horne, I AU - Sutherland, T D AU - Oakeshott, JG AD - CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia, Robyn.Russell@csiro.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 84 EP - 93 PB - Elsevier Inc. VL - 79 IS - 3 SN - 0048-3575, 0048-3575 KW - Aphids KW - Homoptera KW - ASFA 3: Aquatic Pollution & Environmental Quality; Entomology Abstracts KW - Z 05215:Mutation KW - Q5 01504:Effects on organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17593369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pesticide+Biochemistry+and+Physiology&rft.atitle=Two+major+classes+of+target+site+insensitivity+mutations+confer+resistance+to+organophosphate+and+carbamate+insecticides&rft.au=Russell%2C+R+J%3BClaudianos%2C+C%3BCampbell%2C+P+M%3BHorne%2C+I%3BSutherland%2C+T+D%3BOakeshott%2C+JG&rft.aulast=Russell&rft.aufirst=R&rft.date=2004-07-01&rft.volume=79&rft.issue=3&rft.spage=84&rft.isbn=&rft.btitle=&rft.title=Pesticide+Biochemistry+and+Physiology&rft.issn=00483575&rft_id=info:doi/10.1016%2Fj.pestbp.2004.03.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.pestbp.2004.03.002 ER - TY - JOUR T1 - Effect Measures in Prevalence Studies AN - 14706642; 10665547 AB - The relationship between indices and prevalence studies is reviewed briefly, and the relative merits of using prevalence odds ratios and prevalence ratios are elucidated and discussed, arguing that prevalence odds ratios should continue to be one of the standard methods for analyzing such studies. Three arguments are offered for use of the prevalence odds ratio: it estimates the incidence rate ratio with fewer assumptions than required for the prevalence ratio; it can be estimated using the same methods as for the odds ratio in casecontrol studies; and it provides practical, analytical, and theoretical consistency between analyses of a prevalence study and those of a prevalence casecontrol study. JF - Environmental Health Perspectives AU - Pearce, Neil Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1047 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - DISEASES AND DISORDERS KW - PUBLIC HEALTH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706642?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+Measures+in+Prevalence+Studies&rft.au=Pearce%2C+Neil&rft.aulast=Pearce&rft.aufirst=Neil&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1047&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; DISEASES AND DISORDERS; PUBLIC HEALTH ER - TY - JOUR T1 - Biomarkers in Maternal and Newborn Blood Indicate Heightened Fetal Susceptibility to Procarcinogenic DNA Damage AN - 14706171; 10665562 AB - Pregnant minority women living in New York City were studied to explore the relationship between maternal exposure to PAHs and environmental tobacco smoke, and fetal susceptibility to procarcinogenic DNA damage. Carcinogenic DNA adducts and cotinine were compared in paired blood samples collected from mothers and newborns. The levels of DNA damage from PAHs in white blood cells were higher than expected in newborns compared with the paired mothers. Detectable adducts were found in 34% of newborns whose mothers had nondetectable levels of adducts, while 30% of mothers with detectable adducts had newborns with nondetectable levels of adducts. While levels of adducts in paired newbornmaternal samples were modestly but significantly correlated, as were cotinine levels, DNA adducts were not correlated significantly with cotinine in either maternal or newborn samples. Environmental tobacco smoke was correlated significantly with cotinine in both maternal and newborn samples, but dietary PAHs and environmental tobacco smoke were not associated significantly with adducts, nor were adducts correlated with PAHs in air monitored during pregnancy. JF - Environmental Health Perspectives AU - Perera, Frederica P AU - Tang, Deliang AU - Tu, Yi-Hsuan AU - Cruz, Linda Ali AU - Borjas, Mejico AU - Bernert, Tom AU - Whyatt, Robin M Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1133 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MINORITIES KW - SUSCEPTIBILITY KW - CIGARETTE SMOKE KW - POLYCYCLIC AROMATIC HYDROCARBON KW - CARCINOGENIC AGENTS KW - REPRODUCTION, HUMAN KW - DNA KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706171?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biomarkers+in+Maternal+and+Newborn+Blood+Indicate+Heightened+Fetal+Susceptibility+to+Procarcinogenic+DNA+Damage&rft.au=Perera%2C+Frederica+P%3BTang%2C+Deliang%3BTu%2C+Yi-Hsuan%3BCruz%2C+Linda+Ali%3BBorjas%2C+Mejico%3BBernert%2C+Tom%3BWhyatt%2C+Robin+M&rft.aulast=Perera&rft.aufirst=Frederica&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1133&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MINORITIES; CARCINOGENIC AGENTS; SUSCEPTIBILITY; REPRODUCTION, HUMAN; DNA; CIGARETTE SMOKE; NEW YORK CITY; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Survivorship Patterns of Larval Amphibians Exposed to Low Concentrations of Atrazine AN - 14706108; 10665549 AB - Tadpoles of four species of frogs were exposed at early and late developmental stages to atrazine concentrations of 3, 30, or 100 ppb, and effects on survival were determined and compared. The species included: spring peepers Pseudacris crucifer, American toads Bufo americanus, green frogs Rana clamitans, and wood frogs R. sylvatica. Exposures lasted for approximately 30 d. Generally, animals exposed to the low atrazine concentration died sooner than animals exposed to the medium or high concentrations, and the pattern was similar for all species except for late American toads. JF - Environmental Health Perspectives AU - Storrs, Sara I AU - Kiesecker, Joseph M Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1054 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AGE COMPARISONS KW - TOADS KW - DOSE RESPONSE PROFILES KW - SPECIES COMPARISONS KW - ATRAZINE KW - MORTALITY PATTERNS KW - FROGS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706108?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Survivorship+Patterns+of+Larval+Amphibians+Exposed+to+Low+Concentrations+of+Atrazine&rft.au=Storrs%2C+Sara+I%3BKiesecker%2C+Joseph+M&rft.aulast=Storrs&rft.aufirst=Sara&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1054&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; TOADS; SPECIES COMPARISONS; ATRAZINE; MORTALITY PATTERNS; AGE COMPARISONS; FROGS ER - TY - JOUR T1 - Manufactured Nanomaterials (Fullerenes, C sub(60)) Induce Oxidative Stress in the Brain of Juvenile Largemouth Bass AN - 14704212; 10665550 AB - Nanomaterials are defined as materials with at least one dimension in the 1- to 100-nm range, and fullerenes constitute one type of manufactured nanoparticle. In this study, juvenile largemouth bass Micropterus salmoides were exposed to uncoated 99.5% pure fullerenes that were water-solubilized using standard methods, and effects on oxidative stress were assessed. After 48 h of exposure to 0.5-ppm aqueous uncoated fullerenes, lipid peroxidation was elevated significantly in brains, and glutathione levels were depleted in gills. JF - Environmental Health Perspectives AU - Oberdorster, Eva Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1058 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - ANTIOXIDANTS KW - OXIDANT STRESS KW - BASS KW - GLUTATHIONE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704212?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Manufactured+Nanomaterials+%28Fullerenes%2C+C+sub%2860%29%29+Induce+Oxidative+Stress+in+the+Brain+of+Juvenile+Largemouth+Bass&rft.au=Oberdorster%2C+Eva&rft.aulast=Oberdorster&rft.aufirst=Eva&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1058&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 17 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; ANTIOXIDANTS; OXIDANT STRESS; BASS; GLUTATHIONE ER - TY - JOUR T1 - Prenatal Insecticide Exposure and Birth Weight and Length Among an Urban Minority Cohort AN - 14703731; 10665561 AB - Women who were part of an ongoing prospective cohort study of minority mothers and their newborns being conducted by the Columbia Center for Children's Environmental Health in New York City were studied to assess the relationship between prenatal insecticide exposure and birth weight and length. The effects of exposure were examined in the total cohort and again after stratifying on year of delivery. The women were enrolled between 1998 and 2002. Demographic data were obtained via questionnaire, and prenatal personal ambient-air samples were collected and analyzed. In addition, a sample of umbilical cord blood was collected, and measures of fetal growth were obtained from medical records after delivery. Results showed an inverse relationship between chlorpyrifos levels in umbilical cord plasma and birth weight and length, especially among newborns with the highest 25% of exposure levels. The data also suggested that prenatal diazinon exposure may have contributed to fetal growth deficits, and when cumulative risk assessment was conducted, the magnitude of the effect of chlorpyrifos and diazinon on birth weight was greater than that for chlorpyrifos alone. The association between insecticide exposure and fetal growth was found only when biomarkers were used as a dosimeter of prenatal exposure and not when environmental measures were used. JF - Environmental Health Perspectives AU - Whyatt, Robin M AU - Rauh, Virginia AU - Barr, Dana B AU - Camann, David E AU - Andrews, Howard F AU - Garfinkel, Robin AU - Hoepner, Lori A Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1125 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DIAZINON KW - MINORITIES KW - INSECTICIDE EXPOSURE KW - REPRODUCTION, HUMAN KW - CHLORPYRIFOS KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prenatal+Insecticide+Exposure+and+Birth+Weight+and+Length+Among+an+Urban+Minority+Cohort&rft.au=Whyatt%2C+Robin+M%3BRauh%2C+Virginia%3BBarr%2C+Dana+B%3BCamann%2C+David+E%3BAndrews%2C+Howard+F%3BGarfinkel%2C+Robin%3BHoepner%2C+Lori+A&rft.aulast=Whyatt&rft.aufirst=Robin&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1125&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DIAZINON; MINORITIES; INSECTICIDE EXPOSURE; REPRODUCTION, HUMAN; CHLORPYRIFOS; NEW YORK CITY ER - TY - JOUR T1 - Community-Based Randomized Double-Blind Study of Gastrointestinal Effects and Copper Exposure in Drinking Water AN - 14703668; 10665552 JF - Environmental Health Perspectives AU - Araya, Magdalena AU - Olivares, Manuel AU - Pizarro, Fernando AU - Llanos, Adolfo AU - Figueroa, Guillermo AU - Uauy, Ricardo Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1068 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHILE KW - DOSE RESPONSE PROFILES KW - COPPER KW - PHYSIOLOGICAL EFFECTS, HUMAN KW - WATER, DRINKING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Community-Based+Randomized+Double-Blind+Study+of+Gastrointestinal+Effects+and+Copper+Exposure+in+Drinking+Water&rft.au=Araya%2C+Magdalena%3BOlivares%2C+Manuel%3BPizarro%2C+Fernando%3BLlanos%2C+Adolfo%3BFigueroa%2C+Guillermo%3BUauy%2C+Ricardo&rft.aulast=Araya&rft.aufirst=Magdalena&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1068&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHILE; DOSE RESPONSE PROFILES; PHYSIOLOGICAL EFFECTS, HUMAN; COPPER; WATER, DRINKING ER - TY - JOUR T1 - Blood Lead Secular Trend in a Cohort of Children in Mexico City (19872002) AN - 14703485; 10665559 AB - Children in Mexico City born between 1987 and 1992 were monitored for their blood lead levels every six months for the first 10 yr of their lives. Air Pb data were collected from three monitoring stations throughout the study, and socioeconomic status was computed based on the education and occupation of the head of the household and total family income. Residence in the highest air Pb zone was associated significantly with higher lifetime blood Pb concentrations. Blood Pb levels were also associated with socioeconomic status, the age of the child at the time of Pb lead measurement, the year in which the child was born, and the family use of Pb-glazed ceramics. JF - Environmental Health Perspectives AU - Schnaas, Lourdes AU - Rothenberg, Stephen J AU - Flores, Maria-Fernanda AU - Martinez, Sandra AU - Hernandez, Carmen AU - Osorio, Erica AU - Perroni, Estela Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1110 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - SPATIAL COMPARISONS KW - AGE COMPARISONS KW - URBAN ATMOSPHERE KW - SOCIOECONOMICS KW - MEXICO KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703485?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Blood+Lead+Secular+Trend+in+a+Cohort+of+Children+in+Mexico+City+%281987%26lt%3BND%26gt%3B2002%29&rft.au=Schnaas%2C+Lourdes%3BRothenberg%2C+Stephen+J%3BFlores%2C+Maria-Fernanda%3BMartinez%2C+Sandra%3BHernandez%2C+Carmen%3BOsorio%2C+Erica%3BPerroni%2C+Estela&rft.aulast=Schnaas&rft.aufirst=Lourdes&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOCIOECONOMICS; MEXICO; BLOOD LEAD LEVEL; SPATIAL COMPARISONS; AGE COMPARISONS; URBAN ATMOSPHERE ER - TY - JOUR T1 - Associations Between Organochlorine Contaminant Concentrations and Clinical Health Parameters in Loggerhead Sea Turtles from North Carolina, USA AN - 14703411; 10665553 AB - In 48 live, free-ranging, juvenile loggerhead sea turtles Caretta caretta collected as bycatch in Core Sound, NC, the association between indicators of health and organochlorine concentrations was explored. Almost all of the contaminants, which included chlordanes, dieldrin, mirex, DDTs, PCBs, and TCDD-like PCBs, were intercorrelated in terms of concentration. All of the major groups of contaminants were correlated with total white blood cell counts, and chlordanes and mirex were correlated significantly with fewer lymphocytes. Total DDTs and total organochlorines in both blood and adipose tissue and total PCBs in adipose tissue correlated positively with eosinophils. Body condition was correlated negative with dieldrin in blood, and glucose concentrations were correlated negatively with adipose concentrations of dieldrin and total DDTs. Blood urea nitrogen concentrations were correlated positively with concentrations of most organochlorine classes measured in blood. Aspartate aminotransferase activity was correlated positively with most of the organochlorine compounds in blood and adipose tissue, while alkaline phosphatase activity was correlated negatively with mirex concentrations in blood and adipose tissue and with TCDD-like PCBs in blood, and gamma -glutamyl transferase activity was correlated negatively with concentrations of dieldrin in blood. JF - Environmental Health Perspectives AU - Keller, Jennifer M AU - Kucklick, John R AU - Stamper, MAndrew AU - Harms, Craig A AU - McClellan-Green, Patricia D Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1074 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PESTICIDE RESIDUES KW - ENZYME ACTIVITY KW - NORTH CAROLINA KW - ORGANOCHLORINE PESTICIDES KW - BLOOD ANALYSIS KW - TURTLES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Associations+Between+Organochlorine+Contaminant+Concentrations+and+Clinical+Health+Parameters+in+Loggerhead+Sea+Turtles+from+North+Carolina%2C+USA&rft.au=Keller%2C+Jennifer+M%3BKucklick%2C+John+R%3BStamper%2C+MAndrew%3BHarms%2C+Craig+A%3BMcClellan-Green%2C+Patricia+D&rft.aulast=Keller&rft.aufirst=Jennifer&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1074&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; PESTICIDE RESIDUES; ENZYME ACTIVITY; TURTLES; NORTH CAROLINA; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Adverse Health Effects of Chronic Exposure to Low-Level Cadmium in Foodstuffs and Cigarette Smoke AN - 14702772; 10665557 AB - Clinically relevant outcomes of chronic exposure to environmental cadmium via food and cigarette smoke are highlighted, including renal failure, bone fragility, reproductive outcomes, and human cancers. Data gleaned from a number of studies conducted in different countries are cited in the discussion. Persistence of the metal in the environment and in humans will require a long-term approach to minimizing exposure, one part of which needs to be international food legislation that sets a maximum Cd level in agricultural products. JF - Environmental Health Perspectives AU - Satarug, Soisungwan AU - Moore, Michael R Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1099 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DIET KW - CADMIUM KW - BIOACCUMULATION, HUMAN KW - FOOD CONTAMINATION KW - PHYSIOLOGICAL EFFECTS, HUMAN KW - CARCINOGENIC AGENTS KW - DISEASES AND DISORDERS KW - LEGISLATION, INTERNATIONAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702772?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Adverse+Health+Effects+of+Chronic+Exposure+to+Low-Level+Cadmium+in+Foodstuffs+and+Cigarette+Smoke&rft.au=Satarug%2C+Soisungwan%3BMoore%2C+Michael+R&rft.aulast=Satarug&rft.aufirst=Soisungwan&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1099&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 54 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; CARCINOGENIC AGENTS; PHYSIOLOGICAL EFFECTS, HUMAN; LEGISLATION, INTERNATIONAL; DIET; CADMIUM; BIOACCUMULATION, HUMAN; FOOD CONTAMINATION ER - TY - JOUR T1 - Nutritional Factors and Susceptibility to Arsenic-Caused Skin Lesions in West Bengal, India AN - 14702415; 10665558 JF - Environmental Health Perspectives AU - Mitra, Soma R AU - Guha Mazumder, DN AU - Basu, Arindam AU - Block, Gladys AU - Haque, Reina AU - Samanta, Sambit AU - Ghosh, Nilima Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1104 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DEFICIENCY DISEASES KW - ARSENIC KW - NUTRITION KW - INDIA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Nutritional+Factors+and+Susceptibility+to+Arsenic-Caused+Skin+Lesions+in+West+Bengal%2C+India&rft.au=Mitra%2C+Soma+R%3BGuha+Mazumder%2C+DN%3BBasu%2C+Arindam%3BBlock%2C+Gladys%3BHaque%2C+Reina%3BSamanta%2C+Sambit%3BGhosh%2C+Nilima&rft.aulast=Mitra&rft.aufirst=Soma&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1104&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DEFICIENCY DISEASES; ARSENIC; NUTRITION; INDIA ER - TY - JOUR T1 - Association of in Utero Organophosphate Pesticide Exposure and Fetal Growth and Length of Gestation in an Agricultural Populations AN - 14702413; 10665560 AB - In an agricultural community in the Salinas Valley, CA, exposure of pregnant women to organophosphate pesticides was examined in relation to fetal growth and length of gestation. After screening, 488 pregnant women were included and were interviewed twice during pregnancy and then shortly after delivery. Exposure to organophosphate pesticides was assessed by measuring specific metabolites in maternal urine during pregnancy and by measuring chloinesterase (ChE) in whole blood and butyryl ChE in plasma of mothers during pregnancy and at delivery and in umbilical cord blood. A decrease in gestational duration was found to be associated clearly with two measures of in utero pesticide exposure: levels of metabolites of dimethyl phosphate pesticide compounds, and whole-blood ChE. No adverse relationship was found, however, between fetal growth and in utero organophosphate pesticide exposure. JF - Environmental Health Perspectives AU - Eskenazi, Brenda AU - Harley, Kim AU - Bradman, Asa AU - Weltzien, Erin AU - Jewell, Nicholas P AU - Barr, Dana B AU - Furlong, Clement E Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1116 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHOLINESTERASE KW - CALIFORNIA KW - ORGANOPHOSPHATE PESTICIDES KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+of+in+Utero+Organophosphate+Pesticide+Exposure+and+Fetal+Growth+and+Length+of+Gestation+in+an+Agricultural+Populations&rft.au=Eskenazi%2C+Brenda%3BHarley%2C+Kim%3BBradman%2C+Asa%3BWeltzien%2C+Erin%3BJewell%2C+Nicholas+P%3BBarr%2C+Dana+B%3BFurlong%2C+Clement+E&rft.aulast=Eskenazi&rft.aufirst=Brenda&rft.date=2004-07-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=9781321249545&rft.btitle=&rft.title=Passages+and+Screens%3A+Media+Technologies+in+Texts+by+Henry+James%2C+Clara+Smith%2C+Theodora+Bosanquet%2C+Mina+Loy%2C+and+Kenneth+Fearing&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CALIFORNIA; BLOOD ANALYSIS; ORGANOPHOSPHATE PESTICIDES; REPRODUCTION, HUMAN; CHOLINESTERASE; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Personal Exposure to Submicrometer Particles and Heart Rate Variability in Human Subjects AN - 14702399; 10665551 AB - Personal exposure to submicrometer particles with a size range of 0.021.0 mu m and heart-rate variability were measured in nine young adults and ten elderly patients with lung-function impairments. Personal monitoring was performed for each subject using a P-TRAK Ultrafine Particle Counter, and continuous ambulatory electrocardiographic monitoring was conducted. The main effects of exposure to submicrometer particles were decreases in both the time-domain indices and frequency-domain indices that were consistent with effects caused by PM sub(2.5). Exposure to submicrometer particles appeared to exert similar effects on heart-rate variability in both young adults and elderly patients. The elderly panel had grater decreases in frequency-domain heart-rate variability indices in response to exposures than did the young adult panel, and only the elderly panel exhibited a time-course effect of exposure on frequency-domain heart-rate variability indices. JF - Environmental Health Perspectives AU - Chan, Chang-Chuan AU - Chuang, Kai-Jen AU - Shiao, Guang-Ming AU - Lin, Lian-Yu Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1063 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CARDIOVASCULAR EFFECTS KW - AGE COMPARISONS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702399?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Personal+Exposure+to+Submicrometer+Particles+and+Heart+Rate+Variability+in+Human+Subjects&rft.au=Chan%2C+Chang-Chuan%3BChuang%2C+Kai-Jen%3BShiao%2C+Guang-Ming%3BLin%2C+Lian-Yu&rft.aulast=Chan&rft.aufirst=Chang-Chuan&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1063&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; CARDIOVASCULAR EFFECTS; AGE COMPARISONS; PARTICULATES ER - TY - JOUR T1 - Different Levels of Polybrominated Diphenyl Ethers (PBDEs) and Chlorinated Compounds in Breast Milk from Two U.K. Regions AN - 14702363; 10665555 AB - Breast-milk samples were collected from UK women in maternity wards in London and Lancaster, and levels of polybrominated diphenyl ethers (PBDEs) were measured and related to current and temporal PCB and organochlorine levels in the country. The total PBDE levels ranged 0.169.0 ng/g lipid, and PBDE-47 was the most abundant congener. Total PCB levels ranged 26530 ng/g lipid, and congeners 153, 138, and 180 dominated. The breast-milk samples originating from London tended to exhibit higher geometric mean levels for all contaminants, including organochlorine pesticides, compared with the Lancaster levels. All relevant concentration data are tabulated. JF - Environmental Health Perspectives AU - Kalantzi, Olga I AU - Martin, Francis L AU - Thomas, Gareth O AU - Alcock, Ruth E AU - Tang, Huiru R AU - Drury, Suzanne C AU - Carmichael, Paul L Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1085 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - BREAST MILK KW - BIOACCUMULATION, HUMAN KW - ORGANOCHLORINE PESTICIDES KW - AREA COMPARISONS KW - FLAME RETARDANTS KW - UNITED KINGDOM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Different+Levels+of+Polybrominated+Diphenyl+Ethers+%28PBDEs%29+and+Chlorinated+Compounds+in+Breast+Milk+from+Two+U.K.+Regions&rft.au=Kalantzi%2C+Olga+I%3BMartin%2C+Francis+L%3BThomas%2C+Gareth+O%3BAlcock%2C+Ruth+E%3BTang%2C+Huiru+R%3BDrury%2C+Suzanne+C%3BCarmichael%2C+Paul+L&rft.aulast=Kalantzi&rft.aufirst=Olga&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1085&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AREA COMPARISONS; POLYCHLORINATED BIPHENYLS; BREAST MILK; ORGANOCHLORINE PESTICIDES; FLAME RETARDANTS; BIOACCUMULATION, HUMAN; UNITED KINGDOM ER - TY - JOUR T1 - Unhealthy Landscapes: Policy Recommendations on Land Use Change and Infectious Disease Emergence AN - 14700494; 10665556 JF - Environmental Health Perspectives AU - Patz, Jonathan A AU - Daszak, Peter AU - Tabor, Gary M AU - Aguirre, AAlonso AU - Pearl, Mary AU - Epstein, Jon AU - Wolfe, Nathan D Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1092 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DISEASES AND DISORDERS KW - PUBLIC HEALTH KW - BIOLOGICAL CONTAMINATION KW - LAND USE PLANNING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700494?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Unhealthy+Landscapes%3A+Policy+Recommendations+on+Land+Use+Change+and+Infectious+Disease+Emergence&rft.au=Patz%2C+Jonathan+A%3BDaszak%2C+Peter%3BTabor%2C+Gary+M%3BAguirre%2C+AAlonso%3BPearl%2C+Mary%3BEpstein%2C+Jon%3BWolfe%2C+Nathan+D&rft.aulast=Patz&rft.aufirst=Jonathan&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1092&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; PUBLIC HEALTH; BIOLOGICAL CONTAMINATION; LAND USE PLANNING ER - TY - JOUR T1 - Associations Between Plasma DDE Levels and Immunologic Measures in African-American Farmers in North Carolina AN - 14700434; 10665554 AB - Data from a population of African-American farmers from North Carolina were used to examine the association between p,p'-DDE levels and the immunologic parameters, immunoglobulin A (IgA) and immunoglobulin G (IgG). Antinuclear antibodies were measured to assess the potential effect on autoimmunity. The study subjects consisted of male farmers or farmworkers greater than or equal to 18 yr of age with at least 2 yr of farmwork experience as an adult. An inverse association was found between levels of p,p'-DDE in blood and IgG, but no such association was found for IgA. The prevalence of antinuclear antibodies was elevated in the highest category of p,p'-DDE exposure, but the trend was not statistically significant. JF - Environmental Health Perspectives AU - Cooper, Glinda S AU - Martin, Stephen A AU - Longnecker, Matthew P AU - Sandler, Dale P AU - Germolec, Dori R Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1080 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AFRICAN-AMERICANS KW - DDE KW - NORTH CAROLINA KW - BIOACCUMULATION, HUMAN KW - IMMUNOTOXICITY KW - BLOOD ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Associations+Between+Plasma+DDE+Levels+and+Immunologic+Measures+in+African-American+Farmers+in+North+Carolina&rft.au=Haney%2C+Lindsay+J.&rft.aulast=Haney&rft.aufirst=Lindsay&rft.date=2014-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=9781339179308&rft.btitle=&rft.title=Performing+anxiety%3A+Masculinities+in+contemporary+Irish+literature+and+culture&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - IMMUNOTOXICITY; BLOOD ANALYSIS; AFRICAN-AMERICANS; DDE; NORTH CAROLINA; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Clean Air Act Issues in the 108th Congress AN - 14700737; 10666113 AB - Prominent air quality issues that have been of interest in the 108th Congress are examined. Multi-pollutant, or Clear Skies, legislation has been proposed to replace numerous existing Clean Air Act requirements with a national cap and trade program for sulfur dioxide, nitrogen oxides, and mercury. Legislation was also approved to study the New Source Review changes proposed and promulgated by EPA. Other topics covered include designation of nonattainment areas for the 8-h ozone standard, emission standards for small engines, and transportation conformity. JF - US Congressional Research Service Report IB10107 AU - McCarthy, James E Y1 - 2004/06/23/ PY - 2004 DA - 2004 Jun 23 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - SULFUR DIOXIDE KW - GASOLINE KW - TRANSPORTATION EMISSION CONTROL KW - AIR QUALITY STANDARDS, SOURCE KW - EPA, FEDERAL KW - CLEAN AIR ACT AMENDMENTS 90 KW - OZONE KW - FUEL ADDITIVES KW - POWER PLANT EMISSION CONTROL KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10107&rft.atitle=Clean+Air+Act+Issues+in+the+108th+Congress&rft.au=McCarthy%2C+James+E&rft.aulast=McCarthy&rft.aufirst=James&rft.date=2004-06-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10107&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-13589.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; GASOLINE; TRANSPORTATION EMISSION CONTROL; EPA, FEDERAL; AIR QUALITY STANDARDS, SOURCE; CLEAN AIR ACT AMENDMENTS 90; POWER PLANT EMISSION CONTROL; FUEL ADDITIVES; MERCURY; OZONE ER - TY - JOUR T1 - Climate Change Legislation in the 108th Congress AN - 14701971; 10666117 AB - Bills directly addressing climate change issues in the 108th Congress range from those focused primarily on climate change research to comprehensive emissions cap and trading programs for all six greenhouse gases. Additional bills focus on greenhouse gas reporting and registries, or on power plant carbon dioxide emissions. S.139 and S.1164 would direct research on historical evidence of climate change to develop climate models; others would promote research on political and technological options to reduce emissions. Some bills would establish greenhouse gas emission thresholds above which an entity must submit records of its emissions; others exclude farms from the reporting requirement. JF - US Congressional Research Service Report RL32055 AU - Yacobucci, Brent D AU - Powers, Kyna Y1 - 2004/06/09/ PY - 2004 DA - 2004 Jun 09 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - AIR QUALITY PROGRAMS KW - LEGISLATION, FEDERAL KW - POWER PLANT EMISSIONS KW - EMISSIONS TRADING KW - CLIMATE CHANGE KW - DATA REPORTING, MANDATORY KW - GREENHOUSE EFFECT KW - CARBON DIOXIDE KW - WEATHER MODIFICATION RESEARCH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14701971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+RL32055&rft.atitle=Climate+Change+Legislation+in+the+108th+Congress&rft.au=Yacobucci%2C+Brent+D%3BPowers%2C+Kyna&rft.aulast=Yacobucci&rft.aufirst=Brent&rft.date=2004-06-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+RL32055&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-13593.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GREENHOUSE EFFECT; AIR QUALITY PROGRAMS; LEGISLATION, FEDERAL; CARBON DIOXIDE; POWER PLANT EMISSIONS; WEATHER MODIFICATION RESEARCH; EMISSIONS TRADING; CLIMATE CHANGE; DATA REPORTING, MANDATORY ER - TY - JOUR T1 - Wildfire Protection in the 108th Congress AN - 14701267; 10666115 AB - Federal wildfire management funding increased dramatically after the severe 2000 fire season. In August 2002, President Bush proposed the Health Forests Initiative, intended to improve fire protection through fuel loads reduction. Much of the focus of the 108th Congress has been on the Healthy Forests Restoration Act of 2003, which encompasses many of the issues addressed in the Healthy Forests Initiative and also includes titles allowing grants to use biomass, provides watershed forestry assistance, and establishes private forest reserves. In May 2004, federal contracts for 33 large firefighting airtankers were cancelled over concerns about their airworthiness. JF - US Congressional Research Service Report IB10124 AU - Gorte, Ross W Y1 - 2004/06/03/ PY - 2004 DA - 2004 Jun 03 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - FOREST FIRE CONTROL KW - WILDFIRES KW - FOREST MANAGEMENT KW - FOREST DEVELOPMENT FINANCING KW - LAW, FEDERAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14701267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10124&rft.atitle=Wildfire+Protection+in+the+108th+Congress&rft.au=Gorte%2C+Ross+W&rft.aulast=Gorte&rft.aufirst=Ross&rft.date=2004-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10124&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-13591.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FOREST FIRE CONTROL; FOREST DEVELOPMENT FINANCING; FOREST MANAGEMENT; WILDFIRES; LAW, FEDERAL ER - TY - JOUR T1 - Aerodynamics, voice quality, and laryngeal image analysis of normal and pathologic voices. AN - 85391816; pmid-15167024 AB - The purpose of this review is to describe examinations of phonatory function and their relation to image analysis of the unilaterally immobile larynx. Special emphasis was placed on image analysis using three-dimensional endoscopic images produced from CT scans.Developments in modern image processing technique have led to the quantification of various aspects of vocal fold vibration. Stroboscopic images of the vocal fold were digitized and, subsequently, the glottal gap area, amplitude, and degree of bowing were analyzed quantitatively in relation to phonatory function. Vocal fold vibration was observed with the aid of videokymography, during which images from a single transverse line can be recorded. Successive line images were shown in real time on a monitor, with the time dimension displayed in the vertical direction. This system enabled the assessment of left-right asymmetries, open quotient, propagation of mucosal waves, and forth. Three-dimensional endoscopic images derived from multislice CT scans provided a novel method for evaluating morphologic characteristics of the laryngeal lumen in relation to phonatory function. The combination of three-dimensional endoscopy and coronal reconstructed images supplemented stroboscopic findings exemplified by differences in vertical position and thickness between the vocal folds.Depth information about the vocal fold as well as the presence of paradoxic movement of the affected vocal fold and overadduction of the healthy vocal fold during phonation should be taken into account when surgical intervention to improve hoarseness resulting from unilateral vocal fold immobility is performed. Phonatory function tests, videostroboscopy, and laryngeal image analysis are prerequisites to achieving this goal. JF - Current opinion in otolaryngology & head and neck surgery AU - Yumoto, Eiji AD - Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kumamoto University, Japan. yumoto@gpo.kumamoto-u.ac.jp Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 166 EP - 173 VL - 12 IS - 3 SN - 1068-9508, 1068-9508 KW - Index Medicus KW - National Library of Medicine KW - Humans KW - *Image Processing, Computer-Assisted KW - *Imaging, Three-Dimensional KW - Kymography KW - *Laryngoscopy KW - Phonation: physiology KW - Photic Stimulation KW - *Pulmonary Ventilation: physiology KW - Reference Values KW - *Tomography, X-Ray Computed KW - *User-Computer Interface KW - Video Recording KW - *Vocal Cord Paralysis: diagnosis KW - Vocal Cord Paralysis: physiopathology KW - Vocal Cords: physiopathology KW - *Voice Disorders: diagnosis KW - Voice Disorders: physiopathology KW - *Voice Quality: physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85391816?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+opinion+in+otolaryngology+%26+head+and+neck+surgery&rft.atitle=Aerodynamics%2C+voice+quality%2C+and+laryngeal+image+analysis+of+normal+and+pathologic+voices.&rft.au=Yumoto%2C+Eiji&rft.aulast=Yumoto&rft.aufirst=Eiji&rft.date=2004-06-01&rft.volume=12&rft.issue=3&rft.spage=166&rft.isbn=&rft.btitle=&rft.title=Current+opinion+in+otolaryngology+%26+head+and+neck+surgery&rft.issn=10689508&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - Expression, purification, and in vitro characterization of recombinant salmon insulin-like growth factor-II. AN - 71919334; 15135411 AB - The insulin-like growth factors, IGF-I and IGF-II, are single chain polypeptides, which are structurally related to proinsulin and promote proliferation and differentiation of cells in many vertebrate species. Previous attempts to produce recombinant salmon IGF-II (rsIGF-II) were compromised by low expression levels and co-purification of incorrectly cleaved protein with the authentic recombinant product. In this study, a gene containing the coding region for Atlantic salmon (Salmo salar) IGF-II was cloned into a modified pET32a expression vector and transformed into Escherichia coli BL21 trxB (DE3) cells. Upon growth and induction (with IPTG) of the transformant, recombinant salmon IGF-II (rsIGF-II) was expressed as an insoluble, 28kDa thioredoxin.sIGF-II fusion protein linked by a protease cleavage motif (trx.FAHY.sIGF-II) in inclusion bodies. The inclusion bodies were subsequently solubilized and the fusion protein was purified by Ni-affinity chromatography. Recombinant IGF-II (7.8kDa) was then released from the fusion partner using H64A subtilisin BPN' protease and purified by reversed-phase HPLC. Homogeneity of the final recombinant product was confirmed by N-terminal amino acid sequencing, ion-spray mass spectrometry, SDS-polyacrylamide gel electrophoresis, and analytical reversed-phase HPLC. The biological activity of rsIGF-II was demonstrated in cultured rat L6 myoblasts and was found to be approximately 9- and 5-fold less potent than recombinant human IGF-I and recombinant salmon IGF-I, respectively, a result similar to that demonstrated previously with other recombinant fish IGF-II's in non-homologous cell lines. JF - Protein expression and purification AU - Wilkinson, Ryan J AU - Elliott, Phillip AU - Carragher, John F AU - Francis, Geoffrey AD - School of Biological Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia. Ryan.Wilkinson@flinders.edu.au Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 334 EP - 343 VL - 35 IS - 2 SN - 1046-5928, 1046-5928 KW - DNA Primers KW - 0 KW - DNA, Recombinant KW - Recombinant Proteins KW - Insulin-Like Growth Factor II KW - 67763-97-7 KW - Index Medicus KW - Salmon KW - Animals KW - Electrophoresis, Polyacrylamide Gel KW - Fermentation KW - Escherichia coli -- genetics KW - Amino Acid Sequence KW - Recombinant Proteins -- genetics KW - Chromatography, High Pressure Liquid KW - Mutagenesis, Site-Directed KW - Recombinant Proteins -- isolation & purification KW - Base Sequence KW - Molecular Sequence Data KW - Insulin-Like Growth Factor II -- genetics KW - Insulin-Like Growth Factor II -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71919334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Protein+expression+and+purification&rft.atitle=Expression%2C+purification%2C+and+in+vitro+characterization+of+recombinant+salmon+insulin-like+growth+factor-II.&rft.au=Wilkinson%2C+Ryan+J%3BElliott%2C+Phillip%3BCarragher%2C+John+F%3BFrancis%2C+Geoffrey&rft.aulast=Wilkinson&rft.aufirst=Ryan&rft.date=2004-06-01&rft.volume=35&rft.issue=2&rft.spage=334&rft.isbn=&rft.btitle=&rft.title=Protein+expression+and+purification&rft.issn=10465928&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-03-29 N1 - Date created - 2004-05-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - RPRT T1 - How CBO Analyzes the Sources of Lenders' Interest Income on Guaranteed Student Loans. A CBO Report AN - 62013739; ED496555 AB - The Federal Family Education Loan (FFEL) program guarantees loans for postsecondary education to students and their parents at a limited interest rate. However, limiting borrowers' rates creates a danger that lenders will not be willing to participate in the program if their costs of financing and servicing the loans exceed the interest rates they may charge borrowers. To avoid that situation, the government generally supplements the borrowers' interest payments with additional quarterly payments to meet a target interest rate (or lender yield), which is an indicator of lenders' costs. The amounts that lenders receive from borrowers and the government depend on formulas specified in law and on the current level of two market interest rates, one used to calculate what borrowers pay and the other used to calculate the target yield for lenders, which determines what the government pays. This report describes the method the Congressional Budget Office (CBO) uses to estimate the sources of lenders' interest income on student and parent loans in the Federal Family Education Loan program. That method accounts for the likely values of future interest rates and specific program rules, including those for setting borrowers' rates and for calculating the government's supplemental payments. Includes the following appendix: Federal Student Loan Programs. (Contains 3 tables and 7 footnotes.) AU - Alsalam, Nabeel Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 20 PB - Congressional Budget Office. Ford House Office Building, 4th Floor, Second and D Streets SW, Washington, DC 20515-6925. KW - Family Education Loan program KW - ERIC, Resources in Education (RIE) KW - Postsecondary Education KW - Credit (Finance) KW - Federal Aid KW - Student Loan Programs KW - Government Role KW - Debt (Financial) KW - Income KW - Student Financial Aid KW - Costs KW - Computation KW - Federal Legislation KW - Public Agencies KW - Federal Programs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62013739?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - The Post-Apartheid Economy AN - 60713830; 200502554 AB - South Africa's postapartheid economy has been characterized by low growth & investment, & a rise in unemployment (at 30%, higher than any other middle income country). Government economic policy has stressed the encouragement of investment through deregulation, privatization, & fiscal restraint. However, the failure of this strategy to promote growth & create jobs points to the need for a more interventionist strategy, one in which government must do more to stimulate equitable growth. This proposition is highly contested. Nonetheless, in response to the crisis within the economy, the government has adopted limited reforms involving increased spending on basic social services & housing, greater emphasis on job creation & equity, a renewed stress on planning & coordination & greater support for cooperatives. Yet these new initiatives do not constitute a systematic plan for transforming the economy & more integrated policies are required to overcome dualism & stimulate job-creating growth. 11 Tables, 25 References. Adapted from the source document. JF - Review of African Political Economy AU - Makgetla, Neva Seidman AD - Congress South African Trade Unions neva@cosatu.org.za Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 263 EP - 281 VL - 31 IS - 100 SN - 0305-6244, 0305-6244 KW - State Intervention KW - Economic Conditions KW - Economic Development KW - Development Strategies KW - South Africa KW - Investment KW - Economic Policy KW - article KW - 9141: political economy; political economy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60713830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Review+of+African+Political+Economy&rft.atitle=The+Post-Apartheid+Economy&rft.au=Makgetla%2C+Neva+Seidman&rft.aulast=Makgetla&rft.aufirst=Neva&rft.date=2004-06-01&rft.volume=31&rft.issue=100&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=Review+of+African+Political+Economy&rft.issn=03056244&rft_id=info:doi/10.1080%2F0305624042000262284 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 29 N1 - Last updated - 2016-09-28 N1 - CODEN - RAPEF9 N1 - SubjectsTermNotLitGenreText - South Africa; Economic Conditions; Economic Development; Investment; State Intervention; Development Strategies; Economic Policy DO - http://dx.doi.org/10.1080/0305624042000262284 ER - TY - JOUR T1 - The Law: Must the Senate Take a Floor Vote on a Presidential Judicial Nominee? AN - 60699927; 200417121 AB - President George W. Bush has frequently urged the Senate to fulfill its constitutional duty & vote on his nominations to the federal courts. The administration argues that the Senate must hold up-or-down floor votes on all judicial nominees. Senate Democrats counter that the president is trying to short-circuit the procedural steps of the confirmation process. Currently, both sides are waging an ideological & institutional battle over the judicial confirmation process. This article analyzes the claim that the Senate must vote on all of the president's judicial nominees, & concludes that there is no basis for requiring that the Senate must hold mandatory confirmation votes for lower-court nominees. By tradition, the Senate generally takes floor votes for nominations to the Supreme Court. 36 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Sollenberger, Mitchel A AD - Congressional Research Service Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 420 EP - 436 VL - 34 IS - 2 SN - 0360-4918, 0360-4918 KW - nominations KW - Presidents KW - Roll Call KW - United States of America KW - Voting Behavior KW - Legislative Bodies KW - Judges KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60699927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=The+Law%3A+Must+the+Senate+Take+a+Floor+Vote+on+a+Presidential+Judicial+Nominee%3F&rft.au=Sollenberger%2C+Mitchel+A&rft.aulast=Sollenberger&rft.aufirst=Mitchel&rft.date=2004-06-01&rft.volume=34&rft.issue=2&rft.spage=420&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 36 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Legislative Bodies; Presidents; Judges; Voting Behavior; Roll Call; United States of America ER - TY - JOUR T1 - Environmental Index for Assessing Spatial Bias in Watershed Sampling Networks AN - 20604207; 6157005 AB - Bias in the design of stream-sampling networks can be a major cause of inaccurate characterization of ambient water quality. At the state level, sampling bias can impact a state's ability to produce an accurate assessment of the water quality of all state waters. At the federal level, this bias has hindered attempts by the U.S. Environmental Protection Agency (U.S. EPA) to produce nationwide assessments of water quality. Three types of bias commonly occur in water-quality assessments: design, analytical, and statistical. This paper focuses on "design bias," especially spatial-design bias, in stream monitoring networks. A geographic information system method is described to develop an environmental index to help recognize spatial design bias, and to prioritize areas (subwatersheds) for sampling. The environmental index, which is developed using data that are generally available from federal and state agencies, provides a means of differentiating the component parts of a watershed, its subwatersheds, in terms of two sets of features: natural landscape features and anthropogenic features or "stressors." Together, these features largely determine the variability of the quantity and quality of water discharged from watersheds. Subwatersheds with higher environmental-index values are expected to have more variable water quality over the course of a year than subwatersheds with lower index values. They are also expected to exert a greater influence on basinwide water quality. These properties of the index make it useful for (1) identifying the possible presence of spatial bias in existing watershed-sampling networks, (2) making sampling design decisions, and (3) aggregating data from subwatersheds into basinwide measures of water quality. Development and use of the index is demonstrated in a watershed in southern New Hampshire. JF - Journal of Environmental Engineering AU - Simcox, A C AU - Whittemore, R C AD - U.S. EPA Region 1 TMDL Coordinator, U.S. EPA, 1 Congress St., Ste. 1100 (CWQ), Boston, MA 02114, USA Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 622 EP - 630 VL - 130 IS - 6 SN - 0733-9372, 0733-9372 KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Water Resources Abstracts KW - water quality KW - Pollution monitoring KW - Variability KW - Remote sensing KW - Anthropogenic factors KW - Water quality KW - Watersheds KW - Streams KW - Assessments KW - Networks KW - Sampling KW - USA, New Hampshire KW - Geographical Information Systems KW - Environmental assessment KW - Landscape KW - Water Quality KW - Environmental Protection KW - Environmental protection KW - EPA KW - Geographic information systems KW - Monitoring KW - P 2000:FRESHWATER POLLUTION KW - SW 3010:Identification of pollutants KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - Q5 08522:Protective measures and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20604207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Engineering&rft.atitle=Environmental+Index+for+Assessing+Spatial+Bias+in+Watershed+Sampling+Networks&rft.au=Simcox%2C+A+C%3BWhittemore%2C+R+C&rft.aulast=Simcox&rft.aufirst=A&rft.date=2004-06-01&rft.volume=130&rft.issue=6&rft.spage=622&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Engineering&rft.issn=07339372&rft_id=info:doi/10.1061%2F%28ASCE%290733-9372%282004%29130%3A6%28622%29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-08-01 N1 - SuppNotes - Special Issue: Quantitative Approaches to the Determination of Total Maximum Daily Loads. N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Pollution monitoring; Environmental assessment; Anthropogenic factors; Sampling; Watersheds; Water quality; Environmental protection; EPA; water quality; Landscape; Remote sensing; Geographic information systems; Streams; Variability; Assessments; Networks; Water Quality; Environmental Protection; Monitoring; Geographical Information Systems; USA, New Hampshire DO - http://dx.doi.org/10.1061/(ASCE)0733-9372(2004)130:6(622) ER - TY - JOUR T1 - Preparation, properties, and mathematical modeling of microparticle drug delivery systems based on biodegradable amphiphilic triblock copolymers AN - 19477928; 8216829 AB - A series of biodegradable amphiphilic A-B-A type triblock copolymers P(BLA-PEG-BLA), composed of hydrophilic poly(ethylene glycol) (PEG) as a middle block component (B) and hydrophobic poly(-benzyl-L-aspartate) as outer polypeptide block components (A), were synthesized by copolymerization of -benzyl-L-aspartate N-carboxy anhydride (BLA-NCA) and the diaminated PEG with the primary amino groups capped at both ends. These P(BLA-PEG-BLA) copolymers were characterized by 1H-NMR, DSC, and GPC. The triblock copolymers were used to prepare three kinds of drug delivery systems including Norfloxacin (INN)-incorporated P(BLA-PEG-BLA) microparticles and tablets. The morphologies of the microparticles were characterized by SEM. The in vitro release properties of the microparticles and tablets in PBS were also evaluated. A mathematical model, which incorporates a linear first-order dissolution term and the transient Fickian diffusion equation, was developed to account for the kinetics of drug release from the INN-incorporated P(BLA-PEG-BLA) microparticles. The results indicated that the overall release process was well controlled by both drug dissolution and diffusion. JF - Journal of Applied Polymer Science AU - Yan, Guo-Ping AU - Li, Hua AU - Cheng, Si-Xue AU - Bottle, Steven E AU - Wang, Xiao-Gui AU - Yew, Yong Kin AU - Zhuo, Ren-Xi AD - School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Q4001, Australia, guopyan@hotmail.com Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 3869 EP - 3873 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk], [URL:http://www.wiley.com/] VL - 92 IS - 6 SN - 0021-8995, 0021-8995 KW - Biotechnology and Bioengineering Abstracts KW - Drug delivery KW - Norfloxacin KW - Amino groups KW - Mathematical models KW - microparticles KW - Tablets KW - Hydrophobicity KW - Kinetics KW - Copolymers KW - Dissolution KW - Diffusion KW - Polyethylene glycol KW - W 30915:Pharmaceuticals & Vaccines UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19477928?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Polymer+Science&rft.atitle=Preparation%2C+properties%2C+and+mathematical+modeling+of+microparticle+drug+delivery+systems+based+on+biodegradable+amphiphilic+triblock+copolymers&rft.au=Yan%2C+Guo-Ping%3BLi%2C+Hua%3BCheng%2C+Si-Xue%3BBottle%2C+Steven+E%3BWang%2C+Xiao-Gui%3BYew%2C+Yong+Kin%3BZhuo%2C+Ren-Xi&rft.aulast=Yan&rft.aufirst=Guo-Ping&rft.date=2004-06-01&rft.volume=92&rft.issue=6&rft.spage=3869&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Polymer+Science&rft.issn=00218995&rft_id=info:doi/10.1002%2Fapp.20410 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-01-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Drug delivery; Amino groups; Norfloxacin; Mathematical models; microparticles; Kinetics; Tablets; Copolymers; Dissolution; Hydrophobicity; Diffusion; Polyethylene glycol DO - http://dx.doi.org/10.1002/app.20410 ER - TY - JOUR T1 - Monoterpenes and Epicuticular Waxes Help Female Autumn Gum Moth Differentiate Between Waxy and Glossy Eucalyptus and Leaves of Different Ages AN - 18065231; 6023312 AB - The autumn gum moth, Mnesampela privata, is a native Australian species whose preferred host, Eucalyptus globulus (Myrtaceae), is an aromatic evergreen tree that has long-lived waxy leaves during the juvenile phase of growth. We compared the behavioral and antennal responses of female moths to whole leaves (new and old) and samples of foliar chemicals (from new and old leaves) from a typical E. globulus subsp. pseudoglobulus with responses to a glossy, half-sibling E. g. subsp. pseudoglobulus putative hybrid (the result of natural cross-pollination). We also studied larval survival and development on leaves from the same trees. In laboratory binary-choice assays, female M. privata laid more eggs on waxy leaves than on glossy leaves thereby confirming the nonpreference for the glossy tree that was observed in the field. Analyses of the monoterpenes and waxes of both trees revealed that they had comparable suites of monoterpenes and total oil contents but different suites of epicuticular waxes. Headspace extracts differed in the intensity of component monoterpenes. Gas chromatographic analyses with electroantennographic detection showed different patterns of monoterpene detection. Leaves of the glossy tree had a less diverse array of epicuticular waxes than those of the waxy tree. Electroantennographic screening of responses to wax extracts from leaves (new and old) from either tree revealed positive dose-dependent responses of female antennae to waxes from new leaves only. Binary-choice assays also revealed a strong preference by ovipositing females for new, compared to old, leaves whether they were from the waxy or the glossy tree. However, new leaves from either tree could be manipulated (by physical abrasion of epicuticular waxes) so that females would lay almost no eggs on them. Larval survival did not differ between groups reared on leaves from both trees (new and old). Over 70% of all larvae survived to pupation. However, larvae reared on leaves from the glossy tree took longer to pupate than those reared on leaves from the waxy tree. Also, larvae reared on new leaves from either tree did not perform as well as those reared on old leaves. Monoterpene and wax cues are suggested as helping female M. privata locate preferred hosts in native forests. JF - Journal of Chemical Ecology AU - Steinbauer, MJ AU - Schiestl, F P AU - Davies, N W AD - CRC for Sustainable Production Forestry and CSIRO Entomology, G.P.O. Box 1700, Canberra, A.C.T. 2601, Australia, martin.steinbauer@csiro.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1117 EP - 1142 PB - Kluwer Academic Publishers VL - 30 IS - 6 SN - 0098-0331, 0098-0331 KW - Bluegum eucalyptus KW - Autumn gum moth KW - Myrtles KW - Chemoreception Abstracts; Animal Behavior Abstracts; Entomology Abstracts; Ecology Abstracts KW - Fitness KW - Leaf characters KW - Myrtaceae KW - Monoterpenes KW - Waxes KW - Eucalyptus globulus KW - Mnesampela privata KW - Host preferences KW - Defense mechanisms KW - Oviposition KW - Z 05203:Relations to plants KW - D 04659:Insects KW - Y 25503:Insects KW - R 18051:Reproductive behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18065231?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Chemical+Ecology&rft.atitle=Monoterpenes+and+Epicuticular+Waxes+Help+Female+Autumn+Gum+Moth+Differentiate+Between+Waxy+and+Glossy+Eucalyptus+and+Leaves+of+Different+Ages&rft.au=Steinbauer%2C+MJ%3BSchiestl%2C+F+P%3BDavies%2C+N+W&rft.aulast=Steinbauer&rft.aufirst=MJ&rft.date=2004-06-01&rft.volume=30&rft.issue=6&rft.spage=1117&rft.isbn=&rft.btitle=&rft.title=Journal+of+Chemical+Ecology&rft.issn=00980331&rft_id=info:doi/10.1023%2FB%3AJOEC.0000030267.75347.c1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eucalyptus globulus; Mnesampela privata; Myrtaceae; Host preferences; Fitness; Oviposition; Defense mechanisms; Leaf characters; Waxes; Monoterpenes DO - http://dx.doi.org/10.1023/B:JOEC.0000030267.75347.c1 ER - TY - JOUR T1 - Reliability of EMG measurements for trunk muscles during maximal and sub-maximal voluntary isometric contractions in healthy controls and CLBP patients AN - 17932360; 5886208 AB - The purpose of this study was to compare the reliability of trunk muscle activity measured by means of surface electromyography (EMG) during maximal and sub-maximal voluntary isometric contractions (MVC/sub-MVC) over repeated trials within-day and between-days in healthy controls and patients with chronic low back pain (CLBP). Eleven volunteers (six controls and five CLBP patients) were assessed twice with a 1-week interval. Surface EMG signals were recorded bilaterally from six trunk muscles. Intra-class correlation coefficients (ICC) and standard error of measurement as a percentage of the grand mean (%SEM) were calculated. MVC and sub-MVC showed excellent within-day reliability in both healthy controls and CLBP patients (ICC mean 0.91; range 0.75-0.98; %SEM mean 4%; range 1-12%). Sub-MVC for both groups between-days showed excellent reliability (ICC mean 0.88; range 0.78-0.97; %SEM mean 7%; range 3-11%). The between-days MVC for both groups showed trends towards lower levels of reliability (ICC mean 0.70; range 0.19-0.99; %SEM mean 17%; range 4-36%) when compared to sub-MVC. Findings of the study provide evidence that sub-MVC are preferable for amplitude normalisation when assessing EMG signals of trunk muscles between-days. JF - Journal of Electromyography and Kinesiology AU - Dankaerts, W AU - O'Sullivan, P B AU - Burnett, A F AU - Straker, L M AU - Danneels, LA AD - School of Physiotherapy, Bld 408, Curtin University of Technology, GPO Box U1987, Perth, 6845, WA, Australia, dankaerw@ses.curtin.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 333 EP - 342 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 14 IS - 3 SN - 1050-6411, 1050-6411 KW - Physical Education Index KW - Trunk KW - Electromyography KW - Isometrics KW - Muscles (contractions) KW - PE 100:Kinesiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17932360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Electromyography+and+Kinesiology&rft.atitle=Reliability+of+EMG+measurements+for+trunk+muscles+during+maximal+and+sub-maximal+voluntary+isometric+contractions+in+healthy+controls+and+CLBP+patients&rft.au=Dankaerts%2C+W%3BO%27Sullivan%2C+P+B%3BBurnett%2C+A+F%3BStraker%2C+L+M%3BDanneels%2C+LA&rft.aulast=Dankaerts&rft.aufirst=W&rft.date=2004-06-01&rft.volume=14&rft.issue=3&rft.spage=333&rft.isbn=&rft.btitle=&rft.title=Journal+of+Electromyography+and+Kinesiology&rft.issn=10506411&rft_id=info:doi/10.1016%2Fj.jelekin.2003.07.001 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Electromyography; Isometrics; Muscles (contractions); Trunk DO - http://dx.doi.org/10.1016/j.jelekin.2003.07.001 ER - TY - JOUR T1 - Identifying hazards in complex ecological systems. Part 3: Hierarchical Holographic Model for herbicide tolerant oilseed rape AN - 17880595; 6101303 AB - This paper is the third in a series designed to demonstrate the application of rigorous, systematic hazard identification techniques to ecological systems. Here we use Hierarchical Holographic Modelling to identify the potential ecological hazards associated with the commercial release of herbicide tolerant oilseed rape. Hierarchical Holographic Models decompose complex systems into a series of sub-systems and consider interactions between the components and processes of these sub-systems in order to identify hazards. In this example we considered 1356 potential interactions between the biological, chemical and physical components and processes of the herbicide tolerant oilseed rape environment, and identified 152 potential hazards, grouped into 14 categories. The hazards were subsequently scored for degree of concern and plausibility, and then compared with an equivalent list of hazards generated independently by a checklist approach. The incidence of herbicide tolerant volunteers (and weeds) both on and off the farm had the highest average score of all the ecological hazard categories. The checklist based approach identified or implied 44% of the hazards identified in the Hierarchical Holographic Model, including nine of the ten hazards ranked most important. The checklist approach focussed almost exclusively on the phenotypic and genotypic hazards associated with herbicide tolerant oilseed rape and largely ignored the hazards associated with the circumstances surrounding its use. As a result the checklist identified only 6 out of the 79 potential hazards associated with changes to farming practice. The commercial release of herbicide tolerant oilseed rape will be associated with changes in tillage and the application of post-emergent herbicides. It may also lead to changes in spray schedules of insecticide and fungicide. Many of the environmental hazards identified with these changes are plausible and may warrant further investigation or targeted monitoring. JF - Environmental Biosafety Research AU - Hayes, K R AU - Gregg, P C AU - Gupta, VVSR AU - Jessop, R AU - Lonsdale, WM AU - Sindel, B AU - Stanley, J AU - Williams, C K AD - CSIRO Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, keith.hayes@csiro.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 109 EP - 128 VL - 3 IS - 2 SN - 1635-7922, 1635-7922 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Weeds KW - Insecticides KW - Farms KW - Mathematical models KW - Tillage KW - Fungicides KW - Check lists KW - Herbicides KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880595?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Biosafety+Research&rft.atitle=Identifying+hazards+in+complex+ecological+systems.+Part+3%3A+Hierarchical+Holographic+Model+for+herbicide+tolerant+oilseed+rape&rft.au=Hayes%2C+K+R%3BGregg%2C+P+C%3BGupta%2C+VVSR%3BJessop%2C+R%3BLonsdale%2C+WM%3BSindel%2C+B%3BStanley%2C+J%3BWilliams%2C+C+K&rft.aulast=Hayes&rft.aufirst=K&rft.date=2004-06-01&rft.volume=3&rft.issue=2&rft.spage=109&rft.isbn=&rft.btitle=&rft.title=Environmental+Biosafety+Research&rft.issn=16357922&rft_id=info:doi/10.1051%2Febr%3A2004012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Herbicides; Check lists; Mathematical models; Fungicides; Farms; Insecticides; Weeds; Tillage DO - http://dx.doi.org/10.1051/ebr:2004012 ER - TY - JOUR T1 - Comparison between closed-loop portal and peripheral venous insulin delivery systems for an artificial endocrine pancreas AN - 17585830; 6001372 AB - To establish the ideal insulin delivery route for an artificial endocrine pancreas, we examined the effectiveness of closed-loop portal insulin delivery. We investigated the effects of the route of insulin delivery on net hepatic glucose balance (NHGB) in dogs under pancreatic clamp conditions with somatostatin plus basal glucagon and insulin infusions. A constant rate of suprabasal insulin was infused via the portal vein or a peripheral vein, and glucose was infused into the portal vein for 180 min. The mean net hepatic glucose uptake (NHGU) values in the portal insulin infusion group (PI group) were significantly greater than those in the peripheral venous insulin infusion group (VI group); the changes from the baseline values at 180 min were 3.54 plus or minus 0.66 and 2.45 plus or minus 0.82 mg kg super(-1) min super(-1) in the PI and VI groups, respectively, P < 0.05. Furthermore, dogs under pancreatic clamp conditions were controlled after a 2-g/kg oral glucose load by applying the closed-loop intraportal (PO) or intravenous (IV) insulin infusion algorithm. There were no significant differences in glycemic control and insulin requirements between these algorithms. However, the maximum peripheral venous and arterial plasma insulin concentrations with the PO algorithm were significantly lower than those with the IV algorithm [305.1 plus or minus 68.9 and 468.1 plus or minus 66.9 pmol/l (peripheral vein) and 305.3 plus or minus 62.9 and 469.6 plus or minus 85.1 pmol/l (artery) with the PO and IV algorithms, respectively, P < 0.05]. On the other hand, the maximum portal plasma insulin concentration with the PO algorithm was significantly higher than that with the IV algorithm (619.9 plus or minus 101.7 and 414.3 plus or minus 79.9 pmol/l with the PO and IV algorithms, respectively, P < 0.05). The mean NHGU values with the PO algorithm were significantly greater than those with the IV algorithm. Our results confirmed that closed-loop portal insulin delivery is feasible with regard to both insulin profiles and hepatic glucose handling in vivo, and indicated that the portal vein is the most suitable insulin delivery route for the artificial endocrine pancreas. JF - Journal of Artificial Organs AU - Sekigami, Taiji AU - Shimoda, Seiya AU - Nishida, Kenro AU - Matsuo, Yasuto AU - Ichimori, Shinji AU - Ichinose, Kenshi AU - Shichiri, Motoaki AU - Sakakida, Michiharu AU - Araki, Eiichi AD - Department of Metabolic Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan, sshimoda@gpo.kumamoto-u.ac.jp Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 91 EP - 100 VL - 7 IS - 2 SN - 1434-7229, 1434-7229 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Drug delivery KW - Arteries KW - Glucagon KW - Pancreas KW - Glucose KW - Algorithms KW - Portal vein KW - Somatostatin KW - Insulin KW - Veins KW - Liver KW - artificial organs KW - W 30965:Miscellaneous, Reviews KW - W4 110:Biomedical Materials & Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17585830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Artificial+Organs&rft.atitle=Comparison+between+closed-loop+portal+and+peripheral+venous+insulin+delivery+systems+for+an+artificial+endocrine+pancreas&rft.au=Sekigami%2C+Taiji%3BShimoda%2C+Seiya%3BNishida%2C+Kenro%3BMatsuo%2C+Yasuto%3BIchimori%2C+Shinji%3BIchinose%2C+Kenshi%3BShichiri%2C+Motoaki%3BSakakida%2C+Michiharu%3BAraki%2C+Eiichi&rft.aulast=Sekigami&rft.aufirst=Taiji&rft.date=2004-06-01&rft.volume=7&rft.issue=2&rft.spage=91&rft.isbn=&rft.btitle=&rft.title=Journal+of+Artificial+Organs&rft.issn=14347229&rft_id=info:doi/10.1007%2Fs10047-004-0251-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Insulin; Algorithms; Glucose; Pancreas; Liver; Portal vein; Veins; artificial organs; Drug delivery; Somatostatin; Glucagon; Arteries DO - http://dx.doi.org/10.1007/s10047-004-0251-2 ER - TY - JOUR T1 - A randomized trial of interactive group sessions achieved greater improvements in nutrition and physical activity at a tiny increase in cost AN - 17582896; 6001345 AB - Weight gain may follow altered eating habits and decreased physical activity in couples beginning to live together. Mutual support and willingness to accept changes in lifestyle at this stage may facilitate positive responses to health promotion. We aimed to compare the effects of a diet and physical activity program in couples using a randomized controlled trial. Couples were randomized to a control group or to one of two intervention groups in whom the program was either delivered mainly by mail or with a combination of mail-outs and interactive group sessions. Diets, physical fitness, and blood cholesterol improved up to 12 months after beginning the 4-month program, mainly in the interactive group. In that group, at the end of the program, the estimated cost was $445.30 ($111.33/month) per participant per unit change in outcome variables, only $0.03 per participant per month more than the group receiving the program mainly by mail. One year after beginning the program, costs per participant per month were $38.37 in the interactive group and $38.22 in the group receiving the program mainly by mail-out. The changes observed in cardiovascular risk factors could translate to a substantial cost-savings relating to health. JF - Journal of Clinical Epidemiology AU - Dzator, JA AU - Hendrie, D AU - Burke, V AU - Gianguilio, N AU - Gillam, H F AU - Beilin, L J AU - Houghton, S AD - School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit and West Australian Institute for Medical Research, Box X2213 GPO, Perth 6847, Western Australia, vburke@cyllene.uwa.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 610 EP - 619 VL - 57 IS - 6 SN - 0895-4356, 0895-4356 KW - Physical Education Index KW - Diet (effects) KW - Programs KW - Promotion KW - Lipids KW - Diet (weight control) KW - Intervention KW - Health KW - Exercise KW - Nutrition KW - Exercise (programs) KW - Lifestyle KW - Blood KW - Social support KW - Risk factors KW - Physical fitness KW - Economics KW - Cardiorespiratory KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17582896?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Epidemiology&rft.atitle=A+randomized+trial+of+interactive+group+sessions+achieved+greater+improvements+in+nutrition+and+physical+activity+at+a+tiny+increase+in+cost&rft.au=Dzator%2C+JA%3BHendrie%2C+D%3BBurke%2C+V%3BGianguilio%2C+N%3BGillam%2C+H+F%3BBeilin%2C+L+J%3BHoughton%2C+S&rft.aulast=Dzator&rft.aufirst=JA&rft.date=2004-06-01&rft.volume=57&rft.issue=6&rft.spage=610&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Epidemiology&rft.issn=08954356&rft_id=info:doi/10.1016%2Fj.jclinepi.2003.10.009 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Programs; Exercise; Economics; Social support; Diet (effects); Health; Cardiorespiratory; Lipids; Blood; Promotion; Intervention; Lifestyle; Risk factors; Physical fitness; Exercise (programs); Nutrition; Diet (weight control) DO - http://dx.doi.org/10.1016/j.jclinepi.2003.10.009 ER - TY - JOUR T1 - Identification and Characterization of the Novel LysM Domain-Containing Surface Protein Sep from Lactobacillus fermentum BR11 and Its Use as a Peptide Fusion Partner in Lactobacillus and Lactococcus AN - 17352780; 6406775 AB - Examination of supernatant fractions from broth cultures of Lactobacillus fermentum BR11 revealed the presence of a number of proteins, including a 27-kDa protein termed Sep. The amino-terminal sequence of Sep was determined, and the gene encoding it was cloned and sequenced. Sep is a 205-amino-acid protein and contains a 30-amino-acid secretion signal and has overall homology (between 39 and 92% identity) with similarly sized proteins of Lactobacillus reuteri, Enterococcus faecium, Streptococcus pneumoniae, Streptococcus agalactiae, and Lactobacillus plantarum. The carboxy-terminal 81 amino acids of Sep also have strong homology (86% identity) to the carboxy termini of the aggregation-promoting factor (APF) surface proteins of Lactobacillus gasseri and Lactobacillus johnsonii. The mature amino terminus of Sep contains a putative peptidoglycan-binding LysM domain, thereby making it distinct from APF proteins. We have identified a common motif within LysM domains that is shared with carbohydrate binding YG motifs which are found in streptococcal glucan-binding proteins and glucosyltransferases. Sep was investigated as a heterologous peptide expression vector in L. fermentum, Lactobacillus rhamnosus GG and Lactococcus lactis MG1363. Modified Sep containing an amino-terminal six-histidine epitope was found associated with the cells but was largely present in the supernatant in the L. fermentum, L. rhamnosus, and L. lactis hosts. Sep as well as the previously described surface protein BspA were used to express and secrete in L. fermentum or L. rhamnosus a fragment of human E-cadherin, which contains the receptor region for Listeria monocytogenes. This study demonstrates that Sep has potential for heterologous protein expression and export in lactic acid bacteria. JF - Applied and Environmental Microbiology AU - Turner AU - Hafner, L M AU - Walsh, T AU - Giffard, P M AD - Infectious Diseases Program, School of Life Sciences, Faculty of Science, Queensland University of Technology, G.P.O. Box 2434, Brisbane, Queensland 4001, Australia, ms.turner@qut.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 3673 EP - 3680 VL - 70 IS - 6 SN - 0099-2240, 0099-2240 KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Microbiology Abstracts B: Bacteriology KW - W2 32340:Other peptides, proteins, amino acids KW - W 30965:Miscellaneous, Reviews KW - J 02727:Amino acids, peptides and proteins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17352780?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Identification+and+Characterization+of+the+Novel+LysM+Domain-Containing+Surface+Protein+Sep+from+Lactobacillus+fermentum+BR11+and+Its+Use+as+a+Peptide+Fusion+Partner+in+Lactobacillus+and+Lactococcus&rft.au=Turner%3BHafner%2C+L+M%3BWalsh%2C+T%3BGiffard%2C+P+M&rft.aulast=Turner&rft.aufirst=&rft.date=2004-06-01&rft.volume=70&rft.issue=6&rft.spage=3673&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.70.6.3673-3680.2004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1128/AEM.70.6.3673-3680.2004 ER - TY - JOUR T1 - Measurement and prediction of energy expenditure in males during household and garden tasks AN - 17255248; 6988947 JF - European Journal of Applied Physiology AU - Gunn, S M AU - van der Ploeg, GE AU - Withers, R T AU - Gore, C J AU - Owen, N AU - Bauman, A E AU - Cormack, J AD - Exercise Physiology Laboratory, School of Education, Flinders University, GPO Box 2100, Adelaide, South Australia, Australia 5001, bob.withers@flinders.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 231 VL - 92 IS - 1-2 SN - 1439-6319, 1439-6319 KW - Physical Education Index KW - Energy cost KW - Measurement KW - Men KW - Activities KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17255248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Applied+Physiology&rft.atitle=Measurement+and+prediction+of+energy+expenditure+in+males+during+household+and+garden+tasks&rft.au=Gunn%2C+S+M%3Bvan+der+Ploeg%2C+GE%3BWithers%2C+R+T%3BGore%2C+C+J%3BOwen%2C+N%3BBauman%2C+A+E%3BCormack%2C+J&rft.aulast=Gunn&rft.aufirst=S&rft.date=2004-06-01&rft.volume=92&rft.issue=1-2&rft.spage=231&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Applied+Physiology&rft.issn=14396319&rft_id=info:doi/10.1007%2Fs00421-004-1100-y LA - English DB - Physical Education Index N1 - Date revised - 2006-08-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Measurement; Activities; Men; Energy cost DO - http://dx.doi.org/10.1007/s00421-004-1100-y ER - TY - JOUR T1 - Vacuum ultraviolet irradiation for natural organic matter removal AN - 16174011; 5997434 AB - Low pressure mercury vapour lamps were used alone and in combination with hydrogen peroxide (H sub(2)O sub(2)) to investigate the removal of natural organic matter (NOM) from highly coloured surface water, high in total organic carbon (TOC). A potential benefit of vacuum ultraviolet (VUV) irradiation is additive-free degradation of NOM by hydroxyl radicals rather than concentration and subsequent disposal problems associated with many conventional techniques. For mineralization and chromophore removal the UV/VUV/H sub(2)O sub(2) combination was most effective, followed by UV/VUV. Photooxidation alone was inappropriate because small (but much greater than normal UV disinfection doses) and intermediate doses increased chlorine demand, trihalomethane formation potential, nitrite, hydrogen peroxide and low molecular weight carbonyl compound concentrations. Subsequent biological treatment reduced the chlorine reactivity significantly, by removal of oxidized NOM intermediates. Low molecular weight carbonyl compound concentrations in the water increased significantly on irradiation, and differences in their speciation indicated that different reaction mechanisms were dominant in different treatments. Trihalomethane (THM) distribution shifted to more highly brominated compounds as the NOM concentration decreased with treatment. Results from this preliminary study indicate that NOM can be removed from water by VUV irradiation combined with biological treatment leading to improved drinking water quality. JF - Aqua - Journal of Water Supply: Research and Technology AU - Thomson, J AU - Roddick, F A AU - Drikas, M AD - School of Civil and Chemical Engineering, RMIT University, GPO Box 2476V, Melbourne, Victoria 3001, Australia, felicity.roddick@rmit.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 193 EP - 206 VL - 53 IS - 4 SN - 0003-7214, 0003-7214 KW - Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Disinfection KW - Speciation KW - Degradation KW - Hydrogen Peroxide KW - Surface water KW - Water Supply KW - Surface Water KW - Drinking Water KW - Organic Matter KW - Water treatment KW - Distribution KW - Ultraviolet radiation KW - Water Treatment KW - Hydroxyl Radical KW - Organic Carbon KW - Organic matter KW - Hydroxyl radicals KW - Nitrites KW - Trihalomethanes KW - Irradiation KW - Mercury KW - Chlorination KW - Drinking water KW - Biological Treatment KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - AQ 00004:Water Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16174011?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aqua+-+Journal+of+Water+Supply%3A+Research+and+Technology&rft.atitle=Vacuum+ultraviolet+irradiation+for+natural+organic+matter+removal&rft.au=Thomson%2C+J%3BRoddick%2C+F+A%3BDrikas%2C+M&rft.aulast=Thomson&rft.aufirst=J&rft.date=2004-06-01&rft.volume=53&rft.issue=4&rft.spage=193&rft.isbn=&rft.btitle=&rft.title=Aqua+-+Journal+of+Water+Supply%3A+Research+and+Technology&rft.issn=00037214&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-01-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Water treatment; Nitrites; Surface water; Irradiation; Trihalomethanes; Organic matter; Ultraviolet radiation; Chlorination; Drinking water; Hydroxyl radicals; Hydroxyl Radical; Speciation; Disinfection; Degradation; Hydrogen Peroxide; Organic Carbon; Water Supply; Surface Water; Drinking Water; Organic Matter; Distribution; Water Treatment; Mercury; Biological Treatment ER - TY - JOUR T1 - Endangered Species: Difficult Choices AN - 14718682; 10673303 AB - Different proposals to amend the 1973 Endangered Species Act (ESA) are being considered by the 108th Congress. Major issues of debate concern specific regional resource conflicts, use of sound science, critical habitat designation, private property and takings, and rendering the ESA more user-friendly. Legislation was submitted to provide FY2004 USDI appropriations of $265 million for programs related to endangered species, and to direct that critical habitat not be designated on military lands under certain conditions when Integrated Natural Resources Management Plans are in effect. Additional statutes directed that a healthy forests reserve program be established to promote recovery of threatened and endangered species. JF - US Congressional Research Service Report IB10072 AU - Corn, MLynne AU - Buck, Eugene H AU - Baldwin, Pamela Y1 - 2004/06// PY - 2004 DA - Jun 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - ENDANGERED SPECIES ACT 73 KW - LEGISLATION, FEDERAL KW - FOREST MANAGEMENT KW - LAND MANAGEMENT KW - ENV RESTORATION KW - WILDLIFE MANAGEMENT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718682?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10072&rft.atitle=Endangered+Species%3A+Difficult+Choices&rft.au=Corn%2C+MLynne%3BBuck%2C+Eugene+H%3BBaldwin%2C+Pamela&rft.aulast=Corn&rft.aufirst=MLynne&rft.date=2004-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10072&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV RESTORATION; LEGISLATION, FEDERAL; ENDANGERED SPECIES ACT 73; FOREST MANAGEMENT; WILDLIFE MANAGEMENT; LAND MANAGEMENT ER - TY - JOUR T1 - Spatial Analysis of the Relationship Between Mortality from Cardiovascular and Cerebrovascular Disease and Drinking Water Hardness AN - 14701157; 10663802 AB - The Spanish Rapid Inquiry Facility (RIF), which is an analytical tool for quick assessment that is applied to data gathered in the information system developed within the European Health and Environment Information System, was used to examine spatially the relationship between mortality from cardiovascular and cerebrovascular disease and drinking-water hardness in all municipalities of Comunidad Valenciana. Exposure analysis with RIF was performed by defining regions composed to geographical units sharing similar levels of the risk factor. A statistical analysis was performed using the estimation of the relative risk in each region by the corresponding standardized mortality ratio of observed to expected mortality counts. Results suggested a relationship between calcium and magnesium in water and the data on mortality from cerebrovascular and ischemic diseases. The relationship was stronger for cerebrovascular disease in women. JF - Environmental Health Perspectives AU - Ferrandiz, Juan AU - Abellan, Juan J AU - Gomez-Rubio, Virgilio AU - Lopez-Quilez, Antonio AU - Sanmartin, Pilar AU - Abellan, Carlos AU - Martinez-Beneito, Miguel A Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1037 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SPAIN KW - SPATIAL COMPARISONS KW - RISK ASSESSMENT KW - GEOGRAPHIC INFORMATION SYSTEMS KW - WATER HARDNESS KW - MORTALITY PATTERNS KW - CARDIOVASCULAR DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14701157?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Spatial+Analysis+of+the+Relationship+Between+Mortality+from+Cardiovascular+and+Cerebrovascular+Disease+and+Drinking+Water+Hardness&rft.au=Ferrandiz%2C+Juan%3BAbellan%2C+Juan+J%3BGomez-Rubio%2C+Virgilio%3BLopez-Quilez%2C+Antonio%3BSanmartin%2C+Pilar%3BAbellan%2C+Carlos%3BMartinez-Beneito%2C+Miguel+A&rft.aulast=Ferrandiz&rft.aufirst=Juan&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1037&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 19 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; SPAIN; GEOGRAPHIC INFORMATION SYSTEMS; WATER HARDNESS; MORTALITY PATTERNS; SPATIAL COMPARISONS; CARDIOVASCULAR DISORDERS ER - TY - JOUR T1 - Cancer Risk near a Polluted River in Finland AN - 14700183; 10663800 AB - Cancer risk was investigated in people living near the River Kymijoki, Finland, using the small-area statistics on health system designed for investigations of cancer risk near geographically defined exposure sources. Due to past contamination, the river sediments contain high levels of PCDDs and PCDFs. The study population was defined as all people living within 20 km from the river, and the study area was divided into nine sub-areas according to increasing distance to the river downstream from a factory producing the chlorophenol fungicide, Ky-5. Risk was assessed for total cancer and for 27 selected cancer types for all people, and separately for farmers, living near the river since the end of December 1980. Cancer incidence in all people, as well as in farmers, living close to the river was at the level expected based on national rates, For all people living less than 1 km from the river, however, the socioeconomic status-adjusted relative risks for total cancer were consistently greater than 1, and the relative risks for farmers were generally higher than the relative risks for all residents. JF - Environmental Health Perspectives AU - Verkasalo, Pia K AU - Kokki, Esa AU - Pukkala, Eero AU - Vartiainen, Terttu AU - Kiviranta, Hannu AU - Penttinen, Antti AU - Pekkanen, Juha Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1026 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - POLYCHLORINATED DIBENZODIOXINS KW - SPATIAL COMPARISONS KW - POLYCHLORINATED DIBENZOFURANS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - FINLAND KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700183?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cancer+Risk+near+a+Polluted+River+in+Finland&rft.au=Verkasalo%2C+Pia+K%3BKokki%2C+Esa%3BPukkala%2C+Eero%3BVartiainen%2C+Terttu%3BKiviranta%2C+Hannu%3BPenttinen%2C+Antti%3BPekkanen%2C+Juha&rft.aulast=Verkasalo&rft.aufirst=Pia&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1026&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t maps N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; GEOGRAPHIC INFORMATION SYSTEMS; POLYCHLORINATED DIBENZODIOXINS; SPATIAL COMPARISONS; FINLAND; POLYCHLORINATED DIBENZOFURANS ER - TY - JOUR T1 - Using Geographic Information Systems for Exposure Assessment in Environmental Epidemiology Studies AN - 14700154; 10663798 AB - The use of geographic information systems (GISs) in spatial statistics for linking exposure and health data in the context of epidemiologic analysis is a growing field of research. The fundamentals of the scientific disciplines required to use a GIS in such studies are discussed, focusing on four important areas: defining the study population, identifying source and potential routes of exposure, estimating environmental levels of target contaminants, and estimating personal exposures. Information obtained from the scientific literature suggest that a GIS can enhance epidemiologic research greatly in terms of the definition of source and routes of potential exposure and the estimation of environmental levels of target contaminants in the exposure assessment process. JF - Environmental Health Perspectives AU - Nuckols, John R AU - Ward, Mary H AU - Jarup, Lars Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1007 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GEOGRAPHIC INFORMATION SYSTEMS KW - PUBLIC HEALTH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+Geographic+Information+Systems+for+Exposure+Assessment+in+Environmental+Epidemiology+Studies&rft.au=Nuckols%2C+John+R%3BWard%2C+Mary+H%3BJarup%2C+Lars&rft.aulast=Nuckols&rft.aufirst=John&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1007&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GEOGRAPHIC INFORMATION SYSTEMS; PUBLIC HEALTH ER - TY - JOUR T1 - Rationale for a New Generation of Indicators for Coastal Waters AN - 14700072; 10663794 AB - Four critical areas are identified in which scientific advancements are needed before improvements can be made in indicator development of coastal regions. The areas, each of which is discussed, include: linking stress with response, multiple stressors of environmental condition, spatial and temporal explicitness, and reference conditions. Two brief examples are presented of new types of indicators, one that links productivity and hydrology and another than links community patterns. Analyses of photopigments can provide a means to explicitly link nutrient and hydrologic stressors with specific phytoplanton groups, while multitaxa types of approaches can provide a wide range of possibilities for improving the knowledge of stress-response relationships, the identification of multiple stressor effects, spatial and temporal explicitness, and the identification of suitable reference conditions. JF - Environmental Health Perspectives AU - Niemi, Gerald AU - Wardrop, Denice AU - Brooks, Robert AU - Anderson, Susan AU - Brady, Valerie AU - Paerl, Hans AU - Rakocinski, Chet Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 979 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - COASTAL WATERS KW - ESTUARIES KW - BIOLOGICAL INDICATORS, MARINE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Rationale+for+a+New+Generation+of+Indicators+for+Coastal+Waters&rft.au=Niemi%2C+Gerald%3BWardrop%2C+Denice%3BBrooks%2C+Robert%3BAnderson%2C+Susan%3BBrady%2C+Valerie%3BPaerl%2C+Hans%3BRakocinski%2C+Chet&rft.aulast=Niemi&rft.aufirst=Gerald&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=979&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; COASTAL WATERS; ESTUARIES; BIOLOGICAL INDICATORS, MARINE ER - TY - JOUR T1 - Use of GIS and Exposure Modeling as Tools in a Study of Cancer Incidence in a Population Exposed to Airborne Dioxin AN - 14699661; 10663801 JF - Environmental Health Perspectives AU - Poulstrup, A AU - Hansen, H L Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1032 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DENMARK KW - MATHEMATIC MODELS, AIR KW - CANCER RISK KW - AIR POLLUTION EFFECTS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - DIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699661?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Use+of+GIS+and+Exposure+Modeling+as+Tools+in+a+Study+of+Cancer+Incidence+in+a+Population+Exposed+to+Airborne+Dioxin&rft.au=Poulstrup%2C+A%3BHansen%2C+H+L&rft.aulast=Poulstrup&rft.aufirst=A&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1032&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MATHEMATIC MODELS, AIR; DENMARK; CANCER RISK; AIR POLLUTION EFFECTS; GEOGRAPHIC INFORMATION SYSTEMS; DIOXINS ER - TY - JOUR T1 - Pesticide Testing in Humans: Ethics and Public Policy AN - 14699511; 10663565 AB - An expert workshop was convened in February 2002 by the Center for Children's Health and the Environment of the Mount Sinai School of Medicine to discuss the ethics of pesticide testing in humans. The history of such testing in the US is reviewed, and the ethical issues are highlighted. Several recommendations agreed upon by the participants are proposed that address the need to establish ethical guidelines for US EPA studies and ethical constraints on research. JF - Environmental Health Perspectives AU - Oleskey, Christopher AU - Fleischman, Alan AU - Goldman, Lynn AU - Hirschhorn, Kurt AU - Landrigan, Philip J AU - Lappe, Marc AU - Marshall, Mary Faith Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 914 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ENV ETHICS KW - MEASUREMENTS AND SENSING KW - DOSE RESPONSE PROFILES KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pesticide+Testing+in+Humans%3A+Ethics+and+Public+Policy&rft.au=Oleskey%2C+Christopher%3BFleischman%2C+Alan%3BGoldman%2C+Lynn%3BHirschhorn%2C+Kurt%3BLandrigan%2C+Philip+J%3BLappe%2C+Marc%3BMarshall%2C+Mary+Faith&rft.aulast=Oleskey&rft.aufirst=Christopher&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=914&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 40 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; ENV ETHICS; DOSE RESPONSE PROFILES; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Sample Characterization of Automobile and Forklift Diesel Exhaust Particles and Comparative Pulmonary Toxicity in Mice AN - 14699490; 10663550 AB - Mice were exposed by involuntary aspiration to 0, 25, or 100 mu g of automobile diesel exhaust particles (DEPs) or forklift DEPs, the latter being the National Institute of Standards Technology standard reference material, and pulmonary inflammation and lung injury were evaluated in bronchoalveolar lavage fluid at 4 and 18 h after exposure. Animals were also exposed to a dose of an organic extract of the DEPs equivalent to the proportional mass of the fraction present in a 100- mu g dose of the particle sample. Results showed that the two DEP samples differed in size, texture, and color. The two DEPs produced similar levels of acute pulmonary injury and interleukin-6, but induced distinctly different cellular inflammatory responses. The forklift DEPs caused an increase in polymorphonuclear cells, while the automobile DEPs caused an increase in macrophages, which suggested divergent mechanisms of cellular recruitment and activation. For both DEP samples, the increases in bronchoalveolar lavage fluid polymorphonuclear cells or macrophages were dose-dependent. JF - Environmental Health Perspectives AU - Singh, Pramila AU - DeMarini, David M AU - Dick, Colin AJ AU - Tabor, Dennis G AU - Ryan, Jeff V AU - Linak, William P AU - Kobayashi, Takahiro Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 820 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSE RESPONSE PROFILES KW - DIESEL ENGINES, TRANSPORT KW - AUTOMOBILE EMISSIONS KW - PULMONARY EFFECTS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699490?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Sample+Characterization+of+Automobile+and+Forklift+Diesel+Exhaust+Particles+and+Comparative+Pulmonary+Toxicity+in+Mice&rft.au=Singh%2C+Pramila%3BDeMarini%2C+David+M%3BDick%2C+Colin+AJ%3BTabor%2C+Dennis+G%3BRyan%2C+Jeff+V%3BLinak%2C+William+P%3BKobayashi%2C+Takahiro&rft.aulast=Singh&rft.aufirst=Pramila&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=820&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; DIESEL ENGINES, TRANSPORT; AUTOMOBILE EMISSIONS; PULMONARY EFFECTS; PARTICULATES ER - TY - JOUR T1 - Estradiol Uptake, Toxicity, Metabolism, and Adverse Effects on Cadmium-Treated Amphibian Embryos AN - 14699419; 10663556 AB - The toxicity of 17 beta -estradiol, its uptake and metabolism, and the effect of 17 beta -estradiol on cadmium toxicity were examined in embryos of the South American toad Bufo arenarum. The LC sub(50) values for 17 beta -estradiol at 48 and 96 h of exposure decreased from 33.69 to 15.13 mu mol/l. Uptake of 17 beta -estradiol at 0.5, 1.0, 2.0, 4.0, and 8.0 h was 13.52, 17.15, 19.17, 19.38, and 20.10 ng/mg, respectively. At low 17 beta -estradiol exposure concentrations, Cd toxicity was enhanced within the first 24 h of exposure, and the tendency was maintained until the third day of exposure. By day seven, however, no differences were observed between the embryos treated with Cd plus 17 beta -estradiol and those treated with Cd alone. JF - Environmental Health Perspectives AU - Fridman, Osvaldo AU - Corro, Lucrecia AU - Herkovits, Jorge Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 862 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOACCUMULATION, ANIMAL KW - CADMIUM KW - HORMONES KW - TOADS KW - DOSE RESPONSE PROFILES KW - METABOLIC ACTIVATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Estradiol+Uptake%2C+Toxicity%2C+Metabolism%2C+and+Adverse+Effects+on+Cadmium-Treated+Amphibian+Embryos&rft.au=Fridman%2C+Osvaldo%3BCorro%2C+Lucrecia%3BHerkovits%2C+Jorge&rft.aulast=Fridman&rft.aufirst=Osvaldo&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=862&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOACCUMULATION, ANIMAL; DOSE RESPONSE PROFILES; TOADS; METABOLIC ACTIVATION; CADMIUM; HORMONES ER - TY - JOUR T1 - Adipose Tissue Levels of Organochlorine Pesticides and Polychlorinated Biphenyls and Risk of Non-Hodgkin's Lymphoma AN - 14699384; 10663555 AB - Data from an EPA study of organochlorine pesticide and PCB exposure in the general population, which involved examination of adipose tissue from postmortem and surgical specimens, were used to examine the association between the risk of non-Hodgkin's lymphoma (NHL) and adipose organochlorine pesticide and PCB levels using a case-control study design. The cases were those in the data set who had a diagnosis of NHL, and controls were selected from subjects with a diagnosis of accidental injury or death and no cancer diagnosis, and from subjects with a diagnosis of myocardial infarction and no cancer diagnosis. The controls were matched on age, sex, geographic region, and race. For all adipose residues, the mean was higher in cases than in controls, and levels were significantly higher for dieldrin, oxychlordane, heptachlor epoxide, and hexachlorobenzene. The DDT-related residue, p,p'-DDE, was significantly increased among cases in the highest quartile. The levels of beta -benzene hexachloride and dieldrin were associated significantly with NHL risk among cases in the highest exposure quartiles, but there were no significant associations of hexachlorobenzene or PCBs with NHL risk. Higher levels of oxychlordane and heptachlor epoxide were associated significantly with the odds of NHL. JF - Environmental Health Perspectives AU - Quintana, Penelope JE AU - Delfino, Ralph J AU - Korrick, Susan AU - Ziogas, Argyrios AU - Kutz, Frederick W AU - Jones, Ellen L AU - Laden, Francine Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 854 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - POLYCHLORINATED BIPHENYLS KW - ORGANOCHLORINE PESTICIDES KW - BIOACCUMULATION, HUMAN KW - DISEASES AND DISORDERS KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699384?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Adipose+Tissue+Levels+of+Organochlorine+Pesticides+and+Polychlorinated+Biphenyls+and+Risk+of+Non-Hodgkin%27s+Lymphoma&rft.au=Quintana%2C+Penelope+JE%3BDelfino%2C+Ralph+J%3BKorrick%2C+Susan%3BZiogas%2C+Argyrios%3BKutz%2C+Frederick+W%3BJones%2C+Ellen+L%3BLaden%2C+Francine&rft.aulast=Quintana&rft.aufirst=Penelope&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=854&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; POLYCHLORINATED BIPHENYLS; DISEASES AND DISORDERS; PESTICIDE EXPOSURE; BIOACCUMULATION, HUMAN; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Prediction of Residential Pet and Cockroach Allergen Levels Using Questionnaire Information AN - 14699365; 10663552 AB - Interviews were conducted in the homes of 932 newborns in Connecticut and Massachusetts to ascertain cat and dog ownership and the presence of cockroaches. Dust samples were collected during the home interviews and analyzed for the presence of major cat, dog, and German cockroach allergens using two-site monoclonal antibody-based enzyme-linked immunosorbent assays. The aim was to examine how accurately questionnaire-reported data predicted measured allergen levels. Results revealed that specificity was high for all three allergens, whereas sensitivity was low, particularly for current pet ownership and cat and dog allergens above the limit of detection and the lower cut point. Questionnaire-reported presence of cats was a relatively poor measure of cat allergen levels in house dust, whereas cockroach allergen in house dust was related strongly to the reported presence of cockroaches in the home. JF - Environmental Health Perspectives AU - Gehring, Ulrike AU - Triche, Elizabeth AU - van Strien, Robert T AU - Belanger, Kathleen AU - Holford, Theodore AU - Gold, Diane R AU - Jankun, Thomas Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 834 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOMESTIC ANIMALS KW - ALLERGIES KW - COCKROACHES KW - SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prediction+of+Residential+Pet+and+Cockroach+Allergen+Levels+Using+Questionnaire+Information&rft.au=Gehring%2C+Ulrike%3BTriche%2C+Elizabeth%3Bvan+Strien%2C+Robert+T%3BBelanger%2C+Kathleen%3BHolford%2C+Theodore%3BGold%2C+Diane+R%3BJankun%2C+Thomas&rft.aulast=Gehring&rft.aufirst=Ulrike&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=834&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 10 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOMESTIC ANIMALS; ALLERGIES; COCKROACHES; SURVEYS ER - TY - JOUR T1 - Lung Cancer Risk After Exposure to Polycyclic Aromatic Hydrocarbons: a Review and Meta-Analysis AN - 14698998; 10663793 JF - Environmental Health Perspectives AU - Armstrong, Ben AU - Hutchinson, Emma AU - Unwin, John AU - Fletcher, Tony Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 970 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - DOSE RESPONSE PROFILES KW - BENZO-A-PYRENE KW - POLYCYCLIC AROMATIC HYDROCARBON KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14698998?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lung+Cancer+Risk+After+Exposure+to+Polycyclic+Aromatic+Hydrocarbons%3A+a+Review+and+Meta-Analysis&rft.au=Armstrong%2C+Ben%3BHutchinson%2C+Emma%3BUnwin%2C+John%3BFletcher%2C+Tony&rft.aulast=Armstrong&rft.aufirst=Ben&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=970&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; DOSE RESPONSE PROFILES; BENZO-A-PYRENE; LITERATURE SURVEYS; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Recent Developments in Low-Level Lead Exposure and Intellectual Impairment in Children AN - 14698708; 10663795 AB - There is considerable uncertainty about the effects of low levels of lead exposure on children's health. Here, a review is presented of the issue, citing data from the literature on the sources of Pb exposure and current blood Pb levels. Eight recent cross-sectional studies are identified that have looked at the relationship between Pb concentrations and children's cognitive abilities. The evidence for lowered intellectual and cognitive ability in children exposed to Pb comes largely from prospective epidemiologic studies of cohorts in a number of cities in the US, Australia, and Yugoslavia. The findings support an association between childhood Pb exposure and subsequent cognitive impairment and extend the range of concern to children with lifetime average blood Pb levels 1 10 super(-6 )for daily consumption of greater than or equal to 17 g of soft-shell clam meat. JF - Environmental Health Perspectives AU - Gagnon, Fabien AU - Tremblay, Thierry AU - Rouette, Justine AU - Cartier, Jacques-Francois Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 883 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - FOOD CONSUMPTION PATTERNS KW - CANCER RISK KW - POLYCHLORINATED BIPHENYLS KW - FOOD CONTAMINATION KW - SHELLFISH KW - ARSENIC KW - CLAMS KW - ST LAWRENCE RIVER KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695960?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Chemical+Risks+Associated+with+Consumption+of+Shellfish+Harvested+on+the+North+Shore+of+the+St.+Lawrence+River%27s+Lower+Estuary&rft.au=Gagnon%2C+Fabien%3BTremblay%2C+Thierry%3BRouette%2C+Justine%3BCartier%2C+Jacques-Francois&rft.aulast=Gagnon&rft.aufirst=Fabien&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=883&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FOOD CONSUMPTION PATTERNS; SHELLFISH; CANCER RISK; POLYCHLORINATED BIPHENYLS; ARSENIC; CLAMS; ST LAWRENCE RIVER; FOOD CONTAMINATION ER - TY - JOUR T1 - Health and Environment Information Systems for Exposure and Disease Mapping, and Risk Assessment AN - 14695829; 10663796 AB - While overlaying maps of exposure and populations can define populations at risk, such linking is highly dependent on the accuracy of exposure assessment and the time elapsed between initial exposure and disease. The use of geographic information systems for exposure and disease mapping and risk assessment is outlined briefly. The main advantage of such an approach is the possibility of modeling exposure geographically so that individual exposure may be estimated without the need for time-consuming and extensive measurements. Two such systems, the UK Small Area Health Statistics Unit and the European Health and Environment Information System, are described. JF - Environmental Health Perspectives AU - Jarup, Lars Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 995 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - INFORMATION SYSTEMS, ENV KW - GEOGRAPHIC INFORMATION SYSTEMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695829?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Health+and+Environment+Information+Systems+for+Exposure+and+Disease+Mapping%2C+and+Risk+Assessment&rft.au=Jarup%2C+Lars&rft.aulast=Jarup&rft.aufirst=Lars&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=995&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 29 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; INFORMATION SYSTEMS, ENV; GEOGRAPHIC INFORMATION SYSTEMS ER - TY - JOUR T1 - Ultrafine Particle Deposition in Subjects with Asthma AN - 14695311; 10663559 AB - Sixteen men and women with mild asthma were exposed to ultrafine carbon particles for 2 h via mouthpiece, and deposition was measured during spontaneous breathing at rest and with exercise. Results revealed that the number deposition fraction increased as particle size decreased, and deposition increased with exercise. A significant correlation was observed between tidal volume and deposition fraction. The total number of particles retained in the lung was 74% greater in subjects with asthma than in healthy subjects. JF - Environmental Health Perspectives AU - Chalupa, David C AU - Morrow, Paul E AU - Oberdorster, Gunter AU - Utell, Mark J AU - Frampton, Mark W Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 879 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - ASTHMA KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695311?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Ultrafine+Particle+Deposition+in+Subjects+with+Asthma&rft.au=Chalupa%2C+David+C%3BMorrow%2C+Paul+E%3BOberdorster%2C+Gunter%3BUtell%2C+Mark+J%3BFrampton%2C+Mark+W&rft.aulast=Chalupa&rft.aufirst=David&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=879&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; ASTHMA; PARTICULATES ER - TY - JOUR T1 - Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. AN - 71900411; 14993220 AB - Ca2+-regulated exocytosis of lysosomes has been recognized recently as a ubiquitous process, important for the repair of plasma membrane wounds. Lysosomal exocytosis is regulated by synaptotagmin VII, a member of the synaptotagmin family of Ca2+-binding proteins localized on lysosomes. Here we show that Ca2+-dependent interaction of the synaptotagmin VII C(2)A domain with SNAP-23 is facilitated by syntaxin 4. Specific interactions also occurred in cell lysates between the plasma membrane t-SNAREs SNAP-23 and syntaxin 4 and the lysosomal v-SNARE TI-VAMP/VAMP7. Following cytosolic Ca2+ elevation, SDS-resistant complexes containing SNAP-23, syntaxin 4, and TI-VAMP/VAMP7 were detected on membrane fractions. Lysosomal exocytosis was inhibited by the SNARE domains of syntaxin 4 and TI-VAMP/VAMP7 and by cleavage of SNAP-23 with botulinum neurotoxin E, thereby functionally implicating these SNAREs in Ca2+-regulated exocytosis of conventional lysosomes. JF - The Journal of biological chemistry AU - Rao, Swathi K AU - Huynh, Chau AU - Proux-Gillardeaux, Veronique AU - Galli, Thierry AU - Andrews, Norma W AD - Section of Microbial Pathogenesis and Department of Cell Biology, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06511, USA. Y1 - 2004/05/07/ PY - 2004 DA - 2004 May 07 SP - 20471 EP - 20479 VL - 279 IS - 19 SN - 0021-9258, 0021-9258 KW - Antigens, CD KW - 0 KW - Bacterial Proteins KW - Calcium-Binding Proteins KW - Carrier Proteins KW - Lysosome-Associated Membrane Glycoproteins KW - Membrane Glycoproteins KW - Membrane Proteins KW - Nerve Tissue Proteins KW - Protein Isoforms KW - Qa-SNARE Proteins KW - Qb-SNARE Proteins KW - Qc-SNARE Proteins KW - R-SNARE Proteins KW - Recombinant Proteins KW - SNAP23 protein, human KW - SNARE Proteins KW - Streptolysins KW - Sybl1 protein, rat KW - Syt7 protein, rat KW - Vesicular Transport Proteins KW - streptolysin O KW - Synaptotagmins KW - 134193-27-4 KW - DNA KW - 9007-49-2 KW - beta-N-Acetylhexosaminidases KW - EC 3.2.1.52 KW - Calcium KW - SY7Q814VUP KW - Index Medicus KW - Animals KW - Electroporation KW - Calcium -- chemistry KW - Streptolysins -- pharmacology KW - Cell Survival KW - Calcium -- metabolism KW - Microscopy, Fluorescence KW - Rats KW - DNA -- chemistry KW - Flow Cytometry KW - Recombinant Proteins -- chemistry KW - Carrier Proteins -- metabolism KW - Dose-Response Relationship, Drug KW - beta-N-Acetylhexosaminidases -- chemistry KW - Precipitin Tests KW - Protein Binding KW - Antigens, CD -- metabolism KW - Cell Membrane -- metabolism KW - Protein Structure, Tertiary KW - Nerve Tissue Proteins -- physiology KW - Membrane Glycoproteins -- physiology KW - Membrane Proteins -- metabolism KW - Exocytosis KW - Nerve Tissue Proteins -- metabolism KW - Lysosomes -- metabolism KW - Membrane Glycoproteins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71900411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+biological+chemistry&rft.atitle=Identification+of+SNAREs+involved+in+synaptotagmin+VII-regulated+lysosomal+exocytosis.&rft.au=Rao%2C+Swathi+K%3BHuynh%2C+Chau%3BProux-Gillardeaux%2C+Veronique%3BGalli%2C+Thierry%3BAndrews%2C+Norma+W&rft.aulast=Rao&rft.aufirst=Swathi&rft.date=2004-05-07&rft.volume=279&rft.issue=19&rft.spage=20471&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+biological+chemistry&rft.issn=00219258&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-15 N1 - Date created - 2004-05-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The evidence for the safety of thiomersal in newborn and infant vaccines. AN - 71892510; 15121295 AB - While a number of studies remain to be completed, evidence is mounting that there is no demonstrable risk for infants immunized with vaccines containing thiomersal. Epidemiological studies in the US have shown no developmental or other central nervous system abnormalities resulting from exposure to vaccines containing thiomersal. During the initial evaluation of thiomersal in vaccines during 1999, the toxicological profile of ethyl mercury was unknown and presumed to be the same as that of methyl mercury. Enough evidence has accumulated since then to indicate the profiles of the two compounds are different in crucial aspects. To date, one study has measured blood levels of total mercury in vaccinated infants and reports only a brief low-level exposure with rapid excretion of mercury. It is not yet known for sure how much (if any) vaccine-derived ethyl mercury in the blood crosses the blood-brain barrier. For the most part, the use of thiomersal as a vaccine preservative has been convincingly shown to be safe. The scientific evidence is not yet sufficiently strong to provide the same level of assurance for thiomersal-containing vaccines for use in pregnant women or the premature or low birth weight infant. There is an increased sensitivity of the fetal brain to mercury whether it is ethyl or methyl mercury. While there is no evidence to support the contention, it is at least theoretically possible that very low birth weight premature infants may be at increased risk from thiomersal-containing vaccines. Until such time as the scientific evidence is to hand, thiomersal-free presentations of hepatitis B are to be preferred for the birth dose. Given the same levels of exposure, adults are at much lower levels of risk because of increased body mass. It is not possible to prove that thiomersal is completely safe-epidemiology can only quantify a risk, not prove its absence. JF - Vaccine AU - Clements, C John AD - Centre for International Health, The Macfarlane Burnet Institute for Medical Research and Public Health Ltd, GPO Box 2284, Commercial Road, Melbourne, Vic. 3004, Australia. john@clem.com.au Y1 - 2004/05/07/ PY - 2004 DA - 2004 May 07 SP - 1854 EP - 1861 VL - 22 IS - 15-16 SN - 0264-410X, 0264-410X KW - Ethylmercury Compounds KW - 0 KW - Methylmercury Compounds KW - Preservatives, Pharmaceutical KW - Vaccines KW - Thimerosal KW - 2225PI3MOV KW - Index Medicus KW - Infant, Very Low Birth Weight KW - Infant KW - Animals KW - Humans KW - Fishes KW - Adult KW - Infant, Newborn KW - Ethylmercury Compounds -- toxicity KW - Infant, Premature KW - Methylmercury Compounds -- toxicity KW - Female KW - Pregnancy KW - Vaccines -- adverse effects KW - Thimerosal -- adverse effects KW - Thimerosal -- toxicity KW - Preservatives, Pharmaceutical -- toxicity KW - Preservatives, Pharmaceutical -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71892510?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=The+evidence+for+the+safety+of+thiomersal+in+newborn+and+infant+vaccines.&rft.au=Clements%2C+C+John&rft.aulast=Clements&rft.aufirst=C&rft.date=2004-05-07&rft.volume=22&rft.issue=15-16&rft.spage=1854&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-18 N1 - Date created - 2004-05-03 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Vaccine. 2004 Dec 2;23(3):281-2 [15530668] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Do preserved foods increase prostate cancer risk? AN - 66652786; 15208621 AB - Preserved foods have been found in some studies to be associated with increased cancer risks. The possible relationship between preserved foods and prostate cancer was investigated in a case-control study in southeast China during 2001-2002 covering 130 histologically confirmed cases and 274 inpatient controls without malignant disease. The total amount of preserved food consumed was positively associated with cancer risk, the adjusted odds ratio being 7.05 (95% CI: 3.12-15.90) for the highest relative to the lowest quartile of intake. In particular, the consumption of pickled vegetables, fermented soy products, salted fish and preserved meats was associated with a significant increase in prostate cancer risk, all with a significant dose-response relationship. JF - British journal of cancer AU - Jian, L AU - Zhang, D H AU - Lee, A H AU - Binns, C W AD - School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia. Y1 - 2004/05/04/ PY - 2004 DA - 2004 May 04 SP - 1792 EP - 1795 VL - 90 IS - 9 SN - 0007-0920, 0007-0920 KW - Food Preservatives KW - 0 KW - Index Medicus KW - Risk Factors KW - Humans KW - Diet Surveys KW - Case-Control Studies KW - Aged KW - Male KW - China KW - Prostatic Neoplasms -- etiology KW - Food Preservatives -- adverse effects KW - Diet UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66652786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=British+journal+of+cancer&rft.atitle=Do+preserved+foods+increase+prostate+cancer+risk%3F&rft.au=Jian%2C+L%3BZhang%2C+D+H%3BLee%2C+A+H%3BBinns%2C+C+W&rft.aulast=Jian&rft.aufirst=L&rft.date=2004-05-04&rft.volume=90&rft.issue=9&rft.spage=1792&rft.isbn=&rft.btitle=&rft.title=British+journal+of+cancer&rft.issn=00070920&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-07-15 N1 - Date created - 2004-06-21 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Int J Cancer. 2000 May 1;86(3):421-4 [10760832] Med Sci Sports Exerc. 2000 Sep;32(9 Suppl):S498-504 [10993420] Int J Epidemiol. 2001 Apr;30(2):341-9 [11369740] Br J Cancer. 2002 Mar 4;86(5):712-7 [11875731] Cancer Epidemiol Biomarkers Prev. 2003 Mar;12(3):201-8 [12646508] Int J Cancer. 2004 Jan 1;108(1):130-5 [14618627] Lung Cancer. 1999 Sep;25(3):147-59 [10512125] Int J Cancer. 1994 Jul 15;58(2):197-202 [8026881] Neoplasma. 1996;43(1):61-3 [8843963] Int J Cancer. 1997;Suppl 10:2-6 [9209011] Cancer Res. 1997 Nov 15;57(22):5077-85 [9371506] Int J Cancer. 1998 May 29;76(5):659-64 [9610722] Br J Cancer. 1999 Jun;80(7):1107-13 [10362125] J Natl Cancer Inst. 1990 Jun 6;82(11):915-26 [2342126] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Measurement and prediction of METs during household activities in 35- to 45-year-old females AN - 954615743; 14081782 AB - This study determined whether four self-paced household tasks, conducted in the subjects' homes and a standardised laboratory environment, were performed at a moderate intensity [3-6 metabolic equivalents (METs)] in a representative sample of thirty-six 35- to 45-year-old females. Energy expenditure was also predicted via indirect methods. Self-paced energy expenditure during sweeping, window cleaning, vacuuming and mowing was measured using the Douglas bag technique. Heart rate, respiratory frequency, Computer Science Applications (CSA) movement counts (hip and wrist), Borg rating of perceived exertion and Quetelet's index were also recorded as potential predictors of energy expenditure. While the four activities were performed at mean intensities greater than or equal to 3.0 METs in both the home and laboratory, all comparisons between these two environments were statistically significant (P<0.001). The 95% confidence intervals (CIs) for the home and laboratory prediction equations were plus or minus 1.1 METs and plus or minus 1.0 MET, respectively. These data suggest that the aforementioned household chores can contribute to the 30min.day super(-1) of moderate-intensity activity required to confer health benefits. However, the substantial between-subject variability in energy expenditure resulted in some persons performing these tasks at a light intensity (<3.0 METs). The significant MET differences between the home and laboratory emphasise the effects of 'environment and terrain' and the 'mental approach to a task' on self-paced energy expenditure. Considering the means for the five activities ranged from 3.1 METs to 6.0 METs, the 95% CIs for the regression equations lack predictive precision. JF - European Journal of Applied Physiology AU - Brooks, Anthony G AU - Withers, Robert T AU - Gore, Christopher J AU - Vogler, Andrew J AU - Plummer, John AU - Cormack, John AD - Exercise Physiology Laboratory, School of Education, Flinders University, G.P.O. Box 2100, Adelaide, South Australia, Australia, 5001, bob.withers@flinders.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 638 EP - 648 PB - Springer-Verlag, P.O. Box 2485 Secaucus NJ 07096-2485 USA VL - 91 IS - 5-6 SN - 1439-6319, 1439-6319 KW - Physical Education Index KW - Energy cost KW - Measurement KW - Home KW - Statistics KW - Heart rate KW - Baseball KW - Activities KW - Wrists KW - Professional sports KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954615743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Applied+Physiology&rft.atitle=Measurement+and+prediction+of+METs+during+household+activities+in+35-+to+45-year-old+females&rft.au=Brooks%2C+Anthony+G%3BWithers%2C+Robert+T%3BGore%2C+Christopher+J%3BVogler%2C+Andrew+J%3BPlummer%2C+John%3BCormack%2C+John&rft.aulast=Brooks&rft.aufirst=Anthony&rft.date=2004-05-01&rft.volume=91&rft.issue=5-6&rft.spage=638&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Applied+Physiology&rft.issn=14396319&rft_id=info:doi/10.1007%2Fs00421-003-1018-9 LA - English DB - Physical Education Index N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - Energy cost; Measurement; Statistics; Home; Heart rate; Baseball; Wrists; Activities; Professional sports DO - http://dx.doi.org/10.1007/s00421-003-1018-9 ER - TY - JOUR T1 - Osteogenic Protein-1 inhibits matrix depletion in a hyaluronan hexasaccharide-induced model of osteoarthritis. AN - 71849721; 15094136 AB - To examine the capacity of recombinant osteogenic protein-1 (OP-1) to inhibit the cartilage extracellular matrix damage that follows treatment with hyaluronan hexasaccharides (HA6). The effects of OP-1 were examined on isolated human chondrocytes grown in alginate beads as well as articular cartilage slices treated with hyaluronan hexasaccharides. Changes in the relative expression of messenger RNA for hyaluronan synthase- 2, aggrecan and CD44 were determined by competitive quantitative reverse transcriptase-polymerase chain reaction. Cartilage proteoglycan biosynthesis was examined by a (35)S-sulfate incorporation assay. Cell-associated matrix of human chondrocytes was visualized by the use of particle exclusion assay, and alcian blue staining. Cartilage slices were examined for accumulation of proteoglycan by Safranin-O, and hyaluronan by a specific biotinylated probe. Combined OP-1 and HA6 treatment resulted in enhanced expression of mRNA for aggrecan and HAS-2, compared to the treatment with HA6 only. This increased expression of aggrecan mRNA was paralleled by an increased synthesis of cartilage proteoglycan especially retained in the cell-associated matrix. Co-treatment with OP-1 inhibited the HA6-induced depletion of cell-associated matrices as well as HA6-induced depletion of hyaluronan and proteoglycan within cartilage tissue slices. These results demonstrate that OP-1 can abrogate the catabolic events associated with a HA6-induced matrix depletion model of osteoarthritis. The mRNA levels of two major cartilage extracellular matrix components, aggrecan and hyaluronan synthase-2 are enhanced above values obtained by either OP-1 or HA6 treatments alone. JF - Osteoarthritis and cartilage AU - Nishida, Yoshihiro AU - Knudson, Cheryl B AU - Knudson, Warren AD - Department of Biochemistry, Rush Medical College, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, USA. Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 374 EP - 382 VL - 12 IS - 5 SN - 1063-4584, 1063-4584 KW - Aggrecans KW - 0 KW - Antigens, CD44 KW - BMP7 protein, human KW - Bone Morphogenetic Protein 7 KW - Bone Morphogenetic Proteins KW - Extracellular Matrix Proteins KW - Lectins, C-Type KW - Proteins KW - Proteoglycans KW - Transforming Growth Factor beta KW - RNA KW - 63231-63-0 KW - Hyaluronic Acid KW - 9004-61-9 KW - Transferases KW - EC 2.- KW - HAS2 protein, human KW - EC 2.4.1.- KW - Glucuronosyltransferase KW - EC 2.4.1.17 KW - hyaluronan synthase KW - EC 2.4.1.212 KW - ACVR1 protein, human KW - EC 2.7.11.30 KW - Activin Receptors, Type I KW - Index Medicus KW - Proteoglycans -- biosynthesis KW - Humans KW - Aged KW - Glucuronosyltransferase -- metabolism KW - Antigens, CD44 -- metabolism KW - Transferases -- metabolism KW - Extracellular Matrix Proteins -- metabolism KW - Proteoglycans -- metabolism KW - RNA -- metabolism KW - Cells, Cultured KW - Adult KW - Bone Morphogenetic Proteins -- metabolism KW - Middle Aged KW - Transforming Growth Factor beta -- metabolism KW - Chondrocytes -- metabolism KW - Proteins -- pharmacology KW - Extracellular Matrix -- drug effects KW - Cartilage, Articular -- metabolism KW - Osteoarthritis -- metabolism KW - Extracellular Matrix -- metabolism KW - Hyaluronic Acid -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71849721?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Osteoarthritis+and+cartilage&rft.atitle=Osteogenic+Protein-1+inhibits+matrix+depletion+in+a+hyaluronan+hexasaccharide-induced+model+of+osteoarthritis.&rft.au=Nishida%2C+Yoshihiro%3BKnudson%2C+Cheryl+B%3BKnudson%2C+Warren&rft.aulast=Nishida&rft.aufirst=Yoshihiro&rft.date=2004-05-01&rft.volume=12&rft.issue=5&rft.spage=374&rft.isbn=&rft.btitle=&rft.title=Osteoarthritis+and+cartilage&rft.issn=10634584&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-02 N1 - Date created - 2004-04-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The Australian Air Quality Forecasting System. Part II: Case Study of a Sydney 7-Day Photochemical Smog Event AN - 28453315; 200504-31-07927 (CE); 05988790 (EN); A05-45-14032 (AH) AB - The performance of the Australian Air Quality Forecasting System (AAQFS) is examined by means of a case study of a 7-day photochemical smog event in the Sydney region. This was the worst smog event for the 2000/ 01 oxidant season, and, because of its prolonged nature, it provided the opportunity to demonstrate the ability of AAQFS to forecast situations involving recirculation of precursors and remnant ozone, fumigation, and complex meteorological dynamics. The forecasting system was able to successfully predict high values of ozone, although at times the peak concentrations for the inland stations were underestimated. The dynamics for the Sydney region require a sensitive balance between the synoptic and mesoscale flows. Often high concentrations of ozone were advected inland by the sea breeze. On two occasions the system forecast a synoptic flow that was too strong, which blocked the inland advancement of the sea breeze. The peak ozone forecasts were underpredicted at the inland stations on those occasions. An examination of possible factors causing forecast errors has indicated that the AAQFS is more sensitive to errors in the meteorological conditions, rather than in the emissions or chemical mechanism in the Sydney region. JF - Journal of Applied Meteorology AU - Hess, G D AU - Tory, K J AU - Cope, M E AU - Lee, S AU - Puri, K AU - Manins, P C AU - Young, M AD - Corresponding author address: G. D. Hess, Bureau of Meteorology Research Centre, GPO Box 1289K, Melbourne VIC 3001, Australia. hess@bom.gov.au PY - 2004 SP - 663 EP - 679 PB - American Meteorological Society, 45 Beacon St , Boston, MA, 02108, USA, [mailto:amsinfo@ametsoc.org], [URL:http://www.ametsoc.org/ams] VL - 43 IS - 5 SN - 0894-8763, 0894-8763 KW - Civil Engineering (CE); Environmental Engineering (EN); Aerospace & High Technology (AH) KW - Air pollution KW - Cities KW - Mesoscale phenomena KW - Photochemical reactions KW - Meteorological parameters KW - Ozone KW - Smog KW - Air quality KW - Error detection KW - Sea breeze KW - Oxidizing agents KW - Australia KW - Article KW - EE 20:Air Pollution: Monitoring, Control & Remediation (EN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/28453315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=The+Australian+Air+Quality+Forecasting+System.+Part+II%3A+Case+Study+of+a+Sydney+7-Day+Photochemical+Smog+Event&rft.au=Hess%2C+G+D%3BTory%2C+K+J%3BCope%2C+M+E%3BLee%2C+S%3BPuri%2C+K%3BManins%2C+P+C%3BYoung%2C+M&rft.aulast=Hess&rft.aufirst=G&rft.date=2004-05-01&rft.volume=43&rft.issue=5&rft.spage=663&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2F2094.1 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-11-11 DO - http://dx.doi.org/10.1175/2094.1 ER - TY - JOUR T1 - The Australian Air Quality Forecasting System. Part III: Case Study of a Melbourne 4-Day Photochemical Smog Event AN - 28428246; 200504-31-07928 (CE); 05988791 (EN); A05-45-14033 (AH) AB - A 4-day photochemical smog event in the Melbourne, Victoria, Australia, region (6-9 March 2001) is examined to assess the performance of the Australian Air Quality Forecasting System (AAQFS). Although peak ozone concentrations measured during this period did not exceed the 1-h national air quality standard of 100 ppb, elevated maximum ozone concentrations in the range of 50-80 ppb were recorded at a number of monitoring stations on all four days. These maximum values were in general very well forecast by the AAQFS. On all but the third day the system predicted the advection of ozone precursors over Port Phillip (the adjacent bay) during the morning, where, later in the day, relatively high ozone concentrations developed. The ozone was advected back inland by bay and sea breezes. On the third day, a southerly component to the background wind direction prevented the precursor drainage over the bay, and the characteristic ozone cycle was disrupted. The success of the system's ability to predict peak ozone at individual monitoring stations was largely dependent on the direction and penetration of the sea and bay breezes, which in turn were dependent on the delicate balance between these winds and the opposing synoptic flow. JF - Journal of Applied Meteorology AU - Tory, K J AU - Cope, M E AU - Hess, G D AU - Lee, S AU - Puri, K AU - Manins, P C AU - Wong, N AD - Bureau of Meteorology Research Centre, GPO Box 1289K, Melbourne, VIC 3001, Australia tory@bom.gov.au PY - 2004 SP - 680 EP - 695 PB - American Meteorological Society, 45 Beacon St , Boston, MA, 02108, USA, [mailto:amsinfo@ametsoc.org], [URL:http://www.ametsoc.org/ams] VL - 43 IS - 5 SN - 0894-8763, 0894-8763 KW - Civil Engineering (CE); Environmental Engineering (EN); Aerospace & High Technology (AH) KW - Air pollution KW - Synoptic meteorology KW - Diurnal variations KW - Ozone KW - Air quality KW - Smog KW - Weather forecasting KW - Sea breezes KW - Wind direction KW - Drainage KW - Article KW - EE 20:Air Pollution: Monitoring, Control & Remediation (EN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/28428246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=The+Australian+Air+Quality+Forecasting+System.+Part+III%3A+Case+Study+of+a+Melbourne+4-Day+Photochemical+Smog+Event&rft.au=Tory%2C+K+J%3BCope%2C+M+E%3BHess%2C+G+D%3BLee%2C+S%3BPuri%2C+K%3BManins%2C+P+C%3BWong%2C+N&rft.aulast=Tory&rft.aufirst=K&rft.date=2004-05-01&rft.volume=43&rft.issue=5&rft.spage=680&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2F2092.1 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-11-11 DO - http://dx.doi.org/10.1175/2092.1 ER - TY - JOUR T1 - Metals in Airborne Particulate Matter in Downtown Rio de Janeiro, Brazil AN - 21047865; 5982356 AB - Without abstract. JF - Bulletin of Environmental Contamination and Toxicology AU - Quiterio, S L AU - Escaleira, V AU - Sousa, CRS AU - Maia, LFPG AU - Arbilla, G AD - Physical Chemistry Department, Federal University of Rio de Janeiro, CT, Building A, Room 408, 21949-900, Cidade Universitaria, Rio de Janeiro, RJ, Brazil Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 916 EP - 922 PB - Springer-Verlag, Life Science Journals, 175 Fifth Ave. New York NY 10010 USA, [mailto:orders@springer-ny.com], [URL:http://www.springer-ny.com/] VL - 72 IS - 5 SN - 0007-4861, 0007-4861 KW - Toxicology Abstracts; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Brazil, Rio de Janeiro KW - Metals KW - Atmospheric pollution KW - Airborne particulates KW - Metals in aerosols KW - Air quality KW - Particulates KW - Chemical composition of aerosols KW - Urban areas KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21047865?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+Environmental+Contamination+and+Toxicology&rft.atitle=Metals+in+Airborne+Particulate+Matter+in+Downtown+Rio+de+Janeiro%2C+Brazil&rft.au=Quiterio%2C+S+L%3BEscaleira%2C+V%3BSousa%2C+CRS%3BMaia%2C+LFPG%3BArbilla%2C+G&rft.aulast=Quiterio&rft.aufirst=S&rft.date=2004-05-01&rft.volume=72&rft.issue=5&rft.spage=916&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+Environmental+Contamination+and+Toxicology&rft.issn=00074861&rft_id=info:doi/10.1007%2Fs00128-004-0331-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-02-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Metals; Airborne particulates; Atmospheric pollution; Air quality; Metals in aerosols; Chemical composition of aerosols; Particulates; Urban areas; Brazil, Rio de Janeiro DO - http://dx.doi.org/10.1007/s00128-004-0331-2 ER - TY - JOUR T1 - Emissions from a vehicle fitted to operate on either petrol or compressed natural gas AN - 19963287; 6906261 AB - The purpose of this work was to evaluate the physical and chemical properties of emission products from a six-cylinder sedan car under a variety of operating conditions, before and after it has been converted to compressed natural gas (CNG) fuel. The specific focus of the measurements was on emission levels and characteristics of ultra fine particles and the emission levels together with the emissions of gaseous pollutants for a range of operating conditions before and up to 3 months after the vehicle was converted are presented and discussed in the paper. The investigations showed that converting a petrol operating vehicle to CNG has the potential of reducing some of the emissions and thus risks, while it does not appear to have an impact on others. In particular there was no statistically significant change in the emission of particles for the vehicle operating on petrol, before the conversion, compared to the emissions for the vehicle operating on CNG, after the conversion. There was a significant lowering of emissions of total polycyclic aromatic hydrocarbons and formaldehyde when the vehicle was operated on CNG, and a reduction of global warming potential was also observed when the vehicle was run on CNG, but the later gain is only at high vehicle speeds/loads, and would thus have to be considered in view of traffic and transport models for the region (in these models vehicle speed is an important parameter). JF - Science of the Total Environment AU - Ristovski, Z AU - Morawska, L AU - Ayoko, G A AU - Johnson, G AU - Gilbert, D AU - Greenaway, C AD - International Laboratory for Air Quality and Health, Queensland University of Technology, G.P.O. 2434, Brisbane, Qld 4001, Australia, l.morawska@qut.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 179 EP - 194 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 323 IS - 1-3 SN - 0048-9697, 0048-9697 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts; Risk Abstracts KW - Author Keywords: Emissions KW - Natural gas KW - Global warming potential KW - Polycyclic aromatic hydrocarbons KW - Fuels KW - Statistical analysis KW - Velocity KW - Formaldehyde KW - Emission control KW - Particulates KW - Atmospheric pollution by motor vehicles KW - Polycyclic aromatic hydrocarbon emissions KW - Gaseous pollutants KW - Emission measurements KW - Global warming KW - Automotive exhaust emissions KW - Air pollution measurements KW - P 0000:AIR POLLUTION KW - M2 551.588:Environmental Influences (551.588) KW - R2 23050:Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19963287?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Science+of+the+Total+Environment&rft.atitle=Emissions+from+a+vehicle+fitted+to+operate+on+either+petrol+or+compressed+natural+gas&rft.au=Ristovski%2C+Z%3BMorawska%2C+L%3BAyoko%2C+G+A%3BJohnson%2C+G%3BGilbert%2C+D%3BGreenaway%2C+C&rft.aulast=Ristovski&rft.aufirst=Z&rft.date=2004-05-01&rft.volume=323&rft.issue=1-3&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=Science+of+the+Total+Environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2003.10.023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Gaseous pollutants; Statistical analysis; Global warming; Atmospheric pollution by motor vehicles; Polycyclic aromatic hydrocarbon emissions; Polycyclic aromatic hydrocarbons; Fuels; Emission measurements; Formaldehyde; Velocity; Emission control; Particulates; Automotive exhaust emissions; Natural gas; Air pollution measurements DO - http://dx.doi.org/10.1016/j.scitotenv.2003.10.023 ER - TY - JOUR T1 - Sexual Selection Under Scramble Competition: Mate Location and Mate Choice in the Eucalypt Leaf Beetle Chrysophtharta agricola (Chapuis) in the Field AN - 18058900; 6024063 AB - For males of many species, the number of offspring sired can depend on the number of females mated. While pre- and postcopulatory choice by females can affect the outcome of potential mate encounters, mate location is a necessary prerequisite to any possible courtship and subsequent mating. Mate location of Chrysophtharta agricola in the field was examined using sticky traps baited with sexually receptive conspecific beetles. More beetles were caught on traps baited with conspecific beetles of either sex than on control traps that contained foliage only. Furthermore, 94% of beetles captured on control traps were males, indicating that the mating system of Chrysophtharta agricola can be labeled prolonged searching scramble competition polyandry, in which receptive females are evenly dispersed spatially and temporally, and males search competitively for them. Operational sex ratios were 1:1 throughout the season. By sampling paired and unpaired beetles in the field, we found that beetles generally did not select mates based on body size. Furthermore, neither sex mated preferentially with partners that were uninfected by parasitic mites or with beetles of the same generation. In the absence of postcopulatory female choice, the ability of males to locate females may therefore be the most important trait in determining male mating success. JF - Journal of Insect Behavior AU - Nahrung, H F AU - Allen, G R AD - CRC for Sustainable Production Forestry, GPO Box 252-12, Hobart, and School of Agricultural Science, The University of Tasmania, GPO Box 252-54, Hobart, Tasmania 7001, Australia, h.nahrung@qut.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 353 EP - 366 PB - Kluwer Academic Publishers VL - 17 IS - 3 SN - 0892-7553, 0892-7553 KW - Coleoptera KW - Leaf beetles KW - Ecology Abstracts; Animal Behavior Abstracts; Entomology Abstracts KW - Polyandry KW - Sexual selection KW - Chrysophtharta agricola KW - Mate selection KW - Competition KW - Chrysomelidae KW - D 04659:Insects KW - Y 25423:Insects KW - Z 05192:Reproductive behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18058900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Insect+Behavior&rft.atitle=Sexual+Selection+Under+Scramble+Competition%3A+Mate+Location+and+Mate+Choice+in+the+Eucalypt+Leaf+Beetle+Chrysophtharta+agricola+%28Chapuis%29+in+the+Field&rft.au=Nahrung%2C+H+F%3BAllen%2C+G+R&rft.aulast=Nahrung&rft.aufirst=H&rft.date=2004-05-01&rft.volume=17&rft.issue=3&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Journal+of+Insect+Behavior&rft.issn=08927553&rft_id=info:doi/10.1023%2FB%3AJOIR.0000031536.59988.0d LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Chrysophtharta agricola; Chrysomelidae; Competition; Sexual selection; Mate selection; Polyandry DO - http://dx.doi.org/10.1023/B:JOIR.0000031536.59988.0d ER - TY - JOUR T1 - Biogeochemical marine ecosystem models I: IGBEM--a model of marine bay ecosystems AN - 18056179; 5887208 AB - The Integrated Generic Bay Ecosystem Model (IGBEM) is presented. It is a coupled physical transport-biogeochemical process model constructed as a basis to explore the effects of model structure and complexity. The foundations for the model are two existing models, the European Regional Seas Ecosystem Model II (ERSEM II) and the Port Phillip Bay Integrated Model (PPBIM). Additional functional groups (such as benthic herbivorous invertebrates) and modules (dealing with sediment chemistry and mixing) have been incorporated or modified to ensure a more complete representation of temperate bay ecosystems and their processes, and a seamless amalgam of ERSEM II and PPBIM. The standard form of the entire model compares well with real ecosystems, such as Port Phillip Bay in Australia, and conforms to general ecological checkpoints such as the expected Sheldon Spectrum and Monbet's relationship between chlorophyll a and dissolved inorganic nitrogen. The model also produces spatial zonation and long-term cycles characteristic of natural systems. Despite the model taking a generalised biomass per functional group form, it captures well the system dynamics and allows for exploration of the effects of ecological driving forces such as predation and competition. JF - Ecological Modelling AU - Fulton, E A AU - Smith, ADM AU - Johnson, C R AD - CSIRO Division of Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, beth.fulton@csiro.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 267 EP - 307 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 174 IS - 3 SN - 0304-3800, 0304-3800 KW - ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Chlorophylls KW - Ecosystems KW - Predation KW - Nutrient cycles KW - Ecosystem models KW - PSE, Australia, Victoria, Port Phillip Bay KW - Interspecific relationships KW - Marine environment KW - Transport processes KW - Biotic factors KW - Competition KW - Temperate zones KW - Bays KW - Modelling KW - Abiotic factors KW - Marine KW - Sediment chemistry KW - Biogeochemical cycle KW - Biogeochemistry KW - Energy flow KW - Zoobenthos KW - Bay dynamics KW - Plankton KW - Nitrogen KW - Benthos KW - Q1 08482:Ecosystems and energetics KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18056179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Biogeochemical+marine+ecosystem+models+I%3A+IGBEM--a+model+of+marine+bay+ecosystems&rft.au=Fulton%2C+E+A%3BSmith%2C+ADM%3BJohnson%2C+C+R&rft.aulast=Fulton&rft.aufirst=E&rft.date=2004-05-01&rft.volume=174&rft.issue=3&rft.spage=267&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.09.027 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Sediment chemistry; Chlorophylls; Ecosystems; Biogeochemistry; Biogeochemical cycle; Predation; Nutrient cycles; Energy flow; Interspecific relationships; Transport processes; Zoobenthos; Biotic factors; Bay dynamics; Competition; Temperate zones; Plankton; Abiotic factors; Benthos; Modelling; Nitrogen; Bays; Marine environment; Ecosystem models; PSE, Australia, Victoria, Port Phillip Bay; Marine DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.09.027 ER - TY - JOUR T1 - Enhanced vigilance in groups in Egernia stokesii, a lizard with stable social aggregations AN - 18019044; 5967224 AB - The Australian gidgee skink Egernia stokesii is unusual among lizards in that it maintains stable social aggregations of related individuals. Experiments were conducted to investigate whether lizards living in groups gained benefits from the collective detection of approaching threats. In captive colonies, lizards living in a group detected an approaching threat earlier than lizards alone, and lizards basking in a group spent more time in a non-vigilant, eyes-closed, state than lizards alone. These results imply that individuals in this species gain from the enhanced vigilance associated with group membership. Since many juveniles remain within their natal groups, group vigilance may enhance inclusive fitness. JF - Journal of Zoology AU - Lanham, E J AU - Bull, C M AD - School of Biological Sciences, Flinders University of South Australia, GPO Box 2100, Adelaide, SA 5001, Australia, michael.bull@flinders.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 95 EP - 99 VL - 263 IS - 1 SN - 0952-8369, 0952-8369 KW - Animal Behavior Abstracts; Ecology Abstracts KW - Fitness KW - Social organization KW - Group size KW - Egernia stokesii KW - Vigilance KW - Y 25504:Vertebrates (excluding fish, birds & mammals) KW - D 04670:Reptiles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18019044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Zoology&rft.atitle=Enhanced+vigilance+in+groups+in+Egernia+stokesii%2C+a+lizard+with+stable+social+aggregations&rft.au=Lanham%2C+E+J%3BBull%2C+C+M&rft.aulast=Lanham&rft.aufirst=E&rft.date=2004-05-01&rft.volume=263&rft.issue=1&rft.spage=95&rft.isbn=&rft.btitle=&rft.title=Journal+of+Zoology&rft.issn=09528369&rft_id=info:doi/10.1017%2FS0952836904004923 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Egernia stokesii; Social organization; Fitness; Group size; Vigilance DO - http://dx.doi.org/10.1017/S0952836904004923 ER - TY - JOUR T1 - Testing density-dependent groundwater models: two-dimensional steady state unstable convection in infinite, finite and inclined porous layers AN - 17983787; 5906287 AB - This study proposes the use of several problems of unstable steady state convection with variable fluid density in a porous layer of infinite horizontal extent as two-dimensional (2-D) test cases for density-dependent groundwater flow and solute transport simulators. Unlike existing density-dependent model benchmarks, these problems have well-defined stability criteria that are determined analytically. These analytical stability indicators can be compared with numerical model results to test the ability of a code to accurately simulate buoyancy driven flow and diffusion. The basic analytical solution is for a horizontally infinite fluid-filled porous layer in which fluid density decreases with depth. The proposed test problems include unstable convection in an infinite horizontal box, in a finite horizontal box, and in an infinite inclined box. A dimensionless Rayleigh number incorporating properties of the fluid and the porous media determines the stability of the layer in each case. Testing the ability of numerical codes to match both the critical Rayleigh number at which convection occurs and the wavelength of convection cells is an addition to the benchmark problems currently in use. The proposed test problems are modelled in 2-D using the SUTRA [SUTRA--A model for saturated-unsaturated variable-density ground-water flow with solute or energy transport. US Geological Survey Water-Resources Investigations Report, 02-4231, 2002. 250 p] density-dependent groundwater flow and solute transport code. For the case of an infinite horizontal box, SUTRA results show a distinct change from stable to unstable behaviour around the theoretical critical Rayleigh number of 4[pi] and the simulated wavelength of unstable convection agrees with that predicted by the analytical solution. The effects of finite layer aspect ratio and inclination on stability indicators are also tested and numerical results are in excellent agreement with theoretical stability criteria and with numerical results previously reported in traditional fluid mechanics literature. JF - Advances in Water Resources AU - Weatherill, D AU - Simmons, C T AU - Voss, C I AU - Robinson, NI AD - School of Chemistry, Physics and Earth Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia, douglas.weatherill@flinders.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 547 EP - 562 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 27 IS - 5 SN - 0309-1708, 0309-1708 KW - Water Resources Abstracts; Aqualine Abstracts KW - Convection KW - Porous Media KW - Model Testing KW - Model Studies KW - Hydrologic Models KW - Groundwater Data KW - AQ 00001:Water Resources and Supplies KW - SW 0840:Groundwater UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17983787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Water+Resources&rft.atitle=Testing+density-dependent+groundwater+models%3A+two-dimensional+steady+state+unstable+convection+in+infinite%2C+finite+and+inclined+porous+layers&rft.au=Weatherill%2C+D%3BSimmons%2C+C+T%3BVoss%2C+C+I%3BRobinson%2C+NI&rft.aulast=Weatherill&rft.aufirst=D&rft.date=2004-05-01&rft.volume=27&rft.issue=5&rft.spage=547&rft.isbn=&rft.btitle=&rft.title=Advances+in+Water+Resources&rft.issn=03091708&rft_id=info:doi/10.1016%2Fj.advwatres.2004.01.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Convection; Hydrologic Models; Porous Media; Groundwater Data; Model Testing; Model Studies DO - http://dx.doi.org/10.1016/j.advwatres.2004.01.003 ER - TY - JOUR T1 - Evaluation of the Effectiveness of Court-Ordered Fisheries Management Policies AN - 17851959; 5962709 AB - Within the 1836 Treaty waters of the Laurentian Great Lakes, fisheries allocation and management between Native and state-licensed fishers was guided by a court-ordered policy, the 1985 Consent Order. This policy was created to promote rehabilitation of lake trout (Salvelinus namaycush), reduce social conflict, and provide a framework for joint fisheries management. Expiration of the order led to creation of a replacement policy, the 2000 Consent Decree. To assess effectiveness of the 1985 Consent Order and perceptions of the 2000 Consent Decree, we conducted 46 interviews with members of pertinent stakeholder groups and their representatives. Results indicated that most stakeholders believed the 1985 Consent Order was insufficient to promote lake trout rehabilitation. Most respondents outside the Grand Traverse Bay area perceived that social conflict decreased under this policy. Tribal and DNR biologists and representatives believed fisheries management improved and became more cooperative. Many biologists and representatives anticipated the 2000 Consent Decree would be more effective at promoting lake trout rehabilitation and cooperative joint management. In contrast to some fishers, these respondents did not expect social conflict under this policy. Results indicated that court-ordered policies should allocate fisheries to provide economic opportunities and incorporate institutionalized, collaborative management processes. JF - Fisheries AU - Cimo, L F AU - Dobson, T Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 10 EP - 18 VL - 29 IS - 5 SN - 0363-2415, 0363-2415 KW - Lake trout KW - Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Stakeholders KW - Policies KW - Social aspects KW - Fishery regulations KW - Freshwater KW - USA, Michigan, Michigan L., Grand Traverse Bay KW - Fishery policy KW - Lakes KW - Fishery management KW - Inland fisheries KW - Environmental restoration KW - Cooperatives KW - Salvelinus namaycush KW - Disputes KW - M3 1130:Water KW - Q1 08604:Stock assessment and management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17851959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fisheries&rft.atitle=Evaluation+of+the+Effectiveness+of+Court-Ordered+Fisheries+Management+Policies&rft.au=Cimo%2C+L+F%3BDobson%2C+T&rft.aulast=Cimo&rft.aufirst=L&rft.date=2004-05-01&rft.volume=29&rft.issue=5&rft.spage=10&rft.isbn=&rft.btitle=&rft.title=Fisheries&rft.issn=03632415&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Policies; Fishery management; Inland fisheries; Fishery regulations; Disputes; Fishery policy; Stakeholders; Lakes; Cooperatives; Environmental restoration; Social aspects; Salvelinus namaycush; USA, Michigan, Michigan L., Grand Traverse Bay; Freshwater ER - TY - JOUR T1 - The determination of trace metal pollutants in environmental matrices using ion chromatography AN - 17210466; 6904719 AB - A review is presented detailing the development of ion chromatography (IC) as a selective analytical tool for the determination of toxic metals and their organic species in many environmental sample matrices. A brief outline of ion chromatographic principles, together with an overview of the stationary phases used to separate metals, namely ion exchangers, modified ion pair sorbents and chelating ion exchangers, and the methods for detecting metal ions including hyphenation with spectroscopy and sample preparation schemes are also given, prior to a critical examination of developed methods for various metals including arsenic, chromium, cadmium, lead, mercury, beryllium, aluminium and uranium since 1990. JF - Environment International AU - Shaw, Matthew J AU - Haddad, Paul R AD - Australian Centre for Research on Separation Science, School of Chemistry, University of Tasmania, GPO Box 252-75, Private Bag 75, Hobart 7001, Tasmania, Australia, Paul.Haddad@utas.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 403 EP - 431 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 30 IS - 3 SN - 0160-4120, 0160-4120 KW - Pollution Abstracts KW - Author Keywords: Ion chromatography KW - Chelation KW - Metal ions KW - Hyphenation KW - ICP-MS KW - Post-column reaction KW - Environmental monitoring KW - Arsenic KW - Chromium KW - Chromatography KW - Heavy metals KW - Lead KW - Monitoring methods KW - Reviews KW - Uranium KW - Beryllium KW - Aluminum KW - Mercury KW - Cadmium KW - Ion exchange KW - Chemical analysis KW - Trace metals KW - P 9000:ENVIRONMENTAL ACTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17210466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environment+International&rft.atitle=The+determination+of+trace+metal+pollutants+in+environmental+matrices+using+ion+chromatography&rft.au=Shaw%2C+Matthew+J%3BHaddad%2C+Paul+R&rft.aulast=Shaw&rft.aufirst=Matthew&rft.date=2004-05-01&rft.volume=30&rft.issue=3&rft.spage=403&rft.isbn=&rft.btitle=&rft.title=Environment+International&rft.issn=01604120&rft_id=info:doi/10.1016%2Fj.envint.2003.09.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-09-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Arsenic; Chromium; Heavy metals; Chromatography; Lead; Monitoring methods; Uranium; Reviews; Aluminum; Beryllium; Mercury; Cadmium; Chemical analysis; Ion exchange; Trace metals DO - http://dx.doi.org/10.1016/j.envint.2003.09.009 ER - TY - JOUR T1 - Does greater night-time, rather than constant, warming alter growth of managed pasture under under ambient and elevated atmospheric CO sub(2)? AN - 17099340; 6636326 AB - This study examined the effects of warming, elevated atmospheric CO sub(2) and cutting regimen on the growth of Phalaris aquatica cv. Holdfast swards. Six temperature gradient tunnels (TGT) were used to manipulate both air temperature and atmospheric CO sub(2) concentrations (ambient and 750 ppm). Within each tunnel, there were three temperature treatments: no warming, constant warming of +3.0 degree C and a daytime warming of 2.2 degree C combined with a night-time warming of 4.0 degree C and two defoliation frequencies. Averaged across 20 months of growth, there was a positive effect of elevated atmospheric CO sub(2) (+11%), no effect of either warming treatment and a negative effect of frequent cutting (-19%) on total above ground biomass production. The responses to all treatments, however, were strongly seasonal. Positive responses to CO sub(2) were statistically significant only in the spring, when plant growth was strongest. No evidence was found that high night-time warming had different effects on plant growth and plant responses to elevated atmospheric CO sub(2), than constant warming. JF - New Phytologist AU - Volder, A AU - Edwards, E J AU - Evans, J R AU - Robertson, B C AU - Schortemeyer, M AU - Gifford, R M AD - Cooperative Research Centre for Greenhouse Accounting, GPO Box 475, Canberra, ACT 2601, Australia; CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, Astrid.Volder@csiro.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 397 EP - 411 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 162 IS - 2 SN - 0028-646X, 0028-646X KW - Ecology Abstracts KW - Temperature effects KW - Daytime KW - Phalaris aquatica KW - Statistical analysis KW - Defoliation KW - Carbon dioxide KW - Tunnels KW - Biomass KW - Pasture KW - Air temperature KW - D 04625:Plants - general UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17099340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=New+Phytologist&rft.atitle=Does+greater+night-time%2C+rather+than+constant%2C+warming+alter+growth+of+managed+pasture+under+under+ambient+and+elevated+atmospheric+CO+sub%282%29%3F&rft.au=Volder%2C+A%3BEdwards%2C+E+J%3BEvans%2C+J+R%3BRobertson%2C+B+C%3BSchortemeyer%2C+M%3BGifford%2C+R+M&rft.aulast=Volder&rft.aufirst=A&rft.date=2004-05-01&rft.volume=162&rft.issue=2&rft.spage=397&rft.isbn=&rft.btitle=&rft.title=New+Phytologist&rft.issn=0028646X&rft_id=info:doi/10.1111%2Fj.1469-8137.2004.01025.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-07-01 N1 - SuppNotes - Figures, 8; tables, 2; formulas, 28; references, 44. N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Temperature effects; Daytime; Statistical analysis; Defoliation; Biomass; Tunnels; Carbon dioxide; Pasture; Air temperature; Phalaris aquatica DO - http://dx.doi.org/10.1111/j.1469-8137.2004.01025.x ER - TY - JOUR T1 - New methods of determination of average particle emission factors for two groups of vehicles on a busy road AN - 16169179; 5879164 AB - In this paper, two new methods are developed for the determination of the average emission factors of fine and ultra-fine particles for different groups of vehicles on a busy road. The values of these emission factors for heavy-duty trucks and light-duty cars are calculated, discussed, and compared with the previous results obtained mainly in laboratory conditions. JF - Atmospheric Environment AU - Gramotnev, G AU - Ristovski, Z D AU - Brown, R J AU - Madl, P AD - International Laboratory for Air Quality and Health, School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane QLD 4001, Australia., g.gramotnev@qut.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 2607 EP - 2610 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 38 IS - 16 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Air pollution KW - Pollution monitoring KW - Particulate matter emissions KW - Motor vehicles KW - Particulates KW - Exhaust emissions KW - Particulate matter from motor vehicles KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16169179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=New+methods+of+determination+of+average+particle+emission+factors+for+two+groups+of+vehicles+on+a+busy+road&rft.au=Gramotnev%2C+G%3BRistovski%2C+Z+D%3BBrown%2C+R+J%3BMadl%2C+P&rft.aulast=Gramotnev&rft.aufirst=G&rft.date=2004-05-01&rft.volume=38&rft.issue=16&rft.spage=2607&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2004.02.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2004-06-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Particulate matter emissions; Particulate matter from motor vehicles; Air pollution; Pollution monitoring; Motor vehicles; Particulates; Exhaust emissions DO - http://dx.doi.org/10.1016/j.atmosenv.2004.02.015 ER - TY - JOUR T1 - Medications as a Source of Human Exposure to Phthalates AN - 14711973; 10662615 JF - Environmental Health Perspectives AU - Hauser, Russ AU - Duty, Susan AU - Godfrey-Bailey, Linda AU - Calafat, Antonia M Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 751 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEDICAL SURVEILLANCE KW - PHTHALIC ACID ESTERS KW - DRUGS KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14711973?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Medications+as+a+Source+of+Human+Exposure+to+Phthalates&rft.au=Hauser%2C+Russ%3BDuty%2C+Susan%3BGodfrey-Bailey%2C+Linda%3BCalafat%2C+Antonia+M&rft.aulast=Hauser&rft.aufirst=Russ&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=751&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEDICAL SURVEILLANCE; PHTHALIC ACID ESTERS; DRUGS; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Urinary 8-Hydroxy-2'-Deoxyguanosine as a Biomarker of Oxidative DNA Damage in Workers Exposed to Fine Particulates AN - 14711931; 10662604 AB - In a group of boilermakers working at a power plant during an overhaul of oil-fired boilers, the association between personal exposure to fine particulate matter and oxidative DNA damage and repair, as indicated by urinary levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), was investigated. The workers were monitored over five consecutive workdays, and chemical analysis of the particulate sample was performed to determine exposure to vanadium, chromium, manganese, nickel, copper, and lead. Results showed that the median total PM sub(2.5) 8-h time-weighted average concentration was 0.44 mg/m super(3), ranging 0.290.76 mg/m super(3). Among the metals, exposures to V and Cr were highest and lowest, respectively, and each of the metal concentrations was correlated moderately to highly with total PM sub(2.5) concentrations. The mean pre-workshift 8-OHdG concentration was 13.26 mu g/g creatinine, and the mean of the cross-shift change was 1.88 mu g/g creatinine. Crude analyses revealed a significant association between PM sub(2.5) 8-h time-weighted average concentrations and urinary 8-OHdG concentrations, and the association remained statistically significant after adjusting for urinary cotinine levels, chronic bronchitis status, and age. Concentrations of V, Mn, Ni, and Pb in PM sub(2.5) showed a statistically significant association with 8-OHdG concentrations. JF - Environmental Health Perspectives AU - Kim, Jee Young AU - Mukherjee, Sutapa AU - Ngo, Long AU - Christiani, David C Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 666 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOLOGICAL INDICATORS KW - PARTICULATES KW - HEALTH SAFETY, OCCUPATIONAL KW - HEAVY METALS KW - DNA KW - OXIDANT STRESS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14711931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Urinary+8-Hydroxy-2%27-Deoxyguanosine+as+a+Biomarker+of+Oxidative+DNA+Damage+in+Workers+Exposed+to+Fine+Particulates&rft.au=Kim%2C+Jee+Young%3BMukherjee%2C+Sutapa%3BNgo%2C+Long%3BChristiani%2C+David+C&rft.aulast=Kim&rft.aufirst=Jee&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=666&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; BIOLOGICAL INDICATORS; HEAVY METALS; DNA; OXIDANT STRESS; PARTICULATES ER - TY - JOUR T1 - Health and Environmental Consequences of the World Trade Center Disaster AN - 14711002; 10662613 AB - Results are summarized from a comprehensive assessment of the impact of the chemical contaminants generated by the World Trade Center disaster in September 2001 on human health and the environment. Considered were the effects of settled dust, airborne particulate matter (PM), trace elements in PM sub(2.5), dioxin and other chlorinated compounds, asbestos, and airborne PAHs. Multi-element analyses of airborne samples collected at Ground Zero were used to generate chemical profiles that could identify specific sources of emission, and satellite images were used to characterize the spatial distribution of the material released to the atmosphere. Health risks were assessed in firefighters, cleanup and recovery workers, and community residents. The data show that exposures to chemical contaminants were not uniform following the disaster, as there were sharp gradients by time after the attack and by distance from Ground Zero. Extremely high exposures occurred in the first few hours and days, and transient increases were noted when the rubble was disturbed and fires flared. Diesel exhaust became an important contaminant during the cleanup phase, and asbestos was problematic early on. In addition, airborne dioxin levels were elevated substantially in the initial days following the disaster. In firefighters, police, and other first-responders, a positive relationship was found between intensity and duration of exposure and the severity of pulmonary effects as well as of PM levels in sputum, and an increase in the incidence of small-for-gestational-age was the major adverse health effect seen in infants borne to women who were inside the towers or within approximately ten blocks of the Work Trade Center. JF - Environmental Health Perspectives AU - Landrigan, Philip J AU - Lioy, Paul J AU - Thurston, George AU - Berkowitz, Gertrud AU - Chen, L C AU - Chillrud, Steven N AU - Gavett, Stephen H Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 731 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - ASBESTOS KW - RESPIRABLE DUST KW - PARTICULATES KW - RISK ASSESSMENT KW - HEALTH SAFETY, OCCUPATIONAL KW - REPRODUCTION, HUMAN KW - PULMONARY EFFECTS KW - DIOXINS KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14711002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Health+and+Environmental+Consequences+of+the+World+Trade+Center+Disaster&rft.au=Landrigan%2C+Philip+J%3BLioy%2C+Paul+J%3BThurston%2C+George%3BBerkowitz%2C+Gertrud%3BChen%2C+L+C%3BChillrud%2C+Steven+N%3BGavett%2C+Stephen+H&rft.aulast=Landrigan&rft.aufirst=Philip&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=731&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; HEALTH SAFETY, OCCUPATIONAL; AIR POLLUTION EFFECTS; REPRODUCTION, HUMAN; ASBESTOS; PULMONARY EFFECTS; DIOXINS; RESPIRABLE DUST; PARTICULATES; NEW YORK CITY ER - TY - JOUR T1 - Backward Estimation of Exposure to Organochlorines Using Repeated Measurements AN - 14710986; 10662611 AB - Three different backward extrapolation models were compared to estimate exposure to PCBs using data collected during three surveys that spanned 197391. The surveys focused on exposure to PCBs through consumption of sport-caught fish in Michigan. The surveys, conducted by the Michigan Department of Community Health, spanned 197374, 197982, and 198991. The three models, which are described briefly, were applied to determine the extent to which estimated PCB levels concurred with PCB concentrations measured in the past. Two backward extrapolation equations, one from 1991 through 1979 and one from 1982 through 1973, were tested for each model. Results showed that the simple decay model led to large overestimation of past exposures, while the backward exposure assessment that employed changing fish PCB levels and reduction due to breast-feeding produced an acceptable fit. The regression model based on repeated measurements, however, led to the best overall PCB estimations at each survey period. JF - Environmental Health Perspectives AU - Karmaus, Wilfried AU - Fussman, Christopher AU - Muttineni, Jyotsna AU - Zhu, Xiaobei Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 710 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - MICHIGAN KW - MATHEMATIC MODELS, BIOLOGICAL KW - BIOACCUMULATION, HUMAN KW - FOOD CONTAMINATION KW - FISHING, SPORT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710986?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Backward+Estimation+of+Exposure+to+Organochlorines+Using+Repeated+Measurements&rft.au=Karmaus%2C+Wilfried%3BFussman%2C+Christopher%3BMuttineni%2C+Jyotsna%3BZhu%2C+Xiaobei&rft.aulast=Karmaus&rft.aufirst=Wilfried&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=710&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FISHING, SPORT; POLYCHLORINATED BIPHENYLS; MICHIGAN; MATHEMATIC MODELS, BIOLOGICAL; BIOACCUMULATION, HUMAN; FOOD CONTAMINATION ER - TY - JOUR T1 - Low-Dose Agrochemicals and Lawn-Care Pesticides Induce Developmental Toxicity in Murine Preimplantation Embryos AN - 14710958; 10662610 JF - Environmental Health Perspectives AU - Greenlee, Anne R AU - Ells, Tammy M AU - Berg, Richard L Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 703 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PESTICIDE USAGE, RESIDENTIAL KW - BIOASSAY KW - CHEMICAL CONTAMINATION, MULTIPLE KW - HERBICIDE EXPOSURE KW - REPRODUCTION, ANIMAL KW - PESTICIDE EXPOSURE KW - FUNGICIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710958?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Low-Dose+Agrochemicals+and+Lawn-Care+Pesticides+Induce+Developmental+Toxicity+in+Murine+Preimplantation+Embryos&rft.au=Greenlee%2C+Anne+R%3BElls%2C+Tammy+M%3BBerg%2C+Richard+L&rft.aulast=Greenlee&rft.aufirst=Anne&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=703&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL CONTAMINATION, MULTIPLE; PESTICIDE USAGE, RESIDENTIAL; BIOASSAY; REPRODUCTION, ANIMAL; HERBICIDE EXPOSURE; PESTICIDE EXPOSURE; FUNGICIDES ER - TY - JOUR T1 - Biochemical Effect Evaluation of Perfluorooctane Sulfonic Acid-Contaminated Wood Mice (Apodemus sylvaticus) AN - 14709929; 10662607 AB - Wood mice Apodemus sylvaticus were collected at a nature reserve next to a fluorochemical production plant and at a reference location in Belgium, and liver concentrations of perfluorooctane sulfonic acid (PFOS) and some perfluorinated fatty acids were measured. Exposure effects on liver weight, relative liver weight, liver peroxisomal fatty acid beta -oxidation, and total protein content and catalase activity in the liver mitochondrial fraction were assessed, as were serum triglyceride and cholesterol levels, serum alanine aminotransferase activity, and serum potassium levels. Liver concentrations of PFOS at the exposed and reference sites ranged 0.47178.55 and 0.141.11 mu g/g, respectively, and perfluorocarboxylates were generally present at detectable concentrations in mice with the highest PFOS concentrations. Relative liver weights, mitochondrial fraction protein contents, peroxisomal beta -oxidation activity, and microsomal lipid peroxidation levels were significantly higher in mice from the exposed location. Relative liver weights and liver microsomal lipid peroxidation levels showed a significant relationship with liver PFOS concentrations. JF - Environmental Health Perspectives AU - Hoff, Philippe Tony AU - Scheirs, Jan AU - Van de Vijver, Kristin AU - Van Dongen, Walter AU - Esmans, Eddy Louis AU - Blust, Ronny AU - De Coen, Wim Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 681 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - FLUORINATED HYDROCARBONS KW - BIOACCUMULATION, ANIMAL KW - BIOCHEMISTRY KW - HEPATOTOXICITY KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biochemical+Effect+Evaluation+of+Perfluorooctane+Sulfonic+Acid-Contaminated+Wood+Mice+%28Apodemus+sylvaticus%29&rft.au=Hoff%2C+Philippe+Tony%3BScheirs%2C+Jan%3BVan+de+Vijver%2C+Kristin%3BVan+Dongen%2C+Walter%3BEsmans%2C+Eddy+Louis%3BBlust%2C+Ronny%3BDe+Coen%2C+Wim&rft.aulast=Hoff&rft.aufirst=Philippe&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=681&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOACCUMULATION, ANIMAL; FLUORINATED HYDROCARBONS; HEPATOTOXICITY; BIOCHEMISTRY; RODENTS ER - TY - JOUR T1 - Probability Estimates for the Unique Childhood Leukemia Cluster in Fallon, Nevada, and Risks near Other U.S. Military Aviation Facilities AN - 14708837; 10662618 AB - From 1999 to 2001, 11 cases of leukemia were diagnosed among children residing in Churchill County, NV, and another five cases were identified among children who were not residents at the time of diagnosis but who had lived in the county at some point prior. Large military training operations are conducted at the naval air station located in the sparsely populated county. Age-standardized incidence rate ratios for childhood leukemia in Churchill County were calculated as a whole and for the time period that only included cases diagnosed after investigation of the cluster had begun in July 2000. In addition, using all counties covered by the Surveillance, Epidemiology, and End Results (SEER) Program and the California Cancer Registry, rates of childhood leukemia in counties with military aviation bases were compared with rates in counties without military bases. Results suggested that the Churchill County cluster was not due only to chance, as it represented a twelve-fold increase above leukemia rates in SEER registries. Analysis of the larger data revealed no increase in childhood leukemia among counties with military aviation bases compared to those without bases. JF - Environmental Health Perspectives AU - Steinmaus, Craig AU - Lu, Meng AU - Todd, Randall L AU - Smith, Allan H Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 766 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - NEVADA KW - PATHOLOGY, CHILDREN KW - HUMAN T CELL LEUKEMIA VIRUS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708837?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Probability+Estimates+for+the+Unique+Childhood+Leukemia+Cluster+in+Fallon%2C+Nevada%2C+and+Risks+near+Other+U.S.+Military+Aviation+Facilities&rft.au=Steinmaus%2C+Craig%3BLu%2C+Meng%3BTodd%2C+Randall+L%3BSmith%2C+Allan+H&rft.aulast=Steinmaus&rft.aufirst=Craig&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=766&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; NEVADA; PATHOLOGY, CHILDREN; HUMAN T CELL LEUKEMIA VIRUS ER - TY - JOUR T1 - Storage of Serum in Plastic and Glass Containers May Alter the Serum Concentration of Polychlorinated Biphenyls AN - 14708804; 10662600 AB - Data obtained during a study in Michigan that examined the relationship between PCB serum concentrations in humans and adverse reproduction effects were used to examine whether plastic containers used to store serum samples altered the concentrations of PCBs, polybrominated biphenyls (PBBs), and DDE in the samples. The phlebotomists stored the samples in glass containers, but the commercial analytical laboratory transferred the specimens to plastic containers for freezing. Results showed that, while the proportions of detectable halogenated organic compounds were not different with regard to samples kept in glass or plastic containers, storage in plastic containers altered the total concentrations of PCBs, especially the higher chlorinated congeners. The concentrations of DDT and PBBs were not affected, however. JF - Environmental Health Perspectives AU - Karmaus, Wilfried AU - Riebow, John F Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 643 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PLASTICS KW - MICHIGAN KW - DDE KW - BLOOD ANALYSIS KW - POLYBROMINATED BIPHENYLS KW - GLASS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708804?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Storage+of+Serum+in+Plastic+and+Glass+Containers+May+Alter+the+Serum+Concentration+of+Polychlorinated+Biphenyls&rft.au=Karmaus%2C+Wilfried%3BRiebow%2C+John+F&rft.aulast=Karmaus&rft.aufirst=Wilfried&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=643&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYBROMINATED BIPHENYLS; POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; PLASTICS; DDE; MICHIGAN; GLASS ER - TY - JOUR T1 - Interlaboratory Comparison of Four in Vitro Assays for Assessing Androgenic and Antiandrogenic Activity of Environmental Chemicals AN - 14708661; 10662609 AB - Results from four laboratories were compared for four in vitro assays for measuring androgen receptor-mediated androgenic and antiandrogenic activity of selected environmental chemicals. The laboratories and cell types utilized are tabulated, along with the respective end point and exposure time. The test compounds included an androgen and an antiandrogen control, vinclozolin, 4-androsten-3,17-dione, 17 alpha -methyltestosterone, and tris-(4-chlorophenyl)methanol. One laboratory used cell number as the endpoint, and the other three used luciferase activity relative to the hormone-free negative control. All four test systems produced comparable quantitative results for the two androgens and two antiandrogens. However, the assay involving Chinese hamster ovary cells transiently transfected with pSVARO expression vector and MMTV-LUC reporter plasmid showed a generally greater sensitivity toward the detection of androgens. Overall, the coefficients of variation for the different EC sub(50) and IC sub(50) values were within the same range. JF - Environmental Health Perspectives AU - Korner, Wolfgang AU - Vinggaard, Anne Marie AU - Terouanne, Beatrice AU - Ma, Risheng AU - Wieloch, Carise AU - Schlumpf, Margret AU - Sultan, Charles Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 695 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - QUANTITATIVE ANALYSIS KW - HORMONAL EFFECTS KW - BIOASSAY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708661?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Interlaboratory+Comparison+of+Four+in+Vitro+Assays+for+Assessing+Androgenic+and+Antiandrogenic+Activity+of+Environmental+Chemicals&rft.au=Korner%2C+Wolfgang%3BVinggaard%2C+Anne+Marie%3BTerouanne%2C+Beatrice%3BMa%2C+Risheng%3BWieloch%2C+Carise%3BSchlumpf%2C+Margret%3BSultan%2C+Charles&rft.aulast=Korner&rft.aufirst=Wolfgang&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=695&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - QUANTITATIVE ANALYSIS; HORMONAL EFFECTS; BIOASSAY ER - TY - JOUR T1 - Retrospective Time-Trend Study of Polybrominated Diphenyl Ether and Polybrominated and Polychlorinated Biphenyl Levels in Human Serum from the United States AN - 14708618; 10662602 AB - Archived serum samples collected in the southeastern US over the period 19852002 and in Seattle, WA, over the period 19992002 were analyzed for concentrations of polybrominated diphenyl ethers (PBDEs), 2,2',4,4',5,5'-hexabromobiphenyl (PBB-153), and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153). The concentrations of all PBDEs, with the exception of BDE-85, increased significantly during the study period, while decreasing levels were found for PBB-153 and PCB-153. The decreasing trend for the latter two compounds was attributed to their being banned in the mid 1970s. JF - Environmental Health Perspectives AU - Sjodin, Andreas AU - Jones, Richard S AU - Focant, Jean-Francois AU - Lapeza, Chester AU - Wang, Richard Y AU - McGahee, Ernest E AU - Zhang, Yalin Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 654 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ETHERS KW - POLYCHLORINATED BIPHENYLS KW - BLOOD ANALYSIS KW - POLYBROMINATED BIPHENYLS KW - FLAME RETARDANTS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708618?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Retrospective+Time-Trend+Study+of+Polybrominated+Diphenyl+Ether+and+Polybrominated+and+Polychlorinated+Biphenyl+Levels+in+Human+Serum+from+the+United+States&rft.au=Sjodin%2C+Andreas%3BJones%2C+Richard+S%3BFocant%2C+Jean-Francois%3BLapeza%2C+Chester%3BWang%2C+Richard+Y%3BMcGahee%2C+Ernest+E%3BZhang%2C+Yalin&rft.aulast=Sjodin&rft.aufirst=Andreas&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=654&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ETHERS; POLYBROMINATED BIPHENYLS; POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; FLAME RETARDANTS; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Early-Life Environmental Risk Factors for Asthma: Findings from the Children's Health Study AN - 14707866; 10662617 JF - Environmental Health Perspectives AU - Salam, Muhammad Towhid AU - Li, Yu-Fen AU - Langholz, Bryan AU - Gilliland, Frank Davis Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 760 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - COCKROACHES KW - RISK ASSESSMENT KW - PATHOLOGY, CHILDREN KW - DEMOGRAPHY KW - AIR POLLUTION, INDOOR KW - ASTHMA KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707866?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Early-Life+Environmental+Risk+Factors+for+Asthma%3A+Findings+from+the+Children%27s+Health+Study&rft.au=Salam%2C+Muhammad+Towhid%3BLi%2C+Yu-Fen%3BLangholz%2C+Bryan%3BGilliland%2C+Frank+Davis&rft.aulast=Salam&rft.aufirst=Muhammad&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=760&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; PATHOLOGY, CHILDREN; DEMOGRAPHY; AIR POLLUTION, INDOOR; ASTHMA; COCKROACHES; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Magnetic-Field-Induced DNA Strand Breaks in Brain Cells of the Rat AN - 14707811; 10662608 AB - Male SpragueDawley rats were exposed to a 60-Hz magnetic field at 0.1 mT for 24 or 48 h in the laboratory, and DNA strand breaks in brain cells were assessed. In addition, treatments with the vitamin E analog, Trolox, the nitric oxide synthase inhibitor, 7-nitroindazole, and the iron chelator, deferiprone, were performed. Magnetic exposure increased single- and double-strand breaks, and increasing the exposure duration from 24 to 48 h significantly increased cumulative single- and double-strand breaks. Treatment with Trolox blocked the effects of the magnetic field on DNA strand breaks, as did the deferiprone and 7-nitroindazole treatments, which suggested that the effects of magnetic fields, in terms of DNA strand breaks, were caused by free radicals, especially by an Fe-mediated free radical process. JF - Environmental Health Perspectives AU - Lai, Henry AU - Singh, Narendra P Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 687 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - DNA KW - MUTAGENIC AGENTS KW - ELECTROMAGNETIC FIELDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707811?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Magnetic-Field-Induced+DNA+Strand+Breaks+in+Brain+Cells+of+the+Rat&rft.au=Lai%2C+Henry%3BSingh%2C+Narendra+P&rft.aulast=Lai&rft.aufirst=Henry&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=687&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; DNA; MUTAGENIC AGENTS; ELECTROMAGNETIC FIELDS ER - TY - JOUR T1 - Predictors of Personal Polycyclic Aromatic Hydrocarbon Exposures Among Pregnant Minority Women in New York City AN - 14707786; 10662616 AB - Airborne PAH personal exposures were studied in pregnant minority women in New York City, and questionnaire data were used to predict exposure. The data included race/ethnicity, socioeconomic status, medical history, lifetime residential history, and history of active and passive smoking, as well as occupational history, workplace exposures, and environmental exposures during pregnancy. Personal exposure data were collected for 344 subjects, and multiple linear regression analysis was employed to explore the roles of questionnaire variables as predictors of individual PAH concentrations as well as the sum of all compounds. Results showed that personal exposures ranged from 0.06 ng/m super(3) for dibenz[a,h]anthracene to 4.1 ng/m super(3) for pyrene, while the mean benzo[a]pyrene concentration was 0.5 ng/m super(3), and the mean total PAH concentration was 8.0 ng/m super(3). Season and a variety of indoor and outdoor sources of PAHs were found to influence the personal exposures, with the association found between total PAH and questionnaire variables driven largely by pyrene. JF - Environmental Health Perspectives AU - Tonne, Cathryn C AU - Whyatt, Robin M AU - Camann, David E AU - Perera, Frederica P AU - Kinney, Patrick L Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 754 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSIMETRY KW - POLYCYCLIC AROMATIC HYDROCARBON KW - SOCIOECONOMICS KW - DEMOGRAPHY KW - AIR POLLUTION, INDOOR KW - SEASONAL COMPARISONS KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Predictors+of+Personal+Polycyclic+Aromatic+Hydrocarbon+Exposures+Among+Pregnant+Minority+Women+in+New+York+City&rft.au=Tonne%2C+Cathryn+C%3BWhyatt%2C+Robin+M%3BCamann%2C+David+E%3BPerera%2C+Frederica+P%3BKinney%2C+Patrick+L&rft.aulast=Tonne&rft.aufirst=Cathryn&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=754&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSIMETRY; SOCIOECONOMICS; DEMOGRAPHY; AIR POLLUTION, INDOOR; SEASONAL COMPARISONS; NEW YORK CITY; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Phytoestrogen Signaling and Symbiotic Gene Activation Are Disrupted by Endocrine-Disrupting Chemicals AN - 14707752; 10662605 AB - Phytoestrogens act as specific attractants for symbiotic Rhizobium soil bacteria. Host specificity between plants and Rhizobium is regulated by the unique profile of phytoestrogens produced by the host plant, which are recognized by species-specific nodulation D (NodD) proteins within Rhizobium soil bacteria, with this NodDligand specificity regulating transcription of key nod genes. Using the wild-type Rhizobium strain, Sinorhizobium meliloti 1021 pRmM57, the effects of natural and synthetic chemicals on phytochemical signaling to NodD receptors were examined. The chemicals included PCBs, insecticides, 17 beta -estradiol, diethylstilbestrol, and phytochemicals. Results showed that environmentally relevant concentrations of 45 of the 62 endocrine-disrupting chemicals and organochlorine pesticides statistically significantly inhibited luteolin-NodD receptor signaling and symbiotic nod gene activation. Many of the compounds exhibited doseresponsive, concentration-dependent inhibition of luteolin-NodD-induced nod gene expression. JF - Environmental Health Perspectives AU - Fox, Jennifer E AU - Starcevic, Marta AU - Jones, Phillip E AU - Burow, Matthew E AU - McLachlan, John A Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 672 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BACTERIA KW - POLYCHLORINATED BIPHENYLS KW - HORMONAL EFFECTS KW - NITROGEN FIXATION KW - SYMBIOSIS KW - ORGANOCHLORINE PESTICIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707752?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Phytoestrogen+Signaling+and+Symbiotic+Gene+Activation+Are+Disrupted+by+Endocrine-Disrupting+Chemicals&rft.au=Fox%2C+Jennifer+E%3BStarcevic%2C+Marta%3BJones%2C+Phillip+E%3BBurow%2C+Matthew+E%3BMcLachlan%2C+John+A&rft.aulast=Fox&rft.aufirst=Jennifer&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=672&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BACTERIA; POLYCHLORINATED BIPHENYLS; HORMONAL EFFECTS; SYMBIOSIS; NITROGEN FIXATION; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Human Consumption of Methyleugenol and Its Elimination from Serum AN - 14707749; 10662606 AB - Methyleugenol occurs naturally in a number of exotic herbs and spices and is used commonly as a flavoring agent in foods. The levels of methyleugenol in human blood were measured at specific times before and after eating gingersnap cookies, known to contain the compound. The 20 study subjects fasted from midnight until the study commenced, and they were fed gingersnaps that contained approximately 3.3 mu g methyleugenol/g. The meal consisted of 12 cookies containing approximately 216 mu g methyleugenol. Blood was drawn for analysis prior to the meal and at 15, 30, 60, and 120 min after the meal. The median fasting level of methyleugenol in serum was 13 pg/g, and the median serum level at 15 min after the meal peaked at 54 pg/g, declining to 40 pg/g at 30 min, to 29 pg/g at 60 min, and to 20 pg/g at 120 min. JF - Environmental Health Perspectives AU - Schecter, Arnold AU - Lucier, George W AU - Cunningham, Michael L AU - Abdo, Kamal M AU - Blumenthal, Greg AU - Silver, Andrew G AU - Melnick, Ron Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 678 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - DISSIPATION RATES KW - CARCINOGENIC AGENTS KW - FOOD ADDITIVES KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707749?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Human+Consumption+of+Methyleugenol+and+Its+Elimination+from+Serum&rft.au=Schecter%2C+Arnold%3BLucier%2C+George+W%3BCunningham%2C+Michael+L%3BAbdo%2C+Kamal+M%3BBlumenthal%2C+Greg%3BSilver%2C+Andrew+G%3BMelnick%2C+Ron&rft.aulast=Schecter&rft.aufirst=Arnold&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=678&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; DISSIPATION RATES; CARCINOGENIC AGENTS; FOOD ADDITIVES; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Association Between Hemochromatosis Genotype and Lead Exposure Among Elderly Men: the Normative Aging Study AN - 14707116; 10662614 AB - Using a subsample of the Normative Aging Study established by the Veterans Administration in 1963 to assess lead biomarkers and chronic disease, elderly men were genotyped in terms of the C282Y and/or H63D hemochromatosis gene associated with body Pb burden. Bone Pb measurements were taken at the mid-tibial shaft and the patella, and blood Pb levels were measured. Of the 765 subjects, 730 were genotyped for H63D and C282Y. The overall trend in the bone and blood Pb levels was that carriers of the hemochromatosis gene variants had lower bone and blood Pb levels. Subjects with either one or two copies of either allele had lower bone or blood Pb levels, on average, than did wild-type subjects. The findings suggested that subjects with the hemochromatosis gene variants may have higher iron stores, on average, and lower Pb absorption because of the decreased risk of Fe deficiency. JF - Environmental Health Perspectives AU - Wright, Robert O AU - Silverman, Edwin K AU - Schwartz, Joel AU - Tsaih, Shring-Wern AU - Senter, Jody AU - Sparrow, David AU - Weiss, Scott T Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 746 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - BIOACCUMULATION, HUMAN KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707116?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+Between+Hemochromatosis+Genotype+and+Lead+Exposure+Among+Elderly+Men%3A+the+Normative+Aging+Study&rft.au=Wright%2C+Robert+O%3BSilverman%2C+Edwin+K%3BSchwartz%2C+Joel%3BTsaih%2C+Shring-Wern%3BSenter%2C+Jody%3BSparrow%2C+David%3BWeiss%2C+Scott+T&rft.aulast=Wright&rft.aufirst=Robert&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=746&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD LEAD LEVEL; GENETICS, HUMAN; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Maternal Stress Modulates the Effects of Developmental Lead Exposure AN - 14707078; 10662612 AB - To examine the possible interaction between maternal stress and lead exposure on behavioral and neurochemical development in offspring, male and female Long-Evans rats were used involving four experimental groups of dams: no maternal stress; no Pb exposure; no maternal stress, Pb exposure; and maternal stress plus Pb exposure. Maternal stress involved constraint on gestation days 16 and 17, and the Pb exposure concentration was 150 ppm in drinking water. Long-term behavioral effects in offspring were assessed using a fixed-interval schedule of food reinforcement, which was preceded by locomotor activity testing in both sexes when male offspring were 60 d old and females were 80100 d old. Results showed that Pb exposure and stress interacted. Not only did the consequences of preweaning Pb alone, maternal stress alone, and their combination differ markedly by sex, but each had permanent consequences for offspring that manifested variously as changes in neurochemical measures, corticosteroid systems, and/or behavior. The effects of Pb exposure were more prominent than those of stress in male offspring, whereas in female offspring, the impact of prenatal stress predominated in the behavioral effects. JF - Environmental Health Perspectives AU - Cory-Slechta, Deborah A AU - Virgolini, Miriam B AU - Thiruchelvam, Mona AU - Weston, Doug D AU - Bauter, Mark R Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 717 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - PSYCHOLOGICAL EFFECTS KW - NEUROTOXICITY KW - BEHAVIOR KW - REPRODUCTION, ANIMAL KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707078?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Maternal+Stress+Modulates+the+Effects+of+Developmental+Lead+Exposure&rft.au=Cory-Slechta%2C+Deborah+A%3BVirgolini%2C+Miriam+B%3BThiruchelvam%2C+Mona%3BWeston%2C+Doug+D%3BBauter%2C+Mark+R&rft.aulast=Cory-Slechta&rft.aufirst=Deborah&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=717&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; NEUROTOXICITY; PSYCHOLOGICAL EFFECTS; BEHAVIOR; LEAD; REPRODUCTION, ANIMAL ER - TY - JOUR T1 - Chemical Communication Threatened by Endocrine-Disrupting Chemicals AN - 14707025; 10662601 AB - The evolution of communication via hormone signaling may be one of the oldest and most crucial links shared between all organisms. For chemical communication to occur, a receptor must have affinity for specific chemical ligands or signals, and the recognition must initiate a response. A number of natural and synthetic chemicals exist in the environment, however, which mimic hormones and disrupt endocrine signaling in vertebrates through interaction with various nuclear receptors and signal transducer proteins. The mechanism of action is defined by vertebrate estrogen receptors (ERs), which bind phytoestrogen ligands, endogenous ligands, and endocrine-disrupting chemicals with specific affinity. Nodulation D protein (NodD) receptors in Rhizobium soil bacteria recognize phytoestrogens as recruitment signals to initiate nitrogen-fixing symbiosis. Although they share no common evolutionary ancestor, NodD and ER recognize and respond to a similar profile of chemical signals found in the environment. It is argued here that both of the signaling systems are vulnerable to disruption by endocrine-disrupting chemicals present in their shared environment. This disruption is described, citing data from a number of studies, and the implications of the disruption are discussed. JF - Environmental Health Perspectives AU - Fox, Jennifer E Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 648 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HORMONAL EFFECTS KW - CHEMICAL CONTAMINATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707025?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Chemical+Communication+Threatened+by+Endocrine-Disrupting+Chemicals&rft.au=Fox%2C+Jennifer+E&rft.aulast=Fox&rft.aufirst=Jennifer&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=648&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HORMONAL EFFECTS; CHEMICAL CONTAMINATION ER - TY - JOUR T1 - Synergistic Interaction in Simultaneous Exposure to Streptomyces californicus and Stachybotrys chartarum AN - 14704729; 10662603 AB - Mouse RAW264.7 macrophages were exposed simultaneously to the gram-positive bacterium, Streptomyces californicus, and to Aspergillus versicolor, Penicillium spinulosum, Stachybotrys chartarum, Bacillus cereus, Mycobacterium terrae, or Pseudomonas fluorescens, and their interaction was examined. In addition, known mycotoxins were tested for their inflammatory and cytotoxic potency alone and together with S. californicus. Results showed that only S. chartarum was able to potentiate the inflammatory effect of S. californicus, and among the metabolites produced typically by S. chartarum, there was at least one compound, trichodermin, that produced a similar synergistic effect along with a closely related compound, 7- alpha -hydroxytrichodermol. Exposure to S. californicus induced the nuclear binding activity of nuclear factor-B. While spores of S. chartarum alone were not able to evoke any inflammatory responses in macrophages, they triggered a significant, dose-dependent cytokine response in cells when exposed in conjunction with a low dose of S. californicus. JF - Environmental Health Perspectives AU - Huttunen, Kati AU - Pelkonen, Jukka AU - Nielsen, Kristian Fogg AU - Nuutinen, Ulla AU - Jussila, Juha AU - Hirvonen, Maija-Riitta Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 659 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BACTERIA KW - CYTOTOXICITY KW - SYNERGISTIC EFFECTS KW - IMMUNE RESPONSE KW - FUNGI KW - MYCOTOXINS KW - AIR POLLUTION, INDOOR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704729?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Synergistic+Interaction+in+Simultaneous+Exposure+to+Streptomyces+californicus+and+Stachybotrys+chartarum&rft.au=Huttunen%2C+Kati%3BPelkonen%2C+Jukka%3BNielsen%2C+Kristian+Fogg%3BNuutinen%2C+Ulla%3BJussila%2C+Juha%3BHirvonen%2C+Maija-Riitta&rft.aulast=Huttunen&rft.aufirst=Kati&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=659&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FUNGI; BACTERIA; CYTOTOXICITY; AIR POLLUTION, INDOOR; MYCOTOXINS; SYNERGISTIC EFFECTS; IMMUNE RESPONSE ER - TY - JOUR T1 - Inhibition of Ape1 Nuclease Activity by Lead, Iron, and Cadmium AN - 14699284; 10662929 AB - Reduced DNA repair capacity can lead to genetic instability and human disease, and studies have suggested that environmental metals are co-mutagenic, potentiating the carcinogenic effects of DNA-damaging agents by inhibiting DNA repair processes. Apurinic/apyrimidinic (AP) sites are frequent lesions in DNA, generated by spontaneous, damage-induced, or enzyme-catalyzed hydrolysis of the N-glycosylic bond. If unrepaired, these noncoding lesions present both cytotoxic and mutagenic challenges to the cell, with AP endonuclease 1 (Ape1) the major mammalian abasic endonuclease, accounting for greater than 95% of the total cellular AP site incision activity. Results are presented from a study in which the effects of divalent lead, iron, and cadmium on Ape1 nuclease activity were examined using a 26-mer oligonucleotide duplex containing a single, centrally located abasic site analog. Results show that all three metals specifically inhibited AP endonuclease activity in whole-cell extracts but did not dramatically affect other steps of repair. JF - Environmental Health Perspectives AU - McNeill, Daniel R AU - Narayana, Avinash AU - Wong, Heng-Kuan AU - Wilson, David M Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 799 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CADMIUM KW - CARCINOGENIC MECHANISMS KW - DNA KW - LEAD KW - MUTAGENIC AGENTS KW - IRON KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699284?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Inhibition+of+Ape1+Nuclease+Activity+by+Lead%2C+Iron%2C+and+Cadmium&rft.au=McNeill%2C+Daniel+R%3BNarayana%2C+Avinash%3BWong%2C+Heng-Kuan%3BWilson%2C+David+M&rft.aulast=McNeill&rft.aufirst=Daniel&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=799&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CARCINOGENIC MECHANISMS; DNA; LEAD; CADMIUM; MUTAGENIC AGENTS; IRON ER - TY - JOUR T1 - Metal Particulate Matter Components Affect Gene Expression and Beat Frequency of Neonatal Rat Ventricular Myocytes AN - 14695291; 10662928 AB - Ventricular myocytes were isolated from 1-d-old SpragueDawley rats, and the cytotoxicity produced by exposure to various concentrations of zinc and vanadium was assessed. Measurements of spontaneous beat rate were also conducted on the cells, as were reverse transcription and quantitative real-time polymerase chain reaction. Results revealed that both Zn and V modulated the function of cardiac myocytes by slowing their spontaneous beat rate, analogous to slowing of the heart rate demonstrated previously in rats instilled with residual oil flyash containing high levels of the metals. The decrease induced by Zn, however, was significantly more pronounced than that induced by V, occurring at lower concentrations and shorter exposure times. Exposure to Zn for 24 h resulted in a greater increase in the accumulation of mRNAs coding for interleukin-6 and heat shock protein 70 than that observed after exposure for 6 h, and marked changes in gene expression of several ion channel and gap junction proteins were also observed. JF - Environmental Health Perspectives AU - Graff, Donald W AU - Cascio, Wayne E AU - Brackhan, Joseph A AU - Devlin, Robert B Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 792 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CYTOTOXICITY KW - CARDIOVASCULAR EFFECTS KW - RATS KW - PARTICULATES KW - ZINC KW - DOSE RESPONSE PROFILES KW - VANADIUM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695291?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Metal+Particulate+Matter+Components+Affect+Gene+Expression+and+Beat+Frequency+of+Neonatal+Rat+Ventricular+Myocytes&rft.au=Graff%2C+Donald+W%3BCascio%2C+Wayne+E%3BBrackhan%2C+Joseph+A%3BDevlin%2C+Robert+B&rft.aulast=Graff&rft.aufirst=Donald&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=792&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 11 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ZINC; AIR POLLUTION EFFECTS; DOSE RESPONSE PROFILES; CYTOTOXICITY; CARDIOVASCULAR EFFECTS; VANADIUM; RATS; PARTICULATES ER - TY - JOUR T1 - Using a Customized DNA Microarray for Expression Profiling of the Estrogen-Responsive Genes to Evaluate Estrogen Activity Among Natural Estrogens and Industrial Chemicals AN - 14694608; 10662926 JF - Environmental Health Perspectives AU - Terasaka, Shunichi AU - Aita, Yukie AU - Inoue, Akio AU - Hayashi, Shinichi AU - Nishigaki, Michiko AU - Aoyagi, Kazuhiko AU - Sasaki, Hiroki Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 773 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - DNA KW - HORMONAL EFFECTS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694608?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+a+Customized+DNA+Microarray+for+Expression+Profiling+of+the+Estrogen-Responsive+Genes+to+Evaluate+Estrogen+Activity+Among+Natural+Estrogens+and+Industrial+Chemicals&rft.au=Terasaka%2C+Shunichi%3BAita%2C+Yukie%3BInoue%2C+Akio%3BHayashi%2C+Shinichi%3BNishigaki%2C+Michiko%3BAoyagi%2C+Kazuhiko%3BSasaki%2C+Hiroki&rft.aulast=Terasaka&rft.aufirst=Shunichi&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=773&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; HORMONAL EFFECTS; DNA; GENETICS, HUMAN ER - TY - JOUR T1 - Toxicogenomics of Subchronic Hexachlorobenzene Exposure in Brown Norway Rats AN - 14694103; 10662927 AB - DNA microarray analysis was used to assess changes associated with hexachlorobenzene exposure in Brown Norway rats at the gene expression level. The rats were exposed to 0, 150, or 450 mg hexachlorobenzene/kg diet, and gene expression levels were assessed in spleen, mesenteric lymph nodes, thymus, blood, liver, and kidney. Previously observed effects of hexachlorobenzene exposure were noted, including stimulatory effects on the immune system and induction of enzymes involved in drug metabolism, porphyria, and the reproductive system, but several novel effects were also discerned, including upregulation of genes encoding proinflammatory cytokines, antioxidants, acute phase proteins, complement, mast cell markers, chemokines, and cell adhesion molecules. The gene expression profiles provided evidence for the importance of macrophages and granulocytes and mediators released by these cells in the adverse inflammatory response against hexachlorobenzene. JF - Environmental Health Perspectives AU - Ezendam, Janine AU - Staedtler, Frank AU - Pennings, Jeroen AU - Vandebriel, Rob J AU - Pieters, Raymond AU - Harleman, Johannes H AU - Vos, Joseph G Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 782 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEXACHLOROBENZENE KW - RATS KW - IMMUNOTOXICITY KW - GENETICS, ANIMAL KW - DOSE RESPONSE PROFILES KW - DNA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694103?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Toxicogenomics+of+Subchronic+Hexachlorobenzene+Exposure+in+Brown+Norway+Rats&rft.au=Ezendam%2C+Janine%3BStaedtler%2C+Frank%3BPennings%2C+Jeroen%3BVandebriel%2C+Rob+J%3BPieters%2C+Raymond%3BHarleman%2C+Johannes+H%3BVos%2C+Joseph+G&rft.aulast=Ezendam&rft.aufirst=Janine&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=782&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - IMMUNOTOXICITY; GENETICS, ANIMAL; DOSE RESPONSE PROFILES; DNA; HEXACHLOROBENZENE; RATS ER - TY - JOUR T1 - Arsenic removal from aqueous solution via ferrihydrite crystallization control. AN - 71880332; 15116842 AB - Removal of arsenate anion from aqueous solution by coprecipitation with ferrihydrite has been studied under conditions in which the Fe/As ratio is maintained at a constant level, while the degree of supersaturation with respect to the iron oxide precipitate is varied. An Fe/As ratio of 12 was chosen, and supersaturation was controlled by varying the iron concentration or the pH. The relationship between supersaturation and arsenic removal was found to follow an exponential curve, with greater arsenic removal occurring at higher supersaturation ratios for each of the pH values tested. Higher supersaturation ratios were required to achieve a given level of arsenic removal at pH 7 than would be required to achieve the same level of removal at pH 3.5. The results provide important guidelines for selection of appropriate concentrations of iron(III) required for arsenic removal under various circumstances. Powder XRD analysis of the arsenate-ferrihydrite precipitates showed an increasing degree of structural order with decreasing levels of supersaturation. TEM images of the precipitates revealed that aggregates with a morphology similar to that of schwertmannite are formed in some samples at low supersaturation levels. The results described in this paper indicate that the overall efficiency of arsenic removal involves a combination of both supersaturation and pH effects, with pH controlling the affinity of arsenate for the ferrihydrite surface, and supersaturation controlling the surface area and physical properties of the ferrihydrite product. JF - Environmental science & technology AU - Richmond, William R AU - Loan, Mitch AU - Morton, Jonathon AU - Parkinson, Gordon M AD - Nanochemistry Research Institute and A. J. Parker CRC for Hydrometallurgy, Curtin University of Technology, GPO Box U 1987, Perth, 6845, Australia. bill@power.curtin.edu.au Y1 - 2004/04/15/ PY - 2004 DA - 2004 Apr 15 SP - 2368 EP - 2372 VL - 38 IS - 8 SN - 0013-936X, 0013-936X KW - Ferric Compounds KW - 0 KW - Water Pollutants KW - ferric oxyhydroxide KW - 87PZU03K0K KW - Ferritins KW - 9007-73-2 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Crystallization KW - Hydrogen-Ion Concentration KW - Chemical Precipitation KW - Ferritins -- chemistry KW - Water Purification -- methods KW - Water Pollutants -- isolation & purification KW - Arsenic -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71880332?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Arsenic+removal+from+aqueous+solution+via+ferrihydrite+crystallization+control.&rft.au=Richmond%2C+William+R%3BLoan%2C+Mitch%3BMorton%2C+Jonathon%3BParkinson%2C+Gordon+M&rft.aulast=Richmond&rft.aufirst=William&rft.date=2004-04-15&rft.volume=38&rft.issue=8&rft.spage=2368&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-07-13 N1 - Date created - 2004-04-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The effect of abrupt osmotic shifts on the lag phase duration of physiologically distinct populations of Salmonella typhimurium. AN - 71865625; 15109788 AB - Relative lag time (RLT), i.e. lag time divided by generation time, was used to characterise the lag phase response of exponential and stationary phase Salmonella typhimurium subjected to NaCl-mediated hyperosmotic shifts. Abrupt hyperosmotic shifts induced lag phases. The RLT, however, varied with the physiological history of the inoculum and the magnitude of the shift. Turbidimetric data showed that exponential phase cells had larger RLTs (up to approximately 8 units) than stationary phase cells (up to 2-4 units). Inocula containing exponential and stationary phase cells mixed in known proportions gave intermediate results. For viable count data, there was little difference in RLT between exponential and stationary phase cells. The RLT response determined turbidimetrically was reproducible for exponential phase cells, but less so for stationary phase cells. It is suggested that there may be a lower limit for resolution of RLT, in the range 0-2 units, and that this may account for the lack of reproducibility in RLTs of stationary phase cells. It is hypothesised that stationary phase cells have enhanced resistance to osmotic stress and are able to exploit new growth environments at low a(w) more rapidly than exponential phase cells, resulting in shorter lag phases. However, the data indicate that turbidimetry may not accurately describe the lag phase response of exponential phase cells subjected to large osmotic shifts. Viable count data is required to investigate this hypothesis further. JF - International journal of food microbiology AU - Mellefont, L A AU - McMeekin, T A AU - Ross, T AD - Centre for Food Safety and Quality, School of Agricultural Science, University of Tasmania, GPO Box 252-54, Hobart 7001, Tasmania, Australia. Lyndal.Mellefont@utas.edu.au Y1 - 2004/04/15/ PY - 2004 DA - 2004 Apr 15 SP - 111 EP - 120 VL - 92 IS - 2 SN - 0168-1605, 0168-1605 KW - Sodium Chloride KW - 451W47IQ8X KW - Index Medicus KW - Food Microbiology KW - Nephelometry and Turbidimetry KW - Colony Count, Microbial KW - Models, Biological KW - Osmosis KW - Salmonella typhimurium -- physiology KW - Salmonella typhimurium -- growth & development KW - Sodium Chloride -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71865625?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+food+microbiology&rft.atitle=The+effect+of+abrupt+osmotic+shifts+on+the+lag+phase+duration+of+physiologically+distinct+populations+of+Salmonella+typhimurium.&rft.au=Mellefont%2C+L+A%3BMcMeekin%2C+T+A%3BRoss%2C+T&rft.aulast=Mellefont&rft.aufirst=L&rft.date=2004-04-15&rft.volume=92&rft.issue=2&rft.spage=111&rft.isbn=&rft.btitle=&rft.title=International+journal+of+food+microbiology&rft.issn=01681605&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-19 N1 - Date created - 2004-04-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Photosynthetic pigments in 37 species (65 strains) of Haptophyta: implications for oceanography and chemotaxonomy AN - 17997697; 5930217 AB - The pigment compositions of 37 species (65 strains) of cultured haptophytes were analysed using improved HPLC methods. We distinguished 8 pigment types based on the distribution of 9 chlorophyll c (chl c) pigments and 5 fucoxanthin derivatives. All types contained chl c sub(2) and Mg-2,4-divinyl phaeoporphyrin a sub(5) monomethyl ester (MgDVP), fucoxanthin, diadinoxanthin and beta , beta -carotene. Pigment types were based on the following additional pigments: Type 1: chl c sub(1); Type 2: chl c sub(1) and chl c sub(2)-Pavlova gyrans-type; Type 3: chl c sub(1) and chl c sub(2)-monogalactosyl diacylglyceride ester (chl c sub(2)-MGDG [18:4/14:0]); Type 4: chl c sub(1), chl c sub(3) and non-polar chl c sub(1)-like; Type 5: chl c sub(1), chl c sub(3), chl c sub(2)-MGDG [18:4/14:0] and 4-keto-fucoxanthin; Type 6: chl c sub(3), monovinyl chl c sub(3) (MV-chl c sub(3)), chl c sub(2)-MGDG [18:4/14:0], 19'-hexanoyloxyfucoxanthin and its 4-keto derivative, and traces of 19'-butanoyloxyfucoxanthin; Type 7: similar to Type 6, minus MV-chl c sub(3) but with chl c sub(2)-MGDG [14:0/14:0] added; Type 8: similar to Type 6, minus MV-chl c sub(3) but with significant 19'-butanoyloxyfucoxanthin. Taxonomic associations ranged from single genera to multiple families - Type 1: Pavlovaceae, Isochrysidaceae and Pleurochrysidaceae; Type 2: Pavlovaceae; Type 3: Isochrysidaceae; Type 4: Prymnesium spp.; Type 5: Ochrosphaera spp.; Type 6: Noeelaerhabdaceae, notably Emiliania spp.; Type 7: Chrysochromulina spp.; Type 8: Phaeocystaceae, Prymnesiaceae and Isochrysidaceae. These pigment types showed a strong correlation with available phylogenetic trees, supporting a genetic basis for the pigment associations. The additional marker pigments offer oceanographers greater power for detecting haptophytes in mixed populations, while also distinguishing a greater proportion of them from diatoms. JF - Marine Ecology Progress Series AU - Zapata, M AU - Jeffrey, S W AU - Wright, S W AU - Rodriguez, F AU - Garrido, J L AU - Clementson, L AD - CSIRO Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, shirley.jeffrey@csiro.au Y1 - 2004/04/14/ PY - 2004 DA - 2004 Apr 14 SP - 83 EP - 102 VL - 270 SN - 0171-8630, 0171-8630 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts KW - High-performance liquid chromatography KW - Photosynthetic pigments KW - Taxonomy KW - Oceanography KW - Haptophyta KW - Algae KW - D 04627:Algae/lichens KW - K 03044:Algae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17997697?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Ecology+Progress+Series&rft.atitle=Photosynthetic+pigments+in+37+species+%2865+strains%29+of+Haptophyta%3A+implications+for+oceanography+and+chemotaxonomy&rft.au=Zapata%2C+M%3BJeffrey%2C+S+W%3BWright%2C+S+W%3BRodriguez%2C+F%3BGarrido%2C+J+L%3BClementson%2C+L&rft.aulast=Zapata&rft.aufirst=M&rft.date=2004-04-14&rft.volume=270&rft.issue=&rft.spage=83&rft.isbn=&rft.btitle=&rft.title=Marine+Ecology+Progress+Series&rft.issn=01718630&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Haptophyta; Photosynthetic pigments; Oceanography; High-performance liquid chromatography; Taxonomy; Algae ER - TY - JOUR T1 - Population genetic structure of the perlemoen Haliotis midae in South Africa: evidence of range expansion and founder events AN - 17981157; 5930223 AB - Genetic diversity in Haliotis midae, a highly valued and heavily exploited marine gastropod, was assessed using 3 marker types across samples from the species' range in South Africa. Variation was compared at 7 allozyme loci, 2 regions of mitochondrial DNA and 3 microsatellite loci. We conclude that populations of H. midae on either side of Cape Agulhas represent 2 independent reproductive stocks. The area of transition between the stocks coincides with oceanographic features of the region. Evidence from all 3 types of genetic marker indicates an isolated introduction event to the east of Cape Agulhas, and subsequent range expansion in an easterly direction. The disparity between allozyme data and the other 2 forms is seen as further evidence for the presence of balancing selection at allozyme loci. JF - Marine Ecology Progress Series AU - Evans, B S AU - Sweijd, NA AU - Bowie, RCK AU - Cook, P A AU - Elliott, NG AD - School of Zoology, University of Tasmania, GPO Box 252-05, Hobart, Tasmania 7001, Australia, brad.evans@jcu.edu.au Y1 - 2004/04/14/ PY - 2004 DA - 2004 Apr 14 SP - 163 EP - 172 VL - 270 SN - 0171-8630, 0171-8630 KW - Ecology Abstracts KW - Population genetics KW - Haliotis midae KW - South Africa KW - Genetic structure KW - D 04658:Molluscs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17981157?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Ecology+Progress+Series&rft.atitle=Population+genetic+structure+of+the+perlemoen+Haliotis+midae+in+South+Africa%3A+evidence+of+range+expansion+and+founder+events&rft.au=Evans%2C+B+S%3BSweijd%2C+NA%3BBowie%2C+RCK%3BCook%2C+P+A%3BElliott%2C+NG&rft.aulast=Evans&rft.aufirst=B&rft.date=2004-04-14&rft.volume=270&rft.issue=&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Marine+Ecology+Progress+Series&rft.issn=01718630&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Haliotis midae; South Africa; Population genetics; Genetic structure ER - TY - JOUR T1 - A novel secreted protein toxin from the insect pathogenic bacterium Xenorhabdus nematophila. AN - 71806897; 14707137 AB - The bacterium Xenorhabdus nematophila is an insect pathogen that produces several proteins that enable it to kill insects. Screening of a cosmid library constructed from X. nematophila strain A24 identified a gene that encoded a novel protein that was toxic to insects. The 42-kDa protein encoded by the toxin gene was expressed and purified from a recombinant system, and was shown to kill the larvae of insects such as Galleria mellonella and Helicoverpa armigera when injected at doses of around 30-40 ng/g larvae. Sequencing and bioinformatic analysis suggested that the toxin was a novel protein, and that it was likely to be part of a genomic island involved in pathogenicity. When the native bacteria were grown under laboratory conditions, a soluble form of the 42-kDa toxin was secreted only by bacteria in the phase II state. Preliminary histological analysis of larvae injected with recombinant protein suggested that the toxin primarily acted on the midgut of the insect. Finally, some of the common strategies used by the bacterial pathogens of insects, animals, and plants are discussed. JF - The Journal of biological chemistry AU - Brown, Susan E AU - Cao, Anh T AU - Hines, Eric R AU - Akhurst, Raymond J AU - East, Peter D AD - CSIRO Entomology, GPO Box 1700, Acton, Australian Capital Territory 2601, Australia. sue.brown@csiro.au Y1 - 2004/04/09/ PY - 2004 DA - 2004 Apr 09 SP - 14595 EP - 14601 VL - 279 IS - 15 SN - 0021-9258, 0021-9258 KW - Recombinant Proteins KW - 0 KW - Toxins, Biological KW - Index Medicus KW - Software KW - Animals KW - Escherichia coli -- metabolism KW - Dose-Response Relationship, Drug KW - Electrophoresis, Polyacrylamide Gel KW - Biological Assay KW - Amino Acid Sequence KW - Cosmids KW - Photorhabdus -- metabolism KW - Base Sequence KW - Blotting, Western KW - Larva -- microbiology KW - Molecular Sequence Data KW - Recombinant Proteins -- chemistry KW - Time Factors KW - Gene Library KW - Xenorhabdus -- metabolism KW - Toxins, Biological -- chemistry KW - Insects -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71806897?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+biological+chemistry&rft.atitle=A+novel+secreted+protein+toxin+from+the+insect+pathogenic+bacterium+Xenorhabdus+nematophila.&rft.au=Brown%2C+Susan+E%3BCao%2C+Anh+T%3BHines%2C+Eric+R%3BAkhurst%2C+Raymond+J%3BEast%2C+Peter+D&rft.aulast=Brown&rft.aufirst=Susan&rft.date=2004-04-09&rft.volume=279&rft.issue=15&rft.spage=14595&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+biological+chemistry&rft.issn=00219258&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-01 N1 - Date created - 2004-04-06 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: J Biol Chem. 2011 Oct 14;286(41):36161 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Stress, colon cancer and workers' compensation. AN - 71798512; 15059056 JF - The Medical journal of Australia AU - Nisselle, Paul AD - Medical Panels, GPO Box 2709X, Melbourne, Victoria 3001, Australia. nisselp@ozemail.com.au Y1 - 2004/04/05/ PY - 2004 DA - 2004 Apr 05 SP - 341 EP - 342 VL - 180 IS - 7 SN - 0025-729X, 0025-729X KW - Index Medicus KW - Probability KW - Prisons KW - Workload -- psychology KW - Risk Factors KW - Humans KW - Middle Aged KW - South Australia KW - Male KW - Expert Testimony -- legislation & jurisprudence KW - Workers' Compensation -- legislation & jurisprudence KW - Occupational Diseases -- psychology KW - Colorectal Neoplasms -- psychology KW - Stress, Psychological -- complications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71798512?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Medical+journal+of+Australia&rft.atitle=Stress%2C+colon+cancer+and+workers%27+compensation.&rft.au=Nisselle%2C+Paul&rft.aulast=Nisselle&rft.aufirst=Paul&rft.date=2004-04-05&rft.volume=180&rft.issue=7&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=The+Medical+journal+of+Australia&rft.issn=0025729X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-17 N1 - Date created - 2004-04-02 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment On: Med J Aust. 2004 Apr 5;180(7):339-40 [15059055] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hydrolysis of organophosphorus insecticides by in vitro modified carboxylesterase E3 from Lucilia cuprina. AN - 71769558; 15041019 AB - Resistance of the blowfly, Lucilia cuprina, to organophosphorus (OP) insecticides is due to mutations in LcalphaE7, the gene encoding carboxylesterase E3, that enhance the enzyme's ability to hydrolyse insecticides. Two mutations occur naturally, G137D in the oxyanion hole of the esterase, and W251L in the acyl binding pocket. Previous in vitro mutagenesis and expression of these modifications to the cloned gene have confirmed their functional significance. G137D enhances hydrolysis of diethyl and dimethyl phosphates by 55- and 33-fold, respectively. W251L increases dimethyl phosphate hydrolysis similarly, but only 10-fold for the diethyl homolog; unlike G137D however, it also retains ability to hydrolyse carboxylesters in the leaving group of malathion (malathion carboxylesterase, MCE), conferring strong resistance to this compound. In the present work, we substituted these and nearby amino acids by others expected to affect the efficiency of the enzyme. Changing G137 to glutamate or histidine was less effective than aspartate in improving OP hydrolase activity and like G137D, it diminished MCE activity, primarily through increases in Km. Various substitutions of W251 to other smaller residues had a broadly similar effect to W251L on OP hydrolase and MCE activities, but at least two were quantitatively better in kinetic parameters relating to malathion resistance. One, W251G, which occurs naturally in a malathion resistant hymenopterous parasitoid, improved MCE activity more than 20-fold. Mutations at other sites near the bottom of the catalytic cleft generally diminished OP hydrolase and MCE activities but one, F309L, also yielded some improvements in OP hydrolase activities. The results are discussed in relation to likely steric effects on enzyme-substrate interactions and future evolution of this gene. JF - Insect biochemistry and molecular biology AU - Heidari, R AU - Devonshire, A L AU - Campbell, B E AU - Bell, K L AU - Dorrian, S J AU - Oakeshott, J G AU - Russell, R J AD - CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia. Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 353 EP - 363 VL - 34 IS - 4 SN - 0965-1748, 0965-1748 KW - Anions KW - 0 KW - Insecticides KW - Isoenzymes KW - Naphthalenes KW - Carboxylesterase KW - EC 3.1.1.1 KW - Acetylcholinesterase KW - EC 3.1.1.7 KW - Malathion KW - U5N7SU872W KW - Index Medicus KW - Isoenzymes -- chemistry KW - Animals KW - Naphthalenes -- chemistry KW - Torpedo KW - Humans KW - Anions -- chemistry KW - Amino Acid Sequence KW - Anions -- metabolism KW - Isoenzymes -- genetics KW - Drosophila melanogaster -- enzymology KW - Hydrolysis KW - Isoenzymes -- metabolism KW - Binding Sites KW - Mutagenesis, Site-Directed KW - Naphthalenes -- metabolism KW - Malathion -- chemistry KW - Conserved Sequence KW - Kinetics KW - Acetylcholinesterase -- genetics KW - Spodoptera -- cytology KW - Amino Acid Substitution KW - Cell Line KW - Malathion -- metabolism KW - Insecticides -- metabolism KW - Diptera -- enzymology KW - Diptera -- genetics KW - Carboxylesterase -- genetics KW - Insecticides -- chemistry KW - Carboxylesterase -- metabolism KW - Carboxylesterase -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71769558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Insect+biochemistry+and+molecular+biology&rft.atitle=Hydrolysis+of+organophosphorus+insecticides+by+in+vitro+modified+carboxylesterase+E3+from+Lucilia+cuprina.&rft.au=Heidari%2C+R%3BDevonshire%2C+A+L%3BCampbell%2C+B+E%3BBell%2C+K+L%3BDorrian%2C+S+J%3BOakeshott%2C+J+G%3BRussell%2C+R+J&rft.aulast=Heidari&rft.aufirst=R&rft.date=2004-04-01&rft.volume=34&rft.issue=4&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Insect+biochemistry+and+molecular+biology&rft.issn=09651748&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-15 N1 - Date created - 2004-03-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effect of external stresses on protein conformation: a computer modelling study. AN - 71759068; 14574523 AB - The increasing use of digital technologies such as mobile phones has led to major health concerns about the effects of non-ionizing pulsed radiation exposure. We believe that the health implications of exposure to radiation cannot be fully understood without establishing the molecular mechanisms of biological effects of pulsed microwaves. We aim to establish methods for studying the molecular mechanisms of protein structural and energetic changes occurring due to external stresses related to non-ionizing radiation by using a combination of experimental and theoretical approaches. In this paper, we present the results from our fully atomistic simulation study of chemical and thermal stress response of a prototype protein, insulin. We performed a series of molecular dynamics simulations of insulin in solution under equilibrium conditions, under chemical stress (imitated by reducing the disulfide bonds in the protein molecule), and under short-lived thermal stress (imitated by increasing simulation temperature for up to 2 ns). The resultant protein conformational behaviour was analysed for various properties with the aim of establishing analysis routines for classification of protein unfolding pathways and associated molecular mechanisms. JF - European biophysics journal : EBJ AU - Budi, A AU - Legge, S AU - Treutlein, H AU - Yarovsky, I AD - Department of Applied Physics, RMIT University, GPO Box 2476V, 3001 Melbourne, Victoria, Australia. Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 121 EP - 129 VL - 33 IS - 2 SN - 0175-7571, 0175-7571 KW - Insulin KW - 0 KW - Proteins KW - Index Medicus KW - Software KW - Proteins -- chemistry KW - Computer Simulation KW - Algorithms KW - Dose-Response Relationship, Radiation KW - Proteins -- radiation effects KW - Hot Temperature KW - Models, Molecular KW - Radiation, Nonionizing KW - Insulin -- radiation effects KW - Protein Conformation -- radiation effects KW - Insulin -- chemistry KW - Models, Chemical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71759068?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+biophysics+journal+%3A+EBJ&rft.atitle=Effect+of+external+stresses+on+protein+conformation%3A+a+computer+modelling+study.&rft.au=Budi%2C+A%3BLegge%2C+S%3BTreutlein%2C+H%3BYarovsky%2C+I&rft.aulast=Budi&rft.aufirst=A&rft.date=2004-04-01&rft.volume=33&rft.issue=2&rft.spage=121&rft.isbn=&rft.btitle=&rft.title=European+biophysics+journal+%3A+EBJ&rft.issn=01757571&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-02-15 N1 - Date created - 2004-03-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Calcineurin and heat-shock proteins modulation in clenbuterol-induced hypertrophied rat skeletal muscles. AN - 71736155; 14758479 AB - To examine the changes in heat shock proteins (HSPs) and calcineurin (CaN), a calcium/calmodulin regulated protein phosphatase, in hypertrophied rat skeletal muscles, adult male Wistar rats were administered clenbuterol (CLB, 30 mg l(-1) in drinking water), a beta 2-agonist, for 4 weeks. Compared to controls, CLB-treated rats had significantly larger body (10%) and relative (to body weight) soleus (Sol, 16%), plantaris (Plt, 32%) and gastrocnemius (Gast, 27%) weights. Immunohistochemically classified fast fibers were hypertrophied in the Sol (64%), Plt (62%), and deep (d, 70%) and superficial (s, 44%) regions of the Gast, whereas slow fibers were hypertrophied only in the Plt (47%). The percentage of fast fibers in the Sol increased from 10% to 21%. The myosin heavy chain (MHC) isoform composition shifted from slow to fast in the Sol (increase in the percentage of type IIa MHC and de novo synthesis of type IIx MHC) and Gast-d (de novo synthesis of type IIb MHC) and to the faster isoforms in the Plt (increase in the percentage of type IIb MHC). Hsp72 and Hsp90 levels in CLB-treated rats were 52% and 50% lower in the Sol and 44 and 41% lower in the Gast-d, respectively, than in control rats. In control rats, the relative content of CaN was: Sol>Gast-d>Plt>Gast-s, and CLB treatment enhanced the CaN content by 1.4-, 1.2-, 5.0-, and 3.3-fold, respectively. These results indicate that the down-regulation of HSPs in the Sol and Gast-d was closely related to a decrease in the slow phenotype, and that the relative up-regulation of CaN among the muscles/regions was closely related to the selective hypertrophy of fast fibers in the CLB-treated rats. JF - Pflugers Archiv : European journal of physiology AU - Oishi, Yasu AU - Imoto, Kohjiro AU - Ogata, Tomonori AU - Taniguchi, Kouhachi AU - Matsumoto, Hisahiro AU - Fukuoka, Yoshiyuki AU - Roy, Roland R AD - Laboratory of Muscle Physiology, Faculty of Education, Kumamoto University, 860-8555 Kumamoto, Japan. oishi@gpo.kumamoto-u.ac.jp Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 114 EP - 122 VL - 448 IS - 1 SN - 0031-6768, 0031-6768 KW - Adrenergic beta-Agonists KW - 0 KW - Heat-Shock Proteins KW - Calcineurin KW - EC 3.1.3.16 KW - Phosphoprotein Phosphatases KW - Myosin Heavy Chains KW - EC 3.6.4.1 KW - Clenbuterol KW - XTZ6AXU7KN KW - Index Medicus KW - Rats KW - Animals KW - Blotting, Western KW - Electrophoresis, Polyacrylamide Gel KW - Drinking -- physiology KW - Rats, Wistar KW - Phosphoprotein Phosphatases -- metabolism KW - Hypertrophy -- metabolism KW - Hypertrophy -- chemically induced KW - Myosin Heavy Chains -- metabolism KW - Immunohistochemistry KW - Male KW - Heat-Shock Proteins -- metabolism KW - Muscle, Skeletal -- pathology KW - Calcineurin -- metabolism KW - Clenbuterol -- toxicity KW - Adrenergic beta-Agonists -- toxicity KW - Muscle, Skeletal -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71736155?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pflugers+Archiv+%3A+European+journal+of+physiology&rft.atitle=Calcineurin+and+heat-shock+proteins+modulation+in+clenbuterol-induced+hypertrophied+rat+skeletal+muscles.&rft.au=Oishi%2C+Yasu%3BImoto%2C+Kohjiro%3BOgata%2C+Tomonori%3BTaniguchi%2C+Kouhachi%3BMatsumoto%2C+Hisahiro%3BFukuoka%2C+Yoshiyuki%3BRoy%2C+Roland+R&rft.aulast=Oishi&rft.aufirst=Yasu&rft.date=2004-04-01&rft.volume=448&rft.issue=1&rft.spage=114&rft.isbn=&rft.btitle=&rft.title=Pflugers+Archiv+%3A+European+journal+of+physiology&rft.issn=00316768&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-12-07 N1 - Date created - 2004-03-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Humanitarian Crises in Ethiopia and Eritrea AN - 60676148; 200422374 AB - Following some details on the scope of the humanitarian crisis in Ethiopia & Eritrea, factors that contribute to its recurrence are considered. Drought, ensuing famine, & war are key causes that are underpinned by high population growth, heavy debt burdens, resource scarcity, economic mismanagement, poor governance, misplaced budgetary priorities, poor agricultural policies, abject poverty, poor infrastructure, lack of access to fertilizers & pesticides, & armed conflict. J. Zendejas JF - Mediterranean Quarterly AU - Dagne, Theodros AD - Congressional Research Service Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 38 EP - 46 VL - 15 IS - 2 SN - 1047-4552, 1047-4552 KW - Political Factors KW - Famine KW - Foreign Aid KW - Ethiopia KW - Economic Conditions KW - Crises KW - Natural Disasters KW - Eritrea KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60676148?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mediterranean+Quarterly&rft.atitle=Humanitarian+Crises+in+Ethiopia+and+Eritrea&rft.au=Dagne%2C+Theodros&rft.aulast=Dagne&rft.aufirst=Theodros&rft.date=2004-04-01&rft.volume=15&rft.issue=2&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Mediterranean+Quarterly&rft.issn=10474552&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Ethiopia; Eritrea; Crises; Famine; Natural Disasters; Foreign Aid; Economic Conditions; Political Factors ER - TY - JOUR T1 - Investigations into the pyrolytic behaviour of coal/biomass blends using thermogravimetric analysis AN - 20729409; 5793461 AB - Investigations into the pyrolytic behaviour during co-pyrolysis of coal, biomass materials and coal/biomass blends prepared at different ratios (10:90, 20:80, 30:70 and 50:50) have been conducted using a thermogravimetric analysis (TGA) apparatus. The coal sample selected was Collie sub-bituminous coal from Western Australia, while wood waste (WW) and wheat straw (WS) were used as biomass samples. Three thermal events were identified during the pyrolysis. The first two were dominated by the biomass pyrolysis, while the third was linked to the coal pyrolysis, which occurred at much higher temperatures. No interactions were seen between the coal and biomass during co-pyrolysis. The pyrolytic characteristics of the blends followed those of the parent fuels in an additive manner. Among the tested blends, 20:80 blends showed the lowest activation energies of 90.9 and 78.7 kJ mol super(-1) for coal/WW and coal/WS blends respectively. The optimum blend ratio for pyrolysis of coal/WS was 50:50 with a high degradation rate in all the thermal events and a higher mass loss over the course of the co-pyrolysis compared to coal/WW blends examined. The reaction orders in these experiments were in the range of 0.21-1.60, thus having a significant effect on the overall reaction rate. Besides the pyrolysis of coal alone, the 50:50 coal/biomass blends had the highest reaction rate, ranging 1 x 10 super(9)-2 x 10 super(9) min super(-1). The experimental results may provide useful data for power generation industries for the development of co-firing options with biomass. JF - Bioresource Technology AU - Vuthaluru, H B AD - Department of Chemical Engineering, Curtin University of Technology, GPO Box 1987, Perth, WA 6845, Australia, h.vuthaluru@exchange.curtin.edu.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 187 EP - 195 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 92 IS - 2 SN - 0960-8524, 0960-8524 KW - Biotechnology and Bioengineering Abstracts KW - Coal KW - Biomass KW - Thermal degradation KW - Co-pyrolysis co-firing KW - Pyrolysis KW - Temperature effects KW - Triticum aestivum KW - Fuels KW - Wastes KW - Straw KW - W 30950:Waste Treatment & Pollution Clean-up UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20729409?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioresource+Technology&rft.atitle=Investigations+into+the+pyrolytic+behaviour+of+coal%2Fbiomass+blends+using+thermogravimetric+analysis&rft.au=Vuthaluru%2C+H+B&rft.aulast=Vuthaluru&rft.aufirst=H&rft.date=2004-04-01&rft.volume=92&rft.issue=2&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Bioresource+Technology&rft.issn=09608524&rft_id=info:doi/10.1016%2Fj.biortech.2003.08.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Pyrolysis; Fuels; Wastes; Straw; Coal; Biomass; Triticum aestivum DO - http://dx.doi.org/10.1016/j.biortech.2003.08.008 ER - TY - JOUR T1 - Ecological filtering of exotic plants in an Australian sub-alpine environment AN - 19770081; 5902896 AB - We investigated some of the factors influencing exotic invasion of native sub-alpine plant communities at a site in southeast Australia. Structure, floristic composition and invasibility of the plant communities and attributes of the invasive species were studied. To determine the plant characteristics correlated with invasiveness, we distinguished between roadside invaders, native community invaders and non-invasive exotic species, and compared these groups across a range of traits including functional group, taxonomic affinity, life history, mating system and morphology. Poa grasslands and Eucalyptus-Poa woodlands contained the largest number of exotic species, although all communities studied appeared resilient to invasion by most species. Most community invaders were broad-leaved herbs while roadside invaders contained both herbs and a range of grass species. Over the entire study area the richness and cover of native and exotic herbaceous species were positively related, but exotic herbs were more negatively related to cover of specific functional groups (e.g. trees) than native herbs. Compared with the overall pool of exotic species, those capable of invading native plant communities were disproportionately polycarpic, Asteracean and cross-pollinating. Our data support the hypothesis that strong ecological filtering of exotic species generates an exotic assemblage containing few dominant species and which functionally converges on the native assemblage. These findings contrast with those observed in the majority of invaded natural systems. We conclude that the invasion of closed sub-alpine communities must be viewed in terms of the unique attributes of the invading species, the structure and composition of the invaded communities and the strong extrinsic physical and climatic factors typical of the sub-alpine environment. Nomenclature: Australian Plant Name Index (APNI); Abbreviations: KNP = Kosciuszko National Park; MRPP = Multi response permutation procedure; VE = Variance explained. JF - Journal of Vegetation Science AU - Godfree, R AU - Lepschi, B AU - Mallinson, D AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT, Australia, 2601, lepschi@csiro.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 227 EP - 236 PB - International Association of Vegetation Science VL - 15 IS - 2 SN - 1100-9233, 1100-9233 KW - Ecology Abstracts; Sustainability Science Abstracts KW - Grasslands KW - Mating KW - Life history KW - Roadsides KW - Poa KW - Plant communities KW - Sub-alpine environments KW - Introduced species KW - Herbs KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19770081?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Vegetation+Science&rft.atitle=Ecological+filtering+of+exotic+plants+in+an+Australian+sub-alpine+environment&rft.au=Godfree%2C+R%3BLepschi%2C+B%3BMallinson%2C+D&rft.aulast=Godfree&rft.aufirst=R&rft.date=2004-04-01&rft.volume=15&rft.issue=2&rft.spage=227&rft.isbn=&rft.btitle=&rft.title=Journal+of+Vegetation+Science&rft.issn=11009233&rft_id=info:doi/10.1043%2F1100-9233%282004%29015%280227%3AEFOEPI%292.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=1100-9233&volume=15&page=227 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Poa; Introduced species; Herbs; Plant communities; Roadsides; Sub-alpine environments; Mating; Life history; Grasslands DO - http://dx.doi.org/10.1043/1100-9233(2004)015(0227:EFOEPI)2.0.CO;2 ER - TY - JOUR T1 - Generation of SUMO-1 modified proteins in E. coli: towards understanding the biochemistry/structural biology of the SUMO-1 pathway AN - 19714737; 7492167 AB - Here, we developed a binary vector system that introduces a synthetic SUMO-1 conjugation pathway into Escherichia coli and demonstrated that large amounts of sumoylated Ran GTPase activating protein 1 C-terminal region (RanGAP1-C2), Ran binding protein 2 internal repeat domain, p53 and promyelocytic leukemia were efficiently produced. The sumoylated recombinant RanGAP1-C2 appeared to retain the in vivo properties, since it was specifically sumoylated at lysine 517 as expected from in vivo studies. Our findings indicate the establishment of a biosynthetic route for producing large amounts of sumoylated recombinant proteins that will open up new avenues for studying the biochemical and structural aspects of the SUMO-1 modification pathway. JF - FEBS Letters AU - Uchimura, Yasuhiro AU - Nakao, Mitsuyoshi AU - Saitoh, Hisato AD - Department of Regeneration Medicine, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan, hisa@gpo.kumamoto-u.ac.jp Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 85 EP - 90 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 564 IS - 1-2 SN - 0014-5793, 0014-5793 KW - Microbiology Abstracts B: Bacteriology KW - Author Keywords: Posttranslational modification KW - SUMO-1 KW - Ran GTPase activating protein 1 KW - Ran binding protein 2 KW - Promyelocytic leukemia KW - p53 KW - Escherichia coli KW - Lysine KW - Promyeloid leukemia KW - Guanosinetriphosphatase KW - p53 protein KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19714737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEBS+Letters&rft.atitle=Generation+of+SUMO-1+modified+proteins+in+E.+coli%3A+towards+understanding+the+biochemistry%2Fstructural+biology+of+the+SUMO-1+pathway&rft.au=Uchimura%2C+Yasuhiro%3BNakao%2C+Mitsuyoshi%3BSaitoh%2C+Hisato&rft.aulast=Uchimura&rft.aufirst=Yasuhiro&rft.date=2004-04-01&rft.volume=564&rft.issue=1-2&rft.spage=85&rft.isbn=&rft.btitle=&rft.title=FEBS+Letters&rft.issn=00145793&rft_id=info:doi/10.1016%2FS0014-5793%2804%2900321-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Promyeloid leukemia; Lysine; p53 protein; Guanosinetriphosphatase; Escherichia coli DO - http://dx.doi.org/10.1016/S0014-5793(04)00321-7 ER - TY - JOUR T1 - Can the Important Bird Area approach improve the Antarctic Protected Area System? AN - 19404476; 8710578 AB - The selection of sites that comprise the existing network of Antarctic protected areas has been largely ad hoc, driven by national interests rather than concerted efforts to ensure systematic and representative coverage of the Antarctic environment. Consequently there are gaps in coverage of all major ecosystems, in particular areas kept inviolate from human activity, inland lakes, and marine protected areas. Annex V of the 1991 Protocol on Environmental Protection to the Antarctic Treaty provides a list of values to be protected within a network of Antarctic Specially Protected Areas (ASPAs), but provides no quantitative methods for site identification and prioritisation. The Antarctic Important Bird Area (IBA) Inventory is a joint initiative of BirdLife International and the Scientific Committee on Antarctic Research Group of Experts on Birds (formerly the Bird Biology Subcommittee). The Antarctic IBA Inventory has identified 119 candidate IBAs, 97 of which are not currently protected as ASPAs. The IBA Inventory can improve the Antarctic Protected Area System (PAS) in that it provides a method by which to identify and prioritise sites for their potential inclusion in the Antarctic PAS. JF - Polar Record AU - Harris, Jane W AU - Woehler, Eric J AD - Institute of Antarctic and Southern Ocean Studies, University of Tasmania, GPO Box 252-77, Hobart, Tasmania 7001, Australia, eric.woehler@aad.gov.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 97 EP - 105 PB - Cambridge University Press, The Edinburgh Building, VL - 40 IS - 2 SN - 0032-2474, 0032-2474 KW - Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts; Sustainability Science Abstracts KW - Marine KW - Inventories KW - Ecosystems KW - marine protected areas KW - committees KW - Man-induced effects KW - Environmental protection KW - Joints KW - Aves KW - protected areas KW - Lakes KW - Nature conservation KW - Marine parks KW - Cadmium KW - Human factors KW - Q5 08523:Conservation, wildlife management and recreation KW - O 4090:Conservation and Environmental Protection KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08121:Law, policy, economics and social sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19404476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Polar+Record&rft.atitle=Can+the+Important+Bird+Area+approach+improve+the+Antarctic+Protected+Area+System%3F&rft.au=Harris%2C+Jane+W%3BWoehler%2C+Eric+J&rft.aulast=Harris&rft.aufirst=Jane&rft.date=2004-04-01&rft.volume=40&rft.issue=2&rft.spage=97&rft.isbn=&rft.btitle=&rft.title=Polar+Record&rft.issn=00322474&rft_id=info:doi/10.1017%2FS0032247403003322 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Marine parks; Nature conservation; Man-induced effects; Environmental protection; Inventories; Lakes; Joints; Aves; protected areas; Ecosystems; marine protected areas; committees; Cadmium; Human factors; Marine DO - http://dx.doi.org/10.1017/S0032247403003322 ER - TY - JOUR T1 - Biogeochemical marine ecosystem models II: the effect of physiological detail on model performance AN - 19399641; 5859033 AB - The level of detail required to efficiently capture system dynamics in ecosystem models has not been well defined. To this end an ecosystem model of a generalised temperate bay, Bay Model 2 (BM2), was constructed. It is a trophically diverse biogeochemical model built using the functional groups from another ecosystem model, the Integrated Generic Bay Ecosystem Model (IGBEM) and the general framework from a model of Port Phillip Bay (PPB), Australia. BM2 captures the essential features of real marine systems, it is also capable of reproducing realistic levels of biomass and conforms with known ecological relationships. The model's performance is not as good for some of the poorly known groups (like infauna) or when environmental conditions undergo extreme change. Despite this, the overall performance of BM2 indicated, it is as capable of representing systems as accurately as more physiologically detailed ecosystem models, such as IGBEM. This shows that physiological detail is not always required and that simpler formulations, such as those employed in BM2, are generally adequate for learning and general predictive purposes. This is important because, in comparison with IGBEM, BM2 uses substantially fewer parameters and has lower development, computation and maintenance costs. JF - Ecological Modelling AU - Fulton, E A AU - Parslow, J S AU - Smith, ADM AU - Johnson, C R AD - CSIRO Division of Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, beth.fulton@csiro.au Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 371 EP - 406 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 173 IS - 4 SN - 0304-3800, 0304-3800 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Prediction KW - Meiobenthos KW - PSE, Australia, Victoria, Port Phillip Bay KW - Interspecific relationships KW - Marine environment KW - Biogeochemistry KW - Environmental conditions KW - Ecosystem models KW - Modelling KW - Q1 08482:Ecosystems and energetics KW - Q2 09181:General KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19399641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Biogeochemical+marine+ecosystem+models+II%3A+the+effect+of+physiological+detail+on+model+performance&rft.au=Fulton%2C+E+A%3BParslow%2C+J+S%3BSmith%2C+ADM%3BJohnson%2C+C+R&rft.aulast=Fulton&rft.aufirst=E&rft.date=2004-04-01&rft.volume=173&rft.issue=4&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.09.024 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-01-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Prediction; Meiobenthos; Interspecific relationships; Biogeochemistry; Environmental conditions; Modelling; Marine environment; Ecosystem models; PSE, Australia, Victoria, Port Phillip Bay DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.09.024 ER - TY - JOUR T1 - Distinguishing sources of base cations in irrigated and natural soils: evidence from strontium isotopes AN - 17767456; 5927941 AB - Strontium isotope ratios ( super(87)Sr/ super(86)Sr) of soil solids, soil cation extracts, irrigation water and plant material are used to determine strontium and therefore cation sources and fluxes in irrigated and natural soil-plant systems. Strontium isotopes of soil solids from four soil profiles (two irrigated vineyard soils and two 'natural' profiles from nearby reserves) show large differences between soil horizons with depth. These differences are not reflected in super(87)Sr/ super(86)Sr ratios of soil labile cations, which show both little variation down-profile and much lower ratios than soil solids. In the undisturbed, natural soil profiles, labile cation super(87)Sr/ super(86)Sr ratios are close to the ratio of modern seawater, indicating that solutes of marine origin from precipitation are the primary input of strontium (and calcium) to the labile cation pool. In the irrigated soil profiles, super(87)Sr / super(86)Sr ratios of labile cations are consistently shifted towards that of the irrigation water. Mass-balance calculations using super(87)Sr/ super(86)Sr ratios of the different inputs to the labile cation pool indicate more than 90% of labile strontium is derived from precipitation solutes in unirrigated soils, and up to 44% from irrigation water solutes as an additional source in irrigated soils. The super(87)Sr/ super(86)Sr ratios of grapes grown in irrigated soils match precisely with those of the labile soil cations, demonstrating that cation nutrients are drawn wholly from the labile cation pool and have the same mix of precipitation, irrigation, and soil solid sources. The super(87)Sr/ super(86)Sr ratios of grapes grown in the irrigated soils may therefore vary over time depending on (1) the changing mix of irrigation water and local precipitation and (2) potential change to irrigation water. These findings suggest limitations to the use of strontium isotopes in the tracing of grapes and wines to their soil of origin. JF - Biogeochemistry AU - Green, G P AU - Bestland, E A AU - Walker, G S AD - Earth Sciences, SoCPES, Flinders University, GPO Box 2100, Adelaide 5001, Australia Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 199 EP - 225 PB - Kluwer Academic Publishers VL - 68 IS - 2 SN - 0168-2563, 0168-2563 KW - Water Resources Abstracts KW - Calcium KW - Biogeochemistry KW - Local Precipitation KW - Pools KW - Solids KW - Nutrients KW - Soil Horizons KW - Solutes KW - Cations KW - Strontium KW - Irrigation Water KW - Soil Profile KW - SW 0880:Chemical processes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17767456?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biogeochemistry&rft.atitle=Distinguishing+sources+of+base+cations+in+irrigated+and+natural+soils%3A+evidence+from+strontium+isotopes&rft.au=Green%2C+G+P%3BBestland%2C+E+A%3BWalker%2C+G+S&rft.aulast=Green&rft.aufirst=G&rft.date=2004-04-01&rft.volume=68&rft.issue=2&rft.spage=199&rft.isbn=&rft.btitle=&rft.title=Biogeochemistry&rft.issn=01682563&rft_id=info:doi/10.1023%2FB%3ABIOG.0000025743.34079.d3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Solutes; Calcium; Cations; Biogeochemistry; Local Precipitation; Pools; Nutrients; Solids; Irrigation Water; Strontium; Soil Horizons; Soil Profile DO - http://dx.doi.org/10.1023/B:BIOG.0000025743.34079.d3 ER - TY - JOUR T1 - Benthic fluxes of nitrogen in the tidal reaches of a turbid, high-nitrate sub-tropical river AN - 17594534; 5932143 AB - Benthic fluxes of dissolved inorganic nitrogen (NO3 super(-) and NH4 super(+)), dissolved organic nitrogen (DON), N2 (denitrification), O2 and TCO2 were measured in the tidal reaches of the Bremer River, south east Queensland, Australia. Measurements were made at three sites during summer and winter. Fluxes of NO3 super(-) were generally directed into the sediments at rates of up to -225 mu molNm super(-2)h super(-1). NH4 super(+) was mostly taken up by the sediments at rates of up to -52 mu molNm super(-2)h super(-1), its ultimate fate probably being denitrification. DON fluxes were not significant during winter. During summer, fluxes of DON were observed both into (-105 mu molm super(-2)h super(-1)) and out of (39 mu molm super(-2)h super(-1)) the sediments. Average N2 fluxes at all sampling sites were similar during summer (162 mu molNm super(-2)h super(-1)) and winter (153 mu molNm super(-2)h super(-1)). Denitrification was fed both by nitrification within the sediment and NO3 super(-) from the water column. Sediment respiration rates played an important role in the dynamics of nitrification and denitrification. NO3 super(-) fluxes were significantly related to TCO2 fluxes (p0.01), with a release of NO3 super(-) from the sediment only occurring at respiration rates below 1000 mu molCm super(-2)h super(-1). Rates of denitrification increased with respiration up to TCO2 fluxes of 1000 mu molCm super(-2)h super(-1). At sediment respiration rates above 1000 mu molCm super(-2)h super(-1), denitrification rates increased less rapidly with respiration in winter and declined during summer. On a monthly basis denitrification removed about 9% of the total nitrogen and 16% of NO3 super(-) entering the Bremer River system from known point sources. This is a similar magnitude to that estimated in other tidal river systems and estuaries receiving similar nitrogen loads. During flood events the amount of NO3 super(-) denitrified dropped to about 6% of the total river NO3 super(-) load. JF - Estuarine, Coastal and Shelf Science AU - Cook, P L AU - Eyre, B D AU - Leeming, R AU - Butler, E C AD - University of Tasmania, GPO Box 252-75, Hobart, Tasmania 7001, Australia, pcook@mpi-bremen.de Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 675 EP - 685 PB - Elsevier Ltd VL - 59 IS - 4 SN - 0272-7714, 0272-7714 KW - Sediment respiration rates KW - Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts; Aqualine Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 1: Biological Sciences & Living Resources KW - M2 551.468:Coastal Oceanography (551.468) KW - Q2 02183:Physics and chemistry KW - O 1080:Multi-disciplinary Studies KW - Q1 01482:Ecosystems and energetics KW - AQ 00002:Water Quality KW - SW 0890:Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17594534?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Benthic+fluxes+of+nitrogen+in+the+tidal+reaches+of+a+turbid%2C+high-nitrate+sub-tropical+river&rft.au=Cook%2C+P+L%3BEyre%2C+B+D%3BLeeming%2C+R%3BButler%2C+E+C&rft.aulast=Cook&rft.aufirst=P&rft.date=2004-04-01&rft.volume=59&rft.issue=4&rft.spage=675&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2003.11.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-04-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.ecss.2003.11.011 ER - TY - JOUR T1 - Experimental investigation of ultra-fine particle size distribution near a busy road AN - 16173000; 5860441 AB - In this paper, evolution of the size distribution of fine and ultra-fine particles emitted from vehicles on a busy road is investigated experimentally. In particular, several different modes (distinct maxima) of the particle size distribution are investigated as a function of the distance from the road. An unusual and complex evolution of these modes is discovered. In particular, it is demonstrated that some of the modes tend to shift towards smaller particle size, which has never been reported previously. Complex correlation between the modes is determined experimentally. In addition, for the first time, the total number concentration is clearly shown to go through a significant maximum at some distance from the road. This could have significant influence on the assessment of exposure to fine and ultra-fine particles in the vicinity of busy roads. JF - Atmospheric Environment AU - Gramotnev, G AU - Ristovski, Z AD - International Laboratory for Air Quality and Health, School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane QLD 4001, Australia, z.ristovski@qut.edu.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 1767 EP - 1776 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 38 IS - 12 SN - 1352-2310, 1352-2310 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Particle size KW - Air pollution KW - Particle size distribution KW - Combustion products KW - Motor vehicles KW - Correlation analysis KW - Atmospheric pollution by road vehicles KW - Highways KW - Particulate atmospheric pollution KW - Exhaust emissions KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16173000?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Experimental+investigation+of+ultra-fine+particle+size+distribution+near+a+busy+road&rft.au=Gramotnev%2C+G%3BRistovski%2C+Z&rft.aulast=Gramotnev&rft.aufirst=G&rft.date=2004-04-01&rft.volume=38&rft.issue=12&rft.spage=1767&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2003.12.028 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2004-05-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Particle size distribution; Correlation analysis; Atmospheric pollution by road vehicles; Particulate atmospheric pollution; Air pollution; Particle size; Combustion products; Motor vehicles; Highways; Exhaust emissions DO - http://dx.doi.org/10.1016/j.atmosenv.2003.12.028 ER - TY - JOUR T1 - Arsenic-Induced Enhancement of Ultraviolet Radiation Carcinogenesis in Mouse Skin: a DoseResponse Study AN - 14699551; 10660725 JF - Environmental Health Perspectives AU - Burns, Fredric J AU - Uddin, Ahmed N AU - Wu, Feng AU - Nadas, Arthur AU - Rossman, Toby G Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 599 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ULTRAVIOLET RADIATION KW - CARCINOGENIC MECHANISMS KW - ARSENIC KW - CARCINOGENIC AGENTS KW - WATER, DRINKING KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699551?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Arsenic-Induced+Enhancement+of+Ultraviolet+Radiation+Carcinogenesis+in+Mouse+Skin%3A+a+Dose%26lt%3BND%26gt%3BResponse+Study&rft.au=Burns%2C+Fredric+J%3BUddin%2C+Ahmed+N%3BWu%2C+Feng%3BNadas%2C+Arthur%3BRossman%2C+Toby+G&rft.aulast=Burns&rft.aufirst=Fredric&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=599&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ULTRAVIOLET RADIATION; CARCINOGENIC MECHANISMS; CARCINOGENIC AGENTS; ARSENIC; RODENTS; WATER, DRINKING ER - TY - JOUR T1 - Polychlorinated Biphenyls (PCBs) Exert Thyroid Hormone-Like Effects in the Fetal Rat Brain But Do Not Bind to Thyroid Hormone Receptors AN - 14699515; 10660712 AB - Timed-pregnant SpragueDawley rats were provided daily with a wafer dosed with Aroclor 1254 on gestational days 616. The dams were then euthanized, and fetuses were examined for effects on thyroid hormone signaling in the developing brain. Aroclor 1254 was found to significantly reduce serum thyroid hormone levels in pregnant rats, but PCB exposure upregulated the expression of genes that are regulated positively by thyroid hormones. Fetuses derived from Aroclor 1254-treated dams exhibited a significant increase in RC3/neurogranin and Oct-1 expression, indicating that PCBs produced thyroid hormone-like effects in the fetal brain. When a number of PCB congeners and specific metabolites were tested for their ability to bind to thyroid hormone receptors using a well-established binding assay, neither the parent PCB congeners or their metabolites significantly displaced triiodothyronine from the rat hepatic nuclei. JF - Environmental Health Perspectives AU - Gauger, Kelly J AU - Kato, Yoshihisa AU - Haraguchi, Koichi AU - Lehmler, Hans-Joachim AU - Robertson, Larry W AU - Bansal, Ruby AU - Zoeller, RThomas Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 516 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - NEUROTOXICITY KW - HORMONAL EFFECTS KW - AROCLOR KW - REPRODUCTION, ANIMAL KW - THYROID FUNCTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699515?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Polychlorinated+Biphenyls+%28PCBs%29+Exert+Thyroid+Hormone-Like+Effects+in+the+Fetal+Rat+Brain+But+Do+Not+Bind+to+Thyroid+Hormone+Receptors&rft.au=Gauger%2C+Kelly+J%3BKato%2C+Yoshihisa%3BHaraguchi%2C+Koichi%3BLehmler%2C+Hans-Joachim%3BRobertson%2C+Larry+W%3BBansal%2C+Ruby%3BZoeller%2C+RThomas&rft.aulast=Gauger&rft.aufirst=Kelly&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=516&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AROCLOR; NEUROTOXICITY; POLYCHLORINATED BIPHENYLS; HORMONAL EFFECTS; REPRODUCTION, ANIMAL; THYROID FUNCTION ER - TY - JOUR T1 - Cancer Risk and Parental Pesticide Application in Children of Agricultural Health Study Participants AN - 14699352; 10660731 AB - The Agricultural Health Study, conducted in Iowa and North Carolina, examined the relationship between pesticide exposure among licensed pesticide applicators and adult chronic diseases. Using the data generated, cancer risk was examined in this study among children of the pesticide applicators. Cancer cases among the children were identified both retrospectively and prospectively after parental enrollment in the initial study between 1993 and 1997. A standardized incidence ratio was generated to compare the observed number of childhood cancer cases to the expected number. When tumor-specific standardized incidence ratios were generated, more lymphoma cases were observed in Iowa than expected, and more cases were also observed for brain tumors, neurobastoma, retinoblastoma, Wilms tumor, and bone tumors. Among the lymphoma subtypes, an increased incidence of Hodgkin's lymphoma, Burkitt's lymphoma, and non-Hodgkin's lymphoma was observed. Children whose mothers applied pesticides more than 5 d/yr had a lower risk of cancer than did children whose mother reported never mixing or applying pesticides, and no significant associations were noted between maternal application of specific pesticides and childhood cancer risk. JF - Environmental Health Perspectives AU - Flower, Kori B AU - Hoppin, Jane A AU - Lynch, Charles F AU - Blair, Aaron AU - Knott, Charles AU - Shore, David L AU - Sandler, Dale P Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 631 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - NORTH CAROLINA KW - PESTICIDE APPLICATION KW - IOWA KW - HEALTH SAFETY, OCCUPATIONAL KW - PATHOLOGY, CHILDREN KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699352?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cancer+Risk+and+Parental+Pesticide+Application+in+Children+of+Agricultural+Health+Study+Participants&rft.au=Flower%2C+Kori+B%3BHoppin%2C+Jane+A%3BLynch%2C+Charles+F%3BBlair%2C+Aaron%3BKnott%2C+Charles%3BShore%2C+David+L%3BSandler%2C+Dale+P&rft.aulast=Flower&rft.aufirst=Kori&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=631&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; IOWA; CANCER RISK; PATHOLOGY, CHILDREN; NORTH CAROLINA; PESTICIDE EXPOSURE; PESTICIDE APPLICATION ER - TY - JOUR T1 - Cognitive Deficits and Magnetic Resonance Spectroscopy in Adult Monozygotic Twins with Lead Poisoning AN - 14699315; 10660729 JF - Environmental Health Perspectives AU - Weisskopf, Marc G AU - Hu, Howard AU - Mulkern, Robert V AU - White, Roberta AU - Aro, Antonio AU - Oliveira, Steve AU - Wright, Robert O Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 620 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - SPECTROSCOPY KW - LEAD POISONING KW - PATHOLOGY, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cognitive+Deficits+and+Magnetic+Resonance+Spectroscopy+in+Adult+Monozygotic+Twins+with+Lead+Poisoning&rft.au=Weisskopf%2C+Marc+G%3BHu%2C+Howard%3BMulkern%2C+Robert+V%3BWhite%2C+Roberta%3BAro%2C+Antonio%3BOliveira%2C+Steve%3BWright%2C+Robert+O&rft.aulast=Weisskopf&rft.aufirst=Marc&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=620&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; SPECTROSCOPY; LEAD POISONING; PATHOLOGY, HUMAN ER - TY - JOUR T1 - Blood Organic Mercury and Dietary Mercury Intake: National Health and Nutrition Examination Survey, 1999 and 2000 AN - 14699288; 10660720 AB - Data obtained from participants in the 19992000 National Health and Nutrition Examination Survey were used to examine the association between blood total mercury and calculated organic Hg intake of methylmercury (MeHg) from fish and shellfish. Mercury concentrations in marine, estuarine, and freshwater fish were obtained from selected databases, and Hg intakes from fish were estimated by combining data on Hg concentrations in fish species with reported quantities and types of fish species consumed. Projected month-long estimates of fish/shellfish intake and Hg exposure were developed for individual adult female participants. Results revealed that, as blood total Hg concentrations increased, the fraction that was MeHg increased. When Hg intake was consistent and prolonged, there was a well-defined association between Hg in blood and Hg in diet. Blood total Hg concentrations were higher among women aged 3049 yr than among younger women. All fish/shellfish consumption was a significant predictor of blood total Hg and blood organic Hg. JF - Environmental Health Perspectives AU - Mahaffey, Kathryn R AU - Clickner, Robert P AU - Bodurow, Catherine C Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 562 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - METHYLMERCURY KW - FISH KW - DIET KW - BIOACCUMULATION, HUMAN KW - SHELLFISH KW - BLOOD ANALYSIS KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699288?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Blood+Organic+Mercury+and+Dietary+Mercury+Intake%3A+National+Health+and+Nutrition+Examination+Survey%2C+1999+and+2000&rft.au=Mahaffey%2C+Kathryn+R%3BClickner%2C+Robert+P%3BBodurow%2C+Catherine+C&rft.aulast=Mahaffey&rft.aufirst=Kathryn&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=562&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SHELLFISH; BLOOD ANALYSIS; METHYLMERCURY; FISH; DIET; BIOACCUMULATION, HUMAN; MERCURY ER - TY - JOUR T1 - Understanding Sex Differences in Environmental Health: a Thought Leaders' Roundtable AN - 14698751; 10660726 AB - The Society for Women's Health Research convened a thought leaders' roundtable in October 2002 to discuss recent advances in environmental health research, focusing on findings that explain sex differences in response to environmental exposures. The participants presented research from a broad spectrum of disciplines ranging from immunology to behavior. The findings from the roundtable are summarized here in the following areas: the environment and the immune system, heavy metals and steroid receptors, cancer and the environment, endocrine disruptors, and genomics. Recommendations for further research in this area are proposed. JF - Environmental Health Perspectives AU - Keitt, Sarah K AU - Fagan, Thomas F AU - Marts, Sherry A Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 604 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - HORMONAL EFFECTS KW - IMMUNE RESPONSE KW - CARCINOGENIC MECHANISMS KW - PHYSIOLOGICAL EFFECTS, HUMAN KW - HEAVY METALS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14698751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Understanding+Sex+Differences+in+Environmental+Health%3A+a+Thought+Leaders%27+Roundtable&rft.au=Keitt%2C+Sarah+K%3BFagan%2C+Thomas+F%3BMarts%2C+Sherry+A&rft.aulast=Keitt&rft.aufirst=Sarah&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=604&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 44 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; CARCINOGENIC MECHANISMS; PHYSIOLOGICAL EFFECTS, HUMAN; HEAVY METALS; HORMONAL EFFECTS; GENETICS, HUMAN; IMMUNE RESPONSE ER - TY - JOUR T1 - The Protective Effect of delta -Aminolevulinic Acid Dehydratase 1-2 and 2-2 Isozymes Against Blood Lead with Higher Hematologic Parameters AN - 14698728; 10660715 AB - Lead inhibits three enzymes- delta -aminolevulinic acid dehydratase (ALAD), coporphyrinogen oxidase, and ferrochelatase-in the heme-synthesis pathway, but the effects on ALAD are most profound. Blood samples were collected from 1219 male Pb workers from Korea, and differences of hematologic parameters by ALAD genotype were evaluated. All blood samples were analyzed for Pb, zinc protoporphyrin (ZPP), hemoglobin, serum iron, and ALAD genotypes. Compared with nonlead workers, Pb workers exhibited a higher mean blood Pb level and a higher mean ZPP level, but 90% of both groups were homozygous for the ALAD 1-1 genotype. Subjects with ALAD 1-2 or 2-2 isozymes had significantly higher hemoglobin levels when blood Pb and serum Fe levels and other confounding covariates were controlled. Logistics regression revealed that the ALAD genotype was associated with the presence of anemia, especially subjects with ALAD 1-1. JF - Environmental Health Perspectives AU - Kim, Hee-Seon AU - Lee, Sung-Soo AU - Lee, Gap-Soo AU - Hwangbo, Young AU - Ahn, Kyu-Dong AU - Lee, Byung-Kook Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 538 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - ENZYMES KW - BLOOD LEAD LEVEL KW - KOREA, SOUTH KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14698728?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Protective+Effect+of+delta+-Aminolevulinic+Acid+Dehydratase+1-2+and+2-2+Isozymes+Against+Blood+Lead+with+Higher+Hematologic+Parameters&rft.au=Kim%2C+Hee-Seon%3BLee%2C+Sung-Soo%3BLee%2C+Gap-Soo%3BHwangbo%2C+Young%3BAhn%2C+Kyu-Dong%3BLee%2C+Byung-Kook&rft.aulast=Kim&rft.aufirst=Hee-Seon&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=538&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; ENZYMES; BLOOD LEAD LEVEL; KOREA, SOUTH; GENETICS, HUMAN ER - TY - JOUR T1 - Enhancing Effect of the Endocrine Disruptor para-Nonylphenol on the Generation of Reactive Oxygen Species in Human Blood Neutrophils AN - 14698160; 10660718 AB - The effect of para-nonylphenol (NP) on reactive oxygen species-producible immunocompetent cells, especially neutrophils, in human venous blood was studied. The human venous blood samples were obtained from nonsmoking healthy male donors, and neutrophils were isolated. The assay protocol for reactive oxygen species generation in human neutrophils and whole blood is outlined. Results showed that when various amounts of NP were added exogenously to human neutrophils, a luminol-dependent chemiluminescence was generated in a dose-dependent manner over the NP range 550 mu M. Use of reactive oxygen species-scavenging enzymes showed that NP caused the generation of superoxide anion and hydrogen peroxide. The mitochondrial function inhibitor, potassium cyanide, did not show significant effects on NP-induced reactive oxygen species generation, but nicotinamide adenine dinucleotide phosphate-dependent oxidase and myeloperoxidase, which are reactive oxygen species-generating enzymes, were highly expressed, and inhibitors against the enzymes exhibited remarkable suppression against NP-induced reactive oxygen species generation. A dose-dependent reactive oxygen species generation by NP was observed in whole blood, but the dose concentrations were relatively high compared with those of neutrophils alone. JF - Environmental Health Perspectives AU - Okai, Yasuji AU - Sato, Eisuke F AU - Higashi-Okai, Kiyoka AU - Inoue, Masayasu Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 553 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - ANTIOXIDANTS KW - PHENOL KW - OXIDANT STRESS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14698160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Enhancing+Effect+of+the+Endocrine+Disruptor+para-Nonylphenol+on+the+Generation+of+Reactive+Oxygen+Species+in+Human+Blood+Neutrophils&rft.au=Okai%2C+Yasuji%3BSato%2C+Eisuke+F%3BHigashi-Okai%2C+Kiyoka%3BInoue%2C+Masayasu&rft.aulast=Okai&rft.aufirst=Yasuji&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=553&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; PHENOL; ANTIOXIDANTS; OXIDANT STRESS ER - TY - JOUR T1 - Reporting Pesticide Assessment Results to Farmworker Families: Development, Implementation, and Evaluation of a Risk Communication Strategy AN - 14698043; 10660732 AB - The La Familia Study is a community-based participatory research project designed to develop, implement, and evaluate a lay health advisor intervention to reduce pesticide exposure among families of migrant and seasonal farm workers in North Carolina and Virginia. Here, development of the communication strategy is described, which involved three steps: listing of the expected challenges by environmental health scientists in delivering results and risk information, exploring other scientists and community-based participatory research projects for existing examples of communication materials and plans, and interviewing community members to learn what they wanted to know about the results. Ultimately, a script was drafted that included the material to be presented that suggested explanations along with questions to elicit indicators of comprehension. The final information focused on actions the families could take to reduce exposure. Implementation and assessment of the communication strategy are detailed, showing that it was possible to convey adequately the complex scientific findings in a way that was useful and accessible to persons without a scientific background or much formal education. JF - Environmental Health Perspectives AU - Quandt, Sara A AU - Doran, Alicia M AU - Rao, Pamela AU - Hoppin, Jane A AU - Snively, Beverly M AU - Arcury, Thomas A Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 636 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ENV JUSTICE KW - MINORITIES KW - CHEMICAL CONTAMINATION CONTROL KW - INFORMATION, ENV KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14698043?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Reporting+Pesticide+Assessment+Results+to+Farmworker+Families%3A+Development%2C+Implementation%2C+and+Evaluation+of+a+Risk+Communication+Strategy&rft.au=Quandt%2C+Sara+A%3BDoran%2C+Alicia+M%3BRao%2C+Pamela%3BHoppin%2C+Jane+A%3BSnively%2C+Beverly+M%3BArcury%2C+Thomas+A&rft.aulast=Quandt&rft.aufirst=Sara&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=636&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; MINORITIES; CHEMICAL CONTAMINATION CONTROL; INFORMATION, ENV; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Sensitivity of the Immature Rat Uterotrophic Assay to Mixtures of Estrogens AN - 14697918; 10660722 AB - The immature rat uterotrophic assay was used to evaluate the activity of mixtures of estrogens. Initially, various binary mixtures of bisphenol A and genistein, using doses that were individually active in the assay, were studied, and then a multicomponent mixture of seven estrogenic compounds was used, covering a range of anthropogenic, synthetic, and plant-derived estrogens. The seven compounds included: nonylphenol, bisphenol A, methoxychlor, genistein, estradiol, diethylstilbestrol, and ethinyl estradiol. Ethinyl estradiol was used as a positive control in most experiments. The mixture of bisphenol A and genistein gave intermediate uterine weights that were greater than the effect of bisphenol A alone but less than the effect of genistein alone. When the bisphenol A dose was fixed at 300 mg/kg with different doses of genistein, the genistein dose response was attenuated. In the complex mixture, doses of agents that gave a negative uterotrophic response when tested individually gave a positive response. The addition of individual uterotrophic responses for chemicals did not provide a useful estimate of the likely uterotrophic activity of the mixture. JF - Environmental Health Perspectives AU - Tinwell, Helen AU - Ashby, John Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 575 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHEMICAL CONTAMINATION, MULTIPLE KW - HORMONAL EFFECTS KW - HORMONES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14697918?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Sensitivity+of+the+Immature+Rat+Uterotrophic+Assay+to+Mixtures+of+Estrogens&rft.au=Tinwell%2C+Helen%3BAshby%2C+John&rft.aulast=Tinwell&rft.aufirst=Helen&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=575&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 22 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL CONTAMINATION, MULTIPLE; HORMONAL EFFECTS; HORMONES ER - TY - JOUR T1 - Phthalate Exposure and Pulmonary Function AN - 14696475; 10660721 AB - Urinary phthalate data from 289 participants in the Third National Health and Nutrition Examination Survey were used to assess phthalate exposure and pulmonary function. Linear regression analysis was used to evaluate the association. Monobutyl phthalate levels in urine were associated significantly with decrements in pulmonary function in males but not in females. Monoethyl phthalate concentration was associated inversely with forced vital capacity and forced expiratory volume at 1 s among males. For men who had never smoked, monobutyl phthalate was associated significantly with decreased forced vital capacity, and among women who had never smoked, monoethylhexyl phthalate was associated positively with forced expiratory volume at 1 s and maximum mid-expiratory flow. JF - Environmental Health Perspectives AU - Hoppin, Jane A AU - Ulmer, Ross AU - London, Stephanie J Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 571 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - PHTHALIC ACID ESTERS KW - PULMONARY EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14696475?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Phthalate+Exposure+and+Pulmonary+Function&rft.au=Hoppin%2C+Jane+A%3BUlmer%2C+Ross%3BLondon%2C+Stephanie+J&rft.aulast=Hoppin&rft.aufirst=Jane&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=571&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; PHTHALIC ACID ESTERS; PULMONARY EFFECTS ER - TY - JOUR T1 - Molecular Evidence of an Interaction Between Prenatal Environmental Exposures and Birth Outcomes in a Multiethnic Population AN - 14696417; 10660730 AB - In a sample of nonsmoking African American and Dominican women residing in Washington Heights, Central Harlem, and the South Bronx, NY, birth outcomes were examined in relation to prenatal exposure to environmental tobacco smoke. Maternal blood samples were analyzed for cotinine as a biomarker of exposure, and benzo(a)pyrene (BaP)-DNA adducts were analyzed as a molecular dosimeter. Self-reported environmental tobacco smoke and plasma cotinine differed by ethnicity, with African Americans being significantly more likely to report exposure and to have a higher rate of detectable cotinine. Mean birth weight and head circumference were lower among African American than among Dominican infants. Linear regression revealed that environmental tobacco smoke exposure was associated with smaller head circumference, and cotinine was associated significantly with birth length. While BaP-DNA alone was not associated significantly with birth outcomes, the interaction effect of BaP-DNA and environmental tobacco smoke was significant on birth weight and head circumference. There was a 6.8% reduction of birth weight and a 2.9% reduction in head circumference in the environmental tobacco smoke-positive group with higher BaP-DNA adduct levels. JF - Environmental Health Perspectives AU - Perera, Frederica P AU - Rauh, Virginia AU - Whyatt, Robin M AU - Tsai, Wei-Yann AU - Bernert, John T AU - Tu, Yi-Hsuan AU - Andrews, Howard Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 626 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - REPRODUCTION, HUMAN KW - PREGNANCY KW - DNA KW - CIGARETTE SMOKE KW - BENZO-A-PYRENE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14696417?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Molecular+Evidence+of+an+Interaction+Between+Prenatal+Environmental+Exposures+and+Birth+Outcomes+in+a+Multiethnic+Population&rft.au=Perera%2C+Frederica+P%3BRauh%2C+Virginia%3BWhyatt%2C+Robin+M%3BTsai%2C+Wei-Yann%3BBernert%2C+John+T%3BTu%2C+Yi-Hsuan%3BAndrews%2C+Howard&rft.aulast=Perera&rft.aufirst=Frederica&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=626&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - REPRODUCTION, HUMAN; DNA; PREGNANCY; CIGARETTE SMOKE; BENZO-A-PYRENE ER - TY - JOUR T1 - Urban Air Pollution and Mortality in a Cohort of Norwegian Men AN - 14696383; 10660727 AB - In a cohort of Norwegian men aged 4049 yr living in Oslo, associations between residential air pollution levels and mortality were explored. The indicators of air pollution exposure considered were sulfur dioxide and nitrogen oxides. The study period ranged 197298. Home address NO sub(x) exposure estimated using a geographical information system was found to be associated with the risk of dying, and the effect was strongest for respiratory deaths other than lung cancer. Increased NO sub(x) exposure, however, was also associated with deaths from lung cancer and ischemic heart disease. During the study, yearly averages of SO sub(2) levels were reduced by a factor of seven, whereas NO sub(x) exhibited no clear down- or upward trends. JF - Environmental Health Perspectives AU - Nafstad, Per AU - Haheim, Lise Lund AU - Wisloff, Torbjorn AU - Gram, Frederick AU - Oftedal, Bente AU - Holme, Ingar AU - Hjermann, Ingvar Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 610 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SULFUR DIOXIDE KW - AIR POLLUTION EFFECTS KW - NORWAY KW - URBAN ATMOSPHERE KW - NITROGEN OXIDES KW - MORTALITY PATTERNS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14696383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Urban+Air+Pollution+and+Mortality+in+a+Cohort+of+Norwegian+Men&rft.au=Nafstad%2C+Per%3BHaheim%2C+Lise+Lund%3BWisloff%2C+Torbjorn%3BGram%2C+Frederick%3BOftedal%2C+Bente%3BHolme%2C+Ingar%3BHjermann%2C+Ingvar&rft.aulast=Nafstad&rft.aufirst=Per&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=610&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; AIR POLLUTION EFFECTS; NORWAY; NITROGEN OXIDES; MORTALITY PATTERNS; URBAN ATMOSPHERE; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Prenatal Lead Exposure, delta -Aminolevulinc Acid, and Schizophrenia AN - 14696335; 10660717 AB - Prospectively collected serum samples were used to assess the association between lead exposure in the second trimester of pregnancy and schizophrenia. The nested casecontrol study involved a birth cohort in which schizophrenia and related disorders had been diagnosed. delta -Aminolevulinc acid ( delta -ALA) was used as an indirect biologic marker of Pb exposure. In the serum from all 119 subjects, concentrations of delta -ALA ranged from nondetectable to 79.5 ng/ml. Subjects with delta -ALA levels greater than or equal to 9.05 ng/ml were categorized as Pb exposed. The odds ratio for schizophrenia associated with higher delta -ALA was 1.83, increasing to 2.4 when mother's age at delivery was included in the logistic regression model. JF - Environmental Health Perspectives AU - Opler, Mark GA AU - Brown, Alan S AU - Graziano, Joseph AU - Desai, Manisha AU - Zheng, Wei AU - Schaefer, Catherine AU - Factor-Litvak, Pamela Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 548 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - DISEASES AND DISORDERS KW - PREGNANCY KW - BLOOD LEAD LEVEL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14696335?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prenatal+Lead+Exposure%2C+delta+-Aminolevulinc+Acid%2C+and+Schizophrenia&rft.au=Opler%2C+Mark+GA%3BBrown%2C+Alan+S%3BGraziano%2C+Joseph%3BDesai%2C+Manisha%3BZheng%2C+Wei%3BSchaefer%2C+Catherine%3BFactor-Litvak%2C+Pamela&rft.aulast=Opler&rft.aufirst=Mark&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=548&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; DISEASES AND DISORDERS; BLOOD LEAD LEVEL; PREGNANCY ER - TY - JOUR T1 - Asbestos-Induced Peritoneal Mesothelioma in a Construction Worker AN - 14695279; 10660728 JF - Environmental Health Perspectives AU - Fonte, Rodolfo AU - Gambettino, Salvatore AU - Melazzini, Mario AU - Scelsi, Mario AU - Zanon, Claudio AU - Candura, Stefano M Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 616 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - CARCINOGENIC MECHANISMS KW - PATHOLOGY, HUMAN KW - ASBESTOS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695279?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Asbestos-Induced+Peritoneal+Mesothelioma+in+a+Construction+Worker&rft.au=Fonte%2C+Rodolfo%3BGambettino%2C+Salvatore%3BMelazzini%2C+Mario%3BScelsi%2C+Mario%3BZanon%2C+Claudio%3BCandura%2C+Stefano+M&rft.aulast=Fonte&rft.aufirst=Rodolfo&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=616&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t photos N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; CARCINOGENIC MECHANISMS; PATHOLOGY, HUMAN; ASBESTOS ER - TY - JOUR T1 - Personal Exposure Meets Risk Assessment: a Comparison of Measured and Modeled Exposures and Risks in an Urban Community AN - 14695248; 10660724 AB - Using ambient VOC data collected in South Baltimore, MD, estimates of ambient-air toxic concentrations made using EPA's Assessment System for Population Exposure Nationwide (ASPEN) model were evaluated. Indoor and personal exposure concentrations were also measured for 37 adult residents. The most-recent ambient modeling results from the ASPEN model for the 11 target VOCs were obtained from the EPA Office of Air Quality Planning and Standards. For each VOC, ratios were calculated for each individual measurement to the ASPEN model estimates corresponding to the individual's home census tract. Cancer and noncancer risks were assessed for each VOC using conventional approaches. Results showed that the most frequently detected VOCs in personal air were benzene, carbon tetrachloride, chloroform, ethylbenzene, methylene chloride, methyl tert-butyl ether (MTBE), styrene, tetrachloroethylene, toluene, and xylenes. Similar frequencies were found in the indoor samples, except for styrene. For most of the VOCs, personal exposures were greater than indoor concentrations, which were greater than outdoor concentrations. The ASPEN-estimated ambient concentrations were generally lower than personal and indoor air measurements, but for benzene, CCl sub(4), methylene chloride, MTBE, tetrachloroethylene, and trichloroethylene, central estimates from the ASPEN model and indoor concentrations were comparable. Chloroform, benzene, CCl sub(4), and tetrachloroethylene presented the highest median cancer risks. Cumulative risk and cancer incidence estimates were similar for personal and indoor VOC concentrations, but the ASPEN model and measured residential outdoor concentrations resulted in much lower cumulative risk estimates. JF - Environmental Health Perspectives AU - Payne-Sturges, Devon C AU - Burke, Thomas A AU - Breysse, Patrick AU - Diener-West, Marie AU - Buckley, Timothy J Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 589 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MATHEMATIC MODELS, AIR KW - CANCER RISK KW - MARYLAND KW - VOLATILE ORGANIC COMPOUNDS KW - URBAN ATMOSPHERE KW - AMBIENT AIR KW - RISK ASSESSMENT KW - AIR POLLUTION, INDOOR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Personal+Exposure+Meets+Risk+Assessment%3A+a+Comparison+of+Measured+and+Modeled+Exposures+and+Risks+in+an+Urban+Community&rft.au=Payne-Sturges%2C+Devon+C%3BBurke%2C+Thomas+A%3BBreysse%2C+Patrick%3BDiener-West%2C+Marie%3BBuckley%2C+Timothy+J&rft.aulast=Payne-Sturges&rft.aufirst=Devon&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=589&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; AMBIENT AIR; MATHEMATIC MODELS, AIR; CANCER RISK; MARYLAND; AIR POLLUTION, INDOOR; VOLATILE ORGANIC COMPOUNDS; URBAN ATMOSPHERE ER - TY - JOUR T1 - Effects of Organochlorine Contaminants on Thyroid Hormone Levels in Arctic Breeding Glaucous Gulls, Larus hyperboreus AN - 14695219; 10660714 AB - Breeding glaucous gulls Larus hyperboreus were collected at the south and southeast coasts of Bear Island in the western Barents Sea during spring 2001, and several biometric measurements were recorded. Blood samples were also collected and examined for organochlorine contaminants and concentrations of total and free triiodothyronine (T sub(3)) and thyroxine (T sub(4)). Significant negative associations were discerned between blood levels of selected organochlorines and circulating thyroid hormones and thyroid hormone ratios in male gulls, but not in females. Gulls breeding in a high-organochlorine-exposed colony had lower plasma levels of T sub(4) and T sub(4):T sub(3) ratios compared with a less-exposed colony. In males, hexachlorobenzene and oxychlordane appeared to have a particularly negative effect on the T sub(4):T sub(3) ratio and on the circulating levels of T sub(4). JF - Environmental Health Perspectives AU - Verreault, Jonathan AU - Skaare, Janneche Utne AU - Jenssen, Bjorn Munro AU - Gabrielsen, Geir Wing Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 532 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - REPRODUCTION, BIRD KW - HORMONAL EFFECTS KW - ARCTIC WILDLIFE KW - THYROID FUNCTION KW - ORGANOCHLORINE PESTICIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695219?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+Organochlorine+Contaminants+on+Thyroid+Hormone+Levels+in+Arctic+Breeding+Glaucous+Gulls%2C+Larus+hyperboreus&rft.au=Verreault%2C+Jonathan%3BSkaare%2C+Janneche+Utne%3BJenssen%2C+Bjorn+Munro%3BGabrielsen%2C+Geir+Wing&rft.aulast=Verreault&rft.aufirst=Jonathan&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=532&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - REPRODUCTION, BIRD; HORMONAL EFFECTS; ARCTIC WILDLIFE; THYROID FUNCTION; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Is the Association of Airborne Particles with Daily Deaths Confounded by Gaseous Air Pollutants? An Approach to Control by Matching AN - 14694785; 10660719 AB - Matching is a traditional approach to control for potential confounding in epidemiology, but the approach has not been applied to the question of confounding by gaseous pollutants in particulate air pollution studies. Here, the approach was applied to a multi-city study of particulate air pollution and daily deaths. Starting with a time-stratified control sampling where control days for an event were all of the other days of the same month of the same year, a subset was used that was also matched on concentration of a gaseous air pollutant. Results showed a significant association between airborne particles and the risk of death, which was seen after control, but matching, for season and level of gaseous copollutants. Mortality due to PM sub(10) was increased when matched on maximum hourly ozone levels and on 24-h average sulfur dioxide levels. JF - Environmental Health Perspectives AU - Schwartz, Joel Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 557 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SULFUR DIOXIDE KW - AIR POLLUTION EFFECTS KW - URBAN ATMOSPHERE KW - PARTICULATES KW - OZONE KW - MORTALITY PATTERNS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Is+the+Association+of+Airborne+Particles+with+Daily+Deaths+Confounded+by+Gaseous+Air+Pollutants%3F+An+Approach+to+Control+by+Matching&rft.au=Schwartz%2C+Joel&rft.aulast=Schwartz&rft.aufirst=Joel&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=557&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; AIR POLLUTION EFFECTS; MORTALITY PATTERNS; OZONE; PARTICULATES; URBAN ATMOSPHERE ER - TY - JOUR T1 - Screening for Estrogen and Androgen Receptor Activities in 200 Pesticides by in Vitro Reporter Gene Assays Using Chinese Hamster Ovary Cells AN - 14694761; 10660713 AB - An in vitro reporter gene assay using Chinese hamster ovary cells was used to screen 200 pesticides for estrogen and androgen receptor activities. The 200 pesticides, which included organochlorines, diphenyl ethers, organophosphorus, pyrethroids, carbamates, acid amides, triazines, ureas, and others, are tabulated, and the reporter gene assay protocol is described. Results showed that 47 pesticides induced estrogenic activity in the estrogen receptor alpha assay, while 33 pesticides increased the estrogen receptor beta -mediated transactivation gene response, 29 of which also had estrogenic activity via estrogen receptor alpha . Ten pesticides showed antiestrogenic properties. None of the pesticides showed androgenic transcriptional activity of more than 20%, while 66 pesticides exhibited antiandrogenic effects. Thirty-four pesticides exhibited dual activities as estrogen receptor agonists and androgen receptor antagonists. All results are tabulated. JF - Environmental Health Perspectives AU - Kojima, Hiroyuki AU - Katsura, Eiji AU - Takeuchi, Shinji AU - Niiyama, Kazuhito AU - Kobayashi, Kunihiko Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 524 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DATA, CHEMICAL KW - HORMONAL EFFECTS KW - BIOASSAY KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694761?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Screening+for+Estrogen+and+Androgen+Receptor+Activities+in+200+Pesticides+by+in+Vitro+Reporter+Gene+Assays+Using+Chinese+Hamster+Ovary+Cells&rft.au=Kojima%2C+Hiroyuki%3BKatsura%2C+Eiji%3BTakeuchi%2C+Shinji%3BNiiyama%2C+Kazuhito%3BKobayashi%2C+Kunihiko&rft.aulast=Kojima&rft.aufirst=Hiroyuki&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=524&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DATA, CHEMICAL; HORMONAL EFFECTS; BIOASSAY; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Ambient Endotoxin Concentrations in PM sub(10) from Southern California AN - 14694096; 10660723 AB - Ambient air samples were collected in a variety of communities in southern California with differing climate profiles, degrees of urbanization, and air pollution levels, and endotoxin concentrations in PM sub(10) were measured and compared. Rural agricultural sites had the lowest PM sub(10) concentrations but were mid-range in terms of endotoxin, while the desert and mountain locations had lower PM sub(10) but were toward the upper end on the monitored communities for endotoxin. While no obvious seasonal patterns for endotoxin concentration were detected, higher airborne concentrations were suggested in JuneSeptember. Strong correlations between PM sub(10) and endotoxin concentrations were found in June, November, and February. JF - Environmental Health Perspectives AU - Mueller-Anneling, Linda AU - Avol, Ed AU - Peters, John M AU - Thorne, Peter S Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 583 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BACTERIA KW - SPATIAL COMPARISONS KW - PARTICULATES KW - AMBIENT AIR KW - CALIFORNIA KW - SEASONAL COMPARISONS KW - BIOLOGICAL CONTAMINATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Ambient+Endotoxin+Concentrations+in+PM+sub%2810%29+from+Southern+California&rft.au=Mueller-Anneling%2C+Linda%3BAvol%2C+Ed%3BPeters%2C+John+M%3BThorne%2C+Peter+S&rft.aulast=Mueller-Anneling&rft.aufirst=Linda&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=583&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AMBIENT AIR; BACTERIA; CALIFORNIA; SEASONAL COMPARISONS; SPATIAL COMPARISONS; BIOLOGICAL CONTAMINATION; PARTICULATES ER - TY - JOUR T1 - Reproductive Effects of Occupational DDT Exposure Among Male Malaria Control Workers AN - 14694063; 10660716 AB - The reproductive history of 2033 male workers in the anti-malaria campaign of Mexico was examined to assess the reproductive effects of occupational DDT exposure. The workers reported all pregnancies they had fathered and provided specific information for each pregnancy: year of pregnancy, spontaneous abortions and stillbirths, newborn sex, and congenital malformations. A detailed occupational history was obtained to assess DDT exposure. Of the 9187 pregnancies evaluated, 8650 were live births and 118 were stillbirths, and of the pregnancies, 72.5% occurred after the father had been exposed occupationally to DDT. The most-common congenital malformations were in the nervous system and the osteomuscular system, and the greatest number of congenital malformations was observed in pregnancies occurring after the fathers' occupational exposure began. JF - Environmental Health Perspectives AU - Salazar-Garcia, Felix AU - Gallardo-Diaz, Esperanza AU - Ceron-Mireles, Prudencia AU - Loomis, Dana AU - Borja-Aburto, Victor H Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 542 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ABORTION KW - HEALTH SAFETY, OCCUPATIONAL KW - MEXICO KW - REPRODUCTION, HUMAN KW - DDT KW - BIRTH DEFECTS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694063?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Reproductive+Effects+of+Occupational+DDT+Exposure+Among+Male+Malaria+Control+Workers&rft.au=Salazar-Garcia%2C+Felix%3BGallardo-Diaz%2C+Esperanza%3BCeron-Mireles%2C+Prudencia%3BLoomis%2C+Dana%3BBorja-Aburto%2C+Victor+H&rft.aulast=Salazar-Garcia&rft.aufirst=Felix&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=542&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; ABORTION; MEXICO; DDT; REPRODUCTION, HUMAN; BIRTH DEFECTS, HUMAN ER - TY - JOUR T1 - Structural Changes in Gill DNA Reveal the Effects of Contaminants on Puget Sound Fish AN - 14693543; 10660711 AB - English sole Parophrys vetulus and sediment were collected from two locations in Puget Sound, WA, one contaminated and the other not, and Fourier-transform infrared spectroscopy was used to identify a broad array of subtle structural changes in gill DNA. Expression of cytochrome P4501A was used to assess exposure of the gill to a variety of contaminants that are aryl hydrocarbon receptor agonists. Sediment analysis revealed substantially higher concentrations of PAHs and PCBs at the lower Duwamish River site than at Quartermaster Harbor. All gills of fish from the Duwamish River site exhibited minor cellular changes of unknown etiology, while only about half of the gills from Quartermaster Harbor exhibited such changes. Strong cytochrome P4501A expression was evident in the gill lamellar epithelium and pillar cells of fish from the more-contaminated site, and there was also staining in the endothelium of vessels in the gill arches. Fourier-transform infrared spectroscopy of gill DNA from the two sites resulted in mean spectra exhibiting significant differences, and principal component analysis revealed a distinct clustering of the two groups. JF - Environmental Health Perspectives AU - Malins, Donald C AU - Stegeman, John J AU - Anderson, Jack W AU - Johnson, Paul M AU - Gold, Jordan AU - Anderson, Katie M Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 511 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 5 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - SEDIMENT KW - PUGET SOUND KW - SPATIAL COMPARISONS KW - POLYCYCLIC AROMATIC HYDROCARBON KW - FISH, SALTWATER KW - DNA KW - MUTAGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14693543?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Structural+Changes+in+Gill+DNA+Reveal+the+Effects+of+Contaminants+on+Puget+Sound+Fish&rft.au=Malins%2C+Donald+C%3BStegeman%2C+John+J%3BAnderson%2C+Jack+W%3BJohnson%2C+Paul+M%3BGold%2C+Jordan%3BAnderson%2C+Katie+M&rft.aulast=Malins&rft.aufirst=Donald&rft.date=2004-04-01&rft.volume=112&rft.issue=5&rft.spage=511&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; SEDIMENT; PUGET SOUND; FISH, SALTWATER; DNA; SPATIAL COMPARISONS; MUTAGENIC AGENTS; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Conservation analysis of small RNA genes in Escherichia coli AN - 20060107; 6418242 AB - Motivation: Small RNA (sRNA) genes in Escherichia coli have been in focus recently, as 44 out of 55 experimentally confirmed sRNA genes have been precisely located in the genome. The object of this study is to analyze quantitatively the conservation of these sRNA genes and compare it with the conservation of protein-encoding genes, function-unknown regions and tRNA genes. Results: The results show that within an evolutionary distance of 0.26, both sRNA genes and protein-encoding genes display a similar tendency in their degrees of conservation at the nucleotide level. In addition, the conservation of sRNA genes is much stronger than function-unknown regions, but much weaker than tRNA genes. Based on the conservation of studied sRNA genes, we also give clues to estimate the total number of sRNA genes in E.coli. JF - Bioinformatics AU - Zhang, Y AU - Zhang, Z AU - Ling, L AU - Shi, B AU - Chen, R AD - Bioinformatics Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China,, crs@sun5.ibp.ac.cn Y1 - 2004/03/22/ PY - 2004 DA - 2004 Mar 22 VL - 20 IS - 5 SN - 1367-4803, 1367-4803 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology; Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - Genomes KW - RNA KW - tRNA KW - Escherichia coli KW - Bioinformatics KW - Nucleotides KW - J 02310:Genetics & Taxonomy KW - N 14810:Methods KW - W 30965:Miscellaneous, Reviews KW - G 07770:Bacteria KW - W4 350:Bioinformatics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20060107?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioinformatics&rft.atitle=Conservation+analysis+of+small+RNA+genes+in+Escherichia+coli&rft.au=Zhang%2C+Y%3BZhang%2C+Z%3BLing%2C+L%3BShi%2C+B%3BChen%2C+R&rft.aulast=Zhang&rft.aufirst=Y&rft.date=2004-03-22&rft.volume=20&rft.issue=5&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Bioinformatics&rft.issn=13674803&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-03-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Genomes; RNA; tRNA; Bioinformatics; Nucleotides; Escherichia coli ER - TY - JOUR T1 - Evaluation of non-destructive methods of measuring growth stress in Eucalyptus globulus: relationships between strain, wood properties and stress AN - 17985259; 5932307 AB - High levels of growth stress are implicated in causing end splitting of logs, deflection during sawing and deformation of boards as stresses are released during sawing operations. Level of stress is a function of strain and the elastic modulus of the wood (MOE). Levels of peripheral strain can be measured on standing trees and, if the MOE is known, stresses can be estimated. The validity of using peripheral strain measurements relies on underlying theoretical models that relate strain to expected patterns of stress distribution and levels of board deflection. This study evaluates these theoretical relationships by determining relationships of stress and strain with board deflection, end splitting and a range of wood properties. Peripheral strain levels were extremely variable within the bottom log and little evidence was found for consistent patterns of variation, although measurements generally increased with increasing height above ground. Sampling on two sides of the standing tree at breast height appeared to be a suitable strategy, with the mean for these strain readings having a correlation (r) of 0.86 with the average strain in the bottom log. Growth strain was not a reliable predictor of board deflection and cannot be recommended as a non-destructive sampling method. Overall there was a poor relationship between growth strain and board deflection. No consistent relationships were found between a range of wood properties and growth strain or board deflection across both sites. Stress levels were calculated for each tree as the product of growth strain and modulus of elasticity and the relationship between calculated stress and mean board deflection determined. No relationship was found at either site with correlations being very close to zero. The underlying theoretical relationships between stress and strain were examined and several questions raised about the validity of such models. JF - Forest Ecology and Management AU - Raymond, CA AU - Kube, P D AU - Pinkard, L AU - Savage, L AU - Bradley, AD AD - Cooperative Research Centre for Sustainable Production Forestry, GPO Box 252-12, Hobart, Tasmania 7001, Australia, carolynr@sf.nsw.gov.au Y1 - 2004/03/22/ PY - 2004 DA - 2004 Mar 22 SP - 187 EP - 200 VL - 190 IS - 2-3 SN - 0378-1127, 0378-1127 KW - Bluegum eucalyptus KW - Ecology Abstracts KW - Forest management KW - Trees KW - Stress KW - Sampling KW - Eucalyptus globulus KW - Models KW - Methodology KW - D 04001:Methodology - general UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17985259?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forest+Ecology+and+Management&rft.atitle=Evaluation+of+non-destructive+methods+of+measuring+growth+stress+in+Eucalyptus+globulus%3A+relationships+between+strain%2C+wood+properties+and+stress&rft.au=Raymond%2C+CA%3BKube%2C+P+D%3BPinkard%2C+L%3BSavage%2C+L%3BBradley%2C+AD&rft.aulast=Raymond&rft.aufirst=CA&rft.date=2004-03-22&rft.volume=190&rft.issue=2-3&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Forest+Ecology+and+Management&rft.issn=03781127&rft_id=info:doi/10.1016%2Fj.foreco.2003.10.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eucalyptus globulus; Stress; Methodology; Trees; Sampling; Models; Forest management DO - http://dx.doi.org/10.1016/j.foreco.2003.10.011 ER - TY - BOOK T1 - Report on the meeting of experts on digital preservation, U.S. Government Printing Office, Washington, D.C., March 12, 2004 AN - 59940564; 2004-1002090 AB - Discusses standards and specifications for the creation of digital objects for preservation, and minimum requirements for a project to digitize US government documents held in depositories. JF - United States Government Printing Office, March 12 2004. Y1 - 2004/03/12/ PY - 2004 DA - 2004 Mar 12 PB - United States Government Printing Office KW - Government publications -- Conservation and restoration KW - Digital media -- Standardization KW - Digital preservation -- United States KW - Government records -- Conservation and restoration KW - Digital libraries -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59940564?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-03-12&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Report+on+the+meeting+of+experts+on+digital+preservation%2C+U.S.+Government+Printing+Office%2C+Washington%2C+D.C.%2C+March+12%2C+2004&rft.title=Report+on+the+meeting+of+experts+on+digital+preservation%2C+U.S.+Government+Printing+Office%2C+Washington%2C+D.C.%2C+March+12%2C+2004&rft.issn=&rft_id=info:doi/ L2 - http://www.gpoaccess.gov/about/reports/preservation.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Govt Printing Office N1 - Document feature - bibl(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - GEN T1 - Missile Survey: Ballistic and Cruise Missiles of Foreign Countries [Includes Maps and Tables] AN - 1679114334; WM00601 AB - Summarizes intelligence on foreign missile programs and assesses the threat posed by these to the U.S. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2004 SP - 42 KW - Ballistic missiles KW - China KW - Cruise missiles KW - India KW - Iran KW - Iraq KW - Korea (North) KW - Missile flight tests KW - Missile proliferation KW - Pakistan KW - Russia KW - Threat analysis KW - Unmanned aerial vehicles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679114334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_wm&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Missile+Survey%3A+Ballistic+and+Cruise+Missiles+of+Foreign+Countries+%5BIncludes+Maps+and+Tables%5D&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2004-03-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Analyte descriptor - NSA document type: Report N1 - Last updated - 2015-06-16 ER - TY - GEN T1 - Latex allergy. AN - 71824313; 15074518 JF - AORN journal AU - Arthur, Terri AU - Bellistri, Mary AU - Butler, Janet AU - D'Intinosanto, Michael AU - Homer, Janice AU - Lenehan, Gail AU - O'Connor, Elizabeth AU - Bain, Evelyn AU - Massachusetts Nurses Association Congress on Health and Safety Y1 - 2004/03// PY - 2004 DA - March 2004 SP - 579 EP - 80; author reply 582-4; discussion 584-5 VL - 79 IS - 3 KW - Latex KW - 0 KW - Index Medicus KW - Nursing KW - United States KW - Humans KW - Latex -- adverse effects KW - Latex Hypersensitivity -- prevention & control KW - Gloves, Surgical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71824313?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=AORN+journal&rft.atitle=Latex+allergy.&rft.au=Arthur%2C+Terri%3BBellistri%2C+Mary%3BButler%2C+Janet%3BD%27Intinosanto%2C+Michael%3BHomer%2C+Janice%3BLenehan%2C+Gail%3BO%27Connor%2C+Elizabeth%3BBain%2C+Evelyn%3BMassachusetts+Nurses+Association+Congress+on+Health+and+Safety&rft.aulast=Arthur&rft.aufirst=Terri&rft.date=2004-03-01&rft.volume=79&rft.issue=3&rft.spage=579&rft.isbn=&rft.btitle=&rft.title=AORN+journal&rft.issn=00012092&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-25 N1 - Date created - 2004-04-12 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment On: AORN J. 2003 Oct;78(4):595-8, 601-3 [14575184] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Targeting HIV-related outcomes with intravenous drug users maintained on methadone: a randomized clinical trial of a harm reduction group therapy. AN - 71790765; 15050083 AB - Methadone maintenance programs (MMP) have the potential to play an important role in reducing HIV risk, given the appropriate type and level of ancillary treatments. In this study, we investigated the efficacy of a 12-session harm reduction group intervention for injection drug users, based upon the Information-Motivation-Behavioral skills model of behavior change, that focused on reducing both drug and sex risk. Two hundred and twenty patients entering an MMP were randomized to receive either standard care (SC)-2 hours of counseling per month and a single-session risk reduction intervention-or SC plus the harm reduction group (HRG). Results showed that during treatment, patients receiving HRG were more likely to be abstinent from cocaine and to report fewer unsafe sexual practices. Post-treatment, HRG patients scored higher on a sexual risk quiz and reported increased self-efficacy in high risk sexual situations. Enhancing methadone maintenance with a weekly harm reduction group treatment was somewhat more expensive but can bring about positive changes in behaviors and attitudes that are associated with the transmission of HIV. JF - Journal of substance abuse treatment AU - Avants, S Kelly AU - Margolin, Arthur AU - Usubiaga, Mary Helen AU - Doebrick, Cheryl AD - Yale University School of Medicine, Department of Psychiatry, Welch Building, 495 Congress Avenue, New Haven, CT 06519, USA. Y1 - 2004/03// PY - 2004 DA - March 2004 SP - 67 EP - 78 VL - 26 IS - 2 SN - 0740-5472, 0740-5472 KW - Analgesics, Opioid KW - 0 KW - Methadone KW - UC6VBE7V1Z KW - Index Medicus KW - Harm Reduction KW - Costs and Cost Analysis KW - Risk-Taking KW - Motivation KW - Humans KW - Cocaine-Related Disorders -- complications KW - Condoms KW - Sexual Behavior KW - Behavior Therapy KW - Needle Sharing KW - Adult KW - Treatment Outcome KW - Heroin Dependence -- complications KW - Female KW - Male KW - Methadone -- adverse effects KW - Methadone -- therapeutic use KW - HIV Infections -- complications KW - Substance Abuse, Intravenous -- rehabilitation KW - HIV Infections -- drug therapy KW - Analgesics, Opioid -- therapeutic use KW - Analgesics, Opioid -- adverse effects KW - Substance Abuse, Intravenous -- complications KW - HIV Infections -- psychology KW - Substance Abuse, Intravenous -- psychology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71790765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+substance+abuse+treatment&rft.atitle=Targeting+HIV-related+outcomes+with+intravenous+drug+users+maintained+on+methadone%3A+a+randomized+clinical+trial+of+a+harm+reduction+group+therapy.&rft.au=Avants%2C+S+Kelly%3BMargolin%2C+Arthur%3BUsubiaga%2C+Mary+Helen%3BDoebrick%2C+Cheryl&rft.aulast=Avants&rft.aufirst=S&rft.date=2004-03-01&rft.volume=26&rft.issue=2&rft.spage=67&rft.isbn=&rft.btitle=&rft.title=Journal+of+substance+abuse+treatment&rft.issn=07405472&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-07-21 N1 - Date created - 2004-03-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Differential involvement of N-type calcium channels in transmitter release from vasoconstrictor and vasodilator neurons. AN - 71728669; 14993106 AB - 1. The effects of calcium channel blockers on co-transmission from different populations of autonomic vasomotor neurons were studied on isolated segments of uterine artery and vena cava from guinea-pigs. 2. Sympathetic, noradrenergic contractions of the uterine artery (produced by 200 pulses at 1 or 10 Hz; 600 pulses at 20 Hz) were abolished by the N-type calcium channel blocker omega-conotoxin (CTX) GVIA at 1-10 nm. 3. Biphasic sympathetic contractions of the vena cava (600 pulses at 20 Hz) mediated by noradrenaline and neuropeptide Y were abolished by 10 nm CTX GVIA. 4. Neurogenic relaxations of the uterine artery (200 pulses at 10 Hz) mediated by neuronal nitric oxide and neuropeptides were reduced <50% by CTX GVIA 10-100 nm. 5. Capsaicin (3 microm) did not affect the CTX GVIA-sensitive or CTX GVIA-resistant neurogenic relaxations of the uterine artery. 6. The novel N-type blocker CTX CVID (100-300 nm), P/Q-type blockers agatoxin IVA (10-100 nm) or CTX CVIB (100 nm), the L-type blocker nifedipine (10 microm) or the 'R-type' blocker SNX-482 (100 nm), all failed to reduce CTX GVIA-resistant relaxations. The T-type channel blocker NiCl(2) (100-300 microm) reduced but did not abolish the remaining neurogenic dilations. 7. Release of different neurotransmitters from the same autonomic vasomotor axon depends on similar subtypes of calcium channels. N-type channels are responsible for transmitter release from vasoconstrictor neurons innervating a muscular artery and capacitance vein, but only partly mediate release of nitric oxide and neuropeptides from pelvic vasodilator neurons. JF - British journal of pharmacology AU - Morris, Judy L AU - Ozols, Daina I AU - Lewis, Richard J AU - Gibbins, Ian L AU - Jobling, Phillip AD - Department of Anatomy & Histology, Centre for Neuroscience, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia. Judy.Morris@flinders.edu.au Y1 - 2004/03// PY - 2004 DA - March 2004 SP - 961 EP - 970 VL - 141 IS - 6 SN - 0007-1188, 0007-1188 KW - Calcium Channel Blockers KW - 0 KW - Calcium Channels, N-Type KW - Neurotransmitter Agents KW - omega-Conotoxins KW - Index Medicus KW - Uterus -- innervation KW - Vena Cava, Inferior -- innervation KW - Animals KW - Neurotransmitter Agents -- metabolism KW - Guinea Pigs KW - In Vitro Techniques KW - Vasodilation -- drug effects KW - Vasoconstriction -- drug effects KW - Uterus -- blood supply KW - Muscle, Smooth, Vascular -- innervation KW - Female KW - Motor Neurons -- physiology KW - Calcium Channel Blockers -- pharmacology KW - Calcium Channels, N-Type -- physiology KW - Calcium Channels, N-Type -- drug effects KW - Synaptic Transmission -- drug effects KW - omega-Conotoxins -- pharmacology KW - Motor Neurons -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71728669?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=British+journal+of+pharmacology&rft.atitle=Differential+involvement+of+N-type+calcium+channels+in+transmitter+release+from+vasoconstrictor+and+vasodilator+neurons.&rft.au=Morris%2C+Judy+L%3BOzols%2C+Daina+I%3BLewis%2C+Richard+J%3BGibbins%2C+Ian+L%3BJobling%2C+Phillip&rft.aulast=Morris&rft.aufirst=Judy&rft.date=2004-03-01&rft.volume=141&rft.issue=6&rft.spage=961&rft.isbn=&rft.btitle=&rft.title=British+journal+of+pharmacology&rft.issn=00071188&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-04-11 N1 - Date created - 2004-03-18 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Pain. 2002 Mar;96(1-2):119-27 [11932068] Jpn J Pharmacol. 2001 Nov;87(3):208-13 [11885970] Eur J Pharmacol. 2002 Sep 20;451(3):279-86 [12242089] Br J Pharmacol. 2002 Nov;137(6):805-12 [12411411] Am J Physiol Heart Circ Physiol. 2002 Dec;283(6):H2627-35 [12388237] Physiol Rev. 2003 Jan;83(1):117-61 [12506128] J Biol Chem. 2003 Feb 7;278(6):4057-62 [12441339] Prog Brain Res. 1986;68:241-62 [2882554] J Physiol. 1987 Dec;394:149-72 [2451016] Eur J Pharmacol. 1989 Mar 21;162(2):375-9 [2542061] Regul Pept. 1991 Feb 26;32(3):297-310 [1678196] Neuron. 1992 Jan;8(1):3-11 [1370373] Nature. 1992 Feb 27;355(6363):827-9 [1311418] Rev Physiol Biochem Pharmacol. 1992;121:49-146 [1485073] J Auton Nerv Syst. 1993 Jan;42(1):11-21 [8094724] Nature. 1993 Mar 25;362(6418):318-24 [8455717] Br J Pharmacol. 1994 Apr;111(4):1321-7 [7913375] J Physiol. 1995 Dec 1;489 ( Pt 2):363-75 [8847632] J Neurosci. 1996 Jul 1;16(13):4155-61 [8753877] Neuroscience. 1996 Feb;70(3):817-24 [9045091] Br J Pharmacol. 1997 Feb;120(3):393-8 [9031741] Gen Pharmacol. 1997 Mar;28(3):393-7 [9068979] J Physiol. 1997 Mar 1;499 ( Pt 2):341-9 [9080364] Neuroreport. 1997 Sep 29;8(14):3023-8 [9331909] Br J Pharmacol. 1998 Jan;123(2):167-72 [9489603] J Bioenerg Biomembr. 1998 Aug;30(4):335-45 [9758330] Biochemistry. 1998 Nov 3;37(44):15353-62 [9799496] J Auton Nerv Syst. 1998 Nov 10;73(2-3):115-24 [9862386] Br J Pharmacol. 1999 Jan;126(1):11-8 [10051115] Neuroscience. 1999;94(3):891-6 [10579580] Br J Pharmacol. 1999 Dec;128(7):1602-8 [10602342] Free Radic Res. 1999 Dec;31(6):577-96 [10630682] Prog Neurobiol. 2000 Feb;60(2):181-210 [10639054] Br J Pharmacol. 2000 Jan;129(1):47-52 [10694201] Pharmacol Toxicol. 2000 Jan;86(1):30-5 [10720104] Regul Pept. 2000 Sep 25;93(1-3):93-107 [11033057] J Biol Chem. 2000 Nov 10;275(45):35335-44 [10938268] Br J Pharmacol. 2000 Dec;131(7):1325-36 [11090104] Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5323-8 [11296258] Am J Physiol Heart Circ Physiol. 2001 Nov;281(5):H2124-32 [11668074] J Neurophysiol. 2002 Jun;87(6):2844-50 [12037187] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Concentrations of organochlorines in sperm whales (Physeter macrocephalus) from Southern Australian waters. AN - 71673357; 14980465 AB - Concentrations of DDTs, PCBs and HCHs were measured in sperm whales involved in two mass stranding events on the west coast of Tasmania, Australia in February 1998. DDTs and PCBs were present in all samples analysed, while only three contained HCHs. The relationships between organochlorines, sex, age and reproductive groups were marked by high variability. Differences in organochlorine concentrations were observed between animals from the two stranding sites and discussed in light of the ecology of this species. Concentrations of all pollutants were stratified throughout the vertical aspect of the blubber and possible reasons for and the implications of this are discussed. Concentrations of compounds were higher than those documented in this species in the Southern Hemisphere previously, although were relatively lower than those documented in the Northern Hemisphere. However, comparisons were confounded by spatial and temporal differences. Continued monitoring of marine mammals throughout this region in a co-coordinated, standardized manner is essential for establishing definite temporal and spatial variations in pollutant concentrations. JF - Marine pollution bulletin AU - Evans, Karen AU - Hindell, Mark AU - Hince, Greg AD - Antarctic Wildlife Research Unit, School of Zoology, University of Tasmania, GPO Box 252-05, Hobart, Tasmania 7001, Australia. karen.evans@csiro.au Y1 - 2004/03// PY - 2004 DA - March 2004 SP - 486 EP - 503 VL - 48 IS - 5-6 SN - 0025-326X, 0025-326X KW - Hydrocarbons, Chlorinated KW - 0 KW - Insecticides KW - Index Medicus KW - Environmental Monitoring KW - Mortality KW - Animals KW - Australia KW - Tissue Distribution KW - Adipose Tissue -- chemistry KW - Insecticides -- pharmacokinetics KW - Insecticides -- analysis KW - Whales UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71673357?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+pollution+bulletin&rft.atitle=Concentrations+of+organochlorines+in+sperm+whales+%28Physeter+macrocephalus%29+from+Southern+Australian+waters.&rft.au=Evans%2C+Karen%3BHindell%2C+Mark%3BHince%2C+Greg&rft.aulast=Evans&rft.aufirst=Karen&rft.date=2004-03-01&rft.volume=48&rft.issue=5-6&rft.spage=486&rft.isbn=&rft.btitle=&rft.title=Marine+pollution+bulletin&rft.issn=0025326X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-15 N1 - Date created - 2004-02-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Cannabis in Papua New Guinea. AN - 67307707; 18181450 AB - This review covers published information on psychoactive drugs, particularly cannabis, in Papua New Guinea. Legal drugs are mentioned to place the illegal drugs into a broader public health context. Although a number of psychoactive drugs were used traditionally (and are used now), cannabis is the only illicit drug for which prevalence of use is currently not negligible. Very little epidemiology research on cannabis use and its individual and public health sequelae has been conducted, although a fuller criminology literature on the topic exists. The published cannabis use prevalence studies are limited in scope, and the most-cited one is of questionable accuracy. The complex interactions between the health of individuals and their social environments are highlighted by the destructive impacts that cannabis cultivation, trafficking and use are having in contemporary PNG. JF - Pacific health dialog AU - McDonald, David AD - National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia. David.McDonald@gpo.com.au Y1 - 2004/03// PY - 2004 DA - March 2004 SP - 96 EP - 101 VL - 11 IS - 1 SN - 1015-7867, 1015-7867 KW - Cannabinoids KW - 0 KW - Street Drugs KW - Index Medicus KW - Phytotherapy KW - Drug and Narcotic Control KW - Humans KW - Street Drugs -- adverse effects KW - Street Drugs -- legislation & jurisprudence KW - Cannabis -- adverse effects KW - Papua New Guinea -- epidemiology KW - Prevalence KW - Medicine, Traditional KW - Cannabinoids -- economics KW - Cannabinoids -- adverse effects KW - Marijuana Abuse -- economics KW - Marijuana Abuse -- epidemiology KW - Cannabinoids -- therapeutic use KW - Marijuana Abuse -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67307707?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pacific+health+dialog&rft.atitle=Cannabis+in+Papua+New+Guinea.&rft.au=McDonald%2C+David&rft.aulast=McDonald&rft.aufirst=David&rft.date=2004-03-01&rft.volume=11&rft.issue=1&rft.spage=96&rft.isbn=&rft.btitle=&rft.title=Pacific+health+dialog&rft.issn=10157867&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-19 N1 - Date created - 2008-01-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Can We Be a Democracy if Democracy Ends at the Workplace Door? AN - 60492083; 200414474 AB - Noting the small percentage of unionized American workers in contemporary American society, it is suggested that national democratic practices are diminished when democracy is disassociated from the workplace. Movements initiated by workers at certain corporations & by graduate students at several prestigious American universities are cited to illustrate that union organizing is needed in many sectors. Several rhetorical questions that identify problematic aspects of union elections in the US are asked to illuminate the nondemocratic nature of such elections; in addition, a comparison of US labor unions' & the International Labor Organizations' understanding of human rights in the workplace is performed to show deficiencies within American unions. Moreover, data from 20th-century presidential elections, especially the 2000 election is scrutinized, revealing a correlation between the decline in election participation & union membership. Initiatives created by labor union organizations designed to inform the American public about US labor unions are also discussed. Adapted from the source document. JF - New Political Science AU - Sweeney, John J AD - American Federation Labor, Congress Industrial Organizations Y1 - 2004/03// PY - 2004 DA - March 2004 SP - 99 EP - 104 VL - 26 IS - 1 SN - 0739-3148, 0739-3148 KW - Labor Policy KW - Unions KW - United States of America KW - Democracy KW - Labor Movements KW - article KW - 0621: complex organization; jobs, work organization, workplaces, & unions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60492083?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=New+Political+Science&rft.atitle=Can+We+Be+a+Democracy+if+Democracy+Ends+at+the+Workplace+Door%3F&rft.au=Sweeney%2C+John+J&rft.aulast=Sweeney&rft.aufirst=John&rft.date=2004-03-01&rft.volume=26&rft.issue=1&rft.spage=99&rft.isbn=&rft.btitle=&rft.title=New+Political+Science&rft.issn=07393148&rft_id=info:doi/10.1080%2F0739314042000185148 LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - NPSCD9 N1 - SubjectsTermNotLitGenreText - Unions; Labor Policy; Democracy; Labor Movements; United States of America DO - http://dx.doi.org/10.1080/0739314042000185148 ER - TY - JOUR T1 - Prediction of short-range maximum NO sub(2) concentrations using scalar PDFS AN - 28349033; 200405-31-0771 (CE); 05827556 (EN) AB - Significant emissions of NO sub(x) (oxides of nitrogen: NO and NO sub(2)) are common from sources such as power stations, road tunnel ventilation outputs and freeways. As these species are chemically reactive (NO+O sub(3)[rightwards arrow]O sub(2)+NO sub(2)), their concentrations downwind from the source are influenced by both the atmospheric turbulence (dispersion) and the chemical reactions. As part of an ongoing research project to investigate the effects of mixing on chemical reactions in the atmosphere, we make use of a new modelling technique based on the concentration statistics of a non-reactive (conserved) scalar. A simplified form of the model is an upper (conservative) limit on toxic NO sub(2) concentrations. The novelty of this limit is that it is less conservative than previous methods commonly in use by air quality modellers but has a sound physical basis and can readily be calculated for atmospheric plumes. Model results are presented for NO, O sub(3) and NO sub(2). When model predictions for NO sub(2) are compared to atmospheric field data it is found that the model limit is a conservative bound on their concentrations. The present model is restricted to the plume centreline. The two main inputs are a parameterisation for the concentration fluctuations (conditional dissipation of scalar concentration fluctuations) and the probability density function (pdf) of the conserved scalar in the plume. Careful choices of these inputs are necessary for correct model behaviour and to ensure internal model consistency. Future work needed to improve present model limitations is described including: use of the pdf transport equation; ways to remove the need for model parameters by appeal to basic physics, and generalisation of the present centreline restriction. JF - Atmospheric Environment AU - Brown, R J AU - Woodfield, P L AD - School of Mechanical, Manufacturing and Medical Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, Qld 4001, Australia richard.brown@qut.edu.au PY - 2004 SP - 1379 EP - 1386 PB - Elsevier Science BV, P.O. Box 211, Amsterdam, 1000 AE, Netherlands, [mailto:w.tukker@elsevier.nl], [URL:http://www.elsevier.com] VL - 38 IS - 9 SN - 1352-2310, 1352-2310 KW - Civil Engineering (CE); Environmental Engineering (EN) KW - Mathematical models KW - Reactions (chemical) KW - Fluctuation KW - Turbulent flow KW - Statistics KW - Roads KW - Air quality KW - Atmospheres KW - Turbulence KW - Power stations KW - Computational fluid dynamics KW - Tunnels (transportation) KW - Emission KW - Density KW - Mixing KW - Dissipation KW - Freeways KW - Ventilation KW - Fluid flow KW - Article KW - EE 20:Air Pollution: Monitoring, Control & Remediation (EN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/28349033?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Prediction+of+short-range+maximum+NO+sub%282%29+concentrations+using+scalar+PDFS&rft.au=Brown%2C+R+J%3BWoodfield%2C+P+L&rft.aulast=Brown&rft.aufirst=R&rft.date=2004-03-01&rft.volume=38&rft.issue=9&rft.spage=1379&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2003.10.058 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-11-11 DO - http://dx.doi.org/10.1016/j.atmosenv.2003.10.058 ER - TY - JOUR T1 - Optimisation technique for calculating water transport in a box model (Gippsland Lakes, Victoria, Australia) AN - 20986757; 5932121 AB - A new variational approach to calculating water transport in a box model by inverse salinity modelling is presented. It allows one to calculate water transport robustly in cases when traditional salt-balance techniques fail. Application of the developed technique to a box model of Gippsland Lakes estuary, Victoria, Australia, is described. JF - Estuarine, Coastal and Shelf Science AU - Sakov, P AU - Parslow, J S AD - CSIRO Marine Research, GPO 1538, Hobart, Tasmania 7001, Australia, Pavel.Sakov@csiro.au Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 417 EP - 428 PB - Elsevier Ltd VL - 59 IS - 3 SN - 0272-7714, 0272-7714 KW - Aqualine Abstracts; Oceanic Abstracts; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Estuarine dynamics KW - Water Transport KW - Mathematical models KW - Salt transport KW - PSE, Australia, Victoria, Gippsland, Gippsland Lakes KW - Estuaries KW - Estuarine salinity KW - Model Studies KW - Lakes KW - Salinity KW - Transport processes KW - Estuarine models KW - Australia, Victoria, Gippsland, Lakes Entrance KW - Modelling KW - AQ 00001:Water Resources and Supplies KW - SW 0850:Lakes KW - M2 556:General (556) KW - O 2090:Instruments/Methods KW - Q2 09162:Methods and instruments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20986757?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Optimisation+technique+for+calculating+water+transport+in+a+box+model+%28Gippsland+Lakes%2C+Victoria%2C+Australia%29&rft.au=Sakov%2C+P%3BParslow%2C+J+S&rft.aulast=Sakov&rft.aufirst=P&rft.date=2004-03-01&rft.volume=59&rft.issue=3&rft.spage=417&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2003.10.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Estuarine dynamics; Salinity; Mathematical models; Transport processes; Modelling; Salt transport; Estuarine salinity; Estuarine models; Lakes; Water Transport; Estuaries; Model Studies; PSE, Australia, Victoria, Gippsland, Gippsland Lakes; Australia, Victoria, Gippsland, Lakes Entrance DO - http://dx.doi.org/10.1016/j.ecss.2003.10.002 ER - TY - JOUR T1 - Multiple paternity in field- and captive-laid egg strands of Sepioteuthis australis (Cephalopoda : Loliginidae) AN - 20922278; 6127010 AB - Previous observations on the mating behaviour of the southern calamary, Sepioteuthis australis Quoy & Gaimard 1833, revealed the potential for multiple paternities within egg strands, which contained up to eight eggs each. Six egg masses were laid in captivity from a possible 14 female and 20 male parents. By using five microsatellite loci, 112 eggs from 35 randomly selected egg strands were assigned sires using the potential fathers' genotypes. Seven egg strands containing 22 eggs were also collected from the field to test that squid in captivity were apportioning eggs in natural ways, and that multiple paternity within egg strands was not an artefact of captivity. Ninety-seven per cent of strands laid in captivity showed multiple paternities. Similarly, multiple fathers were also evident in the field-laid egg strands. The maximum number of sires found within a single egg strand was four; however, three sires were more common. This is the first account of multiple paternities within egg strands laid by Sepioteuthis. It is likely that females are 'spermatophore-limited' when egg laying, and are promiscuous to ensure a ready supply of these sperm packets. Moreover, genetic diversity in a brood is increased by this mating strategy. JF - Marine & Freshwater Research AU - van Camp, LM AU - Donnellan, S C AU - Dyer, A R AU - Fairweather, P G AD - School of Biological Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia, lissa.vancamp@halliburton.com Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 819 EP - 823 VL - 55 IS - 8 SN - 1323-1650, 1323-1650 KW - Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Marine KW - Loliginidae KW - Nucleotide sequence KW - Paternity KW - Microsatellites KW - Cephalopoda KW - Genetic diversity KW - Sperm KW - Genotypes KW - Freshwater KW - Sepioteuthis KW - Artefacts KW - Eggs KW - Egg laying KW - Sepioteuthis australis KW - DNA KW - Marine molluscs KW - Reproductive behaviour KW - Captivity KW - O 1070:Ecology/Community Studies KW - D 04658:Molluscs KW - Q1 08423:Behaviour UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20922278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+%26+Freshwater+Research&rft.atitle=Multiple+paternity+in+field-+and+captive-laid+egg+strands+of+Sepioteuthis+australis+%28Cephalopoda+%3A+Loliginidae%29&rft.au=van+Camp%2C+LM%3BDonnellan%2C+S+C%3BDyer%2C+A+R%3BFairweather%2C+P+G&rft.aulast=van+Camp&rft.aufirst=LM&rft.date=2004-03-01&rft.volume=55&rft.issue=8&rft.spage=819&rft.isbn=&rft.btitle=&rft.title=Marine+%26+Freshwater+Research&rft.issn=13231650&rft_id=info:doi/10.1071%2FMF03179 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-10-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Nucleotide sequence; DNA; Genetic diversity; Marine molluscs; Genotypes; Reproductive behaviour; Eggs; Captivity; Egg laying; Paternity; Microsatellites; Sperm; Artefacts; Loliginidae; Sepioteuthis australis; Cephalopoda; Sepioteuthis; Marine; Freshwater DO - http://dx.doi.org/10.1071/MF03179 ER - TY - JOUR T1 - MEF up-regulates human beta -defensin 2 expression in epithelial cells AN - 20484188; 7492050 AB - Human beta -defensin 2 (HBD2), an antimicrobial peptide, is widely expressed in epithelial tissues and displays a potent killing activity in response to the invasiveness of a wide range of microorganisms and the stimulation of various molecules. Myeloid ELF-1-like factor (MEF) has been reported to be involved in innate immunity responses, such as activation of perforin and lysozyme transcription. The role of MEF in the transcription regulation of HBD2, however, is unknown. Here, we show that MEF not only activated HBD2 promoter activity, but also increased the endogenous HBD2 transcription level. Moreover, the activated HBD2 promoter activity was attenuated by the antisense MEF RNA input and the loss of the ETS binding site (EBS: GGAA core sequence) in the HBD2 promoter. The interaction between the EBS and MEF protein was further confirmed by electrophoretic mobility shift assay. Thus, our data indicate that MEF may play an important role in regulating HBD2 expression in epithelial cells. JF - FEBS Letters AU - Lu, Zhuo AU - Kim, Kyoung-Ah AU - Suico, Mary Ann AU - Shuto, Tsuyoshi AU - Li, Jian-Dong AU - Kai, Hirofumi AD - Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan, hirokai@gpo.kumamoto-u.ac.jp Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 117 EP - 121 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 561 IS - 1-3 SN - 0014-5793, 0014-5793 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Immunology Abstracts KW - Author Keywords: Myeloid ELF-1-like factor KW - Human beta -defensin 2 KW - ETS binding site KW - Perforin KW - Epithelial cells KW - Lysozyme KW - Invasiveness KW - Data processing KW - Nucleotide sequence KW - Antisense RNA KW - Transcription KW - Immunity KW - Electrophoretic mobility KW - Promoters KW - Defensins KW - RNA KW - Microorganisms KW - Antimicrobial peptides KW - A 01340:Antibiotics & Antimicrobials KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20484188?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEBS+Letters&rft.atitle=MEF+up-regulates+human+beta+-defensin+2+expression+in+epithelial+cells&rft.au=Lu%2C+Zhuo%3BKim%2C+Kyoung-Ah%3BSuico%2C+Mary+Ann%3BShuto%2C+Tsuyoshi%3BLi%2C+Jian-Dong%3BKai%2C+Hirofumi&rft.aulast=Lu&rft.aufirst=Zhuo&rft.date=2004-03-01&rft.volume=561&rft.issue=1-3&rft.spage=117&rft.isbn=&rft.btitle=&rft.title=FEBS+Letters&rft.issn=00145793&rft_id=info:doi/10.1016%2FS0014-5793%2804%2900138-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Lysozyme; Epithelial cells; Perforin; Invasiveness; Data processing; Nucleotide sequence; Antisense RNA; Transcription; Immunity; Electrophoretic mobility; Promoters; Defensins; RNA; Microorganisms; Antimicrobial peptides DO - http://dx.doi.org/10.1016/S0014-5793(04)00138-3 ER - TY - JOUR T1 - Latex allergy. AN - 200704981; 15074518 JF - Association of Operating Room Nurses. AORN Journal AU - Arthur, T AU - Bellistri, M AU - Butler, J AU - D'Intinosanto, M AU - Homer, J AU - Lenehan, G AU - O'Connor, E AU - Bain, E AU - Massachusetts Nurses Association Congress on Health and Safety AD - Massachusetts Nurses Association Congress on Health and Safety Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 579 EP - 80; author reply 582-4; discussion 584-5 CY - Denver PB - Elsevier Limited VL - 79 IS - 3 SN - 00012092 KW - Medical Sciences--Nurses And Nursing KW - Latex KW - United States KW - Humans KW - Latex -- adverse effects KW - Latex Hypersensitivity -- prevention & control KW - Gloves, Surgical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/200704981?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthcompleteshell&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Association+of+Operating+Room+Nurses.+AORN+Journal&rft.atitle=Latex+allergy.&rft.au=Arthur%2C+T%3BBellistri%2C+M%3BButler%2C+J%3BD%27Intinosanto%2C+M%3BHomer%2C+J%3BLenehan%2C+G%3BO%27Connor%2C+E%3BBain%2C+E%3BMassachusetts+Nurses+Association+Congress+on+Health+and+Safety&rft.aulast=Arthur&rft.aufirst=T&rft.date=2004-03-01&rft.volume=79&rft.issue=3&rft.spage=579&rft.isbn=&rft.btitle=&rft.title=Association+of+Operating+Room+Nurses.+AORN+Journal&rft.issn=00012092&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright National Library of Medicine - MEDLINE Abstracts Mar 2004 N1 - Last updated - 2014-04-21 ER - TY - JOUR T1 - Status of Marine Turtles in British Columbia Waters: A Reassessment AN - 19413524; 6121855 AB - Marine turtles in British Columbia have previously been considered off course stragglers. Here we document 20 new reports for Green Turtles, Chelonia mydas, and Leatherback Turtles, Dermochelys coriacea, for the province. Until recently there had been no concerted effort to acquire data on marine turtle abundance or frequency off British Columbia. Observations presented here allow a reassessment of marine turtle status in British Columbia waters. We suggest Green Turtles and Leatherbacks should be considered rare vagrants and uncommon seasonal residents, respectively, off British Columbia and that they are a natural part of the British Columbia marine environment. JF - Canadian Field-Naturalist AU - McAlpine, D F AU - Orchard, SA AU - Sendall, KA AU - Palm, R AD - World Wide Fund for Nature, GPO Box 528, Sydney, NSW 2001 Australia, dmcalpin@nb.aibn.com Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 72 EP - 76 VL - 118 IS - 1 SN - 0008-3550, 0008-3550 KW - Green sea turtle KW - Green turtle KW - Leatherback KW - Leatherback sea turtle KW - Oceanic Abstracts; Ecology Abstracts; Water Resources Abstracts KW - Marine KW - SW 0810:General KW - D 04670:Reptiles KW - O 1080:Multi-disciplinary Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19413524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Canadian+Field-Naturalist&rft.atitle=Status+of+Marine+Turtles+in+British+Columbia+Waters%3A+A+Reassessment&rft.au=McAlpine%2C+D+F%3BOrchard%2C+SA%3BSendall%2C+KA%3BPalm%2C+R&rft.aulast=McAlpine&rft.aufirst=D&rft.date=2004-03-01&rft.volume=118&rft.issue=1&rft.spage=72&rft.isbn=&rft.btitle=&rft.title=Canadian+Field-Naturalist&rft.issn=00083550&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-01-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Marine ER - TY - JOUR T1 - Roles of Genes 44, 50, and 51 in Regulating Gene Expression and Host Takeover during Infection of Bacillus subtilis by Bacteriophage SPO1 AN - 19261696; 5846284 AB - We show that the products of SPO1 genes 44, 50, and 51 are required for the normal transition from early to middle gene expression during infection of Bacillus subtilis by bacteriophage SPO1; that they are also required for control of the shutoff of host DNA, RNA, and protein synthesis; and that their effects on host shutoff could be accounted for by their effects on the regulation of gene expression. These three gene products had four distinguishable effects in regulating SPO1 gene expression: (i) gp44-50-51 acted to restrain expression of all SPO1 genes tested, (ii) gp44 and/or gp50-51 caused additional specific repression of immediate-early genes, (iii) gp44 and/or gp50- 51 stimulated expression of middle genes, and (iv) gp44 and/or gp50-51 stimulated expression of some delayed-early genes. Shutoff of immediate-early gene expression also required the activity of gp28, the middle-gene-specific sigma factor. Shutoff of host RNA and protein synthesis was accelerated by either the 44 super(-) single mutant or the 50 super(-)51 super(-) double mutant and more so by the 44 super(-)50 super(-)51 super(-) triple mutant. Shutoff of host DNA synthesis was accelerated by the mutants early in infection but delayed by the 44 super(-)50 super(- )51 super(-) triple mutant at later times. Although gp50 is a very small protein, consisting almost entirely of an apparent membrane-spanning domain, it contributed significantly to each activity tested. We identify SPO1 genes 41 to 51 and 53 to 60 as immediate-early genes; genes 27, 28, and 37 to 40 as delayed- early genes; and gene 52 as a middle gene. JF - Journal of Bacteriology AU - Sampath, A AU - Stewart, C R AD - Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77251, crs@bioc.rice.edu Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 1785 EP - 1792 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 186 IS - 6 SN - 0021-9193, 0021-9193 KW - gene 44 KW - gene 50 KW - gene 51 KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Genetics Abstracts KW - protein biosynthesis KW - DNA biosynthesis KW - Bacillus subtilis KW - mutants KW - Phage SPO1 KW - gene expression KW - G 07312:Phages KW - J 02750:Phage-host interactions KW - V 22070:Phage-host interactions including lysogeny & transduction UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19261696?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Bacteriology&rft.atitle=Roles+of+Genes+44%2C+50%2C+and+51+in+Regulating+Gene+Expression+and+Host+Takeover+during+Infection+of+Bacillus+subtilis+by+Bacteriophage+SPO1&rft.au=Sampath%2C+A%3BStewart%2C+C+R&rft.aulast=Sampath&rft.aufirst=A&rft.date=2004-03-01&rft.volume=186&rft.issue=6&rft.spage=1785&rft.isbn=&rft.btitle=&rft.title=Journal+of+Bacteriology&rft.issn=00219193&rft_id=info:doi/10.1128%2FJB.186.6.1785-1792.2004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Bacillus subtilis; Phage SPO1; mutants; DNA biosynthesis; protein biosynthesis; gene expression DO - http://dx.doi.org/10.1128/JB.186.6.1785-1792.2004 ER - TY - JOUR T1 - Effect of inoculum density of Sclerotium cepivorum on the ability of Trichoderma koningii to suppress white rot of onion AN - 17996109; 5935911 AB - Amendment of soil with Trichoderma koningii strain Tr5 grown on autoclaved white millet grain provided between 63 and 79% control of white rot of onion when added to soil containing 10, 25, 50, or 100 sclerotia of Sclerotium cepivorum per kilogram of soil at the time of onion seed sowing. There was no significant difference in the proportion of S. cepivorum infections suppressed among the different sclerotial density treatments. Rhizosphere colonization by T. koningii Tr5 was assessed by incubating onion roots sampled from plants growing in soil with the appropriate density of sclerotia, on a Trichoderma selective medium (Rose bengall-Allisan-streptomycin-Previcur agar) developed for the purpose of the study. Trichoderma spp. isolated were typed by comparison of culture morphology as well as polygalacturonase (PG) (EC 3.2.1.15) and pectinesterase (PE) (EC 3.1.1.11) isozyme profiles to the series of one PG and two PE isozymes known to be produced by T. koningii Tr5. The method was used successfully to assess rhizosphere colonization. Three rates of a millet grain formulation colonized by T. koningii Tr5 were added to soil (1,590, 3,180, and 4,770 kg/ha). At the lowest of these rates, 97% of roots were found to be colonized by isolates which could not be distinguished from T. koningii Tr5, whereas 8% of the roots from nontreated controls were colonized by such isolates. An objective of the study was to determine whether the ability of T. koningii Tr5 to suppress S. cepivorum infections was influenced by increased concentrations of both S. cepivorum sclerotia and T. koningii Tr5-colonized millet grain, and it was found that no further improvements in the percentage of disease suppression were recorded as a result of adding T. koningii TrS-colonized millet to the soil at more than 1,590 kg/ha at any of the sclerotium concentrations tested. JF - Plant Disease AU - Metcalf, DA AU - Dennis, JJC AU - Wilson, C R AD - Tasmanian Institute of Agricultural Research, New Town Research Laboratories, GPO Box 44, Hobart, Tasmania 7001, Australia, Dean.Metcalf@dpiwe.tas.gov.au Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 287 EP - 291 VL - 88 IS - 3 SN - 0191-2917, 0191-2917 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Biological control KW - Sclerotium cepivorum KW - Plant diseases KW - Rhizosphere KW - Soil KW - White rot KW - Colonization KW - Trichoderma koningii KW - A 01028:Others KW - K 03089:Fungi: plant UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17996109?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Disease&rft.atitle=Effect+of+inoculum+density+of+Sclerotium+cepivorum+on+the+ability+of+Trichoderma+koningii+to+suppress+white+rot+of+onion&rft.au=Metcalf%2C+DA%3BDennis%2C+JJC%3BWilson%2C+C+R&rft.aulast=Metcalf&rft.aufirst=DA&rft.date=2004-03-01&rft.volume=88&rft.issue=3&rft.spage=287&rft.isbn=&rft.btitle=&rft.title=Plant+Disease&rft.issn=01912917&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Sclerotium cepivorum; Trichoderma koningii; Plant diseases; White rot; Biological control; Soil; Rhizosphere; Colonization ER - TY - JOUR T1 - Changes in Cognitive Measures in a Randomized Controlled Trial of a Health Promotion Program for Couples Targeting Diet and Physical Activity AN - 17923037; 5868980 AB - To examine cognitive responses to a 4-month health promotion program targeting diet and physical activity in recently cohabiting couples. A three-group randomized controlled trial: no intervention (Controls), interactive group sessions and mail-outs (Interactive), and one group session followed by mail-outs (Mail). Australian research studies unit. Seventy-eight of 137 couples cohabiting for <2 years, recruited by advertising, completed the study. Stages of change; health beliefs; self-efficacy; and perceived barriers to change evaluated by questionnaires at baseline, postintervention, and 1-year follow-up. Data were analyzed using mixed models, factor analysis, and linear regression. In the Mail group, the perceived importance of barriers to dietary change decreased by 19% at postintervention and 16% at 1-year follow-up; dietary self-efficacy increased by 9% and 3%, respectively. In the Interactive group, the perceived importance of barriers to dietary change decreased by 26% and 20%, and dietary self-efficacy increased by 14% and 12%, respectively. Similar trends for physical activity were not statistically significant. However changes in self-efficacy and perceived barriers to change significantly predicted dietary and physical activity behaviors. A preponderance of higher socio-economic groups and the proportion of drop-out may have biased results. Health promotion using partners' support and targeting diet and physical activity improves associated cognitive variables in couples. Most improvements were greater and more sustained with interactive group sessions. JF - American Journal of Health Promotion AU - Burke, V AU - Giangiulio, N AU - Gillam, H F AU - Beilin, L J AU - Houghton, S AD - University Department of Medicine, Royal Perth Hospital, Box X2213 GPO, Perth 6847, Australia Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 300 EP - 311 VL - 18 IS - 4 SN - 0890-1171, 0890-1171 KW - Physical Education Index KW - Diet (effects) KW - Mental ability KW - Health (status) KW - Wellness KW - Exercise (effects) KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17923037?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Health+Promotion&rft.atitle=Changes+in+Cognitive+Measures+in+a+Randomized+Controlled+Trial+of+a+Health+Promotion+Program+for+Couples+Targeting+Diet+and+Physical+Activity&rft.au=Burke%2C+V%3BGiangiulio%2C+N%3BGillam%2C+H+F%3BBeilin%2C+L+J%3BHoughton%2C+S&rft.aulast=Burke&rft.aufirst=V&rft.date=2004-03-01&rft.volume=18&rft.issue=4&rft.spage=300&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Health+Promotion&rft.issn=08901171&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Health (status); Diet (effects); Mental ability; Wellness; Exercise (effects) ER - TY - JOUR T1 - Use of chemometrics methods and multicriteria decision-making for site selection for sustainable on-site sewage effluent disposal AN - 16165106; 5828955 AB - This paper presents a study undertaken to evaluate site suitability for sewage effluent renovation based on physico-chemical characteristics of the soil. The results obtained showed that as the soil becomes acidic, the phosphorus concentration in the soil reduces accordingly. The chloride ion concentration was found to be a reliable indicator for evaluating the soil capacity to remove nitrogen. A high cation exchange capacity (CEC) can enhance the renovation of sewage effluent. Soils with high quartz content had a low CEC with high organic matter content (OM) being able to compensate. Therefore, an understanding of the micro-nutrients in the soil, organic matter content and chloride ion concentration are important. To facilitate a multi-variate approach for site selection, multicriteria decision-making (MCDM) methods, PROMETHEE and GAIA, were applied for analysis of a sequence of three matrices consisting of 8, 16, and 48 soil site objects, respectively, and seven soil property parameters. Matrix models and the interpretation of results are discussed in detail. From these analyses, PROMETH IIEE net outranking flows, [curly or open small phi], found that two sites were always among the top three ranks of the three matrix models, which suggested that they were the most suitable for sewage effluent renovation. The criteria CEC and OM, were particularly important for the selection of these better sites, but pH and Cl super(-) attributes discriminated the weaker performing sites from the better ones; as well the PO sub(4) super(3-) and the NH sub(3)-N criteria were in general opposition to CEC, OM, pH and Cl super(-) but were much less effective as discriminators. Consideration of net outranking flows suggested an approach method for the selection of other possibly suitable sites for sewage effluent renovation. JF - Analytica Chimica Acta AU - Khalil, WA-S AU - Goonetilleke, A AU - Kokot, S AU - Carroll, S AD - School of Civil Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001, Australia, w.khalil@qut.edu.au Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 41 EP - 56 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 506 IS - 1 SN - 0003-2670, 0003-2670 KW - Sustainability Science Abstracts; Water Resources Abstracts; Pollution Abstracts; Aqualine Abstracts KW - Chemometrics methods KW - Land capability KW - PROMETHEE and GAIA KW - Sewage effluent disposal KW - Subsurface effluent disposal KW - Siting criteria KW - Soil Contamination KW - Effluent disposal KW - Physicochemical Properties KW - Physicochemical properties KW - decision making KW - Nitrogen Removal KW - Decision Making KW - Soil KW - Sewage KW - Wastewater Disposal KW - P 3000:SEWAGE & WASTEWATER TREATMENT KW - SW 3050:Ultimate disposal of wastes KW - AQ 00006:Sewage KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16165106?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytica+Chimica+Acta&rft.atitle=Use+of+chemometrics+methods+and+multicriteria+decision-making+for+site+selection+for+sustainable+on-site+sewage+effluent+disposal&rft.au=Khalil%2C+WA-S%3BGoonetilleke%2C+A%3BKokot%2C+S%3BCarroll%2C+S&rft.aulast=Khalil&rft.aufirst=WA-S&rft.date=2004-03-01&rft.volume=506&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Analytica+Chimica+Acta&rft.issn=00032670&rft_id=info:doi/10.1016%2Fj.aca.2003.11.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-02-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Soil; Siting criteria; Sewage; Effluent disposal; Physicochemical properties; decision making; Soil Contamination; Physicochemical Properties; Wastewater Disposal; Decision Making; Nitrogen Removal DO - http://dx.doi.org/10.1016/j.aca.2003.11.003 ER - TY - JOUR T1 - Effects of Particulate Air Pollution on Blood Pressure and Heart Rate in Subjects with Cardiovascular Disease: a Multicenter Approach AN - 14694484; 10659255 AB - As part of the European multicenter study on exposure and risk assessment for ambient fine and ultrafine particles, blood pressure and heart rate were measured in subjects with preexisting heart disease. The study subjects were from Amsterdam, Netherlands; Erfurt, Germany; and Helsinki, Finland. The study protocol consisted of clinical visits once every two weeks and daily recording of symptoms and medication use, and in each city, concentrations of ambient air pollutants were measured at a fixed site representing urban background levels. A small decrease in diastolic as well as systolic blood pressure in the subjects was associated with fine particles and gaseous air pollution, which was driven mostly by patients with prior myocardial infarction. In addition, a slight decrease in heart rate was associated with a 2-d lagged exposure to ambient particle concentrations. Effects of ultrafine particles on blood pressure in supine as well as in standing position were significant for the Erfurt subjects and consistent across all exposure variables. JF - Environmental Health Perspectives AU - Ibald-Mulli, Angela AU - Timonen, Kirsi L AU - Peters, Annette AU - Heinrich, Joachim AU - Wolke, Gabriele AU - Lanki, Timo AU - Buzorius, Gintautas Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 369 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - BLOOD PRESSURE KW - PARTICULATES KW - URBAN ATMOSPHERE KW - GERMANY KW - HEART DISEASE KW - NETHERLANDS KW - FINLAND KW - CARDIOVASCULAR DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694484?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+Particulate+Air+Pollution+on+Blood+Pressure+and+Heart+Rate+in+Subjects+with+Cardiovascular+Disease%3A+a+Multicenter+Approach&rft.au=Ibald-Mulli%2C+Angela%3BTimonen%2C+Kirsi+L%3BPeters%2C+Annette%3BHeinrich%2C+Joachim%3BWolke%2C+Gabriele%3BLanki%2C+Timo%3BBuzorius%2C+Gintautas&rft.aulast=Ibald-Mulli&rft.aufirst=Angela&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=369&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 15 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; HEART DISEASE; NETHERLANDS; FINLAND; BLOOD PRESSURE; GERMANY; URBAN ATMOSPHERE; PARTICULATES; CARDIOVASCULAR DISORDERS ER - TY - JOUR T1 - Thyroid Toxicants: Assessing Reproductive Health Effects AN - 14694426; 10659254 AB - Findings are summarized briefly from a recent international conference on thyroid gland and brain development. The comparative physiology of rodent and human thyroid systems was presented, focusing on the relevance of thyroid-related adverse reproductive and developmental outcomes observed in rodents for predicting health risks to humans. An overview is provided of the similarities and differences between the human and rodent thyroid systems, as well as the reproductive effects of selected thyroid-active chemicals in rodents and humans, and an assessment of the adequacy of existing rodent toxicity testing models for assessing human thyroid health hazards. JF - Environmental Health Perspectives AU - Jahnke, Gloria D AU - Choksi, Neepa Y AU - Moore, John A AU - Shelby, Michael D Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 363 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PATHOLOGY, ANIMAL KW - PATHOLOGY, HUMAN KW - HORMONAL EFFECTS KW - SPECIES COMPARISONS KW - REPRODUCTION, HUMAN KW - REPRODUCTION, ANIMAL KW - THYROID FUNCTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Thyroid+Toxicants%3A+Assessing+Reproductive+Health+Effects&rft.au=Jahnke%2C+Gloria+D%3BChoksi%2C+Neepa+Y%3BMoore%2C+John+A%3BShelby%2C+Michael+D&rft.aulast=Jahnke&rft.aufirst=Gloria&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=363&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PATHOLOGY, ANIMAL; SPECIES COMPARISONS; PATHOLOGY, HUMAN; REPRODUCTION, HUMAN; HORMONAL EFFECTS; REPRODUCTION, ANIMAL; THYROID FUNCTION ER - TY - JOUR T1 - Critical Periods for Chlorpyrifos-Induced Developmental Neurotoxicity: Alterations in Adenylyl Cyclase Signaling in Adult Rat Brain Regions After Gestational or Neonatal Exposure AN - 14694324; 10659243 AB - Using rats, the long-term impact of gestational or neonatal chlorpyrifos exposure on the functioning of the adenylyl cyclase (AC) signaling cascade was investigated, focusing on four different critical windows: the formation of the neural tube, the late gestational period, and postnatal phases of terminal neuronal differentiation and synaptogenesis. Chlorpyrifos doses were chosen to examine whether the threshold for effects on AC signaling was below that for systemic toxicity and/or inhibition of cholinesterase. Results indicated that exposure to chlorpyrifos during development elicited long-term alterations in AC-mediated cell signaling in the central nervous system, with differential effects according to sex and brain region that depended on the exposure period. Four major features of the lasting alterations of AC signaling were observed: regional selectivity, existence of a peak period of sensitivity, localization of the effects to specific signaling proteins, and preferential effects according to sex. Effects of chlorpyrifos on AC signaling components were observed in both early- and late-developing regions with either gestational or postnatal exposures. JF - Environmental Health Perspectives AU - Meyer, Armando AU - Seidler, Frederic J AU - Aldridge, Justin E AU - Tate, Charlotte A AU - Cousins, Mandy M AU - Slotkin, Theodore A Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 295 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - NEUROTOXICITY KW - CHLORPYRIFOS KW - AGE COMPARISONS KW - RATS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Critical+Periods+for+Chlorpyrifos-Induced+Developmental+Neurotoxicity%3A+Alterations+in+Adenylyl+Cyclase+Signaling+in+Adult+Rat+Brain+Regions+After+Gestational+or+Neonatal+Exposure&rft.au=Meyer%2C+Armando%3BSeidler%2C+Frederic+J%3BAldridge%2C+Justin+E%3BTate%2C+Charlotte+A%3BCousins%2C+Mandy+M%3BSlotkin%2C+Theodore+A&rft.aulast=Meyer&rft.aufirst=Armando&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 13 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; NEUROTOXICITY; CHLORPYRIFOS; AGE COMPARISONS; RATS ER - TY - JOUR T1 - Urinary Levels of Seven Phthalate Metabolites in the U.S. Population from the National Health and Nutrition Examination Survey (NHANES) 19992000 AN - 14694273; 10659249 AB - Phthalate monoester metabolites were used as markers to assess phthalate exposure in the general US population. The urine specimens analyzed were collected from participants of the National Health and Nutrition Examination Survey conducted in 19992000. Resulting data are presented on concentrations of monoethyl phthalate (MEP), monobutyl phthalate (MBP), monobenzyl phthalate (MBzP), and mono-(2-ethylhexyl) phthalate (MEHP). The data reveal that MEP, MBP, and MBzP were detected in more than 97% of the samples, and MEHP was detected in more than 75%, indicating widespread exposure. Higher urinary concentrations of MEP, MBP, and MBzP than MEHP were found. Higher MEP concentrations were found in adults and adolescents than in children, and women had higher concentrations than men. The concentrations of MBzP and MBP were correlated highly, as were the concentrations of MBP and both MEP and MEHP. The levels of MEHP, MBzP, and MBP were higher in children than in adolescents and adults. Mono-cyclohexyl phthalate, mono-n-octyl phthalate, and mono-3-methyl-5-dimethylhexyl phthalate were found in less than 20% of the samples. JF - Environmental Health Perspectives AU - Silva, Manori J AU - Barr, Dana B AU - Reidy, John A AU - Malek, Nicole A AU - Hodge, Carolyn C AU - Caudill, Samuel P AU - Brock, John W Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 331 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - PHTHALIC ACID ESTERS KW - AGE COMPARISONS KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Urinary+Levels+of+Seven+Phthalate+Metabolites+in+the+U.S.+Population+from+the+National+Health+and+Nutrition+Examination+Survey+%28NHANES%29+1999%26lt%3BND%26gt%3B2000&rft.au=Silva%2C+Manori+J%3BBarr%2C+Dana+B%3BReidy%2C+John+A%3BMalek%2C+Nicole+A%3BHodge%2C+Carolyn+C%3BCaudill%2C+Samuel+P%3BBrock%2C+John+W&rft.aulast=Silva&rft.aufirst=Manori&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=331&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; PHTHALIC ACID ESTERS; AGE COMPARISONS; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Reductions in Blood Lead Overestimate Reductions in Brain Lead After Repeated Succimer Regimens in a Rodent Model of Childhood Lead Exposure AN - 14693545; 10659244 JF - Environmental Health Perspectives AU - Stangle, Diane E AU - Strawderman, Myla S AU - Smith, Donald AU - Kuypers, Mareike AU - Strupp, Barbara J Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 302 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - LEAD POISONING KW - BLOOD LEAD LEVEL KW - CHELATING AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14693545?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Reductions+in+Blood+Lead+Overestimate+Reductions+in+Brain+Lead+After+Repeated+Succimer+Regimens+in+a+Rodent+Model+of+Childhood+Lead+Exposure&rft.au=Stangle%2C+Diane+E%3BStrawderman%2C+Myla+S%3BSmith%2C+Donald%3BKuypers%2C+Mareike%3BStrupp%2C+Barbara+J&rft.aulast=Stangle&rft.aufirst=Diane&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=302&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; LEAD POISONING; BLOOD LEAD LEVEL; CHELATING AGENTS ER - TY - JOUR T1 - Overview of the Application of Transcription Profiling Using Selected Nephrotoxicants for Toxicology Assessment AN - 14693480; 10659589 AB - An overview is provided of the experimental work performed by the Nephrotoxicity Working Group, which was formed by the Health and Environmental Sciences Institute Genomics Committee to explore the integration of emerging transcription profiling technologies into traditional safety assessment evaluations. Three model nephrotoxins-cisplatin, gentamicin, and puromycin-were used, for which transcriptional profiles were established using male SpragueDawley rats. A preliminary in vivo study was conducted to determine the technical parameters for tissue and RNA isolation, and microarray analyses were performed on oligonucleotide and cDNA-based platforms at different laboratories. Described are the analysis of platform variability and the handling of mechanistic and topographic information. The experiments reproduced the topographically and mechanistically distinct renal lesion associated with exposure to the compounds, and at least equal sensitivity of microarray technology was found compared to traditional toxicological endpoints. JF - Environmental Health Perspectives AU - Kramer, Jeffrey A AU - Pettit, Syril D AU - Amin, Rupesh P AU - Bertram, Timothy A AU - Car, Bruce AU - Cunningham, Michael AU - Curtiss, Sandra W Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 460 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - GENETICS, ANIMAL KW - NEPHROTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14693480?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Overview+of+the+Application+of+Transcription+Profiling+Using+Selected+Nephrotoxicants+for+Toxicology+Assessment&rft.au=Kramer%2C+Jeffrey+A%3BPettit%2C+Syril+D%3BAmin%2C+Rupesh+P%3BBertram%2C+Timothy+A%3BCar%2C+Bruce%3BCunningham%2C+Michael%3BCurtiss%2C+Sandra+W&rft.aulast=Kramer&rft.aufirst=Jeffrey&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=460&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; GENETICS, ANIMAL; NEPHROTOXICITY ER - TY - JOUR T1 - Abnormal Bone Composition in Female Juvenile American Alligators from a Pesticide-Polluted Lake (Lake Apopka, Florida) AN - 14693366; 10659253 AB - Juvenile female American alligators Alligator mississippiensis were collected from two lakes in central Florida, and bone composition was examined and compared. The study sites were pesticide-contaminated Lake Apopka and uncontaminated Lake Woodruff. The tibia and femur were dissected free from soft tissue, and bone composition and dimensions were evaluated by peripheral quantitative computed tomography. The tibial diaphyseal total bone mineral density in animals from Lake Apopka was significantly greater than that in animals from the reference lake, which was also found for the tibial trabecular bone mineral density. In addition, the trabecular bone mineral content was 75% greater in females from Lake Apopka. The femoral metaphyseal total bone mineral density and the femur trabecular bone mineral density in females from Lake Apopka were 12 and 30% greater, respectively, that the Lake Woodruff values. The overall results suggested that alligators from Lake Apopka were exposed to estrogenic compounds, as the observations were characteristic of estrogen exposure in other vertebrates. JF - Environmental Health Perspectives AU - Lind, PMonica AU - Milnes, Matthew R AU - Lundberg, Rebecca AU - Bermudez, Dieldrich AU - Orberg, Jan AU - Guillette, Louis J Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 359 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BONE DISORDERS KW - HORMONAL EFFECTS KW - FLORIDA KW - ALLIGATORS KW - PESTICIDE EXPOSURE KW - WATER POLLUTION EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14693366?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Abnormal+Bone+Composition+in+Female+Juvenile+American+Alligators+from+a+Pesticide-Polluted+Lake+%28Lake+Apopka%2C+Florida%29&rft.au=Lind%2C+PMonica%3BMilnes%2C+Matthew+R%3BLundberg%2C+Rebecca%3BBermudez%2C+Dieldrich%3BOrberg%2C+Jan%3BGuillette%2C+Louis+J&rft.aulast=Lind&rft.aufirst=PMonica&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=359&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BONE DISORDERS; HORMONAL EFFECTS; ALLIGATORS; PESTICIDE EXPOSURE; FLORIDA; WATER POLLUTION EFFECTS ER - TY - JOUR T1 - Glyphosate Biomonitoring for Farmers and Their Families: Results from the Farm Family Exposure Study AN - 14693291; 10659247 AB - The Farm Family Exposure Study quantified real-world pesticide exposures immediately before, during, and after a pesticide application and identified significant exposure determinants. The families were selected randomly from licensed pesticide applicators from state listings in South Carolina and Minnesota. Urine specimens were collected from individuals of 48 families and analyzed for glyphosate concentrations. Systemic doses were estimated for each individual who had detectable urinary levels of glyphosate by calculating the amount excreted during the study period, adjusting for incomplete excretion, adjusting for pharmacokinetic recovery, and dividing the total corrected excretion by each individual's body weight. Results showed that exposure potential was especially limited for those not present in the immediate area of pesticide mixing, loading, or application activities. Highest values for farmers were associated with not wearing rubber gloves when handling the pesticide formulation. In addition, the number of mixing/loading operations, observed spills, and repairing equipment were associated with appreciable differences in average urinary glyphosate values. JF - Environmental Health Perspectives AU - Acquavella, John F AU - Alexander, Bruce H AU - Mandel, Jack S AU - Gustin, Christophe AU - Baker, Beth AU - Chapman, Pamela AU - Bleeke, Marian Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 321 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PESTICIDE EXPOSURE KW - BIOACCUMULATION, HUMAN KW - PESTICIDE USAGE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14693291?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Glyphosate+Biomonitoring+for+Farmers+and+Their+Families%3A+Results+from+the+Farm+Family+Exposure+Study&rft.au=Acquavella%2C+John+F%3BAlexander%2C+Bruce+H%3BMandel%2C+Jack+S%3BGustin%2C+Christophe%3BBaker%2C+Beth%3BChapman%2C+Pamela%3BBleeke%2C+Marian&rft.aulast=Acquavella&rft.aufirst=John&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=321&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PESTICIDE EXPOSURE; PESTICIDE USAGE; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Quantitative PCR Deconstruction of Discrepancies Between Results Reported by Different Hybridization Platforms AN - 14693083; 10659588 JF - Environmental Health Perspectives AU - Goodsaid, Federico M AU - Smith, Roger J AU - Rosenblum, I Y Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 456 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14693083?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Quantitative+PCR+Deconstruction+of+Discrepancies+Between+Results+Reported+by+Different+Hybridization+Platforms&rft.au=Goodsaid%2C+Federico+M%3BSmith%2C+Roger+J%3BRosenblum%2C+I+Y&rft.aulast=Goodsaid&rft.aufirst=Federico&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=456&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; HEPATOTOXICITY ER - TY - JOUR T1 - Unraveling GeneGene Interactions Regulated by Ligands of the Aryl Hydrocarbon Receptor AN - 14693024; 10659581 AB - Results are presented from a study in which biological networks regulated by ligands of the aryl hydrocarbon receptor (Ahr) were unraveled. Polycyclic aromatic hydrocarbon contaminants and byproducts of aspartate aminotransferase metabolism have been identified as ligands of the Ahr. The target genes chosen for the study included Ahr, cytochrome P4501B1, insulin-like growth factor-binding protein-5, lysyl oxidase, and osteopontin. Gene networks were defined on the basis of the co-determination of transcriptional states resolved by statistical evaluation of data sets derived from large-scale simultaneous measurements made using Affymetrix microarray technology. The expression of 200 genes across 40 different arrays from three different tissues after activation of Ahr signaling was used to predict the behavior of the selected targets. As a biological target, Ahr was predicted best by lymphocyte antigen 63, a retinoic acid-responsive gene involved in T-cell activation, while cytochrome P4501B1 was predicted by syk tyrosine kinase in all cases. JF - Environmental Health Perspectives AU - Johnson, Charles D AU - Balagurunathan, Yoganand AU - Tadesse, Mahlet G AU - Falahatpisheh, MHadi AU - Brun, Marcel AU - Walker, Mary K AU - Dougherty, Edward R Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 403 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CARCINOGENIC MECHANISMS KW - GENETIC ENGINEERING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14693024?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Unraveling+Gene%26lt%3BND%26gt%3BGene+Interactions+Regulated+by+Ligands+of+the+Aryl+Hydrocarbon+Receptor&rft.au=Johnson%2C+Charles+D%3BBalagurunathan%2C+Yoganand%3BTadesse%2C+Mahlet+G%3BFalahatpisheh%2C+MHadi%3BBrun%2C+Marcel%3BWalker%2C+Mary+K%3BDougherty%2C+Edward+R&rft.aulast=Johnson&rft.aufirst=Charles&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=403&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CARCINOGENIC MECHANISMS; GENETIC ENGINEERING ER - TY - JOUR T1 - Toward the Effective Surveillance of Hypospadias AN - 14692999; 10659260 AB - Hypospadias is a congenital abnormality of the male genitalia characterized by incomplete development of the urethra, and data have suggested a link between the abnormality and exposure to endocrine-disrupting chemicals. In this study, data were obtained from the European Surveillance of Congenital Anomalies (EUROCAT) and from the National Congenital Anomaly System (NCAS), which reports congenital anomalies in England and Wales, to document the prevalence of hypospadias since 1980. The EUROCAT guidelines specify that hypospadias is to be registered with the exclusion of the most distal cases where the meatus lies before the coronary sulcus, glanular, or first-degree hypospadias. Since 1990, NCAS was operated with the same exclusion guideline for distal hypospadias. Analysis of the data revealed variable quality, as the exclusion guideline was not always followed. However, the data did not suggest a rising prevalence of hypospadias in Europe. Recommendations are proposed for future hypospadias surveillance practice. JF - Environmental Health Perspectives AU - Dolk, Helen AU - Vrijheid, Martine AU - Scott, John ES AU - Addor, Marie-Claude AU - Botting, Bev AU - de Vigan, Catherine AU - de Walle, Hermien Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 398 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEDICAL SURVEILLANCE KW - DISEASES AND DISORDERS KW - HORMONAL EFFECTS KW - EUROPE KW - UNITED KINGDOM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692999?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Toward+the+Effective+Surveillance+of+Hypospadias&rft.au=Dolk%2C+Helen%3BVrijheid%2C+Martine%3BScott%2C+John+ES%3BAddor%2C+Marie-Claude%3BBotting%2C+Bev%3Bde+Vigan%2C+Catherine%3Bde+Walle%2C+Hermien&rft.aulast=Dolk&rft.aufirst=Helen&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=398&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEDICAL SURVEILLANCE; DISEASES AND DISORDERS; HORMONAL EFFECTS; EUROPE; UNITED KINGDOM ER - TY - JOUR T1 - Androgenic and Estrogenic Activity in Water Bodies Receiving Cattle Feedlot Effluent in Eastern Nebraska, USA AN - 14692952; 10659251 AB - Water was collected over a 3-yr period from six sites confluent with the Elkhorn River, NE, one of which was a feedlot retention pond, and hormonal contamination was assessed. Total androgenic and estrogenic activity was determined using the A-SCREEN and the E-SCREEN bioassays, and concentrations of anabolic agents were measured using gas chromatographymass spectroscopy and enzyme-based immunoassays. Results indicated that the total androgenic activity measured by the A-SCREEN appeared to have originated in the feedlots because it was highest in the feedlot retention pond and decreased downstream. The estrogenic activities measured at the feedlot retention pond and at the site located 0.5 km downstream were sufficient to produce a significant effect on target cells. Resorcylic acid lactones were not detected, but estrone was detected at all sites and represented up to 46% of the total estrogenic activity. JF - Environmental Health Perspectives AU - Soto, Ana M AU - Calabro, Janine M AU - Prechtl, Nancy V AU - Yau, Alice Y AU - Orlando, Edward F AU - Daxenberger, Andreas AU - Kolok, Alan S Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 346 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEBRASKA KW - LIVESTOCK FEEDLOT RUNOFF KW - SPATIAL COMPARISONS KW - WATER ANALYSIS KW - HORMONES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692952?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Androgenic+and+Estrogenic+Activity+in+Water+Bodies+Receiving+Cattle+Feedlot+Effluent+in+Eastern+Nebraska%2C+USA&rft.au=Soto%2C+Ana+M%3BCalabro%2C+Janine+M%3BPrechtl%2C+Nancy+V%3BYau%2C+Alice+Y%3BOrlando%2C+Edward+F%3BDaxenberger%2C+Andreas%3BKolok%2C+Alan+S&rft.aulast=Soto&rft.aufirst=Ana&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=346&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEBRASKA; LIVESTOCK FEEDLOT RUNOFF; SPATIAL COMPARISONS; WATER ANALYSIS; HORMONES ER - TY - JOUR T1 - Agricultural and Residential Pesticides in Wipe Samples from Farmworker Family Residences in North Carolina and Virginia AN - 14692931; 10659257 AB - In 41 farm households in North Carolina and Virginia, wipe samples were collected from floor, toys, and children's hands and analyzed for the presence of agricultural and residential pesticides. Observations were also made of the general environment of each dwelling, and interviews were conducted to ascertain the characteristics of the household residents and cleaning practices. The most-commonly detected agricultural pesticides were oxyfluorfen and simazine, and the most-commonly detected residential pesticide was trans-permethrin. In 49% of the households, at last one agricultural pesticide was detected in any location, and at least one residential pesticide was detected in 95% of the households. A strong positive association was found between detecting agricultural pesticides in toy wipes and in floor wipes, and there was a strong positive association between floor wipe and hand detections. Similarly strong associations were found for residential pesticides. An elevated risk of agricultural pesticides was observed when agricultural fields were adjacent to the house. Houses judged difficult to clean and rented housing were associated positively with increased odds of a higher number of residential pesticides. JF - Environmental Health Perspectives AU - Quandt, Sara A AU - Arcury, Thomas A AU - Rao, Pamela AU - Snively, Beverly M AU - Camann, David E AU - Doran, Alicia M AU - Yau, Alice Y Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 382 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PESTICIDE RESIDUES KW - PESTICIDE USAGE, RESIDENTIAL KW - AGRICULTURAL CHEMICALS KW - DUST KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Agricultural+and+Residential+Pesticides+in+Wipe+Samples+from+Farmworker+Family+Residences+in+North+Carolina+and+Virginia&rft.au=Quandt%2C+Sara+A%3BArcury%2C+Thomas+A%3BRao%2C+Pamela%3BSnively%2C+Beverly+M%3BCamann%2C+David+E%3BDoran%2C+Alicia+M%3BYau%2C+Alice+Y&rft.aulast=Quandt&rft.aufirst=Sara&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=382&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PESTICIDE RESIDUES; PESTICIDE USAGE, RESIDENTIAL; DUST; AGRICULTURAL CHEMICALS; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Clofibrate-Induced Gene Expression Changes in Rat Liver: a Cross-Laboratory Analysis Using Membrane cDNA Arrays AN - 14692830; 10659585 AB - As part of the experimental program of the Hepatotoxicity Working Group, established via a program initiated by the Health and Environmental Science Institute Technical Committee on the Application of Genomics to Mechanism-Based Risk Assessment, the biological response in rats to the model hepatotoxicant, clofibrate, was investigated. Doses of 25 and 250 mg/kg/d were chosen to investigate whether the gene expression profiles observed after exposure correlated with changes in known biological markers of hepatotoxicity. In addition, the reproducibility of the gene expression changes was assessed across different laboratories on a single microarray platform using RNA from identical in vivo studies conducted separately at different locations. The studies generally produced expected outcomes with regard to changes in clinical chemistry and histopathology, although some differences were demonstrated. Evaluation of differential gene expression data from the three laboratories performing microarray analysis revealed gene expression patterns that were consistent with the established literature for this class of compound. JF - Environmental Health Perspectives AU - Baker, Valerie A AU - Harries, Helen M AU - Waring, Jeff F AU - Duggan, Colette M AU - Ni, Hong A AU - Jolly, Robert A AU - Yoon, Lawrence W Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 428 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - DNA KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Clofibrate-Induced+Gene+Expression+Changes+in+Rat+Liver%3A+a+Cross-Laboratory+Analysis+Using+Membrane+cDNA+Arrays&rft.au=Baker%2C+Valerie+A%3BHarries%2C+Helen+M%3BWaring%2C+Jeff+F%3BDuggan%2C+Colette+M%3BNi%2C+Hong+A%3BJolly%2C+Robert+A%3BYoon%2C+Lawrence+W&rft.aulast=Baker&rft.aufirst=Valerie&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=428&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; DNA; HEPATOTOXICITY ER - TY - JOUR T1 - The Utility of DNA Microarrays for Characterizing Genotoxicity AN - 14692810; 10659583 AB - An overview is provided of research activities of the Genotoxicity Working Group of the International Life Sciences Institute Health and Environmental Sciences Institute Committee on the Application of Genomics to Mechanism-Based Risk Assessment. The collaborative project has evaluated the utility of gene expression profile analysis for risk assessment of genotoxicants, aimed specifically at analyzing gene expression profiles of compounds with known mechanisms of genotoxicity to determine whether compounds from different mechanistic classes display distinct gene expression profiles. The research has shown that observed changes in gene expression have been consistent with literature data on previously studied chemicals. While the induction of gene expression changes has been found not to be as sensitive an indicator of genotoxicity compared with more traditional genotoxicity endpoints, the changes could enable one to distinguish classes of genotoxic compounds that operate via different modes of action. JF - Environmental Health Perspectives AU - Newton, Ronald K AU - Aardema, Marilyn AU - Aubrecht, Jiri Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 420 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MUTAGENIC AGENTS KW - GENETICS, HUMAN KW - TOXICOLOGY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Utility+of+DNA+Microarrays+for+Characterizing+Genotoxicity&rft.au=Newton%2C+Ronald+K%3BAardema%2C+Marilyn%3BAubrecht%2C+Jiri&rft.aulast=Newton&rft.aufirst=Ronald&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=420&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MUTAGENIC AGENTS; TOXICOLOGY; GENETICS, HUMAN ER - TY - JOUR T1 - Interlaboratory Evaluation of Rat Hepatic Gene Expression Changes Induced by Methapyrilene AN - 14692753; 10659586 AB - The Health and Environmental Sciences Institute of the International Life Sciences Institute formed the Hepatotoxicity Working Group to investigate changes in rat hepatic gene expression upon exposure to the known hepatotoxin, methapyrilene (MP). The study was designed to assess the reproducibility of gene changes across different laboratories. In the in vivo study, male SpragueDawley rats were dosed daily for 7 d with 10 or 100 mg MP/kg, and RNA samples were analyzed independently by five different laboratories. Striking differences were found between the different laboratories, and further data analysis corroborated the findings that differences between Affymetrix users, sample processing, and hybridization protocols affected the absolute results. However, all users obtained similar overall results that correlated with histopathology and clinical chemistry analysis, with a clear differentiation obtained by all users between high- and low-dose-treated animals. JF - Environmental Health Perspectives AU - Waring, Jeffrey F AU - Ulrich, Roger G AU - Flint, Nick AU - Morfitt, David AU - Kalkuhl, Arno AU - Staedtler, Frank AU - Lawton, Michael Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 439 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - DOSE RESPONSE PROFILES KW - DNA KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692753?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Interlaboratory+Evaluation+of+Rat+Hepatic+Gene+Expression+Changes+Induced+by+Methapyrilene&rft.au=Waring%2C+Jeffrey+F%3BUlrich%2C+Roger+G%3BFlint%2C+Nick%3BMorfitt%2C+David%3BKalkuhl%2C+Arno%3BStaedtler%2C+Frank%3BLawton%2C+Michael&rft.aulast=Waring&rft.aufirst=Jeffrey&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=439&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; DOSE RESPONSE PROFILES; DNA; HEPATOTOXICITY ER - TY - JOUR T1 - Endocrine-Disrupting Effects of Cattle Feedlot Effluents on an Aquatic Sentinel Species, the Fathead Minnow AN - 14692606; 10659252 AB - Adult fathead minnows Pimephales promelas living up- and downstream of cattle feedlots in Nebraska were examined to assess possible endocrine-disrupting effects of feedlot runoff. The study was conducted at two affected sites confluent with the Elkhorn River, one directly below the effluent outfall of a feedlot and another receiving runoff from fields with dispersed cattle and agricultural activity. In vitro gonadal synthesis of sex steroid hormones was examined in both male and female fish, and bioassays were conducted for hormonal activity using water collected at the two contaminated sites and at reference sites. Results showed that fish collected below the feedlot exhibited altered reproductive biology, including decreased T synthesis, altered head morphometrics, and smaller testis size in males and decreased estrogen:androgen ratios in females. Results from assays using cells transfected with human androgen receptor revealed potent androgenic responses from the feedlot effluent. While androgenic activity was demonstrated clearly in water below the feedlot, the causal agents were not identified. JF - Environmental Health Perspectives AU - Orlando, Edward F AU - Kolok, Alan S AU - Binzcik, Gerry A AU - Gates, Jennifer L AU - Horton, Megan K AU - Lambright, Christy S AU - Gray, LEarl Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 353 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - LIVESTOCK FEEDLOT RUNOFF KW - PATHOLOGY, FISH KW - HORMONAL EFFECTS KW - BIOASSAY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Endocrine-Disrupting+Effects+of+Cattle+Feedlot+Effluents+on+an+Aquatic+Sentinel+Species%2C+the+Fathead+Minnow&rft.au=Orlando%2C+Edward+F%3BKolok%2C+Alan+S%3BBinzcik%2C+Gerry+A%3BGates%2C+Jennifer+L%3BHorton%2C+Megan+K%3BLambright%2C+Christy+S%3BGray%2C+LEarl&rft.aulast=Orlando&rft.aufirst=Edward&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - LIVESTOCK FEEDLOT RUNOFF; PATHOLOGY, FISH; HORMONAL EFFECTS; BIOASSAY ER - TY - JOUR T1 - Ambient Particulate Air Pollution, Heart Rate Variability, and Blood Markers of Inflammation in a Panel of Elderly Subjects AN - 14692523; 10659250 AB - Panels of elderly residents of three communities in Utah were recruited to participate in a study of the influence of ambient particulate air pollution on heart rate variability and blood markers of inflammation. Daily temperature, relative humidity, and airborne PM sub(2.5) data were collected, and repeated ambulatory electrocardiograph (ECG) monitoring was conducted during periods of both low and high air pollution. Immediately after each ECG monitoring period, blood samples were collected and analyzed. Reasonably consistent and statistically robust negative associations between PM sub(2.5) and measures of heart rate variability were observed. The levels of PM sub(2.5) were associated significantly with C-reactive protein in blood, but not with changes in white blood cell counts, red blood cells, platelets, or whole-blood viscosity. JF - Environmental Health Perspectives AU - Pope, CArden AU - Hansen, Matthew L AU - Long, Russell W AU - Nielsen, Karen R AU - Eatough, Norman L AU - Wilson, William E AU - Eatough, Delbert J Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 339 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - BLOOD ANALYSIS KW - CARDIOVASCULAR EFFECTS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Ambient+Particulate+Air+Pollution%2C+Heart+Rate+Variability%2C+and+Blood+Markers+of+Inflammation+in+a+Panel+of+Elderly+Subjects&rft.au=Pope%2C+CArden%3BHansen%2C+Matthew+L%3BLong%2C+Russell+W%3BNielsen%2C+Karen+R%3BEatough%2C+Norman+L%3BWilson%2C+William+E%3BEatough%2C+Delbert+J&rft.aulast=Pope&rft.aufirst=CArden&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=339&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 10 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; AIR POLLUTION EFFECTS; CARDIOVASCULAR EFFECTS; PARTICULATES ER - TY - JOUR T1 - The Asbestos Cancer Epidemic AN - 14692454; 10659241 AB - Asbestos, which is found in more than 3000 manufactured products, is one of the most pervasive environmental hazards in the world. Acute exposure can result in asbestosis, lung cancer, and mesothelioma. The inability of WHO and the International Labor Organization to address the problem of asbestos exposure is discussed, which is attributed to gross underfunding and to their attempts to placate industry while compromising on their mission to protect public health and the health and safety of workers, especially in developing nations. JF - Environmental Health Perspectives AU - LaDou, Joseph Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 285 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - WORLD HEALTH ORGANIZATION KW - PUBLIC HEALTH KW - ASBESTOS KW - HEALTH SAFETY, OCCUPATIONAL KW - ENV ACTION, INTERNATIONAL KW - ASBESTOSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692454?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Asbestos+Cancer+Epidemic&rft.au=LaDou%2C+Joseph&rft.aulast=LaDou&rft.aufirst=Joseph&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=285&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; HEALTH SAFETY, OCCUPATIONAL; WORLD HEALTH ORGANIZATION; ENV ACTION, INTERNATIONAL; PUBLIC HEALTH; ASBESTOS; ASBESTOSIS ER - TY - JOUR T1 - Annotation and Cross-Indexing of Array Elements on Multiple Platforms AN - 14692351; 10659594 AB - Associating a given nucleic acid sequence with the most current and consistent information on the gene of which it is part is complicated by the fact that the same sequence can be submitted to public databases from several sources that may assign different names and descriptions. An approach is presented for annotating microarray elements, which makes use of two public databases: UniGene and LocusLink. The approach allows one to map a given microarray element to a certain gene using UniGene and the GenBank accession number of the element, and to annotate that gene using LocusLink information. The algorithm used replaces frequently minimal sequence descriptions with biologically meaningful annotation. As illustration, results are presented from an application of the approach to compare results generated in the multi-laboratory genomics research program coordinated by the International Life Sciences Institute's Health and Environmental Sciences Institute Committee on the Application of Genomics to Mechanism-Based Risk Assessment. JF - Environmental Health Perspectives AU - Mattes, William B Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 506 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - DATA MANAGEMENT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Annotation+and+Cross-Indexing+of+Array+Elements+on+Multiple+Platforms&rft.au=Mattes%2C+William+B&rft.aulast=Mattes&rft.aufirst=William&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=506&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; DATA MANAGEMENT ER - TY - JOUR T1 - Identification of Platform-Independent Gene Expression Markers of Cisplatin Nephrotoxicity AN - 14692277; 10659592 AB - The cross-platform and cross-experiment reproducibility of gene changes induced in male SpragueDawley rat kidney by cisplatin treatment was compared. RNA prepared from the kidneys of rats on day 7 after a single injection of 5 mg/kg cisplatin was tested on three different cDNA-spotted arrays-the NIEHS custom rat cDNA array, the Incyte Rat Toxicology GEM, and the PHASE-1 Rat 700 array-and the high-density oligonucleotide Affymetrix RGU34A array. Results showed that a significant subset of the genes in the custom cDNA array set could be identified as differentially expressed on each of the other platforms, transcending specific target capture technologies. The same biology was captured and reported, independent of gene coverage, by different array formats when the gene profiles were developed that were linked to defined toxicities. JF - Environmental Health Perspectives AU - Thompson, Karol L AU - Afshari, Cynthia A AU - Amin, Rupesh P AU - Bertram, Timothy A AU - Car, Bruce AU - Cunningham, Michael AU - Kind, Clive Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 488 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - NEPHROTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692277?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Identification+of+Platform-Independent+Gene+Expression+Markers+of+Cisplatin+Nephrotoxicity&rft.au=Thompson%2C+Karol+L%3BAfshari%2C+Cynthia+A%3BAmin%2C+Rupesh+P%3BBertram%2C+Timothy+A%3BCar%2C+Bruce%3BCunningham%2C+Michael%3BKind%2C+Clive&rft.aulast=Thompson&rft.aufirst=Karol&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=488&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; NEPHROTOXICITY ER - TY - JOUR T1 - Toxicogenomics in Risk Assessment: an Overview of an HESI Collaborative Research Program AN - 14692244; 10659582 AB - In 1999, the International Life Sciences Institute Health and Environmental Sciences Institute (HESI) initiated a collaborative scientific program to address issues, challenges, and opportunities afforded by toxicogenomics. An overview is provided of the design and objectives of the experimental program in which the HESI Genomics Committee has conducted and analyzed toxicogenomics experiments within the broad fields of hepatotoxicity, nephrotoxicity, and genotoxicity. The experiences have highlighted the challenges inherent in the analysis and sharing of data sets generated by the different approaches. The committee has also partnered with the European Bioinformatics Institute to develop a database based on ArrayExpress database structure and Minimum Information About a Microarray Experiment data format standards. JF - Environmental Health Perspectives AU - Pennie, William AU - Pettit, Syril D AU - Lord, Peter G Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 417 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - GENETIC ENGINEERING KW - HEPATOTOXICITY KW - GENETICS, HUMAN KW - NEPHROTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14692244?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Toxicogenomics+in+Risk+Assessment%3A+an+Overview+of+an+HESI+Collaborative+Research+Program&rft.au=Pennie%2C+William%3BPettit%2C+Syril+D%3BLord%2C+Peter+G&rft.aulast=Pennie&rft.aufirst=William&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=417&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; GENETIC ENGINEERING; HEPATOTOXICITY; GENETICS, HUMAN; NEPHROTOXICITY ER - TY - JOUR T1 - In Utero Pesticide Exposure, Maternal Paraoxonase Activity, and Head Circumference AN - 14691641; 10659258 AB - In a cohort of infants delivered at Mount Sinai Hospital in New York City, the effects of in utero pesticide exposure on fetal growth and neurodevelopment were investigated. Questionnaires were administered to obtain information on pesticide and other environmental exposures, sociodemographic characteristics, maternal health, and lifestyle. Maternal blood samples were obtained during the third trimester, and cord blood samples were obtained at birth, and the samples were used to determine maternal and infant paraoxonase activity and polymorphisms. Standard clinical techniques were used to measure birth weight, length, and head circumference. No direct effects of pesticide exposure were found, based on questionnaire responses or pesticide metabolites, in terms of fetal growth or gestational age, but a small decrease in head circumference was noted when the levels of paraoxonase activity and the presence of 3,5,6-trichloro-2-pyridinol, a metabolite of chlorpyrifos, were considered. JF - Environmental Health Perspectives AU - Berkowitz, Gertrud S AU - Wetmur, James G AU - Birman-Deych, Elena AU - Obel, Josephine AU - Lapinski, Robert H AU - Godbold, James H AU - Holzman, Ian R Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 388 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - ENZYME ACTIVITY KW - REPRODUCTION, HUMAN KW - CHLORPYRIFOS KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=In+Utero+Pesticide+Exposure%2C+Maternal+Paraoxonase+Activity%2C+and+Head+Circumference&rft.au=Berkowitz%2C+Gertrud+S%3BWetmur%2C+James+G%3BBirman-Deych%2C+Elena%3BObel%2C+Josephine%3BLapinski%2C+Robert+H%3BGodbold%2C+James+H%3BHolzman%2C+Ian+R&rft.aulast=Berkowitz&rft.aufirst=Gertrud&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=388&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; ENZYME ACTIVITY; REPRODUCTION, HUMAN; CHLORPYRIFOS; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Cross-Site Comparison of Gene Expression Data Reveals High Similarity AN - 14691478; 10659587 AB - The Hepatotoxicity Working Group of the Health and Environmental Sciences Institute Committee on the Application of Genomics to Mechanism-Based Risk Assessment has investigated the mechanisms and markers of hepatotoxicity by comparing high-density gene expression data sets generated on two sets of RNA from two independent in vivo experiments in which male SpragueDawley rats were dosed with the known hepatotoxin, methapyrilene. The RNA samples were analyzed independently by seven different Affymetrix platform sites using RGU34A expression probe arrays containing 8799 probe sets interrogating primarily annotated genes. Methods are presented that were used to explore and quantitatively assess differences in the data. The interquartile range normalization was used on the data to achieve consistent ranges across the majority of the data and to preserve the phenomena of significant site variation. A universal reference sample was also used, along with a portion of the data considered to be invariant across arrays to generate a scoring function for normalization. A mixed-model approach is outlined, which provided a flexible method to adjust site effects and to use different array variations between sites. JF - Environmental Health Perspectives AU - Chu, Tzu-Ming AU - Deng, Shibing AU - Wolfinger, Russ AU - Paules, Richard S AU - Hamadeh, Hisham K Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 449 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - DATA MANAGEMENT KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691478?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cross-Site+Comparison+of+Gene+Expression+Data+Reveals+High+Similarity&rft.au=Chu%2C+Tzu-Ming%3BDeng%2C+Shibing%3BWolfinger%2C+Russ%3BPaules%2C+Richard+S%3BHamadeh%2C+Hisham+K&rft.aulast=Chu&rft.aufirst=Tzu-Ming&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=449&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; DATA MANAGEMENT; HEPATOTOXICITY ER - TY - JOUR T1 - Overview of an Interlaboratory Collaboration on Evaluating the Effects of Model Hepatotoxicants on Hepatic Gene Expression AN - 14691448; 10659584 AB - The use of genomic biomarkers to evaluate toxic effects is termed toxicogenomics, and to date, specific gene expression profiles have been evaluated for several types of toxicological studies. The Health and Environmental Sciences Institute of the International Life Sciences Institute formed a project committee to develop a collaborative scientific program to identify and address some of the issues, challenges, and opportunities encountered by the use of toxicogenomics in the context of risk assessment. One working group is the Hepatotoxicity Working Group, which has evaluated and compared biological, gene, and protein expression responses in rats exposed to well-studied hepatotoxins. Specifically, standard experimental protocols were developed for two prototypical hepatotoxicants: methapyrilene and clofibrate. An overview is provided of the interlaboratory study findings, which show that changes in mRNA levels for known transcriptional reporters of the compounds occurred, although there were discrepancies in some individual gene expression profiles. JF - Environmental Health Perspectives AU - Ulrich, Roger G AU - Rockett, John C AU - Gibson, GGordon AU - Pettit, Syril D Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 423 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - GENETICS, ANIMAL KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Overview+of+an+Interlaboratory+Collaboration+on+Evaluating+the+Effects+of+Model+Hepatotoxicants+on+Hepatic+Gene+Expression&rft.au=Ulrich%2C+Roger+G%3BRockett%2C+John+C%3BGibson%2C+GGordon%3BPettit%2C+Syril+D&rft.aulast=Ulrich&rft.aufirst=Roger&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=423&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; GENETICS, ANIMAL; HEPATOTOXICITY ER - TY - JOUR T1 - Mono(2-Ethyl-5-Hydroxyhexyl) Phthalate and Mono-(2-Ethyl-5-Oxohexyl) Phthalate as Biomarkers for Human Exposure Assessment to Di-(2-Ethylhexyl) Phthalate AN - 14691354; 10659248 AB - Paired urine and serum samples were collected from 176 US residents with no documented exposure to di-(2-ethylhexyl) phthalate (DEHP), and mono(2-ethylhexyl) phthalate (MEHP) and two oxidative metabolites, mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) and mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), were evaluated as markers for exposure to DEHP. While the concentrations of all three metabolites varied widely among the samples, concentrations of MEOHP and MEHHP in urine were approximately tenfold higher than those of MEHP. A good correlation was noted between urinary MEHP and MEHHP levels and between MEHP and MEOHP levels. Lower levels were found in the serum samples. The percentage of samples with detectable levels of free MEOHP and MEHHP in serum was much lower than that of total MEOHP and MEHHP. The findings suggested that MEOHP and MEHHP may be sensitive urinary markers of DEHP exposure. JF - Environmental Health Perspectives AU - Kato, Kayoko AU - Silva, Manori J AU - Reidy, John A AU - Hurtz, Donald AU - Malek, Nicole A AU - Needham, Larry L AU - Nakazawa, Hiroyuki Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 327 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - BIOLOGICAL INDICATORS KW - PHTHALIC ACID ESTERS KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691354?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Mono%282-Ethyl-5-Hydroxyhexyl%29+Phthalate+and+Mono-%282-Ethyl-5-Oxohexyl%29+Phthalate+as+Biomarkers+for+Human+Exposure+Assessment+to+Di-%282-Ethylhexyl%29+Phthalate&rft.au=Kato%2C+Kayoko%3BSilva%2C+Manori+J%3BReidy%2C+John+A%3BHurtz%2C+Donald%3BMalek%2C+Nicole+A%3BNeedham%2C+Larry+L%3BNakazawa%2C+Hiroyuki&rft.aulast=Kato&rft.aufirst=Kayoko&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=327&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; BIOLOGICAL INDICATORS; PHTHALIC ACID ESTERS; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - A Reassessment of the Nomenclature of Polychlorinated Biphenyl (PCB) Metabolites AN - 14691302; 10659242 AB - The metabolism and kinetics of PCB biotransformation depend on a number of factors, leading to two classes of metabolites-hydroxylated and methyl sulfone PCBs-that are present as contaminant residues in biota tissues. The full notation of the metabolites is inconvenient, so various shorthand notations have been developed and adopted. While the two classes of metabolites have related structures, different rules for abbreviations have emerged. Here, a standardized nomenclature is suggested for the naming of a PCB metabolite to compare congener-specific data among published studies. JF - Environmental Health Perspectives AU - Maervoet, Johan AU - Covaci, Adrian AU - Schepens, Paul AU - Sandau, Courtney D AU - Letcher, Robert J Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 291 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DATA, CHEMICAL KW - POLYCHLORINATED BIPHENYLS KW - METABOLIC ACTIVATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691302?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Reassessment+of+the+Nomenclature+of+Polychlorinated+Biphenyl+%28PCB%29+Metabolites&rft.au=Maervoet%2C+Johan%3BCovaci%2C+Adrian%3BSchepens%2C+Paul%3BSandau%2C+Courtney+D%3BLetcher%2C+Robert+J&rft.aulast=Maervoet&rft.aufirst=Johan&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=291&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DATA, CHEMICAL; POLYCHLORINATED BIPHENYLS; METABOLIC ACTIVATION ER - TY - JOUR T1 - Dye-Bias Correction in Dual-Labeled cDNA Microarray Gene Expression Measurements AN - 14691160; 10659591 AB - Dual-labeled microarray hybridization protocols can introduce a systematic dye-bias error that can confound identification of true biological effects that are distinct from technical artifact. While gene expression microarray data normalization corrects for systematic trends in dye incorporation and hybridization that affect all transcripts similarly, some transcripts behave differently from the global population. To demonstrate, accurately measure, and compensate for transcript-dependent dye bias, two split-control cDNA microarrays were dedicated for each set of eight hybridizations. Results showed that two-color directly labeled cDNA microarray hybridization protocols could systematically introduce dye-bias error. Removal of the variable dye bias was important to obtain a more accurate set of statistically significant microarray data. A mathematical dye-bias correction was used effectively to improve the standard deviations of technical replicate measurements, which had little effect on mean gene expression ratio values compared with more conventional replicate dye-swap approaches to mitigate dye bias. JF - Environmental Health Perspectives AU - Rosenzweig, Barry A AU - Pine, PScott AU - Domon, Olen E AU - Morris, Suzanne M AU - Chen, James J AU - Sistare, Frank D Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 480 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - GENETICS KW - DNA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Dye-Bias+Correction+in+Dual-Labeled+cDNA+Microarray+Gene+Expression+Measurements&rft.au=Rosenzweig%2C+Barry+A%3BPine%2C+PScott%3BDomon%2C+Olen+E%3BMorris%2C+Suzanne+M%3BChen%2C+James+J%3BSistare%2C+Frank+D&rft.aulast=Rosenzweig&rft.aufirst=Barry&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=480&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; GENETICS; DNA ER - TY - JOUR T1 - Identification of Putative Gene-Based Markers of Renal Toxicity AN - 14691096; 10659590 AB - Using male SpragueDawley rats, kidney gene expression profiles induced by three nephrotoxicants-cisplatin, gentamicin, and puromycin-were compared to identify patterns of gene expression that reflect different types of nephrotoxicity. Animals were exposed to the contaminants at different doses and for different periods of time, and after exposure, RNA was extracted and subjected to cDNA microarray hybridization and analysis, real-time quantitative polymerase chain reaction, and Western Blots. The microarray results were found to be consistent with numerous reports on the modulation in expression of various mRNA after renal injury. However, novel changes in the expression of genes were observed, which appeared to be associated with injury in specific portions of the nephron. JF - Environmental Health Perspectives AU - Amin, Rupesh P AU - Vickers, Alison E AU - Sistare, Frank AU - Thompson, Karol L AU - Roman, Richard J AU - Lawton, Michael AU - Kramer, Jeffrey Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 465 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - NEPHROTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Identification+of+Putative+Gene-Based+Markers+of+Renal+Toxicity&rft.au=Amin%2C+Rupesh+P%3BVickers%2C+Alison+E%3BSistare%2C+Frank%3BThompson%2C+Karol+L%3BRoman%2C+Richard+J%3BLawton%2C+Michael%3BKramer%2C+Jeffrey&rft.aulast=Amin&rft.aufirst=Rupesh&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=465&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; NEPHROTOXICITY ER - TY - JOUR T1 - Children's Exposure to Environmental Tobacco Smoke: Using Diverse Exposure Metrics to Document Ethnic/Racial Differences AN - 14690713; 10659259 AB - In a cohort of grade-school children in south Minneapolis, MN, exposure to environmental tobacco smoke (ETS) was studied via questionnaires about care-giver smoking status/behavior and timeactivity logs reporting the time and place of ETS exposure, and via two relatively expensive metrics: measurement of urinary total cotinine as an uptake marker of nicotine, and measurement of 4-(methylnitroamino)-1-(3-pyridyl)-1-butanol (NNAL) plus NNAL-Gluc-[4-(methylnitrosamino)-1-(3-pyridyl)-1-(O--D-glucopy- ranuronosyl)butane] as an uptake marker of the tobacco-specific lung carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. The markers were measured in urine samples collected in winter and spring. All four metrics suggested that a substantial fraction of elementary school-age children from the two economically disadvantaged and ethnically diverse neighborhoods was exposed routinely to ETS. The baseline questionnaire, timeactivity logs, and cotinine data indicated a consistent ethical/racial pattern for childhood ETS exposure, with African American children exposed to the greatest extent, followed by a category including Southeast Asians, whites, and Native Americans, and then by Hispanics, and Somali immigrants. Urinary cotinine did a reasonably good job of predicting NNAL + NNAL-Gluc. JF - Environmental Health Perspectives AU - Sexton, Ken AU - Adgate, John L AU - Church, Timothy R AU - Hecht, Stephen S AU - Ramachandran, Gurumurthy AU - Greaves, Ian A AU - Fredrickson, Ann L Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 392 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOLOGICAL INDICATORS KW - CIGARETTE SMOKE KW - NICOTINE KW - BIOACCUMULATION, HUMAN KW - RACIAL COMPARISONS KW - MINNESOTA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14690713?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Children%27s+Exposure+to+Environmental+Tobacco+Smoke%3A+Using+Diverse+Exposure+Metrics+to+Document+Ethnic%2FRacial+Differences&rft.au=Sexton%2C+Ken%3BAdgate%2C+John+L%3BChurch%2C+Timothy+R%3BHecht%2C+Stephen+S%3BRamachandran%2C+Gurumurthy%3BGreaves%2C+Ian+A%3BFredrickson%2C+Ann+L&rft.aulast=Sexton&rft.aufirst=Ken&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=392&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOLOGICAL INDICATORS; RACIAL COMPARISONS; CIGARETTE SMOKE; MINNESOTA; BIOACCUMULATION, HUMAN; NICOTINE ER - TY - JOUR T1 - Latex Allergy and Occupational Asthma in Health Care Workers: Adverse Outcomes AN - 14689805; 10659256 AB - Cases are presented of two patients who had developed severe latex allergy with dermatologic and respiratory symptoms. Both were nurses who had worked at the same community hospital. The two nurses also became sensitized to various chemicals and other environmental and food allergens. The symptoms of natural rubber latex allergy are outlined. In both cases, a history of clinical symptoms and positive skin-prick and radioallergosorbent tests confirmed the diagnosis of natural rubber latex allergy. JF - Environmental Health Perspectives AU - Amr, Sania AU - Bollinger, Mary E Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 378 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PATHOLOGY, HUMAN KW - RUBBER KW - HEALTH SAFETY, OCCUPATIONAL KW - HEALTH FACILITIES KW - ALLERGIES KW - ASTHMA KW - PROTECTIVE CLOTHING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Latex+Allergy+and+Occupational+Asthma+in+Health+Care+Workers%3A+Adverse+Outcomes&rft.au=Amr%2C+Sania%3BBollinger%2C+Mary+E&rft.aulast=Amr&rft.aufirst=Sania&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=378&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 41 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; HEALTH FACILITIES; PATHOLOGY, HUMAN; ALLERGIES; ASTHMA; PROTECTIVE CLOTHING; RUBBER ER - TY - JOUR T1 - Biologically Plausible Particulate Air Pollution Mortality ConcentrationResponse Functions AN - 14689685; 10659245 JF - Environmental Health Perspectives AU - Roberts, Steven Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 309 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - DOSE RESPONSE PROFILES KW - MORTALITY PATTERNS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biologically+Plausible+Particulate+Air+Pollution+Mortality+Concentration%26lt%3BND%26gt%3BResponse+Functions&rft.au=Roberts%2C+Steven&rft.aulast=Roberts&rft.aufirst=Steven&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=309&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; DOSE RESPONSE PROFILES; MORTALITY PATTERNS; PARTICULATES ER - TY - JOUR T1 - Database Development in Toxicogenomics: Issues and Efforts AN - 14689455; 10659593 AB - The field of toxicogenomics, which integrates the data-rich science of transcript profiling with traditional toxicological endpoint evaluation, has the potential to provide a better understanding of the relationship between gross toxicology and genome-level effects. Such study requires the incorporation of resources for bioinformatics, data management, and statistical analysis. The development of public toxicogenomics databases and the application of international database standards are discussed, noting the challenges in terms of accuracy and specificity, standardization of data inputs, and data quality and comparability. Several existing and emerging databases are identified and discussed, including: the European Bioinformatics Institute's ArrayExpress and Tox-MIAMExpress, the Chemical Effects in Biological Systems Knowledge Base, the Comparative Toxicogenomics Database, dbZach, ArrayTrack, and the EDGE database. JF - Environmental Health Perspectives AU - Mattes, William B AU - Pettit, Syril D AU - Sansone, Susanna-Assunta AU - Bushel, Pierre R AU - Waters, Michael D Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 495 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 4 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - DATA MANAGEMENT KW - TOXICOLOGY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689455?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Database+Development+in+Toxicogenomics%3A+Issues+and+Efforts&rft.au=Mattes%2C+William+B%3BPettit%2C+Syril+D%3BSansone%2C+Susanna-Assunta%3BBushel%2C+Pierre+R%3BWaters%2C+Michael+D&rft.aulast=Mattes&rft.aufirst=William&rft.date=2004-03-01&rft.volume=112&rft.issue=4&rft.spage=495&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; DATA MANAGEMENT; TOXICOLOGY ER - TY - JOUR T1 - Disparities in Cognitive Functioning by Race/Ethnicity in the Baltimore Memory Study AN - 14688791; 10659246 AB - The Baltimore Memory Study is a cohort study of the multilevel determinants of cognitive decline in Baltimore, MD, residents. Results are presented from an analysis of cross-sectional data from the first study visit to describe the extent and magnitude of the disparities across race/ethnic groups on a battery of neurobehavioral tests designed to assess a full range of cognitive abilities in adults. The target population consisted of 5070-yr-old residents of 65 contiguous neighborhoods who had lived within the region for the previous 5 yr. The neurobehavioral test battery is described. Results show that there were large differences in neurobehavioral test scores by race/ethnicity in all assessed cognitive domains, which declined by approximately 25% after adjusting for individual socioeconomic status and by another 10% after adjusting for additional individual factors related mainly to health and health-related behaviors, but large differences still persisted. Both male and female African-Americans scored lower than whites. JF - Environmental Health Perspectives AU - Schwartz, Brian S AU - Glass, Thomas A AU - Bolla, Karen I AU - Stewart, Walter F AU - Glass, Gregory AU - Rasmussen, Meghan AU - Bressler, Joseph Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 314 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 3 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SOCIOECONOMICS KW - MARYLAND KW - RACIAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14688791?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Disparities+in+Cognitive+Functioning+by+Race%2FEthnicity+in+the+Baltimore+Memory+Study&rft.au=Schwartz%2C+Brian+S%3BGlass%2C+Thomas+A%3BBolla%2C+Karen+I%3BStewart%2C+Walter+F%3BGlass%2C+Gregory%3BRasmussen%2C+Meghan%3BBressler%2C+Joseph&rft.aulast=Schwartz&rft.aufirst=Brian&rft.date=2004-03-01&rft.volume=112&rft.issue=3&rft.spage=314&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOCIOECONOMICS; MARYLAND; RACIAL COMPARISONS ER - TY - JOUR T1 - Monarchs in Australia: On the Winds of a Storm? AN - 1034827012; 17024067 AB - The monarch butterfly, Danaus plexippus, is one of Australia's best-known exotic butterflies, being first recorded here in the spring/summer of 1870/1871. However, the source of the original population is unknown. Using historical records we suggest that the most likely source of the founder population was from Vanuatu and/or New Caledonia. Many almost simultaneous 'first records' for the butterfly in Australia suggest that a large, well-distributed population was present when first noticed. While such a population may have developed from a limited number of individuals flying across the Coral Sea, the well documented, very dramatic appearance of large monarch populations in Australia does not appear to fit this model. Rather, we hypothesise that large numbers of monarchs were carried to Australia on cyclonic winds: no fewer that 3 cyclones hit the Queensland coast in early 1870. If one or more of these cyclones tracked from the Vanuatu/New Caledonia chain, then they may have transported monarchs. Once established on the central/northern Queensland coast, natural migration would account for the appearance of butterflies further south. JF - Biological Invasions AU - Clarke, Anthony R AU - Zalucki, Myron P AD - School of Natural Resource Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, 4001, Australia, a.Clarke@qut.edu.au Y1 - 2004/03// PY - 2004 DA - Mar 2004 SP - 123 EP - 127 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 6 IS - 1 SN - 1387-3547, 1387-3547 KW - Entomology Abstracts; Ecology Abstracts KW - Coasts KW - Cyclones KW - Danaus plexippus KW - Z 05310:Taxonomy, Morphology, Geography, and Fossils KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034827012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Invasions&rft.atitle=Monarchs+in+Australia%3A+On+the+Winds+of+a+Storm%3F&rft.au=Clarke%2C+Anthony+R%3BZalucki%2C+Myron+P&rft.aulast=Clarke&rft.aufirst=Anthony&rft.date=2004-03-01&rft.volume=6&rft.issue=1&rft.spage=123&rft.isbn=&rft.btitle=&rft.title=Biological+Invasions&rft.issn=13873547&rft_id=info:doi/10.1023%2FB%3ABINV.0000010120.29634.db LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Cyclones; Danaus plexippus DO - http://dx.doi.org/10.1023/B:BINV.0000010120.29634.db ER - TY - JOUR T1 - Residues in the distal heme pocket of neuroglobin. Implications for the multiple ligand binding steps. AN - 80154260; 14645216 AB - Amino acid residues in the ligand binding pocket of human neuroglobin have been identified by site-directed mutagenesis and their properties investigated by resonance Raman and flash photolysis methods. Wild-type neuroglobin has been shown to have six-coordinate heme in both ferric and ferrous states. Substitution of His96 by alanine leads to complete loss of heme, indicating that His96 is the proximal ligand. The resonance Raman spectra of M69L and K67T mutants were similar to those of wild-type (WT) neuroglobin in both ferric and ferrous states. By contrast, H64V was six-coordinate high-spin and five-coordinate high-spin in the ferric and ferrous states, respectively, at acidic pH. The spectra were pH-dependent and six-coordinate with the low-spin component dominating at alkaline pH. In a double mutant H64V/K67T, the high-spin component alone was detected in the both ferric and the ferrous states. This implies that His64 is the endogenous ligand and that Lys67 is situated nearby in the distal pocket. In the ferrous H64V and H64V/K67T mutants, the nu(Fe-His) stretching frequency appears at 221 cm(-1), which is similar to that of deoxymyoglobin. In the ferrous CO-bound state, the nu(Fe-CO) stretching frequency was detected at 521 and 494 cm(-1) in WT, M69L, and K67T, while only the 494 cm(-1) component was detected in the H64V and H64V/K67T mutants. Thus, the 521 cm(-1) component is attributed to the presence of polar His64. The CO binding kinetics were biphasic for WT, H64V, and K67T and monophasic for H64V/K67T. Thus, His64 and Lys67 comprise a unique distal heme pocket in neuroglobin. JF - The Journal of biological chemistry AU - Uno, Tadayuki AU - Ryu, Daisuke AU - Tsutsumi, Hiroko AU - Tomisugi, Yoshikazu AU - Ishikawa, Yoshinobu AU - Wilkinson, Anthony J AU - Sato, Hideaki AU - Hayashi, Takashi AD - Graduate School of Pharmaceutical Sciences, Kumamoto University, Oehonmachi, Kumamoto 862-0973, Japan. unot@gpo.kumamoto-u.ac.jp Y1 - 2004/02/13/ PY - 2004 DA - 2004 Feb 13 SP - 5886 EP - 5893 VL - 279 IS - 7 SN - 0021-9258, 0021-9258 KW - Ligands KW - 0 KW - Myoglobin KW - Nerve Tissue Proteins KW - deoxymyoglobin KW - neuroglobin KW - Heme KW - 42VZT0U6YR KW - Histidine KW - 4QD397987E KW - Carbon Monoxide KW - 7U1EE4V452 KW - Globins KW - 9004-22-2 KW - DNA KW - 9007-49-2 KW - Lysine KW - K3Z4F929H6 KW - Index Medicus KW - Lysine -- chemistry KW - Electrophoresis, Polyacrylamide Gel KW - Humans KW - Hydrogen-Ion Concentration KW - Amino Acid Sequence KW - Spectrum Analysis, Raman KW - Protein Binding KW - Binding Sites KW - Cloning, Molecular KW - Histidine -- chemistry KW - Base Sequence KW - Kinetics KW - Molecular Sequence Data KW - DNA -- chemistry KW - Spectrophotometry KW - Models, Chemical KW - Sequence Homology, Amino Acid KW - Protein Structure, Tertiary KW - Time Factors KW - Mutation KW - Myoglobin -- chemistry KW - Heme -- chemistry KW - Myoglobin -- analogs & derivatives KW - Nerve Tissue Proteins -- chemistry KW - Globins -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/80154260?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+biological+chemistry&rft.atitle=Residues+in+the+distal+heme+pocket+of+neuroglobin.+Implications+for+the+multiple+ligand+binding+steps.&rft.au=Uno%2C+Tadayuki%3BRyu%2C+Daisuke%3BTsutsumi%2C+Hiroko%3BTomisugi%2C+Yoshikazu%3BIshikawa%2C+Yoshinobu%3BWilkinson%2C+Anthony+J%3BSato%2C+Hideaki%3BHayashi%2C+Takashi&rft.aulast=Uno&rft.aufirst=Tadayuki&rft.date=2004-02-13&rft.volume=279&rft.issue=7&rft.spage=5886&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+biological+chemistry&rft.issn=00219258&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-03-30 N1 - Date created - 2004-02-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A model of neutralization of Chlamydia trachomatis based on antibody and host cell aggregation on the elementary body surface AN - 19218129; 5784879 AB - Humoral immunity is that aspect of specific immunity that is mediated by B lymphocytes and involves the neutralizing of pathogens by means of antibodies attaching to the pathogen's binding sites. Antibodies bind to and block ligand sites on the pathogen which prevents these sites from attaching to target cell receptors and so cell entry is inhibited. Many studies investigate the role of humoral immunity for protection against chlamydial challenge and they have shown that neutralization of the chlamydial body requires a large number of attached antibodies. Steric hindrance greatly influences the number of available sites that may be bound, reducing relative occupancy well below 100%. We model steric effects of antibody Fab fragment attachment indicating that they must be taken into consideration to accurately model valency, the number of available binding sites. We derive a partial differential equation for the number of antibody Fabs and host cell receptors that are aggregated to extracellular chlamydial elementary bodies. We consider steric effects in describing the size distribution of aggregates. Our theory is in good agreement with Monte Carlo simulations of binding. We use our theoretical prediction for the valency in a model for the in-host population dynamics of a chlamydial infection and we fit our model to experimental data. JF - Journal of Theoretical Biology AU - Wilson, D P AU - McElwain, DLS AD - School of Mathematical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Qld 4001, Australia, d.wilson@fsc.qut.edu.au Y1 - 2004/02/07/ PY - 2004 DA - 2004 Feb 07 SP - 321 EP - 330 PB - Elsevier Ltd VL - 226 IS - 3 SN - 0022-5193, 0022-5193 KW - Microbiology Abstracts B: Bacteriology KW - Cell surface KW - Mathematical models KW - Cell aggregation KW - Chlamydia trachomatis KW - Immune response (humoral) KW - Neutralization KW - J 02833:Immune response and immune mechanisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19218129?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Theoretical+Biology&rft.atitle=A+model+of+neutralization+of+Chlamydia+trachomatis+based+on+antibody+and+host+cell+aggregation+on+the+elementary+body+surface&rft.au=Wilson%2C+D+P%3BMcElwain%2C+DLS&rft.aulast=Wilson&rft.aufirst=D&rft.date=2004-02-07&rft.volume=226&rft.issue=3&rft.spage=321&rft.isbn=&rft.btitle=&rft.title=Journal+of+Theoretical+Biology&rft.issn=00225193&rft_id=info:doi/10.1016%2Fj.jtbi.2003.09.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Chlamydia trachomatis; Neutralization; Immune response (humoral); Mathematical models; Cell surface; Cell aggregation DO - http://dx.doi.org/10.1016/j.jtbi.2003.09.010 ER - TY - GEN T1 - North Korea's Nuclear Weapons: How Soon an Arsenal? AN - 1679114680; WM00599 AB - Reviews efforts to assess North Korea's nuclear weapons program, including technological achievements, condition of nuclear facilities, and nuclear fuel production; concludes North Korea is likely to have one or two nuclear weapons with more in production. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2004 SP - 6 KW - Arms control verification KW - Ballistic missiles KW - Fissile materials production KW - Korea (North) nuclear program KW - Nuclear monitoring KW - Nuclear reactors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679114680?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_wm&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=North+Korea%27s+Nuclear+Weapons%3A+How+Soon+an+Arsenal%3F&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2004-02-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - International Atomic Energy Agency; United States. Central Intelligence Agency N1 - Analyte descriptor - NSA document type: Report N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - Voxel-based computational models of real human anatomy: a review. AN - 80132439; 14730450 AB - Computational models of human anatomy are mathematical representations of human anatomy designed to be used in dosimetry calculations. They have been used in dosimetry calculations for radiography, radiotherapy, nuclear medicine, radiation protection and to investigate the effects of low frequency electromagnetic fields. Tomographic medical imaging techniques have allowed the construction of digital three-dimensional computational models based on the actual anatomy of individual humans. These are called voxel models, tomographic models or phantoms. Their usefulness lies in their faithful representation of human anatomy and the flexibility they afford by being able to be scaled in size to match the required human dimensions. Segmenting medical images in order to make voxel models is very time-consuming so semi-automatic segmentation techniques are being developed. Some 21 whole or partial body models currently exist and more are being prepared. These models are listed and discussed. JF - Radiation and environmental biophysics AU - Caon, Martin AD - School of Nursing and Midwifery, Sturt Building, Flinders University, GPO Box 2100, 5001, Adelaide, South Australia, Australia. martin.caon@flinders.edu.au Y1 - 2004/02// PY - 2004 DA - February 2004 SP - 229 EP - 235 VL - 42 IS - 4 SN - 0301-634X, 0301-634X KW - Index Medicus KW - Radiotherapy Planning, Computer-Assisted KW - Radiation Dosage KW - Nuclear Medicine KW - Humans KW - Adult KW - Tomography KW - Child KW - Male KW - Female KW - Anatomy, Cross-Sectional KW - Computer Simulation KW - Models, Biological KW - Models, Anatomic UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/80132439?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiation+and+environmental+biophysics&rft.atitle=Voxel-based+computational+models+of+real+human+anatomy%3A+a+review.&rft.au=Caon%2C+Martin&rft.aulast=Caon&rft.aufirst=Martin&rft.date=2004-02-01&rft.volume=42&rft.issue=4&rft.spage=229&rft.isbn=&rft.btitle=&rft.title=Radiation+and+environmental+biophysics&rft.issn=0301634X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-09-22 N1 - Date created - 2004-02-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Latex allergy: separating fact from fiction. AN - 71863156; 15104405 JF - Nursing AU - Lenehan, Gail Pisarcik AD - Massachusetts Nurses Association Congress on Occupational Health and Safety, Boston, USA. Y1 - 2004/02// PY - 2004 DA - February 2004 SP - 12 EP - 7; quiz 17-8 VL - Suppl SN - 0360-4039, 0360-4039 KW - Nursing KW - United States KW - Adaptation, Psychological KW - Risk Factors KW - Humans KW - Education, Nursing, Continuing KW - Practice Guidelines as Topic KW - Latex Hypersensitivity -- etiology KW - Dermatitis, Occupational -- etiology KW - Dermatitis, Allergic Contact -- etiology KW - Nursing Staff -- standards KW - Dermatitis, Occupational -- nursing KW - Gloves, Surgical -- adverse effects KW - Latex Hypersensitivity -- nursing KW - Dermatitis, Allergic Contact -- nursing KW - Nursing Staff -- education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71863156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nursing&rft.atitle=Latex+allergy%3A+separating+fact+from+fiction.&rft.au=Lenehan%2C+Gail+Pisarcik&rft.aulast=Lenehan&rft.aufirst=Gail&rft.date=2004-02-01&rft.volume=Suppl&rft.issue=&rft.spage=12&rft.isbn=&rft.btitle=&rft.title=Nursing&rft.issn=03604039&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-13 N1 - Date created - 2004-04-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - State Crime: The North Korean Drug Trade AN - 60694208; 200519267 AB - At least 50 documented incidents in more than 20 countries around the world, many involving arrest or detention of North Korean diplomats, link North Korea to drug trafficking. Such events, in the context of ongoing, credible, but unproven, allegations of large-scale state sponsorship of drug production & trafficking (especially heroin & methamphetamines), raise important issues for the global community in combating international drug trafficking. Rather than simply the activities of mercenary & corrupt individuals within the North Korean elite, the trafficking appears to be the result of a strategy initiated at the highest levels, directed through the shadowy organization known as Bureau 39. As the DPRK's drug trade becomes increasingly entrenched, & arguably decentralized, analysts question whether the Pyongyang regime (or any subsequent government) would have the ability to restrain such activity, should it so desire. 21 References. Adapted from the source document. JF - Global Crime AU - Perl, Raphael F AD - Foreign Affairs/Defense/Trade Division, US Congressional Research Service Y1 - 2004/02// PY - 2004 DA - February 2004 SP - 117 EP - 128 VL - 6 IS - 1 SN - 17744-0572, 17744-0572 KW - International Law KW - World Problems KW - Civil Service KW - Diplomacy KW - Organized Crime KW - North Korea KW - Drug Trafficking KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60694208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+Crime&rft.atitle=State+Crime%3A+The+North+Korean+Drug+Trade&rft.au=Perl%2C+Raphael+F&rft.aulast=Perl&rft.aufirst=Raphael&rft.date=2004-02-01&rft.volume=6&rft.issue=1&rft.spage=117&rft.isbn=&rft.btitle=&rft.title=Global+Crime&rft.issn=177440572&rft_id=info:doi/10.1080%2F1744057042000297016 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 21 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - North Korea; Diplomacy; Drug Trafficking; Civil Service; Organized Crime; World Problems; International Law DO - http://dx.doi.org/10.1080/1744057042000297016 ER - TY - JOUR T1 - The acute effects of olive oil v. cream on postprandial thermogenesis and substrate oxidation in postmenopausal women AN - 20237246; 8816740 AB - The influence of the source of dietary fat on postprandial thermogenesis and substrate oxidation rates, was examined in twelve postmenopausal women aged 57-73 years, with BMI 21.9-38.3 kg/m2. A single blind, randomised, paired comparison of two high-fat, isoenergetic, mixed test meals was conducted. The major source of fat was either cream (CREAM) or extra virgin olive oil (EVOO). RMR, diet-induced thermogenesis (DIT) and substrate oxidation rates over 5 h were measured by indirect calorimetry. There were no differences in body weight, RMR, fasting carbohydrate or fat oxidation rates between the two occasions. DIT (EVOO 97 (sd 46) v. CREAM 76 (sd 69) kJ/5 h and EVOO 5.2 (sd 2.5) v. CREAM 4.1 (sd 3.7)% energy) did not differ between the two test meals. The postprandial increase in carbohydrate oxidation rates, relative to their respective fasting values ( Delta COX), was significantly lower following the EVOO meal (EVOO 10.6 (sd 8.3) v. CREAM 17.5 (sd 10) g/5 h; paired t test, P=0.023), while postprandial fat oxidation rates ( Delta FOX) were significantly higher (EVOO 0.0 (sd 4.4) v. CREAM -3.6 (sd 4.0) g/5 h; P=0.028). In the eight obese subjects, however, DIT was significantly higher following the EVOO meal (EVOO 5.1 (sd 2.0) v. CREAM 2.5 (sd 2.9) %; P=0.01). This was accompanied by a significantly lower Delta COX (EVOO 10.9 (sd 9.9) v. CREAM 17.3 (sd 10.5) g/5 h; P=0.03) and significantly higher Delta FOX (EVOO 0.11 (sd 4.4) v. CREAM -4.1 (sd 4.5) g/5 h, P=0.034). The present study showed that olive oil significantly promoted postprandial fat oxidation and stimulated DIT in abdominally obese postmenopausal women. JF - British Journal of Nutrition AU - Soares, MJ AU - Cummings, S J AU - Mamo, JCL AU - Kenrick, M AU - Piers, L S AD - Department of Nutrition, Dietetics and Food Science, School of Public Health, Curtin University of Technology, GPO Box U 1987, Perth WA 6845, Australia, m.soares@curtin.edu.au Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 245 EP - 252 PB - Cambridge University Press, Journals Department VL - 91 IS - 2 SN - 0007-1145, 0007-1145 KW - Toxicology Abstracts KW - Olea KW - Obesity KW - Fasting KW - Olive oil KW - Thermogenesis KW - Acute effects KW - Body weight KW - Post-menopause KW - Energy KW - Oxidation KW - Cream KW - Calorimetry KW - Carbohydrates KW - X 24320:Food Additives & Contaminants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20237246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=British+Journal+of+Nutrition&rft.atitle=The+acute+effects+of+olive+oil+v.+cream+on+postprandial+thermogenesis+and+substrate+oxidation+in+postmenopausal+women&rft.au=Soares%2C+MJ%3BCummings%2C+S+J%3BMamo%2C+JCL%3BKenrick%2C+M%3BPiers%2C+L+S&rft.aulast=Soares&rft.aufirst=MJ&rft.date=2004-02-01&rft.volume=91&rft.issue=2&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=British+Journal+of+Nutrition&rft.issn=00071145&rft_id=info:doi/10.1079%2FBJN20031047 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Acute effects; Obesity; Body weight; Post-menopause; Energy; Oxidation; Cream; Calorimetry; Fasting; Carbohydrates; Olive oil; Thermogenesis; Olea DO - http://dx.doi.org/10.1079/BJN20031047 ER - TY - JOUR T1 - Induction of immune tolerance to a transplantation carbohydrate antigen by gene therapy with autologous lymphocytes transduced with adenovirus containing the corresponding glycosyltransferase gene AN - 19270964; 5840279 AB - Induction of tolerance to transplantation carbohydrate antigens is of clinical significance in recipients of ABO-incompatible allografts, or of xenografts. The experimental animal model used for studying such tolerance was that of alpha 1,3galactosyltransferase ( alpha 1,3GT) knockout (KO) mice, which lacks the alpha -gal epitope (Gal alpha 1-3Gal beta 1-4GlcNAc-R) and which can produce the anti-Gal antibody against it. In contrast, wild-type (WT) mice synthesize the alpha -gal epitope and are immunotolerant to it. KO lymphocytes transduced in vitro with adenovirus containing the alpha 1,3GT gene (Ad alpha GT) express alpha -gal epitopes. Administration of such lymphocytes into KO mice resulted in tolerization of naive and memory anti-Gal B cells. Mice tolerized by Ad alpha GT transduced lymphocytes failed to produce anti-Gal following immunizations with pig kidney membranes (PKM) expressing multiple alpha -gal epitopes. This tolerance was perpetuated by transplanted syngeneic WT mouse hearts expressing alpha -gal epitopes. Transplanted WT hearts survived in the tolerized KO mice for at least 100 days, despite repeated PKM immunizations. Control mice receiving lymphocytes transduced with adenovirus lacking the alpha 1,3GT gene were not tolerized, but produced anti-Gal and rejected transplanted WT hearts. This study suggests that autologous lymphocytes transduced with adenovirus containing A or B transferase genes may induce a similar tolerance to blood group antigens in humans. JF - Gene Therapy AU - Ogawa, H AU - Yin, D-P AU - Galili, U AD - Department of Cardiovascular-Thoracic Surgery, Rush University, 1653 West Congress Parkway, Chicago, IL 60612, USA Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 292 EP - 301 VL - 11 IS - 3 SN - 0969-7128, 0969-7128 KW - knockout mice KW - glycosyltransferase KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Heart KW - Antigens KW - Transplantation KW - Gene therapy KW - Adenovirus KW - Carbohydrates KW - Immunological tolerance KW - W 30965:Miscellaneous, Reviews KW - W4 120:Genetic Engineering in Medicine KW - W3 33180:Gene based (protocols, clinical trials, and animal models) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19270964?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Gene+Therapy&rft.atitle=Induction+of+immune+tolerance+to+a+transplantation+carbohydrate+antigen+by+gene+therapy+with+autologous+lymphocytes+transduced+with+adenovirus+containing+the+corresponding+glycosyltransferase+gene&rft.au=Ogawa%2C+H%3BYin%2C+D-P%3BGalili%2C+U&rft.aulast=Ogawa&rft.aufirst=H&rft.date=2004-02-01&rft.volume=11&rft.issue=3&rft.spage=292&rft.isbn=&rft.btitle=&rft.title=Gene+Therapy&rft.issn=09697128&rft_id=info:doi/10.1038%2Fsj.gt.3302178 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Adenovirus; Immunological tolerance; Carbohydrates; Transplantation; Antigens; Gene therapy; Heart DO - http://dx.doi.org/10.1038/sj.gt.3302178 ER - TY - JOUR T1 - Persistence of DNA of Gaeumannomyces graminis var. tritici in soil as measured by a DNA-based assay AN - 19270029; 5828439 AB - There are an increasing number of assays available for fungal plant pathogens based on DNA technology. We have developed such an assay for Gaeumannomyces graminis var. tritici (Ggt) in soil, using slot-blot hybridisation. To ensure the validity of DNA-based soil assays for the fungus, it is important to determine the stability of Ggt DNA in soil. This study was undertaken to quantify the DNA degradation of dead Ggt in soil using a DNA-based assay. Mycelia were killed using various treatments, then DNA was extracted and estimated by a slot-blot hybridisation technique using the specific Ggt DNA probe, pG158. Mycelia were also killed using a fungicide (triadimefon) at a concentration of 150-250 mu g ml super(-1). The amount of detectable DNA of Ggt, killed using triadimefon, declined by 82-93%. Inoculum in the form of diseased wheat roots, artificially inoculated ryegrass seed, particulate soil organic matter and whole soil was killed using heat- treatment. The amount of detectable DNA of Ggt declined markedly (90%) in both heat-treated roots and inoculated ryegrass seeds, and declined by 50% in both treated soil and soil organic matter. The rate of DNA degradation of Ggt in soil varied with the type of inoculum. The amount of detectable DNA of Ggt in dead mycelia declined by 99.8% after 4 days of incubation in soil. No DNA was detected after 8 days of incubation. In contrast, Ggt DNA in live mycelia declined by 70% after 8 days of incubation and declined to 10% of original DNA level after 32 days. In ground ryegrass seed inoculum, DNA in both killed and live Ggt declined by 50% after 8 days. In diseased roots, DNA from both live and killed Ggt did not appear to decline over 16 days. Estimates of the amount of Ggt in the soil using a DNA-based assay reflect both live and dead populations of the fungus. The rate of breakdown of DNA of the dead fungus is very high and the presence of dead fungi in roots probably a rare event so the DNA from dead fungus probably contributes little to the total DNA level. JF - FEMS Microbiology Ecology AU - Herdina AU - Neate, S AU - Jabaji-Hare, S AU - Ophel-Keller, K AD - South Australian Research and Development Institute, Field Crops Pathology Unit, Plant Research Centre, Waite Precinct, GPO Box 397, Adelaide, SA 5001, Australia, herdina@saugov.sa.gov.au Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 143 EP - 152 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 47 IS - 2 SN - 0168-6496, 0168-6496 KW - triadimefon KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Gaeumannomyces graminis KW - Organic matter KW - Survival KW - Mycelia KW - Hybridization analysis KW - Soil KW - Fungicides KW - DNA KW - K 03095:Soil KW - A 01047:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19270029?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Microbiology+Ecology&rft.atitle=Persistence+of+DNA+of+Gaeumannomyces+graminis+var.+tritici+in+soil+as+measured+by+a+DNA-based+assay&rft.au=Herdina%3BNeate%2C+S%3BJabaji-Hare%2C+S%3BOphel-Keller%2C+K&rft.aulast=Herdina&rft.aufirst=&rft.date=2004-02-01&rft.volume=47&rft.issue=2&rft.spage=143&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Ecology&rft.issn=01686496&rft_id=info:doi/10.1016%2FS0168-6496%2803%2900255-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Gaeumannomyces graminis; Survival; DNA; Soil; Hybridization analysis; Mycelia; Fungicides; Organic matter DO - http://dx.doi.org/10.1016/S0168-6496(03)00255-1 ER - TY - JOUR T1 - Comparison of Mismatch Amplification Mutation Assay with DNA Sequencing for Characterization of Fluoroquinolone Resistance in Neisseria gonorrhoeae AN - 19261226; 5826595 AB - A mismatch amplification mutation assay (MAMA) was developed for identification of point mutations in quinolone resistance-determining region (QRDR) of gyrA at codons 91 and 95. MAMA PCR was used to detect mutations at codons 91 and 95 of gyrA in 117 Neisseria gonorrhoeae isolates (with ciprofloxacin MICs of 0.004 to >32 mu g/ml) from Bangladesh during 1997 to 2001. The QRDR regions of the gyrA genes from 31 randomly selected isolates were sequenced, and the results were compared with those of MAMA PCR. Using mismatch PCR, a mutation at Ser91 could be detected in all 27 (resistant and intermediate) isolates, and an Asp95-to-Gly95 mutation could be detected in all 15 isolates, as detected by sequencing. MAMA PCR offers a simple, inexpensive, rapid, and easier alternative for detection of point mutations in fluoroquinolone resistance in N. gonorrhoeae. JF - Journal of Clinical Microbiology AU - Sultan, Z AU - Nahar, S AU - Wretlind, B AU - Lindback, E AU - Rahman, M AD - Laboratory Sciences Division, ICDDR,B, GPO Box 128, Dhaka 1000, Bangladesh, motiur@icddrb.org Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 591 EP - 594 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 42 IS - 2 SN - 0095-1137, 0095-1137 KW - mismatch amplification mutation assay KW - Microbiology Abstracts B: Bacteriology KW - Ciprofloxacin KW - Fluoroquinolones KW - Drug resistance KW - Point mutation KW - Polymerase chain reaction KW - Neisseria meningitidis KW - Minimum inhibitory concentration KW - J 02814:Drug resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19261226?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Comparison+of+Mismatch+Amplification+Mutation+Assay+with+DNA+Sequencing+for+Characterization+of+Fluoroquinolone+Resistance+in+Neisseria+gonorrhoeae&rft.au=Sultan%2C+Z%3BNahar%2C+S%3BWretlind%2C+B%3BLindback%2C+E%3BRahman%2C+M&rft.aulast=Sultan&rft.aufirst=Z&rft.date=2004-02-01&rft.volume=42&rft.issue=2&rft.spage=591&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.42.2.591-594.2004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Neisseria meningitidis; Drug resistance; Polymerase chain reaction; Fluoroquinolones; Point mutation; Minimum inhibitory concentration; Ciprofloxacin DO - http://dx.doi.org/10.1128/JCM.42.2.591-594.2004 ER - TY - JOUR T1 - Impacts of Land Surface Model Complexity on a Regional Simulation of a Tropical Synoptic Event AN - 18056793; 5853462 AB - A multimode Chameleon Surface Model (CHASM) with different levels of complexity in parameterizing surface energy balance is coupled to a limited-area model (DARLAM) to investigate the impacts of complexity in land surface representations on the model simulation of a tropical synoptic event. A low pressure system is examined in two sets of numerical experiments to discuss the following. (i) Does land surface parameterization influence regional numerical weather simulations? (ii) Can the complexity of land surface schemes in numerical models be represented by parameter tuning? The model-simulated tracks of the low pressure center do not, overall, show large sensitivity to the different CHASM modes coupled to the limited-area model. However, the landing position of the system, as one measurement of the track difference, can be influenced by several degrees in latitude and about one degree in longitude. Some of the track differences are larger than the intrinsic numerical noise in the model estimated from two sets of random perturbation runs. In addition, the landing time of the low pressure system can differ by about 14 h. The differences in the model-simulated central pressure exceed the model intrinsic numerical noise and such variations consistent with the differences seen in simulated surface fluxes. Furthermore, different complexity in the land surface scheme can significantly affect the model rainfall and temperature simulations associated with the low center, with differences in rainfall up to 20 mm day-1 and in surface temperature up to 2 degree C. Explicitly representing surface resistance and bare ground evaporation components in CHASM produces the most significant impacts on the surface processes. Results from the second set of experiments, in which the CHASM modes are calibrated by parameter tuning, demonstrate that the effects of the physical processes represented by extra complexity in some CHASM modes cannot be substituted for by parameter tuning in simplified land surface schemes. JF - Journal of Hydrometeorology AU - Zhang, H AU - McGregor, J L AU - Henderson-Sellers, A AU - Katzfey, J J AD - Bureau of Meteorology Research Center, GPO Box 1289K, Melbourne, VIC 3001, Australia, hzhang@bom.gov.au Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 180 EP - 198 PB - American Meteorological Society VL - 5 IS - 1 SN - 1525-755X, 1525-755X KW - Water Resources Abstracts; Meteorological & Geoastrophysical Abstracts KW - M2 551.509:Weather Forecasting/Modification (551.509) KW - SW 0815:Precipitation KW - M2 551.52:Radiation and Temperature (551.52) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18056793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hydrometeorology&rft.atitle=Impacts+of+Land+Surface+Model+Complexity+on+a+Regional+Simulation+of+a+Tropical+Synoptic+Event&rft.au=Zhang%2C+H%3BMcGregor%2C+J+L%3BHenderson-Sellers%2C+A%3BKatzfey%2C+J+J&rft.aulast=Zhang&rft.aufirst=H&rft.date=2004-02-01&rft.volume=5&rft.issue=1&rft.spage=180&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hydrometeorology&rft.issn=1525755X&rft_id=info:doi/10.1175%2F1525-7541%282004%29005%280180%3AIOLSMC%292.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=1525-755X&volume=5&page=180 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1175/1525-7541(2004)005(0180:IOLSMC)2.0.CO;2 ER - TY - JOUR T1 - Measuring optical properties of an eye lens using magnetic resonance imaging AN - 17903135; 5858879 AB - We compare the focal lengths of porcine lenses measured optically and by using a novel MRI technique. The geometric properties of the lenses were also measured and compared. The MRI technique exploits the dependence of both the lens refractive index and relaxation rates on the local protein concentration. By measuring the refractive index and corresponding values of R2 (=1/T2) for samples of lens homogenates with different protein concentrations, the dependence of refractive index on R2 was determined empirically. R2 maps, constructed from monoexponential fits to multiecho images of a slice through the lens containing the optical axis, were converted to refractive index maps using this relationship. A simulated ray trace through the refractive index map provided an estimate of lens focal length that was compared to a direct optical measurement of focal length using a laser ray-tracing method. It was found that the mean focal lengths estimated from the two techniques agreed within experimental uncertainty. The refractive index profile along the optical axis was found to be well described by a simple function of the form N = n sub(0) + n sub(1) x r where r is the (normalized) lens radius. JF - Magnetic Resonance Imaging AU - Jones, CE AU - Pope, J M AD - School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Australia 4001, j.pope@qut.edu.au Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 211 EP - 220 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 22 IS - 2 SN - 0730-725X, 0730-725X KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Refractivity KW - Magnetic resonance imaging KW - Eye lens KW - W4 150:Medical Imaging KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17903135?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Magnetic+Resonance+Imaging&rft.atitle=Measuring+optical+properties+of+an+eye+lens+using+magnetic+resonance+imaging&rft.au=Jones%2C+CE%3BPope%2C+J+M&rft.aulast=Jones&rft.aufirst=CE&rft.date=2004-02-01&rft.volume=22&rft.issue=2&rft.spage=211&rft.isbn=&rft.btitle=&rft.title=Magnetic+Resonance+Imaging&rft.issn=0730725X&rft_id=info:doi/10.1016%2Fj.mri.2003.07.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eye lens; Magnetic resonance imaging; Refractivity DO - http://dx.doi.org/10.1016/j.mri.2003.07.005 ER - TY - JOUR T1 - The effect of scan acquisition plane on the perceived quality of T1 weighted three-dimensional MR reconstructions of bony knee anatomy AN - 17694209; 6048418 AB - The aim of this study was to determine whether the orientation of scan acquisition plane exerts a significant influence on the perceived quality of three-dimensional (3-D) reconstructed magnetic resonance (MR) images of human knee anatomy. Non-isotropic, T1 weighted, unilateral knee MR studies were performed on five healthy volunteer subjects using each of the three routine orthogonal scan planes. A commercially available reconstructive software package was employed to generate a 3-D image from data in each scan plane. The three 3-D images of each subject were subjectively reviewed by 11 medical specialists with access to the original 2-D data, who were asked to nominate which of the 3-D reconstructions they felt best conveyed true anatomy. The overall, observer nominated, first preferences for each of the scan planes from which the 3-D images were generated were: coronal (40% [14/55]), sagittal (34.5% [22/55]) and axial (25.5% [19/55]). There was however no statistical evidence of an association between the orientation of MR scan acquisition plane and the perceived quality of resultant 3-D reconstructed images (Wilcoxon signed rank test, P > 0.70). In conclusion, the findings of this study suggest that the orientation of non-isotropic MR scan acquisition plane plays no significant role in the perceived quality of resultant 3-D reconstructed images. Mean values of visual analogue scores recorded in assessing the image quality indicate that finer slices may be better utilised to improve the perceived value of subsequent 3-D reconstructions. JF - Radiography AU - Kurmis AU - Slavotinek, J P AU - Hearn, T C AD - School of Informatics and Engineering, Flinders University, GPO Box 2100, Adelaide, South Australia 5001, Australia, andrew_kurmis@hotmail.com Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 53 EP - 59 VL - 10 IS - 1 SN - 1078-8174, 1078-8174 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - W4 150:Medical Imaging KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17694209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiography&rft.atitle=The+effect+of+scan+acquisition+plane+on+the+perceived+quality+of+T1+weighted+three-dimensional+MR+reconstructions+of+bony+knee+anatomy&rft.au=Kurmis%3BSlavotinek%2C+J+P%3BHearn%2C+T+C&rft.aulast=Kurmis&rft.aufirst=&rft.date=2004-02-01&rft.volume=10&rft.issue=1&rft.spage=53&rft.isbn=&rft.btitle=&rft.title=Radiography&rft.issn=10788174&rft_id=info:doi/10.1016%2Fj.radi.2004.01.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-04-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.radi.2004.01.009 ER - TY - JOUR T1 - Children's Health and the Environment: Public Health Issues and Challenges for Risk Assessment AN - 14691395; 10656491 AB - Several reports are introduced from an International Life Sciences Institute Workshop on Risk Assessment and Children's Health. Considered are the historical development of child-protective risk assessment and children's unique vulnerability to environmental toxicants due to their lifestyle, metabolic pathways, and longer time to develop diseases initiated by early exposures. Risks to children at different ages are outlined, as are specific diseases and outcomes of known or suspected environmental origin, such as asthma, childhood cancer, neurodevelopmental disorders, and endocrine disruption. Critical issues are then identified for improved assessment of environmental health risks to children. JF - Environmental Health Perspectives AU - Landrigan, Philip J AU - Kimmel, Carole A AU - Correa, Adolfo AU - Eskenazi, Brenda Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 257 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - PATHOLOGY, CHILDREN KW - DISEASES AND DISORDERS KW - CHEMICAL CONTAMINATION KW - TOXICOLOGY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Children%27s+Health+and+the+Environment%3A+Public+Health+Issues+and+Challenges+for+Risk+Assessment&rft.au=Landrigan%2C+Philip+J%3BKimmel%2C+Carole+A%3BCorrea%2C+Adolfo%3BEskenazi%2C+Brenda&rft.aulast=Landrigan&rft.aufirst=Philip&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=257&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 156 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DISEASES AND DISORDERS; PATHOLOGY, CHILDREN; CHEMICAL CONTAMINATION; TOXICOLOGY ER - TY - JOUR T1 - Vanadyl Sulfate Inhibits NO Production via Threonine Phosphorylation of eNOS AN - 14690598; 10656484 AB - The isolated buffer-perfused lung model using male New Zealand white rabbits, isolated rat pulmonary artery rings, and cultured human pulmonary artery endothelial cells were used to investigate the effects of vanadyl sulfate on the phosphorylation of threonine residues of endothelial nitric oxide synthase (eNOS). In intact lungs and isolated pulmonary artery rings, vanadyl sulfate produced pulmonary artery constriction, which was attributed in part to the loss of vasodilator activity provided by endothelial NO. The vanadyl sulfate-induced NO inhibition was associated with increased threonine phosphorylation of eNOS. The protein kinase inhibitor, calphostin C, attenuated vanadyl sulfate-induced threonine phosphorylation and restored NO production in cultured human pulmonary artery endothelial cells. JF - Environmental Health Perspectives AU - Li, Zhuowei AU - Carter, Jacqueline D AU - Dailey, Lisa A AU - Huang, Yuh-Chin T Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 201 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CARDIOVASCULAR EFFECTS KW - VANADIUM KW - PULMONARY EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14690598?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Vanadyl+Sulfate+Inhibits+NO+Production+via+Threonine+Phosphorylation+of+eNOS&rft.au=Li%2C+Zhuowei%3BCarter%2C+Jacqueline+D%3BDailey%2C+Lisa+A%3BHuang%2C+Yuh-Chin+T&rft.aulast=Li&rft.aufirst=Zhuowei&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=201&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CARDIOVASCULAR EFFECTS; VANADIUM; PULMONARY EFFECTS ER - TY - JOUR T1 - Concentrations of Dialkyl Phosphate Metabolites of Organophosphorus Pesticides in the U.S. Population AN - 14690557; 10656483 AB - As part of the National Health and Nutrition Examination Survey, urine samples were collected in 1999 and 2000 from approximately 2000 people in the US general population and analyzed for the following dialkyl phosphate metabolites of organophosphorus pesticides: dimethylphosphate (DMP), diethylphosphate (DEP), dimethylthiophosphate (DMTP), diethylthiophosphate (DETP), dimethyldithiophosphate (DMDTP), and diethyldithiophosphate (DEDTP). The data were stratified by age, sex, and race/ethnicity. Geometric means, least-squares geometric means, and percentiles of urinary concentrations were calculated using SAS software. The extensive data are tabulated, showing that DEP was detected with the highest frequency in about 70% of the samples, but DMTP was detected in the highest concentrations. For all analytes, children aged 611 yr had higher concentrations. All metabolites were detected more frequently in Mexican Americans and non-Hispanic blacks than in non-Hispanic whites. Mexican-Americans had higher concentrations of DEP and DEDTP, while non-Hispanic blacks had higher concentrations of DMP and DETP. Concentrations of 2,5,6-trichloro-2-pyridinol, a selective metabolite of chlorpyrifos and chlorpyrifos-methyl, were correlated significantly with both DEP and DETP concentrations. JF - Environmental Health Perspectives AU - Barr, Dana B AU - Bravo, Roberto AU - Weerasekera, Gayanga AU - Caltabiano, Lisa M AU - Whitehead, Ralph D AU - Olsson, Anders O AU - Caudill, Samuel P Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 186 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ORGANOPHOSPHATE PESTICIDES KW - BIOLOGICAL INDICATORS KW - NATIONALITY COMPARISONS KW - PESTICIDE EXPOSURE KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14690557?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Concentrations+of+Dialkyl+Phosphate+Metabolites+of+Organophosphorus+Pesticides+in+the+U.S.+Population&rft.au=Barr%2C+Dana+B%3BBravo%2C+Roberto%3BWeerasekera%2C+Gayanga%3BCaltabiano%2C+Lisa+M%3BWhitehead%2C+Ralph+D%3BOlsson%2C+Anders+O%3BCaudill%2C+Samuel+P&rft.aulast=Barr&rft.aufirst=Dana&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=186&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ORGANOPHOSPHATE PESTICIDES; BIOLOGICAL INDICATORS; NATIONALITY COMPARISONS; AGE COMPARISONS; PESTICIDE EXPOSURE ER - TY - JOUR T1 - A Framework for Assessing Risks to Children from Exposure to Environmental Agents AN - 14689944; 10656490 JF - Environmental Health Perspectives AU - Daston, George AU - Faustman, Elaine AU - Ginsberg, Gary AU - Fenner-Crisp, Penny AU - Olin, Stephen AU - Sonawane, Babasaheb AU - Bruckner, James Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 238 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - PATHOLOGY, CHILDREN KW - CHEMICAL CONTAMINATION KW - TOXICOLOGY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689944?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Framework+for+Assessing+Risks+to+Children+from+Exposure+to+Environmental+Agents&rft.au=Daston%2C+George%3BFaustman%2C+Elaine%3BGinsberg%2C+Gary%3BFenner-Crisp%2C+Penny%3BOlin%2C+Stephen%3BSonawane%2C+Babasaheb%3BBruckner%2C+James&rft.aulast=Daston&rft.aufirst=George&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=238&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; PATHOLOGY, CHILDREN; CHEMICAL CONTAMINATION; TOXICOLOGY ER - TY - JOUR T1 - Agricultural Task and Exposure to Organophosphate Pesticides Among Farmworkers AN - 14689406; 10656477 JF - Environmental Health Perspectives AU - Coronado, Gloria D AU - Thompson, Beti AU - Strong, Larkin AU - Griffith, William C AU - Islas, Ilda Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 142 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - WASHINGTON STATE KW - AGRICULTURAL CHEMICALS KW - PESTICIDE APPLICATION KW - BIOACCUMULATION, HUMAN KW - HEALTH SAFETY, OCCUPATIONAL KW - ORGANOPHOSPHATE PESTICIDES KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689406?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Agricultural+Task+and+Exposure+to+Organophosphate+Pesticides+Among+Farmworkers&rft.au=Coronado%2C+Gloria+D%3BThompson%2C+Beti%3BStrong%2C+Larkin%3BGriffith%2C+William+C%3BIslas%2C+Ilda&rft.aulast=Coronado&rft.aufirst=Gloria&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=142&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; ORGANOPHOSPHATE PESTICIDES; WASHINGTON STATE; AGRICULTURAL CHEMICALS; PESTICIDE APPLICATION; PESTICIDE EXPOSURE; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - A High-Level Disinfection Standard for Land-Applied Sewage Sludges (Biosolids) AN - 14689367; 10656475 AB - An overview is provided of the risks posed by the land application of sewage sludge, looking at the levels of disinfection required to destroy different groups of pathogens found in sewage sludges. Pathogen regrowth is considered, which occurs because of the amounts of nutrient contained in such biosolids, along with the production of either endotoxins or exotoxins by most bacteria found in sewage sludge, which can cause severe illness or death. In addition, many chemical contaminants found in processed sludges can interact with pathogens to cause, facilitate, or exacerbate the disease process through allergic and nonallergic mechanisms. A recent poll that looked at the public's attitudes toward land application found that more than half of respondents desired a total ban on such practices, while a significant amount wanted a ban on land application until the practice is proven to be safe. Selected recommendations are proposed to address the immediate adverse and health and environmental effects associated with land application of sewage sludge. JF - Environmental Health Perspectives AU - Gattie, David K AU - Lewis, David L Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 126 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SOIL CONTAMINATION KW - PUBLIC HEALTH KW - ENV IMPACT ASSESSMENT KW - SLUDGE DISPOSAL KW - BIOLOGICAL CONTAMINATION KW - DISINFECTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+High-Level+Disinfection+Standard+for+Land-Applied+Sewage+Sludges+%28Biosolids%29&rft.au=Gattie%2C+David+K%3BLewis%2C+David+L&rft.aulast=Gattie&rft.aufirst=David&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=126&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOIL CONTAMINATION; PUBLIC HEALTH; SLUDGE DISPOSAL; BIOLOGICAL CONTAMINATION; DISINFECTION; ENV IMPACT ASSESSMENT ER - TY - JOUR T1 - Developmental Effects of Chlorpyrifos Extend Beyond Neurotoxicity: Critical Periods for Immediate and Delayed-Onset Effects on Cardiac and Hepatic Cell Signaling AN - 14689316; 10656481 AB - Timed-pregnant SpragueDawley rats were exposed to chlorpyrifos during different developmental windows, and effects on the adenylyl cyclase signaling cascade in the heart and liver were examined. The developmental windows were gestational days 912 and 1720 and postnatal days 14 and 1114. Results showed that developmental chlorpyrifos exposure elicited immediate and late-emerging alterations in adenylyl cyclase-mediated cell signaling in the heart and liver, extending the adverse effects of chlorpyrifos beyond neurotoxicity. Although the major effects emerged in adulthood, some acute effects were detected in the period immediately after exposure. With treatment on gestational days 912, there was a shift in the cardiac adenylyl cyclase isoform, evidenced by a preferential increase in the response to manganese as opposed to forskolin, and for the gestational days 1720 treatment window, adverse effects on hepatic signaling profiles emerged at chlorpyrifos doses above the threshold for systemic toxicity. The acute effects of chlorpyrifos on adenylyl cyclase signaling were poorly correlated with the subsequent emergence of major, sex-dependent, tissue-selective functional alterations. Superimposed on the heterologous changes in adenylyl cyclase signaling, specific alterations were found in the responses to glucagon and beta -adrenoceptor stimulation, which play critical roles in cardiovascular and metabolic homeostasis. JF - Environmental Health Perspectives AU - Meyer, Armando AU - Seidler, Frederic J AU - Slotkin, Theodore A Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 170 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CARDIOVASCULAR EFFECTS KW - CHLORPYRIFOS KW - HEPATOTOXICITY KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689316?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developmental+Effects+of+Chlorpyrifos+Extend+Beyond+Neurotoxicity%3A+Critical+Periods+for+Immediate+and+Delayed-Onset+Effects+on+Cardiac+and+Hepatic+Cell+Signaling&rft.au=Meyer%2C+Armando%3BSeidler%2C+Frederic+J%3BSlotkin%2C+Theodore+A&rft.aulast=Meyer&rft.aufirst=Armando&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=170&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CARDIOVASCULAR EFFECTS; CHLORPYRIFOS; HEPATOTOXICITY; AGE COMPARISONS ER - TY - JOUR T1 - Dichlorodiphenyldichloroethane Burden and Breast Cancer Risk: a Meta-Analysis of the Epidemiologic Evidence AN - 14689253; 10656485 JF - Environmental Health Perspectives AU - Lopez-Cervantes, Malaquias AU - Torres-Sanchez, Luisa AU - Tobias, Aurelio AU - Lopez-Carrillo, Lizbeth Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 207 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - DDE KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14689253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Dichlorodiphenyldichloroethane+Burden+and+Breast+Cancer+Risk%3A+a+Meta-Analysis+of+the+Epidemiologic+Evidence&rft.au=Lopez-Cervantes%2C+Malaquias%3BTorres-Sanchez%2C+Luisa%3BTobias%2C+Aurelio%3BLopez-Carrillo%2C+Lizbeth&rft.aulast=Lopez-Cervantes&rft.aufirst=Malaquias&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=207&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; DDE; LITERATURE SURVEYS ER - TY - JOUR T1 - Human Exposure Monitoring and Evaluation in the Arctic: the Importance of Understanding Exposures to the Development of Public Health Policy AN - 14688946; 10656474 JF - Environmental Health Perspectives AU - Suk, William A AU - Avakian, Maureen D AU - Carpenter, David AU - Groopman, John D AU - Scammell, Madeleine AU - Wild, Christopher P AU - Greenberg, Michael R Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 113 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PUBLIC HEALTH KW - ECONOMIC GROWTH, DIMINISHED KW - ENV PROBLEMS, GENERAL KW - BIOLOGICAL INDICATORS KW - DIET KW - PUBLIC PARTICIPATION KW - ARCTIC KW - MEDICAL SURVEILLANCE KW - INDIGENOUS PEOPLE KW - UNITED STATES KW - ATTITUDE SURVEYS KW - TEMPORAL COMPARISONS KW - NEW JERSEY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14688946?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Human+Exposure+Monitoring+and+Evaluation+in+the+Arctic%3A+the+Importance+of+Understanding+Exposures+to+the+Development+of+Public+Health+Policy&rft.au=Suk%2C+William+A%3BAvakian%2C+Maureen+D%3BCarpenter%2C+David%3BGroopman%2C+John+D%3BScammell%2C+Madeleine%3BWild%2C+Christopher+P%3BGreenberg%2C+Michael+R&rft.aulast=Suk&rft.aufirst=William&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOLOGICAL INDICATORS; PUBLIC HEALTH; DIET; PUBLIC PARTICIPATION; ECONOMIC GROWTH, DIMINISHED; ARCTIC; MEDICAL SURVEILLANCE; INDIGENOUS PEOPLE; UNITED STATES; ATTITUDE SURVEYS; ENV PROBLEMS, GENERAL; NEW JERSEY; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Developmental Exposure to Chlorpyrifos Elicits Sex-Selective Alterations of Serotonergic Synaptic Function in Adulthood: Critical Periods and Regional Selectivity for Effects on the Serotonin Transporter, Receptor Subtypes, and Cell Signaling AN - 14688220; 10656478 AB - Using timed-pregnant SpragueDawley rats, the effects of developmental chlorpyrifos exposure on serotonin (5HT) synaptic function in adults were studied. Four different treatment windows were evaluated ranging from the neural tube stage and the late gestational period through postnatal phases of terminal neuronal differentiation and synaptogenesis. When the rats reached adulthood, factors were examined that are critical to the functioning of 5HT synaptases: the presynaptic 5HT transporter (5HTT) and the ability of 5HT receptors to control signaling through adenylyl cyclase. Results showed perturbations of 5HT synaptic components and 5HT-mediated responses in adult rats after chlorpyrifos exposure in development windows ranging from the neural tube stage through the second postnatal week, and the effects were noted even at exposures below the threshold for any signs of maternal, fetal, or neonatal toxicity. There was an enhancement of 5HT receptor expression, with peak effects elicited in the late gestational to early postnatal period, and preferential effects in males. Biphasic alterations were also found in the 5HTT site: promotional effects elicited by gestational exposure but inhibition in regions containing 5HT terminal zones when exposure was shifted to the post natal period. The greatest long-term alterations appeared to be concentrated in the late gestational to early postnatal period. JF - Environmental Health Perspectives AU - Aldridge, Justin E AU - Seidler, Frederic J AU - Slotkin, Theodore A Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 148 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - CHLORPYRIFOS KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14688220?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developmental+Exposure+to+Chlorpyrifos+Elicits+Sex-Selective+Alterations+of+Serotonergic+Synaptic+Function+in+Adulthood%3A+Critical+Periods+and+Regional+Selectivity+for+Effects+on+the+Serotonin+Transporter%2C+Receptor+Subtypes%2C+and+Cell+Signaling&rft.au=Aldridge%2C+Justin+E%3BSeidler%2C+Frederic+J%3BSlotkin%2C+Theodore+A&rft.aulast=Aldridge&rft.aufirst=Justin&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=148&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 30 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; CHLORPYRIFOS; AGE COMPARISONS ER - TY - JOUR T1 - An Evaluation of the Environmental and Health Effects of Vehicle Exhaust Catalysts in the United Kingdom AN - 14688198; 10656476 AB - Using 1992 as the base case, which was the year before catalytic converters became compulsory for all new automobiles in the UK, an ex post evaluation was conducted of the health effects arising from the action of vehicle catalytic converters on pollutant levels in urban areas over the period 199398, and an ex ante evaluation was performed on the health benefits projected to 2005. A health risk assessment model was developed and applied, which estimated the reduction in emissions, the changes in the concentrations of primary pollutants in urban environments, and health effects. Results showed that the health effects avoided by the reduction in PM sub(10) dominated the valuation estimates, but the greatest benefit in terms of morbidity appeared to be associated with nitrogen dioxide reductions. While lead concentrations in roadside dust were reduced considerably due to a ban on leaded gasoline, the concentrations of platinum increased markedly following the implementation of catalytic converters, which will warrant further monitoring and study. JF - Environmental Health Perspectives AU - Hutchinson, Emma J AU - Pearson, Peter JG Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 132 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PLATINUM KW - PUBLIC HEALTH KW - CATALYTIC CONVERTERS KW - URBAN ATMOSPHERE KW - ENV IMPACT ASSESSMENT KW - RISK ASSESSMENT KW - MORTALITY PATTERNS KW - AUTOMOBILE EMISSION CONTROL KW - UNITED KINGDOM KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14688198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=An+Evaluation+of+the+Environmental+and+Health+Effects+of+Vehicle+Exhaust+Catalysts+in+the+United+Kingdom&rft.au=Hutchinson%2C+Emma+J%3BPearson%2C+Peter+JG&rft.aulast=Hutchinson&rft.aufirst=Emma&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=132&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; PLATINUM; PUBLIC HEALTH; MORTALITY PATTERNS; CATALYTIC CONVERTERS; AUTOMOBILE EMISSION CONTROL; URBAN ATMOSPHERE; TEMPORAL COMPARISONS; ENV IMPACT ASSESSMENT; UNITED KINGDOM ER - TY - JOUR T1 - Cause-Specific Mortality and the Extended Effects of Particulate Pollution and Temperature Exposure AN - 14686966; 10656482 AB - Distributed lag models were applied to black smoke and daily mortality in Dublin, Ireland, in the 40 d after exposure to assess the cumulative effects of particulate air pollution on daily mortality over an extended post-exposure period, and to address possible confounding by extended effects of cold temperatures, the effects of temperature were assessed over the same period. The air-pollution data were obtained at six residential monitoring stations. Daily counts of deaths were calculated for total nontrauma deaths for cardiovascular causes, respiratory causes, and other causes. The cumulative effects of temperature and particulate air pollution were analyzed simultaneously in a generalized additive model. Results showed that each 1 degree C increase in temperature was associated with a 0.4% increase in total nontrauma mortality on the same day, while each decrease of 1 degree C was associated with an increase of 2.5% over the next 40 d. Warm temperatures had an immediate effect on mortality, especially cardiovascular mortality, while cold temperatures had strong effects on both cardiovascular and respiratory mortality that persisted from days to weeks. Black smoke was associated with significantly increased numbers of total nontrauma deaths on the same and subsequent days. JF - Environmental Health Perspectives AU - Goodman, Patrick G AU - Dockery, Douglas W AU - Clancy, Luke Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 179 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CARDIOVASCULAR EFFECTS KW - SMOKE KW - RESPIRATORY DISORDERS KW - IRELAND KW - URBAN ATMOSPHERE KW - PARTICULATES KW - ATMOSPHERIC TEMPERATURE KW - MORTALITY PATTERNS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14686966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cause-Specific+Mortality+and+the+Extended+Effects+of+Particulate+Pollution+and+Temperature+Exposure&rft.au=Goodman%2C+Patrick+G%3BDockery%2C+Douglas+W%3BClancy%2C+Luke&rft.aulast=Goodman&rft.aufirst=Patrick&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 14 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; CARDIOVASCULAR EFFECTS; ATMOSPHERIC TEMPERATURE; RESPIRATORY DISORDERS; SMOKE; MORTALITY PATTERNS; IRELAND; PARTICULATES; URBAN ATMOSPHERE; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Potential Exposure to PCBs, DDT, and PBDEs from Sport-Caught Fish Consumption in Relation to Breast Cancer Risk in Wisconsin AN - 14686931; 10656479 AB - The relationship between self-reported sport-caught fish consumption and breast cancer risk was examined in Wisconsin. Telephone interviews were conducted to obtain information about all sport-caught fish consumption and breast cancer risk factors. A similar proportion of women with breast cancer reported recent sport-caught fish consumption compared to age-matched controls. Regression models for any recent sport-caught fish consumption showed that a positive association with breast cancer risk was limited to younger premenopausal women, as the interaction between menopausal status and recent Great Lakes sport-caught fish consumption was significant. JF - Environmental Health Perspectives AU - McElroy, Jane A AU - Kanarek, Marty S AU - Trentham-Dietz, Amy AU - Robert, Stephanie A AU - Hampton, John M AU - Newcomb, Polly A AU - Anderson, Henry A Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 156 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - FOOD CONSUMPTION PATTERNS KW - FISHING, SPORT KW - CANCER RISK KW - WISCONSIN KW - GREAT LAKES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14686931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Potential+Exposure+to+PCBs%2C+DDT%2C+and+PBDEs+from+Sport-Caught+Fish+Consumption+in+Relation+to+Breast+Cancer+Risk+in+Wisconsin&rft.au=McElroy%2C+Jane+A%3BKanarek%2C+Marty+S%3BTrentham-Dietz%2C+Amy%3BRobert%2C+Stephanie+A%3BHampton%2C+John+M%3BNewcomb%2C+Polly+A%3BAnderson%2C+Henry+A&rft.aulast=McElroy&rft.aufirst=Jane&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=156&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FOOD CONSUMPTION PATTERNS; CANCER RISK; FISHING, SPORT; WISCONSIN; GREAT LAKES ER - TY - JOUR T1 - Hazard Identification and Predictability of Children's Health Risk from Animal Data AN - 14686913; 10656492 AB - Because of physiological and behavioral differences, children and adults may differ in how they are affected by xenobiotic exposures. Here, an overview is provided of the status of hazard identification as it pertains to children's health. The critical periods and important milestones in development are highlighted, and the relevance of animal data to children's risk assessment is considered, focusing on the methods of extrapolating animal studies to assess potential hazards to children, the attributes of a successful animal model, and the handling of mechanistic data. JF - Environmental Health Perspectives AU - Morford, LaRonda L AU - Henck, Judith W AU - Breslin, William J AU - DeSesso, John M Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 266 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - SPECIES COMPARISONS KW - PATHOLOGY, CHILDREN KW - CHEMICAL CONTAMINATION KW - TOXICOLOGY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14686913?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Hazard+Identification+and+Predictability+of+Children%27s+Health+Risk+from+Animal+Data&rft.au=Morford%2C+LaRonda+L%3BHenck%2C+Judith+W%3BBreslin%2C+William+J%3BDeSesso%2C+John+M&rft.aulast=Morford&rft.aufirst=LaRonda&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=266&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; SPECIES COMPARISONS; PATHOLOGY, CHILDREN; CHEMICAL CONTAMINATION; TOXICOLOGY ER - TY - JOUR T1 - Highly Chlorinated PCBs Inhibit the Human Xenobiotic Response Mediated by the Steroid and Xenobiotic Receptor (SXR) AN - 14686878; 10656480 AB - The mammalian xenobiotic response is mediated primarily by two broad-specificity sensors: the human steroid and xenobiotic receptor (SXR)/rodent pregnane X receptor (PXR) and the constitutive androstane receptor. SXR/PXR is activated by a diverse group of steroid hormones, dietary compounds, prescription drugs, and xenobiotics, but SXR/PXR exhibits species-specific differences in its response. In this study, a variety of PCBs were tested to determine their ability to activated human and rodent SXR/PXR. Results showed that highly chlorinated PCB congeners were able to activate rodent PXR, but not human SXR, although the same PCBs were able to bind directly to human SXR and antagonize its activation and target gene induction in primary human hepatocytes and LS180 human colon carcinoma cells. A predictive molecular model was then developed and used to identify additional antagonistic PCBs, which identified PCBs that are among the most persistent and abundant congeners in human tissues and show striking differences in their potential to be metabolized in rodents and humans. JF - Environmental Health Perspectives AU - Tabb, Michelle M AU - Kholodovych, Vladyslav AU - Grun, Felix AU - Zhou, Changcheng AU - Welsh, William J AU - Blumberg, Bruce Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 163 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - SPECIES COMPARISONS KW - METABOLIC ACTIVATION KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14686878?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Highly+Chlorinated+PCBs+Inhibit+the+Human+Xenobiotic+Response+Mediated+by+the+Steroid+and+Xenobiotic+Receptor+%28SXR%29&rft.au=Tabb%2C+Michelle+M%3BKholodovych%2C+Vladyslav%3BGrun%2C+Felix%3BZhou%2C+Changcheng%3BWelsh%2C+William+J%3BBlumberg%2C+Bruce&rft.aulast=Tabb&rft.aufirst=Michelle&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; SPECIES COMPARISONS; METABOLIC ACTIVATION; RODENTS ER - TY - JOUR T1 - An Unexplained Case of Elevated Blood Lead in a Hispanic Child AN - 14686273; 10656487 JF - Environmental Health Perspectives AU - Lowry, Larry K AU - Cherry, Debra C AU - Brady, Charles F AU - Huggins, Barbara AU - D'Sa, Anita M AU - Levin, Jeffrey L Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 222 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - SOURCE MEASUREMENT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14686273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=An+Unexplained+Case+of+Elevated+Blood+Lead+in+a+Hispanic+Child&rft.au=Lowry%2C+Larry+K%3BCherry%2C+Debra+C%3BBrady%2C+Charles+F%3BHuggins%2C+Barbara%3BD%27Sa%2C+Anita+M%3BLevin%2C+Jeffrey+L&rft.aulast=Lowry&rft.aufirst=Larry&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=222&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD LEAD LEVEL; SOURCE MEASUREMENT ER - TY - JOUR T1 - Incorporating Children's Toxicokineteics into a Risk Framework AN - 14685488; 10656493 AB - While progress in toxicokinetics has removed some uncertainty in cross-species extrapolations in risk assessment for adults, the principles have yet to be applied in a systematic manner to risk assessment for children. Here, a framework is outlined for conducting children's toxicokinetic risk assessments, which involves three phases, each of which is considered in some detail: problem formulation; data analysis and development of a risk assessment approach, in which chemical-specific data regarding the fate of a chemical being analyzed are combined with children's data relating to the developmental profile of toxicokinetic systems; and risk characterization, in which the analytical results are placed in perspective, taking into consideration the degree of uncertainty and variability in the analysis. JF - Environmental Health Perspectives AU - Ginsberg, Gary AU - Slikker, William AU - Bruckner, James AU - Sonawane, Babasaheb Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 272 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - DOSIMETRY KW - PATHOLOGY, CHILDREN KW - CHEMICAL CONTAMINATION KW - TOXICOLOGY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14685488?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Incorporating+Children%27s+Toxicokineteics+into+a+Risk+Framework&rft.au=Ginsberg%2C+Gary%3BSlikker%2C+William%3BBruckner%2C+James%3BSonawane%2C+Babasaheb&rft.aulast=Ginsberg&rft.aufirst=Gary&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=272&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DOSIMETRY; PATHOLOGY, CHILDREN; CHEMICAL CONTAMINATION; TOXICOLOGY ER - TY - JOUR T1 - Assessing the Health Benefits of Air Pollution Reduction for Children AN - 14685443; 10656488 AB - To examine the impacts of criteria air pollutants on children, the peer-reviewed air-pollution literature was surveyed for studies focusing exclusively on children or presenting results for children in the US. To estimate the expected cases averted for each health effect considered due to the Clean Air Act, measures of risk were converted to an exposureresponse regression coefficient, and the analysis was estimated for a projected 2010 US population. Reductions in PM sub(10) in the year 2010 were estimated to lead to a median of 160 fewer expected cases of postneonatal mortality, 10,000 fewer respiratory hospitalizations in children aged 05 yr, and 1300 fewer emergency department visits in children 116 yr of age. Small reductions in ambient ozone concentrations led to 700 fewer respiratory hospitalizations in children aged 02 yr and 1600 fewer emergency department visits for asthma in children aged 116 yr. Reductions in carbon monoxide concentrations led to 9400 fewer asthma hospitalizations and 35,000 fewer emergency department visits in children aged 116 yr, and nitrogen dioxide reductions led to 2.2 million fewer school absences in children aged 910 yr. JF - Environmental Health Perspectives AU - Wong, Eva Y AU - Gohlke, Julia AU - Griffith, William C AU - Farrow, Scott AU - Faustman, Elaine M Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 226 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NITROGEN DIOXIDE KW - RESPIRATORY DISORDERS KW - CARBON MONOXIDE KW - PARTICULATES KW - OZONE KW - PATHOLOGY, CHILDREN KW - MORTALITY PATTERNS KW - AIR POLLUTION CONTROL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14685443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessing+the+Health+Benefits+of+Air+Pollution+Reduction+for+Children&rft.au=Wong%2C+Eva+Y%3BGohlke%2C+Julia%3BGriffith%2C+William+C%3BFarrow%2C+Scott%3BFaustman%2C+Elaine+M&rft.aulast=Wong&rft.aufirst=Eva&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=226&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NITROGEN DIOXIDE; PATHOLOGY, CHILDREN; CARBON MONOXIDE; RESPIRATORY DISORDERS; MORTALITY PATTERNS; OZONE; PARTICULATES; AIR POLLUTION CONTROL ER - TY - JOUR T1 - Effect of Succimer on Growth of Preschool Children with Moderate Blood Lead Levels AN - 14684372; 10656489 AB - The effect of succimer on height and weight growth of children with moderate blood lead levels was examined during and after administration of succimer or placebo within a 34-month period. The children were participants in the Treatment of Lead-Exposed Children trial. Results showed that the largest estimated difference in mean blood Pb level was noted one week after initiating the first round of treatment, followed by a partial rebound after successive rounds. Over time, the mean blood Pb level of succimer-treated children was 4.5 mu g/dl lower than that of placebo children during the six-month period after initiation of treatment, and 2.7 mu g/dl lower during the 12-month period after initiation of treatment. From 12 to 34 months, however, mean blood Pb levels did not differ significantly between groups. Succimer was associated with slower growth in height and weight in the first 34 months. JF - Environmental Health Perspectives AU - Peterson, Karen E AU - Salganik, Mikhail AU - Campbell, Carla AU - Rhoads, George G AU - Rubin, Judith AU - Berger, Omer AU - Ware, James H Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 233 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOMASS KW - BLOOD LEAD LEVEL KW - CHELATING AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14684372?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+of+Succimer+on+Growth+of+Preschool+Children+with+Moderate+Blood+Lead+Levels&rft.au=Peterson%2C+Karen+E%3BSalganik%2C+Mikhail%3BCampbell%2C+Carla%3BRhoads%2C+George+G%3BRubin%2C+Judith%3BBerger%2C+Omer%3BWare%2C+James+H&rft.aulast=Peterson&rft.aufirst=Karen&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=233&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOMASS; BLOOD LEAD LEVEL; CHELATING AGENTS ER - TY - JOUR T1 - Assessing Potential Risk of Heavy Metal Exposure from Consumption of Home-Produced Vegetables by Urban Populations AN - 14684338; 10656486 AB - The potential risk of heavy-metal exposure from the consumption of home-produced vegetables was explored at a large urban site located in West Midlands, UK. The uptake of cadmium, copper, nickel, lead, and zinc by a variety of vegetable crops was modeled using the soil characteristics most likely to control bioavailability and commonly reported in geochemical surveys and experimental data sets. The dietary data were adjusted according to the quantities consumed by three different population subgroups: the average person, the highly exposed person, and the highly exposed infant. Results are presented in the form of hazard index maps for each population subgroup, which show that the hazard estimates varied considerably with geochemical parameters, although most of the population had a hazard index of less than 1.0. JF - Environmental Health Perspectives AU - Hough, Rupert L AU - Breward, Neil AU - Young, Scott D AU - Crout, Neil MJ AU - Tye, Andrew M AU - Moir, Ann M AU - Thornton, Iain Y1 - 2004/02// PY - 2004 DA - Feb 2004 SP - 215 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 2 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - VEGETABLES KW - HEAVY METALS KW - FOOD CONTAMINATION KW - UNITED KINGDOM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14684338?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessing+Potential+Risk+of+Heavy+Metal+Exposure+from+Consumption+of+Home-Produced+Vegetables+by+Urban+Populations&rft.au=Hough%2C+Rupert+L%3BBreward%2C+Neil%3BYoung%2C+Scott+D%3BCrout%2C+Neil+MJ%3BTye%2C+Andrew+M%3BMoir%2C+Ann+M%3BThornton%2C+Iain&rft.aulast=Hough&rft.aufirst=Rupert&rft.date=2004-02-01&rft.volume=112&rft.issue=2&rft.spage=215&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t maps N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; VEGETABLES; HEAVY METALS; UNITED KINGDOM; FOOD CONTAMINATION ER - TY - JOUR T1 - Cholera AN - 17953093; 5885793 AB - Intestinal infection with Vibrio cholerae results in the loss of large volumes of watery stool, leading to severe and rapidly progressing dehydration and shock. Without adequate and appropriate rehydration therapy, severe cholera kills about half of affected individuals. Cholera toxin, a potent stimulator of adenylate cyclase, causes the intestine to secrete watery fluid rich in sodium, bicarbonate, and potassium, in volumes far exceeding the intestinal absorptive capacity. Cholera has spread from the indian subcontinent where it is endemic to involve nearly the whole world seven times during the past 185 years. V cholerae serogroup 01, biotype El Tor, has moved from Asia to cause pandemic disease in Africa and South America during the past 35 years. A new serogroup, 0139, appeared in south Asia in 1992, has become endemic there, and threatens to start the next pandemic. Research on case management of cholera led to the development of rehydration therapy for dehydrating diarrhoea in general, including the proper use of intravenous and oral rehydration solutions. Appropriate case management has reduced deaths from diarrhoeal disease by an estimated 3 million per year compared with 20 years ago. Vaccination was thought to have no role for cholera, but new oral vaccines are showing great promise. JF - Lancet AU - Sack, DA AU - Sack, R B AU - Nair, G B AU - Siddique, A K AD - ICDDR,B, GPO Box 128, Dhaka, Bangladesh, dsack@icddrb.org Y1 - 2004/01/17/ PY - 2004 DA - 2004 Jan 17 SP - 223 EP - 233 VL - 363 IS - 9404 SN - 0099-5355, 0099-5355 KW - Microbiology Abstracts B: Bacteriology KW - Vibrio cholerae KW - Diarrhea KW - Shock KW - Cholera toxin KW - Reviews KW - Cholera KW - Vaccination KW - Adenylate cyclase KW - Dehydration KW - J 02846:Gastrointestinal tract UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17953093?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet&rft.atitle=Cholera&rft.au=Sack%2C+DA%3BSack%2C+R+B%3BNair%2C+G+B%3BSiddique%2C+A+K&rft.aulast=Sack&rft.aufirst=DA&rft.date=2004-01-17&rft.volume=363&rft.issue=9404&rft.spage=223&rft.isbn=&rft.btitle=&rft.title=Lancet&rft.issn=00995355&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Vibrio cholerae; Reviews; Cholera; Diarrhea; Dehydration; Shock; Cholera toxin; Adenylate cyclase; Vaccination ER - TY - GEN T1 - [Negotiations with United Self-Defense Forces of Colombia] AN - 1679116210; CD02112 AB - Expresses concerns about Colombian government's negotiations with United Self-Defense Forces of Colombia paramilitaries, and requests clarification of U.S. views on negotiations. AU - United States. Congress. House AD - United States. Congress. House PY - 2004 SP - 3 KW - Powell, Colin L. KW - Amnesty KW - Human rights violations KW - Laws and regulations KW - Paramilitary forces KW - Uribe Vélez, Álvaro KW - Uribe Vélez, Álvaro UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679116210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_cd&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=%5BNegotiations+with+United+Self-Defense+Forces+of+Colombia%5D&rft.au=United+States.+Congress.+House&rft.aulast=United+States.+Congress.+House&rft.aufirst=&rft.date=2004-01-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - United Self-Defense Forces of Colombia N1 - Analyte descriptor - NSA document type: Letter N1 - People - Uribe Vélez, Álvaro N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - Safeguarding the Nation's Drinking Water: EPA and Congressional Actions AN - 14691531; 10659758 AB - Since September 11, 2001, EPA and its water sector partners have initiated a range of actions to enhance the security of US water supplies and infrastructure from terrorist or other threats. In emergency supplemental appropriations for FY2002, the 107th Congress provided EPA with about $90 million for drinking water security activities. The 107th Congress also passed the Public Health Security and Bioterrorism Preparedness and Response Act of 2002, which requires many community water systems to assess their vulnerabilities and prepare emergency preparedness and response plans. Oversight issues to be addressed by the 108th Congress include implementation of drinking water security provisions of the Bioterrorism Act, and coordination of EPA and US Department of Homeland Security water sector activities. JF - US Congressional Research Service Report RL31294 AU - Tiemann, Mary Y1 - 2004/01/12/ PY - 2004 DA - 2004 Jan 12 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - PRODUCT SAFETY KW - WATER SUPPLY KW - CONSUMER PROTECTION KW - EPA, FEDERAL KW - PUBLIC HEALTH KW - WATER RESOURCES MANAGEMENT KW - EMERGENCY PLANNING KW - LAW, FEDERAL KW - WATER, DRINKING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14691531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+RL31294&rft.atitle=Safeguarding+the+Nation%27s+Drinking+Water%3A+EPA+and+Congressional+Actions&rft.au=Tiemann%2C+Mary&rft.aulast=Tiemann&rft.aufirst=Mary&rft.date=2004-01-12&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+RL31294&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-07181.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PRODUCT SAFETY; WATER SUPPLY; CONSUMER PROTECTION; EPA, FEDERAL; WATER RESOURCES MANAGEMENT; PUBLIC HEALTH; EMERGENCY PLANNING; LAW, FEDERAL; WATER, DRINKING ER - TY - JOUR T1 - Substance P immunoreactive nerve fibres in the domestic chick ankle joint before and after acute urate arthritis. AN - 80076006; 14698445 AB - Substance P immunoreactive (SP-IR) nerve fibres were identified using fluorescence immunohistochemistry and the length of the labelled individual nerve fibres was measured using confocal microscopy of whole mounts of the lateral wall of the ankle joint in 2-week-old domestic chicks. In the normal ankle there was an extensive network of SP-IR fibres in the synovial and subsynovial tissue of the joint capsule. Fours hours after injection of sodium urate into the joint space the joint was inflamed and there was a significant reduction in the labelled nerve fibres. These results demonstrate experimentally that painful gouty arthritis produces a neurogenic depletion of substance P from peripheral nerve fibres in the synovial and subsynovial tissue. JF - Neuroscience letters AU - Lunam, C A AU - Gentle, M J AD - Department of Anatomy and Histology, School of Medicine, Flinders University of South Australia, GPO Box 2100, Adelaide 5001, Australia. Y1 - 2004/01/09/ PY - 2004 DA - 2004 Jan 09 SP - 87 EP - 90 VL - 354 IS - 2 SN - 0304-3940, 0304-3940 KW - Uric Acid KW - 268B43MJ25 KW - Substance P KW - 33507-63-0 KW - Index Medicus KW - Sensory Receptor Cells -- pathology KW - Animals KW - Gout -- physiopathology KW - Nociceptors -- physiopathology KW - Nociceptors -- pathology KW - Gout -- pathology KW - Disease Models, Animal KW - Gout -- chemically induced KW - Arthralgia -- chemically induced KW - Sensory Receptor Cells -- metabolism KW - Chickens KW - Down-Regulation -- physiology KW - Sensory Receptor Cells -- physiopathology KW - Nociceptors -- metabolism KW - Arthralgia -- physiopathology KW - Arthralgia -- pathology KW - Immunohistochemistry KW - Male KW - Female KW - Tarsal Joints -- innervation KW - Arthritis -- pathology KW - Nerve Fibers -- pathology KW - Synovial Membrane -- physiopathology KW - Synovial Membrane -- innervation KW - Nerve Fibers -- metabolism KW - Substance P -- metabolism KW - Arthritis -- chemically induced KW - Arthritis -- physiopathology KW - Tarsal Joints -- physiopathology KW - Tarsal Joints -- pathology KW - Synovial Membrane -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/80076006?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neuroscience+letters&rft.atitle=Substance+P+immunoreactive+nerve+fibres+in+the+domestic+chick+ankle+joint+before+and+after+acute+urate+arthritis.&rft.au=Lunam%2C+C+A%3BGentle%2C+M+J&rft.aulast=Lunam&rft.aufirst=C&rft.date=2004-01-09&rft.volume=354&rft.issue=2&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Neuroscience+letters&rft.issn=03043940&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-03-11 N1 - Date created - 2003-12-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Clean Air Act Issues in the 108th Congress AN - 14690027; 10659757 AB - The energy bill, H.R. 6, submitted to Congress in November 2003, contains several Clean Air Act provisions. The most prominent of these concern MTBE and ethanol, which are used to meet requirements that reformulated gasoline sold in the worst ozone nonattainment areas contain at least 2% oxygen to improve combustion. The bill would ban the use of MTBE as a fuel additive nationwide, except in states that specifically authorize its use, after December 2014. By 2012, annual production of gasoline would be required to contain at least 5 billion gal of ethanol or other renewable fuel. Controversy over EPA's proposed and promulgated changes to the New Source Review requirements is also discussed. JF - US Congressional Research Service Report IB10107 AU - McCarthy, James E Y1 - 2004/01/09/ PY - 2004 DA - 2004 Jan 09 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - GASOLINE KW - EMISSION CONTROL STANDARDS KW - ETHANOL KW - CARBON DIOXIDE KW - AIR QUALITY STANDARDS KW - SULFUR DIOXIDE KW - LEGISLATION, FEDERAL KW - EPA, FEDERAL KW - CLEAN AIR ACT AMENDMENTS 90 KW - FUEL ADDITIVES KW - POWER PLANT EMISSION CONTROL KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14690027?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10107&rft.atitle=Clean+Air+Act+Issues+in+the+108th+Congress&rft.au=McCarthy%2C+James+E&rft.aulast=McCarthy&rft.aufirst=James&rft.date=2004-01-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10107&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-07180.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; ETHANOL; LEGISLATION, FEDERAL; GASOLINE; CARBON DIOXIDE; EMISSION CONTROL STANDARDS; AIR QUALITY STANDARDS; EPA, FEDERAL; CLEAN AIR ACT AMENDMENTS 90; POWER PLANT EMISSION CONTROL; MERCURY; FUEL ADDITIVES ER - TY - JOUR T1 - Phonemic characteristics of apraxia of speech resulting from subcortical hemorrhage. AN - 85373438; pmid-15013380 AB - Reports describing subcortical apraxia of speech (AOS) have received little consideration in the development of recent speech processing models because the speech characteristics of patients with this diagnosis have not been described precisely. We describe a case of AOS with aphasia secondary to basal ganglia hemorrhage. Speech-language symptoms consistent with subcortical AOS and aphasia are reported as well as description of the patient's speech characteristics using broad phonemic transcription. Significantly more phoneme substitution errors were observed than other types of errors and these occurred significantly more often in the initial rather than the medial or final positions of words. No differences were observed in the number of errors produced for the various types of phonemes included in this analysis. These findings challenge the hypothesis that speech motor planning disorders are uniquely the result of cortical damage. They also argue against the notion that subcortical AOS is indistinguishable from the cortical syndrome. LEARNING OUTCOMES: The reader will learn (1) the phonemic characteristics of AOS due to subcortical brain damage, (2) the similarities and differences between AOS due to cortical versus subcortical lesions, and (3) the implications of these patterns for current models of speech motor processing. JF - Journal of communication disorders AU - Peach, Richard K AU - Tonkovich, John D AD - Department of Otolaryngology, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA. richard_k_peach@rush.edu Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 77 EP - 90 VL - 37 IS - 1 SN - 0021-9924, 0021-9924 KW - Index Medicus KW - National Library of Medicine KW - Aged KW - *Apraxias: diagnosis KW - *Apraxias: etiology KW - *Cerebral Hemorrhage: complications KW - Humans KW - Male KW - *Phonetics KW - Severity of Illness Index UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85373438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+communication+disorders&rft.atitle=Phonemic+characteristics+of+apraxia+of+speech+resulting+from+subcortical+hemorrhage.&rft.au=Peach%2C+Richard+K%3BTonkovich%2C+John+D&rft.aulast=Peach&rft.aufirst=Richard&rft.date=2004-01-01&rft.volume=37&rft.issue=1&rft.spage=77&rft.isbn=&rft.btitle=&rft.title=Journal+of+communication+disorders&rft.issn=00219924&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - GEN T1 - Oral Somesthesis and Taste AN - 85311269; cs-292845 AB - The long-term goal of this project is to understand how the somesthetic and gustatory systems function together to produce oral sensations and flavors This goal will be pursued by taking advantage of three recent psychophysical findings that provide novel insights into how somatosensory stimulation can influence taste. First, studies will be conducted to investigate the phenomenon of thermal taste, in which tastes can be induced by temperature alone. Of particular interest are sources of individual and spatial variation in thermal taste, interactions between thermal taste and chemical taste, and the spatial and temporal characteristics of thermal tastes as they relate to the sensitivity to warmth and cold. Second, the induction and perception of 'phantom' tastes caused by brief bouts of cold stimulation on the front of the tongue will be investigated. These cold-induced phantoms (CIPs) are perceived after rather than during cold stimulation, and are localized away from rather than at the site of cooling. Experiments are proposed to test the hypothesis that CIPs, which reversibly mimic clinical dysgeusias, arise when putative tonic inhibition within and between oral sensory systems is interrupted by cold-block. Third, preliminary observations indicate that capsaicin, the prototypical 'trigeminal' irritant, can evoke significant bitterness in the circumvallate region of the tongue, and that both sensory irritation and perception of warmth are much weaker there than on the tongue tip. Experiments will investigate the possibility that some glossopharyngeal neurons that contribute to perception of bitterness are sensitive to irritants, and more generally, that the relationship between somesthesis and taste is different on the back of the tongue, where both kinds of stimulation are mediated solely by the glossopharyngeal nerve. Overall, these studies will advance our understanding of oral sensory processing in humans as well as provide data on sensory interactions that may be helpful in understanding the source of certain types of oral sensory pathologies (e.g., dysgeusias). JF - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519, nih; NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS, 2004 AU - GREEN, Barry G PY - 2004 PB - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85311269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Oral+Somesthesis+and+Taste&rft.au=GREEN%2C+Barry+G&rft.aulast=GREEN&rft.aufirst=Barry&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - GEN T1 - COMMONALITIES IN TOUCH, HEARING,VISION AND TASTE AN - 85310198; cs-293208 AB - DESCRIPTION: (Adapted from the Investigator's Abstract) With the broad goal of understanding principles common to processing sensory information in various modalities, this research aims to understand the role of voluntary attention in perception, particularly in the detection of weak sensory stimuli. In detecting auditory stimuli, people can attend selectively to information processed in different subpopulations of peripheral neural inputs (auditory listening-bands or attention-bands). A similar principle may operate in other modalities, such as touch and taste. Thus, selective attention may tap people's ability to monitor selectively a single channel (class of fibers) for the presence of neural information, e.g., Pacinian-based versus rapidly-adapting fibers in touch. (1) Experiments will use criterion-controlled psychophysical methods to test the hypothesis that channels analogous to auditory listening-bands also underlie the detection of weak tactile and gustatory stimuli. It is possible, however, that people can also attend selectively to stimuli that produce different patterns of neural activity within a single channel. Experiments will test this hypothesis directly. (2) In touch, spatial attention-the ability to attend to different parts of the body surface-appears to depend on inputs from proprioception (orientation of the head and eyes) and possibly vision; and in hearing, spatial attention may depend on visual inputs. Experiments will test the hypotheses that tactile spatial attention is linked to proprioception and that auditory spatial attention is linked to vision. (3) People can attend selectively to sounds having particular durations. The ability to attend selectively to sensory events having a particular duration could be a general property of perceptual systems. Experiments will test the hypothesis that temporal attention is a property of touch as well as hearing. (4) There is evidence for the existence in the Pacinian tactile system of energy thresholds, levels below which stimulation is indistinguishable from the absence of stimulation. Experiments will test two hypotheses: first, that energy thresholds are established subsequent to temporal and spatial summation in the Pacinian system, and second, that attention can operate by modulating these central energy thresholds. Taken together, these studies will elucidate basic mechanisms governing the role of attention in perception, and by doing so may ultimately help to advance our understanding of such disturbances of attention as those associated with communicative disorders, with brain injury and stroke, and with childhood learning disorders. JF - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519, nih; NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS, 2004 AU - MARKS, Lawrence E PY - 2004 PB - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85310198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=COMMONALITIES+IN+TOUCH%2C+HEARING%2CVISION+AND+TASTE&rft.au=MARKS%2C+Lawrence+E&rft.aulast=MARKS&rft.aufirst=Lawrence&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - GEN T1 - Neural substrates of taste, smell and flavor in humans AN - 85308391; cs-293646 AB - DESCRIPTION (provided by applicant): Our overarching goal is to define the neural substrates of taste and flavor in humans. This application is for a project that will use functional magnetic resonance imaging (fMRI) to measure brain response in healthy human volunteer subjects to tastes presented in isolation and tastes presented with odors. The neural substrates of taste must code for three major perceptual dimensions of taste; namely, intensity, affect, and quality. Previous studies comparing pleasant to unpleasant taste have not equated stimuli for intensity and no study has measured brain response to the different concentrations of the same taste. Our first specific aim is to determine brain regions coding for taste intensity versus taste pleasantness/unpleasantness. We will present subjects with two concentrations each of a pleasant and unpleasant taste while their brain response is measured with fMRI. Analyses will then be performed to isolate the brain response to intensity regardless of affective valence and affect regardless of intensity. Our second aim is to use fMRI to investigate brain correlates of simultaneous presentation of taste and smell versus independent presentation with either a taste or a smell. Congruent (vanilla odor with sweet taste) and incongruent (vanilla odor with salty taste) taste/smell pairs will be presented to investigate the effect of experience on integration. Additionally, mode of odor presentation (orthonasal versus retronasal delivery) will also be investigated. When taste and smell co-occur naturally the odor is perceived via the retronasal route. We thus predict differential integration of odor with taste favoring the retronasal route. Understanding the neural correlates of taste and flavor offers a mechanism by which limbic system function can be probed in health and disease. For example, the response function of the fMRI signal to taste concentration may be used as an objective probe for limbic system response in an analogous way that the flickering checkerboard has been used to define the characteristics of the fMRI signal in the visual cortex. Furthermore, imaging studies of taste intensity response may also be used to demonstrate the integrity of limbic system function in patient populations with suspected limbic system involvement (e.g., Alzheimer's disease) or patients who may respond abnormally to food stimuli (e.g., bulimia). This research will also provide important information into the nature of polymodal sensory integration. JF - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519, nih; NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS, 2004 AU - SMALL, Dana M PY - 2004 PB - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85308391?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Neural+substrates+of+taste%2C+smell+and+flavor+in+humans&rft.au=SMALL%2C+Dana+M&rft.aulast=SMALL&rft.aufirst=Dana&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - GEN T1 - Mechanisms of Taste- & Taste-Olfaction Mixture Detection AN - 85289486; cs-281362 AB - DESCRIPTION (provided by applicant): Most foods and beverages have 'tastes' (or, more appropriately, 'flavors'), and these result from the integration of neural inputs deriving from several sense modalities: gustation, or taste proper; olfaction; and even somatosensation (touch, temperature, sometimes pungency or irritation). Further, most stimuli that produce perceptions of taste and flavor consist of mixtures of large numbers of individual chemical constituents, and the perception of mixtures depends ultimately on central neural mechanisms that integrate signals arising within and among modalities. The present research focuses on mechanisms underlying the detection, by humans, of taste mixtures (mixtures of gustatory stimuli) and taste-olfactory mixtures (mixtures of gustatory and olfactory stimuli) when stimuli are flowed over the tongue or taken into the mouth. It is likely that at least four neural channels can operate independently in the threshold-level detection of gustatory and olfactory taste/flavor stimuli. Given this, and given that detection reflects discrimination of signal from noise (signal detection theory), a series of experiments will test the predictions of a quantitative model of central integration of statistically independent channels. This model, the integration model, predicts partial summation of signals arising from stimuli that activate independent channels. Tested also are two alternative quantitative models. One of these, a model of complete independence, predicts probability summation, which implies less summation than that predicted by the integration model; the other alternative, stimulus summation, is a model that assumes that stimuli have additive effects within a single channel, and this model typically predicts greater summation than does the integration model. The first set of experiments measures sensitivity to mixtures of gustatory and olfactory stimuli taken in the mouth. The second set of experiments measures sensitivity to mixtures of gustatory stimuli. The third set of experiments asks whether subjects are able to use probability summation to improve the detection of taste-olfaction mixtures. And the fourth set of experiments tests the hypothesis that channel-independence will fail in a paradigm of cross-channel cross modal, gustatory-olfactory) masking, when background maskers are well above threshold. JF - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519, nih; NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS, 2004 AU - MARKS, Lawrence E PY - 2004 PB - JOHN B. PIERCE LABORATORY, INC.; 290 CONGRESS AVE; NEW HAVEN, CT 06519 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85289486?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Mechanisms+of+Taste-+%26amp%3B+Taste-Olfaction+Mixture+Detection&rft.au=MARKS%2C+Lawrence+E&rft.aulast=MARKS&rft.aufirst=Lawrence&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Acupuncture for induction of labour. AN - 80174598; 14973999 AB - This is one of a series of reviews of methods of cervical ripening and labour induction using standardised methodology. The use of complementary therapies is increasing and some women look to complementary therapies during pregnancy and childbirth to be used alongside conventional medical practice. Acupuncture involves the insertion of very fine needles into specific points of the body. The limited observational studies to date suggest acupuncture for induction of labour appears safe, has no known teratogenic effects, and may be effective. The evidence regarding the clinical effectiveness of this technique is limited. To determine the effects of acupuncture for third trimester cervical ripening or induction of labour. The Cochrane Pregnancy and Childbirth Group trials register (February 2003), the Cochrane Central Register of Controlled Trials (The Cochrane Library, Issue 1, 2003), PubMed (1966 to present), CISCOM (1960 to present), EMBASE (1980 to present) and bibliographies of relevant papers. Clinical trials comparing acupuncture used for third trimester cervical ripening or labour induction with placebo/no treatment or other methods listed above it on a predefined list of labour induction methods. A strategy was developed to deal with the large volume and complexity of trial data relating to labour induction. This involved a two-stage method of data extraction. One trial of 56 women was included in the review. Data were not in a form that could be included in the meta-analysis. There is a need for well-designed randomised controlled trials to evaluate the role of acupuncture to induce labour and for trials to assess clinically meaningful outcomes. JF - The Cochrane database of systematic reviews AU - Smith, C A AU - Crowther, C A AD - School of Health Sciences, University of South Australia, City East Campus, GPO Box 2471, Adelaide, South Australia, Australia. Y1 - 2004 PY - 2004 DA - 2004 SP - 1 IS - 1 KW - Index Medicus KW - Randomized Controlled Trials as Topic KW - Humans KW - Cervical Ripening KW - Female KW - Pregnancy KW - Acupuncture Therapy KW - Labor, Induced -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/80174598?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Cochrane+database+of+systematic+reviews&rft.atitle=Acupuncture+for+induction+of+labour.&rft.au=Smith%2C+C+A%3BCrowther%2C+C+A&rft.aulast=Smith&rft.aufirst=C&rft.date=2004-01-01&rft.volume=&rft.issue=1&rft.spage=CD002962&rft.isbn=&rft.btitle=&rft.title=The+Cochrane+database+of+systematic+reviews&rft.issn=1469-493X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-29 N1 - Date created - 2004-02-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Update In: Cochrane Database Syst Rev. 2013;8:CD002962 [23945980] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Benzene and lead exposure assessment among occupational bus drivers in Bangkok traffic. AN - 80169735; 14971454 AB - Four environmental and biological monitoring sites were strategically established to evaluate benzene and lead exposure assessment at various traffic zones of Bangkok Metropolitan Region(BMR). Biological measurement of 48 non air-conditioned, male bus drivers was carried to study the relationship between individual exposure levels and exposure biomarkers. The study group was further subdivided into four age groups(16-25, 26-35, 36-45 and 46-55 years old) to monitor the age-related exposure effects. A total of 12 unexposed persons were deliberately chosen as the control group. Measurement of unmetobolized benzene in blood and analysis of urinary tt-Muconic acid urine and urinary creatinine are recommended as biomarkers of benzene exposure. Measurement of lead in blood and urine is also recommended for the biological monitoring of lead exposure. During the monitoring period, benzene and lead levels at Yaowarat Road was C6H6: 42.46 +/- 3.88 microg/m3 , Pb: 0.29 +/- 0.03 microg/m3 and decreased to C6H6: 33.5 +/- 1.35 microg/m3, Pb: 0.13 +/- 0.01 microg/m3 at Phahonyothin Road. Significant difference was established between the nonsmoking exposed group and nonsmoking control group for blood benzene concentrations (P < 0.001, two-tailed, Mann-Whiteney U test). Strong correlations were also found between trans-trans-Muconic acid concentrations in post shift samples and atmospheric benzene concentrations. Similarly, good correlation between all of biomarkers and lead level in air is established from automobile emissions. The analysis revealed that among the occupational population in the urban sites, the driver groups were found to have the highest risk of benzene and lead exposures derived from automobile emission. JF - Journal of environmental sciences (China) AU - Muttamara, S AU - Leong, Shing Tet AU - Arayasiri, M AD - Research Lab Supervisor, Urban Environmental Engineering and Management Program, School of Environment, Resource and Development, Asian Institute of Technology, G.P.O. Box 4, Klong Luang, Pathumthani 12120, Thailand. tet@ait.ac.th Y1 - 2004 PY - 2004 DA - 2004 SP - 61 EP - 66 VL - 16 IS - 1 SN - 1001-0742, 1001-0742 KW - Vehicle Emissions KW - 0 KW - Lead KW - 2P299V784P KW - Benzene KW - J64922108F KW - Index Medicus KW - Environmental Monitoring KW - Transportation KW - Thailand KW - Humans KW - Adult KW - Middle Aged KW - Adolescent KW - Urban Population KW - Male KW - Occupational Exposure KW - Lead -- urine KW - Benzene -- analysis KW - Lead -- analysis KW - Lead -- blood KW - Vehicle Emissions -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/80169735?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+sciences+%28China%29&rft.atitle=Benzene+and+lead+exposure+assessment+among+occupational+bus+drivers+in+Bangkok+traffic.&rft.au=Muttamara%2C+S%3BLeong%2C+Shing+Tet%3BArayasiri%2C+M&rft.aulast=Muttamara&rft.aufirst=S&rft.date=2004-01-01&rft.volume=16&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+sciences+%28China%29&rft.issn=10010742&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-14 N1 - Date created - 2004-02-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: J Environ Sci (China). 2004;16(2):186 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A case of herceptin cardiotoxicity. AN - 80076511; 14704598 JF - American journal of therapeutics AU - Cobleigh, Melody AU - Somberg, John C AD - Comprehensive Breast Center, Rush University, Rush-Presbyterian St. Luke's Medical Center, 1653 W. Congress Parkway, 1589 Jelke, Chicago, IL 60612-3833, USA. PY - 2004 SP - 74 EP - 76 VL - 11 IS - 1 SN - 1075-2765, 1075-2765 KW - Antibodies, Monoclonal KW - 0 KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Agents KW - Trastuzumab KW - P188ANX8CK KW - Index Medicus KW - Breast Neoplasms -- drug therapy KW - Aged, 80 and over KW - Humans KW - Aged KW - Female KW - Hypertension -- chemically induced KW - Angina Pectoris -- chemically induced KW - Antibodies, Monoclonal -- adverse effects KW - Antineoplastic Agents -- therapeutic use KW - Antineoplastic Agents -- adverse effects KW - Antibodies, Monoclonal -- therapeutic use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/80076511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+therapeutics&rft.atitle=A+case+of+herceptin+cardiotoxicity.&rft.au=Cobleigh%2C+Melody%3BSomberg%2C+John+C&rft.aulast=Cobleigh&rft.aufirst=Melody&rft.date=2004-01-01&rft.volume=11&rft.issue=1&rft.spage=74&rft.isbn=&rft.btitle=&rft.title=American+journal+of+therapeutics&rft.issn=10752765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-04 N1 - Date created - 2004-01-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Brine shrimp toxicity and antiplasmodial activity of five Kenyan medicinal plants. AN - 80074123; 14698520 AB - The organic extracts of leaves and roots of five plants used for treating malaria in Central, Nairobi and Rift Valley Provinces, Kenya were tested for brine shrimp lethality and in vitro antiplasmodial activity against chloroquine sensitive and resistant strains of Plasmodium falciparum. Of the plants tested, 60% were toxic to the brine shrimp (LC(50)<30 microg/ml) and eight out of ten plant parts (80%) showed in vitro antiplasmodial activity (IC(50)<50 microg/ml). Among the extracts screened, the leaves of Cyathula polcephala had the highest toxicity to the brine shrimp (LC(50)=2.9 microg/ml) while the leaves of Pentas longiflora had the best antiplasmodial activity (IC(50)=11. /ml). The plant extracts with low IC(50) values are potential sources for novel antiplasmodial compounds. JF - Journal of ethnopharmacology AU - Wanyoike, G N AU - Chhabra, S C AU - Lang'at-Thoruwa, C C AU - Omar, S A AD - Chemistry Department, School of Pure & Applied Sciences, Kenyatta University, 00100 GPO, PO Box 43844, Nairobi, Kenya. Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 129 EP - 133 VL - 90 IS - 1 SN - 0378-8741, 0378-8741 KW - Antimalarials KW - 0 KW - Plant Extracts KW - Index Medicus KW - Animals KW - Plant Roots KW - Kenya KW - Plant Leaves KW - Plants, Medicinal KW - In Vitro Techniques KW - Drug Resistance KW - Inhibitory Concentration 50 KW - Medicine, African Traditional KW - Plasmodium falciparum -- drug effects KW - Artemia -- drug effects KW - Antimalarials -- toxicity KW - Plant Extracts -- pharmacology KW - Antimalarials -- pharmacology KW - Plant Extracts -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/80074123?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+ethnopharmacology&rft.atitle=Brine+shrimp+toxicity+and+antiplasmodial+activity+of+five+Kenyan+medicinal+plants.&rft.au=Wanyoike%2C+G+N%3BChhabra%2C+S+C%3BLang%27at-Thoruwa%2C+C+C%3BOmar%2C+S+A&rft.aulast=Wanyoike&rft.aufirst=G&rft.date=2004-01-01&rft.volume=90&rft.issue=1&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=Journal+of+ethnopharmacology&rft.issn=03788741&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-07-02 N1 - Date created - 2003-12-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Quality evaluation of honey harvested from selected areas in Tanzania with special emphasis on hydroxymethyl furfural (HMF) levels. AN - 67229652; 15678719 AB - The physicochemical properties of honey harvested from popular honey-producing areas in Tanzania were investigated. Honey from Shibe-Dodoma had the highest values of specific gravity, total acidity, free fatty acid content, diastatic number, overall acceptability, and lowest hydroxymethyl-furfural (HMF) level as compared to honey samples from other areas. There was no significant difference (p > 0.05) in terms of HMF in the other honey samples from Tanga, Morogoro, Same, Arusha, and Tabora. HMF levels in all honey samples were far below the maximum acceptable level of 40 mg/kg as recommended by the Codex Alimentarius Commission Standards before storage for 6 months. No traces of streptomycin and phenol were detected in all honey samples. It was concluded that according to the values of the studied quality parameters, the types of Tanzanian honey obtained from the popular honey producing areas may be judged to be of high quality. JF - Plant foods for human nutrition (Dordrecht, Netherlands) AU - Gidamis, Andrew B AU - Chove, Bernard E AU - Shayo, Nicholas B AU - Nnko, Siphuel A AU - Bangu, Nicholas T AD - African Institute fir Capacity Development (AICAD). P.O. Box 46179, GPO 00100. Nairobi. Kenya. Y1 - 2004 PY - 2004 DA - 2004 SP - 129 EP - 132 VL - 59 IS - 3 SN - 0921-9668, 0921-9668 KW - Fatty Acids, Volatile KW - 0 KW - Phenols KW - 5-hydroxymethylfurfural KW - 70ETD81LF0 KW - Furaldehyde KW - DJ1HGI319P KW - Index Medicus KW - Tanzania KW - Nutritive Value KW - Hydrogen-Ion Concentration KW - Food Handling -- methods KW - Food Contamination -- analysis KW - Fatty Acids, Volatile -- analysis KW - Geography KW - Time Factors KW - Quality Control KW - Phenols -- analysis KW - Honey -- analysis KW - Furaldehyde -- analysis KW - Honey -- standards KW - Furaldehyde -- analogs & derivatives UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67229652?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+foods+for+human+nutrition+%28Dordrecht%2C+Netherlands%29&rft.atitle=Quality+evaluation+of+honey+harvested+from+selected+areas+in+Tanzania+with+special+emphasis+on+hydroxymethyl+furfural+%28HMF%29+levels.&rft.au=Gidamis%2C+Andrew+B%3BChove%2C+Bernard+E%3BShayo%2C+Nicholas+B%3BNnko%2C+Siphuel+A%3BBangu%2C+Nicholas+T&rft.aulast=Gidamis&rft.aufirst=Andrew&rft.date=2004-01-01&rft.volume=59&rft.issue=3&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=Plant+foods+for+human+nutrition+%28Dordrecht%2C+Netherlands%29&rft.issn=09219668&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-03-03 N1 - Date created - 2005-01-31 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Peptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotides. AN - 67180012; 15602001 AB - Triplex-forming oligonucleotides (TFOs) are DNA-binding molecules, which offer the potential to selectively modulate gene expression. However, the biological activity of TFOs as potential antigene compounds has been limited by cellular uptake. Here, we investigate the effect of cell-penetrating peptides on the biological activity of TFOs as measured in an assay for gene-targeted mutagenesis. Using the transport peptide derived from the third helix of the homeodomain of antennapedia (Antp), we tested TFO-peptide conjugates compared with unmodified TFOs. TFOs covalently linked to Antp resulted in a 20-fold increase in mutation frequency when compared with 'naked' oligonucleotides. There was no increase above background in mutation frequency when Antp by itself was added to the cells or when Antp was linked to mixed or scrambled sequence control oligonucleotides. In addition, the TFO-peptide conjugates increased the mutation frequency of the target gene, and not the control gene, in a dose-responsive manner. Confocal microscopy using labeled oligonucleotides indicated increased cellular uptake of TFOs when linked to Antp, consistent with the gene-targeting data. These results suggest that peptide conjugation may enhance intranuclear delivery of reagents designed to bind to chromosomal DNA. JF - Nucleic acids research AU - Rogers, Faye A AU - Manoharan, Muthiah AU - Rabinovitch, Peter AU - Ward, David C AU - Glazer, Peter M AD - Department of Therapeutic Radiology, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 068520, USA. Y1 - 2004 PY - 2004 DA - 2004 SP - 6595 EP - 6604 VL - 32 IS - 22 KW - Antennapedia Homeodomain Protein KW - 0 KW - Homeodomain Proteins KW - Nuclear Proteins KW - Oligonucleotides KW - Transcription Factors KW - triplex DNA KW - DNA KW - 9007-49-2 KW - Index Medicus KW - Microscopy, Confocal KW - Animals KW - Biological Transport KW - DNA -- chemistry KW - Mice KW - Mutation KW - Cell Line KW - Mutagenesis KW - Oligonucleotides -- pharmacology KW - Oligonucleotides -- chemistry KW - Transcription Factors -- chemistry KW - Nuclear Proteins -- chemistry KW - Chromosomes -- drug effects KW - Oligonucleotides -- metabolism KW - Gene Targeting KW - Homeodomain Proteins -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67180012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nucleic+acids+research&rft.atitle=Peptide+conjugates+for+chromosomal+gene+targeting+by+triplex-forming+oligonucleotides.&rft.au=Rogers%2C+Faye+A%3BManoharan%2C+Muthiah%3BRabinovitch%2C+Peter%3BWard%2C+David+C%3BGlazer%2C+Peter+M&rft.aulast=Rogers&rft.aufirst=Faye&rft.date=2004-01-01&rft.volume=32&rft.issue=22&rft.spage=6595&rft.isbn=&rft.btitle=&rft.title=Nucleic+acids+research&rft.issn=1362-4962&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-01-21 N1 - Date created - 2004-12-16 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Trends Pharmacol Sci. 2000 Mar;21(3):99-103 [10689363] J Biol Chem. 1999 Sep 10;274(37):26369-77 [10473594] Biochem Pharmacol. 2000 Jul 1;60(1):83-90 [10807948] Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9003-8 [10900269] Bioconjug Chem. 2000 Sep-Oct;11(5):605-18 [10995203] Science. 2000 Oct 20;290(5491):530-3 [11039937] Curr Opin Mol Ther. 2000 Jun;2(3):288-96 [11249623] J Biol Chem. 2001 May 25;276(21):18018-23 [11278954] Hum Mol Genet. 2001 Oct 1;10(20):2243-51 [11673407] Antisense Nucleic Acid Drug Dev. 2002 Feb;12(1):43-9 [12022689] J Biol Chem. 2003 Jan 3;278(1):585-90 [12411431] Nucleic Acids Res. 2003 Jan 15;31(2):556-61 [12527762] Bioconjug Chem. 2003 May-Jun;14(3):532-8 [12757376] Biochem Biophys Res Commun. 2003 Jul 18;307(1):100-7 [12849987] J Mol Recognit. 2003 Sep-Oct;16(5):272-9 [14523940] Proc Natl Acad Sci U S A. 1986 Feb;83(4):1041-4 [2937054] Proc Natl Acad Sci U S A. 1989 Sep;86(17):6454-8 [2549537] Proc Natl Acad Sci U S A. 1991 Jul 1;88(13):5602-6 [2062839] Nucleic Acids Res. 1992 Jan 25;20(2):307-14 [1741256] Science. 1993 Aug 20;261(5124):1004-12 [8351515] Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7879-83 [8356097] Nucleic Acids Res. 1993 Aug 11;21(16):3903-4 [8396240] Antisense Res Dev. 1993 Fall;3(3):265-75 [8286927] J Biol Chem. 1994 Jan 28;269(4):2550-61 [8300583] J Biol Chem. 1994 Apr 8;269(14):10444-50 [8144628] Bioconjug Chem. 1994 Jul-Aug;5(4):373-8 [7948105] Nucleic Acids Res. 1994 Nov 11;22(22):4681-8 [7984418] J Cell Biol. 1995 Mar;128(5):919-27 [7876315] Cancer Res. 1995 Mar 15;55(6):1283-8 [7882323] Nucleic Acids Res. 1995 Jun 11;23(11):1956-63 [7596824] Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3176-81 [8622909] Science. 1996 Feb 9;271(5250):802-5 [8628995] DNA Cell Biol. 1996 Mar;15(3):209-25 [8634150] Biochemistry. 1996 Aug 20;35(33):10712-9 [8718860] Trends Genet. 1996 Oct;12(10):400-5 [8909136] Curr Opin Neurobiol. 1996 Oct;6(5):629-34 [8937827] Nucleic Acids Res. 1997 Feb 1;25(3):633-40 [9016606] Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3122-7 [9096356] J Biol Chem. 1997 Jun 20;272(25):16010-7 [9188504] Gene. 1997 Sep 15;197(1-2):253-60 [9332373] Mol Membr Biol. 1998 Jan-Mar;15(1):1-14 [9595549] Antisense Nucleic Acid Drug Dev. 1998 Jun;8(3):215-25 [9669659] Trends Cell Biol. 1998 Feb;8(2):84-7 [9695814] Nucleic Acids Res. 1999 Feb 15;27(4):1176-81 [9927753] J Biol Chem. 1999 Apr 23;274(17):11541-8 [10206960] Bioconjug Chem. 1999 Jul-Aug;10(4):598-606 [10411457] Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):3862-7 [10760257] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Recent advances in neuroproteomics and potential application to studies of drug addiction. AN - 66946277; 15464134 AB - The rapidly growing field of proteomics seeks to track changes in protein expression function that underlie the growth and differentiation of individual cell types, both during normal development and during the onset and progression of disease. Recent years have seen great strides in mRNA expression analysis, and the development of new technologies for protein profiling. However, current methods are limited to analysis of the relative expression level of only a few hundred to perhaps 2000 proteins, well below the ability of DNA microarrays to potentially interrogate the mRNA expression of more than 25,000 genes. Proteomics faces a special challenge in studies of the nervous system, where cellular and sub-cellular architecture is among the most complex in the body. This article presents an overview of current proteomic profiling technologies, reviews the recent use of some of these approaches in studies of the nervous system, and discusses the potential application of neuroproteomics to studies of drug addiction. JF - Neuropharmacology AU - Williams, Kenneth AU - Wu, Terence AU - Colangelo, Christopher AU - Nairn, Angus C AD - Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536-0812, USA. Y1 - 2004 PY - 2004 DA - 2004 SP - 148 EP - 166 VL - 47 Suppl 1 SN - 0028-3908, 0028-3908 KW - Neuropeptides KW - 0 KW - Phosphoproteins KW - Index Medicus KW - Animals KW - Mass Spectrometry KW - Neuropeptides -- physiology KW - Brain Chemistry -- drug effects KW - Humans KW - Protein Processing, Post-Translational KW - Neuropeptides -- biosynthesis KW - Protein Array Analysis KW - Brain Chemistry -- genetics KW - Electrophoresis, Gel, Two-Dimensional KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Neuropeptides -- chemistry KW - Neuropeptides -- genetics KW - Phosphoproteins -- metabolism KW - Proteomics -- trends KW - Neurosciences -- trends KW - Substance-Related Disorders -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66946277?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neuropharmacology&rft.atitle=Recent+advances+in+neuroproteomics+and+potential+application+to+studies+of+drug+addiction.&rft.au=Williams%2C+Kenneth%3BWu%2C+Terence%3BColangelo%2C+Christopher%3BNairn%2C+Angus+C&rft.aulast=Williams&rft.aufirst=Kenneth&rft.date=2004-01-01&rft.volume=47+Suppl+1&rft.issue=&rft.spage=148&rft.isbn=&rft.btitle=&rft.title=Neuropharmacology&rft.issn=00283908&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-12-20 N1 - Date created - 2004-10-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Toxicity and residues of endosulfan isomers. AN - 66874923; 15369323 AB - The continued availability of endosulfan is desirable for the production of cotton, and various other crops, because of its particular suitability for use in IPM and resistance management strategies. However, ongoing residue problems threaten the availability of the insecticide. Data described here suggest a beta-enriched insecticide is worthy of investigation as a useful alternative organochloride insecticide, having the advantages of reduced environmental and health concerns. The alpha-isomer of endosulfan is an order of magnitude more volatile than the beta-isomer, which is reflected in its initial rapid disappearance in the field. Approximately 70% of endosulfan is lost within 2 d of application due to volatilization. Based on volatilization kinetics, the volatilization of a beta-endosulfan formulation would be less than 5% that of commercial endosulfan. However, while it has been established that endosulfan vapor does lead to contamination of the riverine environment, this contamination is below residue levels recorded in rivers during the cotton growing season and, as such, reducing the volatility of the insecticide will only partially alleviate residue problems. Initial field trial results suggest that beta-endosulfan insecticide can achieve equivalent efficacy to commercial endosulfan at half the recommended label application rate; presumably this is a reflection of its containment on site in comparison to the more volatile commercial mix of isomers. An insecticide composed primarily of the beta-isomer would have reduced volatility and equivalent efficacy at lower application rates compared to the commercial mix of isomers, reducing offsite endosulfan residues. An important advantage of a beta-enriched insecticide would be its potential to minimize endosulfan residues in locally grown production animals. The predominant endosulfan residue in animal fat is endosulfate, accumulated after the animal ingests the metabolite while grazing on pastures contaminated by endosulfan spray drift. As the beta-isomer is oxidized on the surface of plants and by microbes at much lower rates than the alpha-isomer, endosulfate levels would be lower as a result of a contamination event with a beta-endosulfan-based insecticide compared to the commercial mix. Finally, acute toxicity against mammals of the alpha-isomer is more than three times that of the beta-isomer, and the neurotoxicity of the insecticide has been attributed to the alpha-isomer. Therefore, a beta-enriched insecticide will be less acutely and chronically toxic to agricultural workers than the commercially available insecticide. In conclusion, these properties suggest that the alpha-isomer contributes more significantly to the residue problems associated with the insecticide than the beta-isomer and that the use of a beta-isomer-based insecticide would reduce residue problems yet retain the advantages to IPM and resistant management strategies unique to the current endosulfan formulation. JF - Reviews of environmental contamination and toxicology AU - Sutherland, Tara D AU - Home, Irene AU - Weir, Kahli M AU - Russell, Robyn J AU - Oakeshott, John G AD - CSIRO Entomology, GPO Box 1700, Canberra ACT 2601, Australia. Y1 - 2004 PY - 2004 DA - 2004 SP - 99 EP - 113 VL - 183 SN - 0179-5953, 0179-5953 KW - Hydrocarbons, Chlorinated KW - 0 KW - Insecticides KW - Endosulfan KW - OKA6A6ZD4K KW - Index Medicus KW - Animals KW - Half-Life KW - Isomerism KW - Insecticides -- toxicity KW - Endosulfan -- chemistry KW - Insecticides -- chemistry KW - Endosulfan -- toxicity KW - Environmental Pollution KW - Insects -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66874923?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reviews+of+environmental+contamination+and+toxicology&rft.atitle=Toxicity+and+residues+of+endosulfan+isomers.&rft.au=Sutherland%2C+Tara+D%3BHome%2C+Irene%3BWeir%2C+Kahli+M%3BRussell%2C+Robyn+J%3BOakeshott%2C+John+G&rft.aulast=Sutherland&rft.aufirst=Tara&rft.date=2004-01-01&rft.volume=183&rft.issue=&rft.spage=99&rft.isbn=&rft.btitle=&rft.title=Reviews+of+environmental+contamination+and+toxicology&rft.issn=01795953&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-10-21 N1 - Date created - 2004-09-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A radon and meteorological measurement network for the Alligator Rivers Region, Australia. AN - 66698198; 15245839 AB - The network described in this paper has been set up to provide detailed time-series data on concentrations of 222Rn in air at various locations within the Alligator Rivers Region, over a time frame of several years. These data will be important in assessing the effects of uranium mining operations on radon levels in the region, both in providing baseline and monitoring data and in calibrating and verifying predictive models. At present, three stations are operating in the region with a fourth being commissioned. Each station logs half hourly average radon concentrations and relevant meteorological data (wind speed, direction and variability, air pressure and temperature, relative humidity, soil temperature, rain and sunshine rates). It is intended to operate the four stations at selected locations for one- or two-year intervals, at the end of which three will be moved to new locations (one station at Mudginberri will be kept as a constant control station). Sites for which extensive datasets are currently available include: Jabiru Town, Jabiru East, Djarr Djarr, East Alligator Ranger Station and Nabarlek minesite. Illustrative data from these sites are presented. JF - Journal of environmental radioactivity AU - Martin, P AU - Tims, S AU - Ryan, B AU - Bollhöfer, A AD - Environmental Research Institute of the Supervising Scientist (eriss), GPO Box 461, Darwin 0801, Australia. paul.martin@deh.gov.au Y1 - 2004 PY - 2004 DA - 2004 SP - 35 EP - 49 VL - 76 IS - 1-2 SN - 0265-931X, 0265-931X KW - Air Pollutants, Radioactive KW - 0 KW - Radon KW - Q74S4N8N1G KW - Index Medicus KW - Environmental Monitoring KW - Reference Values KW - Meteorological Concepts KW - Australia KW - Radon -- analysis KW - Air Pollutants, Radioactive -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66698198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+radioactivity&rft.atitle=A+radon+and+meteorological+measurement+network+for+the+Alligator+Rivers+Region%2C+Australia.&rft.au=Martin%2C+P%3BTims%2C+S%3BRyan%2C+B%3BBollh%C3%B6fer%2C+A&rft.aulast=Martin&rft.aufirst=P&rft.date=2004-01-01&rft.volume=76&rft.issue=1-2&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+radioactivity&rft.issn=0265931X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-09 N1 - Date created - 2004-07-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Creating Tesselations with Pavement Chalk: Implementing Best Practices in Mathematics AN - 62076974; EJ743547 AB - Implementing best practices like cooperative learning, using concrete manipulatives, problem solving, technology, active learning, multi-age grouping, and team teaching have shown benefits for students when learning mathematics concepts within the curriculum (Zemelman, Daniels & Hyde, 1998; NCTM, 2000). What started as a professional development teacher improvement exercise by a Year 2 and Year 4 teacher has turned into a powerful learning experience for the teachers, students, and the school. Teachers teaching together from different year levels and backgrounds of kids working together are finding great success. This article will explore a lesson on geometry and spatial sense and tessellations which turned into a memorable experience for all the students and teachers. Teachers are beginning to see what really works to get students thinking like mathematicians and enjoying the discipline. JF - Australian Mathematics Teacher AU - Furner, Joseph M. AU - Goodman, Barbara AU - Meeks, Shirley Y1 - 2004 PY - 2004 DA - 2004 SP - 25 EP - 28 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 2 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Mixed Age Grouping KW - Cooperative Learning KW - Mathematics Instruction KW - Geometric Concepts KW - Teacher Improvement KW - Learning Experience KW - Problem Solving KW - Student Experience KW - Teaching Experience KW - Mathematical Enrichment KW - Parent Participation KW - Geometry KW - Faculty Development KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62076974?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4343 6410 5964; 4339 6396; 10609 3685 853; 10208 3685 853; 10621 3227 6582; 10525 4999; 8233 1710; 2225 5882; 6419 5242; 5893 3685 853; 3787 8258 5704 2787 10010; 6733 1595 7404; 6397 3500; 7550 7615 909 ER - TY - JOUR T1 - A Cabri Geometry Teaching Sequence AN - 62075608; EJ743538 AB - In early 2004, Cabrilog released version "II plus" of their interactive geometry package. According to the author, "Cabri Geometry II plus" is clearly a much more useful package than the earlier version. However, unlike other sophisticated applications packages, the designers have avoided creating so many options that secondary students lose their way among the menu items. In this article, the author suggests a geometry teaching sequence for beginners using the "Cabri Geometry II plus" package. JF - Australian Mathematics Teacher AU - Hyde, Hartley Y1 - 2004 PY - 2004 DA - 2004 SP - 2 EP - 3 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 2 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Secondary Education KW - Sequential Learning KW - Mathematics Activities KW - Courseware KW - Secondary School Mathematics KW - Secondary School Students KW - Geometry KW - Computer Assisted Instruction KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62075608?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4343 6410 5964; 9540 5882; 2352 5258 3224 2059; 6412 126; 9419 10278 8016 4542; 9417 9414 2515 6416; 10621 3227 6582; 2015 2074 2073 10675 ER - TY - JOUR T1 - The Swiss Event at the University of Canberra Maths Day AN - 62071847; EJ743533 AB - An event based on "find the rule" problems has been part of the University of Canberra Maths Day since 1985. In this paper, the authors describe the Swiss event, its context, its aims, its logistics, and gives examples of problems used in past events. The type of problems used, how they are used in an event at the maths day, and how the event evens out the competition and stops strong schools dominating are also discussed. JF - Australian Mathematics Teacher AU - Clark, David AU - Brooks, Malcolm Y1 - 2004 PY - 2004 DA - 2004 SP - 6 EP - 11 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 1 SN - 0045-0685, 0045-0685 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Higher Education KW - Foreign Countries KW - Cultural Activities KW - Mathematics Activities KW - Mathematical Enrichment KW - Competition KW - Problem Solving KW - Mathematics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62071847?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 2464 126; 6410 5964; 6397 3500; 6412 126; 8233 1710; 4109 4335; 1974 909 ER - TY - JOUR T1 - What Is All This Lifelong Learning Stuff? AN - 62070452; EJ743553 AB - Education systems around the world are talking about "lifelong learning", "futures", "critical literacies", and so on. What do these things mean in the context of being a teacher of mathematics? In this article, the author attempts to put these things into perspective. She contends that, in clarifying any situation that requires some mathematical application, teachers need to be modelling and teaching students how to ask questions, how to identify issues, how to focus on what is required, how to verbalise their thinking processes as they do this and how to organise their thinking. JF - Australian Mathematics Teacher AU - Perso, Thelma Y1 - 2004 PY - 2004 DA - 2004 SP - 36 EP - 40 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 2 SN - 0045-0685, 0045-0685 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - High Schools KW - Secondary Education KW - Thinking Skills KW - Questioning Techniques KW - Lifelong Learning KW - Secondary School Students KW - Secondary School Teachers KW - Mathematics Education KW - Foreign Countries KW - Cognitive Processes KW - Educational Practices KW - Educational Change KW - Mathematics Teachers KW - College Preparation KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62070452?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6055 5882; 6422 10591 8267 3417 8016 4542 5703 4908 8917; 6417 3150; 3176 1387; 3242; 10621 3227 6582; 1791 9409 3368 3150; 9419 10278 8016 4542; 9420 10591 8267 3417 8016 4542 5703 4908 8917; 8534 6582; 1710; 10852 1701 1 9690; 4109 4335 ER - TY - JOUR T1 - Paul Erdos AN - 62070357; EJ743541 AB - This article presents a brief biography of Paul Erdos, who focused on problem-solving, particularly in the areas of number theory, combinatorics and graph theory. During his life he had no property, no family and no fixed address. He buttered his first piece of bread at age 21. He never cooked, nor ever drove a car. Another mathematician, Ron Graham, took care of his daily financial accounting. Erdos'approach to mathematics was as unique as his life. He invented a new kind of art: the art of raising problems. He said that mathematics is eternal because it has an infinity of problems; and in his view, the more elementary a problem is, the better. He loved areas of mathematics which did not require an excessive amount of technical knowledge but give scope for ingenuity and surprise. JF - Australian Mathematics Teacher AU - Monroe, Helen AU - Scott, Paul Y1 - 2004 PY - 2004 DA - 2004 SP - 14 EP - 16 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 2 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Theories KW - Mathematical Concepts KW - Philosophy KW - Numbers KW - Problem Solving KW - Mathematics KW - Biographies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62070357?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 990 6113 7104 8371 6120 4918 5964; 6410 5964; 8233 1710; 6396; 10830; 7195 10407; 7807 4918 5964 ER - TY - JOUR T1 - Euler and His Contribution Number Theory AN - 62069840; EJ743532 AB - Born in 1707, Leonhard Euler was the son of a Protestant minister from the vicinity of Basel, Switzerland. With the aim of pursuing a career in theology, Euler entered the University of Basel at the age of thirteen, where he was tutored in mathematics by Johann Bernoulli (of the famous Bernoulli family of mathematicians). He developed an interest in mathematics and eventually authored more than 700 books and papers. This paper discusses Euler's work on the solution to Diophantine equations (marking the early history of algebraic number theory), analytic number theory, arithmetic functions, and his theory of partitions. JF - Australian Mathematics Teacher AU - Len, Amy AU - Scott, Paul Y1 - 2004 PY - 2004 DA - 2004 SP - 2 EP - 5 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 1 SN - 0045-0685, 0045-0685 KW - Switzerland KW - ERIC, Current Index to Journals in Education (CIJE) KW - Algebra KW - Mathematical Logic KW - Foreign Countries KW - Equations (Mathematics) KW - Validity KW - Number Systems KW - Number Concepts KW - Mathematics KW - Biographies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62069840?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4109 4335; 7190 6396; 990 6113 7104 8371 6120 4918 5964; 402 6410 5964; 3551 6400 6403 6394; 6410 5964; 7193 7195 10407; 6403; 11210 3627 2416 10031 ER - TY - JOUR T1 - Mathematics and Literature (the Sequel): Imagination as a Pathway to Advanced Mathematical Ideas and Philosophy AN - 62069435; EJ743535 AB - This article is the sequel to the use of "Flatland" with beginning algebra students reported in Sriraman (2003). The use of "Flatland" with beginning algebra students resulted in the positive outcomes of cultivating critical thinking in the students as well as providing the teacher with the context necessary to introduce sophisticated mathematical ideas. The marriage of mathematics and literature led students to reflect on contemporary society and its problems as well as gain an insight into notions of limits, historical approximation techniques and various non-Euclidean geometries (fractal geometry and Minkowskian space-time geometry). This atypical but refreshing learning experience led students to request the reading of one of the sequels to Flatland. The release of Stewart's "Flatterland" in 2001 provided an ideal follow up to "Flatland". Banchoff's (2001) review of "Flatterland" for the Mathematical Association of America partially found in the back cover states: "Flatterland" challenges readers to go beyond "Flatland" and deal with phenomena, not just in dimensions higher than four, but in many exotic geometric realms that stretch our imagination and powers of visualization." (Contains 1 figure and 1 table.) JF - Australian Mathematics Teacher AU - Sriraman, Bharath Y1 - 2004 PY - 2004 DA - 2004 SP - 17 EP - 23 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 1 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teacher Student Relationship KW - Algebra KW - Class Activities KW - Mathematics Instruction KW - Literature KW - Discussion (Teaching Technique) KW - Learning Experience KW - Critical Thinking KW - Interdisciplinary Approach KW - Geometry KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62069435?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 402 6410 5964; 2432 1710; 5893 3685 853; 4343 6410 5964; 10576 5449 8768; 1571 9146 126; 2915 10621 3227 6582; 10621 3227 6582; 6120 4918 5964; 6419 5242; 5368 6582 ER - TY - JOUR T1 - Classroom Computer Algebra: Some Issues and Approaches AN - 62069397; EJ743543 AB - Not so long ago, the common response of teachers to high school use of computer algebra systems (CAS) was invariably along the lines of, "What will be left to teach if our students have access to devices which solve, factorise, do calculus and more?" and "If students use such tools, then they will never learn how to do their mathematics, and their algebra skills will deteriorate" and the classic cry, "What will be left for us to put into our examinations?". This article presents questions that offer ideal illustrations of the power of computer algebra as a classroom learning tool. These tools support students, not in mindlessly producing results, but in purposeful and strategic investigation of problems. JF - Australian Mathematics Teacher AU - Arnold, Stephen Y1 - 2004 PY - 2004 DA - 2004 SP - 17 EP - 21 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 2 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Algebra KW - Mathematics Instruction KW - Calculators KW - Computer Assisted Instruction KW - Mathematics Skills KW - Educational Technology KW - Teaching Methods KW - Instructional Innovation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62069397?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6419 5242; 3268 10669; 402 6410 5964; 5251 3215 5188; 1239 3553; 10621 3227 6582; 6421 9690 1; 2015 2074 2073 10675 ER - TY - JOUR T1 - Anyone for Tennis? AN - 62068788; EJ743534 AB - Tennis is a sport in which the mathematics involves an unusual scoring system together with other applications pertinent to the draw for different types of tournaments and the relative ratios of points won and lost. The name of the sport is thought to have originated from the French word "tenez", which translates roughly as "to receive (the ball)". However, there is an alternative possibility connected with the Egyptian city, Tennis, which was noted in the Middle Ages for its linen from which early tennis balls were made. This article describes mathematical exercises involving both tennis competitions and scoring. JF - Australian Mathematics Teacher AU - de Mestre, Neville Y1 - 2004 PY - 2004 DA - 2004 SP - 14 EP - 16 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 1 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Mathematics Instruction KW - Mathematics Activities KW - Mathematical Concepts KW - Scoring KW - Racquet Sports UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62068788?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6412 126; 8568 704 7840 126; 9371 6440; 6419 5242; 6396 ER - TY - JOUR T1 - Credit Card Mathematics AN - 62068747; EJ743550 AB - The history of mathematics is full of rich examples that can help students to see the place of the discipline within our cultural heritage. Valuable as this can be, it also has the unfortunate side-effect of making students think that all the math has already been done and they do not get a sense that the subject is dynamic and growing. Furthermore, most modern mathematics is very complex and not accessible to students in secondary school. This article presents a mathematical topic which is historical in the sense that it was first presented almost fifty years ago but modern because it is still used billions of times each and every day all over the world--and one that students in upper primary and lower secondary school can appreciate quite readily. (Contains 1 table.) JF - Australian Mathematics Teacher AU - Wood, Eric Y1 - 2004 PY - 2004 DA - 2004 SP - 29 EP - 33 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 2 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Secondary Education KW - Credit (Finance) KW - Computation KW - Mathematics Instruction KW - Deception KW - Mathematical Concepts KW - Error Patterns KW - Learning Activities KW - Error Correction UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62068747?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 2394; 5883 126; 6396; 3571; 3574; 2003 6394; 2648; 6419 5242 ER - TY - JOUR T1 - The Golden Ratio AN - 62068744; EJ743536 AB - The Golden Ratio is sometimes called the "Golden Section" or the "Divine Proportion", in which three points: A, B, and C, divide a line in this proportion if AC/AB = AB/BC. "Donald in Mathmagicland" includes a section about the Golden Ratio and the ratios within a five-pointed star or pentagram. This article presents two computing exercises that provide follow-up classroom activities after the class has watched "Donald in Mathmagicland". JF - Australian Mathematics Teacher AU - Hyde, Hartley Y1 - 2004 PY - 2004 DA - 2004 SP - 30 EP - 31 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 1 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Computation KW - Class Activities KW - Geometric Concepts KW - Mathematics Instruction KW - Mathematical Concepts KW - Computer Software UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62068744?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6396; 6419 5242; 2003 6394; 1571 9146 126; 4339 6396; 2059 ER - TY - JOUR T1 - Quantitative Literacy in the Media: An Arena for Problem Solving AN - 62068693; EJ743537 AB - The term "quantitative literacy" is used in this article to reinforce its importance in catering for reform-based curricula in Australia. The medium chosen for the problems discussed in this paper is the newspaper. The purpose of this article is to tie together traditional views of the importance of problem solving with the current aims of numeracy and quantitative literacy. In doing this, the author considers another angle on the development of quantitative literacy. Watson (1997) suggested a hierarchy for the related field of statistical literacy, which is easily adapted in the wider milieu. The hierarchy suggests three tiers or steps in the development of the goal of quantitative literacy: (1) The terminology needs to be understood; (2) This terminology then needs to be understood within the social (or scientific) context in which it is used; and (3) There needs to be a critical awareness that prompts questioning of claims in context that are made without proper justification. (Contains 5 figures.) JF - Australian Mathematics Teacher AU - Watson, Jane M. Y1 - 2004 PY - 2004 DA - 2004 SP - 34 EP - 40 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 1 SN - 0045-0685, 0045-0685 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Newspapers KW - Thinking Skills KW - Mass Media Use KW - Foreign Countries KW - Educational Change KW - Numeracy KW - Journal Articles KW - Media Literacy KW - Mathematics KW - Problem Solving UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62068693?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 8233 1710; 7196; 4109 4335; 6466 6101; 10852 1701 1 9690; 7073 7068 6362; 5602 8477; 6410 5964; 6366; 3176 1387 ER - TY - JOUR T1 - A Difficult Function AN - 62066651; EJ743540 AB - Technology is evolving and now some secondary classrooms see students using computer algebra systems (CAS), however, Zbiek (2003) points out that "graphical representations seem to abound in CAS-using classrooms" and "many [research] studies of the use of CAS depend highly on the graphing component of the tool". Kissane (2001) suggests that with the personal experience afforded by a graphing calculator the nature of learning "if carefully structured by the teacher, can provide pupils with important insights about functions and their graphical representations". Burrill et al. in their 2002 review note that the core research finding is that the type and extent of gains in student learning in the presence of handheld graphing technology "are a function, not simply of the presence of the graphing technology, but of how the technology is used in the teaching of mathematics". They concluded that "specific issues regarding the effective use of handheld graphing technology in the classroom have not yet been adequately addressed". This paper describes approaches used by senior secondary students using a Texas Instrument (TI) 83 graphing calculator during a small research study to determine a global view of a difficult function. Implications of these approaches for teaching in a graphing calculator environment are presented and discussed. (Contains 6 figures.) JF - Australian Mathematics Teacher AU - Brown, Jill Y1 - 2004 PY - 2004 DA - 2004 SP - 6 EP - 11 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide, South Australia 5001. Tel: +61 8 8363 0288; Fax: +61 8 8362 9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au. VL - 60 IS - 2 SN - 0045-0685, 0045-0685 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Grade 11 KW - Grade 12 KW - Secondary Education KW - Graphing Calculators KW - Algebra KW - Student Attitudes KW - Mathematics Instruction KW - Case Studies KW - Educational Technology KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62066651?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6419 5242; 3268 10669; 4484 1239 3553; 1326 3629 6582 8836; 10181 730; 4415 5264; 4416 5264; 10621 3227 6582; 402 6410 5964 ER - TY - GEN T1 - Improving Access to Assistive Technology for Individuals with Disabilities Act of 2004. House of Representatives, One Hundred Eighth Congress, Second Session (June 1, 2004). Report 108-514 AN - 62014983; ED496586 AB - The Committee on Education and the Workforce, to whom was referred the bill (H.R. 4278) to amend the Assistive Technology Act of 1998 to support programs of grants to States to address the assistive technology needs of individuals with disabilities, and for other purposes, having considered the same, report favorably thereon with an amendment and recommend that the bill as amended do pass. Sections of "Improving Access to Assistive Technology for Individuals with Disabilities Act of 2004" include: (1) Findings and purposes; (3) Definitions; (4) Grants to States for purchase of assistive technology devices and assistive technology services; (5) Grants to States for protection and advocacy related to assistive technology; (6) Administrative provisions; (7) National activities; and (8) Authorization of appropriations. Y1 - 2004 PY - 2004 DA - 2004 SP - 83 PB - US House of Representatives. Washington, DC 20515. , 732 North Capitol Street, Washington, DC 20401. KW - ERIC, Resources in Education (RIE) KW - Assistive Technology KW - Federal Legislation KW - Federal Aid KW - Disabilities KW - Grants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62014983?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - Strategies Employed by Upper Secondary Students for Overcoming or Exploiting Conditions Affecting Accessibility of Applications Tasks AN - 62012436; EJ747863 AB - A cognitive/metacognitive framework is presented for analysing applications tasks and responses to these. Conditions facilitating or impeding access to such tasks at the upper secondary level were identified using qualitative data analysis techniques within this framework. Strategies employed in exploiting, or overcoming these conditions were identified. A well-developed repertoire of cognitive and metacognitive strategies together with a rich store of mathematical knowledge, real-world knowledge and experiences, and comprehension skills facilitated access. This was enhanced by metacognitive knowledge encouraging student engagement with the task and by students imagining they were in the task situation. Once moderate skill had been achieved in accessing these applications, coordination and integration of multiple representations, further cues, and mathematical processes and procedures became critical. Examples of Application Tasks are Appended.(Contains 2 tables and 1 figure.) JF - Mathematics Education Research Journal AU - Stillman, Gloria Y1 - 2004 PY - 2004 DA - 2004 SP - 41 EP - 71 PB - Mathematics Education Research Group of Australasia. MERGA-GPO Box 2747, Adelaide, South Australia 5001, Australia. VL - 16 IS - 1 SN - 1033-2170, 1033-2170 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Grade 11 KW - Grade 12 KW - High Schools KW - Long Term Memory KW - Mathematical Models KW - Metacognition KW - Problem Solving KW - Memory KW - Foreign Countries KW - Public Schools KW - Cognitive Processes KW - Student Attitudes KW - Interviews KW - Data Analysis KW - High School Students KW - Learning Strategies KW - Mathematical Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62012436?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4738 9419 10278 8016 4542; 2574 3629 6582; 6563 1710; 6394; 1710; 8467 9306 5241; 5472 3629 6582; 5911 6582; 6404 6752 9651 6582; 10181 730; 6519 1710; 6173 6519 1710; 8233 1710; 4109 4335 ER - TY - JOUR T1 - Understanding Linear Measurement: A Comparison of Filipino and New Zealand Children AN - 62012387; EJ747865 AB - An understanding of linear measurement depends on principles that include standard unit size, iteration of units, numbering of a unit at its end, and partial units for measuring continuous length. Children may learn these principles at school, for example through experience with informal measurement, or they may learn them through use of measurement in society. This study compared the application of these principles by children aged 8 and 9 from the Philippines and New Zealand. These countries were selected because they have quite different curricula, societal influences and economies. Ninety-one children were interviewed individually on a common set of unusual tasks that were designed to tap underlying principles. Results showed many similarities and some differences between countries. Most tasks requiring visualisation and informal units were done more accurately by New Zealand children. Some tasks involving the use of a conventional ruler were done more accurately by Filipino children. These differences appear to be related to differences in curricula and possibly to differences in societal use of measurement. We suggest that these results, like those of other writers cited, demonstrate the need for extensive work on the underlying concepts in measurement through work on informal measurement and a careful transition between informal and formal measurement. (Contains 7 tables and 5 figure.) JF - Mathematics Education Research Journal AU - Irwin, Kathryn C. AU - Vistro-Yu, Catherine P. AU - Ell, Fiona R. Y1 - 2004 PY - 2004 DA - 2004 SP - 3 EP - 24 PB - Mathematics Education Research Group of Australasia. MERGA-GPO Box 2747, Adelaide, South Australia 5001, Australia. VL - 16 IS - 2 SN - 1033-2170, 1033-2170 KW - New Zealand KW - Philippines KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Childhood Attitudes KW - Comparative Analysis KW - Measurement KW - Elementary School Students KW - Socioeconomic Influences KW - Foreign Countries KW - Cultural Influences KW - Mathematics Curriculum KW - Mathematical Concepts KW - Interviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62012387?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4109 4335; 3363 10278 8016 4542; 5472 3629 6582; 6440; 1955 3629 6582; 1469 730; 2484 5127; 6396; 9833 5127; 6416 2515 ER - TY - GEN T1 - Truth Revealed: New Scientific Discoveries Regarding Mercury in Medicine and Autism. Hearing before the Subcommittee on Human Rights and Wellness of the Committee on Government Reform, House of Representatives, One Hundred Eighth Congress, Second Session (September 8, 2004) Serial No. 108-262 AN - 62010499; ED496061 AB - This purpose of this hearing was to discuss the latest scientific research regarding the use of mercury in medicine in the United States and the possible connection between these products and autism spectrum disorders. The subcommittee also discusses the need for further research to determine the biological basis of autism and how the Federal Government is working to decrease the occurrences of this health epidemic in the United States. Representative Dan Burton and chairman of the committee begins the hearing by explaining that mercury has been present in medicines dispersed widely to the public for decades. Unknown to most Americans, mercury is still present in medicines that we use every day, including eye drops, nasal spray, as well as many anti-fungal and anti-itch creams, as well as vaccines. While the pharmaceutical industry has found new ways to manufacture many medicines and vaccinations that do not require the use of mercury, three vaccines that currently remain on the mandatory pediatric vaccine schedule still contain the mercury derivative thimerosal, and those vaccines are the DTAP, which is called the diphtheria, tetanus and pertussis vaccine, the flu vaccine and hepatitis B. Now, although it has been taken out of a lot of the children's vaccines, the shelf life on many of those vaccines is pretty long. Mercury-containing vaccines are still on the shelf, even though they are not being produced. So in addition to these three vaccines that are still being produced using mercury, there are others that are on the shelf right now that doctors are still using that children are being vaccinated with. The contents of this document include: (1) Hearing held on September 8, 2004; (2) Statements; and (3) Letters, statements, etc. submitted for the record. Y1 - 2004 PY - 2004 DA - 2004 SP - 326 PB - US House of Representatives. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - ERIC, Resources in Education (RIE) KW - Public Health KW - Scientific Research KW - Hazardous Materials KW - Immunization Programs KW - Hearings KW - Child Health KW - Federal Government KW - Medicine KW - Dentistry KW - Autism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62010499?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - Teaching Mathematics Thematically: Teachers' Perspectives AN - 62009900; EJ747861 AB - Teaching mathematics through themes has been praised for relating mathematics to real-life situations. However, research shows that the implementation of teaching mathematics thematically has not been widely adopted. In the present study, instructional, curricula and organisational factors that teachers perceive as obstacles to the implementation of a thematic approach to teaching mathematics were explored. Findings from interviews with 10 secondary mathematics teachers who were implementing a curriculum requiring a thematic instructional approach are reported. The findings of the study extend the literature concerning teachers' beliefs and practices in the teaching of mathematics, and broaden understandings of the issues surrounding the implementation of a thematically taught mathematics curriculum. Sample Items of the Questionaire and Sample Questions from the Interview are Appended. JF - Mathematics Education Research Journal AU - Handal, Boris AU - Bobis, Janette Y1 - 2004 PY - 2004 DA - 2004 SP - 3 EP - 18 PB - Mathematics Education Research Group of Australasia. MERGA-GPO Box 2747, Adelaide, South Australia 5001, Australia. VL - 16 IS - 1 SN - 1033-2170, 1033-2170 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Secondary Education KW - Questionnaires KW - Curriculum Development KW - Foreign Countries KW - Thematic Approach KW - Mathematics Instruction KW - Teacher Attitudes KW - Mathematics Teachers KW - Teacher Response KW - Secondary School Mathematics KW - Interviews KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62009900?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4109 4335; 6419 5242; 10482 730; 10823 10621 3227 6582; 5472 3629 6582; 6422 10591 8267 3417 8016 4542 5703 4908 8917; 9417 9414 2515 6416; 2521 3184 2787; 8535 6447; 10560 10486 909 8930; 10621 3227 6582 ER - TY - JOUR T1 - Towards the Modelling of Mathematical Metacognition AN - 62009841; EJ747867 AB - Metacognition has been accorded a role in both mathematical problem solving and in the learning of mathematics. There has been consistent advocacy of the need for the promotion of metacognitive activity in both domains. Such advocacy can only be effective if the advocated process is well understood. In this paper we have four goals: to describe a "multi-method" technique developed to study student mathematical metacognition; to set out the structural elements and configuration of a coherent model of metacognition in the domain of mathematical problem solving; to report on the empirical utility (and validity) of this model; and, to report the insights into student mathematical metacognition arising from the research. Multi-Method Interview Tasks are appended. (Contains 4 figures.) JF - Mathematics Education Research Journal AU - Wilson, Jeni AU - Clarke, David Y1 - 2004 PY - 2004 DA - 2004 SP - 25 EP - 48 PB - Mathematics Education Research Group of Australasia. MERGA-GPO Box 2747, Adelaide, South Australia 5001, Australia. VL - 16 IS - 2 SN - 1033-2170, 1033-2170 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Grade 6 KW - Performance Based Assessment KW - Mathematical Models KW - Research Methodology KW - Learning Processes KW - Psychometrics KW - Metacognition KW - Measurement Techniques KW - Mathematics KW - Problem Solving KW - Foreign Countries KW - Evaluation Research KW - Interviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62009841?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6563 1710; 8233 1710; 6410 5964; 4423 5264; 5472 3629 6582; 4109 4335; 8852 6582; 6446 6582; 6404 6752 9651 6582; 5904 1710; 8423 8422 926 9351 5964; 3633 6584 8836; 7705 428 3626 ER - TY - GEN T1 - Improved Monitoring of Vulnerable Children. Hearing before the Subcommittee on Human Resources of the Committee on Ways and Means, U.S. House of Representatives, One Hundred Eighth Congress, First Session (November 19, 2003) Serial No. 108-29 AN - 62009559; ED496035 AB - This hearing focused on: (1) what data States collect to monitor the care and supervision of children in foster care and children for whom adoption subsidies are paid; (2) how that data is used today; and (3) what additional data or applications of these data might better ensure the safety, permanency, and well-being of children. Testimony was heard from: Cornelia Ashby, Director, Education, Workforce and Income Security Issues, U.S. General Accounting Office; Fred H. Wulczyn, Chapin Hall Center for Children, University of Chicago; Robert McKeagney, Child Welfare League of America; David R. Springett, Community College Foundation; Tom Delay (R-TX) and House Majority Leader; Michael A. Watkins, Florida Department of Children and Families; and Jill Baker, Norfolk Department of Human Services. Twenty-two public witnesses submitted statements for the record. Y1 - 2004 PY - 2004 DA - 2004 SP - 115 PB - US House of Representatives. Washington, DC 20515. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - ERIC, Resources in Education (RIE) KW - Information Systems KW - At Risk Persons KW - State Action KW - Well Being KW - Automation KW - Adoption KW - Caseworkers KW - Federal Government KW - Accountability KW - Children KW - Child Welfare KW - Foster Care KW - State Regulation KW - Child Safety KW - Program Improvement KW - Hearings KW - Federal State Relationship KW - Data Analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62009559?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - Are Different Students Expected to Learn Norms Differently in the Mathematics Classroom? AN - 62008533; EJ747862 AB - We analyse social interactions during the first days of class in a secondary mathematics classroom (15 and 16-year-olds) with a high percentage of immigrant students. Our analyses show the co-existence of different models for both the interpretation and the use of classroom social norms and socio-mathematical norms. Valorising some behaviours over others appears as part of the discursive practices of mathematics classrooms. Local and immigrant students are not expected to behave in the same way, nor are they treated in the same way. The teacher and some students, who are familiar with the prevailing norms, cancel certain norms for a while in such a way that some immigrant students are excluded from fully participating in the mathematical discussion. JF - Mathematics Education Research Journal AU - Planas, Nuria AU - Gorgorio, Nuria Y1 - 2004 PY - 2004 DA - 2004 SP - 19 EP - 40 PB - Mathematics Education Research Group of Australasia. MERGA-GPO Box 2747, Adelaide, South Australia 5001, Australia. VL - 16 IS - 1 SN - 1033-2170, 1033-2170 KW - Spain (Barcelona) KW - ERIC, Current Index to Journals in Education (CIJE) KW - High Schools KW - Classroom Environment KW - Mathematics Instruction KW - Social Behavior KW - Immigrants KW - Student Diversity KW - Urban Schools KW - Secondary School Mathematics KW - Foreign Countries KW - Data Collection KW - Behavior Standards KW - Interpersonal Relationship KW - High School Students UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62008533?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4109 4335; 4738 9419 10278 8016 4542; 9417 9414 2515 6416; 5449 8768; 4985 6671 8016 4542; 918 10031; 9738 909; 6419 5242; 2577 5150 5159 9556 2574 3629 6582; 1604 3190 3518; 11182 9306 5241; 10197 2472 2842 10187 ER - TY - GEN T1 - Bogus Degrees and Unmet Expectations: Are Taxpayer Dollars Subsidizing Diploma Mills? Hearings before the Committee on Governmental Affairs, United States Senate, One Hundred Eighth Congress, Second Session (May 11 and 12, 2004) S. Hrg. 108-553 AN - 62006452; ED496044 AB - The purpose of these hearings was to explore the problems that unaccredited, substandard colleges and universities, often referred to as diploma mills, pose to the Federal Government and to private-sector employers. The schools examined during these hearings practice a sophisticated form of deception and they charge students accordingly. All of the schools we investigated gave credit for prior work or life experience, even for advanced degrees, which is very rare among accredited institutions. One institution's list of life experiences that could qualify for academic credit included horseback riding, playing golf, pressing flowers, serving on a jury, and planning a trip. The schools examined also required their students to do some modicum of work, either tests or papers or both, and they at least give the impression that the school includes professors with suitable academic credentials who actually play a role in the school's academic programs. The danger of these more sophisticated diploma mills is that they can attract a far broader range of students. The schools investigated take pains to try to convince prospective students that they are legitimate and that students have to earn their degrees. That is why a healthy dose of credit for work and life experience becomes such a critical component of their business model. That is what permits these more sophisticated diploma mills to assume an air of legitimacy while minimizing the actual amount of work required. During the two days of these hearings, the focus was on the challenges posed by diploma mills to the Federal Government. Opening statements at the hearings were provided by: Senators Collins; Akaka; Lautenberg; Carper; Durbin; Lieberman; and Pryor. Witnesses provided testimonies and prepared statements on both days of the hearings. An appendix presents: (1) memorandum dated April 15, 2004; and (2) questions and responses for the record from various participants. (Contains 31 exhibits.) Y1 - 2004 PY - 2004 DA - 2004 SP - 198 PB - US Senate. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - United States KW - ERIC, Resources in Education (RIE) KW - Higher Education KW - Salesmanship KW - Federal Aid KW - Exhibits KW - Federal Government KW - College Credits KW - Credentials KW - Academic Degrees KW - Tax Allocation KW - Accreditation (Institutions) KW - Institutional Evaluation KW - Deception KW - Experiential Learning KW - Recreational Activities KW - Hearings KW - Credibility KW - Academic Standards KW - Prior Learning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62006452?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - Abstinence Education. Hearing before a Subcommittee of the Committee on Appropriations, United States Senate, One Hundred Eighth Congress, Second Session (February 16, 2004). Senate Hearing 108-385 AN - 62006399; ED496065 AB - The focus of this hearing was on funding for abstinence education. Following an opening statement by Subcommittee Chairman Senator Arlen Specter of Pennsylvania, witness testimonies were heard from: Dr. Wade F. Horn, Ph.D., Assistant Secretary for Children and Families, Department of Health and Human Services, Washington, D.C.; Rev. Kenneth Page, Pastor, Great Island Presbyterian Church, Lock Haven, Pennsylvania; Dominique Urrutia, Program Coordinator, Abstinence is BEST Program, Harrisburg, Pennsylvania; Joe Fay, Executive Director, Pennsylvania Coalition to Prevent Teen Pregnancy; Kelly Lesh, Abstinence Education Special Initiative Coordinator, Heartbeat Community Service, Millerstown, Pennsylvania; Ronald Evans, Director, Bridge Youth Services, Pennsylvania; Tyler Barth, Performer, Abstinence Group Choice Initiative, Central Mountain High School, Mill Hall, Pennsylvania; Miranda Shipley, Volunteer, Peer Education, Reel Commitment Program, Fairfield, Pennsylvania; Nelly Torres, Peer Educator, Impact Group, Millersville University, Millersville, Pennsylvania; Sierra Leiphart, Volunteer, Human Life Services, York County, Pennsylvania; Jennifer Bruno, Board Member, Youth as Resources Program, Lehigh Valley High School, Bethlehem, Pennsylvania; and Jesse Walton, Staff Member, Boys to Men Program, Mercy Hospital, Pittsburgh, Pennsylvania. Y1 - 2004 PY - 2004 DA - 2004 SP - 40 PB - US Senate. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - District of Columbia KW - Pennsylvania KW - United States KW - Washington KW - Minnesota KW - Personal Responsibility and Work Opp Recon Act KW - ERIC, Resources in Education (RIE) KW - Elementary Secondary Education KW - High Risk Students KW - Volunteers KW - Depression (Psychology) KW - Coordinators KW - Grants KW - Early Adolescents KW - Suicide KW - Sex Education KW - Pregnancy KW - Sexuality KW - Human Services KW - Prevention KW - Federal Legislation KW - Contraception KW - Sexually Transmitted Diseases KW - Peer Influence KW - Hearings KW - High School Students KW - Adolescents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62006399?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - Labor, Health, and Education Issues in the State of Hawaii. Hearing before a Subcommittee of the Committee on Appropriations, United States Senate, One Hundred Eighth Congress, Second Session (Special Hearing, February 18, 2004, Honolulu, Hawaii) S. Hrg. 108-392 AN - 62004359; ED496031 AB - The purpose of this hearing was to gather information and hear testimony on three issues: (1) the expansion of the Cancer Research Center in Hawaii; (2) the recently granted legislative authority for Hawaii 3R's to utilize monies in the Native Hawaiian Education funds to repair those public schools to 25 percent or more Native Hawaiian children; and (3) the need to expand certified apprenticeship and journeymen training programs to ensure that we have qualified, homegrown tradesmen and women to meet the demand that will come as a result of the privatization of military housing. Statements were presented by: Senator Daniel K. Inouye; Senator Daniel K. Akaka; Dr. Evan S. Dobelle, president, University of Hawaii; Dr. Carl Vogel, director, Cancer Research Center of Hawaii; Ms. Dew-Anne Langcoan, vice president, Hawaii Pacific Health; Dr. Okamoto, president and CEO, the Queen's Health Systems; Dr. Jonathan K. Cho, a practicing community oncologist; Honorable Ed Case, U.S. Representative from Hawaii; Patricia Hamamoto, superintendent, State of Hawaii Department of Education; Bruce A. Coppa, Chair, Hawaii 3R's Program; Dennis Manalili, principal, Kaimuki High School; Neil Abercrombie, U.S. Representative from Hawaii; Linda Lingle, Governor, State of Hawaii; Donna Kim, vice president, Hawaii State Senate; and Sylvia J. Luke, vice speaker, Hawaii State House of Representatives; Dr. Clyde M. Sakamoto, chancellor, Maui Community College; Ramsey R. Pedersen, chancellor, Honolulu Community College; Lance Inouye, past president, General Contractors Association of Hawaii; Randy Lau, past president, Building Industry Association; Ron Taketa, United Brotherhood of Carpenters and Joiners, Local 745; Lynn Kinney, Painters, Decorators, Paperhangers and Allied Traders, Local 1791; Glaziers Architectural and Glass Metal Workers Local 1889, AFL-CIO; Hawaii Building and Construction Trades Council; Laborers' Union, Local 368; and Hawaii Operating Engineers J.A.C. Further prepared statements were submitted by: International Association of Heat & Frost Insulators & Asbestos Workers Local 132, Hawaii; Bricklayers & Ceramic Tile Setters Local 1 and Plasterers' & Cement Masons' Local 630; International Brotherhood of Electrical Workers, Local 1186, Hawaii; Boilermakers, Iron Shipbuilders Union, Local 204; Roofers, Waterproofers & Allied Workers United Union of Roofers, Local 221; United Association of Plumbers and Fitters Local 675; Scott Y. Nishimoto, State of Hawaii Representative, District 21; Pacific Resource Partnership; Americas Promise Hawaii; Joint Venture Education Forum; Drywall Tapers and Finishers Local 1944, AFL-CIO; Carpet Linoleum and Soft Tile Local 1926, AFL-CIO; CRTC, Inc; Iron Workers Local 625 and Iron Workers Shopmen Local 803; John A. Burns School of Medicine, University of Hawaii; University of Hawaii at Manoa; Joseph Kane, Jr.; and Sheet Metal Workers Union Local 293. Y1 - 2004 PY - 2004 DA - 2004 SP - 200 PB - US Senate. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - Hawaii KW - United States KW - ERIC, Resources in Education (RIE) KW - Adult Education KW - Elementary Secondary Education KW - Educational Facilities KW - Housing KW - Unions KW - Hawaiians KW - Privatization KW - Federal Government KW - Medical Schools KW - Oncology KW - Laborers KW - Job Training KW - Maintenance KW - Cancer KW - Supply and Demand KW - Human Capital KW - Apprenticeships KW - Public Schools KW - Federal Programs KW - Military Personnel KW - Skilled Workers KW - Hearings KW - Metal Working KW - Community Colleges KW - Labor Supply UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62004359?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - Palestinian Education--Teaching Peace or War? Hearing before a Subcommittee of the Committee on Appropriations, United States Senate, One Hundred Eighth Congress, First Session (October 30, 2003) S. Hrg. 108-290 AN - 62003423; ED496034 AB - The focus of this hearing was on the issues of education of Palestinian young people, funding by the U.S. Government for the Palestinian Authority, and the implications on the Mid-East peace process. Opening statements were presented by Subcommittee Chairman Senator Arlen Specter, Pennsylvania; and Senator Hillary Rodham Clinton, New York. Witness testimonies and prepared statements were presented from: Itamar Marcus, Director, Palestinian Media Watch; the Honorable Mr. David Satterfield, Deputy Assistant Secretary of State for Near Eastern Affairs; James Kunder, Deputy Assistant Administrator for Asia and Near Eastern Affairs and Director of Afghan Relief and Reconstruction, USAID; Richard Solomon, President, U.S. Institute of Peace (accompanied by Steven Riskin, Program Officer, Grant Program, U.S. Institute of Peace); Dr. Hassan Abdel Rahman, Chief Representative, PLO Mission; Ziad Asali, President, American Task Force on Palestine; and Dr. Morton Klein, President, Zionist Organization of America. An additional submitted statement from The American Jewish Committee is also included as part of the hearing record. (Contains 8 footnotes.) Y1 - 2004 PY - 2004 DA - 2004 SP - 74 PB - US Senate. Washington, DC 20510. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - Palestine KW - United States KW - ERIC, Resources in Education (RIE) KW - Elementary Secondary Education KW - Foreign Countries KW - War KW - Legislators KW - Educational Finance KW - Arabs KW - Grants KW - Hearings KW - Peace KW - Foreign Policy KW - Jews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62003423?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - To Review Federal and State Oversight of Child Welfare Programs. Hearing before the Subcommittee on Human Resources of the Committee on Ways and Means, U.S. House of Representatives, One Hundred Eighth Congress, Second Session (January 28, 2004). Serial Number 108-30 AN - 62001791; ED496059 AB - The focus of this hearing is to review Federal and State oversight of child welfare programs and systems designed to prevent abuse and neglect of children, including those under State protection. The purpose being to provide subcommittee representatives the opportunity to learn what Federal, State, and local officials should be doing to ensure that children are in safe, loving environments. Oral testimony at this hearing is both invited and public witnesses. Invited witnesses include Federal and State officials and other experts familiar with child welfare programs. This document commences with Advisory of January 21, 2004, announcing the hearing. Testimonies from the following witnesses are then provided: U.S. Department of Health and Human Services, Honorable Wade F. Horn, Ph.D., Assistant Secretary for Children and Families; and U.S. General Accounting Office, Cornelia M. Ashby, Director, Education, Workforce, and Income Security Issues. Additional testimonies are provided by witnesses: Alliance for Children and Families, Curtis C. Mooney; Association on American Indian Affairs, Jack F. Trope; Thomas C. Atwood, National Council For Adoption; William C. Bell, New York City Administration for Children's Services; Shay Bilchik, Child Welfare League of America; Thomas L. Birch, National Child Abuse Coalition; Cathy Burge, Naples, Florida; Catholic Charities, Archdiocese of New York, Monsignor Kevin Sullivan; Honorable William Frenzel, Pew Commission on Children in Foster Care; Lisa E. Gladwell, River Edge, New Jersey; Courteney Anne Holden, Voice For Adoption; Home School Legal Defense Association, Christopher J. Klicka; Iowa Department of Human Services, Division of Behavioral, Developmental, and Protective Services for Families, Adults, and Children, Mary J. Nelson; National Association of Foster Care Reviewers, Bill Stanton; Marie C. O'Hara, Barnegat, New Jersey; Pennsylvania Department of Public Welfare, Office of Children, Youth, and Families, Wayne T. Stevenson. Submissions for the record are then provided by: Edith J. Beauchamp, Greenbelt, Maryland; Patricia de Santos, Claremont, California; Judith G. Evans-Baxter, Pompano Beach, Florida; and Voice Application Specialists International, Inc., Woodstock, Georgia, Maricriz Nolan. Y1 - 2004 PY - 2004 DA - 2004 SP - 154 PB - US House of Representatives. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - ERIC, Resources in Education (RIE) KW - Legislators KW - Delivery Systems KW - Background KW - Welfare Services KW - Benchmarking KW - Human Resources KW - Accountability KW - Child Welfare KW - Child Safety KW - Human Services KW - Position Papers KW - Federal Legislation KW - Hearings KW - Information Management KW - Child Abuse KW - Audits (Verification) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62001791?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - Ethnomathematical Ideas in the Curriculum AN - 62001478; EJ747868 AB - A study was undertaken to investigate the implementation of an ethnomathematical unit in a mathematics classroom in the Maldives. The research was conducted during the first four months of 2002 at two primary schools and involved teaching grade 5 students an ethnomathematical unit of work on measurement. The unit was designed in conjunction with the teachers. In this article ethnomathematical curriculum models are discussed and the approach used in the study is described. Data are presented indicating teachers' and students' reactions to using such a curriculum unit. The data showed that despite the very traditional education of the Maldives, the ethnomathematical approach was appreciated and understood by teachers and students. (Contains 2 figures.) JF - Mathematics Education Research Journal AU - Adam, Shehenaz Y1 - 2004 PY - 2004 DA - 2004 SP - 49 EP - 68 PB - Mathematics Education Research Group of Australasia. MERGA-GPO Box 2747, Adelaide, South Australia 5001, Australia. VL - 16 IS - 2 SN - 1033-2170, 1033-2170 KW - Maldives KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Grade 5 KW - Measurement KW - Cultural Context KW - Program Effectiveness KW - Culturally Relevant Education KW - Classroom Environment KW - Units of Study KW - Models KW - Educational Environment KW - Foreign Countries KW - Experiential Learning KW - Mathematics Curriculum KW - Mathematical Concepts KW - Teaching Styles KW - Mathematics Teachers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62001478?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 8299; 4109 4335; 4422 5264; 6752 9651 6582; 3190 3518; 6416 2515; 6422 10591 8267 3417 8016 4542 5703 4908 8917; 2471 3518; 1604 3190 3518; 10631 10492 10486 909; 6396; 11129 2351 2515; 3692 5882; 6440; 3352 3368 3150; 2501 3150 8774 2494 ER - TY - GEN T1 - Vocational and Technical Education for the Future Act. Report Together with Additional Views. U.S. House of Representatives, One Hundred Eighth Congress, Second Session (September 7, 2004). Report 108-659 AN - 62000479; ED496589 AB - H.R. 4496, the Vocational and Technical Education for the Future Act, strengthens and improves the Carl D. Perkins Vocational and Technical Education Act by enhancing local accountability, introducing model sequences of courses that incorporate both secondary and postsecondary elements in a non-duplicative progression of courses, and merging the stand-alone Tech-Prep program with the Basic State Grant program. The bill reauthorizes the Act through 2010. Y1 - 2004 PY - 2004 DA - 2004 SP - 104 PB - US House of Representatives. Washington, DC 20515. , 732 North Capitol Street, Washington, DC 20401. KW - Carl D Perkins Vocational Technical Educ Act 1998 KW - ERIC, Resources in Education (RIE) KW - Postsecondary Education KW - Secondary Education KW - Federal Legislation KW - Federal Aid KW - Educational Legislation KW - Grants KW - Tech Prep KW - Vocational Education KW - Accountability KW - Technical Education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62000479?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - RPRT T1 - Private and Public Contributions to Financing College Education. A CBO Paper AN - 62000060; ED496553 AB - The cost of four years of undergraduate education, including living expenses, now averages nearly $80,000 at public colleges and over $100,000 at many private institutions. Tuition and fees have risen steadily since 1980, fueling concern that college is becoming prohibitively expensive for many families. This Congressional Budget Office (CBO) paper--prepared at the request of the Senate Budget Committee--estimates how much students and families paid in college costs in the 1999-2000 academic year after accounting for all of that aid. Because a primary purpose of financial aid is to level the playing field among students and because the cost of college differs significantly for different types of institutions (for example, two-year public and four-year private schools), CBO breaks down its estimates by family income group and type of college. Several findings from CBO's analysis suggest that governmental and other nonfamily assistance makes up a particularly large share of financial support for students from low-income families. Reconciling Means of Financing with Tuition and Nontuition Expenditures is appended. (Contains 12 tables, 4 figures, and 15 footnotes.) AU - Alsalam, Nabeel AU - Giertz, Seth Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 36 PB - Congressional Budget Office. Ford House Office Building, 4th Floor, Second and D Streets SW, Washington, DC 20515-6925. KW - ERIC, Resources in Education (RIE) KW - Higher Education KW - Financial Support KW - Low Income Groups KW - Student Loan Programs KW - Federal Aid KW - Undergraduate Study KW - Grants KW - Educational Finance KW - Public Colleges KW - Tuition KW - State Aid KW - Student Financial Aid KW - Paying for College KW - Family Income KW - Private Schools KW - Student Costs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62000060?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - Oversight Hearing on Section 529 College Savings Plans: High Fees, Inadequate Disclosure, Disparate State Tax Treatment, and Questionable Broker Sales Practices. Hearing before the Financial Management, the Budget, and International Security Subcommittee of the Committee on Governmental Affairs, United States Senate, One Hundred Eighth Congress, Second Session (September 30, 2004) S. Hrg. 108-716 AN - 61999677; ED496033 AB - The Subcommittee conducted an oversight hearing on Section 529 College Savings Plans, State-sponsored investments that are designed to encourage families to save money for their children's college education. Section 529 refers to the Internal Revenue Code section that authorizes and confers special tax treatment on these entities. Section 529 College Savings Plans are instrumentalities of the various State Governments. The States usually organize the plans as trusts which, in turn, typically invest the plan assets in mutual funds managed by third party asset managers. This oversight hearing built on two previous hearings in which this Subcommittee examined mutual fund management and governance, mutual fund fees, and the adequacy of fee disclosures. Testimony was presented by: Senator Peter G. Fitzgerald (R-IL); Senator Frank Lautenberg (D-NJ); Senator Mark Pryor (D-AR); Senator Daniel K. Akaka (D-Hawaii); Steven T. Miller, Commissioner, Tax Exempt and Government Entities Division, Internal Revenue Service; Mary L. Schapiro, Vice Chairman and President, Regulatory Policy and Oversight, NASD; Ernesto A. Lanza, Senior Associate General Counsel, Municipal Securities Rulemaking Board; Michael A. Ablowich, Treasurer, State of New Hampshire, on behalf of the National Association of State Treasurers; Jacqueline T. Williams, Executive Director, College Advantage Savings Plan, Ohio Tuition Trust Authority, on behalf of the College Savings Plan Network; Martin M. Noven, Deputy Chief of Staff, on behalf of Judy Baar Topinka, State Treasurer, State of Illinois; Richard O. Davis, Deputy Executive Director for Finance and Administration, Utah Higher Education Assistance Authority; Daniel McNeela, CFA, Senior Analyst, Morningstar, Inc.; and Mercer E. Bullard, President and Founder, Fund Democracy, Inc. Appendices includes a chart entitled "Value of a $10,000 investment after 10 years"; a chart entitled "Value of a $10,000 investment after 18 years"; a chart entitled "Growth in Section 529 Plans 1996-2004"; The "529 Plan Information" chart from the Morningstar website; Barbara Hafer, Treasurer, Commonwealth of Pennsylvania, prepared statement with an attachment; Tim Berry, Indiana State Treasurer and NAST President, National Association of State Treasurers; and Questions and Responses to Senator Lautenberg from Mr. Miller, Mr. Lanza, Ms. Schapiro, Mr. McNeela, and Mr. Bullard. Y1 - 2004 PY - 2004 DA - 2004 SP - 200 PB - US Senate. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - Internal Revenue Code KW - Illinois KW - New Hampshire KW - Ohio KW - United States KW - Utah KW - ERIC, Resources in Education (RIE) KW - Higher Education KW - State Programs KW - Salesmanship KW - Educational Finance KW - Federal Government KW - Disclosure KW - Income KW - Fees KW - Taxes KW - Money Management KW - Paying for College KW - Ethics KW - Hearings KW - Investment KW - Trusts (Financial) KW - Federal State Relationship UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61999677?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - Maintaining a Level Playing Field for DC Graduates: Legislation to Reauthorize the DC College Access Act. Hearing before the Committee on Government Reform, House of Representatives, One Hundred Eighth Congress, Second Session (March 25, 2004) Serial No. 108-172 AN - 61996991; ED496038 AB - This hearing was convened to discuss the reauthorization of the District of Columbia Tuition Assistance Grant Program. The purpose of the hearing was to highlight the tremendous impact the tuition assistance program has had on promoting higher education for high school graduates in the Nation's Capital. The original aim of the program in 1999 was to provide DC high school graduates the same opportunity that college bound seniors in each of the 50 States have, specifically a network of State supported institutions to attend at a relatively low cost. The program sought to level the playing field for DC residents who do not have access to a similar State supported system. To accomplish this, the Tuition Assistance Grant Program covers the difference between in State and out of State tuition rates for District high school graduates at public colleges and universities throughout the Nation. The program also provides limited financial assistance to DC high school graduates attending private schools in the DC metropolitan area as well as students who attend private historically Black colleges and universities in other States. Statements were heard from: Kelly Valentine, acting director, District of Columbia Tuition Assistance Grants Program; Argelia Rodriguez, executive director, District of Columbia College Access Program; Brian L. Ford, former DC TAG recipient; Anthony Talley, director of guidance and counseling, Washington Math Science Technology Public Charter High School; and Anthony A. Williams, Mayor, District of Columbia. Letters and statements were also presented for the record by: Chairman Tom Davis, a Representative in Congress from the State of Virginia; and Brian L. Ford, former DC TAG recipient. Y1 - 2004 PY - 2004 DA - 2004 SP - 71 PB - US House of Representatives. , S. Government Printing Office, 732 N. Capitol Street, Washington, DC 20401. KW - District of Columbia KW - ERIC, Resources in Education (RIE) KW - High Schools KW - Higher Education KW - High School Graduates KW - Black Colleges KW - Educational Finance KW - Grants KW - Public Colleges KW - Tuition KW - Federal Legislation KW - Hearings KW - Metropolitan Areas KW - Private Schools KW - Educational Technology KW - State Colleges UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61996991?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - A Developmental Scale of Mental Computation with Part-Whole Numbers AN - 61996432; EJ747869 AB - In this article, data from a study of the mental computation competence of students in grades 3 to 10 are presented. Students responded to mental computation items, presented orally, that included operations applied to fractions, decimals and percents. The data were analysed using Rasch modelling techniques, and a six-level hierarchy of part-whole computation was identified. This hierarchy is described in terms of the three different representations of part-whole reasoning--fraction, decimal, and percent--and is elaborated by a consideration of the likely cognitive demands of the items. Discussion includes reasons for the relative difficulties of the items, performance across grades and directions for future research. (Contains 2 tables and 3 figures.) JF - Mathematics Education Research Journal AU - Callingham, Rosemary AU - Watson, Jane Y1 - 2004 PY - 2004 DA - 2004 SP - 69 EP - 86 PB - Mathematics Education Research Group of Australasia. MERGA-GPO Box 2747, Adelaide, South Australia 5001, Australia. VL - 16 IS - 2 SN - 1033-2170, 1033-2170 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Secondary Education KW - Elementary School Students KW - Measures (Individuals) KW - Competence KW - Secondary School Students KW - Models KW - Arithmetic KW - Cognitive Processes KW - Foreign Countries KW - Mental Computation KW - Mathematics Curriculum KW - Mathematics Tests KW - Mathematical Concepts KW - Performance KW - Age Differences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61996432?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6529 2003 6394 1710; 1970 1; 610 6410 5964; 6396; 7701 909; 4109 4335; 6752 9651 6582; 6447; 3363 10278 8016 4542; 9419 10278 8016 4542; 6416 2515; 6423 10789 6447; 1710; 312 5054 2842 ER - TY - JOUR T1 - 30 Track Games for Young Children AN - 61925481; EJ793885 AB - Whenever teachers of young children get together there will be differences of opinion about how far children should be taught to count. Some will argue that the focus should be on small numbers to 9, building up the notion of what, say, the name 5 means, what it looks like, and how it can be represented. Others argue that with ice blocks retailing at $1.35 each, it is more important for children to be exposed to two and three-digit numbers so that they can figure out how these bigger numbers operate. Development of number knowledge is further inhibited by the absence of the 1 and 2-cent coins that used to be countable items. Everybody knows that for many children, counting forms the basis for early numerical problem solving, but there is perhaps a need for balanced, simultaneous development of one and two-digit numbers, so that children learn small numerosity at the same time as beginning to appreciate how the larger number system works. In this article, the authors explain how the 30 Track, a metre-long device with 30 blocks that rotate to reveal the corresponding numerals, has the potential to facilitate the learning of number and counting skills in young children. (Contains 1 figure.) JF - Australian Primary Mathematics Classroom AU - Bell, Garry AU - Henderson, Colleen Y1 - 2004 PY - 2004 DA - 2004 SP - 19 EP - 24 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 2 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Mathematical Models KW - Mathematics Instruction KW - Young Children KW - Number Systems KW - Manipulative Materials KW - Arithmetic KW - Foreign Countries KW - Educational Games KW - Visual Aids KW - Mathematics Activities KW - Mathematics Teachers KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61925481?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7193 7195 10407; 11655 1474 316 8016 4542; 610 6410 5964; 6419 5242; 6422 10591 8267 3417 8016 4542 5703 4908 8917; 10621 3227 6582; 8179 3352 3368 3150 3085; 4109 4335; 6296 5258 3224; 6404 6752 9651 6582; 11302; 6412 126; 3206 4270 126 ER - TY - JOUR T1 - Mathematics Games with the Alphabet AN - 61925435; EJ793895 AB - Sometimes the first step towards making a new (mathematics) game is discovering an unexpected possibility in some hitherto unplayed-with piece of equipment. At other times the first step is inventing new equipment. But rarely is any "new" idea for a game wholly original, either as a way of playing a game, or in its equipment. As letter-based word games, "Cross Words", "Hang the Butcher" and the great classic word-spelling game "Scrabble are familiar"; but what else might teachers do with alphabet letters? In this article, the author makes the ordinary fascinating as he piques everybody's curiosity about the origins of the alphabet and turns the various mathematical properties of letters into bases for games. JF - Australian Primary Mathematics Classroom AU - Gough, John Y1 - 2004 PY - 2004 DA - 2004 SP - 22 EP - 26 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 3 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Orthographic Symbols KW - Foreign Countries KW - Mathematics Instruction KW - Reading Instruction KW - Educational Games KW - Teaching Methods KW - Mathematics KW - Alphabets UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61925435?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 3206 4270 126; 423; 7438 11641 5746; 8646 5242; 4109 4335; 6419 5242; 6410 5964; 10621 3227 6582; 8179 3352 3368 3150 3085 ER - TY - JOUR T1 - Supporting Indigenous Students' Achievement in Numeracy AN - 61924278; EJ793954 AB - In this article, the authors report on a state project designed to explore numeracy outcomes of Indigenous students. The "Supporting Indigenous students achievement in numeracy" project (2003-2004), commissioned by Education authorities in the Northern Territory, was aimed at researching the impact of the development and implementation of authentic (rich) assessment tasks on the numeracy outcomes of middle years Indigenous students in a targeted group of remote, non-urban schools. The project involved the schools in trialing and/or implementing a range of rich tasks aimed at identifying starting points for numeracy teaching. Results indicated that students in the target group found the "rich" tasks difficult to access, even though a concerted attempt had been made to ensure that the tasks were relevant and the literacy demands were kept to a minimum. It was also evident that there was considerable variation in task administration both within and between schools. This has important implications for the wider use of these types of tasks and suggests that much more work is needed to ensure equity of access across very different communities. Another extremely important outcome of this project was the reported growth in teacher knowledge and confidence about how to teach mathematics more effectively to students in remote, non-urban communities. (Contains 3 figures.) JF - Australian Primary Mathematics Classroom AU - Siemon, Dianne AU - Enilane, Fran AU - McCarthy, Jan Y1 - 2004 PY - 2004 DA - 2004 SP - 50 EP - 53 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Elementary School Mathematics KW - Indigenous Populations KW - Culturally Relevant Education KW - Foreign Countries KW - Cultural Influences KW - Mathematics Instruction KW - Rural Schools KW - Minority Group Children KW - Numeracy KW - Mathematics Achievement KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61924278?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7196; 6411 96; 5046 8016 4542; 4109 4335; 9061 9306 5241; 10621 3227 6582; 6419 5242; 3360 6416 2515 3357; 6712 1474 316 8016 4542; 2484 5127; 2501 3150 8774 2494 ER - TY - JOUR T1 - Ability Groups: Ineffective on Ineffectively Used? AN - 61921936; EJ793889 AB - All teachers are aware of the wide range of abilities that exist within most standard Australian primary school classrooms. Many of these schools implement structures such as ability grouping and/or streaming to help meet the needs of this diverse group of learners; but does ability grouping meet these needs? The number of studies that have looked at the pros and cons of ability grouping is overwhelming, and they conclusively prove one thing, that the research is inconclusive. Working as a student services officer teaching mathematics to small ability groups has prompted the author to consider his own perspectives on this topic, and more importantly to consider how he can make this type of instruction more effective. This article looks at the justification for maintaining small ability groups and the implications to achieving success. JF - Australian Primary Mathematics Classroom AU - Scholz, Simon Y1 - 2004 PY - 2004 DA - 2004 SP - 29 EP - 31 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 2 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Instructional Effectiveness KW - Inclusive Schools KW - Foreign Countries KW - Mathematics Instruction KW - Mathematical Concepts KW - Classrooms KW - Ability Grouping KW - Outcomes of Education KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61921936?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 2 4831 4540 1595 7404; 1620 3199 3760; 6419 5242; 10621 3227 6582; 4109 4335; 8179 3352 3368 3150 3085; 6396; 5018; 7454; 5248 ER - TY - JOUR T1 - Teachers as Writers: Who Me? AN - 61921160; EJ793873 AB - In an earlier edition of this journal, Paul Swan (1997) published an article called "Writing for journals: An avenue for professional development". His article encourages teachers to share their experiences and ideas by becoming writers of APMC journal articles, and in doing so, engage in professional development. The set of guidelines Swan provided for developing an article for submission has inspired this new article. In this article, the author also urges primary school teachers in Australia to share their experiences and become contributors to this journal. JF - Australian Primary Mathematics Classroom AU - Way, Jenni Y1 - 2004 PY - 2004 DA - 2004 SP - 4 EP - 6 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 1 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Writing for Publication KW - Writing (Composition) KW - Foreign Countries KW - Faculty Publishing KW - Guidelines KW - Teachers KW - Elementary School Teachers KW - Faculty Development KW - Journal Articles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61921160?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 3365 10591 8267 3417 8016 4542 5703 4908 8917; 4566; 5602 8477; 4109 4335; 10591 8267 3417 8016 4542 5703 4908 8917; 3787 8258 5704 2787 10010; 11614 5752 6101; 11627 11614 5752 6101; 3799 ER - TY - JOUR T1 - Estimation with 2-Digit Addition and Multiplication AN - 61921119; EJ793884 AB - Estimation is an important skill for everyday living. Good estimators usually have a sound knowledge of basic facts, understand place value and use a variety of strategies to make their estimates. This paper describes an activity which is designed to provide students with opportunities to practice their rounding strategies with addition and multiplication. In particular, the activity shows that estimates fall within limits and that sometimes, an exaggerated estimate will not be useful. JF - Australian Primary Mathematics Classroom AU - Bobis, Janette Y1 - 2004 PY - 2004 DA - 2004 SP - 15 EP - 18 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 2 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Thinking Skills KW - Multiplication KW - Mathematics Instruction KW - Number Concepts KW - Mathematics KW - Arithmetic KW - Computation KW - Foreign Countries KW - Educational Games KW - Mathematics Activities KW - Learning Strategies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61921119?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7190 6396; 2003 6394; 6419 5242; 6410 5964; 6412 126; 5911 6582; 3206 4270 126; 4109 4335; 8179 3352 3368 3150 3085; 10852 1701 1 9690; 610 6410 5964; 6879 610 6410 5964 ER - TY - JOUR T1 - McDonald's vs Father Christmas AN - 61921071; EJ793890 AB - Mathematics in textbooks and indeed in conventional classrooms is often presented as exercises or worksheets in which the mathematics itself has been processed into a form that is easily digested. This McDonald's version of mathematics ensures that the mathematical skill or technique is laid bare and typically the sole focus of attention. In this paper the mathematical focus is directed number, though the reader will soon become aware that the children's activity spans a rich panoply of disciplines. By directed number, the authors refer to positive and negative numbers. In this context, McDonald's mathematics might take the form of an exercise in which the children are presented with a series of additions of one negative number to another. Here, the authors demonstrate the difference between providing pre-processed mathematics for students and rich contexts for exploring mathematical ideas. (Contains 2 figures and 1 footnote.) JF - Australian Primary Mathematics Classroom AU - Pratt, Dave AU - Simpson, Amanda Y1 - 2004 PY - 2004 DA - 2004 SP - 4 EP - 9 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 3 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Thinking Skills KW - Questioning Techniques KW - Mathematics Instruction KW - Maps KW - Computer Uses in Education KW - Computation KW - Foreign Countries KW - Textbooks KW - Mathematics Activities KW - Worksheets KW - Classroom Communication KW - Prior Learning KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61921071?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 10813 1114 8193 8477 5258 3224; 6419 5242; 10621 3227 6582; 8179 3352 3368 3150 3085; 4109 4335; 10852 1701 1 9690; 11592 8697; 6412 126; 2074 2073 10675; 8200 5882; 1600 1849; 2003 6394; 6315 11302; 8534 6582 ER - TY - JOUR T1 - Computation Choices Made by Children: What, Why and How AN - 61921019; EJ793896 AB - Mathematics curriculum documents highlight the need for students to be able to choose from a repertoire of computational tools and strategies, but little direction is given as to how children choose which form of computation to use in any given situation. In this article, the author reports on the classroom implications of research designed to determine the computation choices made by 10-12 year old students. He discusses which choices were made, why they were made and how successful students were in executing their choices. (Contains 2 tables.) JF - Australian Primary Mathematics Classroom AU - Swan, Paul Y1 - 2004 PY - 2004 DA - 2004 SP - 27 EP - 30 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 3 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Thinking Skills KW - Computation KW - Foreign Countries KW - Mental Computation KW - Mathematics Instruction KW - Mathematics Curriculum KW - Interviews KW - Feedback (Response) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61921019?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6416 2515; 4109 4335; 8179 3352 3368 3150 3085; 2003 6394; 10852 1701 1 9690; 6419 5242; 5472 3629 6582; 3924 5348 8768; 6529 2003 6394 1710 ER - TY - JOUR T1 - Assessing Numeracy in the Primary School AN - 61920372; EJ793951 AB - This article reports on the Australian Capital Territory (ACT) project, entitled "Assessing numeracy in primary schools" (ANIPS) aimed at improving student numeracy outcomes through the development of a whole-school approach that links a comprehensive assessment regime with numeracy teaching and learning. The project examined how the results from a variety of assessment tools could be used to improve student numeracy outcomes. Classroom assessment practices were identified that complement system and/or school assessment procedures. Teaching approaches that make effective use of assessment to support student learning, particularly for "at risk" students were highlighted. The project had a considerable effect in increasing the range of assessment approaches used by project teachers in their classrooms. JF - Australian Primary Mathematics Classroom Y1 - 2004 PY - 2004 DA - 2004 SP - 43 EP - 44 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Evaluation Methods KW - Elementary School Mathematics KW - Program Effectiveness KW - High Risk Students KW - Foreign Countries KW - Mathematics Instruction KW - Numeracy KW - Student Evaluation KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61920372?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7196; 8299; 10621 3227 6582; 10205 3626; 3360 6416 2515 3357; 6419 5242; 4109 4335; 3629 6582; 4723 ER - TY - JOUR T1 - Primary Numeracy: A Review of Australian Research AN - 61919899; EJ793920 AB - A major policy objective of the Australian Government is to provide all young people with strong foundations in numeracy. This article reports on a national project coordinated by Deakin University. The project, entitled "Primary numeracy: A mapping, review and analysis of Australian research in numeracy learning at the primary school level," was funded by the Department of Education, Science and Training, under the National Strand of the Numeracy Research and Development Initiative. The project involved analyzing the last decade of Australian research on primary school numeracy, and reviewing it within a broader international context. It involved making research summaries and findings accessible through the development of an indexed electronic database that holds the details of approximately 200 projects and 700 publications. Both this database and the final report were organized using the primary numeracy concept map. (Contains 1 figure.) JF - Australian Primary Mathematics Classroom AU - Groves, Susie AU - Mousley, Judy AU - Forgasz, Helen Y1 - 2004 PY - 2004 DA - 2004 SP - 10 EP - 13 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Databases KW - Information Technology KW - Foreign Countries KW - Concept Mapping KW - Numeracy KW - Politics of Education KW - Research and Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61919899?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 2083 6582; 8838; 7196; 2596 5162 2572; 7998 7997; 4109 4335; 8179 3352 3368 3150 3085; 5168 10669 ER - TY - JOUR T1 - Understanding Place-Value: A Case Study of the Base Ten Game AN - 61919851; EJ793952 AB - In this article, the author reports findings from a project designed to explore approaches for improving students' mathematical learning outcomes in relation to the base ten number system. The project explored the role of a commonly used teaching activity, referred to in the project as the "base ten game," in developing children's understanding of the number system. The game involves students using a place value board and concrete materials to develop an understanding of the structure of the number system and to learn to operate on numbers using this structure. This project revealed the necessity of explicitly developing links between the concrete materials, the learning activities, and the structure of the number system to support the development of relational understanding of place-value. (Contains 3 figures.) JF - Australian Primary Mathematics Classroom AU - Broadbent, Andrea Y1 - 2004 PY - 2004 DA - 2004 SP - 45 EP - 46 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Primary Education KW - Educational Strategies KW - Indigenous Populations KW - Rural Schools KW - Action Research KW - Urban Schools KW - Number Systems KW - Number Concepts KW - Outcomes of Education KW - Foreign Countries KW - Educational Games KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61919851?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7193 7195 10407; 7190 6396; 10621 3227 6582; 7454; 3264 3227 6582; 3206 4270 126; 8179 3352 3368 3150 3085; 4109 4335; 122 8836; 9061 9306 5241; 11182 9306 5241; 5046 8016 4542 ER - TY - JOUR T1 - Sitting at the Back: Noticing "Math Noticing" AN - 61919535; EJ793874 AB - Recently, the author has been fortunate to be a visitor in a number of classrooms in the United States, England and Europe. On one such visit to an Elementary School in Columbia, Missouri, the teachers accepted him into their normal classrooms for their normal lessons. He moved between three classes: Grade 1, Grade 2 and Grade 4. A snapshot account of what he saw and his reactions are presented. Here, the author highlights the significance of helping children make connections in mathematics via problem solving. He describes how teachers encourage children to think mathematically by "taking notice" of the mathematics they encounter. JF - Australian Primary Mathematics Classroom AU - Sparrow, Len Y1 - 2004 PY - 2004 DA - 2004 SP - 7 EP - 12 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 1 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Grade 1 KW - Grade 2 KW - Grade 4 KW - Elementary School Mathematics KW - Mathematical Logic KW - Mathematics Instruction KW - Mathematical Concepts KW - Learning Strategies KW - Problem Solving UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61919535?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4421 5264; 4419 5264; 4413 5264; 8233 1710; 6419 5242; 5911 6582; 6403; 3360 6416 2515 3357; 6396 ER - TY - JOUR T1 - Getting Integrated Real-World Mathematics Ideas Is as Simple as Reading the Morning Paper AN - 61919481; EJ793876 AB - There is great variety in the numerous mathematical lesson ideas that can arise from browsing through the newspaper. Since they depict recent, topical material that is constantly changing, newspapers provide an endless supply of new ideas with each new day. In this article, the author provides numerous suggestions as to how the newspaper can be used in mathematical lesson planning. JF - Australian Primary Mathematics Classroom AU - Miller, Debora Y1 - 2004 PY - 2004 DA - 2004 SP - 28 EP - 32 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 1 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Creative Teaching KW - Elementary School Mathematics KW - Newspapers KW - Foreign Countries KW - Mathematics Instruction KW - Lesson Plans KW - Planning KW - Relevance (Education) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61919481?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6419 5242; 7073 7068 6362; 8774; 5954; 7921; 4109 4335; 3360 6416 2515 3357; 2384 10621 3227 6582 ER - TY - JOUR T1 - The Role of Mathematical Fiction in the Learning of Mathematics in Primary School AN - 61916684; EJ793882 AB - This article classifies and describes a selection of mathematical fiction. It also provides some practical activities teachers or parents can use to help make the mathematics more explicit and engaging for their children. Not many people, apart from primary teachers, are aware of mathematical fiction or mathematical picture storybooks, although the study of such books is not a completely new phenomenon. The history of the mathematical storybook probably began as long ago as 1865 with "Alice's Adventures in Wonderland" by Lewis Carroll, a pseudonym of Charles Dodgson, mathematician, or earlier still with parts of Swift's "Gulliver's Travels" in 1726. (Contains 1 figure.) JF - Australian Primary Mathematics Classroom AU - Padula, Janice Y1 - 2004 PY - 2004 DA - 2004 SP - 8 EP - 14 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 2 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Elementary School Mathematics KW - Arithmetic KW - Mathematical Logic KW - Fiction KW - Integrated Curriculum KW - Picture Books KW - Mathematical Concepts KW - Childrens Literature KW - Mathematics Education KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61916684?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 1482 6120 4918 5964; 3946 8371 6120 4918 5964; 6417 3150; 3360 6416 2515 3357; 5299 5294 126 2515; 10621 3227 6582; 7898 1114 8193 8477; 610 6410 5964; 6396; 6403 ER - TY - JOUR T1 - Numbers + Magic = Answer. Students Explaining: Make the Most of Mental Computation AN - 61916639; EJ793892 AB - Facilitating mental computation discussion comes with its own set of challenges for researchers and teachers. It is important to be able to help capture the students' ideas, before they disappear and seem like little more than moments of magic! In enabling children to learn how numbers work, the current emphasis on mental computation is driven by the principles of constructive learning. It is here that questions of "how" and "why" become particularly important for both teachers and students. When students are working mentally, simple questions posed to an individual or a class of students, such as, "How did you work this out?" and, "Why does that work?" allow teachers to peer into the world of numbers and gain an understanding from the perspective of the students. It also encourages students to re-evaluate their own ideas when exposed to the thinking of their peers. Experiences that encourage discussion and learning are far removed from the emphasis on activities that focus on testing that have dominated mental computation in primary and secondary classrooms for so long. Many teachers rightly feel that testing activities of some sort still have a place in the classroom, for example, as a quick way of gauging what types of questions students are able to cope with. However, as the sole approach to teaching mental computation, they really are a thing of the past. In this article, the author provides questioning techniques to help teachers "capture" the mathematical ideas of children as they explain their mental computation strategies. JF - Australian Primary Mathematics Classroom AU - Caney, Annaliese Y1 - 2004 PY - 2004 DA - 2004 SP - 10 EP - 14 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 3 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Secondary Education KW - Questioning Techniques KW - Mathematics Instruction KW - Perspective Taking KW - Testing KW - Foreign Countries KW - Mental Computation KW - Teachers KW - Constructivism (Learning) KW - Learning Strategies KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61916639?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 8534 6582; 10783 6446 6582; 6529 2003 6394 1710; 10591 8267 3417 8016 4542 5703 4908 8917; 10621 3227 6582; 4109 4335; 6419 5242; 2158 5913 10830; 7782; 5911 6582; 8179 3352 3368 3150 3085; 9409 3368 3150 ER - TY - JOUR T1 - Profiling High Numeracy Achievement AN - 61915093; EJ793949 AB - Profiling high numeracy achievement is the South Australian Department of Education and Children's Services component of the Australian Government funded Strategic Numeracy Research and Development Initiative. This article presents the Profiling High Numeracy Achievement Project Team report on the South Australian Department of Education and Children's Services numeracy project. The South Australian project was managed collaboratively by the South Australian Primary Principals' Association and the Learning Outcomes and Curriculum Group. The Flinders Institute for the Study of Teaching conducted the research component of the project. The project investigated factors enabling students to become high numeracy performers. It aimed to identify whole-school structures and effective teaching practices that support improved numeracy outcomes, and to develop a coordinated and strategic plan for numeracy improvement at the system, school, and classroom level. Key findings from this research indicate that more substantial and enduring changes to numeracy practices require a whole-school response to ensure an integrated and coherent approach to school planning, professional development, and resource acquisition. (Contains 1 figure.) JF - Australian Primary Mathematics Classroom Y1 - 2004 PY - 2004 DA - 2004 SP - 35 EP - 38 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Practitioners KW - Elementary Education KW - Elementary School Mathematics KW - High Achievement KW - Foreign Countries KW - Mathematics Instruction KW - Educational Change KW - Numeracy KW - Mathematics Achievement KW - Teacher Effectiveness KW - Strategic Planning KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61915093?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 10141 7921; 10514 10486 909; 7196; 10621 3227 6582; 4109 4335; 6419 5242; 6411 96; 4718 96; 3360 6416 2515 3357; 3176 1387 ER - TY - JOUR T1 - Social Interaction: A Vehicle for Building Meaning AN - 61915029; EJ793950 AB - Two project researchers worked collaboratively with 10 Year 3-5 classroom teachers across nine schools in metropolitan and country regions of South Australia to answer the question: "What teaching strategies support all students to improve their numeracy outcome through the construction of meaningful understanding?". The research identified that there is no single aspect of teaching or no single environment feature that will, by itself, result in improved outcomes for all students. Rather, supporting students to think and work mathematically requires a combination of pre-arranged conditions and responsive teaching strategies. This paper concentrates on just one of the findings: namely that learning is confirmed as not solely an active personal construction of knowledge, but is also influenced by the social environment in which it takes place. Interactions between teacher and student/s, and amongst students themselves, encouraged students to think, verbalize and analyze their own views of mathematical and numeracy concepts. JF - Australian Primary Mathematics Classroom AU - O'Toole, Trish AU - Plummer, Christelle Y1 - 2004 PY - 2004 DA - 2004 SP - 39 EP - 42 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Primary Education KW - Small Group Instruction KW - Thinking Skills KW - Educational Strategies KW - Interaction KW - Questioning Techniques KW - Classroom Environment KW - Mathematics Instruction KW - Case Studies KW - Numeracy KW - Feedback (Response) KW - Scaffolding (Teaching Technique) KW - Foreign Countries KW - Interpersonal Relationship KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61915029?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7196; 5449 8768; 4109 4335; 10621 3227 6582; 3264 3227 6582; 10852 1701 1 9690; 6419 5242; 3924 5348 8768; 1326 3629 6582 8836; 1604 3190 3518; 5348 8768; 9716 4520 5242; 9121 10621 3227 6582; 8534 6582 ER - TY - JOUR T1 - Poster Power AN - 61912759; EJ793897 AB - There are many ways for children to engage in learning and experiencing mathematics and posters are one of them. From the author's observation of many classrooms the most common mathematical poster to be seen was the faithful multiplication times-tables. The purpose of this article is to encourage the use of effective posters and other visual aides in the classroom to support learning and show some of the fun, exciting depth of mathematics that occurs in the real world. The use of posters to display and challenge appears to be an untapped resource. This area has great potential to engage children. Considering the percentages of learning occurring through each of the senses supports the old saying "a picture is worth a thousand words". JF - Australian Primary Mathematics Classroom AU - Bayley, Dawn Y1 - 2004 PY - 2004 DA - 2004 SP - 31 EP - 32 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 3 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Sensory Aids KW - Visual Learning KW - Foreign Countries KW - Classroom Environment KW - Visual Aids KW - Learning Activities KW - Children KW - Mathematics Education KW - Teaching Methods KW - Mathematics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61912759?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 5883 126; 4109 4335; 1474 316 8016 4542; 6417 3150; 6410 5964; 11302; 11310 5882; 1604 3190 3518; 9527 683 10669; 10621 3227 6582 ER - TY - JOUR T1 - Developing Computation AN - 61911662; EJ793953 AB - In this article, the author presents the results of a state project that focused on the effect of developing informal written computation processes through Years 2-4. The "developing computation" project was conducted in Tasmania over the two years 2002-2003 and involved nine schools: five government schools, two Catholic schools, and two independent schools. All Years 2, 3 and 4 teachers (a total of 37 teachers) in the project schools were involved. All teachers in the project agreed that the concentration on mental computation had greatly increased children's competence and confidence in handling numbers and in understanding place value. Most schools saw prep or kindergarten as the best time to start this approach for the majority of children. Whereas most teachers previously would have advocated the introduction of standard written algorithms from Years 1 or 2, they now suggested Year 4 as more appropriate. All teachers agreed on the benefits of developing informal written methods as a bridge between mental and formal written methods. (Contains 1 table and 4 figures.) JF - Australian Primary Mathematics Classroom AU - McIntosh, Alistair Y1 - 2004 PY - 2004 DA - 2004 SP - 47 EP - 49 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Elementary School Mathematics KW - Catholic Schools KW - Public Schools KW - Foreign Countries KW - Mathematics Instruction KW - Mental Computation KW - Mathematics Skills KW - Private Schools KW - Number Concepts KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61911662?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 1343 7594 8216 9306 5241; 6529 2003 6394 1710; 7190 6396; 10621 3227 6582; 4109 4335; 8467 9306 5241; 8216 9306 5241; 6421 9690 1; 6419 5242; 3360 6416 2515 3357 ER - TY - JOUR T1 - Teachers Enhancing Numeracy AN - 61911622; EJ793955 AB - In this article, the author presents findings of a project that focused on identifying elements in the learning environment that promote numeracy outcomes. The project--"Numeracy Research and Development Initiative"--was undertaken in eight schools across a range of settings within the three schooling systems in Queensland and was coordinated by Education Queensland. A research team of 10 primary mathematics educators formed from four Queensland universities collaborated with teachers and administrators in the project schools. The teacher-academic collaborations impacted positively on almost all the project teachers in terms of teacher mathematics knowledge, mathematics teaching knowledge, and classroom engagement (especially confidence). These factors, in turn, enhanced teachers' classroom practices and student numeracy outcomes. The collaborations also assisted teachers in planning connected units of work based on students' prior knowledge, in selecting and using appropriate resources, in organising and managing activity and discussion, and in reviewing their ideas about appropriate classroom enquiry. Teachers' beliefs about mathematics and its teaching, learning, and assessment were challenged and changed and this, in turn, was reflected in improved classroom practices that enhanced active learning, classroom enquiry, and students' numeracy outcomes. JF - Australian Primary Mathematics Classroom AU - Baturo, Annette Y1 - 2004 PY - 2004 DA - 2004 SP - 54 EP - 56 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Elementary School Mathematics KW - Teacher Collaboration KW - Mathematics Instruction KW - Numeracy KW - Teacher Attitudes KW - College School Cooperation KW - Elementary School Teachers KW - Mathematics Skills KW - Mathematics Education KW - Teacher Effectiveness KW - Classroom Techniques KW - Inquiry KW - Foreign Countries KW - Planning KW - Knowledge Base for Teaching KW - Active Learning KW - Teaching Methods KW - Prior Learning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61911622?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4109 4335; 3360 6416 2515 3357; 3365 10591 8267 3417 8016 4542 5703 4908 8917; 1798 3180 2221 909 5222; 10494 3180 2221 909 10486; 6419 5242; 5674; 1619 3227 6582; 10514 10486 909; 7921; 8200 5882; 5197 6582; 10621 3227 6582; 6417 3150; 7196; 10482 730; 124 5882; 6421 9690 1 ER - TY - JOUR T1 - The Development of Counting Cards: A New Maths Aid for Teaching Place Value, Addition and Subtraction up to 1 Million AN - 61910779; EJ793887 AB - In this article, the author presents a new maths aid for teaching place value, addition and subtraction up to 1 million. The need for a resource to help his wife understand place value motivated the author to create "Counting Cards". Here, he shares his invention, in the hope that it will help others. (Contains 4 figures.) JF - Australian Primary Mathematics Classroom AU - Taylor, Christian Y1 - 2004 PY - 2004 DA - 2004 SP - 25 EP - 27 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 2 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Adult Education KW - Higher Education KW - Primary Education KW - Intellectual Property KW - Subtraction KW - Mathematics Instruction KW - Dyslexia KW - Manipulative Materials KW - Mathematics Education KW - Number Concepts KW - Teaching Methods KW - Mathematics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61910779?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7190 6396; 10309 610 6410 5964; 6410 5964; 10621 3227 6582; 6419 5242; 6296 5258 3224; 3071 5770 2877; 8179 3352 3368 3150 3085; 4744 8046 3150; 5331 7487; 6417 3150 ER - TY - JOUR T1 - The Numeracy Research and Development Initiative Projects AN - 61909548; EJ793908 AB - In 2001, with funding of $7 million, the Australian Government implemented the "Numeracy Research and Development Initiative"--one of several initiatives introduced by the Australian Government to support literacy and numeracy improvement. Other initiatives included the "National Indigenous English Literacy and Numeracy Strategy," and the "Quality Teacher Program." The "Numeracy Research and Development Initiative" comprised two complementary strands: a national project strand and a strategic States and Territories projects strand. The purpose of these projects was to investigate a broad range of teaching and learning strategies that lead to improved numeracy outcomes. This article highlights the findings of the "Numeracy Research and Development Initiative" projects. The initiative has resulted in a deeper understanding of key issues surrounding numeracy education and has also opened up new opportunities for collaboration between universities and education sector authorities. The success of the numeracy projects has demonstrated the potential for research studies where teachers can participate as partners in research while engaging in their own professional development. A key outcome for the teachers involved in the projects has been the growth in their mathematical pedagogical knowledge and also in their own deeper understanding of the mathematical concepts they were teaching. These findings can be seen to have implications for numeracy teaching and learning at all levels of organisation, from government education policies to school administration and classroom practice. JF - Australian Primary Mathematics Classroom AU - Vincent, Jill Y1 - 2004 PY - 2004 DA - 2004 SP - 4 EP - 9 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - England KW - United States KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Government School Relationship KW - Numeracy KW - Teacher Education KW - Preservice Teacher Education KW - Research and Development KW - Mathematics Education KW - Partnerships in Education KW - Scaffolding (Teaching Technique) KW - Administration KW - Educational Change KW - Mathematical Concepts KW - Mathematics Teachers KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61909548?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7196; 8838; 3176 1387; 10621 3227 6582; 8144 10507 8260 3150; 10507 8260 3150; 7624 3180 2221 909; 8179 3352 3368 3150 3085; 6422 10591 8267 3417 8016 4542 5703 4908 8917; 6417 3150; 6396; 9121 10621 3227 6582; 4409 8768; 153 4398 ER - TY - JOUR T1 - Integrating Technology in the Middle School: Years 5-9 AN - 61907450; EJ793893 AB - In the past, graphic calculators have been sophisticated and exciting tools for higher mathematics, but few would have considered using them more than occasionally with younger students. All this has now changed with the growing range of software Apps now available for Texas Instruments TI-83 Plus calculators. These Apps are more like computer software than calculator programs and, in many ways, make the device more like a laptop than a calculator, especially when combined with the new keyboard, which supports the free "Microsoft Word"-compatible word processor, along with the spreadsheet, dynamic geometry and much more. In this article, the author presents a number of lesson outlines which he has used with upper primary through to secondary students in the past twelve months. The lessons described here explore applications to space, data and number. JF - Australian Primary Mathematics Classroom AU - Arnold, Stephen Y1 - 2004 PY - 2004 DA - 2004 SP - 15 EP - 19 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 3 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Middle Schools KW - Primary Education KW - Geometric Concepts KW - Mathematics Instruction KW - Elementary Secondary Education KW - Computer Software KW - Word Processing KW - Mathematics KW - Foreign Countries KW - Technology Integration KW - Mathematics Activities KW - Calculators KW - Educational Technology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61907450?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 2059; 3268 10669; 11543 5150 5159 9556; 1239 3553; 8179 3352 3368 3150 3085; 3368 3150; 6419 5242; 6410 5964; 4109 4335; 4339 6396; 6412 126; 10671 ER - TY - JOUR T1 - Teaching Children to Organise and Represent Large Data Sets in a Histogram AN - 61907152; EJ793875 AB - Although some bright students in primary school are able to organise numerical data into classes, most attend to the characteristics of individuals rather than the group, and "see the trees rather than the forest". How can teachers in upper primary and early high school teach students to organise large sets of data with widely varying values into groups, and to represent the resulting grouped data appropriately in a histogram? How can they choose data sets that allow integration of different topics in the mathematics curriculum? What involvement can students have in the data collection? In a "teaching experiment" with two year 7 classes in two different Queensland schools over a three-week period, the authors report on their teaching investigation in which students explore the organisation and grouping of data. They highlight the type of thinking needed to represent grouped data in graphs. (Contains 3 figures.) JF - Australian Primary Mathematics Classroom AU - Nisbet, Steven AU - Putt, Ian Y1 - 2004 PY - 2004 DA - 2004 SP - 13 EP - 17 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 1 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Grade 7 KW - Elementary School Mathematics KW - Elementary School Students KW - Foreign Countries KW - Mathematics Instruction KW - Mathematical Concepts KW - Data Analysis KW - Graphs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61907152?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6419 5242; 3360 6416 2515 3357; 4424 5264; 3363 10278 8016 4542; 4485 11302; 6396; 2574 3629 6582; 4109 4335 ER - TY - JOUR T1 - Cut Two Triangles AN - 61907101; EJ793894 AB - Sometimes simple ideas are more productive than complex and over-prepared lessons; perhaps because of the flexibility afforded both teachers and students. This article provides a description of the basic activity and the potential mathematics associated with it. It also gives examples of how the basic activity could be implemented with students of various stages of development, ranging from about 4 years to 12 years of age. JF - Australian Primary Mathematics Classroom AU - Way, Jenni Y1 - 2004 PY - 2004 DA - 2004 SP - 20 EP - 21 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 2 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Primary Education KW - Foreign Countries KW - Mathematics Instruction KW - Geometric Concepts KW - Mathematics Activities KW - Developmental Stages KW - Child Development KW - Mathematics Education KW - Teaching Methods KW - Mathematics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61907101?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4339 6396; 2798; 6419 5242; 6410 5964; 10621 3227 6582; 6412 126; 4109 4335; 8179 3352 3368 3150 3085; 6417 3150; 1443 5053 2787 ER - TY - JOUR T1 - Mystery and Movement: Doing More with Dominoes AN - 61906173; EJ793872 AB - In previous articles, the author has discussed dominoes, the real game with scoring, and other good games and activities using dominoes. But dominoes, as materials for game-playing, and as a topic for mathematics learning experiences, as suggested by Swan (2001) and Brandreth (1975), have many other possibilities. In this article, the author explains how to turn an ordinary set of dominoes into games of mystery, movement and strategy. JF - Australian Primary Mathematics Classroom AU - Gough, John Y1 - 2004 PY - 2004 DA - 2004 SP - 18 EP - 21 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 1 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Elementary School Mathematics KW - Learning Activities KW - Games KW - Manipulative Materials KW - Mathematics Education KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61906173?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6417 3150; 10621 3227 6582; 3360 6416 2515 3357; 4270 126; 6296 5258 3224; 5883 126 ER - TY - JOUR T1 - Numeracy in the Early Years: Project Good Start AN - 61906121; EJ793943 AB - "Numeracy in the early years: Project good start" was a national project that commenced in 2001, and will conclude this year. The key objective of the project is to improve children's early numeracy outcomes by investigating the practices and learning experiences that support the numeracy development of a sample of children in the year before school and in their first year of formal schooling. Case studies of some of these children were also prepared and analysed. Children's before-school experiences (including at home, and in preschool and childcare settings) and first year of school experiences were examined, with a particular focus on factors affecting early numeracy development. The project investigated the effects of children's backgrounds (for example, geographically isolated, rural, low socioeconomic urban areas, and areas with high indigenous populations); the different numeracy programs that these children encounter; the beliefs of parents and practitioners regarding numeracy development and learning; effective teaching strategies in numeracy and the identification of "at risk" children in numeracy. (Contains 2 figures.) JF - Australian Primary Mathematics Classroom AU - Thomson, Sue Y1 - 2004 PY - 2004 DA - 2004 SP - 14 EP - 17 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Early Childhood Education KW - Primary Education KW - Program Effectiveness KW - High Risk Students KW - Indigenous Populations KW - Play KW - Gender Differences KW - Case Studies KW - Numeracy KW - Identification KW - Rural Areas KW - Teacher Effectiveness KW - Foreign Countries KW - Urban Areas KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61906121?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 10514 10486 909; 5046 8016 4542; 7196; 11162 4335; 10621 3227 6582; 8179 3352 3368 3150 3085; 4109 4335; 3085 3150; 9046 4335; 4954; 4723; 1326 3629 6582 8836; 4290; 7940 126; 8299 ER - TY - JOUR T1 - All at Sixes... AN - 61906114; EJ793880 AB - In this article, the authors would like to look at a range of solutions submitted by Year 4-5 teams in the 2003 "Naturally Mathematical Challenge" to a question that involves no more than the numbers 1 to 6 and possible arrangements of them. In the context of other competition questions and in their elaboration of mathematical process, they have described the way in which Polya's four step heuristic for problem solving, now popularly known as the "See, Plan, Do, Check model", can be used by students not only to guide their initial thinking, but also as a framework for reporting on their method of solution. This article shows how the model can be used effectively by students in the middle primary years; but not all teams adhere to the model, and the authors also give examples where a "guess and check" approach is used, and they point out the severe limitations of this approach. In contrast, they also show how a systematic listing of possibilities can lead to a very complete solution. JF - Australian Primary Mathematics Classroom AU - Baker, John AU - Baker, Ann Y1 - 2004 PY - 2004 DA - 2004 SP - 4 EP - 7 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 2 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Grade 4 KW - Grade 5 KW - Elementary School Mathematics KW - Heuristics KW - Mathematics Instruction KW - Manipulative Materials KW - Number Concepts KW - Models KW - Problem Solving KW - Mathematical Logic KW - Competition KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61906114?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 3360 6416 2515 3357; 4421 5264; 4422 5264; 7190 6396; 1974 909; 6403; 4713 6582; 6419 5242; 8233 1710; 10621 3227 6582; 6752 9651 6582; 6296 5258 3224 ER - TY - JOUR T1 - Researching Numeracy Teaching Approaches in Primary Schools AN - 61906081; EJ793947 AB - The "Researching numeracy" project aimed to identify effective classroom teaching approaches in mathematics for students in the early years (Prep-Year 4) and the middle years (Years 5 and 6) in a range of Victorian schools. The action research component of the project involved the research team working with teachers from sixteen research schools as they enacted their action plans and helped identify and describe a range of numeracy teaching approaches. To evaluate the effectiveness of the proposed numeracy teaching approaches, sample based, student interview data were collected at the beginning and end of the project from both the research schools and a matched set of reference schools. A major outcome of the project is the identification, description and elaboration of twelve scaffolding practices that contribute to improved student learning outcomes in a range of Victorian primary school settings, including a special school. This article provides a brief description of each scaffolding practices. JF - Australian Primary Mathematics Classroom Y1 - 2004 PY - 2004 DA - 2004 SP - 27 EP - 29 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Elementary School Mathematics KW - Instructional Effectiveness KW - Elementary School Students KW - Foreign Countries KW - Scaffolding (Teaching Technique) KW - Action Research KW - Numeracy KW - Interviews KW - Special Schools KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61906081?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 9939 9306 5241; 122 8836; 7196; 10621 3227 6582; 3360 6416 2515 3357; 3363 10278 8016 4542; 5248; 5472 3629 6582; 9121 10621 3227 6582; 4109 4335 ER - TY - JOUR T1 - An Investigation into Student Numeracy across the Curriculum AN - 61904992; EJ793948 AB - If numeracy is about improving students' use of mathematics in life, then numeracy education cannot be restricted to the mathematics classroom: students need to apply the mathematics they learn across the curriculum and beyond the classroom. Hence, there is more that educators need to discover about how well students can use mathematics in settings other than schools mathematics classes, and about the extent and nature of the relationship between students' mathematics knowledge and their capacity to use mathematics in context. In this article, the Numeracy across the Curriculum Project Team presents findings from a Western Australian project coordinated by a team from Murdoch, Curtin and Edith Cowan Universities. This project has taken the view that numeracy, at the very least, is the ability and willingness to use mathematics to meet the demands of life at home, in education, in paid work, and for participation in the community and civic life. This article also presents teaching strategies for numeracy. (Contains 2 figures.) JF - Australian Primary Mathematics Classroom Y1 - 2004 PY - 2004 DA - 2004 SP - 30 EP - 34 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Primary Education KW - Qualitative Research KW - Educational Strategies KW - Catholic Schools KW - Mathematics Instruction KW - Numeracy KW - Critical Thinking KW - Mathematics Education KW - Foreign Countries KW - Mathematics Teachers KW - Private Schools KW - State Schools KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61904992?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 7196; 6419 5242; 10621 3227 6582; 6417 3150; 4109 4335; 8179 3352 3368 3150 3085; 6422 10591 8267 3417 8016 4542 5703 4908 8917; 3264 3227 6582; 8517 8836; 1343 7594 8216 9306 5241; 8216 9306 5241; 10072 9306 5241; 2432 1710 ER - TY - JOUR T1 - Numeracy: Families Working It out Together--The Opportunities Are Everywhere AN - 61904377; EJ793945 AB - There is ample evidence that positive involvement of families in children's learning can be a major contribution. Where to start is often a challenge, however, especially in the numeracy area. As part of the Australian Government's "Numeracy Research and Development Initiative" a team led by Beth Powell in Western Australia has developed a poster and three brochures aimed at promoting the importance of numeracy to parents. The brochures also provide some welcome starting points to help families be part of their child's numeracy development. There are brochures for different age groups: the early years, the middle, and later years of primary school. They can be used in a variety of ways by teachers and schools, for example in family mathematics programs. The team also produced a fridge list of examples for each age group. These are designed to be simple reminders that can be stuck on one of the most used appliances in the home. The samples shown in this article give some idea of what the materials are like--they are also able to be printed in full colour. Sample copies have been distributed to every primary school in Australia. JF - Australian Primary Mathematics Classroom AU - Morony, Will Y1 - 2004 PY - 2004 DA - 2004 SP - 21 EP - 23 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Parents KW - Teachers KW - Primary Education KW - Family Involvement KW - Age KW - Foreign Countries KW - Visual Aids KW - Numeracy KW - Mathematics Activities KW - Calculators KW - Research and Development KW - Publications KW - Mathematics Education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61904377?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 8838; 311 5051; 7196; 4109 4335; 3836 7615 909; 11302; 8477; 8179 3352 3368 3150 3085; 6417 3150; 1239 3553; 6412 126 ER - TY - JOUR T1 - What's Making the Difference in Achieving Outstanding Primary School Learning Outcomes in Numeracy? AN - 61904318; EJ793946 AB - In this article, the author presents findings from a large NSW project designed to explore educational practices that "make a difference" in numeracy outcomes. The project was coordinated by the NSW Department of Education and Training, the Catholic Education Commission, the Association of Independent Schools, and research teams from the University of New England, Southern Cross University, University of Technology, Sydney, University of Western Sydney, and the University of Wollongong. During 2001 and 2002, case studies were conducted in forty-five government and non-government primary schools across NSW where "outstanding" numeracy outcomes were being achieved at Years 3 and 5, and between Years 3 and 5, as indicated by Basic Skills Test data. These schools represented students from diverse socio-economic, language backgrounds other than English (LBOTE), Aboriginal and Torres Strait Islander (ATSI) and geographic communities (including isolated, metropolitan, rural, small and large schools). The sample comprised 70% Government, 20% Catholic and 10% Independent primary schools. Five university research teams were contracted to conduct the case studies in order to identify those factors that influenced student learning. The case studies included: interviews with teachers, parents, students, and community members; observations of numerous classroom mathematics/numeracy lessons; and the examination of many school documents. The main factors which were found to be "making the difference", as well as the strategies that enabled them to occur are grouped below according to three contexts: "within the classroom", "throughout the school" and "beyond the school". These factors and strategies seemed to fit together to provide a coherent guideline and philosophy for successful numeracy teaching. JF - Australian Primary Mathematics Classroom AU - Busatto, Susan Y1 - 2004 PY - 2004 DA - 2004 SP - 24 EP - 26 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Elementary Education KW - Elementary School Mathematics KW - Catholic Schools KW - Elementary School Students KW - Mathematics Instruction KW - Case Studies KW - Numeracy KW - Mathematics Achievement KW - Observation KW - Mathematics Skills KW - Foreign Countries KW - Public Schools KW - Educational Practices KW - Interviews KW - Private Schools UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61904318?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 1343 7594 8216 9306 5241; 8216 9306 5241; 8467 9306 5241; 3360 6416 2515 3357; 6419 5242; 6411 96; 6421 9690 1; 3363 10278 8016 4542; 7196; 3242; 4109 4335; 1326 3629 6582 8836; 5472 3629 6582; 7234 ER - TY - JOUR T1 - I Can Do Maths Too--Count Me in! AN - 61902166; EJ793877 AB - Since the early 1980s, it has become increasingly common for children with special needs to be included in regular classrooms. In this article, the author addresses issues surrounding the inclusion of students with special needs into the regular classroom. She discusses potential sources of difficulty with mathematics and suggests strategies to help teachers effectively manage the learning of special needs students in their classes. JF - Australian Primary Mathematics Classroom AU - Faragher, Rhonda Y1 - 2004 PY - 2004 DA - 2004 SP - 23 EP - 27 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 1 SN - 1326-0286, 1326-0286 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Inclusive Schools KW - Mathematics Instruction KW - Special Needs Students KW - Mainstreaming KW - Down Syndrome KW - Classroom Techniques KW - Regular and Special Education Relationship KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61902166?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 5018; 8754 8768; 1619 3227 6582; 10621 3227 6582; 9934 10278 8016 4542; 6250 7912; 6419 5242; 2995 2118 2877 6540 ER - TY - JOUR T1 - Home, School and Community Partnerships to Support Children's Numeracy AN - 61901124; EJ793944 AB - In this article, the author presents findings from a national project coordinated by the University of Queensland. The project was designed to explore the links between home, school, and community that supported children's numeracy development. Two of the aims of this project were to: (a) critically review recent Australian and international research in this area, with a particular emphasis on the extent to which the needs of educationally disadvantaged students are addressed in current practice and research; and (b) identify, describe, and analyse the current range of home, school, and community partnership practices in Australia that support children's numeracy learning in the one to two years prior to school and in the primary years of schooling. JF - Australian Primary Mathematics Classroom AU - Goos, Merrilyn Y1 - 2004 PY - 2004 DA - 2004 SP - 18 EP - 20 PB - Australian Association of Mathematics Teachers (AAMT). GPO Box 1729, Adelaide 5001, South Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: office@aamt.edu.au; Web site: http://www.aamt.edu.au VL - 9 IS - 4 SN - 1326-0286, 1326-0286 KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Community KW - Parents KW - Teachers KW - Early Childhood Education KW - Primary Education KW - School Community Relationship KW - Indigenous Populations KW - Principals KW - Case Studies KW - Numeracy KW - National Programs KW - Mathematics Education KW - Partnerships in Education KW - Foreign Countries KW - Parent Participation KW - Educationally Disadvantaged KW - Interviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61901124?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 3276 2883 8016 4542; 7196; 4109 4335; 8179 3352 3368 3150 3085; 3085 3150; 6950 8331; 5472 3629 6582; 1326 3629 6582 8836; 8190 9247 3417 8016 4542 5703 4908 8917 183; 5046 8016 4542; 7624 3180 2221 909; 7550 7615 909; 9190 8768; 6417 3150 ER - TY - JOUR T1 - Study Groups as a Tool for Enhancing Preservice Students' Content Knowledge AN - 61848431; EJ852382 AB - This paper explores the use of study groups in a preservice primary mathematics education subject where discipline knowledge (mathematics) is integrated with pedagogical knowledge (mathematics education). In order to address the well-recognized fear and competency levels of preservice teachers in the study of mathematics, study groups were explored as a medium for enhancing learning--both cognitive and affective. Overall, those students who used study groups reported that they were very effective forums for enhancing cognitive and affective learning outcomes in mathematics. JF - Mathematics Teacher Education and Development AU - Zevenbergen, Robyn Y1 - 2004 PY - 2004 DA - 2004 SP - 3 EP - 20 PB - Mathematics Education Research Group of Australasia. GPO Box 2747, Adelaide SA 5001, Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: mted@merga.net.au; Web site: http://www.merga.net.au/ VL - 6 SN - 1442-3901, 1442-3901 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Higher Education KW - Elementary School Mathematics KW - Study KW - Group Activities KW - Pedagogical Content Knowledge KW - Mathematics Instruction KW - Preservice Teachers KW - Mathematics Education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61848431?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 10281 5883 126; 4509 126; 8145 1806 10278 8016 4542; 3360 6416 2515 3357; 6417 3150; 6419 5242; 7657 5674 ER - TY - JOUR T1 - Professional Development: Mathematical Content versus Pedagogy AN - 61846812; EJ852385 AB - Recent teacher professional development in California tends to focus on increasing teachers' mathematical knowledge. In Australia, pedagogically focused programs are preferred. The two approaches are contrasted by comparing a Californian professional development model based on improving mathematical knowledge in number and algebra with a New South Wales school-based model involving the teaching of angle concepts. In both approaches, strengths and weaknesses are identified in terms of appropriate mathematical content, research-based pedagogy, and accreditation. Examples of courses incorporating all these components are given, and difficulties associated with implementing such courses are identified. Two important criteria for success, perceived relevance and teacher enthusiasm, are seen to be dependent on cultural factors in the education systems involved. (Contains 2 figures.) JF - Mathematics Teacher Education and Development AU - White, Paul AU - Branca, Nicholas AU - Mitchelmore, Michael AU - Maxon, Michael Y1 - 2004 PY - 2004 DA - 2004 SP - 41 EP - 52 PB - Mathematics Education Research Group of Australasia. GPO Box 2747, Adelaide SA 5001, Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: mted@merga.net.au; Web site: http://www.merga.net.au/ VL - 6 SN - 1442-3901, 1442-3901 KW - California KW - Australia KW - ERIC, Current Index to Journals in Education (CIJE) KW - Mathematics Instruction KW - Professional Development KW - Mathematics Education KW - Models KW - Comparative Analysis KW - Pedagogical Content Knowledge KW - Foreign Countries KW - Cultural Influences KW - Accreditation (Institutions) KW - Teacher Motivation KW - Relevance (Education) KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61846812?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6417 3150; 4109 4335; 2484 5127; 8258 5704 2787; 1955 3629 6582; 7657 5674; 10621 3227 6582; 6419 5242; 10541 6827; 8774; 90 1377; 6752 9651 6582 ER - TY - JOUR T1 - Design Principles for Teacher Investigations of Student Work AN - 61839384; EJ852386 AB - This article describes a specific approach to a teacher investigation of students' written work. The aim of the investigation was for in-service middle school teachers to externalize their thinking about their students' mathematical thinking and to then reflect upon these externalizations and make refinements accordingly. This aim mirrors the purposes of student-level mathematical activities entitled model-eliciting activities. Therefore, the teacher investigation was patterned after the design principles for student-level model-eliciting activities. These design principles and how the teacher investigation was modeled after these principles are described. In addition, the teachers' externalizations, reflections upon, and revisions to their thinking about their students' thinking are explained. The article concludes with general design principles that other teacher educators can use in designing their respective professional development contexts. (Contains 3 footnotes, 1 table and 1 figure.) JF - Mathematics Teacher Education and Development AU - Chamberlin, Michelle Y1 - 2004 PY - 2004 DA - 2004 SP - 52 EP - 65 PB - Mathematics Education Research Group of Australasia. GPO Box 2747, Adelaide SA 5001, Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: mted@merga.net.au; Web site: http://www.merga.net.au/ VL - 6 SN - 1442-3901, 1442-3901 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Middle Schools KW - Mathematics Instruction KW - Inservice Teacher Education KW - Reflective Teaching KW - Professional Development KW - Investigations KW - Instructional Design KW - Middle School Teachers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61839384?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6419 5242; 5246 2768; 5208 5205 3150 10507 8260; 6645 10591 8267 3417 8016 4542 5703 4908 8917; 8725; 5500 8836; 8258 5704 2787 ER - TY - JOUR T1 - Problem Solving and the Initial Practical and Theoretical Education of Teachers in Spain AN - 61837170; EJ852384 AB - Several developments during the last decades have provoked spectacular changes in both Mathematics Teaching and the Education of Mathematics Teachers. From this perspective of renovation, we wish to define a new context in mathematics teacher education in which we consider that "pedagogical content knowledge" (Shulman, 1993, Mellado, 1998; Blanco & Otano, 1999) has to be the knowledge base for the education of the future teachers. In the present work, using problem solving as reference, we explain our program and different types of activities which help to create learning environments referred to "learning to teach mathematics". These activities allow the prospective teachers to build up their own pedagogical content knowledge. (Contains 2 figures.) JF - Mathematics Teacher Education and Development AU - Blanco, Lorenzo Y1 - 2004 PY - 2004 DA - 2004 SP - 31 EP - 42 PB - Mathematics Education Research Group of Australasia. GPO Box 2747, Adelaide SA 5001, Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: mted@merga.net.au; Web site: http://www.merga.net.au/ VL - 6 SN - 1442-3901, 1442-3901 KW - Spain KW - ERIC, Current Index to Journals in Education (CIJE) KW - Higher Education KW - Pedagogical Content Knowledge KW - Foreign Countries KW - Mathematics Teachers KW - Problem Solving KW - Teacher Education Programs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61837170?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4109 4335; 6422 10591 8267 3417 8016 4542 5703 4908 8917; 10511 8331; 7657 5674; 8233 1710 ER - TY - JOUR T1 - Coaching Teachers to Implement Mathematics Reform Recommendations AN - 61836173; EJ852387 AB - Historically, teachers implemented mathematics reform recommendations by infusing new activities into the curriculum. However, mathematics instruction continues to be teacher centred, challenging professional developers to find new ways to encourage teachers' growth. This study used activity-reflective cycles (Tzur & Simon, 1999) to examine different coaching approaches to support teachers' use of rich mathematical tasks and questions to promote students' mathematical thinking. We suggest a new coaching approach characterised as "evoking teachers' pedagogical curiosity" to advance teachers' professional growth. (Contains 2 tables and 1 figure.) JF - Mathematics Teacher Education and Development AU - Olson, Jo AU - Barrett, Jeffrey Y1 - 2004 PY - 2004 DA - 2004 SP - 63 EP - 80 PB - Mathematics Education Research Group of Australasia. GPO Box 2747, Adelaide SA 5001, Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: mted@merga.net.au; Web site: http://www.merga.net.au/ VL - 6 SN - 1442-3901, 1442-3901 KW - ERIC, Current Index to Journals in Education (CIJE) KW - Teachers KW - Elementary Education KW - Elementary School Mathematics KW - Coaching (Performance) KW - Mathematics Instruction KW - Reflective Teaching KW - Professional Development KW - Mathematics Education KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61836173?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 6417 3150; 6419 5242; 10621 3227 6582; 1684 6582; 8725; 8258 5704 2787; 3360 6416 2515 3357 ER - TY - JOUR T1 - The Impact of Full Time Student Teaching on Preservice Teachers' Conceptions of Mathematics Teaching and Learning AN - 61834092; EJ852383 AB - This study investigated the changes in conceptions on mathematics teaching and learning of preservice BScEd teachers after 12 weeks of full time teaching practice. Written answers to open ended questions administered at the beginning and end of student teaching were triangulated with interviews. The preservice teachers exhibited more differences in conceptions on teaching than on learning mathematics. Students' age, class level, the nature of mathematical content and the need to match students' discursive skills with their achievement in written work influenced the preservice teachers' pedagogical and epistemological beliefs. The paper postulates some possible factors that influenced preservice teachers' conceptions on mathematics instruction. (Contains 1 table.) JF - Mathematics Teacher Education and Development AU - Nyaumwe, Lovemore Y1 - 2004 PY - 2004 DA - 2004 SP - 19 EP - 32 PB - Mathematics Education Research Group of Australasia. GPO Box 2747, Adelaide SA 5001, Australia. Tel: +61-8-8363-0288; Fax: +61-8-8362-9288; e-mail: mted@merga.net.au; Web site: http://www.merga.net.au/ VL - 6 SN - 1442-3901, 1442-3901 KW - Zimbabwe KW - ERIC, Current Index to Journals in Education (CIJE) KW - Higher Education KW - Foreign Countries KW - Student Attitudes KW - Student Teaching KW - Mathematics Instruction KW - Preservice Teachers KW - Knowledge Base for Teaching KW - Attitude Change KW - Teaching Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61834092?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 N1 - SubjectsTermNotLitGenreText - 4109 4335; 8145 1806 10278 8016 4542; 6419 5242; 10268 8144 10507 8260 3150; 10621 3227 6582; 10181 730; 727 1387; 5674 ER - TY - JOUR T1 - Ethics in Community Based Elder Care AN - 61518468; 200403854 JF - Journal of Social Work in Long-Term Care AU - Congress, Elaine AU - Congress, Elaine Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 108 EP - 109 VL - 3 IS - 1 SN - 1533-2624, 1533-2624 KW - article KW - 6127: social gerontology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61518468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Journal+of+Social+Work+in+Long-Term+Care&rft.atitle=Ethics+in+Community+Based+Elder+Care&rft.au=Congress%2C+Elaine%3BHolstein%2C+Martha&rft.aulast=Congress&rft.aufirst=Elaine&rft.date=2004-01-01&rft.volume=3&rft.issue=1&rft.spage=108&rft.isbn=&rft.btitle=&rft.title=Journal+of+Social+Work+in+Long-Term+Care&rft.issn=15332624&rft_id=info:doi/ LA - English DB - Social Services Abstracts N1 - Date revised - 2007-05-01 N1 - SuppNotes - Edition date: 2003. N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Data Mining and the Search for Security: Challenges for Connecting the Dots and Databases AN - 60714526; 200506083 AB - Data mining is emerging as one of the key features of many homeland security initiatives. Often used as a means for detecting fraud, assessing risk, & product retailing, data mining involves the use of data analysis tools to discover previously unknown, valid patterns & relationships in large data sets. In the context of homeland security, data mining is often viewed as a potential means to identify terrorist activities, such as money transfers & communications, & to identify & track individual terrorists themselves, such as through travel & immigration records. However, compared to earlier uses of data mining by government, some of the homeland security data mining applications represent a significant expansion in the quantity & scope of data to be analyzed. Three of the higher profile initiatives include the now defunct Terrorism Information Awareness (TIA) project, the recently canceled Computer-Assisted Passenger Prescreening System II (CAPPS II), & the Multistate Anti-Terrorism Information Exchange (MATRIX) pilot project. This article examines the evolving nature of data mining for homeland security purposes, the limitations of data mining, & some of the issues raised by its expanding use, including data quality, interoperability, mission creep, & privacy. [Copyright 2004 Elsevier Inc.] JF - Government Information Quarterly AU - Seifert, Jeffrey W AD - Congressional Research Service, Library Congress, Washington, DC jseifert@crs.loc.gov Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 461 EP - 480 VL - 21 IS - 4 SN - 0740-624X, 0740-624X KW - Terrorism KW - Privacy KW - Data Processing KW - United States of America KW - Program Evaluation KW - Data Banks KW - National Security KW - article KW - 9043: methodology and research technology; research methods and models KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60714526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Government+Information+Quarterly&rft.atitle=Data+Mining+and+the+Search+for+Security%3A+Challenges+for+Connecting+the+Dots+and+Databases&rft.au=Seifert%2C+Jeffrey+W&rft.aulast=Seifert&rft.aufirst=Jeffrey&rft.date=2004-01-01&rft.volume=21&rft.issue=4&rft.spage=461&rft.isbn=&rft.btitle=&rft.title=Government+Information+Quarterly&rft.issn=0740624X&rft_id=info:doi/10.1016%2Fj.giq.2004.08.006 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - GIQUEU N1 - SubjectsTermNotLitGenreText - United States of America; National Security; Data Banks; Data Processing; Terrorism; Program Evaluation; Privacy DO - http://dx.doi.org/10.1016/j.giq.2004.08.006 ER - TY - JOUR T1 - Homeland Security and Information Sharing: Federal Policy Considerations AN - 60713953; 200506072 AB - Inadequate information sharing by federal entities was a factor in the terrorist attacks of September 11, 2001. Among the responses to this shortcoming is Section 892 of the Homeland Security Act of 2002, which mandates the prescription of homeland security information-sharing procedures by the President. This responsibility has been delegated to the Secretary of Homeland Security, & the required procedures are expected to be issued in some form, preliminary or final, during the summer of 2004. Those developing these procedures will encounter what one information security expert describes as "a series of bureaucratic fiefdoms, a veritable 'patchwork quilt,' that has come about as a consequence of a hodgepodge of laws, regulations & directives with respect to how the Federal Government handles & discloses information." Examined in this review are some of the discernable uncertainties in the creation of the information-sharing procedures, & some of the policy considerations involved. [Copyright 2004 Elsevier Inc.] JF - Government Information Quarterly AU - Relyea, Harold C AD - Congressional Research Service, Library Congress, Washington, DC hrelyea@crs.loc.gov Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 420 EP - 438 VL - 21 IS - 4 SN - 0740-624X, 0740-624X KW - Information KW - Terrorism KW - Cooperation KW - Intergovernmental Relations KW - United States of America KW - Interorganizational Networks KW - National Security KW - Legislation KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60713953?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Government+Information+Quarterly&rft.atitle=Homeland+Security+and+Information+Sharing%3A+Federal+Policy+Considerations&rft.au=Relyea%2C+Harold+C&rft.aulast=Relyea&rft.aufirst=Harold&rft.date=2004-01-01&rft.volume=21&rft.issue=4&rft.spage=420&rft.isbn=&rft.btitle=&rft.title=Government+Information+Quarterly&rft.issn=0740624X&rft_id=info:doi/10.1016%2Fj.giq.2004.08.007 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - GIQUEU N1 - SubjectsTermNotLitGenreText - United States of America; Terrorism; Legislation; National Security; Information; Intergovernmental Relations; Interorganizational Networks; Cooperation DO - http://dx.doi.org/10.1016/j.giq.2004.08.007 ER - TY - JOUR T1 - Congress Online: Assessing and Improving Capitol Hill Web Sites AN - 60701878; 200516185 JF - Political Communication AU - Kedrowski, Karen M AU - Kedrowski, Karen M Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 119 EP - 124 VL - 21 IS - 1 SN - 1058-4609, 1058-4609 KW - article KW - 9181: politics and communication; politics and communication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60701878?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Political+Communication&rft.atitle=Congress+Online%3A+Assessing+and+Improving+Capitol+Hill+Web+Sites&rft.au=Kedrowski%2C+Karen+M%3BCongress+Online+Project&rft.aulast=Kedrowski&rft.aufirst=Karen&rft.date=2004-01-01&rft.volume=21&rft.issue=1&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=Political+Communication&rft.issn=10584609&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - SuppNotes - Edition date: 2002. N1 - Last updated - 2016-09-28 N1 - CODEN - PLCMEM ER - TY - JOUR T1 - Electronic Government: Government Capability and Terrorist Resource AN - 60688407; 200506011 AB - The federal government's war on terrorism has heightened understanding & appreciation of the many facets of electronic government. Electronic government is used as a resource in the war on terrorism, helping to prevent & prepare for attacks. It might also prove useful in recovering from attacks. Unfortunately, e-government itself is a likely target for terrorists. Cyber intrusions into government Web sites & damage to, or destruction of, infrastructure, whether a computer system or an electrical grid that supplies power, could impair e-government. E-government is also attractive as a potential target for the information it provides, information that enemies of the US could use in identifying weaknesses & planning attacks. While the Bush Administration has developed a comprehensive policy, based on a market model, for facilitating the use & effectiveness of e-government, its approach to e-government security, particularly in the area of Web content, has been ad hoc. Soon after the September 11, 2001, attacks, federal agencies began scrubbing their Web sites, an effort that has implications for the notion, & practice, of having a well-informed citizenry. [Copyright 2004 Elsevier Inc.] JF - Government Information Quarterly AU - Halchin, L Elaine AD - Congressional Research Service, Library Congress, Washington, DC ehalchin@crs.loc.gov Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 406 EP - 419 VL - 21 IS - 4 SN - 0740-624X, 0740-624X KW - Telecommunications Policy KW - Defense Policy KW - Information Technology KW - Terrorism KW - Freedom of Information KW - United States of America KW - National Security KW - Governance KW - Internet KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60688407?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Government+Information+Quarterly&rft.atitle=Electronic+Government%3A+Government+Capability+and+Terrorist+Resource&rft.au=Halchin%2C+L+Elaine&rft.aulast=Halchin&rft.aufirst=L&rft.date=2004-01-01&rft.volume=21&rft.issue=4&rft.spage=406&rft.isbn=&rft.btitle=&rft.title=Government+Information+Quarterly&rft.issn=0740624X&rft_id=info:doi/10.1016%2Fj.giq.2004.08.002 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - GIQUEU N1 - SubjectsTermNotLitGenreText - Terrorism; United States of America; Information Technology; Internet; Governance; National Security; Defense Policy; Telecommunications Policy; Freedom of Information DO - http://dx.doi.org/10.1016/j.giq.2004.08.002 ER - TY - JOUR T1 - Constituents and Your Web Site: What Citizens Want to See on Congressional Web Sites AN - 60677419; 200516186 JF - Political Communication AU - Kedrowski, Karen M AU - Kedrowski, Karen M Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 119 EP - 124 VL - 21 IS - 1 SN - 1058-4609, 1058-4609 KW - article KW - 9181: politics and communication; politics and communication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60677419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Political+Communication&rft.atitle=Constituents+and+Your+Web+Site%3A+What+Citizens+Want+to+See+on+Congressional+Web+Sites&rft.au=Kedrowski%2C+Karen+M%3BCongress+Online+Project&rft.aulast=Kedrowski&rft.aufirst=Karen&rft.date=2004-01-01&rft.volume=21&rft.issue=1&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=Political+Communication&rft.issn=10584609&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - SuppNotes - Edition date: 2001. N1 - Last updated - 2016-09-28 N1 - CODEN - PLCMEM ER - TY - JOUR T1 - Do You Know Where Your Information Is in the Homeland Security Era? AN - 60672200; 200507737 AB - Why should we care about our information? As we enter the era of homeland security, one can see a new premium being placed on the role of information to fight terrorism while the policies related to government information practices are in a state of flux. Exactly how these policies are evolving is not always clear. Yet, the decisions being made now will likely have a lasting impact for years to come. In an attempt to better understand dynamics underlying these changes, a number of questions regarding the use, control, & protection of personal & public information are posed in this introduction to the symposium issue. We also review some of the major themes examined in greater detail by the contributors to the symposium. These issues include the role of e-government in homeland security, the emphasis on information sharing, the emergence of new information classification categories, the growth of data mining, & the eroding sense of privacy. While a number of reasons can be offered to justify one policy alternative over another, we conclude that the importance of these issues suggests that they are best debated & implemented during a time not under duress when decisions made in the heat of the moment can lead to unintended consequences. [Copyright 2004 Elsevier Inc.] JF - Government Information Quarterly AU - Seifert, Jeffrey W AU - Relyea, Harold C AD - Congressional Research Service, Library Congress, Washington, DC jseifert@crs.loc.gov Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 399 EP - 405 VL - 21 IS - 4 SN - 0740-624X, 0740-624X KW - Information KW - Terrorism KW - Freedom of Information KW - Privacy KW - Governance KW - National Security KW - article KW - 9221: politics and society; politics and society UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60672200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Government+Information+Quarterly&rft.atitle=Do+You+Know+Where+Your+Information+Is+in+the+Homeland+Security+Era%3F&rft.au=Seifert%2C+Jeffrey+W%3BRelyea%2C+Harold+C&rft.aulast=Seifert&rft.aufirst=Jeffrey&rft.date=2004-01-01&rft.volume=21&rft.issue=4&rft.spage=399&rft.isbn=&rft.btitle=&rft.title=Government+Information+Quarterly&rft.issn=0740624X&rft_id=info:doi/10.1016%2Fj.giq.2004.08.001 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - GIQUEU N1 - SubjectsTermNotLitGenreText - Terrorism; National Security; Information; Freedom of Information; Governance; Privacy DO - http://dx.doi.org/10.1016/j.giq.2004.08.001 ER - TY - JOUR T1 - Email Overload in Congress: Managing a Communications Crisis AN - 60671767; 200516187 JF - Political Communication AU - Kedrowski, Karen M AU - Kedrowski, Karen M Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 119 EP - 124 VL - 21 IS - 1 SN - 1058-4609, 1058-4609 KW - article KW - 9089: government/political systems; legislatures KW - 9181: politics and communication; politics and communication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60671767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Political+Communication&rft.atitle=Email+Overload+in+Congress%3A+Managing+a+Communications+Crisis&rft.au=Kedrowski%2C+Karen+M%3BCongress+Online+Project&rft.aulast=Kedrowski&rft.aufirst=Karen&rft.date=2004-01-01&rft.volume=21&rft.issue=1&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=Political+Communication&rft.issn=10584609&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - SuppNotes - Edition date: 2001. N1 - Last updated - 2016-09-28 N1 - CODEN - PLCMEM ER - TY - JOUR T1 - Privacy, Confidentiality, and Data Sharing: Issues and Distinctions AN - 60652880; 200423210 AB - Argues that the US government should inform citizens concerning what it does with the personal information they share with the government. Privacy legislation is very difficult to write because it deals with two elements that are highly variable -- individual's attitudes are subject to external events & vary across time, & an agency's definition of confidentiality also varies across time & may be different from other agencies. This article reviews privacy legislation passed by the US Congress between 1970 & 2000, with emphasis on the 104th through 107th Congresses, to examine the Congressional perception of citizen's rights in respect to the information they voluntarily offer about themselves to the government. The author discusses the extent of data sharing allowed by Title V of the Electronic Government Act, details concerning data sharing practices, the distinction between information collected voluntarily & that collected under penalty of law, & offers guidelines for implementation of Title V. 1 Appendix. L. A. Hoffman JF - Government Information Quarterly AU - McMillen, David Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 359 EP - 382 VL - 21 IS - 3 SN - 0740-624X, 0740-624X KW - Information KW - Government Agencies KW - Information Dissemination KW - Government Policy KW - Privacy KW - United States of America KW - Legislation KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60652880?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Government+Information+Quarterly&rft.atitle=Privacy%2C+Confidentiality%2C+and+Data+Sharing%3A+Issues+and+Distinctions&rft.au=McMillen%2C+David&rft.aulast=McMillen&rft.aufirst=David&rft.date=2004-01-01&rft.volume=21&rft.issue=3&rft.spage=359&rft.isbn=&rft.btitle=&rft.title=Government+Information+Quarterly&rft.issn=0740624X&rft_id=info:doi/10.1016%2Fj.giq.2004.05.001 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 2 N1 - Last updated - 2016-09-28 N1 - CODEN - GIQUEU N1 - SubjectsTermNotLitGenreText - United States of America; Legislation; Information; Information Dissemination; Privacy; Government Agencies; Government Policy DO - http://dx.doi.org/10.1016/j.giq.2004.05.001 ER - TY - JOUR T1 - Possible Pathways for Iraq's Political Evolution AN - 60601124; 200506028 AB - Details alternative scenarios for Iraq's political development as a way to make sense of current trends. The "puppet government" model is similar to what is currently in place in Iraq & would see a weak government of questionable legitimacy backed by the US. The strongman model is essentially the form of governance experienced for 24 years under Saddam Hussein & would involve current Prime Minister Allawi's keeping of power & US support of him, which would run counter to the policy goal of regional democratization. The election-driven model represents the transition required to fulfill US aspirations in the Middle East, although it is not without problems. The failed-state model or civil war scenario, while not likely, is possible given the insurgency & would represent a transition phase to another model. The power-sharing model entails the major factions reaching a compromise to govern in partnership & would not result in genuine democratization. However, this last model is seen as the most likely to end the insurgency & produce stability, although it does not fit with US policy goals or with the plans of major Shiite factions, who stand to benefit from an election-driven model. J. Zendejas JF - Middle East Policy AU - Katzman, Kenneth AD - Congressional Research Service Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 58 EP - 64 VL - 11 IS - 4 SN - 1061-1924, 1061-1924 KW - Political Systems KW - Democracy KW - Political Development KW - Iraq KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60601124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Middle+East+Policy&rft.atitle=Possible+Pathways+for+Iraq%27s+Political+Evolution&rft.au=Katzman%2C+Kenneth&rft.aulast=Katzman&rft.aufirst=Kenneth&rft.date=2004-01-01&rft.volume=11&rft.issue=4&rft.spage=58&rft.isbn=&rft.btitle=&rft.title=Middle+East+Policy&rft.issn=10611924&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Iraq; Democracy; Political Development; Political Systems ER - TY - JOUR T1 - Indonesian Masculinities: Images of Men in Indonesian TV Advertising AN - 60040294; 200616130 AB - Expands upon previous feminist scholarship on gendered representations to suggest that, although images of men in Indonesian TV commercials reinforce societal norms of male dominance, they also represent women as both earners & spenders in the public sphere. It is also contended that TV ads reveal the emergence of a negative or contemptuous attitude toward men in contemporary Indonesian popular culture. The trend to replace misogyny with a culture of "misandry" is examined & illustrated by such TV ads as a Hexos (throat lozenge) commercial that features a man screaming hysterically at the sight of a cockroach. Attention is given to the proliferation of women's groups that have appeared since the 1998 resignation of President Suharto & Indonesia's transition toward a more democratic social & political system. The possibility that misandry could be counter-productive for women's groups is addressed. It is concluded that hegemonic masculinity in Indonesia is fragile & TV commercials indicate that masculinity is in transition or, at the very least, is being perceived differently than it was in earlier decades. References. J. Lindroth JF - RIMA: Review of Indonesian and Malaysian Affairs AU - Clark, Marshall AD - School Asian Languages & Studies, U Tasmania Marshall.Clark@utas.edu.au Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 9 EP - 37 PB - RIMA, GPO Box 1820, Canberra ACT 2601 Australia VL - 38 IS - 2 SN - 0815-7251, 0815-7251 KW - Social Attitudes KW - Opposite Sex Relations KW - Television KW - Indonesia KW - Sex Role Attitudes KW - Advertising KW - Sex Stereotypes KW - article KW - 2983: feminist/gender studies; sociology of gender & gender relations KW - 0749: social change and economic development; market structures & consumer behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60040294?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.atitle=Indonesian+Masculinities%3A+Images+of+Men+in+Indonesian+TV+Advertising&rft.au=Clark%2C+Marshall&rft.aulast=Clark&rft.aufirst=Marshall&rft.date=2004-01-01&rft.volume=38&rft.issue=2&rft.spage=9&rft.isbn=&rft.btitle=&rft.title=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.issn=08157251&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 61 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Indonesia; Television; Advertising; Opposite Sex Relations; Sex Stereotypes; Sex Role Attitudes; Social Attitudes ER - TY - JOUR T1 - Chapter 7. National Defence Reform and the African Union AN - 60032133; 200935233 AB - Significant strides were made in the African security sector during 2003. At the political-strategic level certain conflicts edged closer to resolution, albeit falteringly, as demonstrated by the relative successes of the facilitated peace processes under way in Angola, Burundi, the Democratic Republic of the Congo (DRC), Liberia and Sudan. Recently installed military governments, so long the bane of many developing countries, found themselves under immense pressure from the African Union (AU), various African sub-regional groupings and key states in their regions to disengage from the political process. The return to barracks by the armed forces of the Central African Republic, Cote d'Ivoire and Guinea-Bissau was primarily the result of this pressure. A strategic shift is taking place away from the limited politics of diplomatic engagement to the creation of more robust African peacekeeping and intervention capabilities. Both the AU and certain sub-regional organizations, such as the Economic Community of West African States, the Intergovernmental Authority on Development and the Southern African Development Community, are beginning to fashion peace and security strategies and structures that envisage a substantially enhanced role for these bodies in the management and resolution of African conflicts. An incrementally widening circle of national governments have initiated security sector reviews, White Paper processes and restructuring initiatives designed to enhance the professionalism of their security forces and their accountability to elected civil authorities. These initiatives and are evident in countries as diverse as Ghana, Mozambique, Rwanda, Senegal, Sierra Leone, South Africa and Uganda. All these initiatives, national and regional, are responding to international donor pressure. However, structural tensions continue to pervade African societies and their respective polities. The successful management of conflicts in Angola, Burundi, the DRC, Liberia, Rwanda and Sudan had been preceded and, in some cases, presaged by deep-seated political, economic, structural and, in certain instances, ethnic conflict that had its roots in the pre-colonial and colonial history of Africa. There is no universal reconstruction template that can be applied to post-conflict societies. Whether restructuring of national armies, reduction of foreign debt, privatization of public enterprises or reduction of poverty is prioritized as the key issue to be addressed, such goals can only be achieved by nationals of the country concerned based on the unique correlation of forces (physical and psychological) that pertains in that country at any given time. While the institution of the AU, the New Partnership for Africa's Development (NEPAD), and the activation of the various sub-regional bodies represent a positive step forward in the direction of a practical pan-Africanism, it is also important to stress that immense challenges face their operationalization. Already, many African countries have been tardy about submitting themselves to the African Peer Review Process (South Africa and Ghana being the first countries to do so) and differences exist between Egypt and South Africa about in which of their respective countries the first Pan-African Parliament will be located. Further challenges include the following: (1) building capacity at the national levels of government, without which sub-regional organizations will be rendered toothless; (2) ensuring that a synergy at both organizational and policy level exists between national, sub-regional and organizational bodies and that appropriate resources are identified for their different tasks; (3) avoiding the risk of undue competition and rivalry between the 'superpowers' of the continent (Algeria, Egypt, Nigeria and South Africa) for the dominant positions in African organizations; (4) avoiding the danger of over-extending capabilities -- both civil and military; and (5) resolving the enduring and perennial problem of initiating too wide a range of initiatives without having the resources, capacity and planning ability to complete them all. Adapted from the source document. JF - SIPRI Yearbook AU - Williams, Rocky AD - African National Congress of South Africa, Umkhonto Y1 - 2004///0, PY - 2004 DA - 0, 2004 PB - Oxford University Press, UK SN - 0953-0282, 0953-0282 KW - Pan-Africanism KW - Defense Policy KW - International Cooperation KW - Reconstruction KW - Africa KW - Armed Forces KW - article KW - 9063: international relations; international relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60032133?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=SIPRI+Yearbook&rft.atitle=Chapter+7.+National+Defence+Reform+and+the+African+Union&rft.au=Williams%2C+Rocky&rft.aulast=Williams&rft.aufirst=Rocky&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=SIPRI+Yearbook&rft.issn=09530282&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2009-12-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Africa; Defense Policy; Armed Forces; Reconstruction; Pan-Africanism; International Cooperation ER - TY - JOUR T1 - Global Influence, National Politics and Local Identity in Central Javanese Theatre AN - 60002923; 200614848 AB - An exploration of Indonesian theater in the Central Javanese city of Yogyakarta focuses on how theatrical activities have evolved since the late 1970s. The Yogyakarta experience challenges the stereotypical view of a vulnerable local culture that is helpless alongside powerful global forces. The important Javanese art form of ketoprak is described, along with the new freedom for experimentation in the 1970s-1980s that was represented by theatrical representations of Javanese cultural traditions as flawed, corrupt, & exploitive; & changes that occurred with the rapid capitalist development of the 1980s-1990s. Ketoprak performers & modern theater actors worked together to produce a subversively humorous style of dramatic phenomenon called ketoprak plesedan. Although short lived, important legacies of the plesedan craze include a model of humorous parody; collaboration between old & new theatrical forms; engagement with political developments; & interaction between local, national, & global forces. It is concluded that theater in Yogyakarta represents a new ideological value of democratic participation as well as an expression of ambiguities related to Javanese traditions. References. J. Lindroth JF - RIMA: Review of Indonesian and Malaysian Affairs AU - Hatley, Barbara AD - School Asian Languages & Studies, U Tasmania utas.edu.au Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 63 EP - 99 PB - RIMA, GPO Box 1820, Canberra ACT 2601 Australia VL - 38 IS - 2 SN - 0815-7251, 0815-7251 KW - Countercultures KW - Theater Arts KW - Indonesia KW - Social Evolution KW - Cultural Change KW - article KW - 0513: culture and social structure; culture (kinship, forms of social organization, social cohesion & integration, & social representations) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60002923?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.atitle=Global+Influence%2C+National+Politics+and+Local+Identity+in+Central+Javanese+Theatre&rft.au=Hatley%2C+Barbara&rft.aulast=Hatley&rft.aufirst=Barbara&rft.date=2004-01-01&rft.volume=38&rft.issue=2&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.issn=08157251&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 18 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Indonesia; Theater Arts; Social Evolution; Cultural Change; Countercultures ER - TY - BOOK T1 - Native American Fish and Wildlife Resources Management Act: hearing on S. 2301 to improve the management of Indian fish and wildlife and gathering resources, April 29, 2004 T2 - 108th Cong., 2d sess. S. hearing 108-563 AN - 59996332; 2004-1002440 AB - Discusses draft bill for tribal management of resources on tribal lands; text of bill. JF - Superintendent of Documents, 2004. iii+149 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+149 PB - Superintendent of Documents KW - Conservation of resources -- United States -- Legislation KW - Wildlife conservation -- United States -- Legislation KW - United States -- Native races -- Legal status, laws, etc. KW - Environmental law -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59996332?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B149&rft.isbn=&rft.btitle=Native+American+Fish+and+Wildlife+Resources+Management+Act%3A+hearing+on+S.+2301+to+improve+the+management+of+Indian+fish+and+wildlife+and+gathering+resources%2C+April+29%2C+2004&rft.title=Native+American+Fish+and+Wildlife+Resources+Management+Act%3A+hearing+on+S.+2301+to+improve+the+management+of+Indian+fish+and+wildlife+and+gathering+resources%2C+April+29%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Final rule on overtime pay: hearing, May 4, 2004 T2 - 108th Cong., 2d sess. Special hearing S. hearing 108-542 AN - 59994720; 2004-1002420 AB - Discusses regulation to strengthen overtime protections of the Fair Labor Standards Act by examining changes in current regulations, employment status, according to salary, and definitions of job titles and duties; US. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+61 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+61 PB - Superintendent of Documents KW - Labor standards -- United States KW - United States -- Labor department KW - Wages and salaries -- United States -- Legislation KW - United States -- Labor policy KW - Overtime -- United States -- Legislation KW - Hours of labor -- United States -- Legislation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59994720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B61&rft.isbn=&rft.btitle=Final+rule+on+overtime+pay%3A+hearing%2C+May+4%2C+2004&rft.title=Final+rule+on+overtime+pay%3A+hearing%2C+May+4%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Terrorism: radical Islamic influence of chaplaincy of the U.S. military and prisons: hearing, October 14, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-44 S. hearing 108-443 AN - 59993657; 2004-0905660 JF - Superintendent of Documents, 2004. iii+101 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+101 PB - Superintendent of Documents KW - Chaplains, Prison -- United States KW - Service men -- Religion KW - Radicalism -- United States KW - United States -- Prisons bureau KW - Terrorism -- United States KW - Prisoners -- Religion KW - Islam and politics -- United States KW - United States -- Defense department KW - Chaplains, Military -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59993657?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B101&rft.isbn=&rft.btitle=Terrorism%3A+radical+Islamic+influence+of+chaplaincy+of+the+U.S.+military+and+prisons%3A+hearing%2C+October+14%2C+2003&rft.title=Terrorism%3A+radical+Islamic+influence+of+chaplaincy+of+the+U.S.+military+and+prisons%3A+hearing%2C+October+14%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - America after 9/11: freedom preserved or freedom lost? hearing, November 18, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-53 S. hearing 108-482 AN - 59991736; 2004-1001460 AB - Discusses concerns that abuses of civil liberties and privacy have occurred under the Patriot Act and related Bush administration post 9/11 anti-terrorist legislation. JF - Superintendent of Documents, 2004. iv+371 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+371 PB - Superintendent of Documents KW - Counterterrorism -- United States -- Legislation KW - Internal security -- United States KW - Civil rights -- United States KW - September 11, 2001 attacks KW - Counterterrorism -- Legal aspects KW - Privacy -- Legal aspects KW - United States -- Law enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59991736?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B371&rft.isbn=&rft.btitle=America+after+9%2F11%3A+freedom+preserved+or+freedom+lost%3F+hearing%2C+November+18%2C+2003&rft.title=America+after+9%2F11%3A+freedom+preserved+or+freedom+lost%3F+hearing%2C+November+18%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Self-dealing and breach of duty at ULLICO, Inc.: majority staff report, June 2, 2004 T2 - 108th Cong., 2d sess. S. print 108-45 Com. print AN - 59986263; 2004-1007290 AB - Examines questionable stock transactions by officers and directors at the parent company of Union Labor Life Insurance Company. JF - Superintendent of Documents, 2004. iv+1641 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+1641 PB - Superintendent of Documents KW - United States -- Finance -- Regulation KW - Directors -- Ethics KW - Trade unions -- Finance KW - ULLICO Inc. KW - Labor officials -- Ethics KW - Securities fraud -- United States KW - United States -- Labor sector UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59986263?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B1641&rft.isbn=&rft.btitle=Self-dealing+and+breach+of+duty+at+ULLICO%2C+Inc.%3A+majority+staff+report%2C+June+2%2C+2004&rft.title=Self-dealing+and+breach+of+duty+at+ULLICO%2C+Inc.%3A+majority+staff+report%2C+June+2%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Annual report: fiscal year, 2003 AN - 59972576; 2004-1005200 AB - Performance, productivity, services, research, and other activities of the Congressional Research Service (CRS). JF - United States Congressional Research Service, 2004. Y1 - 2004///0, PY - 2004 DA - 0, 2004 PB - United States Congressional Research Service KW - United States -- Library of Congress -- Congressional research service KW - Government information -- United States KW - Legislative research -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59972576?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Annual+report%3A+fiscal+year%2C+2003&rft.title=Annual+report%3A+fiscal+year%2C+2003&rft.issn=&rft_id=info:doi/ L2 - http://www.loc.gov/crsinfo/CRS03_AnnRpt.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Cong Research Service N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - An overview of the Senate Code of Conduct and related laws, July 2004 T2 - 108th Cong., 2d sess. S. print 108-49 AN - 59969413; 2004-0910280 JF - Superintendent of Documents, 2004. 16 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 16 PB - Superintendent of Documents KW - Political ethics -- United States KW - United States -- Senate -- Rules and practice KW - Legislators -- Ethics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59969413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=An+overview+of+the+Senate+Code+of+Conduct+and+related+laws%2C+July+2004&rft.title=An+overview+of+the+Senate+Code+of+Conduct+and+related+laws%2C+July+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs N1 - Document feature - table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Elder abuse, neglect, and exploitation: are we doing enough? hearing, September 24, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-43 S. hearing 108-445 AN - 59958494; 2004-1001310 AB - Discusses victimization of the elderly through mail fraud and telemarketing and financial scams, incidents of physical abuse, initiatives of the US Postal Inspection Service and the Social Security Administration to combat abuse, the need for increased law enforcement, and the proposed Elder Justice Act. JF - Superintendent of Documents, 2004. iii+100 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+100 PB - Superintendent of Documents KW - Telephone selling -- Corrupt practices KW - United States -- Social security administration KW - Old age -- Crimes against KW - Fraud -- United States KW - United States -- Postal inspection service KW - Elder abuse -- United States KW - United States -- Law enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59958494?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B100&rft.isbn=&rft.btitle=Elder+abuse%2C+neglect%2C+and+exploitation%3A+are+we+doing+enough%3F+hearing%2C+September+24%2C+2003&rft.title=Elder+abuse%2C+neglect%2C+and+exploitation%3A+are+we+doing+enough%3F+hearing%2C+September+24%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Agroterrorism: the threat to America's breadbasket: hearing, November 19, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-491 AN - 59958257; 2004-1000900 AB - Explores vulnerability of the agriculture and food industry to terrorist attacks, actions to defend against agroterrorism, and how prepared the US is to such an attack. JF - Superintendent of Documents, 2004. iv+166 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+166 PB - Superintendent of Documents KW - Food supply -- United States KW - Agriculture -- Safety measures KW - Bioterrorism -- United States KW - Food security -- United States KW - United States -- Agricultural sector KW - Counterterrorism -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59958257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B166&rft.isbn=&rft.btitle=Agroterrorism%3A+the+threat+to+America%27s+breadbasket%3A+hearing%2C+November+19%2C+2003&rft.title=Agroterrorism%3A+the+threat+to+America%27s+breadbasket%3A+hearing%2C+November+19%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Federal law enforcement personnel in the post September 11 era: how can we fix an imbalanced compensation system? joint hearing before the Subcommittee on Civil Service and Agency Organization and the Subcommittee on Criminal Justice, Drug Policy, and Human Resources of the Committee on Government Reform, House of Representatives, July 23, 2003 T2 - 108th Cong., 1st sess. Serial no. 108-83 AN - 59956687; 2004-0607320 AB - Also available on the Internet. JF - Superintendent of Documents, 2004. vi+283 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - vi+283 PB - Superintendent of Documents KW - Internal security -- United States KW - Wages and salaries -- Police KW - United States -- Law enforcement -- Finance KW - Wages and salaries -- Government employees UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59956687?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=vi%2B283&rft.isbn=&rft.btitle=Federal+law+enforcement+personnel+in+the+post+September+11+era%3A+how+can+we+fix+an+imbalanced+compensation+system%3F+joint+hearing+before+the+Subcommittee+on+Civil+Service+and+Agency+Organization+and+the+Subcommittee+on+Criminal+Justice%2C+Drug+Policy%2C+and+Human+Resources+of+the+Committee+on+Government+Reform%2C+House+of+Representatives%2C+July+23%2C+2003&rft.title=Federal+law+enforcement+personnel+in+the+post+September+11+era%3A+how+can+we+fix+an+imbalanced+compensation+system%3F+joint+hearing+before+the+Subcommittee+on+Civil+Service+and+Agency+Organization+and+the+Subcommittee+on+Criminal+Justice%2C+Drug+Policy%2C+and+Human+Resources+of+the+Committee+on+Government+Reform%2C+House+of+Representatives%2C+July+23%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Anti-Semitism in Europe: hearing, October 22, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-370 AN - 59956200; 2004-0601780 AB - Discusses increased harassment and violent attacks against Jews, influence of the Israeli-Palestinian conflict and Muslim anti-Semitism on European attitudes, linkage of anti-Americanism with anti-Semitism, European law enforcement response, and initiatives of the Organization for Security and Cooperation in Europe (OSCE). Also available on the Internet. JF - Superintendent of Documents, 2004. iii+140 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+140 PB - Superintendent of Documents KW - Jews -- Crimes against KW - Europe -- Law enforcement KW - Anti-Semitism -- Islamic countries KW - Anti-Semitism -- Europe KW - Anti-Americanism -- Europe KW - Organization for security and cooperation in Europe KW - Israel -- Foreign opinion KW - Hate crimes -- Europe KW - Conflict -- Middle East UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59956200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B140&rft.isbn=&rft.btitle=Anti-Semitism+in+Europe%3A+hearing%2C+October+22%2C+2003&rft.title=Anti-Semitism+in+Europe%3A+hearing%2C+October+22%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Alaska Native Allotment Subdivision Act; Alaska Land Transfer Facilities Act; Ojito Wilderness Act; and Inventory and Management Program for Public Domain Lands; hearing, February 12, 2004 on S. 1421, S. 1649, S. 1466, S. 1910 T2 - 108th Cong., 2d sess. S. hearing 108-416 AN - 59956107; 2004-0612180 AB - Discusses bills concerning land transfers and allotment, healthy forests, and designating wilderness areas; Alaska; Oregon; New Mexico. JF - Superintendent of Documents, 2004. iii+72 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+72 PB - Superintendent of Documents KW - United States -- Native races -- Legal status, laws, etc. KW - Indians -- Land tenure KW - Land settlement -- United States KW - Land utilization -- United States KW - Tribes and tribal system -- Legal aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59956107?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B72&rft.isbn=&rft.btitle=Alaska+Native+Allotment+Subdivision+Act%3B+Alaska+Land+Transfer+Facilities+Act%3B+Ojito+Wilderness+Act%3B+and+Inventory+and+Management+Program+for+Public+Domain+Lands%3B+hearing%2C+February+12%2C+2004+on+S.+1421%2C+S.+1649%2C+S.+1466%2C+S.+1910&rft.title=Alaska+Native+Allotment+Subdivision+Act%3B+Alaska+Land+Transfer+Facilities+Act%3B+Ojito+Wilderness+Act%3B+and+Inventory+and+Management+Program+for+Public+Domain+Lands%3B+hearing%2C+February+12%2C+2004+on+S.+1421%2C+S.+1649%2C+S.+1466%2C+S.+1910&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Is intellectual diversity an endangered species on America's college campuses? on examining intellectural diversity on America's college campuses, focusing on the problem of freedom of expression, politicized instruction, and core curricula: hearing, October 29, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-380 AN - 59955541; 2004-0611330 AB - Discusses concerns regarding replacement of traditional and educationally sound courses with trendy, uniform curricula lacking intellectual rigor, campus speech codes inhibiting students' First Amendment rights, and a pronounced left wing faculty bias that affects instruction and inhibits differing viewpoints; implications for educational quality. JF - Superintendent of Documents, 2004. iii+57 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+57 PB - Superintendent of Documents KW - Colleges and universities -- Courses of study KW - United States -- Educational sector KW - Right and Left -- United States KW - Intellectual liberty -- United States KW - Academic freedom -- United States KW - College students -- United States KW - Freedom of speech -- United States KW - College teachers -- Political attitudes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59955541?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B57&rft.isbn=&rft.btitle=Is+intellectual+diversity+an+endangered+species+on+America%27s+college+campuses%3F+on+examining+intellectural+diversity+on+America%27s+college+campuses%2C+focusing+on+the+problem+of+freedom+of+expression%2C+politicized+instruction%2C+and+core+curricula%3A+hearing%2C+October+29%2C+2003&rft.title=Is+intellectual+diversity+an+endangered+species+on+America%27s+college+campuses%3F+on+examining+intellectural+diversity+on+America%27s+college+campuses%2C+focusing+on+the+problem+of+freedom+of+expression%2C+politicized+instruction%2C+and+core+curricula%3A+hearing%2C+October+29%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Then and now: an update on the Bush administration's competitive sourcing initiative: hearing, July 24, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-244 AN - 59955126; 2004-0607860 AB - Addresses federal employees' concern that agencies are conducting competitions simply to meet quotas, not because the private sector could do the work more effectively. JF - Superintendent of Documents, 2004. iii+279 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+279 PB - Superintendent of Documents KW - Government employees -- United States KW - United States -- Public sector KW - Government competition with business -- United States KW - Outsourcing -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59955126?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B279&rft.isbn=&rft.btitle=Then+and+now%3A+an+update+on+the+Bush+administration%27s+competitive+sourcing+initiative%3A+hearing%2C+July+24%2C+2003&rft.title=Then+and+now%3A+an+update+on+the+Bush+administration%27s+competitive+sourcing+initiative%3A+hearing%2C+July+24%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - HIPAA medical privacy and transition rules: overkill or overdue? hearing, September 23, 2003 T2 - 108th Cong., 1st sess. Serial no. 108-23 S. hearing 108-256 AN - 59953341; 2004-0305130 AB - Discusses the Health Insurance Portability and Accountability Act, focusing on its requirements for medical information privacy and regulations for standardizing medical claims and transactions; US. JF - Superintendent of Documents, 2004. iii+171 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+171 PB - Superintendent of Documents KW - United States -- Health policy -- Legislation KW - Medical records -- Legal aspects KW - Health insurance -- Legal aspects KW - Privacy -- Legal aspects KW - Medical service -- Legal aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59953341?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B171&rft.isbn=&rft.btitle=HIPAA+medical+privacy+and+transition+rules%3A+overkill+or+overdue%3F+hearing%2C+September+23%2C+2003&rft.title=HIPAA+medical+privacy+and+transition+rules%3A+overkill+or+overdue%3F+hearing%2C+September+23%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Terrorism: growing Wahhabi influence in the United States: hearing, June 26, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-21 S. hearing 108-267 AN - 59952161; 2004-0506130 AB - Discusses links between the radical form of Islam which is the dominant sect in Saudi Arabia and al Qaeda, its jihadi ideology, the financing of extremist groups by a network of charitable front organizations funded and sponsored by the Saudi government, and Wahhabi penetration and recruitment activities within the American Muslim community. JF - Superintendent of Documents, 2004. iii+92 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+92 PB - Superintendent of Documents KW - Islam and politics KW - Terrorism -- Finance KW - Muslims -- Political activities KW - Saudi Arabia -- Government and politics KW - Wahhabiyah KW - Islam -- United States KW - Jihad KW - United States -- Government and politics KW - Al Qaeda UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59952161?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B92&rft.isbn=&rft.btitle=Terrorism%3A+growing+Wahhabi+influence+in+the+United+States%3A+hearing%2C+June+26%2C+2003&rft.title=Terrorism%3A+growing+Wahhabi+influence+in+the+United+States%3A+hearing%2C+June+26%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Fighting bioterrorism: using America's scientists and entrepreneurs to find solutions: hearing, February 5, 2002 T2 - 108th Cong., 2d sess. S. hearing 107-1028 AN - 59951227; 2004-0607400 AB - Focuses on how the federal government can better utilize private industry and its technical expertise in the continuing war against bioterrorist attacks; US. JF - Superintendent of Documents, 2004. iii+80 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+80 PB - Superintendent of Documents KW - Internal security -- United States KW - Science -- United States KW - Technology -- United States KW - Scientists -- United States KW - Bioterrorism -- Prevention KW - Entrepreneurs -- United States KW - Counterterrorism -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59951227?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B80&rft.isbn=&rft.btitle=Fighting+bioterrorism%3A+using+America%27s+scientists+and+entrepreneurs+to+find+solutions%3A+hearing%2C+February+5%2C+2002&rft.title=Fighting+bioterrorism%3A+using+America%27s+scientists+and+entrepreneurs+to+find+solutions%3A+hearing%2C+February+5%2C+2002&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Abstinence education; special hearing, February 16, 2004--Harrisburg, PA T2 - 108th Cong., 2d sess. S. hearing 108-385 AN - 59950257; 2004-0507160 AB - Discusses government-funded sexual abstinence programs targeted at teenagers; US. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+36 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+36 PB - Superintendent of Documents KW - United States -- Educational sector KW - United States -- Social conditions KW - Sex education -- United States KW - Sexual abstinence -- United States KW - Youth -- Sexual behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59950257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B36&rft.isbn=&rft.btitle=Abstinence+education%3B+special+hearing%2C+February+16%2C+2004--Harrisburg%2C+PA&rft.title=Abstinence+education%3B+special+hearing%2C+February+16%2C+2004--Harrisburg%2C+PA&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Solutions to the problem of health care transmission of HIV/AIDS in Africa: on examining solutions to the problem of health care transmission of HIV/AIDS in Africa, focusing on injection safety, blood safety, safe obstetrical delivery practices, and quality assurance in medical care: hearing, July 31, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-294 AN - 59949982; 2004-0605970 JF - Superintendent of Documents, 2004. iii+68 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+68 PB - Superintendent of Documents KW - Human immunodeficiency virus -- Africa KW - Public health -- Africa KW - Africa -- Health conditions KW - Blood transfusion -- Safety measures KW - Acquired immune deficiency syndrome -- Africa UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59949982?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B68&rft.isbn=&rft.btitle=Solutions+to+the+problem+of+health+care+transmission+of+HIV%2FAIDS+in+Africa%3A+on+examining+solutions+to+the+problem+of+health+care+transmission+of+HIV%2FAIDS+in+Africa%2C+focusing+on+injection+safety%2C+blood+safety%2C+safe+obstetrical+delivery+practices%2C+and+quality+assurance+in+medical+care%3A+hearing%2C+July+31%2C+2003&rft.title=Solutions+to+the+problem+of+health+care+transmission+of+HIV%2FAIDS+in+Africa%3A+on+examining+solutions+to+the+problem+of+health+care+transmission+of+HIV%2FAIDS+in+Africa%2C+focusing+on+injection+safety%2C+blood+safety%2C+safe+obstetrical+delivery+practices%2C+and+quality+assurance+in+medical+care%3A+hearing%2C+July+31%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Tribal contract support cost technical amendments: hearing, April 28, 2004 T2 - 108th Cong., 2d sess. S. hearing 108-540 AN - 59943348; 2004-1002450 AB - Testimony on S. 2172 to make technical amendments to the provisions of the Indian Self-Determination and Education Assistance Act relating to contract support costs, and for other purposes; US. JF - Superintendent of Documents, 2004. iii+50 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+50 PB - Superintendent of Documents KW - United States -- Native races -- Health KW - United States -- Health policy KW - Indians -- Health KW - United States -- Indian health service UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59943348?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B50&rft.isbn=&rft.btitle=Tribal+contract+support+cost+technical+amendments%3A+hearing%2C+April+28%2C+2004&rft.title=Tribal+contract+support+cost+technical+amendments%3A+hearing%2C+April+28%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Lessons learned--the Inspector General's report on the 9/11 detainees: hearing, June 25, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-19 S. hearing 108-257 AN - 59940787; 2004-0307600 JF - Superintendent of Documents, 2004. iii+111 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+111 PB - Superintendent of Documents KW - Civil rights -- United States KW - Detention of persons -- United States KW - September 11, 2001 attacks KW - Counterterrorism -- Legal aspects KW - United States -- Federal bureau of investigation KW - Aliens, Illegal -- Legal status, laws, etc. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59940787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B111&rft.isbn=&rft.btitle=Lessons+learned--the+Inspector+General%27s+report+on+the+9%2F11+detainees%3A+hearing%2C+June+25%2C+2003&rft.title=Lessons+learned--the+Inspector+General%27s+report+on+the+9%2F11+detainees%3A+hearing%2C+June+25%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Recycling: federal procurement and beverage container recycling programs: hearing, July 11, 2002 T2 - 107th Cong., 2d sess. S. hearing 107-1006 AN - 59940287; 2004-1001560 AB - Discusses concerns regarding the decline in aluminum recycling, whether federal agencies are maximizing their purchases of recycled content products, and a proposed national bottle deposit bill; some focus on paper, plastic, and glass recycling. JF - Superintendent of Documents, 2004. iii+132 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+132 PB - Superintendent of Documents KW - Aluminum industry -- Recycling KW - Recycling -- Regulation KW - Plastic containers -- Recycling KW - Glass container industry -- Recycling KW - Paper industry -- Recycling KW - United States -- Environmental policy KW - Waste management -- United States KW - Containers, Returnable -- United States KW - Beverage containers -- Recycling UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59940287?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B132&rft.isbn=&rft.btitle=Recycling%3A+federal+procurement+and+beverage+container+recycling+programs%3A+hearing%2C+July+11%2C+2002&rft.title=Recycling%3A+federal+procurement+and+beverage+container+recycling+programs%3A+hearing%2C+July+11%2C+2002&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Importation of exotic species: hearing, July 17, 2003, to examine the importation of exotic species and the impact on public health and safety T2 - 108th Cong., 1st sess. S. hearing 108-358 AN - 59939775; 2004-1000210 AB - Discusses the problem of diseases transmitted from animals, especially those imported from foreign countries, to humans (zoonotic diseases), as a result of globalization and global population growth; includes issues related to government regulation. JF - Superintendent of Documents, 2004. iii+93 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+93 PB - Superintendent of Documents KW - Animals -- Diseases and pests KW - Wildlife -- Export-import trade KW - Diseases -- International aspects KW - Public health -- United States KW - Public safety -- United States KW - United States -- Environmental policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59939775?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B93&rft.isbn=&rft.btitle=Importation+of+exotic+species%3A+hearing%2C+July+17%2C+2003%2C+to+examine+the+importation+of+exotic+species+and+the+impact+on+public+health+and+safety&rft.title=Importation+of+exotic+species%3A+hearing%2C+July+17%2C+2003%2C+to+examine+the+importation+of+exotic+species+and+the+impact+on+public+health+and+safety&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Combating gang violence in America: examining effective federal, state and local law enforcement strategies: hearing, September 17, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-42 S. hearing 108-429 AN - 59939385; 2004-1001940 AB - Discusses gang activities and prevention strategies; Chicago, Illinois; Washington, DC; New Jersey; New Orleans, Louisiana; California; Alexandria, Virginia. JF - Superintendent of Documents, 2004. iii+124 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+124 PB - Superintendent of Documents KW - Gangs -- United States KW - Federal and local government relations -- United States KW - Federal and state relations -- United States KW - Violence -- Prevention KW - Crime prevention -- United States KW - Juvenile delinquents -- United States KW - United States -- Law enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59939385?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B124&rft.isbn=&rft.btitle=Combating+gang+violence+in+America%3A+examining+effective+federal%2C+state+and+local+law+enforcement+strategies%3A+hearing%2C+September+17%2C+2003&rft.title=Combating+gang+violence+in+America%3A+examining+effective+federal%2C+state+and+local+law+enforcement+strategies%3A+hearing%2C+September+17%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Fiscal year 2005 budget: hearing, February 11, 2004, on president's budget request for Indian programs T2 - 108th Cong., 2d sess. S. hearing 108-420 AN - 59939281; 2004-1001280 AB - United States. JF - Superintendent of Documents, 2004. iv+195 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+195 PB - Superintendent of Documents KW - Indians KW - United States -- Finance KW - Budget, Government UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59939281?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B195&rft.isbn=&rft.btitle=Fiscal+year+2005+budget%3A+hearing%2C+February+11%2C+2004%2C+on+president%27s+budget+request+for+Indian+programs&rft.title=Fiscal+year+2005+budget%3A+hearing%2C+February+11%2C+2004%2C+on+president%27s+budget+request+for+Indian+programs&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Rural Teacher Housing Act: hearing, March 16, 2004 in Anchorage, Alaska T2 - 108th Cong., 2d sess. S. hearing 108-468 AN - 59937596; 2004-1001580 AB - Discusses proposed legislation to provide funding for rural school districts to address the housing shortage for teachers and thereby improve their recruitment and retention. JF - Superintendent of Documents, 2004. iii+48 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+48 PB - Superintendent of Documents KW - Alaska -- Educational sector KW - Alaska -- Rural conditions KW - Alaska -- Native races -- Education KW - Rural education -- United States -- Alaska KW - Indians -- Education KW - School districts -- United States -- Alaska KW - Teachers -- Housing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59937596?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B48&rft.isbn=&rft.btitle=Rural+Teacher+Housing+Act%3A+hearing%2C+March+16%2C+2004+in+Anchorage%2C+Alaska&rft.title=Rural+Teacher+Housing+Act%3A+hearing%2C+March+16%2C+2004+in+Anchorage%2C+Alaska&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Assistive technologies for independent aging: opportunities and challenges: hearing, April 27, 2004 T2 - 108th Cong., 2d sess. Serial no. 108-33 S. hearing 108-523 AN - 59935932; 2004-1001670 AB - Describes potential of state-of-the art devices and services which can improve senior citizens' quality of life and enable them to remain independent at home, current research and development, and challenges of translating new technologies into products that are both affordable and practical. JF - Superintendent of Documents, 2004. iii+211 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+211 PB - Superintendent of Documents KW - Technological innovations -- Social aspects KW - United States -- Medical sector KW - Self-help devices for the disabled -- United States KW - Old age -- United States KW - Quality of life -- United States KW - Research and development -- United States KW - Old age -- Care and treatment KW - Old age -- Home care UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59935932?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B211&rft.isbn=&rft.btitle=Assistive+technologies+for+independent+aging%3A+opportunities+and+challenges%3A+hearing%2C+April+27%2C+2004&rft.title=Assistive+technologies+for+independent+aging%3A+opportunities+and+challenges%3A+hearing%2C+April+27%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Fighting HIV/AIDS in Africa: a progress report: hearing, April 7, 2004 T2 - 108th Cong., 2d sess. S. hearing 108-560 AN - 59933788; 2004-1011460 AB - Discusses goals, how to measure progress, and effective budget spending of US funds. JF - Superintendent of Documents, 2004. iii+68 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+68 PB - Superintendent of Documents KW - Africa -- Health conditions KW - Health planning -- International cooperation KW - HIV positive persons -- Africa KW - United States -- Foreign relations -- Africa KW - Africa -- Foreign relations -- United States KW - United States -- Economic assistance program -- Africa KW - Acquired immune deficiency syndrome -- Africa UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59933788?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B68&rft.isbn=&rft.btitle=Fighting+HIV%2FAIDS+in+Africa%3A+a+progress+report%3A+hearing%2C+April+7%2C+2004&rft.title=Fighting+HIV%2FAIDS+in+Africa%3A+a+progress+report%3A+hearing%2C+April+7%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - U.S. tax shelter industry: the role of accountants, lawyers, and financial professionals: hearings, November 18 and 20, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-473 AN - 59932618; 2004-1007260 AB - Examines ethical standards of legal, accounting, and financial services in designing and marketing abusive and potentially illegal tax shelters to corporations and wealthy individuals. JF - Superintendent of Documents, 2004. 3858 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 3858 PB - Superintendent of Documents KW - Financial services -- United States KW - Accounting -- Ethics KW - Tax evasion -- United States KW - United States -- Service sector KW - Legal ethics -- United States KW - Professional ethics -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59932618?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=U.S.+tax+shelter+industry%3A+the+role+of+accountants%2C+lawyers%2C+and+financial+professionals%3A+hearings%2C+November+18+and+20%2C+2003&rft.title=U.S.+tax+shelter+industry%3A+the+role+of+accountants%2C+lawyers%2C+and+financial+professionals%3A+hearings%2C+November+18+and+20%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), map(s), table(s) N1 - SuppNotes - 4v N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Terrorism financing: origination, organization, and prevention: hearing, July 31, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-245 AN - 59931682; 2004-0400560 AB - Discusses mechanisms used by terrorist groups and efforts of the FBI and Treasury Department to track terrorist assets and secure foreign cooperation; focus on Saudi Arabian involvement in funding of al Qaeda, Hamas, and other organizations. JF - Superintendent of Documents, 2004. iii+194 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+194 PB - Superintendent of Documents KW - Terrorism -- Finance KW - Saudi Arabia -- Foreign relations KW - United States -- Treasury department KW - Counterterrorism -- International cooperation KW - Hamas KW - Al Qaeda KW - United States -- Federal bureau of investigation KW - Terrorism -- Middle East KW - Counterterrorism -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59931682?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B194&rft.isbn=&rft.btitle=Terrorism+financing%3A+origination%2C+organization%2C+and+prevention%3A+hearing%2C+July+31%2C+2003&rft.title=Terrorism+financing%3A+origination%2C+organization%2C+and+prevention%3A+hearing%2C+July+31%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Federal Reserve's first monetary policy report for 2004: hearing, February 12, 2004, on oversight on the monetary policy report to Congress pursuant to the Full Employment and Balanced Growth Act of 1978 T2 - 108th Cong., 2d sess. S. hearing 108-488 AN - 59907071; 2004-1001240 AB - Monetary policy and state of the US economy; includes testimony of Alan Greenspan, chairman of the Federal Reserve System. JF - Superintendent of Documents, 2004. iii+90 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+90 PB - Superintendent of Documents KW - United States -- Monetary policy KW - Federal reserve system KW - United States -- Economic conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59907071?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B90&rft.isbn=&rft.btitle=Federal+Reserve%27s+first+monetary+policy+report+for+2004%3A+hearing%2C+February+12%2C+2004%2C+on+oversight+on+the+monetary+policy+report+to+Congress+pursuant+to+the+Full+Employment+and+Balanced+Growth+Act+of+1978&rft.title=Federal+Reserve%27s+first+monetary+policy+report+for+2004%3A+hearing%2C+February+12%2C+2004%2C+on+oversight+on+the+monetary+policy+report+to+Congress+pursuant+to+the+Full+Employment+and+Balanced+Growth+Act+of+1978&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Spokane tribe of Indians of the Spokane Reservation Grand Coulee Dam Equitable Compensation Settlement Act: hearing, October 2, 2003, on S. 1438 to provide equitable compensation of the Spokane tribe of Indians of the Spokane Reservation in settlement of claims of the tribe concerning the contribution of the tribe to the production of hydropower by the Grand Coulee Dam T2 - 108th Cong., 1st sess. S. hearing 108-375 AN - 59902606; 2004-0601990 JF - Superintendent of Documents, 2004. iii+70 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+70 PB - Superintendent of Documents KW - Hydroelectric power -- United States -- Washington (state) KW - Indians -- Land tenure KW - Dams -- United States -- Washington (state) KW - Compensation (law) -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59902606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B70&rft.isbn=&rft.btitle=Spokane+tribe+of+Indians+of+the+Spokane+Reservation+Grand+Coulee+Dam+Equitable+Compensation+Settlement+Act%3A+hearing%2C+October+2%2C+2003%2C+on+S.+1438+to+provide+equitable+compensation+of+the+Spokane+tribe+of+Indians+of+the+Spokane+Reservation+in+settlement+of+claims+of+the+tribe+concerning+the+contribution+of+the+tribe+to+the+production+of+hydropower+by+the+Grand+Coulee+Dam&rft.title=Spokane+tribe+of+Indians+of+the+Spokane+Reservation+Grand+Coulee+Dam+Equitable+Compensation+Settlement+Act%3A+hearing%2C+October+2%2C+2003%2C+on+S.+1438+to+provide+equitable+compensation+of+the+Spokane+tribe+of+Indians+of+the+Spokane+Reservation+in+settlement+of+claims+of+the+tribe+concerning+the+contribution+of+the+tribe+to+the+production+of+hydropower+by+the+Grand+Coulee+Dam&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Tribal government amendments to the Homeland Security Act of 2002: hearing, July 30, 2003, on S. 578 to amend the Homeland Security Act of 2002 to include Indian tribes among the entities consulted with respect to activities carried out by the Secretary of Homeland Security T2 - 108th Cong., 1st sess. S. hearing 108-312 AN - 59902567; 2004-0601980 JF - Superintendent of Documents, 2004. iii+213 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+213 PB - Superintendent of Documents KW - Tribes and tribal system -- United States KW - Internal security -- United States KW - United States -- Homeland security department KW - United States -- Defenses KW - Counterterrorism -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59902567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B213&rft.isbn=&rft.btitle=Tribal+government+amendments+to+the+Homeland+Security+Act+of+2002%3A+hearing%2C+July+30%2C+2003%2C+on+S.+578+to+amend+the+Homeland+Security+Act+of+2002+to+include+Indian+tribes+among+the+entities+consulted+with+respect+to+activities+carried+out+by+the+Secretary+of+Homeland+Security&rft.title=Tribal+government+amendments+to+the+Homeland+Security+Act+of+2002%3A+hearing%2C+July+30%2C+2003%2C+on+S.+578+to+amend+the+Homeland+Security+Act+of+2002+to+include+Indian+tribes+among+the+entities+consulted+with+respect+to+activities+carried+out+by+the+Secretary+of+Homeland+Security&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), map(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Child Protection and Family Violence Prevention Act: hearing on S. 1601 to amend the Indian Child Protection and Family Violence Prevention Act to provide for the reporting and reduction of child abuse and family violence incidences on Indian reservations, September 24, 2003, Washington, DC T2 - 108th Cong., 1st sess. S. hearing 108-341 AN - 59899150; 2004-0607700 JF - Superintendent of Documents, 2004. iii+110 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+110 PB - Superintendent of Documents KW - Family violence -- United States KW - Indians -- Children -- Legal status, laws, etc. KW - Child abuse -- United States KW - Indians -- Reservations KW - United States -- Social policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59899150?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B110&rft.isbn=&rft.btitle=Child+Protection+and+Family+Violence+Prevention+Act%3A+hearing+on+S.+1601+to+amend+the+Indian+Child+Protection+and+Family+Violence+Prevention+Act+to+provide+for+the+reporting+and+reduction+of+child+abuse+and+family+violence+incidences+on+Indian+reservations%2C+September+24%2C+2003%2C+Washington%2C+DC&rft.title=Child+Protection+and+Family+Violence+Prevention+Act%3A+hearing+on+S.+1601+to+amend+the+Indian+Child+Protection+and+Family+Violence+Prevention+Act+to+provide+for+the+reporting+and+reduction+of+child+abuse+and+family+violence+incidences+on+Indian+reservations%2C+September+24%2C+2003%2C+Washington%2C+DC&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Elder justice and protection: stopping the financial abuse: examining financial abuse and exploitation of the elderly, focusing on issues that elderly consumers face in today's investment marketplace: hearing, October 30, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-382 AN - 59895658; 2004-0508410 AB - Discusses exploitation of vulnerable senior citizens by fraudulent salesmen, scam artists, family, friends, and caregivers, and provisions of the proposed Elder Justice Abuse Act. JF - Superintendent of Documents, 2004. iii+63 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+63 PB - Superintendent of Documents KW - Consumer protection -- United States KW - Old age -- Economic aspects KW - Crime and criminals -- United States KW - United States -- Social conditions KW - Old age -- Crimes against KW - Fraud -- United States KW - Elder abuse -- United States KW - United States -- Law enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59895658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B63&rft.isbn=&rft.btitle=Elder+justice+and+protection%3A+stopping+the+financial+abuse%3A+examining+financial+abuse+and+exploitation+of+the+elderly%2C+focusing+on+issues+that+elderly+consumers+face+in+today%27s+investment+marketplace%3A+hearing%2C+October+30%2C+2003&rft.title=Elder+justice+and+protection%3A+stopping+the+financial+abuse%3A+examining+financial+abuse+and+exploitation+of+the+elderly%2C+focusing+on+issues+that+elderly+consumers+face+in+today%27s+investment+marketplace%3A+hearing%2C+October+30%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - The Congo Basin Forest Partnership: hearing, July 24, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-246 AN - 59894509; 2004-0308740 AB - Discusses how the US government, in cooperation with other governments and nongovernmental organizations (NGOs), can help the Partnership preserve the ecology of this tropical forest, and promote economic development and improve local governance, through natural resource conservation programs. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+49 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+49 PB - Superintendent of Documents KW - Africa -- Economic development KW - Environmental policy -- International cooperation KW - Nature conservation -- Africa KW - Nongovernmental organizations -- Africa KW - United States -- Economic assistance program KW - Forest conservation -- Africa KW - Ecology -- Africa KW - Congo river region -- Environmental conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59894509?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B49&rft.isbn=&rft.btitle=The+Congo+Basin+Forest+Partnership%3A+hearing%2C+July+24%2C+2003&rft.title=The+Congo+Basin+Forest+Partnership%3A+hearing%2C+July+24%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Palestinian education--teaching peace or war? special hearing, October 30, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-290 AN - 59892818; 2004-0400510 AB - Discusses concerns that new Ministry of Education textbooks for grades K-12, while containing fewer stereotypes and less negative terminology than the prior version, fail to provide positive images of Jews and Israel needed for the peace process; US funding of the Palestinian Authority (PA) and Agency for International Development (USAID) programs. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+70 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+70 PB - Superintendent of Documents KW - United States -- International development agency KW - United States -- Foreign relations -- Palestine KW - Palestinian National Authority KW - Curriculum -- Palestine KW - Textbooks -- Palestine KW - Palestine -- Foreign relations -- United States KW - Peace -- Middle East KW - Palestinians -- Education KW - Anti-Semitism -- Middle East UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59892818?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B70&rft.isbn=&rft.btitle=Palestinian+education--teaching+peace+or+war%3F+special+hearing%2C+October+30%2C+2003&rft.title=Palestinian+education--teaching+peace+or+war%3F+special+hearing%2C+October+30%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - American Indian Probate Reform Act: hearing, October 15, 2003 on S. 550 to amend Indian Land Consolidation Act to improve provisions relating to probate of trust and restricted land T2 - 108th Cong., 1st sess. S. hearing 108-379 AN - 59880429; 2004-0600720 JF - Superintendent of Documents, 2004. iii+147 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+147 PB - Superintendent of Documents KW - United States -- Native races -- Legal status, laws, etc. KW - Indians -- Land tenure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59880429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B147&rft.isbn=&rft.btitle=American+Indian+Probate+Reform+Act%3A+hearing%2C+October+15%2C+2003+on+S.+550+to+amend+Indian+Land+Consolidation+Act+to+improve+provisions+relating+to+probate+of+trust+and+restricted+land&rft.title=American+Indian+Probate+Reform+Act%3A+hearing%2C+October+15%2C+2003+on+S.+550+to+amend+Indian+Land+Consolidation+Act+to+improve+provisions+relating+to+probate+of+trust+and+restricted+land&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Supporting military families: the Groton model; hearing, June 16, 2003, on examining how effective the Navy has been in making it easier for military families raising children and to determine what additional changes can be made to further assist military families T2 - 108th Cong., 1st sess. S. hearing 108-306 AN - 59879788; 2004-0602000 JF - Superintendent of Documents, 2004. iii+34 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+34 PB - Superintendent of Documents KW - United States -- Navy KW - Military dependents -- United States KW - Family -- United States KW - Child welfare -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59879788?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B34&rft.isbn=&rft.btitle=Supporting+military+families%3A+the+Groton+model%3B+hearing%2C+June+16%2C+2003%2C+on+examining+how+effective+the+Navy+has+been+in+making+it+easier+for+military+families+raising+children+and+to+determine+what+additional+changes+can+be+made+to+further+assist+military+families&rft.title=Supporting+military+families%3A+the+Groton+model%3B+hearing%2C+June+16%2C+2003%2C+on+examining+how+effective+the+Navy+has+been+in+making+it+easier+for+military+families+raising+children+and+to+determine+what+additional+changes+can+be+made+to+further+assist+military+families&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Lumbee recognition: hearing, Sept. 17, 2003, on S. 420 to provide for the acknowledgment of the Lumbee tribe of North Carolina T2 - 108th Cong., 1st sess. S. hearing 108-336 AN - 59879694; 2004-0600790 JF - Superintendent of Documents, 2004. iii+161 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+161 PB - Superintendent of Documents KW - Indians -- Legal status, laws, etc. KW - Tribes and tribal system -- United States -- North Carolina KW - North Carolina -- Native races -- Legal status, laws, etc. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59879694?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B161&rft.isbn=&rft.btitle=Lumbee+recognition%3A+hearing%2C+Sept.+17%2C+2003%2C+on+S.+420+to+provide+for+the+acknowledgment+of+the+Lumbee+tribe+of+North+Carolina&rft.title=Lumbee+recognition%3A+hearing%2C+Sept.+17%2C+2003%2C+on+S.+420+to+provide+for+the+acknowledgment+of+the+Lumbee+tribe+of+North+Carolina&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), map(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Keeping the lights on: the federal role in managing the nation's electricity; hearings, September 10 and November 20, 2003 T2 - 108th Cong.,1st sess. S. hearing 108-277 AN - 59877981; 2004-0610780 AB - Discusses electric reliability and transmission, prevention of power failures, and the role of federal agencies and offices in context of the Aug. 14, 2003 blackout that effected the Northeast and Midwest of the US, and Ontario, Canada. JF - Superintendent of Documents, 2004. iv+487 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+487 PB - Superintendent of Documents KW - Electric transmission -- United States KW - Electric power -- Power failures KW - Government agencies -- United States KW - United States -- Energy sector KW - United States -- Energy department UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877981?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B487&rft.isbn=&rft.btitle=Keeping+the+lights+on%3A+the+federal+role+in+managing+the+nation%27s+electricity%3B+hearings%2C+September+10+and+November+20%2C+2003&rft.title=Keeping+the+lights+on%3A+the+federal+role+in+managing+the+nation%27s+electricity%3B+hearings%2C+September+10+and+November+20%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - The Middle East Road Map: overcoming obstacles to peace: hearing, October 5, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-316 AN - 59877972; 2004-0607630 AB - US-sponsored Palestinian-Israeli peace plan; discusses issues of settlements and settlement outposts, intifada, security fence, Arafat's influence, and other topics. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+48 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+48 PB - Superintendent of Documents KW - Palestinians KW - United States -- Foreign relations -- Middle East KW - Middle East -- Foreign relations -- United States KW - Israel -- Government and politics KW - Peace -- Middle East KW - Middle East -- Government and politics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877972?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B48&rft.isbn=&rft.btitle=The+Middle+East+Road+Map%3A+overcoming+obstacles+to+peace%3A+hearing%2C+October+5%2C+2003&rft.title=The+Middle+East+Road+Map%3A+overcoming+obstacles+to+peace%3A+hearing%2C+October+5%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - The Worldcom case: looking at bankruptcy and competition issues: hearing, July 22, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-26 S. hearing 108-343 AN - 59877949; 2004-0607990 AB - Includes implications of a reorganized MCI emerging from bankruptcy on competititon in the telecommunications market. JF - Superintendent of Documents, 2004. iii+149 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+149 PB - Superintendent of Documents KW - Telecommunications -- United States KW - Business -- Corrupt practices KW - WorldCom, Inc. KW - Bankruptcy -- United States KW - Competition -- United States KW - MCI communications corporation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B149&rft.isbn=&rft.btitle=The+Worldcom+case%3A+looking+at+bankruptcy+and+competition+issues%3A+hearing%2C+July+22%2C+2003&rft.title=The+Worldcom+case%3A+looking+at+bankruptcy+and+competition+issues%3A+hearing%2C+July+22%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - What is your child reading in school? how standards and textbooks influence education: hearing on examining conflicts taking place over state history standards and history textbooks, focusing on how standards and textbooks influence education, September 24, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-272 AN - 59877926; 2004-0607960 AB - United States. JF - Superintendent of Documents, 2004. iii+77 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+77 PB - Superintendent of Documents KW - History -- Textbooks KW - History -- Study and teaching KW - United States -- Educational policy KW - Education -- Standards KW - Textbooks -- Standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877926?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B77&rft.isbn=&rft.btitle=What+is+your+child+reading+in+school%3F+how+standards+and+textbooks+influence+education%3A+hearing+on+examining+conflicts+taking+place+over+state+history+standards+and+history+textbooks%2C+focusing+on+how+standards+and+textbooks+influence+education%2C+September+24%2C+2003&rft.title=What+is+your+child+reading+in+school%3F+how+standards+and+textbooks+influence+education%3A+hearing+on+examining+conflicts+taking+place+over+state+history+standards+and+history+textbooks%2C+focusing+on+how+standards+and+textbooks+influence+education%2C+September+24%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Clean Air Act: alternative fuels and fuel additives: hearing on provisions of the Clean Air Act to support clean-burning fuel alternatives, March 20, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-300 AN - 59877849; 2004-0607200 AB - Discusses advantages of using alternative and renewable fuels such as ethanol and biodiesel for a viable energy policy; US. JF - Superintendent of Documents, 2004. iii+152 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+152 PB - Superintendent of Documents KW - United States -- Energy policy -- Environmental aspects KW - United States -- Energy policy KW - Renewable energy sources -- Environmental aspects KW - Alcohol as fuel -- Environmental aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877849?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B152&rft.isbn=&rft.btitle=Clean+Air+Act%3A+alternative+fuels+and+fuel+additives%3A+hearing+on+provisions+of+the+Clean+Air+Act+to+support+clean-burning+fuel+alternatives%2C+March+20%2C+2003&rft.title=Clean+Air+Act%3A+alternative+fuels+and+fuel+additives%3A+hearing+on+provisions+of+the+Clean+Air+Act+to+support+clean-burning+fuel+alternatives%2C+March+20%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Federal funding for stem cell research: special hearing, May 22, 2003, Washington, DC T2 - 108th Cong., 1st sess. S. hearing 108-249 AN - 59877820; 2004-0607080 AB - Also available on the Internet. JF - Superintendent of Documents, 2004. iii+92 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+92 PB - Superintendent of Documents KW - United States -- Science policy KW - Stem cell research -- Federal aid UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B92&rft.isbn=&rft.btitle=Federal+funding+for+stem+cell+research%3A+special+hearing%2C+May+22%2C+2003%2C+Washington%2C+DC&rft.title=Federal+funding+for+stem+cell+research%3A+special+hearing%2C+May+22%2C+2003%2C+Washington%2C+DC&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Intergovernmental Panel on Climate Change (IPCC) third assessment report: hearing, May 1, 2001 T2 - 107th Cong., 1st sess. S. hearing 107-1027 AN - 59877806; 2004-0607130 AB - Up-to-date assessment of published and peer-reviewed policy relevant scientific, technical, and socioeconomic literature JF - Superintendent of Documents, 2004. iii+87 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+87 PB - Superintendent of Documents KW - Climate -- International aspects KW - Global warming KW - United States -- Environmental policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877806?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B87&rft.isbn=&rft.btitle=Intergovernmental+Panel+on+Climate+Change+%28IPCC%29+third+assessment+report%3A+hearing%2C+May+1%2C+2001&rft.title=Intergovernmental+Panel+on+Climate+Change+%28IPCC%29+third+assessment+report%3A+hearing%2C+May+1%2C+2001&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), diag(s), map(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Clean Air Act: risks from greenhouse gas emissions: hearing on the economic and environmental risks associated with increasing greenhouse gas emissions, March 13, 2002 T2 - 107th Cong., 2d sess. S. hearing 107-994 AN - 59877789; 2004-0607000 AB - Discusses magnitude of possible injuries or losses that may be caused by global warming. JF - Superintendent of Documents, 2004. iv+209 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+209 PB - Superintendent of Documents KW - Climate -- International aspects KW - Global warming KW - United States -- Environmental policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59877789?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B209&rft.isbn=&rft.btitle=Clean+Air+Act%3A+risks+from+greenhouse+gas+emissions%3A+hearing+on+the+economic+and+environmental+risks+associated+with+increasing+greenhouse+gas+emissions%2C+March+13%2C+2002&rft.title=Clean+Air+Act%3A+risks+from+greenhouse+gas+emissions%3A+hearing+on+the+economic+and+environmental+risks+associated+with+increasing+greenhouse+gas+emissions%2C+March+13%2C+2002&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Indian Money Account Claims Satisfaction Act: hearing, October 29, 2003 on S. 1170 to establish a voluntary alternative claims resolution process to reach a settlement of pending class act action litigation T2 - 108th Cong., 1st sess. S. hearing 108-389 AN - 59875874; 2004-0612160 AB - Discusses bill to establish a voluntary alternative claims resolution process to reach a settlement of pending class act action litigation; in response to complications and large budget for historical accounting of Individual Indian money accounts; US. JF - Superintendent of Documents, 2004. iii+77 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+77 PB - Superintendent of Documents KW - Tribes and tribal system -- United States KW - Indians -- Legal status, laws, etc. KW - Trusts and trustees -- United States KW - United States -- Indian affairs bureau KW - Indians -- Economic conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59875874?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B77&rft.isbn=&rft.btitle=Indian+Money+Account+Claims+Satisfaction+Act%3A+hearing%2C+October+29%2C+2003+on+S.+1170+to+establish+a+voluntary+alternative+claims+resolution+process+to+reach+a+settlement+of+pending+class+act+action+litigation&rft.title=Indian+Money+Account+Claims+Satisfaction+Act%3A+hearing%2C+October+29%2C+2003+on+S.+1170+to+establish+a+voluntary+alternative+claims+resolution+process+to+reach+a+settlement+of+pending+class+act+action+litigation&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Iraq: next steps--how can democratic institutions succeed in Iraq and the Middle East? hearing, September 24, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-282 AN - 59874823; 2004-0400720 AB - Discusses challenges faced by the Coalition Provisional Authority (CPA) and the 25-member Iraqi Interim Governing Council in advancing the constitutional and political processes in view of deep sectarian and ethnic divisions between the formerly dominant Sunnis and the Shiites and Kurds. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+59 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+59 PB - Superintendent of Documents KW - Sunnites -- Iraq KW - Shiites -- Iraq KW - Iraq -- Constitution KW - Coalition Provisional Authority KW - Institution building -- Iraq KW - Legitimacy of governments -- Iraq KW - Democracy -- Middle East KW - Kurds in Iraq KW - Democracy -- Iraq UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59874823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B59&rft.isbn=&rft.btitle=Iraq%3A+next+steps--how+can+democratic+institutions+succeed+in+Iraq+and+the+Middle+East%3F+hearing%2C+September+24%2C+2003&rft.title=Iraq%3A+next+steps--how+can+democratic+institutions+succeed+in+Iraq+and+the+Middle+East%3F+hearing%2C+September+24%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Federal Reserve's second monetary policy report for 2003: hearing, July 16, 2003, on oversight on the monetary policy report to Congress pursuant to the Full Employment and Balanced Growth Act of 1978 T2 - 108th Cong., 1st sess. S. hearing 108-281 AN - 59874334; 2004-0400100 AB - Monetary policy and state of the US economy; includes testimony of Alan Greenspan, chairman of the Federal Reserve System. JF - Superintendent of Documents, 2004. iii+98 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+98 PB - Superintendent of Documents KW - United States -- Monetary policy KW - Federal reserve system KW - United States -- Economic conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59874334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B98&rft.isbn=&rft.btitle=Federal+Reserve%27s+second+monetary+policy+report+for+2003%3A+hearing%2C+July+16%2C+2003%2C+on+oversight+on+the+monetary+policy+report+to+Congress+pursuant+to+the+Full+Employment+and+Balanced+Growth+Act+of+1978&rft.title=Federal+Reserve%27s+second+monetary+policy+report+for+2003%3A+hearing%2C+July+16%2C+2003%2C+on+oversight+on+the+monetary+policy+report+to+Congress+pursuant+to+the+Full+Employment+and+Balanced+Growth+Act+of+1978&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Iraq: next steps--what will an Iraq 5-year plan look like? hearing, September 24, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-276 AN - 59871517; 2004-0400810 AB - Testimony by Administrator of the Coalition Provisional Authority (CPA) L. Paul Bremer on economic costs of reconstruction, the writing of an Iraqi constitution, restoration of sovereignty, development of democratic institutions, security, roles of the US military and international community, and other issues. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+67 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+67 PB - Superintendent of Documents KW - Iraq -- Reconstruction KW - United States -- Armed forces -- Forces in Iraq KW - Iraq -- Constitution KW - Bremer, Lewis Paul, III KW - Internal security -- Iraq KW - Coalition Provisional Authority KW - United States -- Military policy KW - Sovereignty -- Iraq KW - Democracy -- Iraq UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59871517?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B67&rft.isbn=&rft.btitle=Iraq%3A+next+steps--what+will+an+Iraq+5-year+plan+look+like%3F+hearing%2C+September+24%2C+2003&rft.title=Iraq%3A+next+steps--what+will+an+Iraq+5-year+plan+look+like%3F+hearing%2C+September+24%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Iraq: status and prospects for reconstruction--resources: hearing, July 29, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-255 AN - 59871503; 2004-0400670 AB - Discusses the costs of the occupation, concerns regarding the lack of progress in rebuilding the infrastructure and establishing law and order, and need for participation by the international community; includes testimonies by Deputy Secretary of Defense Paul Wolfowitz and U.S. Army Acting Chief of Staff General John M. Keane. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+97 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+97 PB - Superintendent of Documents KW - Iraq -- Reconstruction KW - Military occupation -- Iraq KW - Infrastructure -- Iraq KW - Internal security -- Iraq KW - Wolfowitz, Paul Dundes KW - United States -- Military policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59871503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B97&rft.isbn=&rft.btitle=Iraq%3A+status+and+prospects+for+reconstruction--resources%3A+hearing%2C+July+29%2C+2003&rft.title=Iraq%3A+status+and+prospects+for+reconstruction--resources%3A+hearing%2C+July+29%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Elder justice and protection: stopping the abuse: hearing, August 19, 2003, on examining the serious problem of elder abuse, determining ways of prevention and ensuring that crimes against the elderly are reported and those responsible are prosecuted T2 - 108th Cong., 1st sess. S. hearing 108-226 AN - 59868868; 2004-0305620 AB - Discusses instances of mistreatment of seniors, focusing on conditions in nursing homes, and the proposed Elderly Justice Act, which would coordinate federal, state, and local elder abuse prevention efforts, establish programs to aid victims, and facilitate criminal background checks of elder care employees; US. JF - Superintendent of Documents, 2004. iii+38 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+38 PB - Superintendent of Documents KW - United States -- Social conditions KW - Nursing homes -- United States KW - Old age -- Crimes against KW - United States -- Social policy KW - Elder abuse -- United States KW - United States -- Law enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59868868?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B38&rft.isbn=&rft.btitle=Elder+justice+and+protection%3A+stopping+the+abuse%3A+hearing%2C+August+19%2C+2003%2C+on+examining+the+serious+problem+of+elder+abuse%2C+determining+ways+of+prevention+and+ensuring+that+crimes+against+the+elderly+are+reported+and+those+responsible+are+prosecuted&rft.title=Elder+justice+and+protection%3A+stopping+the+abuse%3A+hearing%2C+August+19%2C+2003%2C+on+examining+the+serious+problem+of+elder+abuse%2C+determining+ways+of+prevention+and+ensuring+that+crimes+against+the+elderly+are+reported+and+those+responsible+are+prosecuted&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Shattering the silence: confronting the perils of family elder abuse: hearing, October 20, 2003 T2 - 108th Cong, 1st sess. Serial no. 108-25 S. hearing 108-288 AN - 59867347; 2004-0508430 AB - Describes incidents of physical abuse, neglect, and financial exploitation and the proposed Elder Justice Act. JF - Superintendent of Documents, 2004. iii+53 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+53 PB - Superintendent of Documents KW - Old age -- Economic aspects KW - Crime and criminals -- United States KW - Family violence -- United States KW - United States -- Social conditions KW - Old age -- Crimes against KW - Elder abuse -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59867347?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B53&rft.isbn=&rft.btitle=Shattering+the+silence%3A+confronting+the+perils+of+family+elder+abuse%3A+hearing%2C+October+20%2C+2003&rft.title=Shattering+the+silence%3A+confronting+the+perils+of+family+elder+abuse%3A+hearing%2C+October+20%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Ageism in health care: are our nation's seniors receiving proper oral health care? hearing, September 22, 2003 T2 - 108th Cong., 1st sess. Serial no. 108-22 AN - 59866207; 2004-0305570 AB - Discusses public health implications of seniors' lack of access to dental services and inability to afford out-of-pocket expenses; proposes measures including expanded Medicare and Medicaid coverage and a geriatic component as part of dental education programs; US. JF - Superintendent of Documents, 2004. iii+153 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+153 PB - Superintendent of Documents KW - Medicaid program -- United States KW - United States -- Medical sector KW - Dental service -- United States KW - Old age -- Dental care KW - Old age -- Health KW - Public health -- United States KW - Dental education -- United States KW - Medicare -- United States KW - Age discrimination -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59866207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B153&rft.isbn=&rft.btitle=Ageism+in+health+care%3A+are+our+nation%27s+seniors+receiving+proper+oral+health+care%3F+hearing%2C+September+22%2C+2003&rft.title=Ageism+in+health+care%3A+are+our+nation%27s+seniors+receiving+proper+oral+health+care%3F+hearing%2C+September+22%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), il(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Alien smuggling/human trafficking: sending a meaningful message of deterrence; hearing, July 25, 2003 T2 - 108th Cong., 1st sess. Serial no. J-108-30 S. hearing 108-315 AN - 59865516; 2004-0505630 AB - Examines efforts and capacity of law enforcement to combat smuggling crimes; US. JF - Superintendent of Documents, 2004. iii+90 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+90 PB - Superintendent of Documents KW - Crime and criminals -- International aspects KW - Human smuggling -- United States KW - Aliens, Illegal -- United States KW - United States -- Law enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59865516?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B90&rft.isbn=&rft.btitle=Alien+smuggling%2Fhuman+trafficking%3A+sending+a+meaningful+message+of+deterrence%3B+hearing%2C+July+25%2C+2003&rft.title=Alien+smuggling%2Fhuman+trafficking%3A+sending+a+meaningful+message+of+deterrence%3B+hearing%2C+July+25%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - SARS: is Minnesota prepared? hearing, October 8, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-367 AN - 59865457; 2004-0505210 AB - Focus on how state government officials are preparing for a possible outbreak of Severe Acute Respiratory Syndrome during the flu season. JF - Superintendent of Documents, 2004. iii+63 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+63 PB - Superintendent of Documents KW - Public health -- United States -- Minnesota KW - Minnesota -- Health policy KW - State government -- United States -- Minnesota KW - Severe acute respiratory syndrome -- Prevention KW - Health planning -- United States -- Minnesota UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59865457?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B63&rft.isbn=&rft.btitle=SARS%3A+is+Minnesota+prepared%3F+hearing%2C+October+8%2C+2003&rft.title=SARS%3A+is+Minnesota+prepared%3F+hearing%2C+October+8%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Oversight of GAO: what lies ahead for Congress' watchdog? hearing, September 16, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-262 AN - 59864945; 2004-0400520 AB - Discusses the prospects for the US Government Accounting Office. JF - Superintendent of Documents, 2004. iii+143 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+143 PB - Superintendent of Documents KW - Government agencies -- Evaluation KW - United States -- General accounting office UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59864945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B143&rft.isbn=&rft.btitle=Oversight+of+GAO%3A+what+lies+ahead+for+Congress%27+watchdog%3F+hearing%2C+September+16%2C+2003&rft.title=Oversight+of+GAO%3A+what+lies+ahead+for+Congress%27+watchdog%3F+hearing%2C+September+16%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - From Reform to Repression: The Post-New Order's Shifting Security Policies in Aceh AN - 59726973; 200613525 AB - Examines efforts to reform the security sector in Indonesia & deal with the conflict in Aceh since the end of General Suharto's authoritarian New Order regime. The impact of regime change on state capacity & center-periphery relations is discussed to contend that regime change in Indonesia decreased the state's capacity to either govern effectively within its borders or coordinate its policies with state capacity in Aceh. The Aceh conflict gave "hard line" state actors an opportunity to again play an important role in political decision-making. An overview of the armed separatist struggle of the Free Aceh Movement highlights the impact of various policies, especially those related to counterinsurgency, on Acehnese compliance/non-compliance with Indonesian state authority. Attention is given to the historical context that gave rise to the conflict; post-Suharto attempts to both restore Acehnese faith in Indonesian rule & reform the security sector; & the 2001 return to the New Order regime's repressive approach to Aceh. A postscript notes there was a change in this approach following the disastrous 2004 tsunami. Future prospects are discussed. J. Lindroth JF - RIMA: Review of Indonesian and Malaysian Affairs AU - Miller, Michelle Ann AD - Charles Darwin U michelle.miller@cdu.edu.au Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 129 EP - 161 PB - RIMA, GPO Box 1820, Canberra ACT 2601 Australia VL - 38 IS - 2 SN - 0815-7251, 0815-7251 KW - Ideological Struggle KW - Indonesia KW - Counterinsurgency KW - Security Policy KW - Decision Making KW - Conflict KW - Political Change KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59726973?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.atitle=From+Reform+to+Repression%3A+The+Post-New+Order%27s+Shifting+Security+Policies+in+Aceh&rft.au=Miller%2C+Michelle+Ann&rft.aulast=Miller&rft.aufirst=Michelle&rft.date=2004-01-01&rft.volume=38&rft.issue=2&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.issn=08157251&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Indonesia; Political Change; Security Policy; Conflict; Decision Making; Counterinsurgency; Ideological Struggle ER - TY - JOUR T1 - "A Fair Go All Round": Workplace Relations in the Twenty-First Century Kingsley Laffer Memorial Lecture 2004 AN - 59720810; 200616562 AB - The text of the Kingsley Laffer Memorial Lecture of 2004 presents the argument that industrial relations should not be re-regulated in the name of fairness & that a return to more centralized approaches is not the best option. The uniquely Australian "a fair go all round" approach to workplace relations taken by the Australian Industry (AI) group emphasizes the creation of a policy agenda that increases opportunities & access to them. Workplace institutions must deal with the forces of globalization & demography, as well as changes in the nature of households & the role of the state. It is argued that the challenges of globalization & demography require a more decentralized, enterprise-based approach focused on high productivity & flexible work practices/places. The need to manage interactions between safety net considerations & the larger social safe net of income support & service provision is discussed. It is concluded that the concept of fairness goes beyond increasing material living standards to include building opportunity & coming to terms with increasing diversity. Figures. J. Lindroth JF - RIMA: Review of Indonesian and Malaysian Affairs AU - Ridout, Heather AD - Australian Industry Group Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 226 EP - 241 PB - RIMA, GPO Box 1820, Canberra ACT 2601 Australia VL - 38 IS - 2 SN - 0815-7251, 0815-7251 KW - Industrialization KW - Labor Relations KW - Indonesia KW - Modernization KW - article KW - 9221: politics and society; politics and society UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59720810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.atitle=%22A+Fair+Go+All+Round%22%3A+Workplace+Relations+in+the+Twenty-First+Century+Kingsley+Laffer+Memorial+Lecture+2004&rft.au=Ridout%2C+Heather&rft.aulast=Ridout&rft.aufirst=Heather&rft.date=2004-01-01&rft.volume=38&rft.issue=2&rft.spage=226&rft.isbn=&rft.btitle=&rft.title=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.issn=08157251&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Labor Relations; Indonesia; Industrialization; Modernization ER - TY - JOUR T1 - The 'People in between': Indonesia and the Failed Asylum Seekers to Australia AN - 59718047; 200613458 AB - Examines the situation of refugees who were denied asylum in Australia & are in Indonesia waiting for a decision by the Office of the UN High Commissioner for Refugees (UNHCR). Information is based on anthropological fieldwork carried out in October 2003 on the island of Lombok which included interviews with refugees from Vietnam, Afghanistan, Iran & Iraq, as well as provincial police, & officials from UNHCR & the International Organization of Migration. Many of the refugees interviewed had been living in Lombok for almost three years. The interviews revealed interethnic & religious conflicts among the asylum seekers, as well as social tensions between the migrants & members of the local population. The refugees overwhelmingly felt that returning to their homes is not an option. Although they have been on the move for many months or years, they continued to express hope in spite of their failure to be granted asylum in Australia. The issue of forced migration as a phenomenon is discussed. Excerpts from the interviews are included. References. J. Lindroth JF - RIMA: Review of Indonesian and Malaysian Affairs AU - Hunter, Cynthia AD - U Sydney cynthia.hunter@arts.usyd.edu.au Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 101 EP - 127 PB - RIMA, GPO Box 1820, Canberra ACT 2601 Australia VL - 38 IS - 2 SN - 0815-7251, 0815-7251 KW - Cultural Conflict KW - Ethnic Relations KW - Indonesia KW - Australia KW - Intercultural Communication KW - Refugees KW - Asylum KW - article KW - 9067: international relations; refugees/immigration UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59718047?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.atitle=The+%27People+in+between%27%3A+Indonesia+and+the+Failed+Asylum+Seekers+to+Australia&rft.au=Hunter%2C+Cynthia&rft.aulast=Hunter&rft.aufirst=Cynthia&rft.date=2004-01-01&rft.volume=38&rft.issue=2&rft.spage=101&rft.isbn=&rft.btitle=&rft.title=RIMA%3A+Review+of+Indonesian+and+Malaysian+Affairs&rft.issn=08157251&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 19 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Indonesia; Australia; Refugees; Asylum; Ethnic Relations; Intercultural Communication; Cultural Conflict ER - TY - JOUR T1 - Considering E-Government from the U.S. Federal Perspective: An Evolving Concept, a Developing Practice AN - 59686607; 200601780 AB - Regardless of how e-government may be understood, a reasoned discussion of its meaning or definition serves a very important function. As e-government becomes an integral part of the execution of governmental responsibilities throughout the U.S. federalist system, a common understanding of e-government provides the foundation for future policy analysis & debate that will inevitably follow. In the E-Government Act of 2003, Congress has provided a definition of e-government owing much to many years of information technology development & application, as well as related policy discussions & creation, & includes some common themes that capture the evolutionary nature of e-government. However, while detailed, this statutory definition belies its contextual depth as reflected in practice. Because e-government exists outside of statute, competing definitions result, reflecting the contextual complexity & fluid nature of e-government, & suggesting it may be appropriate to accept a family of definitions rather than select one to the exclusion of another. What these definitions should share in common, however, is a sense that objectives need to drive our technology choices rather than allowing our technology choices to determine our objectives. 11 References. Adapted from the source document. COPIES ARE AVAILABLE FROM: HAWORTH DOCUMENT DELIVERY CENTER, The Haworth Press, Inc., 10 Alice Street, Binghamton, NY 13904-1580 JF - Journal of E-Government AU - Seifert, Jeffrey W AU - Relyea, Harold C AD - Resources/Science/Industry Division, Congressional Research Service, Washington, DC jseifert@crs.loc.gov Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 7 EP - 15 VL - 1 IS - 1 SN - 1542-4049, 1542-4049 KW - e-government KW - E-Government Act, national security, federal, evolutionary concept, digital government, homeland security, enterprise architecture KW - Information Technology KW - United States of America KW - Federal Government KW - article KW - 9181: politics and communication; politics and communication KW - 9263: public policy/administration; public administration/bureaucracy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59686607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+E-Government&rft.atitle=Considering+E-Government+from+the+U.S.+Federal+Perspective%3A+An+Evolving+Concept%2C+a+Developing+Practice&rft.au=Seifert%2C+Jeffrey+W%3BRelyea%2C+Harold+C&rft.aulast=Seifert&rft.aufirst=Jeffrey&rft.date=2004-01-01&rft.volume=1&rft.issue=1&rft.spage=7&rft.isbn=&rft.btitle=&rft.title=Journal+of+E-Government&rft.issn=15424049&rft_id=info:doi/10.1300%2FJ399v01n01_02 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 11 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Federal Government; Information Technology; United States of America DO - http://dx.doi.org/10.1300/J399v01n01_02 ER - TY - BOOK T1 - Enron: Joint Committee on Taxation investigative report on compensation-related issues: hearing, April 8, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-407 AN - 58876723; 2004-0704480 AB - Examines executive and deferred compensation at the now-bankrupt Houston, Texas energy corporation. JF - Superintendent of Documents, 2004. iii+152 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+152 PB - Superintendent of Documents KW - Houston, Texas -- Business enterprises KW - Bankruptcy -- United States -- Texas KW - United States -- Congress -- Joint committee on taxation KW - Wages and salaries -- Executives KW - Enron corporation KW - Executives -- Benefits UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58876723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B152&rft.isbn=&rft.btitle=Enron%3A+Joint+Committee+on+Taxation+investigative+report+on+compensation-related+issues%3A+hearing%2C+April+8%2C+2003&rft.title=Enron%3A+Joint+Committee+on+Taxation+investigative+report+on+compensation-related+issues%3A+hearing%2C+April+8%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Implementation of smallpox vaccination plan: special hearing, January 29, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-221 AN - 58876452; 2004-0702590 AB - Discusses bioterrorism preparedness, focusing on cost, compensation, and safety related to smallpox and other biological weapons; US. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+65 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+65 PB - Superintendent of Documents KW - Vaccination and vaccines -- United States KW - United States -- Medical sector KW - Smallpox -- Prevention KW - Bioterrorism -- United States KW - Biological weapons -- Defenses KW - Disasters -- Emergency preparedness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58876452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B65&rft.isbn=&rft.btitle=Implementation+of+smallpox+vaccination+plan%3A+special+hearing%2C+January+29%2C+2003&rft.title=Implementation+of+smallpox+vaccination+plan%3A+special+hearing%2C+January+29%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Seaport security, law enforcement coordination, and vessel piloting: field hearing, January 10, 2002 T2 - 107th Cong., 2d sess. S. hearing 107-1044 AN - 58875864; 2004-0702550 AB - Discusses proposed legislation and security measures to increase internal security in US ports in response to Sept. 11, 2001 terrorist attacks. Addresses cargo, imports, cruise ships and other maritime transportation; training and financial aspects for local ports. JF - Superintendent of Documents, 2004. iii+55 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+55 PB - Superintendent of Documents KW - Internal security -- United States KW - Ports -- Security measures KW - Maritime industry -- Regulation KW - Shipping -- Security measures KW - United States -- Transportation sector KW - Maritime industry -- Security measures KW - United States -- Defenses KW - Terrorism -- International aspects KW - Counterterrorism -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58875864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B55&rft.isbn=&rft.btitle=Seaport+security%2C+law+enforcement+coordination%2C+and+vessel+piloting%3A+field+hearing%2C+January+10%2C+2002&rft.title=Seaport+security%2C+law+enforcement+coordination%2C+and+vessel+piloting%3A+field+hearing%2C+January+10%2C+2002&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Indian tribal detention facilities: hearing, June 23, 2004 on oversight hearing on issues and problems related to the conditions in Indian Tribal Detention Facilities T2 - 108th Congress, 2d session Senate hearing 108-628 AN - 58870616; 2005-0103160 AB - Discusses issues and problems related to conditions in reservation detention facilities, including abuse, neglect, inhumane conditions, and overcrowding; some focus on juvenile justice; US. JF - Superintendent of Documents, 2004. iii+326 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+326 PB - Superintendent of Documents KW - United States -- Native races -- Legal status, laws, etc. KW - Detention of persons -- United States KW - Indians -- Reservations KW - Prisoners -- United States KW - Tribes and tribal system -- Legal aspects KW - Juvenile justice -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58870616?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B326&rft.isbn=&rft.btitle=Indian+tribal+detention+facilities%3A+hearing%2C+June+23%2C+2004+on+oversight+hearing+on+issues+and+problems+related+to+the+conditions+in+Indian+Tribal+Detention+Facilities&rft.title=Indian+tribal+detention+facilities%3A+hearing%2C+June+23%2C+2004+on+oversight+hearing+on+issues+and+problems+related+to+the+conditions+in+Indian+Tribal+Detention+Facilities&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Nursing home quality revisited: the good, the bad, and the ugly: hearing, July 17, 2003 T2 - 108th Cong., 1st sess. S. hearing 108-325 AN - 58869287; 2004-0702690 AB - Discusses incidents of abuse and substandard care, General Accounting Office (GAO) data on institutional deficiencies, regulatory activities by the Department of Health and Human Services (HHS) Inspector General, and evaluations and ratings by HHS' Centers for Medicare and Medicaid Services (CMS); recommendations. JF - Superintendent of Documents, 2004. iv+627 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+627 PB - Superintendent of Documents KW - Nursing homes -- United States -- Statistics KW - United States -- Health and human services department KW - Nursing homes -- Regulation KW - Elder care -- United States KW - Old age -- Care and treatment KW - Elder abuse -- United States KW - Nursing homes -- Rating UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58869287?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B627&rft.isbn=&rft.btitle=Nursing+home+quality+revisited%3A+the+good%2C+the+bad%2C+and+the+ugly%3A+hearing%2C+July+17%2C+2003&rft.title=Nursing+home+quality+revisited%3A+the+good%2C+the+bad%2C+and+the+ugly%3A+hearing%2C+July+17%2C+2003&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), il(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - To examine the current situation regarding the discovery of a case of bovine spongiform encephalopathy in a dairy cow in Washington State as it relates to food safety, livestock marketing and international trade: hearing, January 27, 2004 T2 - 108th Congress, 2d session Senate hearing 108-451 AN - 58868186; 2005-0203860 AB - Evaluates US Department of Agriculture (USDA) response and testing procedures, and concerns regarding the spread of BSE within the livestock industry and its potential impact on the food supply and beef exports. Also available on the Internet. JF - Superintendent of Documents, 2004. iv+185 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+185 PB - Superintendent of Documents KW - Food supply -- United States KW - Dairy industry -- United States -- Washington (state) KW - Livestock industry -- Export-import trade KW - Mad cow disease -- Prevention KW - United States -- Agriculture department KW - Livestock diseases -- United States KW - Food safety -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58868186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B185&rft.isbn=&rft.btitle=To+examine+the+current+situation+regarding+the+discovery+of+a+case+of+bovine+spongiform+encephalopathy+in+a+dairy+cow+in+Washington+State+as+it+relates+to+food+safety%2C+livestock+marketing+and+international+trade%3A+hearing%2C+January+27%2C+2004&rft.title=To+examine+the+current+situation+regarding+the+discovery+of+a+case+of+bovine+spongiform+encephalopathy+in+a+dairy+cow+in+Washington+State+as+it+relates+to+food+safety%2C+livestock+marketing+and+international+trade%3A+hearing%2C+January+27%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Benefits of a healthy marriage: hearing, May 5, 2004 T2 - 108th Congress, 2d session Senate hearing 108-595 AN - 58867777; 2005-0100740 AB - Discusses social and economic aspects of opposite-sex marriage, especially for low-income individuals, and government policies designed to promote marriage. JF - Superintendent of Documents, 2004. iv+248 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+248 PB - Superintendent of Documents KW - Family life -- Social aspects KW - Marriage -- United States KW - Poor -- Social aspects KW - United States -- Social policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58867777?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B248&rft.isbn=&rft.btitle=Benefits+of+a+healthy+marriage%3A+hearing%2C+May+5%2C+2004&rft.title=Benefits+of+a+healthy+marriage%3A+hearing%2C+May+5%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Suicide prevention and youth: saving lives: hearing on examining certain measures to help prevent suicide among children and adolescents, March 2, 2004 T2 - 108th Congress, 2d sess. Senate hearing 108-489 AN - 58867659; 2005-0100920 AB - Discusses extent of the problem, risk factors, existing programs offering mental health screening and counseling, and proposed legislation to provide grants to organizations to implement early intervention and prevention strategies in schools, juvenile justice facilities, substance abuse programs, and other support entities on a state-wide basis. JF - Superintendent of Documents, 2004. iii+93 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+93 PB - Superintendent of Documents KW - Children -- Mental health KW - Suicide -- Prevention KW - Mental health -- United States KW - United States -- Social conditions KW - Youth -- Mental health KW - Mental health services -- United States KW - United States -- Health policy KW - Suicide -- Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58867659?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B93&rft.isbn=&rft.btitle=Suicide+prevention+and+youth%3A+saving+lives%3A+hearing+on+examining+certain+measures+to+help+prevent+suicide+among+children+and+adolescents%2C+March+2%2C+2004&rft.title=Suicide+prevention+and+youth%3A+saving+lives%3A+hearing+on+examining+certain+measures+to+help+prevent+suicide+among+children+and+adolescents%2C+March+2%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Anti-Semitism in Europe: hearing, April 8, 2004 T2 - 108th Congress, 2d session Senate hearing 108-586 AN - 58867509; 2005-0100840 AB - Discusses extent and manifestations of anti-Jewish prejudice in the 55 Organization for Security and Cooperation in Europe (OSCE) member states, government response, and progress made toward development of programs to counteract anti-Semitism by promoting tolerance; in light of the upcoming OSCE Berlin conference on anti-Semitism. Also available on the Internet. JF - Superintendent of Documents, 2004. iii+95 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+95 PB - Superintendent of Documents KW - Jews -- Public opinion KW - Anti-Semitism -- Europe KW - Toleration -- Europe KW - Organization for security and cooperation in Europe KW - Europe -- Government and politics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58867509?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B95&rft.isbn=&rft.btitle=Anti-Semitism+in+Europe%3A+hearing%2C+April+8%2C+2004&rft.title=Anti-Semitism+in+Europe%3A+hearing%2C+April+8%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Saving lives: the deadly intersection of AIDS and hunger: hearing, May 11, 2004 T2 - 108th Congress, 2d session Senate hearing 108-616 AN - 58867476; 2005-0100690 AB - Discusses connections between HIV/AIDS and global hunger issues, food security and international humanitarian aid; sub-Saharan Africa, chiefly. JF - Superintendent of Documents, 2004. iii+99 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+99 PB - Superintendent of Documents KW - Africa -- Health conditions KW - Hunger -- International aspects KW - Food supply -- International aspects KW - Acquired immune deficiency syndrome -- International aspects KW - International relief UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58867476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B99&rft.isbn=&rft.btitle=Saving+lives%3A+the+deadly+intersection+of+AIDS+and+hunger%3A+hearing%2C+May+11%2C+2004&rft.title=Saving+lives%3A+the+deadly+intersection+of+AIDS+and+hunger%3A+hearing%2C+May+11%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Transition Assistance Program and the Disabled Transition Assistance Program: hearing, July 18, 2002 T2 - 108th Congress, 2d session Senate hearing 108-451 AN - 58863753; 2005-0203920 AB - Evaluates services provided to veterans and disabled veterans by the Departments of Defense, Veterans Affairs, and Labor, and by the branches of the military to enable them to adjust to civilian life upon discharge and obtain long-term employment in light of changes in the programs contained in the Veterans Benefit Expansion Act of 2001. JF - Superintendent of Documents, 2004. iv+139 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+139 PB - Superintendent of Documents KW - United States -- Armed forces -- Legislation KW - United States -- Veterans affairs department KW - United States -- Labor department KW - Veterans, Disabled -- Benefits KW - Veterans -- Benefits KW - Employment -- Veterans KW - United States -- Defense department KW - Employment -- Veterans, Disabled UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58863753?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B139&rft.isbn=&rft.btitle=Transition+Assistance+Program+and+the+Disabled+Transition+Assistance+Program%3A+hearing%2C+July+18%2C+2002&rft.title=Transition+Assistance+Program+and+the+Disabled+Transition+Assistance+Program%3A+hearing%2C+July+18%2C+2002&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Native American Programs Act: hearing, June 8, 2004 on S. 2436 to reauthorize the Native American Programs Act of 1974 T2 - 108th Congress, 2d session Senate hearing 108-594 AN - 58862308; 2005-0100250 AB - The Act of 1974 provides Administration for Native Americans funding for social and economic development initiatives, environmental programs, and preservation of Native languages. JF - Superintendent of Documents, 2004. iii+21 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+21 PB - Superintendent of Documents KW - Culture KW - United States -- Economic development KW - Sustainable development -- United States KW - Languages -- Social aspects KW - Community development -- United States KW - Indians -- Languages KW - United States -- Native races KW - Indians -- Economic conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58862308?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B21&rft.isbn=&rft.btitle=Native+American+Programs+Act%3A+hearing%2C+June+8%2C+2004+on+S.+2436+to+reauthorize+the+Native+American+Programs+Act+of+1974&rft.title=Native+American+Programs+Act%3A+hearing%2C+June+8%2C+2004+on+S.+2436+to+reauthorize+the+Native+American+Programs+Act+of+1974&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Tribal Parity Act: hearing, June 15, 2004 on S. 1530 to provide compensation to the Lower Brule and Crow Creek Sioux Tribes of South Dakota for damage to tribal and land caused by Pick-Sloan projects along the Missouri River T2 - 108th Congress, 2d session Senate hearing 108-620 AN - 58861903; 2005-0100390 AB - Discusses the provision of compensation to the Lower Brule and Crow Creek Sioux Tribes of South Dakota for damage to tribal land caused by Pick-Sloan projects constructing dams along the Missouri River. JF - Superintendent of Documents, 2004. iii+114 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+114 PB - Superintendent of Documents KW - Indians -- Legal status, laws, etc. KW - South Dakota -- Native races KW - Missouri river KW - Dams -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58861903?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B114&rft.isbn=&rft.btitle=Tribal+Parity+Act%3A+hearing%2C+June+15%2C+2004+on+S.+1530+to+provide+compensation+to+the+Lower+Brule+and+Crow+Creek+Sioux+Tribes+of+South+Dakota+for+damage+to+tribal+and+land+caused+by+Pick-Sloan+projects+along+the+Missouri+River&rft.title=Tribal+Parity+Act%3A+hearing%2C+June+15%2C+2004+on+S.+1530+to+provide+compensation+to+the+Lower+Brule+and+Crow+Creek+Sioux+Tribes+of+South+Dakota+for+damage+to+tribal+and+land+caused+by+Pick-Sloan+projects+along+the+Missouri+River&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Indian Gaming Regulatory Act amendments: hearing, March 24, 2004 on S. 1529 to amend the Indian Gaming Regulatory Act to include provisions relating to the payment and administration of gaming fees T2 - 108th Congress, 2d session Senate hearing 108-475 AN - 58860841; 2005-0100120 AB - Also includes provisions relating to the National Indian Gaming Commission. JF - Superintendent of Documents, 2004. iii+126 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+126 PB - Superintendent of Documents KW - United States -- Native races -- Legal status, laws, etc. KW - Indians -- Legal status, laws, etc. KW - Gambling -- Regulation KW - Intergovernmental relations -- United States KW - Casinos -- Regulation KW - Tribes and tribal system -- Economic aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58860841?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B126&rft.isbn=&rft.btitle=Indian+Gaming+Regulatory+Act+amendments%3A+hearing%2C+March+24%2C+2004+on+S.+1529+to+amend+the+Indian+Gaming+Regulatory+Act+to+include+provisions+relating+to+the+payment+and+administration+of+gaming+fees&rft.title=Indian+Gaming+Regulatory+Act+amendments%3A+hearing%2C+March+24%2C+2004+on+S.+1529+to+amend+the+Indian+Gaming+Regulatory+Act+to+include+provisions+relating+to+the+payment+and+administration+of+gaming+fees&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Iraq transition: civil war or civil society? hearing, April 20-21, 2004 T2 - 108th Congress, 2d session Senate hearing 108-578, pts. 1-2 AN - 58858658; 2005-0100910 AB - Discusses transfer of sovereignty to an interim Iraqi government, scheduled for June 30, under proposed plan of UN Representative Lakhdar Brahimi, relationship of US armed forces and the UN to the new government, the Jan. 2005 and Dec. 2005 elections, John Negroponte's appointment as US ambassador, the growing insurgency, and security issues. Also available on the Internet. JF - Superintendent of Documents, 2004. Y1 - 2004///0, PY - 2004 DA - 0, 2004 PB - Superintendent of Documents KW - Military occupation -- Iraq KW - United States -- Armed forces -- Forces in Iraq KW - Insurgency -- Iraq KW - Internal security -- Iraq KW - Negroponte, John Dimitri KW - Iraq -- Government and politics KW - Brahimi, Lakhdar KW - Sovereignty -- Iraq KW - United Nations -- Iraq UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58858658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Iraq+transition%3A+civil+war+or+civil+society%3F+hearing%2C+April+20-21%2C+2004&rft.title=Iraq+transition%3A+civil+war+or+civil+society%3F+hearing%2C+April+20-21%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - SuppNotes - 2pts N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Crime without criminals? seniors, dementia, and the aftermath: hearing, March 22, 2004 T2 - 108th Cong., 2d sess. Serial no. 108-31 S. hearing 108-476 AN - 58851871; 2004-0810650 AB - Discusses violent crimes by elderly persons with dementia, inadequate care and treatment within the health care system, law enforcement and judicial response, and the need for improved mental health services; some focus on Ivan Gotham, a Florida senior with dementia released from involuntary confinement, shot to death after killing a sheriff's deputy. JF - Superintendent of Documents, 2004. iii+141 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+141 PB - Superintendent of Documents KW - Mentally ill -- Commitment and detention KW - United States -- Medical sector KW - Crime and criminals -- United States KW - Mentally ill -- Care and treatment KW - Dementia -- Care and treatment KW - Mental health services -- United States KW - Florida -- Medical sector KW - Old age -- Mental health KW - United States -- Law enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58851871?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B141&rft.isbn=&rft.btitle=Crime+without+criminals%3F+seniors%2C+dementia%2C+and+the+aftermath%3A+hearing%2C+March+22%2C+2004&rft.title=Crime+without+criminals%3F+seniors%2C+dementia%2C+and+the+aftermath%3A+hearing%2C+March+22%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Tribal telecommunications issues: joint hearing, May 14, 2002, before the Committee on Commerce, Science, and Transportation and the Committee on Indian Affairs, United States Senate T2 - 107th Cong., 2d sess. S. hearing 107-1024 AN - 58851664; 2004-0811450 AB - Discusses barriers and issues related to telecommunication services and infrastructure in Indian Country; rural service, economic, legislative, and technical barriers, and potential for economic development; US. JF - Superintendent of Documents, 2004. iii+89 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+89 PB - Superintendent of Documents KW - Technological innovations -- Social aspects KW - Information technology -- United States KW - Rural development -- Information processing systems KW - Telecommunications -- United States KW - United States -- Communications sector KW - Indians -- Social aspects KW - United States -- Technology policy KW - Indians -- Economic conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58851664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B89&rft.isbn=&rft.btitle=Tribal+telecommunications+issues%3A+joint+hearing%2C+May+14%2C+2002%2C+before+the+Committee+on+Commerce%2C+Science%2C+and+Transportation+and+the+Committee+on+Indian+Affairs%2C+United+States+Senate&rft.title=Tribal+telecommunications+issues%3A+joint+hearing%2C+May+14%2C+2002%2C+before+the+Committee+on+Commerce%2C+Science%2C+and+Transportation+and+the+Committee+on+Indian+Affairs%2C+United+States+Senate&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Mad cow disease: are our precautions adequate?: hearing, April 4, 2001 T2 - 108th Cong., 1st sess. S. hearing 107-1060 AN - 58850812; 2004-0810430 AB - Overview of bovine spongiform encephalopathy (BSE), government efforts to prevent the infection in the US, import prohibitions and food safety, and consumer risk. JF - Superintendent of Documents, 2004. iii+100 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iii+100 PB - Superintendent of Documents KW - Public health -- United States KW - Livestock industry -- Export-import trade KW - Mad cow disease -- Prevention KW - Consumers -- United States KW - Communicable diseases in animals KW - United States -- Agricultural policy KW - Livestock diseases -- United States KW - Food safety -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58850812?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iii%2B100&rft.isbn=&rft.btitle=Mad+cow+disease%3A+are+our+precautions+adequate%3F%3A+hearing%2C+April+4%2C+2001&rft.title=Mad+cow+disease%3A+are+our+precautions+adequate%3F%3A+hearing%2C+April+4%2C+2001&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - bibl(s), chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Preserving a strong United States Postal Service: workforce issues: hearings, February 4 and 24, 2004 T2 - 108th Cong., 2d sess. S. hearing 108-439 AN - 58848482; 2004-0809380 AB - Examines USPS reforms recommended by the Presidential Commission on the Postal Service, including labor restructuring in light of declining mail volume due to use of the Internet. JF - Superintendent of Documents, 2004. iv+361 pp. Y1 - 2004///0, PY - 2004 DA - 0, 2004 EP - iv+361 PB - Superintendent of Documents KW - Government employees -- United States KW - United States -- Postal service KW - Mail handling -- United States KW - United States -- Labor sector UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58848482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=iv%2B361&rft.isbn=&rft.btitle=Preserving+a+strong+United+States+Postal+Service%3A+workforce+issues%3A+hearings%2C+February+4+and+24%2C+2004&rft.title=Preserving+a+strong+United+States+Postal+Service%3A+workforce+issues%3A+hearings%2C+February+4+and+24%2C+2004&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - Supt Docs pa N1 - Document feature - chart(s), il(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Building a national strategy for digital preservation: issues in digital media archiving AN - 57602174; 294484 AB - Book review abstract. Washington, DC: Council on Library and Information Resources and Library of Congress, 2002, 95pp., 20.00 dollars. ISBN 1887334912. Reviewed by Paolina Taglienti. JF - Library Collections, Acquisitions, and Technical Services AU - Library of Congress, Washington DC, USA Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 241 EP - 242 VL - 28 IS - 2 SN - 1464-9055, 1464-9055 KW - Building a national strategy for digital preservation KW - Book review abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57602174?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Alisa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Library+Collections%2C+Acquisitions%2C+and+Technical+Services&rft.atitle=Building+a+national+strategy+for+digital+preservation%3A+issues+in+digital+media+archiving&rft.au=Library+of+Congress%2C+Washington+DC%2C+USA&rft.aulast=Library+of+Congress&rft.aufirst=Washington&rft.date=2004-01-01&rft.volume=28&rft.issue=2&rft.spage=241&rft.isbn=&rft.btitle=&rft.title=Library+Collections%2C+Acquisitions%2C+and+Technical+Services&rft.issn=14649055&rft_id=info:doi/ LA - English DB - Library & Information Science Abstracts (LISA) N1 - Date revised - 2005-05-24 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Book review abstracts; Building a national strategy for digital preservation ER - TY - BOOK T1 - Foreign relations of the United States, 1964-1968.Vol.19:Arab-Israeli crisis and war, 1967 AN - 43667031; M348653 Y1 - 2004 PY - 2004 DA - 2004 SP - 1 EP - 1087 PB - U.S. Government Printing Office KW - Arab-Israeli conflict - 1948-67 KW - United States of America (USA) KW - Documentation, "grey literature", etc. KW - ISR.HIS.1967:Israel, Palestine Territories, Arab-Israeli conflict History 1967-1991 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/43667031?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Index+Islamicus&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=1087&rft.isbn=&rft.btitle=Foreign+relations+of+the+United+States%2C+1964-1968.Vol.19%3AArab-Israeli+crisis+and+war%2C+1967&rft.title=Foreign+relations+of+the+United+States%2C+1964-1968.Vol.19%3AArab-Israeli+crisis+and+war%2C+1967&rft.issn=&rft_id=info:doi/ LA - English DB - Index Islamicus N1 - Last updated - 2016-07-11 ER - TY - JOUR T1 - 'The osage tribe. The rite of virgil', thirty-nineth annual report of the bureau, American ethnology AN - 38184661; 2976273 JF - Année sociologique AU - Flesche, Francis La AU - M., M. Y1 - 2004 PY - 2004 DA - 2004 SP - 205 EP - 207 PB - Washington Government Printing Office VL - 54 IS - 1 SN - 0066-2399, 0066-2399 KW - Sociology KW - Tribes KW - Ethnology KW - Ritual KW - Osage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/38184661?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Ann%C3%A9e+sociologique&rft.atitle=%27The+osage+tribe.+The+rite+of+virgil%27%2C+thirty-nineth+annual+report+of+the+bureau%2C+American+ethnology&rft.au=Flesche%2C+Francis+La%3BM.%2C+M.&rft.aulast=Flesche&rft.aufirst=Francis&rft.date=2004-01-01&rft.volume=54&rft.issue=1&rft.spage=205&rft.isbn=&rft.btitle=&rft.title=Ann%C3%A9e+sociologique&rft.issn=00662399&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - Osage; 12996 4424; 11045 3237 12867; 4469 1077; 12008 ER - TY - JOUR T1 - 'The Osage tribe. Rite of the chiefs. Sayings of the ancient men', thirty-sixth annual report of the bureau of American ethnology AN - 38183509; 2976272 JF - Année sociologique AU - Flesche, Francis La AU - Mauss, M AU - Mauss, M Y1 - 2004 PY - 2004 DA - 2004 SP - 205 EP - 204 PB - Washington Government Printing office VL - 54 IS - 1 SN - 0066-2399, 0066-2399 KW - Sociology KW - Tribes KW - Ethnology KW - Osage KW - Ritual UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/38183509?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Ann%C3%A9e+sociologique&rft.atitle=%27The+Osage+tribe.+Rite+of+the+chiefs.+Sayings+of+the+ancient+men%27%2C+thirty-sixth+annual+report+of+the+bureau+of+American+ethnology&rft.au=Flesche%2C+Francis+La%3BMauss%2C+M&rft.aulast=Flesche&rft.aufirst=Francis&rft.date=2004-01-01&rft.volume=54&rft.issue=1&rft.spage=205&rft.isbn=&rft.btitle=&rft.title=Ann%C3%A9e+sociologique&rft.issn=00662399&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12996 4424; 11045 3237 12867; Osage; 4469 1077; 12008 ER - TY - BOOK T1 - Migration between states and markets T2 - Research in migration and ethnic relations series AN - 37984804; 2869313 JF - Migration between states and markets AU - Entzinger, H B AU - Martiniello, Marco AU - Wihtol de Wenden, Catherine Y1 - 2004 PY - 2004 DA - 2004 SP - 232 EP - xiv, 232 PB - Ashgate SN - 0754642313 KW - Sociology KW - Labour migration KW - Immigration policy KW - Emigration KW - Immigration KW - State KW - Interethnic relations KW - Market KW - Government policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37984804?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/International+Bibliography+of+the+Social+Sciences+%28IBSS%29&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Entzinger%2C+H+B%3BMartiniello%2C+Marco%3BWihtol+de+Wenden%2C+Catherine&rft.aulast=Entzinger&rft.aufirst=H&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=xiv&rft.isbn=0754642313&rft.btitle=Migration+between+states+and+markets&rft.title=Migration+between+states+and+markets&rft.issn=&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Selected conference papers; Includes bibliographical references and index N1 - Last updated - 2013-09-16 ER - TY - BOOK T1 - Wool: products and markets (13th-20th century) T2 - History, economy and society TT - Wool: products and markets (13th-20th century) AN - 36598139; 3391753 JF - Wool: products and markets (13th-20th century) AU - Fontana, Giovanni Luigi AU - Gayot, Gerard Y1 - 2004 PY - 2004 DA - 2004 SP - 1228 PB - CLEUP SN - 8871786556 KW - Anthropology KW - Economics KW - Economic history KW - Middle Ages KW - Market KW - Textile industry KW - Wool industry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36598139?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/International+Bibliography+of+the+Social+Sciences+%28IBSS%29&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Fontana%2C+Giovanni+Luigi%3BGayot%2C+Gerard&rft.aulast=Fontana&rft.aufirst=Giovanni&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=8871786556&rft.btitle=Wool%3A+products+and+markets+%2813th-20th+century%29&rft.title=Wool%3A+products+and+markets+%2813th-20th+century%29&rft.issn=&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Text in English, French, Italian and Spanish N1 - Last updated - 2013-09-16 ER - TY - JOUR T1 - Implementing evidence in clinical practice: the 'therapies' dilemma AN - 20980392; 8569269 AB - Evidence-based practice involves the application of the best available evidence, often from research findings, into the clinical setting to ensure best practice. This paper discusses some of the issues faced by allied health therapists when attempting to integrate research evidence into their own clinical practice. Of particular concern in allied health research are the methodological flaws, which may seriously affect the capacity of the allied health therapist to use the evidence in their clinical practice. Single therapy intervention research, or research based on an occasion of service does not replicate the model of clinical reasoning that underpins the clinical process, nor the notion of an episode of care that characterizes the allied health therapies. Other issues such as the relevance of outcome measures used in allied health research to potential stakeholders, and the differences between therapy diagnostic criteria and research diagnostic criteria used will also adversely affect the capacity for therapists to use the research evidence. It is imperative that research paradigms begin to address the therapy paradigms, allowing research evidence to reflect the real-world situation. Allied health therapists must take a pro-active stance in the process, through undertaking organized reflective practice and forging links with researchers. Barriers associated with the implementation of evidence-based practice in the allied health professions may be reduced with the publishing of relevant clinically directed research. JF - Physiotherapy AU - Grimmer, Karen AU - Bialocerkowski, Andrea AU - Kumar, Saravana AU - Milanese, Steve AD - School of Health Science, University of South Australia, G.P.O. Box 2471, Adelaide, SA 5001, Australia, karen.grimmer@unisa.edu.au Y1 - 2004 PY - 2004 DA - 2004 SP - 189 EP - 194 PB - Elsevier Science, 360 Park Ave. South New York NY 10010-1710 USA, [mailto:usinfo-f@elsevier.com] VL - 90 IS - 4 SN - 0031-9406, 0031-9406 KW - Physical Education Index KW - Health (care) KW - Barriers KW - Physical therapy KW - Therapy KW - Health KW - Publishing KW - Practice KW - PE 110:Physical Therapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20980392?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Physiotherapy&rft.atitle=Implementing+evidence+in+clinical+practice%3A+the+%27therapies%27+dilemma&rft.au=Grimmer%2C+Karen%3BBialocerkowski%2C+Andrea%3BKumar%2C+Saravana%3BMilanese%2C+Steve&rft.aulast=Grimmer&rft.aufirst=Karen&rft.date=2004-01-01&rft.volume=90&rft.issue=4&rft.spage=189&rft.isbn=&rft.btitle=&rft.title=Physiotherapy&rft.issn=00319406&rft_id=info:doi/10.1016%2Fj.physio.2004.06.007 LA - English DB - Physical Education Index N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Health (care); Barriers; Physical therapy; Therapy; Health; Publishing; Practice DO - http://dx.doi.org/10.1016/j.physio.2004.06.007 ER - TY - JOUR T1 - Decolorisation of natural organic matter by Phanerochaete chrysosporium: the effect of environmental conditions; Decolorisation of natural organic matter by Phanerochaete chrysosporium: the effect of environmental conditions AN - 20960185; 11049111 AB - Phanerochaete chrysosporium was shown to rapidly decolorise a solution of natural organic matter (NOM). The effect of various parameters such as carbon and nitrogen content, pH, ionic strength, NOM concentration and addition of Mn2+ on the colour removal process was investigated. The rapid decolorisation was related to fungal growth and biosorption rather than biodegradation as neither carbon nor nitrogen limitation, nor Mn2+ addition, triggered the decolorisation process. Low pH (pH 3) and increased ionic strength (up to 50 g L-1 added NaCl) led to greater specific removal (NOM/unit biomass), probably due to increased electrostatic bonding between the humic material and the biomass. Adsorption of NOM with viable and inactivated (autoclaved or by sodium azide) fungal pellets occurred within 24 hours and the colour removal depended on the viability, method of inactivation and pH. Colour removal by viable pellets was higher under the same conditions, and this, combined with desorption data, confirmed that fungal metabolic activity was important in the decolorisation process. Overall, removals of up to 40-50% NOM from solution were obtained. Of this, removal by adsorption was estimated as 60-70%, half of which was physicochemical, the other half metabolically-dependent biosorption and bioaccumulation. The remainder was considered to be removed by biodegradation, although some of this may be ascribed to bioaccumulation and metabolically-dependent biosorption. JF - Water Science & Technology: Water Supply AU - Rojek, K AU - Roddick, F A AU - Parkinson, A AD - *Cooperative Research Centre for Water Quality and Treatment (E-mail: Felicity.roddick[at]rmit.edu.au)**Cooperative Research Centre for Water Quality and Treatment (E-mail: Felicity.roddick[at]rmit.edu.au)***School of Civil and Chemical Engineering, RMIT University, GPO Box 2476V, Melbourne, 3001, Australia Y1 - 2004 PY - 2004 DA - 2004 SP - 175 EP - 182 VL - 4 IS - 4 SN - 1606-9749, 1606-9749 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts C: Algology, Mycology & Protozoology; Aqualine Abstracts; Biotechnology and Bioengineering Abstracts; Water Resources Abstracts; Environment Abstracts KW - Adsorption KW - Phanerochaete chrysosporium KW - Color removal KW - Hydrogen Ion Concentration KW - pH effects KW - W 30950:Waste Treatment & Pollution Clean-up KW - V 22300:Methods KW - SW 0810:General KW - AQ 00008:Effects of Pollution KW - ENA 16:Renewable Resources-Water KW - A 01320:Microbial Degradation KW - K 03320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20960185?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Science+%26+Technology%3A+Water+Supply&rft.atitle=Decolorisation+of+natural+organic+matter+by+Phanerochaete+chrysosporium%3A+the+effect+of+environmental+conditions%3B+Decolorisation+of+natural+organic+matter+by+Phanerochaete+chrysosporium%3A+the+effect+of+environmental+conditions&rft.au=Rojek%2C+K%3BRoddick%2C+F+A%3BParkinson%2C+A&rft.aulast=Rojek&rft.aufirst=K&rft.date=2004-01-01&rft.volume=4&rft.issue=4&rft.spage=175&rft.isbn=&rft.btitle=&rft.title=Water+Science+%26+Technology%3A+Water+Supply&rft.issn=16069749&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-10-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - pH effects; Color removal; Hydrogen Ion Concentration; Phanerochaete chrysosporium ER - TY - JOUR T1 - Enhanced biodegradability of UV and VUV pre-treated natural organic matter; Enhanced biodegradability of UV and VUV pre-treated natural organic matter AN - 20960149; 11049104 AB - A systematic investigation of the effectiveness of utilising UV (254 nm) or VUV (254 nm + 185 nm) photo-oxidation followed by biological treatment for the removal of natural organic matter (NOM) from a sample of drinking water was undertaken. The conditions of UV and VUV pre-treatment required to achieve maximum biological removal were determined. Positive correlations were observed between the production of smaller molecular weight molecules as shown by HPSEC and the decrease in dissolved organic carbon with increasing radiation dose. Similarly, the reduction of UV absorbance at 254 nm was found to correlate well with the observed increase in biodegradability of the UV-treated samples. UV pre-treatment resulted in the accumulation of biodegradable compounds from the breakdown of chromophoric material, although significant concentrations of refractory DOC remained even after the largest dose (140 J.cm-2). VUV pretreatment resulted in a rapid rate of mineralisation and fast formation of biodegradable compounds. VUV doses larger than 96 J.cm-2 were observed to reduce the apparent effectiveness of biological treatment. After the experimentally determined optimal VUV dose, approximately 80% of remaining DOC was biodegradable demonstrating that greater total DOC removal was achieved utilising VUV irradiation followed by biological treatment. The smaller doses of radiation required and greater bioavailability make VUV more effective than UV pre-treatment. JF - Water Science & Technology: Water Supply AU - Buchanan, W AU - Roddick, F AU - Porter, N AU - Drikas, M AD - *School of Civil and Chemical Engineering, RMIT University (E-mail: s9706687[at]student.rmit.edu.au; felicity.roddick[at]rmit.edu.au)**School of Civil and Chemical Engineering, RMIT University (E-mail: s9706687[at]student.rmit.edu.au; felicity.roddick[at]rmit.edu.au)***Department of Applied Chemistry, RMIT University (E-mail: nichola.porter[at]rmit.edu.au)****Australian Water Quality Centre, PMB 3, Salisbury, SA 5108, Cooperative Research Centre for Water Quality and Treatment, GPO Box 2476V, Melbourne, Victoria 3001, Australia Y1 - 2004 PY - 2004 DA - 2004 SP - 103 EP - 111 VL - 4 IS - 4 SN - 1606-9749, 1606-9749 KW - Aqualine Abstracts; Pollution Abstracts; Biotechnology and Bioengineering Abstracts; Water Resources Abstracts; Environment Abstracts KW - Absorbance KW - Biodegradation KW - Dissolved organic carbon KW - Biological Treatment KW - P 2000:FRESHWATER POLLUTION KW - SW 0810:General KW - AQ 00008:Effects of Pollution KW - ENA 16:Renewable Resources-Water KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20960149?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Science+%26+Technology%3A+Water+Supply&rft.atitle=Enhanced+biodegradability+of+UV+and+VUV+pre-treated+natural+organic+matter%3B+Enhanced+biodegradability+of+UV+and+VUV+pre-treated+natural+organic+matter&rft.au=Buchanan%2C+W%3BRoddick%2C+F%3BPorter%2C+N%3BDrikas%2C+M&rft.aulast=Buchanan&rft.aufirst=W&rft.date=2004-01-01&rft.volume=4&rft.issue=4&rft.spage=103&rft.isbn=&rft.btitle=&rft.title=Water+Science+%26+Technology%3A+Water+Supply&rft.issn=16069749&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-10-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Dissolved organic carbon; Biodegradation; Biological Treatment ER - TY - JOUR T1 - Sensory-motor deficits in children with developmental coordination disorder, attention deficit hyperactivity disorder and autistic disorder AN - 19507101; 7200669 AB - Children who have been diagnosed with any one developmental disorder are very likely to meet diagnostic criteria for some other developmental disorder. Although comorbidity has long been acknowledged in childhood disorders, little is understood about the mechanisms that are responsible for the high level of comorbidity. In a series of studies, we have investigated the link between sensory-motor deficits and developmental disorders. Poor sensory-motor integration has long been implicated as a cause of motor problems in developmental disorders such as developmental coordination disorder (DCD), and our recent research has also investigated sensory-motor deficits in children with attention deficit hyperactivity disorder (ADHD) and autistic disorder. Based on a critical examination of relevant literature and some of our recent research findings, we argue that the importance of poor sensory-motor functioning in discriminating children with different disorders has been underestimated. Poor sensory-motor coordination appears to be linked to DCD, but not ADHD. Also, sensory-motor deficits in children with DCD and autistic disorder may provide insight into some of the social difficulties found in these groups of children. This research will increase our understanding of why children with one developmental disorder typically also have problems in other areas. JF - Human Movement Science AU - Piek, Jan P AU - Dyck, Murray J AD - School of Psychology, Curtin University of Technology, G.P.O. Box U1987, Perth 6845, Australia, j.piek@curtin.edu.au Y1 - 2004 PY - 2004 DA - 2004 SP - 475 EP - 488 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 23 IS - 3-4 SN - 0167-9457, 0167-9457 KW - Physical Education Index; CSA Neurosciences Abstracts KW - Developmental coordination disorder KW - Attention deficit hyperactivity disorder KW - Visual-spatial perception KW - Autistic disorder KW - Coordination KW - Children KW - Movement KW - Evaluation KW - Integration KW - Literature reviews KW - Autism KW - Attention KW - neurodevelopmental disorders KW - Hyperactivity KW - N3 11001:Behavioral and Cognitive Neuroscience KW - PE 080:Motor Learning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19507101?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+Movement+Science&rft.atitle=Sensory-motor+deficits+in+children+with+developmental+coordination+disorder%2C+attention+deficit+hyperactivity+disorder+and+autistic+disorder&rft.au=Piek%2C+Jan+P%3BDyck%2C+Murray+J&rft.aulast=Piek&rft.aufirst=Jan&rft.date=2004-01-01&rft.volume=23&rft.issue=3-4&rft.spage=475&rft.isbn=&rft.btitle=&rft.title=Human+Movement+Science&rft.issn=01679457&rft_id=info:doi/10.1016%2Fj.humov.2004.08.019 LA - English DB - Physical Education Index N1 - Date revised - 2007-01-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Evaluation; Integration; Coordination; Literature reviews; Children; Movement; Attention; Hyperactivity; Attention deficit hyperactivity disorder; Autism; neurodevelopmental disorders DO - http://dx.doi.org/10.1016/j.humov.2004.08.019 ER - TY - JOUR T1 - SEACORM NET - Southeast Asia's coral reef monitoring network AN - 19449010; 6781674 AB - The region's scientists work together to formed the SEACORM Net (Southeast Asia Coral Reef Monitoring Network)for better integration of information and resources. The group intends to establish a strong working relationship between member countries, share information and lessons learnt, inform and update each other on research and monitoring activities in each country, and provide a mechanism for cross-country assistance and collaboration. JF - NAGA AU - Tun, K AU - Chou, L M AD - The WorldFish Center, P.O. Box 500, GPO, 10670 Penang Malaysia, k.tun@cgiar.org Y1 - 2004///0, PY - 2004 DA - 0, 2004 SP - 54 VL - 27 IS - 1-2 SN - 1511-8533, 1511-8533 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Marine KW - Resource management KW - Information handling KW - Coral reefs KW - Southeast Asia KW - Monitoring KW - Q5 08523:Conservation, wildlife management and recreation KW - Q1 08463:Habitat community studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19449010?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=NAGA&rft.atitle=SEACORM+NET+-+Southeast+Asia%27s+coral+reef+monitoring+network&rft.au=Tun%2C+K%3BChou%2C+L+M&rft.aulast=Tun&rft.aufirst=K&rft.date=2004-01-01&rft.volume=27&rft.issue=1-2&rft.spage=54&rft.isbn=&rft.btitle=&rft.title=NAGA&rft.issn=15118533&rft_id=info:doi/ L2 - http://www.worldfishcenter.org/naga/naga27-1n2/pdf/article-10.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-04-01 N1 - SuppNotes - Physical medium: Printed matter, Internet; http://www.worldfishcenter.org/naga/naga27-1n2/pdf/article-10.pdf N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Resource management; Information handling; Coral reefs; Monitoring; Southeast Asia; Marine ER - TY - JOUR T1 - No Detectable Improvement in Compliance to Regulations by "Swim-With-DoIphin" Operators in Port Phillip Bay, Victoria, Australia AN - 19383438; 8573672 AB - This article reports on operator compliance with regulations regarding humans swimming with free-ranging bottlenose dolphins (Tursiops sp.) in Port Phillip Bay, Victoria, Australia. The objective of this study was to compare if the level of compliance to three conditions (approach type, swim time, and time in proximity to dolphins) in the tour operators' permits changed after state government conducted a review on the existing operators. An additional fourth condition (number of swimmers participating in a dolphin-swim) was also studied. A total of 128 commercial dolphin-swim trips from September 1998-April 1999 and September 1999-April 2000 (prereview) and 16 commercial dolphin-swim trips from February-March 2002 and January 2003 (postreview) were studied. Data were collected using 1-minute scan samples and continuous observations from all three operating human-dolphin-swim tourist vessels. There was no detectable change in the level of compliance for rules regarding the way boats approached dolphins, their time in the proximity of dolphins, and the length of time people swam with dolphins. Operators always complied with regulations regarding the number of people participating in a dolphin-swim. Investigations of the extent to which tourism affects cetaceans have tended to ignore whether tourist vessels obey existing regulations. This study demonstrates that compliance cannot be assumed, and that operators appear to comply better with conditions that are easily quantified. Further, studies are needed to determine the statistical power required to detect changes in tour operator behavior to conditions in their permits. This will inform agencies whether the changes they have implemented to improve compliance levels are actually working. JF - Tourism in Marine Environments AU - Scarpaci, C AU - Nugegoda, D AU - Corkeron, P J AD - RMIT University, Australia, School of Applied Science, Bundoora Campus, GPO Box 71, Bundoora, Victoria, Australia Y1 - 2004 PY - 2004 DA - 2004 SP - 41 EP - 48 VL - 1 IS - 1 SN - 1544-273X, 1544-273X KW - Sustainability Science Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Tourism KW - Marine KW - Tursiops KW - dolphins KW - Compliance KW - boats KW - Environmental factors KW - tour operators KW - PSE, Australia, Victoria, Port Phillip Bay KW - Marine environment KW - Reviews KW - Marine mammals KW - Permits KW - M3 1010:Issues in Sustainable Development KW - Q1 08423:Behaviour KW - Q5 08501:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19383438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tourism+in+Marine+Environments&rft.atitle=No+Detectable+Improvement+in+Compliance+to+Regulations+by+%22Swim-With-DoIphin%22+Operators+in+Port+Phillip+Bay%2C+Victoria%2C+Australia&rft.au=Scarpaci%2C+C%3BNugegoda%2C+D%3BCorkeron%2C+P+J&rft.aulast=Scarpaci&rft.aufirst=C&rft.date=2004-01-01&rft.volume=1&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Tourism+in+Marine+Environments&rft.issn=1544273X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Tourism; Marine mammals; Environmental factors; Marine environment; Reviews; dolphins; boats; Compliance; Permits; tour operators; Tursiops; PSE, Australia, Victoria, Port Phillip Bay; Marine ER - TY - JOUR T1 - Invasion rates increase with species richness in a marine epibenthic community by two mechanisms AN - 19266021; 5836432 AB - It is widely believed that, when extrinsic conditions are similar, the likelihood of species invading established assemblages decreases with increasing species richness of the recipient community. Here we show that, for a sessile marine invertebrate community, invasion of patches increases with richness of the patch. We show that invasions can increase with local species richness by two distinct mechanisms. In the first, opportunistic colonisers with traits typical of invasive species colonise species-rich patches at higher rates because speciose patches are dominated by small colonies and mortality rates of small colonies are greater than that of large ones. Thus, mortality provides bare space for opportunists to colonise more frequently in species-rich patches. In the second, some species avoid colonising open areas of free space but preferentially associate with established colonies of particular other species, and a given preferred associate is more likely to occur in species-rich than in species-poor patches. These patterns are the result of particular properties of individual species and local species dynamics, and show that reduced risk of invasion is not necessarily an intrinsic property of species-rich communities. We conclude that resistance to invasion will be determined by the properties of the particular component species and emergent dynamics of the recipient community, and not by an aggregate community property such as richness. JF - Oecologia AU - Dunstan, P K AU - Johnson, C R AD - School of Zoology and Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, GPO Box 252-05, 7001, Hobart, Tasmania, Australia, Piers.Dunstan@csiro.au Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 285 EP - 292 PB - Springer-Verlag VL - 138 IS - 2 SN - 0029-8549, 0029-8549 KW - ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; Ecology Abstracts KW - Marine KW - Marine invertebrates KW - Biological diversity KW - Biodiversity KW - Colonization KW - Community composition KW - Environmental effects KW - Invasions KW - Introduced species KW - Benthos KW - Q1 08462:Benthos KW - D 04330:Marine KW - Q1 08422:Environmental effects KW - O 1030:Invertebrates UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19266021?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Oecologia&rft.atitle=Invasion+rates+increase+with+species+richness+in+a+marine+epibenthic+community+by+two+mechanisms&rft.au=Dunstan%2C+P+K%3BJohnson%2C+C+R&rft.aulast=Dunstan&rft.aufirst=P&rft.date=2004-01-01&rft.volume=138&rft.issue=2&rft.spage=285&rft.isbn=&rft.btitle=&rft.title=Oecologia&rft.issn=00298549&rft_id=info:doi/10.1007%2Fs00442-003-1400-7 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Colonization; Community composition; Marine invertebrates; Environmental effects; Biodiversity; Introduced species; Benthos; Invasions; Biological diversity; Marine DO - http://dx.doi.org/10.1007/s00442-003-1400-7 ER - TY - JOUR T1 - Impact of soil warming and shading on colonization and community structure of arbuscular mycorrhizal fungi in roots of a native grassland community AN - 19263266; 5826358 AB - Arbuscular mycorrhizal (AM) fungi have a major influence on the structure, responses and below-ground C allocation of plant communities. Our lack of understanding of the response of AM fungi to factors such as light and temperature is an obstacle to accurate prediction of the impact of global climate change on ecosystem functioning. In order to investigate this response, we divided a grassland site into 24 plots, each either unshaded or partly shaded with soil either unheated or heated by 3 degree C at 2 cm depth. In both short-term studies in spring and autumn, and in a 1-year-long study, we measured root length colonization (L sub(R)C) by AM and non-AM fungi. For selected root samples, DNA sequences were amplified by PCR with fungal-specific primers for part of the small sub-unit (SSU) rRNA gene. In spring, the total L sub(R)C increased over 6 weeks from 12% to 25%. Shading significantly reduced AM but increased non-AM fungal colonization, while soil warming had no effect. In the year-long study, colonization by AM fungi peaked in summer, whereas non-AM colonization peaked in autumn, when there was an additive effect of shading and soil warming that reduced AM but increased non-AM fungi. Stepwise regression revealed that light received within the 7 days prior to sampling was the most significant factor in determining AM L sub(R)C and that mean temperature was the most important influence on non-AM L sub(R)C. Loglinear analysis confirmed that there were no seasonal or treatment effects on the host plant community. Ten AM fungal sequence types were identified that clustered into two families of the Glomales, Glomaceae and Gigasporaceae. Three other sequence types were of non-AM fungi, all Ascomycotina. AM sequence types showed seasonal variation and shading impacts: loglinear regression analysis revealed changes in the AM fungal community with time, and a reduction of one Glomus sp. under shade, which corresponded to a decrease in the abundance of Trifolium repens. We suggest that further research investigating any impacts of climate change on ecosystem functioning must not only incorporate their natural AM fungal communities but should also focus on niche separation and community dynamics of AM fungi. JF - Global Change Biology AU - Heinemeyer, A AU - Ridgway, K P AU - Edwards, E J AU - Benham, D G AU - Young, J P AU - Fitter, AH AD - Department of Biology, Stockholm Environment Institute-York (SEI-Y), University of York, York YO10 5YW, UK, Department of Biology, University of York, York YO10, 5YW, UK, Research School of Biological Sciences, Australian National University, G.P.O. Box 475, Canberra ACT 2601, Australia, Centre for Ecology and Hydrology, Merlewood Research Station, Grange-over-Sands, Cumbria LA11 6JU, UK, ah126@york.ac.uk Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 52 EP - 64 PB - Blackwell Science Ltd VL - 10 IS - 1 SN - 1354-1013, 1354-1013 KW - White clover KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts KW - Ecosystems KW - Niches KW - Niche breadth KW - Abundance KW - Roots KW - Glomus KW - Soil microorganisms KW - Soil KW - Colonization KW - Shading KW - Temperature effects KW - Mycorrhizas KW - Trifolium repens KW - Light effects KW - Community structure KW - arbuscular mycorrhizas KW - D 04623:Fungi KW - K 03096:Mycorrhiza UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19263266?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+Change+Biology&rft.atitle=Impact+of+soil+warming+and+shading+on+colonization+and+community+structure+of+arbuscular+mycorrhizal+fungi+in+roots+of+a+native+grassland+community&rft.au=Heinemeyer%2C+A%3BRidgway%2C+K+P%3BEdwards%2C+E+J%3BBenham%2C+D+G%3BYoung%2C+J+P%3BFitter%2C+AH&rft.aulast=Heinemeyer&rft.aufirst=A&rft.date=2004-01-01&rft.volume=10&rft.issue=1&rft.spage=52&rft.isbn=&rft.btitle=&rft.title=Global+Change+Biology&rft.issn=13541013&rft_id=info:doi/10.1111%2Fj.1365-2486.2003.00713.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Glomus; Trifolium repens; Mycorrhizas; Community structure; Soil microorganisms; Colonization; Temperature effects; Light effects; Niche breadth; Shading; Abundance; Ecosystems; Soil; Niches; arbuscular mycorrhizas; Roots DO - http://dx.doi.org/10.1111/j.1365-2486.2003.00713.x ER - TY - JOUR T1 - Introduced and cryptogenic species in Port Phillip Bay, Victoria, Australia AN - 19223621; 5807808 AB - Port Phillip Bay (PPB) is a large (1,930 km super(2)), temperate embayment in southern Victoria, Australia. Extensive bay-wide surveys of PPB have occurred since 1840. In 1995/1996 the Commonwealth Scientific and Industrial Research Organization (CSIRO) Centre for Research on Introduced Marine Pests (CRIMP) undertook an intensive evaluation of the region with the aims of developing a comprehensive species list of native and introduced biota and contrasting previous bay-wide assessments with a current field survey in order to detect new incursions and discern alterations to native communities. Two methods were used to meet these aims: a re-evaluation of regional museum collections and published research in PPB to identify and determine the timing of introductions; and field surveys for benthic (infauna, epifauna and encrusting) organisms between September 1995 to March 1996. One hundred and sixty introduced (99) and cryptogenic (61) species were identified representing over 13% of the recorded species of PPB. As expected, the majority of these are concentrated around the shipping ports of Geelong and Melbourne. Invasions within PPB appear to be increasing, possibly due to an increase in modern shipping traffic and an increase in aquaculture (historically associated with incidental introductions); however the records of extensive biological surveys suggest that this may, in part, be an artefact of sampling effort. In contrast to Northern Hemisphere studies, PPB (and Southern Hemisphere introductions in general) have significantly different suites of successfully invading taxa. PPB is presented as one of the most invaded marine ecosystems in the Southern Hemisphere. JF - Marine Biology AU - Hewitt, CL AU - Campbell, M L AU - Thresher, R E AU - Martin, R B AU - Boyd, S AU - Cohen, B F AU - Currie AU - Gomon, M F AU - Keough, MJ AU - Lewis, JA AU - Lockett, M M AU - Mays, N AU - McArthur, MA AU - O'Hara, T D AU - Poore, G C AU - Ross, D J AU - Storey, MJ AU - Watson, JE AU - Wilson, R S AD - Centre for Research on Introduced Marine Pests, CSIRO Marine Research, GPO Box 1538, 7001, Hobart, Tasmania, Australia, chad.hewitt@fish.govt.nz Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 183 EP - 202 PB - Springer-Verlag VL - 144 IS - 1 SN - 0025-3162, 0025-3162 KW - CSIRO KW - Centre for Research on Introduced Pests KW - Cryptogenic species KW - Invasive species KW - Species of unknown origin KW - Oceanic Abstracts; Ecology Abstracts KW - New records KW - Biological surveys KW - Marine KW - Australia, Victoria KW - Check lists KW - Museum collections KW - Epibionts KW - PSE, Australia, Victoria, Port Phillip Bay KW - Distribution records KW - Analytical techniques KW - Marine ecosystems KW - Zoobenthos KW - Introduced species KW - Fouling organisms KW - Benthos KW - Bays KW - O 1070:Ecology/Community Studies KW - D 04330:Marine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19223621?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Biology&rft.atitle=Introduced+and+cryptogenic+species+in+Port+Phillip+Bay%2C+Victoria%2C+Australia&rft.au=Hewitt%2C+CL%3BCampbell%2C+M+L%3BThresher%2C+R+E%3BMartin%2C+R+B%3BBoyd%2C+S%3BCohen%2C+B+F%3BCurrie%3BGomon%2C+M+F%3BKeough%2C+MJ%3BLewis%2C+JA%3BLockett%2C+M+M%3BMays%2C+N%3BMcArthur%2C+MA%3BO%27Hara%2C+T+D%3BPoore%2C+G+C%3BRoss%2C+D+J%3BStorey%2C+MJ%3BWatson%2C+JE%3BWilson%2C+R+S&rft.aulast=Hewitt&rft.aufirst=CL&rft.date=2004-01-01&rft.volume=144&rft.issue=1&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Marine+Biology&rft.issn=00253162&rft_id=info:doi/10.1007%2Fs00227-003-1173-x L2 - http://link.springer.de/link/service/journals/00227/bibs/4144001/41440183.htm LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Biological surveys; New records; Epibionts; Distribution records; Analytical techniques; Check lists; Museum collections; Introduced species; Zoobenthos; Fouling organisms; Bays; Marine ecosystems; Benthos; PSE, Australia, Victoria, Port Phillip Bay; Australia, Victoria; Marine DO - http://dx.doi.org/10.1007/s00227-003-1173-x ER - TY - JOUR T1 - Comparison of Agrobacterium-mediated transformation of four barley cultivars using the GFP and GUS reporter genes AN - 19222117; 5808047 AB - Experiments were conducted to produce transgenic barley plants following infection of immature embryos with Agrobacterium tumefaciens. Transformed callus was obtained using hygromycin resistance as a selectable marker and either green fluorescent protein (GFP) or beta -glucuronidase (GUS) as a reporter. Significantly reduced plant transformation frequencies were obtained with the GFP gene compared to GUS. However, GFP proved to be an excellent reporter of early transformation events and was used to compare four barley cultivars for efficiency in two phases of transformation: the generation of stably transformed barley callus and the regeneration of plantlets from transformed callus. Transformed callus was generated at a high frequency (47-76%) in all four cultivars. Regeneration of transformed plantlets was also achieved for all four cultivars although the frequency was much higher for Golden Promise than for the other three genotypes, reiterating that genotype is an important determinant in the regenerative ability of barley. This study has demonstrated for the first time that Agrobacterium-mediated transformation can be used to transform the Australian cultivars Sloop and Chebec. JF - Plant Cell Reports AU - Murray, F AU - Brettell, R AU - Matthews, P AU - Bishop, D AU - Jacobsen, J AD - CSIRO Plant Industry, GPO Box 1600, ACT 2601, Canberra, Australia Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 397 EP - 402 PB - Springer-Verlag VL - 22 IS - 6 SN - 0721-7714, 0721-7714 KW - Barley KW - hygromycin KW - Biotechnology and Bioengineering Abstracts; Genetics Abstracts; Agricultural and Environmental Biotechnology Abstracts; Bioengineering Abstracts KW - Transformation KW - Hordeum vulgare KW - ^b-Glucuronidase KW - Green fluorescent protein KW - Callus KW - Genotypes KW - Transgenic plants KW - b-Glucuronidase KW - Agrobacterium KW - Regeneration KW - Antibiotic resistance KW - G 07358:Monocotyledons (crops) KW - W2 32065:Plants KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19222117?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Cell+Reports&rft.atitle=Comparison+of+Agrobacterium-mediated+transformation+of+four+barley+cultivars+using+the+GFP+and+GUS+reporter+genes&rft.au=Murray%2C+F%3BBrettell%2C+R%3BMatthews%2C+P%3BBishop%2C+D%3BJacobsen%2C+J&rft.aulast=Murray&rft.aufirst=F&rft.date=2004-01-01&rft.volume=22&rft.issue=6&rft.spage=397&rft.isbn=&rft.btitle=&rft.title=Plant+Cell+Reports&rft.issn=07217714&rft_id=info:doi/10.1007%2Fs00299-003-0704-8 L2 - http://link.springer.de/link/service/journals/00299/bibs/4022006/40220397.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Agrobacterium; Hordeum vulgare; Green fluorescent protein; Transgenic plants; Genotypes; Regeneration; Callus; Antibiotic resistance; b-Glucuronidase; Transformation; ^b-Glucuronidase DO - http://dx.doi.org/10.1007/s00299-003-0704-8 ER - TY - JOUR T1 - Timing of early amniocentesis as a function of membrane fusion AN - 19204066; 5795621 AB - The purpose of this prospective study was to evaluate sonographically the timing of membrane fusion and to determine its possible effect on the timing of amniocentesis. Between May 18, 1998, and January 31, 2002, the status of amnion fusion in pregnant patients at 9-15 weeks' menstrual age was identified in women who were to undergo obstetric sonography. Amniocentesis was performed if even a small area of fused membranes that could be traversed was identified; if the membranes were completely unfused, amniocentesis was delayed. The effect of membrane fusion in terms of the need to reschedule amniocentesis was evaluated. We examined a total of 594 patients. Membrane fusion occurred progressively with increasing menstrual age. One hundred six early amniocenteses were scheduled, and 70 were performed; the others were delayed because the membranes were unfused. Our requirement that an area of membrane fusion be found before we would perform amniocentesis resulted in rescheduling the procedure 24-38% of the time. Membrane fusion, as seen sonographically, is a function of menstrual age. Even by 15 weeks, a portion of the amnion may be unfused with the chorion. Amniocenteses scheduled for early in the pregnancy may need to be delayed until later, when the membranes are at least partially fused, allowing safe passage of a needle. Delaying the procedure may incur higher expense but may be important in terms of lessening the risk involved. JF - Journal of Clinical Ultrasound AU - Pinette, M G AU - Wax, J AU - Blackstone, J AU - Cartin, A AU - McCrann, D AD - Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Maine Medical Center, 887 Congress Street, Suite 200, Portland, Maine 04102 Y1 - 2004 PY - 2004 DA - 2004 SP - 8 EP - 11 PB - John Wiley & Sons, Ltd., Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk], [URL:http://www.wiley.com/] VL - 32 IS - 1 SN - 0091-2751, 0091-2751 KW - man KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Menstrual cycle KW - Amniocentesis KW - Membrane fusion KW - Ultrasonography KW - Ultrasound KW - Pregnancy KW - W4 150:Medical Imaging KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19204066?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Ultrasound&rft.atitle=Timing+of+early+amniocentesis+as+a+function+of+membrane+fusion&rft.au=Pinette%2C+M+G%3BWax%2C+J%3BBlackstone%2C+J%3BCartin%2C+A%3BMcCrann%2C+D&rft.aulast=Pinette&rft.aufirst=M&rft.date=2004-01-01&rft.volume=32&rft.issue=1&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Ultrasound&rft.issn=00912751&rft_id=info:doi/10.1002%2Fjcu.10214 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Ultrasound; Ultrasonography; Amniocentesis; Membrane fusion; Pregnancy; Menstrual cycle DO - http://dx.doi.org/10.1002/jcu.10214 ER - TY - JOUR T1 - Modelling the growth and water uptake function of plant root systems: a review AN - 18062324; 5989611 AB - Crop models have been intensively used as a tool to analyse the performance of cropping systems under variable climate in terms of productivity, profitability, and off-site impact. The importance of modelling the function of plant roots in water and nutrient uptake from the soil is becoming increasing clear with the expanding application areas of crop models. This paper reviews the approaches and assumptions used in growth and uptake modelling of plant roots, and how the responses of plant root system to internal and external factors are captured in the widely used crop models. Most modelling approaches are based on one of the following assumptions: (i) that plant roots are uniformly distributed in homogenous soil layers and all roots have the same ability for uptake, or (ii) that plant root length is always sufficient for resource uptake in rooted soil layers. In structured soils, an overestimation of water uptake is likely to be expected. Further studies on root growth, distribution, and function in structured soils will require quantification of soil structures and root distribution patterns; and for non-uniformly distributed plant populations, spatial distribution of plant roots and non-uniform uptake need to be modelled. Root architecture modelling may help to address such issues. However, in order for the model to be useful at the field production level, simplified approaches that require easily measurable inputs need to be developed. Some examples are given. The oversimplification of root response to soil drying and hardness is likely to lead to overestimation of root growth and water uptake in dense soils. A soil strength factor needs to be incorporated so that the improved model can help evaluate the effect of subsoil compaction on production and resource use. Responses of root growth and uptake to soil salinity, boron toxicity, and extreme pH need to be further investigated if models are to be used for evaluation of crop performance in such environments. Effect of waterlogging also needs to be added for use of the model on heavy clay soils under irrigation or concentrated rainfall. There is an urgent need for joint efforts of crop physiologists, agronomists, breeders, and soil scientists to integrate interdisciplinary knowledge and to collect data that better describe the crop root system and its growth and uptake ability, to quantify plant process level responses, and for better soil quantification. Such knowledge and data are essential for improvement of model performance and successful applications. JF - Australian Journal of Agricultural Research AU - Wang, E AU - Smith, C J AD - CSIRO Land and Water/Agricultural Production Systems Research Unit, GPO Box 1666 (Clunnies Ross St), Canberra, ACT 2601, Australia, Enli.Wang@csiro.au Y1 - 2004 PY - 2004 DA - 2004 SP - 501 EP - 523 VL - 55 IS - 5 SN - 0004-9409, 0004-9409 KW - Water Resources Abstracts KW - Agriculture KW - Nutrients KW - Soil-water-plant Relationships KW - Crops KW - Model Studies KW - SW 0860:Water and plants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18062324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Agricultural+Research&rft.atitle=Modelling+the+growth+and+water+uptake+function+of+plant+root+systems%3A+a+review&rft.au=Wang%2C+E%3BSmith%2C+C+J&rft.aulast=Wang&rft.aufirst=E&rft.date=2004-01-01&rft.volume=55&rft.issue=5&rft.spage=501&rft.isbn=&rft.btitle=&rft.title=Australian+Journal+of+Agricultural+Research&rft.issn=00049409&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Crops; Soil-water-plant Relationships; Nutrients; Model Studies; Agriculture ER - TY - JOUR T1 - Uptake, retention and organ/tissue distribution of super(137)Cs by Japanese catfish (Silurus asotus Linnaeus) AN - 18054627; 6082042 AB - This paper describes the uptake, retention/biological elimination and organ/tissue distribution of super(137)Cs by freshwater Japanese catfish (Silurus asotus Linnaeus) under laboratory conditions. The fish were divided into three groups based on their size and age and reared in super(137)Cs-spiked water. The concentration of super(137)Cs in the whole body of the live fish was measured at regular intervals up to 60 days. A significant accumulation of super(137)Cs was found, but a steady state condition was not achieved by the end of the experiment. The bioaccumulation factors at steady state and the required time to reach steady state were estimated to be 1.55 and 255 days, 1.76 and 180 days and 1.99 and 160 days for large, medium and small size fish, respectively. To determine the effective half-life of super(137)Cs, the fish were transferred and reared in the non-contaminated host water. The concentration of the remaining super(137)Cs in the whole body of the live fish was measured up to 66 days. The average effective half-life of super(137)Cs in the fish species was found to be approximately 142 days for fish of all sizes. The distribution of super(137)Cs in different organs/tissues of the fish was determined. Accumulation of super(137)Cs in muscle/flesh of the fish was found to be approximately 75% of whole body accumulation. The uptake rate and the retention capability of juvenile fish were found to be higher and therefore, these were more susceptible to super(137)Cs than adult and old fish, and could be an important source of super(137)Cs in the human food chain. JF - Journal of environmental radioactivity AU - Malek, MA AU - Nakahara, M AU - Nakamura, R AD - Health Physics Division, Atomic Energy Center, 4 Kazi Nazrul Islam Avenue, GPO Box-164, Ramna, Dhaka 1000 Bangladesh, z_mam@yahoo.com Y1 - 2004 PY - 2004 DA - 2004 SP - 191 EP - 204 VL - 77 IS - 2 SN - 0265-931X, 0265-931X KW - Freshwater catfishes KW - Sheatfishes KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA Aquaculture Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Chemical equilibrium KW - Radioactive pollutants KW - Human food KW - Caesium 137 KW - Biological age KW - Water temperature KW - Cultured organisms KW - Freshwater KW - Freshwater fish KW - Chemical kinetics KW - Risks KW - Self purification KW - Public health KW - Siluridae KW - Bioaccumulation KW - Silurus asotus KW - Body size KW - Radioisotopes KW - Controlled conditions KW - Biological half life KW - Aquaculture products KW - Fish culture KW - Q5 08504:Effects on organisms KW - Q3 08582:Fish culture KW - Q5 08524:Public health, medicines, dangerous organisms KW - Q1 08627:Food quality and standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18054627?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+radioactivity&rft.atitle=Uptake%2C+retention+and+organ%2Ftissue+distribution+of+super%28137%29Cs+by+Japanese+catfish+%28Silurus+asotus+Linnaeus%29&rft.au=Malek%2C+MA%3BNakahara%2C+M%3BNakamura%2C+R&rft.aulast=Malek&rft.aufirst=MA&rft.date=2004-01-01&rft.volume=77&rft.issue=2&rft.spage=191&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+radioactivity&rft.issn=0265931X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Physical medium: Printed matter N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Chemical equilibrium; Radioactive pollutants; Caesium 137; Human food; Cultured organisms; Water temperature; Biological age; Chemical kinetics; Freshwater fish; Risks; Public health; Self purification; Bioaccumulation; Radioisotopes; Body size; Controlled conditions; Biological half life; Fish culture; Aquaculture products; Siluridae; Silurus asotus; Freshwater ER - TY - BOOK T1 - Diatom assemblages as indicators of wastewater discharge in a temporary stream in Western Australia AN - 18038909; 5995684 AB - Clearing of native vegetation and subsequent intense agriculture over the past 170 years have resulted in many streams in the semi-arid zones of southwestern Australia showing symptoms of salinisation and eutrophication. Human settlements have contributed further to the nutrient enrichment of the streams as effluent from the wastewater processing plants has been discharged into the streams. This paper deals with the case history of Narrogin Brook - an ephemeral stream in the southwest of Western Australia - that has been subjected to salinisation, eutrophication and wastewater discharge. Diatom assemblages from seven sites sampled by an artificial substrate collector once in winter and spring of 2001 were analysed in conjunction with the environmental variables. The impact of salinisation and eutrophication was reflected by the low species richness and dominance of the diatom species - Bacillaria paxillifer, Gomphonema parvulum, Thalassiosira Weissflogii, Nitzschia frustulum and Navicula salinarum. The distribution pattern of diatoms in the stream showed significant changes in community structure in accordance with the environmental changes. The impact of wastewater discharge could be distinguished from that caused by salinisation both in terms of water quality parameters and diatom community structure. Problems of standardising a biomonitoring protocol to gauge the impact of land use and wastewater discharge on temporary streams are discussed JF - Proceedings of the seventeenth International Diatom Symposium. AU - John, J Y1 - 2004 PY - 2004 DA - 2004 SP - 17 EP - 145 PB - Biopress, Bristol (UK) SN - 0948737700 KW - ASFA 3: Aquatic Pollution & Environmental Quality KW - Community composition KW - Eutrophication KW - Temporary ponds KW - Salinity effects KW - Bacillariophyceae KW - Freshwater KW - Australia, Western Australia, Narrogin Brook KW - Waste water KW - Water quality KW - Monitoring systems KW - Indicator species KW - Q5 08504:Effects on organisms KW - Q5 08502:Methods and instruments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18038909?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Aquatic+Science+%26+Fisheries+Abstracts+%28ASFA%29+3%3A+Aquatic+Pollution+%26+Environmental+Quality&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=John%2C+J&rft.aulast=John&rft.aufirst=J&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=129&rft.isbn=0948737700&rft.btitle=Diatom+assemblages+as+indicators+of+wastewater+discharge+in+a+temporary+stream+in+Western+Australia&rft.title=Diatom+assemblages+as+indicators+of+wastewater+discharge+in+a+temporary+stream+in+Western+Australia&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Physical medium: Printed matter N1 - Last updated - 2014-05-07 ER - TY - JOUR T1 - Commercialisation of biotechnology: public trust and research AN - 18035067; 5994300 AB - The success of the biotechnology revolution depends on an array of interwoven factors, not the least of which is the protection, preservation and promotion of public trust in the science, the scientists and the regulators. This paper considers some of the areas in which the commercialisation of biotechnology research may affect public trust. The increasing involvement of the private sector in basic research and the need for the public sector to commercialise its research has resulted in a blurring of the divide between the two sectors. The expanding public and private partnerships are creating an elision between the two sectors. In biotechnology, knowledge itself has become commodified and subject to confidentiality agreements and patent protections. These trends are challenging the traditional science norms of universalism, collegiality, disinterestedness and organised scepticism. These trends may equally have a detrimental flow on effect in relation to public trust in science. This paper considers and emphasises the appropriate roles of regulation, public consultation and corporate social responsibility and benefit sharing in protecting and restoring the key factor of public trust. JF - International Journal of Biotechnology AU - Chalmers, D AU - Nicol, D AD - University of Tasmania, Private Bag-89, GPO Hobart, Tas. 7001, Australia, Dianne.Nicol@utas.edu.au Y1 - 2004 PY - 2004 DA - 2004 SP - 116 EP - 133 VL - 6 IS - 2-3 SN - 0963-6048, 0963-6048 KW - Biotechnology and Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - Research programs KW - Public health KW - W2 32000:General topics and reviews KW - W 30965:Miscellaneous, Reviews KW - W3 33000:General topics and reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18035067?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Biotechnology&rft.atitle=Commercialisation+of+biotechnology%3A+public+trust+and+research&rft.au=Chalmers%2C+D%3BNicol%2C+D&rft.aulast=Chalmers&rft.aufirst=D&rft.date=2004-01-01&rft.volume=6&rft.issue=2-3&rft.spage=116&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Biotechnology&rft.issn=09636048&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - SuppNotes - Special Issue: Commercialisation of Biotechnology Research and Innovation. N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Research programs; Public health ER - TY - JOUR T1 - Health implication among occupational exposed workers in a chromium alloy factory, Thailand AN - 17997731; 5937734 AB - This study was conducted to assess the occupational exposure and its health impact on the chromium alloy workers. Environmental and biological monitoring, noise and audiometry measurements were done to evaluate the exposure levels in the factory. A total of 112 non-smoking workers were monitored from July 2001 to August 2002. The results showed that most of the chromium and lead exposures in the factory were below the ACGIH-TWA of 50 mu g/m super(3) for chromium(VI) and OSHA-PEL of 50 mu g/m super(3) for lead. The highest chromium (7.25 plus or minus 0.16 mu g/m super(3)) and lead (14.50 plus or minus 0.29 mu g/m super(3)) concentrations were measured in the vibro room. The results indicated that elevated concentrations of chromium and lead were found in both blood and urine samples especially in those areas which were characterized by poor ventilation. The metal contents in blood and urine samples were significantly correlated with airborne metal concentrations in the factory. The result demonstrated that blood and urinary levels among workers were associated with increasing age and duration of exposure. The background noise level of the factory ranged from 67.6 to 89.2 dBA and was frequently higher than the threshold limit value for noise (90 dBA). According to the audiometric test, the exposed workers showed signs of noise-induced hearing loss. Noise at work continued to be an important factor to hearing loss among exposed workers. In our statistical analysis, a significant hearing loss was established on age effect and year of exposure among the workforce. JF - Journal of Environmental Sciences (China) AU - Muttamara, S AU - Leong, ST AD - Urban Environmental Engineering and Management Program, School of Environment, Resources and Development, Asian Institute of Technology, G.P.O. Box 4, Klong Luang, Pathumthani 12120, Thailand, tet@ait.ac.th Y1 - 2004 PY - 2004 DA - 2004 SP - 181 EP - 186 VL - 16 IS - 2 SN - 1001-0742, 1001-0742 KW - man KW - Health & Safety Science Abstracts; Toxicology Abstracts; Pollution Abstracts KW - Bioindicators KW - Chromium KW - Heavy metals KW - Thailand KW - Noise levels KW - Blood levels KW - Public health KW - Factories KW - Urine KW - Occupational exposure KW - X 24166:Environmental impact KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17997731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Sciences+%28China%29&rft.atitle=Health+implication+among+occupational+exposed+workers+in+a+chromium+alloy+factory%2C+Thailand&rft.au=Muttamara%2C+S%3BLeong%2C+ST&rft.aulast=Muttamara&rft.aufirst=S&rft.date=2004-01-01&rft.volume=16&rft.issue=2&rft.spage=181&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Sciences+%28China%29&rft.issn=10010742&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Chromium; Heavy metals; Occupational exposure; Public health; Bioindicators; Factories; Urine; Noise levels; Blood levels; Thailand ER - TY - JOUR T1 - Virulence properties of rough and smooth strains of Vibrio cholerae O1 AN - 17995663; 5935820 AB - A comparative study was carried out to see the differences in pathogenicity of rough and smooth strains. A total of 10 strains including 5 each of rough and smooth strains of Vibrio cholerae O1 were tested and found positive for toxin production by enzyme-linked immunosorbent assay (ELISA) in Richardson's and AKI media. AH the smooth and rough strains, except one, showed a titre of 1:10 and 1:100 in Richardson's and AKI media, respectively. Both types of strains produced enterotoxin in rabbit ileal loop (RIL). The differences in multiplication abilities of smooth and rough strains in RIL were statistically significant (P 0.05) between these properties. This study demonstrated that the rough strains are equally pathogenic and as important as smooth strains. JF - Microbiology and Immunology AU - Islam AU - Ahsan, S AU - Khan, SI AU - Ahmed, Q S AU - Rashid, M H AU - Islam, KMN AU - Sack, R B AD - Environmental Microbiology Laboratory, LSD, ICDDR, B: Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh, sislam@icddrb.org Y1 - 2004 PY - 2004 DA - 2004 SP - 229 EP - 235 VL - 48 IS - 4 SN - 0385-5600, 0385-5600 KW - Microbiology Abstracts B: Bacteriology KW - Virulence KW - Vibrio cholerae KW - Enzyme-linked immunosorbent assay KW - Colonies KW - Phenotypes KW - Toxins KW - J 02822:Biosynthesis and physicochemical properties UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17995663?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Microbiology+and+Immunology&rft.atitle=Virulence+properties+of+rough+and+smooth+strains+of+Vibrio+cholerae+O1&rft.au=Islam%3BAhsan%2C+S%3BKhan%2C+SI%3BAhmed%2C+Q+S%3BRashid%2C+M+H%3BIslam%2C+KMN%3BSack%2C+R+B&rft.aulast=Islam&rft.aufirst=&rft.date=2004-01-01&rft.volume=48&rft.issue=4&rft.spage=229&rft.isbn=&rft.btitle=&rft.title=Microbiology+and+Immunology&rft.issn=03855600&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Vibrio cholerae; Virulence; Colonies; Phenotypes; Toxins; Enzyme-linked immunosorbent assay ER - TY - JOUR T1 - Diarrhoea in Elderly People: Aetiology, and Clinical Characteristics AN - 17960493; 5908841 AB - We examined the characteristics of elderly people attending the Dhaka Hospital of ICDDR,B. The hospital has a diarrhoeal disease surveillance system that enrols a 2% systematic sample of all patients visiting the hospital. We reviewed data of all patients enrolled into the surveillance system (n = 13,782) over the period 1996-2001 to identify patients aged 60 y and above for inclusion into the current study (4% of all surveillance patients; n = 478). V. cholerae O1 was the most common enteric pathogen isolated from faecal culture of the patients (20%), followed by ETEC (13%), Shigella (11%), V. cholerae O139 (10%), Campylobacter jejuni (5%), Salmonella (3%), EPEC (2%), rotavirus (4%), and E. histolytica (2%). The isolation rate of V. cholerae O139 and Shigella was higher among the elderly compared to adults (15-59 y of age, 10% vs 6%, and 11% vs 7% respectively; p < 0.05 for both comparisons). Compared to 15-59-y-olds, a significantly higher proportion of the elderly had visible blood in stools (8% vs 5%), required short-stay ward admission (86% vs 82%) or referral (1% vs < 1%) to a health facility. Early initiation of oral or i.v. rehydration therapy, prompt referral, and immediate clinical diagnosis for assessment of the need for antibiotic therapy might be beneficial for the elderly. JF - Scandinavian Journal of Infectious Diseases AU - Faruque, ASG AU - Malek, MA AU - Khan, AI AU - Huq, S AU - Salam, MA AU - Sack, DA AD - Clinical Sciences Division, ICDDR, B, GPO Box 128, Dhaka 1000, Bangladesh, gfaruque@icddrb.org Y1 - 2004 PY - 2004 DA - 2004 SP - 204 EP - 208 VL - 36 IS - 3 SN - 0036-5548, 0036-5548 KW - man KW - Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Rotavirus KW - Bacteria KW - Age KW - Rehydration KW - Diarrhea KW - Entamoeba histolytica KW - Viruses KW - Shigella KW - Antibiotics KW - Surveillance KW - Vibrio cholerae KW - Amebiasis KW - Feces KW - K 03090:Protozoa: human KW - V 22122:Symptomatology, pathology & etiology KW - J 02846:Gastrointestinal tract UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17960493?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+Journal+of+Infectious+Diseases&rft.atitle=Diarrhoea+in+Elderly+People%3A+Aetiology%2C+and+Clinical+Characteristics&rft.au=Faruque%2C+ASG%3BMalek%2C+MA%3BKhan%2C+AI%3BHuq%2C+S%3BSalam%2C+MA%3BSack%2C+DA&rft.aulast=Faruque&rft.aufirst=ASG&rft.date=2004-01-01&rft.volume=36&rft.issue=3&rft.spage=204&rft.isbn=&rft.btitle=&rft.title=Scandinavian+Journal+of+Infectious+Diseases&rft.issn=00365548&rft_id=info:doi/10.1080%2F00365540410019219 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Amebiasis; Bacteria; Rehydration; Age; Diarrhea; Viruses; Antibiotics; Feces; Surveillance; Rotavirus; Vibrio cholerae; Entamoeba histolytica; Shigella DO - http://dx.doi.org/10.1080/00365540410019219 ER - TY - JOUR T1 - Identification and interrogation of highly informative single nucleotide polymorphism sets defined by bacterial multilocus sequence typing databases AN - 17955219; 5901955 AB - A unified, bioinformatics-driven, single nucleotide polymorphism (SNP)-based approach to microbial genotyping has been developed. Multilocus sequence typing (MLST) databases consist of known variants of standardized housekeeping genes. Normally, seven fragments are defined; a sequence type (ST) consists of the variants of these fragments that are found in a particular isolate. A computer program that can identify highly informative sets of SNPs in entire MLST databases has been constructed. The SNPs either define a particular user-specified ST or provide a high value for Simpson's index of diversity (D), and may thus be generally applicable to that species. SNP sets that are diagnostic for Neisseria meningitidis ST-11 and ST-42, and high-D SNP sets for N. meningitidis and Staphylococcus aureus, were identified and real-time PCR methods to interrogate these SNPs were demonstrated. High-D SNP sets were also identified in other MLST databases. This widely applicable approach allows rapid genetic fingerprinting of infectious agents. JF - Journal of Medical Microbiology AU - Robertson, G A AU - Thiruvenkataswamy, V AU - Shilling, H AU - Price, E P AU - Huygens, F AU - Henskens, F A AU - Giffard, P M AD - Cooperative Research Centre for Diagnostics, Queensland University of Technology (Gardens Point Campus), GPO Box 2434 Brisbane, Queensland 4001, Australia, p.giffard@qut.edu.au Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 35 EP - 45 VL - 53 IS - 1 SN - 0022-2615, 0022-2615 KW - Microbiology Abstracts B: Bacteriology KW - Data banks KW - Fingerprinting KW - Genotyping KW - Polymerase chain reaction KW - Neisseria meningitidis KW - Staphylococcus aureus KW - J 02710:Identification, taxonomy and typing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17955219?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Microbiology&rft.atitle=Identification+and+interrogation+of+highly+informative+single+nucleotide+polymorphism+sets+defined+by+bacterial+multilocus+sequence+typing+databases&rft.au=Robertson%2C+G+A%3BThiruvenkataswamy%2C+V%3BShilling%2C+H%3BPrice%2C+E+P%3BHuygens%2C+F%3BHenskens%2C+F+A%3BGiffard%2C+P+M&rft.aulast=Robertson&rft.aufirst=G&rft.date=2004-01-01&rft.volume=53&rft.issue=1&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Microbiology&rft.issn=00222615&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Neisseria meningitidis; Staphylococcus aureus; Genotyping; Data banks; Polymerase chain reaction; Fingerprinting ER - TY - JOUR T1 - Determination of stress-induced changes in plasma molecular species by two- dimensional correlation Fourier transform infrared spectrometry AN - 17827336; 5873462 AB - For determining exercise-induced changes in plasma molecular species, we investigated the feasibility of using two-dimensional correlation spectra (2D- COS) on 21 series of plasma samples obtained from progressive exercise tests. Intensities of 2D synchronous and asynchronous correlation peaks were compared to concentration evolutions of glucose, lactate, triglycerides (TG), glycerol, fatty acyl moieties, amino acids, proteins, and albumin [determined from plasma Fourier transform infrared (FTIR) spectra] and to performance and training levels of athletes. Synchronous 2D-COS allowed us to determine the linear relationship between protein and fatty acid concentration evolutions as exercise intensity increased ( nu sub(1)- nu sub(2); 2959 vs 1656 and 1543 cm super(-1)). Asynchronous 2D-COS allowed differentiation of fibrinolysis level in subjects during intense exercise, as well as parameters of fatty acid metabolism specifically related either to performance or to training levels. Furthermore, unexpected correlated evolutions of molecular species were highlighted by this method, showing that 2D spectrometry may also be used for experimental investigations on human physiology. This study has demonstrated that 2D-COS may be used for the treatment of complex biological samples, such as plasma. JF - Biopolymers AU - Petibois, C AU - Desbat, B AU - Deleris, G AD - Universite Bordeaux 1, Laboratoire de physico-chimie des molecules, CNRS UMR 5903, 251 Crs. de la Liberation, 33405 Talence, France, cyril.petibois@bioorga.u-bordeaux2.fr Y1 - 2004 PY - 2004 DA - 2004 SP - 696 EP - 704 PB - John Wiley & Sons, Inc., 111 River Street Hoboken NJ 07030 USA, [mailto:custserv@wiley.com], [URL:http://www.wiley.com/] VL - 73 IS - 6 SN - 0006-3525, 0006-3525 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Amino acids KW - Biopolymers KW - Glucose KW - Stress KW - Fibrinolysis KW - Physical training KW - Glycerol KW - I.R. spectroscopy KW - Triglycerides KW - Albumin KW - Lactic acid KW - Fatty acids KW - W4 130:General Biomedical Engineering: Tools & Techniques KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17827336?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biopolymers&rft.atitle=Determination+of+stress-induced+changes+in+plasma+molecular+species+by+two-+dimensional+correlation+Fourier+transform+infrared+spectrometry&rft.au=Petibois%2C+C%3BDesbat%2C+B%3BDeleris%2C+G&rft.aulast=Petibois&rft.aufirst=C&rft.date=2004-01-01&rft.volume=73&rft.issue=6&rft.spage=696&rft.isbn=&rft.btitle=&rft.title=Biopolymers&rft.issn=00063525&rft_id=info:doi/10.1002%2Fbip.20002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Physical training; Fatty acids; I.R. spectroscopy; Stress; Amino acids; Glucose; Glycerol; Fibrinolysis; Biopolymers; Albumin; Triglycerides; Lactic acid DO - http://dx.doi.org/10.1002/bip.20002 ER - TY - JOUR T1 - Tissue Degradation and Enzymatic Activity Observed During Protoplast Isolation in Two Ornamental Grevillea Species AN - 17767243; 5923495 AB - Degradative changes in tissue during protoplast isolation were a contributing factor to low protoplast yields in the salt-sensitive Grevillea arenaria (R. Brown) and the salt-tolerant Grevillea ilicifolia (R. Brown). Protein and malondialdehyde content decreased significantly during the protoplast isolation procedure. Acid and neutral proteases were identified, and high acid protease activities were correlated to low protoplast yields. Acid phosphatase, catalase, polyphenol oxidase and lipoxygenase activities increased in both Grevillea species with cell wall digestion. High activities of catalase and low levels of polyphenol oxidase were correlated with high protoplast yields. Levels of acid phosphatase and lipoxygenase were not good indicators of final protoplast yields. The addition of the anti-oxidant, reduced glutathione, and the acid protease inhibitor, pepstatin A, significantly increased protoplast yields. Strategies were identified to minimize deleterious degradative effects during the isolation of protoplasts, including strict pH control, testing a number of cell wall digestion enzymes, and the addition of anti-oxidative metabolites and protease inhibitors. JF - In Vitro Cellular & Developmental Biology - Plant AU - Kennedy, B F AU - De filippis, LF AD - Department of Applied Biology and Biotechnology, RMIT University, G.P.O. Box 2476V, Melbourne, VIC 3001, Australia, DeFilippis@uts.edu.au Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 119 EP - 125 PB - Society for In Vitro Biology VL - 40 IS - 1 SN - 1054-5476, 1054-5476 KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - Ornamental plants KW - Polyphenols KW - Glutathione KW - Grevillea ilicifolia KW - Proteinase inhibitors KW - Lipoxygenase KW - Acid phosphatase KW - Catalase KW - Digestion KW - Grevillea arenaria KW - Protoplasts KW - Malondialdehyde KW - Cell walls KW - W 30965:Miscellaneous, Reviews KW - W2 32220:Cell culture UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17767243?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=In+Vitro+Cellular+%26+Developmental+Biology+-+Plant&rft.atitle=Tissue+Degradation+and+Enzymatic+Activity+Observed+During+Protoplast+Isolation+in+Two+Ornamental+Grevillea+Species&rft.au=Kennedy%2C+B+F%3BDe+filippis%2C+LF&rft.aulast=Kennedy&rft.aufirst=B&rft.date=2004-01-01&rft.volume=40&rft.issue=1&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=In+Vitro+Cellular+%26+Developmental+Biology+-+Plant&rft.issn=10545476&rft_id=info:doi/10.1043%2F1054-5476%282004%29040%280119%3ATDAEAO%292.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=1054-5476&volume=40&page=119 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Grevillea ilicifolia; Grevillea arenaria; Protoplasts; Polyphenols; Cell walls; Catalase; Acid phosphatase; Digestion; Proteinase inhibitors; Lipoxygenase; Malondialdehyde; Glutathione; Ornamental plants DO - http://dx.doi.org/10.1043/1054-5476(2004)040(0119:TDAEAO)2.0.CO;2 ER - TY - JOUR T1 - Combat between large derived societies: A subterranean army ant established as a predator of mature leaf-cutting ant colonies AN - 17720234; 6109486 AB - Mature colonies of Atta leaf-cutting ants are dominant herbivores throughout the Neotropics. Although young colonies have natural enemies, mature colonies, which live in extensive nests containing millions of workers, currently have no recognised predators. New World army ants (Ecitoninae) are specialist social predators of other ants, and the army ant Nomamyrmex esenbeckii, a primarily subterranean species, is known to prey upon young Atta colonies. Here we present the results of the first long-term study of the predator-prey interaction between N. esenbeckii and Atta. Our study establishes the army ant N. esenbeckii as the only known predator capable of successfully attacking and killing mature as well as young colonies of Atta leaf-cutting ants. In natural raids, and experimental tests, Atta rapidly recruited their largest workers (majors) as a specific defensive response to N. esenbeckii raiders and both taxa used their largest individuals in the frontline of battles. The deployment and behaviour of these large workers demonstrates a size-related division of labour and agrees with the predictions of Lanchester's Linear Law of Combat. Both taxa also used cooperative combat `teams' to overwhelm large combatants from the other side. The success of N. esenbeckii raids varied greatly, such that they were prevented from entering Atta nests in the least successful raids, and completely overran Atta colonies in the most successful raids. The speed and magnitude of the defensive response of mature Atta colonies was key in determining the level of success of N. esenbeckii raids. JF - Insectes Sociaux AU - Powell, S AU - Clark, E AD - School of Biological Sciences, Flinders University, GPO Box 2100, Adelaide, South Australia 5001, Australia, clarkellie@yahoo.com.au Y1 - 2004 PY - 2004 DA - 2004 SP - 342 EP - 351 VL - 51 IS - 4 SN - 0020-1812, 0020-1812 KW - Hymenoptera KW - Ants KW - Entomology Abstracts; Ecology Abstracts; Animal Behavior Abstracts KW - Social organization KW - Formicidae KW - Nomamyrmex esenbeckii KW - Atta KW - Aggressive behavior KW - Predator-prey interactions KW - Herbivores KW - Tropical environment KW - Z 05208:Social entomology KW - D 04659:Insects KW - Y 25503:Insects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17720234?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Insectes+Sociaux&rft.atitle=Combat+between+large+derived+societies%3A+A+subterranean+army+ant+established+as+a+predator+of+mature+leaf-cutting+ant+colonies&rft.au=Powell%2C+S%3BClark%2C+E&rft.aulast=Powell&rft.aufirst=S&rft.date=2004-01-01&rft.volume=51&rft.issue=4&rft.spage=342&rft.isbn=&rft.btitle=&rft.title=Insectes+Sociaux&rft.issn=00201812&rft_id=info:doi/10.1007%2Fs00040-004-0752-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Nomamyrmex esenbeckii; Formicidae; Atta; Predator-prey interactions; Aggressive behavior; Social organization; Herbivores; Tropical environment DO - http://dx.doi.org/10.1007/s00040-004-0752-2 ER - TY - JOUR T1 - Associations between first encounters and ensuing social relations within dyads of two species of lacertid lizards AN - 17539243; 6402945 AB - Researchers often presume that dominant individuals, during an initial series of social interactions, ultimately gain possession of the territory, but detailed studies of the process of social relation establishment in animals are rare. We used an experimental approach on pairs of conspecific newborns of two lizard species (Podarcis sicula and P. melisellensis) to examine whether the outcomes of first encounters are consistent with the formation of social relations during the ensuing three weeks. A major objective was to determine whether social relations expressed during prolonged cohabitation induced divergence of individual growth rates within a dyad. Moreover, we explored to what extent individual differences in growth rate and behavior during social cohabitation paralleled differences expressed when the animals were housed in isolation. Differential expression of behavior within dyads was examined by calculating the difference between values for the two individual lizards. During brief first encounters, access to a localized basking site was determined by agonistic interactions between lizards. Cohabitation of two lizards during prolonged encounters resulted in differences in their thermal microhabitat usage, which in turn induced divergence of their growth rates. The direction and magnitude of the differences in thermal microhabitat use and the divergence in growth rates during prolonged encounters mirrored differences in the interactions exhibited during the first encounter. Moreover, differences between two lizards in initial social interactions, and in thermal microhabitat use and growth rate during prolonged encounters, paralleled differences in thermal microhabitat use exhibited when lizards were housed alone. Thus, it may be possible to predict the outcome of social interactions within dyads based on the differential expression of traits between two lizards housed in isolation. JF - Behavioral Ecology AU - Downes, S AU - Bauwens, D AD - CSIRO Entomotology, GPO Box 1700, Canberra ACT 2601, Australia, sharon.downes@csiro.au Y1 - 2004 PY - 2004 DA - 2004 SP - 938 EP - 945 VL - 15 IS - 6 SN - 1045-2249, 1045-2249 KW - Animal Behavior Abstracts; Ecology Abstracts KW - Growth rate KW - Territory KW - Thermoregulatory behavior KW - Lacertilia KW - Social interactions KW - Social behavior KW - Microenvironments KW - Habitat utilization KW - Neonates KW - Podarcis sicula KW - Y 25504:Vertebrates (excluding fish, birds & mammals) KW - D 04670:Reptiles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17539243?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Behavioral+Ecology&rft.atitle=Associations+between+first+encounters+and+ensuing+social+relations+within+dyads+of+two+species+of+lacertid+lizards&rft.au=Downes%2C+S%3BBauwens%2C+D&rft.aulast=Downes&rft.aufirst=S&rft.date=2004-01-01&rft.volume=15&rft.issue=6&rft.spage=938&rft.isbn=&rft.btitle=&rft.title=Behavioral+Ecology&rft.issn=10452249&rft_id=info:doi/10.1093%2Fbeheco%2Farh090 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Lacertilia; Podarcis sicula; Growth rate; Microenvironments; Social interactions; Habitat utilization; Neonates; Social behavior; Territory; Thermoregulatory behavior DO - http://dx.doi.org/10.1093/beheco/arh090 ER - TY - BOOK T1 - The Department of Homeland Security: Background and challenges AN - 17501347; 6398624 AB - This presentation is divided into two parts. It begins with background on creation of the Department of Homeland Security (DHS) and addresses the issue of how and why this new department came to be. It then focuses on policy issues and challenges facing the new department. JF - TERRORISM: REDUCING VULNERABILITIES AND IMPROVING RESPONSES. AU - Perl, R Y1 - 2004 PY - 2004 DA - 2004 PB - National Academies Press, 2101 Constitution Avenue, NW Washington DC 20418 USA, [URL:http://www.nap.edu] KW - Department of Homeland Security KW - Risk Abstracts KW - terrorism KW - USA KW - Government policies KW - Emergency preparedness KW - security KW - R2 23090:Policy and planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17501347?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Risk+Abstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Perl%2C+R&rft.aulast=Perl&rft.aufirst=R&rft.date=2004-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=The+Department+of+Homeland+Security%3A+Background+and+challenges&rft.title=The+Department+of+Homeland+Security%3A+Background+and+challenges&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Reconciling the policy goals of full employment and ecological sustainability AN - 17411435; 6525569 AB - Ecological economists believe that the growth in real Gross Domestic Product (GDP) is ecologically unsustainable. They have subsequently called for a transitional shift to a steady-state economy. The dilemma that ecological economists face in trying to promote ecological sustainability is its potential employment implications. This paper outlines some policy initiatives to reconcile the conflict between the sustainability and full employment objectives. They include: policies aimed specifically at severing the GDP- employment link; judicious combination of supply-side and demand-side solutions; ecological tax reform a revenue-neutral tax package involving a reduction in taxes on such ''goods'' as labour, income, wages and profits and an increase in taxes and charges on such ''bads'' as resource depletion and pollution; a job guarantee to absorb all remaining unemployed workers; and in view of the constraints that a steady-state economy imposes on demand-side solutions, such as the Job Guarantee, a Basic Income to remunerate non-paid household and volunteer work. Set at something less than a living wage, the Basic Income encourages workers to reduce their hours of employment or exit the labour force altogether. JF - International Journal of Environment, Workplace and Employment AU - Lawn, Philip AD - Flinders University of South Australia, GPO Box 2100, Adelaide, SA 5001 Australia, phil.lawn@flinders.edu.au Y1 - 2004 PY - 2004 DA - 2004 SP - 62 EP - 81 PB - Inderscience Publishers, PO Box 735 Olney Bucks MK46 5WB UK, [mailto:ijnd@inderscience.com], [URL:http://www.inderscience.com] VL - 1 IS - 1 SN - 1741-8437, 1741-8437 KW - Sustainability Science Abstracts KW - Article No. 5604 KW - ecological sustainability KW - full employment KW - ecological tax reform KW - job guarantee KW - basic income KW - ecological economics. KW - Taxation KW - conflicts KW - households KW - income KW - Economics KW - sustainability KW - resource depletion KW - profits KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17411435?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Environment%2C+Workplace+and+Employment&rft.atitle=Reconciling+the+policy+goals+of+full+employment+and+ecological+sustainability&rft.au=Lawn%2C+Philip&rft.aulast=Lawn&rft.aufirst=Philip&rft.date=2004-01-01&rft.volume=1&rft.issue=1&rft.spage=62&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Environment%2C+Workplace+and+Employment&rft.issn=17418437&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - conflicts; Taxation; households; income; Economics; sustainability; resource depletion; profits ER - TY - JOUR T1 - Environment, workplace, and employment: an introduction AN - 17403896; 6525566 AB - A potential conflict has emerged between the desire to achieve ecological sustainability on the one hand and full employment on the other. The conflict exists because of the incongruent prescriptions being advised to resolve both problems a reduced, if not zero, growth rate in the case of ecological sustainability, and a high growth rate in the case of full employment. Very little work has been undertaken to address this crucial issue and no forum specifically exists to deal with it. That is, until now, with the establishment of IJEWE. Its foremost aim is to reconcile the potential conflict between the sustainability and full employment objectives and to find ways to establish sustainable, equitable, and efficient economies. In dealing with this conflict, many other issues emerge namely, the impact of the sustainability objective on industry structure, on forms of employment, on skills formation, on the workplace and workplace relations, on the development of ''green'' technologies, on competitive advantage, and on corporate management strategies. Addressing these issues is a secondary but no less important aim of IJEWE. But all the above issues need to be tackled on the understanding that economic systems are subsystems of the natural environment upon which they depend; that systems of all types are subject to various physical laws and coevolutionary principles; and human well-being is dependent upon the adequate satisfaction of lower- and higher-order needs. JF - International Journal of Environment, Workplace and Employment AU - Lawn, Philip AD - University of South Australia, GPO Box 2100, Adelaide, SA 5001, Australia, phil.lawn@flinders.edu.au Y1 - 2004 PY - 2004 DA - 2004 SP - 4 EP - 39 PB - Inderscience Publishers, PO Box 735 Olney Bucks MK46 5WB UK, [mailto:ijnd@inderscience.com], [URL:http://www.inderscience.com] VL - 1 IS - 1 SN - 1741-8437, 1741-8437 KW - Sustainability Science Abstracts KW - Article No. 5601 KW - ecological sustainability KW - steady-state economy KW - full employment KW - technological progress KW - green technologies KW - skills formation KW - workplace relations KW - competitive advantage KW - corporate management strategies. KW - conflicts KW - Growth rate KW - Economics KW - sustainability KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17403896?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Environment%2C+Workplace+and+Employment&rft.atitle=Environment%2C+workplace%2C+and+employment%3A+an+introduction&rft.au=Lawn%2C+Philip&rft.aulast=Lawn&rft.aufirst=Philip&rft.date=2004-01-01&rft.volume=1&rft.issue=1&rft.spage=4&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Environment%2C+Workplace+and+Employment&rft.issn=17418437&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Growth rate; conflicts; Economics; sustainability ER - TY - JOUR T1 - How well are resource prices likely to serve as indicators of natural resource scarcity? AN - 17402010; 6525758 AB - It is generally believed that when a resource becomes increasingly scarce, a shadow is automatically cast in the form of a higher market price. The higher price induces substitution towards more abundant resources and the development of resource-saving technological progress. A growing number of ecological economists argue that, while resource prices adequately reflect the relative scarcity of various resource types, they are unable to reflect the absolute scarcity of either a particular resource type or the entire stock of all resources. They therefore believe resource prices cannot be used as a basis for determining the sustainable rate of resource use. In support of this emerging ecological economic position, a resource depletion model is employed under specific conditions to show that, for some considerable period of time, the price of a resource can fall even as the stock of the resource declines. Furthermore, the extent of the fall is greater if both a higher discount rate is applied and the marginal cost of resource extraction is assumed to be a function of past resource prices a reasonable assumption given that the resource extraction process requires the use of previously extracted resources. JF - International Journal of Sustainable Development AU - Lawn, Philip AD - School of Economics, Flinders University of South Australia, G.P.O. Box 2100, Adelaide, South Australia 5001, Australia, phil.lawn@flinders.edu.au Y1 - 2004 PY - 2004 DA - 2004 SP - 369 EP - 397 PB - Inderscience Publishers, PO Box 735 Olney Bucks MK46 5WB UK, [mailto:ijnd@inderscience.com], [URL:http://www.inderscience.com] VL - 7 IS - 4 SN - 0960-1406, 0960-1406 KW - Pollution Abstracts; Sustainability Science Abstracts KW - Article No. 6416 KW - absolute scarcity KW - relative scarcity KW - resource prices KW - sustainability KW - sustainable development KW - natural resources KW - ecological economics KW - resource use KW - resource depletion model. KW - Natural resources KW - Economics KW - Sustainable development KW - P 9000:ENVIRONMENTAL ACTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17402010?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Sustainable+Development&rft.atitle=How+well+are+resource+prices+likely+to+serve+as+indicators+of+natural+resource+scarcity%3F&rft.au=Lawn%2C+Philip&rft.aulast=Lawn&rft.aufirst=Philip&rft.date=2004-01-01&rft.volume=7&rft.issue=4&rft.spage=369&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Sustainable+Development&rft.issn=09601406&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Natural resources; Economics; Sustainable development ER - TY - JOUR T1 - The face of forestry research in developing countries: The case of Nepal AN - 17332804; 6248588 AB - Forestry research is needed in the development and management or the forest resources in developing countries. However, in most such countries it has failed to provide the information needed by stakeholders and respond to the problems of sustainable forest development. A case study from Nepal suggests that government's low priority for a forest research policy, lack of a vision for research, lack of funds, weak research planning and management, lack of a monitoring and evaluation system, and low motivation among professionals are the main constraints on forestry research. The current level of support to young researchers is inadequate for their professional development. The paper draws attention to these problems as a means of stimulating debate to alleviate this tragic situation. JF - Forests, Trees and Livelihoods AU - Acharya, K P AD - GPO Box 9136, Kathmandu, Nepal, kpacharya1@hotmail.com Y1 - 2004 PY - 2004 DA - 2004 SP - 41 EP - 53 VL - 15 IS - 1 SN - 1472-8028, 1472-8028 KW - Sustainability Science Abstracts KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17332804?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forests%2C+Trees+and+Livelihoods&rft.atitle=The+face+of+forestry+research+in+developing+countries%3A+The+case+of+Nepal&rft.au=Acharya%2C+K+P&rft.aulast=Acharya&rft.aufirst=K&rft.date=2004-01-01&rft.volume=15&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Forests%2C+Trees+and+Livelihoods&rft.issn=14728028&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Estimations of vapour pressure deficit and crop water demand in APSIM and their implications for prediction of crop yield, water use, and deep drainage AN - 17326166; 6227403 AB - Vapour pressure deficit (VPD) has a significant effect on the amount of water required by the crop to maintain optimal growth. Data required to calculate the mean VPD on a daily basis are rarely available, and most models use approximations to estimate it. In APSIM (Agricultural Production Systems Simulator), VPD is estimated from daily maximum and minimum temperatures with the assumption that the minimum temperature equals dew point, and there is little change in vapour pressure or dew point during any one day. The accuracy of such VPD estimations was assessed using data collected every 15 min near Wagga Wagga in New South Wales, Australia. Actual vapour pressure of the air ranged from 0.5 to 2.5 kPa. For more than 75% of the time its variation was less than 20%, and the maximum variation was up to 50%. Daytime mean VPD ranged from 0 to 5.3 kPa. Daily minimum temperature was found to be a poor estimate of dew point temperature, being higher than dew point in summer and lower in winter. Thus the prediction of vapour pressure was poor. Vapour pressure at 0900 hours was a better estimate of daily mean vapour pressure. Despite the poor estimation of vapour pressure, daytime mean VPD was predicted reasonably well using daily maximum and minimum temperatures. If the vapour pressure at 0900 hours from the SILO Patched Point Dataset was used as the actual daily mean vapour pressure, the accuracy of daytime VPD estimation was further improved. Simulations using historical weather data for 1957-2002 show that such improved accuracy in daytime VPD estimation slightly increased simulated crop yield and deep drainage, while slightly reducing crop water uptake. Comparison of the APSIM RUE/TE and CERES-Wheat approaches for modelling potential transpiration revealed differences in crop water demand estimated by the two approaches. Although the differences had a small effect on the probability distribution of simulated long-term wheat yield, water uptake, and deep drainage, this finding highlights the need for a scientific re-appraisal of the APSIM RUE/TE and energy balance approaches for the estimation of crop demand, which will have implications for modelling crop growth under water-limited conditions and calculation of water required to maintain maximum growth. JF - Australian Journal of Agricultural Research AU - Wang, E AU - Smith, C J AU - Bond, W J AU - Verbuerg, K AD - CSIRO Land and Water, GPO Box 1666, Canberra, ACT 2601, Australia, Enli.Wang@csiro.au Y1 - 2004 PY - 2004 DA - 2004 SP - 1227 EP - 1240 VL - 55 IS - 12 SN - 0004-9409, 0004-9409 KW - Water Resources Abstracts KW - SW 4020:Evaluation process UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17326166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Agricultural+Research&rft.atitle=Estimations+of+vapour+pressure+deficit+and+crop+water+demand+in+APSIM+and+their+implications+for+prediction+of+crop+yield%2C+water+use%2C+and+deep+drainage&rft.au=Wang%2C+E%3BSmith%2C+C+J%3BBond%2C+W+J%3BVerbuerg%2C+K&rft.aulast=Wang&rft.aufirst=E&rft.date=2004-01-01&rft.volume=55&rft.issue=12&rft.spage=1227&rft.isbn=&rft.btitle=&rft.title=Australian+Journal+of+Agricultural+Research&rft.issn=00049409&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - The sustainable development concept and indicators: an introductory essay AN - 17306483; 6134050 AB - While there has been considerable talk about how to achieve sustainable development (SD), there has been much less discussion about whether nations have been successful in moving towards the SD goal. This is due, in part, to the haste with which many SD indicators have been devised and the lack of a commitment on the part of the proponents of SD indicators to determine their worthiness, in particular, their policy-guiding value. A concrete representation of the socio-economic process is put forward as a means to establishing both broad and narrow definitions of SD - the latter required to facilitate the emergence of operational rules of thumb that can serve as the basis for a congruent set of SD indicators. Many of the currently existing SD indicators are analysed in uhis paper within this context. Despite each indicator possessing inherent deficiencies, they can, especially when examined collectively rather than individually, provide important information to policy-makers about past and present activities. Nevertheless, the policy-guiding value of SD indicators depends very much upon their continuous improvement and, where necessary, the rejection of unworthy indicators. JF - International Journal of Environment and Sustainable Development AU - Lawn, P AD - School of Business Economics, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia, phil.lawn@flinders.edu.au Y1 - 2004 PY - 2004 DA - 2004 SP - 199 EP - 234 VL - 3 IS - 3-4 SN - 1474-6778, 1474-6778 KW - Sustainability Science Abstracts KW - Decision making KW - Socio-economic aspects KW - Development policy KW - Social values KW - Indicators KW - Sustainable development KW - M3 1020:Measuring Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17306483?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Environment+and+Sustainable+Development&rft.atitle=The+sustainable+development+concept+and+indicators%3A+an+introductory+essay&rft.au=Lawn%2C+P&rft.aulast=Lawn&rft.aufirst=P&rft.date=2004-01-01&rft.volume=3&rft.issue=3-4&rft.spage=199&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Environment+and+Sustainable+Development&rft.issn=14746778&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Socio-economic aspects; Decision making; Development policy; Social values; Indicators; Sustainable development ER - TY - JOUR T1 - Inferring a biopolitical consensus view of stochastic dynamics for management of a transboundary fishery AN - 17304329; 6139449 AB - Management of trans-boundary fisheries is a complicated problem with biological, legal, economic and political implications. We propose a simple stochastic differential-equation model to describe a biopolitical consensus view of fish stock dynamics. Estimates of the drift and diffusion terms of three stochastic differential equations are obtained using data from the southern bluefin tuna (SBT) fishery with a method based on the Kolmogorov-Smirnov statistic. We refer to these estimated equations as alternative biopolitical consensus views of SBT stock dynamics. Each of these is used to generate a time series of optimal harvest that achieves the objective of maximizing the present value of expected fishery returns. These time series of optimal harvests are then compared to actual harvests for the period 1981-1997. JF - Natural Resource Modeling AU - McDonald, AD AU - Sandal, L K AU - Little, L R AU - Lund, A-C AU - Steinshamn, S-I AD - CSIRO Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, David.McDonald@csiro.au Y1 - 2004 PY - 2004 DA - 2004 SP - 467 EP - 487 VL - 17 IS - 4 SN - 0890-8575, 0890-8575 KW - Albacores KW - Southern bluefin tuna KW - Oceanic Abstracts; Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Marine KW - Q1 01604:Stock assessment and management KW - D 04003:Modeling, mathematics, computer applications KW - M3 1130:Water KW - O 5020:Fisheries and Fishery Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17304329?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Natural+Resource+Modeling&rft.atitle=Inferring+a+biopolitical+consensus+view+of+stochastic+dynamics+for+management+of+a+transboundary+fishery&rft.au=McDonald%2C+AD%3BSandal%2C+L+K%3BLittle%2C+L+R%3BLund%2C+A-C%3BSteinshamn%2C+S-I&rft.aulast=McDonald&rft.aufirst=AD&rft.date=2004-01-01&rft.volume=17&rft.issue=4&rft.spage=467&rft.isbn=&rft.btitle=&rft.title=Natural+Resource+Modeling&rft.issn=08908575&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Marine ER - TY - JOUR T1 - Metals in airborne particulate matter in the industrial district of Santa Cruz, Rio de Janeiro, in an annual period AN - 17284156; 5890977 AB - The main goal of this work is to assess the concentrations of total suspended particles (TSP) and airborne particulate trace metals in the Industrial District of Santa Cruz, Rio de Janeiro, Brazil, where the main pollution sources are the local industries. The sampling was performed using a high-volume pump. The TSP levels were determined by gravimetry and the metals by inductively coupled plasma atomic emission. A geometrical mean of 87+/-40 mu g m super(-3) was determined for TSP for the period March 2001-February 2002, which is higher than both the Brazilian primary and secondary standards of air quality. Metals concentrations were compared with literature values for other regions of the world and with air quality standards of regulatory agencies. Mn, Fe, Zn, Cu, Cr and Al levels are higher than the reported values for other industrial and urban areas around the world. Mn, Cr and Ni concentrations are higher than the US-EPA standards. Cluster and principal component analysis were used to get some insight about the sources of metals and the correlations among them. JF - Atmospheric Environment AU - Quiterio, S L AU - Da Silva, CRS AU - Arbilla, G AU - Escaleira, V AD - Departamento de Fisico Quimica, Instituto de Quimica, Universitaria Federal do Rio de Janeiro, CT, Bloco A, Sala 408, Cidade Universitaria, Rio de Janeiro, RJ 21949-900, Brazil, graciela@iq.ufrj.br Y1 - 2004/01// PY - 2004 DA - January 2004 SP - 321 EP - 331 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 38 IS - 2 SN - 1352-2310, 1352-2310 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Airborne particulate matter KW - Trace metals KW - Industrial sources KW - Principal component analysis KW - Rivers KW - Atmospheric pollution sources KW - Brazil, Rio de Janeiro, Santa Cruz Dist. KW - Gravimetry KW - Air quality KW - Correlation analysis KW - Suspended particulate matter KW - Freshwater KW - Air quality standards KW - Brazil, Rio de Janeiro KW - Particulate matter in atmosphere KW - Industrial wastes KW - Governments KW - Industrial areas KW - Metals in atmosphere KW - Industrial atmospheric pollution KW - USA, California, Santa Cruz KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - Q2 09241:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17284156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Metals+in+airborne+particulate+matter+in+the+industrial+district+of+Santa+Cruz%2C+Rio+de+Janeiro%2C+in+an+annual+period&rft.au=Quiterio%2C+S+L%3BDa+Silva%2C+CRS%3BArbilla%2C+G%3BEscaleira%2C+V&rft.aulast=Quiterio&rft.aufirst=S&rft.date=2004-01-01&rft.volume=38&rft.issue=2&rft.spage=321&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2003.09.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Rivers; Industrial wastes; Gravimetry; Governments; Suspended particulate matter; Trace metals; Atmospheric pollution sources; Particulate matter in atmosphere; Air quality; Correlation analysis; Metals in atmosphere; Industrial atmospheric pollution; Air quality standards; Industrial areas; Brazil, Rio de Janeiro; Brazil, Rio de Janeiro, Santa Cruz Dist.; USA, California, Santa Cruz; Freshwater DO - http://dx.doi.org/10.1016/j.atmosenv.2003.09.017 ER - TY - JOUR T1 - A global protocol for monitoring of coral bleaching AN - 17133751; 6781672 AB - Coral bleaching and subsequent mortality represent a major threat to the future health and productivity of coral reefs. However a lack of reliable data on occurrence, severity and other characteristics of bleaching events hampers research on the causes and consequences of this important phenomenon. This article describes a global protocol for monitoring coral bleaching events, which addresses this problem and can be used by people with different levels of expertise and resources. JF - NAGA AU - Oliver, J AU - Setiasin, N AU - Marshall, P AU - Hansen, L AD - The WorldFish Center, PO Box 500, GPO, 10670 Penang Malaysia, j.oliver@cgiar.org Y1 - 2004 PY - 2004 DA - 2004 SP - 49 EP - 53 VL - 27 IS - 1-2 SN - 1511-8533, 1511-8533 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Marine KW - Mortality KW - Resource management KW - Bleaching KW - Coral reefs KW - Monitoring KW - Q1 08463:Habitat community studies KW - Q5 08504:Effects on organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17133751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=NAGA&rft.atitle=A+global+protocol+for+monitoring+of+coral+bleaching&rft.au=Oliver%2C+J%3BSetiasin%2C+N%3BMarshall%2C+P%3BHansen%2C+L&rft.aulast=Oliver&rft.aufirst=J&rft.date=2004-01-01&rft.volume=27&rft.issue=1-2&rft.spage=49&rft.isbn=&rft.btitle=&rft.title=NAGA&rft.issn=15118533&rft_id=info:doi/ L2 - http://www.worldfishcenter.org/naga/naga27-1n2/pdf/article-09.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-04-01 N1 - SuppNotes - Physical medium: Printed matter, Internet; http://www.worldfishcenter.org/naga/naga27-1n2/pdf/article-09.pdf N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Mortality; Resource management; Bleaching; Coral reefs; Monitoring; Marine ER - TY - JOUR T1 - Uranium mine rehabilitation: the story of the South Alligator Valley intervention AN - 16175705; 5970718 AB - The rehabilitation of radioactively contaminated sites is an activity generally regarded with suspicion by the community. This is certainly the case for Australian Aboriginal traditional landowners. This paper describes the historical background to, and the successful development and implementation of, a consultation and planning process to rehabilitate former uranium mining and milling facilities on Aboriginal lands of the World Heritage-listed Kakadu National Park in northern Australia. The process of developing an appropriate community communication and consultation process to allay concerns about radioactivity is a cornerstone of the rehabilitation program. The initial stages of the program's implementation are also described. This program is also the first example of a radiological intervention under modern environmental and radiation protection legislation in the region. It was necessary to develop radiological standards for use in the program as none had been promulgated under existing relevant legislation. JF - Journal of Environmental Radioactivity AU - Waggitt, P W AD - Department of the Environment and Heritage, Office of the Supervising Scientist, GPO Box 461, Darwin, NT 0801, Australia, peter.waggitt@deh.gov.au Y1 - 2004 PY - 2004 DA - 2004 SP - 51 EP - 66 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 76 IS - 1-2 SN - 0265-931X, 0265-931X KW - Pollution Abstracts KW - Uranium mining KW - Rehabilitation KW - Native title KW - Traditional landowners KW - Alligator Rivers Region KW - Radiological intervention KW - Community consultation KW - Radiation standards KW - Uranium KW - Remediation KW - Radioactive pollution KW - Environmental restoration KW - Mining KW - Australia, Northern Terr., Kakadu Natl. Park KW - Legislation KW - P 8000:RADIATION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16175705?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Radioactivity&rft.atitle=Uranium+mine+rehabilitation%3A+the+story+of+the+South+Alligator+Valley+intervention&rft.au=Waggitt%2C+P+W&rft.aulast=Waggitt&rft.aufirst=P&rft.date=2004-01-01&rft.volume=76&rft.issue=1-2&rft.spage=51&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Radioactivity&rft.issn=0265931X&rft_id=info:doi/10.1016%2Fj.jenvrad.2004.03.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2004-09-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Radiation standards; Uranium; Remediation; Environmental restoration; Radioactive pollution; Mining; Legislation; Australia, Northern Terr., Kakadu Natl. Park DO - http://dx.doi.org/10.1016/j.jenvrad.2004.03.018 ER - TY - JOUR T1 - The Value of Home-Based Collection of Biospecimens in Reproductive Epidemiology AN - 14686017; 10656116 AB - One problem in studying the relation between environmental exposures and human health, including subtle markers of human reproduction, is that sample collection can be encumbered by the logistics and expense of obtaining biospecimens from participants. One way to address the issue incorporates home-based collection protocols carried out with minimal to no oversight from study staff. A general overview of the utility of biospecimens is presented, identifying those amenable to home collection, including urine, blood, semen, saliva, breast milk, hair and hair follicles, nails, buccal cells, and vaginal swabs. Each is discussed in terms of what can be measured and methods of collection in the home environment. Limitations to home collection of biospecimens are also highlighted, pertaining to noncompliance, the introduction of error, time to processing, and transport to the laboratory. JF - Environmental Health Perspectives AU - Rockett, John C AU - Buck, Germaine M AU - Lynch, Courtney D AU - Perreault, Sally D Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 94 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - SEMEN KW - BIOLOGICAL INDICATORS KW - BREAST MILK KW - HAIR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14686017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Value+of+Home-Based+Collection+of+Biospecimens+in+Reproductive+Epidemiology&rft.au=Rockett%2C+John+C%3BBuck%2C+Germaine+M%3BLynch%2C+Courtney+D%3BPerreault%2C+Sally+D&rft.aulast=Rockett&rft.aufirst=John&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=94&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; SEMEN; BIOLOGICAL INDICATORS; BREAST MILK; HAIR ER - TY - JOUR T1 - Identification of Sources of Lead in Children in a Primary ZincLead Smelter Environment AN - 14685162; 10656111 AB - In North Lake Macquarie, located approximately 120 km north of Sydney, NSW, Australia, lead isotopic analyses of environmental and biologic samples were used to determine the sources of lead, especially in the teeth of children. A primary zincPb smelter was operated within the community until 2003, and the Pb isotopic data were collected over the period 19912002. Over time, variable numbers of samples were taken from six houses. A brief history is provided of the children in each house. The isotopic measurements demonstrated that the contribution of Pb from paint to tooth and blood Pb levels was minor, except in one child from one of the homes, and the contribution from gasoline Pb was also small. The only credible remaining source was from the smelting activities, and the main pathway of Pb to the children was found to be through ingestion of soil and dust. Based on the isotopic composition of the smelter emissions, approximately 55100% of the Pb in teeth was derived from the smelter. JF - Environmental Health Perspectives AU - Gulson, Brian L AU - Mizon, Karen J AU - Davis, Jeff D AU - Palmer, Jacqueline M AU - Vimpani, Graham Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 52 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SMELTERS KW - SOIL CONTAMINATION KW - RADIOISOTOPIC TRACERS KW - BLOOD LEAD LEVEL KW - SOURCE MEASUREMENT KW - RESPIRABLE DUST KW - AUSTRALIA KW - BIOACCUMULATION, HUMAN KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14685162?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Identification+of+Sources+of+Lead+in+Children+in+a+Primary+Zinc%26lt%3BND%26gt%3BLead+Smelter+Environment&rft.au=Gulson%2C+Brian+L%3BMizon%2C+Karen+J%3BDavis%2C+Jeff+D%3BPalmer%2C+Jacqueline+M%3BVimpani%2C+Graham&rft.aulast=Gulson&rft.aufirst=Brian&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=52&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SMELTERS; SOIL CONTAMINATION; BLOOD LEAD LEVEL; RADIOISOTOPIC TRACERS; SOURCE MEASUREMENT; LEAD; RESPIRABLE DUST; AUSTRALIA; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Biomarkers for Assessing Reproductive Development and Health: Part 1-Pubertal Development AN - 14684966; 10656117 AB - Confusion surrounds the secular trend in growth, which pertains to the phenomena of earlier puberty and increased final height, because puberty is a complex and multifaceted process. The proposed National Children's Study would afford an unprecedented opportunity to study the sensitivity and accuracy of current biomarkers of pubertal development. Here, current and emerging biomarkers of male and female pubertal development are reviewed that could be used in such a longitudinal children's study. Discussed are Tanner scales, which are anatomical markers for staging pubertal development; other physical biomarkers such as skeletal growth, body composition, and fundamental voice frequency; and molecular and cellular biomarkers, including genetic markers, biomarkers of bone growth and mineralization, and hormonal biomarkers of puberty such as Mullerian inhibiting substances, inhibins, leptin, antisperm autoantibodies, and spermaturia. JF - Environmental Health Perspectives AU - Rockett, John C AU - Lynch, Courtney D AU - Buck, Germaine M Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 105 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOLOGICAL INDICATORS KW - REPRODUCTION, HUMAN KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14684966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biomarkers+for+Assessing+Reproductive+Development+and+Health%3A+Part+1-Pubertal+Development&rft.au=Rockett%2C+John+C%3BLynch%2C+Courtney+D%3BBuck%2C+Germaine+M&rft.aulast=Rockett&rft.aufirst=John&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=105&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOLOGICAL INDICATORS; REPRODUCTION, HUMAN; AGE COMPARISONS ER - TY - JOUR T1 - Lead, Arsenic, and Polycyclic Aromatic Hydrocarbons in Soil and House Dust in the Communities Surrounding the Sydney, Nova Scotia, Tar Ponds AN - 14684559; 10656108 AB - Household dust and soil samples were collected in residential communities adjacent to the Sydney, NS, Canada, tar ponds, and concentrations of lead, arsenic, and PAHs were measured. The tar ponds resulted from the release of coal tar produced in coke ovens, which also, along with a steel plant, released tons of particulate matter on the surrounding community. The soil concentrations of Pb, As, and PAHs were found to be similar in the three communities surrounding the tar ponds, but significantly different from those from background locations. The results were consistent with ambient-air levels during the site operation. Dust analysis indicated that the source of Pb and As in the homes originated outside the homes. Spearman correlation analysis revealed that Pb, As, and PAHs were from a common source, and a similar PAH profile was found in entry-way soil, pathway soil, and house dust. JF - Environmental Health Perspectives AU - Lambert, Timothy W AU - Lane, Stephanie Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 35 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SOIL CONTAMINATION KW - SPATIAL COMPARISONS KW - NOVA SCOTIA KW - POLYCYCLIC AROMATIC HYDROCARBON KW - COAL TARS KW - DUST FALL KW - ARSENIC KW - ATMOSPHERIC POLLUTANT DEPOSITION KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14684559?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lead%2C+Arsenic%2C+and+Polycyclic+Aromatic+Hydrocarbons+in+Soil+and+House+Dust+in+the+Communities+Surrounding+the+Sydney%2C+Nova+Scotia%2C+Tar+Ponds&rft.au=Lambert%2C+Timothy+W%3BLane%2C+Stephanie&rft.aulast=Lambert&rft.aufirst=Timothy&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - COAL TARS; SOIL CONTAMINATION; ARSENIC; DUST FALL; SPATIAL COMPARISONS; LEAD; ATMOSPHERIC POLLUTANT DEPOSITION; POLYCYCLIC AROMATIC HYDROCARBON; NOVA SCOTIA ER - TY - JOUR T1 - Closing the Research Loop: a Risk-Based Approach for Communicating Results of Air Pollution Exposure Studies AN - 14684512; 10656107 JF - Environmental Health Perspectives AU - Payne-Sturges, Devon C AU - Schwab, Margo AU - Buckley, Timothy J Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 28 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MARYLAND KW - INFORMATION, ENV KW - PUBLIC PARTICIPATION KW - AIR POLLUTION RESEARCH KW - VOLATILE ORGANIC COMPOUNDS KW - URBAN ATMOSPHERE KW - RISK ASSESSMENT KW - MONITORING, AIR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14684512?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Closing+the+Research+Loop%3A+a+Risk-Based+Approach+for+Communicating+Results+of+Air+Pollution+Exposure+Studies&rft.au=Payne-Sturges%2C+Devon+C%3BSchwab%2C+Margo%3BBuckley%2C+Timothy+J&rft.aulast=Payne-Sturges&rft.aufirst=Devon&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=28&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; MONITORING, AIR; MARYLAND; INFORMATION, ENV; AIR POLLUTION RESEARCH; PUBLIC PARTICIPATION; VOLATILE ORGANIC COMPOUNDS; URBAN ATMOSPHERE ER - TY - JOUR T1 - Off to a Good Start: the Influence of Pre- and Periconceptional Exposures, Parental Fertility, and Nutrition on Children's Health AN - 14683427; 10656113 JF - Environmental Health Perspectives AU - Chapin, Robert E AU - Robbins, Wendie A AU - Schieve, Laura A AU - Sweeney, Anne M AU - Tabacova, Sonia A AU - Tomashek, Kay M Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 69 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEMEN KW - PATHOLOGY, CHILDREN KW - REPRODUCTION, HUMAN KW - FERTILITY KW - BIRTH DEFECTS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14683427?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Off+to+a+Good+Start%3A+the+Influence+of+Pre-+and+Periconceptional+Exposures%2C+Parental+Fertility%2C+and+Nutrition+on+Children%27s+Health&rft.au=Chapin%2C+Robert+E%3BRobbins%2C+Wendie+A%3BSchieve%2C+Laura+A%3BSweeney%2C+Anne+M%3BTabacova%2C+Sonia+A%3BTomashek%2C+Kay+M&rft.aulast=Chapin&rft.aufirst=Robert&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEMEN; PATHOLOGY, CHILDREN; FERTILITY; REPRODUCTION, HUMAN; BIRTH DEFECTS, HUMAN ER - TY - JOUR T1 - Methodologic and Statistical Approaches to Studying Human Fertility and Environmental Exposure AN - 14682841; 10656115 AB - The factors known to affect fertility, including age, environmental exposures, and sexual behavior, are reviewed, and methodologic and statistical issues involved in studying fecundity are discussed. Fecundity refers to a couple's probability of pregnancy with regular intercourse without the use of contraception. The data necessary for such a study include those collected at the level of the couple, the cycle, and each day in the study. The optimal study design for assessing factors related to biological fecundity and sterility, which should focus on time to pregnancy, must begin prior to conception and involve detailed data on the timing of intercourse and ovulation. Analysis of day-specific probabilities of conception relative to ovulation will allow an assessment of environmental and demographic factors on fecundity, independent of sexual behavior. JF - Environmental Health Perspectives AU - Tingen, Candace AU - Stanford, Joseph B AU - Dunson, David B Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 87 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - QUANTITATIVE ANALYSIS KW - REPRODUCTION, HUMAN KW - FERTILITY KW - PREGNANCY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14682841?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Methodologic+and+Statistical+Approaches+to+Studying+Human+Fertility+and+Environmental+Exposure&rft.au=Tingen%2C+Candace%3BStanford%2C+Joseph+B%3BDunson%2C+David+B&rft.aulast=Tingen&rft.aufirst=Candace&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - QUANTITATIVE ANALYSIS; FERTILITY; REPRODUCTION, HUMAN; PREGNANCY ER - TY - JOUR T1 - Relationship of Serum TCDD Concentrations and Age at Exposure of Female Residents of Seveso, Italy AN - 14682835; 10656106 AB - In July 1976, an explosion at a chemical plant in Seveso, Italy, resulted in the release of an aerosol cloud containing sodium hydroxide, ethylene glycol, sodium trichlorophenate, and up to 30 kg of TCDD, causing the highest known residential exposure to TCDD. In this study, stored serum samples were analyzed for TCDD from a sample of the female population residing in the two more-impacted zones, and relationships of serum TCDD concentrations and age at exposure were explored. A fivefold difference in serum TCDD levels was found between females residing in the most-contaminated zone and those residing in the next most-contaminated zone. Children were exposed disproportionately, with the youngest children receiving the greatest exposure. However, higher levels of TCDD were also found in serum pools from young children living in non-exposed areas. The higher body burdens of children explained, in part, their higher frequency of chloracne. The pooled data from the unexposed areas indicated that analytes other than TCDD contributed approximately 80 ppt to the total toxic eqivalence value. JF - Environmental Health Perspectives AU - Eskenazi, Brenda AU - Mocarelli, Paolo AU - Warner, Marcella AU - Needham, Larry AU - Patterson, Donald G AU - Samuels, Steven AU - Turner, Wayman Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 22 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AGE COMPARISONS KW - BIOACCUMULATION, HUMAN KW - TETRACHLORODIBENZODIOXINS KW - BLOOD ANALYSIS KW - CONTAMINATION INCIDENTS KW - ITALY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14682835?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Relationship+of+Serum+TCDD+Concentrations+and+Age+at+Exposure+of+Female+Residents+of+Seveso%2C+Italy&rft.au=Eskenazi%2C+Brenda%3BMocarelli%2C+Paolo%3BWarner%2C+Marcella%3BNeedham%2C+Larry%3BPatterson%2C+Donald+G%3BSamuels%2C+Steven%3BTurner%2C+Wayman&rft.aulast=Eskenazi&rft.aufirst=Brenda&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=22&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; CONTAMINATION INCIDENTS; AGE COMPARISONS; ITALY; BIOACCUMULATION, HUMAN; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Mean Total Arsenic Concentrations in Chicken 19892000 and Estimated Exposures for Consumers of Chicken AN - 14682778; 10656105 AB - Data gleaned from USDA's National Residue Program were used to estimate the concentrations of arsenic in muscle tissue of chicken. The As monitoring measurements from liver tissue samples were used, which were reported at 0, 3, 4, and 5 d after withdrawal from roxarsone in chickens fed 50 ppm for seven weeks. Roxarsone is the most frequently used additive among a group of organic As compounds added to feed of broiler chickens to control coccidial intestinal parasites. The data were then used to calculate As exposure concentrations associated with varying levels of chicken consumption. Results suggested that As concentrations in young chickens could be approximately threefold greater than in other meat and poultry products. The proportion of inorganic and organic As in chicken was estimated at 0.65 and 0.35, respectively. A mean chicken consumption rate of 60 g/d resulted in an intake of 3.625.24 mu g inorganic As/d and 5.578.07 mu g total As/d. While the estimates were below the Joint FAO/WHO Expert Committee on Food Additives tolerable daily intake of 2 mu g/kg/d, chicken consumption accounted for a sizable proportion of the tolerable daily intake. JF - Environmental Health Perspectives AU - Lasky, Tamar AU - Sun, Wenyu AU - Kadry, Abdel AU - Hoffman, Michael K Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 18 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - FOOD CONSUMPTION PATTERNS KW - BIOACCUMULATION, HUMAN KW - FOOD CONTAMINATION KW - ARSENIC KW - FEED ADDITIVES KW - POULTRY PRODUCTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14682778?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Mean+Total+Arsenic+Concentrations+in+Chicken+1989%26lt%3BND%26gt%3B2000+and+Estimated+Exposures+for+Consumers+of+Chicken&rft.au=Lasky%2C+Tamar%3BSun%2C+Wenyu%3BKadry%2C+Abdel%3BHoffman%2C+Michael+K&rft.aulast=Lasky&rft.aufirst=Tamar&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=18&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FOOD CONSUMPTION PATTERNS; FEED ADDITIVES; ARSENIC; POULTRY PRODUCTS; BIOACCUMULATION, HUMAN; FOOD CONTAMINATION ER - TY - JOUR T1 - Prospective Pregnancy Study Designs for Assessing Reproductive and Developmental Toxicants AN - 14682775; 10656114 JF - Environmental Health Perspectives AU - Buck, Germaine M AU - Lynch, Courtney D AU - Stanford, Joseph B AU - Sweeney, Anne M AU - Schieve, Laura A AU - Rockett, John C AU - Selevan, Sherry G Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 79 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DESIGN KW - TOXIC SUBSTANCES KW - TERATOGENIC AGENTS KW - PREGNANCY KW - REPRODUCTION, HUMAN KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14682775?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prospective+Pregnancy+Study+Designs+for+Assessing+Reproductive+and+Developmental+Toxicants&rft.au=Buck%2C+Germaine+M%3BLynch%2C+Courtney+D%3BStanford%2C+Joseph+B%3BSweeney%2C+Anne+M%3BSchieve%2C+Laura+A%3BRockett%2C+John+C%3BSelevan%2C+Sherry+G&rft.aulast=Buck&rft.aufirst=Germaine&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DESIGN; TOXIC SUBSTANCES; TERATOGENIC AGENTS; REPRODUCTION, HUMAN; PREGNANCY; LITERATURE SURVEYS ER - TY - JOUR T1 - Long-Term Neurobehavioral Health Effects of Methyl Parathion Exposure in Children in Mississippi and Ohio AN - 14682438; 10656110 AB - Neurobehavioral development was examined in children exposed subacutely to methyl parathion at doses lower than those observed in occupationally exposed workers. The subjects were selected from files provided to the Agency for Toxic Substances and Disease Registry by health departments in Ohio and Mississippi. Personal interviews were conducted with parents/guardians of the selected children, and performance- and informant-based tests, which are described, were performed. Results revealed that exposure to methyl parathion was not associated with poorer performance on most neurobehavioral tests. However, effects were noted for tasks that involve short-term memory and attention, and parents of exposed children reported that their children had more behavioral and motor skills problems than unexposed children. The data suggested that, when there were neurobehavioral effects from subacute exposure to low levels of methyl parathion, they appeared to be transient in children who were 6 yr old or younger when they were exposed. JF - Environmental Health Perspectives AU - Ruckart, Perri Zeitz AU - Kakolewski, Kirsten AU - Bove, Frank J AU - Kaye, Wendy E Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 46 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - METHYL PARATHION KW - NEUROTOXICITY KW - OHIO KW - BEHAVIOR KW - PATHOLOGY, CHILDREN KW - MISSISSIPPI KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14682438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Long-Term+Neurobehavioral+Health+Effects+of+Methyl+Parathion+Exposure+in+Children+in+Mississippi+and+Ohio&rft.au=Ruckart%2C+Perri+Zeitz%3BKakolewski%2C+Kirsten%3BBove%2C+Frank+J%3BKaye%2C+Wendy+E&rft.aulast=Ruckart&rft.aufirst=Perri&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=46&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - METHYL PARATHION; NEUROTOXICITY; OHIO; PATHOLOGY, CHILDREN; BEHAVIOR; MISSISSIPPI; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Correlation Between Blood Ethylenethiourea and Thyroid Gland Disorders Among Banana Plantation Workers in the Philippines AN - 14682289; 10656109 AB - Blood and urine samples were collected from randomly selected banana plantation workers in The Philippines with at least a 3-yr history of direct or indirect exposure to ethylenebisdithiocarbamate fungicides, and correlations between the levels of the metabolite, ethylenethiourea, and the incidence of thyroid gland disorders were explored. Control samples were also collected from workers at an organic farm who were not exposed to the fungicides. Data were collected on demographics, nutrition, work background, and exposure. Thyroid-stimulating hormone levels were significantly higher in the study group compared with controls, but no correlation was found between the time of exposure and thyroid-stimulating hormone levels. Generally higher levels of urinary ethylenethiourea were found among backpack sprayers with an acute exposure to ethylenebisdithiocarbamates as well as chronic exposure for at least 3 yr. Blood ethylenethiourea levels correlated poorly with urinary levels. After controlling for age and dietary preferences, no significant differences in thyroid function tests were found among the groups, but a higher prevalence of solitary nodules was detected by ultrasound in the exposed workers. JF - Environmental Health Perspectives AU - Panganiban, Lynn AU - Cortes-Maramba, Nelia AU - Dioquino, Carissa AU - Suplido, Maria Lurenda AU - Ho, Herbert AU - Francisco-Rivera, Ana AU - Manglicmot-Yabes, Ailyn Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 42 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PHILIPPINES KW - FUNGICIDE APPLICATION KW - HEALTH SAFETY, OCCUPATIONAL KW - BLOOD ANALYSIS KW - PESTICIDE EXPOSURE KW - THIOCARBAMATES KW - THYROID FUNCTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14682289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correlation+Between+Blood+Ethylenethiourea+and+Thyroid+Gland+Disorders+Among+Banana+Plantation+Workers+in+the+Philippines&rft.au=Panganiban%2C+Lynn%3BCortes-Maramba%2C+Nelia%3BDioquino%2C+Carissa%3BSuplido%2C+Maria+Lurenda%3BHo%2C+Herbert%3BFrancisco-Rivera%2C+Ana%3BManglicmot-Yabes%2C+Ailyn&rft.aulast=Panganiban&rft.aufirst=Lynn&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; BLOOD ANALYSIS; PHILIPPINES; FUNGICIDE APPLICATION; PESTICIDE EXPOSURE; THYROID FUNCTION; THIOCARBAMATES ER - TY - JOUR T1 - A Retrospective Assessment of Mortality from the London Smog Episode of 1952: the Role of Influenza and Pollution AN - 14681732; 10656103 AB - In London, UK, mortality did not return to normal levels for several months after a significant smog episode that occurred in December 1952. To examine the influence of influenza on the extended mortality, the number of deaths from influenza was estimated using two approaches: observations from a general medical practice and analysis of data from a vaccine trial. The data were used to construct an estimate of the influence, and a simple sensitivity analysis was performed to explore how different values for the incidence or case-fatality rate could influence influenza mortality estimates and the fraction of unexplained deaths. In the sensitivity analysis, both the incidence and case-fatality rates were increased for the period through the end of February 1953. Results indicated that the estimated case-fatality and incidence rates for influenza would have to be underestimated drastically for influenza to account for the excess mortality after the smog. Ultimately, a large number of deaths remained unexplained by influenza. JF - Environmental Health Perspectives AU - Bell, Michelle L AU - Davis, Devra L AU - Fletcher, Tony Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 6 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION INCIDENTS KW - SMOG, PHOTOCHEMICAL KW - INFLUENZA KW - DEATH RATES KW - URBAN ATMOSPHERE KW - MORTALITY PATTERNS KW - UNITED KINGDOM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14681732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Retrospective+Assessment+of+Mortality+from+the+London+Smog+Episode+of+1952%3A+the+Role+of+Influenza+and+Pollution&rft.au=Bell%2C+Michelle+L%3BDavis%2C+Devra+L%3BFletcher%2C+Tony&rft.aulast=Bell&rft.aufirst=Michelle&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION INCIDENTS; MORTALITY PATTERNS; SMOG, PHOTOCHEMICAL; INFLUENZA; DEATH RATES; URBAN ATMOSPHERE; UNITED KINGDOM ER - TY - JOUR T1 - Getting the Lead Out" in Hartford, Connecticut: a Multifaceted Lead-Poisoning Awareness Campaign AN - 14681674; 10656102 AB - When it was discovered that Hartford, CT, ranked first in the state for several lead-poisoning risk factors, a Lead Poisoning Prevention and Education Program was established in 1999, aimed at increasing awareness of Pb poisoning and fostering behaviors leading the Pb-poisoning prevention. The multifaceted public-awareness program that was implemented is described, which included an educational video, a children's art display at the state capital, a local hardware-store educational display, newspaper advertisements, billboards, a milk carton campaign, signs on busses and bus shelters, signs on municipal sanitation trucks, an orange-juice carton campaign, and a prevent Pb-poisoning postmark. Results are presented from a questionnaire used to evaluate the success of the campaign, which focused on Pb poisoning knowledge, the reach of the campaign, steps taken to learn about or prevent Pb poisoning, and campaign effectiveness. The most effective component was found to be newspaper advertisements, which prompted respondents to take steps toward preventing Pb poisoning, but the billboards and the signs on busses and bus shelters were also found to be quite effective. JF - Environmental Health Perspectives AU - McLaughlin, Tara AU - Humphries, Owen AU - Nguyen, Tung AU - Maljanian, Rose AU - McCormack, Katherine Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 1 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CONNECTICUT KW - PUBLIC HEALTH KW - EDUCATION, PUBLIC KW - INFORMATION SYSTEMS, ENV KW - LEAD POISONING KW - MEDIA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14681674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=%26lt%3B%22%26gt%3BGetting+the+Lead+Out%22+in+Hartford%2C+Connecticut%3A+a+Multifaceted+Lead-Poisoning+Awareness+Campaign&rft.au=McLaughlin%2C+Tara%3BHumphries%2C+Owen%3BNguyen%2C+Tung%3BMaljanian%2C+Rose%3BMcCormack%2C+Katherine&rft.aulast=McLaughlin&rft.aufirst=Tara&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - INFORMATION SYSTEMS, ENV; CONNECTICUT; LEAD POISONING; MEDIA; PUBLIC HEALTH; EDUCATION, PUBLIC ER - TY - JOUR T1 - Proximity of California Public Schools to Busy Roads AN - 14681649; 10656112 AB - The characteristics of public schools in California were examined in terms of their proximity to busy roads, taking into account race/ethnicity and socioeconomic status. In total, 7515 schools were examined by compiling demographic, social, economic, housing, and population density data. Geographic information system software was used to identify the addresses and to determine the distances from each school to all road segments within a 150-m buffer around the school. Most schools close to high traffic volume were in large urban areas, but several schools in small urban and rural areas were also close to busy roads. As the traffic exposure category increased, the percentages of Hispanic and of non-Hispanic black children attending also increased. Economic disadvantage was also related to traffic exposure, and the median percentage of children whose primary language was not English and who had been assessed to lack English language skills rose steadily with increasing traffic. Regression analysis revealed that population density/mi super(2) in the surrounding census tract was the strongest predictor of traffic category, but all measures of low socioeconomic status were also associated strongly and positively with high and medium traffic within 150 m of the school. JF - Environmental Health Perspectives AU - Green, Rochelle S AU - Smorodinsky, Svetlana AU - Kim, Janice J AU - McLaughlin, Robert AU - Ostro, Bart Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 61 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SCHOOLS KW - AUTOMOBILE EMISSIONS KW - SPATIAL COMPARISONS KW - EDUCATION, PUBLIC KW - ENV JUSTICE KW - CALIFORNIA KW - SOCIOECONOMICS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - TRAFFIC, VEHICULAR KW - NATIONALITY COMPARISONS KW - STREETS AND ROADS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14681649?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Proximity+of+California+Public+Schools+to+Busy+Roads&rft.au=Green%2C+Rochelle+S%3BSmorodinsky%2C+Svetlana%3BKim%2C+Janice+J%3BMcLaughlin%2C+Robert%3BOstro%2C+Bart&rft.aulast=Green&rft.aufirst=Rochelle&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; CALIFORNIA; SOCIOECONOMICS; GEOGRAPHIC INFORMATION SYSTEMS; SCHOOLS; TRAFFIC, VEHICULAR; AUTOMOBILE EMISSIONS; NATIONALITY COMPARISONS; SPATIAL COMPARISONS; EDUCATION, PUBLIC; STREETS AND ROADS ER - TY - JOUR T1 - Brominated Flame Retardants: Cause for Concern? AN - 14681137; 10656104 JF - Environmental Health Perspectives AU - Birnbaum, Linda S AU - Staskal, Daniele F Y1 - 2004/01// PY - 2004 DA - Jan 2004 SP - 9 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 1 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOACCUMULATION, ANIMAL KW - BROMINE KW - POLLUTANT FATE KW - TOXICOLOGY KW - RISK ASSESSMENT KW - DATA, CHEMICAL KW - FLAME RETARDANTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14681137?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Brominated+Flame+Retardants%3A+Cause+for+Concern%3F&rft.au=Birnbaum%2C+Linda+S%3BStaskal%2C+Daniele+F&rft.aulast=Birnbaum&rft.aufirst=Linda&rft.date=2004-01-01&rft.volume=112&rft.issue=1&rft.spage=9&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; BIOACCUMULATION, ANIMAL; DATA, CHEMICAL; BROMINE; POLLUTANT FATE; TOXICOLOGY; FLAME RETARDANTS ER - TY - JOUR T1 - Conserved Pore Residues in the AAA Protease FtsH Are Important for Proteolysis and Its Coupling to ATP Hydrolysis AN - 19226751; 5774408 AB - Like other AAA proteins, Escherichia coli FtsH, a membrane-bound AAA protease, contains highly conserved aromatic and glycine residues (Phe super(228) and Gly super(230)) that are predicted to lie in the central pore region of the hexamer. The functions of Phe super(228) and Gly super(230) were probed by site-directed mutagenesis. The results of both in vivo and in vitro assays indicate that these conserved pore residues are important for FtsH function and that bulkier, uncharged/apolar residues are essential at position 228. None of the point mutants, F228A, F228E, F228K, or G230A, was able to degrade capital sigma super(32), a physiological substrate. The F228A mutant was able to degrade casein, an unfolded substrate, although the other three mutants were not. Mutation of these two pore residues also affected the ATPase activity of FtsH. The F228K and G230A mutations markedly reduced ATPase activity, whereas the F228A mutation caused a more modest decrease in this activity. The F228E mutant was actually more active ATPase. The substrates, capital sigma super(32) and casein, stimulated the ATPase activity of wild type FtsH. The ATPase activity of the mutants was no longer stimulated by casein, whereas that of the three Phe super(228) mutants, but not the G230A mutant, remained capital sigma super(32)-stimulatable. These results suggest that Phe super(228) and Gly super(230) in the predicted pore region of the FtsH hexamer have important roles in proteolysis and its coupling to ATP hydrolysis. JF - Journal of Biological Chemistry AU - Yamada-Inagawa, T AU - Okuno, T AU - Karata, K AU - Yamanaka, K AU - Ogura, T AD - Division of Molecular Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 862-0976, Japan, ogura@gpo.kumamoto-u.ac.jp Y1 - 2003/12/12/ PY - 2003 DA - 2003 Dec 12 SP - 50182 EP - 50187 PB - American Society for Biochemistry and Molecular Biology, 9650 Rockville Pike Bethesda MD 20814-3996 USA, [mailto:asbmb@asbmb.faseb.org], [URL:http://www.jbc.org] VL - 278 IS - 50 SN - 0021-9258, 0021-9258 KW - FtsH protein KW - sigma 32 Factor KW - casein KW - Microbiology Abstracts B: Bacteriology; Biochemistry Abstracts 2: Nucleic Acids KW - s32 Factor KW - Site-directed mutagenesis KW - Proteolysis KW - Adenosinetriphosphatase KW - Casein KW - Escherichia coli KW - Proteinase KW - Sigma factor KW - J 02728:Enzymes KW - N 14681:Mutagenesis techniques UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19226751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Biological+Chemistry&rft.atitle=Conserved+Pore+Residues+in+the+AAA+Protease+FtsH+Are+Important+for+Proteolysis+and+Its+Coupling+to+ATP+Hydrolysis&rft.au=Yamada-Inagawa%2C+T%3BOkuno%2C+T%3BKarata%2C+K%3BYamanaka%2C+K%3BOgura%2C+T&rft.aulast=Yamada-Inagawa&rft.aufirst=T&rft.date=2003-12-12&rft.volume=278&rft.issue=50&rft.spage=50182&rft.isbn=&rft.btitle=&rft.title=Journal+of+Biological+Chemistry&rft.issn=00219258&rft_id=info:doi/10.1074%2Fjbc.M308327200 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Escherichia coli; Proteinase; Adenosinetriphosphatase; Proteolysis; Site-directed mutagenesis; Sigma factor; Casein DO - http://dx.doi.org/10.1074/jbc.M308327200 ER - TY - JOUR T1 - A Salmonella protein causes macrophage cell death by inducing autophagy AN - 17906099; 5864835 AB - Salmonella enterica, the causative agent of food poisoning and typhoid fever, induces programmed cell death in macrophages, a process found to be dependent on a type III protein secretion system, and SipB, a protein with membrane fusion activity that is delivered into host cells by this system. When expressed in cultured cells, SipB caused the formation of and localized to unusual multimembrane structures. These structures resembled autophagosomes and contained both mitochondrial and endoplasmic reticulum markers. A mutant form of SipB devoid of membrane fusion activity localized to mitochondria, but did not induce the formation of membrane structures. Upon Salmonella infection of macrophages, SipB was found in mitochondria, which appeared swollen and devoid of christae. Salmonella-infected macrophages exhibited marked accumulation of autophagic vesicles. We propose that Salmonella, through the action of SipB, kills macrophages by disrupting mitochondria, thereby inducing autophagy and cell death. JF - Journal of Cell Biology AU - Hernandez, L D AU - Pypaert, M AU - Flavell, R A AU - Galan, JE AD - Section of Microbial Pathogenesis, Yale University School of Medicine, BCMM 354, 295 Congress Ave., New Haven, CT 06536-0812, USA, jorge.galan@yale.edu Y1 - 2003/12/08/ PY - 2003 DA - 2003 Dec 08 SP - 1123 EP - 1131 VL - 163 IS - 5 SN - 0021-9525, 0021-9525 KW - SipB protein KW - autophagosomes KW - autophagy KW - christae KW - secretion system (type III) KW - Microbiology Abstracts B: Bacteriology KW - Macrophages KW - Cell death KW - Membranes KW - Membrane fusion KW - Salmonella enterica KW - Mitochondria KW - Food poisoning KW - Typhoid fever KW - Mutants KW - J 02727:Amino acids, peptides and proteins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17906099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Cell+Biology&rft.atitle=A+Salmonella+protein+causes+macrophage+cell+death+by+inducing+autophagy&rft.au=Hernandez%2C+L+D%3BPypaert%2C+M%3BFlavell%2C+R+A%3BGalan%2C+JE&rft.aulast=Hernandez&rft.aufirst=L&rft.date=2003-12-08&rft.volume=163&rft.issue=5&rft.spage=1123&rft.isbn=&rft.btitle=&rft.title=Journal+of+Cell+Biology&rft.issn=00219525&rft_id=info:doi/10.1083%2Fjcb.200309161 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Macrophages; Cell death; Membranes; Membrane fusion; Food poisoning; Mitochondria; Typhoid fever; Mutants; Salmonella enterica DO - http://dx.doi.org/10.1083/jcb.200309161 ER - TY - JOUR T1 - Kangaroos avoid eating seedlings with or near others with volatile essential oils. AN - 71534034; 14969351 AB - Preliminary studies indicate that western grey kangaroos browse seedlings of non-Myrtaceae species rather than Myrtaceae. Seven morphologically-matched species pairs of Myrtaceae/non-Myrtaceae placed at three field sites showed that kangaroos avoided the essential-oil-containing Myrtaceae, but readily consumed the matched essential-oil-lacking non-Myrtaceae. The one exception (Pittosporaceae) had limited herbivory and was later found to possess two essential oils in its leaves. Gas chromatography and mass-spectra showed the seven Myrtaceae plants contain between 2 and 9 essential oils in their leaves, particularly the highly volatile monoterpene, 2,5-dimethyl-3-methylene-1,5-heptadine. Three of the above species pairs were used to gauge their effectiveness as nurse plants for a highly palatable legume. Plants placed beside Myrtaceae nurse plants were less browsed than those placed beside non-Myrtaceae nurse plants. We conclude that western grey kangaroos use olfactory cues to avoid foliage containing potentially toxic essential oils, and that this also has implications for seedling recruitment patterns in regenerating communities. JF - Journal of chemical ecology AU - Jones, Anthea S AU - Lamont, Byron B AU - Fairbanks, Meredith M AU - Rafferty, Christine M AD - Department of Environmental Biology, Curtin University of Technology, GPO Box U1987, Perth, Western Australia 6845, Australia. Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 2621 EP - 2635 VL - 29 IS - 12 SN - 0098-0331, 0098-0331 KW - Oils, Volatile KW - 0 KW - Index Medicus KW - Animals KW - Plants, Edible KW - Gas Chromatography-Mass Spectrometry KW - Seedlings -- chemistry KW - Macropodidae KW - Oils, Volatile -- analysis KW - Myrtaceae -- chemistry KW - Feeding Behavior KW - Smell KW - Oils, Volatile -- poisoning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71534034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chemical+ecology&rft.atitle=Kangaroos+avoid+eating+seedlings+with+or+near+others+with+volatile+essential+oils.&rft.au=Jones%2C+Anthea+S%3BLamont%2C+Byron+B%3BFairbanks%2C+Meredith+M%3BRafferty%2C+Christine+M&rft.aulast=Jones&rft.aufirst=Anthea&rft.date=2003-12-01&rft.volume=29&rft.issue=12&rft.spage=2621&rft.isbn=&rft.btitle=&rft.title=Journal+of+chemical+ecology&rft.issn=00980331&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-06 N1 - Date created - 2004-02-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A systematic review of school drug education. AN - 71438396; 14654505 AB - This paper provides an up-to-date systematic review of the school drug education literature (to June 2001) and identifies components that have the potential for creating effective drug education programmes in schools. This paper is a summary of a 150-page review. The review adopts a well-defined search methodology, specific selection criteria, and has made a series of recommendations based on the findings of past reviews and recent primary studies that met the selection criteria. The review is inclusive of reviews and recent primary studies that involved young people in school settings that encompassed a classroom intervention, included drug-related behavioural measures and had a positive impact on students' drug-related behaviours. The review identifies several areas that should be the focus of future programmes. These include timing and programming issues, content and delivery issues, teacher training, and dissemination. There is much refinement that can occur in school drug education implementation and research. The way forward is to continue to create and test interventions that bring together all components of the development, implementation and evaluation of school drug education that are effective in creating behaviour change, and that are practical to the school setting. JF - Health education research AU - McBride, Nyanda AD - National Drug Research Institute, GPO Box U1987, Perth, WA 6845, Australia. nyanda@ndri.curtin.edu.au Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 729 EP - 742 VL - 18 IS - 6 SN - 0268-1153, 0268-1153 KW - Health technology assessment KW - Teaching -- methods KW - Humans KW - Australia KW - Marketing -- methods KW - Adolescent KW - Male KW - Female KW - Schools KW - Curriculum KW - Health Education -- methods KW - Substance-Related Disorders -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71438396?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+education+research&rft.atitle=A+systematic+review+of+school+drug+education.&rft.au=McBride%2C+Nyanda&rft.aulast=McBride&rft.aufirst=Nyanda&rft.date=2003-12-01&rft.volume=18&rft.issue=6&rft.spage=729&rft.isbn=&rft.btitle=&rft.title=Health+education+research&rft.issn=02681153&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-02-05 N1 - Date created - 2003-12-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Mechanotransduction by intraganglionic laminar endings of vagal tension receptors in the guinea-pig oesophagus. AN - 71427265; 14500769 AB - Vagal mechanoreceptors to the guinea-pig oesophagus, recorded extracellularly, in vitro, fired spontaneously at 3.3 +/- 0.2 Hz, (n = 75, from 57 animals), and had low thresholds to circumferential stretch. In this study, we have investigated whether mechanotransduction by intraganglionic laminar endings (IGLEs) directly relies on mechano-gated ion channels, or whether it is due to chemical activation by neurotransmitters (glutamate or ATP) released from other cells during mechanical distortion. Rapid distortion of focal transduction sites (IGLEs) evoked action potentials with a latency of < 10 ms. Antagonists to ionotropic (AP5, memantine and 6,7-dinitroquinoxaline-2,3-dione (DNQX)) and metabotropic glutamate receptors (N-phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide (PHCCC) and (RS)-a-methyl-4-phosphono-phenylglycine (MPPG)) did not affect mechano-transduction. Glutamate, NMDA and the selective mGluR group II and III agonists, (2R, 4R)-APDC and L-AP4, had no effect on spontaneous or stretch-induced firing. The P2X purinoreceptor agonist, alpha,beta-methylene ATP, caused concentration-dependent excitation of vagal mechanoreceptors (EC50 = 22.2 microM) which was blocked by the non-selective P2 antagonist PPADS (30 microM). On its own, PPADS affected neither stretch-induced firing nor spontaneous firing. Neither Ca(2+)-free solution (1 mM EDTA, 3.6 mM Mg(2+)) solution nor Cd(2+) (100 microM) blocked stretch-induced firing. Thus chemical transmission is not involved in activation of vagal mechanoreceptors. The blocker of stretch-activated channels, Gd(3+) (300 microM), did not inhibit stretch-induced firing. However, benzamil (100 microM) significantly inhibited spontaneous and distension-evoked firing in a stretch-dependent manner; proportionally greater inhibition was seen with larger stretches. The results suggest that IGLEs of vagal tension receptors directly transduce mechanical stimuli probably via benzamil-sensitive, Gd3+-insensitive, stretch-activated ion channels, and that chemical transmission is not involved in transduction. JF - The Journal of physiology AU - Zagorodnyuk, Vladimir P AU - Chen, Bao Nan AU - Costa, Marcello AU - Brookes, Simon J H AD - Department of Human Physiology and Centre for Neuroscience, Flinders University of South Australia, GPO Box 2100, Adelaide, South Australia. vladimir.zagorodnyuk@flinders.edu.au Y1 - 2003/12/01/ PY - 2003 DA - 2003 Dec 01 SP - 575 EP - 587 VL - 553 SN - 0022-3751, 0022-3751 KW - Carrier Proteins KW - 0 KW - Excitatory Amino Acid Agonists KW - Excitatory Amino Acid Antagonists KW - Membrane Transport Proteins KW - P2RX2 protein, human KW - Purinergic P2 Receptor Agonists KW - Purinergic P2 Receptor Antagonists KW - Receptors, Purinergic P2 KW - Receptors, Purinergic P2X2 KW - Synaptophysin KW - Vesicular Glutamate Transport Protein 1 KW - Vesicular Glutamate Transport Protein 2 KW - Vesicular Transport Proteins KW - Cadmium KW - 00BH33GNGH KW - benzamil KW - 04659UUJ94 KW - pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid KW - 149017-66-3 KW - Glutamic Acid KW - 3KX376GY7L KW - Tetrodotoxin KW - 4368-28-9 KW - Pyridoxal Phosphate KW - 5V5IOJ8338 KW - Amiloride KW - 7DZO8EB0Z3 KW - Adenosine Triphosphate KW - 8L70Q75FXE KW - Gadolinium KW - AU0V1LM3JT KW - alpha,beta-methyleneadenosine 5'-triphosphate KW - NYX13NT29D KW - Calcium KW - SY7Q814VUP KW - Memantine KW - W8O17SJF3T KW - Index Medicus KW - Gadolinium -- pharmacology KW - Animals KW - Guinea Pigs KW - Calcium -- pharmacology KW - Action Potentials -- drug effects KW - Electric Stimulation KW - Receptors, Purinergic P2 -- analysis KW - Excitatory Amino Acid Antagonists -- pharmacology KW - Cadmium -- pharmacology KW - Stress, Mechanical KW - In Vitro Techniques KW - Excitatory Amino Acid Agonists -- pharmacology KW - Action Potentials -- physiology KW - Dose-Response Relationship, Drug KW - Memantine -- pharmacology KW - Glutamic Acid -- pharmacology KW - Synaptophysin -- analysis KW - Carrier Proteins -- analysis KW - Tetrodotoxin -- pharmacology KW - Immunohistochemistry KW - Ganglia -- cytology KW - Ganglia -- physiology KW - Mechanotransduction, Cellular -- physiology KW - Amiloride -- pharmacology KW - Nerve Endings -- cytology KW - Amiloride -- analogs & derivatives KW - Nerve Endings -- physiology KW - Ganglia -- chemistry KW - Vagus Nerve -- physiology KW - Adenosine Triphosphate -- analogs & derivatives KW - Mechanotransduction, Cellular -- drug effects KW - Pyridoxal Phosphate -- pharmacology KW - Mechanoreceptors -- drug effects KW - Mechanoreceptors -- physiology KW - Pyridoxal Phosphate -- analogs & derivatives KW - Esophagus -- physiology KW - Nerve Endings -- drug effects KW - Adenosine Triphosphate -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71427265?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+physiology&rft.atitle=Mechanotransduction+by+intraganglionic+laminar+endings+of+vagal+tension+receptors+in+the+guinea-pig+oesophagus.&rft.au=Zagorodnyuk%2C+Vladimir+P%3BChen%2C+Bao+Nan%3BCosta%2C+Marcello%3BBrookes%2C+Simon+J+H&rft.aulast=Zagorodnyuk&rft.aufirst=Vladimir&rft.date=2003-12-01&rft.volume=553&rft.issue=&rft.spage=575&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+physiology&rft.issn=00223751&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-09-23 N1 - Date created - 2003-12-03 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Proc Natl Acad Sci U S A. 2000 May 23;97(11):6120-5 [10823955] J Neurosci. 1997 Jun 15;17(12):4764-84 [9169536] Neurogastroenterol Motil. 2000 Jun;12(3):257-64 [10867623] J Physiol. 2000 Jul 15;526 Pt 2:375-85 [10896726] J Neurosci. 2000 Aug 15;20(16):6249-55 [10934275] Nature. 2000 Sep 14;407(6801):189-94 [11001057] Nature. 2000 Oct 26;407(6807):1007-11 [11069180] Brain Res. 2000 Nov 24;884(1--2):1-12 [11082481] Circ Res. 2001 Feb 16;88(3):325-32 [11179201] Physiol Rev. 2001 Apr;81(2):685-740 [11274342] Trends Pharmacol Sci. 2001 Apr;22(4):182-8 [11282418] J Neurosci. 2001 Apr 15;21(8):2678-86 [11306621] Gastroenterology. 2001 Jun;120(7):1737-48 [11375955] Curr Opin Neurobiol. 2001 Jun;11(3):320-6 [11399430] Am J Physiol Heart Circ Physiol. 2001 Jul;281(1):H457-62 [11406515] J Physiol. 2001 Jul 1;534(Pt 1):255-68 [11433006] Ann N Y Acad Sci. 2001 Jun;940:42-7 [11458698] J Neurosci. 2001 Aug 1;21(15):5670-7 [11466438] Br J Pharmacol. 2001 Aug;133(8):1255-62 [11498511] Neuron. 2001 Aug 2;31(2):247-60 [11502256] Nature. 2001 Sep 13;413(6852):194-202 [11557988] Neurochem Res. 2001 Sep;26(8-9):959-69 [11699948] Am J Physiol Renal Physiol. 2002 Feb;282(2):F281-8 [11788442] J Biol Chem. 2002 Jan 25;277(4):2369-72 [11706013] J Neurophysiol. 2002 Apr;87(4):2095-103 [11929927] Clin Exp Pharmacol Physiol. 2002 May-Jun;29(5-6):522-4 [12010202] Histochem Cell Biol. 2002 May;117(5):415-22 [12029488] J Physiol. 2002 Jun 1;541(Pt 2):591-600 [12042363] J Biol Chem. 2002 Jun 14;277(24):21617-23 [11943785] Auton Neurosci. 2002 Jun 28;98(1-2):59-63 [12144042] Neuroscience. 2002;113(4):809-23 [12182888] Annu Rev Genet. 2002;36:411-53 [12429699] Br J Pharmacol. 2002 Dec;137(8):1195-206 [12466228] Auton Neurosci. 2002 Nov 29;102(1-2):20-9 [12492132] Neuropharmacology. 2002 Dec;43(8):1313-23 [12527481] Cell Tissue Res. 2003 May;312(2):141-8 [12698357] Am J Physiol. 1997 Sep;273(3 Pt 1):G661-9 [9316470] Br J Pharmacol. 1998 Jan;123(1):122-8 [9484862] J Physiol. 1998 Jun 1;509 ( Pt 2):411-7 [9575290] J Physiol. 1998 Jul 1;510 ( Pt 1):27-35 [9625864] Pharmacol Rev. 1998 Sep;50(3):413-92 [9755289] J Physiol. 1999 Apr 15;516 ( Pt 2):525-38 [10087350] Neurosci Lett. 1999 Oct 8;273(3):179-82 [10515188] Brain Res. 1985 Aug 5;340(1):143-7 [2411348] J Auton Nerv Syst. 1987 Oct;20(3):243-55 [3693803] J Physiol. 1987 Dec;394:149-72 [2451016] Am J Physiol. 1992 May;262(5 Pt 2):H1415-21 [1590446] J Neurosci. 1992 Jun;12(6):2251-8 [1351539] Jpn J Physiol. 1993;43(6):785-96 [8007447] Biophys J. 1994 Jul;67(1):71-83 [7919027] J Neurophysiol. 1994 Jul;72(1):421-30 [7965024] J Neurophysiol. 1995 May;73(5):2094-8 [7623100] Nature. 1995 Oct 5;377(6548):428-31 [7566119] Nature. 1995 Oct 5;377(6548):432-5 [7566120] Cell Tissue Res. 1995 Dec;282(3):423-33 [8581936] Neuroscience. 1995 May;66(2):433-41 [7477884] Pharmacol Rev. 1996 Jun;48(2):231-52 [8804105] Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10465-70 [8816824] Br J Pharmacol. 1996 Nov;119(5):779-86 [8922721] Neurosci Lett. 1996 Feb 2;204(1-2):9-12 [8929965] J Neurosci. 1997 Feb 1;17(3):904-16 [8994045] J Physiol. 1997 Feb 15;499 ( Pt 1):27-46 [9061638] Am J Physiol. 1997 Feb;272(2 Pt 1):G357-66 [9124361] J Physiol. 2000 Mar 1;523 Pt 2:403-11 [10699084] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Metal degradation products: a cause for concern in metal-metal bearings? AN - 71412785; 14646711 AB - In the majority of patients, orthopaedic implants are biocompatible. However, there is an increasing recognition that, in the long-term, permanent orthopaedic implants may be associated with adverse local and remote tissue responses in some individuals. These adverse effects are mediated by the degradation products of implant materials. The recent reintroduction of metal-on-metal bearings for total hip arthroplasty has heightened concerns about the biologic response to metal degradation products in light of the fact that the serum and urine metal concentrations in patients with these implants typically are higher than those seen in patients with conventional metal-on-polyethylene bearings. From previous studies of long-term metal-on-metal McKee-Farrar implants, it seems that these elevated levels may persist for the duration of the implant's lifetime. This is of particular concern in the younger and more active patient in whom life expectancy after implantation may exceed 30 years. The association of metal release from orthopaedic implants with any metabolic, bacteriologic, immunologic, or carcinogenic toxicity currently remains conjectural because cause and effect have not been established in human subjects. However, continued surveillance of patient populations with metal implants, particularly those with metal-metal bearings, is warranted. JF - Clinical orthopaedics and related research AU - Jacobs, Joshua J AU - Hallab, Nadim J AU - Skipor, Anastasia K AU - Urban, Robert M AD - Department of Orthopedic Surgery, Rush Medical College, 1653 W. Congress Parkway, Chicago, IL 60612, USA. jjacobs@rush.edu Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 139 EP - 147 IS - 417 SN - 0009-921X, 0009-921X KW - Metals KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - Humans KW - Neoplasms -- chemically induced KW - Hypersensitivity -- etiology KW - Orthopedic Procedures KW - Metals -- adverse effects KW - Foreign Bodies -- metabolism KW - Metals -- metabolism KW - Prostheses and Implants -- adverse effects KW - Foreign Bodies -- complications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71412785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+orthopaedics+and+related+research&rft.atitle=Metal+degradation+products%3A+a+cause+for+concern+in+metal-metal+bearings%3F&rft.au=Jacobs%2C+Joshua+J%3BHallab%2C+Nadim+J%3BSkipor%2C+Anastasia+K%3BUrban%2C+Robert+M&rft.aulast=Jacobs&rft.aufirst=Joshua&rft.date=2003-12-01&rft.volume=&rft.issue=417&rft.spage=139&rft.isbn=&rft.btitle=&rft.title=Clinical+orthopaedics+and+related+research&rft.issn=0009921X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-01-06 N1 - Date created - 2003-12-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Leishmania amazonensis Rab7 promotes toxicity of the amino acid ester Leu-OMe in amastigote megasomes. AN - 71342095; 14599671 JF - Molecular and biochemical parasitology AU - Huynh, Chau AU - Andrews, Norma W AD - Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 101 EP - 104 VL - 132 IS - 2 SN - 0166-6851, 0166-6851 KW - Protozoan Proteins KW - 0 KW - rab7 protein KW - 152989-05-4 KW - leucine methyl ester KW - 2666-93-5 KW - rab GTP-Binding Proteins KW - EC 3.6.5.2 KW - Leucine KW - GMW67QNF9C KW - Index Medicus KW - Protozoan Proteins -- drug effects KW - Animals KW - Kinetics KW - Protozoan Proteins -- genetics KW - Protozoan Proteins -- physiology KW - Mutagenesis KW - Leucine -- analogs & derivatives KW - rab GTP-Binding Proteins -- physiology KW - Leucine -- toxicity KW - Leishmania mexicana -- drug effects KW - rab GTP-Binding Proteins -- genetics KW - Leishmania mexicana -- physiology KW - rab GTP-Binding Proteins -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71342095?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+and+biochemical+parasitology&rft.atitle=Leishmania+amazonensis+Rab7+promotes+toxicity+of+the+amino+acid+ester+Leu-OMe+in+amastigote+megasomes.&rft.au=Huynh%2C+Chau%3BAndrews%2C+Norma+W&rft.aulast=Huynh&rft.aufirst=Chau&rft.date=2003-12-01&rft.volume=132&rft.issue=2&rft.spage=101&rft.isbn=&rft.btitle=&rft.title=Molecular+and+biochemical+parasitology&rft.issn=01666851&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-02-13 N1 - Date created - 2003-11-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Current Strategic Business Plan for the Implementation of Digital Systems. AN - 62179743; ED482968 AB - This document presents a current strategic business plan for the implementation of digital systems and services for the free national library program operated by the National Library Service for the Blind and Physically Handicapped, Library of Congress, its network of cooperating regional and local libraries, and the United States Postal Service. The program was established in 1931 and is funded annually by Congress. The plan will be updated and refined as supporting future studies are completed. (AMT) Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 245 PB - Reference Section, National Library Service for the Blind and Physically Handicapped, Library of Congress, Washington, DC 20542. For full text: http://www.loc.gov.html. KW - ERIC, Resources in Education (RIE) KW - Computer System Design KW - Library Networks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62179743?accountid=14244 LA - English DB - ERIC N1 - Availability - Level 1 - Available online, if indexed January 1993 onward N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - The Law: Congressional Access to Presidential Documents: The House Resolution of Inquiry AN - 60703422; 200410509 AB - The resolution of inquiry is a House procedure that seeks factual information from the executive branch, either from the president or department heads. The resolution is privileged & may be considered at any time after it is reported or discharged from committee. It applies only to requests for facts -- not opinions -- within the administration's control. Even when a resolution of inquiry is reported adversely from a committee & tabled on the floor, it frequently leads to the release of a substantial amount of information from the executive branch that can alter presidential policy in both military & domestic affairs. 21 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Fisher, Louis AD - Congressional Research Service, Library Congress Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 898 EP - 912 VL - 33 IS - 4 SN - 0360-4918, 0360-4918 KW - Presidents KW - Freedom of Information KW - United States of America KW - Documents KW - Legislative Bodies KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60703422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=The+Law%3A+Congressional+Access+to+Presidential+Documents%3A+The+House+Resolution+of+Inquiry&rft.au=Fisher%2C+Louis&rft.aulast=Fisher&rft.aufirst=Louis&rft.date=2003-12-01&rft.volume=33&rft.issue=4&rft.spage=898&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 21 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Presidents; Freedom of Information; Documents; Legislative Bodies; United States of America ER - TY - JOUR T1 - Partial-Birth Abortion Ban Act 2003 AN - 57131260; 267476 AB - Congress passed an Act to prohibit the procedure known as partial-birth abortion on 5th November, 2003 and President Bush signed it into law just before Christmas. Unlike UK Acts, it includes a summary of the background to the law and of legislators' reasoning, part of which - concerned with whether findings of fact by the Supreme Court or by Congress are to be preferred - has been abridged in this version presented. (Original abstract) JF - Bulletin of Medical Ethics AU - US Congress AD - US Congress Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 8 EP - 11 IS - 194 SN - 0269-1485, 0269-1485 KW - USA KW - Law KW - Partial Birth Abortion Ban Act 2003 KW - Prohibition UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57131260?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+Medical+Ethics&rft.atitle=Partial-Birth+Abortion+Ban+Act+2003&rft.au=US+Congress&rft.aulast=US+Congress&rft.aufirst=&rft.date=2003-12-01&rft.volume=&rft.issue=194&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+Medical+Ethics&rft.issn=02691485&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2005-05-24 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Partial Birth Abortion Ban Act 2003; Prohibition; USA; Law ER - TY - JOUR T1 - UV photooxidation of NOM: issues related to drinking water treatment. AN - 28066918; 200407-41-04044 (CE); 05830050 (EN) AB - The effect of UVA (300-400 nm), UVB (260-340 nm) and UVC (254 nm) wavelengths on absorbance spectra, dissolved organic carbon (DOC) levels, molecular size distributions, bacterial regrowth potentials (BRP) and trihalomethane formation potentials (THMFP) of aquatic natural organic matter (NOM) from a number of sources was examined to ascertain the use of photooxidation for the removal of NOM from drinking water. Differences were observed in the normalized UV spectra of the NOM samples, and UVC-irradiation resulted in the largest reduction in absorbance at 254 nm and DOC levels. The various UV wavelengths appeared to reduce the molecular size in a similar fashion with sequential degradation from high molecular weight to low molecular weight by-products. Treatment by UVA-, UVB- and UVC-radiation also resulted in increased BRP for all NOM samples. The THMFP of the UV-treated NOM samples HV MIEX and HV Raw appeared to be dependent on the characteristics of the NOM sample and the UV dose. The THMFP of UVA- and UVB-irradiated HV MIEX increased and an initial increase was observed for UVC-irradiated HV MIEX before decreasing with further treatment, while UVC-irradiated HV Raw showed decreased THMFP for all treatment times. JF - Journal of Water Supply: Research & Technology - AQUA AU - Parkinson, A AU - Roddick, F A AU - Hobday, M D AD - School of Civil and Chemical Engineering, RMIT University, GPO Box 2476V, Melbourne 3001, VIC, Australia PY - 2003 SP - 577 EP - 586 PB - IWA Publishing, Commerce Way, Colchester, CO2 8HP, UK, [mailto:sales@portlandpress.com], [URL:http://www.iwapublishing.com] VL - 52 IS - 8 SN - 0003-7214, 0003-7214 KW - Civil Engineering (CE); Environmental Engineering (EN) KW - Drinking water KW - Spectra KW - Absorbance KW - Dissolution KW - Water supply KW - Bacteria KW - Degradation KW - Byproducts KW - Carbon KW - Article KW - EE 50:Water & Wastewater Treatment (EN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/28066918?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+Supply%3A+Research+%26+Technology+-+AQUA&rft.atitle=UV+photooxidation+of+NOM%3A+issues+related+to+drinking+water+treatment.&rft.au=Parkinson%2C+A%3BRoddick%2C+F+A%3BHobday%2C+M+D&rft.aulast=Parkinson&rft.aufirst=A&rft.date=2003-12-01&rft.volume=52&rft.issue=8&rft.spage=577&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+Supply%3A+Research+%26+Technology+-+AQUA&rft.issn=00037214&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Number of references - 40 N1 - Document feature - Graphs N1 - Last updated - 2011-11-11 ER - TY - JOUR T1 - Renal Disease in Captive Swift Parrots (Lathamus Discolor): Clinical Findings and Disease Management AN - 20192158; 5853303 AB - This report details the investigation of renal disease associated with neurologic signs and deaths in a captive research colony of the endangered swift parrot (Lathamus discolor). The syndrome affected birds irregularly during 11 months from October 1999 to September 2000. Ten birds from 4 aviaries were clinically affected, and 9 birds died. The most common clinical signs were weight loss, neurologic dysfunction (ataxia and generalized tremors), and articular gout. At necropsy, common findings included gross nephropathy, visceral gout, and gonadal regression or inflammation. Histopathologic changes included renal tubular degeneration and accumulations of black crystals, assumed to be urates, in renal tubules and collecting ducts. These histopathologic changes are nonspecific and could be associated with a wide variety of nephrotoxins including, but not limited to, heavy metals, organic solvents, phenol, antibacterial agents, pesticides, and ethylene glycol. The syndrome was associated with the feeding of a high-protein diet and the presence of nesting boxes and other environmental factors. A number of potentially toxic substances were found in the swift parrots' environment, including nitrate fertilizer, zinc from galvanized wire, and potentially toxic wood fragments (Tasmanian sassafras [Atherosperma moschatum]). However, not all affected birds were exposed to these toxins, or diagnostic testing ruled them out of consideration. Regardless of the initial cause of renal damage, the overall renal pathologic changes were consistent with a urate nephropathy. There is still uncertainty as to the initial cause of the neurologic disease and renal damage despite the intensive investigation described here. The immediate deterioration of 2 swift parrots after the reintroduction of the high-protein diet led us to suspect that dietary levels of protein might be a contributing factor to the renal disease. JF - Journal of Avian Medicine and Surgery AU - Gartrell, B D AU - Raidal AU - Jones, S M AD - From the School of Zoology, University of Tasmania, GPO Box 252-5, Hobart, Tasmania, 7001, Australia (Gartrell and Jones); and the Division of Veterinary and Biomedical Sciences, Murdoch University, WA, 6150, Australia (Raidal). Present address (Gartrell): Institute of Veterinary, Animal, and Biomedical Sciences, Massey University, Private Bag 11 222, Palmerston North, New Zealand Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 213 EP - 223 PB - Association of Avian Veterinarians VL - 17 IS - 4 SN - 1082-6742, 1082-6742 KW - Microbiology Abstracts B: Bacteriology KW - Nitrate KW - Autopsy KW - Neurological diseases KW - Heavy metals KW - Lathamus discolor KW - Crystals KW - Environmental factors KW - Colonies KW - Fertilizers KW - Atherosperma moschatum KW - Zinc KW - Nephropathy KW - Ataxia KW - Degeneration KW - Ethylene glycol KW - Antibacterial agents KW - tremor KW - Uric acid KW - Reintroduction KW - Diets KW - Feeding KW - Sassafras KW - Solvents KW - Kidney diseases KW - Toxins KW - Phenols KW - Gout KW - Inflammation KW - Collecting duct KW - renal tubules KW - Pesticides KW - Kidney KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20192158?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Avian+Medicine+and+Surgery&rft.atitle=Renal+Disease+in+Captive+Swift+Parrots+%28Lathamus+Discolor%29%3A+Clinical+Findings+and+Disease+Management&rft.au=Gartrell%2C+B+D%3BRaidal%3BJones%2C+S+M&rft.aulast=Gartrell&rft.aufirst=B&rft.date=2003-12-01&rft.volume=17&rft.issue=4&rft.spage=213&rft.isbn=&rft.btitle=&rft.title=Journal+of+Avian+Medicine+and+Surgery&rft.issn=10826742&rft_id=info:doi/10.1043%2F1082-6742%282003%29017%280213%3ARDICSP%292.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=1082-6742&volume=17&page=213 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Lathamus discolor; Sassafras; Atherosperma moschatum; Kidney diseases; Kidney; Uric acid; Gout; Nephropathy; Ethylene glycol; Solvents; tremor; Autopsy; Neurological diseases; Nitrate; Ataxia; Phenols; Fertilizers; Diets; Antibacterial agents; Pesticides; Toxins; Degeneration; Collecting duct; Crystals; Heavy metals; Reintroduction; renal tubules; Zinc; Feeding; Inflammation; Environmental factors; Colonies DO - http://dx.doi.org/10.1043/1082-6742(2003)017(0213:RDICSP)2.0.CO;2 ER - TY - JOUR T1 - Application of monoclonal antibody libraries for the measurement of glycation adducts AN - 19382272; 7151601 AB - Immunological approaches have been used to demonstrate the presence of advanced glycation end-products (AGEs) in several human and experimental animal tissues. We previously prepared polyclonal and monoclonal anti-AGE antibodies by immunizing AGE-modified proteins such as BSA and RNase. Although these antibodies contributed to demonstrate the presence of AGE-modified protein in vivo, the epitope structure of these antibodies had not been identified. We subsequently prepared several antibodies against AGE structures such as pentosidine, pyrraline, 3-deoxyglucosone imidazolone and N super( epsilon )-(carboxyethyl)lysine by immunizing single AGE structures. These structure-specific antibodies have greatly helped broaden our understanding of AGE structures in aging and age-enhanced disease process. Monoclonal anti-AGE antibody is also used for the identification of major AGE structures in some pathological tissues, such as human atherosclerosis lesions. Based on the strategy, we successfully identified a novel AGE structure named glycolaldehyde-pyridine, which is the major antigenic AGE derived from glycolaldehyde. Therefore a monoclonal antibody library for AGE structures has served an important role in the elucidation of the biological significance of AGE. JF - Biochemical Society Transactions AU - Nagai, R AU - Horiuchi, S AD - Department of Medical Biochemistry, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Honjo 1-1-1, Kumamoto 860-8556, Japan, horiuchi@gpo.kumamoto-u.ac.jp Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1438 EP - 1440 VL - 31 IS - 6 SN - 0300-5127, 0300-5127 KW - Biotechnology and Bioengineering Abstracts KW - Age composition KW - advanced glycosylation end products KW - Monoclonal antibodies KW - Adducts KW - Aging KW - pentosidine KW - glycolaldehyde KW - Ribonuclease KW - Arteriosclerosis KW - Glycosylation KW - Epitopes KW - W 30905:Medical Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19382272?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biochemical+Society+Transactions&rft.atitle=Application+of+monoclonal+antibody+libraries+for+the+measurement+of+glycation+adducts&rft.au=Nagai%2C+R%3BHoriuchi%2C+S&rft.aulast=Nagai&rft.aufirst=R&rft.date=2003-12-01&rft.volume=31&rft.issue=6&rft.spage=1438&rft.isbn=&rft.btitle=&rft.title=Biochemical+Society+Transactions&rft.issn=03005127&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Age composition; advanced glycosylation end products; Monoclonal antibodies; Adducts; Aging; glycolaldehyde; pentosidine; Ribonuclease; Glycosylation; Arteriosclerosis; Epitopes ER - TY - JOUR T1 - Surface energy budget and closure of the eastern Tibetan Plateau during the GAME-Tibet IOP 1998 AN - 19160034; 5756281 AB - Turbulent flux measurements based on the eddy correlation technique were conducted on the Tibetan Plateau during the Intensive Observation Period (IOP) of the GEWEX Asian Monsoon Experiment (GAME) in 1998. This paper presents on analysis of the surface energy budget and its closure at the Amdo planetary boundary layer site in the eastern Tibetan Plateau using GAME-Tibet IOP data. A seasonal variation in the surface energy closure ratio (CR) was seen. CR was higher than 0.8 in the pre-monsoon period and after DOY 233, when the infrared hygrometer was performing satisfactorily. However, CR was lower than 0.7 throughout most of the summer monsoon, due at least in part to degraded performance of the infrared hygrometer under heavy precipitation. In addition, through detail analysis of the diurnal variations of surface energy flux for the best-CR period of September 4-6, it was found that the melting and freezing of near-surface soil moisture plays a significant role in the variation of surface energy fluxes, particularly in terms of latent heat flux. The calculated effective mass of melting and freezing water in one day was 3.3-3.9 kg/m, which is comparable to the daily total. JF - Journal of Hydrology (Amsterdam) AU - Tanaka, K AU - Tamagawa, I AU - Ishikawa, H AU - Ma, Y AU - Hu, Z AD - Department of Civil and Environmental Engineering, Faculty of Engineering, Kumamoto University, Kurokami 2-39-1, Kumamoto 860 8555, Japan, ktanaka@gpo.kumamoto-u.ac.jp Y1 - 2003/12// PY - 2003 DA - December 2003 SP - 169 EP - 183 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 283 IS - 1-4 SN - 0022-1694, 0022-1694 KW - Asia, Tibetan Plateau KW - Meteorological & Geoastrophysical Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Tibetan Plateau KW - Surface energy flux KW - Eddy correlation KW - Closure ratio KW - Melting/freezing of soil moisture KW - Seasonal Variations KW - Heat exchange KW - Air-earth Interfaces KW - Heat Transfer KW - Melting KW - Turbulent flux measurements KW - Energy budget at Earth's surface KW - Asia KW - Data Interpretation KW - Seasonal variations KW - Data Collections KW - Summer monsoon KW - Project GEWEX KW - Freezing KW - China, People's Rep., Xizang, Tibetan Plateau KW - Energy KW - Seasons KW - Asian monsoons KW - Soil moisture KW - Monsoons KW - AQ 00001:Water Resources and Supplies KW - M2 551.551.21:Turbulence in the layers up to normal anemometer height (551.551.21) KW - SW 0830:Evaporation and transpiration KW - SW 0810:General KW - M2 551.511.6:Turbulence and diffusion (551.511.6) KW - M2 551.52:Radiation and Temperature (551.52) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19160034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hydrology+%28Amsterdam%29&rft.atitle=Surface+energy+budget+and+closure+of+the+eastern+Tibetan+Plateau+during+the+GAME-Tibet+IOP+1998&rft.au=Tanaka%2C+K%3BTamagawa%2C+I%3BIshikawa%2C+H%3BMa%2C+Y%3BHu%2C+Z&rft.aulast=Tanaka&rft.aufirst=K&rft.date=2003-12-01&rft.volume=283&rft.issue=1-4&rft.spage=169&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hydrology+%28Amsterdam%29&rft.issn=00221694&rft_id=info:doi/10.1016%2FS0022-1694%2803%2900243-9 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Project GEWEX; Summer monsoon; Turbulent flux measurements; Energy budget at Earth's surface; Asian monsoons; Soil moisture; Seasonal variations; Melting; Heat exchange; Energy; Seasons; Monsoons; Data Collections; Seasonal Variations; Freezing; Air-earth Interfaces; Heat Transfer; Data Interpretation; China, People's Rep., Xizang, Tibetan Plateau; Asia DO - http://dx.doi.org/10.1016/S0022-1694(03)00243-9 ER - TY - JOUR T1 - Fitness of the Endangered Pygmy Blue Tongue Lizard Tiliqua Adelaidensis in Artificial Burrows AN - 17307064; 5972703 AB - The endangered Pygmy Blue Tongue Lizard, Tiliqua adelaidensis, occupies narrow vertical burrows, probably constructed by spiders. We assessed the fitness of female lizards in artificial burrows added to a 1-ha plot within a natural population, over a three-year period. Compared with females in natural burrows, females in artificial burrows had significantly better body condition and produced larger offspring with better body condition. We discuss possible explanations for these differences but conclude that adding artificial burrows was not detrimental to reproductive females in a population and could be used in the conservation management of this species. JF - Journal of Herpetology AU - Milne, T AU - Bull, Michael, C AU - Hutchinson, M N AD - School of Biological Sciences, Flinders University, GPO Box 2100, Adelaide, South Australia 5001, Australia Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 762 EP - 765 PB - The Society for the Study of Amphibians and Reptiles VL - 37 IS - 4 SN - 0022-1511, 0022-1511 KW - Ecology Abstracts KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17307064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Herpetology&rft.atitle=Fitness+of+the+Endangered+Pygmy+Blue+Tongue+Lizard+Tiliqua+Adelaidensis+in+Artificial+Burrows&rft.au=Milne%2C+T%3BBull%2C+Michael%2C+C%3BHutchinson%2C+M+N&rft.aulast=Milne&rft.aufirst=T&rft.date=2003-12-01&rft.volume=37&rft.issue=4&rft.spage=762&rft.isbn=&rft.btitle=&rft.title=Journal+of+Herpetology&rft.issn=00221511&rft_id=info:doi/10.1043%2F0022-1511%282003%290372.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0022-1511&volume=37&page=762 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1043/0022-1511(2003)037<0762:FOTEPB>2.0.CO;2 ER - TY - JOUR T1 - Maximizing Resource Recovery from Waste Streams AN - 16171733; 5896724 AB - Resource conservation and waste management have become two sides of the same argument. According to the Institute for Local Self Reliance in the U.S., the recycling revolution begun in the 1960s was a reaction "to the levels of waste in our economy and the pollution and suffering these habits cause worldwide". However, the recycling target-setting of the early 1990s was focused on diversion from landfill, and it has taken another 10 years for the focus to shift back to the resource values approach, driven largely by the application of Life Cycle Assessment to the waste management system. This paper examines materials in the waste stream to determine the "value proposition" in each material group, and to examine options for efficient resource use and recovery. Specifically, it discusses waste management issues associated with clean fill, food waste, timber waste, concrete and bricks, green waste, paper and board, metals, plastics, and glass. JF - Environmental Progress AU - Grant, T AD - Centre for Design, Royal Melbourne Institute of Technology, GPO Box 2476V, Melbourne, Victoria 3001, Australia, tim.grant@rmit.edu.au Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 250 EP - 254 VL - 22 IS - 4 SN - 0278-4491, 0278-4491 KW - Pollution Abstracts; Sustainability Science Abstracts KW - Metals KW - Resource management KW - Life cycle analysis KW - Landfills KW - LCA KW - Glass KW - Recycling KW - Streams KW - Concrete KW - Solid wastes KW - Waste management KW - Environmental restoration KW - Conservation KW - Plastics KW - M3 1130:Water KW - P 4000:WASTE MANAGEMENT UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16171733?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Progress&rft.atitle=Maximizing+Resource+Recovery+from+Waste+Streams&rft.au=Grant%2C+T&rft.aulast=Grant&rft.aufirst=T&rft.date=2003-12-01&rft.volume=22&rft.issue=4&rft.spage=250&rft.isbn=&rft.btitle=&rft.title=Environmental+Progress&rft.issn=02784491&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2004-06-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Metals; Resource management; Landfills; LCA; Conservation; Environmental restoration; Plastics; Glass; Recycling; Concrete; Streams; Waste management; Life cycle analysis; Solid wastes ER - TY - JOUR T1 - Health, Wealth, and Air Pollution: Advancing Theory and Methods AN - 14681594; 10654820 AB - International organizations have identified both air pollution and poverty as priority areas for public-health intervention, but few studies have looked carefully at how these factors interact with one another. A review is provided of the underlying approaches in both fields, citing hypotheses of how air pollution and socioeconomic factors can interact to influence health. Considered are exposure differentials related to socioeconomic conditions, susceptibility related directly to social position, and susceptibility from predisposing health conditions, behaviors, or traits. Methodological issues in research design and analysis in this area are identified and discussed, which pertain to data sources and statistical analyses. JF - Environmental Health Perspectives AU - O'Neill, Marie S AU - Jerrett, Michael AU - Kawachi, Ichiro AU - Levy, Jonathan I AU - Cohen, Aaron J AU - Gouveia, Nelson AU - Wilkinson, Paul Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1861 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ENV JUSTICE KW - AIR POLLUTION EFFECTS KW - SOCIOECONOMICS KW - LOWER CLASS KW - AIR POLLUTION RESEARCH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14681594?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Health%2C+Wealth%2C+and+Air+Pollution%3A+Advancing+Theory+and+Methods&rft.au=O%27Neill%2C+Marie+S%3BJerrett%2C+Michael%3BKawachi%2C+Ichiro%3BLevy%2C+Jonathan+I%3BCohen%2C+Aaron+J%3BGouveia%2C+Nelson%3BWilkinson%2C+Paul&rft.aulast=O%27Neill&rft.aufirst=Marie&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1861&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; AIR POLLUTION EFFECTS; LOWER CLASS; SOCIOECONOMICS; AIR POLLUTION RESEARCH ER - TY - JOUR T1 - Hazardous Effects of Effluent from the Chrome Plating Industry: 70 kDa Heat Shock Protein Expression as a Marker of Cellular Damage in Transgenic Drosophila melanogaster (hsp70-lacZ) AN - 14681034; 10654830 AB - Heat shock protein 70 (hsp70) expression was examined in transgenic Drosophila melanogaster (hsp70-lacZ) Bg super(9)flies exposed to effluent from a chrome plating industry. Six concentrations of the effluent, ranging 0100 mu l/ml, were added to food. The emergence pattern of adult flies and their reproductive performance were also determined, and the highest nontoxic concentration of the effluent was determined by stress gene assay. The effluent was found to be highly toxic at higher concentrations, as indicated by hsp70 expression, trypan blue staining in reproductive organs, and overall effects on development. An insignificant regression in hsp70 expression was observed in the higher concentrations of the effluent once its maximum level had been reached. Expression of hsp70 was found in salivary glands, brain ganglia, proventriculus, gastric ceca, and midgut of the exposed larvae, and development was affected as evidenced by a delay in the emergence pattern of adult flies and a decrease in the number that emerged at the higher effluent concentrations. Male flies were found to be more sensitive than females. JF - Environmental Health Perspectives AU - Mukhopadhyay, Indranil AU - Saxena, Daya Krishna AU - Chowdhuri, Debapratim Kar Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1926 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DROSOPHILA KW - SEX COMPARISONS KW - CHROMIUM KW - CYTOTOXICITY KW - BIOLOGICAL INDICATORS KW - PROTEIN SYNTHESIS KW - METALLURGY KW - REPRODUCTION, INSECT KW - EFFLUENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14681034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Hazardous+Effects+of+Effluent+from+the+Chrome+Plating+Industry%3A+70+kDa+Heat+Shock+Protein+Expression+as+a+Marker+of+Cellular+Damage+in+Transgenic+Drosophila+melanogaster+%28hsp70-lacZ%29&rft.au=Mukhopadhyay%2C+Indranil%3BSaxena%2C+Daya+Krishna%3BChowdhuri%2C+Debapratim+Kar&rft.aulast=Mukhopadhyay&rft.aufirst=Indranil&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1926&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; DROSOPHILA; CHROMIUM; CYTOTOXICITY; BIOLOGICAL INDICATORS; REPRODUCTION, INSECT; PROTEIN SYNTHESIS; METALLURGY; EFFLUENTS ER - TY - JOUR T1 - Developmental Neurotoxicity Elicited by Gestational Exposure to Chlorpyrifos: When Is Adenylyl Cyclase a Target? AN - 14680975; 10654821 AB - Neurotransmitter receptors that control adenylyl cyclase, the enzyme responsible for cyclic AMP production, which coordinates the critical transition from cell replication to cell differentiation, and adenylyl cyclase itself have been found to be targets for chlorpyrifos, which suggest that the actions on the adenylyl cyclase pathway are among the critical targets of the insecticide in the developing brain. In this study, an in vivo exposure model was used to explore this concept. Chlorpyrifos regimens that bracketed the threshold for cholinesterase inhibition and resultant maternal/fetal toxicity were used, concentrating on two phases of development: an early stage involving formation of the neural tube, gestational days 912; and a later stage involving the transition from replication to differentiation of major neuronal cell populations, gestational days 1720. Chlorpyrifos was administered to pregnant rats. Results indicated that chlorpyrifos elicited developmental neurotoxicity through mechanisms independent of, and at doses below the threshold for, cholinesterase inhibition. The greatest period of sensitivity, by far, was late gestation after chlorpyrifos exposure on gestational days 1720. JF - Environmental Health Perspectives AU - Mayer, Armando AU - Seidler, Frederic J AU - Cousins, Mandy M AU - Slotkin, Theodore A Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1871 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - ENZYME ACTIVITY KW - CHLORPYRIFOS KW - REPRODUCTION, ANIMAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680975?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developmental+Neurotoxicity+Elicited+by+Gestational+Exposure+to+Chlorpyrifos%3A+When+Is+Adenylyl+Cyclase+a+Target%3F&rft.au=Mayer%2C+Armando%3BSeidler%2C+Frederic+J%3BCousins%2C+Mandy+M%3BSlotkin%2C+Theodore+A&rft.aulast=Mayer&rft.aufirst=Armando&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1871&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; ENZYME ACTIVITY; CHLORPYRIFOS; REPRODUCTION, ANIMAL ER - TY - JOUR T1 - Use of Biomarkers to Indicate Exposure of Children to Organophosphate Pesticides: Implications for a Longitudinal Study of Children's Environmental Health AN - 14680882; 10654832 AB - The use of biomarkers to determine adsorbed doses of environmental chemicals, such as organophosphate pesticides, is a critical issue for implementing the National Children's Study, which will be a large, multi-agency, long-term study of environmental influences on children's health and development. The dominant route of childhood exposure to organophosphate pesticides depends on a variety of dietary and behavioral factors. A discussion is provided of the use of biomarkers for such purposes, noting organophosphate pesticide metabolism, the measurement of cholinesterase inhibition in blood samples, monitoring organophosphate pesticide concentrations in blood or blood products, and the use of meconium, which begins to accumulate in the bowls of human fetuses at approximately 16 weeks gestation and is not excreted generally until after delivery. Study design issues are also considered. JF - Environmental Health Perspectives AU - Wessels, Denise AU - Barr, Dana B AU - Mendola, Pauline Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1939 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOLOGICAL INDICATORS KW - CHOLINESTERASE KW - MEASUREMENTS AND SENSING KW - ORGANOPHOSPHATE PESTICIDES KW - BLOOD ANALYSIS KW - METABOLIC ACTIVATION KW - PATHOLOGY, CHILDREN KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680882?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Use+of+Biomarkers+to+Indicate+Exposure+of+Children+to+Organophosphate+Pesticides%3A+Implications+for+a+Longitudinal+Study+of+Children%27s+Environmental+Health&rft.au=Wessels%2C+Denise%3BBarr%2C+Dana+B%3BMendola%2C+Pauline&rft.aulast=Wessels&rft.aufirst=Denise&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1939&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; BLOOD ANALYSIS; ORGANOPHOSPHATE PESTICIDES; PATHOLOGY, CHILDREN; METABOLIC ACTIVATION; BIOLOGICAL INDICATORS; CHOLINESTERASE; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Biomonitoring of Chemical Exposure Among New York City Firefighters Responding to the World Trade Center Fire and Collapse AN - 14680827; 10654827 AB - Blood and urine samples were collected from New York City firefighters who had responded to the World Trade Center fire and collapse on September 11, 2001, and internal dose levels of fire-related chemicals were measured and related to firefighter activities. The firefighters were categorized into groups based on arrival time, number of work days at the World Trade Center, and unit assignment. The samples were collected during October 15, 2001. Firefighters in the Special Operations Command had higher concentrations of 11 chemicals compared to controls, which was also found for subjects in the other firefighter group. Firefighters present when the towers collapsed had higher levels of urinary antimony and cadmium compared to those who arrived after the collapse. Overall, known products of combustion, such as PAH metabolites, were present in higher amounts in exposed firefighters, as were levels of serum heptachlorodibenzodioxin and heptachlorodibenzofuran. JF - Environmental Health Perspectives AU - Edelman, Philip AU - Osterloh, John AU - Pirkle, James AU - Caudill, Sam P AU - Grainger, James AU - Jones, Robert AU - Blount, Ben Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1906 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ANTIMONY KW - POLYCHLORINATED DIBENZODIOXINS KW - POLYCHLORINATED DIBENZOFURANS KW - BIOACCUMULATION, HUMAN KW - POLYCYCLIC AROMATIC HYDROCARBON KW - HEALTH SAFETY, OCCUPATIONAL KW - BLOOD ANALYSIS KW - FIRE CONTROL KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680827?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biomonitoring+of+Chemical+Exposure+Among+New+York+City+Firefighters+Responding+to+the+World+Trade+Center+Fire+and+Collapse&rft.au=Edelman%2C+Philip%3BOsterloh%2C+John%3BPirkle%2C+James%3BCaudill%2C+Sam+P%3BGrainger%2C+James%3BJones%2C+Robert%3BBlount%2C+Ben&rft.aulast=Edelman&rft.aufirst=Philip&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1906&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ANTIMONY; HEALTH SAFETY, OCCUPATIONAL; FIRE CONTROL; BLOOD ANALYSIS; POLYCHLORINATED DIBENZODIOXINS; BIOACCUMULATION, HUMAN; POLYCHLORINATED DIBENZOFURANS; NEW YORK CITY; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - A Randomized Trial of Education to Prevent Lead Burden in Children at High Risk for Lead Exposure: Efficacy as Measured by Blood Lead Monitoring AN - 14680786; 10654833 AB - The Phillips Lead Project was a community-based, randomized, controlled trial of the effectiveness of intensive, culture-specific peer education in maintaining low blood lead levels in children from birth to 3 yr of age. The project was conducted in the Phillips Neighborhood in Minneapolis, MN, where pregnant women and mothers of young children were randomized to a control or an intervention group. The educational curriculum included information on the sources of Pb, health sequelae of Pb burden, and Pb exposure reduction strategies, including household cleaning, safe use of water, hygiene, and nutritional guidelines. All of the prevention information was provided in the form of brochures in the native language of each subject. Blood Pb levels were determined in children every four months from four months of age through the third birthday. A greater percentage of children in the intervention group maintained blood Pb levels < 10 mu g/dl compared with the control group, although the effect only bordered on significance. JF - Environmental Health Perspectives AU - Jordan, Catherine M AU - Yust, Becky L AU - Robison, Leslie L AU - Hannan, Peter AU - Deinard, Amos S Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1947 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MITIGATIVE MEASURES KW - LEAD POISONING KW - BLOOD LEAD LEVEL KW - CHEMICAL CONTAMINATION CONTROL KW - EDUCATION, PUBLIC KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Randomized+Trial+of+Education+to+Prevent+Lead+Burden+in+Children+at+High+Risk+for+Lead+Exposure%3A+Efficacy+as+Measured+by+Blood+Lead+Monitoring&rft.au=Jordan%2C+Catherine+M%3BYust%2C+Becky+L%3BRobison%2C+Leslie+L%3BHannan%2C+Peter%3BDeinard%2C+Amos+S&rft.aulast=Jordan&rft.aufirst=Catherine&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1947&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - LEAD POISONING; MITIGATIVE MEASURES; BLOOD LEAD LEVEL; CHEMICAL CONTAMINATION CONTROL; EDUCATION, PUBLIC ER - TY - JOUR T1 - The Level of Maternal Methemoglobin During Pregnancy in an Air-Polluted Environment AN - 14680715; 10654826 AB - Blood and urine samples were collected from pregnant women living near Plomin 1, a coal-powered thermoelectric power plant in Labin, Croatia, and levels of methemoglobin were determined. The subjects were divided into six groups on the basis of the location of residence around the power plant. The methemoglobin levels were considered in relation to air-quality data. A statistically significant positive correlation was found between the mean concentration of methemoglobin and the daily ground-level concentration of sulfur dioxide measured during the dirty sampling period, and during the clean sampling period, a significant downward trend in methemoglobin levels was noted. The frequencies of miscarriages and still births were significantly different between the clean and dirty periods, and cases of increased methemoglobin values were correlated with symptoms of preclampsia. Levels of sulfate in urine decreased significantly during the clean period and increased, albeit not significantly, during the dirty period. JF - Environmental Health Perspectives AU - Mohorovic, Lucijan Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1902 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SULFUR DIOXIDE KW - POWER PLANTS, COAL FIRED KW - AIR POLLUTION EFFECTS KW - PREGNANCY KW - CROATIA KW - BLOOD ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Level+of+Maternal+Methemoglobin+During+Pregnancy+in+an+Air-Polluted+Environment&rft.au=Mohorovic%2C+Lucijan&rft.aulast=Mohorovic&rft.aufirst=Lucijan&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1902&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; POWER PLANTS, COAL FIRED; CROATIA; AIR POLLUTION EFFECTS; BLOOD ANALYSIS; PREGNANCY ER - TY - JOUR T1 - In Vitro Activation of Cord Blood Mononuclear Cells and Cytokine Production in a Remote Coastal Population Exposed to Organochlorines and Methyl Mercury AN - 14680392; 10654834 AB - Pregnant women who had resided for at least 5 yr in communities of the Mid North Shore and Lower North Shore of the St. Lawrence River, PQ, Canada, were used as subjects to assess cellular activation and associated cytokine secretion in newborns in relation to prenatal organochlorine pesticide and methylmercury exposure. Membrane markers of T-cell activation were measured, along with in vitro cytokine secretion after mitogenic stimulation of cord blood immune cells obtained from newborns of a fish-eating population and those from a reference group. The mean concentrations of p,p'-DDE, hexachlorobenzene, and PCBs in the subsistence fishing group were 1.5, 1.6, and 2.5 times higher, respectively, than those in the reference group, while the mean blood Hg concentration was 1.8 times higher. No significant differences were found among the two groups in the proportions of cord blood T lymphocytes. Negative correlations were found, however, between tumor necrosis factor- alpha secretion and plasma lipid concentrations of PCBs, p,p'-DDE, and hexachlorobenzene. JF - Environmental Health Perspectives AU - Bilrha, Houda AU - Roy, Raynald AU - Moreau, Brigitte AU - Belles-Isles, Marthe AU - Dewailly, Eric AU - Ayotte, Pierre Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1952 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - METHYLMERCURY KW - QUEBEC PROVINCE KW - ORGANOCHLORINE PESTICIDES KW - BIOACCUMULATION, HUMAN KW - FOOD CONTAMINATION KW - IMMUNE RESPONSE KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680392?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=In+Vitro+Activation+of+Cord+Blood+Mononuclear+Cells+and+Cytokine+Production+in+a+Remote+Coastal+Population+Exposed+to+Organochlorines+and+Methyl+Mercury&rft.au=Bilrha%2C+Houda%3BRoy%2C+Raynald%3BMoreau%2C+Brigitte%3BBelles-Isles%2C+Marthe%3BDewailly%2C+Eric%3BAyotte%2C+Pierre&rft.aulast=Bilrha&rft.aufirst=Houda&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1952&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; METHYLMERCURY; REPRODUCTION, HUMAN; QUEBEC PROVINCE; BIOACCUMULATION, HUMAN; ORGANOCHLORINE PESTICIDES; IMMUNE RESPONSE; FOOD CONTAMINATION ER - TY - JOUR T1 - Perfluorooctanesulfonate and Other Fluorochemicals in the Serum of American Red Cross Adult Blood Donors AN - 14680333; 10654825 AB - Serum samples were obtained from adult donors at six American Red Cross blood banks, and the distribution of perfluorooctanesulfonate (PFOS) and six other fluorochemicals, some of which are PFOS precursors, was characterized. In total, 645 serum samples were analyzed, constituting 332 males and 313 females. The analytical and data-analysis procedures used are described. Only PFOS exhibited log-normal distribution, and for all donors, the geometric mean PFOS level of 34.9 ppb. Serum samples from males had significantly higher geometric means for PFOS compared to females, and the male samples also had significantly higher levels of perfluorooctanoate and perfluorohexanesulfonate. The adjusted mean serum PFOS concentrations were highest in samples from Charlotte, NC, and lowest in those from Boston, MA. Both N-ethyl perfluorooctanesulfonamidoacetate and N-methyl perfluorooctanesulfonamidoacetate, adjusted for age and sex, were significant predictors of PFOS levels. JF - Environmental Health Perspectives AU - Olsen, Geary W AU - Church, Timothy R AU - Miller, John P AU - Burris, Jean M AU - Hansen, Kristen J AU - Lundberg, James K AU - Armitage, John B Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1892 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - AGE COMPARISONS KW - BIOACCUMULATION, HUMAN KW - AREA COMPARISONS KW - BLOOD ANALYSIS KW - FLUORIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680333?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Perfluorooctanesulfonate+and+Other+Fluorochemicals+in+the+Serum+of+American+Red+Cross+Adult+Blood+Donors&rft.au=Olsen%2C+Geary+W%3BChurch%2C+Timothy+R%3BMiller%2C+John+P%3BBurris%2C+Jean+M%3BHansen%2C+Kristen+J%3BLundberg%2C+James+K%3BArmitage%2C+John+B&rft.aulast=Olsen&rft.aufirst=Geary&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1892&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 17 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AREA COMPARISONS; SEX COMPARISONS; BLOOD ANALYSIS; AGE COMPARISONS; FLUORIDES; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - The Type B Brevetoxin (PbTx-3) Adversely Affects Development, Cardiovascular Function, and Survival in Medaka (Oryzias latipes) Embryos AN - 14678392; 10654829 AB - Eggs of medaka Oryzias latipes were microinjected with the type B brevetoxin congener, PbTx-3, and effects on finfish development and survival were explored. The brevetoxin was administered as one of eight doses, with each dose covering a 1-ng range from 0 to 6 ng/egg, along with a final dose of 8.5 ng/egg. At doses exceeding 1 ng/egg, there was a significant increase in heart rate on embryonic day 6, and over the full range of exposure doses, increases in PbTx-3 resulted in tachycardia. For all doses exceeding 1 ng/egg, twitch duration decreased with increasing PbTx-3 concentration in a dose-dependent manner, but as the toxin doses increased, so did early deaths within each treatment group. An LD sub(50) for PbTx-3 of approximately 4 ng/egg was determined. JF - Environmental Health Perspectives AU - Colman, Jamie R AU - Ramsdell, John S Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1920 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - TOXIC SUBSTANCES KW - DOSE RESPONSE PROFILES KW - CARDIOVASCULAR EFFECTS KW - MORTALITY PATTERNS KW - RED TIDE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14678392?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Type+B+Brevetoxin+%28PbTx-3%29+Adversely+Affects+Development%2C+Cardiovascular+Function%2C+and+Survival+in+Medaka+%28Oryzias+latipes%29+Embryos&rft.au=Colman%2C+Jamie+R%3BRamsdell%2C+John+S&rft.aulast=Colman&rft.aufirst=Jamie&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1920&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; TOXIC SUBSTANCES; CARDIOVASCULAR EFFECTS; RED TIDE; MORTALITY PATTERNS ER - TY - JOUR T1 - OECD Validation of the Hershberger Assay in Japan: Phase 2 Dose Response of Methyltestosterone, Vinclozolin, and p,p'-DDE AN - 14678313; 10654828 AB - The Hershberger assay uses the androgen sensitivity of several accessory sex organs and tissues of the male reproductive tract to screen and test potential endocrine disruptors. Results are presented from a validation of the assay in Japan in which seven laboratories determined doseresponses of methyltestosterone, vinclozolin, and p,p'-DDE. Five laboratories used CrJ:CD SpragueDawley castrated rats, and two used Brl Han: WIST Jcl castrated rats. Each test chemical was administered orally via a stomach tube for ten consecutive days. Results reveal that the weights of all the accessory sex organs from the experimental animals in all laboratories exhibited significant dose-related changes in the assays, and the normalized doseresponse curves showed that all five tissues-the ventral prostate, the seminal vesicles with coagulating glands, the levator ani and bulbocavernosus muscle complex, the Cowper's glands, and the glans penis-reacted in a similar manner for each compound. Overall, the Hershberger assay was determined to be a good screening assay for detecting the androgen agonistic and antagonistic effects of chemicals. JF - Environmental Health Perspectives AU - Yamasaki, Kanji AU - Sawaki, Masakuni AU - Ohta, Ryo AU - Okuda, Hirokazu AU - Katayama, Seiichi AU - Yamada, Yomoya AU - Ohta, Takafumi Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1912 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSE RESPONSE PROFILES KW - CHEMICAL ANALYSIS KW - HORMONAL EFFECTS KW - BIOASSAY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14678313?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=OECD+Validation+of+the+Hershberger+Assay+in+Japan%3A+Phase+2+Dose+Response+of+Methyltestosterone%2C+Vinclozolin%2C+and+p%2Cp%27-DDE&rft.au=Yamasaki%2C+Kanji%3BSawaki%2C+Masakuni%3BOhta%2C+Ryo%3BOkuda%2C+Hirokazu%3BKatayama%2C+Seiichi%3BYamada%2C+Yomoya%3BOhta%2C+Takafumi&rft.aulast=Yamasaki&rft.aufirst=Kanji&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1912&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 15 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; CHEMICAL ANALYSIS; HORMONAL EFFECTS; BIOASSAY ER - TY - JOUR T1 - Effect of Endosulfan on Male Reproductive Development AN - 14678249; 10654835 AB - Schoolchildren who were permanent residents of a village situated below cashew plantations that had been sprayed aerially with endosulfan over a number of years were used as an endosulfan-exposed population, and a control population was selected from schoolchildren of another village located approximately 20 km away. The exposed village had 12 first-order streams originating from the cashew plantation. The two groups were used to examine the effect of endosulfan on male reproductive development. Serum levels of testosterone, luteinizing hormone, follicle-stimulating hormone, and endosulfan residues were estimated. Significantly lower sexual maturity rating scores and serum testosterone levels were found in the study group, along with higher levels of serum luteinizing hormone, compared with controls. The levels of endosulfan in the study group children were significantly higher than those in control children, with mean endosulfan levels of 7.47 and 1.37 ppb, respectively. JF - Environmental Health Perspectives AU - Saiyed, Habibullah AU - Dewan, Aruna AU - Bhatnagar, Vijay AU - Shenoy, Udyavar AU - Shenoy, Rathika AU - Rajmohan, Hirehall AU - Patel, Kumud Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1958 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - INSECTICIDE EXPOSURE KW - HORMONAL EFFECTS KW - ENDOSULFAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14678249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+of+Endosulfan+on+Male+Reproductive+Development&rft.au=Saiyed%2C+Habibullah%3BDewan%2C+Aruna%3BBhatnagar%2C+Vijay%3BShenoy%2C+Udyavar%3BShenoy%2C+Rathika%3BRajmohan%2C+Hirehall%3BPatel%2C+Kumud&rft.aulast=Saiyed&rft.aufirst=Habibullah&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1958&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; INSECTICIDE EXPOSURE; HORMONAL EFFECTS; ENDOSULFAN ER - TY - JOUR T1 - Strategies for Setting a National Research Agenda That Is Responsive to Community Needs AN - 14678183; 10654819 AB - In the area of national environmental health research, funding and research institutions must be proactive in building partnerships with communities so that research program development is congruent with the concerns and public-health needs of communities. In community-based participation, communities benefit from policy change, improved health, capacity building, and jobs created through the project, while researchers benefit with increased participation and retention of community residents. In an effort to foster such relationships, NIEHS developed Environmental Justice: Partnerships for Communication in 1993, which uses various strategies, including workshops, retreats, community advisory groups, and town meetings, to develop a national environmental health research agenda that is responsive to community concerns. Each component of the agenda is described, along with the lessons learned along the way. JF - Environmental Health Perspectives AU - O'Fallon, Liam R AU - Wolfle, Geraldine M AU - Brown, David AU - Dearry, Allen AU - Olden, Kenneth Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1855 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - US NATIONAL INSTITUTE OF ENV HEALTH SCIENCES KW - PUBLIC HEALTH KW - PUBLIC PARTICIPATION KW - EDUCATION, PUBLIC KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14678183?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Strategies+for+Setting+a+National+Research+Agenda+That+Is+Responsive+to+Community+Needs&rft.au=O%27Fallon%2C+Liam+R%3BWolfle%2C+Geraldine+M%3BBrown%2C+David%3BDearry%2C+Allen%3BOlden%2C+Kenneth&rft.aulast=O%27Fallon&rft.aufirst=Liam&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1855&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - US NATIONAL INSTITUTE OF ENV HEALTH SCIENCES; PUBLIC HEALTH; PUBLIC PARTICIPATION; EDUCATION, PUBLIC ER - TY - JOUR T1 - Silica Exposure and Systemic Vasculitis AN - 14677832; 10654831 AB - The case is presented of a 63-yr-old white male who had worked formerly at LANL where he had been exposed, as a weapons-testing technician, to silica, beryllium, various solvents, heavy metals, depleted uranium, and ionizing radiation. The work history of the subject is described, along with his disease progression, which included microscopic polyangiitis, systemic necrotizing valculitis, leukocytoclastic vasculitis, pulmonary interstitial fibrosis, and glomerulonephritis. JF - Environmental Health Perspectives AU - Mulloy, Karen B Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1933 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - MEDICAL SURVEILLANCE KW - US LOS ALAMOS SCIENTIFIC LABORATORY KW - DISEASES AND DISORDERS KW - SILICON COMPOUNDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677832?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Silica+Exposure+and+Systemic+Vasculitis&rft.au=Mulloy%2C+Karen+B&rft.aulast=Mulloy&rft.aufirst=Karen&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1933&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t maps N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; US LOS ALAMOS SCIENTIFIC LABORATORY; MEDICAL SURVEILLANCE; DISEASES AND DISORDERS; SILICON COMPOUNDS ER - TY - JOUR T1 - Profile of Urinary Arsenic Metabolites During Pregnancy AN - 14677767; 10654824 AB - Arsenic species were measured in sequential urine samples obtained during pregnancy from women in Chile exposed to moderately elevated As levels in drinking water. The urine samples were collected four times, covering most of the second half of pregnancy. The mean total As levels exhibited a clear increasing trend across pregnancy, and the creatinine-adjusted values showed a similar trend, although with an even steeper gradient. The mean proportion of inorganic As decreased by 44.1% from the first to the fourth urine sample, and the proportion of monomethylarsenate (MMA) also decreased steadily, while the proportion of dimethylarsenate (DMA) increased correspondingly, which resulted in a decrease of the MMA:DMA ratio. Most of the change in the relative distribution of metabolites was due to the increase in DMA. JF - Environmental Health Perspectives AU - Hopenhayn, Claudia AU - Huang, Bin AU - Christian, Jay AU - Peralta, Cecilia AU - Ferreccio, Catterina AU - Atallah, Raja AU - Kalman, David Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1888 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHILE KW - ARSENIC KW - PREGNANCY KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Profile+of+Urinary+Arsenic+Metabolites+During+Pregnancy&rft.au=Hopenhayn%2C+Claudia%3BHuang%2C+Bin%3BChristian%2C+Jay%3BPeralta%2C+Cecilia%3BFerreccio%2C+Catterina%3BAtallah%2C+Raja%3BKalman%2C+David&rft.aulast=Hopenhayn&rft.aufirst=Claudia&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1888&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHILE; ARSENIC; PREGNANCY; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Effect of Bisphenol A on Murine Immune Function: Modulation of Interferon- gamma , IgG2a, and Disease Symptoms in NZB NZW F sub(1) Mice AN - 14677404; 10654823 AB - Female NZB NZW F sub(1) mice spontaneously develop a disease comparable with human lupus, displaying glomerulonephritis, arthritis, and elevated levels of immunoglobulin (IgG) autoantibodies. To determine the effects of bisphenol A in a lupus model, bisphenol A was fed to five-week-old NZB/NZW mice and to the non-autoimmune C57BL/6 strain, and the following parameters were analyzed: interferon- gamma and interleukin-10 release, IgG2a antibody production, and the development of proteinuria. An inhibitory effect of bisphenol A was observed on interferon- gamma secretion in both male and female C57BL/6 and female NZB/NZW mice. In the lupus-prone mice, bisphenol A acted in a protective manner, also reducing IgG2a antibody production from lipopolysaccharide-stimulated splenocytes and delaying the onset of proteinuria. JF - Environmental Health Perspectives AU - Sawai, Catherine AU - Anderson, Katherine AU - Walser-Kuntz, Debby Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1883 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DISEASES AND DISORDERS KW - PHYSIOLOGICAL RESPONSES, ANIMAL KW - HORMONES KW - IMMUNE RESPONSE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677404?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+of+Bisphenol+A+on+Murine+Immune+Function%3A+Modulation+of+Interferon-+gamma+%2C+IgG2a%2C+and+Disease+Symptoms+in+NZB+%26lt%3BMB%26gt%3B+NZW+F+sub%281%29+Mice&rft.au=Sawai%2C+Catherine%3BAnderson%2C+Katherine%3BWalser-Kuntz%2C+Debby&rft.aulast=Sawai&rft.aufirst=Catherine&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1883&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; PHYSIOLOGICAL RESPONSES, ANIMAL; HORMONES; IMMUNE RESPONSE ER - TY - JOUR T1 - Flavonoids as Aryl Hydrocarbon Receptor Agonists/Antagonists: Effects of Structure and Cell Context AN - 14677350; 10654822 AB - The aryl hydrocarbon-receptor agonist/antagonist activities of a number of phytochemicals were investigated and compared to TCDD. The compounds included: chrysin, phloretin, kaempferol, galangin, naringenin, genistein, quercetin, myricetin, luteolin, baicalein, daidzein, apigenin, and diosmin, as well as cantharidin and emodin. Three cell lines were used: MCF-7 human breast cells, HepG2 human liver cancer cells, and stably transfected mouse Hepa-1 cells. Results showed that several structurally diverse phytochemicals and catharidin activated dioxin-responsive-element-dependent luciferase activity in the cell lines. Results indicated that TCDD, chrysin, and baicalein induced luciferase activity in all three cell lines, while cantharidin induced luciferase activity only in the human cells, and emodin was active in Hepa-1 and MCF-7 cells. Galangin, genistein, daidzein, apigenin, and diosmin were active only in stably transfected Hepa-1 cells. The stably transfected mouse Hepa-1 cell line was more sensitive than the transiently transfected human MCF-7 and HepG2 cells to TCDD and to most of the phytochemicals. JF - Environmental Health Perspectives AU - Zhang, Shu AU - Qin, Chunhua AU - Safe, Stephen H Y1 - 2003/12// PY - 2003 DA - Dec 2003 SP - 1877 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CYTOTOXICITY KW - PLANTS, BIOLOGIC KW - TETRACHLORODIBENZODIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677350?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Flavonoids+as+Aryl+Hydrocarbon+Receptor+Agonists%2FAntagonists%3A+Effects+of+Structure+and+Cell+Context&rft.au=Zhang%2C+Shu%3BQin%2C+Chunhua%3BSafe%2C+Stephen+H&rft.aulast=Zhang&rft.aufirst=Shu&rft.date=2003-12-01&rft.volume=111&rft.issue=16&rft.spage=1877&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CYTOTOXICITY; PLANTS, BIOLOGIC; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Pressurised liquid extraction--comprehensive two-dimensional gas chromatography for fast-screening of polycyclic aromatic hydrocarbons in soil. AN - 71412272; 14650617 AB - Pressurised liquid extraction (PLE) was applied to the extraction of polycyclic aromatic hydrocarbons (PAHs) from contaminated soils from Husarviken in Stockholm, Sweden. The extraction step was followed by conventional gas chromatography (GC), comprehensive two-dimensional gas chromatography (GC x GC) (both with flame ionisation detection) and gas chromatography-quadrupole mass spectrometry (GC-MS) analysis. Qualitative and quantitative aspects of the results are considered. Qualitatively, results from all chromatographic analyses are in good agreement, and PLE provides a reliable extraction technique with all PAHs extracted in one extraction step; no carry over was observed. With respect to PAH quantification, some variability in results was noted, with better agreement in PAH concentrations for GC and GC x GC measurement, as compared to GC-MS. GC analysis compares favourably with GC x GC apart from the few exceptions where peaks are not fully resolved from other co-extracted analytes, which compromises GC-FID measurement. For example, acenaphthene shows a much higher concentration when measured by GC-FID, demonstrating the superior separating powers of GC x GC; the latter is the preferred technique if precise and accurate quantification of analytes are required. GC-MS results compare reasonably with GC x GC for low-molecular mass PAHs but not for high-molecular mass PAHs; results for GC-MS are consistently higher than those for GC x GC for high-molecular mass PAHs. Since PLE-GC x GC is proposed as a broad screening tool, the demand for precise quantification may be relaxed in the present situation. GC x GC has the added advantage of providing chemical structural information within the two-dimensional contour presentation. Reproducibilities for GC x GC results (peak area) and 2tR were acceptable with relative standard deviations (R.S.D.) of 8 and 1%, respectively (at the mg/kg level), and good repeatability within samples was achieved. JF - Journal of chromatography. A AU - Ong, Ruby AU - Lundstedt, Staffan AU - Haglund, Peter AU - Marriott, Philip AD - Australian Centre for Research on Separation Science, RMIT University, GPO Box 2476V, Melbourne 3001, Australia. Y1 - 2003/11/26/ PY - 2003 DA - 2003 Nov 26 SP - 221 EP - 232 VL - 1019 IS - 1-2 SN - 0021-9673, 0021-9673 KW - Polycyclic Compounds KW - 0 KW - Soil Pollutants KW - Index Medicus KW - Reproducibility of Results KW - Reference Standards KW - Mass Spectrometry -- methods KW - Polycyclic Compounds -- analysis KW - Chromatography, Gas -- methods KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71412272?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chromatography.+A&rft.atitle=Pressurised+liquid+extraction--comprehensive+two-dimensional+gas+chromatography+for+fast-screening+of+polycyclic+aromatic+hydrocarbons+in+soil.&rft.au=Ong%2C+Ruby%3BLundstedt%2C+Staffan%3BHaglund%2C+Peter%3BMarriott%2C+Philip&rft.aulast=Ong&rft.aufirst=Ruby&rft.date=2003-11-26&rft.volume=1019&rft.issue=1-2&rft.spage=221&rft.isbn=&rft.btitle=&rft.title=Journal+of+chromatography.+A&rft.issn=00219673&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-07-21 N1 - Date created - 2003-12-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Potential roles of P-gp and calcium channels in loperamide and diphenoxylate transport AN - 19219370; 5785038 AB - This study examined the accumulation and transport of two related systemic opioids used as antidiarrhoeal drugs and compared their rates of transport with known P-glycoprotein (P-gp) substrates used in our in vitro environment. Cellular uptake and efflux and transcellular transport were all determined using Caco-2 cells after exposure to loperamide or diphenoxylate, with or without a range of efflux inhibitors. Bidirectional transport studies of 5 mu M loperamide showed efflux to be fivefold higher than influx (42 10 super(-6) compared to 8 10 super(-6) cm/s); however, this decreased to twofold at 10 mu M and was abolished using 100 mu M loperamide. An uptake pathway was also discovered when P-gp was inhibited which, in the presence of Ca super(2+) channel blockers, was amplified, providing a potential mechanism for central nervous system effects to be increased upon blockage of L-type calcium channels, quite separate from any P-gp inhibition. Diphenoxylate transport, however, showed little sign of P-gp-mediated efflux. Diphenoxylate accumulated readily within cells, yet transport through cells was very low. Additionally, efflux inhibitors had little impact on transport or accumulation, suggesting that diphenoxylate was not a substrate for an efflux mechanism. JF - Toxicology and Applied Pharmacology AU - Crowe, A AU - Wong, P AD - School of Pharmacy, Curtin University of Technology, GPO Box U1987, Perth, Western Australia, 6845, Australia, A.P.Crowe@curtin.edu.au Y1 - 2003/11/15/ PY - 2003 DA - 2003 Nov 15 SP - 127 EP - 137 PB - Elsevier Inc. VL - 193 IS - 1 SN - 0041-008X, 0041-008X KW - calcium channels KW - diphenoxylate KW - loperamide KW - Toxicology Abstracts KW - P-Glycoprotein KW - Transport KW - Opioids KW - X 24117:Biochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19219370?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Potential+roles+of+P-gp+and+calcium+channels+in+loperamide+and+diphenoxylate+transport&rft.au=Crowe%2C+A%3BWong%2C+P&rft.aulast=Crowe&rft.aufirst=A&rft.date=2003-11-15&rft.volume=193&rft.issue=1&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2FS0041-008X%2803%2900372-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Transport; P-Glycoprotein; Opioids DO - http://dx.doi.org/10.1016/S0041-008X(03)00372-7 ER - TY - JOUR T1 - Deep vein thrombosis and air travel: record linkage study AN - 17888934; 5854348 AB - Objective To investigate the time relations between long haul air travel and venous thromboembolism. Design Record linkage study using the case crossover approach. Setting Western Australia. Participants 5408 patients admitted to hospital with venous thromboembolism and matched with data for arrivals of international flights during 1981-99. Results The risk of venous thromboembolism is increased for only two weeks after a long haul flight; 46 Australian citizens and 200 non-Australian citizens had an episode of venous thromboembolism during this so called hazard period. The relative risk during this period for Australian citizens was 4.17 (95% confidence interval, 2.94 to 5.40), with 76% of cases (n = 35) attributable to the preceding flight. A "healthy traveller" effect was observed, particularly for Australian citizens. Conclusions The annual risk of venous thromboembolism is increased by 12% if one long haul flight is taken yearly. The average risk of death from flight related venous thromboembolism is small compared with that from motor vehicle crashes and injuries at work. The individual risk of death from flight related venous thromboembolism for people with certain pre-existing medical conditions is, however, likely to be greater than the average risk of 1 per 2 million for passengers arriving from a flight. Airlines and health authorities should continue to advise passengers on how to minimise risk. JF - British Medical Journal AU - Kelman, C W AU - Kortt, MA AU - Becker, NG AU - Li, Z AU - Mathews, J D AU - Guest, C S AU - Holman, CDJ AD - Commonwealth Department of Health and Ageing, GPO Box 9848, Canberra, ACT 2601, Australia, christopher.kelman@health.gov.au Y1 - 2003/11/08/ PY - 2003 DA - 2003 Nov 08 SP - 1072 EP - 1074 VL - 327 IS - 7423 SN - 0959-8138, 0959-8138 KW - thromboembolism KW - Health & Safety Science Abstracts; Risk Abstracts KW - Risk assessment KW - Travel KW - Hazards KW - Aircraft KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17888934?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=British+Medical+Journal&rft.atitle=Deep+vein+thrombosis+and+air+travel%3A+record+linkage+study&rft.au=Kelman%2C+C+W%3BKortt%2C+MA%3BBecker%2C+NG%3BLi%2C+Z%3BMathews%2C+J+D%3BGuest%2C+C+S%3BHolman%2C+CDJ&rft.aulast=Kelman&rft.aufirst=C&rft.date=2003-11-08&rft.volume=327&rft.issue=7423&rft.spage=1072&rft.isbn=&rft.btitle=&rft.title=British+Medical+Journal&rft.issn=09598138&rft_id=info:doi/10.1136%2Fbmj.327.7423.1072 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Travel; Hazards; Aircraft; Risk assessment DO - http://dx.doi.org/10.1136/bmj.327.7423.1072 ER - TY - JOUR T1 - An environmental approach for used oil management in Asian cities: a Bangkok' s experience. AN - 71528196; 14758889 AB - This paper addresses increasing concern about the pollution threat of used oil being illegally dumped and the impact of oil on air pollution and freshwater ecosystems in Asian countries. Used oil is a very serious waste management problem. These results call for management action such as maximising the collection and recovery of used oil. The Thai government recognizes the need to recycle used oil and has been active in encouraging programs to accomplish this goal. Thus unless new approaches and incentives are developed, used oil generation may become an increasing serious problem to our environment. The purpose of this study is to examine the technical and economic feasibility, of recycling used oils. In addition, this paper briefly discusses the problems to be overcome and outlines potential mechanisms for providing the necessary disposal controls in order to maximize the protection to public health and environmental quality from potential hazards posed by used lube oil disposal. JF - Journal of environmental sciences (China) AU - Leong, Shing Tet AU - Laortanakul, Preecha AD - Urban Environmental Engineering and Management Program, School of Environment, Resources and Development, Asian Institute of Technology, GPO Box 4, Klong Luang, Pathumthani 12120, Thailand. tet@ait.ac.th Y1 - 2003/11// PY - 2003 DA - November 2003 SP - 734 EP - 743 VL - 15 IS - 6 SN - 1001-0742, 1001-0742 KW - Fuel Oils KW - 0 KW - Index Medicus KW - Cities KW - Government Regulation KW - Thailand KW - Conservation of Natural Resources -- methods KW - Industry KW - Environmental Pollution -- prevention & control KW - Waste Disposal, Fluid -- legislation & jurisprudence KW - Industrial Oils -- analysis KW - Fuel Oils -- analysis KW - Environmental Pollution -- legislation & jurisprudence KW - Waste Disposal, Fluid -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71528196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+sciences+%28China%29&rft.atitle=An+environmental+approach+for+used+oil+management+in+Asian+cities%3A+a+Bangkok%27+s+experience.&rft.au=Leong%2C+Shing+Tet%3BLaortanakul%2C+Preecha&rft.aulast=Leong&rft.aufirst=Shing&rft.date=2003-11-01&rft.volume=15&rft.issue=6&rft.spage=734&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+sciences+%28China%29&rft.issn=10010742&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-07 N1 - Date created - 2004-02-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Cyclooxygenase-2 inhibitors: are they really atherothrombotic, and if not, why not? AN - 71347624; 14576372 AB - BACKGROUND AND SUMMARY: Selective cyclooxygenase (COX)-2 inhibitors are increasingly being used in place of "conventional" nonsteroidal anti-inflammatory drugs (NSAIDs). This is because they are just as effective as NSAIDs in relieving arthritic pain and yet less gastrotoxic. However, the cardiovascular safety of selective COX-2 inhibitors has been questioned because they selectively reduce prostacyclin production, thus disrupting the normal homeostatic balance and promoting a prothrombotic state. These theoretical concerns appear to be supported by the results of clinical trials demonstrating an increased risk of myocardial infarction with COX-2 inhibitors compared with a conventional NSAID, and indirect comparisons of the rates of myocardial infarction among patients treated with a selective COX-2 inhibitor compared with aspirin in different trials. However, emerging data from animal, experimental and clinical studies suggest that COX-2 is atherogenic and thrombogenic, and that selective COX-2 inhibitors may be cardioprotective. Meta-analyses of randomized trials of selective COX-2 inhibitors compared with placebo have demonstrated no excess of cardiovascular events among patients allocated COX-2 inhibitors, and preliminary data from a randomized controlled trial of the selective COX-2 inhibitor meloxicam, in patients with acute coronary syndrome who were treated with aspirin, demonstrated a reduction in cardiovascular events among patients allocated the COX-2 inhibitor. Continuing uncertainty regarding the direction and magnitude of any cardiovascular effects of selective COX-2 inhibitors, coupled with their widespread and increasing use, mandates prospective randomized evaluation of their efficacy and safety in patients at increased risk of future cardiovascular events. JF - Stroke AU - Hankey, Graeme J AU - Eikelboom, John W AD - Stroke Unit, Department of Neurology, Royal Perth Hospital, Box X2213 GPO, Perth, WA 6001, Australia. gjhankey@cyllene.uwa.edu.au Y1 - 2003/11// PY - 2003 DA - November 2003 SP - 2736 EP - 2740 VL - 34 IS - 11 KW - Anti-Inflammatory Agents, Non-Steroidal KW - 0 KW - Cyclooxygenase Inhibitors KW - Epoprostenol KW - DCR9Z582X0 KW - Index Medicus KW - Animals KW - Humans KW - Anti-Inflammatory Agents, Non-Steroidal -- adverse effects KW - Epoprostenol -- metabolism KW - Arthritis -- drug therapy KW - Risk Assessment KW - Clinical Trials as Topic -- statistics & numerical data KW - Thrombosis -- chemically induced KW - Cyclooxygenase Inhibitors -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71347624?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Stroke&rft.atitle=Cyclooxygenase-2+inhibitors%3A+are+they+really+atherothrombotic%2C+and+if+not%2C+why+not%3F&rft.au=Hankey%2C+Graeme+J%3BEikelboom%2C+John+W&rft.aulast=Hankey&rft.aufirst=Graeme&rft.date=2003-11-01&rft.volume=34&rft.issue=11&rft.spage=2736&rft.isbn=&rft.btitle=&rft.title=Stroke&rft.issn=1524-4628&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-11-25 N1 - Date created - 2003-11-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Torsade de pointes associated with the administration of intravenous haloperidol:a review of the literature and practical guidelines for use. AN - 71322529; 14585064 AB - Haloperidol is the most commonly used medication for the treatment of delirium and psychosis in the critically ill patient. Whilst generally considered to be safe, haloperidol has been associated with a number of important cardiovascular side effects. The major toxicities include hypotension, cardiac arrhythmias and prolongation of the corrected QT (QTc) interval. In particular, torsade de pointes, a polymorphic ventricular tachyarrhythmia, has been associated with both intravenous and oral haloperidol administration. The management of torsade de pointes consists of discontinuation of the possible offending agent(s), correction of electrolyte abnormalities, administration of magnesium sulfate and, if necessary, overdrive pacing. Although clinicians should be aware of this potentially lethal complication of intravenous haloperidol therapy, it should not deter clinicians from using intravenous haloperidol to treat acute agitation in the critically ill patient with a normal QTc. JF - Expert opinion on drug safety AU - Hassaballa, Hesham A AU - Balk, Robert A AD - Division of Pulmonary and Critical Care Medicine, Rush-Presbyterian St Luke's Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA. Y1 - 2003/11// PY - 2003 DA - November 2003 SP - 543 EP - 547 VL - 2 IS - 6 SN - 1474-0338, 1474-0338 KW - Antipsychotic Agents KW - 0 KW - Magnesium Sulfate KW - 7487-88-9 KW - Haloperidol KW - J6292F8L3D KW - Index Medicus KW - Injections, Intravenous KW - Dose-Response Relationship, Drug KW - Humans KW - Practice Guidelines as Topic KW - Magnesium Sulfate -- therapeutic use KW - Haloperidol -- adverse effects KW - Antipsychotic Agents -- administration & dosage KW - Haloperidol -- administration & dosage KW - Torsades de Pointes -- chemically induced KW - Antipsychotic Agents -- adverse effects KW - Torsades de Pointes -- therapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71322529?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+opinion+on+drug+safety&rft.atitle=Torsade+de+pointes+associated+with+the+administration+of+intravenous+haloperidol%3Aa+review+of+the+literature+and+practical+guidelines+for+use.&rft.au=Hassaballa%2C+Hesham+A%3BBalk%2C+Robert+A&rft.aulast=Hassaballa&rft.aufirst=Hesham&rft.date=2003-11-01&rft.volume=2&rft.issue=6&rft.spage=543&rft.isbn=&rft.btitle=&rft.title=Expert+opinion+on+drug+safety&rft.issn=14740338&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-04-07 N1 - Date created - 2003-10-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Prospects for Mexican Federalism: Roots of the Policy Issues AN - 60675667; 200406146 AB - Explores Mexico's long history of debate over federalism, its longstanding inability to implement such a system, & recent signs of change. The former president of Mexico, Ernesto Zedillo, was instrumental in implementing reforms that provided for fair electoral procedures in individual states & that gave power to the judiciary to police elections. These changes helped to achieve the defeat of the PRI & the election of President Vicente Fox. Federalism & the dispersion of power are now evidenced through direct elections, governors from opposition parties, & significant opposition representation in the federal legislature. Worries about federalism include the fear that personalismo may dominate local government & that chaos & dissidence will follow the establishment of federalism. Chiapas, Guerrero, Michoacan, Oaxaca, Hidalgo, Puebla, & Chihuahua are currently showing signs of the disintegration of authority. L. A. Hoffman JF - Policy Studies Journal AU - Merchant, David AU - Rich, Paul AD - Library of Congress Y1 - 2003/11// PY - 2003 DA - November 2003 SP - 661 EP - 667 VL - 31 IS - 4 SN - 0190-292X, 0190-292X KW - Elections KW - Mexico KW - Political History KW - Federalism KW - Political Power KW - article KW - 9087: government/political systems; state and local governments/political systems KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60675667?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Policy+Studies+Journal&rft.atitle=Prospects+for+Mexican+Federalism%3A+Roots+of+the+Policy+Issues&rft.au=Merchant%2C+David%3BRich%2C+Paul&rft.aulast=Merchant&rft.aufirst=David&rft.date=2003-11-01&rft.volume=31&rft.issue=4&rft.spage=661&rft.isbn=&rft.btitle=&rft.title=Policy+Studies+Journal&rft.issn=0190292X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - PSJOD9 N1 - SubjectsTermNotLitGenreText - Mexico; Federalism; Elections; Political History; Political Power ER - TY - JOUR T1 - Foreign economic policy, 1969-1972 AN - 37806457; 2753849 JF - Diplomatic history AU - Matusow, Allen J AU - Matusow, Allen J Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 767 EP - 772 PB - U.S. Government Printing Office VL - 27 IS - 5 SN - 0145-2096, 0145-2096 KW - Political Science KW - International relations KW - Foreign policy KW - Foreign economic policy KW - History KW - Politics KW - Economics KW - History of international relations KW - U.S.A. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37806457?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Diplomatic+history&rft.atitle=Foreign+economic+policy%2C+1969-1972&rft.au=Matusow%2C+Allen+J&rft.aulast=Matusow&rft.aufirst=Allen&rft.date=2003-11-01&rft.volume=27&rft.issue=5&rft.spage=767&rft.isbn=&rft.btitle=&rft.title=Diplomatic+history&rft.issn=01452096&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 5176 6722 3977 5574 10472; 5200 5574 10472; 4025; 9809; 6784; 5906 6784; 5889; 433 293 14 ER - TY - JOUR T1 - Foreign relations of the United States, 1969-1976 AN - 37806285; 2753848 JF - Diplomatic history AU - Matusow, Allen J AU - Matusow, Allen J Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 767 EP - 772 PB - U.S. Government Printing Office VL - 27 IS - 5 SN - 0145-2096, 0145-2096 KW - Political Science KW - International relations KW - Foreign policy KW - History KW - Diplomacy KW - History of international relations KW - U.S.A. KW - Foreign relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37806285?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Diplomatic+history&rft.atitle=Foreign+relations+of+the+United+States%2C+1969-1976&rft.au=Matusow%2C+Allen+J&rft.aulast=Matusow&rft.aufirst=Allen&rft.date=2003-11-01&rft.volume=27&rft.issue=5&rft.spage=767&rft.isbn=&rft.btitle=&rft.title=Diplomatic+history&rft.issn=01452096&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Volume 3 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 5205; 5200 5574 10472; 3564 6784; 6784; 5906 6784; 5889; 433 293 14 ER - TY - JOUR T1 - International monetary policy, 1969-1972 AN - 37805769; 2753850 JF - Diplomatic history AU - Matusow, Allen J AU - Matusow, Allen J Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 767 EP - 772 PB - U.S. Government Printing Office VL - 27 IS - 5 SN - 0145-2096, 0145-2096 KW - Political Science KW - International relations KW - Foreign economic policy KW - History KW - Economics KW - International monetary policy KW - History of international relations KW - U.S.A. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37805769?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Diplomatic+history&rft.atitle=International+monetary+policy%2C+1969-1972&rft.au=Matusow%2C+Allen+J&rft.aulast=Matusow&rft.aufirst=Allen&rft.date=2003-11-01&rft.volume=27&rft.issue=5&rft.spage=767&rft.isbn=&rft.btitle=&rft.title=Diplomatic+history&rft.issn=01452096&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 6784; 6763 6722 3977 5574 10472 8217; 5176 6722 3977 5574 10472; 4025; 5906 6784; 5889; 433 293 14 ER - TY - JOUR T1 - Delay in diagnosis: how do patients feel? [Delays in diagnosing cancer: threat to the patient-physician relationship? 2003;49:857-859] AN - 205192860 JF - Canadian Family Physician AU - Dawes, CRS AU - Walker, Vivian Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1439 CY - Mississauga PB - College of Family Physicians of Canada VL - 49 SN - 0008350X KW - Medical Sciences KW - Physician patient relationships KW - Medical diagnosis KW - Family medicine KW - Sisler, Jeffrey J KW - 9172:Canada UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/205192860?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apqrl&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Canadian+Family+Physician&rft.atitle=Delay+in+diagnosis%3A+how+do+patients+feel%3F+%5BDelays+in+diagnosing+cancer%3A+threat+to+the+patient-physician+relationship%3F+2003%3B49%3A857-859%5D&rft.au=Dawes%2C+CRS%3BWalker%2C+Vivian&rft.aulast=Dawes&rft.aufirst=CRS&rft.date=2003-11-01&rft.volume=49&rft.issue=&rft.spage=1439&rft.isbn=&rft.btitle=&rft.title=Canadian+Family+Physician&rft.issn=0008350X&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright College of Family Physicians of Canada Nov 2003 N1 - People - Sisler, Jeffrey J N1 - Last updated - 2012-02-09 N1 - SubjectsTermNotLitGenreText - Sisler, Jeffrey J ER - TY - JOUR T1 - A novel methylthio metabolite of s-triazolo[3, 4-a]phthalazine, a lead compound for the development of antianxiety drugs, in rats AN - 19952026; 5745478 AB - When s-triazolo[3, 4-a]phthalazine (Tri-P) was orally administered in rats, a more lipophilic metabolite M-1 than the parent compound was isolated from the urine. The metabolite M-1 was identified as 7-methylthio Tri-P by means of high resolution MS and two-dimentional NMR spectrometry. Furthermore, the 7- methylthio conjugate was generated from the parent compound Tri-P in isolated rat hepatocytes. Although the contribution of the intestinal microflora to the formation of methylthio metabolite has been pointed out so far, the limited data in this study lead us to conclude that the liver plays a role in all metabolic reactions of Tri-P to its 7-methylthio conjugate in rats. JF - Life Sciences AU - Imamura, Y AU - Noda, A AU - Imamura, T AU - Ono, Y AU - Okawara, T AU - Noda, H AD - Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1, Oe-honmachi, Kumamoto 862-0973, Japan, yorishig@gpo.kumamoto-u.ac.jp Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 29 EP - 36 PB - Elsevier Science Inc., Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 74 IS - 1 SN - 0024-3205, 0024-3205 KW - Biotechnology and Bioengineering Abstracts KW - s-Triazolo[3, 4-a]phthalazine KW - Methylthio conjugate KW - Lipophilic metabolite KW - Rat urine KW - Rat hepatocytes KW - Intestinal microflora KW - Data processing KW - Urine KW - Hepatocytes KW - Magnetic resonance spectroscopy KW - Liver KW - Oral administration KW - Metabolites KW - Drug development KW - Lipophilic KW - W 30910:Imaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19952026?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Life+Sciences&rft.atitle=A+novel+methylthio+metabolite+of+s-triazolo%5B3%2C+4-a%5Dphthalazine%2C+a+lead+compound+for+the+development+of+antianxiety+drugs%2C+in+rats&rft.au=Imamura%2C+Y%3BNoda%2C+A%3BImamura%2C+T%3BOno%2C+Y%3BOkawara%2C+T%3BNoda%2C+H&rft.aulast=Imamura&rft.aufirst=Y&rft.date=2003-11-01&rft.volume=74&rft.issue=1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Life+Sciences&rft.issn=00243205&rft_id=info:doi/10.1016%2Fj.lfs.2003.06.032 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Intestinal microflora; Data processing; Hepatocytes; Urine; Magnetic resonance spectroscopy; Oral administration; Liver; Drug development; Metabolites; Lipophilic DO - http://dx.doi.org/10.1016/j.lfs.2003.06.032 ER - TY - JOUR T1 - The influence of visual feedback on power during leg press on elite women field hockey players AN - 19226558; 5784202 AB - Objective. The purpose of this study is to investigate the influences of visual feedback on power performance during leg press. Design. The research was conducted as an experimental procedure with a cross-over design. Setting, participants and main outcome measures. Sixteen, elite, female, field hockey players aged 16-27 years were randomly assigned to two groups. Both groups were tested with and without visual feedback, but in the reverse order. The test protocol consisted of familiarisation followed by two test trials. The visual feedback was produced by and displayed on a computer that was used to record the power output. Results. Power performance was significantly better with visual feedback than without visual feedback (p=0.027). There was no significant interaction between the testing order, suggesting no carry over effect (p=0.212). Conclusion. Visual feedback has a significant positive effect on the power performance of elite, female, field hockey players using a leg press. JF - Physical Therapy in Sport AU - Hopper, D M AU - Berg, Axel, MA AU - Andersen, H AU - Madan, R AD - School of Physiotherapy, Curtin University of Technology, GPO Box 1987, Perth,WA 6845, Australia, d.hopper@curtin.edu.au Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 182 EP - 186 VL - 4 IS - 4 SN - 1466-853X, 1466-853X KW - Physical Education Index KW - Field hockey KW - Physical therapy KW - Athletes (elite) KW - Athletes (women) KW - Feedback KW - PE 110:Physical Therapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19226558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Physical+Therapy+in+Sport&rft.atitle=The+influence+of+visual+feedback+on+power+during+leg+press+on+elite+women+field+hockey+players&rft.au=Hopper%2C+D+M%3BBerg%2C+Axel%2C+MA%3BAndersen%2C+H%3BMadan%2C+R&rft.aulast=Hopper&rft.aufirst=D&rft.date=2003-11-01&rft.volume=4&rft.issue=4&rft.spage=182&rft.isbn=&rft.btitle=&rft.title=Physical+Therapy+in+Sport&rft.issn=1466853X&rft_id=info:doi/10.1016%2FS1466-853X%2803%2900068-3 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Physical therapy; Field hockey; Athletes (elite); Athletes (women); Feedback DO - http://dx.doi.org/10.1016/S1466-853X(03)00068-3 ER - TY - JOUR T1 - Differential transcriptional activation of select metabolic genes in response to variations in exercise intensity and duration AN - 19197233; 5780106 AB - Cellular adaptations to endurance training are influenced by the intensity and duration of exercise. To examine the impact of exercise intensity and duration on the acute transcriptional regulation of metabolic genes in red (RG) and white (WG) gastrocnemius muscle, rats completed either low-intensity [ similar to 50% maximal O sub(2) uptake (Vo sub(2 max))] treadmill exercise (LIE) for 45 min, LIE for 180 min, or high-intensity ( similar to 75% Vo sub(2 max)) exercise (HIE) for 45 min. LIE for 45 min activated (P 30-fold) and HKII transcription (>25-fold). In WG, extending LIE for 180 min induced a much greater and prolonged (through 2- to 4-h recovery) activation of PDK4, UCP3 (both >200-fold), and HO-1 (>10-fold). HIE elicited a similar pattern of gene activation to LIE in both RG and WG, with the exception that HIE triggered >10-fold activation of HO-1 in WG. These data provide evidence that both the intensity and the duration of exercise affect the transcriptional regulation of metabolic genes in muscle in a fiber type-specific manner, possibly reflecting the relative stress imposed by the exercise bout. JF - American Journal of Physiology: Endocrinology and Metabolism AU - Hildebrandt, AL AU - Pilegaard, H AU - Neufer, P D AD - John B. Pierce Laboratory, 290 Congress Ave., New Haven, CT 06519, USA, dneufer@jbpierce.org Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - E1021 EP - E1027 VL - 285 IS - 5 SN - 0193-1849, 0193-1849 KW - Physical Education Index KW - Exercise physiology KW - Exercise (duration) KW - Exercise (intensity) KW - Enzymes KW - Proteins KW - Genetics (molecular) KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19197233?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology%3A+Endocrinology+and+Metabolism&rft.atitle=Differential+transcriptional+activation+of+select+metabolic+genes+in+response+to+variations+in+exercise+intensity+and+duration&rft.au=Hildebrandt%2C+AL%3BPilegaard%2C+H%3BNeufer%2C+P+D&rft.aulast=Hildebrandt&rft.aufirst=AL&rft.date=2003-11-01&rft.volume=285&rft.issue=5&rft.spage=E1021&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Physiology%3A+Endocrinology+and+Metabolism&rft.issn=01931849&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Exercise (intensity); Genetics (molecular); Exercise (duration); Proteins; Enzymes; Exercise physiology ER - TY - JOUR T1 - Mortality and predation in ecosystem models: is it important how these are expressed? AN - 19154921; 5744174 AB - The effects of the form of the grazing and mortality terms used in plankton models are well known. The same cannot be said for ecosystem models. As ecosystem models become more popular more needs to be known about the effects of model formulation on model behaviour and performance. The impact of the form of the grazing response function and mortality terms used in a biogeochemical ecosystem model are considered here. We show that in the large and inter-linked webs used in ecosystem models, model behaviour is far more sensitive to the form of the grazing term than to that of the mortality terms that close the modelled food web. When using biogeochemical ecosystem models in shallow marine ecosystems, the most dynamic and sophisticated functional responses describing grazing require more parameters and validation than the simpler Holling disk equation, but usually still lead to the same general conclusions about the system state and the effects of changes in forcing functions. Thus, the use of more complex functional responses is not necessarily warranted in many cases. Similarly, the extra effort and data required to explicitly represent the top predators (sharks, mammals and birds) is not necessary if they are not the focus of the study. A quadratic mortality term applied to intermediate predators (such as piscivores) is sufficient to achieve plausible model behaviour. It should be noted, however, that some degree of sophistication is required in the grazing and mortality terms. Use of simple linear functional responses and mortality terms is unsuitable for models used to consider a range of nutrient loading or harvesting scenarios. JF - Ecological Modelling AU - Fulton, E A AU - Smith, ADM AU - Johnson, C R AD - CSIRO Division of Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, beth.fulton@csiro.au Y1 - 2003/11// PY - 2003 DA - November 2003 SP - 157 EP - 178 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 169 IS - 1 SN - 0304-3800, 0304-3800 KW - ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Functional response KW - Mortality KW - Model closure KW - Biogeochemical KW - Ecosystem KW - Model KW - Marine KW - Ecosystems KW - Biogeochemical cycle KW - Grazing KW - Predation KW - Ecosystem models KW - Models KW - Predator prey interactions KW - Mortality causes KW - Food webs KW - Plankton KW - Q1 08482:Ecosystems and energetics KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19154921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Mortality+and+predation+in+ecosystem+models%3A+is+it+important+how+these+are+expressed%3F&rft.au=Fulton%2C+E+A%3BSmith%2C+ADM%3BJohnson%2C+C+R&rft.aulast=Fulton&rft.aufirst=E&rft.date=2003-11-01&rft.volume=169&rft.issue=1&rft.spage=157&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2FS0304-3800%2803%2900268-0 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Mortality; Ecosystems; Grazing; Biogeochemical cycle; Predator prey interactions; Predation; Plankton; Food webs; Mortality causes; Models; Ecosystem models; Marine DO - http://dx.doi.org/10.1016/S0304-3800(03)00268-0 ER - TY - JOUR T1 - The Natural Course of Bulimia Nervosa and Eating Disorder not Otherwise Specified is not Influenced by Personality Disorders AN - 18953153; 5747559 AB - Objective: To examine prospectively the natural course of bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) and to test the effects of personality disorder (PD) comorbidity on the outcomes. Method: Ninety-two female patients with current BN (N = 23) or EDNOS (N = 69) were evaluated at baseline enrollment in the Collaborative Longitudinal Personality Disorders Study (CLPS). Eating disorders (EDs) were assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders. Personality disorders (PDs) were assessed with the Diagnostic Interview for DSM-IV PD (DIPD-IV). The course of BN and EDNOS was assessed with the Longitudinal Interval Follow-up Evaluation and the course of PDs was evaluated with the Follow-Along version of the DIPD-IV at 6, 12, and 24 months. Results: Probability of remission at 24 months was 40% for BN and 59% for EDNOS. To test the effects of PD comorbidity on course, ED patients were divided into groups with no, one, and two or more PDs. Cox proportional regression analyses revealed that BN had a longer time to remission than EDNOS (p < .05). The number of PDs was not a significant predictor of time to remission, nor was the presence of Axis I psychiatric comorbidity or Global Assessment of Functioning scores. Analyses using proportional hazards regression with time-varying covariates revealed that PD instability was unrelated to changes in ED. Conclusions: BN has a worse 24-month course (longer time to remission) than EDNOS. The natural course of BN and EDNOS is not influenced significantly by the presence, severity, or time-varying changes of co-occurring PDs, co-occurring Axis I disorders, or by global functioning. JF - International Journal of Eating Disorders AU - Grilo, C M AU - Sanislow, CA AU - Shea, M T AU - Skodol, A E AU - Stout, R L AU - Pagano, ME AU - Yen, S AU - McGlashan, TH AD - Yale Psychiatric Research at Congress Place, Yale University School of Medicine, P.O. Box 208098, 301 Cedar Street (2nd Floor), New Haven, CT 06519, USA, carlos.grilo@yale.edu Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 319 EP - 330 VL - 34 IS - 3 SN - 0276-3478, 0276-3478 KW - Physical Education Index KW - Evaluation KW - Personality (traits) KW - Eating disorders KW - Bulimia KW - Interviews KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18953153?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Eating+Disorders&rft.atitle=The+Natural+Course+of+Bulimia+Nervosa+and+Eating+Disorder+not+Otherwise+Specified+is+not+Influenced+by+Personality+Disorders&rft.au=Grilo%2C+C+M%3BSanislow%2C+CA%3BShea%2C+M+T%3BSkodol%2C+A+E%3BStout%2C+R+L%3BPagano%2C+ME%3BYen%2C+S%3BMcGlashan%2C+TH&rft.aulast=Grilo&rft.aufirst=C&rft.date=2003-11-01&rft.volume=34&rft.issue=3&rft.spage=319&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Eating+Disorders&rft.issn=02763478&rft_id=info:doi/10.1002%2Feat.10196 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eating disorders; Bulimia; Personality (traits); Interviews; Evaluation DO - http://dx.doi.org/10.1002/eat.10196 ER - TY - JOUR T1 - Effect of population density on mortality after motor vehicle collisions AN - 18820949; 5708329 AB - The objective of this study was to evaluate the effect of population density on mortality after traffic crashes. Subjects were the drivers of vehicles requiring towing after collisions, sampled by NASS-GES during 1994-1998. Cases were classified by population of crash location (greater or lesser than 25, 000) and by population density of the driver's county of residence (using ZIP code and Census data). Cases were also categorized by age, belt use and vehicle speed. Analytic methods for weighted, stratified survey data were used to estimate effects on mortality. A total of 190, 721 cases with a specified crash location were identified in the sample, of which 93.7% had a specified population at the crash location, and 94.1% could be linked to the driver's county data. Mortality was higher in locations with populations less than 25, 000 and was inversely proportional to the driver's county population density. Age, belt use, and vehicle speed also affected mortality significantly, but the effect of rural location remained after controlling for these factors (O.R. 2.10, 95% C.I. 1.62-2.73). The excess risk for residents of rural areas to die in traffic crashes can be attributed in part to post-crash factors. JF - Accident Analysis & Prevention AU - Clark, DE AD - Department of Surgery, Maine Medical Center, 887 Congress Street, Suite 210, Portland, ME 04102, USA, clarkd@mmc.org Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 965 EP - 971 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 35 IS - 6 SN - 0001-4575, 0001-4575 KW - Health & Safety Science Abstracts; Risk Abstracts KW - R2 23020:Technological risks KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18820949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Accident+Analysis+%26+Prevention&rft.atitle=Effect+of+population+density+on+mortality+after+motor+vehicle+collisions&rft.au=Clark%2C+DE&rft.aulast=Clark&rft.aufirst=DE&rft.date=2003-11-01&rft.volume=35&rft.issue=6&rft.spage=965&rft.isbn=&rft.btitle=&rft.title=Accident+Analysis+%26+Prevention&rft.issn=00014575&rft_id=info:doi/10.1016%2FS0001-4575%2802%2900104-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0001-4575(02)00104-5 ER - TY - JOUR T1 - Soil carbon stocks and bulk density: spatial or cumulative mass coordinates as a basis of expression? AN - 17680043; 5773209 AB - Accounting for CO sub(2) fluxes by determining changes in stocks of soil carbon (C) as a result of land use change is an option for complying nations under the Kyoto Protocol. The 1996 IPCC guidelines for C accounting recommend that soil C stocks to a depth of 30 cm be used in such accounting. However, the soil bulk density often changes with land use and the soil C per unit ground area to a fixed depth will also change even without any change in the mass fraction of C in dry soil. This problem will generally arise when soil C accounting is taken to a fixed depth (i.e. uses 'spatial coordinates'). For accuracy in determining the land use change effects on soil C, soil sampling should be referred to a fixed dry soil mass per unit ground area (i.e. use 'cumulative mass coordinates'). There has been intermittent literature-discussion about this issue over several decades. Methods to accomplish C accounting on a mass coordinate basis, none of them accurate or efficient, have been suggested. Here, we propose a simple, accurate methodology for determining soil C stocks using cumulative mass coordinates, which does not involve repeat sampling trips, nominal specification of the location of boundaries between soil horizons, or independent sampling for determining soil bulk densities. Each core is taken a little (say 10 cm) below the nominal mass/depth required and the retrieved core is sliced into two at a point a little above the nominal mass/depth (say 10 cm above). An accurate determination of the depth of the core or slice is not needed, but an accurate determination of the dry mass of soil above and below the slice-point is required. Linear interpolation between these two measurements is then used to estimate the cumulative soil C per unit ground area to the target dry soil mass per unit ground area. Even though this method eliminates the need for reporting soil bulk densities for C accounting, it is urged that the bulk densities and density changes still be routinely reported. This is because such information is of fundamental importance for understanding and predicting the movement of fluids and substances carried in them within the soil and between the soil and the environment. Hence, these data are likely to be of fundamental importance in developing our future understanding and predictive capacity of soil C changes with land use change. JF - Global Change Biology AU - Gifford, R M AU - Roderick, M L AD - Cooperative Research Centre for Greenhouse Accounting, GPO Box 475, Canberra, ACT 2601, Australia, CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, Roger.Gifford@csiro.auor Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1507 EP - 1514 PB - Blackwell Science Ltd VL - 9 IS - 11 SN - 1354-1013, 1354-1013 KW - Ecology Abstracts KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17680043?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+Change+Biology&rft.atitle=Soil+carbon+stocks+and+bulk+density%3A+spatial+or+cumulative+mass+coordinates+as+a+basis+of+expression%3F&rft.au=Gifford%2C+R+M%3BRoderick%2C+M+L&rft.aulast=Gifford&rft.aufirst=R&rft.date=2003-11-01&rft.volume=9&rft.issue=11&rft.spage=1507&rft.isbn=&rft.btitle=&rft.title=Global+Change+Biology&rft.issn=13541013&rft_id=info:doi/10.1046%2Fj.1365-2486.2003.00677.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1046/j.1365-2486.2003.00677.x ER - TY - JOUR T1 - Functional Characterization of Polymorphisms in DNA Repair Genes Using Cytogenetic Challenge Assays AN - 14685055; 10652975 AB - Results are presented from an investigation in which the DNA repair function of certain variant genotypes was elucidated using cytogenetic challenge assays. Specifically, two groups of polymorphic DNA repair genes involved preferentially with base excision repair and nucleotide excision repair activities that correspond to the repair of X rays and UV light-induced DNA damage, respectively, were selected. Blood samples were collected from healthy adult males and females, and genomic DNA was extracted from isolated lymphocytes by a standard nonorganic procedure. The relationship between variant genotypes and the expression of X rays and UV light-induced chromosome aberrations was investigated. Significant genotype-specific repair defects to the inducing agents were observed, and heterozygous and homozygous variant genotypes were associated consistently with higher chromosome aberration than wild-type genes. The functions of the variant genotypes were complementary to each other in the same repair pathway, with limited overlap of genes from the other pathways. JF - Environmental Health Perspectives AU - Au, William W AU - Salama, Salama A AU - Sierra-Torres, Carlos H Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1843 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ULTRAVIOLET RADIATION KW - CYTOTOXICITY KW - DNA KW - X RAYS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14685055?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Functional+Characterization+of+Polymorphisms+in+DNA+Repair+Genes+Using+Cytogenetic+Challenge+Assays&rft.au=Au%2C+William+W%3BSalama%2C+Salama+A%3BSierra-Torres%2C+Carlos+H&rft.aulast=Au&rft.aufirst=William&rft.date=2003-11-01&rft.volume=111&rft.issue=15&rft.spage=1843&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ULTRAVIOLET RADIATION; CYTOTOXICITY; DNA; X RAYS; GENETICS, HUMAN ER - TY - JOUR T1 - Organization and Evolution of the Cyp2 Gene Cluster on Mouse Chromosome 7, and Comparison with the Syntenic Human Cluster AN - 14684164; 10652974 JF - Environmental Health Perspectives AU - Wang, Haoyi AU - Donley, Kyle M AU - Keeney, Diane S AU - Hoffman, Susan MG Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1835 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - SPECIES COMPARISONS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14684164?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Organization+and+Evolution+of+the+Cyp2+Gene+Cluster+on+Mouse+Chromosome+7%2C+and+Comparison+with+the+Syntenic+Human+Cluster&rft.au=Wang%2C+Haoyi%3BDonley%2C+Kyle+M%3BKeeney%2C+Diane+S%3BHoffman%2C+Susan+MG&rft.aulast=Wang&rft.aufirst=Haoyi&rft.date=2003-11-01&rft.volume=111&rft.issue=15&rft.spage=1835&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; SPECIES COMPARISONS; GENETICS, HUMAN ER - TY - JOUR T1 - Electrostatic Potential on Human Leukocyte Antigen: Implications for Putative Mechanism of Chronic Beryllium Disease AN - 14682206; 10652973 AB - Chronic beryllium disease (CBD) appears to affect a subset of exposed workers and to include an immunologic component. Onset of CBD is preceded by immunologic sensitization to Be. To investigate the basis for the suggested inter-individual genetic susceptibility, three-dimensional structural models of anti-human leukocyte antigen antibody proteins were constructed representing several distinct allotypes, and the electrostatic potential on the surface of the models was calculated. The allotypes were predicated on two types of alpha -chain sequences and five types of beta -chain sequences. Results revealed that the positions beta 55, beta 56, beta 69, beta 84, and beta 85 were implicated in susceptibility to CBD. JF - Environmental Health Perspectives AU - Snyder, James A AU - Weston, Ainsley AU - Tinkle, Sally S AU - Demchuk, Eugene Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1827 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - BERYLLIUM KW - DISEASES AND DISORDERS KW - SUSCEPTIBILITY KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14682206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Electrostatic+Potential+on+Human+Leukocyte+Antigen%3A+Implications+for+Putative+Mechanism+of+Chronic+Beryllium+Disease&rft.au=Snyder%2C+James+A%3BWeston%2C+Ainsley%3BTinkle%2C+Sally+S%3BDemchuk%2C+Eugene&rft.aulast=Snyder&rft.aufirst=James&rft.date=2003-11-01&rft.volume=111&rft.issue=15&rft.spage=1827&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; DISEASES AND DISORDERS; BERYLLIUM; SUSCEPTIBILITY; GENETICS, HUMAN ER - TY - JOUR T1 - ArrayTrack-Supporting Toxicogenomic Research at the U.S. Food and Drug Administration National Center for Toxicological Research AN - 14681402; 10652972 AB - ArrayTrack is presented, which is a toxicoinformatics integrated system being developed at FDA to meet the data management and analysis challenges associated with implementing toxicogenomic technologies. ArrayTrack contains three integrated components: a MicroarrayDB, which stores essential data associated with a microarray experiment; TOOL, which provides analysis capabilities for data visualization, normalization, significance analysis, clustering, and classification; and LIB, which contains information from public repositories. Each of the components is described in detail. JF - Environmental Health Perspectives AU - Tong, Weida AU - Cao, Xiaoxi AU - Harris, Stephen AU - Sun, Hongmei AU - Fang, Hong AU - Fuscoe, James AU - Harris, Angela Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1819 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - INFORMATION SYSTEMS, ENV KW - GENETICS, HUMAN KW - TOXICOLOGY KW - US FOOD AND DRUG ADMINISTRATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14681402?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=ArrayTrack-Supporting+Toxicogenomic+Research+at+the+U.S.+Food+and+Drug+Administration+National+Center+for+Toxicological+Research&rft.au=Tong%2C+Weida%3BCao%2C+Xiaoxi%3BHarris%2C+Stephen%3BSun%2C+Hongmei%3BFang%2C+Hong%3BFuscoe%2C+James%3BHarris%2C+Angela&rft.aulast=Tong&rft.aufirst=Weida&rft.date=2003-11-01&rft.volume=111&rft.issue=15&rft.spage=1819&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - INFORMATION SYSTEMS, ENV; TOXICOLOGY; GENETICS, HUMAN; US FOOD AND DRUG ADMINISTRATION ER - TY - JOUR T1 - Measurement of Pesticides and Other Toxicants in Amniotic Fluid as a Potential Biomarker of Prenatal Exposure: a Validation Study AN - 14680951; 10652762 AB - Amniotic fluid samples were collected from 100 women living in the San Joaquin Valley, CA, and analytical procedures for measuring nonspecific organophosphate pesticide metabolites, organophosphate-specific metabolites, pyrethroid pesticide metabolites, and pesticides with chlorinated phenol metabolites in urine were evaluated for transfer to amniotic fluid. The laboratory methods involved a solid-phase or liquid partitioning extraction with analysis using tandem mass spectrometry and isotope dilution gas chromatographymass spectrometry/mass spectrometry. The methods for measuring the metabolites in urine were found to be transferable to amniotic fluid with minor modifications. The presence of selected metabolites indicated that fetal exposures occurred as early as 1518 weeks gestation and may have reflected exposures to common ingredients in consumer products. JF - Environmental Health Perspectives AU - Bradman, Asa AU - Barr, Dana B AU - Henn, Birgit GClaus AU - Drumheller, Timothy AU - Curry, Cynthia AU - Eskenazi, Brenda Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1779 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PYRETHROID PESTICIDES KW - PREGNANCY KW - CHLOROPHENOLS KW - MEASUREMENTS AND SENSING KW - ORGANOPHOSPHATE PESTICIDES KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Measurement+of+Pesticides+and+Other+Toxicants+in+Amniotic+Fluid+as+a+Potential+Biomarker+of+Prenatal+Exposure%3A+a+Validation+Study&rft.au=Bradman%2C+Asa%3BBarr%2C+Dana+B%3BHenn%2C+Birgit+GClaus%3BDrumheller%2C+Timothy%3BCurry%2C+Cynthia%3BEskenazi%2C+Brenda&rft.aulast=Bradman&rft.aufirst=Asa&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1779&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; ORGANOPHOSPHATE PESTICIDES; PYRETHROID PESTICIDES; PREGNANCY; PESTICIDE EXPOSURE; CHLOROPHENOLS ER - TY - JOUR T1 - Neurobehavioral Performance and Work Experience in Florida Farmworkers AN - 14680890; 10652760 JF - Environmental Health Perspectives AU - Kamel, Freya AU - Rowland, Andrew S AU - Park, Lawrence P AU - Anger, WKent AU - Baird, Donna D AU - Gladen, Beth C AU - Moreno, Tirso Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1765 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - NEUROTOXICITY KW - AGRICULTURAL CHEMICALS KW - FLORIDA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Neurobehavioral+Performance+and+Work+Experience+in+Florida+Farmworkers&rft.au=Kamel%2C+Freya%3BRowland%2C+Andrew+S%3BPark%2C+Lawrence+P%3BAnger%2C+WKent%3BBaird%2C+Donna+D%3BGladen%2C+Beth+C%3BMoreno%2C+Tirso&rft.aulast=Kamel&rft.aufirst=Freya&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1765&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; NEUROTOXICITY; AGRICULTURAL CHEMICALS; FLORIDA ER - TY - JOUR T1 - Urinary Biomarkers of Exposure to Jet Fuel (JP-8) AN - 14680259; 10652759 AB - Spot urine samples were collected from 323 active-duty Air Force personnel on six US bases before and after a 4-h work shift, and levels of unmetabolized benzene and naphthalene and of 1- and 2-naphthol were measured as possible biomarkers of exposure to jet propulsion fuel-8 (JP-8). The levels were compared after a priori categorization of the subjects by exposure and by smoking status, and correlations of the urinary analytes with breath levels of benzene and naphthalene were explored. Results showed that smokers had significantly higher pre-exposure levels of all urinary analytes than nonsmokers, except for naphthalene. Postexposure, concentrations of all urinary analytes in the high-exposure group were three- to 28-fold higher than those in the low-exposure group and two- to 12-fold higher than those in the moderate-exposure group. Postexposure urinary measurements showed much larger correlation with measurements in breath and urine than did those for the corresponding pre-exposure samples. The overall results revealed that JP-8 was a significant source of exposure to benzene and naphthalene. JF - Environmental Health Perspectives AU - Serdar, Berrin AU - Egeghy, Peter P AU - Waidyanatha, Suramya AU - Gibson, Roger AU - Rappaport, Stephen M Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1760 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - BIOLOGICAL INDICATORS KW - NAPHTHALENE KW - JET ENGINE FUEL KW - CIGARETTE SMOKE KW - HEALTH SAFETY, OCCUPATIONAL KW - BENZENE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680259?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Urinary+Biomarkers+of+Exposure+to+Jet+Fuel+%28JP-8%29&rft.au=Serdar%2C+Berrin%3BEgeghy%2C+Peter+P%3BWaidyanatha%2C+Suramya%3BGibson%2C+Roger%3BRappaport%2C+Stephen+M&rft.aulast=Serdar&rft.aufirst=Berrin&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1760&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; AIR POLLUTION EFFECTS; BIOLOGICAL INDICATORS; NAPHTHALENE; CIGARETTE SMOKE; BENZENE; JET ENGINE FUEL ER - TY - JOUR T1 - Environmental, Occupational, and Genetic Risk Factors for alpha -1 Antitrypsin Deficiency AN - 14680228; 10652757 JF - Environmental Health Perspectives AU - Sharp, Richard R AU - de Serres, Frederick AU - Newman, Lee AU - Sandhaus, Robert A AU - Walsh, John W AU - Hood, Ernie AU - Harry, GJean Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1749 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - DEFICIENCY DISEASES KW - PATHOLOGY, HUMAN KW - PULMONARY DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680228?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Environmental%2C+Occupational%2C+and+Genetic+Risk+Factors+for+alpha+-1+Antitrypsin+Deficiency&rft.au=Sharp%2C+Richard+R%3Bde+Serres%2C+Frederick%3BNewman%2C+Lee%3BSandhaus%2C+Robert+A%3BWalsh%2C+John+W%3BHood%2C+Ernie%3BHarry%2C+GJean&rft.aulast=Sharp&rft.aufirst=Richard&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1749&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DEFICIENCY DISEASES; PATHOLOGY, HUMAN; PULMONARY DISORDERS ER - TY - JOUR T1 - Changing Heat-Related Mortality in the United States AN - 14680204; 10652751 AB - Daily mortality rates for 28 major US cities over the period 196498 were examined to explore whether annual heat-related mortality rates had changed over time. Death rates were examined on days in which the combination of high temperature and humidity was correlated with significantly elevated mortality rates. Analysis of the data showed that heat-related mortality declined consistently on a decadal basis. By the 1980s, mortality rates declined in 41% of the cities that had elevated mortality one decade earlier. Cities along the southern tier of the US exhibited the weakest heatmortality relationships. No relationship was found between temporal climate trends in apparent temperature and mortality responses. JF - Environmental Health Perspectives AU - Davis, Robert E AU - Knappenberger, Paul C AU - Michaels, Patrick J AU - Novicoff, Wendy M Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1712 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ATMOSPHERIC TEMPERATURE KW - MORTALITY PATTERNS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Changing+Heat-Related+Mortality+in+the+United+States&rft.au=Davis%2C+Robert+E%3BKnappenberger%2C+Paul+C%3BMichaels%2C+Patrick+J%3BNovicoff%2C+Wendy+M&rft.aulast=Davis&rft.aufirst=Robert&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1712&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ATMOSPHERIC TEMPERATURE; MORTALITY PATTERNS; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Radiographic Abnormalities and Exposure to Asbestos-Contaminated Vermiculite in the Community of Libby, Montana, USA AN - 14680054; 10652758 JF - Environmental Health Perspectives AU - Peipins, Lucy A AU - Lewin, Michael AU - Campolucci, Sharon AU - Lybarger, Jeffrey A AU - Miller, Aubrey AU - Middleton, Dan AU - Weis, Christopher Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1753 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MONTANA KW - HEALTH SAFETY, OCCUPATIONAL KW - MEDICAL SURVEILLANCE KW - ASBESTOS KW - PULMONARY DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680054?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Radiographic+Abnormalities+and+Exposure+to+Asbestos-Contaminated+Vermiculite+in+the+Community+of+Libby%2C+Montana%2C+USA&rft.au=Peipins%2C+Lucy+A%3BLewin%2C+Michael%3BCampolucci%2C+Sharon%3BLybarger%2C+Jeffrey+A%3BMiller%2C+Aubrey%3BMiddleton%2C+Dan%3BWeis%2C+Christopher&rft.aulast=Peipins&rft.aufirst=Lucy&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1753&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MONTANA; HEALTH SAFETY, OCCUPATIONAL; MEDICAL SURVEILLANCE; ASBESTOS; PULMONARY DISORDERS ER - TY - JOUR T1 - Serotonergic Systems Targeted by Developmental Exposure to Chlorpyrifos: Effects During Different Critical Periods AN - 14680020; 10652755 AB - The short-term effects of developmental chlorpyrifos exposure on serotonin (5HT) receptors, the high-affinity presynaptic 5HT transporter (5HTT) site, and the ability of 5HT to evoke stimulation or inhibition of adenylyl cyclase activity were studied. Using SpragueDawley rats, treatment regimens were chosen to span the threshold for systemic toxicity and/or inhibition of cholinesterase and to incorporate different critical periods of exposure in both pre- and postnatal periods. Results showed that the 5HT system represents a major target of chlorpyrifos in the developing brain, contributing to the noncholinergic components of neuroteratogenicity. The critical windows for effects on 5HT receptors, the presynaptic 5HTT site, and cell signaling mediated by 5HT extended over a wide developmental period ranging from the embryonic neural tube stage to terminal differentiation and synaptogenesis, and the effects were detectable at exposures below the threshold for symptoms of cholinergic hyperstimulation or systemic toxicity. JF - Environmental Health Perspectives AU - Aldridge, Justin E AU - Seidler, Frederic J AU - Meyer, Armando AU - Thillai, Indira AU - Slotkin, Theodore A Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1736 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - TERATOGENIC AGENTS KW - CHLORPYRIFOS KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14680020?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Serotonergic+Systems+Targeted+by+Developmental+Exposure+to+Chlorpyrifos%3A+Effects+During+Different+Critical+Periods&rft.au=Aldridge%2C+Justin+E%3BSeidler%2C+Frederic+J%3BMeyer%2C+Armando%3BThillai%2C+Indira%3BSlotkin%2C+Theodore+A&rft.aulast=Aldridge&rft.aufirst=Justin&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1736&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 12 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; TERATOGENIC AGENTS; CHLORPYRIFOS; AGE COMPARISONS ER - TY - JOUR T1 - Prenatal Exposures to Phthalates Among Women in New York City and Krakow, Poland AN - 14679977; 10652752 AB - Phthalate exposures in pregnant women were characterized using personal air and urine measurements. The subjects were women aged 1835 yr who were enrolled during pregnancy at prenatal clinics in New York City, USA, and in Krakow, Poland. Five congeners-diethyl phthalate, dibutyl phthalate, diethylhexyl phthalate, butyl benzyl phthalate, and di-isobutyl phthalate-were detected in all air samples analyzed, and in both cities, diethyl phthalate and dibutyl phthalate were the most prevalent phthalates. A significant correlation was found between personal air and urinary concentrations of butyl benzyl phthalate, dibutyl phthalate, and diethyl phthalate. JF - Environmental Health Perspectives AU - Adibi, Jennifer J AU - Perera, Frederica P AU - Jedrychowski, Wieslaw AU - Camann, David E AU - Barr, Dana AU - Jacek, Ryszard AU - Whyatt, Robin M Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1719 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR ANALYSIS KW - PREGNANCY KW - BIOACCUMULATION, HUMAN KW - PHTHALIC ACID ESTERS KW - NEW YORK CITY KW - POLAND KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14679977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prenatal+Exposures+to+Phthalates+Among+Women+in+New+York+City+and+Krakow%2C+Poland&rft.au=Adibi%2C+Jennifer+J%3BPerera%2C+Frederica+P%3BJedrychowski%2C+Wieslaw%3BCamann%2C+David+E%3BBarr%2C+Dana%3BJacek%2C+Ryszard%3BWhyatt%2C+Robin+M&rft.aulast=Adibi&rft.aufirst=Jennifer&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1719&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR ANALYSIS; PHTHALIC ACID ESTERS; PREGNANCY; NEW YORK CITY; BIOACCUMULATION, HUMAN; POLAND ER - TY - JOUR T1 - Association Between Gaseous Ambient Air Pollutants and Adverse Pregnancy Outcomes in Vancouver, Canada AN - 14679605; 10652761 AB - In Vancouver, BC, Canada, air pollution exposure data were combined with data on adverse pregnancy outcomes to examine possible associations. Exposure levels from conception through delivery were determined by linking with the environmental air pollution database, and for each live birth, average air pollution concentrations were calculated retrospectively for the first, second, and third month, the last and next to last month of pregnancy, and for the first, second, or third trimester. Low birth weight was associated with maternal exposure to sulfur dioxide during the first month of pregnancy, and preterm birth was associated with SO sub(2) and carbon monoxide exposure during the last month. Fetal growth retardation was associated consistently with maternal exposure to SO sub(2), nitrogen dioxide, and CO in the first month of pregnancy. JF - Environmental Health Perspectives AU - Liu, Shiliang AU - Krewski, Daniel AU - Shi, Yuanli AU - Chen, Yue AU - Burnett, Richard T Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1773 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SULFUR DIOXIDE KW - NITROGEN DIOXIDE KW - AIR POLLUTION EFFECTS KW - PREGNANCY KW - CARBON MONOXIDE KW - BRITISH COLUMBIA KW - URBAN ATMOSPHERE KW - AMBIENT AIR KW - REPRODUCTION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14679605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+Between+Gaseous+Ambient+Air+Pollutants+and+Adverse+Pregnancy+Outcomes+in+Vancouver%2C+Canada&rft.au=Liu%2C+Shiliang%3BKrewski%2C+Daniel%3BShi%2C+Yuanli%3BChen%2C+Yue%3BBurnett%2C+Richard+T&rft.aulast=Liu&rft.aufirst=Shiliang&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1773&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NITROGEN DIOXIDE; SULFUR DIOXIDE; AMBIENT AIR; AIR POLLUTION EFFECTS; REPRODUCTION, HUMAN; CARBON MONOXIDE; PREGNANCY; BRITISH COLUMBIA; URBAN ATMOSPHERE ER - TY - JOUR T1 - Is the Decline of the Increasing Incidence of Non-Hodgkin Lymphoma in Sweden and Other Countries a Result of Cancer Preventive Measures? AN - 14679576; 10652749 AB - Results are summarized from a number of studies that have looked at the association between human exposure to selected chemical compounds and the risk for non-Hodgkin lymphoma (NHL) in Sweden and other countries since the late 1970s. The hypothesis is that changes in exposure to the compounds could, at least partially, explain the observed changes in the incidence of NHL. The chemical compounds of interest include phenoxyacetic acids, chlorophenols, organic solvents, and persistent organic pollutants. The data suggest that limitation of exposure to these compounds may be reflected in cancer statistics over the following decades. JF - Environmental Health Perspectives AU - Hardell, Lennart AU - Eriksson, Mikael Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1704 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SOLVENTS KW - CANCER RISK KW - ORGANIC COMPOUNDS KW - CHEMICAL CONTAMINATION CONTROL KW - CHLOROPHENOLS KW - SWEDEN KW - DISEASES AND DISORDERS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14679576?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Is+the+Decline+of+the+Increasing+Incidence+of+Non-Hodgkin+Lymphoma+in+Sweden+and+Other+Countries+a+Result+of+Cancer+Preventive+Measures%3F&rft.au=Hardell%2C+Lennart%3BEriksson%2C+Mikael&rft.aulast=Hardell&rft.aufirst=Lennart&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1704&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; SOLVENTS; ORGANIC COMPOUNDS; SWEDEN; DISEASES AND DISORDERS; CHEMICAL CONTAMINATION CONTROL; CHLOROPHENOLS; TEMPORAL COMPARISONS ER - TY - JOUR T1 - From General Policy to Legal Rule: Aspirations and Limitations of the Precautionary Principle AN - 14677939; 10652766 AB - The precautionary principle seeks to formalize the application of precaution to regulatory decision-making, despite the lack of a standard definition of the principle. Over time, the precautionary principle has been transformed from a general aspiration policy into an obligatory legal requirement in a number of countries. However, the principle fails to provide a workable guide to the application of precaution in specific regulatory decisions. The inherent ambiguity of the precautionary principle is highlighted, which invites arbitrary application, both with respect to the risks to which it is applied and what it requires when it does apply. Specific examples of this ambiguity are cited, and the future of the principle is considered. JF - Environmental Health Perspectives AU - Marchant, Gary E Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1799 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - LAW KW - DECISION MAKING KW - ENV POLICY, GENERAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677939?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=From+General+Policy+to+Legal+Rule%3A+Aspirations+and+Limitations+of+the+Precautionary+Principle&rft.au=Marchant%2C+Gary+E&rft.aulast=Marchant&rft.aufirst=Gary&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1799&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 53 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; LAW; DECISION MAKING; ENV POLICY, GENERAL ER - TY - JOUR T1 - In Utero Exposure to Di-(2-ethylhexyl)phthalate and Duration of Human Pregnancy AN - 14677883; 10652763 AB - Concentrations of di-(2-ethylhexyl)phthalate (DEHP) and/or its main metabolite, mono-(2-ethylhexyl)phthalate (MEHP), were measured in cord blood samples collected from 84 consecutive newborns at Brindisi Hospital, Italy. In 74 of the samples, DEHP, MEHP, or both were detected, while DEHP and MEHP were each present in 65 samples. The mean DEHP and MEHP concentrations were 1.19 and 0.52 mu g/ml, respectively. A positive association was found between the absence of MEHP in cord blood and gestational age at delivery, but no other significant correlations were discerned. JF - Environmental Health Perspectives AU - Latini, Giuseppe AU - De Felice, Claudio AU - Presta, Giuseppe AU - Del Vecchio, Antonio AU - Paris, Irma AU - Ruggieri, Fabrizio AU - Mazzeo, Pietro Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1783 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - PHTHALIC ACID ESTERS KW - PREGNANCY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677883?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=In+Utero+Exposure+to+Di-%282-ethylhexyl%29phthalate+and+Duration+of+Human+Pregnancy&rft.au=Latini%2C+Giuseppe%3BDe+Felice%2C+Claudio%3BPresta%2C+Giuseppe%3BDel+Vecchio%2C+Antonio%3BParis%2C+Irma%3BRuggieri%2C+Fabrizio%3BMazzeo%2C+Pietro&rft.aulast=Latini&rft.aufirst=Giuseppe&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1783&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; PHTHALIC ACID ESTERS; REPRODUCTION, HUMAN; PREGNANCY ER - TY - JOUR T1 - Polybrominated Diphenyl Ethers (PBDEs) in U.S. Mothers' Milk AN - 14677859; 10652753 AB - Breast milk samples were collected from 47 women in Texas, and concentrations of polybrominated diphenyl ethers (PBDEs) were measured. The PBDE congener analyses were conducted by two experienced analytical laboratories, one in Hamburg, Germany, and another in Ottawa, ON, Canada. The analytical protocols used in the two laboratories are described. The concentrations of the sum of all PBDE congeners ranged 6.2419.0 ng/g lipid. The contribution of BDE-47 was greatest, followed by BDE-99, BDE-100, and BDE-153. The concentrations of PBDEs in the individual milk samples were markedly higher than those found in European samples. JF - Environmental Health Perspectives AU - Schecter, Arnold AU - Pavuk, Marian AU - Papke, Olaf AU - Ryan, John Jake AU - Birnbaum, Linda AU - Rosen, Robin Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1723 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ETHERS KW - TEXAS KW - BREAST MILK KW - FLAME RETARDANTS KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Polybrominated+Diphenyl+Ethers+%28PBDEs%29+in+U.S.+Mothers%27+Milk&rft.au=Schecter%2C+Arnold%3BPavuk%2C+Marian%3BPapke%2C+Olaf%3BRyan%2C+John+Jake%3BBirnbaum%2C+Linda%3BRosen%2C+Robin&rft.aulast=Schecter&rft.aufirst=Arnold&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1723&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ETHERS; TEXAS; BREAST MILK; BIOACCUMULATION, HUMAN; FLAME RETARDANTS ER - TY - JOUR T1 - Association Between Essential Tremor and Blood Lead Concentration AN - 14677811; 10652750 AB - Essential tremor (ET) is a neurologic disease characterized by tremor of the hands and/or head. In ET patients and control subjects, blood lead concentrations and lifetime occupational history were examined and compared. Results revealed that the blood Pb concentration was higher in ET patients than in controls, and the association between higher blood Pb concentration and the diagnosis of ET persisted after adjusting for confounding variables. In both groups, the prevalence of lifetime occupational exposure to Pb was similar, suggesting that the higher blood Pb concentration in ET patients was not due to increased risk of occupational exposure. JF - Environmental Health Perspectives AU - Louis, Elan D AU - Jurewicz, Eva C AU - Applegate, LaKeisha AU - Factor-Litvak, Pam AU - Parides, Michael AU - Andrews, Leslie AU - Slavkovich, Vesna Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1707 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - BLOOD LEAD LEVEL KW - NERVOUS DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677811?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+Between+Essential+Tremor+and+Blood+Lead+Concentration&rft.au=Louis%2C+Elan+D%3BJurewicz%2C+Eva+C%3BApplegate%2C+LaKeisha%3BFactor-Litvak%2C+Pam%3BParides%2C+Michael%3BAndrews%2C+Leslie%3BSlavkovich%2C+Vesna&rft.aulast=Louis&rft.aufirst=Elan&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1707&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; BLOOD LEAD LEVEL; NERVOUS DISORDERS ER - TY - JOUR T1 - Arsenic Exposure Accelerates Atherogenesis in Apolipoprotein E super(-)/ super(-) Mice AN - 14677550; 10652756 AB - Epidemiologic evidence has suggested a link between arsenic exposure and risk to vascular diseases related to atherosclerosis. In this study, apolipoprotein E super(-)/ super(-) mice and wild-type mice were exposed to sodium arsenite in drinking water for 24 weeks, and effects on the progression of atherosclerotic plaque formation were explored. In addition, human vascular cell culture systems were used to evaluate the effects of As on molecular events relevant to the major pathogenic mechanisms of atherosclerosis. Arsenic exposure through drinking water was found to increase atheroma formation in apolipoprotein E super(-)/ super(-) mice in parallel with increasing levels of As in the vessel wall. The introduction of an atherogenic diet for two weeks induced severe hypercholesterolemia without a significant effect on the lesion size. The wild-type mice were resistant to atherosclerosis, but atheroma formation could be triggered by a long-term high-fat diet. In vitro studies with the endothelial cell cultures suggested that As could cause direct endothelial dysfunction through oxidant formation. JF - Environmental Health Perspectives AU - Simeonova, Petia P AU - Hulderman, Tracy AU - Harki, Dan AU - Luster, Michael I Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1744 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ARSENIC KW - PATHOLOGY, ANIMALLABORATORY KW - CARDIOVASCULAR DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677550?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Arsenic+Exposure+Accelerates+Atherogenesis+in+Apolipoprotein+E+super%28-%29%2F+super%28-%29+Mice&rft.au=Simeonova%2C+Petia+P%3BHulderman%2C+Tracy%3BHarki%2C+Dan%3BLuster%2C+Michael+I&rft.aulast=Simeonova&rft.aufirst=Petia&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1744&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ARSENIC; PATHOLOGY, ANIMALLABORATORY; CARDIOVASCULAR DISORDERS ER - TY - JOUR T1 - Objectivity and Ethics in Environmental Health Science AN - 14677523; 10652768 AB - Using as a case example the research on cancer incidence after the 1979 nuclear accident at Three Mile Island, PA, the ways in which a contextual research practice can improve the rigor, ethics, and social responsibility of environmental health science are explored. The history of the accident at Three Mile Island is chronicled, along with the epidemiology of the accident, and results are presented from a re-analysis of the cancer incidence study, whichs was conducted in the context of conflict between residents who believed they had been injured and officials who denied that such injuries were possible. When the initial health studies were undertaken through official channels, citizens who believed they had been affected by accident emissions and their supporters were not included in the framing of questions, study design, analysis, interpretation, or communication of results, as the studies were funded by the nuclear industry and conducted under court-ordered constraints. Analysis of the case reveals that strong objectivity demands that scientists critically evaluate how the knowledge they create is shaped at every point by historical social forces, highlighting the need for scientists to be trained to engage in careful reflection about how the history of their discipline can affect their hypotheses and assumptions. JF - Environmental Health Perspectives AU - Wing, Steve Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1809 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - PUBLIC HEALTH KW - ENV ETHICS KW - ENV JUSTICE KW - RADIOLOGICAL CONTAMINATION KW - PENNSYLVANIA KW - RESEARCH, ENV KW - NUCLEAR ACCIDENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Objectivity+and+Ethics+in+Environmental+Health+Science&rft.au=Wing%2C+Steve&rft.aulast=Wing&rft.aufirst=Steve&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1809&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t maps N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; ENV ETHICS; CANCER RISK; RADIOLOGICAL CONTAMINATION; PENNSYLVANIA; PUBLIC HEALTH; RESEARCH, ENV; NUCLEAR ACCIDENTS ER - TY - JOUR T1 - The Sea Urchin Embryo as a Model for Mammalian Developmental Neurotoxicity: Ontogenesis of the High-Affinity Choline Transporter and Its Role in Cholinergic Trophic Activity AN - 14677498; 10652754 AB - Sea urchin Lytechinus variegatus embryos and larvae representing different stages of development were obtained from 12 females, and experiments were performed to examine the development of the high-affinity choline transporter over the period in which the organism uses acetylcholine as a trophic signal, along with the anomalies associated with inhibition of choline transport. Radioligand binding to the transporter was evaluated using hemicholinium-3. Results revealed that, even in the unfertilized egg, there was significant hemicholinium-3 binding associated with the cell membrane fraction. The amount of binding doubled by the stage and then rose more substantially at late blastula 2 stage and beyond. When dimethylaminoethanol, a membrane-permeable analog of hemicholinium-3, was added to the embryos at the two-cell stage at very high concentrations, cleavages were inhibited, while at lower concentrations, the two-cell stage subsequently developed malformations: overabundance of mesenchyme-like cells that accumulated first in the vegetal half of the blastocoel and later occupied all of the blastocoel, and absence of a second pair of arms in mid-pluteus. Pretreatment with acetylcholine or choline provided protection against the delayed-onset disruption of the later developmental events, indicating that the transporter plays the same critical role in the control of acetylcholine levels as it does in the mammalian brain. JF - Environmental Health Perspectives AU - Qiao, Dan AU - Nikitina, Lyudmila A AU - Buznikov, Gennady A AU - Lauder, Jean M AU - Seidler, Frederic J AU - Slotkin, Theodore A Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1730 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - SPECIES COMPARISONS KW - TERATOGENIC AGENTS KW - MARINE ORGANISMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677498?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Sea+Urchin+Embryo+as+a+Model+for+Mammalian+Developmental+Neurotoxicity%3A+Ontogenesis+of+the+High-Affinity+Choline+Transporter+and+Its+Role+in+Cholinergic+Trophic+Activity&rft.au=Qiao%2C+Dan%3BNikitina%2C+Lyudmila+A%3BBuznikov%2C+Gennady+A%3BLauder%2C+Jean+M%3BSeidler%2C+Frederic+J%3BSlotkin%2C+Theodore+A&rft.aulast=Qiao&rft.aufirst=Dan&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1730&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; SPECIES COMPARISONS; TERATOGENIC AGENTS; MARINE ORGANISMS ER - TY - JOUR T1 - Science and Social Responsibility in Public Health AN - 14677299; 10652767 AB - The social responsibilities of environmental health researchers are discussed, focusing on the responsibility of epidemiologists who are at the center of the science and practice of environmental health. Considered are where the responsibilities arise and how current approaches to environmental justice reflect those responsibilities, which, it is argued, include: the performance of scientific studies that matter to the health of the public, the performance of the very best science, the reporting of findings to the scientific community and responsibility for informing the study population and the communities within which the study population resides, the interpretation of study results, and recommendations for disease prevention and control interventions, as well as participation in carrying out the interventions through public-health policy-making and public-health advocacy. JF - Environmental Health Perspectives AU - Weed, Douglas L AU - McKeown, Robert E Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1804 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ENV ETHICS KW - ENV JUSTICE KW - PUBLIC HEALTH KW - RESEARCH, ENV KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Science+and+Social+Responsibility+in+Public+Health&rft.au=Weed%2C+Douglas+L%3BMcKeown%2C+Robert+E&rft.aulast=Weed&rft.aufirst=Douglas&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1804&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 44 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; ENV ETHICS; PUBLIC HEALTH; RESEARCH, ENV ER - TY - JOUR T1 - Qualitative Methods in Environmental Health Research AN - 14677271; 10652765 AB - In-depth qualitative studies of contaminated communities are performed to give voice to individuals and community-based organizations and to characterize the affected community in a complex fashion. Research in this area has focused typically on how lay people have discovered environmental problems and how they have acted on the knowledge. Here, the history and legacy of qualitative research in environmental health are explored, focusing on in-depth ethnographic studies of contaminated communities and citing the Woburn, MA, case in which dangerous levels of lead, arsenic, and chromium were discovered in the town's water supply. Woburn achieved national recognition as a toxic waste case that sparked many other communities to action. Several important components of qualitative research methods in environmental health research are identified and discussed, including flexibility in study design, the importance of empathy for the affected subjects and families, and member validation. JF - Environmental Health Perspectives AU - Brown, Phil Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1789 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - QUALITATIVE ANALYSIS KW - PUBLIC HEALTH KW - RESEARCH, ENV KW - PUBLIC PARTICIPATION KW - CHEMICAL CONTAMINATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Qualitative+Methods+in+Environmental+Health+Research&rft.au=Brown%2C+Phil&rft.aulast=Brown&rft.aufirst=Phil&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1789&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 40 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - QUALITATIVE ANALYSIS; PUBLIC HEALTH; RESEARCH, ENV; CHEMICAL CONTAMINATION; PUBLIC PARTICIPATION ER - TY - JOUR T1 - Oxidative Stress-Related Mechanisms Are Associated with Xenobiotics Exerting Excess Toxicity to Fanconi Anemia Cells AN - 14677248; 10652748 JF - Environmental Health Perspectives AU - Pagano, Giovanni AU - Manini, Paola AU - Bagchi, Debasis Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1699 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - REDOX KW - CYTOTOXICITY KW - DISEASES AND DISORDERS KW - OXIDANT STRESS KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14677248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Oxidative+Stress-Related+Mechanisms+Are+Associated+with+Xenobiotics+Exerting+Excess+Toxicity+to+Fanconi+Anemia+Cells&rft.au=Pagano%2C+Giovanni%3BManini%2C+Paola%3BBagchi%2C+Debasis&rft.aulast=Pagano&rft.aufirst=Giovanni&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1699&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - REDOX; CYTOTOXICITY; DISEASES AND DISORDERS; OXIDANT STRESS; LITERATURE SURVEYS ER - TY - JOUR T1 - Ethical Issues in Environmental Health Research AN - 14676758; 10652764 JF - Environmental Health Perspectives AU - Sharp, Richard R Y1 - 2003/11// PY - 2003 DA - Nov 2003 SP - 1786 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PUBLIC HEALTH KW - PUBLIC PARTICIPATION KW - ENV ETHICS KW - ENV JUSTICE KW - REGULATIONS, FEDERAL KW - RESEARCH, ENV KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14676758?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Ethical+Issues+in+Environmental+Health+Research&rft.au=Sharp%2C+Richard+R&rft.aulast=Sharp&rft.aufirst=Richard&rft.date=2003-11-01&rft.volume=111&rft.issue=14&rft.spage=1786&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 39 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; ENV ETHICS; PUBLIC HEALTH; REGULATIONS, FEDERAL; RESEARCH, ENV; PUBLIC PARTICIPATION ER - TY - JOUR T1 - Initial and Long-Term Efficacy of a Lipid Emulsion of Amphotericin B Desoxycholate in the Management of Canine Leishmaniasis AN - 1285082809; 11805679 AB - Sixteen dogs in which canine leishmaniasis (CL) was diagnosed by positive identification of Leishmania amastigotes in bone marrow samples were treated with a mixture of amphotericin B (AmB) desoxycholate in soybean oil. To prevent the toxicity of AmB, dogs were pretreated with saline (50 mL/kg) and mannitol (2 g/kg). Dogs were treated twice weekly with an increasing dosage of amphotericin (0.8--2.5 mg/kg) for between 8 and 10 sessions. Transient adverse effects (anorexia, vomiting, or both) appeared in 81% of the dogs during therapy. At the end of the course, all dogs were clinically cured, with no parasites observed in bone marrow smears. Six of the 16 dogs (38%) were positive by polymerase chain reaction (PCR) in bone marrow samples at some stage of their follow-up, but only 2 were positive at the first test after treatment, which was performed within 5 months after the end of the therapy. The other 4 dogs were initially negative and became PCR-positive at subsequent examinations. Three of these 6 dogs also experienced a clinical relapse. Four dogs had at least 3 consecutive negative PCR tests during a minimum period of 18 months and were clinically cured. The results of the present study indicate that despite having a high initial effectiveness in the treatment of CL, relapses can occur with the described protocol. Also, a single negative PCR result in a recently treated dog cannot be interpreted as a complete cure. Revised March 17 and June 17, 2003; Accepted July 17, 2003. JF - Journal of Veterinary Internal Medicine AU - Cortadellas, Oscar AD - From Clinica Veterinaria Germanias, Gandia-Valencia, Spain. Previously presented partially as a free communication at the 27th WSA-VA Congress, Granada, 2002., cl-veterinaria-germanias@telefonica.net Y1 - 2003/11// PY - 2003 DA - November 2003 SP - 808 EP - 812 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 17 IS - 6 SN - 0891-6640, 0891-6640 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Leishmaniasis KW - Amphotericin B KW - Parasites KW - Amastigotes KW - Vomiting KW - Nucleotide sequence KW - Lipids KW - Bone marrow KW - Therapy KW - Toxicity KW - Emulsions KW - Soybeans KW - Oil KW - Leishmania KW - Mannitol KW - anorexia KW - DNA KW - Polymerase chain reaction KW - Side effects KW - K 03410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285082809?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Veterinary+Internal+Medicine&rft.atitle=Initial+and+Long-Term+Efficacy+of+a+Lipid+Emulsion+of+Amphotericin+B+Desoxycholate+in+the+Management+of+Canine+Leishmaniasis&rft.au=Cortadellas%2C+Oscar&rft.aulast=Cortadellas&rft.aufirst=Oscar&rft.date=2003-11-01&rft.volume=17&rft.issue=6&rft.spage=808&rft.isbn=&rft.btitle=&rft.title=Journal+of+Veterinary+Internal+Medicine&rft.issn=08916640&rft_id=info:doi/10.1111%2Fj.1939-1676.2003.tb02518.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Parasites; Lipids; Nucleotide sequence; Therapy; DNA; Polymerase chain reaction; Toxicity; Emulsions; Leishmaniasis; Amphotericin B; Vomiting; Amastigotes; Bone marrow; Soybeans; Oil; anorexia; Mannitol; Side effects; Leishmania DO - http://dx.doi.org/10.1111/j.1939-1676.2003.tb02518.x ER - TY - CPAPER T1 - Use of sparse genomic tiling arrays for mutation detection AN - 39716168; 3796234 AU - Weismann, S Y1 - 2003/10/21/ PY - 2003 DA - 2003 Oct 21 KW - CPI, Conference Papers Index KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39716168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Use+of+sparse+genomic+tiling+arrays+for+mutation+detection&rft.au=Weismann%2C+S&rft.aulast=Weismann&rft.aufirst=S&rft.date=2003-10-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: HUGO Secretariat, 142-144 Harley Street, London W1N 1AH, UK; phone: 44 (0207) 935 8085; fax: 44 (0207) 935 8341; email: hugo@hugo-international.org. Poster Paper No. 32 N1 - Last updated - 2010-05-03 ER - TY - GEN T1 - Missile Proliferation and the Strategic Balance in South Asia [Includes Map and Tables] AN - 1679115134; WM00596 AB - Summarizes intelligence on Indian and Pakistani missile programs, and reviews the diplomatic history of South Asia, examining the implications of U.S. policy decisions for regional security. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2003 SP - 38 KW - Ballistic missiles KW - Command and control KW - India-United States relations KW - Indian nuclear program KW - Korea (North) KW - Missile flight tests KW - Nuclear nonproliferation KW - Nuclear weapons test bans KW - Pakistan-United States relations KW - Pakistani nuclear program KW - Terrorism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679115134?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_wm&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Missile+Proliferation+and+the+Strategic+Balance+in+South+Asia+%5BIncludes+Map+and+Tables%5D&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2003-10-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - Missile Technology Control Regime N1 - Analyte descriptor - NSA document type: Report N1 - Last updated - 2015-06-16 ER - TY - GEN T1 - Do Workers with Low Lifetime Earnings Really Have Low Earnings Every Year? Implications for Social Security Reform AN - 61690649; 200826613 AB - When it comes to retirement income policy, there is a general perception that workers have full 40-year working careers before retiring. Further, it is generally assumed that workers with low lifetime earnings have low earnings in each year during a normal working career. The basic research question is why do some workers have low lifetime earnings? Is it due to low earnings in every year, or is it due to some years of no earnings combined with years of relatively modest earnings? The key findings from this paper are: (1) most individuals with minimum (and subminimum) wage lifetime average earnings are women, and (2) most of these women have low lifetime average earnings because of fewer years with earnings, rather than low earnings in each year of a 40-year working career. JF - SSRN Working Paper Series AU - Hungerford, Thomas AD - U.S. Congressional Research Service Y1 - 2003/10/13/ PY - 2003 DA - 2003 Oct 13 PB - Social Science Research Network (SSRN), Rochester NY KW - Earnings Patterns KW - Social Security KW - Low-wage Workers KW - Low Income Groups KW - Wages KW - Reform KW - 0621: complex organization; jobs, work organization, workplaces, & unions KW - Low Income Groups KW - Wages KW - Reform KW - Social Security KW - 0621: complex organization; jobs, work organization, workplaces, & unions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61690649?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=preprint&rft.jtitle=SSRN+Working+Paper+Series&rft.atitle=Do+Workers+with+Low+Lifetime+Earnings+Really+Have+Low+Earnings+Every+Year%3F+Implications+for+Social+Security+Reform&rft.au=Hungerford%2C+Thomas&rft.aulast=Hungerford&rft.aufirst=Thomas&rft.date=2003-10-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=SSRN+Working+Paper+Series&rft.issn=&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2008-10-01 N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Cystine uptake prevents production of hydrogen peroxide by Lactobacillus fermentum BR11 AN - 18893194; 5770743 AB - BspA is an abundant surface protein from Lactobacillus fermentum BR11, and is required for normal cystine uptake. In previous studies, a mutant strain deficient in BspA (L. fermentum PNG201) was found to be sensitive to oxidative stress. In this study, the biochemical basis for this was explored. It was found that under aerobic batch culture conditions in de Mann-Rogosa-Sharpe medium, both L. fermentum BR11 and PNG201 entered stationary phase due to hydrogen peroxide accumulation. However, this took place at a lower optical density for PNG201 than for BR11. Measurements of hydrogen peroxide levels revealed that the BspA mutant strain overproduces this compound. Addition of 6 mM cystine to aerobic cultures was found to prevent hydrogen peroxide production by both the BR11 and PNG201 strains, but lower cystine concentrations depressed hydrogen peroxide production in BR11 more efficiently than in PNG201. Each mole of cystine was able to prevent the production of several moles of hydrogen peroxide by L. fermentum BR11, suggesting that hydrogen peroxide breakdown is dependent upon a thiol that cycles between reduced and oxidized states. It was concluded that peroxide breakdown by L. fermentum BR11 is dependent upon exogenous cystine. It is most probable that the imported L-cystine is catabolized by a cystathionine lyase and then converted into a thiol reductant for a peroxidase. JF - FEMS Microbiology Letters AU - Hung, J AU - Cooper, D AU - Turner AU - Walsh, T AU - Giffard, P M AD - Infectious Disease Program, Faculty of Science, Queensland University of Technology, G.P.O. Box 2434, Brisbane, Qld 4001, Australia, p.giffard@qut.edu.au Y1 - 2003/10/10/ PY - 2003 DA - 2003 Oct 10 SP - 93 EP - 99 PB - Federation of European Microbiological Societies VL - 227 IS - 1 SN - 0378-1097, 0378-1097 KW - BspA protein KW - cysteine KW - cystine KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology KW - Lactobacillus fermentum KW - Hydrogen peroxide KW - Oxidative stress KW - Mutants KW - G 07320:Bacterial genetics KW - J 02722:Biodegradation, growth, nutrition and leaching UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18893194?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Microbiology+Letters&rft.atitle=Cystine+uptake+prevents+production+of+hydrogen+peroxide+by+Lactobacillus+fermentum+BR11&rft.au=Hung%2C+J%3BCooper%2C+D%3BTurner%3BWalsh%2C+T%3BGiffard%2C+P+M&rft.aulast=Hung&rft.aufirst=J&rft.date=2003-10-10&rft.volume=227&rft.issue=1&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Letters&rft.issn=03781097&rft_id=info:doi/10.1016%2FS0378-1097%2803%2900653-0 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Oxidative stress; Hydrogen peroxide; Mutants; Lactobacillus fermentum DO - http://dx.doi.org/10.1016/S0378-1097(03)00653-0 ER - TY - JOUR T1 - Trans unsaturated fatty acids are less oxidizable than cis unsaturated fatty acids and protect endogenous lipids from oxidation in lipoproteins and lipid bilayers. AN - 75733557; 14516205 AB - Epidemiological data suggest that dietary trans unsaturated fatty acids increase the risk of heart disease; however, the underlying mechanisms are unclear. In this study, we investigated one possible mechanism, namely, their effect on LDL oxidation. Supplementation of LDL with 10% 16:1 trans-cholesteryl ester (CE) inhibited the oxidation compared to that with 16:1 cis-CE. Total replacement of core lipids with 18:2 trans,trans-CE decreased the rate of LDL oxidation by 19% compared to replacement with 18:2 cis,cis-CE. When the surface phosphoglycerides were replaced with either 16:0-18:2 cis,cis-phosphatidylcholine (PC) or 16:0-18:2 trans,trans-PC, the latter was found to inhibit the rate and increase the lag time of oxidation to a greater extent than the former. To confirm these findings, we studied the oxidation of PC liposomes by assessing the formation of conjugated dienes or the degradation of a fluorescently labeled PC. By both methods, the 16:0-18:2 trans,trans-PC exhibited greater resistance to oxidation than the 16:0-18:2 cis,cis-PC. Eliminating the fluidity differences did not completely eliminate the differences in oxidation rates, suggesting that the trans double bond is inherently resistant to oxidation. The composition of the conjugated hydroperoxy products formed after oxidation differed markedly for the two 18:2 isomers. Supplementation of 16:0-18:2 cis,cis-PC liposomes with 20 mol % di16:1 trans-PC retarded oxidation rates to a greater extent than supplementation with di16:1 cis-PC. These studies show that dietary trans unsaturated fatty acids decrease the rate of lipid peroxidation, an effect that may mitigate the atherogenic effect of these fatty acids. JF - Biochemistry AU - Sargis, Robert M AU - Subbaiah, Papasani V AD - Department of Biochemistry, Rush Medical College, 1653 West Congress Parkway, Chicago, Illinois 60612, USA. Y1 - 2003/10/07/ PY - 2003 DA - 2003 Oct 07 SP - 11533 EP - 11543 VL - 42 IS - 39 SN - 0006-2960, 0006-2960 KW - Alkadienes KW - 0 KW - Amidines KW - Cholesterol Esters KW - Esters KW - Fatty Acids, Unsaturated KW - Glycerophospholipids KW - Lipid Bilayers KW - Lipid Peroxides KW - Lipids KW - Lipoproteins, LDL KW - Liposomes KW - Membranes, Artificial KW - Phosphatidylcholines KW - 2,2'-azobis(2-amidinopropane) KW - 7381JDR72F KW - Copper Sulfate KW - LRX7AJ16DT KW - Index Medicus KW - Amidines -- chemistry KW - Esters -- chemistry KW - Alkadienes -- chemistry KW - Temperature KW - Alkadienes -- analysis KW - Oxidation-Reduction KW - Esters -- analysis KW - Glycerophospholipids -- chemistry KW - Spectrometry, Fluorescence -- methods KW - Phosphatidylcholines -- chemistry KW - Cholesterol Esters -- chemistry KW - Isomerism KW - Liposomes -- chemistry KW - Cholesterol Esters -- pharmacology KW - Copper Sulfate -- chemistry KW - Lipid Metabolism KW - Lipid Peroxides -- analysis KW - Lipoproteins, LDL -- chemistry KW - Fatty Acids, Unsaturated -- chemistry KW - Lipids -- chemistry KW - Lipoproteins, LDL -- metabolism KW - Lipid Bilayers -- chemistry KW - Fatty Acids, Unsaturated -- pharmacology KW - Lipid Bilayers -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/75733557?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biochemistry&rft.atitle=Trans+unsaturated+fatty+acids+are+less+oxidizable+than+cis+unsaturated+fatty+acids+and+protect+endogenous+lipids+from+oxidation+in+lipoproteins+and+lipid+bilayers.&rft.au=Sargis%2C+Robert+M%3BSubbaiah%2C+Papasani+V&rft.aulast=Sargis&rft.aufirst=Robert&rft.date=2003-10-07&rft.volume=42&rft.issue=39&rft.spage=11533&rft.isbn=&rft.btitle=&rft.title=Biochemistry&rft.issn=00062960&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-10-29 N1 - Date created - 2003-09-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A past psychiatric history may be a risk factor for topiramate-related psychiatric and cognitive adverse events. AN - 75743880; 14527497 AB - Topiramate (TPM) is a new antiepileptic drug (AED) that has been found to be associated with a high prevalence of cognitive adverse events (CAEs). The prevalence of psychiatric adverse events (PAEs) has yet to be established. The purpose of this study was to determine the prevalence of PAEs related to TPM when used in polytherapy regimens in a large cohort of adult patients with epilepsy, to identify any association between the occurrences of CAEs and PAEs and to identify predictors of PAEs and CAEs. Investigators from 16 epilepsy centers (PADS group) prospectively obtained postmarketing safety and efficacy data on 596 patients aged 16 years and older. All data were recorded on standardized data retrieval forms, completed at the initial visit, while follow-up data were obtained every 6 months or at the time of discontinuation. PAEs were identified in 75 (12.6%) patients: 30 (5%) experienced symptoms of depression and 34 (5.7%) of aggressive behavior and irritability, while 9 patients experienced symptoms of psychosis (1.5%). CAEs were reported by 247 (41.5%) patients. There was a significant association between the occurrences of CAEs and PAEs. A past psychiatric history was a predictor of CAEs, while older age and past psychiatric history were predictors of PAEs. The use of TPM in polytherapy regimens can cause PAEs and CAEs and their occurrence is significantly correlated. Patients with a past psychiatric history may be at a higher risk for experiencing PAEs and CAEs. JF - Epilepsy & behavior : E&B AU - Kanner, Andres M AU - Wuu, Joanne AU - Faught, Edward AU - Tatum, William O AU - Fix, Aaron AU - French, Jacqueline A AU - PADS Investigators AD - Department of Neurological Sciences, Rush-Presbyterian St. Luke's Medical Center, Rush Medical College, 1653 West Congress Parkway, Chicago, IL 60612, USA. akanner@rush.edu ; PADS Investigators Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 548 EP - 552 VL - 4 IS - 5 SN - 1525-5050, 1525-5050 KW - Anticonvulsants KW - 0 KW - topiramate KW - 0H73WJJ391 KW - Fructose KW - 30237-26-4 KW - Index Medicus KW - Prospective Studies KW - Aged, 80 and over KW - Risk Factors KW - Humans KW - Adult KW - Aged KW - Middle Aged KW - Adolescent KW - Male KW - Female KW - Fructose -- analogs & derivatives KW - Fructose -- adverse effects KW - Epilepsy -- psychology KW - Epilepsy -- complications KW - Anticonvulsants -- adverse effects KW - Mental Disorders -- psychology KW - Cognition Disorders -- chemically induced KW - Epilepsy -- drug therapy KW - Mental Disorders -- complications KW - Cognition Disorders -- psychology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/75743880?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epilepsy+%26+behavior+%3A+E%26B&rft.atitle=A+past+psychiatric+history+may+be+a+risk+factor+for+topiramate-related+psychiatric+and+cognitive+adverse+events.&rft.au=Kanner%2C+Andres+M%3BWuu%2C+Joanne%3BFaught%2C+Edward%3BTatum%2C+William+O%3BFix%2C+Aaron%3BFrench%2C+Jacqueline+A%3BPADS+Investigators&rft.aulast=Kanner&rft.aufirst=Andres&rft.date=2003-10-01&rft.volume=4&rft.issue=5&rft.spage=548&rft.isbn=&rft.btitle=&rft.title=Epilepsy+%26+behavior+%3A+E%26B&rft.issn=15255050&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-12-05 N1 - Date created - 2003-10-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Raman spectroscopy of some complex arsenate minerals-implications for soil remediation. AN - 75707469; 14499841 AB - The application of spectroscopy to the study of contaminants in soils is important. Among the many contaminants is arsenic, which is highly labile and may leach to non-contaminated areas. Minerals of arsenate may form depending upon the availability of specific cations for example calcium and iron. Such minerals include carminite, pharmacosiderite and talmessite. Each of these arsenate minerals can be identified by its characteristic Raman spectrum enabling identification. JF - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy AU - Frost, Ray L AU - Kloprogge, J Theo AD - Centre for Instrumental and Developmental Chemistry, Queensland University of Technology, 2 George Street, GPO Box 2434, Brisbane, Qld 4001, Australia. r.frost@qut.edu.au Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 2797 EP - 2804 VL - 59 IS - 12 SN - 1386-1425, 1386-1425 KW - Arsenates KW - 0 KW - Minerals KW - Soil KW - Soil Pollutants KW - Index Medicus KW - Spectrum Analysis, Raman KW - Arsenates -- chemistry KW - Minerals -- chemistry KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/75707469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.atitle=Raman+spectroscopy+of+some+complex+arsenate+minerals-implications+for+soil+remediation.&rft.au=Frost%2C+Ray+L%3BKloprogge%2C+J+Theo&rft.aulast=Frost&rft.aufirst=Ray&rft.date=2003-10-01&rft.volume=59&rft.issue=12&rft.spage=2797&rft.isbn=&rft.btitle=&rft.title=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.issn=13861425&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-03 N1 - Date created - 2003-09-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Raman spectroscopy of selected lead minerals of environmental significance. AN - 75701360; 14499830 AB - The Raman spectra of the minerals cerrusite (PbCO(3)), hydrocerrusite (Pb(2)(OH)(2)CO(3)), phosgenite (Pb(2)CO(3)Cl(2)) and laurionite (Pb(OH)Cl) have been used to qualitatively determine their presence. Laurionite and hydrocerrusite have characteristic hydroxyl stretching bands at 3506 and 3576 cm(-1). Laurionite is also characterised by broad low intensity bands centred at 730 and 595 cm(-1) attributed to hydroxyl deformation vibrations. The minerals cerrusite, hydrocerrusite and phosgenite have characteristic CO (nu(1)) symmetric stretching bands observed at 1061, 1054 and 1053 cm(-1). Phosgenite displays complexity in the CO (nu(3)) antisymmetric stretching region with bands observed at 1384, 1327 and 1304 cm(-1). Cerrusite shows bands at 1477, 1424, 1376 and 1360 cm(-1). The hydrocerrusite Raman spectrum has bands at slightly different positions from cerrusite, with bands at 1479, 1420, 1378 and 1365 cm(-1). The complexity of the nu(3) region is also reflected in the nu(2) and nu(4) regions with the observation of multiple bands. Laurionite is characterised by two intense bands at 328 and 272 cm(-1) attributed to PbO and PbCl stretching bands. Importantly, all four minerals are characterized by their Raman spectra, enabling the mineral identification in leachates and contaminants of environmental significance. JF - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy AU - Frost, Ray L AU - Martens, Wayde AU - Kloprogge, J Theo AU - Ding, Zhe AD - School of Physical and Chemical Sciences, Queensland University of Technology, G.P.O. Box 2434, Brisbane, Qld 4001, Australia. r.frost@qut.edu.au Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 2705 EP - 2711 VL - 59 IS - 12 SN - 1386-1425, 1386-1425 KW - Environmental Pollutants KW - 0 KW - Minerals KW - Lead KW - 2P299V784P KW - Index Medicus KW - Minerals -- chemistry KW - Lead -- chemistry KW - Spectrum Analysis, Raman UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/75701360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.atitle=Raman+spectroscopy+of+selected+lead+minerals+of+environmental+significance.&rft.au=Frost%2C+Ray+L%3BMartens%2C+Wayde%3BKloprogge%2C+J+Theo%3BDing%2C+Zhe&rft.aulast=Frost&rft.aufirst=Ray&rft.date=2003-10-01&rft.volume=59&rft.issue=12&rft.spage=2705&rft.isbn=&rft.btitle=&rft.title=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.issn=13861425&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-03 N1 - Date created - 2003-09-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Acupuncture for substance abuse. AN - 73660796; 13678552 AB - Acupuncture, in the form of insertion of needles bilaterally in the outer ears, is widely used for the treatment of addiction in the US. However, support for this form of treatment from controlled studies has not been consistent. This article examines recent clinical trials of acupuncture for addiction treatment, with a goal of conveying to the reader some of the complex issues involved in conducting studies in this area. Acupuncture trials in addictions frequently have been conducted without preliminary dose-ranging studies to establish efficacious doses of the experimental treatment, use needle insertion controls of unknown degrees of activity, and present no rationale for the type or intensity of concurrently offered psychotherapy. At the present time, it is premature to put forth recommendations for or against acupuncture for the treatment of addiction based on evidence from extant studies. JF - Current psychiatry reports AU - Margolin, Arthur AD - Department of Psychiatry, Yale University School of Medicine, Welch Building, 495 Congress Avenue, New Haven, CT 06519, USA. arthur.margolin@yale.edu Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 333 EP - 339 VL - 5 IS - 5 SN - 1523-3812, 1523-3812 KW - Index Medicus KW - Humans KW - Treatment Outcome KW - Clinical Trials as Topic KW - Substance-Related Disorders -- therapy KW - Acupuncture, Ear -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73660796?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+psychiatry+reports&rft.atitle=Acupuncture+for+substance+abuse.&rft.au=Margolin%2C+Arthur&rft.aulast=Margolin&rft.aufirst=Arthur&rft.date=2003-10-01&rft.volume=5&rft.issue=5&rft.spage=333&rft.isbn=&rft.btitle=&rft.title=Current+psychiatry+reports&rft.issn=15233812&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-01-06 N1 - Date created - 2003-09-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Cytochrome c oxidase inhibition in the rice weevil Sitophilus oryzae (L.) by formate, the toxic metabolite of volatile alkyl formates. AN - 71271318; 14559295 AB - Volatile alkyl formates are potential replacements for the ozone-depleting fumigant, methyl bromide, as postharvest insecticides and here we have investigated their mode of insecticidal action. Firstly, a range of alkyl esters, ethanol and formic acid were tested in mortality bioassays with adults of the rice weevil, Sitophilus oryzae (L.) and the grain borer, Rhyzopertha dominica (F.) to determine whether the intact ester or one of its components was the toxic moiety. Volatile alkyl formates and formic acid caused similar levels of mortality (LC(50) 131-165 micromol l(-1)) to S. oryzae and were more potent than non-formate containing alkyl esters and ethanol (LC(50)>275 micromol l(-1)). The order of potency was the same in R. dominica. Ethyl formate was rapidly metabolised in vitro to formic acid when incubated with insect homogenates, presumably through the action of esterases. S. oryzae and R. dominica fumigated with a lethal dose of ethyl formate had eight and 17-fold higher concentrations of formic acid, respectively, in their bodies than untreated controls. When tested against isolated mitochondria from S. oryzae, alkyl esters, alcohols, acetate and propionate salts were not inhibitory towards cytochrome c oxidase (EC 1.9.3.1), but sodium cyanide and sodium formate were inhibitory with IC(50) values of 0.0015 mM and 59 mM, respectively. Volatile formate esters were more toxic than other alkyl esters, and this was found to be due, at least in part, to their hydrolysis to formic acid and its inhibition of cytochrome c oxidase. JF - Comparative biochemistry and physiology. Toxicology & pharmacology : CBP AU - Haritos, V S AU - Dojchinov, G AD - CSIRO Entomology, G.P.O. Box 1700, Canberra ACT 2601, Australia. victoria.haritos@csiro.au Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 135 EP - 143 VL - 136 IS - 2 SN - 1532-0456, 1532-0456 KW - Enzyme Inhibitors KW - 0 KW - Insecticides KW - Propionates KW - Electron Transport Complex IV KW - EC 1.9.3.1 KW - propionic acid KW - JHU490RVYR KW - Index Medicus KW - Animals KW - Dose-Response Relationship, Drug KW - Mitochondria -- enzymology KW - Mitochondria -- drug effects KW - Lethal Dose 50 KW - Biological Assay KW - Volatilization KW - Fumigation KW - Propionates -- toxicity KW - Beetles -- enzymology KW - Enzyme Inhibitors -- toxicity KW - Electron Transport Complex IV -- antagonists & inhibitors KW - Propionates -- metabolism KW - Electron Transport Complex IV -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71271318?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Comparative+biochemistry+and+physiology.+Toxicology+%26+pharmacology+%3A+CBP&rft.atitle=Cytochrome+c+oxidase+inhibition+in+the+rice+weevil+Sitophilus+oryzae+%28L.%29+by+formate%2C+the+toxic+metabolite+of+volatile+alkyl+formates.&rft.au=Haritos%2C+V+S%3BDojchinov%2C+G&rft.aulast=Haritos&rft.aufirst=V&rft.date=2003-10-01&rft.volume=136&rft.issue=2&rft.spage=135&rft.isbn=&rft.btitle=&rft.title=Comparative+biochemistry+and+physiology.+Toxicology+%26+pharmacology+%3A+CBP&rft.issn=15320456&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-28 N1 - Date created - 2003-10-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Representivity: False Sisterhood or Universal Women's Interests? The South African Experience AN - 60698959; 200414308 AB - Explores the contribution of the African National Congress (ANC) women MPs to the improvement of gender equality both in Parliament & in the South African society & argues that women's or gender groups in Parliament cannot politically represent a universal women's interest. The author writes as an activist of the ANC, the South African Communist Party (SACP), & a member of the South African Parliament for two years after the first democratic elections. Practical & strategic gender interests have basic differences, just as the popular women's movement & the feminist movement have shown. A study of economic conditions reveals that the racial divide is still in force & that while the economic & social conditions of black women are close to those of black men, they are significantly below those of white women. Representation of women's interests since 1994 demonstrates the limitations of political representation, & a more gender transformative agenda is required if women are to move beyond false sisterhood & rhetoric. L. A. Hoffman JF - Feminist Studies AU - Mtintso, Thenjiwe AD - African National Congress Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 569 EP - 579 VL - 29 IS - 3 SN - 0046-3663, 0046-3663 KW - Sexual Inequality KW - Black White Relations KW - Feminism KW - South Africa KW - Political Representation KW - article KW - 9109: politics; political movements/activism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60698959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Feminist+Studies&rft.atitle=Representivity%3A+False+Sisterhood+or+Universal+Women%27s+Interests%3F+The+South+African+Experience&rft.au=Mtintso%2C+Thenjiwe&rft.aulast=Mtintso&rft.aufirst=Thenjiwe&rft.date=2003-10-01&rft.volume=29&rft.issue=3&rft.spage=569&rft.isbn=&rft.btitle=&rft.title=Feminist+Studies&rft.issn=00463663&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - FMSDA2 N1 - SubjectsTermNotLitGenreText - South Africa; Feminism; Political Representation; Sexual Inequality; Black White Relations ER - TY - JOUR T1 - Government Secrecy: Policy Depths and Dimensions AN - 60693772; 200409314 AB - Government secrecy has a long history in the American federal experience. Several kinds of government secrecy policy are reviewed here, beginning with their origins, or "policy depths," & extending to their most recent expressions or "dimensions." It is a rich history that, in this brief overview, is explored only in terms of its highlights, but offers, nonetheless, a roadmap for pursuing research in this area. It concludes with the observation that, in a democracy, representatives of the citizenry, whether elected or appointed, may momentarily cloak their decision making & their policies in secrecy for the good of the nation -- to protect it from enemies & to assure its survival. Those representatives must remember that the secrecy they impose is only momentary & that the shrouded decisions & policies they make, once made known to the citizenry, must be acceptable to them. The citizenry, in turn, should accept such secrecy only in limited instances & on a momentary basis in order to have the confidence that their representatives are making decisions & policies acceptable to them. A government failing to honor these arrangements may well be regarded as one "not worth the cost of preservation.". Adapted from the source document. JF - Government Information Quarterly AU - Relyea, Harold C AD - Library Congress, Congressional Research Service, Washington, DC HRELYEA@crs.loc.gov Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 395 EP - 418 VL - 20 IS - 4 SN - 0740-624X, 0740-624X KW - Policy Making KW - Secrecy KW - United States of America KW - National Security KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60693772?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Government+Information+Quarterly&rft.atitle=Government+Secrecy%3A+Policy+Depths+and+Dimensions&rft.au=Relyea%2C+Harold+C&rft.aulast=Relyea&rft.aufirst=Harold&rft.date=2003-10-01&rft.volume=20&rft.issue=4&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=Government+Information+Quarterly&rft.issn=0740624X&rft_id=info:doi/10.1016%2Fj.giq.2003.09.001 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - GIQUEU N1 - SubjectsTermNotLitGenreText - Secrecy; Policy Making; National Security; United States of America DO - http://dx.doi.org/10.1016/j.giq.2003.09.001 ER - TY - JOUR T1 - Deciding on War against Iraq: Institutional Failures AN - 60638340; 200404622 AB - Analyzes the performance of US political institutions in authorizing the war against Iraq in October 2002. The author finds that the Bush administration failed to provide correct information to Congress to justify the war & relied on tenuous claims that were discredited on many occasions. He also argues that Congress failed in its institutional duties both by voting on the Iraq resolution without sufficient evidence & by drafting the legislation in such a way that it left the power to initiate war in the hands of the President, exactly what the Framers had tried to prevent. Adapted from the source document. JF - Political Science Quarterly AU - Fisher, Louis AD - Congressional Research Service, Library Congress Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 389 EP - 410 VL - 118 IS - 3 SN - 0032-3195, 0032-3195 KW - Presidents KW - Checks and Balances KW - War KW - United States of America KW - Legislative Bodies KW - Institutions KW - Iraq KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60638340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Political+Science+Quarterly&rft.atitle=Deciding+on+War+against+Iraq%3A+Institutional+Failures&rft.au=Fisher%2C+Louis&rft.aulast=Fisher&rft.aufirst=Louis&rft.date=2003-10-01&rft.volume=118&rft.issue=3&rft.spage=389&rft.isbn=&rft.btitle=&rft.title=Political+Science+Quarterly&rft.issn=00323195&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States of America; War; Institutions; Checks and Balances; Presidents; Legislative Bodies; Iraq ER - TY - JOUR T1 - Synthesis and functions of water-soluble and thermosensitive copolymers having phosphonium groups from acryloyloxyethyl trialkyl phosphonium chloride, N-isopropylacrylamide, and without/with butylmethacrylate AN - 19810992; 8215459 AB - Water-soluble thermosensitive polymers were prepared by copolymerization of acryloyloxyethyl trialkyl phosphonium chlorides (AETRs) with having varying alkyl lengths, N-isopropylacrylamide (NIPAAm), and without/with butyl methacrylate (BMA). The relative viscosity of the solutions of the AETR-NIPAAm copolymers increased with increasing AETR content. The thermosensitivity of the AETR-NIPAAm copolymers was affected by an introduction of hydrophobic BMA into the copolymers and the thermosensitivity of the AETR-BMA-NIPAAm copolymers increased with chain length of alkyl groups in phosphonium groups in AETR. The AETR-NIPAAm copolymers and the AETR-BMA-NIPAAm copolymers had high flocculating ability against kaolin or bacteria such as Escherichia coli. The flocculating ability of the copolymers was affected with the AETR content, BMA content, and the chain length of alkyl groups in phosphonium groups. Almost 100% of the AETB-BMA-NIPAAm and AETO-BMA-NIPAAm copolymers dissolved in water could be recovered by heating the solution above 30°C in the presence of NaCl. JF - Journal of Applied Polymer Science AU - Nonaka, Takamasa AU - Li, Hua AU - Makinose, Kaku AU - Ogata, Tomonari AU - Kurihara, Seiji AD - Department of Applied Chemistry & Biochemistry, Faculty of Engineering, Kumamoto University, Kumamoto 860-8555, Japan, nonaka@gpo.kumamoto-u.ac.jp Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1139 EP - 1147 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk], [URL:http://www.wiley.com/] VL - 90 IS - 4 SN - 0021-8995, 0021-8995 KW - Microbiology Abstracts B: Bacteriology KW - Viscosity KW - Escherichia coli KW - Copolymers KW - Chloride KW - Hydrophobicity KW - Kaolin KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19810992?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Polymer+Science&rft.atitle=Synthesis+and+functions+of+water-soluble+and+thermosensitive+copolymers+having+phosphonium+groups+from+acryloyloxyethyl+trialkyl+phosphonium+chloride%2C+N-isopropylacrylamide%2C+and+without%2Fwith+butylmethacrylate&rft.au=Nonaka%2C+Takamasa%3BLi%2C+Hua%3BMakinose%2C+Kaku%3BOgata%2C+Tomonari%3BKurihara%2C+Seiji&rft.aulast=Nonaka&rft.aufirst=Takamasa&rft.date=2003-10-01&rft.volume=90&rft.issue=4&rft.spage=1139&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Polymer+Science&rft.issn=00218995&rft_id=info:doi/10.1002%2Fapp.12740 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Viscosity; Copolymers; Hydrophobicity; Chloride; Kaolin; Escherichia coli DO - http://dx.doi.org/10.1002/app.12740 ER - TY - JOUR T1 - Exercise training in chronic obstructive pulmonary disease AN - 19239471; 5812437 AB - Exercise and activity limitation are characteristic features of chronic obstructive pulmonary disease (COPD). Exercise intolerance may result from ventilatory limitation, cardiovascular impairment, and/or skeletal muscle dysfunction. Exercise training, a core component of pulmonary rehabilitation, improves the exercise capacity (endurance and, to a lesser degree, maximal work capacity) of patients with COPD in spite of the irreversible abnormalities in lung function. Dyspnea and health-related quality of life also improve following pulmonary rehabilitation. The clinical benefits of exercise rehabilitation last up to 2 years following 8 to 12 weeks of training. Existing evidence-based guidelines recommend that exercise training/pulmonary rehabilitation be included routinely in the management of patients with moderate to severe COPD. Exercise training/pulmonary rehabilitation may be undertaken in an inpatient, outpatient, or home-based setting, depending on the individual needs of the patient and available resources. The type and intensity of training and muscle groups trained determine the expected outcomes of exercise training. Both high- and low-intensity exercise lead to increased exercise endurance, but only high-intensity training also leads to physiologic gains in aerobic fitness. The rationale for and outcomes of lower- and upper-limb training, as well as ventilatory muscle training, are reviewed, and the potential for anabolic hormone supplementation to optimize the benefits of exercise training is discussed. JF - Journal of Rehabilitation Research and Development AU - Rochester, CL AD - Section of Pulmonary and Critical Care, Yale University School of Medicine, 300 Congress Avenue Building, Room S-441, New Haven, CT 06520, USA, carolyn.rochester@yale.edu Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 59 EP - 80 VL - 40 IS - 5 SN - 0748-7711, 0748-7711 KW - Physical Education Index KW - Rehabilitation KW - Lungs KW - Exercise (prescription) KW - Diseases KW - Exercise (programs) KW - Hormones KW - PE 110:Physical Therapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19239471?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Rehabilitation+Research+and+Development&rft.atitle=Exercise+training+in+chronic+obstructive+pulmonary+disease&rft.au=Rochester%2C+CL&rft.aulast=Rochester&rft.aufirst=CL&rft.date=2003-10-01&rft.volume=40&rft.issue=5&rft.spage=59&rft.isbn=&rft.btitle=&rft.title=Journal+of+Rehabilitation+Research+and+Development&rft.issn=07487711&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Exercise (prescription); Rehabilitation; Lungs; Diseases; Hormones; Exercise (programs) ER - TY - JOUR T1 - Peptide Surface Display and Secretion Using Two LPXTG-Containing Surface Proteins from Lactobacillus fermentum BR11 AN - 18941404; 5728933 AB - A locus encoding two repetitive proteins that have LPXTG cell wall anchoring signals from Lactobacillus fermentum BR11 has been identified by using an antiserum raised against whole L. fermentum BR11 cells. The first protein, Rlp, is similar to the Rib surface protein from Streptococcus agalactiae, while the other protein, Mlp, is similar to the mucus binding protein Mub from Lactobacillus reuteri. It was shown that multiple copies of mlp exist in the genome of L. fermentum BR11. Regions of Rlp, Mlp, and the previously characterized surface protein BspA were used to surface display or secrete heterologous peptides in L. fermentum. The peptides tested were 10 amino acids of the human cystic fibrosis transmembrane regulator protein and a six- histidine epitope (His sub(6)). The BspA promoter and secretion signal were used in combination with the Rlp cell wall sorting signal to express, export, and covalently anchor the heterologous peptides to the cell wall. Detection of the cell surface protein fusions revealed that Rlp was a significantly better surface display vector than BspA despite having lower cellular levels (0.7 mg per liter for the Rlp fusion compared with 4 mg per liter for the BspA fusion). The mlp promoter and encoded secretion signal were used to express and export large (328-kDa at 10 mg per liter) and small (27-kDa at 0.06 mg per liter) amino-terminal fragments of the Mlp protein fused to the His sub(6) and CFTR peptides or His sub(6) peptide, respectively. Therefore, these newly described proteins from L. fermentum BR11 have potential as protein production and targeting vectors. JF - Applied and Environmental Microbiology AU - Turner AU - Hafner, L M AU - Walsh, T AU - Giffard, P M AD - Infectious Diseases Program, Faculty of Science, Queensland University of Technology, G.P.O. Box 2434, Brisbane, Queensland 4001, Australia, ms.turner@qut.edu.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 5855 EP - 5863 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 69 IS - 10 SN - 0099-2240, 0099-2240 KW - man KW - BspA protein KW - CFTR protein KW - Rlp protein KW - mucus-binding protein KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Microbiology Abstracts B: Bacteriology KW - Cloning vectors KW - Lactobacillus fermentum KW - Lactobacillus reuteri KW - Streptococcus agalactiae KW - Peptides KW - Cystic fibrosis KW - Cell walls KW - W2 32340:Other peptides, proteins, amino acids KW - W 30965:Miscellaneous, Reviews KW - J 02727:Amino acids, peptides and proteins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18941404?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Peptide+Surface+Display+and+Secretion+Using+Two+LPXTG-Containing+Surface+Proteins+from+Lactobacillus+fermentum+BR11&rft.au=Turner%3BHafner%2C+L+M%3BWalsh%2C+T%3BGiffard%2C+P+M&rft.aulast=Turner&rft.aufirst=&rft.date=2003-10-01&rft.volume=69&rft.issue=10&rft.spage=5855&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.69.10.5855-5863.2003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Lactobacillus fermentum; Streptococcus agalactiae; Lactobacillus reuteri; Cell walls; Cloning vectors; Peptides; Cystic fibrosis DO - http://dx.doi.org/10.1128/AEM.69.10.5855-5863.2003 ER - TY - JOUR T1 - Ichthyotoxicity of Chattonella marina (Raphidophyceae) to damselfish (Acanthochromis polyacanthus): the synergistic role of reactive oxygen species and free fatty acids AN - 18881072; 5739100 AB - This investigation aimed to elucidate the relative roles of putative brevetoxins, reactive oxygen species and free fatty acids as the toxic principle of the raphidophyte Chattonella marina, using damselfish as the bioassay. Our investigations on Australian C. marina demonstrated an absence or only very low concentrations of brevetoxin-like compounds by radio-receptor binding assay and liquid chromatography-mass spectroscopy techniques. Chattonella is unique in its ability to produce levels of reactive oxygen species 100 times higher than most other algal species. However, high levels of superoxide on their own were found not to cause fish mortalities. Lipid analysis revealed this raphidophyte to contain high concentrations of the polyunsaturated fatty acid eicosapentaenoic acid (EPA; 18-23% of fatty acids), which has demonstrated toxic properties to marine organisms. Using damselfish as a model organism, we demonstrated that the free fatty acid (FFA) form of EPA produced a mortality and fish behavioural response similar to fish exposed to C. marina cells. This effect was not apparent when fish were exposed to other lipid fractions including a triglyceride containing fish oil, docosahexaenoate-enriched ethyl ester, or pure brevetoxin standards. The presence of superoxide together with low concentrations of EPA accelerated fish mortality rate threefold. We conclude that the enhancement of ichthyotoxicity of EPA in the presence of superoxide can account for the high C. marina fish killing potential. JF - Harmful Algae AU - Marshall, J-A AU - Nichols, P D AU - Hamilton, B AU - Lewis, R J AU - Hallegraeff, G M AD - School of Plant Science, University of Tasmania, G.P.O. Box 252-55, Hobart, Tasmania 7001, Australia, judi.marshall@utas.edu.au Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 273 EP - 281 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 2 IS - 4 SN - 1568-9883, 1568-9883 KW - Spotty-tail KW - eicosapentaenoic acid KW - free fatty acids KW - oxygen radicals KW - reactive oxygen species KW - superoxide KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Toxicology Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Ichthyotoxicity KW - Reactive oxygen species KW - Free fatty acids KW - Chattonella marina KW - Superoxide KW - Eicosapentaenoic acid KW - Noxious organisms KW - Marine KW - Synergism KW - Acanthochromis polyacanthus KW - Biological poisons KW - Free radicals KW - Phytoplankton KW - Australia Coasts KW - Toxicity KW - Toxins KW - Fish kill KW - Fatty acids KW - Polyunsaturated fatty acids KW - Raphidophyceae KW - Mortality causes KW - O 1070:Ecology/Community Studies KW - Q1 08483:Species interactions: general KW - K 03099:Pollution KW - Q1 08461:Plankton KW - Q1 08346:Physiology, biochemistry, biophysics KW - Q1 08226:Physiology, biochemistry, biophysics KW - X 24171:Microbial KW - O 1010:Viruses, Bacteria, Protists, Fungi and Plants KW - O 1050:Vertebrates, Urochordates and Cephalochordates UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18881072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harmful+Algae&rft.atitle=Ichthyotoxicity+of+Chattonella+marina+%28Raphidophyceae%29+to+damselfish+%28Acanthochromis+polyacanthus%29%3A+the+synergistic+role+of+reactive+oxygen+species+and+free+fatty+acids&rft.au=Marshall%2C+J-A%3BNichols%2C+P+D%3BHamilton%2C+B%3BLewis%2C+R+J%3BHallegraeff%2C+G+M&rft.aulast=Marshall&rft.aufirst=J-A&rft.date=2003-10-01&rft.volume=2&rft.issue=4&rft.spage=273&rft.isbn=&rft.btitle=&rft.title=Harmful+Algae&rft.issn=15689883&rft_id=info:doi/10.1016%2FS1568-9883%2803%2900046-5 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Noxious organisms; Fish kill; Synergism; Biological poisons; Polyunsaturated fatty acids; Phytoplankton; Toxicity; Mortality causes; Free radicals; Fatty acids; Toxins; Chattonella marina; Acanthochromis polyacanthus; Raphidophyceae; Australia Coasts; Marine DO - http://dx.doi.org/10.1016/S1568-9883(03)00046-5 ER - TY - JOUR T1 - Competition between Australian native and introduced grasses along a nutrient gradient AN - 18878794; 5730217 AB - Seven grass species were grown in monocultures and in multispecies mixtures along a gradient of total nutrient levels that ranged from 1/64 to 16 x the normal level of nutrient solution. The seven grasses represented three ecological groups: (i) three perennial species native to Australia (Themeda triandra, Poa labillardieri and Danthonia carphoides); (ii) two introduced annuals (Vulpia bromoides and Hordeum leporinum); and (iii) two introduced perennials (Lolium perenne and Dactylis glomerata). We hypothesized that the native grasses would prove less competitive when grown at increased nutrient levels than those introduced from Europe. Results supported the hypothesis. The native species were unable to compete in mixtures even at the lowest nutrient level, where T. triandra was the most productive species in monoculture. Lolium perenne and Dactylis glomerata dominated mixtures at intermediate nutrient levels. The responses of the annual introduced grasses differed in that Vulpia bromoides showed an optimum at intermediate nutrient levels in both monoculture and in mixtures, whereas Hordeum leporinum dominated at the highest nutrient levels in mixture but was suppressed by V. bromoides, L. perenne and D. glomerata at intermediate levels. The results are discussed in terms of predicting species responses in mixtures from their performance in monocultures as well as in terms of previous observations on the sequential changes in botanical composition of south-eastern Australian grasslands after 150 years of continuous grazing by sheep. JF - Austral Ecology AU - Groves, R H AU - Austin, M P AU - Kaye, P E AD - CSIRO Plant Industry, GPO Box 1600, Canberra, Australian Capital Territory 2601, Australia and CSIRO Sustainable Ecosystems, Canberra, Australian Capital Territory, Australia, richard.groves@csiro.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 491 EP - 498 PB - Blackwell Science Ltd VL - 28 IS - 5 SN - 1442-9985, 1442-9985 KW - Ecology Abstracts KW - D 04636:Grasses UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18878794?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Austral+Ecology&rft.atitle=Competition+between+Australian+native+and+introduced+grasses+along+a+nutrient+gradient&rft.au=Groves%2C+R+H%3BAustin%2C+M+P%3BKaye%2C+P+E&rft.aulast=Groves&rft.aufirst=R&rft.date=2003-10-01&rft.volume=28&rft.issue=5&rft.spage=491&rft.isbn=&rft.btitle=&rft.title=Austral+Ecology&rft.issn=14429985&rft_id=info:doi/10.1046%2Fj.1442-9993.2003.01305.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1046/j.1442-9993.2003.01305.x ER - TY - JOUR T1 - Vegetation indicators of salinity in northern Queensland AN - 18874195; 5730222 AB - The possibility that plants could serve as indicators of underlying soil salinity in northern Queensland, Australia, was investigated using 2197 site observations recorded during a land resources inventory of the Dalrymple Shire. The area surveyed intersects three biogeographical regions: the desert uplands, the Einasleigh uplands and the northern brigalow belt. The three dominant plant species in the lower, middle, and upper vegetation strata were recorded, along with laboratory measurements of electrical conductivity down each soil profile. Correspondence analysis, generalized additive models and clustering were used to investigate the relationship between plant occurrence, climatic and edaphic factors. The results of these statistical analyses strongly suggest a relationship between salinity and brigalow plant communities. A generalized additive model to predict soil salinity from environmental variables including vegetation data is presented. JF - Austral Ecology AU - Bui, EN AU - Henderson, B L AD - CSIRO Land and Water, Canberra, Australia Capital Territory, Australia, and CSIRO Mathematical and Information Sciences, GPO Box 664, Canberra, Australian Capital Territory 2601, Australia, brent.henderson@csiro.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 539 EP - 552 PB - Blackwell Science Ltd VL - 28 IS - 5 SN - 1442-9985, 1442-9985 KW - Ecology Abstracts KW - D 04001:Methodology - general UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18874195?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Austral+Ecology&rft.atitle=Vegetation+indicators+of+salinity+in+northern+Queensland&rft.au=Bui%2C+EN%3BHenderson%2C+B+L&rft.aulast=Bui&rft.aufirst=EN&rft.date=2003-10-01&rft.volume=28&rft.issue=5&rft.spage=539&rft.isbn=&rft.btitle=&rft.title=Austral+Ecology&rft.issn=14429985&rft_id=info:doi/10.1046%2Fj.1442-9993.2003.01311.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1046/j.1442-9993.2003.01311.x ER - TY - JOUR T1 - Degradation and recovery processes in arid grazing lands of central Australia. Part 1: soil and land resources AN - 18864834; 5714621 AB - The distribution and quality of soil and land resources in heterogeneous grazing lands of central Australia were changed by grazing. Sites located at increasing distances from livestock watering points showed greater degrees of landscape organization and soil productive potential. The depositional strata, where resources tended to accumulate, occupied a larger proportion of the landscape as distance increased. Physical and nutrient cycling soil properties improved. All soil chemistry variables except pH and electrical conductivity increased and the trend was most apparent in the top 1cm of the soil. Increasing erosion closer to water was a key degrading process. We showed degradation to be a systematic decline in regulation of scarce resources, which had implications for potential productivity. JF - Journal of Arid Environments AU - Tongway, D J AU - Sparrow, AD AU - Friedel, M H AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra ACT 2601, Australia, margaret.friedel@csiro.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 301 EP - 326 PB - Elsevier Science Ltd VL - 55 IS - 2 SN - 0140-1963, 0140-1963 KW - Ecology Abstracts KW - D 04712:Environmental degradation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18864834?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Arid+Environments&rft.atitle=Degradation+and+recovery+processes+in+arid+grazing+lands+of+central+Australia.+Part+1%3A+soil+and+land+resources&rft.au=Tongway%2C+D+J%3BSparrow%2C+AD%3BFriedel%2C+M+H&rft.aulast=Tongway&rft.aufirst=D&rft.date=2003-10-01&rft.volume=55&rft.issue=2&rft.spage=301&rft.isbn=&rft.btitle=&rft.title=Journal+of+Arid+Environments&rft.issn=01401963&rft_id=info:doi/10.1016%2FS0140-1963%2803%2900025-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0140-1963(03)00025-9 ER - TY - JOUR T1 - Returns and volatility on the Chinese stock markets AN - 18823306; 5735095 AB - The transfer of information is analysed within two distinct markets in the same country, specifically, the Chinese stock markets. The presence of autocorrelation and cross correlation in the four main stock indices is examined. The results for stock index data find spillovers in both directions from 'A' and 'B' shares. However, it is also documented that this feature of the market does not extend to volatility in that there is no spillover in volatility from 'B' share prices to 'A' share prices or vice-versa. JF - Applied Financial Economics AU - Brooks, R D AU - Ragunathan, V AD - Research Development Unit, RMIT Business, GPO Box 2476V, Melbourne, Vic. 3001, Australia Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 747 EP - 752 VL - 13 IS - 10 SN - 0960-3107, 0960-3107 KW - finance KW - information transfer KW - stock market KW - uncertainty KW - Risk Abstracts KW - R2 23070:Economics, organization UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18823306?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Financial+Economics&rft.atitle=Returns+and+volatility+on+the+Chinese+stock+markets&rft.au=Brooks%2C+R+D%3BRagunathan%2C+V&rft.aulast=Brooks&rft.aufirst=R&rft.date=2003-10-01&rft.volume=13&rft.issue=10&rft.spage=747&rft.isbn=&rft.btitle=&rft.title=Applied+Financial+Economics&rft.issn=09603107&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Heuristic and optimal solutions for set-covering problems in conservation biology AN - 18057859; 5777321 AB - Area-selection methods have recently gained prominence in conservation biology. A typical problem is to identify the minimum number of areas required to represent all species over some geographic region. Iterative heuristic methods have been developed by conservation scientists to solve these problems, although the solutions cannot be guaranteed to be optimal. Although optimal solutions can often be found, heuristics continue to be popular as they are perceived to be faster and more transparent as they are intuitively easy to understand. We used distributional data for 1921 bird species, 939 mammal species, 405 snake species, and 617 amphibian species compiled at the Zoological Museum, Univ. of Copenhagen for all 1 degree cells of mainland sub-Saharan Africa to compare the quality of the solutions found using two heuristic methods (simple-greedy algorithm and a progressive-rarity algorithm) with optimal solutions. We found that the heuristic methods considered here often provide solutions as good as optimal solutions. Even in those cases where the optimal solutions were better the difference was relatively small, with the heuristics providing solutions requiring a 2-10% increase in area selected compared with the optimal solution, which importantly, represented an increase of <1% of the total area. Our study also suggests that the heuristic algorithms performed least well for datasets with few single cell endemics and taxa that tend to have larger range sizes. Despite the good quality of solutions using heuristics there was no time penalty associated with finding optimal solutions for the problems considered here, suggesting that the major obstacle to their use is making optimal methods accessible to conservation biologists. We encourage conservation biologists to work with operations researchers and so gain the benefit of their expertise and experience in solving these kinds of problems. JF - Ecography AU - Moore, J L AU - Folkmann, M AU - Balmford, A AU - Brooks, T AU - Burgess, N AU - Rahbek, C AU - Williams, PH AU - Krarup, J AD - CSIRO Entomology, GPO Box 1700, Canberra ACT 2601, Australia, joslin.moore@csiro.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 595 EP - 601 VL - 26 IS - 5 SN - 0906-7590, 0906-7590 KW - Amphibians KW - Birds KW - Heuristics KW - Mammals KW - Reptiles KW - ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Marine KW - Q1 01362:Geographical distribution KW - D 04705:Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18057859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecography&rft.atitle=Heuristic+and+optimal+solutions+for+set-covering+problems+in+conservation+biology&rft.au=Moore%2C+J+L%3BFolkmann%2C+M%3BBalmford%2C+A%3BBrooks%2C+T%3BBurgess%2C+N%3BRahbek%2C+C%3BWilliams%2C+PH%3BKrarup%2C+J&rft.aulast=Moore&rft.aufirst=J&rft.date=2003-10-01&rft.volume=26&rft.issue=5&rft.spage=595&rft.isbn=&rft.btitle=&rft.title=Ecography&rft.issn=09067590&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Marine ER - TY - JOUR T1 - The Tropical Cyclone Risk in Cairns AN - 17598552; 5863253 AB - Because of its location close to a region of tropical cyclone formation, the city of Cairns is regularly affected by tropical cyclones. Most cyclones occur in the months January-March, although some have affected Cairns in December and April. There is a strong year-to-year variation in tropical cyclone numbers in the Cairns region, with twice as many impacts occurring during La Nina conditions as during El Nino. Several case studies are presented of cyclone impacts on Cairns. Rapidly developing cyclones are a particularly difficult forecast problem, as they can strike the city with less than 24 hours warning. Serious inundation from storm surge often occurs some time after landfall at Cairns. JF - Natural Hazards AU - Callaghan, J AD - Bureau of Meteorology, GPO Box 413, Brisbane, Queensland, 4001, Australia, J.Callaghan@bom.gov.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 129 EP - 153 VL - 30 IS - 2 SN - 0921-030X, 0921-030X KW - La Nina phenomena KW - cyclones KW - Meteorological & Geoastrophysical Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Risk Abstracts KW - M2 551.515.2:Cyclones Hurricanes Typhoons (551.515.2) KW - R2 23030:Natural hazards KW - Q2 02244:Air-sea coupling UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17598552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Natural+Hazards&rft.atitle=The+Tropical+Cyclone+Risk+in+Cairns&rft.au=Callaghan%2C+J&rft.aulast=Callaghan&rft.aufirst=J&rft.date=2003-10-01&rft.volume=30&rft.issue=2&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=Natural+Hazards&rft.issn=0921030X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - SuppNotes - Special Issue: Studies in community risk science: Cairns, Australia. N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - The Flood Risk in Cairns AN - 17595960; 5863254 AB - The Cairns region, on the north tropical coast of Queensland, forms part of the wettest area in Australia, with mean annual rainfalls of 2,000 to 4,000 mm. During the summer and early autumn months, intense rainfalls associated with cyclones and other tropical weather influences persist for several days, and can produce severe flooding in the Barron, Mulgrave and Russell Rivers and smaller drainage systems. There is often some loss of life and the damage to buildings, transport infrastructure, sugar cane and other agricultural crops can easily exceed $100 million. Very high intensity rainfalls over shorter periods, only a few hours, also present a significant urban flash flood risk, as happened at Townsville City, some 300 km to the south of Cairns, in January 1998. Despite the use of good floodplain management practices in recent decades, the combined risk of severe river floods and urban drainage floods is relatively high when compared with the other more damaging, but less frequent, natural hazards. JF - Natural Hazards AU - Baddiley, P AD - Bureau of Meteorology, Brisbane, GPO Box 413, Brisbane, Australia 4001, p.baddiley@bom.gov.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 155 EP - 164 VL - 30 IS - 2 SN - 0921-030X, 0921-030X KW - cyclones KW - Meteorological & Geoastrophysical Abstracts; Risk Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - M2 551.515.2:Cyclones Hurricanes Typhoons (551.515.2) KW - M2 556.166:Maximum runoff. Floods and flood runoff (556.166) KW - R2 23030:Natural hazards KW - SW 0835:Streamflow and runoff KW - Q2 02171:Dynamics of lakes and rivers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17595960?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Natural+Hazards&rft.atitle=The+Flood+Risk+in+Cairns&rft.au=Baddiley%2C+P&rft.aulast=Baddiley&rft.aufirst=P&rft.date=2003-10-01&rft.volume=30&rft.issue=2&rft.spage=155&rft.isbn=&rft.btitle=&rft.title=Natural+Hazards&rft.issn=0921030X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - SuppNotes - Special Issue: Studies in community risk science: Cairns, Australia. N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Polymorphic microsatellite markers for paternity assessment in southern calamari Sepioteuthis australis (Cephalopoda: Loliginidae) AN - 17276467; 5782935 AB - Recent decades have seen the fast growth of cephalopod fisheries but their management is compromised by the critical gaps in our knowledge of cephalopod life histories. Molecular markers are invaluable tools for studying the evolutionary significance and management implications of variation in mating systems. We have developed seven polymorphic microsatellite loci for mating system analysis in the southern calamari Sepioteuthis australis Quoy & Gaimard 1833 using magnetic enrichment and colony hybridization techniques. Observed heterozygosities range from 32% to 100% and will have sufficient power to examine the relative success of alternate mating strategies in S. australis. JF - Molecular Ecology Notes AU - Van Camp, LM AU - Saint, K M AU - Donnellan, S AU - Havenhand, J N AU - Fairweather, P G AD - School of Biological Sciences, Flinders University, GPO Box 2100, South Australia, 5001, Evolutionary Biology Unit, South Australian Museum, North Terrace, Adelaide, South Australia, 5000, lissa.vancamp@flinders.edu.au Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 654 EP - 655 PB - Blackwell Science Ltd VL - 3 IS - 4 SN - 1471-8278, 1471-8278 KW - Cephalopods KW - Squids KW - ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts; Genetics Abstracts KW - Marine KW - Loliginidae KW - Nucleotide sequence KW - Cephalopod fisheries KW - Microsatellites KW - Cephalopoda KW - Genotypes KW - Biomarkers KW - Biopolymorphism KW - Reproductive strategy KW - Population genetics KW - Life history KW - Sepioteuthis australis KW - Fisheries KW - Genetic markers KW - DNA KW - Marine molluscs KW - Reproductive behaviour KW - D 04658:Molluscs KW - G 07270:Ecological genetics KW - Q1 08265:Genetics and evolution KW - G 07364:Mollusks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17276467?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+Ecology+Notes&rft.atitle=Polymorphic+microsatellite+markers+for+paternity+assessment+in+southern+calamari+Sepioteuthis+australis+%28Cephalopoda%3A+Loliginidae%29&rft.au=Van+Camp%2C+LM%3BSaint%2C+K+M%3BDonnellan%2C+S%3BHavenhand%2C+J+N%3BFairweather%2C+P+G&rft.aulast=Van+Camp&rft.aufirst=LM&rft.date=2003-10-01&rft.volume=3&rft.issue=4&rft.spage=654&rft.isbn=&rft.btitle=&rft.title=Molecular+Ecology+Notes&rft.issn=14718278&rft_id=info:doi/10.1046%2Fj.1471-8286.2003.00549.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Population genetics; Cephalopod fisheries; Nucleotide sequence; DNA; Marine molluscs; Biomarkers; Genotypes; Reproductive behaviour; Biopolymorphism; Life history; Genetic markers; Fisheries; Microsatellites; Reproductive strategy; Loliginidae; Sepioteuthis australis; Cephalopoda; Marine DO - http://dx.doi.org/10.1046/j.1471-8286.2003.00549.x ER - TY - JOUR T1 - The analysis of polar fractions from sediment extracts and crude oils using reaction-gas chromatography-mass spectrometry AN - 16168687; 5739364 AB - Reaction-gas chromatography-mass spectrometry (R-GC-MS) has been used to analyse the polar fractions of sediment extracts and crude oils. Functionalised species were hydrogenolysed in the presence of hydrogen carrier gas, over a palladium black catalyst contained within the vapourising injector of a gas chromatograph-mass spectrometer. Model compound studies showed that the fully active catalyst was effective in hydrogenating and isomerising alkenes, partially hydrogenating aromatic moieties and desulfurising thiols, sulfides, and thiophenes. Primary alcohols, acids, esters and ethers were defunctionalised to produce hydrocarbons with one carbon atom fewer than the reactant, while secondary alcohols were reduced to the parent hydrocarbon. The R-GC-MS analysis of the polar fractions of the Heartbreak Ridge lignite (Bremer Basin, Western Australia; Eocene age) and the Monterey Formation shale (Naples Beach, USA; Miocene age) extracts produced biomarker hydrocarbons which had lost their biological stereochemistry, but nonetheless reflected organic matter sources. In contrast, R-GC-MS analysis of the polar fractions from Exxon Program crude oils released lesser amounts of very similar, non-specific hydrocarbons. Thus the majority of the components of thermally mature polar fractions, as well as asphaltenes, do not react under the selected R-GC-MS conditions. Although less specific than traditional chemical degradation techniques, R-GC-MS affords a rapid and detailed molecular analysis of small quantities of sample that will be of particular use for characterising immature complex polar mixtures. JF - Organic Geochemistry AU - Sandison, C M AU - Alexander, R AU - Kagi, R I AD - Centre for Petroleum and Environmental Organic Geochemistry, School of Applied Chemistry, Curtin University of Technology, GPO Box U1987, Perth, WA 6001, Australia, carolyn.sandison@ga.gov.au Y1 - 2003/10// PY - 2003 DA - October 2003 SP - 1373 EP - 1389 PB - Pergamon VL - 34 IS - 10 SN - 0146-6380, 0146-6380 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - Mass Spectrometry KW - Chemical degradation KW - Hydrocarbons KW - Organic matter KW - Geochemistry KW - Alkenes KW - Hydrogen KW - Biomarkers KW - Esters KW - Gas Chromatography KW - Sediments KW - Carbon KW - Crude oil KW - Organic Matter KW - Ethers KW - Chemical Degradation KW - Aromatics KW - Spectrometers KW - SW 3010:Identification of pollutants KW - Q2 09187:Geochemistry of sediments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16168687?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Organic+Geochemistry&rft.atitle=The+analysis+of+polar+fractions+from+sediment+extracts+and+crude+oils+using+reaction-gas+chromatography-mass+spectrometry&rft.au=Sandison%2C+C+M%3BAlexander%2C+R%3BKagi%2C+R+I&rft.aulast=Sandison&rft.aufirst=C&rft.date=2003-10-01&rft.volume=34&rft.issue=10&rft.spage=1373&rft.isbn=&rft.btitle=&rft.title=Organic+Geochemistry&rft.issn=01466380&rft_id=info:doi/10.1016%2FS0146-6380%2803%2900156-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-03-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Chemical degradation; Crude oil; Hydrocarbons; Organic matter; Alkenes; Geochemistry; Biomarkers; Esters; Aromatics; Sediments; Mass Spectrometry; Carbon; Organic Matter; Chemical Degradation; Hydrogen; Ethers; Gas Chromatography; Spectrometers DO - http://dx.doi.org/10.1016/S0146-6380(03)00156-6 ER - TY - JOUR T1 - Prenatal PCB Exposure, the Corpus Callosum, and Response Inhibition AN - 14674530; 10650978 AB - Subjects enrolled in the Oswego Newborn and Infant Development Project, a prospective, longitudinal study of the neurobehavioral correlates of PCBs in mothers and children in the Great Lakes region, were used to determine if any putative PCB-related deficits in response inhibition were associated with the morphometric changes in the posterior corpus collosum seen typically in disorders associated with impulse behavior. The children were recruited at birth from 1991 through 1994, and a version of the continuous performance test called the Michigan Catch-the-Cat test was employed. Approximately 24 months after the last child was tested, MRI scans were conducted on 60 subjects consisting of 30 most exposed to PCBs and 30 least exposed. A correlative relationship was found between prenatal PCB exposure and poorer response inhibition in children. The size of the splenium was the major predictor of errors of commission, with smaller splenium volumes associated with greater errors of commission. JF - Environmental Health Perspectives AU - Stewart, Paul AU - Fitzgerald, Susan AU - Reihman, Jacqueline AU - Gump, Brooks AU - Lonky, Edward AU - Darvill, Thomas AU - Pagano, Jim Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1670 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - NEUROTOXICITY KW - PSYCHOLOGICAL EFFECTS KW - DOSE RESPONSE PROFILES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14674530?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prenatal+PCB+Exposure%2C+the+Corpus+Callosum%2C+and+Response+Inhibition&rft.au=Stewart%2C+Paul%3BFitzgerald%2C+Susan%3BReihman%2C+Jacqueline%3BGump%2C+Brooks%3BLonky%2C+Edward%3BDarvill%2C+Thomas%3BPagano%2C+Jim&rft.aulast=Stewart&rft.aufirst=Paul&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1670&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PSYCHOLOGICAL EFFECTS; NEUROTOXICITY; POLYCHLORINATED BIPHENYLS; DOSE RESPONSE PROFILES ER - TY - JOUR T1 - Time Trends of Persistent Organic Pollutants and Heavy Metals in Umbilical Cord Blood of Inuit Infants Born in Nunavik (Quebec, Canada) Between 1994 and 2001 AN - 14674495; 10650976 AB - Participants of two previous studies done on the same Inuit population were used to examine the temporal trends in concentrations of persistent organic pollutants and heavy metals in umbilical cord blood over the period 19942001. The participants lived in three communities on the coast of Hudson Bay in Nunavik, PQ, Canada. An exponential decrease in most of the contaminants analyzed was identified. Significant decreases over time were found in the concentrations of PCB congeners, p,p'-DDE and -DDT, mercury, and lead. JF - Environmental Health Perspectives AU - Dallaire, Frederic AU - Dewailly, Eric AU - Muckle, Gina AU - Ayotte, Pierre Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1660 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - QUEBEC PROVINCE KW - ORGANOCHLORINE PESTICIDES KW - BIOACCUMULATION, HUMAN KW - BLOOD ANALYSIS KW - INDIGENOUS PEOPLE KW - REPRODUCTION, HUMAN KW - HEAVY METALS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14674495?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Time+Trends+of+Persistent+Organic+Pollutants+and+Heavy+Metals+in+Umbilical+Cord+Blood+of+Inuit+Infants+Born+in+Nunavik+%28Quebec%2C+Canada%29+Between+1994+and+2001&rft.au=Dallaire%2C+Frederic%3BDewailly%2C+Eric%3BMuckle%2C+Gina%3BAyotte%2C+Pierre&rft.aulast=Dallaire&rft.aufirst=Frederic&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1660&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; INDIGENOUS PEOPLE; HEAVY METALS; REPRODUCTION, HUMAN; QUEBEC PROVINCE; BIOACCUMULATION, HUMAN; ORGANOCHLORINE PESTICIDES; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Hearing Loss in Workers Exposed to Carbon Disulfide and Noise AN - 14674438; 10650970 AB - Hearing loss was evaluated in workers exposed simultaneously to carbon disulfide and noise, and compared with subjects exposed to noise only and those exposed to low noise and no CS sub(2). The subjects exposed to both CS sub(2) and noise worked in two plants manufacturing viscose rayon. All three groups were given a pure-tone audiometry test for hearing thresholds of air conduction to both ears. The prevalence of hearing loss of greater than or equal to 25 dB hearing loss was greater in the viscose rayon workers compared to the other two groups. A CS sub(2) doseresponse association was found after controlling for age, smoking, drinking, and the use of noise-proof equipment. JF - Environmental Health Perspectives AU - Chang, Shu-Ju AU - Shih, Tung-Sheng AU - Chou, Tzu-Chieh AU - Chen, Chiou-Jong AU - Chang, Ho-Yuan AU - Sung, Fung-Chang Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1620 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEARING LOSS KW - CARBON DISULFIDE KW - HEALTH SAFETY, OCCUPATIONAL KW - NOISE EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14674438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Hearing+Loss+in+Workers+Exposed+to+Carbon+Disulfide+and+Noise&rft.au=Chang%2C+Shu-Ju%3BShih%2C+Tung-Sheng%3BChou%2C+Tzu-Chieh%3BChen%2C+Chiou-Jong%3BChang%2C+Ho-Yuan%3BSung%2C+Fung-Chang&rft.aulast=Chang&rft.aufirst=Shu-Ju&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1620&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; CARBON DISULFIDE; HEARING LOSS; NOISE EFFECTS ER - TY - JOUR T1 - Antibiotics in Dust Originating from a Pig-Fattening Farm: a New Source of Health Hazard for Farmers? AN - 14674408; 10650965 AB - Sedimentation dust samples collected over the period 19812000 at a pig-fattening farm were analyzed for the presence of antibiotics. The samples had been collected each year over periods ranging 1430 d. Up to five different antibiotics at concentrations ranging 0.212.5 mg/kg were found in 18 of 20 samples. Tylosin was detected most often and at the highest concentrations. Sulfamethazine, chloramphenicol, and several tetracyclines were also detected. While the resulting local concentration of antibiotics in the lung was far too low for any bacteriocidal or bacteriostatic effect, prolonged exposure could result in the development of antibiotic resistance. JF - Environmental Health Perspectives AU - Hamscher, Gerd AU - Pawelzick, Heike Theresia AU - Sczesny, Silke AU - Nau, Heinz AU - Hartung, Jorg Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1590 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SWINE KW - RESPIRABLE DUST KW - ANTIBIOTICS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14674408?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Antibiotics+in+Dust+Originating+from+a+Pig-Fattening+Farm%3A+a+New+Source+of+Health+Hazard+for+Farmers%3F&rft.au=Hamscher%2C+Gerd%3BPawelzick%2C+Heike+Theresia%3BSczesny%2C+Silke%3BNau%2C+Heinz%3BHartung%2C+Jorg&rft.aulast=Hamscher&rft.aufirst=Gerd&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1590&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SWINE; ANTIBIOTICS; RESPIRABLE DUST ER - TY - JOUR T1 - Associations of Renal Function with Polymorphisms in the delta -Aminolevulinic Acid Dehydratase, Vitamin D Receptor, and Nitric Oxide Synthase Genes in Korean Lead Workers AN - 14673740; 10650969 AB - Data obtained from 798 current and former lead workers in Korea were used to examine the associations of delta -aminolevulinic acid dehydratase (ALAD), endothelial nitric oxide synthase (eNOS), and the vitamin D receptor (VDR) with Pb exposure and dose measures with renal outcomes. The Pb biomarkers and renal outcomes were measured using previously reported assays, which are outlined. The renal outcomes included: blood urea nitrogen (BUN), serum creatinine, measured creatinine clearance, calculated creatinine clearance, retinol-binding protein (RBP), and N-acetyl- beta -D-glucosaminidase. After adjustment, participants with the ALAD super(2) allele had lower mean serum creatinine and higher calculated creatinine clearance. Higher Pb exposure dose was associated with lower BUN, serum creatinine, and RBP but higher creatinine clearance in participants with the ALAD super(2) genotype. Few significant results were found for the eNOS and VDR genotypes, although participants with the eNOS Asp allele had higher measured creatinine clearance and higher BUN. JF - Environmental Health Perspectives AU - Weaver, Virginia M AU - Schwartz, Brian S AU - Ahn, Kyu-Dong AU - Stewart, Walter F AU - Kelsey, Karl T AU - Todd, Andrew C AU - Wen, Jiayu Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1613 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - LEAD KW - GENETICS, HUMAN KW - NEPHROTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Associations+of+Renal+Function+with+Polymorphisms+in+the+delta+-Aminolevulinic+Acid+Dehydratase%2C+Vitamin+D+Receptor%2C+and+Nitric+Oxide+Synthase+Genes+in+Korean+Lead+Workers&rft.au=Weaver%2C+Virginia+M%3BSchwartz%2C+Brian+S%3BAhn%2C+Kyu-Dong%3BStewart%2C+Walter+F%3BKelsey%2C+Karl+T%3BTodd%2C+Andrew+C%3BWen%2C+Jiayu&rft.aulast=Weaver&rft.aufirst=Virginia&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1613&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; LEAD; GENETICS, HUMAN; NEPHROTOXICITY ER - TY - JOUR T1 - Historical Pesticide Exposure in California Using Pesticide Use Reports and Land-Use Surveys: an Assessment of Misclassification Error and Bias AN - 14673698; 10650964 AB - California's Pesticide Use Reports and land-use survey databases were used to conduct a simulation study of the potential consequences of misclassifying residential exposure due to proximity to agricultural pesticide application in health effect studies. Simulations were conducted using only the land-use information and only the Pesticide Use Reports. Data from Kern County were used, which is the second most agriculturally productive county in the US. The respective sensitivities and specificities of a broad and narrow zonal exposure definition were calculated and compared to the exposure classification derived from the combined reports and land-use model. Results showed that the effect estimates were less attenuated if exposure status for a residence was defined using a smaller and more restricted geographic area yielding 100% specificity rather than relying on a larger area to increase sensitivity. Nondifferential exposure misclassification increased with the residential mobility rate and prevalence of exposure in the population. JF - Environmental Health Perspectives AU - Rull, Rudolph P AU - Ritz, Beate Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1582 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DATA, PEST CONTROL KW - LAND USE CLASSIFICATION KW - RISK ASSESSMENT KW - CALIFORNIA KW - GEOGRAPHIC INFORMATION SYSTEMS KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673698?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Historical+Pesticide+Exposure+in+California+Using+Pesticide+Use+Reports+and+Land-Use+Surveys%3A+an+Assessment+of+Misclassification+Error+and+Bias&rft.au=Rull%2C+Rudolph+P%3BRitz%2C+Beate&rft.aulast=Rull&rft.aufirst=Rudolph&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1582&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; LAND USE CLASSIFICATION; CALIFORNIA; GEOGRAPHIC INFORMATION SYSTEMS; DATA, PEST CONTROL; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Acute Occupational Disinfectant-Related Illness Among Youth, 19931998 AN - 14672446; 10650975 AB - Data on all children 17 yr old or younger and adults 2544 yr old who developed acute disinfectant-related illnesses occupationally were examined to assess the magnitude, incidence, and nature of acute occupational disinfectant-related illness. The data, which covered the period 199398, were from the Toxic Exposure Surveillance System and the California Department of Pesticide Regulation. Average annual incidence rates of 16.8 and 4.14 acute disinfectant-related illnesses per billion hours worked for working youths and adults, respectively, were found. Compared to adults, the use of personal protective equipment among youths was low. JF - Environmental Health Perspectives AU - Brevard, Theresa A AU - Calvert, Geoffrey M AU - Blondell, Jerome M AU - Mehler, Louise N Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1654 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - DISEASES AND DISORDERS KW - CHEMICAL CONTAMINATION KW - AGE COMPARISONS KW - DISINFECTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Acute+Occupational+Disinfectant-Related+Illness+Among+Youth%2C+1993%26lt%3BND%26gt%3B1998&rft.au=Brevard%2C+Theresa+A%3BCalvert%2C+Geoffrey+M%3BBlondell%2C+Jerome+M%3BMehler%2C+Louise+N&rft.aulast=Brevard&rft.aufirst=Theresa&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1654&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; DISEASES AND DISORDERS; CHEMICAL CONTAMINATION; DISINFECTION; AGE COMPARISONS ER - TY - JOUR T1 - Assessing the Effects of Endocrine Disruptors in the National Children's Study AN - 14672445; 10650979 AB - An overview is provided of reports that emerged from a workshop convened to examine the effects of endocrine disruptors on child development that may be observed in the National Children's Study, which is examining the influences of early exposures on human development and on child and adult health. The study will follow as many as 100,000 children in all regions of the US from early pregnancy to 21 yr of age. The reports pertain to the rationale for studying children, the rationale for studying endocrine disruptors in the larger study, the evidence of endocrine disruption found in previous studies, and the potential relevance of endocrine disruptors to children's health. JF - Environmental Health Perspectives AU - Landrigan, Philip AU - Garg, Anjali AU - Droller, Daniel BJ Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1678 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PATHOLOGY, CHILDREN KW - HORMONAL EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672445?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessing+the+Effects+of+Endocrine+Disruptors+in+the+National+Children%27s+Study&rft.au=Landrigan%2C+Philip%3BGarg%2C+Anjali%3BDroller%2C+Daniel+BJ&rft.aulast=Landrigan&rft.aufirst=Philip&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1678&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 56 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PATHOLOGY, CHILDREN; HORMONAL EFFECTS ER - TY - JOUR T1 - Measurement of Brevetoxin Levels by Radioimmunoassay of Blood Collection Cards After Acute, Long-Term, and Low-Dose Exposure in Mice AN - 14672419; 10650966 JF - Environmental Health Perspectives AU - Woofter, Ricky AU - Dechraoui, M-Yasmine Bottein AU - Garthwaite, Ian AU - Towers, Neale R AU - Gordon, Christopher J AU - Cordova, Jose AU - Ramsdell, John S Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1595 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - BLOOD ANALYSIS KW - TOXIC SUBSTANCES KW - RED TIDE KW - IMMUNOASSAY TESTING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Measurement+of+Brevetoxin+Levels+by+Radioimmunoassay+of+Blood+Collection+Cards+After+Acute%2C+Long-Term%2C+and+Low-Dose+Exposure+in+Mice&rft.au=Woofter%2C+Ricky%3BDechraoui%2C+M-Yasmine+Bottein%3BGarthwaite%2C+Ian%3BTowers%2C+Neale+R%3BGordon%2C+Christopher+J%3BCordova%2C+Jose%3BRamsdell%2C+John+S&rft.aulast=Woofter&rft.aufirst=Ricky&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1595&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; BLOOD ANALYSIS; TOXIC SUBSTANCES; RED TIDE; IMMUNOASSAY TESTING ER - TY - JOUR T1 - An Approach to Assessment of Endocrine Disruption in the National Children's Study AN - 14672035; 10650981 AB - The National Children's Study will be a multi-center study of at least 100,000 children who will be followed from before birth to 21 yr of age. The precise design of the study has not yet been specified. Here, the importance of assessing endocrine disruption in the study is considered. Evidence that alterations of the early, normal endocrine environment has adverse effects is reviewed briefly, and the need for assessment of endocrine disruption in the National Children's Study is explored. Selected earlier cohort studies of children's health are elucidated, which could serve as reference points for the design of the National Children's Study, focusing on an improved assessment of the societal context, use of an intergenerational design, linkage to other data sources, the addition of selected exposure and outcome measures, and the use of genomics and proteomics. JF - Environmental Health Perspectives AU - Longnecker, Matthew P AU - Bellinger, David C AU - Crews, David AU - Eskenazi, Brenda AU - Silbergeld, Ellen K AU - Woodruff, Tracey J AU - Susser, Ezra S Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1691 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - PATHOLOGY, CHILDREN KW - HORMONAL EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672035?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=An+Approach+to+Assessment+of+Endocrine+Disruption+in+the+National+Children%27s+Study&rft.au=Longnecker%2C+Matthew+P%3BBellinger%2C+David+C%3BCrews%2C+David%3BEskenazi%2C+Brenda%3BSilbergeld%2C+Ellen+K%3BWoodruff%2C+Tracey+J%3BSusser%2C+Ezra+S&rft.aulast=Longnecker&rft.aufirst=Matthew&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1691&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 121 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; PATHOLOGY, CHILDREN; HORMONAL EFFECTS ER - TY - JOUR T1 - Cumulative Organophosphate Pesticide Exposure and Risk Assessment Among Pregnant Women Living in an Agricultural Community: a Case Study from the CHAMACOS Cohort AN - 14672010; 10650973 AB - The EPA cumulative risk assessment guidelines were used to examine potential health risks to pregnant women participating in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS> study, which was conducted in an agricultural area of California. All of the women had detectable levels of urinary organophosphate pesticide metabolites at some point in their pregnancy. Urine samples were collected from the women twice during pregnancy, at approximately 14 and 26 weeks of gestation, and then after delivery. Two methods, which are described, were used to estimate organophosphate pesticide doses from the urinary metabolite concentration data: one assumed exposure to a single pesticide, and the second assumed exposure to a mixture of pesticides. EPA oral benchmark dose sub(10) values were used as the measure of toxic potency to calculate organophosphate pesticide relative potency factors, which were derived from doseresponse curves from studies of brain cholinesterase inhibition in female rats. Results indicated that a small portion of the pregnant women may have cumulative organophosphate pesticide exposures exceeding a health-protective reference value. JF - Environmental Health Perspectives AU - Castorina, Rosemary AU - Bradman, Asa AU - McKone, Thomas E AU - Barr, Dana B AU - Harnly, Martha E AU - Eskenazi, Brenda Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1640 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSIMETRY KW - PREGNANCY KW - AGRICULTURAL CHEMICALS KW - BIOACCUMULATION, HUMAN KW - RISK ASSESSMENT KW - CALIFORNIA KW - ORGANOPHOSPHATE PESTICIDES KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672010?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cumulative+Organophosphate+Pesticide+Exposure+and+Risk+Assessment+Among+Pregnant+Women+Living+in+an+Agricultural+Community%3A+a+Case+Study+from+the+CHAMACOS+Cohort&rft.au=Castorina%2C+Rosemary%3BBradman%2C+Asa%3BMcKone%2C+Thomas+E%3BBarr%2C+Dana+B%3BHarnly%2C+Martha+E%3BEskenazi%2C+Brenda&rft.aulast=Castorina&rft.aufirst=Rosemary&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1640&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DOSIMETRY; CALIFORNIA; ORGANOPHOSPHATE PESTICIDES; PREGNANCY; AGRICULTURAL CHEMICALS; PESTICIDE EXPOSURE; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Age- and Sex-Dependent Distribution of Persistent Organochlorine Pollutants in Urban Foxes AN - 14671977; 10650968 AB - Red foxes Vulpes vulpes were collected between January 1999 and February 2000 in Zurich, Switzerland, and its suburbs, and the distribution of organochlorines was analyzed. Organochlorine concentrations were assessed in samples of homogenized kidney. The animals were divided into three age groups: juvenile, young, and adult. The quantitatively most important residue fraction consisted of PCBs, with congeners 138, 153, and 180 constituting the dominating components in all animals. A gradient of PCB concentrations was observed in adipose tissue from the urban foxes to animals living in the suburbs and rural surroundings. The PCB burden in the animals decreased with age, whereas the burdens of DDT, endosulfan, hexachlorobenzene, and heptachlor epoxide did not differ significantly among the different age groups. JF - Environmental Health Perspectives AU - Dip, Ramiro AU - Hegglin, Daniel AU - Deplazes, Peter AU - Dafflon, Oscar AU - Koch, Herbert AU - Naegeli, Hanspeter Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1608 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOACCUMULATION, ANIMAL KW - POLYCHLORINATED BIPHENYLS KW - BIOLOGICAL INDICATORS KW - SPATIAL COMPARISONS KW - AGE COMPARISONS KW - ORGANOCHLORINE PESTICIDES KW - FOXES KW - SWITZERLAND KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Age-+and+Sex-Dependent+Distribution+of+Persistent+Organochlorine+Pollutants+in+Urban+Foxes&rft.au=Dip%2C+Ramiro%3BHegglin%2C+Daniel%3BDeplazes%2C+Peter%3BDafflon%2C+Oscar%3BKoch%2C+Herbert%3BNaegeli%2C+Hanspeter&rft.aulast=Dip&rft.aufirst=Ramiro&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1608&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOACCUMULATION, ANIMAL; FOXES; POLYCHLORINATED BIPHENYLS; BIOLOGICAL INDICATORS; SWITZERLAND; SPATIAL COMPARISONS; AGE COMPARISONS; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Integrated Pest Management in an Urban Community: a Successful Partnership for Prevention AN - 14671975; 10650974 AB - Results are presented from a study in which integrated pest management was implemented successfully in East Harlem, NY. The study design utilized a two-armed prevention intervention trial designed to test whether integrated pest management techniques and targeted education at the household level could reduce cockroach infestation and exposure to chemical pesticides. Each intervention participant received an individually tailored integrated pest management program with a range of services, including: education and instruction in nontoxic integrated pest management methods by a health educator, instructions for better housekeeping and sanitation, repair services to seal cracks and crevices, fixing plumbing leaks, least-toxic supplies, expert advice from pest-control experts, and advocacy with building management to introduce safe pest-control practices. The results show that the frequency of cockroach infestation in the integrated pest management households declined by more than 50% over the six months of the study, while levels in the control households remained unchanged. JF - Environmental Health Perspectives AU - Brenner, Barbara L AU - Markowitz, Steven AU - Rivera, Maribel AU - Romero, Harry AU - Weeks, Matthew AU - Sanchez, Elizabeth AU - Deych, Elena Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1649 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - INTEGRATED CONTROL, PESTS KW - INNER CITY KW - COCKROACHES KW - EDUCATION, PUBLIC KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671975?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Integrated+Pest+Management+in+an+Urban+Community%3A+a+Successful+Partnership+for+Prevention&rft.au=Brenner%2C+Barbara+L%3BMarkowitz%2C+Steven%3BRivera%2C+Maribel%3BRomero%2C+Harry%3BWeeks%2C+Matthew%3BSanchez%2C+Elizabeth%3BDeych%2C+Elena&rft.aulast=Brenner&rft.aufirst=Barbara&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1649&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - INTEGRATED CONTROL, PESTS; INNER CITY; COCKROACHES; EDUCATION, PUBLIC ER - TY - JOUR T1 - Short-Term Exposure of Chinook Salmon (Oncoryhnchus tshawytscha) to o,p'-DDE or DMSO During Early Life-History Stages Causes Long-Term Humoral Immunosuppression AN - 14671951; 10650967 AB - Chinook salmon Oncoryhnchus tshawytscha eggs were exposed to dimethyl sulfoxide (DMSO) vehicle alone and with increasing concentrations of o,p'-DDE, and effects on immune function were monitored over time. Results revealed that brief exposure to a low dose of o,p'-DDE during early life stages had a long-term effect on the immune function. The early brief exposure was sufficient to significantly reduce the humoral response of juvenile fish to a mitogen 1 yr later. One year after the first feeding, o,p'-DDE was detected in the muscle tissue of juveniles for all treatments. The data also suggested that DMSO alone may have altered the development of the immune system. No effect of o,p'-DDE was noted in terms of mortality, time to hatch, sex ratio, gonadal development, plasma lysozyme concentration, or leukocyte mitogenesis. JF - Environmental Health Perspectives AU - Milston, Ruth H AU - Fitzpatrick, Martin S AU - Vella, Anthony T AU - Clements, Shaun AU - Gundersen, Deke AU - Feist, Grant AU - Crippen, Tawni L Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1601 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - IMMUNOSUPPRESSION KW - SALMON KW - DDE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Short-Term+Exposure+of+Chinook+Salmon+%28Oncoryhnchus+tshawytscha%29+to+o%2Cp%27-DDE+or+DMSO+During+Early+Life-History+Stages+Causes+Long-Term+Humoral+Immunosuppression&rft.au=Milston%2C+Ruth+H%3BFitzpatrick%2C+Martin+S%3BVella%2C+Anthony+T%3BClements%2C+Shaun%3BGundersen%2C+Deke%3BFeist%2C+Grant%3BCrippen%2C+Tawni+L&rft.aulast=Milston&rft.aufirst=Ruth&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1601&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - IMMUNOSUPPRESSION; SALMON; DDE ER - TY - JOUR T1 - Embracing the Local: Enriching Scientific Research, Education, and Outreach on the TexasMexico Border Through a Participatory Action Research Partnership AN - 14671765; 10650962 AB - In 1999, an environmental health education and outreach program was initiated in Cameron Park, TX, by the Texas A&M University Center for Housing and Urban Development Colonias Program and the Center for Environmental and Rural Health. Cameron Park is one of many unincorporated, irregular rural settlements along the TexasMexico border that lack water, sewer, and improved roads. More than half of the households live below the poverty level. The aim of the Cameron Park Project was the provide environmental health education based on scientific information and best practices for preventive health care and to assess the state of knowledge among residents before and after the project. An overview is provided of the methodological challenges presented by such a project, focusing on finding a methodology that provided reliable communication with wary residents. Ultimately, a research methodology called participatory action research was adopted, which is constructed on four integrated processes-planning, action, observation, and reflection-that continue in successive cycles until research objectives are achieved. JF - Environmental Health Perspectives AU - May, Marlynn L AU - Bowman, Gloria J AU - Ramos, Kenneth S AU - Rincones, Larry AU - Rebollar, Maria G AU - Rosa, Mary L AU - Saldana, Josephine Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1571 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - TEXAS KW - PUBLIC HEALTH KW - PUBLIC PARTICIPATION KW - EDUCATION, PUBLIC KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Embracing+the+Local%3A+Enriching+Scientific+Research%2C+Education%2C+and+Outreach+on+the+Texas%26lt%3BND%26gt%3BMexico+Border+Through+a+Participatory+Action+Research+Partnership&rft.au=May%2C+Marlynn+L%3BBowman%2C+Gloria+J%3BRamos%2C+Kenneth+S%3BRincones%2C+Larry%3BRebollar%2C+Maria+G%3BRosa%2C+Mary+L%3BSaldana%2C+Josephine&rft.aulast=May&rft.aufirst=Marlynn&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1571&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - TEXAS; PUBLIC HEALTH; PUBLIC PARTICIPATION; EDUCATION, PUBLIC ER - TY - JOUR T1 - Vitamin D Receptor Fok1 Polymorphism and Blood Lead Concentration in Children AN - 14671087; 10650977 JF - Environmental Health Perspectives AU - Haynes, Erin N AU - Kalkwarf, Heidi J AU - Hornung, Richard AU - Wenstrup, Richard AU - Dietrich, Kim AU - Lanphear, Bruce P Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1665 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - LEAD POISONING KW - BLOOD LEAD LEVEL KW - LEAD KW - RESPIRABLE DUST KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671087?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Vitamin+D+Receptor+Fok1+Polymorphism+and+Blood+Lead+Concentration+in+Children&rft.au=Haynes%2C+Erin+N%3BKalkwarf%2C+Heidi+J%3BHornung%2C+Richard%3BWenstrup%2C+Richard%3BDietrich%2C+Kim%3BLanphear%2C+Bruce+P&rft.aulast=Haynes&rft.aufirst=Erin&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1665&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - LEAD POISONING; BLOOD LEAD LEVEL; LEAD; RESPIRABLE DUST; GENETICS, HUMAN ER - TY - JOUR T1 - Comparable Measures of Cognitive Function in Human Infants and Laboratory Animals to Identify Environmental Health Risks to Children AN - 14671059; 10650972 AB - Results are summarized from a review of post-1990, peer-reviewed literature that has examined measures of cognitive function that can be applied to both human infants and laboratory animals. The tests included: eye-blink conditioning, visual habituation/novelty preference tasks and visual recognition memory tasks, A-not-B tasks and delay-tolerance A-not-B tasks, the transparent barrier detour task, mobile/train conjugate reinforcement tasks, delayed nonmatching-to-sample tasks, meansend problem-solving tasks, event-related potentials, operant discrimination learning, and Bayley scales of infant development. Several homologous tasks were found for humans and nonhuman primates, some of which were suitable for the study of infants, but only one homologous task, the classic eye-blink conditioning, could be used in humans, nonhuman primates, and rodents. JF - Environmental Health Perspectives AU - Sharbaugh, Carolyn AU - Viet, Susan Marie AU - Fraser, Alexa AU - McMaster, Suzanne B Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1630 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - NEUROTOXICITY KW - SPECIES COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671059?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Comparable+Measures+of+Cognitive+Function+in+Human+Infants+and+Laboratory+Animals+to+Identify+Environmental+Health+Risks+to+Children&rft.au=Sharbaugh%2C+Carolyn%3BViet%2C+Susan+Marie%3BFraser%2C+Alexa%3BMcMaster%2C+Suzanne+B&rft.aulast=Sharbaugh&rft.aufirst=Carolyn&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1630&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; NEUROTOXICITY; SPECIES COMPARISONS ER - TY - JOUR T1 - Measurement of Offline Exhaled Nitric Oxide in a Study of Community Exposure to Air Pollution AN - 14671049; 10650971 AB - Using 19 children aged 613 yr recruited from an asthma and allergy clinic in Seattle, WA, the association between daily changes in exhaled nitric oxide (eNO) and daily changes in fine particle levels was explored. The exhaled breath measurements were collected off-line daily in the children's homes into a NO-inert and impermeable Mylar balloon for up to ten consecutive days, and PM sub(2.5) measurements were taken inside and outside the subjects' residences. The average eNO concentrations for all subjects over 10 d were 19.9 ppb during the winter sessions and 12.7 ppb during the spring sessions, and associations were found between eNO levels and PM sub(2.5) levels. Significant interactions were also found between PM sub(2.5) concentrations and medication-use category. JF - Environmental Health Perspectives AU - Koenig, J Q AU - Jansen, K AU - Mar, T F AU - Lumley, T AU - Kaufman, J AU - Trenga, CA AU - Sullivan, J Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1625 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - WASHINGTON STATE KW - URBAN ATMOSPHERE KW - PARTICULATES KW - ASTHMA KW - NITRIC OXIDE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671049?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Measurement+of+Offline+Exhaled+Nitric+Oxide+in+a+Study+of+Community+Exposure+to+Air+Pollution&rft.au=Koenig%2C+J+Q%3BJansen%2C+K%3BMar%2C+T+F%3BLumley%2C+T%3BKaufman%2C+J%3BTrenga%2C+CA%3BSullivan%2C+J&rft.aulast=Koenig&rft.aufirst=J&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1625&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 27 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; WASHINGTON STATE; ASTHMA; NITRIC OXIDE; PARTICULATES; URBAN ATMOSPHERE ER - TY - JOUR T1 - Risk Management and Precaution: Insights on the Cautious Use of Evidence AN - 14671032; 10650963 AB - One must expect to have a large proportion of false positives for any single, practical screening procedure that is used to gain evidence for managing risks from important and well-characterized but rare hazards. Examples are provided of such cases to show that the conventional practices of risk management will encounter a dominance of false positives, even when they rely on valid screening evidence in the case of searching for rare hazards, as the screening method must be applied to an overwhelming proportion of nonhazards in search of a rare hazard. It is argued that, while poor risk management arises from an inadequate level of precaution, seeking an excessively high and ultimately self-defeating level of precaution for a narrowly defined rare hazard also provides poor risk management. Risk management must maintain a healthy tension based on considering the likelihood and consequences of both false-positive and -negative errors and seek an appropriate balance between the two. JF - Environmental Health Perspectives AU - Hrudey, Steve E AU - Leiss, William Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1577 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - DECISION MAKING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Risk+Management+and+Precaution%3A+Insights+on+the+Cautious+Use+of+Evidence&rft.au=Hrudey%2C+Steve+E%3BLeiss%2C+William&rft.aulast=Hrudey&rft.aufirst=Steve&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1577&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DECISION MAKING ER - TY - JOUR T1 - Exposure Assessment for Endocrine Disruptors: Some Considerations in the Design of Studies AN - 14670860; 10650980 AB - Various aspects of exposure assessment for studying the effects of endocrine disruptors are discussed. Considered in turn are the possible routes of exposure and the mechanisms of response; the importance of considering the timing, frequency, and duration of exposure; the need for qualitative and quantitative data; sample collection and storage for both short- and long-term studies; sample analysis; and exposure assessment in hypothesis testing and in hypothesis generation. JF - Environmental Health Perspectives AU - Rice, Carol AU - Birnbaum, Linda S AU - Cogliano, James AU - Mahaffey, Kathryn AU - Needham, Larry AU - Rogan, Walter J AU - vom Saal, Frederick S Y1 - 2003/10// PY - 2003 DA - Oct 2003 SP - 1683 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - HORMONAL EFFECTS KW - CHEMICAL CONTAMINATION KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14670860?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Exposure+Assessment+for+Endocrine+Disruptors%3A+Some+Considerations+in+the+Design+of+Studies&rft.au=Rice%2C+Carol%3BBirnbaum%2C+Linda+S%3BCogliano%2C+James%3BMahaffey%2C+Kathryn%3BNeedham%2C+Larry%3BRogan%2C+Walter+J%3Bvom+Saal%2C+Frederick+S&rft.aulast=Rice&rft.aufirst=Carol&rft.date=2003-10-01&rft.volume=111&rft.issue=13&rft.spage=1683&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; HORMONAL EFFECTS; CHEMICAL CONTAMINATION; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex. AN - 75748070; 14527430 AB - I(Ks) voltage-gated K(+) channels contain four pore-forming KCNQ1 subunits and MinK accessory subunits in a number that has been controversial. Here, I(Ks) channels assembled naturally by monomer subunits are compared to those with linked subunits that force defined stoichiometries. Two strategies that exploit charybdotoxin (CTX)-sensitive subunit variants are applied. First, CTX on rate, off rate, and equilibrium affinity are found to be the same for channels of monomers and those with a fixed 2:4 MinK:KCNQ1 valence. Second, 3H-CTX and an antibody are used to directly quantify channels and MinK subunits, respectively, showing 1.97 +/- 0.07 MinK per I(Ks) channel. Additional MinK subunits do not enter channels of monomeric subunits or those with fixed 2:4 valence. We conclude that two MinK subunits are necessary, sufficient, and the norm in I(Ks) channels. This stoichiometry is expected for other K(+) channels that contain MinK or MinK-related peptides (MiRPs). JF - Neuron AU - Chen, Haijun AU - Kim, Leo A AU - Rajan, Sindhu AU - Xu, Shuhua AU - Goldstein, Steve A N AD - Department of Pediatrics, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. Y1 - 2003/09/25/ PY - 2003 DA - 2003 Sep 25 SP - 15 EP - 23 VL - 40 IS - 1 SN - 0896-6273, 0896-6273 KW - Potassium Channels KW - 0 KW - Potassium Channels, Voltage-Gated KW - Protein Subunits KW - potassium channel protein I(sk) KW - Charybdotoxin KW - 115422-61-2 KW - Index Medicus KW - Animals KW - COS Cells KW - Dose-Response Relationship, Drug KW - Humans KW - Amino Acid Sequence KW - Protein Subunits -- metabolism KW - Protein Subunits -- chemistry KW - Protein Binding -- physiology KW - Protein Subunits -- genetics KW - Cercopithecus aethiops KW - Molecular Sequence Data KW - Xenopus KW - Sequence Homology, Amino Acid KW - Mutation KW - Female KW - Potassium Channels -- metabolism KW - Potassium Channels, Voltage-Gated -- antagonists & inhibitors KW - Potassium Channels -- chemistry KW - Potassium Channels, Voltage-Gated -- genetics KW - Potassium Channels -- genetics KW - Potassium Channels, Voltage-Gated -- chemistry KW - Potassium Channels, Voltage-Gated -- metabolism KW - Charybdotoxin -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/75748070?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neuron&rft.atitle=Charybdotoxin+binding+in+the+I%28Ks%29+pore+demonstrates+two+MinK+subunits+in+each+channel+complex.&rft.au=Chen%2C+Haijun%3BKim%2C+Leo+A%3BRajan%2C+Sindhu%3BXu%2C+Shuhua%3BGoldstein%2C+Steve+A+N&rft.aulast=Chen&rft.aufirst=Haijun&rft.date=2003-09-25&rft.volume=40&rft.issue=1&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Neuron&rft.issn=08966273&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-10-29 N1 - Date created - 2003-10-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Ds tagging of BRANCHED FLORETLESS 1 (BFL1) that mediates the transition from spikelet to floret meristem in rice (Oryza sativa L). AN - 71577783; 14503923 AB - The genetics of spikelet formation, a feature unique to grasses such as rice and maize, is yet to be fully understood, although a number of meristem and organ identity mutants have been isolated and investigated in Arabidopsis and maize. Using a two-element Ac/Ds transposon tagging system we have isolated a rice mutant, designated branched floretless 1 (bfl1) which is defective in the transition from spikelet meristem to floret meristem. The bfl1 mutant shows normal differentiation of the primary rachis-branches leading to initial spikelet meristem (bract-like structure equivalent to rudimentary glumes) formation but fails to develop empty glumes and florets. Instead, axillary meristems in the bract-like structure produce sequential alternate branching, thus resulting in a coral shaped morphology of the branches in the developing panicle. The bfl1 mutant harbours a single Ds insertion in the upstream region of the BFL1 gene on chromosome 7 corresponding to PAC clone P0625E02 (GenBank Acc No. message URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=nucleotide&list_uids=34395191&dopt=GenBank&term=ap004570AP004570). RT-PCR analyses revealed a drastic reduction of BFL1 transcript levels in the bfl1 mutant compared to that in the wild-type. In each of the normal panicle-bearing progeny plants, from occasional revertant seeds of the vegetatively-propagated mutant plant, Ds was shown to be excised from the bfl1 locus. BFL1 contains an EREBP/AP2 domain and is most likely an ortholog of the maize transcription factor gene BRANCHED SILKLESS1 (BD1). bfl1 is a Ds-tagged rice mutant defective in the transition from spikelet meristem (SM) to floret meristem (FM). BFL1 is most probably a rice ortholog of the maize ERF (EREBP/AP2) transcription factor gene BD1. Based on the similarities in mutant phenotypes bfl1 is likely to be an allele of the previously reported frizzy panicle locus. JF - BMC plant biology AU - Zhu, Qian-Hao AU - Hoque, Mohammad Shamsul AU - Dennis, Elizabeth S AU - Upadhyaya, Narayana M AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia. qianhao.zhu@csiro.au Y1 - 2003/09/23/ PY - 2003 DA - 2003 Sep 23 SP - 6 VL - 3 KW - DNA Transposable Elements KW - 0 KW - DNA, Plant KW - Plant Proteins KW - RNA, Plant KW - Transcription Factors KW - Index Medicus KW - Plant Proteins -- genetics KW - Amino Acid Sequence KW - Reverse Transcriptase Polymerase Chain Reaction KW - Transcription Factors -- genetics KW - Genome, Plant KW - Genotype KW - Phenotype KW - Base Sequence KW - DNA, Plant -- genetics KW - Blotting, Southern KW - RNA, Plant -- genetics KW - Binding Sites -- genetics KW - Gene Expression Regulation, Plant KW - Sequence Homology, Amino Acid KW - RNA, Plant -- metabolism KW - Mutagenesis, Insertional KW - Microscopy, Electron, Scanning KW - Flowers -- genetics KW - Meristem -- ultrastructure KW - Oryza -- growth & development KW - Flowers -- growth & development KW - Meristem -- growth & development KW - DNA Transposable Elements -- genetics KW - Flowers -- ultrastructure KW - Oryza -- genetics KW - Mutation KW - Meristem -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71577783?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+plant+biology&rft.atitle=Ds+tagging+of+BRANCHED+FLORETLESS+1+%28BFL1%29+that+mediates+the+transition+from+spikelet+to+floret+meristem+in+rice+%28Oryza+sativa+L%29.&rft.au=Zhu%2C+Qian-Hao%3BHoque%2C+Mohammad+Shamsul%3BDennis%2C+Elizabeth+S%3BUpadhyaya%2C+Narayana+M&rft.aulast=Zhu&rft.aufirst=Qian-Hao&rft.date=2003-09-23&rft.volume=3&rft.issue=&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=BMC+plant+biology&rft.issn=1471-2229&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-12 N1 - Date created - 2004-05-10 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Annu Rev Cell Dev Biol. 1999;15:519-50 [10611971] Plant J. 1999 Aug;19(4):489-95 [10504571] J Cell Sci. 2000 Oct;113 ( Pt 20):3547-8 [11017868] Trends Plant Sci. 2000 Feb;5(2):61-6 [10664615] Curr Opin Plant Biol. 2001 Feb;4(1):63-8 [11163170] Dev Biol. 2001 Mar 15;231(2):364-73 [11237465] Plant Physiol. 2001 Dec;127(4):1425-9 [11743085] Plant Cell. 2001 Dec;13(12):2609-18 [11752375] Trends Plant Sci. 2002 Jan;7(1):22-31; dicussion 31-4 [11804823] Plant J. 2002 Mar;29(6):743-50 [12148532] Science. 2002 Nov 8;298(5596):1238-41 [12424380] Nature. 2003 Apr 17;422(6933):719-22 [12700762] Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):387-95 [6546423] J Mol Biol. 1990 Oct 5;215(3):403-10 [2231712] Nature. 1991 Mar 21;350(6315):241-3 [1672445] Plant Mol Biol. 1992 Aug;19(5):881-5 [1386537] Plant Cell. 1995 Feb;7(2):173-82 [7756828] Plant Cell. 1995 Apr;7(4):388-9 [7773013] Plant J. 1995 Sep;8(3):457-63 [7550382] Nature. 1996 Feb 29;379(6568):791-7 [8587601] Plant Cell. 1996 Apr;8(4):659-71 [8624440] Mol Gen Genet. 1997 Mar 26;254(2):186-94 [9108281] Nucleic Acids Res. 1997 Sep 1;25(17):3389-402 [9254694] Development. 1997 Aug;124(16):3045-54 [9272946] Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):1979-82 [9482818] Genes Dev. 1998 Apr 15;12(8):1145-54 [9553044] Biol Chem. 1998 Jun;379(6):633-46 [9687012] Development. 2000 Nov;127(22):4971-80 [11044410] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Selection of continence products: perspectives of people who have incontinence and their carers. AN - 85373125; pmid-12851083 AB - The needs, issues and concerns of people with incontinence and their carers were explored in order to inform the development of a comprehensive Australian consumer guide to continence products.Semi-structured interviews and focus groups were conducted with a wide range of people with incontinence and carers. Questions centred around issues and concerns regarding continence product selection, what information people need to make informed choices, and how the information should be presented. Qualitative analysis highlighted common themes and specific issues.Issues raised by consumers included the paucity of written information currently available, ignorance among health professionals concerning continence products and the lack of information about sources of help. Most consumers selected products by trial and error and were unaware of the range of products and services available. They wanted a consumer guide to continence products to be user-friendly and easily accessible, with information on product availability, cost, quality, comfort and design. They also wanted more general information on incontinence, sources of help, and how to select, care for and dispose of products. Participants wanted the guide to be made available in different languages, in large print and simple language.The findings highlight the need and provide a framework for a consumer guide and information on continence products. JF - Disability and rehabilitation AU - Paterson, J AU - Dunn, S AU - Kowanko, I AU - van Loon, A AU - Stein, I AU - Pretty, L AD - School of Nursing and Midwifery, Flinders University, GPO Box 2100, Adelaide, Australia, 5001. Y1 - 2003/09/02/ PY - 2003 DA - 2003 Sep 02 SP - 955 EP - 963 VL - 25 IS - 17 SN - 0963-8288, 0963-8288 KW - Index Medicus KW - National Library of Medicine KW - Australia KW - Caregivers: psychology KW - Consumer Satisfaction KW - Decision Making KW - Equipment Reuse KW - Fecal Incontinence: psychology KW - Focus Groups: methods KW - Health Services Needs and Demand KW - Humans KW - *Incontinence Pads KW - Information Services KW - Research Design KW - Urinary Incontinence: psychology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85373125?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Disability+and+rehabilitation&rft.atitle=Selection+of+continence+products%3A+perspectives+of+people+who+have+incontinence+and+their+carers.&rft.au=Paterson%2C+J%3BDunn%2C+S%3BKowanko%2C+I%3Bvan+Loon%2C+A%3BStein%2C+I%3BPretty%2C+L&rft.aulast=Paterson&rft.aufirst=J&rft.date=2003-09-02&rft.volume=25&rft.issue=17&rft.spage=955&rft.isbn=&rft.btitle=&rft.title=Disability+and+rehabilitation&rft.issn=09638288&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - Inversion of axial coordination in myoglobin to create a "proximal" ligand binding pocket. AN - 73603723; 12939147 AB - A ligand binding pocket has been created on the proximal side of the heme in porcine myoglobin by site-directed mutagenesis. Our starting point was the H64V/V68H double mutant which has been shown to have bis-histidine (His68 and His93) heme coordination [Dou, Y., Admiraal, S. J., Ikeda-Saito, M., Krzywda, S., Wilkinson, A. J., Li, T., Olson, J. S., Prince, R. C., Pickering, I. J., George, G. N. (1995) J. Biol. Chem. 270, 15993-16001]. The replacement of the proximal His93 ligand by noncoordinating Ala (H64V/V68H/H93A) or Gly (H64V/V68H/H93G) residues resulted unexpectedly in a six-coordinate low-spin species in both ferric and ferrous states. To test the hypothesis that the sixth coordinating ligand in the triple mutants was the imidazole of His97, this residue was mutated to Phe, in the quadruple mutants, H64V/V68H/H93A/H97F and H64V/V68H/H93G/H97F. The ferric quadruple mutants show a clear water/hydroxide alkaline transition and high cyanide and CO affinities, characteristics similar to those of wild-type myoglobin. The nu(Fe-CO) and nu(C-O) stretching frequencies in the ferrous-CO state of the quadruple mutants indicate that the "proximal" ligand binding heme pocket is less polar than the distal pocket in the wild-type protein. Thus, we conclude that the proximal heme pocket in the quadruple mutants has a similar affinity for exogenous ligands to the distal pocket of wild-type myoglobin but that the two pockets have different polarities. The quadruple mutants open up new approaches for developing heme chemistry on the myoglobin scaffold. JF - Biochemistry AU - Uno, Tadayuki AU - Sakamoto, Rikiharu AU - Tomisugi, Yoshikazu AU - Ishikawa, Yoshinobu AU - Wilkinson, Anthony J AD - Graduate School of Pharmaceutical Sciences, Kumamoto University, Oehonmachi, Kumamoto 862-0973, Japan. unot@gpo.kumamoto-u.ac.jp Y1 - 2003/09/02/ PY - 2003 DA - 2003 Sep 02 SP - 10191 EP - 10199 VL - 42 IS - 34 SN - 0006-2960, 0006-2960 KW - Cyanides KW - 0 KW - Ferric Compounds KW - Ferrous Compounds KW - Ligands KW - Myoglobin KW - Recombinant Proteins KW - Heme KW - 42VZT0U6YR KW - Carbon Monoxide KW - 7U1EE4V452 KW - Index Medicus KW - Swine KW - Animals KW - Cyanides -- chemistry KW - Models, Molecular KW - Hydrogen-Ion Concentration KW - Ferric Compounds -- chemistry KW - Spectrum Analysis, Raman KW - Recombinant Proteins -- genetics KW - Protein Binding KW - Carbon Monoxide -- chemistry KW - Ferrous Compounds -- chemistry KW - Heme -- genetics KW - Spectrophotometry -- methods KW - Binding Sites KW - Recombinant Proteins -- metabolism KW - Cyanides -- metabolism KW - Kinetics KW - Heme -- chemistry KW - Recombinant Proteins -- chemistry KW - Carbon Monoxide -- metabolism KW - Amino Acid Substitution KW - Myoglobin -- genetics KW - Myoglobin -- chemistry KW - Myoglobin -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73603723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biochemistry&rft.atitle=Inversion+of+axial+coordination+in+myoglobin+to+create+a+%22proximal%22+ligand+binding+pocket.&rft.au=Uno%2C+Tadayuki%3BSakamoto%2C+Rikiharu%3BTomisugi%2C+Yoshikazu%3BIshikawa%2C+Yoshinobu%3BWilkinson%2C+Anthony+J&rft.aulast=Uno&rft.aufirst=Tadayuki&rft.date=2003-09-02&rft.volume=42&rft.issue=34&rft.spage=10191&rft.isbn=&rft.btitle=&rft.title=Biochemistry&rft.issn=00062960&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-10-07 N1 - Date created - 2003-08-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Electrochemical characterization of purified Rhus vernicifera laccase: voltammetric evidence for a sequential four-electron transfer. AN - 73573089; 12939151 AB - Rhus vernicifera (Rv) laccase was purified to electrophoretic homogeneity by hydrophobic interaction chromatography. A comprehensive study of the direct electrochemistry of Rv laccase covalently immobilized at a gold electrode using alkanethiol monolayers was undertaken. The observed midpoint potential was 410 mV versus the normal hydrogen electrode (NHE), consistent with reduction potentials obtained by potentiometric titration for the T1 copper site. Evidence is presented for a concerted 4-electron reversible process at slow scan rates (v) on the basis of peak current ratios (i(pa)/i(pc)). Catalytic currents were observed in the presence of the biological substrate oxygen, indicating that laccase activity is retained throughout the immobilization process. Electrochemical characteristics of the immobilized laccase were essentially invariant across the pH range 5.5-8.5 and the temperature range 5-35 degrees C. The purified enzyme displayed a pH optimum of 9.0, when assayed spectrophotometrically with syringaldazine as a substrate. Inhibition of the laccase activity with azide or fluoride showed an I(50)(NaN(3)) of 2.5 mM and an I(50)(NaF) of 18.5 mM. Electrochemistry in the presence of azide reduces the anodic current by ca. one-half, consistent with the 4-electron process decreasing to a 2-electron process. However, fluoride has no effect on anaerobic electrochemistry. These electrochemical results suggest that the pH dependence of laccase activity is related to the effects of pH on the structure or binding of the substrate. JF - Biochemistry AU - Johnson, Daniel L AU - Thompson, Janene L AU - Brinkmann, Sandra M AU - Schuller, Kathryn A AU - Martin, Lisandra L AD - School of Biological Sciences and Chemistry, Faculty of Science and Engineering, Flinders University, GPO Box 2100, Adelaide 5001, South Australia, Australia. Y1 - 2003/09/02/ PY - 2003 DA - 2003 Sep 02 SP - 10229 EP - 10237 VL - 42 IS - 34 SN - 0006-2960, 0006-2960 KW - Enzyme Inhibitors KW - 0 KW - Enzymes, Immobilized KW - Gold KW - 7440-57-5 KW - Sodium Fluoride KW - 8ZYQ1474W7 KW - Sodium Azide KW - 968JJ8C9DV KW - Oxidoreductases KW - EC 1.- KW - Laccase KW - EC 1.10.3.2 KW - Oxygen KW - S88TT14065 KW - Index Medicus KW - Electron Transport KW - Electrophoresis, Polyacrylamide Gel KW - Hydrogen-Ion Concentration KW - Oxygen -- metabolism KW - Temperature KW - Sodium Azide -- pharmacology KW - Electrochemistry -- methods KW - Enzyme Stability KW - Kinetics KW - Electrodes KW - Sodium Fluoride -- pharmacology KW - Enzyme Inhibitors -- pharmacology KW - Gold -- chemistry KW - Catalysis KW - Oxidoreductases -- isolation & purification KW - Oxidoreductases -- metabolism KW - Enzymes, Immobilized -- antagonists & inhibitors KW - Enzymes, Immobilized -- metabolism KW - Rhus -- enzymology KW - Oxidoreductases -- chemistry KW - Enzymes, Immobilized -- chemistry KW - Oxidoreductases -- antagonists & inhibitors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73573089?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biochemistry&rft.atitle=Electrochemical+characterization+of+purified+Rhus+vernicifera+laccase%3A+voltammetric+evidence+for+a+sequential+four-electron+transfer.&rft.au=Johnson%2C+Daniel+L%3BThompson%2C+Janene+L%3BBrinkmann%2C+Sandra+M%3BSchuller%2C+Kathryn+A%3BMartin%2C+Lisandra+L&rft.aulast=Johnson&rft.aufirst=Daniel&rft.date=2003-09-02&rft.volume=42&rft.issue=34&rft.spage=10229&rft.isbn=&rft.btitle=&rft.title=Biochemistry&rft.issn=00062960&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-10-07 N1 - Date created - 2003-08-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Evidence that store-operated Ca2+ channels are more effective than intracellular messenger-activated non-selective cation channels in refilling rat hepatocyte intracellular Ca2+ stores. AN - 73518035; 12887971 AB - Liver cells possess store-operated Ca2+ channels (SOCs) with a high selectivity for Ca2+ compared with Na+, and several types of intracellular messenger-activated non-selective cation channels with a lower selectivity for Ca2+ (NSCCs). The main role of SOCs is thought to be in refilling depleted endoplasmic reticulum Ca2+ stores [Cell Calcium 7 (1986) 1]. NSCCs may be involved in refilling intracellular stores but are also thought to have other roles in regulating the cytoplasmic-free Ca2+ and Na+ concentrations. The ability of SOCs to refill the endoplasmic reticulum Ca2+ stores in hepatocytes has not previously been compared with that of NSCCs. The aim of the present studies was to compare the ability of SOCs and maitotoxin-activated NSCCs to refill the endoplasmic reticulum in rat hepatocytes. The experiments were performed using fura-2FF and fura-2 to monitor the free Ca2+ concentrations in the endoplasmic reticulum and cytoplasmic space, respectively, a Ca2+ add-back protocol, and 2-aminoethyl diphenylborate (2-APB) to inhibit Ca2+ inflow through SOCs. In cells treated with 2,5-di-t-butylhydroquinone (DBHQ) or vasopressin to deplete the endoplasmic reticulum Ca2+ stores, then washed to remove DBHQ or vasopressin, the addition of Ca2+ caused a substantial increase in the concentration of Ca2+ in the endoplasmic reticulum and cytoplasmic space due to the activation of SOCs. These increases were inhibited 80% by 2-APB, indicating that Ca2+ inflow is predominantly through SOCs. In the presence of 2-APB (to block SOCs), maitotoxin induced a substantial increase in [Ca2+](cyt), but only a modest and slower increase in [Ca2+](er). Under these conditions, Ca2+ inflow is predominantly through maitotoxin-activated NSCCs. It is concluded that SOCs are more effective than maitotoxin-activated NSCCs in refilling the endoplasmic reticulum Ca2+ stores. The previously developed concept of a specific role for SOCs in refilling the endoplasmic reticulum is consistent with the results reported here. JF - Cell calcium AU - Gregory, R B AU - Sykiotis, D AU - Barritt, G J AD - Department of Medical Biochemistry, School of Medicine, Faculty of Health Sciences, Flinders University, G.P.O. Box 2100, South Australia 5001, Adelaide, Australia. Y1 - 2003/09// PY - 2003 DA - September 2003 SP - 241 EP - 251 VL - 34 IS - 3 SN - 0143-4160, 0143-4160 KW - Boron Compounds KW - 0 KW - Calcium Channel Agonists KW - Calcium Channel Blockers KW - Calcium Channels KW - Hydroquinones KW - Ion Channels KW - Marine Toxins KW - Oxocins KW - Vasopressins KW - 11000-17-2 KW - 2,5-di-tert-butylhydroquinone KW - 26XK13B61B KW - Thapsigargin KW - 67526-95-8 KW - Inositol 1,4,5-Trisphosphate KW - 85166-31-0 KW - maitotoxin KW - 9P59GES78D KW - Ca(2+) Mg(2+)-ATPase KW - EC 3.6.1.- KW - Calcium KW - SY7Q814VUP KW - Fura-2 KW - TSN3DL106G KW - Epinephrine KW - YKH834O4BH KW - Index Medicus KW - Marine Toxins -- pharmacology KW - Endoplasmic Reticulum -- metabolism KW - Animals KW - Cytoplasm -- drug effects KW - Calcium Channel Agonists -- pharmacology KW - Oxocins -- pharmacology KW - Inositol 1,4,5-Trisphosphate -- pharmacology KW - Thapsigargin -- pharmacology KW - Rats KW - Microscopy, Fluorescence KW - Hydroquinones -- pharmacology KW - Boron Compounds -- pharmacology KW - Calcium Channel Blockers -- pharmacology KW - Cytoplasm -- metabolism KW - Kinetics KW - Epinephrine -- pharmacology KW - Rats, Wistar KW - Vasopressins -- pharmacology KW - Fura-2 -- analogs & derivatives KW - Male KW - Ca(2+) Mg(2+)-ATPase -- metabolism KW - Endoplasmic Reticulum -- drug effects KW - Fura-2 -- metabolism KW - Calcium -- metabolism KW - Calcium Channels -- physiology KW - Ion Channels -- antagonists & inhibitors KW - Calcium -- analysis KW - Ion Channels -- physiology KW - Ion Channels -- agonists KW - Hepatocytes -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73518035?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cell+calcium&rft.atitle=Evidence+that+store-operated+Ca2%2B+channels+are+more+effective+than+intracellular+messenger-activated+non-selective+cation+channels+in+refilling+rat+hepatocyte+intracellular+Ca2%2B+stores.&rft.au=Gregory%2C+R+B%3BSykiotis%2C+D%3BBarritt%2C+G+J&rft.aulast=Gregory&rft.aufirst=R&rft.date=2003-09-01&rft.volume=34&rft.issue=3&rft.spage=241&rft.isbn=&rft.btitle=&rft.title=Cell+calcium&rft.issn=01434160&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-07 N1 - Date created - 2003-07-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Criminal Justice Policy Innovation in the States AN - 60707483; 200503395 AB - The early 1990s saw a flurry of activity in criminal justice legislation on both the state & federal levels. By January of 1993, pollsters found that crime had overtaken economic issues as the country's most important problem. During this time, four criminal justice policy innovations became popular with both state & federal officials: "Truth-in-Sentencing" laws, "Three-Strikes-You're-Out" laws, "boot camps" for convicted offenders, & juvenile court transfer provisions. This study attempts to determine what factors influenced states' adoptions of these innovations. It finds that states' crime rates were positively correlated with adoption of the measures, but other objective state factors, such as sentence length, were not. Strained state resources did not deter legislatures from enacting these policies. Voter ideology & political culture had less than expected impact. The study concludes that political entrepreneurs, rather than state characteristics, were responsible for adoption. 5 Tables, 40 References. [Reprinted by permission of Sage Publications Inc., copyright 2003.] JF - Criminal Justice Policy Review AU - Williams, Jackson AD - Public Citizen's Congress Watch Y1 - 2003/09// PY - 2003 DA - September 2003 SP - 401 EP - 422 VL - 14 IS - 3 SN - 0887-4034, 0887-4034 KW - United States of America KW - Policy Reform KW - Criminal Justice Policy KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60707483?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Criminal+Justice+Policy+Review&rft.atitle=Criminal+Justice+Policy+Innovation+in+the+States&rft.au=Williams%2C+Jackson&rft.aulast=Williams&rft.aufirst=Jackson&rft.date=2003-09-01&rft.volume=14&rft.issue=3&rft.spage=401&rft.isbn=&rft.btitle=&rft.title=Criminal+Justice+Policy+Review&rft.issn=08874034&rft_id=info:doi/10.1177%2F0887403403252456 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 40 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Criminal Justice Policy; Policy Reform; United States of America DO - http://dx.doi.org/10.1177/0887403403252456 ER - TY - JOUR T1 - Presidential Authority to Detain "Enemy Combatants" AN - 60702041; 200410507 AB - The Bush administration claims that the law of war & Supreme Court precedent support the president's authority to detain US citizens, incommunicado & without filing a criminal charge, as "enemy combatants." The administration views this power as inherent in the president's commander-in-chief authority, & that congressional authorization, while unnecessary, is implied in statute. This article surveys the history of presidential efforts to deal with threats to the national security through preventive detention measures, & concludes that congressional authorization has always been necessary to validate such measures within the US. 42 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Elsea, Jennifer K AD - Congressional Research Service, Library Congress Y1 - 2003/09// PY - 2003 DA - September 2003 SP - 568 EP - 601 VL - 33 IS - 3 SN - 0360-4918, 0360-4918 KW - Citizens KW - Presidents KW - Detention KW - Authority KW - Prisoners of War KW - United States of America KW - Civil Rights KW - Legislative Bodies KW - National Security KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60702041?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=Presidential+Authority+to+Detain+%22Enemy+Combatants%22&rft.au=Elsea%2C+Jennifer+K&rft.aulast=Elsea&rft.aufirst=Jennifer&rft.date=2003-09-01&rft.volume=33&rft.issue=3&rft.spage=568&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 42 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Detention; Prisoners of War; Civil Rights; Citizens; Presidents; National Security; Legislative Bodies; Authority; United States of America ER - TY - JOUR T1 - The Law: Walker v. Cheney: Legal Insulation of the Vice President from GAO Investigations AN - 60696637; 200410513 AB - In Walker v. Cheney, the District Court for the District of Columbia held that the General Accounting Office lacked standing to sue the vice president to compel the release of information pertaining to the administration's National Energy Policy Development Group. The court's decision brought an abrupt end to a highly publicized conflict between the executive & legislative branches, & legally insulated the Office of the Vice President from the GAO'S investigation. Despite the ramifications of the decision, the comptroller general did not pursue an appeal, leaving open significant questions regarding the scope of congressional oversight authority. 21 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Halstead, T J AD - Congressional Research Service, Library Congress Y1 - 2003/09// PY - 2003 DA - September 2003 SP - 635 EP - 648 VL - 33 IS - 3 SN - 0360-4918, 0360-4918 KW - Cheney, Dick KW - Vice Presidents KW - Investigations (Law Enforcement) KW - Freedom of Information KW - United States of America KW - Oversight KW - Judicial Decisions KW - Legislative Bodies KW - Energy Policy KW - Legal Cases KW - article KW - 9089: government/political systems; legislatures KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60696637?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=The+Law%3A+Walker+v.+Cheney%3A+Legal+Insulation+of+the+Vice+President+from+GAO+Investigations&rft.au=Halstead%2C+T+J&rft.aulast=Halstead&rft.aufirst=T&rft.date=2003-09-01&rft.volume=33&rft.issue=3&rft.spage=635&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 21 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Legal Cases; Energy Policy; Vice Presidents; Freedom of Information; Oversight; Investigations (Law Enforcement); Legislative Bodies; Judicial Decisions; United States of America ER - TY - JOUR T1 - Military Tribunals: A Sorry History AN - 60657201; 200410510 AB - After 9/11 (2001), President George W. Bush authorized the creation of military tribunals to try those who assisted in the terrorist attacks on New York City & Washington, DC. His military order closely tracked the model established by President Franklin D. Roosevelt, who appointed a military tribunal in 1942 to try eight German saboteurs. In Ex parte Quirin (1942), the Supreme Court unanimously upheld Roosevelt's tribunal. The Bush administration relies heavily on this judicial precedent, but military tribunals in US history have generally been hostile to civil liberties, procedural due process, & elementary standards of justice. 32 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Fisher, Louis AD - Congressional Research Service, Library Congress Y1 - 2003/09// PY - 2003 DA - September 2003 SP - 484 EP - 508 VL - 33 IS - 3 SN - 0360-4918, 0360-4918 KW - military tribunals KW - Due Process KW - United States of America KW - Civil Rights KW - War Crimes KW - Legal Procedure KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60657201?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=Military+Tribunals%3A+A+Sorry+History&rft.au=Fisher%2C+Louis&rft.aulast=Fisher&rft.aufirst=Louis&rft.date=2003-09-01&rft.volume=33&rft.issue=3&rft.spage=484&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 32 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - War Crimes; Legal Procedure; Due Process; Civil Rights; United States of America ER - TY - JOUR T1 - Organizing for Homeland Security AN - 60594156; 200410729 AB - For much of the 20th century, Congress & the president were rivals for determining the organization of the executive branch. The events of September 11, 2001, did not end that contest. The president sought to be the architect of new arrangements for protecting & maintaining homeland security, a nebulous term seeking to be a policy concept. Initial institutions created to exert leadership & coordination on behalf of the president were the Office of Homeland Security & the Homeland Security Council, simultaneously established by an executive order. Several months later, the president called for a new administrative organization, & steadfastly pursued the mandating of a Dept of Homeland Security, composed of existing entities of his choosing & vested with managerial flexibilities he considered to be essential. Ultimately, he largely obtained what he wanted in the legislation mandating the department. 36 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Relyea, Harold C AD - Congressional Research Service, Library Congress Y1 - 2003/09// PY - 2003 DA - September 2003 SP - 602 EP - 624 VL - 33 IS - 3 SN - 0360-4918, 0360-4918 KW - Presidents KW - Government Agencies KW - United States of America KW - Organizational Structure KW - Organizational Change KW - National Security KW - article KW - 9263: public policy/administration; public administration/bureaucracy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60594156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=Organizing+for+Homeland+Security&rft.au=Relyea%2C+Harold+C&rft.aulast=Relyea&rft.aufirst=Harold&rft.date=2003-09-01&rft.volume=33&rft.issue=3&rft.spage=602&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 36 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - National Security; Presidents; Government Agencies; Organizational Change; Organizational Structure; United States of America ER - TY - JOUR T1 - Poster Sessions 292 - 465 AN - 216197972 JF - Intensive Care Medicine Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - S79 EP - S122 CY - Heidelberg PB - Springer Science & Business Media VL - 29 SN - 03424642 KW - Medical Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/216197972?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthcompleteshell&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Intensive+Care+Medicine&rft.atitle=Poster+Sessions+292+-+465&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2003-09-01&rft.volume=29&rft.issue=&rft.spage=S79&rft.isbn=&rft.btitle=&rft.title=Intensive+Care+Medicine&rft.issn=03424642&rft_id=info:doi/10.1007%2Fs00134-003-1973-y LA - English DB - ProQuest Central N1 - Copyright - Copyright Springer-Verlag 2003 N1 - Last updated - 2014-08-02 DO - http://dx.doi.org/10.1007/s00134-003-1973-y ER - TY - JOUR T1 - Poster Sessions 054 - 231 AN - 216197859 JF - Intensive Care Medicine Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - S19 EP - S63 CY - Heidelberg PB - Springer Science & Business Media VL - 29 SN - 03424642 KW - Medical Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/216197859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthcompleteshell&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Intensive+Care+Medicine&rft.atitle=Poster+Sessions+054+-+231&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2003-09-01&rft.volume=29&rft.issue=&rft.spage=S19&rft.isbn=&rft.btitle=&rft.title=Intensive+Care+Medicine&rft.issn=03424642&rft_id=info:doi/10.1007%2Fs00134-003-1971-0 LA - English DB - ProQuest Central N1 - Copyright - Copyright Springer-Verlag 2003 N1 - Last updated - 2014-08-02 DO - http://dx.doi.org/10.1007/s00134-003-1971-0 ER - TY - JOUR T1 - Oral Presentations 466 - 554 AN - 216187113 JF - Intensive Care Medicine Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - S123 EP - S145 CY - Heidelberg PB - Springer Science & Business Media VL - 29 SN - 03424642 KW - Medical Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/216187113?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthcompleteshell&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Intensive+Care+Medicine&rft.atitle=Oral+Presentations+466+-+554&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2003-09-01&rft.volume=29&rft.issue=&rft.spage=S123&rft.isbn=&rft.btitle=&rft.title=Intensive+Care+Medicine&rft.issn=03424642&rft_id=info:doi/10.1007%2Fs00134-003-1974-x LA - English DB - ProQuest Central N1 - Copyright - Copyright Springer-Verlag 2003 N1 - Last updated - 2014-08-02 DO - http://dx.doi.org/10.1007/s00134-003-1974-x ER - TY - BOOK T1 - Groundwater-surface water interaction in inland New South Wales: A scoping study AN - 19402177; 5829744 AB - Groundwater and surface water have traditionally been managed separately in New South Wales (NSW). However, where rivers and aquifers are hydraulically connected, groundwater pumping has the potential to deplete streamflow. To highlight the major areas of connection in inland NSW, major streams were overlaid with groundwater depth data and the locations of irrigation bores. A consistent pattern was revealed related to basin geomorphology. The main areas of connection are the mid-sections of the major rivers where alluvial systems are well developed yet still narrow and constricted and groundwater depths are shallow. The mapping was validated and the processes explored by calculating water balances for a connected and disconnected reach in the Murrumbidgee River. These showed that, in highly connected reaches, river losses and/or gains are closely related to groundwater levels. JF - Water Science & Technology AU - Braaten, R AU - Gates, G A2 - Greenfield, P A2 - Ward, S (eds) Y1 - 2003/09// PY - 2003 DA - September 2003 SP - 10 EP - 224 PB - IWA Publishing, Alliance House 12 Caxton Street London SW1H 0QS UK SN - 1843394529 KW - Australia, New South Wales KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Aqualine Abstracts; Water Resources Abstracts KW - Water Management KW - Hydrologic Budget KW - Freshwater KW - Groundwater Level KW - Geomorphology KW - Ground water KW - Mapping KW - Pumping KW - Data Interpretation KW - Data Collections KW - Catchment Areas KW - Irrigation KW - Maps and mapping KW - Streamflow KW - Water Table KW - Stream flow KW - Water balance KW - Surface-groundwater Relations KW - Water management KW - AQ 00001:Water Resources and Supplies KW - SW 0810:General KW - Q2 09171:Dynamics of lakes and rivers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19402177?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Aqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Braaten%2C+R%3BGates%2C+G&rft.aulast=Braaten&rft.aufirst=R&rft.date=2003-09-01&rft.volume=&rft.issue=&rft.spage=215&rft.isbn=1843394529&rft.btitle=Groundwater-surface+water+interaction+in+inland+New+South+Wales%3A+A+scoping+study&rft.title=Groundwater-surface+water+interaction+in+inland+New+South+Wales%3A+A+scoping+study&rft.issn=02731223&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-01-01 N1 - Last updated - 2016-05-27 ER - TY - JOUR T1 - Evolutionary correlations between escape behaviour and performance ability in eight species of snow skinks (Niveoscincus: Lygosominae) from Tasmania AN - 18883187; 5725214 AB - Three locomotor modes were examined (sprinting, jumping and climbing) in eight species of skinks: seven Niveoscincus spp. and Pseudemoia entrecasteauxii. These species formed four distinct ecological types: ground-dwelling, arboreal, heath/rock dwelling, and saxicolous. Significant behavioural preferences for particular escape modes in the field were found, which reflected the performance capabilities at an animal in the laboratory. This study used both non-phylogenetic and evolutionary based analyses to demonstrate that species occupying different microhabitats and using different escape tactics exhibit corresponding differences in performance abilities. Four Niveoscincus species are specialized in performance abilities and behavioural responses (N. greeni, N. ocellatus, N. pretiosus, N. orocryptus) by excelling in some performance abilities but having behavioural restrictions at attemping other locomotor modes. Only N. microlepidotus and N. orocryptus used escape tactics opportunistically; these species possess a suite of behavioural responses that may reflect the wide range of microhabitats they occupy. Ground-dwelling species N. metallicus, N. coventryi and Pseudemoia entrecasteauxii performed poorly at all performance abilities and seemed to have biomechanical limitations, rather than behavioural restrictions, on locomotor mode. Thus, when making interspecific comparisons, the behaviour of an animal needs to be considered before appropriate performance measures are selected. Phylogenetic analyses demonstrate that escape tactics and performance abilities have co-evolved in Niveoscincus, with an evolutionary trend towards behavioural and locomotor specialization. JF - Journal of Zoology AU - Melville, J AU - Swain, R AD - Department of Sciences, Museum Victoria, G.P.O. Box 666E, Melbourne, VIC 3001, Australia, jmelv@museum.vic.gov.au Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 79 EP - 89 PB - Cambridge University Press, Journals, Journals Department 110 Midland Ave. Port Chester NY 10573-4930 USA, [mailto:ssoule@cup.org], [URL:http://www.cup.org] VL - 261 IS - 1 SN - 0952-8369, 0952-8369 KW - Ecology Abstracts; Animal Behavior Abstracts KW - D 04670:Reptiles KW - Y 25524:Vertebrates (excluding fish, birds & mammals) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18883187?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Zoology&rft.atitle=Evolutionary+correlations+between+escape+behaviour+and+performance+ability+in+eight+species+of+snow+skinks+%28Niveoscincus%3A+Lygosominae%29+from+Tasmania&rft.au=Melville%2C+J%3BSwain%2C+R&rft.aulast=Melville&rft.aufirst=J&rft.date=2003-09-01&rft.volume=261&rft.issue=1&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Journal+of+Zoology&rft.issn=09528369&rft_id=info:doi/10.1017%2FS0952836903003984 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1017/S0952836903003984 ER - TY - JOUR T1 - GenomeComp: a visualization tool for microbial genome comparison AN - 18855653; 5682818 AB - We have developed a software tool, GenomeComp, for summarizing, parsing and visualizing the genome sequences comparison results derived from voluminous BLAST textual output. With GenomeComp, the variation between genomes can be easily highlighted, such as repeat regions, insertions, deletions and rearrangements of genomic segments. This software provides a new visualizing tool for microbe comparative genomics. JF - Journal of Microbiological Methods AU - Yang, J AU - Wang, J AU - Yao, Z AU - Jin, Q AU - Shen, Y AU - Chen, R AD - Laboratory of Bioinformatics, Institute of Biophysics, CAS, Datun Road 15, Chaoyang District, Beijing 100101, PR China, crs@sun5.ibp.ac.cn Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 423 EP - 426 PB - Elsevier Science B.V. VL - 54 IS - 3 SN - 0167-7012, 0167-7012 KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Bioengineering Abstracts; Microbiology Abstracts B: Bacteriology KW - W2 32080:Bioinformatics and computer applications KW - W 30965:Miscellaneous, Reviews KW - W4 350:Bioinformatics KW - J 02740:Genetics and evolution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18855653?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=GenomeComp%3A+a+visualization+tool+for+microbial+genome+comparison&rft.au=Yang%2C+J%3BWang%2C+J%3BYao%2C+Z%3BJin%2C+Q%3BShen%2C+Y%3BChen%2C+R&rft.aulast=Yang&rft.aufirst=J&rft.date=2003-09-01&rft.volume=54&rft.issue=3&rft.spage=423&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2FS0167-7012%2803%2900094-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0167-7012(03)00094-0 ER - TY - JOUR T1 - Assessing the driving performance of older adult drivers: on-road versus simulated driving AN - 18798271; 5663504 AB - To validate a laboratory-based driving simulator in measuring on-road driving performance, 129 older adult drivers were assessed with both the simulator and an on-road test. The driving performance of the participants was gauged by appropriate and reliable age-specific assessment criteria, which were found to be negatively correlated with age. Using principal component analysis, two performance indices were developed from the criteria to represent the overall performance in simulated driving and the on-road assessment. There was significant positive association between the two indices, with the simulated driving performance index explaining over two-thirds of the variability of the on-road driving performance index, after adjustment for age and gender of the drivers. The results supported the validity of the driving simulator and it is a safer and more economical method than the on-road testing to assess the driving performance of older adult drivers. JF - Accident Analysis & Prevention AU - Lee, H C AU - Cameron, D AU - Lee, AH AD - School of Occupational Therapy, Driving Assessment and Consultancy Centre, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia, hoe.lee@health.wa.gov.au Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 797 EP - 803 VL - 35 IS - 5 SN - 0001-4575, 0001-4575 KW - driving ability KW - elderly KW - traffic safety KW - Health & Safety Science Abstracts; Risk Abstracts KW - R2 23020:Technological risks KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18798271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Accident+Analysis+%26+Prevention&rft.atitle=Assessing+the+driving+performance+of+older+adult+drivers%3A+on-road+versus+simulated+driving&rft.au=Lee%2C+H+C%3BCameron%2C+D%3BLee%2C+AH&rft.aulast=Lee&rft.aufirst=H&rft.date=2003-09-01&rft.volume=35&rft.issue=5&rft.spage=797&rft.isbn=&rft.btitle=&rft.title=Accident+Analysis+%26+Prevention&rft.issn=00014575&rft_id=info:doi/10.1016%2FS0001-4575%2802%2900083-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0001-4575(02)00083-0 ER - TY - JOUR T1 - A disaggregate approach to crash rate analysis AN - 18798064; 5663493 AB - This paper presents a disaggregate approach to crash rate analysis. Enumerating crash rates on a per trip-kilometer basis, the proposed method removes the linearity assumption inherent in the conventional quotient indicator of accidents per unit travel distance. The approach involves combining two disparate datasets on a geographic information systems (GIS) platform by matching accident records to a defined travel corridor. As an illustration of the methodology, travel information from the Victorian Activity and Travel Survey (VATS) and accident records contained in CrashStat were used to estimate the crash rates of Melbourne residents in different age-sex groups according to time of the day and day of the week. The results show a polynomial function of a cubic order when crash rates are plotted against age group, which contrasts distinctly with the U-shape curve generated by using the conventional aggregate quotient approach. Owing to the validity of the many assumptions adopted in the computation, this study does not claim that the results obtained are conclusive. The methodology, however, is seen as providing a framework upon which future crash risk measures could be based as the use of spatial tracking devises become prevalent in travel surveys. JF - Accident Analysis & Prevention AU - Kam, B H AD - School of Marketing, Royal Melbourne Institute of Technology, G.P.O. Box 2476v, Melbourne, Vic. 3000, Australia, b.kam@rmit.edu.au Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 693 EP - 709 VL - 35 IS - 5 SN - 0001-4575, 0001-4575 KW - traffic safety KW - Health & Safety Science Abstracts KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18798064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Accident+Analysis+%26+Prevention&rft.atitle=A+disaggregate+approach+to+crash+rate+analysis&rft.au=Kam%2C+B+H&rft.aulast=Kam&rft.aufirst=B&rft.date=2003-09-01&rft.volume=35&rft.issue=5&rft.spage=693&rft.isbn=&rft.btitle=&rft.title=Accident+Analysis+%26+Prevention&rft.issn=00014575&rft_id=info:doi/10.1016%2FS0001-4575%2802%2900048-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0001-4575(02)00048-9 ER - TY - JOUR T1 - Reciprocal control of flowering time by OsSOC1 in transgenic Arabidopsis and by FLC in transgenic rice AN - 17553320; 6422842 AB - In a screen for MADS box genes which activate and/or repress flowering in rice, we identified a gene encoding a MADS domain protein (OsSOC1) related to the Arabidopsis gene AtSOC1. AtSOC1 and OsSOC1 show a 97% amino acid similarity in their MADS domain. The rice gene contains a large first intron of 27.6 kb compared to the 1 kb intron in Arabidopsis. OsSOC1 is located on top of the short arm of chromosome 3, tightly linked to the heading date locus, Hd9. OsSOC1 is expressed in vegetative tissues, and expression is elevated at the time of floral initiation, 40-50 days after sowing, and remains uniformly high thereafter, similar to the expression pattern of AtSOC1. The constitutive expression of OsSOC1 in Arabidopsis results in early flowering, suggesting that the rice gene is a functional equivalent of AtSOC1. We were not able to identify FLC-like sequences in the rice genome; however, we show that ectopic expression of the Arabidopsis FLC delays flowering in rice, and the up-regulation of OsSOC1 at the onset of flowering initiation is delayed in the AtFLC transgenic lines. The reciprocal recognition and flowering time effects of genes introduced into either Arabidopsis or rice suggest that some components of the flowering pathways may be shared. This points to a potential application in the manipulation of flowering time in cereals using well characterized Arabidopsis genes. JF - Plant Biotechnology Journal AU - Tadege, M AU - Sheldon, C C AU - Helliwell, CA AU - Upadhyaya, N M AU - Dennis, E S AU - Peacock, W J AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, jim.peacock@csiro.au Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 361 EP - 369 VL - 1 IS - 5 SN - 1467-7644, 1467-7644 KW - Rice KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - Genomes KW - Flowering KW - Amino acids KW - Oryza sativa KW - chromosome 3 KW - MADS domain protein KW - Introns KW - Arabidopsis KW - W2 32065:Plants KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17553320?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Biotechnology+Journal&rft.atitle=Reciprocal+control+of+flowering+time+by+OsSOC1+in+transgenic+Arabidopsis+and+by+FLC+in+transgenic+rice&rft.au=Tadege%2C+M%3BSheldon%2C+C+C%3BHelliwell%2C+CA%3BUpadhyaya%2C+N+M%3BDennis%2C+E+S%3BPeacock%2C+W+J&rft.aulast=Tadege&rft.aufirst=M&rft.date=2003-09-01&rft.volume=1&rft.issue=5&rft.spage=361&rft.isbn=&rft.btitle=&rft.title=Plant+Biotechnology+Journal&rft.issn=14677644&rft_id=info:doi/10.1046%2Fj.1467-7652.2003.00034.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Arabidopsis; Oryza sativa; Flowering; Introns; Genomes; Amino acids; chromosome 3; MADS domain protein DO - http://dx.doi.org/10.1046/j.1467-7652.2003.00034.x ER - TY - JOUR T1 - Perceived Treatment Efficacy for Conventional and Alternative Therapies Reported by Persons with Multiple Chemical Sensitivity AN - 14675090; 10649964 JF - Environmental Health Perspectives AU - Gibson, Pamela Reed AU - Elms, Amy Nicole-Marie AU - Ruding, Lisa Ann Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1498 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHEMICAL CONTAMINATION, MULTIPLE KW - SENSITIVITY KW - MITIGATIVE MEASURES KW - DISEASES AND DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14675090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Perceived+Treatment+Efficacy+for+Conventional+and+Alternative+Therapies+Reported+by+Persons+with+Multiple+Chemical+Sensitivity&rft.au=Gibson%2C+Pamela+Reed%3BElms%2C+Amy+Nicole-Marie%3BRuding%2C+Lisa+Ann&rft.aulast=Gibson&rft.aufirst=Pamela&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1498&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL CONTAMINATION, MULTIPLE; MITIGATIVE MEASURES; SENSITIVITY; DISEASES AND DISORDERS ER - TY - JOUR T1 - Semen Quality in Relation to Biomarkers of Pesticide Exposure AN - 14675038; 10649961 AB - Subjects who were participants in the Study for Future Families, a multicenter study of semen quality in fertile men, were used to investigate the relationship between environmental pesticide exposure and semen quality. Fifteen nonpersistent pesticide metabolites were selected, which included metabolites of alachlor, atrazine, metolachlor, acetachlor, 2,4-D, 2,4,5-T, carbofuran, diazinon, carbaryl, chlorpyrifos, malathion, propoxur, methyl parathion, permethrin, and N,N-diethyl-m-toluamide. The study subjects lived in either Columbia, MO, or Minneapolis, MN. No significant associations were noted for any pesticides within Minnesota, where levels of agricultural pesticides were low, whereas poor semen quality in the Missouri subjects was associated with pesticide metabolite levels, especially alachlor, atrazine, diazinon, 2,4-D, and metolachlor. JF - Environmental Health Perspectives AU - Swan, Shanna H AU - Kruse, Robin L AU - Liu, Fan AU - Barr, Dana B AU - Drobnis, Erma Z AU - Redmon, JBruce AU - Wang, Christina Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1478 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SPERM KW - SEMEN KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14675038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Semen+Quality+in+Relation+to+Biomarkers+of+Pesticide+Exposure&rft.au=Swan%2C+Shanna+H%3BKruse%2C+Robin+L%3BLiu%2C+Fan%3BBarr%2C+Dana+B%3BDrobnis%2C+Erma+Z%3BRedmon%2C+JBruce%3BWang%2C+Christina&rft.aulast=Swan&rft.aufirst=Shanna&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1478&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SPERM; SEMEN; PESTICIDE EXPOSURE ER - TY - JOUR T1 - The Intact Immature Rodent Uterotrophic Bioassay: Possible Effects on Assay Sensitivity of Vomeronasal Signals from Male Rodents and Strain Differences AN - 14673467; 10649972 AB - Sexual development and maturity can be modulated by vomeronasal signals in rodents, and such development can also vary among different strains. Results are presented from a study of the possible effects of vomeronasal signals and strain differences on the performance of the rodent uterotrophic assay aimed at detecting weak estrogen agonists and antagonists. Mature male rats and mice were housed in close proximity to immature females, and the effects on uterine weight were determined after 3 d. Standard uterotrophic assays were also used to examine the sensitivity of four strains of immature mice to diethylstilbestrol. Results revealed that both the group mean of blotted and dry uterine weights and the standard deviations of the group means were unaffected by the proximity of males. All mice strains showed a highly significant uterotrophic response to diethylstilbestrol at 10 mu g/kg/d, but the uterine weight increase varied among strains. JF - Environmental Health Perspectives AU - Ashby, John AU - Owens, William AU - Odum, Jenny AU - Tinwell, Helen Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1568 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - HORMONAL EFFECTS KW - BIOASSAY KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673467?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Intact+Immature+Rodent+Uterotrophic+Bioassay%3A+Possible+Effects+on+Assay+Sensitivity+of+Vomeronasal+Signals+from+Male+Rodents+and+Strain+Differences&rft.au=Ashby%2C+John%3BOwens%2C+William%3BOdum%2C+Jenny%3BTinwell%2C+Helen&rft.aulast=Ashby&rft.aufirst=John&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1568&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; HORMONAL EFFECTS; BIOASSAY; RODENTS ER - TY - JOUR T1 - Significant Issues Raised by Metal-Analyses of Cancer Mortality and Dioxin Exposure AN - 14673451; 10649955 AB - Recent meta-analyses of cancer mortality and dioxin exposure have produced divergent results using similar analyses of essentially the same data. Several reasons are postulated for this discrepancy and are expanded upon. These include: a failure to allow for causes of elevated cancer mortality other than dioxin exposure, differences in choices for a dose metric, selective use of different assumptions regarding the elimination half-life of TCDD in humans, and selective use of different assumptions regarding the impact on cancer mortality of the most recent 15 yr of exposure. JF - Environmental Health Perspectives AU - Starr, Thomas B Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1443 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - TETRACHLORODIBENZODIOXINS KW - DOSE RESPONSE PROFILES KW - CARCINOGENIC AGENTS KW - MORTALITY PATTERNS KW - MATHEMATIC MODELS, CARCINOGENESIS KW - DIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Significant+Issues+Raised+by+Metal-Analyses+of+Cancer+Mortality+and+Dioxin+Exposure&rft.au=Starr%2C+Thomas+B&rft.aulast=Starr&rft.aufirst=Thomas&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1443&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 28 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; CARCINOGENIC AGENTS; MORTALITY PATTERNS; MATHEMATIC MODELS, CARCINOGENESIS; DIOXINS; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - An Assessment of the Cord Blood:Maternal Blood Methylmercury Ratio: Implications for Risk Assessment AN - 14673431; 10649959 JF - Environmental Health Perspectives AU - Stern, Alan H AU - Smith, Andrew E Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1465 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - METHYLMERCURY KW - REPRODUCTION, HUMAN KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673431?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=An+Assessment+of+the+Cord+Blood%3AMaternal+Blood+Methylmercury+Ratio%3A+Implications+for+Risk+Assessment&rft.au=Stern%2C+Alan+H%3BSmith%2C+Andrew+E&rft.aulast=Stern&rft.aufirst=Alan&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1465&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; METHYLMERCURY; REPRODUCTION, HUMAN; MERCURY ER - TY - JOUR T1 - Mosquito Coil Emissions and Health Implications AN - 14673394; 10649957 AB - Six brands of mosquito coils used commonly in China and Malaysia were compared in terms of emission rates of a variety of pollutants of health concern. Pollutants were measured in both the particulate phase and the gas phase of the coil smoke, and the particle size distribution of the smoke was determined. Using the determined emission rates and typical room parameters, room concentrations were predicted and compared with reference risk values. Results from the small chamber study showed that the highest normalized concentration fell in the size range 0.20.3 mu m, but in the room study, a bimodal size distribution curve was observed, with peaks at both 0.010.1 and 0.20.3 mu m. High concentrations of PAHs were measured in the particulate phase, some of which were suspected human carcinogens. In addition, several VOCs were identified, including benzene, toluene, ethylbenzene, styrene, and p-, m-, and o-xylene at relatively high concentrations. The pollutant emissions from the two tested Malaysian brands were substantially higher than those from the four tested Chinese brands. Compared with indoor pollutant concentrations from biomass fuel combustion, exposure to mosquito coil smoke was estimated to pose comparable or higher respiratory health risks with chronic use. JF - Environmental Health Perspectives AU - Liu, Weili AU - Zhang, Junfeng AU - Hashim, Jamal H AU - Jalaludin, Juliana AU - Hashim, Zailina AU - Goldstein, Bernard D Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1454 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - COMBUSTION KW - SMOKE KW - MOSQUITOES KW - MALAYSIA KW - POLYCYCLIC AROMATIC HYDROCARBON KW - INSECTICIDE USAGE KW - CHINA, PEOPLES' REPUBLIC KW - ALDEHYDES KW - VOLATILE ORGANIC COMPOUNDS KW - PARTICULATES KW - RISK ASSESSMENT KW - AIR POLLUTION, INDOOR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673394?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Mosquito+Coil+Emissions+and+Health+Implications&rft.au=Liu%2C+Weili%3BZhang%2C+Junfeng%3BHashim%2C+Jamal+H%3BJalaludin%2C+Juliana%3BHashim%2C+Zailina%3BGoldstein%2C+Bernard+D&rft.aulast=Liu&rft.aufirst=Weili&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1454&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; COMBUSTION; INSECTICIDE USAGE; SMOKE; AIR POLLUTION, INDOOR; MOSQUITOES; CHINA, PEOPLES' REPUBLIC; MALAYSIA; VOLATILE ORGANIC COMPOUNDS; PARTICULATES; ALDEHYDES; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - The OECD Program to Validate the Rat Uterotrophic Bioassay. Phase 2: Dietary Phytoestrogen Analyses AN - 14673252; 10649971 AB - Twenty laboratories participated in the OECD phase 2 validation studies of the rat uterotrophic bioassay aimed at screening suspected estrogen receptor agonists or antagonists. Results are presented from a comparison among the laboratories of the effects of dietary phytoestrogen exposure. Both the intact, immature and the adult ovariectomized versions of the bioassay were utilized. The laboratory diets were submitted for phytoestrogen analyses, and the response of the bioassay involving bisphenol A and nonylphenol in the diets was examined. No effect was evident on the responsiveness of the ovariectomized female to weak estrogen agonists, but the data suggested an effect for the immature rat model when genistein intakes exceeded 50 mg/kg/d. The higher food consumption rates of the immature animals relative to their body weights appeared central to the possible difference between the intact, immature and the adult ovariectomized versions of the protocol. JF - Environmental Health Perspectives AU - Owens, William AU - Ashby, John AU - Odum, Jenny AU - Onyon, Lesley Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1559 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HORMONAL EFFECTS KW - BIOASSAY KW - ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT KW - DIET KW - RATS KW - MEASUREMENTS AND SENSING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673252?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+OECD+Program+to+Validate+the+Rat+Uterotrophic+Bioassay.+Phase+2%3A+Dietary+Phytoestrogen+Analyses&rft.au=Owens%2C+William%3BAshby%2C+John%3BOdum%2C+Jenny%3BOnyon%2C+Lesley&rft.aulast=Owens&rft.aufirst=William&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1559&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 11 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; HORMONAL EFFECTS; BIOASSAY; DIET; ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT; RATS ER - TY - JOUR T1 - The OECD Program to Validate the Rat Uterotrophic Bioassay: an Overview AN - 14673235; 10649968 AB - Beginning in 1998, OECD developed new and revised guidelines for the screening and testing of potential endocrine disrupters, focusing in part on a validation of the rodent uterotrophic bioassay. The organization of the validation program is outlined. A detailed background review document was produced, which indicated that the uterotrophic bioassay is mechanistically relevant and is predictive in practice. Results are summarized from the phase 2 validation studies, which demonstrated that the uterotrophic bioassay protocols are robust and reliable for identifying estrogen agonists and antagonists and are transferable across laboratories. JF - Environmental Health Perspectives AU - Owens, William AU - Koeter, Herman BWM Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1527 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - HORMONAL EFFECTS KW - BIOASSAY KW - ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT KW - RATS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673235?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+OECD+Program+to+Validate+the+Rat+Uterotrophic+Bioassay%3A+an+Overview&rft.au=Owens%2C+William%3BKoeter%2C+Herman+BWM&rft.aulast=Owens&rft.aufirst=William&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1527&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t drawings N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; HORMONAL EFFECTS; BIOASSAY; ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT; RATS ER - TY - JOUR T1 - Neuroendocrine Effects of Perfluorooctane Sulfonate in Rats AN - 14673183; 10649962 AB - Using adult female SpragueDawley rats, the effect of perfluorooctane sulfonate (PFOS) on two axes of the neuroendocrine system, the reproductive axis and the stress axis, was studied. The accumulation of PFOS in several body tissues was measured, and the effects of PFOS on neurotransmitters and the hormones that they regulate were investigated. Results showed that, while liver was the target organ of accumulation, PFOS was found in other tissues, including the blood, serum, kidney, heart, ovaries, adrenal, brain, and spleen. Exposure to the compound produced marked changes in body weight and food intake, and decreases in food intake and body weight were followed by a significant reduction in serum leptin levels. After high-dose exposures, there was a significant increase in corticosterone and norepinephrine concentrations in the paraventricular nucleus, indicating a stimulatory effect on the stress axis. Exposure to PFOS also altered estrous cycling significantly. JF - Environmental Health Perspectives AU - Austin, Maureen E AU - Kasturi, Badrinarayanan S AU - Barber, Matthew AU - Kannan, Kurunthachalam AU - MohanKumar, Puliyur S AU - MohanKumar, Sheba MJ Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1485 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - FLUORINATED HYDROCARBONS KW - BIOACCUMULATION, ANIMAL KW - DOSE RESPONSE PROFILES KW - HORMONAL EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673183?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Neuroendocrine+Effects+of+Perfluorooctane+Sulfonate+in+Rats&rft.au=Austin%2C+Maureen+E%3BKasturi%2C+Badrinarayanan+S%3BBarber%2C+Matthew%3BKannan%2C+Kurunthachalam%3BMohanKumar%2C+Puliyur+S%3BMohanKumar%2C+Sheba+MJ&rft.aulast=Austin&rft.aufirst=Maureen&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1485&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOACCUMULATION, ANIMAL; FLUORINATED HYDROCARBONS; DOSE RESPONSE PROFILES; HORMONAL EFFECTS ER - TY - JOUR T1 - Clustering of Sex Hormone Disruptors in Singapore's Marine Environment AN - 14673151; 10649956 JF - Environmental Health Perspectives AU - Gong, Yinhan AU - Chin, Hong Soon AU - Lim, Lis Sa Elissa AU - Loy, Chong Jin AU - Obbard, Jeffrey P AU - Yong, EL Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1448 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SINGAPORE KW - HORMONAL EFFECTS KW - BIOASSAY KW - MEASUREMENTS AND SENSING KW - COASTAL WATERS KW - MARINE WATER ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673151?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Clustering+of+Sex+Hormone+Disruptors+in+Singapore%27s+Marine+Environment&rft.au=Gong%2C+Yinhan%3BChin%2C+Hong+Soon%3BLim%2C+Lis+Sa+Elissa%3BLoy%2C+Chong+Jin%3BObbard%2C+Jeffrey+P%3BYong%2C+EL&rft.aulast=Gong&rft.aufirst=Yinhan&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1448&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; COASTAL WATERS; SINGAPORE; HORMONAL EFFECTS; BIOASSAY; MARINE WATER ANALYSIS ER - TY - JOUR T1 - A Review of a Two-Phase Population Study of Multiple Chemical Sensitivities AN - 14673146; 10649963 AB - Results are summarized from a two-phase study that investigated the prevalence, symptomatology, and etiology of multiple chemical sensitivity (MCS). The first phase focused on the prevalence of the syndrome in the metropolitan Atlanta, GA, area, and the second consisted of a more extensive follow-up of the positive respondents found during the first phase. The results show that 12.6% of the respondents reported unusual sensitivity to common chemical substances, with an additional 1.4% not sure. In 12.4% of those reporting MCS, 12.4% reported the cause to be chemical exposure, and of those who reported sensitivities, 45.1% received medical treatment. Females comprised 71.7% of the respondents reporting hypersensitivity, but hypersensitivity was distributed widely across education levels. Individuals with a hypersensitivity displayed greater consistency in what triggered a reaction than in the type of symptoms they experienced after an exposure. For a substantial number of the respondents, their hypersensitivity was reported to be disruptive and life-altering. Very few of the respondents had a history of mental or emotional problems prior to the onset of their hypersensitivity. JF - Environmental Health Perspectives AU - Caress, Stanley M AU - Steinemann, Anne C Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1490 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHEMICAL CONTAMINATION, MULTIPLE KW - GEORGIA KW - SENSITIVITY KW - DISEASES AND DISORDERS KW - PATHOLOGY, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673146?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Review+of+a+Two-Phase+Population+Study+of+Multiple+Chemical+Sensitivities&rft.au=Caress%2C+Stanley+M%3BSteinemann%2C+Anne+C&rft.aulast=Caress&rft.aufirst=Stanley&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1490&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 13 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL CONTAMINATION, MULTIPLE; GEORGIA; SENSITIVITY; PATHOLOGY, HUMAN; DISEASES AND DISORDERS ER - TY - JOUR T1 - Octachlorodipropyl Ether (S-2) Mosquito Coils Are Inadequately Studied for Residential Use in Asia and Illegal in the United States AN - 14673108; 10649954 AB - Mosquito coils consist of an insecticide/repellent, organic fillers capable of burning with smoldering, binder, and additives. The coils burn for about 8 h without flame and are often used overnight in sleeping quarters in Asia. They often contain octachlorodipropyl ether (S-2) as a synergist or active ingredient, which may be volatilized from the coils and cause inhalation and contact exposures. Results are presented from a study in which mosquito coils sold in Indonesia and California were analyzed chemically. The coils from Indonesia contained up to five double coils and listed either allethrin only or allethrin and S-2 at 1.5%, while those purchased in southern California contained allethrin, and while the packages did not list-S-2, the content ranged 0.20.3%. None of the products manufactured in China and purchased in southern California was registered with EPA. JF - Environmental Health Perspectives AU - Krieger, Robert I AU - Dinoff, Travis M AU - Zhang, Xiaofei Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1439 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - INDONESIA KW - INSECTICIDES KW - MOSQUITOES KW - RISK ASSESSMENT KW - CALIFORNIA KW - INSECTICIDE EXPOSURE KW - BISCHLOROMETHYL ETHER KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14673108?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Octachlorodipropyl+Ether+%28S-2%29+Mosquito+Coils+Are+Inadequately+Studied+for+Residential+Use+in+Asia+and+Illegal+in+the+United+States&rft.au=Krieger%2C+Robert+I%3BDinoff%2C+Travis+M%3BZhang%2C+Xiaofei&rft.aulast=Krieger&rft.aufirst=Robert&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1439&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; INDONESIA; CALIFORNIA; INSECTICIDE EXPOSURE; INSECTICIDES; BISCHLOROMETHYL ETHER; MOSQUITOES ER - TY - JOUR T1 - Metal Composition of Ambient PM sub(2.5) Influences Severity of Allergic Airways Disease in Mice AN - 14672774; 10649960 JF - Environmental Health Perspectives AU - Gavett, Stephen H AU - Haykal-Coates, Najwa AU - Copeland, Lisa B AU - Heinrich, Joachim AU - Gilmour, MIan Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1471 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RESPIRATORY DISORDERS KW - GERMANY KW - URBAN ATMOSPHERE KW - PARTICULATES KW - IMMUNE RESPONSE KW - HEAVY METALS KW - ALLERGIES KW - PULMONARY EFFECTS KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672774?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Metal+Composition+of+Ambient+PM+sub%282.5%29+Influences+Severity+of+Allergic+Airways+Disease+in+Mice&rft.au=Gavett%2C+Stephen+H%3BHaykal-Coates%2C+Najwa%3BCopeland%2C+Lisa+B%3BHeinrich%2C+Joachim%3BGilmour%2C+MIan&rft.aulast=Gavett&rft.aufirst=Stephen&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1471&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEAVY METALS; RESPIRATORY DISORDERS; ALLERGIES; PULMONARY EFFECTS; RODENTS; PARTICULATES; URBAN ATMOSPHERE; GERMANY; IMMUNE RESPONSE ER - TY - JOUR T1 - Persistent Hematologic and Immunologic Disturbances in 8-Year-Old Dutch Children Associated with Perinatal Dioxin Exposure AN - 14672215; 10649967 AB - In 8-yr-old children who had been exposed to high dioxin levels in breast milk of Dutch mothers in 1986, persistent hematologic and immunologic disturbances were explored. All of the children were born to healthy, well-nourished Caucasian women aged 2338 yr. A decrease in allergy was observed in the study children, and a significant decrease in thrombocytes and a borderline increase in thrombopoietin concentrations were noted in relation to perinatal dioxin exposure, which indicated a production problem at the stem cell level. A significant increase was also found in T-helper cells in relation to increasing postnatal dioxin exposure. JF - Environmental Health Perspectives AU - ten Tusscher, Gavin W AU - Steerenberg, Peter A AU - van Loveren, Henk AU - Vos, Joseph G AU - von dem Borne, Albert EGK AU - Westra, Matthijs AU - van der Slikke, Johannes W Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1519 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - NETHERLANDS KW - BREAST MILK KW - DIOXINS KW - IMMUNE RESPONSE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672215?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Persistent+Hematologic+and+Immunologic+Disturbances+in+8-Year-Old+Dutch+Children+Associated+with+Perinatal+Dioxin+Exposure&rft.au=ten+Tusscher%2C+Gavin+W%3BSteerenberg%2C+Peter+A%3Bvan+Loveren%2C+Henk%3BVos%2C+Joseph+G%3Bvon+dem+Borne%2C+Albert+EGK%3BWestra%2C+Matthijs%3Bvan+der+Slikke%2C+Johannes+W&rft.aulast=ten+Tusscher&rft.aufirst=Gavin&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1519&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; NETHERLANDS; BREAST MILK; DIOXINS; IMMUNE RESPONSE ER - TY - JOUR T1 - Elevated Nitric Oxide/Peroxynitrite Theory of Multiple Chemical Sensitivity: Central Role of N-Methyl-D-Aspartate Receptors in the Sensitivity Mechanism AN - 14672018; 10649958 JF - Environmental Health Perspectives AU - Pall, Martin L Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1461 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHEMICAL CONTAMINATION, MULTIPLE KW - DISEASES AND DISORDERS KW - PATHOLOGY, HUMAN KW - OXIDANT STRESS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14672018?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Elevated+Nitric+Oxide%2FPeroxynitrite+Theory+of+Multiple+Chemical+Sensitivity%3A+Central+Role+of+N-Methyl-D-Aspartate+Receptors+in+the+Sensitivity+Mechanism&rft.au=Pall%2C+Martin+L&rft.aulast=Pall&rft.aufirst=Martin&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1461&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL CONTAMINATION, MULTIPLE; PATHOLOGY, HUMAN; DISEASES AND DISORDERS; OXIDANT STRESS ER - TY - JOUR T1 - The OECD Program to Validate the Rat Uterotrophic Bioassay. Phase 2: Coded Single-Dose Studies AN - 14671369; 10649970 AB - In an effort to validate standard protocols for the uterotrophic bioassay, OECD conducted coded single-dose studies using a potent reference agonist, five weak estrogen agonists, and a negative test substance. Four protocols were included to address the two primary versions of the assay, the intact, immature and the adult ovariectomized female rat, as well as oral gavage and subcutaneous injection as the routes of exposure. The reference agonist was 17 alpha -ethinylestradiol, and the weak estrogens were bisphenol A, genistein, methoxychlor, nonylphenol, and o,p'-DDT. The single doses selected were intended to be near the midpoint or in the upper half of a doseresponse curve. There was a consistent association in the studies between the occurrence of mortalities, reduced body-weight gain, and clinical signs with o,p'-DDT and nonylphenol in one protocol and for reduced body-weight gain with the high 17 alpha -ethinylestradiol dose, bisphenol A, and methoxychlor in another protocol. For each protocol, however, the mean relative increase in uterine weight was reproducible within and among laboratories for each test substance. JF - Environmental Health Perspectives AU - Kanno, Jun AU - Onyon, Lesley AU - Peddada, Shyamal AU - Ashby, John AU - Jacob, Elard AU - Owens, William Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1550 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - HORMONAL EFFECTS KW - BIOASSAY KW - ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT KW - RATS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+OECD+Program+to+Validate+the+Rat+Uterotrophic+Bioassay.+Phase+2%3A+Coded+Single-Dose+Studies&rft.au=Kanno%2C+Jun%3BOnyon%2C+Lesley%3BPeddada%2C+Shyamal%3BAshby%2C+John%3BJacob%2C+Elard%3BOwens%2C+William&rft.aulast=Kanno&rft.aufirst=Jun&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1550&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 10 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; HORMONAL EFFECTS; BIOASSAY; ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT; RATS ER - TY - JOUR T1 - The Relationship Between Air Pollution from Heavy Traffic and Allergic Sensitization, Bronchial Hyperresponsiveness, and Respiratory Symptoms in Dutch Schoolchildren AN - 14671320; 10649966 AB - The respiratory health of children from 24 schools situated within 400 m of a motorway was studied in the central southwestern part of the Netherlands. Exposure to traffic-related air pollution was assessed using specific traffic-related characteristics, along with estimated annual average concentrations of PM sub(2.5), soot, and nitrogen dioxide outside each school. The children were evaluated for serum immunoglobulin E, skin test reactivity, and bronchial hyperresponsiveness, and asthmatic and allergic symptoms were ascertained via questionnaire. In the schoolchildren living close to motorways, truck traffic and air pollutants associated with truck traffic were associated with chronic respiratory symptoms, but there was no association with car traffic and no association with bronchial hyperresponsiveness and sensitization to indoor allergens. Sensitization to outdoor allergens, however, was increased in children exposed to high truck traffic counts and associated air pollution concentrations. The associations between traffic-related air pollution and symptoms were much stronger in children with bronchial hyperresponsiveness and sensitization to common allergens than among those without the traits. JF - Environmental Health Perspectives AU - Janssen, Nicole AH AU - Brunekreef, Bert AU - van Vliet, Patricia AU - Aarts, Francee AU - Meliefste, Kees AU - Harssema, Hendrik AU - Fischer, Paul Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1512 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - TRUCK EMISSIONS KW - AIR POLLUTION EFFECTS KW - RESPIRATORY DISORDERS KW - SCHOOLS, NON US KW - PATHOLOGY, CHILDREN KW - NETHERLANDS KW - ALLERGIES KW - ASTHMA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14671320?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+Between+Air+Pollution+from+Heavy+Traffic+and+Allergic+Sensitization%2C+Bronchial+Hyperresponsiveness%2C+and+Respiratory+Symptoms+in+Dutch+Schoolchildren&rft.au=Janssen%2C+Nicole+AH%3BBrunekreef%2C+Bert%3Bvan+Vliet%2C+Patricia%3BAarts%2C+Francee%3BMeliefste%2C+Kees%3BHarssema%2C+Hendrik%3BFischer%2C+Paul&rft.aulast=Janssen&rft.aufirst=Nicole&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1512&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; TRUCK EMISSIONS; PATHOLOGY, CHILDREN; NETHERLANDS; RESPIRATORY DISORDERS; ALLERGIES; ASTHMA; SCHOOLS, NON US ER - TY - JOUR T1 - The Relationship Between Human Semen Parameters and Environmental Exposure to Polychlorinated Biphenyls and p,p'-DDE AN - 14668435; 10649965 AB - The male partners of subfertile couples who presented to the Vincent Burnham Andrology Laboratory at Massachusetts General Hospital were studied to assess the relationship between semen parameters and environmental exposure to PCBs and p,p'-DDE. The subjects were aged 2054 yr, and a questionnaire was used to collect information on medical history and lifestyle factors. Blood samples were collected on the same day as the semen samples and analyzed for PCBs and p,p-DDE. A doseresponse relationship was found between exposure to PCB-138 and decreased sperm concentration, sperm motility, and poor sperm morphology, and there was weak evidence of an association between p,p'-DDE and sperm motility. Limited evidence was also found of an inverse relationship of the sum of PCBs and cytochrome P450 enzyme inducers with sperm motility and sperm morphology. The data suggested that individual congeners and groupings of congeners based on structureactivity could represent a more appropriate approach to the analysis between PCBs and health endpoints. JF - Environmental Health Perspectives AU - Hauser, Russ AU - Chen, Zuying AU - Pothier, Lucille AU - Ryan, Louise AU - Altshul, Larisa Y1 - 2003/09// PY - 2003 DA - Sep 2003 SP - 1505 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - SEMEN KW - DDE KW - SPERM KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14668435?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+Between+Human+Semen+Parameters+and+Environmental+Exposure+to+Polychlorinated+Biphenyls+and+p%2Cp%27-DDE&rft.au=Hauser%2C+Russ%3BChen%2C+Zuying%3BPothier%2C+Lucille%3BRyan%2C+Louise%3BAltshul%2C+Larisa&rft.aulast=Hauser&rft.aufirst=Russ&rft.date=2003-09-01&rft.volume=111&rft.issue=12&rft.spage=1505&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; POLYCHLORINATED BIPHENYLS; SPERM; SEMEN; REPRODUCTION, HUMAN; DDE ER - TY - JOUR T1 - Cytotoxic activity of steroidal glycosides from solanum plants. AN - 73544437; 12913278 AB - Since some Solanum-genera plants have traditionally been used as anti-cancer and anti-herpes agents from olden times, we examined the cytotoxic activity of typical steroidal glycosides with the framework of spirostane, furostane, spirosolane, and pregnane obtained from Solanum plants. Among these steroidal glycosides, the spirostanol glycosides having a beta-lycotetraosyl moiety were the most effective against PC-12 and HCT-116 cell lines. The potency of activity was observed to be decreased in the order of spirostane, furostane, spirosolane, and pregnane type steroid glycosides. It was also suggested that the activity depend on the kind of oligosaccharide moiety and aglycone moiety. JF - Biological & pharmaceutical bulletin AU - Ikeda, Tsuyoshi AU - Tsumagari, Hidetsugu AU - Honbu, Takehiko AU - Nohara, Toshihiro AD - Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan. tikeda@gpo.kumamoto-u.ac.jp Y1 - 2003/08// PY - 2003 DA - August 2003 SP - 1198 EP - 1201 VL - 26 IS - 8 SN - 0918-6158, 0918-6158 KW - Cytotoxins KW - 0 KW - Glycosides KW - Phytosterols KW - Index Medicus KW - Rats KW - Animals KW - Humans KW - HCT116 Cells KW - PC12 Cells KW - Phytosterols -- pharmacology KW - Cytotoxins -- chemistry KW - Glycosides -- pharmacology KW - Glycosides -- chemistry KW - Cytotoxins -- toxicity KW - Phytosterols -- chemistry KW - Solanum -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73544437?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+%26+pharmaceutical+bulletin&rft.atitle=Cytotoxic+activity+of+steroidal+glycosides+from+solanum+plants.&rft.au=Ikeda%2C+Tsuyoshi%3BTsumagari%2C+Hidetsugu%3BHonbu%2C+Takehiko%3BNohara%2C+Toshihiro&rft.aulast=Ikeda&rft.aufirst=Tsuyoshi&rft.date=2003-08-01&rft.volume=26&rft.issue=8&rft.spage=1198&rft.isbn=&rft.btitle=&rft.title=Biological+%26+pharmaceutical+bulletin&rft.issn=09186158&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-04-07 N1 - Date created - 2003-08-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Raman spectroscopy of selected arsenates--implications for soil remediation. AN - 73531219; 12909138 AB - The contamination of soils with heavy metals such as As, Cr and Cu is of great importance; the remediation of such soils even more so. Arsenic compounds are prevalent in soils either through leaching of mine tailings, the use of Cu/Cr/As as a wood preservative or through the use of arsenic in cattle dips. The arsenic compounds in soils and leachates can be highly reactive and mobile, resulting in the formation of metal arsenate compounds. Of these compounds, one such set of minerals that can be formed is the vivianite arsenate minerals. Raman spectroscopy has been used to characterise the vivianite arsenates and to identify arsenic contaminants in a soil. JF - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy AU - Frost, Ray L AU - Kloprogge, Theo AU - Weier, Matthew L AU - Martens, Wayde N AU - Ding, Z AU - Edwards, Howell G H AD - Centre for Instrumental and Developmental Chemistry, Queensland University of Technology, 2 George Street, GPO Box 2434, Brisbane, Qld. 4001, Australia. r.frost@qut.edu.au Y1 - 2003/08// PY - 2003 DA - August 2003 SP - 2241 EP - 2246 VL - 59 IS - 10 SN - 1386-1425, 1386-1425 KW - Arsenates KW - 0 KW - Soil Pollutants KW - Index Medicus KW - Spectrum Analysis, Raman KW - Arsenates -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73531219?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.atitle=Raman+spectroscopy+of+selected+arsenates--implications+for+soil+remediation.&rft.au=Frost%2C+Ray+L%3BKloprogge%2C+Theo%3BWeier%2C+Matthew+L%3BMartens%2C+Wayde+N%3BDing%2C+Z%3BEdwards%2C+Howell+G+H&rft.aulast=Frost&rft.aufirst=Ray&rft.date=2003-08-01&rft.volume=59&rft.issue=10&rft.spage=2241&rft.isbn=&rft.btitle=&rft.title=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.issn=13861425&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-12 N1 - Date created - 2003-08-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - BOOK T1 - It's about time: research challenges in digital archiving and long-term preservation: final report, Workshop on Research Challenges in Digital Archiving and Long-Term Preservation, April 12-13, 2002 AN - 59945993; 2004-0107510 AB - Discusses unique challenges in archiving and digital preservation, danger of loss of digital information through obsolescence of technology, and recommends a research agenda; US. Sponsored jointly by the National Science Foundation, Digital Government Program and Digital Libraries Program, Directorate for Computing and Information Sciences and Engineerin, and the Library of Congress, National Digital Information Infrastructure and Preservation Program. JF - United States Library of Congress, August 2003. Y1 - 2003/08// PY - 2003 DA - August 2003 PB - United States Library of Congress KW - Archives -- Conservation and restoration KW - Information technology -- United States KW - United States -- Educational sector KW - Digital preservation -- United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59945993?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2003-08-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=It%27s+about+time%3A+research+challenges+in+digital+archiving+and+long-term+preservation%3A+final+report%2C+Workshop+on+Research+Challenges+in+Digital+Archiving+and+Long-Term+Preservation%2C+April+12-13%2C+2002&rft.title=It%27s+about+time%3A+research+challenges+in+digital+archiving+and+long-term+preservation%3A+final+report%2C+Workshop+on+Research+Challenges+in+Digital+Archiving+and+Long-Term+Preservation%2C+April+12-13%2C+2002&rft.issn=&rft_id=info:doi/ L2 - http://www.digitalpreservation.gov/repor/NSF_LC_Final_Report.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Lib Cong N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Stable gene transformation in cowpea (Vigna unguiculata L. walp.) using particle gun method AN - 19894872; 7728997 AB - We investigated the possibility of transforming and obtaining transgenic cowpea (Vigna unguiculata L Walp) plants using the particle bombardment process. Meristematic explants that could give rise to whole fertile plants were used in transformation experiments with reporter and selectable marker genes driven by a 35S CaMV promoter. Conditions for optimal delivery of DNA to explants were established based on transient gus expression assays two days after bombardment. The size of microcarriers, microflight distance and helium pressure significantly affected transient expression of reporter genes. A total of 1692 explants were bombarded with DNA-coated particles and placed on 3 mg/1 bialaphos selective medium. Only 12 regenerated shoots produced seeds eventually, and all were Gus negative even though 7 gave positive PCR signals with the bar primer. Eight out of 1400 seeds from T sub(0) plants were GUS positive. DNA from eight of the GUS positive seedlings were amplified with both the gus and bar primers in PCR analysis but only two gave a positive Southern signal. Only two of the 3557 T sub(2) seedlings obtained were GUS positive. However, 3 seedlings survived Basta spray. The two GUS positive and 3 Basta surviving seedlings gave positive Southern hybridisation signals. Twelve T sub(3) seedlings from these were GUS positive and also gave positive Southern hybridisation signals. The positive reaction of T sub(1), T sub(2) and T sub(3) seedlings under Southern analysis confirms the stable integration of introduced genes and the transfer of such genes to progenies. However, the level of expression of introduced genes in cowpea cells is very low and this accounted for the high mortality rate of progenies under Basta spray. JF - African Journal of Biotechnology AU - Ikea, J AU - Ingelbrecht, I AU - Uwaifo, A AU - Thottappffly, G AD - CSIRO Plant Industry, Black Mountain Laboratories, G.P.O Box 1600, Canberra ACT 2601, Australia, Joe.Ikea@csiro.au Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 211 EP - 218 VL - 2 IS - 8 SN - 1684-5315, 1684-5315 KW - Genetics Abstracts; Biotechnology and Bioengineering Abstracts KW - Transformation KW - Mortality KW - Seeds KW - bialaphos KW - particle bombardment KW - Transgenic plants KW - Vigna unguiculata KW - Shoots KW - Integration KW - Promoters KW - Helium KW - Polymerase chain reaction KW - Progeny KW - Seedlings KW - Primers KW - Pressure KW - Explants KW - W 30925:Genetic Engineering KW - G 07800:Plants and Algae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19894872?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=African+Journal+of+Biotechnology&rft.atitle=Stable+gene+transformation+in+cowpea+%28Vigna+unguiculata+L.+walp.%29+using+particle+gun+method&rft.au=Ikea%2C+J%3BIngelbrecht%2C+I%3BUwaifo%2C+A%3BThottappffly%2C+G&rft.aulast=Ikea&rft.aufirst=J&rft.date=2003-08-01&rft.volume=2&rft.issue=8&rft.spage=211&rft.isbn=&rft.btitle=&rft.title=African+Journal+of+Biotechnology&rft.issn=16845315&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Transformation; Mortality; Seeds; bialaphos; particle bombardment; Transgenic plants; Shoots; Promoters; Integration; Polymerase chain reaction; Helium; Primers; Seedlings; Progeny; Pressure; Explants; Vigna unguiculata ER - TY - BOOK T1 - Views of the workers AN - 19700700; 7481059 AB - This paper is written from the perspective of the worker. As such it presents the workers' viewpoint with respect to the present status and problems to be solved with regard to occupational exposure. JF - OCCUPATIONAL RADIATION PROTECTION: PROTECTING WORKERS AGAINST EXPOSURE TO IONIZING RADIATION. AU - Tudor, O Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1 EP - 129 PB - International Atomic Energy Agency, PO Box 100 Vienna A-1400 Austria, [URL:http://www.iaea.org] KW - Pollution Abstracts; Health & Safety Science Abstracts KW - Conferences KW - Ionizing radiation KW - Occupational exposure KW - H 8000:Radiation Safety/Electrical Safety KW - P 8000:RADIATION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19700700?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Pollution+Abstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Tudor%2C+O&rft.aulast=Tudor&rft.aufirst=O&rft.date=2003-08-01&rft.volume=&rft.issue=&rft.spage=129&rft.isbn=&rft.btitle=Views+of+the+workers&rft.title=Views+of+the+workers&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 ER - TY - JOUR T1 - Aryl Hydrocarbon Receptor-Mediated Activity of Particulate Organic Matter from the Paso del Norte Airshed along the U.S.-Mexico Border AN - 19423515; 5711823 AB - In this study, we determined the biologic activity of dichloromethane-extracted particulate matter < 10 mu m in aerodynamic diameter (PM sub(10)) obtained from filters at three sites in the Paso del Norte airshed, which includes El Paso, Texas, USA; Juarez, Chihuahua, Mexico, and Sunland Park, New Mexico, USA. The extracts were rich in polycyclic aromatic hydrocarbons (PAHs) and had significant biologic activity, measured using two in vitro assay systems: ethoxyresorufin-O-deethylase (EROD) induction and the aryl hydrocarbon-receptor luciferase reporter system. In most cases, both EROD (5.25 pmol/min/mg protein) and luciferase activities (994 relative light units/mg) were highest in extracts from the Advance site located in an industrial neighborhood in Juarez. These values represented 58% and 55%, respectively, of induction associated with 1 mu M beta -naphthoflavone exposures. In contrast, little activity was observed at the Northeast Clinic site in El Paso, the reference site. In most cases, luciferase and EROD activity from extracts collected from the Tillman Health Center site, situated in downtown El Paso, fell between those observed at the other two sites. Overall, a statistically significant correlation existed between PM sub(10) and EROD and luciferase activities. Chemical analysis of extracts collected from the Advance site demonstrated that concentrations of most PAHs were higher than those reported in most other metropolitan areas in the United States. Calculations made with these data suggest a cancer risk of 5-12 cases per 100,000 people. This risk estimate, as well as comparisons with the work of other investigators, raises concern regarding the potential for adverse health effects to the residents of this airshed. Further work is needed to understand the sources, exposure, and effects of PM sub(10) and particulate organic material in the Paso del Norte airshed. JF - Environmental Health Perspectives AU - Arrieta, DE AU - Ontiveros, C C AU - Li, W-W AU - Garcia, J H AU - Denison AU - McDonald, J D AU - Burchiel, S W AU - Washburn, B S AD - Dept. of Environmental Toxicology, 4209 Meyer Hall, 1 Shields Ave., University of California, Davis, CA 95616-8521, USA, dearrieta@ucdavis.edu Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1299 EP - 1305 PB - NIH, Government Printing Office VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - aryl hydrocarbon receptor luciferase reporter system KW - Pollution Abstracts; Toxicology Abstracts; Meteorological & Geoastrophysical Abstracts KW - USA, New Mexico KW - Polycyclic aromatic hydrocarbons KW - Atmospheric pollution KW - Organic matter KW - Statistical analysis KW - Correlations KW - Particulates KW - Cancer KW - Filters KW - Particulate matter in atmosphere KW - Mexico KW - Airborne particulates KW - Aerodynamics KW - Atmospheric pollution and health KW - Proteins KW - polycyclic aromatic hydrocarbons KW - Mexico, Chihuahua KW - USA, Texas KW - Chemical analysis KW - metropolitan areas KW - 7-Ethoxyresorufin O-deethylase KW - M2 551.510.42:Air Pollution (551.510.42) KW - X 24156:Environmental impact KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19423515?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Aryl+Hydrocarbon+Receptor-Mediated+Activity+of+Particulate+Organic+Matter+from+the+Paso+del+Norte+Airshed+along+the+U.S.-Mexico+Border&rft.au=Arrieta%2C+DE%3BOntiveros%2C+C+C%3BLi%2C+W-W%3BGarcia%2C+J+H%3BDenison%3BMcDonald%2C+J+D%3BBurchiel%2C+S+W%3BWashburn%2C+B+S&rft.aulast=Arrieta&rft.aufirst=DE&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1299&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6058 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-02-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Polycyclic aromatic hydrocarbons; Airborne particulates; Organic matter; 7-Ethoxyresorufin O-deethylase; Particulate matter in atmosphere; Atmospheric pollution; Atmospheric pollution and health; Correlations; Statistical analysis; Filters; Aerodynamics; polycyclic aromatic hydrocarbons; Proteins; Particulates; metropolitan areas; Chemical analysis; Cancer; USA, New Mexico; Mexico; Mexico, Chihuahua; USA, Texas DO - http://dx.doi.org/10.1289/ehp.6058 ER - TY - JOUR T1 - Temperature, Air Pollution, and Hospitalization for Cardiovascular Diseases among Elderly People in Denver AN - 19398402; 5711825 AB - Daily measures of maximum temperature, particulate matter less than or equal to 10 mu m in aerodynamic diameter (PM sub(10)), and gaseous pollution (ozone, nitrogen dioxide, sulfur dioxide, and carbon monoxide) were collected in Denver, Colorado, in July and August between 1993 and 1997. We then compared these exposures with concurrent data on the number of daily hospital admissions for cardiovascular diseases in men and women > 65 years of age. Generalized linear models, assuming a Poisson error structure for the selected cardiovascular disease hospital admissions, were constructed to evaluate the associations with air pollution and temperature. After adjusting the admission data for yearly trends, day-of-week effects, ambient maximum temperature, and dew point temperature, we studied the associations of the pollutants in single-pollutant models with lag times of 0-4 days. The results suggest that O sub(3) is associated with an increase in the risk of hospitalization for acute myocardial infarction, coronary atherosclerosis, and pulmonary heart disease. SO sub(2) appears to be related to increased hospital stays for cardiac dysrhythmias, and CO is significantly associated with congestive heart failure. No association was found between particulate matter or NO sub(2) and any of the health outcomes. Males tend to have higher numbers of hospital admissions than do females for all of the selected cardiovascular diseases, except for congestive heart failure. Higher temperatures appear to be an important factor in increasing the frequency of hospitalization for acute myocardial infarction and congestive heart failure, and are associated with a decrease in the frequency of visits for coronary atherosclerosis and pulmonary heart disease. JF - Environmental Health Perspectives AU - Koken, PJM AU - Piver, W T AU - Ye, F AU - Elixhauser, A AU - Olsen, L M AU - Portier, C J AD - National Institute of Environmental Health Sciences, MD A3-06, PO Box 12233, Research Triangle Park, NC 27709, USA, koken@niehs.nih.gov Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1312 EP - 1317 PB - NIH, Government Printing Office VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - elderly KW - man KW - Toxicology Abstracts; Health & Safety Science Abstracts; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - Cardiovascular system KW - Environmental health KW - Particulates KW - Nitrogen dioxide KW - Carbon monoxide KW - Sulfur dioxide KW - Maximum temperatures KW - USA, Colorado, Denver KW - Atmospheric pollution and health KW - Geriatrics KW - Diseases KW - Ozone KW - Temperature effects KW - Atmospheric pollution KW - Coronal studies KW - Temperature KW - Particulate atmospheric pollution KW - Air pollution KW - USA, Colorado KW - Temperature trends KW - Cardiovascular diseases KW - Dew point temperatures KW - Hospitals KW - M2 551.510.42:Air Pollution (551.510.42) KW - X 24156:Environmental impact KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19398402?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Temperature%2C+Air+Pollution%2C+and+Hospitalization+for+Cardiovascular+Diseases+among+Elderly+People+in+Denver&rft.au=Koken%2C+PJM%3BPiver%2C+W+T%3BYe%2C+F%3BElixhauser%2C+A%3BOlsen%2C+L+M%3BPortier%2C+C+J&rft.aulast=Koken&rft.aufirst=PJM&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1312&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5957 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-02-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Temperature effects; Air pollution; Cardiovascular system; Geriatrics; Diseases; Coronal studies; Atmospheric pollution; Maximum temperatures; Atmospheric pollution models; Atmospheric pollution and health; Temperature trends; Cardiovascular diseases; Dew point temperatures; Particulate atmospheric pollution; Ozone; Carbon monoxide; Nitrogen dioxide; Sulfur dioxide; Temperature; Environmental health; Particulates; Hospitals; USA, Colorado; USA, Colorado, Denver DO - http://dx.doi.org/10.1289/ehp.5957 ER - TY - JOUR T1 - Proinflammatory and Cytotoxic Effects of Mexico City Air Pollution Particulate Matter in Vitro Are Dependent on Particle Size and Composition AN - 19396271; 5711821 AB - Exposure to urban airborne particulate matter (PM) is associated with adverse health effects. We previously reported that the cytotoxic and proinflammatory effects of Mexico City PM sub(10) ( less than or equal to 10 mu m mean aerodynamic diameter) are determined by transition metals and endotoxins associated with these particles. However, PM sub(2.5) ( less than or equal to 2.5 mu m mean aerodynamic diameter) could be more important as a human health risk because this smaller PM has the potential to reach the distal lung after inhalation. In this study, we compared the cytotoxic and proinflammatory effects of Mexico City PM sub(10) with those of PM sub(2.5) using the murine monocytic J774A.1 cell line in vitro. PMs were collected from the northern zone or the southeastern zone of Mexico City. Elemental composition and bacterial endotoxin on PMs were measured. Tumor necrosis factor- alpha (TNF- alpha ) and interleukin-6 (IL-6) production by J774A.1 cells was measured in the presence or absence of recombinant endotoxin-neutralizing protein (rENP). Both northern and southeastern PMs contained endotoxin and a variety of transition metals. Southeastern PM sub(10) contained the highest endotoxin levels, 2-fold higher than that in northern PM sub(10). Northern and southeastern PM sub(2.5) contained the lowest endotoxin levels. Accordingly, southeastern PM sub(10) was the most potent in causing secretion of the proinflammatory cytokines TNF- alpha and IL-6. All PM sub(2.5) and PM sub(10) samples caused cytotoxicity, but northern PMs were the most toxic. Cytokine secretion induced by southeastern PM sub(10) was reduced 50-75% by rENP. These results indicate major differences in PM sub(10) and PM sub(2.5). PM sub(2.5) induces cytotoxicity in vitro through an endotoxin-independent mechanism that is likely mediated by transition metals. In contrast, PM sub(10) with relatively high levels of endotoxin induces proinflammatory cytokine release via an endotoxin-dependent mechanism. JF - Environmental Health Perspectives AU - Osornio-Vargas, A R AU - Bonner, J C AU - Alfaro-Moreno, E AU - Martinez, L AU - Garcia-Cuellar, C AU - Ponce-de-Leon Rosales, S AU - Miranda, J AU - Rosas, I AD - Division de Investigacion Basica, Instituto Nacional de Cancerologia, Av. San Fernando 22, Tlalpan, Mexico, DF 14080, Mexico, arov@servidor.unam.mx Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1289 EP - 1293 PB - NIH, Government Printing Office VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - mice KW - Microbiology Abstracts B: Bacteriology; Toxicology Abstracts; Health & Safety Science Abstracts; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Risk assessment KW - Inhalation KW - Interleukin 6 KW - Endotoxins KW - Particulate matter KW - Environmental health KW - Particulate matter in urban air KW - Transition metals KW - Mexico, Distrito Federal, Mexico City KW - Particulate matter in atmosphere KW - Airborne particulates KW - Atmospheric pollution and health KW - Mexico, Mexico City KW - Cytokines KW - Monocytes KW - Urban areas KW - Particle size KW - Chemical composition KW - Atmospheric pollution KW - Atmospheric pollution effects KW - Particulate atmospheric pollution KW - Inflammation KW - Air pollution KW - Cytotoxicity KW - Lung KW - Urban atmospheric pollution KW - Tumor necrosis factor- alpha KW - M2 551.510.42:Air Pollution (551.510.42) KW - X 24156:Environmental impact KW - J 02400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19396271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Proinflammatory+and+Cytotoxic+Effects+of+Mexico+City+Air+Pollution+Particulate+Matter+in+Vitro+Are+Dependent+on+Particle+Size+and+Composition&rft.au=Osornio-Vargas%2C+A+R%3BBonner%2C+J+C%3BAlfaro-Moreno%2C+E%3BMartinez%2C+L%3BGarcia-Cuellar%2C+C%3BPonce-de-Leon+Rosales%2C+S%3BMiranda%2C+J%3BRosas%2C+I&rft.aulast=Osornio-Vargas&rft.aufirst=A&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1289&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5913 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-02-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Endotoxins; Interleukin 6; Inhalation; Particle size; Particulate matter; Transition metals; Inflammation; Air pollution; Cytotoxicity; Airborne particulates; Lung; Cytokines; Tumor necrosis factor- alpha; Monocytes; Particulate matter in atmosphere; Atmospheric pollution; Atmospheric pollution and health; Atmospheric pollution effects; Urban atmospheric pollution; Particulate matter in urban air; Particulate atmospheric pollution; Risk assessment; Chemical composition; Environmental health; Urban areas; Mexico, Mexico City; Mexico, Distrito Federal, Mexico City DO - http://dx.doi.org/10.1289/ehp.5913 ER - TY - JOUR T1 - Relationship Between Internal Phase Volume and Emulsion Stability: The Cetyl Alcohol/Stearyl Alcohol System AN - 18956992; 5710920 AB - The main objective of this study was to optimize the stability of cetyl alcohol/stearyl alcohol emulsions in terms of percentage of internal phase volume, emulsifier type and concentration, and amount of external phase (water). Creams (o/w emulsions) were prepared by phase inversion and physical properties as particle size of the internal phase, apparent viscosity, and sedimentation volume evaluated. Stability was performed at room temperature, 40 degree C, 50 degree C, and under stress conditions. High hydrophilic lipophilic balance (HLB) nonionic surfactants as tween 80, tween 20, Myrj 52, Brij 35, and low HLB span 60 were used as emulsifying agents. The percentage of internal phase components (cetyl alcohol and stearyl alcohol), percentage of emulsifying agents, and percentage of aqueous external phase were varied, and stability was investigated. As the level of emulsifier agent (tween 80 and span 60) increased from 3% to 15%, and the percent of the internal phase remained constant at 30%, the particle size of the internal phase decreased and the cream became more stable. Formulations of the same composition, but prepared using Myrj 53 and tween 20 as emulsifiers, showed a larger particle size than formulations prepared using tween 80 and Brij 35. As the level of the internal phase volume increased and consequently the amount of water decreased, emulsion viscosity increased. The best formulation containing 30% internal phase (50% cetyl alcohol, 35% stearyl alcohol), 15% emulsifying agents (tween 80/span 60 ratio of 3:1), and 70% water was selected, and effects of process temperature and cooling rate on emulsion stability investigated. This formulation was further investigated in terms of stability of a 1% hydrocortisone addition by varying the percentage (30%, 35%, 40%, and 45%) of internal phase and percentage of water (70%, 65%, 60%, and 55%). The best formulation contained 45% internal phase (22.5 g cetyl alcohol, 15.75 g stearyl alcohol, 15% emulsifying agent, which is equivalent to 5 g tween 80 and 1.7 g span 60), and 55% w/w water, was manufactured under different manufacturing processes. Emulsions prepared by homogenization at the beginning of the process of emulsification were stable with small internal phase particle diameter. This study demonstrates that at every cetyl alcohol/stearyl alcohol ratio there is a phase volume/emulsifier HLB ratio, which results in optimum stability. JF - Pharmaceutical Development and Technology AU - Sepulveda, E AU - Kildsig, DO AU - Ghaly, E S AD - School of Pharmacy, Medical Sciences Campus, University of Puerto Rico, G.P.O. Box 365067, San Juan, PR 00936-5067, USA, eghaly@rcm.upr.edu Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 263 EP - 275 VL - 8 IS - 3 SN - 1083-7450, 1083-7450 KW - alcohols KW - cetyl alcohol KW - stearyl alcohol KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Drug delivery KW - Emulsifiers KW - Emulsions KW - W4 130:General Biomedical Engineering: Tools & Techniques KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18956992?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmaceutical+Development+and+Technology&rft.atitle=Relationship+Between+Internal+Phase+Volume+and+Emulsion+Stability%3A+The+Cetyl+Alcohol%2FStearyl+Alcohol+System&rft.au=Sepulveda%2C+E%3BKildsig%2C+DO%3BGhaly%2C+E+S&rft.aulast=Sepulveda&rft.aufirst=E&rft.date=2003-08-01&rft.volume=8&rft.issue=3&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=Pharmaceutical+Development+and+Technology&rft.issn=10837450&rft_id=info:doi/10.1081%2FPDT-120022155 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Emulsions; Drug delivery; Emulsifiers DO - http://dx.doi.org/10.1081/PDT-120022155 ER - TY - JOUR T1 - Expression of Drosophila Ca super(2+) permeable transient receptor potential-like channel protein in a prostate cancer cell line decreases cell survival AN - 18942500; 5709149 AB - The effects of expression of Drosophila melanogaster Ca super(2+) permeable transient receptor potential-like (TRPL) channels, under the control of the cytomegalovirus (CMV) or prostate cell-specific promoters, on cell survival and apoptosis in the androgensensitive LNCaP prostate cancer cell line were investigated. A prostate-specific antigen (PSA) promoter construct (designated PSAEn/PSAPr) composed of a 0.6 kb region of the promoter and a 1.45 kb region of the enhancer resulted in androgen-dependent and prostate-specific expression of a luciferase reporter gene in transiently transfected LNCaP cells. Expression of the enhanced green fluorescence protein-TRPL chimeric protein under the control of the CMV promoter was confirmed by Western blot. Whereas the majority of the expressed protein was located in the cytoplasmic space, confocal microscopy with the CD-9 protein as a plasma membrane marker demonstrated that approximately 10% of the expressed TRPL protein was located in a band in the plasma membrane. Using recombinant adenoviruses, expression of the TRPL protein was associated with an increase in both the initial and sustained rates of Ca super(2+) inflow. Expression of TRPL under the control of the CMV promoter for 96 hours decreased cell number and increased the number of cells undergoing apoptosis by 23 and 27%, respectively. Apoptosis was inhibited by a caspase-3 inhibitor, Z-DEVD-fmk. It is concluded that, when heterologously expressed in LNCaP cells, the TRPL protein leads to a reduction in cell survival due, in part, to the induction of apoptosis. The effects of TRPL are likely caused by enhanced Na super(+) and Ca super(2+) inflow to the cells. This finding suggests a novel approach to modify the growth of prostate cancer cells that fail to undergo apoptosis following androgen ablation therapy. JF - Cancer Gene Therapy AU - Zhang, L AU - Brereton, H M AU - Hahn, M AU - Froscio, M AU - Tilley, W D AU - Brown, M P AU - Barritt, G J AD - Department of Medical Biochemistry, School of Medicine, Faculty of Health Sciences, Flinders University, GPO Box 2100, Adelaide, South Australia, 5001, Australia, Greg.Barritt@flinders.edu.au Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 611 EP - 625 VL - 10 IS - 8 SN - 0929-1903, 0929-1903 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Western blotting KW - Gene therapy KW - Reporter gene KW - Drosophila melanogaster KW - Calcium channels KW - Green fluorescent protein KW - Prostate KW - Cancer KW - W 30965:Miscellaneous, Reviews KW - W4 120:Genetic Engineering in Medicine KW - W3 33180:Gene based (protocols, clinical trials, and animal models) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18942500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+Gene+Therapy&rft.atitle=Expression+of+Drosophila+Ca+super%282%2B%29+permeable+transient+receptor+potential-like+channel+protein+in+a+prostate+cancer+cell+line+decreases+cell+survival&rft.au=Zhang%2C+L%3BBrereton%2C+H+M%3BHahn%2C+M%3BFroscio%2C+M%3BTilley%2C+W+D%3BBrown%2C+M+P%3BBarritt%2C+G+J&rft.aulast=Zhang&rft.aufirst=L&rft.date=2003-08-01&rft.volume=10&rft.issue=8&rft.spage=611&rft.isbn=&rft.btitle=&rft.title=Cancer+Gene+Therapy&rft.issn=09291903&rft_id=info:doi/10.1038%2Fsj.cgt.7700608 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Drosophila melanogaster; Prostate; Cancer; Green fluorescent protein; Reporter gene; Gene therapy; Calcium channels; Western blotting DO - http://dx.doi.org/10.1038/sj.cgt.7700608 ER - TY - JOUR T1 - Persistence of Conidia of Metarhizium anisopliae in Sugarcane Fields: Effect of isolate and formulation on persistence over 3.5 years AN - 18834588; 5725370 AB - Metarhizium anisopliae is being used in Australia as a biopesticide for control of sugarcane whitegrubs in soil. The field persistence in sugarcane soil of two isolates of M. anisopliae each in four formulations was tested by mixing the formulation with soil which was then placed in PVC rings and buried in sugarcane fields. The two isolates used were FI-1045, M. anisopliae var. anisopliae, the active ingredient in BioCane currently used for greyback canegrub control, Dermolepida albohirtum (Coleoptera: Scarabaeidae: Melolonthinae), and FI-147, M. anisopliae var. lepidiotum, being tested as a biopesticide for Lepidiota spp. (Coleoptera: Scarabaeidae: Melolonthinae) and other species of canegrub. The four formulations were rice granules (as in BioCane), a wettable powder derived from conidia screened from the rice granules, conidia off rice suspended in water and conidia produced on agar plates, dried, and then mixed with water for adding to soil. FI-1045 was tested at three different sites in north Queensland with a range of soil types and climatic conditions while FI-147 was tested at three similarly diverse sites in southern Queensland. The PVC rings were destructively sampled every 6 months for 3.5 years and the number of viable conidia remaining determined by plating onto a selective medium. The exponential decay was determined. Monthly decay rates ranged from 0.0309 to 0.0835 (mean 0.0512). A small proportion of conidia survived the 3.5 years at all sites and all formulations. Overall, isolate FI-147 persisted better than FI-1045, but was used at the more Southerly sites. Rainfall and soil type had negligible effects on persistence. The agar-produced FI-147 conidia declined most slowly, while the two rice-produced but water-formulated conidia gave similar results. Isolate FI-1045 survived best as the BioCane formulation and this rice granule formulation was almost as persistent as the agar conidia with FI-147. A small proportion of conidia, in some formulations and at some sites, were recovered from immediately below the rings. This movement was thought to be due to activity of earthworms or mites. The results suggest that 3 years would be the maximum period for a BioCane formulation to provide some level of infection in the target pest unless augmented by conidia from infected grubs. The effectiveness of these new conidia may be reduced due to their highly aggregated distribution. JF - Biocontrol Science and Technology AU - Milner, R J AU - Samson, P AU - Morton, R AD - CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia, richardm@ento.csiro.au Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 507 EP - 516 VL - 13 IS - 5 SN - 0958-3157, 0958-3157 KW - Sugarcane KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - K 03095:Soil KW - A 01030:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18834588?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biocontrol+Science+and+Technology&rft.atitle=Persistence+of+Conidia+of+Metarhizium+anisopliae+in+Sugarcane+Fields%3A+Effect+of+isolate+and+formulation+on+persistence+over+3.5+years&rft.au=Milner%2C+R+J%3BSamson%2C+P%3BMorton%2C+R&rft.aulast=Milner&rft.aufirst=R&rft.date=2003-08-01&rft.volume=13&rft.issue=5&rft.spage=507&rft.isbn=&rft.btitle=&rft.title=Biocontrol+Science+and+Technology&rft.issn=09583157&rft_id=info:doi/10.1080%2F0958315031000140965 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1080/0958315031000140965 ER - TY - JOUR T1 - Coxiella burnetii express type IV secretion system proteins that function similarly to components of the Legionella pneumophila Dot/Icm system AN - 18825902; 5711627 AB - Coxiella burnetii is an obligate intracellular pathogen that replicates in large endocytic vacuoles. Genomic sequence data indicate that 21 genes encoding products that are similar to components of the Legionella pneumophila Dot/Icm type IV secretion system are located on a contiguous 35 kb region of the Coxiella chromosome. It was found that several dot/icm genes were expressed by Coxiella during host cell infection and that dot/icm gene expression preceded the formation of large replicative vacuoles. To determine whether these genes encode a functional type IV secretion system, we have amplified the Coxiella dotB, icmQ, icmS and icmW genes and produced the encoded proteins in Legionella mutants in which the native copy of each gene had been deleted. The Coxiella dotB, icmS and icmW products restored dot /icm-dependent growth of Legionella mutants in eukaryotic host cells. The Coxiella IcmQ protein and the Legionella IcmR protein did not interact, which could explain why the Coxiella icmQ gene was unable to restore growth to a Legionella icmQ mutant. Thus, Coxiella encodes functional components of a type IV secretion system expressed in vivo that is mechanistically related to the Legionella Dot/Icm apparatus. These studies suggest that a dot/icm-related secretion system could play an important role in creating the specialized vacuole that supports Coxiella replication. JF - Molecular Microbiology AU - Zamboni, D S AU - McGrath, S AU - Rabinovitch, M AU - Roy, C R AD - Departamento de Microbiologia, Imunologia e Parasitologia, Yale University School of Medicine, Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Room 354, 295 Congress Avenue, New Haven, CT 06536, USA., craig.roy@yale.edu Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 965 EP - 976 PB - Blackwell Science Ltd VL - 49 IS - 4 SN - 0950-382X, 0950-382X KW - IcmQ protein KW - IcmR protein KW - dotB gene KW - icmQ gene KW - icmR gene KW - icmS gene KW - icmW gene KW - secretion system type IV KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology KW - G 07320:Bacterial genetics KW - J 02740:Genetics and evolution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18825902?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+Microbiology&rft.atitle=Coxiella+burnetii+express+type+IV+secretion+system+proteins+that+function+similarly+to+components+of+the+Legionella+pneumophila+Dot%2FIcm+system&rft.au=Zamboni%2C+D+S%3BMcGrath%2C+S%3BRabinovitch%2C+M%3BRoy%2C+C+R&rft.aulast=Zamboni&rft.aufirst=D&rft.date=2003-08-01&rft.volume=49&rft.issue=4&rft.spage=965&rft.isbn=&rft.btitle=&rft.title=Molecular+Microbiology&rft.issn=0950382X&rft_id=info:doi/10.1046%2Fj.1365-2958.2003.03626.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1046/j.1365-2958.2003.03626.x ER - TY - JOUR T1 - Diminished Experience-Dependent Neuroanatomical Plasticity: Evidence for an Improved Biomarker of Subtle Neurotoxic Damage to the Developing Rat Brain AN - 18825672; 5711822 AB - Millions of children are exposed to low levels of environmental neurotoxicants as their brains are developing. Conventional laboratory methods of neurotoxicology can detect maldevelopment of brain structure but are not designed to detect maldevelopment of the brain's capacity for plasticity that could impair learning throughout life. The environmental complexity (EC) paradigm has become classic for demonstrating the modifications in brain structure that occur in response to experience and thus provides a set of indices for plasticity in the healthy brain. In this study, we have tested the hypothesis that if degradation of experience-dependent cortical plasticity is used as a biomarker, then developmental neurotoxic effects will be detected at doses below those that alter cortical morphogenesis overtly. Pregnant Long-Evans hooded rats received a single injection of either saline vehicle or 1, 5, 10, or 25 mg/kg of the well-characterized developmental neurotoxicant methylazoxymethanol acetate (MAM) on the 16th or 17th day of gestation. On postnatal days 35-39, mate offspring were assigned to either a complex environment (EC) or an individual cage (IC) for 28 days to stimulate neuroanatomical plasticity. This response was measured as the difference between the thickness of visual cortex of IC and EC littermates at a given dose. The threshold dose for significant reduction of cortical thickness was 25 mg/kg, but the threshold dose for failure of plasticity was much lower and could be detected at 1 mg/kg, the lowest dose used. No other method of assessment has detected lasting effects of prenatal exposure to MAM at such a low dose. These data suggest that this simple test of plasticity could be an efficient way to detect subtle neurotoxic damage to the developing brain. JF - Environmental Health Perspectives AU - Wallace, C S AU - Reitzenstein, J AU - Withers, G S AD - Dept. of Biology, Whitman College, 345 Boyer Ave., Walla, WA 99362, USA, wallaccs@whitman.edu Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1294 EP - 1298 PB - NIH, Government Printing Office VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - biomarkers KW - development KW - rats KW - Toxicology Abstracts KW - X 24240:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18825672?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Diminished+Experience-Dependent+Neuroanatomical+Plasticity%3A+Evidence+for+an+Improved+Biomarker+of+Subtle+Neurotoxic+Damage+to+the+Developing+Rat+Brain&rft.au=Wallace%2C+C+S%3BReitzenstein%2C+J%3BWithers%2C+G+S&rft.aulast=Wallace&rft.aufirst=C&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1294&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6088 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.6088 ER - TY - JOUR T1 - Distribution and Determinants of Mouse Allergen Exposure in Low-Income New York City Apartments AN - 18824439; 5711829 AB - Previous studies of mouse allergens and laboratory-animal-worker-related allergy and asthma suggest that quantifying mouse allergen levels in homes could augment our understanding of inner-city asthma. We hypothesized that levels of mouse allergen in inner-city homes would be related to certain household characteristics. Dust samples were collected from the kitchens and beds of 221 mothers enrolled in a prospective birth cohort study, 92 of African American and 129 of Dominican ethnicity. Samples were analyzed for mouse urinary protein. The geometric mean for kitchen samples was 4.6 mu g/g [95% confidence interval (95% CI), 3.2-6.51 and for bed samples was 0.9 mu g/g (95% CI, 0.8-1.1). The variables associated with mouse allergen levels in the home were frequency of mouse sightings, use of traps or pesticides for mice, presence of holes in ceilings or walls, absence of a cat, and living in a building with fewer than eight floors. Statistically significant neighborhood differences in levels of mouse allergen and report of rodents in the home were also observed. In conclusion, mouse allergen was prevalent among inner-city apartments, and the positive predictive value of self-reported frequent mouse sightings was high (90% for kitchens). However, high levels of mouse allergen were also found in many homes where mothers reported never seeing mice. JF - Environmental Health Perspectives AU - Chew, G L AU - Perzanowski AU - Miller, R L AU - Correa, J C AU - Hoepner, LA AU - Jusino, C M AU - Becker, M G AU - Kinney, P L AD - Mailman School of Public Health, Columbia University, 60 Haven Ave, B-1, New York, New York 10032-4206, USA, cg288@columbia.edu Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1348 EP - 1351 PB - NIH, Government Printing Office VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - distribution KW - mice KW - Toxicology Abstracts KW - X 24240:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18824439?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Distribution+and+Determinants+of+Mouse+Allergen+Exposure+in+Low-Income+New+York+City+Apartments&rft.au=Chew%2C+G+L%3BPerzanowski%3BMiller%2C+R+L%3BCorrea%2C+J+C%3BHoepner%2C+LA%3BJusino%2C+C+M%3BBecker%2C+M+G%3BKinney%2C+P+L&rft.aulast=Chew&rft.aufirst=G&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1348&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6124 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.6124 ER - TY - JOUR T1 - Neurologic Outcomes of Toxic Oil Syndrome Patients 18 Years after the Epidemic AN - 18823893; 5711826 AB - Toxic oil syndrome (TOS) resulted from consumption of rapeseed oil denatured with 2% aniline and affected more than 20,000 persons. Eighteen years after the epidemic, many patients continue to report neurologic symptoms that are difficult to evaluate using conventional techniques. We conducted an epidemiologic study to determine whether an exposure to toxic oil 18 years ago was associated with current adverse neurobehavioral effects. We studied a case group of 80 adults exposed to toxic oil 18 years ago and a referent group of 79 adult age- and sex-frequency-matched unexposed subjects. We interviewed subjects for demographics, health status, exposures to neurotoxicants, and responses to the Kaufman Brief Intelligence Test (K-BIT), Programa Integrado de Exploration Neuropsicologica (PIEN), and Goldberg depression questionnaires and administered quantitative neurobehavioral and neurophysiologic tests by computer or trained nurses. The groups did not differ with respect to educational background or other critical variables. We examined associations between case and referent groups and the neurobehavioral and neurophysiologic outcomes of interest. Decreased distal strength of the dominant and nondominant hands and increased vibrotactile thresholds of the fingers and toes were significantly associated with exposure to toxic oil. Finger tapping, simple reaction time latency, sequence B latency, symbol digit latency, and auditory digit span were also significantly associated with exposure. Case subjects also had statistically significantly more neuropsychologic symptoms compared with referents. Using quantitative neurologic tests, we found significant adverse central and peripheral neurologic effects in a group of TOS patients 18 years after exposure to toxic oil when compared with a nonexposed referent group. These effects were not documented by standard clinical examination and were found more frequently in women. JF - Environmental Health Perspectives AU - Posada de la Paz, M AU - Philen, R M AU - Gerr, F AU - Letz, R AU - Ferrari Arroyo, MJ AU - Vela, L AU - Izquierdo, M AU - Arribas, C M AU - Borda, IA AU - Ramos, A AU - Mora, C AU - Matesanz, G AU - Roldan, M T AU - Pareja, J AD - Instituto de Salud Carlos III, Centro de Investigacion sobre el Sindrome del Aceite Toxico y Enfermedades Raras, Sinesio Delgado 6, 28029 Madrid, Spain, mposada@isciii.es Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1326 EP - 1334 PB - NIH, Government Printing Office VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - man KW - rape seed oil KW - toxic oil syndrome KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - X 24120:Food, additives & contaminants KW - H 14000:Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18823893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Neurologic+Outcomes+of+Toxic+Oil+Syndrome+Patients+18+Years+after+the+Epidemic&rft.au=Posada+de+la+Paz%2C+M%3BPhilen%2C+R+M%3BGerr%2C+F%3BLetz%2C+R%3BFerrari+Arroyo%2C+MJ%3BVela%2C+L%3BIzquierdo%2C+M%3BArribas%2C+C+M%3BBorda%2C+IA%3BRamos%2C+A%3BMora%2C+C%3BMatesanz%2C+G%3BRoldan%2C+M+T%3BPareja%2C+J&rft.aulast=Posada+de+la+Paz&rft.aufirst=M&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1326&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6098 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.6098 ER - TY - JOUR T1 - A promoter derived from taro bacilliform badnavirus drives strong expression in transgenic banana and tobacco plants AN - 18809152; 5696867 AB - Taro bacilliform virus (TaBV) is a pararetrovirus of the genus Badnavirus which infects the monocotyledonous plant, taro (Colocasia esculenta). A region of the TaBV genome spanning nucleotides 6,281 to 12 (T1200), including the 3 end of open reading frame 3 (ORF 3) and the intergenic region to the end of the tRNA super(met)-binding site, was tested for promoter activity along with four different 5 deletion fragments (T600, T500, T250 and T100). In transient assays, only the T1200, T600, T500 fragments were shown to have promoter activity in taro leaf, banana suspension cells and tobacco callus. When these three promoters were evaluated in stably transformed, in vitro-grown transgenic banana and tobacco plants, all were found to drive near-constitutive expression of either the green fluorescent protein or beta -glucuronidase (GUS) reporter gene in the stem (or pseudostem), leaves and roots, with strongest expression observed in the vascular tissue. In transgenic banana leaves, the T600 promoter directed four-fold greater GUS activity than that of the T1200, T500 and the maize polyubiquitin-1 promoters. In transgenic tobacco leaves, the levels of GUS expression directed by the three promoters was between four- and ten-fold lower than that of the double Cauliflower mosaic virus 35S promoter. These results indicate that the TaBV-derived promoters may be useful for the high-level constitutive expression of transgenes in either monocotyledonous or dicotyledonous species. JF - Plant Cell Reports AU - Yang, I C AU - Iommarini, J P AU - Becker, D K AU - Hafner, G J AU - Dale, J L AU - Harding, R M AD - Centre for Molecular Biotechnology, Queensland University of Technology, GPO Box 2434, 4001, Brisbane, Australia Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1199 EP - 1206 PB - Springer-Verlag, [URL:http://link.springer.de/link/service/journals/00299/bibs/3021 012/30211199.htm] VL - 21 IS - 12 SN - 0721-7714, 0721-7714 KW - banana KW - taro KW - tobacco KW - transgenes KW - Biotechnology and Bioengineering Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Agricultural and Environmental Biotechnology Abstracts; Bioengineering Abstracts KW - W2 32065:Plants KW - W 30965:Miscellaneous, Reviews KW - N 14551:Virus & phage infections KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18809152?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Cell+Reports&rft.atitle=A+promoter+derived+from+taro+bacilliform+badnavirus+drives+strong+expression+in+transgenic+banana+and+tobacco+plants&rft.au=Yang%2C+I+C%3BIommarini%2C+J+P%3BBecker%2C+D+K%3BHafner%2C+G+J%3BDale%2C+J+L%3BHarding%2C+R+M&rft.aulast=Yang&rft.aufirst=I&rft.date=2003-08-01&rft.volume=21&rft.issue=12&rft.spage=1199&rft.isbn=&rft.btitle=&rft.title=Plant+Cell+Reports&rft.issn=07217714&rft_id=info:doi/10.1007%2Fs00299-003-0621-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1007/s00299-003-0621-x ER - TY - JOUR T1 - Antigen-Specific Immunoglobulin A Antibodies Secreted from Circulating B Cells Are an Effective Marker for Recent Local Immune Responses in Patients with Cholera: Comparison to Antibody-Secreting Cell Responses and Other Immunological Markers AN - 18796641; 5675854 AB - Gut-derived lymphocytes transiently migrate through the peripheral circulation before homing back to mucosal sites and can be detected using an ELISPOT-based antibody secreting cell (ASC) assay. Alternatively, transiently circulating lymphocytes may be cultured in vitro, and culture supernatants may be assayed for antigen-specific responses (antibody in lymphocyte supernatant (ALS) assay). The ALS assay has not been validated extensively in natural mucosal infection, nor has the ALS response been compared to the ASC assay and other cholera-specific immunological responses. Accordingly, we examined immune responses in 30 adult patients with acute cholera in Bangladesh, compared with 10 healthy controls, measuring ALS-immunoglobulin A (IgA), ASC-IgA, and serum and fecal IgA responses to two potent Vibrio cholerae immunogens, the nontoxic B subunit of cholera toxin (CtxB) and lipopolysaccharide (LPS) and a weaker V. cholerae immunogen, the mannose-sensitive hemagglutinin (MSHA). We found significant increases of anti-CtxB, anti-LPS, and anti-MSHA IgA in supernatants of lymphocytes cultured 7 days after onset of cholera using the ALS assay. We found that ALS and ASC responses correlated extremely well; both had comparable sensitivities as the vibriocidal responses, and both procedures were more sensitive than fecal IgA measurements. An advantage of the ALS assay for studying mucosal immune responses is the ability to freeze antibodies in supernatants for subsequent evaluation; like the ASC assay, the ALS assay can distinguish recent from remote mucosal infection, a distinction that may be difficult to make in endemic settings using other procedures. JF - Infection and Immunity AU - Qadri, F AU - Ryan, E T AU - Faruque, ASG AU - Ahmed, F AU - Khan, AI AU - Islam, M M AU - Akramuzzaman, S M AU - Sack, D AU - Calderwood, S B AD - Laboratory Sciences Division, ICDDR,B, GPO Box 128, Dhaka 1000, Bangladesh, fqadri@icddrb.org Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 4808 EP - 4814 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 71 IS - 8 SN - 0019-9567, 0019-9567 KW - CtxB protein KW - lipopolysaccharides KW - man KW - Immunology Abstracts; Microbiology Abstracts B: Bacteriology KW - F 06801:Bacteria KW - J 02833:Immune response and immune mechanisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18796641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+and+Immunity&rft.atitle=Antigen-Specific+Immunoglobulin+A+Antibodies+Secreted+from+Circulating+B+Cells+Are+an+Effective+Marker+for+Recent+Local+Immune+Responses+in+Patients+with+Cholera%3A+Comparison+to+Antibody-Secreting+Cell+Responses+and+Other+Immunological+Markers&rft.au=Qadri%2C+F%3BRyan%2C+E+T%3BFaruque%2C+ASG%3BAhmed%2C+F%3BKhan%2C+AI%3BIslam%2C+M+M%3BAkramuzzaman%2C+S+M%3BSack%2C+D%3BCalderwood%2C+S+B&rft.aulast=Qadri&rft.aufirst=F&rft.date=2003-08-01&rft.volume=71&rft.issue=8&rft.spage=4808&rft.isbn=&rft.btitle=&rft.title=Infection+and+Immunity&rft.issn=00199567&rft_id=info:doi/10.1128%2FIAI.71.8.4808-4814.2003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1128/IAI.71.8.4808-4814.2003 ER - TY - JOUR T1 - Low Birth Weight and Residential Proximity to PCB-Contaminated Waste Sites AN - 16160536; 5711830 AB - Previous investigations have shown that women exposed to polychlorinated biphenyls (PCBs) are at increased risk of giving birth to an infant with low birth weight (< 2,500 g), and that this relationship is stronger for male than for female infants. We have tested the hypothesis that residents in a zip code that contains a PCB hazardous waste site or abuts a body of water contaminated with PCBs are at increased risk of giving birth to a low-birth-weight baby. We used the birth registry of the New York State Vital Statistics to identify all births between 1994 and 2000 in New York State except for New York City. This registry provides information on the infant, mother, and father together with the zip code of the mother's residence. The 865 state Superfund sites, the 86 National Priority List sites, and the six Areas of Concern in New York were characterized regarding whether or not they contain PCBs as a major contaminant. We identified 187 zip codes containing or abutting PCB-contaminated sites, and these zip codes were the residences of 24.5% of the 945,077 births. The birth weight in the PCB zip codes was on average 21.6 g less than in other zip codes (p < 0.001). Because there are many other risk factors for low birth weight, we have adjusted for these using a logistic regression model for these confounders. After adjusting for sex of the infant, mother's age, race, weight, height, education, income, marital status, and smoking, there was still a statistically significant 6% increased risk of giving birth to a male infant of low birth weight. These observations support the hypothesis that living in a zip code near a PCB-contaminated site poses a risk of exposure and giving birth to an infant of low birth weight. JF - Environmental Health Perspectives AU - Baibergenova, A AU - Kudyakov, R AU - Zdeb, M AU - Carpenter, DO AD - School of Public Health, University at Albany, One University Place, B242, Rensselaer, NY 12144-3456, USA, Carpent@uamail.albany.edu Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1352 EP - 1357 PB - NIH, Government Printing Office VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - birth weight KW - low-birth-weight KW - man KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts; Pollution Abstracts KW - Risk assessment KW - Birth weight KW - Houses KW - Contamination KW - Superfund KW - Statistical analysis KW - Environmental health KW - USA, New York KW - Low-birth-weight KW - Waste disposal sites KW - Reproduction KW - Neonates KW - PCB compounds KW - Hazardous wastes KW - PCB KW - X 24156:Environmental impact KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16160536?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Low+Birth+Weight+and+Residential+Proximity+to+PCB-Contaminated+Waste+Sites&rft.au=Baibergenova%2C+A%3BKudyakov%2C+R%3BZdeb%2C+M%3BCarpenter%2C+DO&rft.aulast=Baibergenova&rft.aufirst=A&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1352&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6053 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2003-10-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Birth weight; Houses; Low-birth-weight; Contamination; Waste disposal sites; PCB; Risk assessment; Superfund; Statistical analysis; Environmental health; Reproduction; Neonates; PCB compounds; Hazardous wastes; USA, New York DO - http://dx.doi.org/10.1289/ehp.6053 ER - TY - JOUR T1 - Amyotrophic Lateral Sclerosis, Lead, and Genetic Susceptibility: Polymorphisms in the delta -Aminolevulinic Acid Dehydratase and Vitamin D Receptor Genes AN - 14668297; 10648347 AB - Data from a casenormal study conducted in New England over the period 199396 were used to investigate the associations of amyotrophic lateral sclerosis (ALS) with polymorphisms in the delta -aminolevulinic acid dehydratase (ALAD) and vitamin D receptor (VDR) genes and the influence of genotype on the previously observed association of ALS with lead exposure. Blood and bone Pb concentrations were measured, and DNA was isolated and genotyped. The ALAD 2 allele and a previously unidentified polymorphism at an MspI site in intron 2 of ALAD, denoted ALAD I2-2, were found to be associated with decreased bone Pb levels, but not with blood Pb levels. The VDR B allele showed no relationship to blood or bone Pb levels or to ALS risk. The results suggested that ALAD 2 alters the toxicokinetics of Pb, promoting retention of Pb in blood and migration of Pb from bone to blood. ALAD 2 appeared to be associated with an increase and ALAD I2-2 with a decrease in risk of ALS. JF - Environmental Health Perspectives AU - Kamel, Freya AU - Umbach, David M AU - Lehman, Teresa A AU - Park, Lawrence P AU - Munsat, Theodore L AU - Shefner, Jeremy M AU - Sandler, Dale P Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1335 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DISEASES AND DISORDERS KW - LEAD KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14668297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Amyotrophic+Lateral+Sclerosis%2C+Lead%2C+and+Genetic+Susceptibility%3A+Polymorphisms+in+the+delta+-Aminolevulinic+Acid+Dehydratase+and+Vitamin+D+Receptor+Genes&rft.au=Kamel%2C+Freya%3BUmbach%2C+David+M%3BLehman%2C+Teresa+A%3BPark%2C+Lawrence+P%3BMunsat%2C+Theodore+L%3BShefner%2C+Jeremy+M%3BSandler%2C+Dale+P&rft.aulast=Kamel&rft.aufirst=Freya&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1335&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; LEAD; GENETICS, HUMAN ER - TY - JOUR T1 - Gene Expression of Inflammatory Molecules in Circulating Lymphocytes from Arsenic-Exposed Human Subjects AN - 14667511; 10648517 AB - Taiwanese subjects identified as consumers of arsenic-tainted well water were used to identify gene expression changes in peripheral blood lymphocytes due to As exposure. cDNA microarray technology was applied to compare the gene expression profiles of peripheral blood lymphocytes from individuals of low-, intermediate-, and high-exposure groups. Alteration in expression level of several genes involved in inflammation exhibited a positive correlation with As concentration in whole blood, but in some study genes, a doseresponse relationship between transcription level and As exposure was not observed. However, a significant correlation was found for chemokine C-C motif 2/monocyte chemotactic protein-1 with As exposure. JF - Environmental Health Perspectives AU - Wu, Meei-Maan AU - Chiou, Hung-Yi AU - Ho, I-Ching AU - Chen, Chien-Jen AU - Lee, Te-Chang Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1429 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - LYMPHOCYTES KW - TAIWAN KW - BLOOD ANALYSIS KW - DOSE RESPONSE PROFILES KW - ARSENIC KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14667511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Gene+Expression+of+Inflammatory+Molecules+in+Circulating+Lymphocytes+from+Arsenic-Exposed+Human+Subjects&rft.au=Wu%2C+Meei-Maan%3BChiou%2C+Hung-Yi%3BHo%2C+I-Ching%3BChen%2C+Chien-Jen%3BLee%2C+Te-Chang&rft.aulast=Wu&rft.aufirst=Meei-Maan&rft.date=2003-08-01&rft.volume=111&rft.issue=11&rft.spage=1429&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - LYMPHOCYTES; BLOOD ANALYSIS; TAIWAN; DOSE RESPONSE PROFILES; ARSENIC; GENETICS, HUMAN ER - TY - JOUR T1 - Use of QSARs in International Decision-Making Frameworks to Predict Health Effects of Chemical Substances AN - 14666870; 10648354 AB - The international regulatory use of quantitative structureactivity relationships (QSARs) to predict the health effects of chemical substances is reviewed, describing their use by a number of regulatory agencies to prioritize chemicals for testing and to fill data gaps in risk assessment data sets. The focus is on the European Union and North America. Expert systems developed to predict chemical toxicity are outlined, including TOPKAT, the computer-automated structure evaluation methodology, deductive estimation of risk from existing knowledge for Windows, HazardExpert, the optimized approach based on structural indices set, and the substructure-based computerized chemical selection expert system. Use of selected expert systems to predict acute and chronic toxicity, mutagenicity, carcinogenicity, reproductive/developmental toxicity, eye irritation, skin sensitization, and percutaneous absorption, and to assess the human health effects of high-production-volume chemicals is described. JF - Environmental Health Perspectives AU - Cronin, Mark TD AU - Jaworska, Joanna S AU - Walker, John D AU - Comber, Michael HI AU - Watts, Christopher D AU - Worth, Andrew P Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1391 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - EXPERT SYSTEMS KW - TOXIC SUBSTANCES KW - REGULATORY COMMISSIONS, FEDERAL KW - DECISION MAKING KW - REGULATORY COMMISSIONS, NON US KW - PUBLIC HEALTH KW - QUANTITATIVE STRUCTURE-ACTIVITY RELATION KW - POLLUTANT FATE KW - RISK ASSESSMENT KW - CHEMICAL ANALYSIS KW - EUROPEAN UNION KW - NORTH AMERICA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666870?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Use+of+QSARs+in+International+Decision-Making+Frameworks+to+Predict+Health+Effects+of+Chemical+Substances&rft.au=Cronin%2C+Mark+TD%3BJaworska%2C+Joanna+S%3BWalker%2C+John+D%3BComber%2C+Michael+HI%3BWatts%2C+Christopher+D%3BWorth%2C+Andrew+P&rft.aulast=Cronin&rft.aufirst=Mark&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1391&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; EXPERT SYSTEMS; TOXIC SUBSTANCES; REGULATORY COMMISSIONS, FEDERAL; CHEMICAL ANALYSIS; NORTH AMERICA; EUROPEAN UNION; DECISION MAKING; REGULATORY COMMISSIONS, NON US; POLLUTANT FATE; PUBLIC HEALTH; QUANTITATIVE STRUCTURE-ACTIVITY RELATION ER - TY - JOUR T1 - Environmental Threats to Children's Health in Southeast Asia and the Western Pacific AN - 14666841; 10648348 JF - Environmental Health Perspectives AU - Suk, William A AU - Ruchirawat, Kuhnying Mathuros AU - Balakrishnan, Kalpana AU - Berger, Martha AU - Carpenter, David AU - Damstra, Terri AU - Pronczuk de Garbino, Jenny Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1340 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - OCEANIA KW - CLIMATE CHANGE KW - RISK ASSESSMENT KW - PATHOLOGY, CHILDREN KW - AIR POLLUTION, INDOOR KW - SOUTHEAST ASIA KW - LEAD KW - PESTICIDE EXPOSURE KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666841?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Environmental+Threats+to+Children%27s+Health+in+Southeast+Asia+and+the+Western+Pacific&rft.au=Suk%2C+William+A%3BRuchirawat%2C+Kuhnying+Mathuros%3BBalakrishnan%2C+Kalpana%3BBerger%2C+Martha%3BCarpenter%2C+David%3BDamstra%2C+Terri%3BPronczuk+de+Garbino%2C+Jenny&rft.aulast=Suk&rft.aufirst=William&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1340&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; OCEANIA; PATHOLOGY, CHILDREN; AIR POLLUTION, INDOOR; SOUTHEAST ASIA; LEAD; PESTICIDE EXPOSURE; CLIMATE CHANGE; MERCURY ER - TY - JOUR T1 - Exploring Bias in a Generalized Additive Model for Spatial Air Pollution Data AN - 14666773; 10648339 AB - Results are presented from two simulation studies designed to explore the impact of concurvity on a particular data set gleaned from the literature: the second stage of a two-stage analysis relating air pollution to mortality. In the first stage, survival data from a cohort of more than 500,000 subjects in 144 US metropolitan areas were fit, via a Cox proportional hazards model, to a collection of both individual- and community-level variables. The second stage employed a spatial generalized additive model to relate mortality to air pollution by modeling the log-relative risks as the sum of a nonparametric function of location and a linear function of airborne sulfate particle concentration. The results suggest that, even with stringent convergence criteria, increased concurvity in the data used to fit the semiparametric spatial generalized additive model led directly to increased downward bias in the estimated standard error of the fitted linear parameter. The result was similar for both the S-Plus standard error estimate and the asymptotically unbiased alternative estimate. JF - Environmental Health Perspectives AU - Ramsay, Timothy AU - Burnett, Richard AU - Krewski, Daniel Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1283 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MATHEMATIC MODELS, AIR KW - AIR POLLUTION EFFECTS KW - QUANTITATIVE ANALYSIS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666773?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Exploring+Bias+in+a+Generalized+Additive+Model+for+Spatial+Air+Pollution+Data&rft.au=Ramsay%2C+Timothy%3BBurnett%2C+Richard%3BKrewski%2C+Daniel&rft.aulast=Ramsay&rft.aufirst=Timothy&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1283&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MATHEMATIC MODELS, AIR; AIR POLLUTION EFFECTS; QUANTITATIVE ANALYSIS; PARTICULATES ER - TY - JOUR T1 - Low-Dose Exposure to Inorganic Mercury Accelerates Disease and Mortality in Acquired Murine Lupus AN - 14666762; 10648337 JF - Environmental Health Perspectives AU - Via, Charles S AU - Nguyen, Phuong AU - Niculescu, Florin AU - Papadimitriou, John AU - Hoover, Dennis AU - Silbergeld, Ellen K Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1273 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - IMMUNOTOXICITY KW - DISEASES AND DISORDERS KW - MERCURY KW - IMMUNE RESPONSE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666762?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Low-Dose+Exposure+to+Inorganic+Mercury+Accelerates+Disease+and+Mortality+in+Acquired+Murine+Lupus&rft.au=Via%2C+Charles+S%3BNguyen%2C+Phuong%3BNiculescu%2C+Florin%3BPapadimitriou%2C+John%3BHoover%2C+Dennis%3BSilbergeld%2C+Ellen+K&rft.aulast=Via&rft.aufirst=Charles&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1273&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - IMMUNOTOXICITY; DISEASES AND DISORDERS; MERCURY; IMMUNE RESPONSE ER - TY - JOUR T1 - Summary of a Workshop on Regulatory Acceptance of (Q)SARs for Human Health and Environmental Endpoints AN - 14666237; 10648351 AB - Quantitative structureactivity relationships [(Q)SARs] are simplified mathematical representations of complex chemicalbiological interactions, which have the potential to save time and money and minimize the use of animal testing. A summary is provided of the findings from a 3-d workshop entitled Regulatory Acceptance of (Q)SARs for Human Health and Environmental Endpoints", which addressed acceptability criteria for (Q)SARs, future applications, and the management of accepted (Q)SAR models. The recommendations proposed at the workshop regarding the need for acceptability criteria and validation if (Q)SAR models for the purpose of regulatory applications are presented. JF - Environmental Health Perspectives AU - Jaworska, Joanna S AU - Comber, M AU - Auer, C AU - Van Leeuwen, CJ Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1358 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DATA, CHEMICAL KW - QUANTITATIVE STRUCTURE-ACTIVITY RELATION KW - MATHEMATIC MODELS, CHEMICAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Summary+of+a+Workshop+on+Regulatory+Acceptance+of+%28Q%29SARs+for+Human+Health+and+Environmental+Endpoints&rft.au=Jaworska%2C+Joanna+S%3BComber%2C+M%3BAuer%2C+C%3BVan+Leeuwen%2C+CJ&rft.aulast=Jaworska&rft.aufirst=Joanna&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1358&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DATA, CHEMICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATION; MATHEMATIC MODELS, CHEMICAL ER - TY - JOUR T1 - Genetic Variation in Genes Associated with Arsenic Metabolism: Glutathione S-Transferase Omega 1-1 and Purine Nucleoside Phosphorylase Polymorphisms in European and Indigenous Americans AN - 14665164; 10648516 AB - The first polymorphic screening of two genes involved in arsenic biotransformation is presented. The products of the genes, human purine nucleoside phosphorylase (hNP) and human glutathione S-transferase omega 1-1 (hGSTO1-1), function as arsenate reductase and monomethylarsonic acid reductase, respectively. Two populations of subjects, Europeans and indigenous Americans, were used to develop the catalog. The analysis of hGSTO1-1 revealed a higher degree of predicted amino acid polymorphism than observed in hNP. In hNP, only 17% of polymorphisms occurring in exons were nonsynonymous, while 64% of exon polymorphisms in hGSTO1-1 were nonsynonymous. For the indigenous American group, only one polymorphism, 668, was necessary to define all common haplotypes, while in the European group, two polymorphisms, 668 and one from the cluster of seven linked polymorphisms, were necessary to define all common haplotypes. JF - Environmental Health Perspectives AU - Yu, Lizhi AU - Kalla, Kelly AU - Guthrie, Erin AU - Vidrine, Amy AU - Klimecki, Walter T Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1421 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ENZYMES KW - ARSENIC KW - METABOLIC ACTIVATION KW - RACIAL COMPARISONS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14665164?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Genetic+Variation+in+Genes+Associated+with+Arsenic+Metabolism%3A+Glutathione+S-Transferase+Omega+1-1+and+Purine+Nucleoside+Phosphorylase+Polymorphisms+in+European+and+Indigenous+Americans&rft.au=Yu%2C+Lizhi%3BKalla%2C+Kelly%3BGuthrie%2C+Erin%3BVidrine%2C+Amy%3BKlimecki%2C+Walter+T&rft.aulast=Yu&rft.aufirst=Lizhi&rft.date=2003-08-01&rft.volume=111&rft.issue=11&rft.spage=1421&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENZYMES; METABOLIC ACTIVATION; ARSENIC; RACIAL COMPARISONS; GENETICS, HUMAN ER - TY - JOUR T1 - Effect of Polychlorinated Biphenyls on Estrogen Receptor- beta Expression in the Anteroventral Periventricular Nucleus AN - 14664325; 10648338 AB - Timed-pregnant female SpragueDawley rats were used to identify neurobiologic targets for actions of Aroclor 1221 and to correlate the changes in the targets with other effects of the commercial PCB mixture on reproductive and somatic growth and development. The focus was on the estrogen receptor- beta . The studies were performed on the anteroventral periventricular nucleus, a sexually dimorphic region of the brain involved critically in female reproductive physiology, and results were compared with those observed in the supraoptic nucleus, a hypothalamic nucleus that expresses estrogen receptor- beta , but is implicated more strongly in the control of water and electrolyte balance and maternal behavior. The injections were given on gestational day 16 and on postnatal days 2 and 4. Results showed that neonatal treatment with a low and ecologically relevant dose of Aroclor 1221 caused a substantial down-regulation of numbers of estrogen receptor- beta -positive cells in the anteroventral periventricular nucleus, but had no effect on the supraoptic nucleus. No significant effects of Aroclor 1221 were noted on the timing of puberty, first estrus, reproductive tract weight, and estrous cyclicity, although the trends were consistent with the effects of exogenous estrogens given during development that have been observed in other studies. JF - Environmental Health Perspectives AU - Salama, Jacklyn AU - Chakraborty, Tandra R AU - Ng, Laurie AU - Gore, Andrea C Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1278 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AROCLOR KW - POLYCHLORINATED BIPHENYLS KW - HORMONAL EFFECTS KW - REPRODUCTION, ANIMAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14664325?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+of+Polychlorinated+Biphenyls+on+Estrogen+Receptor-+beta+Expression+in+the+Anteroventral+Periventricular+Nucleus&rft.au=Salama%2C+Jacklyn%3BChakraborty%2C+Tandra+R%3BNg%2C+Laurie%3BGore%2C+Andrea+C&rft.aulast=Salama&rft.aufirst=Jacklyn&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1278&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AROCLOR; POLYCHLORINATED BIPHENYLS; HORMONAL EFFECTS; REPRODUCTION, ANIMAL ER - TY - JOUR T1 - Mechanisms of Benzene-Induced Hematotoxicity and Leukemogenicity: cDNA Microarray Analyses Using Mouse Bone Marrow Tissue AN - 14663950; 10648515 AB - Bone marrow tissue is a major target organ of benzene and is an active hemopoietic system in which various counterbalanced genes are organized through their network interactions that maintain cellularenvironmental homeostasis. Results are presented from a study in which changes in DNA expression were assessed during and after benzene exposure. The analyses were conducted using cDNA microarray analyses in C57BL/6, wild-type, and p53-knockout mice. The mice were exposed to 300 ppm benzene for 6 h/d, 5 d/week, for two weeks. Bone marrow cell collection for RNA extraction, preparation of total RNA and poly(A) super(+) RNA, and microarray preparation are detailed. Results reveal that p53-knockout mice were not resistant to benzene-induced toxic effects, showing comparable dynamic protective responses to C57BL/6 and wild-type mice at the gene functional level. The effects of benzene on bone marrow cells are described, based on multigene expression profiles that explain the high incidence and early onset of hemopoietic neoplasia that were observed clearly in exposed p53 hetero- and homozygous knockout mice. JF - Environmental Health Perspectives AU - Yoon, Byung-Il AU - Li, Guang-Xun AU - Kitada, Kunio AU - Kawasaki, Yasushi AU - Igarashi, Katsuhide AU - Kodama, Yukio AU - Inoue, Tomoaki Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1411 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - BLOOD ANALYSIS KW - DNA KW - BENZENE KW - TOXICOLOGY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663950?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Mechanisms+of+Benzene-Induced+Hematotoxicity+and+Leukemogenicity%3A+cDNA+Microarray+Analyses+Using+Mouse+Bone+Marrow+Tissue&rft.au=Yoon%2C+Byung-Il%3BLi%2C+Guang-Xun%3BKitada%2C+Kunio%3BKawasaki%2C+Yasushi%3BIgarashi%2C+Katsuhide%3BKodama%2C+Yukio%3BInoue%2C+Tomoaki&rft.aulast=Yoon&rft.aufirst=Byung-Il&rft.date=2003-08-01&rft.volume=111&rft.issue=11&rft.spage=1411&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; GENETICS, ANIMAL; DNA; BENZENE; TOXICOLOGY ER - TY - JOUR T1 - Increased Influence of Genetic Variation on PON1 Activity in Neonates AN - 14663889; 10648514 AB - After activation of chlorpyrifos and other organophosphates to the reactive oxon, the oxon may be detoxified by paraoxonase-1 (PON1) before it has the change to inactivate acetylcholinesterase in the peripheral nervous system and central nervous system. PON1 also functions to cleave oxidized lipids in low- and high-density lipid liproproteins. The PON1 gene has been fully characterized, and studies have shown that the toxicity of chlorpyrifos is related inversely to serum PON1 activity. Using maternal and cord blood, a systematic study was conducted of the origin and extent of variation in PON1 activities in three racial/ethnic groups comprising the majority of many inner-city populations: Caucasians, African Americans, and Caribbean Hispanics. Single nucleotide polymorphism frequencies were obtained for the five common PON1 polymorphisms and for one common PON2 polymorphism. The allele frequencies among Caribbean Hispanics fell between the values for Caucasians and African Americans, with frequencies consistent with similar Caucasian and African-American deviation. For each race/ethnicity, neonates had much lower PON1 activities than the adults, with the mean PON1 activity in maternal blood 4.6, 3.6 and 2.6 times greater than the mean PON1 activity in cord flood for Caucasians, Caribbean Hispanics, and African Americans, respectively. The important alleles affecting PON1 activity are described. JF - Environmental Health Perspectives AU - Chen, Jia AU - Kumar, Madhu AU - Chan, Wendy AU - Berkowitz, Gertrud AU - Wetmur, James G Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1403 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ENZYME ACTIVITY KW - DETOXIFICATION KW - REPRODUCTION, HUMAN KW - CHLORPYRIFOS KW - RACIAL COMPARISONS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663889?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Increased+Influence+of+Genetic+Variation+on+PON1+Activity+in+Neonates&rft.au=Chen%2C+Jia%3BKumar%2C+Madhu%3BChan%2C+Wendy%3BBerkowitz%2C+Gertrud%3BWetmur%2C+James+G&rft.aulast=Chen&rft.aufirst=Jia&rft.date=2003-08-01&rft.volume=111&rft.issue=11&rft.spage=1403&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENZYME ACTIVITY; REPRODUCTION, HUMAN; CHLORPYRIFOS; DETOXIFICATION; RACIAL COMPARISONS; GENETICS, HUMAN ER - TY - JOUR T1 - Methods for Reliability and Uncertainty Assessment and for Applicability Evaluations of Classification- and Regression-Based QSARs AN - 14663659; 10648352 AB - Quantitative structureactivity relationships (QSARs) are being used increasingly by authorities and industries to assess the risks of chemicals released to the environment. A review is presented of QSARs, focusing on analogy models, the role of pattern recognition in QSARs, conditions for applicability and validity of QSARs, multiple linear regression and other modeling techniques, and methods for assessing and enhancing QSAR model reliability, interpretability, and predictive power. JF - Environmental Health Perspectives AU - Eriksson, Lennart AU - Jaworska, Joanna AU - Worth, Andrew P AU - Cronin, Mark TD AU - McDowell, Robert M AU - Gramatica, Paola Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1361 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DATA, CHEMICAL KW - QUANTITATIVE STRUCTURE-ACTIVITY RELATION KW - MATHEMATIC MODELS, CHEMICAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663659?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Methods+for+Reliability+and+Uncertainty+Assessment+and+for+Applicability+Evaluations+of+Classification-+and+Regression-Based+QSARs&rft.au=Eriksson%2C+Lennart%3BJaworska%2C+Joanna%3BWorth%2C+Andrew+P%3BCronin%2C+Mark+TD%3BMcDowell%2C+Robert+M%3BGramatica%2C+Paola&rft.aulast=Eriksson&rft.aufirst=Lennart&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1361&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DATA, CHEMICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATION; MATHEMATIC MODELS, CHEMICAL ER - TY - JOUR T1 - Assessment of Potential Risk Levels Associated with U.S. Environmental Protection Agency Reference Values AN - 14663614; 10648345 AB - EPA has been developing the benchmark dose (BMD), which is derived from modeling the exposureresponse data, as an alternative to the no-observed/lowest-observed adverse effect levels as the point of departure for noncancer risk assessments. The BMD is the dose corresponding to a specified level of increased response compared with background. The EPA Integrated Risk Information Systems database was searched to identify the chemicals for which current regulatory reference values had relied on BMD modeling, and the equivalent risk levels expected from hypothetical human exposures were estimated at established reference dose and reference concentration values using the BMD doseresponse information to investigate whether the levels represent negligible risks. Results showed that 24% of reference values corresponded to estimated risk levels greater than 1 in 1000. The central estimate of the BMD instead of the lower bound estimate as the point of departure resulted in a one- to threefold difference in the risk estimates. JF - Environmental Health Perspectives AU - Castorina, Rosemary AU - Woodruff, Tracey J Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1318 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - DOSE RESPONSE PROFILES KW - EPA, FEDERAL KW - CHEMICAL CONTAMINATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663614?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Potential+Risk+Levels+Associated+with+U.S.+Environmental+Protection+Agency+Reference+Values&rft.au=Castorina%2C+Rosemary%3BWoodruff%2C+Tracey+J&rft.aulast=Castorina&rft.aufirst=Rosemary&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1318&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DOSE RESPONSE PROFILES; EPA, FEDERAL; CHEMICAL CONTAMINATION ER - TY - JOUR T1 - Assessment of Dietary Exposure to Some Persistent Organic Pollutants in the Republic of Karakalpakstan for Uzbekistan AN - 14663259; 10648343 AB - In three towns in Karakalpakstan, Uzbekistan, where toxicologic investigations of human breast milk and maternal and cord blood had been conducted recently, 36 food samples were collected and analyzed for PCDDs, PCDFs, PCBs, and selected organochlorine and organophosphate pesticides. Elevated levels of hexachlorocyclohexanes, p,p'-DDE, and dioxins, especially TCDD, were found in the food samples, with highest levels found in foods with elevated lipid content such as sheep and chicken fat, eggs, and cottonseed oil. The dietary dioxin exposure for a typical Karakalpakstan resident was estimated to be almost three times higher than the level considered to be safe by WHO. JF - Environmental Health Perspectives AU - Muntean, Nigina AU - Jermini, Marco AU - Small, Ian AU - Falzon, Dennis AU - Furst, Peter AU - Migliorati, Giacomo AU - Scortichini, Giampiero Y1 - 2003/08// PY - 2003 DA - Aug 2003 SP - 1306 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - POLYCHLORINATED DIBENZODIOXINS KW - DIET KW - POLYCHLORINATED DIBENZOFURANS KW - ORGANOCHLORINE PESTICIDES KW - FOOD CONTAMINATION KW - ORGANOPHOSPHATE PESTICIDES KW - FOOD ANALYSIS KW - UZBEKISTAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663259?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Dietary+Exposure+to+Some+Persistent+Organic+Pollutants+in+the+Republic+of+Karakalpakstan+for+Uzbekistan&rft.au=Muntean%2C+Nigina%3BJermini%2C+Marco%3BSmall%2C+Ian%3BFalzon%2C+Dennis%3BFurst%2C+Peter%3BMigliorati%2C+Giacomo%3BScortichini%2C+Giampiero&rft.aulast=Muntean&rft.aufirst=Nigina&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1306&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ORGANOPHOSPHATE PESTICIDES; POLYCHLORINATED BIPHENYLS; POLYCHLORINATED DIBENZODIOXINS; FOOD ANALYSIS; DIET; ORGANOCHLORINE PESTICIDES; POLYCHLORINATED DIBENZOFURANS; FOOD CONTAMINATION; UZBEKISTAN ER - TY - GEN T1 - [Concerns about Security, Technology, and Surveillance Activities by Bush Administration; Handwritten] AN - 1679112728; SU00187 AB - Senator Rockefeller expresses concerns to Vice President Cheney regarding unspecified surveillance activities that "raise profound oversight issues." AU - United States. Congress. Senate. Select Committee on Intelligence AD - United States. Congress. Senate. Select Committee on Intelligence PY - 2003 SP - 2 KW - Cheney, Richard B. KW - Congressional oversight KW - Electronic surveillance KW - Information technology KW - Total Information Awareness Program KW - Poindexter, John M. KW - Hayden, Michael V. KW - Tenet, George J. KW - Roberts, Charles Patrick KW - Poindexter, John M. KW - Hayden, Michael V. KW - Tenet, George J. KW - Roberts, Charles Patrick UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679112728?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_su&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=%5BConcerns+about+Security%2C+Technology%2C+and+Surveillance+Activities+by+Bush+Administration%3B+Handwritten%5D&rft.au=United+States.+Congress.+Senate.+Select+Committee+on+Intelligence&rft.aulast=United+States.+Congress.+Senate.+Select+Committee+on+Intelligence&rft.aufirst=&rft.date=2003-07-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ L2 - http://www.epic.org. LA - English DB - Digital National Security Archive N1 - Name - United States. Congress. House. Permanent Select Committee on Intelligence N1 - Publication note - National Security Archive. Wiretap Debate Déjà Vu. Electronic Briefing Book 178, February 4, 2006, http://www2.gwu.edu/~nsarchiv/NSAEBB/NSAEBB178/ (previously published document) N1 - Analyte descriptor - NSA document type: Letter ; Location of original: Available [Online]: Electronic Privacy Information Center N1 - People - Hayden, Michael V.; Poindexter, John M.; Roberts, Charles Patrick; Tenet, George J. N1 - Last updated - 2015-12-14 ER - TY - JOUR T1 - Growth and stem form responses of plantation-grown Acacia melanoxylon (R. Br.) to form pruning and nurse-crop thinning AN - 17668012; 5657770 AB - This study investigated the feasibility of silvicultural intervention in Acacia melanoxylon (R. Br.) plantations grown with Pinus radiata (D. Don) nurse crops, to improve stem form and growth rate. The objective of the study was to evaluate silvicultural options for managing a nurse-crop to avoid suppression but improve stem form of A. melanoxylon. Using a 5-year-old A. melanoxylon-P. radiata plantation, various levels of form pruning of the A. melanoxylon were tested by removing prescribed proportions of leaf area from treatment trees. In addition, a range of thinning treatments was imposed on the nurse-crop. The effects of these treatments on A. melanoxylon growth rate, stem form, rate of crown development, and canopy light environment were assessed. Altering the canopy structure of the plantations by thinning the P. radiata nurse-crop had a positive effect on A. melanoxylon diameter growth. However, less desirable changes were also evident following thinning of the P. radiata, such as reduced height increment, loss of dominance and a greater incidence of large branches in A. melanoxylon trees. Appreciable changes in the light environment of the A. melanoxylon crowns occurred only after more than 50% of P. radiata trees were removed. Crowns of A. melanoxylon trees pruned of 50% of their foliage area took 12 months to recover to pre-pruning foliage area levels. Form pruning A. melanoxylon significantly reduced growth when 50% of foliage area was removed. Improvements in form by pruning were transient in nature, highlighting the need for on-going, low-intensity form pruning treatment to establish good stem form. The rapid deterioration in form after heavy thinning of the nurse-crop indicated the need to establish form before reducing nurse-crop competition. JF - Forest Ecology and Management AU - Medhurst, J L AU - Pinkard, E A AU - Beadle, CL AU - Worledge, D AD - Cooperative Research Centre for Sustainable Production Forestry, GPO Box 252-12, Hobart 7001, Tasmania, Australia, libby.pinkard@ffp.csiro.au Y1 - 2003/07/03/ PY - 2003 DA - 2003 Jul 03 SP - 183 EP - 193 VL - 179 IS - 1-3 SN - 0378-1127, 0378-1127 KW - Ecology Abstracts KW - D 04700:Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17668012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forest+Ecology+and+Management&rft.atitle=Growth+and+stem+form+responses+of+plantation-grown+Acacia+melanoxylon+%28R.+Br.%29+to+form+pruning+and+nurse-crop+thinning&rft.au=Medhurst%2C+J+L%3BPinkard%2C+E+A%3BBeadle%2C+CL%3BWorledge%2C+D&rft.aulast=Medhurst&rft.aufirst=J&rft.date=2003-07-03&rft.volume=179&rft.issue=1-3&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Forest+Ecology+and+Management&rft.issn=03781127&rft_id=info:doi/10.1016%2FS0378-1127%2802%2900521-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-08-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0378-1127(02)00521-2 ER - TY - JOUR T1 - The design of bells with harmonic overtones. AN - 85377037; pmid-12880061 AB - Musical bells have had limited application due to the presence of inharmonic partials in the lower part of their acoustic spectra. A series of bells has been designed that contains up to seven partial frequencies in the harmonic series beginning at the fundamental frequency. This was achieved by choosing geometries for finite-element analysis models in which as many purely circumferential bending modes as possible occurred at frequencies below any mode with an axial ring node. The bell models were then fine tuned using gradient projection method shape optimization and the resulting profiles were cast in silicon bronze. A range of bell geometries and timbres is analyzed using psycho-acoustic models and is discussed in relation to European carillon bells. JF - The Journal of the Acoustical Society of America AU - McLachlan, Neil AU - Nigjeh, Behzad Keramati AU - Hasell, Anton AD - Department of Aerospace Engineering, RMIT University, GPO Box 2476V, Melbourne 3001, Australia. neil@ausbell.com Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 505 EP - 511 VL - 114 IS - 1 SN - 0001-4966, 0001-4966 KW - National Library of Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85377037?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+the+Acoustical+Society+of+America&rft.atitle=The+design+of+bells+with+harmonic+overtones.&rft.au=McLachlan%2C+Neil%3BNigjeh%2C+Behzad+Keramati%3BHasell%2C+Anton&rft.aulast=McLachlan&rft.aufirst=Neil&rft.date=2003-07-01&rft.volume=114&rft.issue=1&rft.spage=505&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+the+Acoustical+Society+of+America&rft.issn=00014966&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - Stem cells and cardiovascular disease AN - 754557527; 13337545 AB - Several recent discoveries have shifted the paradigm that there is no potential for myocardial regeneration and have fueled enthusiasm for a new frontier in the treatment of cardiovascular disease--stem cells. Fundamental to this emerging field is the cumulative evidence that adult bone marrow stem cells can differentiate into a wide variety of cell types, including cardiac myocytes and endothelial cells. This phenomenon has been termed stem cell plasticity and is the basis for the explosive recent interest in stem cellubased therapies. Directed to cardiovascular disease, stem cell therapy holds the promise of replacing lost heart muscle and enhancing cardiovascular revascularization. Early evidence of the feasibility of stem cell therapy for cardiovascular disease came from a series of animal experiments demonstrating that adult stem cells could become cardiac muscle cells (myogenesis) and participate in the formation of new blood vessels (angiogenesis and vasculogenesis) in the heart after myocardial infarction. These findings have been rapidly translated to ongoing human trials, but many questions remain. This review focuses on the use of adult bone marrowuderived stem cells for the treatment of ischemic cardiovascular disease and will contrast how far we have come in a short time with how far we still need to go before stem cell therapy becomes routine in cardiovascular medicine. JF - Journal of Nuclear Cardiology AU - Abbott, JDawn AU - Giordano, Frank J AD - The Division of Cardiovascular Medicine, Boyer Center for Molecular Medicine, 436C, Yale University School of Medicine, 295 Congress Ave, 06520, New Haven, CT, frank.giordano@yale.edu Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 403 EP - 412 PB - Mosby, Inc., New York VL - 10 IS - 4 SN - 1071-3581, 1071-3581 KW - Biotechnology and Bioengineering Abstracts KW - myogenesis KW - Bone marrow KW - Angiogenesis KW - Cardiac muscle KW - Ischemia KW - cardiomyocytes KW - Plasticity KW - Myocardial infarction KW - Endothelial cells KW - Stem cells KW - Blood vessels KW - Regeneration KW - Cardiovascular diseases KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754557527?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Nuclear+Cardiology&rft.atitle=Stem+cells+and+cardiovascular+disease&rft.au=Abbott%2C+JDawn%3BGiordano%2C+Frank+J&rft.aulast=Abbott&rft.aufirst=JDawn&rft.date=2003-07-01&rft.volume=10&rft.issue=4&rft.spage=403&rft.isbn=&rft.btitle=&rft.title=Journal+of+Nuclear+Cardiology&rft.issn=10713581&rft_id=info:doi/10.1016%2FS1071-3581%2803%2900580-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - myogenesis; Angiogenesis; Bone marrow; Cardiac muscle; cardiomyocytes; Ischemia; Plasticity; Myocardial infarction; Endothelial cells; Stem cells; Blood vessels; Regeneration; Cardiovascular diseases DO - http://dx.doi.org/10.1016/S1071-3581(03)00580-4 ER - TY - JOUR T1 - Structural and functional evidence for the interaction of insulin-like growth factors (IGFs) and IGF binding proteins with vitronectin. AN - 73398328; 12810534 AB - Previous studies demonstrated that IGF-II binds directly to vitronectin (VN), whereas IGF-I binds poorly. However, binding of VN to integrins has been demonstrated to be essential for a range of IGF-I-stimulated biological effects, including IGF binding protein (IGFBP)-5 production, IGF type-1 receptor autophosphorylation, and cell migration. Thus, we hypothesized that a link between IGF-I and VN must occur and may be mediated through IGFBPs. This was tested using competitive binding assays with VN and (125)iodine-labeled IGFs in the absence and presence of IGFBPs. IGFBP-4, IGFBP-5, and nonglycosylated IGFBP-3 were shown to significantly enhance binding of IGF-I to VN, whereas IGFBP-2 and glycosylated IGFBP-3 had a smaller effect. Furthermore, binding studies with analogs indicate that glycosylation status and the heparin-binding domain of IGFBP-3 are important in this interaction. To examine the functional significance of IGFs binding to VN, cell migration in MCF7 cells was measured and found to be enhanced when VN was prebound to IGF-I in the presence of IGFBP-5. The effect required IGF:IGFBP:VN complex formation; this was demonstrated by use of a non-IGFBP-binding IGF-I analog. Together, these data indicate the importance of IGFBPs in modulating IGF-I binding to VN and that this binding has functional consequences in cells. JF - Endocrinology AU - Kricker, Jennifer A AU - Towne, Chris L AU - Firth, Sue M AU - Herington, Adrian C AU - Upton, Zee AD - Tissue BioRegeneration and Integration Program, School of Life Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia. j.kricker@qut.edu.au Y1 - 2003/07// PY - 2003 DA - July 2003 SP - 2807 EP - 2815 VL - 144 IS - 7 SN - 0013-7227, 0013-7227 KW - Insulin-Like Growth Factor Binding Protein 2 KW - 0 KW - Insulin-Like Growth Factor Binding Protein 3 KW - Insulin-Like Growth Factor Binding Protein 4 KW - Insulin-Like Growth Factor Binding Protein 5 KW - Insulin-Like Growth Factor Binding Proteins KW - Iodine Radioisotopes KW - Vitronectin KW - Insulin-Like Growth Factor I KW - 67763-96-6 KW - Insulin-Like Growth Factor II KW - 67763-97-7 KW - Abridged Index Medicus KW - Index Medicus KW - Drug Interactions KW - Insulin-Like Growth Factor Binding Protein 3 -- pharmacology KW - Humans KW - Breast Neoplasms KW - Glycosylation KW - Insulin-Like Growth Factor Binding Protein 5 -- metabolism KW - Insulin-Like Growth Factor Binding Protein 4 -- pharmacology KW - Insulin-Like Growth Factor Binding Protein 2 -- pharmacology KW - Tumor Cells, Cultured KW - Cell Movement -- physiology KW - Binding, Competitive KW - Insulin-Like Growth Factor Binding Protein 5 -- pharmacology KW - Cell Movement -- drug effects KW - Insulin-Like Growth Factor Binding Protein 2 -- metabolism KW - Insulin-Like Growth Factor Binding Protein 4 -- metabolism KW - Insulin-Like Growth Factor Binding Protein 3 -- metabolism KW - Vitronectin -- metabolism KW - Insulin-Like Growth Factor II -- analogs & derivatives KW - Insulin-Like Growth Factor I -- metabolism KW - Insulin-Like Growth Factor I -- analogs & derivatives KW - Insulin-Like Growth Factor II -- metabolism KW - Insulin-Like Growth Factor Binding Proteins -- metabolism KW - Insulin-Like Growth Factor I -- pharmacology KW - Insulin-Like Growth Factor II -- pharmacology KW - Insulin-Like Growth Factor Binding Proteins -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73398328?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Structural+and+functional+evidence+for+the+interaction+of+insulin-like+growth+factors+%28IGFs%29+and+IGF+binding+proteins+with+vitronectin.&rft.au=Kricker%2C+Jennifer+A%3BTowne%2C+Chris+L%3BFirth%2C+Sue+M%3BHerington%2C+Adrian+C%3BUpton%2C+Zee&rft.aulast=Kricker&rft.aufirst=Jennifer&rft.date=2003-07-01&rft.volume=144&rft.issue=7&rft.spage=2807&rft.isbn=&rft.btitle=&rft.title=Endocrinology&rft.issn=00137227&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-07-22 N1 - Date created - 2003-06-17 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: Endocrinology. 2004 Jan;145(1):193 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The use of respiratory enzymes as biomarkers of petroleum hydrocarbon exposure in Mytilus edulis planulatus. AN - 73379113; 12798759 AB - The effect of exposure to petroleum hydrocarbons via the water column and through contaminated sediment upon changes in respiratory enzymes in the common mussel (Mytilus edulis planulatus) was investigated. Mussels were exposed to three concentrations of the water-accommodated fraction (WAF) of Bass Strait crude oil, for 24, 48, and 96 h. In a second study mussels were exposed to three concentrations of crude oil-contaminated sediment for 2 weeks and 1, 2, 4 and 6 months. Activities of citrate synthase (CS) and lactate dehydrogenase (LDH) were measured in the gills. In mussels exposed to WAF, a significant decrease in CS activity was observed over time (P0.05); neither treatment nor time had an effect on LDH activity. Exposure to contaminated sediment did not have a significant effect on CS activity, however, time had a significant effect on CS activity (P<0.05). Both time and treatment had an effect on LDH activity (P<0.05). Results demonstrated that changes in gill CS and LDH are not sensitive biomarkers of petroleum hydrocarbon exposure in M. edulis planulatus. JF - Ecotoxicology and environmental safety AU - Long, Sara M AU - Ryder, Kelly J AU - Holdway, Douglas A AD - Department of Biotechnology and Environmental Biology, RMIT-University, Bundoora Campus, GPO Box 71, Victoria 3083, Australia. slon@ceh.ac.uk Y1 - 2003/07// PY - 2003 DA - July 2003 SP - 261 EP - 270 VL - 55 IS - 3 SN - 0147-6513, 0147-6513 KW - Biomarkers KW - 0 KW - Hydrocarbons KW - Petroleum KW - Water Pollutants, Chemical KW - L-Lactate Dehydrogenase KW - EC 1.1.1.27 KW - Citrate (si)-Synthase KW - EC 2.3.3.1 KW - Index Medicus KW - Hydrocarbons -- analysis KW - Geologic Sediments -- chemistry KW - Animals KW - Time Factors KW - Hydrocarbons -- adverse effects KW - Bivalvia -- enzymology KW - Water Pollutants, Chemical -- analysis KW - Water Pollutants, Chemical -- adverse effects KW - L-Lactate Dehydrogenase -- pharmacology KW - L-Lactate Dehydrogenase -- analysis KW - Citrate (si)-Synthase -- analysis KW - Biomarkers -- analysis KW - Petroleum -- analysis KW - Environmental Exposure KW - Citrate (si)-Synthase -- pharmacology KW - Petroleum -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73379113?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecotoxicology+and+environmental+safety&rft.atitle=The+use+of+respiratory+enzymes+as+biomarkers+of+petroleum+hydrocarbon+exposure+in+Mytilus+edulis+planulatus.&rft.au=Long%2C+Sara+M%3BRyder%2C+Kelly+J%3BHoldway%2C+Douglas+A&rft.aulast=Long&rft.aufirst=Sara&rft.date=2003-07-01&rft.volume=55&rft.issue=3&rft.spage=261&rft.isbn=&rft.btitle=&rft.title=Ecotoxicology+and+environmental+safety&rft.issn=01476513&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-09-16 N1 - Date created - 2003-06-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Preserving Constitutional War Powers AN - 60674255; 200404615 AB - The US Congress's bipartisan passage of a resolution in Oct 2002 that granted President George W. Bush the authority to commence military strikes against Iraq is strongly criticized. An overview of the Bush administration's rationale for seeking such military authority is presented, emphasizing the administration's desire to protect national security interests & modernize the notion of presidential implied powers. It is asserted that the Bush administration's claims for greater military decision making are not supported by the US Constitution; nevertheless, it is acknowledged that the US president, not Congress, now possesses the power to determine how & when military force will be applied against other nations. The author's initial support for the Tonkin Gulf Resolution & subsequent repudiation of the decision that resulted in the US's increased involvement in Southeast Asia are cited to illustrate why Congress, not the executive, must retain war-making authority. It is concluded that future legislators must preserve Congress' authority to declare war in order to check executive power. J. W. Parker JF - Mediterranean Quarterly AU - Byrd, Robert C AD - US Congress Y1 - 2003/07// PY - 2003 DA - July 2003 SP - 1 EP - 5 VL - 14 IS - 3 SN - 1047-4552, 1047-4552 KW - Bush, George W. KW - Separation of Powers KW - Presidents KW - War KW - United States of America KW - Decision Making KW - Legislative Bodies KW - Political Power KW - Emergency Powers KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60674255?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mediterranean+Quarterly&rft.atitle=Preserving+Constitutional+War+Powers&rft.au=Byrd%2C+Robert+C&rft.aulast=Byrd&rft.aufirst=Robert&rft.date=2003-07-01&rft.volume=14&rft.issue=3&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Mediterranean+Quarterly&rft.issn=10474552&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Presidents; Legislative Bodies; Emergency Powers; Political Power; Decision Making; Separation of Powers; War; United States of America ER - TY - JOUR T1 - Class Action "Fairness" -- A Bad Deal for the States and Consumers AN - 60662445; 200405678 AB - The House of Representatives had repeatedly considered bills that would expand federal diversity jurisdiction to include class actions in which only minimal diversity exists between plaintiffs & defendants. Though three such bills have failed, members of Congress will probably propose another. Here, Representative Conyers (D-Mich.) argues that enacting this legislation would be a mistake. Such a change would add to the already heavy burdens of the federal court system & would obstruct state courts' application of both the substantive & the procedural law of their states. Expanding diversity jurisdiction in this manner would impose unfair disadvantages on class action plaintiffs, threatening suits against the tobacco & firearms industries, among others. Adapted from the source document. JF - Harvard Journal on Legislation AU - Conyers, John, Jr AD - United States House of Representatives Y1 - 2003/07// PY - 2003 DA - July 2003 SP - 493 EP - 511 VL - 40 IS - 2 SN - 0017-808X, 0017-808X KW - Courts KW - Jurisdiction KW - Defendants KW - Legislative Bodies KW - Legal Cases KW - Legislation KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60662445?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harvard+Journal+on+Legislation&rft.atitle=Class+Action+%22Fairness%22+--+A+Bad+Deal+for+the+States+and+Consumers&rft.au=Conyers%2C+John%2C+Jr&rft.aulast=Conyers&rft.aufirst=John&rft.date=2003-07-01&rft.volume=40&rft.issue=2&rft.spage=493&rft.isbn=&rft.btitle=&rft.title=Harvard+Journal+on+Legislation&rft.issn=0017808X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Legislation; Legislative Bodies; Jurisdiction; Courts; Defendants; Legal Cases ER - TY - JOUR T1 - Access to Classified Information: Seeking Security Clearances for State and Local Officials and Personnel AN - 60652609; 200321960 AB - The heightened priority to combat terrorism has revealed problems in intergovernmental cooperation, coordination, & communication. Part of the solution, as provided in the Homeland Security Information Sharing Act of 2002, is to grant security clearances to state & local officials & personnel involved in homeland security, to facilitate their access to federal government information, including classified national security (or other sensitive) information. Such a change would result in two developments unprecedented in their scope: requiring a security clearance for nonfederal officials across-the-board & for elected officials at any level, as standard policy. This study examines current, ad hoc, specialized arrangements in this area, which have led to inconsistencies & limitations among (potential) recipients; the rationale & recommendations to alter this approach; & the challenges & concerns, which have not been fully addressed. Adapted from the source document. JF - Government Information Quarterly AU - Kaiser, Frederick M AD - Library Congress, Washington, DC FKAISER@crs.loc.gov Y1 - 2003/07// PY - 2003 DA - July 2003 SP - 213 EP - 232 VL - 20 IS - 3 SN - 0740-624X, 0740-624X KW - Public Officials KW - Terrorism KW - Government Agencies KW - Information Dissemination KW - Intergovernmental Relations KW - Security Policy KW - National Security KW - article KW - 9263: public policy/administration; public administration/bureaucracy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60652609?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Government+Information+Quarterly&rft.atitle=Access+to+Classified+Information%3A+Seeking+Security+Clearances+for+State+and+Local+Officials+and+Personnel&rft.au=Kaiser%2C+Frederick+M&rft.aulast=Kaiser&rft.aufirst=Frederick&rft.date=2003-07-01&rft.volume=20&rft.issue=3&rft.spage=213&rft.isbn=&rft.btitle=&rft.title=Government+Information+Quarterly&rft.issn=0740624X&rft_id=info:doi/10.1016%2FS0740-624X%2803%2900040-6 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - GIQUEU N1 - SubjectsTermNotLitGenreText - Terrorism; Government Agencies; Intergovernmental Relations; National Security; Public Officials; Security Policy; Information Dissemination DO - http://dx.doi.org/10.1016/S0740-624X(03)00040-6 ER - TY - JOUR T1 - Sovereignty or Standard of Living? AN - 60585645; 200408308 AB - Analyzes the "big idea" of "deep integration" from a Canadian perspective, contending that of paramount importance to proponents is secure access to the US market. It is argued that deep integration is not merely an economic agenda; rather, it is about falling in line with the US from a position of weakness; ie, Canada has no choice. Further, the "big idea" is not purely economic & the real issue is the kind of relationship that Canada will have with the US, thus, the issue cannot be neatly divided in terms of economics & politics. Proponents of deep integration are linking trade & investment issues to other issues that go to the heart of political independence; they want Canada to support US demands for further access to Canadian energy; & they support a customs union, deemed deeply dangerous in terms of a common trade policy. Another critical point is that economic issues cannot be tidily separated from the sociocultural issues that define Canada as a nation. What it means to build a society centered on distinctive values & goals is discussed, noting another key issue as the extent to which economic integration with the US has undermined Canada's ability to distinguish itself from the US. The downside to integration with the FTA & NAFTA models is elaborated, & options for the future of integration are touched on. J. Zendejas JF - International Journal AU - Yussuff, Hassan AD - Canadian Labour Congress Y1 - 2003/07// PY - 2003 DA - July 2003 SP - 447 EP - 454 VL - 58 IS - 3 SN - 0020-7020, 0020-7020 KW - economic integration KW - Canada KW - United States of America KW - International Relations KW - National Identity KW - Political Integration KW - International Trade KW - article KW - 9063: international relations; international relations KW - 9103: politics; political culture UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60585645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal&rft.atitle=Sovereignty+or+Standard+of+Living%3F&rft.au=Yussuff%2C+Hassan&rft.aulast=Yussuff&rft.aufirst=Hassan&rft.date=2003-07-01&rft.volume=58&rft.issue=3&rft.spage=447&rft.isbn=&rft.btitle=&rft.title=International+Journal&rft.issn=00207020&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Canada; United States of America; Political Integration; International Relations; National Identity; International Trade ER - TY - JOUR T1 - Deciding on War against Iraq AN - 60144820; 200321143 AB - Explores the political context, intentions, & reasoning of Congressional legislators regarding the Iraq Resolution of 2002 that authorized the president to use military force against Iraq. The multiple messages & justifications for war made by the George W. Bush administration are analyzed. Rather than wait for resolution from the UN Security Council, Congress acted to empower the president. The upcoming political elections & 2004 presidential ambitions are identified as reasons for the resolution's endorsement by incumbent Democrats. Comparisons to the Tonkin Gulf Resolution of 1964 illustrate the lawmakers' deference to the president rather than assume the legislative duties of declaring war. The failure of Congress to question unsubstantiated executive claims on the dangers of Iraq is criticized. 48 References. L. Collins JF - Perspectives on Political Science AU - Fisher, Louis AD - Congressional Research Service, Library of Congress Y1 - 2003/07// PY - 2003 DA - July 2003 SP - 135 EP - 140 VL - 32 IS - 3 SN - 1045-7097, 1045-7097 KW - War KW - Legislators KW - United States of America KW - Iraq KW - article KW - 9105: politics; national-level politics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60144820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Perspectives+on+Political+Science&rft.atitle=Deciding+on+War+against+Iraq&rft.au=Fisher%2C+Louis&rft.aulast=Fisher&rft.aufirst=Louis&rft.date=2003-07-01&rft.volume=32&rft.issue=3&rft.spage=135&rft.isbn=&rft.btitle=&rft.title=Perspectives+on+Political+Science&rft.issn=10457097&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-10-30 N1 - Number of references - 48 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States of America; Iraq; War; Legislators ER - TY - JOUR T1 - Abundance estimators and truth: Accounting for individual heterogeneity in wild house mice AN - 19239181; 5810198 AB - We compared the actual abundance of 12 confined populations of wild house mice (Mus musculus) with closed population estimates based on mark-recapture data. Goodness-of-fit tests consistently detected individual heterogeneity in capture probability. Estimators designed to take such heterogeneity into account were expected to perform best, and generally did. However, of the 9 abundance estimators we considered, only Chao's modified moment estimator had no obvious bias and produced confidence intervals that always included the actual population size. The reliability of the 9 estimators and minimum number known alive (MNA), as indices of abundance, was quantified by (1) linear regression, and (2) calculating a Spearman rank correlation coefficient between the ranking obtained using the index and the true ranking. We found Petersen estimates to provide the most accurate ranking, and MNA also performed well. Since Chao's modified moment estimator was designed for populations with high levels of heterogeneity and low average capture probability we concluded that this is an accurate description of trap response for confined mice populations. Body-length frequency distributions and sex ratios for mice caught once, more than once, and not at all revealed that body length and sex could explain some of the observed individual heterogeneity. Males were more likely to enter traps than females, and large mice were more likely to be trapped than small mice. Field populations of house mice are monitored regularly throughout southeastern Australia because high densities cause considerable damage to wheat crops and place substantial stress on farming communities. We found that field populations trapped during the breeding season exhibit heterogeneity in capture probability similar to that for confined populations, with the same relationships between capture probability, sex, and body length. However, these relationships did not hold for the same field population later in the season when breeding and recruitment had ceased. Chao's modified moment estimator was applied to field data and found to be stable when populations were trapped for greater than or equal to 5 nights, but unreliable trapped for < 5 nights. JF - Journal of Wildlife Management AU - Davis, SA AU - Akison, L K AU - Farroway, L N AU - Singleton, G R AU - Leslie, KE AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra ACT 2601, Australia Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 634 EP - 645 PB - Wildlife Society VL - 67 IS - 3 SN - 0022-541X, 0022-541X KW - Ecology Abstracts KW - Wildlife management KW - Sex ratio KW - Abundance KW - Mus musculus KW - Trapping KW - Body length KW - D 04001:Methodology - general UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19239181?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Management&rft.atitle=Abundance+estimators+and+truth%3A+Accounting+for+individual+heterogeneity+in+wild+house+mice&rft.au=Davis%2C+SA%3BAkison%2C+L+K%3BFarroway%2C+L+N%3BSingleton%2C+G+R%3BLeslie%2C+KE&rft.aulast=Davis&rft.aufirst=SA&rft.date=2003-07-01&rft.volume=67&rft.issue=3&rft.spage=634&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Management&rft.issn=0022541X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Mus musculus; Abundance; Trapping; Wildlife management; Body length; Sex ratio ER - TY - JOUR T1 - Centrifugation facilitates transduction of green fluorescent protein in human monocytes and macrophages by adenovirus at low multiplicity of infection AN - 18834852; 5726450 AB - Due to their phagocytic and poorly proliferative nature, it has been difficult to transfect human monocytes and macrophages. Adenoviral vectors have recently allowed transduction of a high percentage of human macrophages, but only after CSF upregulation of the integrins, alpha v beta 3 or alpha v beta 5, during culture for 48 h, a time allowing significant monocyte to macrophage differentiation. In our hands, after 24-h incubation with M-CSF (20 ng/ml) and a further 24-h incubation with an adenoviral vector encoding green fluorescent protein (AdV-GFP) [multiplicity of infection (MOI)=50:1], only 35% of CD14-positive cells express GFP. We report that centrifugation of these cells with AdV-GFP at 2000g for 1 h at 37 degree C significantly enhanced the number of cells expressing GFP (to 65%) and the level of GFP expression per transduced cell (fivefold). The viability of the cells was not compromised (5 % CD14-positive cells were 7-aminoactinomycin D (7AAD)-positive after 24 h AdV-GFP exposure at MOI=50:1). Centrifugation allowed efficient transduction of monocytes and macrophages with an MOI at least tenfold lower than otherwise required and did not activate the transduced cells or affect their ability to produce TNF alpha or IL-1 beta in response to lipopolysaccharide (LPS). This methodology was also suitable for transducing large numbers of in vitro monocyte-derived macrophages (MDMac) and macrophages isolated from synovial fluids with up to 75-80% of CD14-positive cells transduced after 24-h exposure to AdV-GFP (50:1) and centrifugation (2000g). This methodology should provide significant expression of transgenes in human monocytes and macrophages. JF - Journal of Immunological Methods AU - Mayne, G C AU - Borowicz, R A AU - Greeneklee, K V AU - Finlay-Jones, J J AU - Williams, KA AU - Hart, PH AD - Department of Microbiology and Infectious Diseases, School of Medicine, Flinders University, GPO Box 2100, Adelaide 5001, Australia, Prue.Hart@flinders.edu.au Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 45 EP - 56 PB - Elsevier B.V. VL - 278 IS - 1-2 SN - 0022-1759, 0022-1759 KW - 7-aminoactinomycin D KW - green fluorescent protein KW - lipopolysaccharides KW - man KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts; Medical and Pharmaceutical Biotechnology Abstracts; Bioengineering Abstracts KW - F 06725:Leukocyte isolation, characterization & preservation KW - W3 33240:Immunology KW - W 30965:Miscellaneous, Reviews KW - W4 120:Genetic Engineering in Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18834852?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immunological+Methods&rft.atitle=Centrifugation+facilitates+transduction+of+green+fluorescent+protein+in+human+monocytes+and+macrophages+by+adenovirus+at+low+multiplicity+of+infection&rft.au=Mayne%2C+G+C%3BBorowicz%2C+R+A%3BGreeneklee%2C+K+V%3BFinlay-Jones%2C+J+J%3BWilliams%2C+KA%3BHart%2C+PH&rft.aulast=Mayne&rft.aufirst=G&rft.date=2003-07-01&rft.volume=278&rft.issue=1-2&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immunological+Methods&rft.issn=00221759&rft_id=info:doi/10.1016%2FS0022-1759%2803%2900229-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0022-1759(03)00229-1 ER - TY - JOUR T1 - Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry AN - 18815429; 5689296 AB - Phosphoinositides (phosphorylated derivatives of phosphatidylinositol, PI) are versatile intracellular signaling lipids whose occurrence in low concentrations complicates direct mass measurements. Here we present a sensitive method to detect, identify and quantify phosphatidylinositol phosphate (PIP) and phosphatidylinositol bisphosphate (PIP sub(2)) with different fatty acid compositions (phosphoinositide profiles) in total lipid extracts by electrospray ionization mass spectrometry (ESI-MS). Using this method, we detected elevated concentrations of PIP sub(2) in human fibroblasts from patients with Lowe syndrome, a genetic disorder that affects phosphoinositide metabolism. Saccharomyces cerevisiae cells deficient in enzymes involved in PIP metabolism - Sac1p, a phosphoinositide phosphatase, and Vps34p and Pik1p, a PI 3-kinase and PI 4-kinase, respectively - showed not only different PIP concentrations but also differential changes in PIP profiles indicating metabolic and/or subcellular pooling. Mass spectrometric analysis of phosphoinositides offers unique advantages over existing approaches and may represent a powerful diagnostic tool for human diseases that involve defective phosphoinositide metabolism. JF - Nature Biotechnology AU - Wenk, M R AU - Lucast, L AU - Di Paolo, G AU - Romanelli, A J AU - Suchy, S F AU - Nussbaum, R L AU - Cline, G W AU - Shulman, GI AU - McMurray, W AU - De Camilli, P AD - Howard Hughes Medical Institute, Department of Cell Biology, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06511, USA, markus.wenk@yale.edu Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 813 EP - 817 VL - 21 IS - 7 SN - 1087-0156, 1087-0156 KW - Lowe syndrome KW - phosphatidylinositol biphosphate KW - phosphatidylinositol phosphate KW - Biotechnology and Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - W3 33110:Instruments (devices) KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18815429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nature+Biotechnology&rft.atitle=Phosphoinositide+profiling+in+complex+lipid+mixtures+using+electrospray+ionization+mass+spectrometry&rft.au=Wenk%2C+M+R%3BLucast%2C+L%3BDi+Paolo%2C+G%3BRomanelli%2C+A+J%3BSuchy%2C+S+F%3BNussbaum%2C+R+L%3BCline%2C+G+W%3BShulman%2C+GI%3BMcMurray%2C+W%3BDe+Camilli%2C+P&rft.aulast=Wenk&rft.aufirst=M&rft.date=2003-07-01&rft.volume=21&rft.issue=7&rft.spage=813&rft.isbn=&rft.btitle=&rft.title=Nature+Biotechnology&rft.issn=10870156&rft_id=info:doi/10.1038%2Fnbt837 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1038/nbt837 ER - TY - JOUR T1 - Indicators of benzene emissions and exposure in Bangkok street AN - 18796794; 5656690 AB - Ambient benzene measurements were conducted for the first time at four air monitoring sites in the Bangkok metropolitan region (BMR), from January to December 2001. Analytical results show that the mean benzene concentrations range from 42.4 mu g/m super(3) at the Din Daeng urban site to 15.1 mu g/m super(3) at the Chaeng Wattana suburban site. The monitoring results show that at a larger distance from the roadside or a higher level from the street surface, the level of benzene decreases. Analysis of the ambient benzene concentrations was carried out with reference to meteorological influences and traffic density. In traffic analysis, the combined effects of street topography and traffic flows established high impact on the overall benzene concentration in Bangkok. Statistical analysis shows good correlations of blood benzene levels and trans, trans-muconic acid with ambient benzene and demonstrated substantial exposure from traffic. JF - Environmental Research AU - Leong, ST AU - Laortanakul, P AD - School of Environment, Resource and Development, Urban Environmental Engineering and Management Program, Asian Institute of Technology, G.P.O. Box 4, Klong Luang, Pathumthani 12120, Thailand, tet@ait.ac.th Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 173 EP - 181 PB - Elsevier Science (USA) VL - 92 IS - 3 SN - 0013-9351, 0013-9351 KW - emissions KW - Toxicology Abstracts KW - X 24156:Environmental impact UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18796794?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Research&rft.atitle=Indicators+of+benzene+emissions+and+exposure+in+Bangkok+street&rft.au=Leong%2C+ST%3BLaortanakul%2C+P&rft.aulast=Leong&rft.aufirst=ST&rft.date=2003-07-01&rft.volume=92&rft.issue=3&rft.spage=173&rft.isbn=&rft.btitle=&rft.title=Environmental+Research&rft.issn=00139351&rft_id=info:doi/10.1016%2FS0013-9351%2802%2900084-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0013-9351(02)00084-1 ER - TY - JOUR T1 - BIODIVERSITY RESEARCH: Performance of nonparametric species richness estimators in a high diversity plant community AN - 18790659; 5663026 AB - The efficiency of four nonparametric species richness estimators - first-order Jackknife, second-order Jackknife, Chao2 and Bootstrap - was tested using simulated quadrat sampling of two field data sets (a sandy 'Dune' and adjacent 'Swale') in high diversity shrublands (kwongan) in south-western Australia. The data sets each comprised > 100 perennial plant species and > 10 000 individuals, and the explicit (x-y co-ordinate) location of every individual. We applied two simulated sampling strategies to these data sets based on sampling quadrats of unit sizes 1/400th and 1 /100th of total plot area. For each site and sampling strategy we obtained 250 independent sample curves, of 250 quadrats each, and compared the estimators' performances by using three indices of bias and precision: MRE (mean relative error), MSRE (mean squared relative error) and OVER (percentage overestimation). The analysis presented here is unique in providing sample estimates derived from a complete, field-based population census for a high diversity plant community. In general the true reference value was approached faster for a comparable area sampled for the smaller quadrat size and for the swale field data set, which was characterized by smaller plant size and higher plant density. Nevertheless, at least 15-30% of the total area needed to be sampled before reasonable estimates of S sub(t) (total species richness) were obtained. In most field surveys, typically less than 1% of the total study domain is likely to be sampled, and at this sampling intensity underestimation is a problem. Results showed that the second-order Jackknife approached the actual value of S sub(t) more quickly than the other estimators. All four estimators were better than S sub(obs) (observed number of species). However, the behaviour of the tested estimators was not as good as expected, and even with large sample size (number of quadrats sampled) all of them failed to provide reliable estimates. First- and second-order Jackknives were positively biased whereas Chao2 and Bootstrap were negatively biased. The observed limitations in the estimators' performance suggests that there is still scope for new tools to be developed by statisticians to assist in the estimation of species richness from sample data, especially in communities with high species richness. JF - Diversity and Distributions AU - Chiarucci, A AU - Enright, N J AU - Perry, G L AU - Miller, B P AU - Lamont, B B AD - Dipartimento di Scienze Ambientali 'G. Sarfatti', Universita di Siena, Via P.A. Mattioli 4, 53100 Siena, Italy, School of Anthropology, Geography & Environmental Studies, University of Melbourne, Australia 3010, Department of Geography, King's College London, Strand, London WC2R 2LS U.K. and School of Environmental Biology, Curtin University of Technology, GPO Box UL1987 Perth, Australia 6001 Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 283 EP - 295 PB - Blackwell Science Ltd VL - 9 IS - 4 SN - 1366-9516, 1366-9516 KW - Ecology Abstracts KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18790659?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diversity+and+Distributions&rft.atitle=BIODIVERSITY+RESEARCH%3A+Performance+of+nonparametric+species+richness+estimators+in+a+high+diversity+plant+community&rft.au=Chiarucci%2C+A%3BEnright%2C+N+J%3BPerry%2C+G+L%3BMiller%2C+B+P%3BLamont%2C+B+B&rft.aulast=Chiarucci&rft.aufirst=A&rft.date=2003-07-01&rft.volume=9&rft.issue=4&rft.spage=283&rft.isbn=&rft.btitle=&rft.title=Diversity+and+Distributions&rft.issn=13669516&rft_id=info:doi/10.1046%2Fj.1472-4642.2003.00027.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1046/j.1472-4642.2003.00027.x ER - TY - JOUR T1 - An Inclusive Fitness-Based Exploration of the Origin of Soldiers: The Roles of Sex Ratio, Inbreeding, and Soldier Reproduction AN - 17941130; 5874410 AB - I present an inclusive fitness model for the origin of soldiers that incorporates soldier production of males and females, in haplodiploids and diploids. In this paper, the term soldier refers to an individual that is morphologically and/or behaviorally specialized for defense. However, the model presented here can usefully be extended to other helping behaviors that are episodic in nature and that impact the colony as a whole rather than helping behavior that is directed to specific individuals. In general, the results of the model show that proto-soldier reproduction via sib-mating increases the ease with which soldiering evolves. Male haplodiploids appear the most apt to evolve soldier behavior compared to female haplodiploids and diploids. Haplodiploid females are expected to produce a greater proportion of male dispersers relative to their production of female dispersers and thereby increase the predilection in females to evolve soldiering compared to diploid populations. Application of the model to gall-forming thrips in Australia reveals that species basal to the phylogenetic branch where soldiers are inferred to have evolved show a lower threshold for soldier evolution than more derived species. This phylogenetic pattern is consistent with soldier production of male and female offspring facilitating the origin of soldiering in the social gall-forming thrips. JF - Journal of Insect Behavior AU - Chapman, T W AD - School of Biological Sciences, Flinders University of South Australia, GPO Box 2100, Adelaide, SA 5001, Australia, tom.chapman@flinders.edu.au Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 481 EP - 501 PB - Kluwer Academic Publishers VL - 16 IS - 4 SN - 0892-7553, 0892-7553 KW - Insects KW - Ecology Abstracts; Entomology Abstracts; Animal Behavior Abstracts KW - Fitness KW - Sex ratio KW - Models KW - Soldiers KW - Reproduction KW - Inbreeding KW - Insecta KW - D 04003:Modeling, mathematics, computer applications KW - Y 25523:Insects KW - Z 05192:Reproductive behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17941130?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Insect+Behavior&rft.atitle=An+Inclusive+Fitness-Based+Exploration+of+the+Origin+of+Soldiers%3A+The+Roles+of+Sex+Ratio%2C+Inbreeding%2C+and+Soldier+Reproduction&rft.au=Chapman%2C+T+W&rft.aulast=Chapman&rft.aufirst=T&rft.date=2003-07-01&rft.volume=16&rft.issue=4&rft.spage=481&rft.isbn=&rft.btitle=&rft.title=Journal+of+Insect+Behavior&rft.issn=08927553&rft_id=info:doi/10.1023%2FA%3A1027351206403 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Insecta; Fitness; Sex ratio; Inbreeding; Reproduction; Soldiers; Models DO - http://dx.doi.org/10.1023/A:1027351206403 ER - TY - JOUR T1 - Seasonal variation and environmental influences on juvenile banana prawn (Penaeus merguiensis) abundance in a subtropical estuary (Logan River) of eastern Australia AN - 17576329; 5725653 AB - Although the life history-environment relationship for juvenile Penaeus merguiensis in tropical regions has been well documented, little is known about the species towards the subtropical limits of its range. Seasonal patterns of abundances of juvenile and postlarval P. merguiensis were studied in the Logan River, a subtropical estuary in eastern Australia from January 1998 to July 2000. Prawns were sampled using a small beam trawl at fortnightly intervals when they were abundant and monthly intervals at other times. The prawns ranged in size from 1.8 to 22mm in carapace length (CL), with a mean size ( plus or minus 1 SE) of 6.7 plus or minus 0.1mm CL and were caught at densities of up to 14.2 plus or minus 3.3 prawnsm super(-2). Postlarvae were caught from January to July, with peaks in April and May; and juveniles were abundant from December to June, although this varied between years. The numbers of postlarvae, temperature and rainfall explained 23% of the overall variation in juvenile catches. Temperature and rainfall also explained some of the variation in postlarval catches (9.9%). Recruitment varied considerably between years, and was the highest in years when rainfall was low (1998 and 2000). In general, both the seasonal patterns of catches of postlarval and juvenile P. merguiensis, and environmental processes affecting their abundance were similar to tropical areas. However, one notable difference was that recruitment occurred over a more restricted time period in the Logan River than in tropical regions. JF - Estuarine, Coastal and Shelf Science AU - Meager, J J AU - Vance, D J AU - Loneragan, N R AU - Williamson, I AD - School of Natural Resource Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia, justin.meager@ifm.uib.no Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 569 EP - 576 PB - Elsevier Ltd VL - 57 IS - 4 SN - 0272-7714, 0272-7714 KW - Banana prawn KW - Water Resources Abstracts; Oceanic Abstracts; Aqualine Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Seasonal Variations KW - Shrimp KW - Rainfall KW - Population density KW - Tropical Regions KW - Selenium KW - Environmental effects KW - ISEW, Australia, Queensland, Logan Estuary KW - Marine crustaceans KW - Rivers KW - Temperature effects KW - Juveniles KW - Density KW - Recruitment KW - Estuaries KW - Temperature KW - Brackish KW - Biomass KW - Fenneropenaeus merguiensis KW - Australia, Queensland, Logan R. KW - Population structure KW - Population number KW - AQ 00001:Water Resources and Supplies KW - O 1070:Ecology/Community Studies KW - Q1 08422:Environmental effects KW - SW 0890:Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17576329?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Seasonal+variation+and+environmental+influences+on+juvenile+banana+prawn+%28Penaeus+merguiensis%29+abundance+in+a+subtropical+estuary+%28Logan+River%29+of+eastern+Australia&rft.au=Meager%2C+J+J%3BVance%2C+D+J%3BLoneragan%2C+N+R%3BWilliamson%2C+I&rft.aulast=Meager&rft.aufirst=J&rft.date=2003-07-01&rft.volume=57&rft.issue=4&rft.spage=569&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2FS0272-7714%2802%2900375-X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-07-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Temperature effects; Selenium; Juveniles; Rainfall; Estuaries; Recruitment; Environmental effects; Population density; Population structure; Biomass; Marine crustaceans; Population number; Rivers; Seasonal Variations; Shrimp; Density; Temperature; Tropical Regions; Fenneropenaeus merguiensis; Australia, Queensland, Logan R.; ISEW, Australia, Queensland, Logan Estuary; Brackish DO - http://dx.doi.org/10.1016/S0272-7714(02)00375-X ER - TY - JOUR T1 - No Evidence of Dioxin Cancer Threshold AN - 14670099; 10647117 JF - Environmental Health Perspectives AU - Mackie, David AU - Liu, Junfeng AU - Loh, Yeong-Shang AU - Thomas, Valerie Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1145 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - DIOXINS KW - TETRACHLORODIBENZODIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14670099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=No+Evidence+of+Dioxin+Cancer+Threshold&rft.au=Mackie%2C+David%3BLiu%2C+Junfeng%3BLoh%2C+Yeong-Shang%3BThomas%2C+Valerie&rft.aulast=Mackie&rft.aufirst=David&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1145&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; DIOXINS; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Inhalation Exposure of Rats to Asphalt Fumes Generated at Paving Temperatures Alters Pulmonary Xenobiotic Metabolism Pathways Without Lung Injury AN - 14668208; 10647129 AB - Female SpragueDawley rats were exposed to asphalt fumes generated at paving temperatures, and pulmonary damage and inflammation were examined, along with the metabolic pathways of the lung involving both phase I and phase II enzymes. The rats were subjected to asphalt fume concentrations ranging 10.458.8 mg/m super(3) for periods ranging from a single 1-h exposure to exposure for 6 h/d for 5 d. Results showed that exposure did not cause acute damage to the alveolar airblood barrier, cytotoxicity, or inflammation, as indicated by acellular bronchoalveolar lavage fluid levels of protein and lactate dehydrogenase activity, polymorphonuclear infiltration, and chemiluminescence generation and cytokine production by alveolar macrophages. Inhalation of asphalt fumes also did not compromise the ability of alveolar macrophages to respond to zymosan or bacterial lipopolysaccharides ex vivo. However, a clear modulation of the pulmonary xenobiotic metabolic pathways was observed, with acute exposure producing a chemical effect that altered both phase I and phase II enzyme levels and activities in the lung. JF - Environmental Health Perspectives AU - Ma, Jane YC AU - Rengasamy, Apavoo AU - Frazer, Dave AU - Barger, Mark W AU - Hubbs, Ann F AU - Battelli, Lori AU - Tomblyn, Seith Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1215 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ASPHALT KW - AIR POLLUTION EFFECTS KW - ENZYME ACTIVITY KW - PULMONARY EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14668208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Inhalation+Exposure+of+Rats+to+Asphalt+Fumes+Generated+at+Paving+Temperatures+Alters+Pulmonary+Xenobiotic+Metabolism+Pathways+Without+Lung+Injury&rft.au=Ma%2C+Jane+YC%3BRengasamy%2C+Apavoo%3BFrazer%2C+Dave%3BBarger%2C+Mark+W%3BHubbs%2C+Ann+F%3BBattelli%2C+Lori%3BTomblyn%2C+Seith&rft.aulast=Ma&rft.aufirst=Jane&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1215&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; ASPHALT; ENZYME ACTIVITY; PULMONARY EFFECTS ER - TY - JOUR T1 - Particle Concentrations in Inner-City Homes of Children with Asthma: the Effect of Smoking, Cooking, and Outdoor Pollution AN - 14667482; 10647137 AB - In the homes of 328 asthmatic children living in low-income census tracts of seven US cities, concentrations of particles in indoor air were measured, along with other characteristics of the indoor home environments. Questionnaires were used to determine the likely sources of combustion-related particles in the home, including smoking, cooking, use of a wood stove or fireplace, use of candles or incense, and use of a gas or kerosene space-heater. The use of possible modifiers of particle concentrations, such as windows, air-conditioners, and fans, was ascertained, aS were possible sources of noncombustion particles. The mean indoor particle concentrations in smoking and nonsmoking homes were 46.5 and 17.8 mu g/m super(3), respectively, indicating that smoking, when present, was the dominant contributor. A smaller, but significant, contribution from cooking was noted. Other important contributors to indoor particles were found to be incense use, dusting, and infiltration of outdoor air. JF - Environmental Health Perspectives AU - Wallace, Lance A AU - Mitchell, Herman AU - O'Connor, George T AU - Neas, Lucas AU - Lippmann, Morton AU - Kattan, Meyer AU - Koenig, Jane Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1265 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - COMBUSTION KW - SOURCE MEASUREMENT KW - CIGARETTE SMOKE KW - PARTICULATES KW - SANITATION KW - AIR POLLUTION, INDOOR KW - INNER CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14667482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Particle+Concentrations+in+Inner-City+Homes+of+Children+with+Asthma%3A+the+Effect+of+Smoking%2C+Cooking%2C+and+Outdoor+Pollution&rft.au=Wallace%2C+Lance+A%3BMitchell%2C+Herman%3BO%27Connor%2C+George+T%3BNeas%2C+Lucas%3BLippmann%2C+Morton%3BKattan%2C+Meyer%3BKoenig%2C+Jane&rft.aulast=Wallace&rft.aufirst=Lance&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1265&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SANITATION; COMBUSTION; SOURCE MEASUREMENT; AIR POLLUTION, INDOOR; INNER CITY; CIGARETTE SMOKE; PARTICULATES ER - TY - JOUR T1 - Skin as a Route of Exposure and Sensitization in Chronic Beryllium Disease AN - 14667415; 10647127 AB - To assess whether skin exposure to beryllium particles provides an alternative route for sensitization to the metal, fluorescent dextran particle penetration of human skin was evaluated ex vivo with laser scanning confocal microscopy, and cutaneous sensitization of mice was studied using Be salts and Be oxide. Dextran beads that were 0.5 and 1 mu m in size penetrated into the epidermis of two of 11 skin samples flexed for 15 min, in five of 12 samples flexed for 30 min, and in nine of 16 samples flexed for 60 min. In mice, cutaneous application of Be induced a Be-specific murine delayed-type hypersensitivity. Results from flow cytometry and a Be-stimulated lymphocyte proliferation test showed that the murine response to topical Be occurred in the lymph node draining the site of application, and T cells were activated and released into the peripheral blood. JF - Environmental Health Perspectives AU - Tinkle, Sally S AU - Antonini, James M AU - Rich, Brenda A AU - Roberts, Jenny R AU - Salmen, Rebecca AU - DePree, Karyn AU - Adkins, Eric J Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1202 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SENSITIVITY KW - BERYLLIUM KW - DISEASES AND DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14667415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Skin+as+a+Route+of+Exposure+and+Sensitization+in+Chronic+Beryllium+Disease&rft.au=Tinkle%2C+Sally+S%3BAntonini%2C+James+M%3BRich%2C+Brenda+A%3BRoberts%2C+Jenny+R%3BSalmen%2C+Rebecca%3BDePree%2C+Karyn%3BAdkins%2C+Eric+J&rft.aulast=Tinkle&rft.aufirst=Sally&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1202&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t maps N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SENSITIVITY; DISEASES AND DISORDERS; BERYLLIUM ER - TY - JOUR T1 - Bisphenol A Is Released from Used Polycarbonate Animal Cages into Water at Room Temperature AN - 14667370; 10647124 AB - The ability of used polycarbonate animal cages, which are used commonly to house laboratory animals, to release bisphenol A to water under normal use conditions of room temperature and a neutral solvent was investigated. New polycarbonate cages and new polysulfone cages were also studied. The bioactivity of the cage water samples was tested in an in vitro cell proliferation assay using estrogen-sensitive MCF-7 human breast cancer cells. The in vivo estrogenic bioactivity of the used cages was evaluated by measuring the uterine wet weight of prepubertal female mice housed in the cages. Results indicated that higher levels of bisphenol A migrated from the used polycarbonate cages than from the new polycarbonate or new polysulfone cages. The amount of bisphenol A released from the cages decreased over successive leaching experiments. The leached bisphenol A stimulated a significant increase in MCF-7 cell proliferation compared with control media and glass dish negative controls, and the bioactivity was confirmed by the subsequent addition of an antiestrogen, which inhibited the estrogen-mediated proliferative effect. In addition, prepubertal uterine wet weight was approximately 16% greater in female mice housed in the used polycarbonate caging with used polycarbonate water bottles relative to animals housed in used polypropylene cages, but the difference was not statistically significant. JF - Environmental Health Perspectives AU - Howdeshell, Kembra L AU - Peterman, Paul H AU - Judy, Barbara M AU - Taylor, Julia A AU - Orazio, Carl E AU - Ruhlen, Rachel L AU - vom Saal, Frederick S Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1180 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - LABORATORY ANIMALS KW - PLASTICS KW - HORMONAL EFFECTS KW - BIOASSAY KW - LEACHING KW - WATER POLLUTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14667370?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Bisphenol+A+Is+Released+from+Used+Polycarbonate+Animal+Cages+into+Water+at+Room+Temperature&rft.au=Howdeshell%2C+Kembra+L%3BPeterman%2C+Paul+H%3BJudy%2C+Barbara+M%3BTaylor%2C+Julia+A%3BOrazio%2C+Carl+E%3BRuhlen%2C+Rachel+L%3Bvom+Saal%2C+Frederick+S&rft.aulast=Howdeshell&rft.aufirst=Kembra&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1180&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - LABORATORY ANIMALS; LEACHING; PLASTICS; HORMONAL EFFECTS; BIOASSAY; WATER POLLUTION ER - TY - JOUR T1 - Polybrominated Diphenyl Ethers in Maternal and Fetal Blood Samples AN - 14666238; 10647134 AB - Maternal and fetal blood samples were collected from subjects in central Indiana, and concentrations of polybrominated diphenyl ethers (PBDEs) were measured. Maternal blood was obtained when the patient was admitted to the labor and delivery suite, and fetal blood was obtained from the umbilical cord vein after delivery. None of the 12 mothers studied had any occupational exposure to PBDEs. Six different congeners were detected in the serum samples, with BDE-47 accounting for the majority of the total, followed by BDE-99. The PBDE concentrations in maternal and fetal blood samples ranged 15580 and 14460 ng/g lipid, respectively. No correlations were found between PBDE concentrations and age, body mass index, or thyroid hormone levels. JF - Environmental Health Perspectives AU - Mazdai, Anita AU - Dodder, Nathan G AU - Abernathy, Mary Pell AU - Hites, Ronald A AU - Bigsby, Robert M Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1249 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ETHERS KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - FLAME RETARDANTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666238?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Polybrominated+Diphenyl+Ethers+in+Maternal+and+Fetal+Blood+Samples&rft.au=Mazdai%2C+Anita%3BDodder%2C+Nathan+G%3BAbernathy%2C+Mary+Pell%3BHites%2C+Ronald+A%3BBigsby%2C+Robert+M&rft.aulast=Mazdai&rft.aufirst=Anita&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1249&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ETHERS; BLOOD ANALYSIS; REPRODUCTION, HUMAN; FLAME RETARDANTS ER - TY - JOUR T1 - Distribution of Methyl Sulfone Metabolites of Polychlorinated Biphenyls and p,p'-DDE in Human Tissues AN - 14666210; 10647130 AB - In Belgium, human tissues were collected in 2002 from 11 subjects during medicolegal autopsy who had died suddenly from causes unrelated to environmental contamination, and methyl sulfone metabolites of PCBs and p,p'-DDE were examined, along with PCBs and p,p'-DDE. The sum of PCBs and p,p'-DDE was similar in adipose tissue and liver from the same subject, but higher concentrations of methyl sulfone metabolites were found in liver compared to other tissues. Correlation coefficients between the sum of methyl sulfone metabolites and the sum of the parent compounds were not high. JF - Environmental Health Perspectives AU - Chu, Shaogang AU - Covaci, Adrian AU - Jacobs, Werner AU - Haraguchi, Koichi AU - Schepens, Paul Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1222 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - METABOLIC ACTIVATION KW - DDE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Distribution+of+Methyl+Sulfone+Metabolites+of+Polychlorinated+Biphenyls+and+p%2Cp%27-DDE+in+Human+Tissues&rft.au=Chu%2C+Shaogang%3BCovaci%2C+Adrian%3BJacobs%2C+Werner%3BHaraguchi%2C+Koichi%3BSchepens%2C+Paul&rft.aulast=Chu&rft.aufirst=Shaogang&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1222&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; METABOLIC ACTIVATION; DDE ER - TY - JOUR T1 - Effects of the Isoflavones Genistein and Equol on the Gonadal Development of Japanese Medaka (Oryzias latipes) AN - 14666168; 10647120 AB - Recent studies have shown that isoflavone compounds, including genistein and equol, are discharged in effluents from sewage-treatment plants and from pulp mills and are present in agricultural runoff from intensive livestock operations. In this study, the impacts of waterborne exposures to equol and genistein on the development and differentiation of the gonad and the expression of secondary sex characteristics in Japanese medaka Oryzias latipes were investigated. Reproductive development assays were conducted according to an existing protocol. The most well-defined developmental response observed in both isoflavone treatments was the induction of gonadal intersex, as characterized by the presence of testis-ova. Equol caused a concentration-dependent increase in the incidence, but genistein induced only a low incidence at the highest test concentration. In addition, spermatogenesis was inhibited in males exposed to both treatments, and there was a significant increase in the amount of fibrotic tissue around the testicular lobules in some fish. Both compounds also altered development of the ovary and oogenesis in female medaka. JF - Environmental Health Perspectives AU - Kiparissis, Yiannis AU - Balch, Gordon C AU - Metcalfe, Tracy L AU - Metcalfe, Chris D Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1158 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSE RESPONSE PROFILES KW - HORMONAL EFFECTS KW - REPRODUCTION, FISH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+the+Isoflavones+Genistein+and+Equol+on+the+Gonadal+Development+of+Japanese+Medaka+%28Oryzias+latipes%29&rft.au=Kiparissis%2C+Yiannis%3BBalch%2C+Gordon+C%3BMetcalfe%2C+Tracy+L%3BMetcalfe%2C+Chris+D&rft.aulast=Kiparissis&rft.aufirst=Yiannis&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1158&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; HORMONAL EFFECTS; REPRODUCTION, FISH ER - TY - JOUR T1 - The Work Environment and Workers' Health in Four Large Office Buildings AN - 14665972; 10647133 AB - Beginning in May 1997, 98 occupants of 21 offices with open stations in four office buildings in Boston, MA, were recruited to examine the associations between environmental factors and workers' health. Intensive environmental sampling was conducted every six weeks at the workstations for airborne culturable fungi, dust-borne culturable fungi, temperature, relative humidity, carbon dioxide concentrations, water activities of floor carpets, and surface dust levels on nontextile furniture. Comprehensive questionnaires were administered to the subjects at each sampling event to ascertain perceptions of their health and comfort. Total fungi concentrations recovered from chair dust were associated positively with upper respiratory symptoms and nonspecific symptoms. A significant quadratic relationship was found between total airborne fungal concentrations and upper respiratory symptoms. Carbon dioxide concentrations, which were below recommended standards, were associated with upper respiratory symptoms before adjustment for self-reported working conditions, and the amount of floor dust was a significant predictor of eye irritation. A history of asthma was associated positively with eye irritation and nonspecific symptoms and correlated marginally with upper respiratory symptoms. The number of people in the office was related positively with nonspecific and upper respiratory symptoms. JF - Environmental Health Perspectives AU - Chao, HJasmine AU - Schwartz, Joel AU - Milton, Donald K AU - Burge, Harriet A Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1242 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - OFFICE BUILDINGS KW - RESPIRATORY DISORDERS KW - EYE IRRITATION KW - RESPIRABLE DUST KW - FUNGI KW - CARBON DIOXIDE KW - DUST FALL KW - AIR POLLUTION, INDOOR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14665972?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Work+Environment+and+Workers%27+Health+in+Four+Large+Office+Buildings&rft.au=Chao%2C+HJasmine%3BSchwartz%2C+Joel%3BMilton%2C+Donald+K%3BBurge%2C+Harriet+A&rft.aulast=Chao&rft.aufirst=HJasmine&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1242&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FUNGI; CARBON DIOXIDE; DUST FALL; OFFICE BUILDINGS; RESPIRATORY DISORDERS; AIR POLLUTION, INDOOR; RESPIRABLE DUST; EYE IRRITATION ER - TY - JOUR T1 - Human Prenatal and Postnatal Exposure to Polybrominated Diphenyl Ethers, Polychlorinated Biphenyls, Polychlorobiphenylols, and Pentachlorophenol AN - 14665940; 10647132 AB - Samples of maternal blood plasma, cord blood plasma, and breast milk were collected during 200001 from 15 randomly selected mothers living in Stockholm, Sweden, and concentrations of polybrominated diphenyl ethers (PBDEs), PCBs, polychlorobiphenylols, and pentachlorophenol were measured and compared. The median sums of PBDEs were 2.07, 1.69, and 2.14 ng/g lipids in maternal blood plasma, cord blood plasma, and breast milk, respectively, while those of PCBs were 176, 104, and 190 ng/g, respectively. The median sums of 12 polychlorobiphenylols in maternal blood plasma, cord blood plasma, and breast milk were 124, 88, and 3 pg/g, respectively, and the concentrations of pentachlorophenol were 2.83, 1.96, and 0.02 ng/g, respectively. The data suggested that the fetus was exposed continuously to the compounds during development. JF - Environmental Health Perspectives AU - Guvenius, Daiva Meironyte AU - Aronsson, Anette AU - Ekman-Ordeberg, Gunvor AU - Bergman, Ake AU - Noren, Koidu Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1235 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ETHERS KW - POLYCHLORINATED BIPHENYLS KW - BREAST MILK KW - PENTACHLOROPHENOL KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - FLAME RETARDANTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14665940?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Human+Prenatal+and+Postnatal+Exposure+to+Polybrominated+Diphenyl+Ethers%2C+Polychlorinated+Biphenyls%2C+Polychlorobiphenylols%2C+and+Pentachlorophenol&rft.au=Guvenius%2C+Daiva+Meironyte%3BAronsson%2C+Anette%3BEkman-Ordeberg%2C+Gunvor%3BBergman%2C+Ake%3BNoren%2C+Koidu&rft.aulast=Guvenius&rft.aufirst=Daiva&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1235&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ETHERS; POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; REPRODUCTION, HUMAN; BREAST MILK; PENTACHLOROPHENOL; FLAME RETARDANTS ER - TY - JOUR T1 - High Body Burdens of 2,2',4,4'-Tetrabromodiphenyl Ether (BDE-47) in California Women AN - 14665919; 10647123 AB - Breast adipose and serum samples were collected from women living in the San Francisco Bay area, CA, during the course of two separate epidemiologic studies in the late 1990s, and concentrations of polybrominated diphenyl ether were measured. The concentrations were compared to those measured in archived serum samples collected in the early 1960s. Brominated diphenyl ether (BDE)-47 was the major congener in all adipose samples, at concentrations ranging 5.2196.0 ng/g lipid, but BDE-99, -100, and -153 were also detected. In the serum collected in the 1990s, BDE-47 concentrations ranged from <10 to 511 ng/g lipid, while none of the serum samples from the 1960s contained the congener. For US-born women, a significant negative correlation was found between BDE-47 concentration and age, but the correlation was not significant for the sample of Laotian women or for the two groups combined. JF - Environmental Health Perspectives AU - Petreas, Myrto AU - She, Jianwen AU - Brown, FReber AU - Winkler, Jennifer AU - Windham, Gayle AU - Rogers, Evan AU - Zhao, Guomao Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1175 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ETHERS KW - BIOACCUMULATION, HUMAN KW - CALIFORNIA KW - BLOOD ANALYSIS KW - FLAME RETARDANTS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14665919?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=High+Body+Burdens+of+2%2C2%27%2C4%2C4%27-Tetrabromodiphenyl+Ether+%28BDE-47%29+in+California+Women&rft.au=Petreas%2C+Myrto%3BShe%2C+Jianwen%3BBrown%2C+FReber%3BWinkler%2C+Jennifer%3BWindham%2C+Gayle%3BRogers%2C+Evan%3BZhao%2C+Guomao&rft.aulast=Petreas&rft.aufirst=Myrto&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1175&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ETHERS; CALIFORNIA; BLOOD ANALYSIS; BIOACCUMULATION, HUMAN; FLAME RETARDANTS; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Toxicologic and Epidemiologic Clues from the Characterization of the 1952 London Smog Fine Particulate Matter in Archival Autopsy Lung Tissues AN - 14665912; 10647128 AB - Over a 5-d period in December 1952, an intense smog event occurred in London, UK, which was characterized by stagnant air masses trapped by a temperature inversion, and older members of the population were affected disproportionately. The most important causes of death during the event were bronchitis, influenza, pneumonia, other respiratory diseases, and heart disease. Autopsy records for selected years in the 1950s and 1960s at the Royal London Hospital were reviewed to determine the availability of archived preserved lung tissues from persons dying at the time of the event, and the archived samples were analyzed for inhaled particulate matter (PM). Microanalysis of lung tissue revealed that the common feature of the exogenous PM in all lung compartments was an aggregation of very fine carbonaceous material associated with a variety of fine inorganic particles. Airway aggregate PM was identified in two of the cases, airspace macrophage-bound PM and lymph node-macrophage-bound PM. Certain heavy-metal-bearing particle types that were abundant in the most recent retention compartment of the lung tissue were almost totally absent from the longer-term storage compartments. JF - Environmental Health Perspectives AU - Hunt, Andrew AU - Abraham, Jerrold L AU - Judson, Bret AU - Berry, Colin L Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1209 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PATHOLOGY, HUMAN KW - SMOG, PHOTOCHEMICAL KW - URBAN ATMOSPHERE KW - PARTICULATES KW - PULMONARY EFFECTS KW - UNITED KINGDOM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14665912?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Toxicologic+and+Epidemiologic+Clues+from+the+Characterization+of+the+1952+London+Smog+Fine+Particulate+Matter+in+Archival+Autopsy+Lung+Tissues&rft.au=Hunt%2C+Andrew%3BAbraham%2C+Jerrold+L%3BJudson%2C+Bret%3BBerry%2C+Colin+L&rft.aulast=Hunt&rft.aufirst=Andrew&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1209&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PATHOLOGY, HUMAN; PULMONARY EFFECTS; SMOG, PHOTOCHEMICAL; PARTICULATES; URBAN ATMOSPHERE; UNITED KINGDOM ER - TY - JOUR T1 - The Temporal Pattern of Respiratory and Hearth Disease Mortality in Response to Air Pollution AN - 14664137; 10647125 AB - Data collected during the Air Pollution and Health: a European Approach project were used to examine mortality displacement by age, noting differences between cardiovascular and respiratory deaths compared with all causes of death. The original study examined mortality displacement between air pollution and all daily deaths. For the ten European cities of the study, a 4.2% increase in respiratory deaths was found for a 10 mu g/m super(3) increase in PM sub(10) concentration. For respiratory deaths, the estimated immediate effect of PM sub(10) decreased much more slowly than it did for cardiovascular disease. A 2.06% increase in cardiovascular disease morality was found for the 64- to 75-yr-olds for a 10 mu g/m super(3) increase in PM sub(10), increasing to 2.35% for greater than or equal to 75-yr-old group. For the oldest group, a 4.75% increase in respiratory disease was found for the increase in PM sub(10). JF - Environmental Health Perspectives AU - Zanobetti, Antonella AU - Schwartz, Joel AU - Samoli, Evi AU - Gryparis, Alexandros AU - Touloumi, Giota AU - Peacock, Janet AU - Anderson, Ross H Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1188 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CARDIOVASCULAR EFFECTS KW - RESPIRATORY DISORDERS KW - AGE COMPARISONS KW - URBAN ATMOSPHERE KW - PARTICULATES KW - HEART DISEASE KW - MORTALITY PATTERNS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14664137?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Temporal+Pattern+of+Respiratory+and+Hearth+Disease+Mortality+in+Response+to+Air+Pollution&rft.au=Zanobetti%2C+Antonella%3BSchwartz%2C+Joel%3BSamoli%2C+Evi%3BGryparis%2C+Alexandros%3BTouloumi%2C+Giota%3BPeacock%2C+Janet%3BAnderson%2C+Ross+H&rft.aulast=Zanobetti&rft.aufirst=Antonella&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1188&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; CARDIOVASCULAR EFFECTS; HEART DISEASE; RESPIRATORY DISORDERS; MORTALITY PATTERNS; AGE COMPARISONS; PARTICULATES; URBAN ATMOSPHERE ER - TY - JOUR T1 - The Relationship Between Environmental Exposures to Phthalates and DNA Damage in Human Sperm Using the Neutral Comet Assay AN - 14664121; 10647121 AB - The neutral comet assay was used to measure DNA integrity in human sperm and to examine whether DNA integrity was associated with urinary concentrations of five phthalate monoesters. The human subjects were recruited from an ongoing semen quality study. Monoethyl phthalate (MEP) was detected in all urine samples, and mono-2-ethylhexyl phthalate and monomethyl phthalate were detected in at least 75% of the subjects. A statistically significant positive association was found between urinary MEP content and mean comet extent, along with a suggestive association with tail distributed moment. No significant associations were found between comet assay parameters and other urinary phthalate metabolites. JF - Environmental Health Perspectives AU - Duty, Susan M AU - Singh, Narendra P AU - Silva, Manori J AU - Barr, Dana B AU - Brock, John W AU - Ryan, Louise AU - Herrick, Robert F Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1164 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SPERM KW - PHTHALIC ACID ESTERS KW - DNA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14664121?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+Between+Environmental+Exposures+to+Phthalates+and+DNA+Damage+in+Human+Sperm+Using+the+Neutral+Comet+Assay&rft.au=Duty%2C+Susan+M%3BSingh%2C+Narendra+P%3BSilva%2C+Manori+J%3BBarr%2C+Dana+B%3BBrock%2C+John+W%3BRyan%2C+Louise%3BHerrick%2C+Robert+F&rft.aulast=Duty&rft.aufirst=Susan&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1164&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SPERM; PHTHALIC ACID ESTERS; DNA ER - TY - JOUR T1 - A Climate-Based Model Predicts the Spatial Distribution of the Lyme Disease Vector Ixodes scapularis in the United States AN - 14664086; 10647119 JF - Environmental Health Perspectives AU - Brownstein, John S AU - Holford, Theodore R AU - Fish, Durland Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1152 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CARTOGRAPHY KW - MATHEMATIC MODELS, BIOLOGICAL KW - SPATIAL COMPARISONS KW - CLIMATOLOGY KW - RISK ASSESSMENT KW - DISEASES AND DISORDERS KW - ECOLOGY, INSECT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14664086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Climate-Based+Model+Predicts+the+Spatial+Distribution+of+the+Lyme+Disease+Vector+Ixodes+scapularis+in+the+United+States&rft.au=Brownstein%2C+John+S%3BHolford%2C+Theodore+R%3BFish%2C+Durland&rft.aulast=Brownstein&rft.aufirst=John&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1152&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; CLIMATOLOGY; CARTOGRAPHY; ECOLOGY, INSECT; DISEASES AND DISORDERS; SPATIAL COMPARISONS; MATHEMATIC MODELS, BIOLOGICAL ER - TY - JOUR T1 - Birth Malformations and Other Adverse Perinatal Outcomes in Four U.S. Wheat-Producing States AN - 14663894; 10647136 AB - Birth malformations among 199597 births in agricultural, rural counties of Minnesota, Montana, North Dakota, and South Dakota were investigated, comparing high- to low-wheat-producing counties. Information on newborns and infants was obtained from the National Center for Health Statistics, and agricultural information was obtained from the USDA 1992 census. Chlorophenoxy herbicides were applied predominantly to spring and durum wheat. In high-wheat counties, significant increases were observed for circulatory/respiratory and musculoskeletal/integumental anomalies among combined male and female births, and for infant death from congenital anomalies among boys. Boys conceived during AprilJune and born in high-wheat counties were almost five times more likely to be diagnosed with a birth anomaly than were boys in low-wheat counties conceived during other months of the year. JF - Environmental Health Perspectives AU - Schreinemachers, Dina M Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1259 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MONTANA KW - SPATIAL COMPARISONS KW - WHEAT KW - NORTH DAKOTA KW - SOUTH DAKOTA KW - BIRTH DEFECTS, HUMAN KW - HERBICIDE EXPOSURE KW - MINNESOTA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Birth+Malformations+and+Other+Adverse+Perinatal+Outcomes+in+Four+U.S.+Wheat-Producing+States&rft.au=Schreinemachers%2C+Dina+M&rft.aulast=Schreinemachers&rft.aufirst=Dina&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1259&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MONTANA; SOUTH DAKOTA; SPATIAL COMPARISONS; MINNESOTA; HERBICIDE EXPOSURE; BIRTH DEFECTS, HUMAN; NORTH DAKOTA; WHEAT ER - TY - JOUR T1 - Assessment of Pre- and Postnatal Exposure to Polychlorinated Biphenyls: Lessons from the Inuit Cohort Study AN - 14663662; 10647135 AB - The Inuit Cohort Study was initiated in 1995 to investigate adverse neurodevelopmental effects induced by developmental PCB exposure in Inuit infants from Nunavik, PQ, Canada. Concentrations of 14 PCB congeners and 11 chlorinated pesticides were measured in maternal plasma, umbilical cord plasma, and breast milk samples, and postnatal exposure was evaluated by quantifying PCBs in plasma samples from six-month-old infants. Results showed that, when expressed on a lipid basis, concentrations of PCB-153 in umbilical cord plasma, maternal plasma, and breast milk were highly intercorrelated. Infant PCB plasma concentration was predicted best by a model that contained measures of maternal PCB concentration in body lipids, breast-feeding duration, and infant fat mass. Infants who were breast-fed for more than three months displayed a mean plasma PCB concentration 6.6-fold higher than that of bottle-fed infants. Cord plasma PCB concentrations were, on average, 81% of those in maternal plasma, indicating that the placenta did not constitute a barrier to the transfer of major PCB congeners from the mother to the fetus. JF - Environmental Health Perspectives AU - Ayotte, Pierre AU - Muckle, Gina AU - Jacobson, Joseph L AU - Jacobson, Sandra W AU - Dewailly, Eric Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1253 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - BREAST MILK KW - QUEBEC PROVINCE KW - BREAST FEEDING KW - BLOOD ANALYSIS KW - INDIGENOUS PEOPLE KW - REPRODUCTION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663662?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Pre-+and+Postnatal+Exposure+to+Polychlorinated+Biphenyls%3A+Lessons+from+the+Inuit+Cohort+Study&rft.au=Ayotte%2C+Pierre%3BMuckle%2C+Gina%3BJacobson%2C+Joseph+L%3BJacobson%2C+Sandra+W%3BDewailly%2C+Eric&rft.aulast=Ayotte&rft.aufirst=Pierre&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1253&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; POLYCHLORINATED BIPHENYLS; INDIGENOUS PEOPLE; REPRODUCTION, HUMAN; BREAST MILK; QUEBEC PROVINCE; BREAST FEEDING ER - TY - JOUR T1 - A Study of Urban Housing Demolitions as Sources of Lead in Ambient Dust: Demolition Practices and Exterior Dust Fall AN - 14663629; 10647131 AB - At three urban housing demolition sites in low-income neighborhoods of Baltimore, MD, the effect of demolition on lead levels in ambient dust was investigated. Demolition at each site was performed using track-mounted excavator equipment with either a claw bucket or a material handler. Lead was determined in paint samples from the sites prior to demolition, and dust-fall samples were collected at baseline, during demolition, and during debris removal. Demolition and debris removal were found to be associated with significant and acute increases in Pb dust fall within 10 m of the demolition sites, and the increase was greater during demolition than during debris removal. Lead dust fall tended to be highest at sampling locations closest to the active work areas and at downwind locations. The Pb concentrations during demolition and debris removal ranged 12006900 and 5605100 mg/kg, respectively. The public health implications of the findings are discussed. JF - Environmental Health Perspectives AU - Farfel, Mark R AU - Orlova, Anna O AU - Lees, Peter SJ AU - Rohde, Charles AU - Ashley, Peter J AU - Chisolm, JJulian Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1228 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HOUSING KW - DUST FALL KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Study+of+Urban+Housing+Demolitions+as+Sources+of+Lead+in+Ambient+Dust%3A+Demolition+Practices+and+Exterior+Dust+Fall&rft.au=Farfel%2C+Mark+R%3BOrlova%2C+Anna+O%3BLees%2C+Peter+SJ%3BRohde%2C+Charles%3BAshley%2C+Peter+J%3BChisolm%2C+JJulian&rft.aulast=Farfel&rft.aufirst=Mark&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1228&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HOUSING; DUST FALL; LEAD ER - TY - JOUR T1 - Arsenic Groundwater Contamination in Middle Ganga Plain, Bihar, India: a Future Danger? AN - 14662503; 10647126 AB - In Semria Ojha Patti village of Ara in the Bhojpur District of Bihar, India, groundwater samples were collected and analyzed for levels of arsenic, and the prevalence of As toxicity was determined. Besides water, samples of human hair, nail, and urine were analyzed for As concentrations. Of the 206 tube-well samples examined, 56.8% contained As concentrations higher than 50 mu g/l, and 19.9% had concentrations higher than 300 mu g/l. The arsenical skin lesions observed in the village were similar to those noted in West Bengal, India, and in Bangladesh. The data showed that 57.6 and 76.3% of the hair and nail samples, respectively, had As concentrations above the normal range. Of 40 cases examined, 21 were clinically diagnosed with As neuropathy, all of which had arsenical skin lesions and elevated levels of As in their hair, nails, and urine. The data also suggested an increase in fetal loss and premature delivery in women with the highest concentrations of As in their drinking water. JF - Environmental Health Perspectives AU - Chakraborti, Dipankar AU - Mukherjee, Subhash C AU - Pati, Shyamapada AU - Sengupta, Mrinal K AU - Rahman, Mohammad M AU - Chowdhury, Uttam K AU - Lodh, Dilip Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1194 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - GROUNDWATER KW - BIOACCUMULATION, HUMAN KW - ARSENIC KW - DISEASES AND DISORDERS KW - REPRODUCTION, HUMAN KW - WATER, DRINKING KW - INDIA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14662503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Arsenic+Groundwater+Contamination+in+Middle+Ganga+Plain%2C+Bihar%2C+India%3A+a+Future+Danger%3F&rft.au=Chakraborti%2C+Dipankar%3BMukherjee%2C+Subhash+C%3BPati%2C+Shyamapada%3BSengupta%2C+Mrinal+K%3BRahman%2C+Mohammad+M%3BChowdhury%2C+Uttam+K%3BLodh%2C+Dilip&rft.aulast=Chakraborti&rft.aufirst=Dipankar&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1194&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; DISEASES AND DISORDERS; ARSENIC; REPRODUCTION, HUMAN; WATER, DRINKING; INDIA; BIOACCUMULATION, HUMAN; GROUNDWATER ER - TY - JOUR T1 - Assessing Human Exposure to Phthalates Using Monoesters and Their Oxidized Metabolites as Biomarkers AN - 14662478; 10647118 AB - Given the use of phthalates in a range of consumer products, the potential for nonoccupational exposure is high, and after exposure, phthalates are hydrolyzed rapidly to their respective monoesters, which can be biotransformed further to oxidative metabolites. Di-(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate, and their monoester metabolites appear to have the greatest potential toxicity. An assessment is provided of methods to determine exposure to phthalates using monoesters and their oxidized metabolites as biomarkers. The data examined support the widespread nature of human exposure, but the measurement of phthalate metabolites in humans does not, by itself, mean that phthalates cause disease. However, the data suggest that mono-(2-ethylhexyl) phthalate is a valid DEHP biomarker when looking at health endpoints. JF - Environmental Health Perspectives AU - Barr, Dana B AU - Silva, Manori J AU - Kato, Kayoko AU - Reidy, John A AU - Malek, Nicole A AU - Hurtz, Donald AU - Sadowski, Melissa Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1148 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - METABOLIC ACTIVATION KW - BIOLOGICAL INDICATORS KW - PHTHALIC ACID ESTERS KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14662478?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessing+Human+Exposure+to+Phthalates+Using+Monoesters+and+Their+Oxidized+Metabolites+as+Biomarkers&rft.au=Barr%2C+Dana+B%3BSilva%2C+Manori+J%3BKato%2C+Kayoko%3BReidy%2C+John+A%3BMalek%2C+Nicole+A%3BHurtz%2C+Donald%3BSadowski%2C+Melissa&rft.aulast=Barr&rft.aufirst=Dana&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1148&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOLOGICAL INDICATORS; METABOLIC ACTIVATION; PHTHALIC ACID ESTERS; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - On the Relationship Between Time-Series Studies, Dynamic Population Studies, and Estimating Loss of Life Due to Short-Term Exposure to Environmental Risks AN - 14661206; 10647122 JF - Environmental Health Perspectives AU - Burnett, Richard T AU - Dewanji, Anup AU - Dominici, Francesca AU - Goldberg, Mark S AU - Cohen, Aaron AU - Krewski, Daniel Y1 - 2003/07// PY - 2003 DA - Jul 2003 SP - 1170 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - MATHEMATIC MODELS, POPULATION KW - POPULATION DYNAMICS KW - MORTALITY PATTERNS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14661206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=On+the+Relationship+Between+Time-Series+Studies%2C+Dynamic+Population+Studies%2C+and+Estimating+Loss+of+Life+Due+to+Short-Term+Exposure+to+Environmental+Risks&rft.au=Burnett%2C+Richard+T%3BDewanji%2C+Anup%3BDominici%2C+Francesca%3BGoldberg%2C+Mark+S%3BCohen%2C+Aaron%3BKrewski%2C+Daniel&rft.aulast=Burnett&rft.aufirst=Richard&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1170&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 43 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; POPULATION DYNAMICS; MATHEMATIC MODELS, POPULATION; MORTALITY PATTERNS ER - TY - JOUR T1 - The effect of abrupt shifts in temperature on the lag phase duration of Escherichia coli and Klebsiella oxytoca. AN - 73264693; 12745234 AB - The effect of temperature of incubation on lag times of two gram-negative foodborne bacteria was investigated. Bacteria were instantaneously transferred between temperatures within and beyond the normal physiological temperature range (NPTR). Abrupt temperature shifts induced lag phases, but the degree of the response was dependent on the direction and magnitude of the shift. Temperature downshifts induced larger relative lag times (RLT; the ratio of lag time to generation time), than equivalent upshifts. The hypothesis of Robinson et al. [Int. J. Food Microbiol. 44 (1998) 83] that lag time can be understood in terms of the amount of work to be done to adjust to new environmental conditions and the rate at which that work is done was supported. Deviation of the reported proportionality between lag time and generation time was observed when late-exponential phase cells were subjected to abrupt temperature shifts from beyond the normal physiological range. JF - International journal of food microbiology AU - Mellefont, L A AU - Ross, T AD - Centre for Food Safety and Quality, School of Agricultural Science, University of Tasmania, GPO Box 252-54, Hobart 7001, Tasmania, Australia. Lyndal.Mellefont@utas.edu.au Y1 - 2003/06/25/ PY - 2003 DA - 2003 Jun 25 SP - 295 EP - 305 VL - 83 IS - 3 SN - 0168-1605, 0168-1605 KW - Index Medicus KW - Food Microbiology KW - Kinetics KW - Temperature KW - Klebsiella oxytoca -- growth & development KW - Escherichia coli -- growth & development KW - Models, Biological UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73264693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+food+microbiology&rft.atitle=The+effect+of+abrupt+shifts+in+temperature+on+the+lag+phase+duration+of+Escherichia+coli+and+Klebsiella+oxytoca.&rft.au=Mellefont%2C+L+A%3BRoss%2C+T&rft.aulast=Mellefont&rft.aufirst=L&rft.date=2003-06-25&rft.volume=83&rft.issue=3&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=International+journal+of+food+microbiology&rft.issn=01681605&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-09-22 N1 - Date created - 2003-05-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Nuclear Weapons in Russia: Safety, Security, and Control Issues [Includes Table] AN - 1679129037; WM00592 AB - Discusses issues related to accounting for and maintaining control over nuclear weapons in Russia following the collapse of the Soviet Union; overviews U.S. and international programs designed to facilitate the safekeeping of Russian nuclear weapons. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2003 SP - 20 KW - Arms control KW - Command and control KW - Government appropriations and expenditures KW - Nuclear weapons security KW - Russia-United States relations KW - Russian nuclear program KW - Soviet Union KW - Terrorism KW - Nunn, Sam KW - Lugar, Richard G. KW - Nunn, Sam KW - Lugar, Richard G. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679129037?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_wm&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Nuclear+Weapons+in+Russia%3A+Safety%2C+Security%2C+and+Control+Issues+%5BIncludes+Table%5D&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2003-06-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - Russia. Ministry for Atomic Energy; United States. Department of Defense; United States. Department of Energy N1 - Analyte descriptor - NSA document type: Issue Brief N1 - People - Lugar, Richard G.; Nunn, Sam N1 - Last updated - 2015-06-16 ER - TY - GEN T1 - Iran's Ballistic Missile Capabilities [Includes Tables; Best Available Copy] AN - 1679128674; WM00591 AB - Reports inventory of missiles believed to be held in Iran, describing the capabilities and origins of each. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2003 SP - 6 KW - Arms transfers KW - Ballistic missiles KW - China KW - Iran KW - Scud Missiles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679128674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_wm&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Iran%27s+Ballistic+Missile+Capabilities+%5BIncludes+Tables%3B+Best+Available+Copy%5D&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2003-06-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Analyte descriptor - NSA document type: Report N1 - Last updated - 2015-06-16 ER - TY - GEN T1 - North Korea's Nuclear Weapons Program AN - 1679128940; WM00590 AB - Summarizes U.S. intelligence on the North Korean nuclear weapons program, including known nuclear facilities and nuclear supplier nations; summarizes U.S. policy reaction to North Korea's resumption of nuclear activities. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2003 SP - 17 KW - Intercontinental ballistic missiles KW - Korea (North)-United States Agreed Framework (1994) KW - Korea (North) nuclear program KW - Nuclear nonproliferation KW - Nuclear Nonproliferation Treaty (1968) KW - Nuclear reactors KW - Pakistani nuclear cooperation KW - Sanctions KW - Soviet nuclear cooperation KW - Carter, Jimmy KW - Kim Chong Il KW - Gallucci, Robert L. KW - Bush, George W. KW - Kim Il Sung KW - Rumsfeld, Donald H. KW - Carter, Jimmy KW - Kim Chong Il KW - Gallucci, Robert L. KW - Bush, George W. KW - Kim Il Sung KW - Rumsfeld, Donald H. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679128940?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_wm&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=North+Korea%27s+Nuclear+Weapons+Program&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2003-06-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - Asia-Pacific Economic Cooperation; Korean Peninsula Energy Development Organization N1 - Analyte descriptor - NSA document type: Issue Brief N1 - People - Bush, George W.; Carter, Jimmy; Gallucci, Robert L.; Kim Chong Il; Kim Il Sung; Rumsfeld, Donald H. N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - Application of comprehensive two-dimensional gas chromatography to drugs analysis in doping control. AN - 73497303; 12877168 AB - Comprehensive two-dimensional gas chromatography (GC x GC) now occupies a niche within the GC technology regime. The technique is undeniably unique in the manner in which the experiment is conducted, the way results are presented and the interpretive opportunities offered. For the 1000th volume of this journal it is appropriate to expand upon these features, and review the progress made in GC x GC to date. Firstly, brief general comment is made on multidimensional procedures, and to review key aspects of GC x GC. The use of the targeted multidimensional GC method allows absolute retentions in the second dimension of a GC x GC experiment to be estimated, and also offers a novel way to obtain enhanced response for resolved solutes. Then, to illustrate the utility of the technique, the application of GC x GC to the screening of drugs and their metabolites in biological fluids is described using prolintane metabolites in canine urine as an example, with samples taken at four time intervals after administration. This example illustrates the first application of GC x GC in the field of forensic toxicology, an area traditionally dominated by GC-MS. Most drug compounds were found to be retained on the 0.8-m second column for a greater time than the modulation period (3 s) used for initial analysis, under the conditions described. Hence a 0.4-m D2 BPX50 (50% phenyl methyl polysilphenylene) column was then used throughout, with most compounds retained less than 4 s. For the standard drug mixture, three overlapping drugs on the first dimension column (BPX5) were subsequently baseline resolved on the BPX50 column. For prolintane administration samples, the parent drug and metabolites could be effectively resolved from background matrix peaks. Likewise a 23-drug spike standard in horse urine blank gave acceptable resolution of the drugs from matrix peaks. JF - Journal of chromatography. A AU - Kueh, A J AU - Marriott, P J AU - Wynne, P M AU - Vine, J H AD - Australian Centre for Research on Separation Science, Department of Applied Chemistry, RMIT University, GPO Box 2476V, Melbourne, Vic. 3001, Australia. Y1 - 2003/06/06/ PY - 2003 DA - 2003 Jun 06 SP - 109 EP - 124 VL - 1000 IS - 1-2 SN - 0021-9673, 0021-9673 KW - Index Medicus KW - Sensitivity and Specificity KW - Humans KW - Calibration KW - Doping in Sports KW - Chromatography, Gas -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/73497303?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chromatography.+A&rft.atitle=Application+of+comprehensive+two-dimensional+gas+chromatography+to+drugs+analysis+in+doping+control.&rft.au=Kueh%2C+A+J%3BMarriott%2C+P+J%3BWynne%2C+P+M%3BVine%2C+J+H&rft.aulast=Kueh&rft.aufirst=A&rft.date=2003-06-06&rft.volume=1000&rft.issue=1-2&rft.spage=109&rft.isbn=&rft.btitle=&rft.title=Journal+of+chromatography.+A&rft.issn=00219673&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-08-26 N1 - Date created - 2003-07-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Safety and immunogenicity of an oral, inactivated enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine in Bangladeshi children 18-36 months of age. AN - 73274798; 12744870 AB - A phase II safety and immunogenicity study of an oral-formalin inactivated enterotoxigenic Escherichia coli (ETEC) vaccine containing six colonization factors (CFA/I, CS1, CS2, CS3, CS4, CS5) and 1mg of recombinant cholera toxin B subunit (the CF-BS-ETEC vaccine) was carried out in an urban slum of Dhaka city in Bangladesh. The study was carried out in a double blinded, placebo controlled design in 158 children, 18-36 months of age. Children were given two doses of the CF-BS-ETEC vaccine or the placebo which consisted of E. coli K12. The vaccine was well tolerated. The immune response was studied in 60 children (30 each in the placebo and vaccine group). Significant vaccine specific IgA antibody-secreting cell (ASC) responses were seen 7 days after ingestion of the first and second dose of the vaccine. The responses to CFA/I (PGovernment Printing Office VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - genetically modified foods KW - man KW - suicide genes KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts; Toxicology Abstracts; Bioengineering Abstracts KW - X 24120:Food, additives & contaminants KW - W4 330:Biopolymers & Food Biotechnology KW - W 30965:Miscellaneous, Reviews KW - F 06844:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18828628?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Introduction%3A+What+Are+the+Issues+in+Addressing+the+Allergenic+Potential+of+Genetically+Modified+Foods%3F&rft.au=Metcalfe%2C+D+D&rft.aulast=Metcalfe&rft.aufirst=D&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5810 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.5810 ER - TY - JOUR T1 - A Critical Review of Methods for Comparing Estrogenic Activity of Endogenous and Exogenous Chemicals in Human Milk and Infant Formula AN - 18828036; 5714967 AB - The two primary sources of nutrition for infants are human milk and infant formula. Both contain an array of endogenous and exogenous chemicals that may act through many separate hormonal mechanisms. The safety of infant nutrition sources has been questioned based on the possibility that exogenous chemicals may exert adverse effects on nursing or formula-fed infants through estrogen-mediated mechanisms. In response to these and other concerns, the National Research Council recommended assessing the estrogenic potency of natural and anthropogenic hormonally active agents. Furthermore, the Endocrine Disruptor Screening and Testing Advisory Committee of the U.S. Environmental Protection Agency specifically recommended testing chemicals present in human milk as a representative mixture to which large segments of the population are exposed. To date, no clinical or epidemiologic evidence demonstrates that levels of chemicals currently found in human milk or infant formulas cause adverse effects in infants. Nonetheless, the question is sufficiently important to warrant a consideration of how best to evaluate potential estrogenic risks. We reviewed the types of data available for measuring estrogenic potency as well as methods for estimating health risks from mixtures of chemicals in infant nutrition sources that act via estrogenic mechanisms. We conclude that the science is insufficiently developed at this time to allow a credible assessment of health risks to infants based on estimates of estrogenic potency or on an understanding of toxicologic effects mediated by estrogenic mechanisms. However, clinical and epidemiologic data for infant nutrition sources may provide insights about risks of such substances in human milk and infant formulas. JF - Environmental Health Perspectives AU - Borgert, C J AU - LaKind, J S AU - Witorsch, R J AD - 238 Turkey Creek, 10514 Palmetto Blvd., Alachua, FL 32615, USA, cjborgert@apt-pharmatox.com Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1020 EP - 1036 PB - NIH, Government Printing Office VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - estrogenic activity KW - infant formulas KW - man KW - Toxicology Abstracts KW - X 24221:Toxicity testing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18828036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Critical+Review+of+Methods+for+Comparing+Estrogenic+Activity+of+Endogenous+and+Exogenous+Chemicals+in+Human+Milk+and+Infant+Formula&rft.au=Borgert%2C+C+J%3BLaKind%2C+J+S%3BWitorsch%2C+R+J&rft.aulast=Borgert&rft.aufirst=C&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1020&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.6023 ER - TY - JOUR T1 - Assessment of Allergenic Potential of Genetically Modified Foods: An Agenda for Future Research AN - 18824443; 5715025 AB - Speakers and participants in the workshop "Assessment of the Allergenic Potential of Genetically Modified Foods" met in breakout groups to discuss a number of issues including needs for future research. These groups agreed that research should progress quickly in the area of hazard identification and that a need exists for more basic research to understand the mechanisms underlying food allergy. A list of research needs was developed. JF - Environmental Health Perspectives AU - Selgrade, M-JK AU - Kimber, I AU - Goldman, L AU - Germolec AD - MD-B143-04, U.S. EPA, Research Triangle Park, NC 27711, USA, selgrade.maryjane@epa.gov Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1140 EP - 1141 PB - NIH, Government Printing Office VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - future research KW - genetically modified foods KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts; Toxicology Abstracts; Bioengineering Abstracts KW - X 24120:Food, additives & contaminants KW - W4 330:Biopolymers & Food Biotechnology KW - W 30965:Miscellaneous, Reviews KW - F 06844:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18824443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Allergenic+Potential+of+Genetically+Modified+Foods%3A+An+Agenda+for+Future+Research&rft.au=Selgrade%2C+M-JK%3BKimber%2C+I%3BGoldman%2C+L%3BGermolec&rft.aulast=Selgrade&rft.aufirst=M-JK&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1140&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5815 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.5815 ER - TY - JOUR T1 - Assessment of Protein Allergenicity on the Basis of Immune Reactivity: Animal Models AN - 18823931; 5715023 AB - Because of the public concern surrounding the issue of the safety of genetically modified organisms, it is critical to have appropriate methodologies to aid investigators in identifying potential hazards associated with consumption of foods produced with these materials. A recent panel of experts convened by the Food and Agriculture Organization and World Health Organization suggested there is scientific evidence that using data from animal studies will contribute important information regarding the allergenicity of foods derived from biotechnology. This view has given further impetus to the development of suitable animal models for allergenicity assessment. This article is a review of what has been achieved and what still has to be accomplished regarding several different animal models. Progress made in the design and evaluation of models in the rat, the mouse, the dog and in swine is reviewed and discussed. JF - Environmental Health Perspectives AU - Kimber, I AU - Dearman, R J AU - Penninks, AH AU - Knippels, LMJ AU - Buchanan, R B AU - Hammerberg, B AU - Jackson, HA AU - Helm, R M AD - Syngenta Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire SK10 4TJ, UK, ian.kimber@syngenta.com Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1125 EP - 1130 PB - NIH, Government Printing Office VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - genetically modified foods KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts; Toxicology Abstracts; Bioengineering Abstracts KW - X 24120:Food, additives & contaminants KW - W4 330:Biopolymers & Food Biotechnology KW - W 30965:Miscellaneous, Reviews KW - F 06844:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18823931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Protein+Allergenicity+on+the+Basis+of+Immune+Reactivity%3A+Animal+Models&rft.au=Kimber%2C+I%3BDearman%2C+R+J%3BPenninks%2C+AH%3BKnippels%2C+LMJ%3BBuchanan%2C+R+B%3BHammerberg%2C+B%3BJackson%2C+HA%3BHelm%2C+R+M&rft.aulast=Kimber&rft.aufirst=I&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1125&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5813 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.5813 ER - TY - JOUR T1 - Large Effects from Small Exposures. I. Mechanisms for Endocrine-Disrupting Chemicals with Estrogenic Activity AN - 18821967; 5714965 AB - Information concerning the fundamental mechanisms of action of both natural and environmental hormones, combined with information concerning endogenous hormone concentrations, reveals how endocrine-disrupting chemicals with estrogenic activity (EEDCs) can be active at concentrations far below those currently being tested in toxicological studies. Using only very high doses in toxicological studies of EEDCs thus can dramatically underestimate bioactivity. Specifically: a) The hormonal action mechanisms and the physiology of delivery of EEDCs predict with accuracy the low-dose ranges of biological activity, which have been missed by traditional toxicological testing. b) Toxicology assumes that it is valid to extrapolate linearly from high doses over a very wide dose range to predict responses at doses within the physiological range of receptor occupancy for an EEDC; however, because receptor-mediated responses saturate, this assumption is invalid. c) Furthermore, receptor-mediated responses can first increase and then decrease as dose increases, contradicting the assumption that dose-response relationships are monotonic. d) Exogenous estrogens modulate a system that is physiologically active and thus is already above threshold, contradicting the traditional toxicological assumption of thresholds for endocrine responses to EEDCs. These four fundamental issues are problematic for risk assessment methods used by regulatory agencies, because they challenge the traditional use of extrapolation from high-dose testing to predict responses at the much lower environmentally relevant doses. These doses are within the range of current exposures to numerous chemicals in wildlife and humans. These problems are exacerbated by the fact that the type of positive and negative controls appropriate to the study of endocrine responses are not part of traditional toxicological testing and are frequently omitted, or when present, have been misinterpreted. JF - Environmental Health Perspectives AU - Welshons, W V AU - Thayer, KA AU - Judy, B M AU - Taylor, JA AU - Curran, E M AU - Vom Saal, FS AD - Dept. of Veterinary Biomedical Sciences, E102 Veterinary Medicine, University of Missouri-Columbia, Columbia, MO 65211, USA, welshonsw@missouri.edu Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 994 EP - 1006 PB - NIH, Government Printing Office VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - endocrine disruptors KW - estrogenic activity KW - mechanisms KW - Toxicology Abstracts KW - X 24240:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18821967?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Large+Effects+from+Small+Exposures.+I.+Mechanisms+for+Endocrine-Disrupting+Chemicals+with+Estrogenic+Activity&rft.au=Welshons%2C+W+V%3BThayer%2C+KA%3BJudy%2C+B+M%3BTaylor%2C+JA%3BCurran%2C+E+M%3BVom+Saal%2C+FS&rft.aulast=Welshons&rft.aufirst=W&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=994&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5494 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.5494 ER - TY - JOUR T1 - Protein Digestibility and Relevance to Allergenicity AN - 18820471; 5715022 AB - In January 2001 a joint Food and Agriculture Organization of the United Nations/World Health Organization Expert Consultation Committee on Allergenicity of Foods Derived from Biotechnology published a report outlining in detail an approach for assessing the allergenic potential of novel proteins. One component of this decision tree is a determination of whether the protein of interest is resistant to proteolysic digestion. Although these in vitro methodologies have been useful, the correlation between resistance to proteolysis and allergenic activity is not absolute. Two views and highlights of supporting research regarding the relationship of resistance to digestion and allergenicity are presented in this article. JF - Environmental Health Perspectives AU - Bannon, G AU - Fu, T-J AU - Kimber, I AU - Hinton, D M AD - U.S. FDA, 8301 Muirkirk Rd., Laurel, MD 20878-2476, USA, dmhinton@cfsan.fda.gov Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1122 EP - 1124 PB - NIH, Government Printing Office VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - digestibility KW - man KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts; Toxicology Abstracts; Bioengineering Abstracts KW - X 24120:Food, additives & contaminants KW - W4 330:Biopolymers & Food Biotechnology KW - W 30965:Miscellaneous, Reviews KW - F 06844:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18820471?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Protein+Digestibility+and+Relevance+to+Allergenicity&rft.au=Bannon%2C+G%3BFu%2C+T-J%3BKimber%2C+I%3BHinton%2C+D+M&rft.aulast=Bannon&rft.aufirst=G&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1122&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5812 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1289/ehp.5812 ER - TY - JOUR T1 - Rapid Detection of vanA and vanB Genes Directly from Clinical Specimens and Enrichment Broths by Real-Time Multiplex PCR Assay AN - 18810216; 5684713 AB - A real-time PCR assay previously developed for use on the Roche LightCycler platform was investigated as an alternative to culture for the direct detection of vancomycin-resistant enterococci (VRE) in clinical specimens. PCR primers and fluorescence resonance energy transfer hybridization probes specific for the vanA and vanB genes were combined in a multiplex real-time PCR assay performed directly with fecal material obtained by rectal swabbing and with enrichment broth samples. DNA was prepared from the rectal swabs and enrichment broths with a commercially available DNA preparation column designed specifically for use with fecal specimens. One hundred eighty duplicate rectal swabs were obtained from 42 patients who were previously found to be positive for VRE and who were being monitored for carriage of VRE. Direct and enrichment broth cultures were performed with one swab, while PCR was performed with the other swab as well as any corresponding presumptive positive enrichment broth. In total, 100 specimens from 30 patients remained positive for VRE by at least one method. The multiplex real-time PCR was positive for 88 enrichment broths of rectal swabs from 27 patients but for only 45 rectal swabs from 15 patients. Direct culture was positive for VRE for only 43 specimens from 11 patients, while enrichment broth culture was positive for VRE for 75 specimens from 22 patients. Inhibition studies for the multiplex real-time PCR assay, performed by spiking the DNA extracts from 50 negative rectal swabs and the corresponding enrichment broths with between 1 and 10 CFU of a VanB Enterococcus faecium strain, detected inhibition rates of 55.1 and 10%, respectively. PCR performed directly with enrichment broths was found to be significantly more sensitive than enrichment broth culture (P < 0.025). Negative samples were identified significantly earlier by PCR than by culture alone. JF - Journal of Clinical Microbiology AU - Palladino, S AU - Kay, I D AU - Flexman, J P AU - Boehm, I AU - Costa, AMG AU - Lambert, E J AU - Christiansen, K J AD - Department of Microbiology & Infectious Diseases, Royal Perth Hospital, Box X2213 GPO, Perth, Western Australia, 6847, Australia, silvano.palladino@health.wa.gov.au Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 2483 EP - 2486 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 41 IS - 6 SN - 0095-1137, 0095-1137 KW - enrichment broth culture KW - vanA gene KW - vanB gene KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - A 01116:Bacteria KW - J 02704:Enumeration UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18810216?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Rapid+Detection+of+vanA+and+vanB+Genes+Directly+from+Clinical+Specimens+and+Enrichment+Broths+by+Real-Time+Multiplex+PCR+Assay&rft.au=Palladino%2C+S%3BKay%2C+I+D%3BFlexman%2C+J+P%3BBoehm%2C+I%3BCosta%2C+AMG%3BLambert%2C+E+J%3BChristiansen%2C+K+J&rft.aulast=Palladino&rft.aufirst=S&rft.date=2003-06-01&rft.volume=41&rft.issue=6&rft.spage=2483&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.41.6.2483-2486.2003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1128/JCM.41.6.2483-2486.2003 ER - TY - JOUR T1 - Decomposition of vegetation cover into woody and herbaceous components using AVHRR NDVI time series AN - 18805437; 5665342 AB - A method is developed to separate Normalised Difference Vegetation Index (NDVI) time series data into contributions from woody (perennial) and herbaceous (annual) vegetation, and thereby to infer their separate leaf area indices and cover fractions. The method is formally consistent with fundamental linearity requirements for such a decomposition, and is capable of rejecting contaminated NDVI data. In this study, estimates of annual averaged woody cover and monthly averaged herbaceous cover over Australia are determined using Pathfinder AVHRR Land series (PAL) Global Area Coverage (GAC) Advanced Very High Resolution Radiometer (AVHRR) NDVI data from 1981 to 1994, together with ground-based measurements of leaf area index (LAI) and foliage projective cover (FPC). JF - Remote Sensing of Environment AU - Lu, H AU - Raupach, M R AU - McVicar, T R AU - Barrett, D J AD - CSIRO Land and Water, Canberra Laboratory (Bulter), GPO Box 1666, Canberra ACT 2601, Australia, hua.lu@csiro.au Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1 EP - 18 PB - Elsevier Science Inc., Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 86 IS - 1 SN - 0034-4257, 0034-4257 KW - herbaceous plants KW - woody plants KW - Ecology Abstracts KW - D 04100:Terrestrial ecosystems - general KW - D 04002:Surveying and remote sensing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18805437?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Remote+Sensing+of+Environment&rft.atitle=Decomposition+of+vegetation+cover+into+woody+and+herbaceous+components+using+AVHRR+NDVI+time+series&rft.au=Lu%2C+H%3BRaupach%2C+M+R%3BMcVicar%2C+T+R%3BBarrett%2C+D+J&rft.aulast=Lu&rft.aufirst=H&rft.date=2003-06-01&rft.volume=86&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Remote+Sensing+of+Environment&rft.issn=00344257&rft_id=info:doi/10.1016%2FS0034-4257%2803%2900054-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/S0034-4257(03)00054-3 ER - TY - JOUR T1 - Influence of patch characteristics on browsing of tree seedlings by mammalian herbivores AN - 18802016; 5662564 AB - 1. In south-eastern Australia, browsing of commercial tree seedlings by mammalian herbivores in plantation forestry incurs a large economic cost to the industry, through its effect on tree survival, growth and form. In the absence of lethal methods to control herbivore populations, appropriate manipulation of vegetation through silvicultural management may reduce browsing but it relies on understanding the feeding responses of the herbivores to such changes. 2. We evaluated the extent to which vegetation patch characteristics affected browsing of pine Pinus radiata seedlings by generalist mammalian herbivores, including redbellied pademelons Thylogale billardierii, Bennett's wallaby Macropus rufogriseus rufogriseus and the common brushtail possum Trichosurus vulpecula. 3. In field trials, browsing of pine seedlings was greatest when they were located in patches of high quality, i.e. palatable short vegetation (grass), intermediate in high-quality tall vegetation (Lomandra longifolia) and least in low-quality tall vegetation (bracken and shrub). Patch structure also affected browsing: in low-quality patches pine seedlings were browsed more in short vegetation patches (12-24 cm shorter than the seedling) than in tall vegetation patches (at least as tall as the seedling). This difference was at least partly because herbivores took, on average, 2 weeks longer to locate seedlings in tall than in short vegetation. 4. In trials with captive red-bellied pademelons and brushtail possums, pine seedlings were browsed similarly in small short grass and soil patches. However, when these patches were large and spatially separated, they were browsed more in short grass than soil patches. Selection at the patch or individual plant level therefore depended on spatial scale and proximity of the patches. 5. Synthesis and applications. The influence of patch characteristics on browsing has the potential to be exploited for the management of browsing damage to commercially important tree seedlings in forestry plantations. Retention of relatively tall vegetation, particularly if it is unpalatable, in areas at risk of heavy browsing, for example by delaying the use of herbicide, may be a useful management strategy for reducing browsing. This needs to be weighed against the potential detrimental competitive effects of neighbouring vegetation on the seedlings. JF - Journal of Applied Ecology AU - Pietrzykowski, E AU - McArthur, C AU - Fitzgerald, H AU - Goodwin, AN AD - School of Zoology, University of Tasmania, GPO Box 252-05, Hobart, Tasmania 7001, Australia, Clare.McArthur@utas.edu.au Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 458 EP - 469 VL - 40 IS - 3 SN - 0021-8901, 0021-8901 KW - Brushtail possum KW - Monterey pine KW - Ecology Abstracts KW - D 04700:Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18802016?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Ecology&rft.atitle=Influence+of+patch+characteristics+on+browsing+of+tree+seedlings+by+mammalian+herbivores&rft.au=Pietrzykowski%2C+E%3BMcArthur%2C+C%3BFitzgerald%2C+H%3BGoodwin%2C+AN&rft.aulast=Pietrzykowski&rft.aufirst=E&rft.date=2003-06-01&rft.volume=40&rft.issue=3&rft.spage=458&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Ecology&rft.issn=00218901&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - The relative importance of cattle grazing in subtropical grasslands: does it reduce or enhance plant biodiversity? AN - 18792934; 5662563 AB - 1. Livestock grazing enterprises have potentially threatening effects on the conservation of plants in grassy subtropical eucalypt woodlands. Commercial levels of grazing could cause local extinctions of sensitive native species and/or reductions in abundance and species richness in native pastures. 2. We studied the nature of grazing impacts on the diversity and composition of herbaceous plants and used a natural experiment to analyse the effects of disturbances (cattle grazing, soil disturbance, water enrichment) and environment (lithology, slope position, presence of trees) on plant community composition in eastern Australia. We sampled pastures and reserves at 191 sites over an area of 3000 ha. 3. Canonical correspondence analysis (CCA) was used to explore the relative importance of disturbance and environment in accounting for floristic variation and to examine individual species responses. From individual responses, we identified seven response groups relating to grazing. The factors analysed explained small but significant amounts of floristic variation, and there were interactions between soil disturbance, water enrichment and grazing. 4. We explored the hypothesis that grazing increased species density at small scales but decreased it at landscape scales, due to the elimination of grazing-sensitive species. Our data did not support the hypothesis, as there were similar numbers of species that increase with grazing (increasers) and species that decline with increasing grazing (decreasers) in the assemblage. However, there were more native decreasers and more exotic increasers in the assemblage. 5. Synthesis and applications. For land managers to retain plant diversity on grazed landscapes, it would be desirable to provide all levels of grazing pressure across the landscape, including areas protected from livestock grazing. This would apply to all plant communities where both grazing increasers and decreasers are present. Extensive areas supporting grassland with a tall tussock structure that is selectively grazed are most important, as all plant response groups have some representation and ecosystem function is retained under moderate grazing. In terms of regional conservation planning, the protection and enlargement of areas protected from livestock grazing is important in the study area, as these occur on only about 4% of the landscape and are threatened by on-going disturbances and land-use intensification. JF - Journal of Applied Ecology AU - Mcintyre, S AU - Heard, K M AU - Martin, T G AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra City, ACT 2911, Australia, sue.mcintyre@csiro.au Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 445 EP - 457 VL - 40 IS - 3 SN - 0021-8901, 0021-8901 KW - Ecology Abstracts KW - D 04705:Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18792934?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Ecology&rft.atitle=The+relative+importance+of+cattle+grazing+in+subtropical+grasslands%3A+does+it+reduce+or+enhance+plant+biodiversity%3F&rft.au=Mcintyre%2C+S%3BHeard%2C+K+M%3BMartin%2C+T+G&rft.aulast=Mcintyre&rft.aufirst=S&rft.date=2003-06-01&rft.volume=40&rft.issue=3&rft.spage=445&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Ecology&rft.issn=00218901&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Legionella Reveal Dendritic Cell Functions that Facilitate Selection of Antigens for MHC Class II Presentation AN - 18791334; 5663180 AB - To understand how adaptive immune responses are generated against bacteria that avoid being delivered to lysosomes, interactions between professional antigen-presenting cells (APCs) and the intracellular pathogen Legionella pneumophila were examined. In contrast to murine bone marrow-derived macrophages (BMMs), we show that dendritic cells (DCs) restrict the growth of intracellular Legionella. Similar to what has been reported in BMMs, phagosomes containing Legionella matured into endoplasmic reticulum (ER)- derived organelles after DC internalization. Biogenesis of an ER-derived vacuole did not effectively sequester Legionella antigens from presentation on MHC class II molecules (MHC II). It was determined that proteins synthesized after Legionella had established residence in an ER-derived vacuole were presented by infected APCs. These data indicate that the ability of DCs to restrict intracellular growth of Legionella could be an important property that facilitates priming of protective T cell-mediated immune responses to vacuolar pathogens. JF - Immunity AU - Neild, AL AU - Roy, C R AD - Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA, craig.roy@yale.edu Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 813 EP - 823 VL - 18 IS - 6 SN - 1074-7613, 1074-7613 KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - F 06776:Cell cooperation (antigen presentation) KW - J 02832:Antigenic properties and virulence KW - F 06801:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18791334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Immunity&rft.atitle=Legionella+Reveal+Dendritic+Cell+Functions+that+Facilitate+Selection+of+Antigens+for+MHC+Class+II+Presentation&rft.au=Neild%2C+AL%3BRoy%2C+C+R&rft.aulast=Neild&rft.aufirst=AL&rft.date=2003-06-01&rft.volume=18&rft.issue=6&rft.spage=813&rft.isbn=&rft.btitle=&rft.title=Immunity&rft.issn=10747613&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Synthesis and Localization of the Salmonella SPI-1 Type III Secretion Needle Complex Proteins PrgI and PrgJ AN - 18773005; 5634466 AB - An essential component of type III secretion systems (TTSS) is a supramolecular structure termed the needle complex. In Salmonella enterica, at least four proteins make up this structure: InvG, PrgH, PrgK, and PrgI. Another protein, PrgJ, is thought to play a role in the assembly of this structure, but its function is poorly understood. We have analyzed the expression and localization of PrgJ and the needle protein PrgI in different S. enterica serovar Typhimurium mutant strains. We found that the levels of PrgI and PrgJ were significantly reduced in a TTSS-deficient invA mutant strain and that the decreased levels were due to protein instability. In addition, we found that PrgJ, although associated with the needle complex in wild-type S. enterica serovar Typhimurium, was absent from needle complexes obtained from an invJ mutant strain, which exhibits very long needle substructures. We suggest that PrgJ is involved in capping the needle substructure of the needle complex. JF - Journal of Bacteriology AU - Sukhan, A AU - Kubori, T AU - Galan, JE AD - Section of Microbial Pathogenesis, Yale School of Medicine, 296 Congress Ave., Rm. 354E, New Haven, CT 06536-1418, jorge.galan@yale.edu Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 3480 EP - 3483 VL - 185 IS - 11 SN - 0021-9193, 0021-9193 KW - InvG protein KW - PrgH protein KW - PrgI protein KW - PrgJ protein KW - PrgK protein KW - invJ gene KW - needle proteins KW - secretion system type III KW - Microbiology Abstracts B: Bacteriology; Genetics Abstracts KW - G 07320:Bacterial genetics KW - J 02727:Amino acids, peptides and proteins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18773005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Bacteriology&rft.atitle=Synthesis+and+Localization+of+the+Salmonella+SPI-1+Type+III+Secretion+Needle+Complex+Proteins+PrgI+and+PrgJ&rft.au=Sukhan%2C+A%3BKubori%2C+T%3BGalan%2C+JE&rft.aulast=Sukhan&rft.aufirst=A&rft.date=2003-06-01&rft.volume=185&rft.issue=11&rft.spage=3480&rft.isbn=&rft.btitle=&rft.title=Journal+of+Bacteriology&rft.issn=00219193&rft_id=info:doi/10.1128%2FJB.185.11.3480-3483.2003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1128/JB.185.11.3480-3483.2003 ER - TY - JOUR T1 - Development of an Enzyme-Linked Immunosorbent Assay for the Detection and Quantification of the Insecticide Tebufenozide in Wine AN - 17823499; 6101359 AB - A CD-ELISA assay has been developed for the quantification of the insecticide tebufenozide in red and white wine. Polyclonal antisera, raised against both KLH- and OVA-linked immunogens of the hapten 1-tert-butyl-2-[4-(carboxypropan-3-yl)benzoyl]-1-(3,5-dimethyl benzoyl)hydrazide NHS ester (Ib) were trialled for use in a quantitative immunoassay and both were found to be suitable for use, with IC sub(50) values in the vicinity of 10 mu g L super(-1) regardless of the carrier protein used and matrix (red versus white wine). The limits of detection were 0.7 mu g L super(-1) and 3 mu g L super(-1) for OVA- and KLH-linked polyclonal sera, respectively. In both cases, the IgG fraction isolated from the antisera was highly specific for tebufenozide and its hapten derivatives, showing no detectable cross-reactivity with eleven other potential pesticide contaminants used in the wine-making industry. Spiked red and white wine samples were successfully analyzed over the range 10-1000 mu g L super(-1) using the immunoassay developed with IgG isolated from the antiserum rabbit anti-OVA-Ib as the immobilized capture antibody. Reported maximum residue limits for wine are 100 mu g L super(-1) and thus would be readily detected using this technique. The immunoassay format represents a cost-effective, relatively simple means of screening large numbers of samples for the presence of this insecticide. JF - Food and Agricultural Immunology AU - Irwin, JA AU - Tolhurst, R AU - Jackson, P AU - Gale, K R AD - CSIRO Division of Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, Jenny.Irwin@csiro.au Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 93 EP - 104 VL - 15 IS - 2 SN - 0954-0105, 0954-0105 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Immunology Abstracts KW - Cross-reactivity KW - Haptens KW - tebufenozide KW - Insecticides KW - Wine KW - Enzyme-linked immunosorbent assay KW - Esters KW - Antisera KW - Pesticides KW - Immunoglobulin G KW - Contaminants KW - F 06704:Immunoassays KW - W4 330:Biopolymers & Food Biotechnology KW - W 30965:Miscellaneous, Reviews KW - W2 32240:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17823499?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+and+Agricultural+Immunology&rft.atitle=Development+of+an+Enzyme-Linked+Immunosorbent+Assay+for+the+Detection+and+Quantification+of+the+Insecticide+Tebufenozide+in+Wine&rft.au=Irwin%2C+JA%3BTolhurst%2C+R%3BJackson%2C+P%3BGale%2C+K+R&rft.aulast=Irwin&rft.aufirst=JA&rft.date=2003-06-01&rft.volume=15&rft.issue=2&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=Food+and+Agricultural+Immunology&rft.issn=09540105&rft_id=info:doi/10.1080%2F09540100400003188 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Wine; tebufenozide; Insecticides; Antisera; Haptens; Immunoglobulin G; Cross-reactivity; Esters; Contaminants; Enzyme-linked immunosorbent assay; Pesticides DO - http://dx.doi.org/10.1080/09540100400003188 ER - TY - JOUR T1 - Qualitative Responses of Children to Environmental Noise AN - 17588623; 6468504 AB - Results from recent quantitative research consistently demonstrate that children are a high risk group, vulnerable to the adverse effects of noise exposure, especially effects on cognitive performance, motivation and annoyance. The aims of the two qualitative studies reported in this paper are to explore children's a) perception of noise exposure; b) perceived risk of and attitudes towards noise pollution; c) coping strategies; and d) the annoyance response. The Millennium Conference Study involved focus group interviews with an international sample (n = 36) unselected by exposure. The West London Schools Study involved individual interviews, conducted with a purposively selected sample (n = 18) exposed to aircraft noise. The children in the focus groups reported being most affected by neighbours' noise and road traffic noise, whereas children exposed to aircraft noise were most affected by aircraft noise. As expected, the impact of noise pollution on everyday activities (e.g. schoolwork, homework and playing) was larger for the children exposed to high levels of aircraft noise compared with the low noise exposed children and focus group samples. The range of coping strategies that children employed to combat noise exposure in their lives was dependent upon the amount of control they had over the noise source. The emotional response of children describing the annoyance reaction to noise was consistent with adult reactions and it would seem that child noise annoyance is the same construct. Future research should employ qualitative methods to supplement quantitative investigations. JF - Noise and Health AU - Haines, M M AU - Brentnall, S L AU - Stansfeld, SA AU - Klineberg, E AD - Health Risk Management, Pricewaterhouse Coopers, 201 Sussex Street, GPO Box 2650, Sydney, NSW, 1171, Australia, mary.haines@au.pwcglobal.com Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 19 EP - 30 VL - 5 IS - 19 SN - 1463-1741, 1463-1741 KW - Pollution Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Psychology KW - Aircraft noise KW - Schools KW - Cognitive ability KW - Perception KW - Risk assessment KW - British Isles, England, Greater London, London KW - Pollution effects KW - Transportation noise KW - Noise pollution KW - Children KW - Behavior KW - Side effects KW - P 7000:NOISE KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17588623?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Noise+and+Health&rft.atitle=Qualitative+Responses+of+Children+to+Environmental+Noise&rft.au=Haines%2C+M+M%3BBrentnall%2C+S+L%3BStansfeld%2C+SA%3BKlineberg%2C+E&rft.aulast=Haines&rft.aufirst=M&rft.date=2003-06-01&rft.volume=5&rft.issue=19&rft.spage=19&rft.isbn=&rft.btitle=&rft.title=Noise+and+Health&rft.issn=14631741&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - British Isles, England, Greater London, London; Children; Noise pollution; Side effects; Perception; Cognitive ability; Transportation noise; Schools; Psychology; Behavior; Aircraft noise; Risk assessment; Pollution effects ER - TY - JOUR T1 - Chlorination By-Products in Drinking Water and Menstrual Cycle Function AN - 14666160; 10645644 AB - Data from the Women's Reproductive Health Study conducted in California were examined to determine whether exposure to trihalomethanes were associated with reproductive endpoints. Specifically, menstrual characteristics were determined and related to exposure to trihalomethanes via drinking water. A consistent reduction in menstrual cycle length with greater estimated exposure to chlorination byproducts was found, along with a corresponding reduction in follicular, but not luteal, phase length. A significant decrement in menstrual cycle length was associated with increasing brominated trihalomethane concentration and with total trihalomethane as a continuous measure. A shorter follicular phase would reflect earlier ovulation, potentially affecting oocyte maturation, endometrial thickening, and conception or contraception timing. JF - Environmental Health Perspectives AU - Windham, Gayle C AU - Waller, Kirsten AU - Anderson, Meredith AU - Fenster, Laura AU - Mendola, Pauline AU - Swan, Shanna Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 935 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - REPRODUCTION, HUMAN KW - HORMONAL EFFECTS KW - WATER, DRINKING KW - DISINFECTION KW - TRIHALOMETHANE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14666160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Chlorination+By-Products+in+Drinking+Water+and+Menstrual+Cycle+Function&rft.au=Windham%2C+Gayle+C%3BWaller%2C+Kirsten%3BAnderson%2C+Meredith%3BFenster%2C+Laura%3BMendola%2C+Pauline%3BSwan%2C+Shanna&rft.aulast=Windham&rft.aufirst=Gayle&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=935&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - REPRODUCTION, HUMAN; HORMONAL EFFECTS; DISINFECTION; WATER, DRINKING; TRIHALOMETHANE ER - TY - JOUR T1 - The U.S. Environmental Protection Agency Particulate Matter Health Effects Research Centers Program: a Midcourse Report of Status, Progress, and Plans AN - 14663944; 10645890 AB - In the summer of 1999, EPA awarded five center grants for particulate matter (PM) health effects research, which included the University of California Los Angeles, Harvard University, New York University, the University of Rochester, and the University of Washington. A synopsis is provided of the centers' research accomplishments to date in the following categories: the biological mechanisms for PM health effects, the acute health effects of PM exposures, the chronic effects of PM exposures, dosimetry, exposure assessment, and coordination of research within the PM centers program. Both the short- and long-term goals in each of the research areas are elucidated. JF - Environmental Health Perspectives AU - Lippmann, Morton AU - Frampton, Mark AU - Schwartz, Joel AU - Dockery, Douglas AU - Schlesinger, Richard AU - Koutrakis, Petros AU - Froines, John Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1074 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSIMETRY KW - AIR POLLUTION EFFECTS KW - PUBLIC HEALTH KW - AIR POLLUTION RESEARCH KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663944?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+U.S.+Environmental+Protection+Agency+Particulate+Matter+Health+Effects+Research+Centers+Program%3A+a+Midcourse+Report+of+Status%2C+Progress%2C+and+Plans&rft.au=Lippmann%2C+Morton%3BFrampton%2C+Mark%3BSchwartz%2C+Joel%3BDockery%2C+Douglas%3BSchlesinger%2C+Richard%3BKoutrakis%2C+Petros%3BFroines%2C+John&rft.aulast=Lippmann&rft.aufirst=Morton&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1074&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSIMETRY; AIR POLLUTION EFFECTS; PUBLIC HEALTH; AIR POLLUTION RESEARCH; PARTICULATES ER - TY - JOUR T1 - Etiology and Pathogenesis of Uterine Leiomyomas: a Review AN - 14663893; 10645887 AB - Uterine leiomyomas are the most common tumors in women in the US, but little attention has been paid to the causation and pathogenesis of the fibroids until recently, due to the rarity of their malignant transformation. Although the cause or causes of fibroids are unknown, risk factors associated with leiomyomas are reviewed, including: early menarche, parity, age, menopause, obesity, diet, exercise, race, geography, smoking, oral contraceptives, hormone replacement therapy, tamoxifen, and xenoestrogens. Selected theories are provided on the initiation of fibroid tumorigenesis, and the occurrence of genetic aberrations in fibroid tumors is considered, as is evidence for the role of estrogen and progesterone and of growth factors and their receptors. JF - Environmental Health Perspectives AU - Flake, Gordon P AU - Andersen, Janet AU - Dixon, Darlene Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1037 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - DISEASES AND DISORDERS KW - PATHOLOGY, HUMAN KW - TUMORIGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Etiology+and+Pathogenesis+of+Uterine+Leiomyomas%3A+a+Review&rft.au=Flake%2C+Gordon+P%3BAndersen%2C+Janet%3BDixon%2C+Darlene&rft.aulast=Flake&rft.aufirst=Gordon&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1037&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; PATHOLOGY, HUMAN; DISEASES AND DISORDERS; TUMORIGENIC AGENTS ER - TY - JOUR T1 - World Trade Center Fine Particulate Matter Causes Respiratory Tract Hyperresponsiveness in Mice AN - 14663566; 10645650 AB - Fine particulate matter samples were collected in the vicinity of the World Trade Center in New York City following the terrorist attack in September 2001, and the toxicity of samples of PM sub(2.5) was compared with previously tested PM sub(2.5) samples in mice. A doseresponse study was conducted, and an acute inhalation exposure study was performed on one sample. In addition, a short-term time-course study was undertaken to compare aspirated samples from seven different locations with each other and with a standard PM sub(2.5) sample. In all considerations, the ability of the samples to affect respiratory tract responsiveness to aerosolized methacholine was determined. A pooled sample of PM sub(2.5) composed of roughly equivalent amounts of samples from the seven locations caused a mild degree of pulmonary inflammation, but had no effect on parameters of acute lung injury at a dose of 100 mu g aspirated directly into the lungs. Mice exposed to 100 mu g of pooled PM sub(2.5), however, had highly significant increases in airway responsiveness to methacholine aerosol challenge that were significantly greater than those for residual oil flyash. Mice exposed to individual samples from the seven sites exhibited greater lung inflammation than animals exposed to the pooled sample. JF - Environmental Health Perspectives AU - Gavett, Stephen H AU - Haykal-Coates, Najwa AU - Highfill, Jerry W AU - Ledbetter, Allen D AU - Chen, Lung Chi AU - Cohen, Mitchell D AU - Harkema, Jack R Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 981 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PARTICULATES KW - RISK ASSESSMENT KW - DOSE RESPONSE PROFILES KW - PULMONARY EFFECTS KW - PHYSIOLOGICAL RESPONSES, ANIMAL KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663566?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=World+Trade+Center+Fine+Particulate+Matter+Causes+Respiratory+Tract+Hyperresponsiveness+in+Mice&rft.au=Gavett%2C+Stephen+H%3BHaykal-Coates%2C+Najwa%3BHighfill%2C+Jerry+W%3BLedbetter%2C+Allen+D%3BChen%2C+Lung+Chi%3BCohen%2C+Mitchell+D%3BHarkema%2C+Jack+R&rft.aulast=Gavett&rft.aufirst=Stephen&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=981&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 28 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DOSE RESPONSE PROFILES; PULMONARY EFFECTS; PHYSIOLOGICAL RESPONSES, ANIMAL; PARTICULATES; NEW YORK CITY ER - TY - JOUR T1 - Exposure Assessment of Particulate Matter for Susceptible Populations in Seattle AN - 14663086; 10645640 AB - In Seattle, WA, four susceptible study groups-elderly persons who were healthy, had chronic obstructive pulmonary disease (COPD), had coronary heart disease, and children with asthma-were monitored for several seasons to characterize their exposure to particulate matter (PM). During seasons with high and low wood smoke, personal, indoor, and outdoor samples were collected for PM sub(10) and PM sub(2.5). Results indicated that the average personal PM sub(2.5) exposures among the sensitive subpopulations were similar to the mean outdoor concentration but significantly higher than the indoor concentration. Both PM sub(10) and PM sub(2.5) levels were elevated significantly during the heating seasons at all locations, including indoors, outdoors, and around all subjects, but the seasonal variation was more prominent in outdoor levels than in indoor or personal measurements. The COPD and chronic heart disease groups spent more time at home than did the healthy elderly group. Personal PM sub(2.5) exposures varied by study group, with elderly healthy and chronic heart disease subjects having similar exposures, elderly COPD subjects experiencing slightly higher exposures, and asthmatic children having the highest exposures. JF - Environmental Health Perspectives AU - Liu, L-JSally AU - Box, Michael AU - Kalman, David AU - Kaufman, Joel AU - Koenig, Jane AU - Larson, Tim AU - Lumley, Thomas Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 909 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSIMETRY KW - WASHINGTON STATE KW - PULMONARY DISORDERS KW - URBAN ATMOSPHERE KW - PARTICULATES KW - HEART DISEASE KW - AIR POLLUTION, INDOOR KW - SEASONAL COMPARISONS KW - ASTHMA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Exposure+Assessment+of+Particulate+Matter+for+Susceptible+Populations+in+Seattle&rft.au=Liu%2C+L-JSally%3BBox%2C+Michael%3BKalman%2C+David%3BKaufman%2C+Joel%3BKoenig%2C+Jane%3BLarson%2C+Tim%3BLumley%2C+Thomas&rft.aulast=Liu&rft.aufirst=L-JSally&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=909&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSIMETRY; HEART DISEASE; WASHINGTON STATE; AIR POLLUTION, INDOOR; SEASONAL COMPARISONS; ASTHMA; PULMONARY DISORDERS; PARTICULATES; URBAN ATMOSPHERE ER - TY - JOUR T1 - Influence of Airspace Geometry and Surfactant on the Retention of Man-Made Vitreous Fibers (MMVF 10a) AN - 14663052; 10645638 AB - Male Syrian Golden hamsters were exposed to man-made vitreous fibers (MMVF 10a), and the distribution of fibers within the lungs was assessed immediately via electron microscopy. In the conducting airway, almost all fibers were found to be submersed in the aqueous lining layer, while in the alveoli, only about one-third of the fibers were covered completely by lining layer material. The extent of immersion, as assessed in the LangmuirWilhelmy surface balance, demonstrated that immersion of MMVF 10a into the subphase by approximately 50% occurred for fibers shorter than 10 mu m at film surface tensions of 25 mJ/m super(2) and for those 2030 mu m in length at 15 mJ/m super(2). The overall results showed that the geometry and dimension of the airspace and the fibers were important factors for fiber retention. JF - Environmental Health Perspectives AU - Geiser, Marianne AU - Matter, Matthias AU - Maye, Isabelle AU - Im Hof, Vinzenz AU - Gehr, Peter AU - Schurch, Samuel Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 895 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AEROSOLS KW - SURFACTANTS KW - PULMONARY EFFECTS KW - BIOACCUMULATION, HUMAN KW - SYNTHETIC FIBERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663052?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Influence+of+Airspace+Geometry+and+Surfactant+on+the+Retention+of+Man-Made+Vitreous+Fibers+%28MMVF+10a%29&rft.au=Geiser%2C+Marianne%3BMatter%2C+Matthias%3BMaye%2C+Isabelle%3BIm+Hof%2C+Vinzenz%3BGehr%2C+Peter%3BSchurch%2C+Samuel&rft.aulast=Geiser&rft.aufirst=Marianne&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=895&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AEROSOLS; SURFACTANTS; PULMONARY EFFECTS; BIOACCUMULATION, HUMAN; SYNTHETIC FIBERS ER - TY - JOUR T1 - Impact of Metals on the Biodegradation of Organic Pollutants AN - 14663007; 10645891 AB - The presence of metals in the environment can inhibit a broad range of microbial processes, but the effects of metal toxicity on organic pollutant biodegradation in contaminated soil and water environments have not been adequately defined. A review is presented of metal inhibition and toxicity in the context of the biodegradation of co-contaminant organic chemicals. Considered are the effect of medium and soil components on metal bioavailability and toxicity, metal inhibition of aerobic and anaerobic biodegradation, and relationships between metal concentration and biodegradation inhibition. Approaches are also outlined for increasing biodegradation in co-contaminated environments, including the use of metal-resistant bacteria; treatment additives such as calcium carbonate, phosphate, cement, manganese oxide, and magnesium hydroxide; the addition of clay minerals; and the use of chelating agents. JF - Environmental Health Perspectives AU - Sandrin, Todd R AU - Maier, Raina M Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1093 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - TOXIC SUBSTANCES KW - SOIL CONTAMINATION KW - ORGANIC COMPOUNDS KW - BIODEGRADATION, MICROORGANISM KW - CHEMICAL CONTAMINATION, MULTIPLE KW - HEAVY METALS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14663007?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Impact+of+Metals+on+the+Biodegradation+of+Organic+Pollutants&rft.au=Sandrin%2C+Todd+R%3BMaier%2C+Raina+M&rft.aulast=Sandrin&rft.aufirst=Todd&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1093&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL CONTAMINATION, MULTIPLE; TOXIC SUBSTANCES; ORGANIC COMPOUNDS; SOIL CONTAMINATION; HEAVY METALS; BIODEGRADATION, MICROORGANISM ER - TY - JOUR T1 - Airborne Particles of the California Central Valley Alter the Lungs of Healthy Adult Rats AN - 14662496; 10645639 AB - Healthy male SpragueDawley rats were exposed to either room air passed through an activated carbon-impregnated filter media pad or to fine and ultrafine concentrated ambient particles collected in Fresno, CA, and bronchoalveolar lavage cell viability and total cells, as well as the number and relative proportion of macrophages, neutrophils, and lymphocytes, were measured after 3 d of exposure. The experiments were conducted during three consecutive weeks in the fall of 2000 and three consecutive weeks in the winter of 2001. A unique particle concentrator was used, which was able to concentrate particles in both fine and ultrafine sizes to identify specific biologic responses. Consistent cytotoxic and inflammatory responses associated with the exposure were found. The two highest mass concentrations were associated with a significant increase in numbers of total cells and/or neutrophils recovered from the lungs by bronchoalveolar lavage. Lung cytotoxicity measured in the bronchoalveolar lavage fluid of animals exposed to concentrated ambient particles was also increased significantly, but the measure of cytotoxicity was not dependent upon particle mass. JF - Environmental Health Perspectives AU - Smith, Kevin R AU - Kim, Seongheon AU - Recendez, Julian J AU - Teague, Stephen V AU - Menache, Margaret G AU - Grubbs, David E AU - Sioutas, Constantinos Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 902 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CYTOTOXICITY KW - PARTICULATE SIZE KW - PARTICULATES KW - CALIFORNIA KW - PULMONARY EFFECTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14662496?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Airborne+Particles+of+the+California+Central+Valley+Alter+the+Lungs+of+Healthy+Adult+Rats&rft.au=Smith%2C+Kevin+R%3BKim%2C+Seongheon%3BRecendez%2C+Julian+J%3BTeague%2C+Stephen+V%3BMenache%2C+Margaret+G%3BGrubbs%2C+David+E%3BSioutas%2C+Constantinos&rft.aulast=Smith&rft.aufirst=Kevin&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=902&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CALIFORNIA; AIR POLLUTION EFFECTS; CYTOTOXICITY; PARTICULATE SIZE; PULMONARY EFFECTS; PARTICULATES ER - TY - JOUR T1 - Clinical and Laboratory Investigation of Allergy to Genetically Modified Foods AN - 14662490; 10645894 AB - Various clinical aspects of food allergy relevant to the assessment of novel proteins in genetically modified foods are reviewed. Most of the focus for clinical evaluation of genetically modified foods has been in IgE-mediated anaphylaxis, and decision trees have been developed for identifying whether novel proteins cause such anaphylactic reactions. The clinical spectra of food allergy, including both IgE- and non-IgE-mediated allergic reactions, are outlined, and allergenicity risk assessment is considered, noting the clinical and laboratory methods used in assessing the allergenicity of foods. Experiences with StarLink corn and in occupational cohorts exposed to grain dusts suggest that the development of methods to be used for postmarket consumer and occupational health surveillance may be useful. JF - Environmental Health Perspectives AU - Bernstein, Jonathan A AU - Bernstein, ILeonard AU - Bucchini, Luca AU - Goldman, Lynn R AU - Hamilton, Robert G AU - Lehrer, Samuel AU - Rubin, Carol Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1114 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOTECHNOLOGY KW - PROTEIN KW - RISK ASSESSMENT KW - GENETIC ENGINEERING KW - ALLERGIES KW - FOOD ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14662490?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Clinical+and+Laboratory+Investigation+of+Allergy+to+Genetically+Modified+Foods&rft.au=Bernstein%2C+Jonathan+A%3BBernstein%2C+ILeonard%3BBucchini%2C+Luca%3BGoldman%2C+Lynn+R%3BHamilton%2C+Robert+G%3BLehrer%2C+Samuel%3BRubin%2C+Carol&rft.aulast=Bernstein&rft.aufirst=Jonathan&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1114&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; BIOTECHNOLOGY; PROTEIN; GENETIC ENGINEERING; ALLERGIES; FOOD ANALYSIS ER - TY - JOUR T1 - Organochlorines, Lead, and Mercury in Akwesasne Mohawk Youth AN - 14662473; 10645647 AB - The Mohawk Territory of Akwesasne is adjacent to several industrial complexes in the St. Lawrence River valley, as well as to several Superfund sites. Industrial development and production over time in the valley have led to contamination of the St. Lawrence and its river tributaries with PCBs and other persistent organic pollutants. The Mohawk have relied heavily on locally caught fish and game as sources of protein. Results are presented from a study in which the levels of several toxicants were measured in a sample of youth from the Akwesasne Mohawk community. Demographic and lifestyle data were obtained via questionnaire, and blood samples were collected and analyzed for organochlorines, lead, and mercury. The patterns and levels of serum PCB congeners in Mohawk youth were found to be consistent with a combination of cumulative and recent PCB exposure, and the relatively high detection rates of the shorter-lived congeners suggested a continuing source of exposure. Elevated serum levels of the persistent congeners were typical of cumulative, nonoccupational exposure scenarios. The levels of Hg and Pb were low. JF - Environmental Health Perspectives AU - Schell, Lawrence M AU - Hubicki, Lech A AU - DeCaprio, Anthony P AU - Gallo, Mia V AU - Ravenscroft, Julia AU - Tarbell, Alice AU - Jacobs, Agnes Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 954 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ST LAWRENCE RIVER BASIN KW - POLYCHLORINATED BIPHENYLS KW - ORGANOCHLORINE PESTICIDES KW - BIOACCUMULATION, HUMAN KW - BLOOD ANALYSIS KW - LEAD KW - AMERICAN INDIANS KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14662473?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Organochlorines%2C+Lead%2C+and+Mercury+in+Akwesasne+Mohawk+Youth&rft.au=Schell%2C+Lawrence+M%3BHubicki%2C+Lech+A%3BDeCaprio%2C+Anthony+P%3BGallo%2C+Mia+V%3BRavenscroft%2C+Julia%3BTarbell%2C+Alice%3BJacobs%2C+Agnes&rft.aulast=Schell&rft.aufirst=Lawrence&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=954&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ST LAWRENCE RIVER BASIN; POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; LEAD; AMERICAN INDIANS; BIOACCUMULATION, HUMAN; MERCURY; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Parkinson's Disease and Exposure to Infectious Agents and Pesticides and the Occurrence of Brain Injuries: Role of Neuroinflammation AN - 14662416; 10645889 AB - The development of parkinsonian syndrome has been attributed to mutations in several recently identified genes, whereas the development of idiopathic Parkinson's disease may represent the final outcome of a complex set of interactions among the innate vulnerabilities of the nigrostriatal dopaminergic system, potential genetic predisposition, and exposure to environmental toxicants. Evidence has suggested the role of inflammation in the brain in the pathogenesis of the diseases, which can be induced by exposure to either infectious agents or toxicants. The literature on the potential impact on the development of idiopathic Parkinson's disease of environmental factors, such as exposure to infectious agents and pesticides and early-life occurrence of brain injuries, is reviewed, and a possible link is established between early-life neuroinflammation and later-life development of idiopathic Parkinson's disease, focusing on the role of glial cells in pesticide-induced dopaminergic neurodegeneration. JF - Environmental Health Perspectives AU - Liu, Bin AU - Gao, Hui-Ming AU - Hong, Jau-Shyong Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1065 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PARKINSONS DISEASE KW - NEUROTOXICITY KW - PATHOLOGY, HUMAN KW - PESTICIDE EXPOSURE KW - VIRUSES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14662416?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Parkinson%27s+Disease+and+Exposure+to+Infectious+Agents+and+Pesticides+and+the+Occurrence+of+Brain+Injuries%3A+Role+of+Neuroinflammation&rft.au=Liu%2C+Bin%3BGao%2C+Hui-Ming%3BHong%2C+Jau-Shyong&rft.aulast=Liu&rft.aufirst=Bin&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1065&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PARKINSONS DISEASE; NEUROTOXICITY; PATHOLOGY, HUMAN; PESTICIDE EXPOSURE; VIRUSES ER - TY - JOUR T1 - The Role of Genetic Polymorphisms in Environmental Health AN - 14662118; 10645888 JF - Environmental Health Perspectives AU - Kelada, Samir N AU - Eaton, David L AU - Wang, Sophia S AU - Rothman, Nathaniel R AU - Khoury, Muin J Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1055 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - DISEASES AND DISORDERS KW - SUSCEPTIBILITY KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14662118?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Role+of+Genetic+Polymorphisms+in+Environmental+Health&rft.au=Kelada%2C+Samir+N%3BEaton%2C+David+L%3BWang%2C+Sophia+S%3BRothman%2C+Nathaniel+R%3BKhoury%2C+Muin+J&rft.aulast=Kelada&rft.aufirst=Samir&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1055&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; DISEASES AND DISORDERS; SUSCEPTIBILITY; GENETICS, HUMAN ER - TY - JOUR T1 - Childhood Leukemia: Electric and Magnetic Fields as Possible Risk Factors AN - 14661199; 10645648 JF - Environmental Health Perspectives AU - Brain, Joseph D AU - Kavet, Robert AU - McCormick, David L AU - Poole, Charles AU - Silverman, Lewis B AU - Smith, Thomas J AU - Valberg, Peter A Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 962 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PATHOLOGY, CHILDREN KW - DISEASES AND DISORDERS KW - HUMAN T CELL LEUKEMIA VIRUS KW - ELECTROMAGNETIC FIELDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14661199?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Childhood+Leukemia%3A+Electric+and+Magnetic+Fields+as+Possible+Risk+Factors&rft.au=Brain%2C+Joseph+D%3BKavet%2C+Robert%3BMcCormick%2C+David+L%3BPoole%2C+Charles%3BSilverman%2C+Lewis+B%3BSmith%2C+Thomas+J%3BValberg%2C+Peter+A&rft.aulast=Brain&rft.aufirst=Joseph&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=962&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; PATHOLOGY, CHILDREN; HUMAN T CELL LEUKEMIA VIRUS; ELECTROMAGNETIC FIELDS ER - TY - JOUR T1 - Maternal Serum Dioxin Levels and Birth Outcomes in Women of Seveso, Italy AN - 14661168; 10645646 AB - Significant human exposure to TCDD occurred in Seveso, Italy, in 1976 as the result of a trichlorophenol plant explosion. The Seveso Women's Health Study was initiated 20 yr after the explosion to determine whether there was an association between TCDD exposure and reproductive health. Serum samples collected soon after the explosion were used to examine the relationship between maternal serum TCDD levels and risk of adverse pregnancy outcome in post-explosion pregnancies. The median maternal serum TCDD level at the time of the explosion was 46.6 ppt, with highest levels found in the youngest group of women, women who were nulliparous at the time of the explosion, and women with the shortest time of recall to their pregnancy. No profound effects of TCDD exposure on pregnancy outcomes were observed, but the associations with serum TCDD levels were somewhat stronger, albeit nonsignificant, for lowered birth weight and the occurrence of small for gestational age infants in pregnancies that ended within the first half-live of TCDD after the explosion. JF - Environmental Health Perspectives AU - Eskenazi, Brenda AU - Mocarelli, Paolo AU - Warner, Marcella AU - Chee, Wan-Ying AU - Gerthoux, Pier Mario AU - Samuels, Steven AU - Needham, Larry L Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 947 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - PREGNANCY KW - ITALY KW - TETRACHLORODIBENZODIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14661168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Maternal+Serum+Dioxin+Levels+and+Birth+Outcomes+in+Women+of+Seveso%2C+Italy&rft.au=Eskenazi%2C+Brenda%3BMocarelli%2C+Paolo%3BWarner%2C+Marcella%3BChee%2C+Wan-Ying%3BGerthoux%2C+Pier+Mario%3BSamuels%2C+Steven%3BNeedham%2C+Larry+L&rft.aulast=Eskenazi&rft.aufirst=Brenda&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=947&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; REPRODUCTION, HUMAN; PREGNANCY; ITALY; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Cytopathology of the Nasal Mucosa in Chronic Exposure to Diesel Engine Emission: a Five-Year Survey of Swiss Customs Officers AN - 14660584; 10645642 AB - In Switzerland, brush cytology nasal probes were taken from 194 male, nonsmoking customs officers twice a year over a period of 5 yr to assess chronic exposure to diesel engine emissions. The nasal mucosa responses were compared with those of their colleagues working only in the office. The epithelia and leukocytes deviated from the norm in the diesel engine emission-exposed subjects. Distinct deviations from the cytologic cell count obtained in the nonexposed subjects were also observed in the exposed officers, with goblet cells increased significantly in the exposed subjects, and the exposed officers exhibited a distinct increase in metaplastic squamous cells. Dysplastic squamous and columnar cells were found exclusively in the exposed subjects. JF - Environmental Health Perspectives AU - Gluck, Ulrich AU - Schutz, Rudolf AU - Gebbers, Jan-Olaf Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 925 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CYTOTOXICITY KW - PATHOLOGY, HUMAN KW - HEALTH SAFETY, OCCUPATIONAL KW - SWITZERLAND KW - DIESEL ENGINES, TRANSPORT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14660584?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cytopathology+of+the+Nasal+Mucosa+in+Chronic+Exposure+to+Diesel+Engine+Emission%3A+a+Five-Year+Survey+of+Swiss+Customs+Officers&rft.au=Gluck%2C+Ulrich%3BSchutz%2C+Rudolf%3BGebbers%2C+Jan-Olaf&rft.aulast=Gluck&rft.aufirst=Ulrich&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=925&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; AIR POLLUTION EFFECTS; CYTOTOXICITY; PATHOLOGY, HUMAN; SWITZERLAND; DIESEL ENGINES, TRANSPORT ER - TY - JOUR T1 - Insecticidal Juvenile Hormone Analogs Stimulate the Production of Male Offspring in the Crustacean Daphnia magna AN - 14660551; 10645641 AB - Daphnia magna were exposed to a variety of chemicals to determine if the stimulation of male production was unique to juvenile hormone analogs (JHAs), which represent a class of insecticides designed specifically to disrupt endocrine-regulated processes. In addition, the ability of the JHAs, methoprene and pyriproxyfen, to program sex in oocytes during ovarian maturation was studied, and binary combinations of the JHAs and methyl farnesoate were evaluated for concentration additivity. Results showed that only methyl farnesoate and pyriproxyfen altered the sex ratios of offspring in favor of males, with pyriproxyfen two to three orders of magnitude more potent. Exposure of oocytes to methyl farnesoate during ovarian development programmed the oocytes to develop into male offspring in a concentration-dependent manner. The same effect was observed for pyriproxyfen and methoprene, but the latter required much higher exposure concentrations. Binary combinations of either JHA with methyl farnesoate stimulated male progeny production in a manner that better correlated to the model for concentration additivity than to that for independent joint action. JF - Environmental Health Perspectives AU - Olmstead, Allen W AU - LeBlanc, Gerald A Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 919 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - HORMONAL EFFECTS KW - CHEMICAL CONTAMINATION, MULTIPLE KW - INSECTICIDE EXPOSURE KW - DOSE RESPONSE PROFILES KW - CRUSTACEANS KW - REPRODUCTION, INSECT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14660551?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Insecticidal+Juvenile+Hormone+Analogs+Stimulate+the+Production+of+Male+Offspring+in+the+Crustacean+Daphnia+magna&rft.au=Olmstead%2C+Allen+W%3BLeBlanc%2C+Gerald+A&rft.aulast=Olmstead&rft.aufirst=Allen&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=919&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; CHEMICAL CONTAMINATION, MULTIPLE; DOSE RESPONSE PROFILES; INSECTICIDE EXPOSURE; CRUSTACEANS; REPRODUCTION, INSECT; HORMONAL EFFECTS ER - TY - JOUR T1 - Disparities in Exposure to Air Pollution During Pregnancy AN - 14660538; 10645645 AB - An air pollution index representing long-term exposure to five critical pollutants was created for 199899 using a database of ambient air quality measurements made by federal, state, and local air pollution control agencies, and the index was used to examine whether mothers with lower socioeconomic status, as measured by lower educational attainment, and mothers in various race/ethnic groups were more likely to live in areas with higher aggregate levels of air pollution. Air pollution exposure was examined in relation to birth outcomes, including preterm delivery and small size for gestational age. The unadjusted mean level of the air pollution index was lower for white mothers and American Indian/Alaska Native mothers than for Hispanic, African-American, and Asian/Pacific Islander mothers. Race was associated significantly with the mean air index for Hispanic and African-American mothers compared with white mothers after adjusting for educational attainment, age, parity, marital status, and region of the country. Mothers with lower educational attainment lived in areas with a higher mean level of the air pollution index than did mothers with higher educational attainment, and Hispanic mothers were the most likely to live in areas with the highest decile of the air index compared with white mothers. Increasing levels of air pollution were associated with preterm delivery, but not with small size for gestational age. JF - Environmental Health Perspectives AU - Woodruff, Tracey J AU - Parker, Jennifer D AU - Kyle, Amy D AU - Schoendorf, Kenneth C Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 942 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - AIR POLLUTION INDEX KW - PREGNANCY KW - SPATIAL COMPARISONS KW - ENV JUSTICE KW - SOCIOECONOMICS KW - REPRODUCTION, HUMAN KW - RACIAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14660538?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Disparities+in+Exposure+to+Air+Pollution+During+Pregnancy&rft.au=Woodruff%2C+Tracey+J%3BParker%2C+Jennifer+D%3BKyle%2C+Amy+D%3BSchoendorf%2C+Kenneth+C&rft.aulast=Woodruff&rft.aufirst=Tracey&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=942&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; AIR POLLUTION EFFECTS; SOCIOECONOMICS; AIR POLLUTION INDEX; REPRODUCTION, HUMAN; PREGNANCY; RACIAL COMPARISONS; SPATIAL COMPARISONS ER - TY - JOUR T1 - Key Issues for the Assessment of the Allergenic Potential of Genetically Modified Foods: Breakout Group Reports AN - 14660177; 10645897 AB - As part of the Assessment of the Allergic Potential of Genetically Modified Foods" workshop convened in December 2001, speakers and participants met in breakout groups to discuss key issues in a number of different areas. A brief summary is provided of the discussions in each of the groups regarding the current state of knowledge and what information is needed to advance the field. The areas considered are: use of human clinical data, animal models to assess food allergy, biomarkers of exposure and effect, sensitive populations, doseresponse assessment, and postmarket surveillance. In each area, the adequacy of the current tools available for assessment of the allergenic potential of novel foods and how the tools need to be improved are examined. JF - Environmental Health Perspectives AU - Germolec, Dori R AU - Kimber, Ian AU - Goldman, Lynn AU - Selgrade, MaryJane Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1131 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOTECHNOLOGY KW - IMMUNE RESPONSE KW - RISK ASSESSMENT KW - GENETIC ENGINEERING KW - ALLERGIES KW - FOOD ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14660177?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Key+Issues+for+the+Assessment+of+the+Allergenic+Potential+of+Genetically+Modified+Foods%3A+Breakout+Group+Reports&rft.au=Germolec%2C+Dori+R%3BKimber%2C+Ian%3BGoldman%2C+Lynn%3BSelgrade%2C+MaryJane&rft.aulast=Germolec&rft.aufirst=Dori&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1131&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; BIOTECHNOLOGY; GENETIC ENGINEERING; ALLERGIES; FOOD ANALYSIS; IMMUNE RESPONSE ER - TY - JOUR T1 - Environmental Pollutants and Breast Cancer AN - 14660098; 10645885 AB - Epidemiologic studies of hormonal factors in human breast cancer and animal studies of the hormonal activity and carcinogenic potential of specific synthetic chemicals have suggested environmental pollutants as possible sources of risk. Here, promising leads in the study of environmental pollutants and breast cancer are identified. Data are presented on trends in the incidence of breast cancer and mortality, and animal studies are reviewed of chemicals that may be breast carcinogens, promote the growth of breast cells and hormonally sensitive tumors, or affect mammary gland development and susceptibility. Recommendations are proposed for further research in the areas of exposure assessment, toxicology and mammary gland biology, and individual susceptibility and intermediate outcomes. JF - Environmental Health Perspectives AU - Brody, Julia Green AU - Rudel, Ruthann A Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 1007 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - SOLVENTS KW - HORMONAL EFFECTS KW - CHEMICAL CONTAMINATION KW - POLYCYCLIC AROMATIC HYDROCARBON KW - CARCINOGENIC AGENTS KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14660098?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Environmental+Pollutants+and+Breast+Cancer&rft.au=Brody%2C+Julia+Green%3BRudel%2C+Ruthann+A&rft.aulast=Brody&rft.aufirst=Julia&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1007&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOLVENTS; CANCER RISK; CARCINOGENIC AGENTS; HORMONAL EFFECTS; CHEMICAL CONTAMINATION; PESTICIDE EXPOSURE; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Chemical Analysis of World Trade Center Fine Particulate Matter for Use in Toxicologic Assessment AN - 14658158; 10645649 AB - With the attack on the World Trade Center in New York City on September 11, 2001, significant quantities of pollutants were released into the surrounding neighborhoods, including particulates, asbestos, metals, and organic compounds. On the following 2 d, settled dust samples were collected at several sites within the immediate vicinity of Ground Zero, which were separated into fine, coarse, and larger fractions and analyzed for their chemical constituents. Results are summarized from the extensive characterization, including those from the application of scanning electron microscopy, X-ray diffraction, X-ray fluorescence, carbon fraction analysis, neutron activation analysis, inductively coupled plasmamass spectrometry, and inductively coupled plasmaatomic emission spectrometry. The particulate matter was found to be composed primarily of calcium-based compounds, while the content of transition and heavy metals and other toxic elements was low compared with that of combustion-derived residual oil flyash. The likely major acute inhalation hazards of the particulates would be due to the presence of gypsum, calcite, and cement or concrete dust components. JF - Environmental Health Perspectives AU - McGee, John K AU - Chen, Lung Chi AU - Cohen, Mitchell D AU - Chee, Glen R AU - Prophete, Colette M AU - Haykal-Coates, Najwa AU - Wasson, Shirley J Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 972 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RESPIRABLE DUST KW - PARTICULATES KW - RISK ASSESSMENT KW - HEAVY METALS KW - CALCIUM COMPOUNDS KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14658158?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Chemical+Analysis+of+World+Trade+Center+Fine+Particulate+Matter+for+Use+in+Toxicologic+Assessment&rft.au=McGee%2C+John+K%3BChen%2C+Lung+Chi%3BCohen%2C+Mitchell+D%3BChee%2C+Glen+R%3BProphete%2C+Colette+M%3BHaykal-Coates%2C+Najwa%3BWasson%2C+Shirley+J&rft.aulast=McGee&rft.aufirst=John&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=972&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; HEAVY METALS; RESPIRABLE DUST; CALCIUM COMPOUNDS; PARTICULATES; NEW YORK CITY ER - TY - JOUR T1 - Increased Concentrations of Polychlorinated Biphenyls, Hexachlorobenzene, and Chlordanes in Mothers of Men with Testicular Cancer AN - 14658140; 10645643 AB - Concentrations of specific persistent organic pollutants were measured in blood obtained from men with testicular cancer and in blood of their mothers, and the levels were compared with matched controls. The study was conducted in Sweden. In cases with testicular cancer, the only significant difference in pollutant concentrations in blood was an increased concentration of cis-nonachlordane. In mothers, however, significantly increased concentrations of PCBs, hexachlorobenzene, trans- and cis-nonachlordane, and sum of chlordanes were found in the case mothers compared to controls. JF - Environmental Health Perspectives AU - Hardell, Lennart AU - van Bavel, Bert AU - Lindstrom, Gunilla AU - Carlberg, Michael AU - Dreifaldt, Ann Charlotte AU - Wijkstrom, Hans AU - Starkhammar, Hans Y1 - 2003/06// PY - 2003 DA - Jun 2003 SP - 930 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 111 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - HEXACHLOROBENZENE KW - CHLORDANE KW - BLOOD ANALYSIS KW - CARCINOGENIC AGENTS KW - DISEASES AND DISORDERS KW - REPRODUCTION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14658140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Increased+Concentrations+of+Polychlorinated+Biphenyls%2C+Hexachlorobenzene%2C+and+Chlordanes+in+Mothers+of+Men+with+Testicular+Cancer&rft.au=Hardell%2C+Lennart%3Bvan+Bavel%2C+Bert%3BLindstrom%2C+Gunilla%3BCarlberg%2C+Michael%3BDreifaldt%2C+Ann+Charlotte%3BWijkstrom%2C+Hans%3BStarkhammar%2C+Hans&rft.aulast=Hardell&rft.aufirst=Lennart&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=930&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; DISEASES AND DISORDERS; CARCINOGENIC AGENTS; REPRODUCTION, HUMAN; HEXACHLOROBENZENE; CHLORDANE ER -