TY - GEN T1 - Intelligence Reform and Terrorism Prevention Act of 2004: "Lone Wolf" Amendment to the Foreign Intelligence Surveillance Act AN - 1679112690; SU00201 AB - Describes new "lone wolf" provision of Foreign Intelligence Surveillance Act when applied to "agent of a foreign power" and its impact on procedures for seeking FISA warrants. AU - United States. Library of Congress. Congressional Research Service. American Law Division AD - United States. Library of Congress. Congressional Research Service. American Law Division PY - 2004 SP - 6 KW - Americans KW - Executive Order 12333 (1981) KW - Foreign Intelligence Surveillance Act (1978) KW - Intelligence Reform and Terrorism Prevention Act (2004) KW - Noncitizens KW - Pen registers KW - Searches and seizures KW - Terrorism KW - United States Constitution. First Amendment KW - Warrants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679112690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_su&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Intelligence+Reform+and+Terrorism+Prevention+Act+of+2004%3A+%22Lone+Wolf%22+Amendment+to+the+Foreign+Intelligence+Surveillance+Act&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service.+American+Law+Division&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service.+American+Law+Division&rft.aufirst=&rft.date=2004-12-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ L2 - http://www.fas.org. LA - English DB - Digital National Security Archive N1 - Name - United States. Federal Bureau of Investigation; United States. Foreign Intelligence Surveillance Court N1 - Publication note - National Security Archive. Wiretap Debate Déjà Vu. Electronic Briefing Book 178, February 4, 2006, http://www2.gwu.edu/~nsarchiv/NSAEBB/NSAEBB178/ (previously published document) N1 - Analyte descriptor - NSA document type: Report ; Location of original: Available [Online]: Federation of American Scientists N1 - Last updated - 2015-12-14 ER - TY - JOUR T1 - Splicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay. AN - 67204005; 15608055 AB - Metazoan cells have two pathways for intron removal involving the U2- and U12-type spliceosomes, which contain mostly nonoverlapping sets of small nuclear ribonucleoproteins. We show that in vitro splicing of a U12-type intron assembles an exon junction complex (EJC) that is comparably positioned and contains many of the same components as that deposited by the U2-type spliceosome. The presence of a U12-type intron downstream of a premature termination codon within an open reading frame (ORF) induces nonsense-mediated decay of the mRNA in vivo. These findings suggest a common pathway for EJC assembly by the two spliceosomes and highlight the evolutionary age of the EJC and its downstream functions in gene expression. JF - Proceedings of the National Academy of Sciences of the United States of America AU - Hirose, Tetsuro AU - Shu, Mei-Di AU - Steitz, Joan A AD - Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. Y1 - 2004/12/28/ PY - 2004 DA - 2004 Dec 28 SP - 17976 EP - 17981 VL - 101 IS - 52 SN - 0027-8424, 0027-8424 KW - Codon, Nonsense KW - 0 KW - DNA, Complementary KW - RNA Precursors KW - RNA, Messenger KW - RNA, Small Nuclear KW - Ribonucleoproteins, Small Nuclear KW - U12 small nuclear RNA KW - RNA KW - 63231-63-0 KW - Ribonuclease H KW - EC 3.1.26.4 KW - Index Medicus KW - Ribonuclease H -- chemistry KW - RNA Precursors -- metabolism KW - Plasmids -- metabolism KW - Cell Nucleus -- metabolism KW - Exons KW - HeLa Cells KW - Humans KW - Open Reading Frames KW - Immunoprecipitation KW - Ribonucleoproteins, Small Nuclear -- metabolism KW - Evolution, Molecular KW - Mutagenesis, Site-Directed KW - Transfection KW - Spliceosomes -- metabolism KW - RNA -- metabolism KW - DNA, Complementary -- metabolism KW - RNA -- chemistry KW - Gene Expression Regulation KW - Time Factors KW - Cell Line KW - RNA, Messenger -- metabolism KW - RNA, Small Nuclear -- metabolism KW - RNA Splicing KW - Introns KW - RNA, Small Nuclear -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67204005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Splicing+of+U12-type+introns+deposits+an+exon+junction+complex+competent+to+induce+nonsense-mediated+mRNA+decay.&rft.au=Hirose%2C+Tetsuro%3BShu%2C+Mei-Di%3BSteitz%2C+Joan+A&rft.aulast=Hirose&rft.aufirst=Tetsuro&rft.date=2004-12-28&rft.volume=101&rft.issue=52&rft.spage=17976&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.issn=00278424&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-02-28 N1 - Date created - 2004-12-29 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: EMBO J. 2002 Jul 1;21(13):3536-45 [12093754] Nature. 2002 May 16;417(6886):304-8 [11979277] Curr Biol. 2002 Jul 9;12(13):1060-7 [12121612] Genes Dev. 2002 Nov 1;16(21):2778-91 [12414731] J Cell Biol. 2002 Nov 25;159(4):579-88 [12438415] Science. 2002 Dec 13;298(5601):2205-8 [12411573] Mol Cell. 2003 Mar;11(3):837-43 [12667464] EMBO J. 2003 May 15;22(10):2472-83 [12743041] Mol Cell. 2003 Jul;12(1):113-23 [12887897] Mol Cell Biol. 2003 Oct;23(20):7363-76 [14517304] Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11327-32 [12972633] Nat Rev Mol Cell Biol. 2003 Dec;4(12):960-70 [14685174] RNA. 2004 Feb;10(2):200-9 [14730019] Genes Dev. 2004 Jan 15;18(2):210-22 [14752011] J Biol Chem. 2004 Feb 20;279(8):7009-13 [14625303] Nature. 2004 Feb 19;427(6976):753-7 [14973490] Nat Rev Mol Cell Biol. 2004 Feb;5(2):89-99 [15040442] Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4118-23 [15024115] Nat Struct Mol Biol. 2004 Apr;11(4):346-51 [15034551] RNA. 2004 Jun;10(6):929-41 [15146077] Nucleic Acids Res. 1983 Mar 11;11(5):1475-89 [6828386] J Biol Chem. 1990 Nov 15;265(32):19624-31 [2246248] Cell. 1996 Mar 8;84(5):801-11 [8625417] Trends Biochem Sci. 1997 Apr;22(4):132-7 [9149533] Genes Dev. 1997 Jul 15;11(14):1864-72 [9242493] RNA. 1998 Jul;4(7):801-15 [9671053] Mol Cell. 1998 Dec;2(6):773-85 [9885565] Mol Cell Biol. 1999 Mar;19(3):1705-19 [10022858] Genes Dev. 1999 Apr 1;13(7):851-63 [10197985] Science. 1999 Jun 18;284(5422):2003-5 [10373121] RNA. 1999 Jul;5(7):893-908 [10411133] Genes Dev. 2000 May 1;14(9):1098-108 [10809668] Nature. 2000 Sep 21;407(6802):401-5 [11014198] EMBO J. 2000 Dec 15;19(24):6860-9 [11118221] Cell. 2000 Dec 22;103(7):1121-31 [11163187] Mol Cell. 2001 Jan;7(1):217-26 [11172726] EMBO J. 2001 Aug 15;20(16):4536-46 [11500380] EMBO J. 2001 Sep 3;20(17):4987-97 [11532962] Nat Cell Biol. 2001 Sep;3(9):E201-4 [11533670] Science. 2001 Sep 7;293(5536):1832-6 [11546873] Science. 2001 Sep 7;293(5536):1836-9 [11546874] Nature. 2001 Oct 11;413(6856):644-7 [11675789] EMBO J. 2001 Nov 15;20(22):6424-33 [11707413] Mol Cell Biol. 2002 May;22(10):3219-29 [11971955] EMBO J. 2002 Jul 15;21(14):3804-15 [12110592] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Be The First CIO Of The U.S. Senate AN - 205940862 JF - CIO AU - J. Greg Hanson Assistant sergeant at arms and CIO for the U.S. Senate. Y1 - 2004/12/15/ PY - 2004 DA - 2004 Dec 15 SP - 1 CY - Framingham PB - CXO Media, Inc. VL - 18 IS - 6 SN - 08949301 KW - Business And Economics--Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/205940862?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabiglobal&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=CIO&rft.atitle=Be+The+First+CIO+Of+The+U.S.+Senate&rft.au=J.+Greg+Hanson+Assistant+sergeant+at+arms+and+CIO+for+the+U.S.+Senate.&rft.aulast=J.+Greg+Hanson+Assistant+sergeant+at+arms+and+CIO+for+the+U.S.+Senate.&rft.aufirst=&rft.date=2004-12-15&rft.volume=18&rft.issue=6&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=CIO&rft.issn=08949301&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright 2004 CXO Media Inc N1 - Last updated - 2014-05-22 ER - TY - JOUR T1 - Water Infrastructure Project Earmarks in EPA Appropriations: Trends and Policy Implications AN - 14737552; 10675644 AB - Earmarks in appropriations legislation are funds set aside within an account for specified projects or locations. These have been increasing in recent years as a way to help designated communities meet needs to build and upgrade water infrastructure systems, whose estimated future funding needs exceed $300 billion. Of the $40.8 billion appropriated to EPA for water infrastructure assistance under the Clean Water Act and the Safe Drinking Water Act since 1989, 16% has gone to earmarked project grants. The trend of appropriators to earmark smaller awards is reflected in the fact that only 62 of 520 in FY2004 and 76 in FY2005 received amounts of $1 million or more. JF - US Congressional Research Service Report RL32201 AU - Copeland, Claudia Y1 - 2004/12/15/ PY - 2004 DA - 2004 Dec 15 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - EPA, FEDERAL KW - CLEAN WATER ACT KW - WATER RESOURCES DEVELOPMENT KW - URBAN WATER RESOURCES KW - WATER RESOURCES FINANCING KW - SAFE DRINKING WATER ACT 74 KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14737552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+RL32201&rft.atitle=Water+Infrastructure+Project+Earmarks+in+EPA+Appropriations%3A+Trends+and+Policy+Implications&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-12-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+RL32201&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - URBAN WATER RESOURCES; WATER RESOURCES FINANCING; EPA, FEDERAL; SAFE DRINKING WATER ACT 74; CLEAN WATER ACT; WATER RESOURCES DEVELOPMENT ER - TY - JOUR T1 - Safe Drinking Water Act: Implementation and Issues AN - 14737122; 10675645 AB - Key drinking water issues in the 108th Congress involved water infrastructure funding and problems posed by methyl tert butyl ether (MTBE), lead, and other specific water pollutants. Both chambers passed bills to address MTBE contamination, and Congress required health studies of perchlorate and directed DOD and EPA to research perchlorate groundwater pollution in the southwest. For FY2005, Congress approved about $850 million for the drinking water state revolving fund program. Bills were also submitted to increase funding for water infrastructure projects, with emphasis on assisting small systems. JF - US Congressional Research Service Report IB10118 AU - Tiemann, Mary Y1 - 2004/12/08/ PY - 2004 DA - 2004 Dec 08 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - FUEL ADDITIVES KW - GROUNDWATER KW - STATE AND LOCAL ENV PROGRAMS KW - WATER RESOURCES FINANCING KW - SAFE DRINKING WATER ACT 74 KW - WATER QUALITY STANDARDS KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14737122?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10118&rft.atitle=Safe+Drinking+Water+Act%3A+Implementation+and+Issues&rft.au=Tiemann%2C+Mary&rft.aulast=Tiemann&rft.aufirst=Mary&rft.date=2004-12-08&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10118&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - STATE AND LOCAL ENV PROGRAMS; WATER RESOURCES FINANCING; SAFE DRINKING WATER ACT 74; LEAD; WATER QUALITY STANDARDS; GROUNDWATER; FUEL ADDITIVES ER - TY - JOUR T1 - Clean Water Act Issues in the 108th Congress AN - 14737324; 10675642 AB - Reauthorization of the wastewater infrastructure funding program of the Clean Water Act was considered by the 108th Congress. In October 2004, the Senate Environment and Public Works Committee reported legislation to authorize $20 billion in funding for clean water infrastructure. Other issues have received limited congressional attention, including whether and how the administration will revise the current program for restoration of pollution-impaired waters. Regulatory protection of wetlands, stormwater rules for the oil and gas industry, and animal waste management issues are also discussed. JF - US Congressional Research Service Report IB10108 AU - Copeland, Claudia Y1 - 2004/12/06/ PY - 2004 DA - 2004 Dec 06 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - LEGISLATION, FEDERAL KW - LIVESTOCK FEEDLOT RUNOFF KW - CLEAN WATER ACT KW - STORM RUNOFF KW - WATER POLLUTION CONTROL FINANCING KW - ENV RESTORATION KW - WATER QUALITY STANDARDS KW - WETLANDS KW - WATER QUALITY PROGRAMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14737324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10108&rft.atitle=Clean+Water+Act+Issues+in+the+108th+Congress&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-12-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10108&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - WATER POLLUTION CONTROL FINANCING; ENV RESTORATION; LEGISLATION, FEDERAL; LIVESTOCK FEEDLOT RUNOFF; CLEAN WATER ACT; STORM RUNOFF; WATER QUALITY STANDARDS; WETLANDS; WATER QUALITY PROGRAMS ER - TY - JOUR T1 - Carbon dioxide concentrations in the atmosphere of underground environments as tracers of climatic changes AN - 51230090; 2008-077543 JF - Eos, Transactions, American Geophysical Union AU - Madonia, P AU - Di Pietro, R AU - Francofonte, V AU - Anonymous Y1 - 2004/12// PY - 2004 DA - December 2004 SP - Abstract B33A EP - 0238 PB - American Geophysical Union, Washington, DC VL - 85 IS - 47, Suppl. SN - 0096-3941, 0096-3941 KW - concentration KW - terrestrial environment KW - monitoring KW - caves KW - Carburangeli Cave KW - atmosphere KW - Europe KW - Palermo Italy KW - Italy KW - climate change KW - cave environment KW - Southern Europe KW - carbon dioxide KW - Sicily Italy KW - Santa Ninfa Cave KW - tracers KW - ecology KW - depositional environment KW - solution features KW - 23:Geomorphology KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51230090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Eos%2C+Transactions%2C+American+Geophysical+Union&rft.atitle=Carbon+dioxide+concentrations+in+the+atmosphere+of+underground+environments+as+tracers+of+climatic+changes&rft.au=Madonia%2C+P%3BDi+Pietro%2C+R%3BFrancofonte%2C+V%3BAnonymous&rft.aulast=Madonia&rft.aufirst=P&rft.date=2004-12-01&rft.volume=85&rft.issue=47%2C+Suppl.&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Eos%2C+Transactions%2C+American+Geophysical+Union&rft.issn=00963941&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - American Geophysical Union 2004 fall meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - DC N1 - Last updated - 2012-06-07 N1 - CODEN - EOSTAJ N1 - SubjectsTermNotLitGenreText - atmosphere; carbon dioxide; Carburangeli Cave; cave environment; caves; climate change; concentration; depositional environment; ecology; Europe; Italy; monitoring; Palermo Italy; Santa Ninfa Cave; Sicily Italy; solution features; Southern Europe; terrestrial environment; tracers ER - TY - JOUR T1 - Correspondence: conflicts of interests: declarations for all. AN - 21425078; 12421263 AB - Concerning your editorial, "Embracing Scrutiny," in the October issue of EHP [Environ Health Perspect 112:A788 (2004)], the need for full disclosure of all potential conflicts of interest by all coauthors contributing to a publication in EHP is commendable and obviously needed. Might I take this one step further and suggest that all reviewers of EHP manuscripts be required to sign a form listing all of their potential conflicts of interest. JF - Environmental Health Perspectives AU - DW, Nebert Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A980 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - conflict of interests KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21425078?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+conflicts+of+interests%3A+declarations+for+all.&rft.au=DW%2C+Nebert&rft.aulast=DW&rft.aufirst=Nebert&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A980&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - conflict of interests ER - TY - JOUR T1 - The Relationship of Urinary Metabolites of Carbaryl/Naphthalene and Chlorpyrifos with Human Semen Quality AN - 21425004; 12425448 AB - Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure and decreased semen quality. In the present study we explored whether environmental exposures to 1-naphthol (1N), a metabolite of carbaryl and naphthalene, and 3,5,6-trichloro-2-pyridinol (TCPY), a metabolite of chlorpyrifos and chlorpyrifos-methyl, are associated with decreased semen quality in humans. Subjects (n=272) were recruited through a Massachusetts infertility clinic. Individual exposures were measured as spot urinary concentrations of 1N and TCPY adjusted using specific gravity. Semen quality was assessed as sperm concentration, percent motile sperm, and percent sperm with normal morphology, along with sperm motion parameters (straight-line velocity, curvilinear velocity, and linearity). Median TCPY and 1N concentrations were 3.22 and 3.19microg/L, respectively. For increasing 1N tertiles, adjusted odds ratios (ORs) were significantly elevated for below-reference sperm concentration (OR for low, medium, and high tertiles = 1.0, 4.2, 4.2, respectively; p-value for trend =0.01) and percent motile sperm (1.0, 2.5, 2.4; p-value for trend = 0.01). The sperm motion parameter most strongly associated with 1N was straight-line velocity. There were suggestive, borderline-significant associations for TCPY with sperm concentration and motility, whereas sperm morphology was weakly and nonsignificantly associated with both TCPY and 1N. The observed associations between altered semen quality and 1N are consistent with previous studies of carbaryl exposure, although suggestive associations with TCPY are difficult to interpret because human and animal data are currently limited. JF - Environmental Health Perspectives AU - Meeker, John D AU - Ryan, Louise AU - Barr, Dana B AU - Herrick, Robert F Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1665 EP - 1670 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Chlorpyrifos KW - USA, Massachusetts KW - Insecticides KW - Urine KW - Pesticides KW - Morphology KW - Carbaryl KW - Velocity KW - Naphthalene KW - Metabolites KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21425004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+of+Urinary+Metabolites+of+Carbaryl%2FNaphthalene+and+Chlorpyrifos+with+Human+Semen+Quality&rft.au=Meeker%2C+John+D%3BRyan%2C+Louise%3BBarr%2C+Dana+B%3BHerrick%2C+Robert+F&rft.aulast=Meeker&rft.aufirst=John&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1665&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Chlorpyrifos; Insecticides; Urine; Morphology; Pesticides; Naphthalene; Velocity; Carbaryl; Metabolites; USA, Massachusetts ER - TY - JOUR T1 - Is Bone Mineral Composition Disrupted by Organochlorines in East Greenland Polar Bears (Ursus maritimus)? AN - 21424957; 12425444 AB - We analyzed bone mineral density (BMD) in skulls of polar bears (Ursus maritimus) (n = 139) from East Greenland sampled during 1892-2002. Our primary goal was to detect possible changes in bone mineral content (osteopenia) due to elevated exposure to organochlorine [polychlorinated biphenyls (PCBs), dichlorodiphenyl trichloroethane (DDT) and its metabolites, chlordanes (CHLs), dieldrin, hexacyclohexanes, hexachlorobenzene] and polybrominated diphenyl ether (PBDE) compounds. To ensure that the BMD value in skull represented the mineral status of the skeletal system in general, we compared BMD values in femur and three lumbar vertebrae with skull in a subsample. We detected highly significant correlations between BMD in skull and femur (r = 0.99; p 0.001; n = 13) and skull and vertebrae (r = 0.97; p 0.001; n = 8). BMD in skulls sampled in the supposed pre-organochlorine/PBDE period (1892-1932) was significantly higher than that in skulls sampled in the supposed pollution period (1966-2002) for subadult females, subadult males, and adult males (all, p 0.05) but not adult females (p = 0.94). We found a negative correlation between organochlorines and skull BMD for the sum of PCBs (SigmaPCB; p 0.04) and SigmaCHL (p 0.03) in subadults and for dieldrin (p 0.002) and SigmaDDT (p 0.02) in adult males; indications for SigmaPBDE in subadults were also found (p = 0.06). In conclusion, the strong correlative relationships suggest that disruption of the bone mineral composition in East Greenland polar bears may have been caused by organochlorine exposure. JF - Environmental Health Perspectives AU - Sonne, Christian AU - Dietz, Rune AU - Born, Erik W AU - Riget, Frank F Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1711 EP - 1716 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - PBDE KW - Organochlorine compounds KW - Bones KW - Chlorine compounds KW - Dieldrin KW - Greenland, Oestgroenland KW - Vertebrae KW - polybrominated diphenyl ethers KW - Insecticides KW - mineral composition KW - Skull KW - bears KW - DDT KW - Ursus maritimus KW - Mineral composition KW - bone mineral density KW - Minerals KW - PCB compounds KW - PCB KW - Q5 08502:Methods and instruments KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21424957?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Is+Bone+Mineral+Composition+Disrupted+by+Organochlorines+in+East+Greenland+Polar+Bears+%28Ursus+maritimus%29%3F&rft.au=Sonne%2C+Christian%3BDietz%2C+Rune%3BBorn%2C+Erik+W%3BRiget%2C+Frank+F&rft.aulast=Sonne&rft.aufirst=Christian&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1711&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - PBDE; Bones; Skull; Chlorine compounds; DDT; Dieldrin; Mineral composition; Vertebrae; PCB; polybrominated diphenyl ethers; mineral composition; Insecticides; Organochlorine compounds; bears; PCB compounds; Minerals; bone mineral density; Ursus maritimus; Greenland, Oestgroenland ER - TY - JOUR T1 - Epidemiologic Evaluation of Measurement Data in the Presence of Detection Limits AN - 21424273; 12425433 AB - Quantitative measurements of environmental factors greatly improve the quality of epidemiologic studies but can pose challenges because of the presence of upper or lower detection limits or interfering compounds, which do not allow for precise measured values. We consider the regression of an environmental measurement (dependent variable) on several covariates (independent variables). Various strategies are commonly employed to impute values for interval-measured data, including assignment of one-half the detection limit to nondetected values or of "fill-in" values randomly selected from an appropriate distribution. On the basis of a limited simulation study, we found that the former approach can be biased unless the percentage of measurements below detection limits is small (5-10%). The fill-in approach generally produces unbiased parameter estimates but may produce biased variance estimates and thereby distort inference when 30% or more of the data are below detection limits. Truncated data methods (e.g., Tobit regression) and multiple imputation offer two unbiased approaches for analyzing measurement data with detection limits. If interest resides solely on regression parameters, then Tobit regression can be used. If individualized values for measurements below detection limits are needed for additional analysis, such as relative risk regression or graphical display, then multiple imputation produces unbiased estimates and nominal confidence intervals unless the proportion of missing data is extreme. We illustrate various approaches using measurements of pesticide residues in carpet dust in control subjects from a case-control study of non-Hodgkin lymphoma. JF - Environmental Health Perspectives AU - Lubin, Jay H AU - Colt, Joanne S AU - Camann, David AU - Davis, Scott Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1691 EP - 1696 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - non-Hodgkin's lymphoma KW - environmental factors KW - Pesticide residues KW - Simulation KW - Dust KW - ENA 09:Land Use & Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21424273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Epidemiologic+Evaluation+of+Measurement+Data+in+the+Presence+of+Detection+Limits&rft.au=Lubin%2C+Jay+H%3BColt%2C+Joanne+S%3BCamann%2C+David%3BDavis%2C+Scott&rft.aulast=Lubin&rft.aufirst=Jay&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1691&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - non-Hodgkin's lymphoma; environmental factors; Pesticide residues; Simulation; Dust ER - TY - JOUR T1 - Is Environmental Health a Basic Human Right? AN - 21423506; 12425439 AB - Who truly owns natural resources such as the water, the air, and the forests? In some areas, courts are ruling that such resources are the property of the people, while others areas bow to free market forces. As the world's population grows greater, resources grow scarcer, and the link between civil instability and environmental degradation becomes clearer, deciding who owns our planet will become less a theoretical exercise to be pondered at leisure than a determination that is deferred at the peril of our survival. JF - Environmental Health Perspectives AU - Taylor, David A Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A1006 EP - A1009 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Environmental degradation KW - world population KW - Human rights KW - Natural resources KW - courts KW - Forests KW - Environmental health KW - survival KW - ENA 13:Population Planning & Control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423506?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Is+Environmental+Health+a+Basic+Human+Right%3F&rft.au=Taylor%2C+David+A&rft.aulast=Taylor&rft.aufirst=David&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A1006&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Environmental degradation; world population; Human rights; courts; Natural resources; Environmental health; Forests; survival ER - TY - JOUR T1 - Battle Scars: Global Conflicts and Environmental Health AN - 21423466; 12425438 AB - The nature and weapons of war have changed radically in the last century, bringing conflict off the battleground and into city streets, and thereby magnifying its environmental health consequences. Age-old problems still follow war---lack of food, shelter, water, and sanitation, risk of infectious disease, and psychological trauma. But modern war also saddles populations with new threats from industrial and military chemicals, pesticides, and radiation, and humanitarian aid systems designed to help people after natural disasters cannot function properly in combat environments. A few encouraging strides are being made, such as the overall reduction in landmine production and use. It remains to be seen what further progress can be made in alleviating the environmental health disaster that is war. JF - Environmental Health Perspectives AU - Brown, Valerie J Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A994 EP - 1003 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - conflicts KW - Chemicals KW - Weapons KW - landmines KW - natural disasters KW - Pesticides KW - Environmental health KW - Military KW - war KW - ENA 09:Land Use & Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Battle+Scars%3A+Global+Conflicts+and+Environmental+Health&rft.au=Brown%2C+Valerie+J&rft.aulast=Brown&rft.aufirst=Valerie&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A994&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Chemicals; conflicts; Weapons; natural disasters; landmines; Pesticides; Environmental health; Military; war ER - TY - JOUR T1 - Effects of Loud Noise Exposure on DNA Integrity in Rat Adrenal Gland AN - 21418243; 12425435 AB - Loud noise is generally considered an environmental stressor causing negative effects on acoustic, cardiovascular, nervous, and endocrine systems. In this study, we investigated the effects of noise exposure on DNA integrity in rat adrenal gland evaluated by the comet assay. The exposure to loud noise (100 dBA) for 12 hr caused a significant increase of DNA damage in the adrenal gland. Genetic alterations did not decrease 24 hr after the cessation of the stimulus. We hypothesize that an imbalance of redox cell status is responsible for the induction and persistence of noise-induced cellular damage. JF - Environmental Health Perspectives AU - Frenzilli, Giada AU - Lenzi, Paola AU - Scarcelli, Vittoria AU - Fornai, Francesco Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1671 EP - 1672 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - environmental stress KW - Acoustics KW - Noise levels KW - DNA KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21418243?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+Loud+Noise+Exposure+on+DNA+Integrity+in+Rat+Adrenal+Gland&rft.au=Frenzilli%2C+Giada%3BLenzi%2C+Paola%3BScarcelli%2C+Vittoria%3BFornai%2C+Francesco&rft.aulast=Frenzilli&rft.aufirst=Giada&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1671&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Acoustics; environmental stress; DNA; Noise levels ER - TY - JOUR T1 - Long-Term Exposure to Environmental Concentrations of the Pharmaceutical Ethynylestradiol Causes Reproductive Failure in Fish AN - 21407686; 12425443 AB - Heightened concern over endocrine-disrupting chemicals is driven by the hypothesis that they could reduce reproductive success and affect wildlife populations, but there is little evidence for this expectation. The pharmaceutical ethynylestradiol (EE2) is a potent endocrine modulator and is present in the aquatic environment at biologically active concentrations. To investigate impacts on reproductive success and mechanisms of disruption, we exposed breeding populations (n = 12) of zebrafish (Danio rerio) over multiple generations to environmentally relevant concentrations of EE2. Life-long exposure to 5 ng/L EE2 in the F1 generation caused a 56% reduction in fecundity and complete population failure with no fertilization. Conversely, the same level of exposure for up to 40 days in mature adults in the parental F0 generation had no impact on reproductive success. Infertility in the F1 generation after life-long exposure to 5 ng/L EE2 was due to disturbed sexual differentiation, with males having no functional testes and either undifferentiated or intersex gonads. These F1 males also showed a reduced vitellogenic response when compared with F0 males, indicating an acclimation to EE2 exposure. Depuration studies found only a partial recovery in reproductive capacity after 5 months. Significantly, even though the F1 males lacked functional testes, they showed male-pattern reproductive behavior, inducing the spawning act and competing with healthy males to disrupt fertilization. Endocrine disruption is therefore likely to affect breeding dynamics and reproductive success in group-spawning fish. Our findings raise major concerns about the population-level impacts for wildlife of long-term exposure to low concentrations of estrogenic endocrine disruptors. JF - Environmental Health Perspectives AU - Nash, Jon P AU - Kime, David E AU - Van der Ven, Leo T M AU - Wester, Piet W Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1725 EP - 1733 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - Chemicals KW - Testes KW - endocrine disruptors KW - Animal reproductive organs KW - Wildlife KW - Spawning KW - Freshwater KW - Freshwater fish KW - Sex hormones KW - fecundity KW - Danio rerio KW - fertilization KW - breeding KW - Fish physiology KW - Endocrinology KW - Reproduction KW - Fish KW - Drugs KW - estrogens KW - Breeding success KW - Q5 08504:Effects on organisms KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21407686?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Long-Term+Exposure+to+Environmental+Concentrations+of+the+Pharmaceutical+Ethynylestradiol+Causes+Reproductive+Failure+in+Fish&rft.au=Nash%2C+Jon+P%3BKime%2C+David+E%3BVan+der+Ven%2C+Leo+T+M%3BWester%2C+Piet+W&rft.aulast=Nash&rft.aufirst=Jon&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1725&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Testes; Fish physiology; Animal reproductive organs; Endocrinology; Spawning; Freshwater fish; Drugs; Sex hormones; Breeding success; Chemicals; fecundity; fertilization; breeding; endocrine disruptors; Wildlife; Fish; Reproduction; estrogens; Danio rerio; Freshwater ER - TY - JOUR T1 - Forum. AN - 21407078; 12421262 AB - Short articles on the following topics: NRDC Knocks Nukes; NAFTA Worries in Juarez; Flu, Fetuses, and Schizophrenia; A Better Model for PD; EHPnet: POV's Borders: Environment; The Beat. JF - Environmental Health Perspectives AU - R, Chepesiuk AU - R, Dahl AU - J, Wakefield AU - H, Heimer AU - EE, Dooley Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A984 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - mental disorders KW - Fetuses KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21407078?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Forum.&rft.au=R%2C+Chepesiuk%3BR%2C+Dahl%3BJ%2C+Wakefield%3BH%2C+Heimer%3BEE%2C+Dooley&rft.aulast=R&rft.aufirst=Chepesiuk&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A984&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - mental disorders; Fetuses ER - TY - JOUR T1 - Prospective Study of Blood and Tibia Lead in Women Undergoing Surgical Menopause AN - 21400429; 12425449 AB - Despite the dramatic decline in environmental lead exposure in the United States during the past couple of decades, concern has been expressed regarding mobilization during menopause of existing lead stored in bone. To investigate whether bone lead concentrations decrease and blood lead levels increase, we conducted a prospective study of 91 women who were scheduled to undergo a bilateral oophorectomy for a benign condition at Mount Sinai Hospital in New York City during October 1994 through April 1999. We excluded women who were younger than 30 years of age or who were postmenopausal at the time of the surgery. We observed a small but significant increase in median blood lead levels between the baseline visit and the 6-month visit (0.4 microg/dL, p0.0001), particularly for women who were not on estrogen replacement therapy (0.7 microg/dL, p=0.008). No significant change was observed in blood lead values between 6 and 18 months postsurgery, nor was there evidence of significant changes in tibia lead concentrations during the follow-up period. These findings do not point to substantial mobilization of lead from cortical bone during menopause. JF - Environmental Health Perspectives AU - Berkowitz, Gertrud S AU - Wolff, Mary S AU - Lapinski, Robert H AU - Todd, Andrew C Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1673 EP - 1678 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Bone KW - Egypt, Arab Rep., Sinai Peninsula KW - USA, New York, New York City KW - post-menopause KW - menopause KW - estrogen replacement therapy KW - Females KW - Lead KW - surgery KW - Blood levels KW - Hospitals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21400429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prospective+Study+of+Blood+and+Tibia+Lead+in+Women+Undergoing+Surgical+Menopause&rft.au=Berkowitz%2C+Gertrud+S%3BWolff%2C+Mary+S%3BLapinski%2C+Robert+H%3BTodd%2C+Andrew+C&rft.aulast=Berkowitz&rft.aufirst=Gertrud&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1673&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Bone; post-menopause; estrogen replacement therapy; menopause; Females; surgery; Lead; Hospitals; Blood levels; USA, New York, New York City; Egypt, Arab Rep., Sinai Peninsula ER - TY - JOUR T1 - Correspondence: PBDEs: Sjodin's Response. AN - 21398564; 12421264 AB - I appreciate Cleet's response to our paper concerning time trends of polybrominated diphenyl ethers (PBDEs) and related compounds in the U.S. population (Sjodin et al. 2004), and I appreciate the opportunity to address his comments. JF - Environmental Health Perspectives AU - A, Sjodin Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - a979 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Polybrominated diphenyl ethers KW - USA KW - polybrominated diphenyl ethers KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21398564?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+PBDEs%3A+Sjodin%27s+Response.&rft.au=A%2C+Sjodin&rft.aulast=A&rft.aufirst=Sjodin&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=a979&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Polybrominated diphenyl ethers; polybrominated diphenyl ethers; USA ER - TY - JOUR T1 - Correspondence: mercury levels in mothers. AN - 21389533; 12421266 AB - I read with great interest the excellent article by Mahaffey et al. (2004), which further describes the characteristics of the 1,709 women from the National Health and Nutrition Examination Survey (NHANES) 1999-2000 who were sampled for total and organic mercury levels in blood. It adds valuable detail to the initial report published last year (Schober et al. 2003). I would appreciate clarification on one important point: in the "Discussion," the authors cited a new analysis which indicates that the cord blood: maternal blood ratio is not 1:1 as assumed by the National Research Council (NRC) in 2000 (Committee on the Toxicological Effects of Methylmercury 2000), but rather 1.7:1. Using the same benchmark dose lower limit and uncertainty factor used by the NRC, Mahaffey et al. (2004) calculated that blood total mercury levels 3.5 microg/L in mothers could be associated with increased risk to the developing fetal nervous system. I am very interested in the details of this analysis and particularly in understanding why the uncertainty factor applied by the NRC to account in part for toxicokinetic variability does not compensate for uncertainty related to the cord blood:maternal blood mercury ratio. This is a critical concept because it has a dramatic impact on how many women may carry mercury levels in excess of what is believed to be safe for a fetus. JF - Environmental Health Perspectives AU - KM, Shea Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A978 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Methylmercury KW - benchmarks KW - Mercury KW - committees KW - Nutrition KW - Blood levels KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21389533?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+mercury+levels+in+mothers.&rft.au=KM%2C+Shea&rft.aulast=KM&rft.aufirst=Shea&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A978&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Methylmercury; benchmarks; committees; Mercury; Nutrition; Blood levels ER - TY - JOUR T1 - Sex and Ceruloplasmin Modulate the Response to Copper Exposure in Healthy Individuals AN - 21384095; 12425447 AB - Previous studies indicated that sex might influence the response to copper exposure. Ceruloplasmin (Cp) is an indicator of Cu status, but it is not clear whether and how it reflects changes of Cu status among healthy individuals. In this study, 82 apparently healthy women and men were chosen from 800 individuals because their Cp values belonged to the higher and lower 10% of the group Cp distribution curve. Before and after receiving a supplement of 10mg Cu/day (upper limit of daily intake) for 2 months, we performed blood and urinary biochemical measurement of potential Cu markers. We used principal component analysis and linear discriminant analysis to identify blood and/or urinary Cu indicators that showed a differential response to copper. Results showed that Cp values in serum represent a reliable indicator to differentiate subgroups within the normal population in their response to Cu exposure. The response depends on Cp values and on sex, such that women with higher and men with lower Cp values exhibit the greatest response. JF - Environmental Health Perspectives AU - Mendez, Marco A AU - Araya, Magdalena AU - Olivares, Manuel AU - Pizarro, Fernando AU - Gonzalez, Mauricio Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1654 EP - 1657 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Biochemistry KW - Urine KW - principal components analysis KW - Copper KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21384095?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Sex+and+Ceruloplasmin+Modulate+the+Response+to+Copper+Exposure+in+Healthy+Individuals&rft.au=Mendez%2C+Marco+A%3BAraya%2C+Magdalena%3BOlivares%2C+Manuel%3BPizarro%2C+Fernando%3BGonzalez%2C+Mauricio&rft.aulast=Mendez&rft.aufirst=Marco&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1654&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Biochemistry; principal components analysis; Urine; Copper ER - TY - JOUR T1 - Correspondence: The Human Population: Accepting Earth's Limitations. AN - 21375285; 12421265 AB - I thank Fowler and Hobbs for their letter (2004) and their research (2003). The view that a complexity of factors impacts human population growth certainly makes sense, and they have correctly pointed out that scientifically organized efforts to deal with human problems must take account of manifold interconnected events. Although it is necessary to recognize and acknowledge the complexities inherent in cultural life and the natural world, it is equally important that a dizzying array of variables not blind us to certain scientific facts of biophysical reality. Humankind is bound by such predominant facts because the workings of the world exist independently of human wishes and beliefs. JF - Environmental Health Perspectives AU - SE, Salmony Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A979 EP - A980 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - human populations KW - culture KW - ENA 13:Population Planning & Control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21375285?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Correspondence%3A+The+Human+Population%3A+Accepting+Earth%27s+Limitations.&rft.au=SE%2C+Salmony&rft.aulast=SE&rft.aufirst=Salmony&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A979&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - human populations; culture ER - TY - JOUR T1 - NIEHS News. AN - 21368799; 12421261 AB - Short articles on: Ethics in Environmental Health; Symposium Explores Children's Environments; Schwartz Named New NIEHS/NTP Director; Headliners: Air Pollution Impairs Lung Development in Children; Beyond the Bench: Help Instead of Hype. JF - Environmental Health Perspectives AU - T, Adler AU - MM, Dimes AU - J, Phelps AU - EE, Dooley Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - A990 EP - A992 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Air pollution KW - Lung KW - Pollution effects KW - Environmental health KW - Children KW - environmental ethics KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21368799?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=NIEHS+News.&rft.au=T%2C+Adler%3BMM%2C+Dimes%3BJ%2C+Phelps%3BEE%2C+Dooley&rft.aulast=T&rft.aufirst=Adler&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=A990&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Air pollution; Lung; Environmental health; Pollution effects; Children; environmental ethics ER - TY - JOUR T1 - SHRIMP U-Pb detrital zircon ages from Proterozoic and Early Palaeozoic sandstones and their bearing on the early geological evolution of Tasmania AN - 21339904; 6254218 AB - Detrital zircons from 13 Late Mesoproterozoic to Early Neoproterozoic sandstones and two Palaeozoic sandstones from Tasmania were dated in order to improve constraints on depositional ages, to test correlation between Proterozoic inliers, and to characterise source regions. These include successions considered to be the oldest presently exposed in Tasmania. Typical features of the age distributions of the Proterozoic rocks are prominent data concentrations at 1800-1650 Ma and 1450-1400 Ma, and a minor spread of Archaean ages. Statistical testing of the similarity of the age profiles shows that widespread quartzarenaceous samples from the Detention Subgroup, Needles Quartzite and from the Tyennan region are strongly similar, consistent with broad correlation. Relatively large differences are seen between the Detention Subgroup and the conformable, stratigraphically higher Jacob Quartzite, which contains an additional spread of 1300-1000 Ma zircons suggestive of a Grenvillian source. Age profiles of the quartzarenites and quartzwacke turbidites (Oonah Formation and correlatives) cannot be readily differentiated. The Oonah Formation likewise includes samples with and without Grenvillian ages, and there is no 750 Ma zircon population that would be expected if the turbidites were genetically related to the Wickham Orogeny. The simplest interpretation is that the quartzarenites (Rocky Cape Group and correlatives) and the turbidites (Oonah Formation and correlates) are lateral equivalents, although a younger (post-Wickham Orogeny) age for the Oonah Formation cannot be discounted. A maximum age of ca 1000 Ma is inferred for the Oonah Formation, Rocky Cape Group and correlatives. A minimum age of ca 750 Ma is provided by the basal age of the overlying Togari Group and correlatives. In a metasediment from western King Island, the youngest detrital zircons are ca 1350 Ma, allowing a pre-Grenvillian depositional age as suggested by previous dating of metamorphic monazite. However, the age profile of this sample is not dissimilar to the other Tasmanian successions that are inferred to be 1000-750 Ma. The Wings Sandstone, of southern Tasmania, contains an unusual profile dominated by Grenvillian ages, consistent with an allochthonous origin. Basement ages that broadly match the age spectra of the Tasmanian Proterozoic sediments are found in southwestern Laurentia, consistent with mutual proximity in Rodinia reconstructions. The Palaeozoic sandstones, from the turbiditic Mathinna Supergroup of northeastern Tasmania, have zircon age profiles typical of the Lachlan Fold Belt, with a predominant latest Neoproterozoic-Early Cambrian component and a lesser, broad Proterozoic data concentration at ca 1000 Ma. Western Tasmania was not a significant part of the source area for these rocks. JF - Australian Journal of Earth Sciences AU - Black, L P AU - Calver, C R AU - Seymour, D B AU - Reed, A AD - Minerals Division, Geoscience Australia, GPO Box 378, Canberra, ACT 2601, Australia; and Research School of Earth Sciences, Australian National University, ACT 0200, Australia Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 885 EP - 900 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 51 IS - 6 SN - 0812-0099, 0812-0099 KW - Microbiology Abstracts B: Bacteriology KW - Age KW - Data processing KW - Statistics KW - Islands KW - Dating KW - Wings KW - Succession KW - Evolution KW - Sediments KW - J 02410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21339904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Earth+Sciences&rft.atitle=SHRIMP+U-Pb+detrital+zircon+ages+from+Proterozoic+and+Early+Palaeozoic+sandstones+and+their+bearing+on+the+early+geological+evolution+of+Tasmania&rft.au=Wallace%2C+C+S%3BReitzenstein%2C+J%3BWithers%2C+G+S&rft.aulast=Wallace&rft.aufirst=C&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1294&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6088 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - SuppNotes - Figures, 5; tables, 1; references, 75. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Age; Islands; Statistics; Data processing; Dating; Wings; Succession; Sediments; Evolution DO - http://dx.doi.org/10.1111/j.1400-0952.2004.01091.x ER - TY - JOUR T1 - Fracture systems in granite pavements of the eastern Pilbara Craton, Western Australia: indicators of neotectonic activity? AN - 21339820; 6254215 AB - Continental Australia is characterised by high levels of seismic activity in comparison with intracratonic areas worldwide. However, the link between earthquake events and earthquake-related geomorphology in Australia remains poorly understood for all except the largest events, because landscape impact unambiguously attributable to seismic activity is difficult to recognise. In this context, we describe several unusual fracture systems of possible tectonic origin that transect granite pavements in the Archaean eastern Pilbara Craton of Western Australia. Occurring at four localities (Gallery Hill, North Shaw, Mulgandinnah Hill and Muccan) separated by up to 150 km, the fracture systems typically range up to 100 m in length and 20 m in width, locally offset pavement surfaces by up to 15 cm vertically, and expose uniformly fresh-looking rock. At one locality (Muccan), the fractures cross-cut two out of three generations of aboriginal petroglyphs etched into the pavement surface, which suggests that fracture formation occurred both recently and rapidly. All four localities are characterised by extensional structures (tension fractures and dilated joints) striking 020-040, and three preserve compressional structures (steeply dipping reverse faults at Gallery Hill and North Shaw; A-tent crestal fractures at Mulgandinnah Hill) trending 100-135. The strongly correlated alignments of the fracture systems militate against a purely weathering-controlled origin, and the observed pattern is compatible with fracture formation in a single East Pilbara-wide stress field, dominated by pure shear and characterised by northeast-southwest- to north-northeast-south-southwest-directed horizontal compression. This orientation is consistent with that derived by spatial averaging of existing stress orientation data from northwest Australia. These preliminary results have exciting implications for the inexpensive field-based determination of regional stress orientation, and for the use of granitic landforms in probabilistic seismic hazard assessment and the identification of earthquake-prone areas. JF - Australian Journal of Earth Sciences AU - Clark, D J AU - Bodorkos, S AD - Geoscience Australia, GPO Box 378, Canberra, ACT 2601, Australia Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 831 EP - 846 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 51 IS - 6 SN - 0812-0099, 0812-0099 KW - Microbiology Abstracts B: Bacteriology KW - Galleries KW - Earthquakes KW - Geomorphology KW - Data processing KW - Landscape KW - Fractures KW - Stress KW - Joints KW - Compression KW - J 02490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21339820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Earth+Sciences&rft.atitle=Fracture+systems+in+granite+pavements+of+the+eastern+Pilbara+Craton%2C+Western+Australia%3A+indicators+of+neotectonic+activity%3F&rft.au=Clark%2C+D+J%3BBodorkos%2C+S&rft.aulast=Clark&rft.aufirst=D&rft.date=2004-12-01&rft.volume=51&rft.issue=6&rft.spage=831&rft.isbn=&rft.btitle=&rft.title=Australian+Journal+of+Earth+Sciences&rft.issn=08120099&rft_id=info:doi/10.1111%2Fj.1400-0952.2004.01088.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - SuppNotes - Figures, 11; tables, 1; references, 52. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Earthquakes; Galleries; Data processing; Geomorphology; Landscape; Fractures; Stress; Compression; Joints DO - http://dx.doi.org/10.1111/j.1400-0952.2004.01088.x ER - TY - JOUR T1 - Late Miocene (U+Th)- super(4)He ages of ferruginous nodules from lateritic duricrust, Darling Range, Western Australia AN - 21335950; 6254219 AB - (U+Th)- super(4)He dates are presented for hematite-maghemite and hematite separates from pisolitic nodules from four rock specimens of lateritic duricrust sampled in an area of about 1 km super(2) in the Darling Range about 50 km northeast of Perth, where the duricrust forms a continuous cover over rocks of the Archaean Yilgarn Craton. Textures and compositions of the separates were checked by X-ray diffraction and scanning electron microscopy. Hematite-maghemite separates from three of the specimens yielded ages of about 10 Ma, identical within error (weighted mean, 9.9 c 0.9 Ma, 2s), whereas the hematite separate from the fourth specimen gave a U-He date of 7.5 Ma, all within the Late Miocene. While questions remain as to whether initial and boundary conditions of dating are adequately fulfilled, the iron oxide super(4)He dates are in good agreement with estimates by palaeomagnetic dating and other methods for the age of laterite formation in the Darling Range and other parts of south Western Australia. This study demonstrates the potential of (U+Th)- super(4)He dating as a serviceable, directly applicable tool for dating lateritic duricrust. JF - Australian Journal of Earth Sciences AU - Pidgeon, R T AU - Brander, T AU - Lippolt, HJ AD - Department of Applied Geology, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia, r.pidgeon@curtin.edu.au Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 901 EP - 909 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 51 IS - 6 SN - 0812-0099, 0812-0099 KW - Microbiology Abstracts B: Bacteriology KW - Scanning electron microscopy KW - Age KW - iron oxides KW - Dating KW - Boundaries KW - X-ray diffraction KW - Nodules KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21335950?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Earth+Sciences&rft.atitle=Late+Miocene+%28U%2BTh%29-+super%284%29He+ages+of+ferruginous+nodules+from+lateritic+duricrust%2C+Darling+Range%2C+Western+Australia&rft.au=Osornio-Vargas%2C+A+R%3BBonner%2C+J+C%3BAlfaro-Moreno%2C+E%3BMartinez%2C+L%3BGarcia-Cuellar%2C+C%3BPonce-de-Leon+Rosales%2C+S%3BMiranda%2C+J%3BRosas%2C+I&rft.aulast=Osornio-Vargas&rft.aufirst=A&rft.date=2003-08-01&rft.volume=111&rft.issue=10&rft.spage=1289&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5913 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - SuppNotes - Figures, 4; tables, 1; references, 63. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Scanning electron microscopy; Age; iron oxides; Dating; Boundaries; X-ray diffraction; Nodules DO - http://dx.doi.org/10.1111/j.1400-0952.2004.01094.x ER - TY - JOUR T1 - Sediment transport in distributary channels and its export to the pro-deltaic environment in a tidally dominated delta: Fly River, Papua New Guinea AN - 21000758; 7489943 AB - Current metre deployments, suspended sediment measurements and surface sediment samples were collected from three locations within distributary channels of the tidally dominated Fly River delta in southern Papua New Guinea. Net bedload transport vectors and the occurrence of elongate tidal bars indicate that mutually evasive ebb- and flood-dominant transport zones occur in each of the distributary channels. Suspended sediment experiments at two locations show a phase relationship between tidal velocity and sediment concentration such that the net suspended sediment flux is directed seaward. Processes that control the export of fluid muds with concentrations up to 10gl-1 from the distributary channels across the delta front and onto the pro-delta are assessed in relation to the available data. Peak spring tidal current speeds (measured at 100cm above the bed) drop off from around 100cms-1 within the distributary channels to <50cms-1 on the delta front. Gravity-driven, 2-m thick, fluid mud layers generated in the distributary channels are estimated to require at least 35h to traverse the 20-km-wide, low-gradient (2X10-3 degrees) delta front. The velocities of such currents are well below those required for autosuspension. A 1-month time series of suspended sediment concentration and current velocity from the delta front indicates that tidal currents alone are unable to cause significant cross-delta mud transport. Wave-induced resuspension together with tides, storm surge and barotropic return-flow may play a role in maintaining the transport of fine sediment across the delta front, but insufficient data are available at present to make any reliable estimates. JF - Continental Shelf Research AU - Harris, Peter T AU - Hughes, Michael G AU - Baker, Elaine K AU - Dalrymple, Robert W AU - Keene, Jock B AD - Marine and Coastal Environment Group Geoscience Australia, GPO Box 378, Canberra, ACT 2601, Australia, Peter.Harris@ga.gov.au Y1 - 2004/12// PY - 2004 DA - December 2004 SP - 2431 EP - 2454 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 24 IS - 19 SN - 0278-4343, 0278-4343 KW - Aqualine Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts; Oceanic Abstracts KW - Bedload KW - Sediment transport KW - Suspended load KW - Autosuspension KW - Hyperpycnal flow KW - Turbidity KW - Mutually evasive KW - Deltaic KW - Tide-dominated KW - Deltas KW - Time series analysis KW - Resuspended sediments KW - Fluid mud KW - Continental shelves KW - Papua New Guinea, Fly R. KW - Sedimentation KW - Sediment Transport KW - Rivers KW - Suspended Sediments KW - Mud KW - Velocity KW - Export KW - Tidal currents KW - Channels KW - Sediment-water interface KW - Suspended matter in seawater KW - Fronts KW - Storm surges KW - Tidal Currents KW - ISEW, Papua New Guinea KW - AQ 00001:Water Resources and Supplies KW - Q2 09264:Sediments and sedimentation KW - SW 0835:Streamflow and runoff KW - O 3050:Sediment Dynamics KW - M2 551.466:Ocean Waves and Tides (551.466) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21000758?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Continental+Shelf+Research&rft.atitle=Sediment+transport+in+distributary+channels+and+its+export+to+the+pro-deltaic+environment+in+a+tidally+dominated+delta%3A+Fly+River%2C+Papua+New+Guinea&rft.au=Harris%2C+Peter+T%3BHughes%2C+Michael+G%3BBaker%2C+Elaine+K%3BDalrymple%2C+Robert+W%3BKeene%2C+Jock+B&rft.aulast=Harris&rft.aufirst=Peter&rft.date=2004-12-01&rft.volume=24&rft.issue=19&rft.spage=2431&rft.isbn=&rft.btitle=&rft.title=Continental+Shelf+Research&rft.issn=02784343&rft_id=info:doi/10.1016%2Fj.csr.2004.07.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Rivers; Resuspended sediments; Sediment-water interface; Fluid mud; Storm surges; Continental shelves; Sediment transport; Deltas; Sedimentation; Suspended matter in seawater; Fronts; Time series analysis; Tidal currents; Sediment Transport; Channels; Suspended Sediments; Tidal Currents; Velocity; Mud; Export; Papua New Guinea, Fly R.; ISEW, Papua New Guinea DO - http://dx.doi.org/10.1016/j.csr.2004.07.017 ER - TY - JOUR T1 - Estimated change in physical activity level (PAL) and prediction of 5-year weight change in men: the Aerobics Center Longitudinal Study AN - 17791719; 6111111 AB - To determine the relation between the average daily physical activity level (PAL) and the trajectory of weight change in men at risk for weight gain. Clinic-based cohort study over an average of 5 y. Healthy men (N = 2501) ages 20-55 y participating in the Aerobics Center Longitudinal Study who had received at least four medical examinations at the Cooper Clinic between 1970 and 1998. Daily leisure-time physical activity was reported and body weight was measured at all four examinations. The average daily PAL (METs 24 h super(-1)) was estimated from all activities, as well as from other incidental active and passive activities. Weight change over four examinations was regressed on the change in PAL between the first and third examinations. Random coefficient regression modeling indicated a curvilinear slope for weight gain over the follow-up among those maintaining the same PAL between the first and third examinations. Weight gain was further accelerated among men who decreased their activity. A shift from a low PAL ( 1.60 METs 24 h super(-1)) PAL was necessary for weight loss over time. Men with initially the lowest PAL had the greatest benefit from increasing activity. Daily PAL was inversely related to weight gain in this cohort. Increasing to or maintaining a daily PAL at least 60% above the resting metabolic rate (ie, PAL > 1.60 METs 24 h super(-1)) may be necessary to maintain body weight in middle-age and can be achieved by incorporating 45-60 min of brisk walking, gardening/yardwork, or cycling into the daily routine. JF - International Journal of Obesity AU - Di Pietro, L AU - Dziura, J AU - Blair, S N AD - John B. Pierce Laboratory, Yale University School of Medicine, 290 Congress Avenue, New Haven, CT 06519, USA, ldipietro@jbpierce.org Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1541 EP - 1547 VL - 28 IS - 12 SN - 0307-0565, 0307-0565 KW - Physical Education Index KW - Longitudinal studies KW - Obesity KW - Measurement KW - Weight control KW - Men KW - Walking KW - Basal metabolic rate KW - Exercise KW - Bicycling KW - Evaluation KW - Medical examinations KW - Weight KW - Activities KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17791719?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Obesity&rft.atitle=Estimated+change+in+physical+activity+level+%28PAL%29+and+prediction+of+5-year+weight+change+in+men%3A+the+Aerobics+Center+Longitudinal+Study&rft.au=Di+Pietro%2C+L%3BDziura%2C+J%3BBlair%2C+S+N&rft.aulast=Di+Pietro&rft.aufirst=L&rft.date=2004-12-01&rft.volume=28&rft.issue=12&rft.spage=1541&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Obesity&rft.issn=03070565&rft_id=info:doi/10.1038%2Fsj.ijo.0802821 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Weight; Men; Activities; Evaluation; Exercise; Longitudinal studies; Medical examinations; Weight control; Measurement; Obesity; Basal metabolic rate; Walking; Bicycling DO - http://dx.doi.org/10.1038/sj.ijo.0802821 ER - TY - JOUR T1 - Breeding System in a Population of Trigonella balansae (Leguminosae) AN - 17791282; 6076406 AB - BACKGROUND: and Aims Although some taxonomic studies in the genus Trigonella have been conducted, there has been no concerted effort to study the breeding system. This paper examines the floral structure and pollination system in a population of T. balansae, an annual pasture legume. METHODS: Floral morphology, hand and vector pollination, stigma receptivity, pollen tube growth, using scanning electron and fluorescence microscopy, were conducted. Key Results Measurements of floral structure from before to after anthesis indicates an inability for T. balansae to self-pollinate and a requirement for an external vector to effectively transfer pollen from the anthers onto the stigmas of this species. Seed set can be obtained by hand or honeybee manipulation of T. balansae flowers. CONCLUSIONS: Trigonella balansae is a self-compatible species, but which requires vectors such as honeybees to bring about pollination. JF - Annals of Botany AU - Nair, Ramakrishnan M AU - Dundas, Ian S AU - Wallwork, Meredith AU - Verlin, Dawn C AU - Waterhouse, Lyn AU - Dowling, Kate AD - South Australian Research & Development Institute (SARDI), GPO Box 397, Adelaide, SA 5001, Australia, School of Agriculture and Wine, University of Adelaide, Waite Campus, PMB 1, Glen Osmond, SA 5064, Australia, Adelaide Microscopy, University of Adelaide, Adelaide, SA 5005, Australia and BiometricsSA, SARDI, GPO Box 397, Adelaide, SA 5001, Australia Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 883 EP - 888 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 94 IS - 6 SN - 0305-7364, 0305-7364 KW - Ecology Abstracts KW - Pollination KW - Trigonella balansae KW - Anthers KW - Breeding KW - Legumes KW - Pasture KW - Stigma KW - Pollen KW - Reproductive strategy KW - D 04637:Legumes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17791282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Botany&rft.atitle=Breeding+System+in+a+Population+of+Trigonella+balansae+%28Leguminosae%29&rft.au=Nair%2C+Ramakrishnan+M%3BDundas%2C+Ian+S%3BWallwork%2C+Meredith%3BVerlin%2C+Dawn+C%3BWaterhouse%2C+Lyn%3BDowling%2C+Kate&rft.aulast=Nair&rft.aufirst=Ramakrishnan&rft.date=2004-12-01&rft.volume=94&rft.issue=6&rft.spage=883&rft.isbn=&rft.btitle=&rft.title=Annals+of+Botany&rft.issn=03057364&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Trigonella balansae; Pollination; Stigma; Breeding; Reproductive strategy; Anthers; Legumes; Pasture; Pollen ER - TY - JOUR T1 - Strain- and sex-related differences of carbonyl reductase activities in kidney microsomes and cytosol of rats AN - 17506460; 6403258 AB - This study was designed to elucidate strain- and sex-related differences of carbonyl reductase activity in rat kidney by using the oral antidiabetic drug acetohexamide as substrate. The frequency distribution of carbonyl reductase activities in kidney microsomes of male Fischer 344 (Fischer), Sprague-Dawley, Wistar and Wistar-Imamichi (Wistar-IM) rats exhibited a marked strain-related difference. Furthermore, the enzyme activities in kidney microsomes of Fischer, Sprague-Dawley and Wistar rats were male-specific, resulting in significant sex-related differences in these strains. There was no sex-related difference of carbonyl reductase activity in kidney microsomes of the Wistar-IM strain, which lacked its activity in both sexes. On the other hand, although carbonyl reductase activities were fully detectable in kidney cytosols from all the strains of male and female rats, no strain- or sex-related difference was observed among the cytosolic enzyme activities. These results provide new information for understanding the influence of internal factors on the renal metabolism of ketone-containing xenobiotics. JF - Journal of Applied Toxicology AU - Imamura, Y AU - Shimada, H AD - Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan, yorishig@gpo.kumamoto-u.ac.jp Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 437 EP - 441 VL - 24 IS - 6 SN - 0260-437X, 0260-437X KW - Carbonyl reductase KW - acetohexamide KW - Toxicology Abstracts KW - Microsomes KW - Cytosol KW - Kidney KW - Xenobiotics KW - Sex differences KW - Drugs KW - carbonyls KW - Metabolism KW - X 24117:Biochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17506460?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Toxicology&rft.atitle=Strain-+and+sex-related+differences+of+carbonyl+reductase+activities+in+kidney+microsomes+and+cytosol+of+rats&rft.au=Imamura%2C+Y%3BShimada%2C+H&rft.aulast=Imamura&rft.aufirst=Y&rft.date=2004-12-01&rft.volume=24&rft.issue=6&rft.spage=437&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Toxicology&rft.issn=0260437X&rft_id=info:doi/10.1002%2Fjat.996 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Kidney; Sex differences; carbonyls; Microsomes; Cytosol; Metabolism; Xenobiotics; Drugs DO - http://dx.doi.org/10.1002/jat.996 ER - TY - JOUR T1 - Management of exogenous threats to Antarctica and the sub-Antarctic Islands: balancing risks from TBT and non-indigenous marine organisms AN - 16187558; 6102332 AB - The discovery of high levels of tributyltin compounds in Antarctic marine sediments has prompted managers to consider the banning of such substances in this region. We propose that the banning of antifouling coatings may result in an increase in the risk of non-indigenous species invasions. Our studies show that un-treated vessels carry a more diverse community of fouling organisms than treated hulls on which fouling is restricted to specific untreated niches. Up to 40% of the species recruited to the hulls of Southern Ocean vessels are species with invasive histories. Viable fouling assemblages can survive prolonged voyages to high-latitude coastlines, yet passage through sea-ice may remove fouling communities due to mechanical abrasion reducing the hazard of introductions to ice-bound coastlines. The banning of antifouling compounds may be of particular concern for the ice-free sub-Antarctic islands which represent a common anchorage point for vessels on-route to Antarctica. JF - Marine Pollution Bulletin AU - Lewis, P N AU - Riddle, MJ AU - Hewitt, CL AD - Institute of Antarctic and Southern Ocean Studies (IASOS), University of Tasmania, GPO Box 252-77, Hobart, Tasmania 7001, Australia, plewis@utas.edu.au Y1 - 2004/12// PY - 2004 DA - December 2004 SP - 999 EP - 1005 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 49 IS - 11-12 SN - 0025-326X, 0025-326X KW - invasive species KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources; Toxicology Abstracts; Oceanic Abstracts; Aqualine Abstracts; Water Resources Abstracts; Pollution Abstracts KW - TBT KW - Bioinvasions KW - Antarctica KW - Sub-Antarctic islands KW - Fouling KW - Antifouling KW - Abrasion KW - Niches KW - Antarctic zone KW - Marine Sediments KW - Biota KW - Ship hulls KW - Fouling organisms KW - Ice KW - Tin compounds KW - Anchorages KW - Tributyltin KW - PS, Antarctica KW - Community composition KW - PS, Antarctic Ocean KW - Organotin compounds KW - Dispersion KW - Risk assessment KW - Antarctic KW - Risks KW - Hazards KW - Islands KW - History KW - Ecosystem management KW - Polar waters KW - Marine KW - Toxicity KW - Polar environments KW - Risk KW - Sea ice KW - Fouling control KW - Antifouling substances KW - Oceans KW - Nature conservation KW - Marine organisms KW - Introduced species KW - Coatings KW - Q5 08523:Conservation, wildlife management and recreation KW - O 4090:Conservation and Environmental Protection KW - X 24166:Environmental impact KW - Q2 09181:General KW - P 1000:MARINE POLLUTION KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16187558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Pollution+Bulletin&rft.atitle=Management+of+exogenous+threats+to+Antarctica+and+the+sub-Antarctic+Islands%3A+balancing+risks+from+TBT+and+non-indigenous+marine+organisms&rft.au=Lewis%2C+P+N%3BRiddle%2C+MJ%3BHewitt%2C+CL&rft.aulast=Lewis&rft.aufirst=P&rft.date=2004-12-01&rft.volume=49&rft.issue=11-12&rft.spage=999&rft.isbn=&rft.btitle=&rft.title=Marine+Pollution+Bulletin&rft.issn=0025326X&rft_id=info:doi/10.1016%2Fj.marpolbul.2004.07.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-02-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Tin compounds; Anchorages; Toxicity; Risks; Tributyltin; Hazards; Antarctic zone; Sea ice; Biota; Community composition; Antifouling substances; Fouling control; Nature conservation; Ecosystem management; Polar waters; Marine organisms; Ship hulls; Introduced species; Fouling organisms; Dispersion; Fouling; Risk assessment; Ice; Islands; Polar environments; Organotin compounds; Risk; Marine Sediments; Abrasion; History; Oceans; Niches; Antarctic; Coatings; PS, Antarctica; Antarctica; PS, Antarctic Ocean; Marine DO - http://dx.doi.org/10.1016/j.marpolbul.2004.07.001 ER - TY - JOUR T1 - The Effects of the World Trade Center Event on Birth Outcomes Among Term Deliveries at Three Lower Manhattan Hospitals AN - 14720930; 10672912 AB - Birth outcomes were assessed for women in the New York City area who lived or worked in the vicinity of the World Trade Center (WTC) at the time of the September 2001 terrorist attack and during the following weeks. Data were obtained from three large Lower Manhattan hospitals with maternity units. Results revealed that term infants of women residing within a 2-mi radius of the WTC during the four weeks after the attack weighed, on average, 149 g less than term infants born to women residing outside the area. Infants born to residents were also, on average, 0.82 cm shorter than those born to women living outside the area. No significant association was found for head circumference or for length of gestation, but women who were in the first trimester of pregnancy on September 11 delivered, on average, 3.6 d earlier than women in later stages of pregnancy. JF - Environmental Health Perspectives AU - Lederman, Sally Ann AU - Rauh, Virginia AU - Weiss, Lisa AU - Stein, Janet L AU - Hoepner, Lori A AU - Becker, Mark AU - Perera, Frederica P Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1772 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AREA COMPARISONS KW - BIOMASS KW - REPRODUCTION, HUMAN KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14720930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Effects+of+the+World+Trade+Center+Event+on+Birth+Outcomes+Among+Term+Deliveries+at+Three+Lower+Manhattan+Hospitals&rft.au=Lederman%2C+Sally+Ann%3BRauh%2C+Virginia%3BWeiss%2C+Lisa%3BStein%2C+Janet+L%3BHoepner%2C+Lori+A%3BBecker%2C+Mark%3BPerera%2C+Frederica+P&rft.aulast=Lederman&rft.aufirst=Sally&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1772&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AREA COMPARISONS; BIOMASS; REPRODUCTION, HUMAN; NEW YORK CITY ER - TY - JOUR T1 - Prenatal DDT Exposure in Relation to Anthropometric and Pubertal Measures in Adolescent Males AN - 14718558; 10672910 AB - Selected subjects from the Philadelphia Blood Pressure Project were studied to explore the effects of prenatal exposure to DDTs on anthropometric and pubertal measures in adolescent males. Anthropometric measurements up to 20 yr of age were used, and maternal serum samples from the third trimester were analyzed for DDT concentrations. Results showed that the concentrations of p,p'-DDE in maternal serum during pregnancy ranged 125 mu g/g lipid, while the other two DDT compounds were found at lower levels, but the concentrations of all three compounds were correlated. Results from statistical modeling showed no statistically significant effects of p,p'-DDE, p,p'-DDT, or o,p'-DDT on the anthropometric or pubertal measures in the adolescent males. JF - Environmental Health Perspectives AU - Gladen, Beth C AU - Klebanoff, Mark A AU - Hediger, Mary L AU - Katz, Solomon H AU - Barr, Dana B AU - Davis, Mark D AU - Longnecker, Matthew P Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1761 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - PHYSIOLOGICAL EFFECTS, HUMAN KW - REPRODUCTION, HUMAN KW - DDT KW - DDE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prenatal+DDT+Exposure+in+Relation+to+Anthropometric+and+Pubertal+Measures+in+Adolescent+Males&rft.au=Gladen%2C+Beth+C%3BKlebanoff%2C+Mark+A%3BHediger%2C+Mary+L%3BKatz%2C+Solomon+H%3BBarr%2C+Dana+B%3BDavis%2C+Mark+D%3BLongnecker%2C+Matthew+P&rft.aulast=Gladen&rft.aufirst=Beth&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1761&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; PHYSIOLOGICAL EFFECTS, HUMAN; DDE; DDT; REPRODUCTION, HUMAN ER - TY - JOUR T1 - The Sources of Inflammatory Mediators in the Lung After Silica Exposure AN - 14718543; 10672899 AB - To understand the role of inflammatory mediators in silica-induced pathology, the expression of several inflammatory mediators in alveolar macrophages (AMs) was studies after in vitro exposure to silica or after in vivo exposure by intratracheal instillation. The expression was studied in specific pathogen-free SpragueDawley rats at the message level by real-time reverse transcription polymerase chain reaction and, where appropriate, at the protein level by enzyme-linked immunosorbent assays. In addition, the interactions between AMs and type II cells or fibroblasts were studied in in vitro culture systems. Results showed that exposure of AMs to silica in vitro increased the message levels of only three genes: interleukin-6, monocyte chemoattractant protein-1, and macrophage inflammatory protein-2. In addition, when mRNA levels were measured in bronchoalveolar lavage cells harvested from rats instilled with silica, the mRNA levels of four other genes-granulocyte/macrophage-colony stimulating factor, interleukin-1 beta , interleukin-10, and inducible nitric oxide synthase-also went up. JF - Environmental Health Perspectives AU - Murali Krishna Rao, K AU - Porter, Dale W AU - Meighan, Terence AU - Castranova, Vince Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1679 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - PROTEIN SYNTHESIS KW - PULMONARY EFFECTS KW - SILICON COMPOUNDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718543?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Sources+of+Inflammatory+Mediators+in+the+Lung+After+Silica+Exposure&rft.au=Murali+Krishna+Rao%2C+K%3BPorter%2C+Dale+W%3BMeighan%2C+Terence%3BCastranova%2C+Vince&rft.aulast=Murali+Krishna+Rao&rft.aufirst=K&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1679&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 12 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; PROTEIN SYNTHESIS; PULMONARY EFFECTS; SILICON COMPOUNDS ER - TY - JOUR T1 - Incorporating Environmental Health into Pediatric Medical and Nursing Education AN - 14718487; 10672909 AB - Leading health institutions have called for improvements in the environmental health education for health professionals, and several medical and nursing organizations have supported environmental health education for such professionals by endorsing the Health Professionals and Environmental Health Education Position Statement of the National Environmental Education and Training Foundation. To address the need, two working groups of pediatric physicians and nurses conducted an assessment of and identified points of insertion in the current medical and nursing education structures where environmental health content could be incorporated. These strategic opportunities are identified, providing a comprehensive list of insertion points to guide medical and nursing education accrediting bodies, licensing bodies, and other key personnel who determine and influence medical and nursing curricula. JF - Environmental Health Perspectives AU - McCurdy, Leyla Erk AU - Roberts, James AU - Rogers, Bonnie AU - Love, Rebecca AU - Etzel, Ruth AU - Paulson, Jerome AU - Witherspoon, Nsedu Obot Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1755 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CURRICULUM KW - EDUCATION, UNIVERSITY KW - PUBLIC HEALTH KW - HEALTH, ENV KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718487?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Incorporating+Environmental+Health+into+Pediatric+Medical+and+Nursing+Education&rft.au=McCurdy%2C+Leyla+Erk%3BRoberts%2C+James%3BRogers%2C+Bonnie%3BLove%2C+Rebecca%3BEtzel%2C+Ruth%3BPaulson%2C+Jerome%3BWitherspoon%2C+Nsedu+Obot&rft.aulast=McCurdy&rft.aufirst=Leyla&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1755&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CURRICULUM; EDUCATION, UNIVERSITY; PUBLIC HEALTH; HEALTH, ENV ER - TY - JOUR T1 - Environmental Health Disparities: a Framework Integrating Psychosocial and Environmental Concepts AN - 14718479; 10672894 JF - Environmental Health Perspectives AU - Gee, Gilbert C AU - Payne-Sturges, Devon C Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1645 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SOCIOECONOMIC IMPACT ASSESSMENT KW - PUBLIC HEALTH KW - ECOLOGY, HUMAN KW - CHEMICAL CONTAMINATION KW - ENV QUALITY ASSESSMENT KW - ENV JUSTICE KW - RACIAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718479?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Environmental+Health+Disparities%3A+a+Framework+Integrating+Psychosocial+and+Environmental+Concepts&rft.au=Gee%2C+Gilbert+C%3BPayne-Sturges%2C+Devon+C&rft.aulast=Gee&rft.aufirst=Gilbert&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1645&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOCIOECONOMIC IMPACT ASSESSMENT; ENV JUSTICE; PUBLIC HEALTH; ECOLOGY, HUMAN; RACIAL COMPARISONS; CHEMICAL CONTAMINATION; ENV QUALITY ASSESSMENT ER - TY - JOUR T1 - Pulmonary Epithelial Integrity in Children: Relationship to Ozone Exposure and Swimming Pool Attendance AN - 14718363; 10672911 AB - In Umea, Sweden, pulmonary epithelial integrity in children was studied during May 2002 and related to ozone exposure and swimming-pool attendance. Lung function measurements were performed, and peripheral blood samples were obtained for analysis of Clara cell protein (CC16) in serum. Nearly 40% of the children were regular indoor pool visitors. Outdoor O sub(3) was monitored continuously at the university campus where the children spent time outdoors. Results showed that O sub(3) levels ranged 77116 mu g/m super(3), and the levels did not have any adverse effect on forced expiratory volume in 1 s. Significantly lower levels of serum CC16 were found in pool visitors compared with controls, which suggested adverse effects on Clara cells. No significant differences were found in the levels of CC16 before and after outdoor exercise, and no statistically significant relationships were found between CC16 levels in serum and ambient O sub(3) exposure. JF - Environmental Health Perspectives AU - Lagerkvist, Birgitta Json AU - Bernard, Alfred AU - Blomberg, Anders AU - Bergstrom, Erik AU - Forsberg, Bertil AU - Holmstrom, Karin AU - Karp, Kjell Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1768 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SWEDEN KW - CHLORINATION KW - SWIMMING POOLS KW - PULMONARY EFFECTS KW - OZONE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pulmonary+Epithelial+Integrity+in+Children%3A+Relationship+to+Ozone+Exposure+and+Swimming+Pool+Attendance&rft.au=Lagerkvist%2C+Birgitta+Json%3BBernard%2C+Alfred%3BBlomberg%2C+Anders%3BBergstrom%2C+Erik%3BForsberg%2C+Bertil%3BHolmstrom%2C+Karin%3BKarp%2C+Kjell&rft.aulast=Lagerkvist&rft.aufirst=Birgitta&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1768&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SWEDEN; CHLORINATION; SWIMMING POOLS; PULMONARY EFFECTS; OZONE ER - TY - JOUR T1 - Association of Chromosomal Alterations with Arsenite-Induced Tumorigenicity of Human HaCaT Keratinocytes in Nude Mice AN - 14718033; 10672903 AB - An immortalized but nontumorigenic human skin keratinocyte cell line, HaCaT, was exposed to low-dose inorganic trivalent arsenite for a long period, and conversion of the cells from nontumorigenic to tumorigenic was assessed by injecting the arsenite-exposed cells into nude mice. Chromosomal alterations in the cell lines established from the resulting tumors were analyzed using the comparative genomic hybridization technique. Results showed that the nontumorigenic cells were converted into cells that were tumorigenic. Histology of the tumors showed epithelial hyperplasia, mild dysplasia, severe dysplasia, and invasive carcinoma, which are similar to arsenic-induced skin pathology. Long-term exposure of HaCaT cells to low doses of arsenite resulted in an increase in intracellular glutathione levels and resistance to arsenite challenges. The increased frequency of micronuclei observed in A1 and A2 cells showed that long-term exposure to low-dose arsenite caused chromosomal damage. A gain of chromosome 4q and a loss of chromosome 9q were observed in most of the cell lines established. JF - Environmental Health Perspectives AU - Chien, Chia-Wen AU - Chiang, Ming-Chang AU - Ho, I-Ching AU - Lee, Te-Chang Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1704 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - CYTOTOXICITY KW - ARSENIC KW - TUMORIGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718033?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+of+Chromosomal+Alterations+with+Arsenite-Induced+Tumorigenicity+of+Human+HaCaT+Keratinocytes+in+Nude+Mice&rft.au=Chien%2C+Chia-Wen%3BChiang%2C+Ming-Chang%3BHo%2C+I-Ching%3BLee%2C+Te-Chang&rft.aulast=Chien&rft.aufirst=Chia-Wen&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1704&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; CYTOTOXICITY; ARSENIC; TUMORIGENIC AGENTS ER - TY - JOUR T1 - GIS Modeling of Air Toxics Releases from TRI-Reporting and Non-TRI-Reporting Facilities: Impacts for Environmental Justice AN - 14717522; 10672905 AB - Air toxics releases from Toxic Release Inventory (TRI)-reporting and -nonreporting facilities were modeled using dispersion modeling and geographic information system (GIS) analysis at four levels of geographic resolution. The study region was Durham County, NC, which represents a broad range of values across demographic, socioeconomic, and social indicators. The four geographic levels were ZIP code, census tract, census block group, and census block. An employee-based emissions algorithm was generated to impute emissions to TRI-nonreporting facilities. Results indicated that the inclusive modeling of all facilities significantly altered the magnitude and spatial distribution of modeled air concentrations, as modeling all sites together, rather than modeling TRI sites alone, increased the magnitude of the modeled concentrations, especially in areas with no TRI facilities. JF - Environmental Health Perspectives AU - Dolinoy, Dana C AU - Miranda, Marie Lynn Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1717 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MATHEMATIC MODELS, AIR KW - SPATIAL COMPARISONS KW - NORTH CAROLINA KW - AIR TOXICS KW - DATA REPORTING, MANDATORY KW - ENV JUSTICE KW - STACK EMISSIONS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14717522?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=GIS+Modeling+of+Air+Toxics+Releases+from+TRI-Reporting+and+Non-TRI-Reporting+Facilities%3A+Impacts+for+Environmental+Justice&rft.au=Dolinoy%2C+Dana+C%3BMiranda%2C+Marie+Lynn&rft.aulast=Dolinoy&rft.aufirst=Dana&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1717&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV JUSTICE; MATHEMATIC MODELS, AIR; GEOGRAPHIC INFORMATION SYSTEMS; STACK EMISSIONS; NORTH CAROLINA; SPATIAL COMPARISONS; AIR TOXICS; DATA REPORTING, MANDATORY ER - TY - JOUR T1 - Use of Pharmacokinetic Modeling to Design Studies for Pathway-Specific Exposure Model Evaluation AN - 14716498; 10672902 AB - Pharmacokinetic modeling was used to guide the design of a field study to evaluate a pathway-specific model using urinary metabolites measured in overnight voids of children. The children's dietary intake model for pesticide exposure was used. The major problem in assessing children's dietary exposure is that young children often touch foods with their hands before consumption, which increases the contamination of the food and their intake of contaminants through the diet. Computer simulation results indicated three important aspects for a successful design: longitudinal design of the study, short half-life of the selected chemical, and high pesticide surface loading. The results showed that the use of pharmacokinetic modeling can allow better planning of field efforts to collect data, as well as reduce the study costs. JF - Environmental Health Perspectives AU - Hu, Ye AU - Akland, Gerry G AU - Pellizzari, Edo D AU - Berry, Maurice R AU - Melnyk, Lisa Jo Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1697 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DESIGN KW - DIET KW - MATHEMATIC MODELS, BIOLOGICAL KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716498?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Use+of+Pharmacokinetic+Modeling+to+Design+Studies+for+Pathway-Specific+Exposure+Model+Evaluation&rft.au=Hu%2C+Ye%3BAkland%2C+Gerry+G%3BPellizzari%2C+Edo+D%3BBerry%2C+Maurice+R%3BMelnyk%2C+Lisa+Jo&rft.aulast=Hu&rft.aufirst=Ye&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1697&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DESIGN; DIET; MATHEMATIC MODELS, BIOLOGICAL; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Estimating the Independent Effects of Multiple Pollutants in the Presence of Measurement Error: an Application of a Measurement-Error-Resistant Technique AN - 14716452; 10672900 AB - An approach has been developed recently that uses hierarchical modeling to assess exposurehealth outcome associations, which is resistant to exposure measurement error. The method was used to examine the independent effects of PM sub(10) and several gaseous air pollutants on daily deaths, using recent data and results from the National Mortality and Morbidity Air Pollution Study conducted across 90 US cities. The hierarchical model is provided. When averaged over the results for each different pollutant, important associations appeared for PM sub(10) and carbon monoxide. For sulfur dioxide, the effects were found to vary greatly, with an overall estimate of 0.1% increase in daily mortality, while no effect on daily mortality was found for nitrogen dioxide. JF - Environmental Health Perspectives AU - Zeka, Ariana AU - Schwartz, Joel Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1686 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SULFUR DIOXIDE KW - NITROGEN DIOXIDE KW - AIR POLLUTION EFFECTS KW - QUANTITATIVE ANALYSIS KW - CARBON MONOXIDE KW - URBAN ATMOSPHERE KW - PARTICULATES KW - MORTALITY PATTERNS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forest+Ecology+and+Management&rft.atitle=Growth+and+stem+form+responses+of+plantation-grown+Acacia+melanoxylon+%28R.+Br.%29+to+form+pruning+and+nurse-crop+thinning&rft.au=Medhurst%2C+J+L%3BPinkard%2C+E+A%3BBeadle%2C+CL%3BWorledge%2C+D&rft.aulast=Medhurst&rft.aufirst=J&rft.date=2003-07-03&rft.volume=179&rft.issue=1-3&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Forest+Ecology+and+Management&rft.issn=03781127&rft_id=info:doi/10.1016%2FS0378-1127%2802%2900521-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NITROGEN DIOXIDE; SULFUR DIOXIDE; AIR POLLUTION EFFECTS; QUANTITATIVE ANALYSIS; CARBON MONOXIDE; MORTALITY PATTERNS; PARTICULATES; URBAN ATMOSPHERE ER - TY - JOUR T1 - Temporal Variability of Urinary Phthalate Metabolite Levels in Men of Reproductive Age AN - 14715747; 10672907 AB - The temporal variability in urinary phthalate metabolite levels was investigated in 11 men. Up to ten spot urine samples were collected during three cycles over a 92-d period. Substantial within-subject variability in urinary phthalate metabolite levels was found, but the sensitivity of a single spot urine sample to predict three-month average phthalate exposure was found to be moderate to high. However, the collection of additional urine samples one to three months apart improved the prediction of a subject's three-month average exposure. A single urine sample was more predictive for monoethyl phthalate than for mono-(2-ethylhexyl) phthalate. JF - Environmental Health Perspectives AU - Hauser, Russ AU - Meeker, John D AU - Park, Sohee AU - Silva, Manori J AU - Calafat, Antonia M Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1734 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOLOGICAL INDICATORS KW - PHTHALIC ACID ESTERS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14715747?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Temporal+Variability+of+Urinary+Phthalate+Metabolite+Levels+in+Men+of+Reproductive+Age&rft.au=Hauser%2C+Russ%3BMeeker%2C+John+D%3BPark%2C+Sohee%3BSilva%2C+Manori+J%3BCalafat%2C+Antonia+M&rft.aulast=Hauser&rft.aufirst=Russ&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1734&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 10 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOLOGICAL INDICATORS; PHTHALIC ACID ESTERS; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Synergistic Embryotoxicity of Polycyclic Aromatic Hydrocarbon Aryl Hydrocarbon Receptor Agonists with Cytochrome P4501A Inhibitors in Fundulus heterclitus AN - 14714209; 10672896 AB - While a strong, positive relationship has been found between the ability of PAHs to bind the aryl hydrocarbon receptor (AHR) and their induction of cytochrome P4501A (CYP1A), conclusions regarding the role of the AHR pathway and CYP1A activity in the toxicity of PAHs have been less clear. In this study, killifish Fundulus heteroclitus embryos were treated with three different AHR agonists and four CYP1A inhibitors that work by various mechanisms, and the embryos were analyzed for in ovo CYP1A activity and for deformities. A wide range of concentrations of AHR agonists were used to elicit a range of ethoxyresorufin O-deethylase inductions with and without inducing deformities. Results indicated that co-exposure to PAH-type AHR agonists and CYP1A inhibitors consistently enhanced embryotoxicity beyond levels predicted by an additive toxicity model. The inhibitors used in the study, which included PCB 126, benzo(a)pyrene, and beta -naphthoflavone, caused similar increases in PAH toxicity, although the inhibitors varied in structure and mechanism of inhibition. JF - Environmental Health Perspectives AU - Wassenberg, Deena M AU - Di Giulio, Richard T Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1658 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PHYSIOLOGICAL RESPONSES, FISH KW - PROTEIN SYNTHESIS KW - POLYCYCLIC AROMATIC HYDROCARBON KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14714209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Synergistic+Embryotoxicity+of+Polycyclic+Aromatic+Hydrocarbon+Aryl+Hydrocarbon+Receptor+Agonists+with+Cytochrome+P4501A+Inhibitors+in+Fundulus+heterclitus&rft.au=Wassenberg%2C+Deena+M%3BDi+Giulio%2C+Richard+T&rft.aulast=Wassenberg&rft.aufirst=Deena&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1658&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; PHYSIOLOGICAL RESPONSES, FISH; PROTEIN SYNTHESIS; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Epidemiology of Health Effects of Radiofrequency Exposure AN - 14713958; 10672908 JF - Environmental Health Perspectives AU - Ahlbom, Anders AU - Green, Adele AU - Kheifets, Leeka AU - Savitz, David AU - Swerdlow, Anthony Y1 - 2004/12// PY - 2004 DA - Dec 2004 SP - 1741 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 17 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PUBLIC HEALTH KW - ELECTROMAGNETIC FIELDS KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713958?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Epidemiology+of+Health+Effects+of+Radiofrequency+Exposure&rft.au=Ahlbom%2C+Anders%3BGreen%2C+Adele%3BKheifets%2C+Leeka%3BSavitz%2C+David%3BSwerdlow%2C+Anthony&rft.aulast=Ahlbom&rft.aufirst=Anders&rft.date=2004-12-01&rft.volume=112&rft.issue=17&rft.spage=1741&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PUBLIC HEALTH; ELECTROMAGNETIC FIELDS; LITERATURE SURVEYS ER - TY - CPAPER T1 - Characterization of clays used in the ceramic manufacturing industry by reflectance spectroscopy AN - 39906430; 3893996 AU - de Senna, JA AU - Fo, CRS Y1 - 2004/11/19/ PY - 2004 DA - 2004 Nov 19 KW - CPI, Conference Papers Index KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39906430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Characterization+of+clays+used+in+the+ceramic+manufacturing+industry+by+reflectance+spectroscopy&rft.au=de+Senna%2C+JA%3BFo%2C+CRS&rft.aulast=de+Senna&rft.aufirst=JA&rft.date=2004-11-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ICAM 2004, c/o Federal Inst. for Geosciences and Natural Resources, B4.15 Inorganic Geochemistry, Stilleweg 2, D-30655 Hannover, Germany; URL: www.icam2004.org N1 - Last updated - 2010-05-03 ER - TY - GEN T1 - Mexico's Counter-narcotics Efforts under Fox, December 2000 to October 2004 AN - 1679099229; MD01536 AB - Reviews projects and provides information on status of Mexican and U.S.-Mexico bilateral counternarcotics efforts after first four years of President Fox's administration. AU - United States. Library of Congress. Congressional Research Service AD - United States. Library of Congress. Congressional Research Service PY - 2004 SP - 16 KW - Arrest KW - Cocaine KW - Congressional oversight KW - Corruption KW - Crop eradication KW - Drug certification KW - Drug seizures KW - Drug traffic KW - Extradition KW - Heroin KW - Laundering of funds KW - Law enforcement cooperation KW - Marijuana KW - Methamphetamine KW - Operation Trifecta KW - Villanueva Madrid, Mario KW - Fox Quesada, Vicente KW - Bush, George W. KW - Villanueva Madrid, Mario KW - Fox Quesada, Vicente KW - Bush, George W. UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679099229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_md&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Mexico%27s+Counter-narcotics+Efforts+under+Fox%2C+December+2000+to+October+2004&rft.au=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aulast=United+States.+Library+of+Congress.+Congressional+Research+Service&rft.aufirst=&rft.date=2004-11-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ L2 - http://fpc.state.gov/c18183.htm. LA - English DB - Digital National Security Archive N1 - Name - Mexico-United States High-Level Contact Group for Drug Control; Mexico. Attorney General's Office; Mexico. Attorney General's Office. Federal Investigation Agency; United States. Department of State. Bureau of International Narcotics and Law Enforcement Affairs N1 - Analyte descriptor - NSA document type: Report; Location of original: Available [Online]: State Department, Bureau of Public Affairs Foreign Press Centers N1 - People - Bush, George W.; Fox Quesada, Vicente; Villanueva Madrid, Mario N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - Snoring in primary school children and domestic environment: a Perth school based study. AN - 67177921; 15527500 AB - The home is the predominant environment for exposure to many environmental irritants such as air pollutants and allergens. Exposure to common indoor irritants including volatile organic compounds, formaldehyde and nitrogen dioxide, may increase the risk of snoring for children. The aim of this study was to investigate domestic environmental factors associated with snoring in children. A school-based respiratory survey was administered during March and April of 2002. Nine hundred and ninety six children from four primary schools within the Perth metropolitan area were recruited for the study. A sub-group of 88 children aged 4-6 years were further selected from this sample for domestic air pollutant assessment. The prevalences of infrequent snoring and habitual snoring in primary school children were 24.9% and 15.2% respectively. Passive smoking was found to be a significant risk factor for habitual snoring (odds ratio (OR) = 1.77; 95% confidence interval (CI): 1.20-2.61), while having pets at home appeared to be protective against habitual snoring (OR = 0.58; 95% CI: 0.37-0.92). Domestic pollutant assessments showed that the prevalence of snoring was significantly associated with exposure to nitrogen dioxide during winter. Relative to the low exposure category ( 60 microg/m3) to NO2 were 2.5 (95% CI: 0.7-8.7) and 4.5 (95% CI: 1.4-14.3) respectively. The corresponding linear dose-response trend was also significant (P = 0.011). Snoring is common in primary school children. Domestic environments may play a significant role in the increased prevalence of snoring. Exposure to nitrogen dioxide in domestic environment is associated with snoring in children. JF - Respiratory research AU - Zhang, Guicheng AU - Spickett, Jeffery AU - Rumchev, Krassi AU - Lee, Andy H AU - Stick, Stephen AD - School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia. zhangg@exchange.curtin.edu.au Y1 - 2004/11/04/ PY - 2004 DA - 2004 Nov 04 SP - 19 VL - 5 KW - Air Pollutants KW - 0 KW - Tobacco Smoke Pollution KW - Index Medicus KW - Australia -- epidemiology KW - Risk Factors KW - Humans KW - Health Status KW - Surveys and Questionnaires KW - Child KW - Air Pollutants -- analysis KW - Schools -- statistics & numerical data KW - Male KW - Female KW - Comorbidity KW - Prevalence KW - Child, Preschool KW - Asthma -- epidemiology KW - Population KW - Snoring -- epidemiology KW - Risk Assessment -- methods KW - Air Pollution, Indoor -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67177921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Respiratory+research&rft.atitle=Snoring+in+primary+school+children+and+domestic+environment%3A+a+Perth+school+based+study.&rft.au=Zhang%2C+Guicheng%3BSpickett%2C+Jeffery%3BRumchev%2C+Krassi%3BLee%2C+Andy+H%3BStick%2C+Stephen&rft.aulast=Zhang&rft.aufirst=Guicheng&rft.date=2004-11-04&rft.volume=5&rft.issue=&rft.spage=19&rft.isbn=&rft.btitle=&rft.title=Respiratory+research&rft.issn=1465-993X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-03-14 N1 - Date created - 2004-12-13 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Arch Environ Health. 2001 Sep-Oct;56(5):433-8 [11777024] Pediatrics. 2002 Apr;109(4):e69 [11927742] Pediatrics. 2003 Mar;111(3):554-63 [12612236] Monaldi Arch Chest Dis. 2002 Jun-Aug;57(3-4):161-3 [12619373] Singapore Med J. 2002 Nov;43(11):554-6 [12683350] BMJ. 1999 Sep 25;319(7213):815-9 [10496824] Chest. 2003 May;123(5):1561-6 [12740274] Lancet. 2003 Jun 7;361(9373):1939-44 [12801737] Chest. 2003 Aug;124(2):587-93 [12907547] J Pediatr. 2003 Apr;142(4):377-82 [12712054] Chest. 2003 Nov;124(5):1709-15 [14605039] Sleep. 2004 Mar 15;27(2):274-8 [15124722] Thorax. 2004 Sep;59(9):746-51 [15333849] Am Ind Hyg Assoc J. 1976 OCT;37(10):570-7 [983946] Biochem Pharmacol. 1988 Apr 15;37(8):1497-507 [3358780] BMJ. 1989 Dec 16;299(6714):1491-4 [2514859] Am Rev Respir Dis. 1990 May;141(5 Pt 1):1119-26 [2339834] Chest. 1997 Jan;111(1):170-3 [8996012] Clin Exp Allergy. 1999 May;29(5):611-7 [10231320] Respir Med. 2001 May;95(5):423-9 [11392586] Math Biosci. 2001 Mar;170(1):79-90 [11259804] Arch Otolaryngol Head Neck Surg. 2000 Apr;126(4):481-6 [10772301] Chest. 2001 Dec;120(6):1930-5 [11742924] Pediatr Pulmonol. 2001 Sep;32(3):222-7 [11536452] Occup Environ Med. 2003 Nov;60(11):892-6 [14573722] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Female-biased sex allocation in peregrine falcons and other raptors AN - 754566174; 13413365 AB - The sex ratios of nestling Falconiformes in which males are smaller than females are often female biased, despite the apparent costs involved in producing very large female offspring. In Australian peregrine falcons, Falco peregrinus, this bias is most pronounced in broods produced early in the season, and the first eggs to be laid are most likely to produce females. Females that lay early are most likely to be successful breeders. Very large chicks tend to occur in female-biased broods. Collectively, these data suggest that females likely to produce large offspring produce daughters. A modified version of the Trivers/Willard hypothesis is suggested to account for this pattern. JF - Behavioral Ecology and Sociobiology AU - Olsent, Penny D AU - Cockburn, Andrew AD - Department of Zoology, Australian National University, GPO Box 4, ACT 2601, Canberra City, Australia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 417 EP - 423 PB - Springer-Verlag, Heidelberger Platz 3 Berlin 14197 Germany VL - 28 IS - 6 SN - 0340-5443, 0340-5443 KW - Ecology Abstracts; Animal Behavior Abstracts KW - Falco peregrinus KW - Data processing KW - Sex ratio KW - Falconiformes KW - Progeny KW - Eggs KW - Sex KW - Y 25040:Behavioral Ecology KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754566174?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Behavioral+Ecology+and+Sociobiology&rft.atitle=Female-biased+sex+allocation+in+peregrine+falcons+and+other+raptors&rft.au=Olsent%2C+Penny+D%3BCockburn%2C+Andrew&rft.aulast=Olsent&rft.aufirst=Penny&rft.date=2004-11-01&rft.volume=28&rft.issue=6&rft.spage=417&rft.isbn=&rft.btitle=&rft.title=Behavioral+Ecology+and+Sociobiology&rft.issn=03405443&rft_id=info:doi/10.1007%2FBF00164123 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Data processing; Sex ratio; Progeny; Eggs; Sex; Falco peregrinus; Falconiformes DO - http://dx.doi.org/10.1007/BF00164123 ER - TY - JOUR T1 - Foreign relations of the United States, 1952-1954: Guatemala AN - 37987154; 2865220 JF - Diplomatic history AU - Rabe, Stephen G AU - Rabe, Stephen G Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 785 EP - 790 PB - US Government Printing Office VL - 28 IS - 5 SN - 0145-2096, 0145-2096 KW - Political Science KW - International relations KW - Guatemala KW - History of international relations KW - U.S.A. KW - Foreign relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37987154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Diplomatic+history&rft.atitle=Foreign+relations+of+the+United+States%2C+1952-1954%3A+Guatemala&rft.au=Rabe%2C+Stephen+G&rft.aulast=Rabe&rft.aufirst=Stephen&rft.date=2004-11-01&rft.volume=28&rft.issue=5&rft.spage=785&rft.isbn=&rft.btitle=&rft.title=Diplomatic+history&rft.issn=01452096&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 6784; 5906 6784; 5205; 433 293 14; 156 84 14 ER - TY - JOUR T1 - Using Decision Forest to Classify Prostate Cancer Samples on the Basis of SELDI-TOF MS Data: Assessing Chance Correlation and Prediction Confidence AN - 21430966; 12425813 AB - Class prediction using "omics" data is playing an increasing role in toxicogenomics, diagnosis/prognosis, and risk assessment. These data are usually noisy and represented by relatively few samples and a very large number of predictor variables (e.g., genes of DNA microarray data or m/z peaks of mass spectrometry data). These characteristics manifest the importance of assessing potential random correlation and overfitting of noise for a classification model based on omics data. We present a novel classification method, decision forest (DF), for class prediction using omics data. DF combines the results of multiple heterogeneous but comparable decision tree (DT) models to produce a consensus prediction. The method is less prone to overfitting of noise and chance correlation. A DF model was developed to predict presence of prostate cancer using a proteomic data set generated from surface-enhanced laser deposition/ionization time-of-flight mass spectrometry (SELDI-TOF MS). The degree of chance correlation and prediction confidence of the model was rigorously assessed by extensive cross-validation and randomization testing. Comparison of model prediction with imposed random correlation demonstrated biologic relevance of the model and the reduction of overfitting in DF. Furthermore, two confidence levels (high and low confidences) were assigned to each prediction, where most misclassifications were associated with the low-confidence region. For the high-confidence prediction, the model achieved 99.2% sensitivity and 98.2% specificity. The model also identified a list of significant peaks that could be useful for biomarker identification. DF should be equally applicable to other omics data such as gene expression data or metabolomic data. The DF algorithm is available upon request. JF - Environmental Health Perspectives AU - Tong, Weida AU - Xie, Qian AU - Hong, Huixiao AU - Fang, Hong Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1622 EP - 1627 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Bioindicators KW - Risk assessment KW - Sensitivity KW - classification KW - Noise levels KW - Forests KW - Mass spectrometry KW - Lasers KW - prostate cancer KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21430966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+Decision+Forest+to+Classify+Prostate+Cancer+Samples+on+the+Basis+of+SELDI-TOF+MS+Data%3A+Assessing+Chance+Correlation+and+Prediction+Confidence&rft.au=Tong%2C+Weida%3BXie%2C+Qian%3BHong%2C+Huixiao%3BFang%2C+Hong&rft.aulast=Tong&rft.aufirst=Weida&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1622&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Risk assessment; Bioindicators; Sensitivity; classification; Noise levels; Mass spectrometry; Forests; Lasers; prostate cancer ER - TY - JOUR T1 - Lung Cancer in Railroad Workers Exposed to Diesel Exhaust AN - 21430214; 12429301 AB - Diesel exhaust has been suspected to be a lung carcinogen. The assessment of this lung cancer risk has been limited by lack of studies of exposed workers followed for many years. In this study, we assessed lung cancer mortality in 54,973 U.S. railroad workers between 1959 and 1996 (38 years). By 1959, the U.S. railroad industry had largely converted from coal-fired to diesel-powered locomotives. We obtained work histories from the U.S. Railroad Retirement Board, and ascertained mortality using Railroad Retirement Board, Social Security, and Health Care Financing Administration records. Cause of death was obtained from the National Death Index and death certificates. There were 43,593 total deaths including 4,351 lung cancer deaths. Adjusting for a healthy worker survivor effect and age, railroad workers in jobs associated with operating trains had a relative risk of lung cancer mortality of 1.40 (95% confidence interval, 1.30-1.51). Lung cancer mortality did not increase with increasing years of work in these jobs. Lung cancer mortality was elevated in jobs associated with work on trains powered by diesel locomotives. Although a contribution from exposure to coal combustion products before 1959 cannot be excluded, these results suggest that exposure to diesel exhaust contributed to lung cancer mortality in this cohort. Key words: diesel exhaust, lung cancer, occupational exposure. JF - Environmental Health Perspectives AU - Garshick, Eric AU - Laden, Francine AU - Hart, Jaime E AU - Rosner, Bernard Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1539 EP - 1543 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Mortality KW - USA KW - locomotives KW - Combustion products KW - Railroads KW - Diesel engines KW - Cancer KW - Occupational exposure KW - Lung cancer KW - Exhaust emissions KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21430214?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lung+Cancer+in+Railroad+Workers+Exposed+to+Diesel+Exhaust&rft.au=Garshick%2C+Eric%3BLaden%2C+Francine%3BHart%2C+Jaime+E%3BRosner%2C+Bernard&rft.aulast=Garshick&rft.aufirst=Eric&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1539&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Mortality; locomotives; Combustion products; Railroads; Diesel engines; Occupational exposure; Cancer; Exhaust emissions; Lung cancer; USA ER - TY - JOUR T1 - The Relationship between Housing and Health: Children at Risk AN - 21423192; 12429288 AB - In November 2002, the National Center for Healthy Housing convened a 2-day workshop to review the state of knowledge in the field of healthy housing. The workshop, supported with funds from the U.S. Centers for Disease Control and Prevention's National Center for Injury Prevention and Control and National Center for Environmental Health, was unique in that it focused solely on the effect of housing on children's health and the translation of research findings into practical activities in home construction, rehabilitation, and maintenance. Participants included experts and practitioners representing the health, housing, and environmental arenas. Presentations by subject-matter experts covered four key areas: asthma, neurotoxicants, injury, and translational research. Panel discussions followed the presentations, which generated robust dialogue on potential future research opportunities and overall policy gaps. Lack of consensus on standard measurements, incomplete understanding about the interaction of home hazards, inadequate research on the effectiveness of interventions, and insufficient political support limit current efforts to achieve healthy housing. However, change is forthcoming and achievable. Key words: asthma, childhood exposure, environmental toxicants, healthy housing, lead poisoning. JF - Environmental Health Perspectives AU - Breysse, Patrick AU - Farr, Nick AU - Galke, Warren AU - Lanphear, Bruce Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1583 EP - 1588 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - USA KW - Housing KW - Injuries KW - Toxicants KW - Politics KW - prevention KW - Asthma KW - Respiratory diseases KW - Children KW - Lead KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423192?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+between+Housing+and+Health%3A+Children+at+Risk&rft.au=Breysse%2C+Patrick%3BFarr%2C+Nick%3BGalke%2C+Warren%3BLanphear%2C+Bruce&rft.aulast=Breysse&rft.aufirst=Patrick&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1583&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Toxicants; Injuries; Housing; Politics; prevention; Asthma; Respiratory diseases; Children; Lead; USA ER - TY - JOUR T1 - Subchronic Exposure to TCDD, PeCDF, PCB126, and PCB153: Effect on Hepatic Gene Expression AN - 21422649; 12425814 AB - We employed DNA microarray to identify unique hepatic gene expression patterns associated with subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other halogenated aromatic hydrocarbons (HAHs). Female Harlan Sprague-Dawley rats were exposed for 13 weeks to toxicologically equivalent doses of four different HAHs based on the toxic equivalency factor of each chemical: TCDD (100 ng/kg/day), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF; 200 ng/kg/day), 3,3',4,4',5-pentachlorobiphenyl (PCB126; 1,000 ng/kg/day), or 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153; 1,000 microg/kg/day). Global gene expression profiles for each exposure, which account for 8,799 gene probe sets contained on Affymetrix RGU34A GeneChips, were compared by principal components analysis. The aryl hydrocarbon receptor (AhR) ligands TCDD, PeCDF, and PCB126 produced very similar global gene expression profiles that were unique from the nonAhR ligand PCB153, underscoring the extensive impact of AhR activation and/or the resulting hepatic injury on global gene expression in female rat liver. Many genes were co-expressed during the 13-week TCDD, PeCDF, or PCB126 exposures, including classical AhR-regulated genes and some genes not previously characterized as being AhR regulated, such as carcinoembryonic-cell adhesion molecule 4 (C-CAM4) and adenylate cyclase-associated protein 2 (CAP2). Real-time reverse-transcriptase polymerase chain reaction confirmed the increased expression of these genes in TCDD-, PeCDF-, and PCB126-exposed rats as well as the up- or down-regulation of several other novel dioxin-responsive genes. In summary, DNA microarray successfully identified dioxin-responsive genes expressed after exposure to AhR ligands (TCDD, PeCDF, PCB126) but not after exposure to the non-AhR ligand PCB153. Together, these findings may help to elucidate some of the fundamental features of dioxin toxicity and may further clarify the biologic role of the AhR signaling pathway. JF - Environmental Health Perspectives AU - Vezina, Chad M AU - Walker, Nigel J AU - Olson, James R Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1636 EP - 1644 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Rats KW - principal components analysis KW - DNA KW - Liver KW - TCDD KW - Proteins KW - Toxicity KW - aromatic hydrocarbons KW - Dioxins KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21422649?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Subchronic+Exposure+to+TCDD%2C+PeCDF%2C+PCB126%2C+and+PCB153%3A+Effect+on+Hepatic+Gene+Expression&rft.au=Vezina%2C+Chad+M%3BWalker%2C+Nigel+J%3BOlson%2C+James+R&rft.aulast=Vezina&rft.aufirst=Chad&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1636&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Rats; principal components analysis; Liver; DNA; Proteins; TCDD; Toxicity; Dioxins; aromatic hydrocarbons ER - TY - JOUR T1 - Lead Sources in Human Diet in Greenland AN - 21422565; 12429305 AB - Although blood lead levels have declined in Greenland, they are still elevated despite the fact that lead levels in the Greenland environment are very low. Fragments of lead shot in game birds have been suggested as an important source of dietary exposure, and meals of sea birds, particularly eider, contain high concentrations of lead. In a cross-sectional population survey in Greenland in 1993-1994, blood lead adjusted for age and sex was found to be associated with the reported consumption of sea birds. Participants reporting less than weekly intake of sea birds had blood lead concentrations of approximately 75 microg/L, whereas those who reported eating sea birds several times a week had concentrations of approximately 110 microg/L, and those who reported daily intake had concentrations of 170 microg/L (p = 0.01). Blood lead was not associated with dietary exposure to other local or imported food items. JF - Environmental Health Perspectives AU - Bjerregaard, Peter AU - Johansen, Poul AU - Mulvad, Gert AU - Pedersen, Henning Sloth AU - Hansen, Jens C Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1496 EP - 1498 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - Aves KW - Diets KW - Biological surveys KW - Marine KW - Age KW - Marine birds KW - Population structure KW - Lead KW - AN, Greenland KW - Blood levels KW - Q5 08504:Effects on organisms KW - ENA 12:Oceans & Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21422565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lead+Sources+in+Human+Diet+in+Greenland&rft.au=Bjerregaard%2C+Peter%3BJohansen%2C+Poul%3BMulvad%2C+Gert%3BPedersen%2C+Henning+Sloth%3BHansen%2C+Jens+C&rft.aulast=Bjerregaard&rft.aufirst=Peter&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1496&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Biological surveys; Diets; Marine birds; Population structure; Aves; Age; Lead; Blood levels; AN, Greenland; Marine ER - TY - JOUR T1 - Systems Biology: The Big Picture AN - 21418266; 12425811 AB - Systems biology-a field that draws from mathematics, engineering, nanotechnology, and computer science--is poised to take biology to a new level as it offers understanding of the wealth of data flowing from the "omics" fields. Systems biology looks at the data produced by genomics, proteomics, and metabolomics studies, and visualizes how an organism's biological processes intertwine to produce a whole greater than the sum of its parts. A working model of an entire biological system could impart enormous power for learning how environmental exposures result in disease. Today, practitioners are working to define their field--for example, its terminology and analytical tools--in an attempt to make their efforts pay off. JF - Environmental Health Perspectives AU - Spivey, Angela Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A938 EP - A943 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - nanotechnology KW - ENA 06:Food & Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21418266?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Systems+Biology%3A+The+Big+Picture&rft.au=Spivey%2C+Angela&rft.aulast=Spivey&rft.aufirst=Angela&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A938&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - nanotechnology ER - TY - JOUR T1 - In Vivo Imaging of Activated Estrogen Receptors in Utero by Estrogens and Bisphenol A AN - 21417205; 12429292 AB - Environmental estrogens are of particular concern when exposure occurs during embryonic development. Although there are good models to study estrogenic activity of chemicals in adult animals, developmental exposure is much more difficult to test. The weak estrogenic activity of the environmental estrogen bisphenol A (BPA) in embryos is controversial. We have recently generated transgenic mice that carry a reporter construct with estrogen-responsive elements coupled to luciferase. We show that, using this in vivo model in combination with the IVIS imaging system, activation of estrogen receptors (ERs) by maternally applied BPA and other estrogens can be detected in living embryos in utero. Eight hours after exposure to 1 mg/kg BPA, ER transactivation could be significantly induced in the embryos. This was more potent than would be estimated from in vitro assays, although its intrinsic activity is still lower than that of diethylstilbestrol and 17beta-estradiol dipropionate. On the basis of these results, we conclude that the estrogenic potency of BPA estimated using in vitro assays might underestimate its estrogenic potential in embryos. JF - Environmental Health Perspectives AU - Lemmen, Josephine G AU - Arends, Roel J AU - van der Saag, Paul T AU - van der Burg, Bart Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1544 EP - 1549 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Chemicals KW - bisphenol A KW - Embryos KW - Mice KW - estrogens KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21417205?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=In+Vivo+Imaging+of+Activated+Estrogen+Receptors+in+Utero+by+Estrogens+and+Bisphenol+A&rft.au=Lemmen%2C+Josephine+G%3BArends%2C+Roel+J%3Bvan+der+Saag%2C+Paul+T%3Bvan+der+Burg%2C+Bart&rft.aulast=Lemmen&rft.aufirst=Josephine&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1544&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Chemicals; bisphenol A; Mice; Embryos; estrogens ER - TY - JOUR T1 - Mass Spectrometry Group Has Mass Appeal AN - 21407171; 12425815 AB - The field of proteomics seeks to define, on a global scale, the levels, activities, regulation, and interaction of proteins in a biological sample. Proteomics is analogous to transcriptomics--the global analysis of mRNA transcripts that arise from the expression of genes in the genome--although the former is considerably more complicated. Whereas the human genome comprises approximately 30,000 genes, there are likely over 100,000 unique proteins in the human proteome due to the multiple ways each gene can be transcribed and translated into proteins by cellular machinery. JF - Environmental Health Perspectives AU - Eubanks, Mary Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A936 EP - A937 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Machinery KW - Proteins KW - Mass spectrometry KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21407171?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Mass+Spectrometry+Group+Has+Mass+Appeal&rft.au=Eubanks%2C+Mary&rft.aulast=Eubanks&rft.aufirst=Mary&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A936&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Machinery; Mass spectrometry; Proteins ER - TY - JOUR T1 - Listing Occupational Carcinogens AN - 21406583; 12429306 AB - The occupational environment has been a most fruitful one for investigating the etiology of human cancer. Many recognized human carcinogens are occupational carcinogens. There is a large volume of epidemiologic and experimental data concerning cancer risks in different work environments. It is important to synthesize this information for both scientific and public health purposes. Various organizations and individuals have published lists of occupational carcinogens. However, such lists have been limited by unclear criteria for which recognized carcinogens should be considered occupational carcinogens, and by inconsistent and incomplete information on the occupations and industries in which the carcinogenic substances may be found and on their target sites of cancer. Based largely on the evaluations published by the International Agency for Research on Cancer, and augmented with additional information, the present article represents an attempt to summarize, in tabular form, current knowledge on occupational carcinogens, the occupations and industries in which they are found, and their target organs. We have considered 28 agents as definite occupational carcinogens, 27 agents as probable occupational carcinogens, and 113 agents as possible occupational carcinogens. These tables should be useful for regulatory or preventive purposes and for scientific purposes in research priority setting and in understanding carcinogenesis. JF - Environmental Health Perspectives AU - Siemiatycki, Jack AU - Richardson, Lesley AU - Straif, Kurt AU - Latreille, Benoit Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1447 EP - 1459 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Etiology KW - Carcinogenicity KW - Carcinogenesis KW - Carcinogens KW - Organs KW - Cancer KW - Public health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406583?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Listing+Occupational+Carcinogens&rft.au=Siemiatycki%2C+Jack%3BRichardson%2C+Lesley%3BStraif%2C+Kurt%3BLatreille%2C+Benoit&rft.aulast=Siemiatycki&rft.aufirst=Jack&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1447&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Etiology; Carcinogenicity; Carcinogenesis; Carcinogens; Organs; Cancer; Public health ER - TY - JOUR T1 - Production of Androgens by Microbial Transformation of Progesterone in Vitro: A Model for Androgen Production in Rivers Receiving Paper Mill Effluent AN - 21405990; 12429303 AB - We have previously documented the presence of progesterone and androstenedione in the water column and bottom sediments of the Fenholloway River, Taylor County, Florida. This river receives paper mill effluent and contains masculinized female mosquitofish. We hypothesized that plant sterols (e.g., ss-sitosterol) derived from the pulping of pine trees are transformed by bacteria into progesterone and subsequently into 17alpha-hydroxyprogesterone, androstenedione, and other androgens. In this study, we demonstrate that these same androgens can be produced in vitro from the bacterium Mycobacterium smegmatis. In a second part to this study, we reextracted and reanalyzed the sediment from the Fenholloway River and verified the presence of androstadienedione, a delta1 steroid with androgen activity. JF - Environmental Health Perspectives AU - Jenkins, Ronald L AU - Wilson, Elizabeth M AU - Angus, Robert A AU - Howell, W Mike Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1508 EP - 1511 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Rivers KW - USA, Florida, Fenholloway R. KW - paper mills KW - USA, Florida KW - Trees KW - water column KW - steroids KW - Effluents KW - Sediments KW - Mycobacterium smegmatis KW - ENA 19:Water Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21405990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Production+of+Androgens+by+Microbial+Transformation+of+Progesterone+in+Vitro%3A+A+Model+for+Androgen+Production+in+Rivers+Receiving+Paper+Mill+Effluent&rft.au=Jenkins%2C+Ronald+L%3BWilson%2C+Elizabeth+M%3BAngus%2C+Robert+A%3BHowell%2C+W+Mike&rft.aulast=Jenkins&rft.aufirst=Ronald&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1508&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Rivers; paper mills; Trees; water column; steroids; Effluents; Sediments; Mycobacterium smegmatis; USA, Florida, Fenholloway R.; USA, Florida ER - TY - JOUR T1 - The TAO-Gen Algorithm for Identifying Gene Interaction Networks with Application to SOS Repair in E. coli AN - 21379205; 12425816 AB - One major unresolved issue in the analysis of gene expression data is the identification and quantification of gene regulatory networks. Several methods have been proposed for identifying gene regulatory networks, but these methods predominantly focus on the use of multiple pairwise comparisons to identify the network structure. In this article, we describe a method for analyzing gene expression data to determine a regulatory structure consistent with an observed set of expression profiles. Unlike other methods this method goes beyond pairwise evaluations by using likelihood-based statistical methods to obtain the network that is most consistent with the complete data set. The proposed algorithm performs accurately for moderate-sized networks with most errors being minor additions of linkages. However, the analysis also indicates that sample sizes may need to be increased to uniquely identify even moderate-sized networks. The method is used to evaluate interactions between genes in the SOS signaling pathway in Escherichia coli using gene expression data where each gene in the network is over-expressed using plasmids inserts. JF - Environmental Health Perspectives AU - Yamanaka, Takeharu AU - Toyoshiba, Hiroyoshi AU - Sone, Hideko AU - Parham, Frederick M AU - Portier, Christopher J Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1614 EP - 1621 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Genetics KW - Escherichia coli KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21379205?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+TAO-Gen+Algorithm+for+Identifying+Gene+Interaction+Networks+with+Application+to+SOS+Repair+in+E.+coli&rft.au=Yamanaka%2C+Takeharu%3BToyoshiba%2C+Hiroyoshi%3BSone%2C+Hideko%3BParham%2C+Frederick+M%3BPortier%2C+Christopher+J&rft.aulast=Yamanaka&rft.aufirst=Takeharu&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1614&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Genetics; Escherichia coli ER - TY - JOUR T1 - Phenotypic Anchoring of Gene Expression Changes during Estrogen-Induced Uterine Growth AN - 21379172; 12425809 AB - A major challenge in the emerging field of toxicogenomics is to define the relationships between chemically induced changes in gene expression and alterations in conventional toxicologic parameters such as clinical chemistry and histopathology. We have explored these relationships in detail using the rodent uterotrophic assay as a model system. Gene expression levels, uterine weights, and histologic parameters were analyzed 1, 2, 4, 8, 24, 48, and 72 hr after exposure to the reference physiologic estrogen 17 beta-estradiol (E2). A multistep analysis method, involving unsupervised hierarchical clustering followed by supervised gene ontology-driven clustering, was used to define the transcriptional program associated with E2-induced uterine growth and to identify groups of genes that may drive specific histologic changes in the uterus. This revealed that uterine growth and maturation are preceded and accompanied by a complex, multistage molecular program. The program begins with the induction of genes involved in transcriptional regulation and signal transduction and is followed, sequentially, by the regulation of genes involved in protein biosynthesis, cell proliferation, and epithelial cell differentiation. Furthermore, we have identified genes with common molecular functions that may drive fluid uptake, coordinated cell division, and remodeling of luminal epithelial cells. These data define the mechanism by which an estrogen induces organ growth and tissue maturation, and demonstrate that comparison of temporal changes in gene expression and conventional toxicology end points can facilitate the phenotypic anchoring of toxicogenomic data. JF - Environmental Health Perspectives AU - Moggs, Jonathan G AU - Tinwell, Helen AU - Spurway, Tracey AU - Chang, Hur-Song Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1589 EP - 1606 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Biosynthesis KW - Growth KW - Histopathology KW - Proteins KW - cell differentiation KW - Organs KW - rodents KW - Toxicology KW - estrogens KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21379172?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Phenotypic+Anchoring+of+Gene+Expression+Changes+during+Estrogen-Induced+Uterine+Growth&rft.au=Moggs%2C+Jonathan+G%3BTinwell%2C+Helen%3BSpurway%2C+Tracey%3BChang%2C+Hur-Song&rft.aulast=Moggs&rft.aufirst=Jonathan&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1589&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Biosynthesis; Growth; Proteins; Histopathology; cell differentiation; Organs; Toxicology; rodents; estrogens ER - TY - JOUR T1 - Renal Toxicogenomic Response to Chronic Uranyl Nitrate Insult in Mice AN - 21372690; 12425810 AB - Although the nephrotoxicity of uranium has been established through numerous animal studies, relatively little is known about the effects of long-term environmental uranium exposure. Using a combination of conventional biochemical studies and serial analysis of gene expression (SAGE), we examined the renal responses to uranyl nitrate (UN) chronic exposure. Renal uranium levels were significantly increased 4 months after ingestion of uranium in drinking water. Creatinine levels in serum were slightly but significantly increased compared with those in controls. Although no further significant differences in other parameters were noted, substantial molecular changes were observed in toxicogenomic profiles. UN induced dramatic alterations in expression levels of more than 200 genes, mainly up-regulated, including oxidative-response-related genes, genes encoding for cellular metabolism, ribosomal proteins, signal transduction, and solute transporters. Seven differentially expressed transcripts were confirmed by real-time quantitative polymerase chain reaction. In addition, significantly increased peroxide levels support the implication of oxidative stress in UN toxicant response. This report highlights the potential of SAGE for the discovery of novel toxicant-induced gene expression alterations. Here, we present, for the first time, a comprehensive view of renal molecular events after uranium long-term exposure. JF - Environmental Health Perspectives AU - Taulan, Magali AU - Paquet, Francois AU - Maubert, Christophe AU - Delissen, Olivia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1628 EP - 1635 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Nitrates KW - Biochemistry KW - Toxicants KW - Uranium KW - Proteins KW - Drinking water KW - Ingestion KW - Metabolism KW - oxidative stress KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21372690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Renal+Toxicogenomic+Response+to+Chronic+Uranyl+Nitrate+Insult+in+Mice&rft.au=Taulan%2C+Magali%3BPaquet%2C+Francois%3BMaubert%2C+Christophe%3BDelissen%2C+Olivia&rft.aulast=Taulan&rft.aufirst=Magali&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1628&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Toxicants; Biochemistry; Nitrates; Uranium; Proteins; Ingestion; Drinking water; oxidative stress; Metabolism ER - TY - JOUR T1 - Organochlorine Exposure and Colorectal Cancer Risk AN - 21371556; 12429297 AB - Organochlorine compounds have been linked to increased risk of several cancers. Despite reductions in their use and fugitive release, they remain one of the most important groups of persistent pollutants to which humans are exposed, primarily through dietary intake. We designed a case-control study to assess the risk of colorectal cancer with exposure to these chemicals, and their potential interactions with genetic alterations in the tumors. A subsample of cases (n = 132) and hospital controls (n = 76) was selected from a larger case-control study in Barcelona, Catalonia, Spain. We measured concentrations in serum of several organochlorines by gas chromatography. We assessed point mutations in K-ras and p53 genes in tissue samples by polymerase chain reaction/single-strand conformation polymorphism and assessed expression of p53 protein by immunohistochemical methods. An elevated risk of colorectal cancer was associated with higher serum concentrations of mono-ortho polychlorinated biphenyl (PCB) congeners 28 and 118. The odds ratio for these mono-ortho PCBs for middle and higher tertile were, respectively, 1.82 [95% confidence interval (CI), 0.90-3.70] and 2.94 (95% CI, 1.39-6.20). Alpha-hexachlorocyclohexane, hexachlorobenzene, and p,p'-DDE (4,4'-dichlorodiphenyltrichloroethene) showed nonsignificant increases in risk. Risk associated with mono-ortho PCBs was slightly higher for tumors with mutations in the p53 gene but was not modified by mutations in K-ras. Mono-ortho PCBs were further associated with transversion-type mutations in both genes. These results generate the hypothesis that exposure to mono-ortho PCBs contributes to human colorectal cancer development. The trend and magnitude of the association, as well as the observation of a molecular fingerprint in tumors, raise the possibility that this finding may be causal. JF - Environmental Health Perspectives AU - Howsam, Mike AU - Grimalt, Joan O AU - Guino, Elisabet AU - Navarro, Matilde Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1460 EP - 1466 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Chemicals KW - Diets KW - Organochlorine compounds KW - colorectal carcinoma KW - tumors KW - Spain, Catalonia KW - Spain, Cataluna, Barcelona KW - PCB compounds KW - Mutation KW - Cancer KW - Hospitals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21371556?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Pre-+and+Postnatal+Exposure+to+Polychlorinated+Biphenyls%3A+Lessons+from+the+Inuit+Cohort+Study&rft.au=Ayotte%2C+Pierre%3BMuckle%2C+Gina%3BJacobson%2C+Joseph+L%3BJacobson%2C+Sandra+W%3BDewailly%2C+Eric&rft.aulast=Ayotte&rft.aufirst=Pierre&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1253&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Diets; Chemicals; Organochlorine compounds; colorectal carcinoma; tumors; Mutation; PCB compounds; Cancer; Hospitals; Spain, Catalonia; Spain, Cataluna, Barcelona ER - TY - JOUR T1 - Assessing Ozone-Related Health Impacts under a Changing Climate AN - 21370890; 12429290 AB - Climate change may increase the frequency and intensity of ozone episodes in future summers in the United States. However, only recently have models become available that can assess the impact of climate change on O3 concentrations and health effects at regional and local scales that are relevant to adaptive planning. We developed and applied an integrated modeling framework to assess potential O3-related health impacts in future decades under a changing climate. The National Aeronautics and Space Administration-Goddard Institute for Space Studies global climate model at 4 degrees x 5 degrees resolution was linked to the Penn State/National Center for Atmospheric Research Mesoscale Model 5 and the Community Multiscale Air Quality atmospheric chemistry model at 36 km horizontal grid resolution to simulate hourly regional meteorology and O3 in five summers of the 2050s decade across the 31-county New York metropolitan region. We assessed changes in O3-related impacts on summer mortality resulting from climate change alone and with climate change superimposed on changes in O3 precursor emissions and population growth. Considering climate change alone, there was a median 4.5% increase in O3-related acute mortality across the 31 counties. Incorporating O3 precursor emission increases along with climate change yielded similar results. When population growth was factored into the projections, absolute impacts increased substantially. Counties with the highest percent increases in projected O3 mortality spread beyond the urban core into less densely populated suburban counties. This modeling framework provides a potentially useful new tool for assessing the health risks of climate change. JF - Environmental Health Perspectives AU - Knowlton, Kim AU - Rosenthal, Joyce E AU - Hogrefe, Christian AU - Lynn, Barry Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1557 EP - 1563 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Mortality KW - population growth KW - Climatic changes KW - Emissions KW - Population density KW - summer KW - Air quality KW - metropolitan areas KW - USA, New York KW - Ozone KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21370890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessing+Ozone-Related+Health+Impacts+under+a+Changing+Climate&rft.au=Knowlton%2C+Kim%3BRosenthal%2C+Joyce+E%3BHogrefe%2C+Christian%3BLynn%2C+Barry&rft.aulast=Knowlton&rft.aufirst=Kim&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1557&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Mortality; population growth; Climatic changes; Population density; Emissions; summer; Air quality; metropolitan areas; Ozone; USA, New York ER - TY - JOUR T1 - 112-16, 2004: toxicogenomics forum. AN - 21368839; 12421270 AB - Articles: * The Year of the Rat * Getting to the Core of Antimicrobialse * Tackling Innate Immunity * Cellular Jigsaw Puzzles * txgNet: Y.F. Leung's Functional Genomics. JF - Environmental Health Perspectives AU - E, Hood AU - E, Susman AU - C, Potera AU - R, Dahl AU - EE, Dooley Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A930 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts; Environmental Engineering Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21368839?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=112-16%2C+2004%3A+toxicogenomics+forum.&rft.au=E%2C+Hood%3BE%2C+Susman%3BC%2C+Potera%3BR%2C+Dahl%3BEE%2C+Dooley&rft.aulast=E&rft.aufirst=Hood&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A930&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - EHP 112-16, 2004: Toxicogenomics Science Selections - Template for Toxicants: Gene Expression Varies by Cell Type, How E2 Induces Uterine Effects: Transcription Coordinates Cascade. AN - 21361971; 12421269 AB - Toxicogenomics Science Selections - Template for Toxicants: Gene Expression Varies by Cell Type, How E2 Induces Uterine Effects: Transcription Coordinates Cascade. JF - Environmental Health Perspectives AU - JR, Barrett Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - A944 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Toxicants KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21361971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=EHP+112-16%2C+2004%3A+Toxicogenomics+Science+Selections+-+Template+for+Toxicants%3A+Gene+Expression+Varies+by+Cell+Type%2C+How+E2+Induces+Uterine+Effects%3A+Transcription+Coordinates+Cascade.&rft.au=JR%2C+Barrett&rft.aulast=JR&rft.aufirst=Barrett&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=A944&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Toxicants ER - TY - JOUR T1 - Induced innovations and climate change policy AN - 20523386; 6192952 AB - With the recent progress in Bonn and Marrakech on the details required for implementing the Kyoto Protocol, entry into force in 2003 is now a possibility. This paper assesses the potential macroeconomic impacts of the Kyoto Protocol, given the recent negotiated developments. In addition, given the recent attempts in the literature to model endogenous technical change in general equilibrium models, a new methodology for incorporating the induced innovations hypothesis into a general equilibrium model is described and implemented. In line with previous work, it is found that incorporation of the hypothesis reduces abatement costs. JF - Energy Economics AU - Jakeman, G AU - Hanslow, K AU - Hinchy, M AU - Fisher, B S AU - Woffenden, K AD - Australian Bureau of Agricultural and Resource Economics, G.P.O. Box 1563, Canberra, ACT 2601, Australia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 937 EP - 960 VL - 26 IS - 6 SN - 0140-9883, 0140-9883 KW - Pollution Abstracts; Sustainability Science Abstracts KW - International cooperation KW - Economics KW - Climatic changes KW - Air pollution control KW - Emission control KW - Greenhouse gases KW - Kyoto Protocol KW - International agreements KW - P 9000:ENVIRONMENTAL ACTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20523386?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Energy+Economics&rft.atitle=Induced+innovations+and+climate+change+policy&rft.au=Jakeman%2C+G%3BHanslow%2C+K%3BHinchy%2C+M%3BFisher%2C+B+S%3BWoffenden%2C+K&rft.aulast=Jakeman&rft.aufirst=G&rft.date=2004-11-01&rft.volume=26&rft.issue=6&rft.spage=937&rft.isbn=&rft.btitle=&rft.title=Energy+Economics&rft.issn=01409883&rft_id=info:doi/10.1016%2Fj.eneco.2004.09.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-04-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - International cooperation; Climatic changes; Economics; Emission control; Air pollution control; Greenhouse gases; International agreements; Kyoto Protocol DO - http://dx.doi.org/10.1016/j.eneco.2004.09.002 ER - TY - JOUR T1 - Annual Scientific Meeting of ASCEPT 2003: ENZYMATIC BIOREMEDIATION: FROM ENZYME DISCOVERY TO APPLICATIONS AN - 19431572; 6229407 AB - 1. Enzymatic bioremediation is potentially a rapid method of removing environmental pesticide residues. Applications include the treatment of residues resulting from agricultural production and processing industries, such as the treatment of irrigation waters, surface-contaminated fruit and vegetables and spent dip liquors. 2. A specific application for some organophosphate-degrading enzymes involves detoxification of nerve agent stockpiles. Effective and affordable remediation requires highly specialized enzymes, so protein engineering techniques are being used to improve properties of various source enzymes to enhance catalytic rates, stability and substrate range. 3. Trials with an optimized organophosphate-degrading enzyme have shown the feasibility of such technology in various applications. 4. The enzymes developed for environmental remediation for specific pesticide classes also have applications as antidotes for high-dose pesticide poisonings and as prophylaxis for people at risk of high pesticide doses. JF - Clinical and Experimental Pharmacology and Physiology AU - Sutherland, T D AU - Horne, I AU - Weir, K M AU - Coppin, C W AU - Williams, M R AU - Selleck, M AU - Russell, R J AU - Oakeshott, JG AD - Tara Sutherland, CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia, Tara.Sutherland@csiro.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 817 EP - 821 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 31 IS - 11 SN - 0305-1870, 0305-1870 KW - Biotechnology and Bioengineering Abstracts KW - Detoxification KW - nerve agents KW - Fruits KW - Vegetables KW - Bioremediation KW - Protein engineering KW - Pesticide residues KW - Irrigation KW - Poisoning KW - Enzymes KW - Clinical trials KW - Risk factors KW - Pesticides KW - Prophylaxis KW - Antidotes KW - W 30950:Waste Treatment & Pollution Clean-up UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19431572?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Human+Prenatal+and+Postnatal+Exposure+to+Polybrominated+Diphenyl+Ethers%2C+Polychlorinated+Biphenyls%2C+Polychlorobiphenylols%2C+and+Pentachlorophenol&rft.au=Guvenius%2C+Daiva+Meironyte%3BAronsson%2C+Anette%3BEkman-Ordeberg%2C+Gunvor%3BBergman%2C+Ake%3BNoren%2C+Koidu&rft.aulast=Guvenius&rft.aufirst=Daiva&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1235&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-01-01 N1 - SuppNotes - Figures, 2; tables, 2; references, 34. N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - nerve agents; Detoxification; Fruits; Vegetables; Bioremediation; Protein engineering; Pesticide residues; Irrigation; Poisoning; Enzymes; Clinical trials; Risk factors; Pesticides; Prophylaxis; Antidotes DO - http://dx.doi.org/10.1111/j.1440-1681.2004.04088.x ER - TY - JOUR T1 - Rural and urban traffic fatalities, vehicle miles, and population density AN - 18033086; 6005727 AB - The purpose of this study was to evaluate the effect of population density on the rates of motor vehicle mortality in rural and urban areas, while controlling for vehicle miles traveled (VMT). Rural and urban data for traffic mortality, VMT, and population were obtained for each state from the Federal Highway Administration for 1998-2000. Linear regression was used to estimate the effect of population density, VMT per capita, southern location, and presence of a trauma system on mortality. Variation in rural mortality rate (per 100, 000 population) was proportional to rural VMT per capita, but population density and southern location were also independent predictors, together accounting for 91% of this variation. Variation in urban mortality rates was not affected by population density, but urban rates were also higher in the south. The exposure- based rural mortality rate (deaths per 100 million VMT) was inversely proportional to population density, which along with southern location explained 41% of the variation from state to state. The presence of a state trauma system did not measurably affect mortality. After controlling for VMT and southern location, state population density was a moderately strong predictor of rural but not urban traffic mortality rates. JF - Accident Analysis & Prevention AU - Clark, DE AU - Cushing, B M AD - Department of Surgery, Maine Medical Center, 887 Congress Street, Suite 210, Portland, ME 04102, USA, clarkd@mmc.org Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 967 EP - 972 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 36 IS - 6 SN - 0001-4575, 0001-4575 KW - Health & Safety Science Abstracts KW - Mortality KW - Motor vehicles KW - Population density KW - Accidents KW - Traffic safety KW - Urban areas KW - Rural areas KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18033086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Accident+Analysis+%26+Prevention&rft.atitle=Rural+and+urban+traffic+fatalities%2C+vehicle+miles%2C+and+population+density&rft.au=Clark%2C+DE%3BCushing%2C+B+M&rft.aulast=Clark&rft.aufirst=DE&rft.date=2004-11-01&rft.volume=36&rft.issue=6&rft.spage=967&rft.isbn=&rft.btitle=&rft.title=Accident+Analysis+%26+Prevention&rft.issn=00014575&rft_id=info:doi/10.1016%2Fj.aap.2003.10.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Population density; Rural areas; Urban areas; Mortality; Motor vehicles; Traffic safety; Accidents DO - http://dx.doi.org/10.1016/j.aap.2003.10.006 ER - TY - JOUR T1 - Efficient plant regeneration from suspension cells of Allium cepa L. AN - 17873009; 6283023 AB - Plant regeneration from calli of three cultivars of Allium cepa (Senshuki, O.Pki and Shojovaka) was investigated. Callus was induced on four variations of BDS medium containing different concentrations of 2,4-dichlorophenoxyacetic acid (2,4-D) and 6-benzyladenine (BAP). The regeneration frequency of calli of cvs. Senshuki and O.Pki subcultured on solid MS medium supplemented with BAP ranged from 50% to 80%; this frequency decreased to less than 30% after subculture in the dark in liquid BDS medium. By repeating the dark/light transitions of the culture protocol and by selecting for green cell clusters, we were able to increase the regeneration frequency to more than 80% in all three cultivars. These cell clusters maintained a high regeneration capacity in subsequent subcultures in the absence of light for 2 months. Most (97%) of the regenerated plantlets had a normal diploid karyotype (2n=16) that was identical to that of the mother plants, although 3% of the regenerated plants of cv. Shojovaka had a tetraploid karyotype. JF - Plant Cell Reports AU - Zhang, Wenbo AU - Lin, Xiaofei AU - Takano, Hiroyoshi AU - Takio, Susumu AU - Ono, Kanji AD - Kumamoto University, Kurokami, Kumamoto, 860-8555, Japan, stakio@gpo.kumamoto-u.ac.jp Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 371 EP - 376 PB - Springer-Verlag (Berlin), Heidelberger Platz 3 Berlin 14197 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 23 IS - 6 SN - 0721-7714, 0721-7714 KW - Onion KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - 2,4-D KW - Plantlets KW - Diploids KW - Regeneration KW - Allium cepa KW - Subculture KW - Callus KW - Cell culture KW - Karyotypes KW - Light effects KW - W 30965:Miscellaneous, Reviews KW - W2 32220:Cell culture UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17873009?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Cell+Reports&rft.atitle=Efficient+plant+regeneration+from+suspension+cells+of+Allium+cepa+L.&rft.au=Zhang%2C+Wenbo%3BLin%2C+Xiaofei%3BTakano%2C+Hiroyoshi%3BTakio%2C+Susumu%3BOno%2C+Kanji&rft.aulast=Zhang&rft.aufirst=Wenbo&rft.date=2004-11-01&rft.volume=23&rft.issue=6&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Plant+Cell+Reports&rft.issn=07217714&rft_id=info:doi/10.1007%2Fs00299-004-0839-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Allium cepa; Plantlets; Karyotypes; Subculture; Light effects; Cell culture; 2,4-D; Diploids; Callus; Regeneration DO - http://dx.doi.org/10.1007/s00299-004-0839-2 ER - TY - JOUR T1 - Completeness and timeliness of treatment for chlamydia within a sexual health service AN - 17855253; 6146127 AB - Prompt treatment of genital Chlamydia trachomatis infection will reduce the duration of infectiousness and further transmission of infection. In 2002, an audit was conducted to assess the completeness and timeliness of treatment for uncomplicated chlamydial infection at the Sydney Sexual Health Centre, Australia. Over a nine-month period, chlamydia was diagnosed in 250 patients, 97% of whom received appropriate treatment. The median duration between initial attendance and treatment was two days. Prompt delivery of treatment was facilitated by: initial treatment of patients likely to be chlamydia-infected; rapid availability of test results; urgent communication of positive test results; and effective procedures for recalling untreated patients. JF - International Journal of STD & AIDS AU - Chen, MY AU - Ryder, N AU - Donovan, B AD - Sydney Sexual Health Centre, Sydney Hospital, GPO Box 1614, Sydney, New South Wales 2001, Australia, chenm@sesahs.nsw.gov.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 762 EP - 764 VL - 15 IS - 11 SN - 0956-4624, 0956-4624 KW - Microbiology Abstracts B: Bacteriology KW - Communication KW - Chlamydia trachomatis KW - Infection KW - J 02849:Sexually-transmitted diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17855253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Completeness+and+timeliness+of+treatment+for+chlamydia+within+a+sexual+health+service&rft.au=Chen%2C+MY%3BRyder%2C+N%3BDonovan%2C+B&rft.aulast=Chen&rft.aufirst=MY&rft.date=2004-11-01&rft.volume=15&rft.issue=11&rft.spage=762&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Communication; Infection; Chlamydia trachomatis ER - TY - JOUR T1 - Immunity to vacuolar pathogens: What can we learn from Legionella? AN - 17813173; 6218448 AB - Intracellular pathogens can manipulate host cellular pathways to create specialized organelles. These pathogen-modified vacuoles permit the survival and replication of bacterial and protozoan microorganisms inside of the host cell. By establishing an atypical organelle, intracellular pathogens present unique challenges to the host immune system. To understand pathogenesis, it is important to not only investigate how these organisms create unique subcellular compartments, but to also determine how mammalian immune systems have evolved to detect and respond to pathogens sequestered in specialized vacuoles. Recent studies have identified genes in the respiratory pathogen Legionella pneumophila that are essential for establishing a unique endoplasmic reticulum-derived organelle inside of mammalian macrophages, making this pathogen an attractive model system for investigations on host immune responses that are specific for bacteria that establish vacuoles disconnected from the endocytic pathway. This review will focus on the host immune response to Legionella and highlight areas of Legionella research that should help elucidate host strategies to combat infections by intracellular pathogens. JF - Cellular Microbiology AU - Neild, Annie L AU - Roy, Craig R AD - Yale University School of Medicine, Section of Microbial Pathogenesis, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06536 USA, craig.roy@yale.edu Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1011 EP - 1018 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 6 IS - 11 SN - 1462-5814, 1462-5814 KW - Microbiology Abstracts B: Bacteriology KW - Macrophages KW - Cell survival KW - Respiratory tract diseases KW - Legionella pneumophila KW - Replication KW - Reviews KW - Immune system KW - Vacuoles KW - Immunity KW - Immune response KW - Pathogens KW - J 02833:Immune response and immune mechanisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17813173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cellular+Microbiology&rft.atitle=Immunity+to+vacuolar+pathogens%3A+What+can+we+learn+from+Legionella%3F&rft.au=Neild%2C+Annie+L%3BRoy%2C+Craig+R&rft.aulast=Neild&rft.aufirst=Annie&rft.date=2004-11-01&rft.volume=6&rft.issue=11&rft.spage=1011&rft.isbn=&rft.btitle=&rft.title=Cellular+Microbiology&rft.issn=14625814&rft_id=info:doi/10.1111%2Fj.1462-5822.2004.00450.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - SuppNotes - Figures, 1; references, 66. N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Legionella pneumophila; Pathogens; Respiratory tract diseases; Vacuoles; Immune system; Replication; Cell survival; Reviews; Immune response; Macrophages; Immunity DO - http://dx.doi.org/10.1111/j.1462-5822.2004.00450.x ER - TY - JOUR T1 - Effects of algal canopy clearance on plant, fish and macroinvertebrate communities on eastern Tasmanian reefs AN - 17760517; 6157629 AB - Changes in assemblages of plants, macroinvertebrates and fishes on three eastern Tasmanian reefs were monitored over 12 months in replicated control blocks and adjacent 10x12-m blocks cleared of fucoid, laminarian and dictyotalean algae. Removal of canopy-forming plants produced less change to biotic assemblages than reported in studies elsewhere, with the magnitude of change for fish and invertebrate taxa lower than variation between sites and comparable to variation between months. The introduced annual kelp Undaria pinnatifida exhibited the only pronounced response to canopy removal amongst algal taxa, with a fivefold increase in cleared blocks compared to control blocks. Marine reserves are suggested to assist reef communities resist invasion by U. pinnatifida, through an indirect mechanism involving increased predation pressure on sea urchins and reduced formation of urchin barrens that are amenable to U. pinnatifida propagation. Large invertebrates were more associated with turfing algae or the reef substratum than the macroalgal canopy. The herbivorous sea urchin Heliocidaris erythrogramma and abalone Haliotis ruber showed the strongest response to clearing amongst common macroinvertebrate species, with a halving of population numbers. Observed densities of the common monacanthid fish Acanthaluteres vittiger also declined by about 50%. The relatively high level of resistance shown by eastern Tasmanian reef biota to patch disturbance was attributed largely to high diversity and biomass of turfing macroalgae damping effects of canopy clearance. JF - Journal of Experimental Marine Biology and Ecology AU - Edgar, G J AU - Barrett, N S AU - Morton, A J AU - Samson, C R AD - Zoology Department, Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, GPO Box 252-05, Hobart, Tasmania 7001, Australia, g.edgar@utas.edu.au Y1 - 2004/11// PY - 2004 DA - November 2004 SP - 67 EP - 87 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 312 IS - 1 SN - 0022-0981, 0022-0981 KW - Abalone KW - ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; Ecology Abstracts KW - Algal canopy KW - Experimental clearance KW - Invertebrate KW - Marine protected area KW - Sublittoral KW - Turbo undulatus KW - Undaria pinnatifida KW - Urchin barrens KW - Reefs KW - Predation KW - Population density KW - Kelps KW - Interspecific relationships KW - Acanthaluteres vittiger KW - Canopies KW - Marine KW - Heliocidaris erythrogramma KW - Community composition KW - Species diversity KW - Marine parks KW - Zoobenthos KW - Haliotis ruber KW - Damping KW - Population number KW - O 1070:Ecology/Community Studies KW - Q1 08483:Species interactions: general KW - D 04330:Marine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17760517?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Inhalation+Exposure+of+Rats+to+Asphalt+Fumes+Generated+at+Paving+Temperatures+Alters+Pulmonary+Xenobiotic+Metabolism+Pathways+Without+Lung+Injury&rft.au=Ma%2C+Jane+YC%3BRengasamy%2C+Apavoo%3BFrazer%2C+Dave%3BBarger%2C+Mark+W%3BHubbs%2C+Ann+F%3BBattelli%2C+Lori%3BTomblyn%2C+Seith&rft.aulast=Ma&rft.aufirst=Jane&rft.date=2003-07-01&rft.volume=111&rft.issue=9&rft.spage=1215&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Reefs; Community composition; Interspecific relationships; Species diversity; Predation; Population density; Marine parks; Canopies; Kelps; Zoobenthos; Population number; Damping; Turbo undulatus; Heliocidaris erythrogramma; Acanthaluteres vittiger; Haliotis ruber; Undaria pinnatifida; Marine DO - http://dx.doi.org/10.1016/j.jembe.2004.06.005 ER - TY - JOUR T1 - Drainage morphometry and its influence on landform characteristics in a basaltic terrain, Central India-a remote sensing and GIS approach AN - 17699606; 6047018 AB - An attempt has been made to study drainage morphometry and its influence on landform processes, soil physical and land erosion characteristics in Vena river basin of basaltic terrain (Deccan traps), Nagpur district, Maharashtra, Central India. High Spatial Resolution Indian Remote Sensing Satellite (IRS)-ID Linear Image Self Scanning (LISS)-III sensor data of 7 March 2000 in conjunction with Survey Of India (SOI) topographical sheets (1:50, 000 scale) were used for systematic analysis of various morphometric, lithological and landform characteristics of the river basin. Morphometric analysis was carried out at sub basin level using Spatial Analysis System (SPANS ver. 7.0) GIS system to analyze the influence of drainage morphometry on landforms, soil depth, drainage, available water holding capacity (AWC) and land erosion characteristics. ten distinct landforms were identified in the basin based on visual interpretation of satellite sensor data. These are dissected ridges, isolated mounds, linear ridges, escarpments, plateau spurs, subdued plateau, rolling plains, foot slopes, narrow valleys and main valley floor. Very shallow soils exists on dissected ridges, isolated mounds, linear ridges, escarpments and plateau spurs covering the sub basins nos. 1, 5-7, 9, 15 and 16 and are associated with high drainage density (Dd), impermeable geology and high runoff conditions. High drainage density, high bifurcation ratio (Rb) and steep slopes are the main causative factors for the development of well-drained soils. The AWC is low in the soils of higher elevations covering the sub basins 1, 2, 3, 4, 7 and 9 whereas, it is very high at lower elevation in the sub basins nos. 12, 13 and 19. Sub basins nos. 1, 2, 5, 15 and 16, associated with high drainage density, stream frequency (Fu) and texture ratio (T) showed very severe to severe erosion. The analysis reveals that the influence of drainage morphometry is very significant in understanding the landform processes, soil physical properties and erosional characteristics. The study demonstrates that remotely sensed data and GIS based approach is found to be more appropriate than the conventional methods in evaluation and analysis of drainage morphometry, landforms and land resources and to understand their inter-relationships for planning and management at river basin level. JF - International Journal of Applied Earth Observation and Geoinformation AU - Reddy, GPO AU - Maji, A K AU - Gajbhiye, K S AD - National Bureau of Soil Survey and Land Use Planning, Amravati Road, Nagpur 440 010, India, obireddy@nbsslup.mah.nic.in Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1 EP - 16 PB - Elsevier Science Inc., Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.com] VL - 6 IS - 1 SN - 1569-8432, 1569-8432 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - SW 0835:Streamflow and runoff KW - Q2 02171:Dynamics of lakes and rivers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17699606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Applied+Earth+Observation+and+Geoinformation&rft.atitle=Drainage+morphometry+and+its+influence+on+landform+characteristics+in+a+basaltic+terrain%2C+Central+India-a+remote+sensing+and+GIS+approach&rft.au=Reddy%2C+GPO%3BMaji%2C+A+K%3BGajbhiye%2C+K+S&rft.aulast=Reddy&rft.aufirst=GPO&rft.date=2004-11-01&rft.volume=6&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Applied+Earth+Observation+and+Geoinformation&rft.issn=15698432&rft_id=info:doi/10.1016%2Fj.jag.2004.06.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.jag.2004.06.003 ER - TY - JOUR T1 - REPORT: Ecological risk assessment of transgenic pasture plants: a community gradient modelling approach AN - 17610429; 6225917 AB - The extension of transgene technology to pasture species presents new challenges for ecological risk assessment because, unlike most crops, pasture plants are well adapted for persistence in mixed plant communities and are an important source of invasive species worldwide. Despite this, the impact of transgenic pasture plants on native ecosystems remains relatively unstudied. Here we use a community gradient modelling approach to investigate the performance of subterranean clover containing a nutrition-enhancing transgene over a range of ecologically important grassland communities at a study site in south-eastern Australia. Our data, which were collected over a full annual growing season, show that the transgenic clover line has different seedling survival and seed dormancy breakdown rates than the commercial non-transgenic line, which suggests that transgenic populations will decline faster than non-transgenic ones in perennial native grassland communities but could, under optimal climatic conditions, have potentially higher growth rates in grazed annual grasslands. These results demonstrate that changes to ecologically important demographic parameters can occur in plants containing transgenes that are not typically considered fitness enhancing, and that genotype by environment interactions and management regimes that impact on these parameters may influence the invasiveness of transgenic plants. Our study also demonstrates the utility of incorporating plant community gradient modelling into ecological risk assessment protocols designed for transgenic pasture plants. JF - Ecology Letters AU - Godfree, Robert C AU - Young, Andrew G AU - Lonsdale, WMark AU - Woods, Matthew J AU - Burdon, Jeremy J AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, robert.godfree@csiro.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1077 EP - 1089 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 7 IS - 11 SN - 1461-023X, 1461-023X KW - Ecology Abstracts; Sustainability Science Abstracts KW - M3 1010:Issues in Sustainable Development KW - D 04110:Grasslands UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17610429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecology+Letters&rft.atitle=REPORT%3A+Ecological+risk+assessment+of+transgenic+pasture+plants%3A+a+community+gradient+modelling+approach&rft.au=Godfree%2C+Robert+C%3BYoung%2C+Andrew+G%3BLonsdale%2C+WMark%3BWoods%2C+Matthew+J%3BBurdon%2C+Jeremy+J&rft.aulast=Godfree&rft.aufirst=Robert&rft.date=2004-11-01&rft.volume=7&rft.issue=11&rft.spage=1077&rft.isbn=&rft.btitle=&rft.title=Ecology+Letters&rft.issn=1461023X&rft_id=info:doi/10.1111%2Fj.1461-0248.2004.00664.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - SuppNotes - Figures, 3; tables, 2. N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1111/j.1461-0248.2004.00664.x ER - TY - JOUR T1 - Influence of damping systems on building structures subject to seismic effects AN - 17531978; 6094877 AB - This paper investigates the response of multi-storey structures under simulated earthquake loads with friction dampers, viscoelastic dampers and combined friction-viscoelastic damping devices strategically located within shear walls. Consequently, evaluations are made as to how the damping systems affect the seismic response of these structures with respect to deflections and accelerations. In particular, this paper concentrates on the effects of damper types, configurations and their locations within the cut-outs of shear walls. The initial stiffness of the cut out section of the shear wall is removed and replaced by the stiffness and damping of the device. Influence of parameters of damper properties such as stiffness, damping coefficient, location, configuration and size are studied and evaluated using results obtained under several different earthquake scenarios. Structural models with cut outs at different heights are treated in order to establish the effectiveness of the dampers and their optimal placement. This conceptual study has demonstrated the feasibility of mitigating the seismic response of building structures by using embedded dampers. JF - Engineering Structures AU - Marko, J AU - Thambiratnam, D AU - Perera, N AD - School of Civil Engineering, Physical Infrastructure Center, Queensland University of Technology, GPO Box 2434, 2 George Street, Brisbane, Qld 4001, Australia, d.thambiratnam@qut.edu.au Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1939 EP - 1956 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 26 IS - 13 SN - 0141-0296, 0141-0296 KW - dampers KW - Health & Safety Science Abstracts KW - Earthquakes KW - Structural analysis KW - Seismic activity KW - H 15000:Civil/Structural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17531978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Engineering+Structures&rft.atitle=Influence+of+damping+systems+on+building+structures+subject+to+seismic+effects&rft.au=Marko%2C+J%3BThambiratnam%2C+D%3BPerera%2C+N&rft.aulast=Marko&rft.aufirst=J&rft.date=2004-11-01&rft.volume=26&rft.issue=13&rft.spage=1939&rft.isbn=&rft.btitle=&rft.title=Engineering+Structures&rft.issn=01410296&rft_id=info:doi/10.1016%2Fj.engstruct.2004.07.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Earthquakes; Seismic activity; Structural analysis DO - http://dx.doi.org/10.1016/j.engstruct.2004.07.008 ER - TY - JOUR T1 - Evaluation of Dendritic Gadolinium Complexes as MRI Contrast Agents AN - 17485432; 6110894 AB - A series of dendritic gadolinium complexes based on dendrimers with 1,4,7,10-tetraazacyclododecane as the core were synthesized. Both diethylenetriaminepentaacetic acid and pyridoxamine were incorporated to the amine groups on the surface to give the dendritic ligands. These dendritic ligands were then reacted with gadolinium chloride to yield the corresponding dendritic gadolinium complexes. The dendritic ligands and their gadolinium complexes were characterized by super(1)HNMR, IR, UV and elemental analysis. Relaxivity studies showed that the dendritic gadolinium complexes have higher relaxation effectiveness than that of the clinically used small molecular gadolinium complexes. Magnetic resonance imaging of the liver in rats indicated that the dendritic gadolinium complex containing pyridoxamine enhances the image contrast of the liver, provides prolonged intravascular duration and produces highly contrasted visualization of blood vessels in the liver. JF - Journal of Bioactive and Compatible Polymers AU - Yan, Guo-Ping AU - Bottle, SE AU - Zhuo, Ren-Xi AU - Wei, Li AU - Liu, Mai-Li AU - Li, Li-Yun AD - School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Q4001, Australia, guopyan@hotmail.com Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 453 EP - 465 VL - 19 IS - 6 SN - 0883-9115, 0883-9115 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - amines KW - Blood vessels KW - Magnetic resonance imaging KW - Gadolinium KW - Contrast media KW - Liver KW - Chloride KW - W4 150:Medical Imaging KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17485432?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Bioactive+and+Compatible+Polymers&rft.atitle=Evaluation+of+Dendritic+Gadolinium+Complexes+as+MRI+Contrast+Agents&rft.au=Yan%2C+Guo-Ping%3BBottle%2C+SE%3BZhuo%2C+Ren-Xi%3BWei%2C+Li%3BLiu%2C+Mai-Li%3BLi%2C+Li-Yun&rft.aulast=Yan&rft.aufirst=Guo-Ping&rft.date=2004-11-01&rft.volume=19&rft.issue=6&rft.spage=453&rft.isbn=&rft.btitle=&rft.title=Journal+of+Bioactive+and+Compatible+Polymers&rft.issn=08839115&rft_id=info:doi/10.1177%2F0883911504048375 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Gadolinium; Liver; Magnetic resonance imaging; amines; Blood vessels; Contrast media; Chloride DO - http://dx.doi.org/10.1177/0883911504048375 ER - TY - JOUR T1 - Breeding for high water-use efficiency AN - 17289428; 6062175 AB - There is a pressing need to improve the water-use efficiency of rain-fed and irrigated crop production. Breeding crop varieties with higher water-use efficiency is seen as providing part of the solution. Three key processes can be exploited in breeding for high water-use efficiency: (i) moving more of the available water through the crop rather than it being wasted as evaporation from the soil surface or drainage beyond the root zone or being left behind in the root zone at harvest; (ii) acquiring more carbon (biomass) in exchange for the water transpired by the crop, i.e. improving crop transpiration efficiency; (iii) partitioning more of the achieved biomass into the harvested product. The relative importance of any one of these processes will vary depending on how water availability varies during the crop cycle. However, these three processes are not independent. Targeting specific traits to improve one process may have detrimental effects on the other two, but there may also be positive interactions. Progress in breeding for improved water-use efficiency of rain-fed wheat is reviewed to illustrate the nature of some of these interactions and to highlight opportunities that may be exploited in other crops as well as potential pitfalls. For C sub(3) species, measuring carbon isotope discrimination provides a powerful means of improving water-use efficiency of leaf gas exchange, but experience has shown that improvements in leaf-level water-use efficiency may not always translate into higher crop water-use efficiency or yield. In fact, the reverse has frequently been observed. Reasons for this are explored in some detail. Crop simulation modelling can be used to assess the likely impact on water-use efficiency and yield of changing the expression of traits of interest. Results of such simulations indicate that greater progress may be achieved by pyramiding traits so that potential negative effects of individual traits are neutralized. DNA-based selection techniques may assist in such a strategy. JF - Journal of Experimental Botany AU - Condon, A G AU - Richards, R A AU - Rebetzke, G J AU - Farquhar, G D AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 2447 EP - 2460 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 55 IS - 407 SN - 0022-0957, 0022-0957 KW - Wheat KW - Water Resources Abstracts; Genetics Abstracts KW - G 07349:General KW - SW 1060:Conservation in agricultural use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17289428?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Botany&rft.atitle=Breeding+for+high+water-use+efficiency&rft.au=Condon%2C+A+G%3BRichards%2C+R+A%3BRebetzke%2C+G+J%3BFarquhar%2C+G+D&rft.aulast=Condon&rft.aufirst=A&rft.date=2004-11-01&rft.volume=55&rft.issue=407&rft.spage=2447&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Botany&rft.issn=00220957&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Prediction of Toxicant-Specific Gene Expression Signatures After Chemotherapeutic Treatment of Breast Cell Lines AN - 14719739; 10672636 AB - Results are presented from a study in which a panel of treated breast cell lines was used to identify toxicant-specific signatures for the chemotherapeutics, doxorubicin (DOX) and 5-fluorouracil (5FU). The results show that the cell lines exhibited distinct toxicant-specific patterns of response. Using two statistical methods for class prediction, sets of genes were identified that distinguished DOX- and 5FU-treated cells, which were used to predict the mechanism of etoposide, a drug that is mechanistically similar to DOX. Computational analyses were used to demonstrate that distinct transcriptional patterns could be identified for mechanistically dissimilar compounds and that toxicants with similar mechanisms could be classified accordingly. JF - Environmental Health Perspectives AU - Troester, Melissa A AU - Hoadley, Katherine A AU - Parker, Joel S AU - Perou, Charles M Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1607 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 16 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - TOXIC SUBSTANCES KW - DRUGS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14719739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prediction+of+Toxicant-Specific+Gene+Expression+Signatures+After+Chemotherapeutic+Treatment+of+Breast+Cell+Lines&rft.au=Troester%2C+Melissa+A%3BHoadley%2C+Katherine+A%3BParker%2C+Joel+S%3BPerou%2C+Charles+M&rft.aulast=Troester&rft.aufirst=Melissa&rft.date=2004-11-01&rft.volume=112&rft.issue=16&rft.spage=1607&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - TOXIC SUBSTANCES; DRUGS; GENETICS, HUMAN ER - TY - JOUR T1 - Effects of 1,3-Butadiene, Isoprene, and Their Photochemical Degradation Products on Human Lung Cells AN - 14718288; 10672452 AB - Human lung epithelial cells were interfaced with a smog chamber to assess the toxicity of 1,3-butadiene, isoprene, and their photochemical degradation products. The photochemical products of both compounds were found to increase lactate dehydrogenase release, as well as interleukin-8 expression, compared with clean-air controls, and the photochemical products were more potent inducers of interleukin-8 gene expression than the unreacted VOCs. Exposure to the parent compounds generated significant levels of cytotoxicity and interleukin-8 expression in A549 cells, but no significant effects were observed in differentiated human bronchial epithelial cells, which possibly represented regional differences in sensitivity within the respiratory epithelium. The main isoprene first-generation photochemical products formed were methacrolein, methyl vinyl ketone, formaldehyde, and ozone, while those formed from 1,3-butadiene included acrolein, formaldehyde, and O sub(3). JF - Environmental Health Perspectives AU - Doyle, Melanie AU - Sexton, Kenneth G AU - Jeffries, Harvey AU - Bridge, Kevin AU - Jaspers, Ilona Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1488 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CYTOTOXICITY KW - BUTADIENE KW - PROTEIN SYNTHESIS KW - VOLATILE ORGANIC COMPOUNDS KW - PULMONARY EFFECTS KW - PHOTOCHEMISTRY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718288?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+1%2C3-Butadiene%2C+Isoprene%2C+and+Their+Photochemical+Degradation+Products+on+Human+Lung+Cells&rft.au=Doyle%2C+Melanie%3BSexton%2C+Kenneth+G%3BJeffries%2C+Harvey%3BBridge%2C+Kevin%3BJaspers%2C+Ilona&rft.aulast=Doyle&rft.aufirst=Melanie&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1488&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CYTOTOXICITY; BUTADIENE; PROTEIN SYNTHESIS; PULMONARY EFFECTS; PHOTOCHEMISTRY; VOLATILE ORGANIC COMPOUNDS ER - TY - JOUR T1 - Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: a CaseControl Study in Newborn Boys AN - 14717166; 10672464 AB - Cryptorchidism, which is the maldescent of the testis, and hypospadias, which is the abnormal location of the orifice of the urethra, are among the most frequent congenital abnormalities in male births. In this study, the role of maternal and paternal occupational and dietary exposures to potential endocrine disruptors in the occurrences of the syndromes was investigated using a nested casecontrol strategy in Rotterdam, Netherlands. Parents were interviewed using a structured questionnaire to ascertain lifestyle and demographic data, as well as possible risk factors related to occupation and diet. Significant risk factors were found to be related to intrauterine growth, as well as to smoking among fathers and paternal self-reported exposure to pesticides and solvents. Multivariate analysis revealed that the important risk factors for hypospadias were small for gestational age at birth and the health status of the mother, while paternal smoking and pesticide exposure were associated significantly with cryptorchidism. JF - Environmental Health Perspectives AU - Pierik, Frank H AU - Burdorf, Alex AU - Deddens, James A AU - Juttmann, Rikard E AU - Weber, Rob FA Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1570 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HORMONAL EFFECTS KW - CIGARETTE SMOKE KW - DIET KW - RISK ASSESSMENT KW - NETHERLANDS KW - BIRTH DEFECTS, HUMAN KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14717166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Maternal+and+Paternal+Risk+Factors+for+Cryptorchidism+and+Hypospadias%3A+a+Case%26lt%3BND%26gt%3BControl+Study+in+Newborn+Boys&rft.au=Pierik%2C+Frank+H%3BBurdorf%2C+Alex%3BDeddens%2C+James+A%3BJuttmann%2C+Rikard+E%3BWeber%2C+Rob+FA&rft.aulast=Pierik&rft.aufirst=Frank&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1570&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; NETHERLANDS; HORMONAL EFFECTS; DIET; CIGARETTE SMOKE; BIRTH DEFECTS, HUMAN; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Relationship Between Composition and Toxicity of Motor Vehicle Emission Samples AN - 14717032; 10672458 JF - Environmental Health Perspectives AU - McDonald, Jacob D AU - Eide, Ingvar AU - Seagrave, JeanClare AU - Zielinska, Barbara AU - Whitney, Kevin AU - Lawson, Douglas R AU - Mauderly, Joe L Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1527 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - QUANTITATIVE ANALYSIS KW - AUTOMOBILE EMISSIONS KW - PARTICULATES KW - TOXICOLOGY KW - MUTAGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14717032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Relationship+Between+Composition+and+Toxicity+of+Motor+Vehicle+Emission+Samples&rft.au=McDonald%2C+Jacob+D%3BEide%2C+Ingvar%3BSeagrave%2C+JeanClare%3BZielinska%2C+Barbara%3BWhitney%2C+Kevin%3BLawson%2C+Douglas+R%3BMauderly%2C+Joe+L&rft.aulast=McDonald&rft.aufirst=Jacob&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1527&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; QUANTITATIVE ANALYSIS; AUTOMOBILE EMISSIONS; MUTAGENIC AGENTS; TOXICOLOGY; PARTICULATES ER - TY - JOUR T1 - Impact of the Phytoestrogen Content of Laboratory Animal Feed on the Gene Expression Profile of the Reproductive System in the Immature Female Rat AN - 14716933; 10672457 AB - Gene expression profiling was used to evaluate the effects of two diets with different phytoestrogen contents on the transcript profile of the uterus and ovaries in prepubertal SpragueDawley rats. One group was fed the standard laboratory rodent diet, Purina 5001, and the other was maintained on a casein-based diet. The standard diet contained phytoestrogens, mostly genistein and daidzein, while the casein-based diet was essentially phytoestrogen-free. One subgroup from each diet was dosed with 0.1 mu g/kg/d 17 alpha -ethylnylestradiol (EE) in peanut oil. No differences between groups were found in terms of body weight or uterine weight, and no clinical signs of toxicity were noted. Expression was found to be significantly different in 29 genes, however, although the response to the diet's composition was independent from the EE effect. JF - Environmental Health Perspectives AU - Naciff, Jorge M AU - Overmann, Gary J AU - Torontali, Suzanne M AU - Carr, Gregory J AU - Tiesman, Jay P AU - Daston, George P Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1519 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - HORMONAL EFFECTS KW - DIET KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Impact+of+the+Phytoestrogen+Content+of+Laboratory+Animal+Feed+on+the+Gene+Expression+Profile+of+the+Reproductive+System+in+the+Immature+Female+Rat&rft.au=Naciff%2C+Jorge+M%3BOvermann%2C+Gary+J%3BTorontali%2C+Suzanne+M%3BCarr%2C+Gregory+J%3BTiesman%2C+Jay+P%3BDaston%2C+George+P&rft.aulast=Naciff&rft.aufirst=Jorge&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1519&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t photos N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; HORMONAL EFFECTS; DIET; RODENTS ER - TY - JOUR T1 - Blood Lead Changes During Pregnancy and Postpartum with Calcium Supplementation AN - 14716126; 10672454 JF - Environmental Health Perspectives AU - Gulson, Brian L AU - Mizon, Karen J AU - Palmer, Jacqueline M AU - Korsch, Michael J AU - Taylor, Alan J AU - Mahaffey, Kathryn R Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1499 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CALCIUM KW - BLOOD LEAD LEVEL KW - PREGNANCY KW - FOOD SUPPLEMENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14716126?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Blood+Lead+Changes+During+Pregnancy+and+Postpartum+with+Calcium+Supplementation&rft.au=Gulson%2C+Brian+L%3BMizon%2C+Karen+J%3BPalmer%2C+Jacqueline+M%3BKorsch%2C+Michael+J%3BTaylor%2C+Alan+J%3BMahaffey%2C+Kathryn+R&rft.aulast=Gulson&rft.aufirst=Brian&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1499&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CALCIUM; PREGNANCY; BLOOD LEAD LEVEL; FOOD SUPPLEMENTS ER - TY - JOUR T1 - Androgenic and Estrogenic Response of Green Mussel Extracts from Singapore's Coastal Environment Using a Human Cell-Based Bioassay AN - 14715863; 10672449 JF - Environmental Health Perspectives AU - Bayen, Stephane AU - Gong, Yinhan AU - Chin, Hong Soon AU - Lee, Hian Kee AU - Leong, Yong Eu AU - Obbard, Jeffrey Philip Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1467 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MUSSELS KW - SINGAPORE KW - HORMONAL EFFECTS KW - BIOASSAY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14715863?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Androgenic+and+Estrogenic+Response+of+Green+Mussel+Extracts+from+Singapore%27s+Coastal+Environment+Using+a+Human+Cell-Based+Bioassay&rft.au=Bayen%2C+Stephane%3BGong%2C+Yinhan%3BChin%2C+Hong+Soon%3BLee%2C+Hian+Kee%3BLeong%2C+Yong+Eu%3BObbard%2C+Jeffrey+Philip&rft.aulast=Bayen&rft.aufirst=Stephane&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1467&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MUSSELS; SINGAPORE; HORMONAL EFFECTS; BIOASSAY ER - TY - JOUR T1 - Understanding the Spatial Clustering of Severe Acute Respiratory Syndrome (SARS) in Hong Kong AN - 14715565; 10672461 AB - Geographic information system technology was applied to map and visualize the severe acute respiratory syndrome (SARS) outbreak in Hong Kong in late 2002 and early 2003. Data on SARS occurrence were derived from case-contact interviews that were text based. Three levels of geostatistical analysis were carried out: an elementary analysis involving simple visual inspection of a geographic phenomenon; a cluster analysis that attempted to identify possible hot spots; and a contextual analysis to explain relationships among geographic phenomena. Results demonstrated exceptional spatial clustering of the cases. The daily animated series of kernel maps showed clearly that SARS was a highly localized disease, such that its route of transmission was unlikely to be through casual contact. JF - Environmental Health Perspectives AU - Lai, P C AU - Wong, C M AU - Hedley, A J AU - Lo, S V AU - Leung, P Y AU - Kong, J AU - Leung, G M Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1550 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HONG KONG KW - GEOGRAPHIC INFORMATION SYSTEMS KW - RESPIRATORY DISORDERS KW - SPATIAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14715565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Understanding+the+Spatial+Clustering+of+Severe+Acute+Respiratory+Syndrome+%28SARS%29+in+Hong+Kong&rft.au=Lai%2C+P+C%3BWong%2C+C+M%3BHedley%2C+A+J%3BLo%2C+S+V%3BLeung%2C+P+Y%3BKong%2C+J%3BLeung%2C+G+M&rft.aulast=Lai&rft.aufirst=P&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1550&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 14 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HONG KONG; GEOGRAPHIC INFORMATION SYSTEMS; RESPIRATORY DISORDERS; SPATIAL COMPARISONS ER - TY - JOUR T1 - Geographic Analysis of Blood Lead Levels in New York State Children Born 19941997 AN - 14714949; 10672465 AB - Data obtained from the New York State Department of Health on the blood lead levels of children born in the state between 1994 and 1997 were analyzed using a geographic information system to assess the geographic occurrence of high blood Pb and to detect trends over time. Socioeconomic data were collected from several sources, and the combined data were examined using multiple linear regression and simultaneous autoregression. Results revealed that blood Pb levels varied widely across the state, and a large portion of the variation in the data was described by the age of housing, education level, and percentage of African-American births in a community. Surprisingly, no association was found with population density. The blood Pb levels declined by a dramatic 44% over the 4-yr period, which was attributed presumably to greater public awareness, the remediation and replacement of older homes, and the phase-out of leaded gasoline. JF - Environmental Health Perspectives AU - Haley, Valerie B AU - Talbot, Thomas O Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1577 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HOUSING KW - BLOOD LEAD LEVEL KW - AREA COMPARISONS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - NEW YORK STATE KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14714949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Geographic+Analysis+of+Blood+Lead+Levels+in+New+York+State+Children+Born+1994%26lt%3BND%26gt%3B1997&rft.au=Haley%2C+Valerie+B%3BTalbot%2C+Thomas+O&rft.aulast=Haley&rft.aufirst=Valerie&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1577&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AREA COMPARISONS; GEOGRAPHIC INFORMATION SYSTEMS; HOUSING; BLOOD LEAD LEVEL; NEW YORK STATE; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Cumulative Dietary Energy Intake Determines the Onset of Puberty in Female Rats AN - 14714299; 10672450 AB - The relationship between total energy intake and sexual maturation in female rats was investigated using two types of dietary modification. In one, infant formula at different concentrations and sugar solutions were used to modulate metabolic energy intake, and in the second, open-formula synthetic phytoestrogen-free diets with a wide range of metabolizable energies were evaluated. Increasing the metabolizable energy density of the synthetic diet proportionally increased body weight and total energy intake, and increasing energy intake was associated with an increase in uterine weight. The uterotrophic activities of the infant formula and the diets were abolished by co-administration of the gonadotrophin-releasing hormone antagonist, Antarelix, but the uterotrophic activity of diethylstilbestrol was unaffected. The mean day of vaginal opening was advanced by the high-metabolizable energy diets and infant formula, while the body weight at vaginal opening was unaffected. JF - Environmental Health Perspectives AU - Odum, Jenny AU - Tinwell, Helen AU - Tobin, Graham AU - Ashby, John Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1472 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - METABOLIC ACTIVATION KW - HORMONAL EFFECTS KW - DIET KW - NUTRITION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14714299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cumulative+Dietary+Energy+Intake+Determines+the+Onset+of+Puberty+in+Female+Rats&rft.au=Odum%2C+Jenny%3BTinwell%2C+Helen%3BTobin%2C+Graham%3BAshby%2C+John&rft.aulast=Odum&rft.aufirst=Jenny&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1472&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 12 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - METABOLIC ACTIVATION; HORMONAL EFFECTS; DIET; NUTRITION ER - TY - JOUR T1 - Evidence for Concurrent Effects of Exposure to Environmental Cadmium and Lead on Hepatic CYP2A6 Phenotype and Renal Function Biomarkers in Nonsmokers AN - 14713911; 10672456 AB - In a group of healthy men and women from Thailand who had never smoked, the relationships between phenotype of hepatic cytochrome P4502A6 (CYP2A6), nephropathy, and exposure to cadmium and lead were examined. Blood and urine samples were collected and analyzed. A positive correlation was found between Cd burden and age, which was stronger in men than in women, but body iron store status was not correlated with Cd burden in either sex. Women's urinary zinc excretion showed an inverse correlation with age, but no such correlation was noted in men. Men had 36% higher urinary Zn excretion together with higher Zn:Cd and Zn:Pb ratios than did women. A positive correlation was found between CYP2A6 activity and Cd burden in both men and women, which remained statistically significant after controlling for age. In men, a Pb-suppressive effect on liver CYP2A6 was observed, which was not observed in women. JF - Environmental Health Perspectives AU - Satarug, Soisungwan AU - Nishijo, Muneko AU - Ujjin, Pailin AU - Vanavanitkun, Yuvaree AU - Baker, Jason R AU - Moore, Michael R Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1512 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - PROTEIN SYNTHESIS KW - CADMIUM KW - ZINC KW - HEPATOTOXICITY KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713911?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Evidence+for+Concurrent+Effects+of+Exposure+to+Environmental+Cadmium+and+Lead+on+Hepatic+CYP2A6+Phenotype+and+Renal+Function+Biomarkers+in+Nonsmokers&rft.au=Satarug%2C+Soisungwan%3BNishijo%2C+Muneko%3BUjjin%2C+Pailin%3BVanavanitkun%2C+Yuvaree%3BBaker%2C+Jason+R%3BMoore%2C+Michael+R&rft.aulast=Satarug&rft.aufirst=Soisungwan&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1512&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; ZINC; HEPATOTOXICITY; PROTEIN SYNTHESIS; LEAD; CADMIUM ER - TY - JOUR T1 - Induced Sputum Assessment in New York City Firefighters Exposed to World Trade Center Dust AN - 14713654; 10672463 AB - The induced sputum (IS) methodology was used to assess respired particulate matter and the inflammatory response of the lung in New York City firefighters after exposure to dust from the World Trade Center following the terrorist attack in September 2001. Inflammation was assessed by differential cell counts and by measuring metalloproteinase-9, a cytokine involved in airways inflammation and remodeling. Particulate matter was assessed by size distribution, mineral composition, and by comparison to settled dust samples collected at the site. The firefighters were examined ten months after the World Trade Center collapse. Results showed that differential counts for neutrophils and eosinophils increased with cumulative World Trade Center workday exposure intensity. The levels of metalloproteinase-9 were correlated positively with the percentage of neutrophils and negatively with the percentage of macrophages. In the firefighter IS samples, a high load of relatively large particles with irregularly shaped structures was found, and the particles were consistent chemically and mineralogically with exposures to aerosolized building debris and dust and smoke generated by the collapse and fires. JF - Environmental Health Perspectives AU - Fireman, Elizabeth M AU - Lerman, Yehuda AU - Ganor, Eliezer AU - Greif, Joel AU - Fireman-Shoresh, Sharon AU - Lioy, Paul J AU - Banauch, Gisela I Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1564 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - AIR POLLUTION EFFECTS KW - NEW YORK CITY KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713654?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Induced+Sputum+Assessment+in+New+York+City+Firefighters+Exposed+to+World+Trade+Center+Dust&rft.au=Fireman%2C+Elizabeth+M%3BLerman%2C+Yehuda%3BGanor%2C+Eliezer%3BGreif%2C+Joel%3BFireman-Shoresh%2C+Sharon%3BLioy%2C+Paul+J%3BBanauch%2C+Gisela+I&rft.aulast=Fireman&rft.aufirst=Elizabeth&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1564&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; AIR POLLUTION EFFECTS; PARTICULATES; NEW YORK CITY ER - TY - JOUR T1 - Xenoestrogen-Induced ERK-1 and ERK-2 Activation via Multiple Membrane-Initiated Signaling Pathways AN - 14713632; 10672451 AB - Using the pituitary tumor cell line, GH sub(3)/B6/F10, the ability of selected estrogen mimetics to produce rapid activation of extracellular-regulated kinases (ERKs) via various signaling pathways was investigated. The compounds used included dieldrin, endosulfan, o,p' DDE, p-nonylphenol, bisphenol A, and the natural phytoestrogen, coumestrol. A fixed cell-based enzyme linked immunoassay was used to monitor signaling events leading to ERK activation. All of the compounds, except for bisphenol A, elicited rapid membrane-initiated actions at very low concentrations compared with their reported potencies in classical genomic pathways. All active compounds were able to produce rapid ERK phosphorylations in the nanomolar concentration range, while coumestrol, nonylphenol, and endosulfan were also active in the subpicomolar range. Inhibitors that have been found to pinpoint various mechanisms leading to ERK phosphorylation differently affected each xenoestrogen response examined. JF - Environmental Health Perspectives AU - Bulayeva, Nataliya N AU - Watson, Cheryl S Y1 - 2004/11// PY - 2004 DA - Nov 2004 SP - 1481 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 15 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSE RESPONSE PROFILES KW - HORMONAL EFFECTS KW - DETERGENTS AND SOAPS KW - ORGANOCHLORINE PESTICIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14713632?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Xenoestrogen-Induced+ERK-1+and+ERK-2+Activation+via+Multiple+Membrane-Initiated+Signaling+Pathways&rft.au=Bulayeva%2C+Nataliya+N%3BWatson%2C+Cheryl+S&rft.aulast=Bulayeva&rft.aufirst=Nataliya&rft.date=2004-11-01&rft.volume=112&rft.issue=15&rft.spage=1481&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 19 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; HORMONAL EFFECTS; DETERGENTS AND SOAPS; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Growth responses, physiology and decay associated with pruning plantation-grown Eucalyptus globulus Labill. and E. nitens (Deane and Maiden) Maiden AN - 17763908; 6144416 AB - Detailed studies have been undertaken to define pruning regimes for Eucalyptus nitens, but little is known of E. globulus responses to pruning although this is a more commonly planted species. This paper describes experiments that aimed to identify (a) levels of pruning that reduce E. globulus growth, (b) physiological processes contributing to those growth responses, (c) the incidence of decay and factors influencing decay incidence following pruning of E. globulus, and (d) comparative responses of E. nitens and E. globulus to live branch pruning. Results of a field experiment indicated that removal of between 30 and 50% of the crown length was appropriate for E. globulus plantations verging on canopy closure. The significant reduction in height growth associated with removal of 50 or 70% of crown length suggested pruning should remain below 50% of crown length if reduced stem growth of pruned trees was to be avoided. Stem volume was only significantly reduced over the period of the experiment by 70% pruning, but it was estimated that standing volume following removal of 50% of crown length would be reduced by 82m super(3)ha super(-) super(1) over a 20-year rotation if there were no other silvicultural interventions. The growth responses observed were probably related to large reductions in leaf area following 50 or 70% removal of crown length. Trees responded to pruning by changing patterns of biomass partitioning to favour stem growth at the expense of branch growth. A glasshouse study determined that light-saturated net CO sub(2) uptake (A sub(m) sub(a) sub(x)) increased following pruning. E. nitens seedlings had both a higher baseline A sub(m) sub(a) sub(x) and higher A sub(m) sub(a) sub(x) following pruning than did E. globulus, which could partially explain the greater effect of pruning on E. globulus growth than has been observed for E. nitens in other studies. This result, as well as apparently different patterns of foliage distribution through the crowns of E. globulus and E. nitens, suggested that models of pruning responses need to be parameterised for both species. In addition, a more conservative pruning regime may be appropriate for E. globulus than E. nitens. Pruning increased the frequency of branch traces with decay infection, and there was a trend towards increasing decay outbreaks with increasing pruning severity. Decay outbreaks were more likely to occur following pruning of high angle or larger diameter branches. JF - Forest Ecology and Management AU - Pinkard, E A AU - Mohammed, C AU - Beadle, CL AU - Hall, M F AU - Worledge, D AU - Mollon, A AD - Cooperative Research Centre for Sustainable Production Forestry, Private Bag 12, GPO Hobart 7000, Australia, libby.pinkard@ffp.csiro.au Y1 - 2004/10/25/ PY - 2004 DA - 2004 Oct 25 SP - 263 EP - 277 VL - 200 IS - 1-3 SN - 0378-1127, 0378-1127 KW - Ecology Abstracts KW - Forest management KW - Foliage KW - Branches KW - Trees KW - Canopies KW - Decay KW - Pruning KW - Carbon dioxide KW - Plantations KW - Eucalyptus globulus KW - Eucalyptus nitens KW - D 04700:Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17763908?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forest+Ecology+and+Management&rft.atitle=Growth+responses%2C+physiology+and+decay+associated+with+pruning+plantation-grown+Eucalyptus+globulus+Labill.+and+E.+nitens+%28Deane+and+Maiden%29+Maiden&rft.au=Pinkard%2C+E+A%3BMohammed%2C+C%3BBeadle%2C+CL%3BHall%2C+M+F%3BWorledge%2C+D%3BMollon%2C+A&rft.aulast=Pinkard&rft.aufirst=E&rft.date=2004-10-25&rft.volume=200&rft.issue=1-3&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=Forest+Ecology+and+Management&rft.issn=03781127&rft_id=info:doi/10.1016%2Fj.foreco.2004.07.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eucalyptus nitens; Eucalyptus globulus; Pruning; Decay; Branches; Plantations; Trees; Carbon dioxide; Canopies; Foliage; Forest management DO - http://dx.doi.org/10.1016/j.foreco.2004.07.004 ER - TY - JOUR T1 - Engineering high-level aluminum tolerance in barley with the ALMT1 gene. AN - 66990510; 15471989 AB - Acidity is a serious limitation to plant production on many of the world's agricultural soils. Toxic aluminium (Al) cations solubilized by the acidity rapidly inhibit root growth and limit subsequent uptake of water and nutrients. Recent work has shown that the ALMT1 gene of wheat (Triticum aestivum) encodes a malate transporter that is associated with malate efflux and Al tolerance. We generated transgenic barley (Hordeum vulgare) plants expressing ALMT1 and assessed their ability to exude malate and withstand Al stress. ALMT1 expression in barley conferred an Al-activated efflux of malate with properties similar to those of Al-tolerant wheat. The transgenic barley showed a high level of Al tolerance when grown in both hydroponic culture and on acid soils. These findings provide additional evidence that ALMT1 is a major Al-tolerance gene and demonstrate its ability to confer effective tolerance to acid soils through a transgenic approach in an important crop species. JF - Proceedings of the National Academy of Sciences of the United States of America AU - Delhaize, Emmanuel AU - Ryan, Peter R AU - Hebb, Diane M AU - Yamamoto, Yoko AU - Sasaki, Takayuki AU - Matsumoto, Hideaki AD - Commonwealth Scientific and Industrial Research Organization Plant Industry, GPO Box 1600, Canberra ACT 2601, Australia. manny.delhaize@csiro.au Y1 - 2004/10/19/ PY - 2004 DA - 2004 Oct 19 SP - 15249 EP - 15254 VL - 101 IS - 42 SN - 0027-8424, 0027-8424 KW - DNA, Plant KW - 0 KW - Malates KW - Plant Proteins KW - Recombinant Proteins KW - malic acid KW - 817L1N4CKP KW - Aluminum KW - CPD4NFA903 KW - Index Medicus KW - Biological Transport, Active -- drug effects KW - Base Sequence KW - DNA, Plant -- genetics KW - Recombinant Proteins -- metabolism KW - Plants, Genetically Modified KW - Genetic Engineering KW - Plant Proteins -- genetics KW - Recombinant Proteins -- genetics KW - Plant Proteins -- metabolism KW - Malates -- metabolism KW - Hordeum -- drug effects KW - Hordeum -- genetics KW - Genes, Plant KW - Aluminum -- toxicity KW - Hordeum -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66990510?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Engineering+high-level+aluminum+tolerance+in+barley+with+the+ALMT1+gene.&rft.au=Delhaize%2C+Emmanuel%3BRyan%2C+Peter+R%3BHebb%2C+Diane+M%3BYamamoto%2C+Yoko%3BSasaki%2C+Takayuki%3BMatsumoto%2C+Hideaki&rft.aulast=Delhaize&rft.aufirst=Emmanuel&rft.date=2004-10-19&rft.volume=101&rft.issue=42&rft.spage=15249&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.issn=00278424&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-22 N1 - Date created - 2004-10-20 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Planta. 2003 Sep;217(5):794-800 [12734756] Plant J. 2004 Mar;37(5):645-53 [14871306] Curr Biol. 1996 Mar 1;6(3):325-30 [8805250] Science. 1997 Jun 6;276(5318):1566-8 [9171061] Plant Physiol. 2000 Mar;122(3):657-65 [10712528] Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11655-60 [11027363] Plant Physiol. 2003 Aug;132(4):2256-66 [12913180] Plant Physiol. 2001 Mar;125(3):1459-72 [11244125] Plant Physiol. 2001 Apr;125(4):2059-67 [11299385] Trends Plant Sci. 2001 Jun;6(6):273-8 [11378470] Plant Physiol. 2001 Dec;127(4):1836-44 [11743127] Plant Cell. 2003 May;15(5):1131-42 [12724539] Plant Physiol. 2003 Aug;132(4):2205-17 [12913175] Plant Cell Physiol. 2000 Sep;41(9):1030-7 [11100775] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Strain differences of cadmium-induced hepatotoxicity in Wistar-Imamichi and Fischer 344 rats: involvement of cadmium accumulation. AN - 66876101; 15363594 AB - We previously reported that Wistar-Imamichi (WI) rats have a strong resistance to cadmium (Cd)-induced lethality compared to other strains such as Fischer 344 (Fischer) rats. The present study was designed to establish biochemical and histological differences in Cd toxicity in WI and Fischer rats, and to clarify the mechanistic basis of these strain differences. A single Cd (4.5 mg/kg, s.c.) treatment caused a significant increase in serum alanine aminotransferase activity, indicative of hepatotoxicity, in Fischer rats, but did not in WI rats. This difference in hepatotoxic response to Cd was supported by pathological analysis. After treatment with Cd at doses of 3.0, 3.5 and 4.5 mg/kg, the hepatic and renal accumulation of Cd was significantly lower in the WI rats than in the Fischer rats, indicating a kinetic mechanism for the observed strain differences in Cd toxicity. Thus, the remarkable resistance to Cd-induced hepatotoxicity in WI rats is associated, at least in part, with a lower tissue accumulation of the metal. Hepatic and renal zinc (Zn) contents after administration were similarly lower in WI than in Fischer rats. When Zn was administered in combination with Cd to Fischer rats, it decreased Cd contents in the liver and kidney, and exhibited a significant protective effect against the toxicity of Cd. We propose the possibility that Zn transporter plays an important role in the strain difference of Cd toxicity in WI and Fischer rats. JF - Toxicology AU - Shimada, Hideaki AU - Takamure, Yasutaka AU - Shimada, Akinori AU - Yasutake, Akira AU - Waalkes, Michael P AU - Imamura, Yorishige AD - Faculty of Education, Kumamoto University, 2-40-1, Kurokami, 860-8555, Japan. hshimada@gpo.kumamoto-u.ac.jp Y1 - 2004/10/15/ PY - 2004 DA - 2004 Oct 15 SP - 189 EP - 197 VL - 203 IS - 1-3 SN - 0300-483X, 0300-483X KW - Cadmium KW - 00BH33GNGH KW - Metallothionein KW - 9038-94-2 KW - Iron KW - E1UOL152H7 KW - Alanine Transaminase KW - EC 2.6.1.2 KW - Zinc KW - J41CSQ7QDS KW - Index Medicus KW - Animals KW - Kidney -- metabolism KW - Liver -- pathology KW - Kidney -- pathology KW - Iron -- pharmacology KW - Alanine Transaminase -- metabolism KW - Zinc -- metabolism KW - Liver -- metabolism KW - Blood Urea Nitrogen KW - Iron -- metabolism KW - Rats KW - Zinc -- pharmacology KW - Rats, Inbred F344 KW - Rats, Wistar KW - Species Specificity KW - Male KW - Metallothionein -- metabolism KW - Cadmium Poisoning -- metabolism KW - Cadmium -- metabolism KW - Chemical and Drug Induced Liver Injury -- pathology KW - Cadmium Poisoning -- complications KW - Chemical and Drug Induced Liver Injury -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66876101?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Strain+differences+of+cadmium-induced+hepatotoxicity+in+Wistar-Imamichi+and+Fischer+344+rats%3A+involvement+of+cadmium+accumulation.&rft.au=Shimada%2C+Hideaki%3BTakamure%2C+Yasutaka%3BShimada%2C+Akinori%3BYasutake%2C+Akira%3BWaalkes%2C+Michael+P%3BImamura%2C+Yorishige&rft.aulast=Shimada&rft.aufirst=Hideaki&rft.date=2004-10-15&rft.volume=203&rft.issue=1-3&rft.spage=189&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-19 N1 - Date created - 2004-09-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Perspective: Emergency medicine and environmental activism AN - 745604925; 6218550 AB - Clearfell, burn and sow silviculture is promoted as being the most scientific method of harvesting wet sclerophyll forests in Tasmania. However, it fails to take into account wider social and global environmental issues such as climate change and the carbon cycle. This paper describes an emergency physician's role in the continuing debate surrounding the management of Tasmania's old-growth forests. Like evidence-based medicine, the use of science in this context has its limitations, and such comparisons are discussed. JF - Emergency Medicine Australasia AU - Couser, Geoff AD - Dr Geoff Couser, Department of Emergency Medicine, Royal Hobart Hospital, GPO Box 1061, Hobart, Tas. 7001, Australia, gcouser@utas.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 469 EP - 472 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 16 IS - 5-6 SN - 1742-6731, 1742-6731 KW - Sustainability Science Abstracts KW - Burns KW - silviculture KW - harvesting KW - Climatic changes KW - Carbon cycle KW - Forests KW - environmentalism KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745604925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Emergency+Medicine+Australasia&rft.atitle=Perspective%3A+Emergency+medicine+and+environmental+activism&rft.au=Couser%2C+Geoff&rft.aulast=Couser&rft.aufirst=Geoff&rft.date=2004-10-01&rft.volume=16&rft.issue=5-6&rft.spage=469&rft.isbn=&rft.btitle=&rft.title=Emergency+Medicine+Australasia&rft.issn=17426731&rft_id=info:doi/10.1111%2Fj.1742-6723.2004.00652.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - SuppNotes - References, 13. N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Burns; silviculture; harvesting; Climatic changes; Carbon cycle; Forests; environmentalism DO - http://dx.doi.org/10.1111/j.1742-6723.2004.00652.x ER - TY - JOUR T1 - Repellency of essential oils of some Kenyan plants against Anopheles gambiae. AN - 66960927; 15474566 AB - Essential oils of six plants growing in Kenya were screened for repellent activities against Anopheles gambiae sensu stricto. The oils of Conyza newii (Compositeae) and Plectranthus marrubioides (Labiateae) were the most repellent (RD50=8.9 x 10(-5) mg cm(-2), 95% CI) followed by Lippia javanica (Verbenaceae), Lippia ukambensis (Verbenaceae), Tetradenia riparia, (Iboza multiflora) (Labiateae) and Tarchonanthus camphoratus (Compositeae). Eight constituents of the different oils (perillyl alcohol, cis-verbenol, cis-carveol, geraniol, citronellal, perillaldehyde, caryophyllene oxide and a sesquiterpene alcohol) exhibited relatively high repellency. Four synthetic blends of the major components (present in > or = 1.5%) of the essential oils were found to exhibit comparable repellent activity to the parent oils. JF - Phytochemistry AU - Omolo, Maurice O AU - Okinyo, Denis AU - Ndiege, Isaiah O AU - Lwande, Wilber AU - Hassanali, Ahmed AD - Chemistry Department, School of Pure and Applied Sciences, Kenyatta University, PO Box 43844, GPO 00100, Nairobi, Kenya. Y1 - 2004/10// PY - 2004 DA - October 2004 SP - 2797 EP - 2802 VL - 65 IS - 20 SN - 0031-9422, 0031-9422 KW - Insect Repellents KW - 0 KW - Oils, Volatile KW - Index Medicus KW - Animals KW - Kenya KW - Plants -- chemistry KW - Oils, Volatile -- pharmacology KW - Oils, Volatile -- chemistry KW - Anopheles gambiae -- drug effects KW - Insect Repellents -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66960927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Phytochemistry&rft.atitle=Repellency+of+essential+oils+of+some+Kenyan+plants+against+Anopheles+gambiae.&rft.au=Omolo%2C+Maurice+O%3BOkinyo%2C+Denis%3BNdiege%2C+Isaiah+O%3BLwande%2C+Wilber%3BHassanali%2C+Ahmed&rft.aulast=Omolo&rft.aufirst=Maurice&rft.date=2004-10-01&rft.volume=65&rft.issue=20&rft.spage=2797&rft.isbn=&rft.btitle=&rft.title=Phytochemistry&rft.issn=00319422&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-01-31 N1 - Date created - 2004-10-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Governing street-based injecting drug users: a critique of heroin overdose prevention in Australia. AN - 66701993; 15246182 AB - This article provides a critical analysis of existing approaches to the prevention of heroin overdose in Australia. It draws on almost 2 years of ethnographic research with street-based injecting drug users (IDUs), street-based sex workers and service providers in Melbourne, Australia's second largest city, and on recent anthropological and sociological work on governmentality. The substantive sections of the article argue: (1) that heroin overdose prevention in Australia contains implicit or explicit assumptions of rationality and personal autonomy, continues to emphasise individual behaviour change and inscribes a self-disciplined, self-aware, self-regulating subject; and (2) that the social, cultural and economic realities--the 'lived experience'--of street-based IDUs and sex workers may undermine or hinder the successful adoption of overdose prevention strategies. The paper concludes by arguing that the 'chaotic' practices of street-based IDUs and sex workers arise in response to particular 'risk environments', and that individually focused overdose prevention strategies, while an important first step, need to be complemented by measures addressing the macro- and micro-aspects of risk environments. JF - Social science & medicine (1982) AU - Moore, David AD - National Drug Research Institute, Curtin University of Technology, GPO Box U1987, Perth WA 6845, Australia. d.moore@curtin.edu.au Y1 - 2004/10// PY - 2004 DA - October 2004 SP - 1547 EP - 1557 VL - 59 IS - 7 SN - 0277-9536, 0277-9536 KW - Index Medicus KW - Victoria KW - Risk-Taking KW - Humans KW - Adult KW - Australia KW - Social Conditions KW - Female KW - Anthropology, Cultural KW - Social Control, Formal KW - Sex Work -- psychology KW - Drug Overdose -- prevention & control KW - Heroin Dependence -- psychology KW - Substance Abuse, Intravenous -- psychology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66701993?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+science+%26+medicine+%281982%29&rft.atitle=Governing+street-based+injecting+drug+users%3A+a+critique+of+heroin+overdose+prevention+in+Australia.&rft.au=Moore%2C+David&rft.aulast=Moore&rft.aufirst=David&rft.date=2004-10-01&rft.volume=59&rft.issue=7&rft.spage=1547&rft.isbn=&rft.btitle=&rft.title=Social+science+%26+medicine+%281982%29&rft.issn=02779536&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-19 N1 - Date created - 2004-07-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The 9/11 Commission Report: Final Report of the National Commission on Terrorist Attacks upon the United States AN - 59705764; 200607713 JF - Medunarodne studije AU - Nakic, Mladen AU - Nakic, Mladen Y1 - 2004/10// PY - 2004 DA - October 2004 SP - 201 EP - 204 VL - 4 IS - 3-4 SN - 1332-4756, 1332-4756 KW - article KW - 9105: politics; national-level politics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59705764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Medunarodne+studije&rft.atitle=The+9%2F11+Commission+Report%3A+Final+Report+of+the+National+Commission+on+Terrorist+Attacks+upon+the+United+States&rft.au=Nakic%2C+Mladen%3BU.S.+Congress&rft.aulast=Nakic&rft.aufirst=Mladen&rft.date=2004-10-01&rft.volume=4&rft.issue=3-4&rft.spage=201&rft.isbn=&rft.btitle=&rft.title=Medunarodne+studije&rft.issn=13324756&rft_id=info:doi/ LA - Serbo-Croatian with Roman alphabet/Croatian DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - SuppNotes - Edition date: 2004. Language of document reviewed: English. N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Developing a Comprehensive Pesticide Health Effects Tracking System for an Urban Setting: New York City's Approach AN - 21430237; 12429537 AB - In recent years, there have been substantial investments and improvements in federal and state surveillance systems to track the health effects from pesticide exposure. These surveillance systems help to identify risk factors for occupational exposure to pesticides, patterns in poisonings, clusters of disease, and populations at risk of exposure from pesticide use. Data from pesticide use registries and recent epidemiologic evidence pointing to health risks from urban residential pesticide use make a strong case for understanding better the sale, application, and use of pesticides in cities. In this article, we describe plans for the development of a pesticide tracking system for New York City that will help to elucidate where and why pesticides are used, potential risks to varied populations, and the health consequences of their use. The results of an inventory of data sources are presented along with a description of their relevance to pesticide tracking. We also discuss practical, logistical, and methodologic difficulties of linking multiple secondary data sources with different levels of person, place, and time descriptors. JF - Environmental Health Perspectives AU - Kass, Daniel E AU - Thier, Audrey L AU - Leighton, Jessica AU - Cone, James E AU - Jeffery, Nancy L Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1419 EP - 1423 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Risk assessment KW - USA, New York, New York City KW - Pesticides KW - Poisoning KW - Occupational exposure KW - Urban areas KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21430237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developing+a+Comprehensive+Pesticide+Health+Effects+Tracking+System+for+an+Urban+Setting%3A+New+York+City%27s+Approach&rft.au=Kass%2C+Daniel+E%3BThier%2C+Audrey+L%3BLeighton%2C+Jessica%3BCone%2C+James+E%3BJeffery%2C+Nancy+L&rft.aulast=Kass&rft.aufirst=Daniel&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1419&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Risk assessment; Pesticides; Poisoning; Occupational exposure; Urban areas; USA, New York, New York City ER - TY - JOUR T1 - Does Particulate Air Pollution Contribute to Infant Death? A Systematic Review AN - 21423601; 12429543 AB - There is now substantial evidence that both short- and long-term increases in ambient air pollution are associated with increased mortality and morbidity in adults and children. Children's health is particularly vulnerable to environmental pollution, and infant mortality is still a major contributor to childhood mortality. In this systematic review we summarize and evaluate the current level of epidemiologic evidence of an association between particulate air pollution and infant mortality. We identified relevant publications using database searches with a comprehensive list of search terms and other established search methods. We included articles in the review according to specified inclusion criteria. Fifteen studies met our inclusion criteria. Evidence of an association between particulate air pollution and infant mortality in general was inconsistent, being reported from locations with largely comparable pollution levels. There was some evidence that the strength of association with particulate matter differed by subgroups of infant mortality. It was more consistent for postneonatal mortality due to respiratory causes and sudden infant death syndrome. Differential findings for various mortality subgroups within studies suggest a stronger association of particulate air pollution with some causes of infant death. Research is needed to confirm and clarify these links, using the most appropriate methodologies for exposure assessment and control of confounders. JF - Environmental Health Perspectives AU - Glinianaia, Svetlana V AU - Rankin, Judith AU - Bell, Ruth AU - Pless-Mulloli, Tanja AU - Howel, Denise Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1365 EP - 1371 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts; Environment Abstracts KW - Mortality KW - pollution levels KW - infant mortality KW - Pollution effects KW - Particulates KW - Children KW - Morbidity KW - Air pollution KW - Reviews KW - vulnerability KW - Infants KW - sudden infant death syndrome KW - P 0000:AIR POLLUTION KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423601?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Does+Particulate+Air+Pollution+Contribute+to+Infant+Death%3F+A+Systematic+Review&rft.au=Glinianaia%2C+Svetlana+V%3BRankin%2C+Judith%3BBell%2C+Ruth%3BPless-Mulloli%2C+Tanja%3BHowel%2C+Denise&rft.aulast=Glinianaia&rft.aufirst=Svetlana&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1365&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Air pollution; Mortality; pollution levels; infant mortality; Reviews; Pollution effects; vulnerability; Particulates; Children; Morbidity; sudden infant death syndrome; Infants ER - TY - JOUR T1 - Quinones and Aromatic Chemical Compounds in Particulate Matter Induce Mitochondrial Dysfunction: Implications for Ultrafine Particle Toxicity AN - 21423335; 12429542 AB - Particulate pollutants cause adverse health effects through the generation of oxidative stress. A key question is whether these effects are mediated by the particles or their chemical compounds. In this article we show that aliphatic, aromatic, and polar organic compounds, fractionated from diesel exhaust particles (DEPs), exert differential toxic effects in RAW 264.7 cells. Cellular analyses showed that the quinone-enriched polar fraction was more potent than the polycyclic aromatic hydrocarbon (PAH)-enriched aromatic fraction in O2 .- generation, decrease of membrane potential (Delta-Psi m), loss of mitochondrial membrane mass, and induction of apoptosis. A major effect of the polar fraction was to promote cyclosporin A (CsA)-sensitive permeability transition pore (PTP) opening in isolated liver mitochondria. This opening effect is dependent on a direct effect on the PTP at low doses as well as on an effect on Delta-Psi m at high doses in calcium (Ca2+)-loaded mitochondria. The direct PTP effect was mimicked by redox-cycling DEP quinones. Although the aliphatic fraction failed to perturb mitochondrial function, the aromatic fraction increased the Ca2+ retention capacity at low doses and induced mitochondrial swelling and a decrease in Delta-Psi m at high doses. This swelling effect was mostly CsA insensitive and could be reproduced by a mixture of PAHs present in DEPs. These chemical effects on isolated mitochondria could be reproduced by intact DEPs as well as ambient ultrafine particles (UFPs). In contrast, commercial polystyrene nanoparticles failed to exert mitochondrial effects. These results suggest that DEP and UFP effects on the PTP and Delta-Psi m are mediated by adsorbed chemicals rather than the particles themselves. JF - Environmental Health Perspectives AU - Xia, Tian AU - Korge, Paavo AU - Weiss, James N AU - Li, Ning Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1347 EP - 1358 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Permeability KW - Membranes KW - Calcium KW - Liver KW - polycyclic aromatic hydrocarbons KW - Particulates KW - Toxicity KW - Diesel engines KW - oxidative stress KW - ENA 09:Land Use & Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21423335?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Quinones+and+Aromatic+Chemical+Compounds+in+Particulate+Matter+Induce+Mitochondrial+Dysfunction%3A+Implications+for+Ultrafine+Particle+Toxicity&rft.au=Xia%2C+Tian%3BKorge%2C+Paavo%3BWeiss%2C+James+N%3BLi%2C+Ning&rft.aulast=Xia&rft.aufirst=Tian&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1347&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Permeability; Calcium; Membranes; Liver; polycyclic aromatic hydrocarbons; Toxicity; Particulates; Diesel engines; oxidative stress ER - TY - JOUR T1 - Using the Behavioral Risk Factor Surveillance System (BRFSS) for Exposure Tracking: Experiences from Washington State AN - 21422586; 12429536 AB - One of the goals of the National Environmental Public Health Tracking Network is to link environmental data with chronic disease data as a means of improving our understanding of the environmental determinants of disease. Such efforts will rely on the ongoing collection of population exposure information, and there are few systems in place to track population exposures. In many cases, exposures can be estimated by combining environmental contaminant data with data about human behaviors. The Behavioral Risk Factor Surveillance System (BRFSS) provides a good opportunity to implement tracking of exposure-related behaviors. Washington State has used the BRFSS to collection information on environmentally related knowledge, attitudes, and behaviors. In this article we present case studies of modules covering drinking water, perceptions of environmental risk, and radon awareness and testing. Data on exposure-related behaviors have been useful for population exposure assessments and program evaluation. Questions about knowledge and attitudes and perceptions of environmental issues were not as useful because they lacked sufficient detail from which to modify existing education efforts. In some cases these data had not been used at all, indicating that the need for the data had not been well established. National development efforts should focus on compiling existing questions and developing questions on topics that are a priority at the state and national levels to be included as core questions and optional modules in future BRFSS surveys. JF - Environmental Health Perspectives AU - Laflamme, Denise M AU - VanDerslice, James A Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1428 EP - 1433 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - case studies KW - USA, Washington KW - Data collection KW - Education KW - Perception KW - Human factors KW - Drinking water KW - attitudes KW - Radon KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21422586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+the+Behavioral+Risk+Factor+Surveillance+System+%28BRFSS%29+for+Exposure+Tracking%3A+Experiences+from+Washington+State&rft.au=Laflamme%2C+Denise+M%3BVanDerslice%2C+James+A&rft.aulast=Laflamme&rft.aufirst=Denise&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1428&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - case studies; Education; Data collection; Perception; Human factors; Drinking water; Radon; attitudes; USA, Washington ER - TY - JOUR T1 - Identifying Priority Health Conditions, Environmental Data, and Infrastructure Needs: A Synopsis of the Pew Environmental Health Tracking Project AN - 21417289; 12429547 AB - In this article we describe the methodologic approaches of the Pew Environmental Health Commission at the Johns Hopkins Bloomberg School of Public Health used to identify priority environmental health conditions and develop recommendations to establish a national environmental public health tracking network. We present the results of a survey of public health and environmental practitioners to uncover state and local health tracking needs and priorities. We describe the steps that combined the findings from the state and local health tracking survey and a review of the state of the science on environmental impacts on health to identify priority health end points. Through an examination of national health and health care databases, we then describe trends and public health effects of those diseases that may be linked to the environment. Based on this analysis, respiratory diseases and neurologic diseases are recommended as priorities for tracking. Specific end points recommended for tracking include asthma and chronic respiratory diseases, and chronic neurodegenerative diseases such as multiple sclerosis. Based on trends in reported prevalence, consideration should also be given to developmental disabilities, reproductive disorders, and endocrine/metabolic disorders. Strengthening of current efforts to track cancer and birth defects should also be included as components of a nationwide health tracking network. Finally, we present the recommendations for environmental public health tracking. These recommendations provided the groundwork for the development of the Centers for Disease Control and Prevention's National Environmental Public Health Tracking Progam that now includes 21 states, three cities, and three academic centers throughout the nation. JF - Environmental Health Perspectives AU - Litt, Jill AU - Tran, Nga AU - Malecki, Kristen Chossek AU - Neff, Roni Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1414 EP - 1418 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Data collection KW - prevention KW - Environmental health KW - Asthma KW - Respiratory diseases KW - disease control KW - Cancer KW - Public health KW - Urban areas KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21417289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Identifying+Priority+Health+Conditions%2C+Environmental+Data%2C+and+Infrastructure+Needs%3A+A+Synopsis+of+the+Pew+Environmental+Health+Tracking+Project&rft.au=Litt%2C+Jill%3BTran%2C+Nga%3BMalecki%2C+Kristen+Chossek%3BNeff%2C+Roni&rft.aulast=Litt&rft.aufirst=Jill&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1414&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Data collection; prevention; Asthma; Environmental health; Respiratory diseases; disease control; Cancer; Urban areas; Public health ER - TY - JOUR T1 - Estimated Risk for Altered Fetal Growth Resulting from Exposure to Fine Particles during Pregnancy: An Epidemiologic Prospective Cohort Study in Poland AN - 21417240; 12429539 AB - The purpose of this study was to estimate exposure of pregnant women in Poland to fine particulate matter [less than or equal to 2.5 microm in diameter (PM 2.5)] and to assess its effect on the birth outcomes. The cohort consisted of 362 pregnant women who gave birth between 34 and 43 weeks of gestation. The enrollment included only nonsmoking women with singleton pregnancies, 18-35 years of age, who were free from chronic diseases such as diabetes and hypertension. PM 2.5 was measured by personal air monitoring over 48 hr during the second trimester of pregnancy. All assessed birth effects were adjusted in multiple linear regression models for potential confounding factors such as the size of mother (maternal height, prepregnancy weight), parity, sex of child, gestational age, season of birth, and self-reported environmental tobacco smoke (ETS). The regression model explained 35% of the variability in birth weight (beta = -200.8, p = 0.03), and both regression coefficients for PM 2.5 and birth length (beta = -1.44, p = 0.01) and head circumference (HC; beta = -0.73, p = 0.02) were significant as well. In all regression models, the effect of ETS was insignificant. Predicted reduction in birth weight at an increase of exposure from 10 to 50 microg/m3 was 140.3 g. The corresponding predicted reduction of birth length would be 1.0 cm, and of HC, 0.5 cm. The study provides new and convincing epidemiologic evidence that high personal exposure to fine particles is associated with adverse effects on the developing fetus. These results indicate the need to reduce ambient fine particulate concentrations. However, further research should establish possible biologic mechanisms explaining the observed relationship. JF - Environmental Health Perspectives AU - Jedrychowski, Wieslaw AU - Bendkowska, Ivona AU - Flak, Elzbieta AU - Penar, Agnieszka Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1398 EP - 1402 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Pollution monitoring KW - Age KW - parity KW - Passive smoking KW - Poland KW - hypertension KW - birth weight KW - Particulates KW - Side effects KW - Pregnancy KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21417240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Estimated+Risk+for+Altered+Fetal+Growth+Resulting+from+Exposure+to+Fine+Particles+during+Pregnancy%3A+An+Epidemiologic+Prospective+Cohort+Study+in+Poland&rft.au=Jedrychowski%2C+Wieslaw%3BBendkowska%2C+Ivona%3BFlak%2C+Elzbieta%3BPenar%2C+Agnieszka&rft.aulast=Jedrychowski&rft.aufirst=Wieslaw&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1398&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Pollution monitoring; parity; Age; Passive smoking; hypertension; birth weight; Particulates; Side effects; Pregnancy; Poland ER - TY - JOUR T1 - Statistical Methods for Linking Health, Exposure, and Hazards AN - 21406612; 12429535 AB - The Environmental Public Health Tracking Network (EPHTN) proposes to link environmental hazards and exposures to health outcomes. Statistical methods used in case-control and cohort studies to link health outcomes to individual exposure estimates are well developed. However, reliable exposure estimates for many contaminants are not available at the individual level. In these cases, exposure/hazard data are often aggregated over a geographic area, and ecologic models are used to relate health outcome and exposure/hazard. Ecologic models are not without limitations in interpretation. EPHTN data are characteristic of much information currently being collected--they are multivariate, with many predictors and response variables, often aggregated over geographic regions (small and large) and correlated in space and/or time. The methods to model trends in space and time, handle correlation structures in the data, estimate effects, test hypotheses, and predict future outcomes are relatively new and without extensive application in environmental public health. In this article we outline a tiered approach to data analysis for EPHTN and review the use of standard methods for relating exposure/hazards, disease mapping and clustering techniques, Bayesian approaches, Markov chain Monte Carlo methods for estimation of posterior parameters, and geostatistical methods. The advantages and limitations of these methods are discussed. JF - Environmental Health Perspectives AU - Mather, Frances Jean AU - White, LuAnn Ellis AU - Langlois, Elizabeth Cullen AU - Shorter, Charles Franklin Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1440 EP - 1445 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Monte Carlo simulation KW - Hazards KW - Data collection KW - Reviews KW - Mapping KW - environmental hazards KW - Public health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406612?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Statistical+Methods+for+Linking+Health%2C+Exposure%2C+and+Hazards&rft.au=Mather%2C+Frances+Jean%3BWhite%2C+LuAnn+Ellis%3BLanglois%2C+Elizabeth+Cullen%3BShorter%2C+Charles+Franklin&rft.aulast=Mather&rft.aufirst=Frances&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1440&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Hazards; Monte Carlo simulation; Data collection; Reviews; Mapping; environmental hazards; Public health ER - TY - JOUR T1 - Acute Infections and Environmental Exposure to Organochlorines in Inuit Infants from Nunavik AN - 21406140; 12429553 AB - The Inuit population of Nunavik (Canada) is exposed to immunotoxic organochlorines (OCs) mainly through the consumption of fish and marine mammal fat. We investigated the effect of perinatal exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) on the incidence of acute infections in Inuit infants. We reviewed the medical charts of a cohort of 199 Inuit infants during the first 12 months of life and evaluated the incidence rates of upper and lower respiratory tract infections (URTI and LRTIs, respectively), otitis media, and gastrointestinal (GI) infections. Maternal plasma during delivery and infant plasma at 7 months of age were sampled and assayed for PCBs and DDE. Compared to rates for infants in the first quartile of exposure to PCBs (least exposed), adjusted rate ratios for infants in higher quartiles ranged between 1.09 and 1.32 for URTIs, 0.99 and 1.39 for otitis, 1.52 and 1.89 for GI infections, and 1.16 and 1.68 for LRTIs during the first 6 months of follow-up. For all infections combined, the rate ratios ranged from 1.17 to 1.27. The effect size was similar for DDE exposure but was lower for the full 12-month follow-up. Globally, most rate ratios were 1.0, but few were statistically significant (p 0.05). No association was found when postnatal exposure was considered. These results show a possible association between prenatal exposure to OCs and acute infections early in life in this Inuit population. JF - Environmental Health Perspectives AU - Dallaire, Frederic AU - Dewailly, Eric AU - Muckle, Gina AU - Vezina, Carole Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1359 EP - 1365 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts KW - Organochlorine compounds KW - Chlorine compounds KW - Respiration KW - DDE KW - Outer continental shelf KW - Toxicity tests KW - Environmental factors KW - Insecticides KW - Nitrous oxide KW - Canada, Quebec, Nunavik KW - infection KW - Fish KW - PCB compounds KW - Pollution indicators KW - PCB KW - Metabolism KW - Infants KW - Respiratory tract KW - Q5 08504:Effects on organisms KW - ENA 12:Oceans & Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Acute+Infections+and+Environmental+Exposure+to+Organochlorines+in+Inuit+Infants+from+Nunavik&rft.au=Dallaire%2C+Frederic%3BDewailly%2C+Eric%3BMuckle%2C+Gina%3BVezina%2C+Carole&rft.aulast=Dallaire&rft.aufirst=Frederic&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1359&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Chlorine compounds; Respiration; DDE; Outer continental shelf; Environmental factors; Pollution indicators; Toxicity tests; Metabolism; PCB; Organochlorine compounds; Insecticides; Nitrous oxide; infection; Fish; PCB compounds; Respiratory tract; Infants; Canada, Quebec, Nunavik ER - TY - JOUR T1 - Tracking Pediatric Asthma: The Massachusetts Experience Using School Health Records AN - 21406071; 12429546 AB - The Massachusetts Department of Public Health, in collaboration with the U.S. Centers for Disease Control and Prevention Environmental Public Health Tracking Program, initiated a 3-year statewide project for the routine surveillance of asthma in children using school health records as the primary data source. School district nurse leaders received electronic data reporting forms requesting the number of children with asthma by grade and gender for schools serving grades kindergarten (K) through 8. Verification efforts from an earlier community-level study comparing a select number of school health records with primary care provider records demonstrated a high level of agreement (i.e., 95%). First-year surveillance targeted approximately one-half (n = 958 schools) of all Massachusetts's K-8 schools. About 78% of targeted school districts participated, and 70% of the targeted schools submitted complete asthma data. School nurse-reported asthma prevalence was as high as 30.8% for schools, with a mean of 9.2%. School-based asthma surveillance has been demonstrated to be a reliable and cost-effective method of tracking disease through use of an existing and enhanced reporting structure. JF - Environmental Health Perspectives AU - Knorr, Robert S AU - Condon, Suzanne K AU - Dwyer, Frances M AU - Hoffman, Danielle F Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1424 EP - 1427 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Data collection KW - USA, Massachusetts KW - schools KW - Economics KW - prevention KW - Asthma KW - Respiratory diseases KW - Children KW - Medical personnel KW - Public health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21406071?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Tracking+Pediatric+Asthma%3A+The+Massachusetts+Experience+Using+School+Health+Records&rft.au=Knorr%2C+Robert+S%3BCondon%2C+Suzanne+K%3BDwyer%2C+Frances+M%3BHoffman%2C+Danielle+F&rft.aulast=Knorr&rft.aufirst=Robert&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1424&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Data collection; schools; Economics; prevention; Asthma; Respiratory diseases; Children; Medical personnel; Public health; USA, Massachusetts ER - TY - JOUR T1 - Setting a New Syllabus: Environmental Health Science in the Classroom AN - 21399423; 12429554 AB - Environmental health is a subject that has only relatively recently become prominent in the social consciousness. Even as its significance becomes known, finding ways to integrate the subject into education for primary and secondary students is difficult because of federal testing requirements under the No Child Left Behind Act of 2001 and other demands placed on teachers. A number of efforts are under way, however, to provide teachers with resources to help them bring environment health into their classrooms. JF - Environmental Health Perspectives AU - Brown, Valerie J Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - A814 EP - A819 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Education KW - Environmental health KW - ENA 04:Environmental Education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21399423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Setting+a+New+Syllabus%3A+Environmental+Health+Science+in+the+Classroom&rft.au=Brown%2C+Valerie+J&rft.aulast=Brown&rft.aufirst=Valerie&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=A814&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Education; Environmental health ER - TY - JOUR T1 - Effect of Breast Milk Lead on Infant Blood Lead Levels at 1 Month of Age AN - 21399397; 12429549 AB - Nursing infants may be exposed to lead from breast milk, but relatively few data exist with which to evaluate and quantify this relationship. This route of exposure constitutes a potential infant hazard from mothers with current ongoing exposure to lead as well as from mothers who have been exposed previously due to the redistribution of cumulative maternal bone lead stores. We studied the relationship between maternal breast milk lead and infant blood lead levels among 255 mother-infant pairs exclusively or partially breast-feeding through 1 month of age in Mexico City. A rigorous, well-validated technique was used to collect, prepare, and analyze the samples of breast milk to minimize the potential for environmental contamination and maximize the percent recovery of lead. Umbilical cord and maternal blood lead were measured at delivery; 1 month after delivery (+/- 5 days) maternal blood, bone, and breast milk and infant blood lead levels were obtained. Levels of lead at 1 month postpartum were, for breast milk, 0.3-8.0 microg/L (mean +/- SD, 1.5 +/- 1.2); maternal blood lead, 2.9-29.9 microg/dL (mean +/- SD, 9.4 +/- 4.5); and infant blood lead, 1.0-23.1 microg/dL (mean +/- SD, 5.5 +/- 3.0). Infant blood lead at 1 month postpartum was significantly correlated with umbilical cord (Spearman correlation coefficient rS = 0.40, p 0.0001) and maternal (rS= 0.42, p 0.0001) blood lead at delivery and with maternal blood (rS= 0.67, p 0.0001), patella rS = 0.19, p = 0.004), and breast milk (rS = 0.32, p 0.0001) lead at 1 month postpartum. Adjusting for cord blood lead, infant weight change, and reported breast-feeding status, a difference of approximately 2 microg/L (ppb; from the midpoint of the lowest quartile to the midpoint of the highest quartile) breast milk lead was associated with a 0.82 microg/dL increase in blood lead for breast-feeding infants at 1 month of age. Breast milk lead accounted for 12% of the variance of infant blood lead levels, whereas maternal blood lead accounted for 30%. Although these levels of lead in breast milk were low, they clearly have a strong influence on infant blood lead levels over and above the influence of maternal blood lead. Additional information on the lead content of dietary alternatives and interactions with other nutritional factors should be considered. However, because human milk is the best and most complete nutritional source for young infants, breast-feeding should be encouraged because the absolute values of the effects are small within this range of lead concentrations. JF - Environmental Health Perspectives AU - Ettinger, Adrienne S AU - Tellez-Rojo, Martha Maria AU - Amarasiriwardena, Chitra AU - Bellinger, David Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1381 EP - 1385 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - Bone KW - Diets KW - Age KW - Mexico, Distrito Federal, Mexico City KW - Nutrition KW - Lead KW - Blood levels KW - Infants KW - breast milk KW - Urban areas KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21399397?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+of+Breast+Milk+Lead+on+Infant+Blood+Lead+Levels+at+1+Month+of+Age&rft.au=Ettinger%2C+Adrienne+S%3BTellez-Rojo%2C+Martha+Maria%3BAmarasiriwardena%2C+Chitra%3BBellinger%2C+David&rft.aulast=Ettinger&rft.aufirst=Adrienne&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1381&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Diets; Bone; Age; Nutrition; Lead; Urban areas; breast milk; Infants; Blood levels; Mexico, Distrito Federal, Mexico City ER - TY - JOUR T1 - The Fat of the Land: Do Agricultural Subsides Foster Poor Health? AN - 21399365; 12429544 AB - Since the 1920s, American farmers have received various forms of federal support in an effort to keep farmers farming and provide Americans with an affordable, stable food supply. Wheat, soybeans, and especially corn are currently the most highly subsidized crops; products made from these crops, including high-fructose corn syrup and hydrogenated fats, have flooded the market as cheap means for making foods tastier, though not healthier. Now critics are asking whether subsidies for these crops are actually driving the U.S. epidemic of obesity. JF - Environmental Health Perspectives AU - Fields, Scott Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - A820 EP - A823 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - wheat KW - Triticum aestivum KW - USA KW - Food supply KW - Economics KW - obesity KW - subsidies KW - Crops KW - corn KW - soybeans KW - ENA 06:Food & Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21399365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+occupational+hygiene&rft.atitle=Biological+monitoring+of+low+level+occupational+xylene+exposure+and+the+role+of+recent+exposure.&rft.au=Jacobson%2C+G+A%3BMcLean%2C+S&rft.aulast=Jacobson&rft.aufirst=G&rft.date=2003-06-01&rft.volume=47&rft.issue=4&rft.spage=331&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+occupational+hygiene&rft.issn=00034878&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - wheat; Food supply; Economics; obesity; subsidies; soybeans; corn; Crops; Triticum aestivum; USA ER - TY - JOUR T1 - The Association between Asthma and Allergic Symptoms in Children and Phthalates in House Dust: A Nested Case-Control Study AN - 21371599; 12429550 AB - Global phthalate ester production has increased from very low levels at the end of World War II to approximately 3.5 million metric tons/year. The aim of the present study was to investigate potential associations between persistent allergic symptoms in children, which have increased markedly in developed countries over the past three decades, and the concentration of phthalates in dust collected from their homes. This investigation is a case-control study nested within a cohort of 10,852 children. From the cohort, we selected 198 cases with persistent allergic symptoms and 202 controls without allergic symptoms. A clinical and a technical team investigated each child and her or his environment. We found higher median concentrations of butyl benzyl phthalate (BBzP) in dust among cases than among controls (0.15 vs. 0.12 mg/g dust). Analyzing the case group by symptoms showed that BBzP was associated with rhinitis (p = 0.001) and eczema (p = 0.001), whereas di(2-ethylhexyl) phthalate (DEHP) was associated with asthma (p = 0.022). Furthermore, dose-response relationships for these associations are supported by trend analyses. This study shows that phthalates, within the range of what is normally found in indoor environments, are associated with allergic symptoms in children. We believe that the different associations of symptoms for the three major phthalates-BBzP, DEHP, and di-n-butyl phthalate-can be explained by a combination of chemical physical properties and toxicologic potential. Given the phthalate exposures of children worldwide, the results from this study of Swedish children have global implications. JF - Environmental Health Perspectives AU - Bornehag, Carl-Gustaf AU - Sundell, Jan AU - Weschler, Charles J AU - Sigsgaard, Torben Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1393 EP - 1397 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - phthalates KW - House dust KW - skin diseases KW - Dose-response effects KW - Asthma KW - Respiratory diseases KW - Children KW - Esters KW - Dust KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21371599?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Association+between+Asthma+and+Allergic+Symptoms+in+Children+and+Phthalates+in+House+Dust%3A+A+Nested+Case-Control+Study&rft.au=Bornehag%2C+Carl-Gustaf%3BSundell%2C+Jan%3BWeschler%2C+Charles+J%3BSigsgaard%2C+Torben&rft.aulast=Bornehag&rft.aufirst=Carl-Gustaf&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1393&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - phthalates; House dust; skin diseases; Dose-response effects; Asthma; Respiratory diseases; Esters; Children; Dust ER - TY - JOUR T1 - Relative Fitness of Cry1A-Resistant and -Susceptible Helicoverpa Armigera (Lepidoptera: Noctuidae) on Conventional and Transgenic Cotton AN - 19836026; 6122712 AB - Glasshouse and laboratory experiments were conducted to evaluate the relative fitness of Cry1A-susceptible and laboratory-selected resistant strains of Helicoverpa armigera (Huebner). Life history parameters of H. armigera larvae feeding on young cotton plants showed a significant developmental delay of up to 7 d for the resistant strain compared with the susceptible strain on non-Bacillus thuringiensis (Bt) cotton. This fitness cost was not evident on artificial diet. There was no developmental delay in the F1 hybrid progeny from the reciprocal backcross of the resistant and susceptible strains, indicating that the fitness cost is recessive. In two cohorts tested, survival to pupation of resistant larvae on Bt cotton expressing Cry1Ac was 54 and 51% lower than on non-Bt cotton, whereas all susceptible and F1 larvae tested on Cry1Ac cotton were killed. Mortality of susceptible larvae occurred in the first or second instar, whereas the F1 larvae were able to develop to later instars before dying, demonstrating that resistance is incompletely recessive. The intrinsic rate of increase was reduced by >50% in the resistant strain on Cry1Ac cotton compared with the susceptible strain on non-Bt cotton. There was a significant reduction in the survival of postdiapausal adults from the resistant strain and the F1 strains, indicating that there is a nonrecessive overwintering cost associated with Cry1A resistance in H. armigera. JF - Journal of Economic Entomology AU - Bird, L J AU - Akhurst, R J AD - CSIRO Entomology, GPO Box 1700, Canberra ACT 2601, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1699 EP - 1709 PB - Entomological Society of America VL - 97 IS - 5 SN - 0022-0493, 0022-0493 KW - Noctuid moths KW - Microbiology Abstracts B: Bacteriology; Biotechnology and Bioengineering Abstracts; Entomology Abstracts KW - Fitness KW - Mortality KW - Feeding KW - Helicoverpa armigera KW - Cotton KW - Overwintering KW - Bacillus thuringiensis KW - Artificial diets KW - Survival KW - Pupation KW - Gossypium KW - Transgenic plants KW - Lepidoptera KW - Life history KW - Hybrids KW - Cry1Ac toxin KW - Progeny KW - Noctuidae KW - Toxicity testing KW - J 02410:Animal Diseases KW - W 30925:Genetic Engineering KW - Z 05183:Toxicology & resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19836026?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Economic+Entomology&rft.atitle=Relative+Fitness+of+Cry1A-Resistant+and+-Susceptible+Helicoverpa+Armigera+%28Lepidoptera%3A+Noctuidae%29+on+Conventional+and+Transgenic+Cotton&rft.au=Bird%2C+L+J%3BAkhurst%2C+R+J&rft.aulast=Bird&rft.aufirst=L&rft.date=2004-10-01&rft.volume=97&rft.issue=5&rft.spage=1699&rft.isbn=&rft.btitle=&rft.title=Journal+of+Economic+Entomology&rft.issn=00220493&rft_id=info:doi/10.1043%2F0022-0493%282004%290972.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0022-0493&volume=97&page=1699 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-05-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Fitness; Feeding; Mortality; Cotton; Overwintering; Artificial diets; Survival; Pupation; Transgenic plants; Life history; Hybrids; Cry1Ac toxin; Progeny; Toxicity testing; Helicoverpa armigera; Bacillus thuringiensis; Noctuidae; Gossypium; Lepidoptera DO - http://dx.doi.org/10.1043/0022-0493(2004)097<1699:RFOCAS>2.0.CO;2 ER - TY - JOUR T1 - Female Reproduct Ive Tract Abnormalities in European Hares (Lepus europaeus) in Australia AN - 19770641; 6133461 AB - Populations of European hare (Lepus europaeus) are in decline in Europe, and populations in Australia remain at low densities. Populations are sensitive to size of the breeding stock, which is influenced by fertility in the females. From 1996 to 1999, a total of 272 adult female hares from three Australian populations were dissected and their reproductive systems examined for abnormalities. Cystic endometrial hyperplasia was relatively common and often accompanied by hydrosalpinx. Extrauterine fetuses, neoplasms, pseudopregnancies, and resorptions also were found. However, although pseudopregnancies and resorptions were found in young adults (<12 mo) as well as older hares, conditions possibly causing infertility were almost always in older hares with prevalences up to 46.2%. Only hares with access to known sources of estrogens exhibited pathologic conditions, but sympatric European rabbits (Oryctolagus cuniculus) did not, which is consistent with known difference in responses between the corpora lutea of the two species to exogenous estrogen. Infertility at such a high prevalence could compound and extend the impact of years of low juvenile survival on recruitment. JF - Journal of Wildlife Diseases AU - Stott, Philip AU - Wight, Nicole AD - Department of Animal Science, University of Adelaide SA 5005, Australia and Pest Animal Control Cooperative Research Centre, GPO Box 284, Canberra ACT 2601, Australia, philip.stottadelaide.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 696 EP - 703 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com], [URL:http://www.allenpress.com] VL - 40 IS - 4 SN - 0090-3558, 0090-3558 KW - Ecology Abstracts KW - European hare KW - European rabbit KW - fertility KW - Lepus europaeus KW - Oryctolagus cuniculus KW - phytoestrogen KW - Infertility KW - Estrogens KW - Hyperplasia KW - Endometrium KW - Recruitment KW - Survival KW - Fetuses KW - Pseudopregnancy KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19770641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Diseases&rft.atitle=Female+Reproduct+Ive+Tract+Abnormalities+in+European+Hares+%28Lepus+europaeus%29+in+Australia&rft.au=Stott%2C+Philip%3BWight%2C+Nicole&rft.aulast=Stott&rft.aufirst=Philip&rft.date=2004-10-01&rft.volume=40&rft.issue=4&rft.spage=696&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Diseases&rft.issn=00903558&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Infertility; Endometrium; Hyperplasia; Estrogens; Recruitment; Survival; Fetuses; Pseudopregnancy; Oryctolagus cuniculus; Lepus europaeus ER - TY - JOUR T1 - Assessment of monophyly and taxon affinities within the polychaete clade Terebelliformia (Terebellida) AN - 19392646; 8660721 JF - Journal of the Marine Biological Association of the United Kingdom AU - Glasby, Christopher J AU - Hutchings, Patricia A AU - Hall, Kathryn AD - Museum and Art Gallery of the Northern Territory, GPO Box 4646, Darwin, NT 0801, Australia, chris.glasby@nt.gov.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 961 EP - 971 PB - Cambridge University Press, The Edinburgh Building, VL - 84 IS - 5 SN - 0025-3154, 0025-3154 KW - Ecology Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Ecology KW - Marine KW - Marine invertebrates KW - Terebellida KW - D 04040:Ecosystem and Ecology Studies KW - O 1030:Invertebrates KW - Q1 08243:Taxonomy and morphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19392646?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Marine+Biological+Association+of+the+United+Kingdom&rft.atitle=Assessment+of+monophyly+and+taxon+affinities+within+the+polychaete+clade+Terebelliformia+%28Terebellida%29&rft.au=Glasby%2C+Christopher+J%3BHutchings%2C+Patricia+A%3BHall%2C+Kathryn&rft.aulast=Glasby&rft.aufirst=Christopher&rft.date=2004-10-01&rft.volume=84&rft.issue=5&rft.spage=961&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Marine+Biological+Association+of+the+United+Kingdom&rft.issn=00253154&rft_id=info:doi/10.1017%2FS0025315404010252h LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Marine invertebrates; Ecology; Terebellida; Marine DO - http://dx.doi.org/10.1017/S0025315404010252h ER - TY - JOUR T1 - Creating a new conceptual framework: environment power and society AN - 18020715; 5985101 JF - Ecological Modelling AU - King, R J AD - Good Company Associates, Inc. 816 Congress Avenue, Suite 1100, Austin, TX 78701, USA, rking@goodcompanyassociates.com Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 159 EP - 162 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 178 IS - 1-2 SN - 0304-3800, 0304-3800 KW - Ecology Abstracts KW - Sociology KW - Mathematical models KW - D 04615:Ecology studies - general KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18020715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Creating+a+new+conceptual+framework%3A+environment+power+and+society&rft.au=King%2C+R+J&rft.aulast=King&rft.aufirst=R&rft.date=2004-10-01&rft.volume=178&rft.issue=1-2&rft.spage=159&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.12.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Sociology; Mathematical models DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.12.021 ER - TY - JOUR T1 - Standardized noise annoyance scales in Chinese, Korean and Vietnamese AN - 17880537; 6022109 AB - Internationally standardized annoyance scales are required in order to compare community responses to environmental noises measured in various linguistic regions. ICBEN Team 6 organized an international joint study to establish standardized noise annoyance scales and has developed scales and questions in nine linguistic regions. With the exception of Japan, all of these regions were Euro-American. Thus, it has been necessary to augment the original ICBEN study by utilizing the ICBEN method to construct noise annoyance scales for use in other Asian countries, because noise pollution is becoming an increasingly important environmental issue in these countries. Also, Asian data should be compared internationally with Euro-American data. The present study reports on the use of the ICBEN method to construct annoyance scales in Chinese, Korean and Vietnamese. JF - Journal of Sound and Vibration AU - Yano, T AU - Ma, H AD - Faculty of Engineering, Kumamoto University, Kumamoto 860-8555, Japan, yano@gpo.kumamoto-u.ac.jp Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 583 EP - 588 PB - Academic Press Ltd., 24-28 Oval Rd. London NW1 7DX UK, [mailto:apsubs@acad.com] VL - 277 IS - 3 SN - 0022-460X, 0022-460X KW - annoyance KW - linguistics KW - Chinese KW - Korean KW - Vietnamese KW - Pollution Abstracts KW - Psychology KW - Noise pollution KW - International standardization KW - P 7000:NOISE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880537?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Sound+and+Vibration&rft.atitle=Standardized+noise+annoyance+scales+in+Chinese%2C+Korean+and+Vietnamese&rft.au=Yano%2C+T%3BMa%2C+H&rft.aulast=Yano&rft.aufirst=T&rft.date=2004-10-01&rft.volume=277&rft.issue=3&rft.spage=583&rft.isbn=&rft.btitle=&rft.title=Journal+of+Sound+and+Vibration&rft.issn=0022460X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Psychology; Noise pollution; International standardization DO - http://dx.doi.org/10.1016/j.jsv.2004.03.020 ER - TY - JOUR T1 - Genetic relatedness of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated in south Asia AN - 17797508; 6031639 AB - OBJECTIVES: The aim of the present study was to determine the clonal relationships of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated from south Asia, and S. dysenteriae 1 strains associated with epidemics in 1978, 1984 and 1994. METHODS: The antimicrobial susceptibilities were examined by NCCLS methods. Molecular epidemiological characterization was performed by plasmid profiling, pulsed-field gel electrophoresis (PFGE) and mutation analysis of the quinolone resistance-determining region (QRDR) of gyrA by sequencing. RESULTS: Plasmid patterns of the current ciprofloxacin-resistant strains from India, Nepal and Bangladesh were very similar to those of the 1978, 1984 and 1994 epidemic isolates of S. dysenteriae 1, except for the presence of a new plasmid of -2.6 MDa, which was found in one recent ciprofloxacin-resistant strain isolated in Bangladesh. PFGE analysis showed that the ciprofloxacin- resistant strains isolated in Bangladesh, India and Nepal belonged to a PFGE type (type A), which was possibly related to that of the 1984 and 1994 clone of S. dysenteriae 1, but different from 1978 epidemic strains. The current ciprofloxacin-resistant strains belong to five subtypes (A3-A7), all of which were found in India, but in Bangladesh and Nepal, only A3 existed. Mutation analysis of the QRDR of gyrA revealed that amino acid substitutions at positions 83 and 87 of ciprofloxacin-resistant strains isolated in Bangladesh were similar to those of the strains isolated in Nepal, but different (at position 87) from ciprofloxacin-resistant strains isolated in India. CONCLUSIONS: PFGE and mutation analysis of gyrA showed differences between the current ciprofloxacin- resistant S. dysenteriae 1 strains isolated in south Asia and those associated with epidemics in 1978, 1984 and 1994. JF - Journal of Antimicrobial Chemotherapy AU - Talukder, Kaisar A AU - Khajanchi, Bijay K AU - Islam, MAminul AU - Dutta, Dilip K AU - Islam, Zhahirul AU - Safa, Ashrafus AU - Khan, G Y AU - Alam, Khorshed AU - Hossain, MA AU - Malla, Sarala AU - Niyogi, S K AU - Rahman, Mustafizur AU - Watanabe, Haruo AU - Balakrish Nair, G AU - Sack, David A AD - Enteric Microbiology Laboratory, Laboratory Sciences Division, ICDDR, B: Centre for Health and Population Research, GPO Box-128, Dhaka-1000, Bangladesh Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 730 EP - 734 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 54 IS - 4 SN - 0305-7453, 0305-7453 KW - Microbiology Abstracts B: Bacteriology KW - Ciprofloxacin KW - Amino acid substitution KW - Epidemics KW - Quinolones KW - Pulsed-field gel electrophoresis KW - Plasmids KW - Asia KW - Mutation KW - Antibiotic resistance KW - Shigella dysenteriae KW - J 02795:Antibiotic resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17797508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Antimicrobial+Chemotherapy&rft.atitle=Genetic+relatedness+of+ciprofloxacin-resistant+Shigella+dysenteriae+type+1+strains+isolated+in+south+Asia&rft.au=Talukder%2C+Kaisar+A%3BKhajanchi%2C+Bijay+K%3BIslam%2C+MAminul%3BDutta%2C+Dilip+K%3BIslam%2C+Zhahirul%3BSafa%2C+Ashrafus%3BKhan%2C+G+Y%3BAlam%2C+Khorshed%3BHossain%2C+MA%3BMalla%2C+Sarala%3BNiyogi%2C+S+K%3BRahman%2C+Mustafizur%3BWatanabe%2C+Haruo%3BBalakrish+Nair%2C+G%3BSack%2C+David+A&rft.aulast=Talukder&rft.aufirst=Kaisar&rft.date=2004-10-01&rft.volume=54&rft.issue=4&rft.spage=730&rft.isbn=&rft.btitle=&rft.title=Journal+of+Antimicrobial+Chemotherapy&rft.issn=03057453&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Shigella dysenteriae; Asia; Epidemics; Mutation; Plasmids; Antibiotic resistance; Ciprofloxacin; Quinolones; Pulsed-field gel electrophoresis; Amino acid substitution ER - TY - JOUR T1 - Centrifugation Assisted Agrobacterium tumefaciens-mediated Transformation (CAAT) of embryogenic cell suspensions of banana (Musa spp. Cavendish AAA and Lady finger AAB) AN - 17743325; 6106009 AB - Centrifugation-assisted Agrobacterium-mediated transformation (CAAT) protocol, developed using banana cultivars from two economically important genomic groups (AAA and AAB) of cultivated Musa, is described. This protocol resulted in 25-65 plants/50mg of settled cell volume of embryogenic suspension cells, depending upon the Agrobacterium strain used, and gave rise to hundreds of morphologically normal, transgenic plants in two banana cultivars from the two genomic groups. Development of a highly efficient Agrobacterium-mediated transformation protocol for a recalcitrant species like banana, especially the Cavendish group (AAA) cultivars, required the identification and optimisation of the factors affecting T-DNA delivery and subsequent plant regeneration. We used male-flower-derived embryogenic cell suspensions of two banana cultivars (Cavendish and Lady Finger) and Agrobacterium strains AGL1 and LBA4404, harbouring binary vectors carrying hpt (hygromycin phosphotransferase) and gusA ( beta -glucuronidase) or nptII (neomycin phosphotransferase) and a modified gfp (green fluorescent protein) gene in the T-DNA, to investigate and optimise T-DNA delivery and tissue culture variables. Factors evaluated included pre-induction of Agrobacterium, conditions and media used for inoculation and co-cultivation, and the presence of acetosyringone and Pluronic F68 in the co-cultivation media. One factor that led to a significant enhancement in transformation frequency was the introduction of a centrifugation step during co-cultivation. Post co-cultivation liquid-media wash and recovery step helped avoid Agrobacterium overgrowth on filters supporting suspension culture cells. Marker-gene expression and molecular analysis demonstrated that transgenes integrated stably into the banana genome. T-DNA:banana DNA boundary sequences were amplified and sequenced in order to study the integration profile. JF - Molecular Breeding AU - Khanna, H AU - Becker, D AU - Kleidon, J AU - Dale, J AD - Plant Biotechnology Program, Science Research Centre, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia, h.khanna@qut.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 239 EP - 252 PB - Kluwer Academic Publishers VL - 14 IS - 3 SN - 1380-3743, 1380-3743 KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Bioengineering Abstracts; Genetics Abstracts KW - Transformation KW - Nucleotide sequence KW - Transgenic plants KW - Gene expression KW - Agrobacterium tumefaciens KW - Centrifugation KW - Musa KW - T-DNA KW - Cell suspensions KW - Reporter gene KW - Morphology KW - W2 32065:Plants KW - G 07354:Dicotyledons (crops) KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17743325?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Remote+Sensing+of+Environment&rft.atitle=Decomposition+of+vegetation+cover+into+woody+and+herbaceous+components+using+AVHRR+NDVI+time+series&rft.au=Lu%2C+H%3BRaupach%2C+M+R%3BMcVicar%2C+T+R%3BBarrett%2C+D+J&rft.aulast=Lu&rft.aufirst=H&rft.date=2003-06-01&rft.volume=86&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Remote+Sensing+of+Environment&rft.issn=00344257&rft_id=info:doi/10.1016%2FS0034-4257%2803%2900054-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Musa; Agrobacterium tumefaciens; Cell suspensions; Transformation; Centrifugation; Morphology; Transgenic plants; Reporter gene; Gene expression; T-DNA; Nucleotide sequence DO - http://dx.doi.org/10.1023/B:MOLB.0000047771.34186.e8 ER - TY - JOUR T1 - Tribology Approach to the Engineering and Study of Articular Cartilage AN - 17703351; 6111523 AB - This study has been based on the assumption that articular motion is an important aspect of mechanotransduction in synovial joints. For this reason a new bioreactor concept, able to reproduce joint kinematics more closely, has been designed. The prototype consists of a rotating scaffold and/or cartilage pin, which is pressed onto an orthogonally rotating ball. By oscillating pin and ball in phase difference, elliptical displacement trajectories are generated that are similar to the motion paths occurring in vivo. Simultaneously, dynamic compression may be applied with a linear actuator, while two-step-motors generate the rotation of pin and ball. The whole apparatus is placed in an incubator. The control station is located outside. Preliminary investigations at the gene expression level demonstrated promising results. Compared with free-swelling control and/or simply compression-loaded samples, chondrocyte-seeded scaffolds as well as nasal cartilage explants exposed to interface motion both showed elevated levels of cartilage oligomeric matrix protein mRNA. The final design of the bioreactor will include four individual stations in line, which will facilitate the investigation of motion-initiated effects at the contacting surfaces in more detail. JF - Tissue Engineering AU - Wimmer, MA AU - Grad, S AU - Kaup, T AU - Haenni, M AU - Schneider, E AU - Gogolewski, S AU - Alini, M AD - Department of Orthopedic Surgery, Rush University Medical Center, 1653 W. Congress Pkwy, Suite 1417, Chicago, IL 60612, USA, markus_a_wimmer@rush.edu Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1436 EP - 1445 VL - 10 IS - 9-10 SN - 1076-3279, 1076-3279 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Cartilage oligomeric matrix protein KW - Kinematics KW - Tissue engineering KW - scaffolds KW - Compression KW - Joints KW - Gene expression KW - Bioreactors KW - Cartilage (articular) KW - Explants KW - Mechanotransduction KW - W 30965:Miscellaneous, Reviews KW - W3 33220:Cell culture KW - W4 110:Biomedical Materials & Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17703351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tissue+Engineering&rft.atitle=Tribology+Approach+to+the+Engineering+and+Study+of+Articular+Cartilage&rft.au=Wimmer%2C+MA%3BGrad%2C+S%3BKaup%2C+T%3BHaenni%2C+M%3BSchneider%2C+E%3BGogolewski%2C+S%3BAlini%2C+M&rft.aulast=Wimmer&rft.aufirst=MA&rft.date=2004-10-01&rft.volume=10&rft.issue=9-10&rft.spage=1436&rft.isbn=&rft.btitle=&rft.title=Tissue+Engineering&rft.issn=10763279&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - scaffolds; Bioreactors; Joints; Kinematics; Compression; Mechanotransduction; Gene expression; Cartilage (articular); Explants; Tissue engineering; Cartilage oligomeric matrix protein ER - TY - JOUR T1 - River patterns and their meaning AN - 17690571; 6046860 AB - Rivers are largely responsible for shaping the Earth's continental landscapes. River patterns, the spatial arrangements of channels in the landscape, are determined by slope and structure. At site and sector scale, channel morphology varies spatially and in time, but river patterns and drainage texture, or the frequency of stream lines per unit area, together determine the intricacy, or otherwise, of topography. Most river patterns evolve through natural selection. Slope induces the formation of such patterns as parallel, radial and distributary, while structure produces straight, angular, trellis and annular arrangements. Once established, patterns tend to persist. Nevertheless, at many sites the usual patterns have been disturbed and patterns that are anomalous in terms of slope and structure have been produced by diversion, tectonism, volcanism, glaciation, mass movements, and human activities; by antecedence, superimposition, inheritance or underprinting; by the persistence of deeply eroding rivers which encounter alien structures; and by climatic change. River patterns provide clues to underlying structure and to the chronology of events. They have also proved significant in the search for minerals. JF - Earth-Science Reviews AU - Twidale, C R AD - Geology and Geophysics, School of Earth and Environmental Sciences, The University of Adelaide, G.P.O. Box 498, Adelaide, South Australia 5005, Australia, rowl.twidale@adelaide.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 159 EP - 218 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 67 IS - 3-4 SN - 0012-8252, 0012-8252 KW - Meteorological & Geoastrophysical Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - Q2 02263:Topography and morphology KW - M2 556.5:Surface Water Hydrology (556.5) KW - SW 0835:Streamflow and runoff UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17690571?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Earth-Science+Reviews&rft.atitle=River+patterns+and+their+meaning&rft.au=Twidale%2C+C+R&rft.aulast=Twidale&rft.aufirst=C&rft.date=2004-10-01&rft.volume=67&rft.issue=3-4&rft.spage=159&rft.isbn=&rft.btitle=&rft.title=Earth-Science+Reviews&rft.issn=00128252&rft_id=info:doi/10.1016%2Fj.earscirev.2004.03.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.earscirev.2004.03.001 ER - TY - JOUR T1 - Effects Of Imposed Sterility On Movement Patterns Of Female Ricefield Rats AN - 17642864; 6456973 AB - Fertility control is used for the management of overabundant species. If sterilized individuals abandon their territories, fertile immigrants may invade and compromise fertility control. In southeast Asia, ricefield rats (Rattus argentiventer) can cause significant pre-harvest damage to lowland irrigated rice fields and may be a prime target for the use of fertility control. However, little is known about the behavioral response of ricefield rats to sterilization. We tested the effects of surgical and hormonal sterilization on movement patterns of female ricefield rats in rice fields in West Java, Indonesia. We found that surgically sterilized rats had the largest home ranges (1.8 plus or minus 0.1 ha), about twice the size of home ranges of hormonally sterilized rats and fertile rats. Hormonally sterilized rats tended to lose their territories-indicated by a high rate of burrow relocation-although hormonally sterilized, surgically sterilized, and fertile rats did not leave the ricefield system. We found no difference in survival rate and preference for refuge habitats between sterilized and fertile rats. Although changes in movement patterns after sterilization occurred, these changes are unlikely to affect the success of fertility control in ricefield rats negatively because sterilized rats remained in the ricefield system throughout the breeding period. JF - Journal of Wildlife Management AU - Jacob, J AU - Matulessy, J AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT, 2601, Australia, and Pest Animal Control Cooperative Research Centre, GPO Box 284, Canberra, ACT, 2601, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1138 EP - 1144 PB - The Wildlife Society VL - 68 IS - 4 SN - 0022-541X, 0022-541X KW - Ecology Abstracts KW - D 04700:Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17642864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Management&rft.atitle=Effects+Of+Imposed+Sterility+On+Movement+Patterns+Of+Female+Ricefield+Rats&rft.au=Jacob%2C+J%3BMatulessy%2C+J&rft.aulast=Jacob&rft.aufirst=J&rft.date=2004-10-01&rft.volume=68&rft.issue=4&rft.spage=1138&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Management&rft.issn=0022541X&rft_id=info:doi/10.2193%2F0022-541X%282004%290682.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0022-541X&volume=68&issue=4&page=1138 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-10-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.2193/0022-541X(2004)068[1138:EOISOM]2.0.CO;2 ER - TY - JOUR T1 - The Impact Of Sterilized Females On Enclosed Populations Of Ricefield Rats AN - 17638140; 6456972 AB - For the sustainable management of small mammals, fertility control may be used in the future. Little is known about what proportions of females need to be sterilized to achieve an impact on population size and what compensatory processes may act on the population level. We tested the impact of surgical sterilization of zero, 25, 50, and 75% of females on the population dynamics and demography of enclosed populations of ricefield rats (Rattus argentiventer) and damage to rice crop. Sterilizing 50% of female founders (6 of 12) decreased population size at the end of the breeding season by about 50%. We used a simulation model, based on the breeding biology of the ricefield rat in the field and in the control enclosures, to generate the expected dynamics of the enclosure populations. The results suggested that compensation occurred in the enclosures where 75% of female founders (9 of 12) had been sterilized. We detected a slight tendency for 50% higher numbers of recent uterine scars in fertile founder females in the 50% and 75% treatments versus 25% treatments and controls (P = 0.198). The primary demographic mechanism for compensation was higher survival of young rats in enclosures where 75% of females were sterilized. However, compensation only partially offset the decrease in population size. We found no conclusive evidence that the reproductive output of F sub(1) generation females was higher when large proportions of female founders were sterilized. Early in the breeding season, the per capita damage to rice plants in populations without sterilized ricefield rats was increased. Our results suggest that the sterilization of >50% of females in ricefield rat populations can reduce rat population growth and rat damage to rice crops. JF - Journal of Wildlife Management AU - Jacob, J AU - Aini herawati, N AU - Davis, SA AU - Singleton, G R AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT, 2601, Australia, and Pest Animal Control Cooperative Research Centre, GPO Box 284, Canberra, ACT, 2601, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1130 EP - 1137 PB - The Wildlife Society VL - 68 IS - 4 SN - 0022-541X, 0022-541X KW - Sustainability Science Abstracts; Ecology Abstracts KW - D 04700:Management KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17638140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Management&rft.atitle=The+Impact+Of+Sterilized+Females+On+Enclosed+Populations+Of+Ricefield+Rats&rft.au=Jacob%2C+J%3BAini+herawati%2C+N%3BDavis%2C+SA%3BSingleton%2C+G+R&rft.aulast=Jacob&rft.aufirst=J&rft.date=2004-10-01&rft.volume=68&rft.issue=4&rft.spage=1130&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Management&rft.issn=0022541X&rft_id=info:doi/10.2193%2F0022-541X%282004%290682.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0022-541X&volume=68&issue=4&page=1130 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.2193/0022-541X(2004)068[1130:TIOSFO]2.0.CO;2 ER - TY - JOUR T1 - Beyond Modelling: Linking Models with GIS for Flood Risk Management AN - 17604722; 6039266 AB - Spatially explicit hydrodynamic flood models can play an important role in natural hazard risk reduction. A key element of these models that make them suitable for risk reduction is the ability to provide time-series inundation information about the onset, duration and passing of a hazard event. Such information can be critical for landuse planning, for mapping evacuation egress routes, and for locating suitable emergency shelters to name only a few risk treatments. This research contends that a barrier to effective risk reduction is providing disaster managers with access to model results in a structured and flexible framework that allows consequences of different hazard scenarios to be assessed and mapped. To address these limitations, a framework has been developed that links a commercial relational database management system with a GIS-based decision support system. The framework utilises industry standard data exchange protocols and results in efficient time-series hazard data management. A case study based in Cairns, in far-north coastal Australia is presented to illustrate how the system has been developed. Results show that the framework reduces data volumes significantly, while making pre-run modelled inundation results rapidly accessible to disaster managers. Of note is the ability of the framework to present results in terms of risk to buildings, roads and other spatial features in urban regions, and to provide answers to relatively complex risk questions. JF - Natural Hazards AU - Zerger, A AU - Wealands, S AD - CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT 2601, Australia, andre.zerger@csiro.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 191 EP - 208 PB - Kluwer Academic Publishers VL - 33 IS - 2 SN - 0921-030X, 0921-030X KW - Meteorological & Geoastrophysical Abstracts; Health & Safety Science Abstracts; Water Resources Abstracts; Risk Abstracts KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - SW 2060:Effects on water of human nonwater activities KW - R2 23030:Natural hazards KW - M2 556.16:Runoff (556.16) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17604722?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Natural+Hazards&rft.atitle=Beyond+Modelling%3A+Linking+Models+with+GIS+for+Flood+Risk+Management&rft.au=Zerger%2C+A%3BWealands%2C+S&rft.aulast=Zerger&rft.aufirst=A&rft.date=2004-10-01&rft.volume=33&rft.issue=2&rft.spage=191&rft.isbn=&rft.btitle=&rft.title=Natural+Hazards&rft.issn=0921030X&rft_id=info:doi/10.1023%2FB%3ANHAZ.0000037040.72866.92 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1023/B:NHAZ.0000037040.72866.92 ER - TY - JOUR T1 - Proclivity and effectiveness in gall defence by soldiers in five species of gall-inducing thrips: benefits of morphological caste dimorphism in two species (Kladothrips intermedius and K. habrus) AN - 17505925; 6282874 AB - The essence of eusociality is a trade-off between producing one's own offspring and helping collateral kin via such activities as defence, foraging and brood rearing. This trade-off often involves morphological differences between 'helper' and 'reproductive' castes, but the advantages, correlates and phylogenetic context of morphological caste differentiation have seldom been analysed. Six species of Australian gall-inducing thrips on Acacia show morphological polymorphism. One morph, referred to as a soldier, has reduced wings and antennae but greatly enlarged fore-femora, which are thought to be adaptations for gall defence. The other, dispersing morph, has fully developed wings and relatively slight fore-femora. Here, we quantify the defensive behaviour of soldier morphs, and compare soldier and foundresses, using behavioural assays designed to measure proclivity to attack kleptoparasites (specialised invaders in the genus Koptothrips) and effectiveness in killing them. In all five species investigated, soldiers were able to kill Koptothrips. Moreover, the effectiveness of soldiers was relatively high in the more-derived species in the phylogeny of the clade, Kladothrips intermedius, K. habrus and K. waterhousei. Soldiers of K. intermedius and K. habrus also killed kleptoparasites more effectively than did foundresses, and K. habrus soldiers exhibited higher proclivity to attack than did foundresses. Data from naturally invaded galls demonstrate that soldiers in the field do kill Koptothrips, and vice versa. These results show that soldiers of Australian gall thrips are motivated and effective for gall defence. JF - Behavioral Ecology and Sociobiology AU - Perry, S P AU - Chapman, T W AU - Schwarz, M P AU - Crespi, B J AD - Flinders University, GPO Box 2100, SA 5001, Adelaide, Australia, simp0082@flinders.edu.au Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 602 EP - 610 PB - Springer-Verlag (Berlin), Heidelberger Platz 3 Berlin 14197 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 56 IS - 6 SN - 0340-5443, 0340-5443 KW - Animal Behavior Abstracts; Ecology Abstracts; Entomology Abstracts KW - Canker KW - Castes KW - Acacia KW - Caste differentiation KW - Dimorphism KW - Phylogeny KW - Wings KW - Brood rearing KW - Soldiers KW - D 04659:Insects KW - Z 05198:Defense & offense KW - Y 25503:Insects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17505925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Behavioral+Ecology+and+Sociobiology&rft.atitle=Proclivity+and+effectiveness+in+gall+defence+by+soldiers+in+five+species+of+gall-inducing+thrips%3A+benefits+of+morphological+caste+dimorphism+in+two+species+%28Kladothrips+intermedius+and+K.+habrus%29&rft.au=Perry%2C+S+P%3BChapman%2C+T+W%3BSchwarz%2C+M+P%3BCrespi%2C+B+J&rft.aulast=Perry&rft.aufirst=S&rft.date=2004-10-01&rft.volume=56&rft.issue=6&rft.spage=602&rft.isbn=&rft.btitle=&rft.title=Behavioral+Ecology+and+Sociobiology&rft.issn=03405443&rft_id=info:doi/10.1007%2Fs00265-004-0811-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Acacia; Soldiers; Canker; Castes; Wings; Brood rearing; Caste differentiation; Dimorphism; Phylogeny DO - http://dx.doi.org/10.1007/s00265-004-0811-8 ER - TY - JOUR T1 - Drug Delivery Across the Blood-Brain Barrier AN - 17437814; 6538398 AB - The brain is protected and isolated from the general circulation by a highly efficient blood-brain barrier. This is characterised by relatively impermeable endothelial cells with tight junctions, enzymatic activity and active efflux transport systems. Consequently the blood-brain barrier is designed to permit selective transport of molecules that are essential for brain function. This creates a considerable challenge for the treatment of central nervous system diseases requiring therapeutic levels of drug to enter the brain. Some small lipophilic drugs diffuse across the blood-brain barriersufficiently well to be efficacious. However, many potentially useful drugs are excluded. This review provides an insight into the current research into technologies to target small molecules, peptides and proteins to the brain. A brief review of the nature of the blood-brain barrier and its transport mechanisms is provided. Strategies to target and improve transport across the blood-brain barrier include the prodrug-lipidisation approach, sequential metabolism chemical delivery systems, drug-vectors, liposomes and nanoparticles. Included is the discussion of techniques to minimise clearance from the circulation by the reticuloendothelial system in order to extend circulation residence time and optimise the opportunity for interaction between the drug delivery system and the blood-brain barrier. JF - Current Drug Delivery AU - Chen, Y AU - Dalwadi, G AU - Benson, HAE AD - Western Australian Biomedical Research Institute, School of Pharmacy, Curtin University of Technology, GPO Box U1987, Perth, Western Australia 6845, Australia Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 361 EP - 376 VL - 1 IS - 4 SN - 1567-2018, 1567-2018 KW - Biotechnology and Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Endothelial cells KW - Drug delivery KW - Tight junctions KW - Blood-brain barrier KW - Reviews KW - Central nervous system diseases KW - Brain KW - Reticuloendothelial system KW - Liposomes KW - nanoparticles KW - Lipophilic KW - W3 33388:Drug delivery vehicles (liposomes, cochleates, microspheres) KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17437814?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+Drug+Delivery&rft.atitle=Drug+Delivery+Across+the+Blood-Brain+Barrier&rft.au=Chen%2C+Y%3BDalwadi%2C+G%3BBenson%2C+HAE&rft.aulast=Chen&rft.aufirst=Y&rft.date=2004-10-01&rft.volume=1&rft.issue=4&rft.spage=361&rft.isbn=&rft.btitle=&rft.title=Current+Drug+Delivery&rft.issn=15672018&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Blood-brain barrier; Brain; Drug delivery; Reviews; Central nervous system diseases; nanoparticles; Endothelial cells; Lipophilic; Liposomes; Tight junctions; Reticuloendothelial system ER - TY - JOUR T1 - Environmental Protection Issues in the 108th Congress AN - 14722005; 10673298 AB - Key environmental protection issues that are receiving attention in the 108th Congress are surveyed. At the start of the second session, Congress completed consideration of a consolidated appropriations Act which provides $8.27 billion for EPA in FY2004. The Administration had requested $7.79 billion, $577 million less than the FY2004 appropriations. The 108th Congress has taken, but in most cases not completed, action on legislation to address leaking underground storage tanks that may contaminate water supplies, security issues related to wastewater treatment and chemical facilities, environmental issues in comprehensive energy legislation, and expanding authority for an EPA ombudsman. JF - US Congressional Research Service Report IB10115 AU - Fletcher, Susan AU - Isler, Margaret Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - SUPERFUND KW - LEGISLATION, FEDERAL KW - EPA, FEDERAL KW - HAZARDOUS WASTE MANAGEMENT KW - CLEAN AIR ACT AMENDMENTS 90 KW - CLEAN WATER ACT KW - UNDERGROUND FUEL STORAGE KW - POLLUTION CONTROL FINANCING KW - ENV PROBLEMS, GENERAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14722005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10115&rft.atitle=Environmental+Protection+Issues+in+the+108th+Congress&rft.au=Fletcher%2C+Susan%3BIsler%2C+Margaret&rft.aulast=Fletcher&rft.aufirst=Susan&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10115&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SUPERFUND; LEGISLATION, FEDERAL; UNDERGROUND FUEL STORAGE; HAZARDOUS WASTE MANAGEMENT; EPA, FEDERAL; CLEAN AIR ACT AMENDMENTS 90; CLEAN WATER ACT; POLLUTION CONTROL FINANCING; ENV PROBLEMS, GENERAL ER - TY - JOUR T1 - Western Water Resource Issues AN - 14721768; 10673302 AB - Pressures on water resources are mounting in the western US, where agricultural needs are often in direct conflict with urban needs as well as with water demand for threatened and endangered species and recreation. The 108th Congress is considering many western water resource issues, and new developments involving California's allocation of Colorado River water has spurred additional oversight of related topics, such as progress in restoring the Salton Sea. In September 2004, the Senate passed a bill to authorize implementation of the CALFED Bay-Delta Program, a federal and state effort to coordinate water management and ecosystem restoration activities at the confluence of the Sacramento and San Joaquin Rivers and San Francisco Bay. JF - US Congressional Research Service Report IB10019 AU - Cody, Betsy A AU - Sheikh, Pervaze A Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - MULTIPLE USE, WATER KW - LEGISLATION, FEDERAL KW - WATER SUPPLY KW - INTERBASIN WATER TRANSFER KW - RIVER BASINS KW - WATER RESOURCES MANAGEMENT KW - WATER LAW KW - IRRIGATION KW - ENV RESTORATION KW - URBAN WATER RESOURCES KW - UNITED STATES WEST KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14721768?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Materials+Science%3A+Materials+in+Medicine&rft.atitle=Calcium+phosphate+nucleation+on+surface-modified+PTFE+membranes&rft.au=GrOendahl%2C+Lisbeth%3BCardona%2C+Francisco%3BChiem%2C+Khang%3BWentrup-Byrne%2C+Edeline%3BBostrom%2C+Thor&rft.aulast=GrOendahl&rft.aufirst=Lisbeth&rft.date=2003-06-01&rft.volume=14&rft.issue=6&rft.spage=503&rft.isbn=&rft.btitle=&rft.title=Journal+of+Materials+Science%3A+Materials+in+Medicine&rft.issn=09574530&rft_id=info:doi/10.1023%2FA%3A1023403929496 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV RESTORATION; MULTIPLE USE, WATER; LEGISLATION, FEDERAL; URBAN WATER RESOURCES; INTERBASIN WATER TRANSFER; WATER SUPPLY; RIVER BASINS; WATER RESOURCES MANAGEMENT; UNITED STATES WEST; IRRIGATION; WATER LAW ER - TY - JOUR T1 - Clean Air Act Issues in the 108th Congress AN - 14719575; 10673301 AB - Prominent air quality issues of interest in the 108th Congress are surveyed. Major debate has focused on coal-fired power plant emissions and EPA's controversial proposed standards for mercury, sulfur dioxide, and nitrogen oxides emissions from these plants. Legislation has also been submitted to replace numerous Clean Air Act requirements with a national cap and trade program for these pollutants. The Senate approved a bill directing NAS to conduct a study of changes proposed by EPA to streamline New Source Review Requirements. Congressional attention to emission standards for small engines, transportation conformity, Clear Skies legislation, and designation of nonattainment areas for new particulate matter and 8-h ozone standards is also noted. JF - US Congressional Research Service Report IB10107 AU - McCarthy, James E Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - POWER PLANTS, COAL FIRED KW - AIR QUALITY PROGRAMS KW - EMISSION CONTROL STANDARDS KW - SULFUR DIOXIDE KW - LEGISLATION, FEDERAL KW - EPA, FEDERAL KW - AIR QUALITY STANDARDS, SOURCE KW - PARTICULATES KW - OZONE KW - NITROGEN OXIDES KW - POWER PLANT EMISSION CONTROL KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14719575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10107&rft.atitle=Clean+Air+Act+Issues+in+the+108th+Congress&rft.au=McCarthy%2C+James+E&rft.aulast=McCarthy&rft.aufirst=James&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10107&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; POWER PLANTS, COAL FIRED; AIR QUALITY PROGRAMS; LEGISLATION, FEDERAL; NITROGEN OXIDES; EMISSION CONTROL STANDARDS; AIR QUALITY STANDARDS, SOURCE; EPA, FEDERAL; POWER PLANT EMISSION CONTROL; MERCURY; OZONE; PARTICULATES ER - TY - JOUR T1 - Clean Water Act Issues in the 108th Congress AN - 14719448; 10673300 AB - In 2002, Congressional committees approved bills to reauthorize wastewater infrastructure funding under the Clean Water Act, but no further action occurred. This issue has also received attention in the 108th Congress. In October 2004, the Senate Environment and Public Works Committee reported legislation to authorize $20 billion in funding for clean water infrastructure. While prospects for further action during the 108th Congress are uncertain, several issues under the Act could be the focus of debate, including revisions to the total maximum daily load program, wetlands provisions, and pollution from confined animal feeding operations. JF - US Congressional Research Service Report IB10108 AU - Copeland, Claudia Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - LEGISLATION, FEDERAL KW - LIVESTOCK FEEDLOT RUNOFF KW - CLEAN WATER ACT KW - WATER POLLUTION CONTROL FINANCING KW - WASTEWATER TREATMENT KW - WATER QUALITY STANDARDS KW - WETLANDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14719448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10108&rft.atitle=Clean+Water+Act+Issues+in+the+108th+Congress&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10108&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - WATER POLLUTION CONTROL FINANCING; WASTEWATER TREATMENT; LEGISLATION, FEDERAL; LIVESTOCK FEEDLOT RUNOFF; CLEAN WATER ACT; WATER QUALITY STANDARDS; WETLANDS ER - TY - JOUR T1 - Water Quality: Implementing the Clean Water Act AN - 14718062; 10673297 AB - Recent developments in the implementation of the Clean Water Act Amendments of 1987 are surveyed. Impacts and implementation of requirements under current law for states to develop total maximum daily loads to restore pollution-affected waters are covered, as is progress in implementing nonpoint pollution management provisions. States are devising management policies describing methods that will be applied to reduce such pollution, which may be responsible for as much as 50% of remaining water quality problems in the US. Implementation of these measures is hindered by limited resources, and EPA has adopted program guidance intended to afford states more flexibility and to speed up progress in this arena. JF - US Congressional Research Service Report IB89102 AU - Copeland, Claudia Y1 - 2004/10// PY - 2004 DA - Oct 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - CLEAN WATER ACT AMENDMENTS 87 KW - LAW ENFORCEMENT, FEDERAL KW - STATE AND LOCAL ENV PROGRAMS KW - WATER POLLUTION CONTROL FINANCING KW - NONPOINT SOURCE POLLUTION KW - WATER QUALITY STANDARDS KW - WETLANDS KW - WATER QUALITY PROGRAMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718062?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB89102&rft.atitle=Water+Quality%3A+Implementing+the+Clean+Water+Act&rft.au=Copeland%2C+Claudia&rft.aulast=Copeland&rft.aufirst=Claudia&rft.date=2004-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB89102&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - WATER POLLUTION CONTROL FINANCING; STATE AND LOCAL ENV PROGRAMS; CLEAN WATER ACT AMENDMENTS 87; NONPOINT SOURCE POLLUTION; LAW ENFORCEMENT, FEDERAL; WATER QUALITY STANDARDS; WETLANDS; WATER QUALITY PROGRAMS ER - TY - JOUR T1 - Wisconsin's Environmental Public Health Tracking Network: Information Systems Design for Childhood Cancer Surveillance AN - 14710422; 10670453 AB - An information technology platform is described, which is in development to support environmental public-health tracking in Wisconsin. Called Wisconsin's Public Health Information Network, it is aimed at rapid, state-of-the-art technology transfer from the university to government, business, and all citizens of the state. Described specifically is the childhood cancer surveillance, which utilizes statewide health and environmental monitoring information and nationally available environmental and demographic datasets. System specifications required the support of two surveillance tracks-hypothesis generation and hypothesis testing-to provide a more complete view of environmental disease risk. JF - Environmental Health Perspectives AU - Hanrahan, Lawrence P AU - Anderson, Henry A AU - Busby, Brian AU - Bekkedal, Marni AU - Sieger, Thomas AU - Stephenson, Laura AU - Knobeloch, Lynda Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1434 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - PUBLIC HEALTH KW - INFORMATION SYSTEMS, ENV KW - MEDICAL SURVEILLANCE KW - WISCONSIN KW - PATHOLOGY, CHILDREN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Chemical+Ecology&rft.atitle=Effects+of+two+plant+secondary+metabolites%2C+cineole+and+gallic+acid%2C+on+nightly+feeding+patterns+of+the+common+brushtail+possum&rft.au=Wiggins%2C+N+L%3BMcArthur%2C+C%3BMcLean%2C+S%3BBoyle%2C+R&rft.aulast=Wiggins&rft.aufirst=N&rft.date=2003-06-01&rft.volume=29&rft.issue=6&rft.spage=1447&rft.isbn=&rft.btitle=&rft.title=Journal+of+Chemical+Ecology&rft.issn=00980331&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - INFORMATION SYSTEMS, ENV; CANCER RISK; MEDICAL SURVEILLANCE; PATHOLOGY, CHILDREN; WISCONSIN; PUBLIC HEALTH ER - TY - JOUR T1 - Arsenic on the Hands of Children After Playing in Playgrounds AN - 14709552; 10670442 AB - At 16 playgrounds in Edmonton, AB, Canada, the amount of arsenic on the hands of children in contact with chromated copper arsenate (CCA)-treated wood structures and sand was quantified. Half of the playgrounds were constructed with CCA-treated wood, and the other were used as controls. After play, the children's hands were washed, and the As concentration on the hands and in the sand was measured in the washing. No significant difference was found between CCA and non-CCA playgrounds in terms of As concentrations in the sand/soil samples, and the As concentrations in all samples were below the Canadian guideline value of 12 mg/kg. A difference was found in the As concentration in the washings of children's hands, with the total amount of As and As in the sand collected from children's hands significantly higher for the CCA group than for the non-CCA group. The difference was dominated by the soluble As in the hand-washing water, which was approximately fivefold higher in the CCA group than in the non-CCA group. The maximum among of As on the children's hands, however, was less than 4 mu g, which is lower than the average daily intake of As from water and food. JF - Environmental Health Perspectives AU - Kwon, Elena AU - Zhang, Hongquan AU - Wang, Zongwen AU - Jhangri, Gian S AU - Lu, Xiufen AU - Fok, Nelson AU - Gabos, Stephan Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1375 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - ALBERTA KW - ARSENIC KW - RECREATION, OUTDOOR, LAND KW - SOIL ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Arsenic+on+the+Hands+of+Children+After+Playing+in+Playgrounds&rft.au=Kwon%2C+Elena%3BZhang%2C+Hongquan%3BWang%2C+Zongwen%3BJhangri%2C+Gian+S%3BLu%2C+Xiufen%3BFok%2C+Nelson%3BGabos%2C+Stephan&rft.aulast=Kwon&rft.aufirst=Elena&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1375&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; ALBERTA; RECREATION, OUTDOOR, LAND; ARSENIC; SOIL ANALYSIS ER - TY - JOUR T1 - Drinking-Water Nitrate, Methemoglobinemia, and Global Burden of Disease: a Discussion AN - 14709094; 10670441 AB - The Global Burden of Disease project, conducted under the auspices of WHO, is attempting to quantify and compare the level of illness at both world and regional levels. One such disease is nitrate-related drinking-water methemoglobinemia, which is a disease mainly of young children. Methemoglobin is formed when nitrite oxidizes the ferrous iron in hemoglobin to the ferric form, and the condition is characterized by cyanosis, stupor, and cerebral anoxia, as methemoglobin cannot bind oxygen. A review is presented of the role of nitrates in the causation of methemoglobinemia, citing the limited data that have been published. A number of authors, however, are questioning the simple association between NO sub(3) and infant methemoglobinemia, proposing instead that NO sub(3) is a cofactor in one of several causes of the disease. JF - Environmental Health Perspectives AU - Fewtrell, Lorna Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1371 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DISEASES AND DISORDERS KW - NITRATES KW - WATER, DRINKING KW - METHEMOGLOBINEMIA KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709094?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Drinking-Water+Nitrate%2C+Methemoglobinemia%2C+and+Global+Burden+of+Disease%3A+a+Discussion&rft.au=Fewtrell%2C+Lorna&rft.aulast=Fewtrell&rft.aufirst=Lorna&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1371&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; NITRATES; METHEMOGLOBINEMIA; WATER, DRINKING; LITERATURE SURVEYS ER - TY - JOUR T1 - Outdoor, Indoor, and Personal Exposure to VOCs in Children AN - 14705173; 10670444 AB - As part of the School Health Initiative: Environment, Learning, and Disease Study in Minneapolis, MN, the distribution of exposures to common VOCs was measured in personal air and in three primary microenvironments where children spend most of their time. Measurements were made outdoors and indoors at school and home for an ethnically and racially diverse sample of inner-city children. For most of the compounds, indoor residences had the highest VOC concentrations, followed by personal air, while outdoor and school microenvironments were relatively small contributors to personal exposure. Personal air concentrations were slightly lower than indoor home concentrations for all compounds except p-dichlorobenzene. In the home, adult tobacco use was associated with elevated styrene and benzene personal exposures, and use of cleaning supplies was associated with higher d-limonene, p-dichlorobenzene, and trichloroethylene personal exposures. African Americans had higher chloroform exposures; Hispanics had higher p-dichlorobenzene and beta -pinene exposures; Somalis had higher beta -pinene exposures; and Southeast Asians had higher d-limonene and p-dichlorobenzene exposures. JF - Environmental Health Perspectives AU - Adgate, John L AU - Church, Timothy R AU - Ryan, Andrew D AU - Ramachandran, Gurumurthy AU - Fredrickson, Ann L AU - Stock, Thomas H AU - Morandi, Maria T Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1386 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SCHOOLS KW - VOLATILE ORGANIC COMPOUNDS KW - URBAN ATMOSPHERE KW - AIR POLLUTION, INDOOR KW - RACIAL COMPARISONS KW - INNER CITY KW - MINNESOTA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Outdoor%2C+Indoor%2C+and+Personal+Exposure+to+VOCs+in+Children&rft.au=Adgate%2C+John+L%3BChurch%2C+Timothy+R%3BRyan%2C+Andrew+D%3BRamachandran%2C+Gurumurthy%3BFredrickson%2C+Ann+L%3BStock%2C+Thomas+H%3BMorandi%2C+Maria+T&rft.aulast=Adgate&rft.aufirst=John&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1386&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 43 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SCHOOLS; AIR POLLUTION, INDOOR; INNER CITY; RACIAL COMPARISONS; MINNESOTA; VOLATILE ORGANIC COMPOUNDS; URBAN ATMOSPHERE ER - TY - JOUR T1 - National Environmental Public Health Tracking Program: Bridging the Information Gap AN - 14705163; 10670448 JF - Environmental Health Perspectives AU - MaGeehin, Michael A AU - Qualters, Judith R AU - Niskar, Amanda Sue Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1409 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - INFORMATION SYSTEMS, ENV KW - MEDICAL SURVEILLANCE KW - PUBLIC HEALTH KW - MONITORING, ENV KW - ENV ACTION, FEDERAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=National+Environmental+Public+Health+Tracking+Program%3A+Bridging+the+Information+Gap&rft.au=MaGeehin%2C+Michael+A%3BQualters%2C+Judith+R%3BNiskar%2C+Amanda+Sue&rft.aulast=MaGeehin&rft.aufirst=Michael&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1409&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - INFORMATION SYSTEMS, ENV; MEDICAL SURVEILLANCE; MONITORING, ENV; PUBLIC HEALTH; ENV ACTION, FEDERAL ER - TY - JOUR T1 - Application of Benzo(a)pyrene and Coal Tar Tumor DoseResponse Data to a Modified Benchmark Dose Method of Guideline Development AN - 14705112; 10670437 AB - The benchmark dose (BMD) method uses conventional mathematical models to obtain doseresponse curves. In Australia, a modified BMD method has been developed that combines toxicologic doseresponse data and conventional mathematical models to generate doseresponse curves, which avoids the conservatism of other BMD models. In this study, the modified BMD method was used to construct tumor doseresponse curves for benzo(a)pyrene (BaP) using data from a recently published 2-yr feeding study on female B6C3F1 mice. The bioassay also examined the tumor response of the mice to two coal-tar mixtures. Results suggested a BaP soil guideline value of 5 ppm, which would be a significant departure from the current guideline of 1 ppm based on consideration of proportionality of dietary BaP and related cancer risk derived from the EPA conservative linearized multistage model. JF - Environmental Health Perspectives AU - Fitzgerald, DJames AU - Robinson, Neville I AU - Pester, Beverly A Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1341 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - SOIL CONTAMINATION KW - TUMORIGENIC AGENTS KW - COAL TARS KW - DOSE RESPONSE PROFILES KW - MATHEMATIC MODELS, CARCINOGENESIS KW - BENZO-A-PYRENE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705112?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Application+of+Benzo%28a%29pyrene+and+Coal+Tar+Tumor+Dose%26lt%3BND%26gt%3BResponse+Data+to+a+Modified+Benchmark+Dose+Method+of+Guideline+Development&rft.au=Fitzgerald%2C+DJames%3BRobinson%2C+Neville+I%3BPester%2C+Beverly+A&rft.aulast=Fitzgerald&rft.aufirst=DJames&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1341&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - COAL TARS; CANCER RISK; DOSE RESPONSE PROFILES; SOIL CONTAMINATION; MATHEMATIC MODELS, CARCINOGENESIS; BENZO-A-PYRENE; TUMORIGENIC AGENTS ER - TY - JOUR T1 - Paternal Occupational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Birth Outcomes of Offspring: Birth Weight, Preterm Delivery, and Birth Defects AN - 14704828; 10670447 AB - Pregnancy outcomes were examined among wives of male chemical workers who were exposed highly to chemicals contaminated with TCDD and among wives of nonexposed neighborhood referents in New Jersey and Missouri. Dates of employment in TCDD-related processes defined the exposure period, and pregnancies conceived after the father's first date of exposure were considered exposed. A pharmacokinetic model was used to estimate the worker's serum TCDD concentration at the time of conception. The pregnancy outcomes analyzed were birth weight, preterm delivery, and birth defects. No causal relationship was found between low birth weight and high paternal TCDD exposure. Rather, a positive association was observed between paternal dioxin exposure and birth weight. The proportion of preterm births was low in the study population, and it was lower among exposed births. A low incidence of birth defects was reported among the entire study population. JF - Environmental Health Perspectives AU - Lawson, Christina C AU - Schnorr, Teresa M AU - Whelan, Elizabeth A AU - Deddens, James A AU - Dankovic, David A AU - Piacitelli, Laurie A AU - Sweeney, Marie H Y1 - 2004/10// PY - 2004 DA - Oct 2004 SP - 1403 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 14 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - REPRODUCTION, HUMAN KW - BIRTH DEFECTS, HUMAN KW - TETRACHLORODIBENZODIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Paternal+Occupational+Exposure+to+2%2C3%2C7%2C8-Tetrachlorodibenzo-p-Dioxin+and+Birth+Outcomes+of+Offspring%3A+Birth+Weight%2C+Preterm+Delivery%2C+and+Birth+Defects&rft.au=Lawson%2C+Christina+C%3BSchnorr%2C+Teresa+M%3BWhelan%2C+Elizabeth+A%3BDeddens%2C+James+A%3BDankovic%2C+David+A%3BPiacitelli%2C+Laurie+A%3BSweeney%2C+Marie+H&rft.aulast=Lawson&rft.aufirst=Christina&rft.date=2004-10-01&rft.volume=112&rft.issue=14&rft.spage=1403&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; REPRODUCTION, HUMAN; BIRTH DEFECTS, HUMAN; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Classification of the Australian continental shelf based on predicted sediment threshold exceedance from tidal currents and swell waves AN - 17305344; 6143397 AB - Estimates of significant wave height and period, together with tidal current speed over a semi-lunar cycle, were used to predict the area on the Australian continental shelf over which unconsolidated sediment was mobilised (threshold exceedance). These sediment-entraining processes were examined independently to quantify their relative importance on the continental shelf. Using observed grain size data, mobilisation from swell waves occurred on ~31% and tidal currents on ~41% of the continental shelf. Swell wave energy is sufficient to mobilise fine sand (0.1 mm diameter) to a water depth of 142 m on the Otway Shelf near the western entrance to Bass Strait. Tidal currents in King Sound (northwest shelf) are capable of mobilising large areas of medium sand (0.35 mm diameter) 100% of the time. Superimposing the distribution of threshold exceedance by wave and tidal currents indicates that there are areas on the shelf where either wave-induced or tidal currents dominate, some areas where waves and tides are of relatively equal importance and still other areas where neither is significant. We define six shelf regions of relative wave and tidal energy: zero (no-mobility); waves-only, wave-dominated, mixed, tide-dominated and tides-only. Our results provide a predictive, process-based understanding of the shelf sedimentary system that has applications to marine engineering projects and to regional studies of pollution dispersal and accumulation where significant shelf sediment mobilisation is a factor. JF - Marine Geology AU - Porter-Smith, R AU - Harris, P T AU - Andersen, O B AU - Coleman, R AU - Greenslade, D AU - Jenkins, C J AD - Geoscience Australia, GPO Box 378, ACT, 2601, Canberra, Australia Y1 - 2004/09/30/ PY - 2004 DA - 2004 Sep 30 SP - 1 EP - 20 VL - 211 IS - 1-2 SN - 0025-3227, 0025-3227 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts KW - Q5 01503:Characteristics, behavior and fate KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17305344?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Geology&rft.atitle=Classification+of+the+Australian+continental+shelf+based+on+predicted+sediment+threshold+exceedance+from+tidal+currents+and+swell+waves&rft.au=Porter-Smith%2C+R%3BHarris%2C+P+T%3BAndersen%2C+O+B%3BColeman%2C+R%3BGreenslade%2C+D%3BJenkins%2C+C+J&rft.aulast=Porter-Smith&rft.aufirst=R&rft.date=2004-09-30&rft.volume=211&rft.issue=1-2&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Marine+Geology&rft.issn=00253227&rft_id=info:doi/10.1016%2Fj.margeo.2004.05.031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-03-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.margeo.2004.05.031 ER - TY - JOUR T1 - CD44 modulates Smad1 activation in the BMP-7 signaling pathway. AN - 66917507; 15452148 AB - Bone morphogenetic protein 7 (BMP-7) regulates cellular metabolism in embryonic and adult tissues. Signal transduction occurs through the activation of intracellular Smad proteins. In this paper, using a yeast two-hybrid screen, Smad1 was found to interact with the cytoplasmic domain of CD44, a receptor for the extracellular matrix macromolecule hyaluronan. Coimmunoprecipitation experiments confirmed the interaction of Smad1 with full-length CD44-interactions that did not occur when CD44 receptors truncated within the cytoplasmic domain were tested. Chondrocytes overexpressing a truncated CD44 on a background of endogenous full-length CD44 no longer exhibited Smad1 nuclear translocation upon BMP-7 stimulation. Further, pretreatment of chondrocytes with Streptomyces hyaluronidase to disrupt extracellular hyaluronan-cell interactions inhibited BMP-7-mediated Smad1 phosphorylation, nuclear translocation of Smad1 or Smad4, and SBE4-luciferase reporter activation. These results support a functional link between the BMP signaling cascade and CD44. Thus, changes in hyaluronan-cell interactions may serve as a means to modulate cellular responsiveness to BMP. JF - The Journal of cell biology AU - Peterson, Richard S AU - Andhare, Roma A AU - Rousche, Kathleen T AU - Knudson, Warren AU - Wang, Weihua AU - Grossfield, Jami B AU - Thomas, Raymond O AU - Hollingsworth, Robert E AU - Knudson, Cheryl B AD - Dept. of Biochemistry, Rush Medical College, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA. Y1 - 2004/09/27/ PY - 2004 DA - 2004 Sep 27 SP - 1081 EP - 1091 VL - 166 IS - 7 SN - 0021-9525, 0021-9525 KW - Antigens, CD44 KW - 0 KW - BMP7 protein, human KW - Bone Morphogenetic Protein 7 KW - Bone Morphogenetic Proteins KW - DNA-Binding Proteins KW - SMAD1 protein, human KW - SMAD4 protein, human KW - Smad Proteins KW - Smad1 Protein KW - Smad4 Protein KW - Trans-Activators KW - Transcription Factors KW - Transforming Growth Factor beta KW - Hyaluronic Acid KW - 9004-61-9 KW - Hyaluronoglucosaminidase KW - EC 3.2.1.35 KW - Index Medicus KW - Animals KW - COS Cells KW - Transcription Factors -- metabolism KW - Active Transport, Cell Nucleus -- drug effects KW - Humans KW - Two-Hybrid System Techniques KW - Hyaluronic Acid -- metabolism KW - Transcription Factors -- genetics KW - Hyaluronoglucosaminidase -- pharmacology KW - Phosphorylation -- drug effects KW - Mutagenesis, Site-Directed KW - Cattle KW - Genes, Reporter -- genetics KW - Transfection KW - Active Transport, Cell Nucleus -- genetics KW - Trans-Activators -- metabolism KW - Extracellular Matrix -- metabolism KW - Antigens, CD44 -- genetics KW - DNA-Binding Proteins -- genetics KW - Bone Morphogenetic Proteins -- genetics KW - Cartilage -- growth & development KW - Antigens, CD44 -- metabolism KW - Trans-Activators -- genetics KW - Cartilage -- metabolism KW - Chondrocytes -- drug effects KW - Cartilage -- cytology KW - Signal Transduction -- drug effects KW - Bone Morphogenetic Proteins -- metabolism KW - Signal Transduction -- genetics KW - Transforming Growth Factor beta -- genetics KW - Transforming Growth Factor beta -- metabolism KW - Chondrocytes -- metabolism KW - DNA-Binding Proteins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66917507?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+cell+biology&rft.atitle=CD44+modulates+Smad1+activation+in+the+BMP-7+signaling+pathway.&rft.au=Peterson%2C+Richard+S%3BAndhare%2C+Roma+A%3BRousche%2C+Kathleen+T%3BKnudson%2C+Warren%3BWang%2C+Weihua%3BGrossfield%2C+Jami+B%3BThomas%2C+Raymond+O%3BHollingsworth%2C+Robert+E%3BKnudson%2C+Cheryl+B&rft.aulast=Peterson&rft.aufirst=Richard&rft.date=2004-09-27&rft.volume=166&rft.issue=7&rft.spage=1081&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+cell+biology&rft.issn=00219525&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-12-02 N1 - Date created - 2004-09-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Nat Rev Cancer. 2004 Jul;4(7):528-39 [15229478] Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12160-4 [1465456] Connect Tissue Res. 1992;28(1-2):143-59 [1628488] Science. 2000 Jan 7;287(5450):92-7 [10615055] Arthritis Rheum. 2000 Jan;43(1):206-14 [10643717] J Histochem Cytochem. 2000 Feb;48(2):239-50 [10639490] Osteoarthritis Cartilage. 2000 Mar;8(2):127-36 [10772243] Arthritis Rheum. 2000 May;43(5):1165-74 [10817571] Genomics. 2000 Oct 1;69(1):63-71 [11013076] J Biol Chem. 2001 May 25;276(21):17871-7 [11278410] J Cell Biol. 2001 May 28;153(5):893-904 [11381077] Biochem J. 2001 Aug 1;357(Pt 3):843-50 [11463356] J Biol Chem. 2001 Oct 19;276(42):39404-10 [11509558] Crit Rev Eukaryot Gene Expr. 2001;11(1-3):23-45 [11693963] Arthritis Rheum. 2001 Nov;44(11):2599-610 [11710716] J Cell Biol. 2001 Nov 26;155(5):755-62 [11714729] Mol Cell. 2001 Dec;8(6):1303-12 [11779505] J Cell Sci. 2001 Dec;114(Pt 24):4359-69 [11792802] Matrix Biol. 2002 Jan;21(1):53-62 [11827792] Cell Mol Life Sci. 2002 Jan;59(1):36-44 [11846031] J Biol Chem. 2002 Mar 22;277(12):10531-8 [11792695] J Biol Chem. 2002 Nov 22;277(47):44754-9 [12223485] Biochim Biophys Acta. 2003 Jan 3;1625(1):30-5 [12527423] Oncogene. 2003 Mar 13;22(10):1511-6 [12629514] J Biol Chem. 2003 May 16;278(20):17688-700 [12637574] J Cell Biol. 2003 Jun 9;161(5):839-43 [12796473] Biochem Biophys Res Commun. 2003 Aug 1;307(3):632-9 [12893270] Birth Defects Res C Embryo Today. 2003 May;69(2):174-96 [12955860] J Cell Sci. 2004 Jan 26;117(Pt 3):373-80 [14702383] J Cell Sci. 1992 Oct;103 ( Pt 2):293-8 [1282514] FASEB J. 1993 Oct;7(13):1233-41 [7691670] J Biol Chem. 1995 Nov 17;270(46):27734-41 [7499241] Biotechniques. 1996 Aug;21(2):255-9 [8862810] Arthritis Rheum. 1996 Nov;39(11):1896-904 [8912513] Nat Biotechnol. 1998 Mar;16(3):247-52 [9528003] J Biol Chem. 1998 Aug 14;273(33):21145-52 [9694870] J Biol Chem. 1998 Sep 4;273(36):22865-8 [9722503] J Biol Chem. 1998 Oct 2;273(40):25628-36 [9748228] Nature. 1999 Apr 8;398(6727):518-22 [10206645] Exp Cell Res. 1999 Nov 1;252(2):292-302 [10527620] Dev Biol. 1987 Nov;124(1):82-90 [2444482] N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - Co-evolution of controversial theories AN - 39843942; 3878856 AU - Steen, T Y1 - 2004/09/21/ PY - 2004 DA - 2004 Sep 21 KW - CPI, Conference Papers Index KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39843942?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Co-evolution+of+controversial+theories&rft.au=Steen%2C+T&rft.aulast=Steen&rft.aufirst=T&rft.date=2004-09-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Pennsylvania State University, College of Earth and Mineral Sciences, 116 Deike Building, University Park, PA 16802, USA; URL: www.outreach.psu.edu N1 - Last updated - 2010-05-03 ER - TY - GEN T1 - Nomination of the Honorable Porter J. Goss to Be Director of Central Intelligence AN - 1679147032; CO02125 AB - Transcribes Senate Select Committee on Intelligence hearing about nomination of Porter Goss for director of central intelligence. AU - United States. Congress. Senate. Select Committee on Intelligence AD - United States. Congress. Senate. Select Committee on Intelligence PY - 2004 SP - 210 KW - Biography KW - Confirmation hearings KW - Government budgeting KW - Human intelligence KW - Intelligence cooperation KW - Iraq War (2003-) KW - Military intelligence KW - New York Times KW - News media KW - September 11 Attacks (2001) KW - Washington Post KW - Washington Times KW - Weapons of mass destruction KW - Mikulski, Barbara A. KW - DeWine, Michael KW - Levin, Carl KW - Thomas, Cynthia A. KW - Hussein, Saddam KW - Kerry, John F. KW - Bush, George W. KW - Warner, John William KW - Durbin, Richard J. KW - Glynn, Marilyn L. KW - Bayh, Evan KW - Hatch, Orrin G. KW - Goss, Porter J. KW - Hagel, Charles T. KW - Feinstein, Dianne KW - Nelson, William E. KW - Rockefeller, John D. IV ("Jay") KW - Graham, Robert KW - Chambliss, Saxby KW - Rizzo, John A. KW - Wyden, Ron KW - Snowe, Olympia J. KW - Roberts, Charles Patrick KW - Mikulski, Barbara A. KW - DeWine, Michael KW - Levin, Carl KW - Thomas, Cynthia A. KW - Hussein, Saddam KW - Kerry, John F. KW - Bush, George W. KW - Warner, John William KW - Durbin, Richard J. KW - Glynn, Marilyn L. KW - Bayh, Evan KW - Hatch, Orrin G. KW - Goss, Porter J. KW - Hagel, Charles T. KW - Feinstein, Dianne KW - Nelson, William E. KW - Rockefeller, John D. IV ("Jay") KW - Graham, Robert KW - Chambliss, Saxby KW - Rizzo, John A. KW - Wyden, Ron KW - Snowe, Olympia J. KW - Roberts, Charles Patrick UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679147032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_co&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Nomination+of+the+Honorable+Porter+J.+Goss+to+Be+Director+of+Central+Intelligence&rft.au=United+States.+Congress.+Senate.+Select+Committee+on+Intelligence&rft.aulast=United+States.+Congress.+Senate.+Select+Committee+on+Intelligence&rft.aufirst=&rft.date=2004-09-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - Al-Qaeda; Democratic Party; National Commission on Terrorist Attacks upon the United States; TriDimension Strategies; United States. Central Intelligence Agency; United States. Congress. House. Permanent Select Committee on Intelligence; United States. Department of Defense. Secretary; United States. Director of Central Intelligence; United States. Federal Bureau of Investigation. Director N1 - Analyte descriptor - NSA document type: Hearing N1 - People - Bayh, Evan; Bush, George W.; Chambliss, Saxby; DeWine, Michael; Durbin, Richard J.; Feinstein, Dianne; Glynn, Marilyn L.; Goss, Porter J.; Graham, Robert; Hagel, Charles T.; Hatch, Orrin G.; Hussein, Saddam; Kerry, John F.; Levin, Carl; Mikulski, Barbara A.; Nelson, William E.; Rizzo, John A.; Roberts, Charles Patrick; Rockefeller, John D. IV ("Jay"); Snowe, Olympia J.; Thomas, Cynthia A.; Warner, John William; Wyden, Ron N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - A bidirectional gene trap construct suitable for T-DNA and Ds-mediated insertional mutagenesis in rice (Oryza sativa L.). AN - 734178568; 17168884 AB - A construct suitable for genome-wide transfer-DNA (T-DNA) and subsequent transposon-based (Ds) gene trapping has been developed for use in rice (Oryza sativa). This T-DNA/Ds construct contains: Ds terminal sequences immediately inside T-DNA borders for subsequent Ds mobilization; promoterless green fluorescent protein (sgfpS65T) and beta-glucuronidase (uidA) reporter genes, each fused to an intron (from Arabidopsis GPA1 gene) to enable bidirectional gene trapping by T-DNA or Ds; an ampicillin resistance gene (bla) and a bacterial origin of replication (ori) to serve as the plasmid rescue system; an intron-containing hygromycin phosphotransferase gene (hph) as a selectable marker or Ds tracer; and an intron-containing barnase gene in the binary vector backbone (VB) to select against transformants carrying unwanted VB sequences. More than a threefold increase over previously reported reporter gene-based gene trapping efficiencies was observed in primary T-DNA/Ds transformant rice lines, returning an overall reporter gene expression frequency of 23%. Of the plant organs tested, 3.3-7.4% expressed either reporter at varying degrees of organ or tissue specificity. Approximately 70% of the right border (RB) flanking sequence tags (FSTs) retained 1-6 bp of the RB repeat and 30% of the left border (LB) FSTs retained 5-23 bp of the LB repeat. The remaining FSTs carried deletions of 2-84 bp inside the RB or 1-97 bp inside the LB. Transposition of Ds from the original T-DNA was evident in T-DNA/Ds callus lines super-transformed with a transposase gene (Ac) construct, as indicated by gene trap reporter activity and rescue of new FSTs in the resulting double transformant lines. JF - Plant biotechnology journal AU - Eamens, Andrew L AU - Blanchard, Chris L AU - Dennis, Elizabeth S AU - Upadhyaya, Narayana M AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia. Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 367 EP - 380 VL - 2 IS - 5 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734178568?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+biotechnology+journal&rft.atitle=A+bidirectional+gene+trap+construct+suitable+for+T-DNA+and+Ds-mediated+insertional+mutagenesis+in+rice+%28Oryza+sativa+L.%29.&rft.au=Eamens%2C+Andrew+L%3BBlanchard%2C+Chris+L%3BDennis%2C+Elizabeth+S%3BUpadhyaya%2C+Narayana+M&rft.aulast=Eamens&rft.aufirst=Andrew&rft.date=2004-09-01&rft.volume=2&rft.issue=5&rft.spage=367&rft.isbn=&rft.btitle=&rft.title=Plant+biotechnology+journal&rft.issn=1467-7652&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-02 N1 - Date created - 2006-12-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The Law: Recess Appointments to Article III Courts AN - 60709040; 200502754 AB - Under the Constitution, the president & the Senate share the power to appoint officers of the US, including federal judges. The Constitution also empowers the president to make temporary appointments without the Senate's approval during Senate recesses. Presidents have made over 300 recess appointments to Article III courts, but the practice has become rare in the last 40 years. Although courts have found tension between Article II & Article III inherent in judicial recess appointments, the practice has been held to be constitutional. Intrasession recess appointments, particularly during recesses of less than 30 days, have sometimes proven controversial. 1 Table, 38 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Hogue, Henry B AD - Congressional Research Service, Library Congress Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 656 EP - 673 VL - 34 IS - 3 SN - 0360-4918, 0360-4918 KW - Appointment KW - Presidents KW - United States of America KW - Legislative Bodies KW - Constitutions KW - Judges KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60709040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=The+Law%3A+Recess+Appointments+to+Article+III+Courts&rft.au=Hogue%2C+Henry+B&rft.aulast=Hogue&rft.aufirst=Henry&rft.date=2004-09-01&rft.volume=34&rft.issue=3&rft.spage=656&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 38 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States of America; Presidents; Legislative Bodies; Judges; Appointment; Constitutions ER - TY - JOUR T1 - IDA Grants and HIPC Debt Cancellation: Their Effectiveness and Impact on IDA Resources AN - 59692635; 200602771 AB - IDA is in trouble. The World Bank's long-term plans presume that IDA will need all the loan repayments currently scheduled just to keep its program from shrinking in future decades. Yet the IDA grant & HIPC debt reduction programs are cutting the flow of repayments, foreshadowing major future cuts in IDA aid. Unless the donor countries agree on a plan to offset those costs, poor countries will suffer. Meanwhile, the efficiency & effectiveness of the grant & debt cancellation programs have been seriously questioned. These programs are evaluated & changes in the Bank's future plans for IDA are proposed. 3 Tables, 4 Figures, 82 References. [Copyright 2004 Elsevier Ltd.] JF - World Development AU - Sanford, Jonathan E AD - Congressional Research Service, Library Congress, Washington, DC Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 1579 EP - 1607 VL - 32 IS - 9 SN - 0305-750X, 0305-750X KW - Foreign Aid KW - Public Debt KW - Loans KW - Economic Development KW - International Economic Organizations KW - article KW - 9141: political economy; political economy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59692635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=World+Development&rft.atitle=IDA+Grants+and+HIPC+Debt+Cancellation%3A+Their+Effectiveness+and+Impact+on+IDA+Resources&rft.au=Sanford%2C+Jonathan+E&rft.aulast=Sanford&rft.aufirst=Jonathan&rft.date=2004-09-01&rft.volume=32&rft.issue=9&rft.spage=1579&rft.isbn=&rft.btitle=&rft.title=World+Development&rft.issn=0305750X&rft_id=info:doi/10.1016%2Fj.worlddev.2004.04.001 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 82 N1 - Last updated - 2016-09-28 N1 - CODEN - WODEDW N1 - SubjectsTermNotLitGenreText - Economic Development; International Economic Organizations; Public Debt; Loans; Foreign Aid DO - http://dx.doi.org/10.1016/j.worlddev.2004.04.001 ER - TY - JOUR T1 - Follow-Up Study of Adolescents Exposed to Di(2-Ethylhexyl) Phthalate (DEHP) as Neonates on Extracorporeal Membrane Oxygenation (ECMO) Support AN - 21194225; 11492289 AB - Di(2-ethylhexyl) phthalate (DEHP) is used to make polyvinyl chloride (PVC) plastic tubing soft and flexible. Animal data show that adverse effects of DEHP exposure may include reduced fertility, reduced sperm production in males, and ovarian dysfunction in females. Known treatments that involve high DEHP exposures are blood exchange transfusions, extracorporeal membrane oxygenation (ECMO), and cardiovascular surgery. Although potential exposure to DEHP in ECMO patients is significant, the exposure has not been associated with short-term toxicity. To evaluate long-term toxicity, we undertook a study of neonatal ECMO survivors to assess their onset of puberty and sexual maturity. We evaluated 13 male and 6 female subjects at 14-16 years of age who had undergone ECMO as neonates. All subjects had a complete physical examination including measurements for height, weight, head circumference, and pubertal assessment by Tanner staging. The testicular volume and the phallic length were measured in male participants. Laboratory tests included thyroid, liver, and renal function as well as measurements of luteinizing hormone, follicle-stimulating hormone, testosterone for males, and estradiol for females. Except for one patient with Marfan syndrome, the rest had normal growth percentile for age and sex. All had normal values for thyroid, liver, and renal functions. Sexual hormones were appropriate for the stage of pubertal maturity. Our results indicate that adolescents exposed to significant quantities of DEHP as neonates showed no significant adverse effects on their physical growth and pubertal maturity. Thyroid, liver, renal, and male and female gonadal functions tested were within normal range for age and sex distribution. Key Words: DEHP, ECMO, toxicity. JF - Environmental Health Perspectives AU - Rais-Bahrami, Khodayar AU - Nunez, Susan AU - Revenis, Mary E AU - Luban, Naomi L C AU - Short, Billie L Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1339 EP - 1340 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts; Environment Abstracts; Environmental Engineering Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21194225?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Follow-Up+Study+of+Adolescents+Exposed+to+Di%282-Ethylhexyl%29+Phthalate+%28DEHP%29+as+Neonates+on+Extracorporeal+Membrane+Oxygenation+%28ECMO%29+Support&rft.au=Rais-Bahrami%2C+Khodayar%3BNunez%2C+Susan%3BRevenis%2C+Mary+E%3BLuban%2C+Naomi+L+C%3BShort%2C+Billie+L&rft.aulast=Rais-Bahrami&rft.aufirst=Khodayar&rft.date=2004-09-01&rft.volume=111&rft.issue=8&rft.spage=1131&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Developmental Dental Aberrations After the Dioxin Accident in Seveso AN - 21188687; 11492280 AB - Children's developing teeth may be sensitive to environmental dioxins, and in animal studies developing teeth are one of the most sensitive targets of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Twenty-five years after the dioxin accident in Seveso, Italy, 48 subjects from the contaminated areas (zones A and B) and in patches lightly contaminated (zone R) were recruited for the examination of dental and oral aberrations. Subjects were randomly invited from those exposed in their childhood and for whom frozen serum samples were available. The subjects were frequency matched with 65 subjects from the surrounding non-ABR zone for age, sex, and education. Concentrations of TCDD in previously analyzed plasma samples (zone ABR subjects only) ranged from 23 to 26,000 ng/kg in serum lipid. Ninety-three percent (25 of 27) of the subjects who had developmental enamel defects had been 5 years of age at the time of the accident. The prevalence of defects in this age group was 42% (15 of 36) in zone ABR subjects and 26% (10 of 39) in zone non-ABR subjects, correlating with serum TCDD levels (p = 0.016). Hypodontia was seen in 12.5% (6 of 48) and 4.6% (3 of 65) of the zone ABR and non-ABR subjects, respectively, also correlating with serum TCDD level (p = 0.05). In conclusion, developmental dental aberrations were associated with childhood exposure to TCDD. In contrast, dental caries and periodontal disease, both infectious in nature, and oral pigmentation and salivary flow rate were not related to the exposure. The results support our hypothesis that dioxins can interfere with human organogenesis. JF - Environmental Health Perspectives AU - Alaluusua, Satu AU - Calderara, Pier AU - Gerthoux, Pier Mario AU - Lukinmaa, Pirjo-Liisa Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1313 EP - 1318 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21188687?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developmental+Dental+Aberrations+After+the+Dioxin+Accident+in+Seveso&rft.au=Alaluusua%2C+Satu%3BCalderara%2C+Pier%3BGerthoux%2C+Pier+Mario%3BLukinmaa%2C+Pirjo-Liisa&rft.aulast=Alaluusua&rft.aufirst=Satu&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1313&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Postweaning Exposure to Aflatoxin Results in Impaired Child Growth: A Longitudinal Study in Benin, West Africa AN - 21186869; 11492279 AB - Aflatoxins are dietary contaminants that are hepatocarcinogenic and immunotoxic and cause growth retardation in animals, but there is little evidence concerning the latter two parameters in exposed human populations. Aflatoxin exposure of West African children is known to be high, so we conducted a longitudinal study over an 8-month period in Benin to assess the effects of exposure on growth. Two hundred children 16-37 months of age were recruited from four villages, two with high and two with low aflatoxin exposure (50 children per village). Serum aflatoxin-albumin (AF-alb) adducts, anthropometric parameters, information on food consumption, and various demographic data were measured at recruitment (February) and at two subsequent time points (June and October). Plasma levels of vitamin A and zinc were also measured. AF-alb adducts increased markedly between February and October in three of the four villages, with the largest increases in the villages with higher exposures. Children who were fully weaned at recruitment had higher AF-alb than did those still partially breast-fed (p 0.0001); the major weaning food was a maize-based porridge. There was no association between AF-alb and micronutrient levels, suggesting that aflatoxin exposure was not accompanied by a general nutritional deficiency. There was, however, a strong negative correlation (p 0.0001) between AF-alb and height increase over the 8-month follow-up after adjustment for age, sex, height at recruitment, socioeconomic status, village, and weaning status; the highest quartile of AF-alb was associated with a mean 1.7 cm reduction in growth over 8 months compared with the lowest quartile. This study emphasizes the association between aflatoxin and stunting, although the underlying mechanisms remain unclear. Aflatoxin exposure during the weaning period may be critical in terms of adverse health effects in West African children, and intervention measures to reduce exposure merit investigation. JF - Environmental Health Perspectives AU - Gong, Yunyun AU - Hounsa, Assomption AU - Egal, Sharif AU - Turner, Paul C Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1334 EP - 1338 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24320:Food Additives & Contaminants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21186869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Postweaning+Exposure+to+Aflatoxin+Results+in+Impaired+Child+Growth%3A+A+Longitudinal+Study+in+Benin%2C+West+Africa&rft.au=Gong%2C+Yunyun%3BHounsa%2C+Assomption%3BEgal%2C+Sharif%3BTurner%2C+Paul+C&rft.aulast=Gong&rft.aufirst=Yunyun&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1334&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Subcutaneous Injection of Mercury: "Warding Off Evil" AN - 21185793; 11492286 AB - Deliberate injection of mercury, especially subcutaneous injection, is rare but is seen in psychiatric patients, individuals who attempt suicide, those who are accidentally injected, and boxers who wish to build muscle bulk. Metallic mercury plays a major role in ethnic folk medicine. Neurologic and renal complications can result from high systemic levels of mercury, and subcutaneous injection usually results in sterile abscesses. Urgent surgical evacuation and close monitoring for neurologic and renal functions as well as chelation (if toxicity is indicated) are key aspects of treatment. Education of the adverse effects and dangers of mercury is important, especially in pregnant women and children. As increased immigration changes demographic patterns, proper disposal of mercury and preventing its sale and use should become urgent societal priorities. Psychiatric consultation should be obtained whenever appropriate. JF - Environmental Health Perspectives AU - Prasad, Venkat L Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1326 EP - 1328 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21185793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Subcutaneous+Injection+of+Mercury%3A+%22Warding+Off+Evil%22&rft.au=Prasad%2C+Venkat+L&rft.aulast=Prasad&rft.aufirst=Venkat&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1326&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Water Arsenic Exposure and Children's Intellectual Function in Araihazar, Bangladesh AN - 21185765; 11492283 AB - Exposure to arsenic has long been known to have neurologic consequences in adults, but to date there are no well-controlled studies in children. We report results of a cross-sectional investigation of intellectual function in 201 children 10 years of age whose parents participate in our ongoing prospective cohort study examining health effects of As exposure in 12,000 residents of Araihazar, Bangladesh. Water As and manganese concentrations of tube wells at each child's home were obtained by surveying all wells in the study region. Children and mothers came to our field clinic, where children received a medical examination in which weight, height, and head circumference were measured. Children's intellectual function on tests drawn from the Wechsler Intelligence Scale for Children, version III, was assessed by summing weighted items across domains to create Verbal, Performance, and Full-Scale raw scores. Children provided urine specimens for measuring urinary As and creatinine and were asked to provide blood samples for measuring blood lead and hemoglobin concentrations. Exposure to As from drinking water was associated with reduced intellectual function after adjustment for sociodemographic covariates and water Mn. Water As was associated with reduced intellectual function, in a dose-response manner, such that children with water As levels 50 microg/L achieved significantly lower Performance and Full-Scale scores than did children with water As levels 5.5 microg/L. The association was generally stronger for well-water As than for urinary As. JF - Environmental Health Perspectives AU - Wasserman, Gail A AU - Liu, Xinhua AU - Parvez, Faruque AU - Ahsan, Habibul Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1329 EP - 1333 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21185765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Water+Arsenic+Exposure+and+Children%27s+Intellectual+Function+in+Araihazar%2C+Bangladesh&rft.au=Wasserman%2C+Gail+A%3BLiu%2C+Xinhua%3BParvez%2C+Faruque%3BAhsan%2C+Habibul&rft.aulast=Wasserman&rft.aufirst=Gail&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1329&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - A Bayesian Hierarchical Approach for Relating PM sigma ub 2.5Exposure to Cardiovascular Mortality in North Carolina AN - 21165717; 11492285 AB - Considerable attention has been given to the relationship between levels of fine particulate matter (particulate matter or = 2.5 microm in aerodynamic diameter; PM(2.5) in the atmosphere and health effects in human populations. Since the U.S. Environmental Protection Agency began widespread monitoring of PM(2.5) levels in 1999, the epidemiologic community has performed numerous observational studies modeling mortality and morbidity responses to PM(2.5) levels using Poisson generalized additive models (GAMs). Although these models are useful for relating ambient PM(2.5) levels to mortality, they cannot directly measure the strength of the effect of exposure to PM(2.5) on mortality. In order to assess this effect, we propose a three-stage Bayesian hierarchical model as an alternative to the classical Poisson GAM. Fitting our model to data collected in seven North Carolina counties from 1999 through 2001, we found that an increase in PM(2.5) exposure is linked to increased risk of cardiovascular mortality in the same day and next 2 days. Specifically, a 10- microg/m3 increase in average PM(2.5) exposure is associated with a 2.5% increase in the relative risk of current-day cardiovascular mortality, a 4.0% increase in the relative risk of cardiovascular mortality the next day, and an 11.4% increase in the relative risk of cardiovascular mortality 2 days later. Because of the small sample size of our study, only the third effect was found to have 95% posterior probability of being 0. In addition, we compared the results obtained from our model to those obtained by applying frequentist (or classical, repeated sampling-based) and Bayesian versions of the classical Poisson GAM to our study population. JF - Environmental Health Perspectives AU - Holloman, Christopher H AU - Bortnick, Steven M AU - Morara, Michele AU - Strauss, Warren J AU - Calder, Catherine A Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1282 EP - 1288 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Risk Abstracts; Environment Abstracts; Environmental Engineering Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21165717?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=A+Bayesian+Hierarchical+Approach+for+Relating+PM+sigma+ub+2.5Exposure+to+Cardiovascular+Mortality+in+North+Carolina&rft.au=Holloman%2C+Christopher+H%3BBortnick%2C+Steven+M%3BMorara%2C+Michele%3BStrauss%2C+Warren+J%3BCalder%2C+Catherine+A&rft.aulast=Holloman&rft.aufirst=Christopher&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1282&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Dioxin Revisited: Developments Since the 1997 IARC Classification of Dioxin as a Human Carcinogen AN - 21161451; 11492282 AB - In 1997 the International Agency for Research on Cancer (IARC) classified 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; the most potent dioxin congener) as a group 1 carcinogen based on limited evidence in humans, sufficient evidence in experimental animals, and extensive mechanistic information indicating that TCDD acts through a mechanism involving the aryl hydrocarbon receptor (AhR), which is present in both humans and animals. The judgment of limited evidence in humans was based primarily on an elevation of all cancers combined in four industrial cohorts. The group 1 classification has been somewhat controversial and has been challenged in the literature in recent years. In this article we review the epidemiologic and mechanistic evidence that has emerged since 1997. New epidemiologic evidence consists primarily of positive exposure-response analyses in several of the industrial cohorts, as well as evidence of excesses of several specific cancers in the Seveso accident cohort. There are also new data regarding how the AhR functions in mediating the carcinogenic response to TCDD. The new evidence generally supports the 1997 IARC classification. JF - Environmental Health Perspectives AU - Steenland, Kyle AU - Bertazzi, Pier AU - Baccarelli, Andrea AU - Kogevinas, Manolis Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1265 EP - 1268 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21161451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Dioxin+Revisited%3A+Developments+Since+the+1997+IARC+Classification+of+Dioxin+as+a+Human+Carcinogen&rft.au=Steenland%2C+Kyle%3BBertazzi%2C+Pier%3BBaccarelli%2C+Andrea%3BKogevinas%2C+Manolis&rft.aulast=Metcalfe&rft.aufirst=D&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5810 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Serum Dioxin Concentrations and Age at Menarche AN - 21140186; 11492288 AB - 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a widespread environmental contaminant, is associated with delays in pubertal development in animal studies. On 10 July 1976, as a result of a chemical explosion, residents of Seveso, Italy, experienced the highest levels of TCDD exposure experienced by a human population. Twenty years later, we initiated the Seveso Women's Health Study (SWHS), a retrospective cohort study of female residents of the most contaminated areas, to determine whether the women were at higher risk for reproductive disease. We examined the association of TCDD serum levels, based on measurements in serum collected soon after the explosion, with reported age at menarche among the 282 SWHS women who were premenarcheal at the time of the explosion. We found no change in risk of onset of menarche with a 10-fold increase in TCDD (e.g., 10-100 ppt; hazard ratio = 0.95; 95% confidence interval, 0.83-1.09; p-value for trend = 0.46). When TCDD levels were categorized, there was also no evidence of a dose-response trend (p = 0.65). In summary, we found that individual serum TCDD measurements are not significantly related to age at menarche among women in the SWHS cohort. The women in this study experienced substantial TCDD exposure during the postnatal but prepubertal developmental period. Given that animal evidence suggests in utero exposure has the most significant effect on onset of puberty, continued follow-up of the offspring of the SWHS cohort is important. JF - Environmental Health Perspectives AU - Warner, Marcella AU - Samuels, Steven AU - Mocarelli, Paolo AU - Gerthoux, Pier Mario Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1289 EP - 1292 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 USA VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - A 01450:Environmental Pollution & Waste Treatment KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21140186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Serum+Dioxin+Concentrations+and+Age+at+Menarche&rft.au=Warner%2C+Marcella%3BSamuels%2C+Steven%3BMocarelli%2C+Paolo%3BGerthoux%2C+Pier+Mario&rft.aulast=Warner&rft.aufirst=Marcella&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1289&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Habitat structure mediates the non-lethal effects of predation on enclosed populations of house mice AN - 18061152; 6011171 AB - Prey behavioural changes in response to predation risk can result in significant effects on prey body growth rates and reduced reproductive output, with resultant impacts on prey population dynamics. This paper examines the influence of habitat structure on these non-lethal impacts of predation using a model, field-based experimental system, with house mice as prey. Three treatments were employed in eight 50 x 50 m pens that contained mice, but allowed access to a suite of free-living vertebrate predators, which included feral foxes, feral cats and native raptors: a treatment where the natural grassland vegetation in the pens was maintained at a height < 10 cm; a treatment where small, felled cypress pine trees covered with wire netting were added to low grassland vegetation to create refuge areas covering 10-15% of the area in a pen; and a treatment where predators were excluded from a 25 x 25 m section of some pens with an underlying grassland structure. A 5 x 5 grid of felled trees was added to grassland and predator-exclusion pens to allow assessment of mouse behaviour. Mice in grassland pens avoided open areas, had lower body growth rates, and began breeding later in spring than mice in both predator-exclusion areas, where they foraged more readily in the open, and in refuge pens, where mice avoided open areas but had safe access to supplementary food located within the refuge. These results occurred despite mouse population densities being much lower in grassland pens, and presumably competition for food being much less, compared with under the other treatments. The results indicate predators can have significant non-lethal impacts on prey, and these effects can be mediated by habitat structure. JF - Journal of Animal Ecology AU - Arthur, AD AU - Pech, R P AU - Dickman, C R AD - Pest Animal Control CRC, CSIRO Sustainable Ecosystems, GPO Box 284, Canberra, ACT, 2601, Australia, tony.arthur@csiro.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 867 EP - 877 PB - Blackwell Science Ltd VL - 73 IS - 5 SN - 0021-8790, 0021-8790 KW - Ecology Abstracts KW - Predator-prey interactions KW - Anti-predator behavior KW - Predation KW - Habitat preferences KW - Cover KW - Mus musculus KW - D 04672:Mammals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18061152?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Animal+Ecology&rft.atitle=Habitat+structure+mediates+the+non-lethal+effects+of+predation+on+enclosed+populations+of+house+mice&rft.au=Arthur%2C+AD%3BPech%2C+R+P%3BDickman%2C+C+R&rft.aulast=Arthur&rft.aufirst=AD&rft.date=2004-09-01&rft.volume=73&rft.issue=5&rft.spage=867&rft.isbn=&rft.btitle=&rft.title=Journal+of+Animal+Ecology&rft.issn=00218790&rft_id=info:doi/10.1111%2Fj.0021-8790.2004.00864.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Mus musculus; Predation; Habitat preferences; Cover; Predator-prey interactions; Anti-predator behavior DO - http://dx.doi.org/10.1111/j.0021-8790.2004.00864.x ER - TY - JOUR T1 - Biases associated with the use of underwater visual census techniques to quantify the density and size-structure of fish populations AN - 18057035; 5977778 AB - Estimates of reef fish densities made by divers visually censusing 5 m wide strip transects were compared with capture-resight estimates calculated independently using data on the resighting frequencies of fish marked with colour-coded tags. The difference in density estimates between methods varied between species but with patterns consistent at the three eastern Tasmanian sites studied. Densities of the two most abundant species, the wrasses Notolabrus tetricus and Notolabrus fucicola, showed good agreement between methods. By contrast, populations of the two monacanthids Meuschenia australis and Meuschenia freycineti were underestimated by an order of magnitude in strip transects relative to capture-resight, while populations of the open-water latrid Latridopsis forsteri were overestimated. For all common fish species observed in strip transects, variation in density estimates between divers was extremely low compared to variation between sites and between months. Variation in density estimates between different days within a week and between 50 m blocks located 50 m apart was also negligible; however, residual error associated with variation by a single diver within a block and day was high. Biases associated with changing detectability of fishes in open versus densely vegetated habitats were assessed by algal removal experiments, and were found to be negligible or non-significantly low for five of the six species examined. The exceptional species; N. tetricus; exhibited a 70% rise in fish sighted by diver following algal clearance despite trapping data indicating no increase in fish numbers. Diver estimates of fish length were on average 7% greater than measured lengths. Divers possessed a clear tendency to make increasingly inaccurate size estimates as fish length deviated in either direction from 300 mm. Lengths of 175-mm animals were underestimated by 20% and 400-mm fishes were overestimated by 10%. These changes in diver bias with fish size were largely independent of fish species, site and diver. The precision of size estimates, as indicated by the standard deviation of bias, also varied with fish size, with values varying from 13% at 200 mm fish length to 8% at 400 mm length. The decline in precision at small body size largely reflected size intervals used by divers to bin data. Divers appear capable of making more precise size estimates than the 25-mm interval used at small fish sizes. JF - Journal of Experimental Marine Biology and Ecology AU - Edgar, G J AU - Barrett, N S AU - Morton, A J AD - Zoology Department, Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, GPO Box 252-05, Hobart Tasmania, 7001, Australia, g.edgar@utas.edu.au Y1 - 2004/09// PY - 2004 DA - September 2004 SP - 269 EP - 290 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 308 IS - 2 SN - 0022-0981, 0022-0981 KW - Biases KW - Capture-resight estimates KW - Comparative studies KW - Silver trumpeter KW - Wrasse KW - Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Fish census KW - Notolabrus tetricus KW - Observer bias KW - Precision KW - Rocky reef KW - Strip transect KW - Viewing underwater KW - Reefs KW - Meuschenia freycineti KW - Population density KW - PSE, Australia, Tasmania, East Coast KW - Divers KW - Latridopsis forsteri KW - Body size KW - Habitat utilization KW - Meuschenia australis KW - Tagging KW - Notolabrus fucicola KW - Marine KW - Monocanthidae KW - Errors KW - Trapping KW - Methodology KW - Dominant species KW - Analytical techniques KW - Census KW - Population structure KW - Latridopsis KW - Size distribution KW - Reef fish KW - O 1070:Ecology/Community Studies KW - Q1 08382:Ecological techniques and apparatus KW - D 04001:Methodology - general UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18057035?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.atitle=Biases+associated+with+the+use+of+underwater+visual+census+techniques+to+quantify+the+density+and+size-structure+of+fish+populations&rft.au=Edgar%2C+G+J%3BBarrett%2C+N+S%3BMorton%2C+A+J&rft.aulast=Edgar&rft.aufirst=G&rft.date=2004-09-01&rft.volume=308&rft.issue=2&rft.spage=269&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.issn=00220981&rft_id=info:doi/10.1016%2Fj.jembe.2004.03.004 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Viewing underwater; Dominant species; Analytical techniques; Population density; Population structure; Census; Tagging; Errors; Size distribution; Divers; Reef fish; Methodology; Reefs; Body size; Habitat utilization; Trapping; Monocanthidae; Latridopsis forsteri; Meuschenia freycineti; Notolabrus tetricus; Meuschenia australis; Latridopsis; Notolabrus fucicola; PSE, Australia, Tasmania, East Coast; Marine DO - http://dx.doi.org/10.1016/j.jembe.2004.03.004 ER - TY - JOUR T1 - Benchmarking and regulation - Advantages and conflicts AN - 18057014; 6063856 AB - The two principal applications of benchmarking as it relates to water businesses are: 1. Those benchmarks undertaken by the water businesses (e.g. for internal and business improvements). 2. Those benchmarks undertaken on the water businesses. (e.g. for external regulatory, stakeholder, owner and consumer purposes.) My two contentions for this paper, based on experience, are: a) internal and external benchmark studies are incompatible; and b) benchmarking, for setting utility prices, should be an input process and not an output process. JF - Water (Australia) AU - Seipolt, A AD - Parsons Brinckerhoff International (Australia), Level 7, 457 St Kilda Rd, GPO Box 4714 TT, Melbourne, Victoria, Australia, seipolta@pbworld.com Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 42 EP - 43 VL - 31 IS - 6 SN - 0310-0367, 0310-0367 KW - Aqualine Abstracts KW - Pricing KW - Water Management KW - Decision Making KW - Utilities KW - AQ 00001:Water Resources and Supplies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18057014?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+%28Australia%29&rft.atitle=Benchmarking+and+regulation+-+Advantages+and+conflicts&rft.au=Seipolt%2C+A&rft.aulast=Seipolt&rft.aufirst=A&rft.date=2004-09-01&rft.volume=31&rft.issue=6&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Water+%28Australia%29&rft.issn=03100367&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Utilities; Pricing; Water Management; Decision Making ER - TY - JOUR T1 - Habitat structural complexity mediates the foraging success of multiple predator species AN - 18056604; 6018041 AB - We investigated the role of freshwater macrophytes as refuge by testing the hypothesis that predators capture fewer prey in more dense and structurally complex habitats. We also tested the hypothesis that habitat structure not only affects the prey-capture success of a single predator in isolation, but also the effectiveness of two predators combined, particularly if it mediates interactions between the predators. We conducted a fully crossed four-factorial laboratory experiment using artificial plants to determine the separate quantitative (density) and qualitative (shape) components of macrophyte structure on the prey-capture success of a predatory damselfly, Ischnura heterosticta tasmanica, and the southern pygmy perch, Nannoperca australis. Contrary to our expectations, macrophyte density had no effect on the prey-capture success of either predator, but both predators were significantly less effective in the structurally complex Myriophyllum analogue than in the structurally simpler Triglochin and Eleocharis analogues. Furthermore, the greater structural complexity of Myriophyllum amplified the impact of the negative interaction between the predators on prey numbers; the habitat use by damselfly larvae in response to the presence of southern pygmy perch meant they captured less prey in Myriophyllum. These results demonstrate habitat structure can influence multiple predator effects, and support the mechanism of increased prey refuge in more structurally complex macrophytes. JF - Oecologia AU - Warfe, D M AU - Barmuta, LA AD - School of Zoology and Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, GPO Box 252-05, 7001, Hobart, Tasmania, Australia, Danielle.Warfe@dpiwe.tas.gov.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 171 EP - 178 PB - Springer-Verlag VL - 141 IS - 1 SN - 0029-8549, 0029-8549 KW - Damselflies KW - Entomology Abstracts; Animal Behavior Abstracts; Ecology Abstracts KW - Myriophyllum KW - Ischnuridae KW - Triglochin KW - Habitat utilization KW - Nannoperca australis KW - Zygoptera KW - Odonata KW - Ischnura heterosticta tasmanica KW - Predator-prey interactions KW - Macrophytes KW - Freshwater ecosystems KW - Eleocharis KW - D 04659:Insects KW - Y 25503:Insects KW - Z 05199:Feeding UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18056604?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Oecologia&rft.atitle=Habitat+structural+complexity+mediates+the+foraging+success+of+multiple+predator+species&rft.au=Warfe%2C+D+M%3BBarmuta%2C+LA&rft.aulast=Warfe&rft.aufirst=D&rft.date=2004-09-01&rft.volume=141&rft.issue=1&rft.spage=171&rft.isbn=&rft.btitle=&rft.title=Oecologia&rft.issn=00298549&rft_id=info:doi/10.1007%2Fs00442-004-1644-x L2 - http://link.springer.de/link/service/journals/00442/bibs/4141001/41410171.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Ischnura heterosticta tasmanica; Odonata; Zygoptera; Ischnuridae; Myriophyllum; Nannoperca australis; Triglochin; Eleocharis; Predator-prey interactions; Macrophytes; Habitat utilization; Freshwater ecosystems DO - http://dx.doi.org/10.1007/s00442-004-1644-x ER - TY - JOUR T1 - Identification, characterisation and specificity of a cell wall lytic enzyme from Lactobacillus fermentum BR11 AN - 17757410; 6054117 AB - Screening of a genomic library with an antiserum raised against whole Lactobacillus fermentum BR11 cells identified a clone expressing an immunoreactive 37-kDa protein. Analysis of the 3010-bp DNA insert contained within the clone revealed four open reading frames (ORFs). One ORF encodes LysA, a 303 amino acid protein which has up to 35% identity with putative endolysins from prophages Lj928 and Lj965 from Lactobacillus johnsonii and Lp1 and Lp2 from Lactobacillus plantarum as well as with the endolysin of Lactobacillus gasseri bacteriophage Theta adh. The immunoreactive protein was shown to be encoded by a truncated ORF downstream of lysA which has similarity to glutamyl-tRNA synthetases. The N-terminus of LysA has sequence similarity with N-acetylmuramidase catalytic domains while the C-terminus has sequence similarity with putative cell envelope binding bacterial SH3b domains. C-terminal bacterial SH3b domains were identified in the majority of Lactobacillus bacteriophage endolysins. LysA was expressed in Escherichia coli and unusually was found to have a broad bacteriolytic activity range with activity against a number of different Lactobacillus species and against Lactococcus lactis, streptococci and Staphylococcus aureus. It was found that LysA is 2 and 8000 times more active against L. fermentum than L. lactis and Streptococcus pyogenes, respectively. JF - FEMS Microbiology Letters AU - Turner, Mark S AU - Hafner, Louise M AU - Walsh, Terry AU - Giffard, Philip M AD - Infectious Diseases Program, Faculty of Science, School of Life Sciences, Queensland University of Technology, G.P.O. Box 2434, Brisbane, Queensland 4001, Australia, ms.turner@qut.edu.au Y1 - 2004/09/01/ PY - 2004 DA - 2004 Sep 01 SP - 9 EP - 15 VL - 238 IS - 1 SN - 0378-1097, 0378-1097 KW - streptococci KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus KW - Phages KW - Lactococcus lactis KW - Lactobacillus johnsonii KW - Amino acids KW - Lactobacillus plantarum KW - Cell envelopes KW - C-Terminus KW - Prophages KW - N-Terminus KW - Lytic enzymes KW - Lactobacillus fermentum KW - Escherichia coli KW - DNA KW - Lactobacillus gasseri KW - Open reading frames KW - Cell walls KW - J 02728:Enzymes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17757410?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Microbiology+Letters&rft.atitle=Identification%2C+characterisation+and+specificity+of+a+cell+wall+lytic+enzyme+from+Lactobacillus+fermentum+BR11&rft.au=Turner%2C+Mark+S%3BHafner%2C+Louise+M%3BWalsh%2C+Terry%3BGiffard%2C+Philip+M&rft.aulast=Turner&rft.aufirst=Mark&rft.date=2004-09-01&rft.volume=238&rft.issue=1&rft.spage=9&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Letters&rft.issn=03781097&rft_id=info:doi/10.1016%2Fj.femsle.2004.07.008 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Lytic enzymes; Phages; Amino acids; Cell envelopes; C-Terminus; DNA; Prophages; Open reading frames; N-Terminus; Cell walls; Streptococcus; Lactococcus lactis; Lactobacillus fermentum; Lactobacillus johnsonii; Lactobacillus plantarum; Escherichia coli; Lactobacillus gasseri DO - http://dx.doi.org/10.1016/j.femsle.2004.07.008 ER - TY - JOUR T1 - Improved non-viral transfection of glial and adult neural stem cell lines and of primary astrocytes by combining agents with complementary modes of action AN - 17512195; 6397262 AB - Background Rational design of gene vectors for therapeutic applications requires understanding of transfection mechanisms. In this study, multiple transfection assays revealed complementary mechanisms between two commonly used transfection agents. This finding was then exploited to produce improved transfection outcomes. Methods and results Rat C6 glial cells, adult rat hippocampal progenitor cells and primary astrocytes were transfected using Lipofectamine (LA) or polyethylenimine (PEI), in vitro. Although LA- and PEI-transfected populations expressed the same total level of transgene product. LA transfected considerably more cells than PEI (approximately 20 vs. 14%). A fluorescently labelled plasmid and time-course analysis, involving both flow cytometry and confocal microscopy, were used to explain this apparent discrepancy. Results showed that LA delivered more plasmid DNA to the cytoplasm and achieved transgene expression in more cells than PEI. In contrast, PEI transfected fewer cells but, on average, produced more transgene product per transfected cell. Conclusions A comparative transfection model was developed to explain these different characteristics. According to this model, transfection is a multistage process with different transfection agents exerting their primary effect at different stages in this process. This model forecast that it should be possible to prepare a chimeric complex with a transfection efficiency that exceeded that achievable with Lipofectamine or polyethylenimine alone. This prediction was tested and shown to hold for glioma cells, primary astrocytes, and adult neural stems cells. JF - Journal of Gene Medicine AU - Tinsley, R B AU - Vesey, MJ AU - Barati, S AU - Rush, R A AU - Ferguson, IA AD - Department of Human Physiology, School of Medicine, Flinders University of South Australia, GPO Box 2100, Adelaide, Australia, i.ferguson@flinders.edu.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1023 EP - 1032 VL - 6 IS - 9 SN - 1099-498X, 1099-498X KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Astrocytes KW - Hippocampus KW - Glial cells KW - Animal models KW - Flow cytometry KW - Stem cells KW - Cytoplasm KW - Glioma KW - Neuronal-glial interactions KW - Neural stem cells KW - Plasmids KW - Brain tumors KW - Transfection KW - W3 33181:Gene therapy vectors KW - W 30965:Miscellaneous, Reviews KW - W4 120:Genetic Engineering in Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17512195?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Gene+Medicine&rft.atitle=Improved+non-viral+transfection+of+glial+and+adult+neural+stem+cell+lines+and+of+primary+astrocytes+by+combining+agents+with+complementary+modes+of+action&rft.au=Tinsley%2C+R+B%3BVesey%2C+MJ%3BBarati%2C+S%3BRush%2C+R+A%3BFerguson%2C+IA&rft.aulast=Tinsley&rft.aufirst=R&rft.date=2004-09-01&rft.volume=6&rft.issue=9&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=Journal+of+Gene+Medicine&rft.issn=1099498X&rft_id=info:doi/10.1002%2Fjgm.584 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Transfection; Animal models; Astrocytes; Plasmids; Neural stem cells; Stem cells; Neuronal-glial interactions; Hippocampus; Flow cytometry; Glial cells; Cytoplasm; Glioma; Brain tumors DO - http://dx.doi.org/10.1002/jgm.584 ER - TY - JOUR T1 - Atmospheric Dispersion of Gases and Odours from Animal Production Systems AN - 16181423; 6109228 AB - Animal production systems are major agricultural sources of the greenhouse gases, methane and nitrous oxide, of pollutants such as ammonia and hydrogen sulfide, and of odours. Verifying inventory estimates of their production, and monitoring, regulating and reducing their emission all require the ability to make precise, non-obtrusive measurements of their fluxes, and in the case of odours, an ability to predict concentrations close to the source. However, these requirements present special problems. The source areas are often small or irregularly shaped, the sources may be distributed heterogeneously, and emissions may be transient. Odours present an additional problem in that it is difficult to quantify their intensity since they are usually due to a mixture of more than 100 volatile organic compounds. The use of tracer gases to follow odour dispersion is discussed, but quantifying odour intensity is a pressing problem. The paper considers measurement techniques appropriate for sources of different shapes and sizes. Most attention is given to small and irregularly shaped sources for which conventional, large-area micrometeorological approaches are inapplicable: line-sources, strips, small plots, and waste storage areas such as ponds and manure piles. Mass balance techniques appear to be particularly useful for these purposes. Various applications of the methodology are considered in some detail. The advent of open-path gas lasers that can measure concentrations rapidly and over distances of hundreds of meters is seen as a significant development. Finally, the paper considers the use of a Lagrangian dispersion model that allows emissions from sources of any geometry to be linked to concentrations at any location downwind. In forward mode, it can predict downwind concentrations for given source scenarios, while in backward mode, it can infer fluxes from measurements of concentration and wind speed at just one height downwind. It is a very attractive tool for use in many dispersion problems relevant to the theme of the paper. JF - Journal of Agricultural Meteorology AU - Denmead, O T AD - CSIRO Land and Water, GPO Box 1666, Canberra, ACT 2601, Australia Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 163 EP - 171 VL - 60 IS - 3 SN - 0021-8588, 0021-8588 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Laser observation of atmospheric composition KW - Agricultural pollution KW - Nitrous oxide emission control KW - Pollution dispersion KW - Odors KW - Animal ecology KW - Emission inventories KW - Ammonia emissions KW - Meteorology KW - Lagrangian characteristics KW - Hydrogen sulfide emissions KW - Wind KW - Odor dispersal KW - Methane KW - Methane emission control KW - Ammonia KW - Hydrogen sulfide KW - Livestock KW - Air pollution KW - Gases KW - Greenhouse gases KW - Trace gases dispersion KW - Dispersion models KW - Gas dispersion KW - Volatile organic compounds KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - M2 551.586:Biometeorology and Bioclimatology (551.586) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16181423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Meteorology&rft.atitle=Atmospheric+Dispersion+of+Gases+and+Odours+from+Animal+Production+Systems&rft.au=Denmead%2C+O+T&rft.aulast=Denmead&rft.aufirst=O&rft.date=2004-09-01&rft.volume=60&rft.issue=3&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Meteorology&rft.issn=00218588&rft_id=info:doi/ LA - Japanese DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-02-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Methane emission control; Laser observation of atmospheric composition; Nitrous oxide emission control; Ammonia emissions; Lagrangian characteristics; Dispersion models; Trace gases dispersion; Animal ecology; Hydrogen sulfide emissions; Gas dispersion; Odor dispersal; Methane; Agricultural pollution; Ammonia; Pollution dispersion; Hydrogen sulfide; Odors; Livestock; Air pollution; Emission inventories; Gases; Meteorology; Greenhouse gases; Volatile organic compounds; Wind ER - TY - JOUR T1 - Arctic National Wildlife Refuge (ANWR): Controversies for the 108th Congress AN - 14721229; 10673299 AB - Advocates of energy development in the Arctic National Wildlife Refuge (ANWR), AK, argue that such activity would reduce US dependence on oil imports with detriment to the environment. Opponents contend that intrusion on this ecosystem can not be justified on any terms, and that any oil found would provide little energy security. The first relevant vote in the 108th Congress came in March 2003, when language was stripped from the Senate Budget resolution that would have facilitated subsequent passage of ANWR development legislation. There is little potential for enactment of ANWR development legislation in the remainder of the 108th Congress. JF - US Congressional Research Service Report IB10111 AU - Corn, MLynne AU - Gelb, Bernard A AU - Baldwin, Pamela Y1 - 2004/09// PY - 2004 DA - Sep 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - COST BENEFIT ANALYSIS, OIL KW - LEGISLATION, FEDERAL KW - WILDLIFE REFUGES, FEDERAL KW - LAND USE PLANNING KW - OIL EXPLORATION, ONSHORE KW - ALASKA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14721229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10111&rft.atitle=Arctic+National+Wildlife+Refuge+%28ANWR%29%3A+Controversies+for+the+108th+Congress&rft.au=Corn%2C+MLynne%3BGelb%2C+Bernard+A%3BBaldwin%2C+Pamela&rft.aulast=Corn&rft.aufirst=MLynne&rft.date=2004-09-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10111&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - COST BENEFIT ANALYSIS, OIL; OIL EXPLORATION, ONSHORE; LEGISLATION, FEDERAL; WILDLIFE REFUGES, FEDERAL; ALASKA; LAND USE PLANNING ER - TY - JOUR T1 - Exhaled Breath Condensate as a Suitable Matrix to Assess Lung Dose and Effects in Workers Exposed to Cobalt and Tungsten AN - 14712549; 10668143 AB - Workers from three factories producing either diamond tools or hard-metal inserts were studied to examine whether exhaled breath condensate (EBC) could be used to assess risk of exposure to pneumotoxic metals. The workers were exposed to either cobalt or tungsten. Two EBC and two urinary samples were collected from each subject, one before and one at the end of the work shift, and concentrations of Co, W, and malondialdehyde in EBC were measured. Malondialdehyde was measured as a biomarker of pulmonary oxidative stress. Results showed that Co and W could be measured in EBC. No correlation was found between either urinary Co or urinary W and malondialdehyde concentration in EBC, but both Co and W in EBC were correlated with EBC malondialdehyde levels, which suggested that exhaled elements reflected the lung dose. JF - Environmental Health Perspectives AU - Goldoni, Matteo AU - Catalani, Simona AU - De Palma, Giuseppe AU - Manini, Paola AU - Acampa, Olga AU - Corradi, Massimo AU - Bergonzi, Roberto Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1293 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - BIOLOGICAL INDICATORS, AIR KW - AIR POLLUTION, INDOOR KW - COBALT KW - TUNGSTEN KW - OXIDANT STRESS KW - ALDEHYDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14712549?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Exhaled+Breath+Condensate+as+a+Suitable+Matrix+to+Assess+Lung+Dose+and+Effects+in+Workers+Exposed+to+Cobalt+and+Tungsten&rft.au=Goldoni%2C+Matteo%3BCatalani%2C+Simona%3BDe+Palma%2C+Giuseppe%3BManini%2C+Paola%3BAcampa%2C+Olga%3BCorradi%2C+Massimo%3BBergonzi%2C+Roberto&rft.aulast=Goldoni&rft.aufirst=Matteo&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1293&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; BIOLOGICAL INDICATORS, AIR; AIR POLLUTION, INDOOR; OXIDANT STRESS; TUNGSTEN; COBALT; ALDEHYDES ER - TY - JOUR T1 - Particulate Matter Exposure Impairs Systemic Microvascular Endothelium-Dependent Dilation AN - 14710319; 10668144 AB - The effects of pulmonary particulate matter (PM) exposure on systemic endothelium-dependent arteriolar dilation were investigated using intratracheal instillation and bronchoalveolar lavage in conjunction with intravital microscopy, which were used to study the effects of residual oil flyash exposure on microvascular function in the rat spinotrapezius muscle. Arterioles of the first branching order were studied because the vessels are responsible, along with their upstream feed arteries, for approximately 60% of total spinotrapezius muscular vascular resistance. Results showed that pulmonary PM exposure significantly impaired A23187-induced arteriolar endothelium-dependent dilation in the rat spinotrapezius muscle. Pulmonary PM exposure appeared to abolish both nitric oxide-dependent and -independent systemic arteriolar dilation, but exposure did not affect systemic arteriolar smooth muscle responsiveness to NO. Particulate matter exposure increased the number of adhering and rolling leukocytes in spinotrapezius muscle venules. A significant impairment of systemic arteriolar dilation was observed 24 h after intratracheal instillation of 0.1 mg residual oil flyash. JF - Environmental Health Perspectives AU - Nurkiewicz, Timothy R AU - Porter, Dale W AU - Barger, Mark AU - Castranova, Vincent AU - Boegehold, Matthew A Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1299 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - FLYASH KW - PULMONARY EFFECTS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710319?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Particulate+Matter+Exposure+Impairs+Systemic+Microvascular+Endothelium-Dependent+Dilation&rft.au=Nurkiewicz%2C+Timothy+R%3BPorter%2C+Dale+W%3BBarger%2C+Mark%3BCastranova%2C+Vincent%3BBoegehold%2C+Matthew+A&rft.aulast=Nurkiewicz&rft.aufirst=Timothy&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1299&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; FLYASH; PULMONARY EFFECTS; PARTICULATES ER - TY - JOUR T1 - Pesticide Product Use and Risk of Non-Hodgkin Lymphoma in Women AN - 14707838; 10668140 JF - Environmental Health Perspectives AU - Kato, Ikuko AU - Watanabe-Meserve, Hiroko AU - Baptiste, Mark S AU - Lillquist, Patricia P AU - Frizzera, Galuco AU - Burke, Jerome S Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1275 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - PESTICIDE USAGE, RESIDENTIAL KW - PESTICIDE USAGE KW - DISEASES AND DISORDERS KW - NEW YORK STATE KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707838?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pesticide+Product+Use+and+Risk+of+Non-Hodgkin+Lymphoma+in+Women&rft.au=Kato%2C+Ikuko%3BWatanabe-Meserve%2C+Hiroko%3BBaptiste%2C+Mark+S%3BLillquist%2C+Patricia+P%3BFrizzera%2C+Galuco%3BBurke%2C+Jerome+S&rft.aulast=Kato&rft.aufirst=Ikuko&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1275&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; PESTICIDE USAGE, RESIDENTIAL; DISEASES AND DISORDERS; NEW YORK STATE; PESTICIDE EXPOSURE; PESTICIDE USAGE ER - TY - JOUR T1 - The Science and Practice of Carcinogen Identification and Evaluation AN - 14707762; 10668139 JF - Environmental Health Perspectives AU - Cogliano, Vincent James AU - Baan, Robert A AU - Straif, Kurt AU - Grosse, Yann AU - Secretan, Marie Beatrice AU - El Ghissassi, Fatiha AU - Kleihues, Paul Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1269 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - CARCINOGENIC MECHANISMS KW - CARCINOGENIC AGENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707762?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Large+Effects+from+Small+Exposures.+I.+Mechanisms+for+Endocrine-Disrupting+Chemicals+with+Estrogenic+Activity&rft.au=Welshons%2C+W+V%3BThayer%2C+KA%3BJudy%2C+B+M%3BTaylor%2C+JA%3BCurran%2C+E+M%3BVom+Saal%2C+FS&rft.aulast=Welshons&rft.aufirst=W&rft.date=2003-06-01&rft.volume=111&rft.issue=8&rft.spage=994&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.5494 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; CARCINOGENIC MECHANISMS; CARCINOGENIC AGENTS ER - TY - JOUR T1 - Neurologic Abnormalities in Workers of a 1-Bromopropane Factory AN - 14707462; 10668147 AB - Female workers in a 1-bromopropane production factory were examined in terms of neurologic function and other health related changes, and results were compared with those of control workers in a beer factory. Both factories were located in China. The medical examination, electrophysiologic studies, blood tests, and neurobehavioral tests conducted are detailed, along with the assessment of exposure to 1-bromopropane. Results showed that 1-bromopropane workers had significantly longer distal latency and lower sensory nerve conduction velocity than did age-matched controls. Neurobehavioral tests showed lower values for the forward and backward digit span, Benton visual memory test, pursuit aiming test, and Profile of Mood States test in the 1-bromopropane-exposed workers than in controls. JF - Environmental Health Perspectives AU - Ichihara, Gaku AU - Li, Weihua AU - Shibata, Eiji AU - Ding, Xuncheng AU - Wang, Hailan AU - Liang, Yideng AU - Peng, Simeng Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1319 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEALTH SAFETY, OCCUPATIONAL KW - SOLVENTS KW - NEUROTOXICITY KW - AIR POLLUTION, INDOOR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Neurologic+Abnormalities+in+Workers+of+a+1-Bromopropane+Factory&rft.au=Ichihara%2C+Gaku%3BLi%2C+Weihua%3BShibata%2C+Eiji%3BDing%2C+Xuncheng%3BWang%2C+Hailan%3BLiang%2C+Yideng%3BPeng%2C+Simeng&rft.aulast=Ichihara&rft.aufirst=Gaku&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1319&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOLVENTS; HEALTH SAFETY, OCCUPATIONAL; NEUROTOXICITY; AIR POLLUTION, INDOOR ER - TY - JOUR T1 - Effects of Low Sulfur Fuel and a Catalyzed Particle Trap on the Composition and Toxicity of Diesel Emissions AN - 14707413; 10668145 AB - Young C57B1/6 mice were exposed to diesel engine exhaust (DEE) or to DEE plus an emission-reduction method involving low-sulfur fuel and a catalyzed particle trap to assess the impact of such emission-reduction methods on the composition and toxicity of diesel emissions. Implementation of the low-S fuel/catalyzed trap combination decreased the concentrations of most components of emissions and diminished the biological effects of DEE on viral clearance, inflammation, and oxidative stress. The control method decreased nearly every measured exposure constituent, except for nitrogen oxides and selected individual organic compounds such as carbonyls, to background levels. JF - Environmental Health Perspectives AU - McDonald, Jacob D AU - Harrod, Kevin S AU - Seagrave, JeanClare AU - Seilkop, Steven K AU - Mauderly, Joe L Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 1307 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 13 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DIESEL ENGINES KW - AUTOMOBILE EMISSIONS KW - FUEL CHEMISTRY KW - PARTICULATES KW - IMMUNE RESPONSE KW - PULMONARY EFFECTS KW - OXIDANT STRESS KW - AUTOMOBILE EMISSION CONTROL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+Low+Sulfur+Fuel+and+a+Catalyzed+Particle+Trap+on+the+Composition+and+Toxicity+of+Diesel+Emissions&rft.au=McDonald%2C+Jacob+D%3BHarrod%2C+Kevin+S%3BSeagrave%2C+JeanClare%3BSeilkop%2C+Steven+K%3BMauderly%2C+Joe+L&rft.aulast=McDonald&rft.aufirst=Jacob&rft.date=2004-09-01&rft.volume=112&rft.issue=13&rft.spage=1307&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DIESEL ENGINES; FUEL CHEMISTRY; AUTOMOBILE EMISSIONS; OXIDANT STRESS; PULMONARY EFFECTS; AUTOMOBILE EMISSION CONTROL; PARTICULATES; IMMUNE RESPONSE ER - TY - JOUR T1 - Options for Managing Invasive Marine Species AN - 1034812789; 17024092 AB - Marine biological invasions are increasingly recognised as a threat to biodiversity and coastal industry, including fisheries. Globally, efforts are underway to contain, if not eradicate, several high-impact marine invasive species. However, working in a marine environment places unique social, political and technical constraints on options for pest control, which we explored in a series of stakeholder workshops. Results suggest that current efforts are low risk and publicly acceptable, but have a low probability of success against established invaders. However, techniques deemed likely to be successful and ultimately needed in a marine context are currently more contentious for social and political reasons. To control introduced marine pests, scientists and managers will need to overcome perceptual biases among marine stakeholders, develop a decision-making framework for what is perceived to be an open system, and focus on technologies likely to be both effective and publicly and politically acceptable. JF - Biological Invasions AU - Thresher, Ronald E AU - Kuris, Armand M AD - CSIRO Marine Research, G.P.O. Box 1538, Hobart, Tasmania, 7001, Australia, Ron.Thresher@csiro.au Y1 - 2004/09// PY - 2004 DA - Sep 2004 SP - 295 EP - 300 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 6 IS - 3 SN - 1387-3547, 1387-3547 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Marine fisheries KW - Stakeholders KW - Politics KW - Biological diversity KW - Biodiversity KW - Fishery management KW - Marine environment KW - Risk factors KW - Fisheries KW - Invasions KW - Pests KW - Marine KW - Conferences KW - Invasive Species KW - Pest control KW - Rare species KW - Decision making KW - Perception KW - Nature conservation KW - Introduced species KW - Open systems KW - Technology KW - O 5080:Legal/Governmental KW - M3 1010:Issues in Sustainable Development KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034812789?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Invasions&rft.atitle=Options+for+Managing+Invasive+Marine+Species&rft.au=Thresher%2C+Ronald+E%3BKuris%2C+Armand+M&rft.aulast=Thresher&rft.aufirst=Ronald&rft.date=2004-09-01&rft.volume=6&rft.issue=3&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=Biological+Invasions&rft.issn=13873547&rft_id=info:doi/10.1023%2FB%3ABINV.0000034598.28718.2e LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - Marine fisheries; Fishery management; Invasive Species; Nature conservation; Biodiversity; Pest control; Rare species; Open systems; Introduced species; Decision making; Conferences; Marine environment; Risk factors; Fisheries; Invasions; Pests; Stakeholders; Perception; Politics; Biological diversity; Technology; Marine DO - http://dx.doi.org/10.1023/B:BINV.0000034598.28718.2e ER - TY - BOOK T1 - Environmental cleanup at Vieques Island and Culebra Island T2 - Mem. AN - 59964367; 2004-1003800 AB - Analyzes key issues regarding the cleanup of environmental contamination resulting from weapons training and other activities of the US Navy. JF - United States Congressional Research Service, August 19 2004. AU - Rearden, David M AU - Luther, Linda G Y1 - 2004/08/19/ PY - 2004 DA - 2004 Aug 19 PB - United States Congressional Research Service KW - United States -- Navy KW - Naval bases -- United States KW - Military training -- United States KW - Ordnance testing -- United States KW - Munitions -- United States KW - Vieques (island), Puerto Rico -- Environmental conditions KW - Environmental health -- Puerto Rico KW - Culebra (island), Puerto Rico -- Environmental conditions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59964367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Rearden%2C+David+M%3BLuther%2C+Linda+G&rft.aulast=Rearden&rft.aufirst=David&rft.date=2004-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Environmental+cleanup+at+Vieques+Island+and+Culebra+Island&rft.title=Environmental+cleanup+at+Vieques+Island+and+Culebra+Island&rft.issn=&rft_id=info:doi/ L2 - http://www.house.gov/serrano/pdf/vieques-culebra.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Cong Research Service N1 - Document feature - map(s), table(s) N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - CemaT1 is an active transposon within the Caenorhabditis elegans genome. AN - 66774103; 15302406 AB - The maT clade of transposons is a group of transposable elements intermediate in sequence and predicted protein structure to mariner and Tc transposons, with a distribution thus far limited to a few invertebrate species. In the nematode Caenorhabditis elegans, there are eight copies of CemaT1 that are predicted to encode a functional transposase, with five copies being >99% identical. We present evidence, based on searches of publicly available databases and on PCR-based mobility assays, that the CemaT1 transposase is expressed in C. elegans and that the CemaT transposons are capable of excising in both somatic and germline tissues. We also show that the frequency of CemaT1 excisions within the genome of the N2 strain of C. elegans is comparable to that of the Tc1 transposon. However, unlike Tc transposons in mutator strains of C. elegans, maT transposons do not exhibit increased frequencies of mobility, suggesting that maT is not regulated by the same factors that control Tc activity in these strains. Finally, we show that CemaT1 transposons are capable of precise transpositions as well as orientation inversions at some loci, and thereby become members of an increasing number of identified active transposons within the C. elegans genome. JF - Gene AU - Brownlie, J C AU - Whyard, S AD - Division of Entomology, CSIRO GPO Box 1700, Canberra ACT 2601, Australia. j.brownlie@uq.edu.au Y1 - 2004/08/18/ PY - 2004 DA - 2004 Aug 18 SP - 55 EP - 64 VL - 338 IS - 1 SN - 0378-1119, 0378-1119 KW - DNA Transposable Elements KW - 0 KW - Index Medicus KW - Animals KW - Base Sequence KW - Gene Expression KW - Germ-Line Mutation KW - Species Specificity KW - Mutation KW - Mutagenesis, Insertional KW - DNA Transposable Elements -- genetics KW - Genome KW - Caenorhabditis elegans -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66774103?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Gene&rft.atitle=CemaT1+is+an+active+transposon+within+the+Caenorhabditis+elegans+genome.&rft.au=Brownlie%2C+J+C%3BWhyard%2C+S&rft.aulast=Brownlie&rft.aufirst=J&rft.date=2004-08-18&rft.volume=338&rft.issue=1&rft.spage=55&rft.isbn=&rft.btitle=&rft.title=Gene&rft.issn=03781119&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-02 N1 - Date created - 2004-08-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - BOOK T1 - Abortion services and military medical facilities T2 - CRS rept. for Cong. Order code 95-387 F AN - 59931208; 2004-1008690 AB - Describes history of provisions to abortion services for military personnel and their dependents, and other military health care beneficiaries, with an emphasis on legislative actions; proposals to modify the law and related legislative and administrative actions; US. JF - United States Congressional Research Service, August 18 2004. AU - Burrelli, David f Y1 - 2004/08/18/ PY - 2004 DA - 2004 Aug 18 PB - United States Congressional Research Service KW - United States -- Armed forces -- Medical and sanitary affairs KW - Medicine, Military -- United States KW - Medical service -- Legal aspects KW - Abortion -- Regulation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59931208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Burrelli%2C+David+f&rft.aulast=Burrelli&rft.aufirst=David&rft.date=2004-08-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Abortion+services+and+military+medical+facilities&rft.title=Abortion+services+and+military+medical+facilities&rft.issn=&rft_id=info:doi/ L2 - http://www.law.umaryland.edu/marshall/ElectronicResources/crsreports/crsdocuments/95-387_F.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Cong Research Service N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Peak resolution and tailing in alpha-particle spectrometry for environmental samples. AN - 71996840; 15177338 AB - Peak resolution in alpha-particle spectrometry is generally quoted as full-width-at half maximum. However, the extent of tailing of alpha particle peaks into regions of lower energy is often a critical factor for accurate spectral analysis, particularly given the relatively low count rates observed for many environmental samples. In this paper we examine the influence of various factors on peak resolution and tailing for spectra collected using solid-state alpha detectors, in particular chamber gas pressure and source deposit thickness. JF - Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine AU - Martin, Paul AU - Hancock, Gary J AD - Environmental Research Institute of the Supervising Scientist, GPO Box 461, Darwin 0801, Australia. paul.martin@deh.gov.au PY - 2004 SP - 161 EP - 165 VL - 61 IS - 2-3 SN - 0969-8043, 0969-8043 KW - Environmental Pollutants KW - 0 KW - Radioisotopes KW - Index Medicus KW - Sensitivity and Specificity KW - Reproducibility of Results KW - Particle Size KW - Pressure KW - Artifacts KW - Radioisotopes -- chemistry KW - Spectrum Analysis -- methods KW - Alpha Particles KW - Radioisotopes -- analysis KW - Environmental Pollutants -- analysis KW - Radiometry -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71996840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+radiation+and+isotopes+%3A+including+data%2C+instrumentation+and+methods+for+use+in+agriculture%2C+industry+and+medicine&rft.atitle=Peak+resolution+and+tailing+in+alpha-particle+spectrometry+for+environmental+samples.&rft.au=Windham%2C+Gayle+C%3BWaller%2C+Kirsten%3BAnderson%2C+Meredith%3BFenster%2C+Laura%3BMendola%2C+Pauline%3BSwan%2C+Shanna&rft.aulast=Windham&rft.aufirst=Gayle&rft.date=2003-06-01&rft.volume=111&rft.issue=7&rft.spage=935&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-16 N1 - Date created - 2004-06-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - [Methods for protein purification from biological samples]. AN - 66889508; 15376965 JF - Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme AU - Araki, Norie AD - nori@gpo.kumamoto-u.ac.jp Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 1495 EP - 1505 VL - 49 IS - 11 Suppl SN - 0039-9450, 0039-9450 KW - Hazardous Substances KW - 0 KW - Proteins KW - Index Medicus KW - Sequence Analysis, Protein -- methods KW - Animals KW - Mass Spectrometry -- instrumentation KW - Electrophoresis -- methods KW - Humans KW - Mass Spectrometry -- methods KW - Chromatography -- methods KW - Sequence Analysis, Protein -- instrumentation KW - Proteins -- isolation & purification KW - Specimen Handling -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66889508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tanpakushitsu+kakusan+koso.+Protein%2C+nucleic+acid%2C+enzyme&rft.atitle=%5BMethods+for+protein+purification+from+biological+samples%5D.&rft.au=Araki%2C+Norie&rft.aulast=Araki&rft.aufirst=Norie&rft.date=2004-08-01&rft.volume=49&rft.issue=11+Suppl&rft.spage=1495&rft.isbn=&rft.btitle=&rft.title=Tanpakushitsu+kakusan+koso.+Protein%2C+nucleic+acid%2C+enzyme&rft.issn=00399450&rft_id=info:doi/ LA - Japanese DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-02 N1 - Date created - 2004-09-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Clonidine prolongation of lidocaine analgesia after sciatic nerve block in rats Is mediated via the hyperpolarization-activated cation current, not by alpha-adrenoreceptors. AN - 66743959; 15277933 AB - Although clonidine is commonly combined with local anesthetics to extend duration of peripheral nerve block, the mechanism by which clonidine potentiates local anesthetic action in vivo is unclear. Male Sprague-Dawley rats received percutaneous injections of 1% lidocaine with/without clonidine or epinephrine into the sciatic notch and duration of sensory blockade was quantified by inhibition of pinprick foot withdrawal. The antagonists prazosin or yohimbine were injected before lidocaine with clonidine or epinephrine to determine the role of alpha-adrenergic receptors. The role of the hyperpolarization-activated cation current (Ih) was evaluated by injecting the current blocker ZD 7288 as well as the current enhancers forskolin and 8-Br-cAMP before lidocaine alone or with 15 micrograms/ml clonidine. Mean duration of sensory block for lidocaine alone was 69 +/- 2 min. Sensory block duration increased monotonically with increasing doses of added clonidine or epinephrine. Preinjection of prazosin but not yohimbine prevented the increase in block duration seen with epinephrine. Neither alpha-adrenergic antagonist attenuated the extended duration of block with clonidine. ZD 7288 extended sensory blockade equivalent to the prolongation observed with clonidine. There was no additive effect when ZD 7288 and clonidine were combined, and a decreased duration of nerve block when either forskolin or 8-Br-cAMP preceded injection of lidocaine with clonidine. The findings indicate that prolongation of duration of in vivo lidocaine nerve blockade by clonidine is not mediated by an alpha-adrenergic mechanism but likely involves the Ih current. JF - Anesthesiology AU - Kroin, Jeffrey S AU - Buvanendran, Asokumar AU - Beck, Daniel R AU - Topic, Julie E AU - Watts, Daniel E AU - Tuman, Kenneth J AD - Department of Anesthesiology, Rush Medical College, 1653 W. Congress Parkway, Chicago, Illinois 60612, USA. jkroin@rush.edu Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 488 EP - 494 VL - 101 IS - 2 SN - 0003-3022, 0003-3022 KW - Adrenergic alpha-Agonists KW - 0 KW - Anesthetics, Local KW - Ion Channels KW - Pyrimidines KW - Receptors, Adrenergic, alpha KW - ICI D2788 KW - 133059-99-1 KW - Colforsin KW - 1F7A44V6OU KW - Lidocaine KW - 98PI200987 KW - Clonidine KW - MN3L5RMN02 KW - Epinephrine KW - YKH834O4BH KW - Abridged Index Medicus KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Colforsin -- pharmacology KW - Dose-Response Relationship, Drug KW - Epinephrine -- pharmacology KW - In Vitro Techniques KW - Receptors, Adrenergic, alpha -- drug effects KW - Pyrimidines -- pharmacology KW - Drug Synergism KW - Male KW - Lidocaine -- administration & dosage KW - Anesthetics, Local -- administration & dosage KW - Nerve Block KW - Ion Channels -- antagonists & inhibitors KW - Anesthetics, Local -- pharmacology KW - Adrenergic alpha-Agonists -- pharmacology KW - Clonidine -- administration & dosage KW - Adrenergic alpha-Agonists -- administration & dosage KW - Lidocaine -- pharmacology KW - Clonidine -- pharmacology KW - Sciatic Nerve -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66743959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Anesthesiology&rft.atitle=Clonidine+prolongation+of+lidocaine+analgesia+after+sciatic+nerve+block+in+rats+Is+mediated+via+the+hyperpolarization-activated+cation+current%2C+not+by+alpha-adrenoreceptors.&rft.au=Kroin%2C+Jeffrey+S%3BBuvanendran%2C+Asokumar%3BBeck%2C+Daniel+R%3BTopic%2C+Julie+E%3BWatts%2C+Daniel+E%3BTuman%2C+Kenneth+J&rft.aulast=Kroin&rft.aufirst=Jeffrey&rft.date=2004-08-01&rft.volume=101&rft.issue=2&rft.spage=488&rft.isbn=&rft.btitle=&rft.title=Anesthesiology&rft.issn=00033022&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-24 N1 - Date created - 2004-07-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Coenzyme Q10 and diabetic endotheliopathy: oxidative stress and the 'recoupling hypothesis'. AN - 66715906; 15256611 AB - Increased oxidative stress in diabetes mellitus may underlie the development of endothelial cell dysfunction by decreasing the availability of nitric oxide (NO) as well as by activating pro-inflammatory pathways. In the arterial wall, redox imbalance and oxidation of tetrahydrobiopterin (BH4) uncouples endothelial nitric oxide synthase (eNOS). This results in decreased production and increased consumption of NO, and generation of free radicals, such as superoxide and peroxynitrite. In the mitochondria, increased redox potential uncouples oxidative phosphorylation, resulting in inhibition of electron transport and increased transfer of electrons to molecular oxygen to form superoxide and other oxidant radicals. Coenzyme Q10 (CoQ), a potent antioxidant and a critical intermediate of the electron transport chain, may improve endothelial dysfunction by 'recoupling' eNOS and mitochondrial oxidative phosphorylation. CoQ supplementation may also act synergistically with anti-atherogenic agents, such as fibrates and statins, to improve endotheliopathy in diabetes. JF - QJM : monthly journal of the Association of Physicians AU - Chew, G T AU - Watts, G F AD - School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, GPO Box X2213, Perth, Western Australia, Australia 6847. Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 537 EP - 548 VL - 97 IS - 8 SN - 1460-2725, 1460-2725 KW - Antioxidants KW - 0 KW - Coenzymes KW - Receptors, Cytoplasmic and Nuclear KW - Transcription Factors KW - Ubiquinone KW - 1339-63-5 KW - Nitric Oxide KW - 31C4KY9ESH KW - NOS3 protein, human KW - EC 1.14.13.39 KW - Nitric Oxide Synthase KW - Nitric Oxide Synthase Type III KW - coenzyme Q10 KW - EJ27X76M46 KW - Index Medicus KW - Endothelium, Vascular -- enzymology KW - Transcription Factors -- metabolism KW - Humans KW - Diabetic Angiopathies -- enzymology KW - Antioxidants -- metabolism KW - Phosphorylation KW - Receptors, Cytoplasmic and Nuclear -- metabolism KW - Diabetic Angiopathies -- drug therapy KW - Mitochondria -- metabolism KW - Dietary Supplements KW - Drug Synergism KW - Diabetic Angiopathies -- prevention & control KW - Diabetes Mellitus, Type 2 -- drug therapy KW - Ubiquinone -- administration & dosage KW - Oxidative Stress -- physiology KW - Diabetes Mellitus, Type 2 -- enzymology KW - Ubiquinone -- metabolism KW - Nitric Oxide -- metabolism KW - Nitric Oxide Synthase -- metabolism KW - Diabetes Mellitus, Type 2 -- prevention & control KW - Ubiquinone -- analogs & derivatives UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66715906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=QJM+%3A+monthly+journal+of+the+Association+of+Physicians&rft.atitle=Coenzyme+Q10+and+diabetic+endotheliopathy%3A+oxidative+stress+and+the+%27recoupling+hypothesis%27.&rft.au=Chew%2C+G+T%3BWatts%2C+G+F&rft.aulast=Chew&rft.aufirst=G&rft.date=2004-08-01&rft.volume=97&rft.issue=8&rft.spage=537&rft.isbn=&rft.btitle=&rft.title=QJM+%3A+monthly+journal+of+the+Association+of+Physicians&rft.issn=14602725&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-16 N1 - Date created - 2004-07-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Acetylation of raw cotton for oil spill cleanup application: an FTIR and 13C MAS NMR spectroscopic investigation. AN - 66705676; 15249021 AB - Fourier transform infrared (FTIR) and 13C MAS NMR spectroscopy have been used to investigate the acetylation of raw cotton samples with acetic anhydride without solvents in the presence of different amounts of 4-dimethylaminopyridine (DMAP) catalyst. This is a continuation of our previous investigation of acetylation of commercial cotton in an effort to develop hydrophobic, biodegradable, cellulosic sorbent materials for cleaning up oil spills. The FTIR data have again provided a clear evidence for successful acetylation. The NMR results further confirm the successful acetylation. The extent of acetylation was quantitatively determined using the weight percent gain (WPG) due to acetylation and by calculating the ratio R between the intensity of the acetyl C=O stretching band at 1740-1745 cm(-1) and the intensity of C-O stretching vibration of the cellulose backbone at about 1020-1040 cm(-1). The FTIR technique was found to be highly sensitive and reliable for the determination of the extent of acetylation. The level of acetylation of the raw cotton samples was found to be much higher than that of cotton fabrics and the previously studied commercial cotton. The variation of the R and WPG with reaction time, amount of DMAP catalyst and different samples of raw cotton is discussed. JF - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy AU - Adebajo, Moses O AU - Frost, Ray L AD - Inorganic Materials Research Program, School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane Qld 4001, Australia. m.adebajo@qut.edu.au Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 2315 EP - 2321 VL - 60 IS - 10 SN - 1386-1425, 1386-1425 KW - Acetic Anhydrides KW - 0 KW - Carbon Isotopes KW - Petroleum KW - Water Pollutants, Chemical KW - acetic anhydride KW - 2E48G1QI9Q KW - 4-Aminopyridine KW - BH3B64OKL9 KW - 4-dimethylaminopyridine KW - PFP1R6P0S8 KW - Index Medicus KW - Spectroscopy, Fourier Transform Infrared KW - Acetylation KW - Magnetic Resonance Spectroscopy KW - Acetic Anhydrides -- chemistry KW - 4-Aminopyridine -- chemistry KW - 4-Aminopyridine -- analogs & derivatives KW - Cotton Fiber UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66705676?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.atitle=Acetylation+of+raw+cotton+for+oil+spill+cleanup+application%3A+an+FTIR+and+13C+MAS+NMR+spectroscopic+investigation.&rft.au=Adebajo%2C+Moses+O%3BFrost%2C+Ray+L&rft.aulast=Adebajo&rft.aufirst=Moses&rft.date=2004-08-01&rft.volume=60&rft.issue=10&rft.spage=2315&rft.isbn=&rft.btitle=&rft.title=Spectrochimica+acta.+Part+A%2C+Molecular+and+biomolecular+spectroscopy&rft.issn=13861425&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-03-01 N1 - Date created - 2004-07-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hemispheric correlation with psychomotor learning in manual communication tasks TT - Correlacion entre hemisfericidad y el aprendisaje psicomotor en lastareas de comunicaion cestual AN - 20966805; 7301949 AB - The objective of this study was to establish a correlation between hemispheres andthe psychomotor learning in connection with the gesture communication. According to Moura (1993), when the gesture communication is practiced, especially in the Brazilian Sign Language (LIBRAS), each of the brain hemispheres of the listening person reveals a decode predominantly different Therefore, left hemisphere prevails the linguistic functions, and right hemisphere the space-vision. In this survey we had the participation of one hundred students of both sexes, between 15 and 17 years old, with high school level attending one private school in the city of Rio de Janeiro. Once selected, the group was submitted to the CLEM TEST to identify the preference of the hemisphere processing. The students were divided in three hemispheric groups, that is, the right hemisphere (HR), the left hemisphere (HL) and the bi-hemispheres (HRL).The components of each group were then submitted to a individual selective test including significative competency in relation to the communicative gestures signs. Analysis of variance was performed between the three groups (p < 0,05). The especific sign, regarding the performance of each student, indicated evidences that the linguistics aspects are preferably processed in the left hemisphere. JF - Fitness and Performance Journal AU - Vallado, SY AU - de Delgado, GPO AU - de Souza, DOR AU - Guagliardi, Jr AU - da Silva, VF AU - Lins, FRW AD - Rua Rainha Guilhermina, 131, apto. 305 - Leblon - Rio de Janeiro - Cep 22441-120, soniavallado@ig.com.br Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 207 EP - 210 VL - 3 IS - 4 SN - 1519-9088, 1519-9088 KW - Physical Education Index; CSA Neurosciences Abstracts KW - High school students KW - Fitness KW - Hemispheric laterality KW - Learning KW - Cerebral hemispheres KW - Communication KW - Brain KW - Surveys KW - Private schools KW - Participation KW - Analysis KW - Language KW - Performance KW - Sex KW - N3 11001:Behavioral and Cognitive Neuroscience KW - PE 080:Motor Learning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20966805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fitness+and+Performance+Journal&rft.atitle=Hemispheric+correlation+with+psychomotor+learning+in+manual+communication+tasks&rft.au=Vallado%2C+SY%3Bde+Delgado%2C+GPO%3Bde+Souza%2C+DOR%3BGuagliardi%2C+Jr%3Bda+Silva%2C+VF%3BLins%2C+FRW&rft.aulast=Vallado&rft.aufirst=SY&rft.date=2004-08-01&rft.volume=3&rft.issue=4&rft.spage=207&rft.isbn=&rft.btitle=&rft.title=Fitness+and+Performance+Journal&rft.issn=15199088&rft_id=info:doi/ LA - Portuguese DB - Physical Education Index N1 - Date revised - 2007-04-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Fitness; High school students; Learning; Private schools; Participation; Analysis; Brain; Communication; Surveys; Performance; Sex; Hemispheric laterality; Cerebral hemispheres; Language ER - TY - JOUR T1 - Nutrients for Cognitive Development in School-aged Children AN - 20411306; 9084802 AB - This review considers the research to date on the role of nutrition in cognitive development in children, with a particular emphasis on the relatively neglected post-infancy period. Undernutrition and deficiencies of iodine, iron, and folate are all important for the development of the brain and the emergent cognitive functions, and there is some evidence to suggest that zinc, vitamin B12, and omega-3 polyunsaturated fatty acids may also be important. Considerations for future research include a focus on the interactions between micronutrients and macronutrients that might be influential in the optimization of cognitive development; investigation of the impact of nutritional factors in children after infancy, with particular emphasis on effects on the developing executive functions; and selection of populations that might benefit from nutritional interventions, for example, children with nutrient deficiencies or those suffering from attention deficit-hyperactivity disorder and dyslexia. JF - Nutrition Reviews AU - Janet, Bryan AU - Saskia, Osendarp AU - Donna, Hughes AU - Eva, Calvaresi AU - Katrine, Baghurst AU - Jan-Willem, van Klinken AD - CSIRO, Health Sciences and Nutrition, GPO Box 10041, Adelaide BC, South Australia, 5000 Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 295 EP - 306 PB - International Life Sciences Institute, PO Box 1897 Lawrence KS 66044-8897 USA, [mailto:ilsi@ilsi.org], [URL:http://www.ilsi.org] VL - 62 IS - 8 SN - 0029-6643, 0029-6643 KW - Pollution Abstracts; CSA Neurosciences Abstracts KW - NUTRITION KW - COGNITION KW - CHILDREN KW - MICRONUTRIENTS KW - BRAIN DEVELOPMENT KW - Undernutrition KW - Nutrients KW - polyunsaturated fatty acids KW - Nutrition KW - vitamins KW - intervention KW - Zinc KW - Iodine KW - Micronutrients KW - Folic acid KW - micronutrients KW - Brain KW - Dyslexia KW - Children KW - Executive function KW - nutrients KW - Nutrient deficiency KW - cognitive ability KW - Vitamin B12 KW - Cognitive ability KW - Reviews KW - nutrient deficiency KW - Polyunsaturated fatty acids KW - Attention KW - Iron KW - N3 11001:Behavioral and Cognitive Neuroscience KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20411306?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nutrition+Reviews&rft.atitle=Nutrients+for+Cognitive+Development+in+School-aged+Children&rft.au=Janet%2C+Bryan%3BSaskia%2C+Osendarp%3BDonna%2C+Hughes%3BEva%2C+Calvaresi%3BKatrine%2C+Baghurst%3BJan-Willem%2C+van+Klinken&rft.aulast=Janet&rft.aufirst=Bryan&rft.date=2004-08-01&rft.volume=62&rft.issue=8&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=Nutrition+Reviews&rft.issn=00296643&rft_id=info:doi/10.1301%2Fnr.2004.aug.295-306 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-03-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Undernutrition; Brain; Dyslexia; Nutrients; Children; Nutrition; Executive function; Nutrient deficiency; Vitamin B12; Cognitive ability; Zinc; Iodine; Polyunsaturated fatty acids; Micronutrients; Folic acid; Iron; Attention; micronutrients; polyunsaturated fatty acids; nutrients; vitamins; cognitive ability; Reviews; intervention; nutrient deficiency DO - http://dx.doi.org/10.1301/nr.2004.aug.295-306 ER - TY - JOUR T1 - Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coli AN - 20193390; 5970646 JF - Analytical Biochemistry AU - Uchimura, Y AU - Nakamura, M AU - Sugasawa, K AU - Nakao, M AU - Saitoh, H AD - Department of Regeneration Medicine, Institute of Molecular Embryology Genetics, Kumamoto University, Kumamoto, 860-0811, Japan, hisa@gpo.kumamoto-u.ac.jp Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 204 EP - 206 PB - Academic Press, Inc., 525 B St. Ste. 1900 San Diego CA 92101-4495 USA, [mailto:apsubs@acad.com] VL - 331 IS - 1 SN - 0003-2697, 0003-2697 KW - Microbiology Abstracts B: Bacteriology KW - Biochemistry KW - Escherichia coli KW - J 02490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20193390?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+Biochemistry&rft.atitle=Overproduction+of+eukaryotic+SUMO-1-+and+SUMO-2-conjugated+proteins+in+Escherichia+coli&rft.au=Uchimura%2C+Y%3BNakamura%2C+M%3BSugasawa%2C+K%3BNakao%2C+M%3BSaitoh%2C+H&rft.aulast=Uchimura&rft.aufirst=Y&rft.date=2004-08-01&rft.volume=331&rft.issue=1&rft.spage=204&rft.isbn=&rft.btitle=&rft.title=Analytical+Biochemistry&rft.issn=00032697&rft_id=info:doi/10.1016%2Fj.ab.2004.04.034 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Biochemistry; Escherichia coli DO - http://dx.doi.org/10.1016/j.ab.2004.04.034 ER - TY - JOUR T1 - Framework for soil suitability evaluation for sewage effluent renovation AN - 19933232; 6018958 AB - Current methods of establishing suitable locations for onsite wastewater treatment systems (OWTS) are inadequate, particularly in light of the numerous cases of onsite system failure and the resulting adverse consequences. The development of a soil suitability framework for assessing soil suitability for OWTS allows a more practical means of assessment. The use of multivariate statistical analysis techniques, including Principal Component Analysis (PCA) and multi-criteria decision aids of PROMETHEE and GAIA, enabled the identification of suitable soils for effluent renovation. The outcome of the multivariate analysis, together with soil permeability and drainage characteristics permitted the establishment of a framework for assessing soil suitability based on three main soil functions: (1) the ability of the soil to provide suitable effluent renovation, (2) the permeability of the soil, and (3) the soil's drainage characteristics. The developed framework was subsequently applied to the research area, Gold Coast, Queensland, Australia, and the use of standard scoring functions were utilised to provide a scoring system to signify which soils were more suitable for effluent renovation processes. From the assessment, it was found that Chromosol and Kurosol soils provided the highest level of effluent renovation, closely followed by Ferrosol and Dermosol, Kandosol and Rudosol soil types. Tennosol and Podosol soil types were found to have a significantly lower suitability, with Hydrosol soils proving the least suitable for renovating effluent from OWTS. JF - Environmental Geology AU - Carroll, S AU - Goonetilleke, A AU - Dawes, L AD - School of Civil Engineering, Queensland University of Technology, GPO Box 2434, 4001, Brisbane, Australia, s.carroll@qut.edu.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 195 EP - 208 PB - Springer-Verlag VL - 46 IS - 2 SN - 0943-0105, 0943-0105 KW - Water Resources Abstracts KW - Land Disposal KW - Drainage KW - Principal Component Analysis KW - Effluents KW - Multivariate Analysis KW - Evaluation KW - Permeability KW - Assessments KW - Australia, Queensland, Gold Coast KW - Statistical Analysis KW - Soil Types KW - Wastewater Disposal KW - Standards KW - Wastewater Treatment KW - Coasts KW - SW 3040:Wastewater treatment processes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19933232?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Geology&rft.atitle=Framework+for+soil+suitability+evaluation+for+sewage+effluent+renovation&rft.au=Carroll%2C+S%3BGoonetilleke%2C+A%3BDawes%2C+L&rft.aulast=Carroll&rft.aufirst=S&rft.date=2004-08-01&rft.volume=46&rft.issue=2&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Environmental+Geology&rft.issn=09430105&rft_id=info:doi/10.1007%2Fs00254-004-1026-z L2 - http://link.springer.de/link/service/journals/00254/bibs/4046002/40460195.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-11-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Drainage; Land Disposal; Principal Component Analysis; Effluents; Multivariate Analysis; Evaluation; Permeability; Assessments; Soil Types; Statistical Analysis; Wastewater Disposal; Standards; Wastewater Treatment; Coasts; Australia, Queensland, Gold Coast DO - http://dx.doi.org/10.1007/s00254-004-1026-z ER - TY - JOUR T1 - Sulphur and nitrogen nutrition influence the response of chickpea seeds to an added, transgenic sink for organic sulphur AN - 19806671; 5986236 AB - In order to increase the concentration of the nutritionally essential sulphur amino acids in seed protein, a transgene encoding a methionine- and cysteine-rich protein, sunflower seed albumin (SSA), was transferred to chickpeas (Cicer arietinum L). Transgenic seeds that accumulated SSA contained more methionine and less oxidized sulphur than the controls, suggesting that additional demand for sulphur amino acids from the expression of the transgene stimulated sulphur assimilation. In addition, the activity of trypsin inhibitors, a known family of endogenous, sulphur-rich chickpea seed proteins, was diminished in transgenic, SSA-containing seeds compared with the non- transgenic controls. Together, these results indicate that the reduced sulphur sequestered into SSA was supplied partly by additional sulphur assimilation in the developing transgenic seeds, and partly by some diversion of sulphur amino acids from endogenous seed proteins. Growth of chickpeas on nutrient with a high sulphur-to-nitrogen ratio increased the total seed sulphur content and the accumulation of sulphur amino acids in the seeds, and partly mitigated the effect of SSA accumulation on the trypsin inhibitor amount. The results suggest that free methionine and O-acetylserine (OAS) acted as signals that modulated chickpea seed protein composition in response to the variation in sulphur demand, as well as in response to variation in the nitrogen and sulphur status of the plant. JF - Journal of Experimental Botany AU - Chiaiese, Pasquale AU - Ohkama-Ohtsu, Naoko AU - Molvig, Lisa AU - Godfree, Robert AU - Dove, Hugh AU - Hocart, Charles AU - Fujiwara, Toru AU - Higgins, TJV AU - Tabe, Linda M AD - CSIRO Plant Industry, GPO Box 1600 Canberra ACT 2601, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1889 EP - 1901 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 55 IS - 404 SN - 0022-0957, 0022-0957 KW - Biotechnology and Bioengineering Abstracts KW - Sulfur KW - Cicer arietinum KW - Seeds KW - Amino acids KW - Trypsin KW - Nutrients KW - Nutrition KW - Methionine KW - Albumin KW - Protein composition KW - Helianthus KW - Nitrogen KW - W 30925:Genetic Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19806671?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Botany&rft.atitle=Sulphur+and+nitrogen+nutrition+influence+the+response+of+chickpea+seeds+to+an+added%2C+transgenic+sink+for+organic+sulphur&rft.au=Chiaiese%2C+Pasquale%3BOhkama-Ohtsu%2C+Naoko%3BMolvig%2C+Lisa%3BGodfree%2C+Robert%3BDove%2C+Hugh%3BHocart%2C+Charles%3BFujiwara%2C+Toru%3BHiggins%2C+TJV%3BTabe%2C+Linda+M&rft.aulast=Chiaiese&rft.aufirst=Pasquale&rft.date=2004-08-01&rft.volume=55&rft.issue=404&rft.spage=1889&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Botany&rft.issn=00220957&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Sulfur; Seeds; Amino acids; Trypsin; Albumin; Protein composition; Nutrients; Nutrition; Methionine; Nitrogen; Cicer arietinum; Helianthus ER - TY - JOUR T1 - Transgenic chickpea seeds expressing high levels of a bean alpha -amylase inhibitor AN - 18063518; 6039376 AB - We describe a robust and reproducible Agrobacterium-mediated chickpea transformation method based on kanamycin selection, and its use to introduce the bean alpha AI1 gene into a desi type of chickpea. Bean alpha AI1 was specifically expressed in the seeds, accumulated up to 4.2% of seed protein and was processed to low molecular weight polypeptides as occurs in bean seeds. The transgenic protein was active as an inhibitor of porcine alpha -amylase in vitro. Transgenic chickpeas containing alpha -AI1 strongly inhibited the development of Callosobruchus maculatus and C. chinensis (Col. : Bruchidae) in insect bioassays. JF - Molecular Breeding AU - Sarmah, B K AU - Moore, A AU - Tate, W AU - Molvig, L AU - Morton, R L AU - Rees, D P AU - Chiaiese, P AU - Chrispeels, MJ AU - Tabe, L M AU - Higgins, T AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia; Current address: Department of Agricultural Biotechnology, Assam Agricultural University, Jorhat 785 013, India Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 73 EP - 82 PB - Kluwer Academic Publishers VL - 14 IS - 1 SN - 1380-3743, 1380-3743 KW - Chickpea KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Bioengineering Abstracts; Genetics Abstracts KW - Cicer arietinum KW - ^a-Amylase KW - Plant breeding KW - Transgenic plants KW - Reproductive strategy KW - Callosobruchus chinensis KW - Agrobacterium KW - a-Amylase KW - Callosobruchus maculatus KW - W2 32065:Plants KW - G 07354:Dicotyledons (crops) KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18063518?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+Breeding&rft.atitle=Transgenic+chickpea+seeds+expressing+high+levels+of+a+bean+alpha+-amylase+inhibitor&rft.au=Sarmah%2C+B+K%3BMoore%2C+A%3BTate%2C+W%3BMolvig%2C+L%3BMorton%2C+R+L%3BRees%2C+D+P%3BChiaiese%2C+P%3BChrispeels%2C+MJ%3BTabe%2C+L+M%3BHiggins%2C+T&rft.aulast=Sarmah&rft.aufirst=B&rft.date=2004-08-01&rft.volume=14&rft.issue=1&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Molecular+Breeding&rft.issn=13803743&rft_id=info:doi/10.1023%2FB%3AMOLB.0000037996.01494.12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Agrobacterium; Callosobruchus maculatus; Callosobruchus chinensis; Cicer arietinum; Plant breeding; a-Amylase; Reproductive strategy; Transgenic plants; ^a-Amylase DO - http://dx.doi.org/10.1023/B:MOLB.0000037996.01494.12 ER - TY - JOUR T1 - Effects of spatial resolution on the performance and interpretation of marine ecosystem models AN - 18054423; 5924394 AB - Simplifying models by using coarse spatial resolution can be desirable because it reduces structural, computational and data requirements and can make model interpretation easier. However, spatially simplified models may be incapable of reproducing important dynamics observed in nature. To consider this issue the effect of spatial structure on the output of two trophic ecosystem models (Bay Model 2 (BM2) and the Integrated Generic Bay Ecosystem Model (IGBEM)) was considered using a theoretical approach known as 'deep-shallow model' comparison. This involved comparing simulation runs of 1-, 3-, and 8-box versions of the ecosystem models (the 'shallow' models) with a 59-box version that was used to represent the real world (the 'deep' model). The results indicate that simpler spatial configurations (geometries) can result in less short-term variation, changes in predicted spatial patterns and trophic self- simplification (loss of functional groups), as the opportunity for spatial refuges is reduced. More importantly, models with very little spatial resolution (i.e. 1- and 3-box models) do not capture the effects of changes in nutrient loads or fishing pressure as well as more complex models. The results for the 8- box models used here indicate that some simplification is acceptable, as overall model performance is not overwhelmed by the impacts of trophic self- simplification and a loss of spatial heterogeneity. However, using models with very little spatial resolution (i.e. 1- and 3-box models) can be misleading, as the impacts on system dynamics of the reduced heterogeneity increase. JF - Ecological Modelling AU - Fulton, E A AU - Smith, ADM AU - Johnson, C R AD - CSIRO Division of Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, beth.fulton@csiro.au Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 27 EP - 42 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 176 IS - 1-2 SN - 0304-3800, 0304-3800 KW - Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Spatial structure KW - Biogeochemistry KW - Ecosystems KW - Models KW - Spatial variations KW - Marine KW - Marine environment KW - Ecological distribution KW - Simulation KW - Marine ecology KW - Marine ecosystems KW - Trophic relationships KW - Ecosystem models KW - Modelling KW - Q1 08482:Ecosystems and energetics KW - D 04003:Modeling, mathematics, computer applications KW - O 1090:Instruments/Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18054423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Effects+of+spatial+resolution+on+the+performance+and+interpretation+of+marine+ecosystem+models&rft.au=Fulton%2C+E+A%3BSmith%2C+ADM%3BJohnson%2C+C+R&rft.aulast=Fulton&rft.aufirst=E&rft.date=2004-08-01&rft.volume=176&rft.issue=1-2&rft.spage=27&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.10.026 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Spatial variations; Ecosystems; Marine environment; Ecological distribution; Marine ecology; Simulation; Trophic relationships; Modelling; Marine ecosystems; Ecosystem models; Marine DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.10.026 ER - TY - JOUR T1 - Burr medic (Medicago polymorpha L.) selections for improved N sub(2) fixation with naturalised soil rhizobia AN - 18043898; 5985238 AB - Burr medic (Medicago polymorpha L.) is an annual pasture legume that is widely distributed in southern Australian farming systems. Burr medic is nodulated by rhizobia (Sinorhizobium meliloti and Sinorhizobium medicae) that reside in many Australian soils, but the symbioses that develop are often sub-optimal in their rate of N sub(2) fixation. We attempted to identify burr medic lines, which are able to form effective symbioses with the naturalised Sinorhizobium in Australian field soils, as potential parents for a breeding program. There were three glasshouse experiments. Initially, 222 lines (including the M. polymorpha cvv. Santiago, Serena and Circle Valley) were inoculated with extracts of two soils that had been collected near Waikerie (soil S109) and Lochiel (soil S142) in South Australia. These soils were used because they contained numerically large communities of naturalised Sinorhizobium spp. that produced sub-optimal rates of N sub(2) fixation with cv. Santiago. None of the 222 lines of burr medic were able to form an effective symbiosis with the rhizobia from soil S109. However, when nodulated by the rhizobia from soil S142, some lines (e.g. SA8194) formed a very effective symbiosis, producing up to double the shoot dry matter (DM) of Santiago and eight times the DM of uninoculated plants. Seven promising lines were selected for further testing (with extracts of nine soils). Subsequently, two lines (SA20056 and SA8194) were selected and their symbiotic performance compared with that of Santiago, using extracts from 28 soils. While soil treatment had a major effect on mean shoot DM (soil N103=120 mg, soil N105=17 mg), the three medic lines performed similarly. Santiago, SA20056 and SA8914 all formed ineffective symbioses with the rhizobia in at least half of the 28 soils, even though >95% of the plants were nodulated. These experiments confirm that ineffective symbioses are common between burr medics and the rhizobia that have become naturalised in many Australian soils. Although some lines of burr medic were identified that were able to form more effective symbioses with the rhizobia in individual soils, none were able to form effective symbioses with a wide range of soil rhizobia. If a plant breeding approach is to be used to improve symbiotic performance of burr medic we propose that its hybridisation with other medic species, that have less specific rhizobial needs, will be required. JF - Soil Biology and Biochemistry AU - Charman, N AU - Ballard, R A AD - South Australian Research and Development Institute, GPO Box 397, Adelaide, SA 5001, Australia, charman.nigel@saugov.sa.gov.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1331 EP - 1337 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 36 IS - 8 SN - 0038-0717, 0038-0717 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Soil KW - Symbiosis KW - Nitrogen fixation KW - Breeding KW - Medicago polymorpha KW - Hybridization KW - Sinorhizobium medicae KW - Selection KW - Nitrogen KW - A 01051:Nitrogen cycle UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18043898?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Soil+Biology+and+Biochemistry&rft.atitle=Burr+medic+%28Medicago+polymorpha+L.%29+selections+for+improved+N+sub%282%29+fixation+with+naturalised+soil+rhizobia&rft.au=Charman%2C+N%3BBallard%2C+R+A&rft.aulast=Charman&rft.aufirst=N&rft.date=2004-08-01&rft.volume=36&rft.issue=8&rft.spage=1331&rft.isbn=&rft.btitle=&rft.title=Soil+Biology+and+Biochemistry&rft.issn=00380717&rft_id=info:doi/10.1016%2Fj.soilbio.2004.04.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Medicago polymorpha; Sinorhizobium medicae; Nitrogen; Symbiosis; Breeding; Hybridization; Soil; Nitrogen fixation; Selection DO - http://dx.doi.org/10.1016/j.soilbio.2004.04.014 ER - TY - JOUR T1 - Factors affecting abundance and oviposition rates of a field population of the Old World screw-worm fly, Chrysomya bezziana (Diptera: Calliphoridae) AN - 18034124; 5998226 AB - Sentinel cattle and a grid of swormlure-baited sticky traps were used to monitor a Malaysian population of the Old World screwworm fly, Chrysomya bezziana Villeneuve. Observations were carried out on an isolated cattle station at monthly intervals during the period August 1996 to June 2000. The number of flies caught was unaffected by weather conditions at the time of trapping, but was positively correlated with the total rainfall and the average daily air temperature prevailing 15-28 days earlier, when trapped flies were still juveniles. Trap catches were biased in favor of females, but daily catch rates of both sexes increased significantly the longer traps were open, suggesting that efficacy was related to the differential volatility of the chemicals comprising swormlure. Oviposition on sentinel cattle occurred mostly in late afternoon or early evening but increased significantly as the wound aged. Oviposition rates were positively correlated with female catch rates, but the relationship was curvilinear, suggesting that fly populations may be subject to some form of density-dependent constraint. Consistent differences in oviposition rates on sentinel cattle at different localities on the cattle station suggested the existence of highly clumped, quasi-stationary populations. Differences in trap catches between traps located in pastoral areas and those sited in nearby oil palm or rubber plantations supported this interpretation of the data. These findings are discussed in relation to the use of the sterile insect technique for the control of screwworm fly infestations. JF - Bulletin of Entomological Research AU - Mahon, R J AU - Ahmad, H AU - Wardhaugh, K G AD - CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 359 EP - 368 PB - CAB International VL - 94 IS - 4 SN - 0007-4853, 0007-4853 KW - cattle KW - Diptera KW - Blowflies KW - Animal Behavior Abstracts; Ecology Abstracts; Entomology Abstracts KW - Abundance KW - Climatic conditions KW - Bait KW - Chrysomya bezziana KW - Traps KW - Oviposition KW - Calliphoridae KW - D 04659:Insects KW - Z 05206:Medical & veterinary entomology KW - Y 25423:Insects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18034124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+Entomological+Research&rft.atitle=Factors+affecting+abundance+and+oviposition+rates+of+a+field+population+of+the+Old+World+screw-worm+fly%2C+Chrysomya+bezziana+%28Diptera%3A+Calliphoridae%29&rft.au=Mahon%2C+R+J%3BAhmad%2C+H%3BWardhaugh%2C+K+G&rft.aulast=Mahon&rft.aufirst=R&rft.date=2004-08-01&rft.volume=94&rft.issue=4&rft.spage=359&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+Entomological+Research&rft.issn=00074853&rft_id=info:doi/10.1079%2FBER2004312 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Chrysomya bezziana; Calliphoridae; Abundance; Oviposition; Bait; Traps; Climatic conditions DO - http://dx.doi.org/10.1079/BER2004312 ER - TY - JOUR T1 - Advancing community acceptance of reclaimed water AN - 18027801; 6020669 AB - This paper reports on research into the public acceptance of water reuse, that is, water sourced from highly treated sewage effluent. It distills Bruvold's (1972-1988) USA findings and compares these to an audit of twenty-two recent surveys, with some reference to case studies at eight sites, where potable reuse has been proposed, and four residential reuse sites. It highlights several factors that may help explain a degree of support for potable reuse and confirms relatively high acceptance of non potable reuse. Several areas need further investigation and other known results suggest ways that responsible agencies can promote community trust in the development and management of alternative water resources. JF - Water (Australia) AU - Marks, J S AD - Department of Sociology at The Flinders University of South Australia, GPO Box 2100, Adelaide 2001, Australia, June.Marks@flinders.edu.au Y1 - 2004/08// PY - 2004 DA - August 2004 SP - 46 EP - 51 VL - 31 IS - 5 SN - 0310-0367, 0310-0367 KW - Aqualine Abstracts KW - Water Reuse KW - Reclaimed Water KW - Surveys KW - Water Conservation KW - Water Resources Management KW - Public Opinion KW - AQ 00001:Water Resources and Supplies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18027801?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+%28Australia%29&rft.atitle=Advancing+community+acceptance+of+reclaimed+water&rft.au=Marks%2C+J+S&rft.aulast=Marks&rft.aufirst=J&rft.date=2004-08-01&rft.volume=31&rft.issue=5&rft.spage=46&rft.isbn=&rft.btitle=&rft.title=Water+%28Australia%29&rft.issn=03100367&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Water Reuse; Reclaimed Water; Surveys; Water Conservation; Water Resources Management; Public Opinion ER - TY - JOUR T1 - Biological characterization of Aeromonas spp. isolated from the environment AN - 17886299; 6204030 AB - Cytotoxic enterotoxin (Act) is a key virulence factor in the pathogenesis of infections caused by Aeromonas spp. The cytotoxic enterotoxin gene (act) was detected in 32 out of 69 environmental isolates of Aeromonas spp. by hybridization with the act gene probe. To evaluate the pathogenic potential of the act gene probe-positive isolates, 32 act gene probe-positive and 31 randomly selected act gene probe-negative isolates were tested for enterotoxicity in a suckling mice assay (SMA), for haemolytic activity on sheep blood agar plates, for the presence of CAMP-like factors, and for cytotoxicity in a Vero cell line. The act gene probe-positive isolates significantly differed from the toxin gene probe-negative ones with respect to enterotoxicity in the SMA (P=0 times 009) and haemolytic activity (P=0 times 005). The CAMP-haemolysin phenotype was significantly associated with the rabbit ileal loop assay (P=0 times 08), Vero cell assay (P=0 times 064), and haemolysin production under the microaerophilic conditions (P=0 times 056) of the act gene probe-positive isolates of Aeromonas spp. These data indicated the role of Act in the pathogenesis of Aeromonas infections and that the enterotoxic potential of Aeromonas spp. could be assessed by simply performing a CAMP-haemolysin assay. JF - Epidemiology and Infection AU - Rahim, Z AU - Khan, SI AU - Chopra, A K AD - International Centre for Diarrhoeal Disease Research, Bangladesh: Center for Health and Population Research; GPO Box 128, Dhaka 1000, Bangladesh Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 627 EP - 636 VL - 132 IS - 4 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Blood KW - Agar KW - Cytotoxicity KW - Aeromonas KW - Vero cells KW - virulence factors KW - DNA probes KW - Enterotoxins KW - Infection KW - ACT gene KW - J 02855:Human Bacteriology: Others UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17886299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Biological+characterization+of+Aeromonas+spp.+isolated+from+the+environment&rft.au=Rahim%2C+Z%3BKhan%2C+SI%3BChopra%2C+A+K&rft.aulast=Rahim&rft.aufirst=Z&rft.date=2004-08-01&rft.volume=132&rft.issue=4&rft.spage=627&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268804002298 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Agar; Blood; Cytotoxicity; virulence factors; Vero cells; DNA probes; Enterotoxins; Infection; ACT gene; Aeromonas DO - http://dx.doi.org/10.1017/S0950268804002298 ER - TY - JOUR T1 - An outbreak due to peanuts in their shell caused by Salmonella enterica serotypes Stanley and Newport - sharing molecular information to solve international outbreaks AN - 17880465; 6204024 AB - Salmonellosis is a global problem caused by the international movement of foods and high incidence in exporting countries. In September 2001, in an outbreak investigation Australia isolated Salmonella Stanley from imported peanuts, which resulted in a wider investigation in Canada, England & Wales and Scotland. Patients infected with Salmonella serotypes known to be isolated from peanuts and reported to surveillance systems were interviewed to determine exposure histories. Tagged image file format (TIFF) images of pulsed-field gel electrophoresis (PFGE) patterns of Salmonella isolates were shared electronically amongst laboratories. Laboratories tested packets of `Brand X' peanuts from various lots and product lines. In total, 97 cases of S. Stanley and 12 cases of S. Newport infection were found. Seventy-three per cent (71/97) of S. Stanley cases were in persons of Asian ethnicity. Twenty-eight per cent of cases recalled eating Brand X peanuts and a further 13% had peanuts in their house in the previous month or had eaten Asian-style peanuts. Laboratories isolated S. Stanley, S. Newport, S. Kottbus, S. Lexington and S. Unnamed from Brand X peanuts. Isolates of S. Stanley from peanuts and human patients were indistinguishable by PFGE. This international outbreak resulted from a product originating from one country affecting several others. Rapid sharing of electronic DNA images was a crucial factor in delineating the outbreak; multinational investigations would benefit from a harmonized approach. JF - Epidemiology and Infection AU - Kirk, MD AU - Little, CL AU - Lem, M AU - Fyfe, M AU - Genobile, D AU - Tan, A AU - Threlfall, J AU - Paccagnella, A AU - Lightfoot, D AU - Lyi, H AU - McIntyre, L AU - Ward, L AU - Brown, D J AU - Surnam, S AU - Fisher, IST AD - OzFoodNet, Department of Health and Ageing, Food Safety & Surveillance Section, MDP 15, GPO Box 9848, Canberra City, Australian Capital Territory 2601, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 571 EP - 577 VL - 132 IS - 4 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Houses KW - Serotypes KW - Salmonella enterica KW - Salmonellosis KW - Pulsed-field gel electrophoresis KW - DNA KW - Nuts KW - Shells KW - Infection KW - Food-borne diseases KW - J 02710:Identification, taxonomy and typing KW - J 02846:Gastrointestinal tract UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880465?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=An+outbreak+due+to+peanuts+in+their+shell+caused+by+Salmonella+enterica+serotypes+Stanley+and+Newport+-+sharing+molecular+information+to+solve+international+outbreaks&rft.au=Kirk%2C+MD%3BLittle%2C+CL%3BLem%2C+M%3BFyfe%2C+M%3BGenobile%2C+D%3BTan%2C+A%3BThrelfall%2C+J%3BPaccagnella%2C+A%3BLightfoot%2C+D%3BLyi%2C+H%3BMcIntyre%2C+L%3BWard%2C+L%3BBrown%2C+D+J%3BSurnam%2C+S%3BFisher%2C+IST&rft.aulast=Kirk&rft.aufirst=MD&rft.date=2004-08-01&rft.volume=132&rft.issue=4&rft.spage=571&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026880400216X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Houses; Serotypes; Salmonellosis; DNA; Pulsed-field gel electrophoresis; Nuts; Shells; Infection; Food-borne diseases; Salmonella enterica DO - http://dx.doi.org/10.1017/S095026880400216X ER - TY - JOUR T1 - Gene technology for grain legumes: can it contribute to the food challenge in developing countries? AN - 17880073; 5923728 AB - Grain legumes play a crucial role in the sustainability of agricultural systems and in food protein supply in developing countries. Several constraints that limit crop production or quality have been addressed by conventional breeding and enhanced management, but there are situations where the existing germplasm lacks the required traits. Genetic transformation could help provide solutions to certain constraints, thus improving food security in developing countries. The potential benefits of this form of genetic improvement have not yet been realised, mainly because efficient and reproducible gene transfer systems are not available. We review the state of the art of gene technology for genetic improvement of those grain legumes of major importance to developing countries. Protocols are evaluated for their reproducibility, efficiency and robustness. JF - Plant Science AU - Popelka, J C AU - Terryn, N AU - Higgins, TJV AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, carlos.popelka@csiro.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 195 EP - 206 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 167 IS - 2 SN - 0168-9452, 0168-9452 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - Transformation KW - Food KW - Plant breeding KW - Crop production KW - Gene transfer KW - Reviews KW - Legumes KW - Germplasm KW - Grain KW - Developing countries KW - W2 32065:Plants KW - W2 32440:Plant breeding KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Science&rft.atitle=Gene+technology+for+grain+legumes%3A+can+it+contribute+to+the+food+challenge+in+developing+countries%3F&rft.au=Popelka%2C+J+C%3BTerryn%2C+N%3BHiggins%2C+TJV&rft.aulast=Popelka&rft.aufirst=J&rft.date=2004-08-01&rft.volume=167&rft.issue=2&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Plant+Science&rft.issn=01689452&rft_id=info:doi/10.1016%2Fj.plantsci.2004.03.027 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Developing countries; Legumes; Grain; Food; Crop production; Germplasm; Plant breeding; Reviews; Transformation; Gene transfer DO - http://dx.doi.org/10.1016/j.plantsci.2004.03.027 ER - TY - JOUR T1 - Infant handling and mortality in yellow baboons (Papio cynocephalus): evidence for female reproductive competition? AN - 17715685; 6018567 AB - This study examines negative and positive infant handling behavior in 24 free-ranging yellow baboon infants (Papio cynocephalus) studied over a 5-year period in Mikumi National Park, Tanzania. We test predictions of the female reproductive competition hypothesis to explain patterns of infant handling behavior by adult females (excluding the infant's mother) in relation to observed cases of infant mortality by age 3 months (25% of infants in this study). Results show that: (1) low-ranking infants received more negative infant handling than high-ranking infants; conversely high-ranking infants received more positive infant handling; (2) female kin engaged in higher levels of positive infant handling than did non-kin, whereas non-kin showed higher levels of negative infant handling; (3) rates of negative infant handling varied by season, with high levels at the onset of the rainy season; and (4) high level of negative infant handling was a significant predictor of infant mortality by age 3 months (infant rank and sex did not predict survival). We discuss how the occurrence and interpretation of infant handling behavior in the literature has likely been confused by different definitions of this behavior, as well as differences in the socio-ecological context in which this behavior occurs. JF - Behavioral Ecology and Sociobiology AU - Kleindorfer, S AU - Wasser, S K AD - School of Biological Sciences, Flinders University of South Australia, GPO Box 2100, 5001, Adelaide, Australia, sonia.kleindorfer@flinders.edu.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 328 EP - 337 PB - Springer-Verlag VL - 56 IS - 4 SN - 0340-5443, 0340-5443 KW - Yellow Baboon KW - Animal Behavior Abstracts; Ecology Abstracts KW - Mortality KW - Parent-offspring interactions KW - Reproduction KW - Papio cynocephalus KW - Competition KW - Y 25448:Primates KW - D 04672:Mammals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17715685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Behavioral+Ecology+and+Sociobiology&rft.atitle=Infant+handling+and+mortality+in+yellow+baboons+%28Papio+cynocephalus%29%3A+evidence+for+female+reproductive+competition%3F&rft.au=Kleindorfer%2C+S%3BWasser%2C+S+K&rft.aulast=Kleindorfer&rft.aufirst=S&rft.date=2004-08-01&rft.volume=56&rft.issue=4&rft.spage=328&rft.isbn=&rft.btitle=&rft.title=Behavioral+Ecology+and+Sociobiology&rft.issn=03405443&rft_id=info:doi/10.1007%2Fs00265-004-0798-1 L2 - http://link.springer.de/link/service/journals/00265/bibs/4056004/40560328.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Papio cynocephalus; Mortality; Reproduction; Competition; Parent-offspring interactions DO - http://dx.doi.org/10.1007/s00265-004-0798-1 ER - TY - JOUR T1 - Effect of Oxygen Tension on Adult Articular Chondrocytes in Microcarrier Bioreactor Culture AN - 17710229; 6072196 AB - Tissue-engineering approaches for cartilage repair hold promise for the treatment of cartilage defects. Various methods to prevent or reduce dedifferentiation during chondrocyte expansion are currently under investigation. In the present study we evaluated the effect of oxygen on chondrocyte proliferation, as oxygen has received increased attention as a possible regulator of chondrocyte differentiation and its effect during expansion is uncertain. Therefore, the effect of three oxygen tensions (4, 10.5, and 21%) was investigated in a bioreactor microcarrier culture, which allows precise control of the oxygen tension in the liquid phase. During culture cells acquired a round shape on microcarriers. No differences in proliferation rate of chondrocytes were observed within the range of oxygen tensions evaluated. Cells exhibited predominantly anaerobic metabolism and, per mole of glucose, approximately 2 mol of lactate was produced independent of oxygen tension. Cellular oxygen consumption was comparable for all bioreactor cultures. Nevertheless, specific consumption rates were relatively high (2-4 X 10 super(-17) mol times cell super(-1) times s super(-1)), in comparison with chondrocytes in cartilage (0.8-2.2 X 10 super(-18) mol times cell super(-1)). Subsequent cartilaginous tissue formation in pellets was not affected as qualitatively assessed by safranin-O staining. At the oxygen concentrations evaluated, no effect of oxygen tension was observed on proliferation, oxygen consumption, and yield of lactate on glucose administration. For future investigations of chondrocytes and oxygen, the bioreactor system, which allows precise control and monitoring of oxygen tension, holds promise. JF - Tissue Engineering AU - Malda, J AU - Van Den Brink, P AU - Meeuwse, P AU - Grojec, M AU - Martens, DE AU - Tramper, J AU - Riesle, J AU - Van Blitterswijk, CA AD - Institute of Health and Biomedical Innovation, School of Life Sciences, Queensland University of Technology, GPO Box 2939, Brisbane Qld 4001, Australia, jos@malda.nl Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 987 EP - 994 VL - 10 IS - 7-8 SN - 1076-3279, 1076-3279 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts KW - Oxygen tension KW - Cartilage KW - Glucose KW - Chondrocytes KW - Cell culture KW - Bioreactors KW - safranin-O KW - Oxygen consumption KW - Tissue engineering KW - Oxygen KW - Lactic acid KW - Chondrogenesis KW - W 30965:Miscellaneous, Reviews KW - W3 33220:Cell culture KW - W4 110:Biomedical Materials & Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17710229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tissue+Engineering&rft.atitle=Effect+of+Oxygen+Tension+on+Adult+Articular+Chondrocytes+in+Microcarrier+Bioreactor+Culture&rft.au=Malda%2C+J%3BVan+Den+Brink%2C+P%3BMeeuwse%2C+P%3BGrojec%2C+M%3BMartens%2C+DE%3BTramper%2C+J%3BRiesle%2C+J%3BVan+Blitterswijk%2C+CA&rft.aulast=Malda&rft.aufirst=J&rft.date=2004-08-01&rft.volume=10&rft.issue=7-8&rft.spage=987&rft.isbn=&rft.btitle=&rft.title=Tissue+Engineering&rft.issn=10763279&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Oxygen tension; Chondrocytes; Oxygen; Bioreactors; Cell culture; Cartilage; Glucose; Oxygen consumption; Lactic acid; Tissue engineering; Chondrogenesis; safranin-O ER - TY - JOUR T1 - Ultra-high-resolution seasonality of trace-ion species and oxygen isotope ratios in Antarctic firn over four annual cycles AN - 17391753; 6491288 AB - Ultra-high-resolution firn-core records covering four annual cycles of oxygen isotope ratios ( delta super(18)O) and trace-ion species were generated from a high-accumulation site on Law Dome, East Antarctica. Event-scale dating of the records was established using hourly snow accumulation measurements from a co-located automatic weather station (AWS). These net accumulation events were used to examine the seasonal timing of delta super(18)O and a suite of trace-ion species including marine biogenic sulphur compounds (methanesulphonic acid (MSA), non-sea salt sulphate), nitrate and major sea-salt species (sodium, chloride, magnesium). The ultra-high-resolution nature of this study and independent dating scale provide an opportunity to examine exact timings in the seasonality of each species. The traditional summer-maximum species of delta super(18)O and MSA show consistent relative phasing during mid-summer over the four annual cycles. Nitrate shows an erratic seasonal cycle with a general trend characterized by narrow peaks during spring and early summer, preceding the mid-summer peaks in delta super(18)O and MSA. Non-sea-salt sulphate cycles indicate similar characteristics to MSA signals during summer, but are more comparable to nitrate signals during spring, autumn and winter. This suggests the summer non-sea-salt sulphate signal is driven by biological activity, although this species appears to be linked with nitrate signals outside the summer season. Finally, the sea-salt species indicate a seasonal cycle characterized by maximum concentrations during spring, winter and autumn. Event-scale dating of the firn-core records allows direct comparisons between the seasonal cycles and meteorological conditions. Contemporaneous local air-temperature measurements are compared with the high-resolution delta super(18)O record. This allows a detailed investigation of the relationship between site temperature and delta super(18)O signals in the ice core. JF - Annals of Glaciology AU - McMorrow, A AU - van Ommen, TD AU - Morgan, V AU - Curran AD - Technology Futures Team, Australian Greenhouse Office, Department of the Environment and Heritage, John Gorton Building, GPO Box 787, Canberra, ACT 2601, Australia, Alison.McMorrow@deh.gov.au A2 - Jacka, TH (ed) Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 34 EP - 40 PB - International Glaciological Society, Lensfield Road Cambridge CB2 1ER UK VL - 39 SN - 0260-3055, 0260-3055 KW - Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts KW - Sulfates KW - Timing KW - Nitrates KW - Temperature KW - Snow accumulation KW - Antarctic conferences KW - Antarctic glaciology KW - Oxygen isotopes KW - Glacier symposia KW - Sulfur compounds in seawater KW - Dating KW - Antarctica, Wilkes Land, Budd Coast, Law Dome KW - Oxygen Isotopes KW - Seasonal variability KW - Accumulation KW - Automatic weather stations KW - Meteorological conditions KW - Firn KW - SW 0880:Chemical processes KW - M2 551.321:General Methods/Instruments (551.321) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17391753?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Annals+of+Glaciology&rft.atitle=Ultra-high-resolution+seasonality+of+trace-ion+species+and+oxygen+isotope+ratios+in+Antarctic+firn+over+four+annual+cycles&rft.au=McMorrow%2C+A%3Bvan+Ommen%2C+TD%3BMorgan%2C+V%3BCurran&rft.aulast=McMorrow&rft.aufirst=A&rft.date=2004-08-01&rft.volume=39&rft.issue=&rft.spage=34&rft.isbn=&rft.btitle=&rft.title=Annals+of+Glaciology&rft.issn=02603055&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-06-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Oxygen isotopes; Sulfur compounds in seawater; Glacier symposia; Snow accumulation; Seasonal variability; Meteorological conditions; Antarctic conferences; Automatic weather stations; Antarctic glaciology; Timing; Sulfates; Nitrates; Dating; Temperature; Oxygen Isotopes; Accumulation; Firn; Antarctica, Wilkes Land, Budd Coast, Law Dome ER - TY - JOUR T1 - Pediatric mortality in Africa: Plasmodium falciparum malaria as a cause or risk? AN - 17306398; 6068599 AB - The disability adjusted life year (DALY) approach of defining cause-specific health burdens is becoming the benchmark for international disease control prioritization. For malaria, this categorical approach may not fully capture its burden that includes chronic anemia, low birth weight, and enhancement of the severity of other childhood diseases. We investigated the extent to which malaria acts as a risk factor for all-cause mortality in African children less than five years of age from 1) ecologic associations between Plasmodium falciparum infection prevalence (PR) and under-five mortality, and 2) reductions in all-cause under-five mortality achieved in malaria intervention trials. Across 48 demographic surveillance studies, when adjusted for secular trends, PR more than doubled all-cause mortality (P = 0.0001). Trials of insecticide-treated mosquito nets generally found smaller population-attributable fractions of pediatric mortality to malaria infection, which may relate to their imperfect coverage and efficacy. In conclusion, the disability and death burden due to malaria in African children could be higher than that detectable from cause-specific DALY estimations. JF - American Journal of Tropical Medicine and Hygiene AU - Snow, R W AU - Korenromp, EL AU - Gouws, E AD - Kenya Medical Research Institute-Wellcome Trust Collaborative Program, 00100 GPO, PO Box 43640, Nairobi, Kenya, rsnow@wtnairobi.mimcom.net Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 16 EP - 24 VL - 71 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Risk Abstracts KW - K 03090:Protozoa: human KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17306398?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Pediatric+mortality+in+Africa%3A+Plasmodium+falciparum+malaria+as+a+cause+or+risk%3F&rft.au=Snow%2C+R+W%3BKorenromp%2C+EL%3BGouws%2C+E&rft.aulast=Snow&rft.aufirst=R&rft.date=2004-08-01&rft.volume=71&rft.issue=2&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-10-01 N1 - SuppNotes - Special Issue: Malaria in Africa. N1 - Last updated - 2011-12-13 ER - TY - CONF T1 - Invaders in the north -- an appraisal of Queensland's (Australia) strategic approach to pest fish management AN - 17298989; 6111223 AB - Invasive fish species have long been considered a problem in Queensland, Australia with 17 species forming self-sustaining populations in Queensland waters. The Queensland Fisheries Service (QFS) established a project in 1999 to develop a strategy for controlling these fish. "Controlling exotic pest fishes--an operational strategy for Queensland Freshwaters 2000-2005" (the strategy) was released in early 2001 and has been progressively implemented since that time. QFS have worked very closely with the community and industry in the management of invasive species and the pest fish project has had some notable successes. These include a well-recognised state-wide education programme and the installation of multi-million dollar screens on impoundments to prevent inter-basin transfer. In recognition of the increasing rate of fish smuggling into Queensland, a process has been developed to amend the current legislation to ensure that it is enforceable, accepted by the community and industry, and scientifically valid. This workshop will explore the reasons for these successes and some of the challenges encountered whilst implementing the strategy. The future policy direction of the pest fish programme will also be discussed as QFS intends to manage pest fish within a wider habitat management framework. This holistic approach to habitat management will incorporate many of the approaches to community engagement and education developed during the pest fish project. JF - S I R Publishing, P.O. Box 399 Wellington New Zealand. p. 566. Aug 2004. AU - Mackenzie, R Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 566 PB - S I R Publishing, P.O. Box 399 Wellington New Zealand, [URL:http://www.rsnz.govt.nz/] VL - 38 IS - 3 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Freshwater KW - Q5 01521:Mechanical and natural changes KW - Q1 01485:Species interactions: pests and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17298989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=Invaders+in+the+north+--+an+appraisal+of+Queensland%27s+%28Australia%29+strategic+approach+to+pest+fish+management&rft.au=Mackenzie%2C+R&rft.aulast=Mackenzie&rft.aufirst=R&rft.date=2004-08-01&rft.volume=38&rft.issue=3&rft.spage=566&rft.isbn=&rft.btitle=&rft.title=&rft.issn=00288330&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - SuppNotes - Special Issue: invasive species N1 - Last updated - 2011-12-13 ER - TY - CONF T1 - Eradication of exotic pest fish -- present and future options AN - 17298945; 6111216 AB - A wide range of techniques have been proposed to manage, if not actually eradicate invasive fish species. A number have been tried (e.g., physical removal, biocides), usually with limited success, others are currently being attempted (e.g., sterile male releases), and still more are under development (e.g., genetic technologies). These techniques and attempts will be reviewed briefly, the strengths and weaknesses of each will be discussed, and their potential for pest eradication evaluated in a general framework that looks at both the likelihood they will achieve eradication, or at least substantial and sustained reduction of pest impacts, and the likelihood the public will ever let them be used. JF - S I R Publishing, P.O. Box 399 Wellington New Zealand. p. 564. Aug 2004. AU - Thresher, R Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 564 PB - S I R Publishing, P.O. Box 399 Wellington New Zealand, [URL:http://www.rsnz.govt.nz/] VL - 38 IS - 3 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Marine KW - Q5 01522:Protective measures and control KW - O 4090:Conservation and Environmental Protection KW - Q1 01485:Species interactions: pests and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17298945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=Eradication+of+exotic+pest+fish+--+present+and+future+options&rft.au=Thresher%2C+R&rft.aulast=Thresher&rft.aufirst=R&rft.date=2004-08-01&rft.volume=38&rft.issue=3&rft.spage=564&rft.isbn=&rft.btitle=&rft.title=&rft.issn=00288330&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - SuppNotes - Special Issue: invasive species N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Wastewater treatment effectiveness: A review AN - 16179332; 6020675 AB - A review of the literature was undertaken to determine the ranges of pathogen removal by the unit processes commonly used in the treatment of wastewater prior to disinfection. It was found that the order of effectiveness ranged from primary sedimentation, followed by trickling filter, physicochemical treatment with alum/polymer, rapid sand filtration, activated sludge, physicochemical treatment with lime, dissolved air flotation, slow sand filtration, lagoons (with sufficient HRT) and membrane processes. JF - Water (Australia) AU - Parkinson, A AU - Roddick, F A AD - School of Civil and Chemical Engineering, RMIT University, GPO Box 2476V, Melbourne, Victoria, 3001, Australia Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 63 EP - 68 VL - 31 IS - 5 SN - 0310-0367, 0310-0367 KW - Aqualine Abstracts KW - Disinfection KW - Performance Evaluation KW - Membranes KW - Physicochemical Treatment KW - Sand Filters KW - Trickling Filters KW - Literature Review KW - Sedimentation KW - Wastewater Treatment KW - Flotation KW - Lagoons KW - AQ 00006:Sewage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16179332?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+%28Australia%29&rft.atitle=Wastewater+treatment+effectiveness%3A+A+review&rft.au=Parkinson%2C+A%3BRoddick%2C+F+A&rft.aulast=Parkinson&rft.aufirst=A&rft.date=2004-08-01&rft.volume=31&rft.issue=5&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=Water+%28Australia%29&rft.issn=03100367&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2004-10-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Disinfection; Performance Evaluation; Membranes; Physicochemical Treatment; Sand Filters; Trickling Filters; Sedimentation; Literature Review; Lagoons; Flotation; Wastewater Treatment ER - TY - JOUR T1 - Drinking Water Contaminants, Gene Polymorphisms, and Fetal Growth AN - 14709139; 10667558 JF - Environmental Health Perspectives AU - Infante-Rivard, Claire Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1213 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHLOROFORM KW - QUEBEC PROVINCE KW - TRIHALOMETHANE KW - RISK ASSESSMENT KW - REPRODUCTION, HUMAN KW - WATER, DRINKING KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709139?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Drinking+Water+Contaminants%2C+Gene+Polymorphisms%2C+and+Fetal+Growth&rft.au=Infante-Rivard%2C+Claire&rft.aulast=Infante-Rivard&rft.aufirst=Claire&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1213&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; CHLOROFORM; REPRODUCTION, HUMAN; QUEBEC PROVINCE; WATER, DRINKING; GENETICS, HUMAN; TRIHALOMETHANE ER - TY - JOUR T1 - Pesticide Spraying for West Nile Virus Control and Emergency Department Asthma Visits in New York City, 2000 AN - 14708012; 10667552 AB - During the 2000 West Nile Virus season, New York City used a pyrethroid pesticide exclusively. A time-series analysis across ZIP codes in the city was conducted to determine whether truck-based ground spraying precipitated an increase in asthma exacerbations requiring emergency department treatment. Only data from the 11 public hospital emergency departments were used. Results showed that the pesticide application schedule coincided with both the summer trough and the subsequent autumn increase in asthma visits. Multivariate analysis revealed no significant association between neighborhood spraying and subsequent rates of emergency department visits for asthma. JF - Environmental Health Perspectives AU - Karpati, Adam M AU - Perrin, Mary C AU - Matte, Tom AU - Leighton, Jessica AU - Schwartz, Joel AU - Barr, RGraham Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1183 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PYRETHROID PESTICIDES KW - HEALTH FACILITIES KW - INSECTICIDE APPLICATION KW - ASTHMA KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pesticide+Spraying+for+West+Nile+Virus+Control+and+Emergency+Department+Asthma+Visits+in+New+York+City%2C+2000&rft.au=Karpati%2C+Adam+M%3BPerrin%2C+Mary+C%3BMatte%2C+Tom%3BLeighton%2C+Jessica%3BSchwartz%2C+Joel%3BBarr%2C+RGraham&rft.aulast=Karpati&rft.aufirst=Adam&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1183&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH FACILITIES; PYRETHROID PESTICIDES; INSECTICIDE APPLICATION; ASTHMA; NEW YORK CITY ER - TY - JOUR T1 - Behavioral Alterations in Response to Fear-Provoking Stimuli and Tranylcypromine Induced by Perinatal Exposure to Bisphenol A and Nonylphenol in Male Rats AN - 14707983; 10667548 AB - The adverse effects of a low-dose perinatal bisphenol A or nonylphenol exposure on the behavioral characteristics of male rats were investigated. The tests included an open-field test, spontaneous activity during a dark phase, a step-through passive avoidance test, an elevated plus-maze test, and a two-way shuttle-box avoidance test. In addition, behavioral responses to tranylcypromine (Tcy), a monoamine oxidase inhibitor, were also considered. Dams were dosed orally with bisphenol A at a dose of 0.1 mg/kg/d or with nitrophenol at doses of 0.1 or 10.0 mg/kg/d from gestational day 3 until postnatal day 20. One male pup per litter was selected randomly for behavioral testing. Results showed that behavioral alterations by perinatal exposure to the compounds were observed only in specific challenges involving fear-provoking stimuli and pharmacologic disruption of the monoaminergic system. In the passive avoidance test, offspring perinatally exposed to bisphenol A or nitrophenol appeared to be more sensitive to fear-inducing shock than were control offspring, and in the active avoidance test, bisphenol A and low-dose nonylphenol showed clear or partial adverse effects on behavior, respectively. In the monoamine-disruption test, Tcy-induced increases in locomotion were significantly less marked in the bisphenol A-treated and low-dose nonylphenol-treated offspring, but not in the high-dose nonylphenol-treated offspring, compared to controls. JF - Environmental Health Perspectives AU - Negishi, Takayuki AU - Kawasaki, Katsuyoshi AU - Suzaki, Shingo AU - Maeda, Haruna AU - Ishii, Yoshiyuki AU - Kyuwa, Shigeru AU - Kuroda, Yoichiro Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1159 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BEHAVIOR KW - PHYSIOLOGICAL EFFECTS KW - REPRODUCTION, ANIMAL KW - RATS KW - HORMONES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Behavioral+Alterations+in+Response+to+Fear-Provoking+Stimuli+and+Tranylcypromine+Induced+by+Perinatal+Exposure+to+Bisphenol+A+and+Nonylphenol+in+Male+Rats&rft.au=Negishi%2C+Takayuki%3BKawasaki%2C+Katsuyoshi%3BSuzaki%2C+Shingo%3BMaeda%2C+Haruna%3BIshii%2C+Yoshiyuki%3BKyuwa%2C+Shigeru%3BKuroda%2C+Yoichiro&rft.aulast=Negishi&rft.aufirst=Takayuki&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1159&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 11 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PHYSIOLOGICAL EFFECTS; BEHAVIOR; REPRODUCTION, ANIMAL; RATS; HORMONES ER - TY - JOUR T1 - Perfluorooctane Sulfonate (PFOS) and Related Perfluorinated Compounds in Human Maternal and Cord Blood Samples: Assessment of PFOS Exposure in a Susceptible Population During Pregnancy AN - 14707910; 10667556 AB - Cord blood and maternal serum samples were collected from a group of pregnant women recruited at Sapporo Toho Hospitals in Hokkaido, Japan, and the samples were analyzed for concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorooctane sulfonylamide (PFOSA), which are stable chemicals with a wide range of industrial and consumer applications. The analytical procedures used are described. In the 15 blood pairs analyzed, PFOS concentrations in maternal serum samples ranged 4.917.6 ng/ml, while those in cord blood ranged 1.65.3 ng/ml, and the levels in the two matrices were correlated highly. Only a small number of maternal samples had detectable PFOA, whereas no cord blood samples did, which was also found for PFOSA. JF - Environmental Health Perspectives AU - Inoue, Koichi AU - Okada, Fumio AU - Ito, Rie AU - Kato, Shizue AU - Sasaki, Seiko AU - Nakajima, Sonomi AU - Uno, Akiko Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1204 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - ORGANIC COMPOUNDS KW - REPRODUCTION, HUMAN KW - JAPAN KW - FLUORINE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707910?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Perfluorooctane+Sulfonate+%28PFOS%29+and+Related+Perfluorinated+Compounds+in+Human+Maternal+and+Cord+Blood+Samples%3A+Assessment+of+PFOS+Exposure+in+a+Susceptible+Population+During+Pregnancy&rft.au=Inoue%2C+Koichi%3BOkada%2C+Fumio%3BIto%2C+Rie%3BKato%2C+Shizue%3BSasaki%2C+Seiko%3BNakajima%2C+Sonomi%3BUno%2C+Akiko&rft.aulast=Inoue&rft.aufirst=Koichi&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1204&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; ORGANIC COMPOUNDS; JAPAN; REPRODUCTION, HUMAN; FLUORINE ER - TY - JOUR T1 - Discriminating Different Classes of Toxicants by Transcript Profiling AN - 14707831; 10667800 AB - Results from animal studies involving 28 well-known hepatotoxicants and three nonhepatotoxic compounds were used to discriminate different classes of toxicants by transcript profiling. Recursive feature elimination was used to create sets of informative genes, and all support vector machine classifications were based on the software package, LIBSVM. Results revealed that classification problems in toxicogenomics could be addressed effectively by the supervised learning approach. By combining support vector machine parameter optimization with a compound-based external cross-validation scheme and recursive feature elimination, accurate classification of the compounds included in the training set was achieved. JF - Environmental Health Perspectives AU - Steiner, Guido AU - Suter, Laura AU - Boess, Franziska AU - Gasser, Rodolfo AU - de Vera, Maria Cristina AU - Albertini, Silvio AU - Ruepp, Stefan Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1236 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707831?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Discriminating+Different+Classes+of+Toxicants+by+Transcript+Profiling&rft.au=Steiner%2C+Guido%3BSuter%2C+Laura%3BBoess%2C+Franziska%3BGasser%2C+Rodolfo%3Bde+Vera%2C+Maria+Cristina%3BAlbertini%2C+Silvio%3BRuepp%2C+Stefan&rft.aulast=Steiner&rft.aufirst=Guido&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1236&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; HEPATOTOXICITY ER - TY - JOUR T1 - Fetal Exposure to PCBs and Their Hydroxylated Metabolites in a Dutch Cohort AN - 14707815; 10667557 AB - Levels of PCBs and hydroxylated PCBs (OH-PCBs) were measured in mothers and children at birth in a cohort recruited in the Netherlands. In total, 51 paired maternal and cord blood plasma samples were analyzed. The sum PCBs in maternal plasma ranged 113619 ng/g lipid, and those in cord blood ranged 78809 ng/g lipid, while the respective sum OH-PCBs ranged 14125 and 49244 ng/g lipid. With the exception of PCB congeners 118 and 156, there was a significant correlation between the maternal and cord plasma levels, indicating transfer across the placental barrier. JF - Environmental Health Perspectives AU - Soechitram, Shalini Devi AU - Athanasiadou, Maria AU - Hovander, Lotta AU - Bergman, Ake AU - Sauer, Pieter Jan Jacob Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1208 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - POLYCHLORINATED BIPHENYLS KW - METABOLIC ACTIVATION KW - REPRODUCTION, HUMAN KW - NETHERLANDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707815?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Fetal+Exposure+to+PCBs+and+Their+Hydroxylated+Metabolites+in+a+Dutch+Cohort&rft.au=Soechitram%2C+Shalini+Devi%3BAthanasiadou%2C+Maria%3BHovander%2C+Lotta%3BBergman%2C+Ake%3BSauer%2C+Pieter+Jan+Jacob&rft.aulast=Soechitram&rft.aufirst=Shalini&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1208&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; METABOLIC ACTIVATION; NETHERLANDS; REPRODUCTION, HUMAN ER - TY - JOUR T1 - Hair Mercury Levels in U.S. Children and Women of Childbearing Age: Reference Range Data from NHANES 19992000 AN - 14707785; 10667549 AB - The National Health and Nutrition Examination Survey (NHANES) mercury assessment component targeted children 15 yr of age and women 1649 yr of age, and the assessment conducted in 19992000 included a dietary interview and blood, hair, and urinary Hg assessments. Survey results are presented for hair Hg levels in relation to race/ethnicity, fish consumption frequency level, pregnancy status, and education level. Among children, the geometric mean total hair Hg concentration was 0.12 mu g/g, and non-Hispanic black and Mexican-American children had higher levels than non-Hispanic white children, and boys and higher levels than girls. Hair Hg levels increased with increasing frequency of fish consumption for both children and adults. Hair Hg levels of pregnant women did not differ from those of nonpregnant women. Weighted Pearson correlations between log blood and log hair Hg were 0.67 and 0.79 for children and women, respectively. JF - Environmental Health Perspectives AU - McDowell, Margaret A AU - Dillon, Charles F AU - Osterloh, John AU - Bolger, PMichael AU - Pellizzari, Edo AU - Fernando, Reshan AU - Montes de Oca, Ruben Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1165 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PREGNANCY KW - DIET KW - AGE COMPARISONS KW - HAIR KW - BLOOD ANALYSIS KW - NATIONALITY COMPARISONS KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Hair+Mercury+Levels+in+U.S.+Children+and+Women+of+Childbearing+Age%3A+Reference+Range+Data+from+NHANES+1999%26lt%3BND%26gt%3B2000&rft.au=McDowell%2C+Margaret+A%3BDillon%2C+Charles+F%3BOsterloh%2C+John%3BBolger%2C+PMichael%3BPellizzari%2C+Edo%3BFernando%2C+Reshan%3BMontes+de+Oca%2C+Ruben&rft.aulast=McDowell&rft.aufirst=Margaret&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1165&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; PREGNANCY; DIET; NATIONALITY COMPARISONS; AGE COMPARISONS; MERCURY; HAIR ER - TY - JOUR T1 - The Need to Decide If All Estrogens Are Intrinsically Similar AN - 14707737; 10667544 AB - Genes expressed in the immature mouse uterus when grown in response to treatment with phytoestrogens and synthetic estrogens were compared. The estrogens included 17 beta -estradiol, diethylstilbestrol, and genistein, which constituted a physiologic estrogen, a synthetic estrogen, and a phytoestrogen, respectively. A high degree of similarity was found between the transcriptional responses to each of the three estrogens. While the estrogens were found to alter the expression of some genes with different magnitudes, the data showed that the same genes were affected during equivalent uterotrophic responses. JF - Environmental Health Perspectives AU - Moggs, Jonathan G AU - Ashby, John AU - Tinwell, Helen AU - Lim, Fei Ling AU - Moore, David J AU - Kimber, Ian AU - Orphanides, George Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1137 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PLANTS, BIOLOGIC KW - DIETHYLSTILBESTROL KW - BIOASSAY KW - HORMONES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Need+to+Decide+If+All+Estrogens+Are+Intrinsically+Similar&rft.au=Moggs%2C+Jonathan+G%3BAshby%2C+John%3BTinwell%2C+Helen%3BLim%2C+Fei+Ling%3BMoore%2C+David+J%3BKimber%2C+Ian%3BOrphanides%2C+George&rft.aulast=Moggs&rft.aufirst=Jonathan&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1137&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - PLANTS, BIOLOGIC; DIETHYLSTILBESTROL; BIOASSAY; HORMONES ER - TY - JOUR T1 - Valproic Acid Teratogenicity: a Toxicogenomics Approach AN - 14707334; 10667799 AB - Spotted cDNA microarrays were used to monitor global gene expression changes in response to the anti-epileptic drug, valproic acid, which has been shown to induce neural tube defects in human, mouse, and other vertebrate embryos. Altered expressions of multiple genes in mouse embryos after treatment with valproic acid are reported and discussed in light of neural tube development and previously known valproic acid actions. Using the mouse embryo-carcinoma cell line, P19, as an in vitro model of early pluripotent embryonic cells, a subset of valproic acid-responsive genes is identified that may be particularly relevant potential biomarkers of valproic acid teratogenicity. JF - Environmental Health Perspectives AU - Kultima, Kim AU - Nystrom, Anna-Maja AU - Scholz, Birger AU - Gustafson, Anne-Lee AU - Dencker, Lennart AU - Stigson, Michael Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1225 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GENETICS, ANIMAL KW - TERATOGENIC AGENTS KW - DRUGS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Valproic+Acid+Teratogenicity%3A+a+Toxicogenomics+Approach&rft.au=Kultima%2C+Kim%3BNystrom%2C+Anna-Maja%3BScholz%2C+Birger%3BGustafson%2C+Anne-Lee%3BDencker%2C+Lennart%3BStigson%2C+Michael&rft.aulast=Kultima&rft.aufirst=Kim&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1225&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; TERATOGENIC AGENTS; DRUGS ER - TY - JOUR T1 - The Relationship Between Levels of PCBs and Pesticides in Human Hair and Blood: Preliminary Results AN - 14706927; 10667554 AB - Blood and hair samples were collected from ten Caucasian subjects, and the relationship between PCB and pesticide levels in the two matrices was explored. The hair samples were also washed, and the washing solution was analyzed. The analytical protocol employed is described. Strong correlations were found between hair and blood levels of p,p'-DDE, and the correlation was stronger than that for p,p'-DDT. A moderate hair-to-blood correlation was found for PCB congeners 28, 74, 99, 170, 180, and 194. The percentage of lipids and the levels of organic contaminants in hair were generally higher than those in serum, with levels in hair above the detection limits for all compounds except PCB congener 25 and dieldrin. Washing the hair with shampoo, as opposed to water only, decreased the levels of PCBs, pesticides, and lipids by 2533%, on average, but for less-chlorinated congeners, the decrease was larger. JF - Environmental Health Perspectives AU - Altshul, Larisa AU - Covaci, Adrian AU - Hauser, Russ Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1193 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PESTICIDE RESIDUES KW - BIOLOGICAL INDICATORS KW - BIOACCUMULATION, HUMAN KW - HAIR KW - BLOOD ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Relationship+Between+Levels+of+PCBs+and+Pesticides+in+Human+Hair+and+Blood%3A+Preliminary+Results&rft.au=Altshul%2C+Larisa%3BCovaci%2C+Adrian%3BHauser%2C+Russ&rft.aulast=Altshul&rft.aufirst=Larisa&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1193&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; PESTICIDE RESIDUES; BIOLOGICAL INDICATORS; BIOACCUMULATION, HUMAN; HAIR ER - TY - JOUR T1 - The Association Between Environmental Lead Exposure and Bone Density in Children AN - 14706754; 10667555 JF - Environmental Health Perspectives AU - Campbell, James R AU - Rosier, Randy N AU - Novotny, Leonore AU - Puzas, JEdward Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1200 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - BONE GROWTH KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Association+Between+Environmental+Lead+Exposure+and+Bone+Density+in+Children&rft.au=Campbell%2C+James+R%3BRosier%2C+Randy+N%3BNovotny%2C+Leonore%3BPuzas%2C+JEdward&rft.aulast=Campbell&rft.aufirst=James&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1200&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD LEAD LEVEL; BONE GROWTH; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Gene Interaction Network Suggests Dioxin Induces a Significant Linkage Between Aryl Hydrocarbon Receptor and Retinoic Acid Receptor Beta AN - 14706079; 10667798 JF - Environmental Health Perspectives AU - Toyoshiba, Hiroyoshi AU - Yamanaka, Takeharu AU - Sone, Hideko AU - Parham, Frederick M AU - Walker, Nigel J AU - Martinez, Jeanelle AU - Portier, Christopher J Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1217 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MATHEMATIC MODELS, BIOLOGICAL KW - GENETICS, HUMAN KW - TETRACHLORODIBENZODIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Gene+Interaction+Network+Suggests+Dioxin+Induces+a+Significant+Linkage+Between+Aryl+Hydrocarbon+Receptor+and+Retinoic+Acid+Receptor+Beta&rft.au=Toyoshiba%2C+Hiroyoshi%3BYamanaka%2C+Takeharu%3BSone%2C+Hideko%3BParham%2C+Frederick+M%3BWalker%2C+Nigel+J%3BMartinez%2C+Jeanelle%3BPortier%2C+Christopher+J&rft.aulast=Toyoshiba&rft.aufirst=Hiroyoshi&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1217&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MATHEMATIC MODELS, BIOLOGICAL; GENETICS, HUMAN; TETRACHLORODIBENZODIOXINS ER - TY - JOUR T1 - Lead, Diabetes, Hypertension, and Renal Function: the Normative Aging Study AN - 14705376; 10667551 AB - Data from subjects included in the Normative Aging Study with no previous known heavy lead exposure were used to examine the effect of low-level bone and blood Pb levels on renal function. The relationships were assessed further by considering the potential modifying effect of diabetes and hypertension. Significant associations of bone Pb with prospective follow-up measures and annual change in serum creatinine were observed among subject with diabetes. The analysis of Pb, hypertension, and serum creatinine indicated that both the association between follow-up blood Pb with follow-up measures of serum creatinine and the association between tibia Pb and prospective annual change in serum creatinine were modified significantly by hypertensive status, with hypertensive subjects having stronger and more significant associations. JF - Environmental Health Perspectives AU - Tsaih, Shirng-Wern AU - Korrick, Susan AU - Schwartz, Joel AU - Amarasiriwardena, Chitra AU - Aro, Antonio AU - Sparrow, David AU - Hu, Howard Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1178 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - NEPHROTOXICITY KW - CARDIOVASCULAR DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705376?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lead%2C+Diabetes%2C+Hypertension%2C+and+Renal+Function%3A+the+Normative+Aging+Study&rft.au=Tsaih%2C+Shirng-Wern%3BKorrick%2C+Susan%3BSchwartz%2C+Joel%3BAmarasiriwardena%2C+Chitra%3BAro%2C+Antonio%3BSparrow%2C+David%3BHu%2C+Howard&rft.aulast=Tsaih&rft.aufirst=Shirng-Wern&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1178&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD LEAD LEVEL; CARDIOVASCULAR DISORDERS; NEPHROTOXICITY ER - TY - JOUR T1 - Using Human Disease Outbreaks as a Guide to Multilevel Ecosystem Interventions AN - 14705356; 10667545 AB - It has been suggested that disease incidence within a human population can be used as a bioindicator of ecosystem health. The incidence data most useful in this regard relate to vector-mediated diseases and infections that appear to transcend simple transmission categories. Examples are provided that show that many stresses and disruptions to natural ecosystem functioning can be identified only as a result of detailed epidemiologic investigations. By identifying the ecosystem disruption affecting human health using an outbreak-based approach, appropriate strategies for intervention and remediation can be introduced. Such examples are provided for ecosystem interventions for local, regional, and global outbreaks. JF - Environmental Health Perspectives AU - Cook, Angus AU - Jardine, Andrew AU - Weinstein, Philip Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1143 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - EPIDEMICS KW - BIOLOGICAL INDICATORS KW - ECOLOGY, HUMAN KW - ECOSYSTEM DYNAMICS KW - ECOLOGICAL IMBALANCE KW - DISEASES AND DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14705356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+Human+Disease+Outbreaks+as+a+Guide+to+Multilevel+Ecosystem+Interventions&rft.au=Cook%2C+Angus%3BJardine%2C+Andrew%3BWeinstein%2C+Philip&rft.aulast=Cook&rft.aufirst=Angus&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1143&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 58 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - EPIDEMICS; ECOSYSTEM DYNAMICS; ECOLOGICAL IMBALANCE; BIOLOGICAL INDICATORS; DISEASES AND DISORDERS; ECOLOGY, HUMAN ER - TY - JOUR T1 - Assessment of Prediction Confidence and Domain Extrapolation of Two StructureActivity Relationship Models for Predicting Estrogen Receptor Binding Activity AN - 14704253; 10667801 JF - Environmental Health Perspectives AU - Tong, Weida AU - Xie, Qian AU - Hong, Huixiao AU - Shi, Leming AU - Fang, Hong AU - Perkins, Roger Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1249 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHEMICAL ANALYSIS KW - HORMONAL EFFECTS KW - QUANTITATIVE STRUCTURE-ACTIVITY RELATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Assessment+of+Prediction+Confidence+and+Domain+Extrapolation+of+Two+Structure%26lt%3BND%26gt%3BActivity+Relationship+Models+for+Predicting+Estrogen+Receptor+Binding+Activity&rft.au=Tong%2C+Weida%3BXie%2C+Qian%3BHong%2C+Huixiao%3BShi%2C+Leming%3BFang%2C+Hong%3BPerkins%2C+Roger&rft.aulast=Tong&rft.aufirst=Weida&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1249&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL ANALYSIS; HORMONAL EFFECTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATION ER - TY - JOUR T1 - Age-Related Differences in Susceptibility to Carcinogenesis: a Quantitative Analysis of Empirical Animal Bioassay Data AN - 14703691; 10667547 AB - Results are presented from a statistically weighted analysis of relative cancer potency in terms of cancer transformations per animal per unit dose for animals in different age groups, scaled to the highest experimental dose used either in adult animals or the oldest age group of animals included in the experiment. Separate relative potency estimates were derived for the fetal, birthweaning, and weaning60-d periods. The databases used in the assessment are describe briefly, as are the modeling methods applied. Results are presented for overall continuous chemical, discrete chemical, and radiation dosing data sets; for mutagenic versus nonmutagenic chemicals; for male versus female animals; for rats versus mice; for direct-acting carcinogens versus agents requiring metabolic activation; for direct dosing in the birthweaning period versus dosing via lactation; and for liver tumors versus tumors in other organs. The results reveal a significant increased carcinogenic sensitivity in the birthweaning period per dose for mutagenic carcinogens and a somewhat smaller increase for radiation carcinogensis per gray. JF - Environmental Health Perspectives AU - Hattis, Dale AU - Goble, Robert AU - Russ, Abel AU - Chu, Margaret AU - Ericson, Jen Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1152 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CARCINOGENIC MECHANISMS KW - SUSCEPTIBILITY KW - BIOASSAY KW - MATHEMATIC MODELS, CARCINOGENESIS KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703691?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Age-Related+Differences+in+Susceptibility+to+Carcinogenesis%3A+a+Quantitative+Analysis+of+Empirical+Animal+Bioassay+Data&rft.au=Hattis%2C+Dale%3BGoble%2C+Robert%3BRuss%2C+Abel%3BChu%2C+Margaret%3BEricson%2C+Jen&rft.aulast=Hattis&rft.aufirst=Dale&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1152&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CARCINOGENIC MECHANISMS; SUSCEPTIBILITY; BIOASSAY; MATHEMATIC MODELS, CARCINOGENESIS; AGE COMPARISONS ER - TY - JOUR T1 - Increased Risk of Hepatocellular Carcinoma and Liver Cirrhosis in Vinyl Chloride Workers: Synergistic Effect of Occupational Exposure and Alcohol Intake AN - 14703681; 10667553 JF - Environmental Health Perspectives AU - Mastrangelo, Giuseppe AU - Fedeli, Ugo AU - Fadda, Emanuela AU - Valentini, Flavio AU - Agnesi, Roberto AU - Magarotto, Giancarlo AU - Marchi, Teresio Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1188 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - ALCOHOLS KW - SYNERGISTIC EFFECTS KW - HEALTH SAFETY, OCCUPATIONAL KW - VINYL CHLORIDE KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703681?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Increased+Risk+of+Hepatocellular+Carcinoma+and+Liver+Cirrhosis+in+Vinyl+Chloride+Workers%3A+Synergistic+Effect+of+Occupational+Exposure+and+Alcohol+Intake&rft.au=Mastrangelo%2C+Giuseppe%3BFedeli%2C+Ugo%3BFadda%2C+Emanuela%3BValentini%2C+Flavio%3BAgnesi%2C+Roberto%3BMagarotto%2C+Giancarlo%3BMarchi%2C+Teresio&rft.aulast=Mastrangelo&rft.aufirst=Giuseppe&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1188&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; HEALTH SAFETY, OCCUPATIONAL; VINYL CHLORIDE; HEPATOTOXICITY; ALCOHOLS; SYNERGISTIC EFFECTS ER - TY - JOUR T1 - Determinants of Bone and Blood Lead Levels Among Minorities Living in the Boston Area AN - 14703660; 10667546 AB - Blood and bone lead levels were measured in exclusively minority subjects living in the Boston, MA, area. In total, 84 subjects participated, and the mean and median blood Pb levels were 3.0 and 2.2 mu g/dl, respectively, while the mean tibia and patella Pb levels were 11.9 and 14.2 mu g/g, respectively. The associations between age and bone Pb biomarkers were found to be nonlinear, with higher levels found in subjects greater than 55 yr of age, and within the older age group, males exhibited a higher rate of blood and patella Pb accumulation than females. JF - Environmental Health Perspectives AU - Lin, Charles AU - Kim, Rokho AU - Tsaih, Shirng-Wern AU - Sparrow, David AU - Hu, Howard Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1147 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - MINORITIES KW - BLOOD LEAD LEVEL KW - MASSACHUSETTS KW - AGE COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703660?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Determinants+of+Bone+and+Blood+Lead+Levels+Among+Minorities+Living+in+the+Boston+Area&rft.au=Lin%2C+Charles%3BKim%2C+Rokho%3BTsaih%2C+Shirng-Wern%3BSparrow%2C+David%3BHu%2C+Howard&rft.aulast=Lin&rft.aufirst=Charles&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1147&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; MINORITIES; BLOOD LEAD LEVEL; MASSACHUSETTS; AGE COMPARISONS ER - TY - JOUR T1 - The Effect of Arsenic Mitigation Interventions on Disease Burden in Bangladesh AN - 14703547; 10667550 AB - In Bangladesh, mortality rates and disability-adjusted life years lost were calculated for arsenic-related disease and waterborne infectious disease to evaluate the possible change in overall disease burden resulting from the implementation of As mitigation interventions involving improvements in water supply and sanitation services. Results showed that much of the benefit obtained from intervention appeared to be negated by a concomitant increase in water-related infectious disease. JF - Environmental Health Perspectives AU - Lokuge, Kamalini M AU - Smith, Wayne AU - Caldwell, Bruce AU - Dear, Keith AU - Milton, Abul H Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1172 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 11 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MITIGATIVE MEASURES KW - ARSENIC KW - DISEASES AND DISORDERS KW - BANGLADESH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703547?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Effect+of+Arsenic+Mitigation+Interventions+on+Disease+Burden+in+Bangladesh&rft.au=Lokuge%2C+Kamalini+M%3BSmith%2C+Wayne%3BCaldwell%2C+Bruce%3BDear%2C+Keith%3BMilton%2C+Abul+H&rft.aulast=Lokuge&rft.aufirst=Kamalini&rft.date=2004-08-01&rft.volume=112&rft.issue=11&rft.spage=1172&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MITIGATIVE MEASURES; DISEASES AND DISORDERS; ARSENIC; BANGLADESH ER - TY - JOUR T1 - Biokinetics and Subchronic Toxic Effects of Oral Arsenite, Arsenate, Monomethylarsonic Acid, and Dimethylarsinic Acid in v-Ha-ras Transgenic (Tg.AC) Mice AN - 14703040; 10667802 AB - The effects of subchronic inorganic and organic arsenical exposure on the v-Ha-ras transgenic (Tg.AC) mouse liver were examined. Mice were assigned randomly to five groups that were provided unaltered drinking water or drinking water containing arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid at concentrations of 150, 200, 1500, and 1000 ppm as As, respectively, for 17 weeks. After four weeks of exposure, 12-O-tetradecanoylphorbol-13-acetate was applied twice weekly for two weeks to the shaved dorsal skin of all mice. Arsenic-induced toxicity was evidenced by an increase in moribundity and death, a depression in body weight, hepatic pathological changes, and significant changes in gene expression. Hepatic As accumulation, based on biokinetic analyses, was dose-dependent, and global DNA hypomethylation occurred after exposure to all four arsenicals. Among the 600 genes examined via microarry analysis, 70 displayed increased or decreased expression. All arsenicals produced increases in glutathione S-transferases and fibroblast growth factor 2, and a significant increase was observed in the expression of insulin-like growth factor binding protein 1 in monomethylarsonic acid-treated animals. JF - Environmental Health Perspectives AU - Xie, Yaxiong AU - Trouba, Kevin J AU - Liu, Jie AU - Waalkes, Michael P AU - Germolec, Dori R Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 1255 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 12 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ARSENATES KW - GENETICS, ANIMAL KW - ARSENIC KW - HEPATOTOXICITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biokinetics+and+Subchronic+Toxic+Effects+of+Oral+Arsenite%2C+Arsenate%2C+Monomethylarsonic+Acid%2C+and+Dimethylarsinic+Acid+in+v-Ha-ras+Transgenic+%28Tg.AC%29+Mice&rft.au=Xie%2C+Yaxiong%3BTrouba%2C+Kevin+J%3BLiu%2C+Jie%3BWaalkes%2C+Michael+P%3BGermolec%2C+Dori+R&rft.aulast=Xie&rft.aufirst=Yaxiong&rft.date=2004-08-01&rft.volume=112&rft.issue=12&rft.spage=1255&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GENETICS, ANIMAL; ARSENATES; ARSENIC; HEPATOTOXICITY ER - TY - JOUR T1 - Vaccines for other neonatal infections: Pneumococcal disease: a major global health problem of young children AN - 1257721744; 16614434 AB - Provided the high vaccine costs for pneumococcal conjugate vaccines can be addressed for the poorest countries, neonatal PCV immunization offers the hope of decreasing the significant morbidity that occurs in these vulnerable populations. JF - Expert Review of Vaccines AU - Richmond, Peter AD - University of WA School of Pediatrics and Child Health, Princess Margaret Hospital for Children, GPO Box D184, Perth WA 6840, Australia. peterrchr.uwa.edu.au Y1 - 2004/08// PY - 2004 DA - Aug 2004 SP - 379 EP - 382 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 3 IS - 4 SN - 1476-0584, 1476-0584 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Children KW - Health problems KW - Immunization KW - Infection KW - Morbidity KW - Neonates KW - Reviews KW - Vaccines KW - Vulnerability KW - immunization KW - Streptococcus pneumoniae KW - J 02350:Immunology KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257721744?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Vaccines&rft.atitle=Vaccines+for+other+neonatal+infections%3A+Pneumococcal+disease%3A+a+major+global+health+problem+of+young+children&rft.au=Richmond%2C+Peter&rft.aulast=Richmond&rft.aufirst=Peter&rft.date=2004-08-01&rft.volume=3&rft.issue=4&rft.spage=379&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Vaccines&rft.issn=14760584&rft_id=info:doi/10.1586%2F14760584.3.4.379 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2013-02-22 N1 - SubjectsTermNotLitGenreText - Reviews; Neonates; Vaccines; Children; Infection; Immunization; Morbidity; immunization; Health problems; Vulnerability; Streptococcus pneumoniae DO - http://dx.doi.org/10.1586/14760584.3.4.379 ER - TY - JOUR T1 - Table: Fiscal 2005 Defense Operation and Maintenance Budget and Military Personnel Budget; AN - 231471099 AB - Service___ Budget___ House ___ Senate ___ Conference Environmental restoration, Navy___ 266,820___ 266,820___ 447,820___ 266,820 Service___ Budget___ House ___ Senate ___ Conference JF - Aerospace Daily & Defense Report AU - U.S. Congress AD - U.S. Congress Y1 - 2004/07/29/ PY - 2004 DA - 2004 Jul 29 SP - 8 CY - Washington PB - Penton Media, Inc., Penton Business Media, Inc. VL - 211 IS - 1 SN - 15538591 KW - Aeronautics And Space Flight UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/231471099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabitrade&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerospace+Daily+%26+Defense+Report&rft.atitle=Table%3A+Fiscal+2005+Defense+Operation+and+Maintenance+Budget+and+Military+Personnel+Budget%3B&rft.au=U.S.+Congress&rft.aulast=U.S.+Congress&rft.aufirst=&rft.date=2004-07-29&rft.volume=211&rft.issue=1&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=Aerospace+Daily+%26+Defense+Report&rft.issn=15538591&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Name - Air National Guard N1 - Copyright - Copyright (c) 2004 The McGraw-Hill Companies, Inc. All rights reserved. N1 - Last updated - 2015-01-03 N1 - CODEN - ENVRAL ER - TY - JOUR T1 - Table: Fiscal 2005 Defense Appropriations Research, Development, Test and Evaluation; AN - 231588930 AB - Service___ Budget___ House ___ Senate ___ Conference Operational Test and Evaluation, Defense___ 305,135___ 309,135___ 305,135___ 314,835 JF - Aerospace Daily & Defense Report AU - U.S. Congress AD - U.S. Congress Y1 - 2004/07/28/ PY - 2004 DA - 2004 Jul 28 SP - 6 CY - Washington PB - Penton Media, Inc., Penton Business Media, Inc. VL - 211 IS - 19 SN - 15538591 KW - Aeronautics And Space Flight UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/231588930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabitrade&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerospace+Daily+%26+Defense+Report&rft.atitle=Table%3A+Fiscal+2005+Defense+Appropriations+Research%2C+Development%2C+Test+and+Evaluation%3B&rft.au=U.S.+Congress&rft.aulast=U.S.+Congress&rft.aufirst=&rft.date=2004-07-28&rft.volume=211&rft.issue=19&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Aerospace+Daily+%26+Defense+Report&rft.issn=15538591&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright (c) 2004 The McGraw-Hill Companies, Inc. All rights reserved. N1 - Last updated - 2015-01-03 N1 - CODEN - ENVRAL ER - TY - JOUR T1 - Fiscal 2005 Defense Appropriations Procurement; AN - 231527426 AB - Missiles___________________________1,398,321____1,327,000____1,378,321____1,307,000 Weapons, tracked combat vehicles___1,639,695____2,773,695____1,698,695____2,467,495 Total, Navy___27,714,444___28,353,273___28,238,598___28,650,534 JF - Aerospace Daily & Defense Report AU - U.S. Congress AD - U.S. Congress Y1 - 2004/07/26/ PY - 2004 DA - 2004 Jul 26 SP - 6 CY - Washington PB - Penton Media, Inc., Penton Business Media, Inc. VL - 211 IS - 17 SN - 15538591 KW - Aeronautics And Space Flight UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/231527426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aabitrade&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerospace+Daily+%26+Defense+Report&rft.atitle=Fiscal+2005+Defense+Appropriations+Procurement%3B&rft.au=U.S.+Congress&rft.aulast=U.S.+Congress&rft.aufirst=&rft.date=2004-07-26&rft.volume=211&rft.issue=17&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Aerospace+Daily+%26+Defense+Report&rft.issn=15538591&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright (c) 2004 The McGraw-Hill Companies, Inc. All rights reserved. N1 - Last updated - 2015-01-03 N1 - CODEN - ENVRAL ER - TY - JOUR T1 - An a posteriori strategy for enhancing gene discovery in anonymous cDNA microarray experiments AN - 18007709; 5956847 AB - MOTIVATION: Because of the high cost of sequencing, the bulk of gene discovery is performed using anonymous cDNA microarrays. Though the clones on such arrays are easier and cheaper to construct and utilize than unigene and oligonucleotide arrays, they are there in proportion to their corresponding gene expression activity in the tissue being examined. The associated redundancy will be there in any pool of possibly interesting differentially expressed clones identified in a microarray experiment for subsequent sequencing and investigation. An a posteriori sampling strategy is proposed to enhance gene discovery by reducing the impact of the redundancy in the identified pool. RESULTS: The proposed strategy exploits the fact that individual genes that are highly expressed in a tissue are more likely to be present as a number of spots in an anonymous library and, as a direct consequence, are also likely to give higher fluorescence intensity responses when present in a probe in a cDNA microarray experiment. Consequently, spots that respond with low intensities will have a lower redundancy and so should be sequenced in preference to those with the highest intensities. The proposed method, which formalizes how the fluorescence intensity of a spot should be assessed, is validated using actual microarray data, where the sequences of all the clones in the identified pool had been previously determined. For such validations, the concept of a repeat plot is introduced. It is also utilized to visualize and examine different measures for the characterization of fluorescence intensity. In addition, as confirmatory evidence, sequencing from the lowest to the highest intensities in a pool, with all the sequences known, is compared graphically with their random sequencing. The results establish that, in general, the opportunity for gene discovery is enhanced by avoiding the pooling of different biological libraries (because their construction will have involved different hybridization episodes) and concentrating on the clones with lower fluorescence intensities. JF - Bioinformatics AU - Anderssen, R S AU - Wu, Y AU - Dolferus, R AU - Saunders, I AD - CSIRO Mathematical and Information Sciences, GPO Box 664, Canberra ACT 2601, CSIRO Plant Industry and Cotton R&D Corporation and CSIRO Plant Industry and CRC for Sustainable Rice Production, GPO Box 1600, Canberra ACT 2601, Australia Y1 - 2004/07/22/ PY - 2004 DA - 2004 Jul 22 SP - 1721 EP - 1727 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 20 IS - 11 SN - 1367-4803, 1367-4803 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - Gene expression KW - Fluorescence KW - DNA microarrays KW - Hybridization analysis KW - N 14510:Occurrence, isolation & assay KW - W 30965:Miscellaneous, Reviews KW - W4 350:Bioinformatics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18007709?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioinformatics&rft.atitle=An+a+posteriori+strategy+for+enhancing+gene+discovery+in+anonymous+cDNA+microarray+experiments&rft.au=Anderssen%2C+R+S%3BWu%2C+Y%3BDolferus%2C+R%3BSaunders%2C+I&rft.aulast=Anderssen&rft.aufirst=R&rft.date=2004-07-22&rft.volume=20&rft.issue=11&rft.spage=1721&rft.isbn=&rft.btitle=&rft.title=Bioinformatics&rft.issn=13674803&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Fluorescence; Hybridization analysis; Gene expression; DNA microarrays ER - TY - JOUR T1 - Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GC x GC-TOFMS) for drug screening and confirmation. AN - 66686090; 15240028 AB - Comprehensive two-dimensional gas chromatography (GC x GC) is applied to analysis of drug standard mixtures containing 78 drugs of interest in forensic samples. For this study, underivatised drugs were employed. While several of the drugs were not detected at the low concentrations employed in the samples, most could be satisfactorily assigned their first and second dimension retentions in the GC x GC retention plane. For this study, time-of-flight mass spectrometry (TOFMS) detection was used. The enhanced separation possible in GC x GC is demonstrated, and typical linearity and apparatus precision are shown for tramadol, diazepam, olanzapine and desipramine using selected qualifier ions. Mass spectral library search quality for the detection of drugs in a selection of authentic forensic cases, along with retention position in the 2D retention plane, is used to support positive identification of the presence of the drugs. The analysis of 'difficult' drugs paracetamol and phenytoin is shown to produce anomalous chromatographic peak shape in the 2D plane, whereas most drugs gave acceptable peak shapes. The GC x GC technique was applied to screening drugs in forensic samples, with either flame ionisation (FID) or TOFMS detection, and compared favourably with conventional single column GC-MS analysis when tested for diazepam in an authentic forensic study. JF - Forensic science international AU - Song, Shin Miin AU - Marriott, Philip AU - Kotsos, Alex AU - Drummer, Olaf H AU - Wynne, Paul AD - Department of Applied Chemistry, Australian Centre for Research on Separation Science, Rmit University, Building 3, Bowen St., 124 Latrobe St., GPO Box 2476 V, Melbourne, Vic. 3001. Y1 - 2004/07/16/ PY - 2004 DA - 2004 Jul 16 SP - 87 EP - 101 VL - 143 IS - 2-3 SN - 0379-0738, 0379-0738 KW - Index Medicus KW - Substance-Related Disorders -- blood KW - Humans KW - Gas Chromatography-Mass Spectrometry -- methods KW - Forensic Medicine -- methods KW - Substance Abuse Detection -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66686090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forensic+science+international&rft.atitle=Comprehensive+two-dimensional+gas+chromatography+with+time-of-flight+mass+spectrometry+%28GC+x+GC-TOFMS%29+for+drug+screening+and+confirmation.&rft.au=Song%2C+Shin+Miin%3BMarriott%2C+Philip%3BKotsos%2C+Alex%3BDrummer%2C+Olaf+H%3BWynne%2C+Paul&rft.aulast=Song&rft.aufirst=Shin&rft.date=2004-07-16&rft.volume=143&rft.issue=2-3&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Forensic+science+international&rft.issn=03790738&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-11-01 N1 - Date created - 2004-07-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Money Laundering and Foreign Corruption: Enforcement and Effectiveness of the PATRIOT Act, Case Study Involving Riggs Bank AN - 1679125980; CL02834 AB - Demonstrates Riggs Bank's complicity in hiding Augusto Pinochet's accounts from law enforcement officials attempting to freeze his assets and other illegal and questionable acts. AU - United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations. Minority Staff AD - United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations. Minority Staff PY - 2004 SP - 22 KW - Banks KW - Congressional hearings KW - Corporate corruption KW - Crime KW - Equatorial Guinea KW - Frozen assets KW - Laundering of funds KW - Spain KW - United Kingdom UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1679125980?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Adnsa_cl&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=&rft.atitle=Money+Laundering+and+Foreign+Corruption%3A+Enforcement+and+Effectiveness+of+the+PATRIOT+Act%2C+Case+Study+Involving+Riggs+Bank&rft.au=United+States.+Congress.+Senate.+Committee+on+Governmental+Affairs.+Permanent+Subcommittee+on+Investigations.+Minority+Staff&rft.aulast=United+States.+Congress.+Senate.+Committee+on+Governmental+Affairs.+Permanent+Subcommittee+on+Investigations.+Minority+Staff&rft.aufirst=&rft.date=2004-07-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Digital National Security Archive N1 - Name - Althorp Investment Company, Ltd.; Ashburton Company, Ltd.; Riggs Bank, N.A.; United States. Department of the Treasury. Office of the Comptroller of the Currency N1 - Analyte descriptor - NSA document type: Report N1 - Last updated - 2015-06-16 ER - TY - JOUR T1 - Cultural and ethical issues in working with culturally diverse patients and their families: The use of the culturagram to promote cultural competent practice in health care settings AN - 210845268 AB - In all aspects of health and mental health care-the emergency room, the outpatient clinic, inpatient facilities, rehab centers, nursing homes, and hospices-social workers interact with patients from many different cultures. This paper will introduce an assessment tool for health care professionals to advance understanding of culturally diverse patients and their families. [PUBLICATION ABSTRACT] JF - Social Work in Health Care AU - Congress, Elaine P Y1 - 2004 PY - 2004 DA - 2004 SP - 249 EP - 262 CY - New York PB - Taylor & Francis Group VL - 39 IS - 3/4 SN - 00981389 KW - Social Services And Welfare KW - Ethics KW - Patients KW - Multiculturalism & pluralism KW - Health care KW - Families & family life UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/210845268?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apsychology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Work+in+Health+Care&rft.atitle=Cultural+and+ethical+issues+in+working+with+culturally+diverse+patients+and+their+families%3A+The+use+of+the+culturagram+to+promote+cultural+competent+practice+in+health+care+settings&rft.au=Congress%2C+Elaine+P&rft.aulast=Congress&rft.aufirst=Elaine&rft.date=2004-07-10&rft.volume=39&rft.issue=3%2F4&rft.spage=249&rft.isbn=&rft.btitle=&rft.title=Social+Work+in+Health+Care&rft.issn=00981389&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright Haworth Press, Inc. 2004 N1 - Last updated - 2010-06-08 N1 - CODEN - SWHCDO ER - TY - BOOK T1 - Report on the U.S. intelligence community's prewar intelligence assessments on Iraq: ordered reported on July 7, 2004 T2 - 108th Cong. AN - 58844469; 2004-0803220 AB - Presents US intelligence analysis of Iraq's programs for weapons of mass destruction (WMD), including nuclear, biological, and chemical weapons programs, delivery systems, and links to terrorism. JF - United States Senate, July 7 2004. Y1 - 2004/07/07/ PY - 2004 DA - 2004 Jul 07 PB - United States Senate KW - Weapons of mass destruction -- Iraq KW - Terrorism -- Iraq KW - Government investigations -- United States KW - Atomic weapons -- Iraq KW - Iraq -- Defenses KW - Chemical weapons -- Iraq KW - United States -- Intelligence service KW - Biological weapons -- Iraq UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58844469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2004-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Report+on+the+U.S.+intelligence+community%27s+prewar+intelligence+assessments+on+Iraq%3A+ordered+reported+on+July+7%2C+2004&rft.title=Report+on+the+U.S.+intelligence+community%27s+prewar+intelligence+assessments+on+Iraq%3A+ordered+reported+on+July+7%2C+2004&rft.issn=&rft_id=info:doi/ L2 - http://intelligence.senate.gov/iraqreport2.pdf LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Senate N1 - Document feature - table(s) N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Public water sources in rural watersheds of Nepal's Middle Mountains: issues and constraints. AN - 66898462; 15156351 AB - Inadequacy and poor quality of water supply for domestic purposes is increasingly becoming a concern in rural catchments of the Middle Mountains of Nepal. Water quantity is an issue in pocket areas of these catchments, while water quality is subject to concern in most of the water sources. Microbiological contamination in particular poses a risk to human health. In addition, sediment pollution during the monsoon season is perceived as an issue by the local residents. Elevated phosphate and nitrate levels in many water sources indicate intensive interaction with surface water hailing from agricultural areas and human settlements. These water quantity and quality concerns in two watersheds of Nepal, the Jhikhu Khola and the Yarsha Khola watersheds, are not isolated cases. Similar problems are reported from other watersheds monitored under the People and Resource Dynamics in Mountain Watersheds of the Hindu Kush-Himalayas (PARDYP) project in China, India, and Pakistan and the literature of this region. JF - Environmental management AU - Merz, Juerg AU - Nakarmi, Gopal AU - Shrestha, Smita AU - Dahal, Bed M AU - Dongol, Bhawani S AU - Schaffner, Monika AU - Shakya, Sangeeta AU - Sharma, Subodh AU - Weingartner, Rolf AD - PARDYP/International Centre for Integrated Mountain Development, GPO Box 3226, Kathmandu, Nepal. jmerz@icimod.org.np Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 26 EP - 37 VL - 34 IS - 1 SN - 0364-152X, 0364-152X KW - Water Pollutants KW - 0 KW - Index Medicus KW - Environmental Monitoring KW - Altitude KW - Humans KW - Data Collection KW - Water Microbiology KW - Geologic Sediments KW - Nepal KW - Water Supply -- economics KW - Public Sector KW - Water Pollutants -- analysis KW - Water Supply -- standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66898462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+management&rft.atitle=Public+water+sources+in+rural+watersheds+of+Nepal%27s+Middle+Mountains%3A+issues+and+constraints.&rft.au=Merz%2C+Juerg%3BNakarmi%2C+Gopal%3BShrestha%2C+Smita%3BDahal%2C+Bed+M%3BDongol%2C+Bhawani+S%3BSchaffner%2C+Monika%3BShakya%2C+Sangeeta%3BSharma%2C+Subodh%3BWeingartner%2C+Rolf&rft.aulast=Merz&rft.aufirst=Juerg&rft.date=2004-07-01&rft.volume=34&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Environmental+management&rft.issn=0364152X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-10-18 N1 - Date created - 2004-09-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - [Polyfection as nonviral gene transfer method -design of novel nonviral vector using alpha-cyclodextrin]. AN - 66680988; 15235229 AB - Due to the growing concerns over the toxicity and immunogenicity of viral DNA delivery systems, DNA delivery via nonviral routes has become more desirable and advantageous. In particular, polycation complexes with DNA (polyplex) are attractive nonviral vectors. To design novel polycationic vectors, we prepared polyamidoamine starburst dendrimer (dendrimer) conjugates with three cyclodextrins (CDE conjugates) and three generations (G2, G3, and G4) of dendrimers. Of seven CDE conjugates, an alpha-CDE conjugate (G3) with an average degree of substitution (DS) of alpha-CyD of 2.4 [alpha-CDE conjugate (G3, DS 2.4)] showed greater gene transfer activity than dendrimers and other alpha-CDE conjugates with less cytotoxicity. These results suggest the potential use of alpha-CDE conjugate (G3, DS 2.4) as a polycationic vector in vitro and in vivo. Herein, I review a recent polyfection method, with special focus on alpha-CDE conjugate (G3, DS 2.4). JF - Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan AU - Arima, Hidetoshi AD - Graduate School of Pharmaceutical Sciences, Kumamoto University, Japan. arimah@gpo.kumamoto-u.ac.jp Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 451 EP - 464 VL - 124 IS - 7 SN - 0031-6903, 0031-6903 KW - Cyclodextrins KW - 0 KW - Dendrimers KW - PAMAM Starburst KW - Polyamines KW - alpha-Cyclodextrins KW - polycations KW - alpha-cyclodextrin KW - Z1LH97KTRM KW - Index Medicus KW - Gene Transfer Techniques KW - Genetic Vectors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66680988?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Yakugaku+zasshi+%3A+Journal+of+the+Pharmaceutical+Society+of+Japan&rft.atitle=%5BPolyfection+as+nonviral+gene+transfer+method+-design+of+novel+nonviral+vector+using+alpha-cyclodextrin%5D.&rft.au=Arima%2C+Hidetoshi&rft.aulast=Arima&rft.aufirst=Hidetoshi&rft.date=2004-07-01&rft.volume=124&rft.issue=7&rft.spage=451&rft.isbn=&rft.btitle=&rft.title=Yakugaku+zasshi+%3A+Journal+of+the+Pharmaceutical+Society+of+Japan&rft.issn=00316903&rft_id=info:doi/ LA - Japanese DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-27 N1 - Date created - 2004-07-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Changes in ion fluxes during phototropic bending of etiolated oat coleoptiles. AN - 66652849; 15155378 AB - This work has been conducted to assist theoretical modelling of the different stages of the blue light (BL)-induced phototropic signalling pathway and ion transport activity across plant membranes. Ion fluxes (Ca(2+), H(+), K(+) and Cl(-)) in etiolated oat coleoptiles have been measured continuously before and during unilateral BL exposure. Changes in ion fluxes at the illuminated (light) and shadowed (dark) sides of etiolated oat coleoptiles (Avena sativa) were studied using a non-invasive ion-selective microelectrode technique (MIFE). The bending response was also measured continuously, and correlations between the changes in various ion fluxes and bending response have been investigated. For each ion the difference (Delta) between the magnitudes of flux at the light and dark sides of the coleoptile was calculated. Plants that demonstrated a phototropic bending response also demonstrated Ca(2+) influx into the light side approximately 20 min after the start of BL exposure. This is regarded as part of the perception and transduction stages of the BL-induced signal cascade. The first 10 min of bending were associated with substantial influx of H(+), K(+) and Cl(-) into the light (concave) side of the coleoptiles. The data suggest that Ca(2+) participates in the signalling stage of the BL-induced phototropism, whereas the phototropic bending response is linked to changes in the transport of H(+), K(+) and Cl(-). JF - Annals of botany AU - Babourina, Olga AU - Godfrey, Leith AU - Voltchanskii, Konstantin AD - School of Mathematics and Physics, University of Tasmania, GPO Box 252-21, Hobart, Tasmania 7001, Australia. obabouri@agric.uwa.edu.au Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 187 EP - 194 VL - 94 IS - 1 SN - 0305-7364, 0305-7364 KW - Chlorine KW - 4R7X1O2820 KW - Hydrogen KW - 7YNJ3PO35Z KW - Potassium KW - RWP5GA015D KW - Calcium KW - SY7Q814VUP KW - Index Medicus KW - Darkness KW - Calcium -- metabolism KW - Hydrogen -- metabolism KW - Light KW - Cell Membrane -- metabolism KW - Time Factors KW - Chlorine -- metabolism KW - Signal Transduction KW - Potassium -- metabolism KW - Models, Theoretical KW - Phototropism KW - Cotyledon -- growth & development KW - Avena -- metabolism KW - Avena -- growth & development KW - Cotyledon -- radiation effects KW - Avena -- radiation effects KW - Cotyledon -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66652849?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+botany&rft.atitle=Changes+in+ion+fluxes+during+phototropic+bending+of+etiolated+oat+coleoptiles.&rft.au=Babourina%2C+Olga%3BGodfrey%2C+Leith%3BVoltchanskii%2C+Konstantin&rft.aulast=Babourina&rft.aufirst=Olga&rft.date=2004-07-01&rft.volume=94&rft.issue=1&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Annals+of+botany&rft.issn=03057364&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-09-24 N1 - Date created - 2004-06-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Why We Must End Insurance Discrimination against Mental Health Care AN - 60725282; 200503271 AB - In this Policy Essay, Representative Patrick Kennedy argues that insurance discrimination against those suffering from mental illnesses constitutes a serious & often overlooked deficiency of the modern American health care system. While the Mental Health Parity Act of 1996 was an important step toward resolution of this issue, many loopholes remain that allow insurance companies to deny much-needed coverage to those suffering from such illnesses. This Essay details how improving access to health insurance for the mentally ill is not only socially beneficial, but also economically sound; the cost of instituting mental health parity is far outweighed by the costs that employers bear because of the reduced productivity of untreated mental illness sufferers. Representative Kennedy recommends that these problems may be addressed by additional mental health parity legislation -- specifically, the proposed Paul Wellstone Act. Adapted from the source document. JF - Harvard Journal on Legislation AU - Kennedy, Patrick J AD - United States House of Representatives Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 363 EP - 375 VL - 41 IS - 2 SN - 0017-808X, 0017-808X KW - Health Care Services Policy KW - Mental Patients KW - Health Insurance KW - Discrimination KW - Mental Health Services KW - Legislation KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60725282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harvard+Journal+on+Legislation&rft.atitle=Why+We+Must+End+Insurance+Discrimination+against+Mental+Health+Care&rft.au=Kennedy%2C+Patrick+J&rft.aulast=Kennedy&rft.aufirst=Patrick&rft.date=2004-07-01&rft.volume=41&rft.issue=2&rft.spage=363&rft.isbn=&rft.btitle=&rft.title=Harvard+Journal+on+Legislation&rft.issn=0017808X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Mental Health Services; Health Insurance; Mental Patients; Discrimination; Legislation; Health Care Services Policy ER - TY - JOUR T1 - Commerce with a Conscience: Balancing Privacy and Profit in a Digital World AN - 60695673; 200503300 AB - In this Policy Essay, Representative Edward J. Markey discusses changes in regulations governing patient privacy that have been recently implemented by the Department of Heath & Human Services. Representative Markey argues that in the areas of patient consent & marketing, these changes have favored business interests at the expense of patient privacy. To correct this imbalance Representative Markey argues that Congress should pass the STOHP Act, which would protect patient privacy by restoring consent requirements & limitations on marketing by health care providers. Adapted from the source document. JF - Harvard Journal on Legislation AU - Markey, Edward J AD - United States House of Representatives Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 377 EP - 388 VL - 41 IS - 2 SN - 0017-808X, 0017-808X KW - Patients Rights KW - Privacy KW - Informed Consent KW - Health Policy KW - Legislation KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60695673?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harvard+Journal+on+Legislation&rft.atitle=Commerce+with+a+Conscience%3A+Balancing+Privacy+and+Profit+in+a+Digital+World&rft.au=Markey%2C+Edward+J&rft.aulast=Markey&rft.aufirst=Edward&rft.date=2004-07-01&rft.volume=41&rft.issue=2&rft.spage=377&rft.isbn=&rft.btitle=&rft.title=Harvard+Journal+on+Legislation&rft.issn=0017808X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Patients Rights; Privacy; Informed Consent; Health Policy; Legislation ER - TY - JOUR T1 - Collaboration as a Means to Formulating Mutually Beneficial Environmental Policy AN - 60680210; 200503193 AB - In this Policy Essay, United States Senator Mike Crapo discusses the value of local collaboration in the development of mutually beneficial environmental policy. Using two examples of collaborative efforts in ID, Senator Crapo argues that policy development through collaboration at the local level is more efficient, avoids litigation, increases access to decision making, & leads to more stable policy. Adapted from the source document. JF - Harvard Journal on Legislation AU - Crapo, Mike AD - United States Senate Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 351 EP - 361 VL - 41 IS - 2 SN - 0017-808X, 0017-808X KW - Idaho KW - Policy Making KW - Cooperation KW - Environmental Policy KW - article KW - 9261: public policy/administration; public policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60680210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Harvard+Journal+on+Legislation&rft.atitle=Collaboration+as+a+Means+to+Formulating+Mutually+Beneficial+Environmental+Policy&rft.au=Crapo%2C+Mike&rft.aulast=Crapo&rft.aufirst=Mike&rft.date=2004-07-01&rft.volume=41&rft.issue=2&rft.spage=351&rft.isbn=&rft.btitle=&rft.title=Harvard+Journal+on+Legislation&rft.issn=0017808X&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Policy Making; Environmental Policy; Cooperation; Idaho ER - TY - JOUR T1 - Ahmad Chalabi: "The Biggest Error Was Occupation" AN - 60676521; 200500702 AB - An interview with Iraqi National Congress leader Ahmad Chalabi that addresses the future development of Iraq, the US's involvement in Iraqi liberation, the process of de-Baathification in Iraq, the international community's accusations of wrongdoing against Chalabi, & the extent of corruption in the UN oil-for-food program in Iraq is presented. Questions concerning whether Iraq's interim government will engender a legitimate democracy, minority groups' right to self-determination, & the formation of Iraq's legislature are addressed. It is contended that the US should not have occupied Iraq following Operation Iraqi Freedom & that a provisional Iraqi government should have been established prior to the ousting of Saddam Hussein. The issue of whether de-Baathification processes have been responsible for rebel insurgency throughout Iraq is then pondered. After exploring Chalabi's relations with Hussein following the US's capture of the latter, the international community's charges that Chalabi engaged in embezzlement & falsified reports of the Hussein regime's possession of weapons of mass destruction are countered. In addition, it is stated that Paul Bremer actually prevented the Iraqi Interim Government Council's examination of whether the United Nation's oil-for-food program in Iraq was indeed corrupt. J. W. Parker JF - Middle East Quarterly AU - Chalabi, Ahmad AD - Iraqi National Congress Y1 - 2004/07// PY - 2004 DA - July 2004 SP - 69 EP - 77 VL - 11 IS - 3 SN - 1073-9467, 1073-9467 KW - Weapons KW - War KW - United States of America KW - Corruption KW - United Nations KW - Political Development KW - Iraq KW - article KW - 9063: international relations; international relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60676521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Middle+East+Quarterly&rft.atitle=Ahmad+Chalabi%3A+%22The+Biggest+Error+Was+Occupation%22&rft.au=Chalabi%2C+Ahmad&rft.aulast=Chalabi&rft.aufirst=Ahmad&rft.date=2004-07-01&rft.volume=11&rft.issue=3&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Middle+East+Quarterly&rft.issn=10739467&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - SuppNotes - Interview conducted by Michael Rubin. N1 - Last updated - 2016-09-28 N1 - CODEN - MEQUFZ N1 - SubjectsTermNotLitGenreText - Iraq; United States of America; War; United Nations; Corruption; Weapons; Political Development ER - TY - JOUR T1 - Minority's Status Laws in the European Union and in Hungary AN - 36549165; 3360710 JF - Central European political science review AU - Ieda, Osamu AU - Kántor, Zoltán AU - Schöpflin, György AU - Csergo, Zsuzsa AU - Goldgeier, James M AU - Halász, Iván AU - Majtényi, Balázs AU - Vízi, Balázs AD - European Parliament ; George Washington University ; Library of Congress ; Eötvös Lóránd University ; Eötvös Loránd University ; Corvinus University of Budapest Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 7 EP - 91 VL - 5 IS - 16 SN - 1586-4197, 1586-4197 KW - Political Science KW - Citizenship KW - Member states KW - Ethnicity KW - International law KW - Ethnic origin KW - Europe KW - Nationalism KW - Nation building KW - Post-communist societies KW - Hungary KW - European Union KW - Minority rights KW - European studies KW - Legislation KW - Domestic policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36549165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Central+European+political+science+review&rft.atitle=Minority%27s+Status+Laws+in+the+European+Union+and+in+Hungary&rft.au=Ieda%2C+Osamu%3BK%C3%A1ntor%2C+Zolt%C3%A1n%3BSch%C3%B6pflin%2C+Gy%C3%B6rgy%3BCsergo%2C+Zsuzsa%3BGoldgeier%2C+James+M%3BHal%C3%A1sz%2C+Iv%C3%A1n%3BMajt%C3%A9nyi%2C+Bal%C3%A1zs%3BV%C3%ADzi%2C+Bal%C3%A1zs&rft.aulast=Ieda&rft.aufirst=Osamu&rft.date=2004-07-01&rft.volume=5&rft.issue=16&rft.spage=7&rft.isbn=&rft.btitle=&rft.title=Central+European+political+science+review&rft.issn=15864197&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Collection of 7 articles N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 4541 1247; 9923 11979; 8131 11032 9705; 4435; 4429; 2280 2309 11032 9705; 8536; 7321; 3706 5574 10472; 4529 4534 10721 6737 4539 10727 9030; 7919 6772 9030; 8477 8476; 6743 7253; 171 87 129; 129 ER - TY - JOUR T1 - Virtual nationalism in comparative context: how unique is the Hungarian approach? AN - 36541190; 3360656 JF - Central European political science review AU - Csergo, Zsuzsa AU - Goldgeier, James M AD - George Washington University ; Library of Congress Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 40 EP - 56 VL - 5 IS - 16 SN - 1586-4197, 1586-4197 KW - Political Science KW - Citizenship KW - European law KW - Nationalism KW - Nation building KW - Post-communist societies KW - Hungary KW - European Union KW - Romania KW - Minority rights KW - European studies KW - Russia KW - Legislation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36541190?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Central+European+political+science+review&rft.atitle=Virtual+nationalism+in+comparative+context%3A+how+unique+is+the+Hungarian+approach%3F&rft.au=Csergo%2C+Zsuzsa%3BGoldgeier%2C+James+M&rft.aulast=Csergo&rft.aufirst=Zsuzsa&rft.date=2004-07-01&rft.volume=5&rft.issue=16&rft.spage=40&rft.isbn=&rft.btitle=&rft.title=Central+European+political+science+review&rft.issn=15864197&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 4541 1247; 9923 11979; 8536; 8131 11032 9705; 2280 2309 11032 9705; 7321; 8477 8476; 4529 4534 10721 6737 4539 10727 9030; 4536 7253 4529 4534 10721 6737 4539 10727 9030; 171 87 129; 352 119 129; 349 394 129 ER - TY - JOUR T1 - An Unrecognized Source of PCB Contamination in Schools and Other Buildings AN - 21348554; 7697185 AB - An investigation of 24 buildings in the Greater Boston Area revealed that one-third (8 of 24) contained caulking materials with polychlorinated biphenyl (PCB) content exceeding 50 ppm by weight, which is the U.S. Environmental Protection Agency (U.S. EPA) specified limit above which this material is considered to be PCB bulk product waste. These buildings included schools and other public buildings. In a university building where similar levels of PCB were found in caulking material, PCB levels in indoor air ranged from 111 to 393 ng/m super(3); and in dust taken from the building ventilation system, < 1 ppm to 81 ppm. In this building, the U.S. EPA mandated requirements for the removal and disposal of the PCB bulk product waste as well as for confirmatory sampling to ensure that the interior and exterior of the building were decontaminated. Although U.S. EPA regulations under the Toxic Substances Control Act stipulate procedures by which PCB-contaminated materials must be handled and disposed, the regulations apparently do not require that materials such as caulking be tested to determine its PCB content. This limited investigation strongly suggests that were this testing done, many buildings would be found to contain high levels of PCBs in the building materials and potentially in the building environment. The presence of PCBs in schools is of particular concern given evidence suggesting that PCBs are developmental toxins. JF - Environmental Health Perspectives AU - Herrick, Robert F AU - McClean, Michael D AU - Meeker, John D AU - Baxter, Lisa K AU - Weymouth, George A AD - super(1)Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1051 EP - 1053 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts KW - Ventilation KW - Contamination KW - Toxic substances KW - Dust KW - USA, Massachusetts, Boston KW - schools KW - Waste disposal KW - PCB compounds KW - public buildings KW - Construction materials KW - Buildings KW - Toxins KW - EPA KW - Indoor environments KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21348554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=An+Unrecognized+Source+of+PCB+Contamination+in+Schools+and+Other+Buildings&rft.au=Herrick%2C+Robert+F%3BMcClean%2C+Michael+D%3BMeeker%2C+John+D%3BBaxter%2C+Lisa+K%3BWeymouth%2C+George+A&rft.aulast=Herrick&rft.aufirst=Robert&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1051&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.6912 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA, Massachusetts, Boston; PCB compounds; Buildings; EPA; schools; public buildings; Toxic substances; Toxins; Indoor environments; Contamination; Construction materials; Ventilation; Dust; Waste disposal DO - http://dx.doi.org/10.1289/ehp.6912 ER - TY - JOUR T1 - Temporal constraints on Palaeoproterozoic eclogite formation and exhumation (Usagaran Orogen, Tanzania) AN - 21343041; 5984601 AB - In-situ rock suites that preserve assemblages consistent with metamorphism to eclogite-facies conditions are absent from the Archaean. Their Palaeoproterozoic appearance is one of the markers of the onset of tectonic processes similar to those seen in the Phanerozoic Earth. We report new U-Pb Secondary Ion Mass Spectrometry (SIMS) zircon data from the oldest known eclogites (the ~2.0 Ga Usagaran eclogites, Tanzania) that constrain the timing of high-grade metamorphism, deformation and exhumation of these eclogites and constrain the speed of these processes at this critical period in Earth history. Direct dating of metamorphic zircon from mafic eclogites, and isostructurally recrystallised zircon rims from pelites and felsic gneisses indicates that high- grade metamorphism occurred at 1999.1+/-1.1 Ma. The rocks were quickly cooled and exhumed at rates of ~25 C/Ma and 0.06-0.22 GPa/Ma, respectively, at least in part, by amphibolite-facies sinistral transpression constrained by a 1991+/-2 Ma pegmatite dyke that crosscuts foliation. Detrital zircons in metasedimentary gneiss protoliths were dominantly derived from two sources: (1) the Tanzanian craton, and (2) a 2400-2640 Ma source region that is compatible with a belt of reworked Archaean and Palaeoproterozoic rocks that lie in the East African Orogen. JF - Earth and Planetary Science Letters AU - Collins, A S AU - Reddy, S M AU - Buchan, C AU - Mruma, A AD - Tectonics SRC, Department of Applied Geology, Curtin University of Technology, GPO Box U1987, Perth WA 6845, Australia, acollins@tsrc.uwa.edu.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 175 EP - 192 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 224 IS - 1-2 SN - 0012-821X, 0012-821X KW - Microbiology Abstracts B: Bacteriology KW - eclogite KW - Palaeoproterozoic KW - SHRIMP KW - U-Pb isotopes KW - Usagaran Orogen KW - exhumation KW - zircon KW - dating deformation KW - Tanzania KW - geochronology KW - Data processing KW - Dating KW - Critical period KW - Mass spectroscopy KW - J 02490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21343041?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Earth+and+Planetary+Science+Letters&rft.atitle=Temporal+constraints+on+Palaeoproterozoic+eclogite+formation+and+exhumation+%28Usagaran+Orogen%2C+Tanzania%29&rft.au=Collins%2C+A+S%3BReddy%2C+S+M%3BBuchan%2C+C%3BMruma%2C+A&rft.aulast=Collins&rft.aufirst=A&rft.date=2004-07-01&rft.volume=224&rft.issue=1-2&rft.spage=175&rft.isbn=&rft.btitle=&rft.title=Earth+and+Planetary+Science+Letters&rft.issn=0012821X&rft_id=info:doi/10.1016%2Fj.epsl.2004.04.027 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Data processing; Dating; Critical period; Mass spectroscopy DO - http://dx.doi.org/10.1016/j.epsl.2004.04.027 ER - TY - JOUR T1 - Book Review. Albert R. Roberts and Kenneth R. Yeager (Eds). Evidence-Based Practice Manual: Research and Outcome Measures in Health and Human Services. New York: Oxford University Press, 2004. 1092 pp. ISBN 0-19-516500-4, $89.50 (hardback). AN - 204718833 JF - Brief Treatment and Crisis Intervention AU - Congress, Elaine P Y1 - 2004///Summer PY - 2004 DA - Summer 2004 SP - 195 CY - Cary PB - Oxford Publishing Limited(England) VL - 4 IS - 2 SN - 14743310 KW - Medical Sciences--Psychiatry And Neurology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/204718833?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthcompleteshell&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Brief+Treatment+and+Crisis+Intervention&rft.atitle=Book+Review.+Albert+R.+Roberts+and+Kenneth+R.+Yeager+%28Eds%29.+Evidence-Based+Practice+Manual%3A+Research+and+Outcome+Measures+in+Health+and+Human+Services.+New+York%3A+Oxford+University+Press%2C+2004.+1092+pp.+ISBN+0-19-516500-4%2C+%2489.50+%28hardback%29.&rft.au=Congress%2C+Elaine+P&rft.aulast=Congress&rft.aufirst=Elaine&rft.date=2004-07-01&rft.volume=4&rft.issue=2&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Brief+Treatment+and+Crisis+Intervention&rft.issn=14743310&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Copyright - Copyright Oxford University Press(England) Summer 2004 N1 - Last updated - 2010-06-07 ER - TY - JOUR T1 - Sinorhizobium meliloti metabolism in the root nodule: A proteomic perspective AN - 18041715; 5989534 AB - The proteome of the model symbiotic bacterium, Sinorhizobium meliloti was examined to determine the enzymatic reactions and cell processes that occur when S. meliloti occupies the root nodules of Medicago truncatula and Melilotus alba. The proteomes of the nodule bacteria were compared to that of S. meliloti grown under laboratory cultured conditions as an additional control. All the detectable protein spots on the two-dimensional (2-D) gels between pH 4-7 were analyzed. In total, the identity of proteins in 1545 spots from 2-D gels was determined using peptide mass fingerprinting. There were clear differences in the proteome of nodule bacteria and cultured bacteria and putative nodule-specific and nodule suppressed proteins were identified. The data were analyzed using metabolic pathway prediction programs and used to review the biochemical and genetic studies that had been done previously on S. meliloti over several decades. There was a broad congruency between the proteomic and biochemical data when the overall pathways of central carbon and nitrogen metabolism were considered. A selective suite of ABC-type transporters was present in nodule bacteria that were biased towards the transport of amino acids and inorganic ions (P and Fe) suggesting that a highly specialized nutrient exchange was occurring between the nodule bacteria and the host. Proteins prominent in nodule bacteria were those involved in the pathways for vitamin synthesis and stress-related processes (chaperoning, heat shock, detoxification of reactive oxygen species, regulation of stress and osmo-regulation). Some of these proteins were found only in nodule bacteria. These results show the extent of the shift in metabolism that occurs when S. meliloti invades legume plants and establishes a nitrogen fixing symbiosis. JF - Proteomics AU - Djordjevic, MA AD - ARC Centre of Excellence for Integrative Legume Research, Genomic Interactions Group, Research School of Biological Sciences, Australian National University, GPO Box 475, Canberra, ACT, 2601, Australia, michael@rsbs.anu.edu.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1859 EP - 1872 VL - 4 IS - 7 SN - 1615-9853, 1615-9853 KW - Microbiology Abstracts B: Bacteriology KW - proteomes KW - Symbionts KW - Nitrogen fixation KW - Rhizosphere KW - Roots KW - Sinorhizobium meliloti KW - Medicago truncatula KW - Nodules KW - J 02901:Soil and plants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18041715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proteomics&rft.atitle=Sinorhizobium+meliloti+metabolism+in+the+root+nodule%3A+A+proteomic+perspective&rft.au=Djordjevic%2C+MA&rft.aulast=Djordjevic&rft.aufirst=MA&rft.date=2004-07-01&rft.volume=4&rft.issue=7&rft.spage=1859&rft.isbn=&rft.btitle=&rft.title=Proteomics&rft.issn=16159853&rft_id=info:doi/10.1002%2Fpmic.200300802 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Sinorhizobium meliloti; Medicago truncatula; Nodules; Rhizosphere; Roots; proteomes; Symbionts; Nitrogen fixation DO - http://dx.doi.org/10.1002/pmic.200300802 ER - TY - JOUR T1 - Protein extraction from mature rice leaves for two-dimensional gel electrophoresis and its application in proteome analysis AN - 17752315; 5989537 AB - Sample preparation is crucial for extraction and higher resolution of proteins by two-dimensional gel electrophoresis (2-DE). In this study, we present an efficient protocol to extract proteins from mature rice leaves by minimizing the presence of nonprotein contaminants and by maximizing contact between the sample and extraction buffer. A combination of chemical and physical processes remarkably improved protein extraction for 2-DE. The efficiency of this protocol was demonstrated by comparison of the rice proteome at two developmental stages. JF - Proteomics AU - Islam, N AU - Lonsdale, M AU - Upadhyaya, N M AU - Higgins, T J AU - Hirano, H AU - Akhurst, R AD - CSIRO, Entomology, GPO Box 1700, Canberra ACT 2601, Australia, naz.islam@csiro.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1903 EP - 1908 VL - 4 IS - 7 SN - 1615-9853, 1615-9853 KW - Rice KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts KW - Buffers KW - Leaves KW - Developmental stages KW - Oryza sativa KW - proteomics KW - Contaminants KW - Gel electrophoresis KW - W2 32250:Others KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17752315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proteomics&rft.atitle=Protein+extraction+from+mature+rice+leaves+for+two-dimensional+gel+electrophoresis+and+its+application+in+proteome+analysis&rft.au=Islam%2C+N%3BLonsdale%2C+M%3BUpadhyaya%2C+N+M%3BHiggins%2C+T+J%3BHirano%2C+H%3BAkhurst%2C+R&rft.aulast=Islam&rft.aufirst=N&rft.date=2004-07-01&rft.volume=4&rft.issue=7&rft.spage=1903&rft.isbn=&rft.btitle=&rft.title=Proteomics&rft.issn=16159853&rft_id=info:doi/10.1002%2Fpmic.200300816 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Oryza sativa; Gel electrophoresis; Leaves; Contaminants; proteomics; Developmental stages; Buffers DO - http://dx.doi.org/10.1002/pmic.200300816 ER - TY - JOUR T1 - Two major classes of target site insensitivity mutations confer resistance to organophosphate and carbamate insecticides AN - 17593369; 5962355 AB - Interspecific comparisons of bioassay and biochemical data suggest two major patterns of target site resistance to carbamates and organophosphates. Pattern I resistance, which is generally more effective for carbamates, has been shown in two sub-species of mosquitoes to be due to a particular Gly-Ser mutation in the oxyanion hole within the active site of one of their two acetylcholinesterase enzymes. Intriguingly, different substitutions at the equivalent site confer organophosphate hydrolytic ability on other esterases responsible for metabolic resistance in some other species. In the case of the aphid, Myzus persicae, Pattern I resistance is due to a Ser-Phe mutation in the vicinity of the acyl pocket of acetylcholinesterase. Pattern II resistance is at least as effective for organophosphates as it is for carbamates and may even be specific to organophosphates in some cases. Molecular studies on this pattern of resistance in three higher Diptera show that it is due to changes that constrict the acetylcholinesterase active site gorge and limit binding of the insecticide to the catalytic residues at the base of the gorge. One case of Pattern II resistance in the mosquito, Culex tritaeniorhynchus, involves the same site near the acyl pocket of acetylcholinesterase, albeit a different substitution, as that involved in Pattern I resistance in M. persicae. JF - Pesticide Biochemistry and Physiology AU - Russell, R J AU - Claudianos, C AU - Campbell, P M AU - Horne, I AU - Sutherland, T D AU - Oakeshott, JG AD - CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia, Robyn.Russell@csiro.au Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 84 EP - 93 PB - Elsevier Inc. VL - 79 IS - 3 SN - 0048-3575, 0048-3575 KW - Aphids KW - Homoptera KW - ASFA 3: Aquatic Pollution & Environmental Quality; Entomology Abstracts KW - Z 05215:Mutation KW - Q5 01504:Effects on organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17593369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pesticide+Biochemistry+and+Physiology&rft.atitle=Two+major+classes+of+target+site+insensitivity+mutations+confer+resistance+to+organophosphate+and+carbamate+insecticides&rft.au=Russell%2C+R+J%3BClaudianos%2C+C%3BCampbell%2C+P+M%3BHorne%2C+I%3BSutherland%2C+T+D%3BOakeshott%2C+JG&rft.aulast=Russell&rft.aufirst=R&rft.date=2004-07-01&rft.volume=79&rft.issue=3&rft.spage=84&rft.isbn=&rft.btitle=&rft.title=Pesticide+Biochemistry+and+Physiology&rft.issn=00483575&rft_id=info:doi/10.1016%2Fj.pestbp.2004.03.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-12-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.pestbp.2004.03.002 ER - TY - JOUR T1 - Effect Measures in Prevalence Studies AN - 14706642; 10665547 AB - The relationship between indices and prevalence studies is reviewed briefly, and the relative merits of using prevalence odds ratios and prevalence ratios are elucidated and discussed, arguing that prevalence odds ratios should continue to be one of the standard methods for analyzing such studies. Three arguments are offered for use of the prevalence odds ratio: it estimates the incidence rate ratio with fewer assumptions than required for the prevalence ratio; it can be estimated using the same methods as for the odds ratio in casecontrol studies; and it provides practical, analytical, and theoretical consistency between analyses of a prevalence study and those of a prevalence casecontrol study. JF - Environmental Health Perspectives AU - Pearce, Neil Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1047 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - DISEASES AND DISORDERS KW - PUBLIC HEALTH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706642?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effect+Measures+in+Prevalence+Studies&rft.au=Pearce%2C+Neil&rft.aulast=Pearce&rft.aufirst=Neil&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1047&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; DISEASES AND DISORDERS; PUBLIC HEALTH ER - TY - JOUR T1 - Biomarkers in Maternal and Newborn Blood Indicate Heightened Fetal Susceptibility to Procarcinogenic DNA Damage AN - 14706171; 10665562 AB - Pregnant minority women living in New York City were studied to explore the relationship between maternal exposure to PAHs and environmental tobacco smoke, and fetal susceptibility to procarcinogenic DNA damage. Carcinogenic DNA adducts and cotinine were compared in paired blood samples collected from mothers and newborns. The levels of DNA damage from PAHs in white blood cells were higher than expected in newborns compared with the paired mothers. Detectable adducts were found in 34% of newborns whose mothers had nondetectable levels of adducts, while 30% of mothers with detectable adducts had newborns with nondetectable levels of adducts. While levels of adducts in paired newbornmaternal samples were modestly but significantly correlated, as were cotinine levels, DNA adducts were not correlated significantly with cotinine in either maternal or newborn samples. Environmental tobacco smoke was correlated significantly with cotinine in both maternal and newborn samples, but dietary PAHs and environmental tobacco smoke were not associated significantly with adducts, nor were adducts correlated with PAHs in air monitored during pregnancy. JF - Environmental Health Perspectives AU - Perera, Frederica P AU - Tang, Deliang AU - Tu, Yi-Hsuan AU - Cruz, Linda Ali AU - Borjas, Mejico AU - Bernert, Tom AU - Whyatt, Robin M Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1133 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MINORITIES KW - SUSCEPTIBILITY KW - CIGARETTE SMOKE KW - POLYCYCLIC AROMATIC HYDROCARBON KW - CARCINOGENIC AGENTS KW - REPRODUCTION, HUMAN KW - DNA KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706171?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biomarkers+in+Maternal+and+Newborn+Blood+Indicate+Heightened+Fetal+Susceptibility+to+Procarcinogenic+DNA+Damage&rft.au=Perera%2C+Frederica+P%3BTang%2C+Deliang%3BTu%2C+Yi-Hsuan%3BCruz%2C+Linda+Ali%3BBorjas%2C+Mejico%3BBernert%2C+Tom%3BWhyatt%2C+Robin+M&rft.aulast=Perera&rft.aufirst=Frederica&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1133&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MINORITIES; CARCINOGENIC AGENTS; SUSCEPTIBILITY; REPRODUCTION, HUMAN; DNA; CIGARETTE SMOKE; NEW YORK CITY; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Survivorship Patterns of Larval Amphibians Exposed to Low Concentrations of Atrazine AN - 14706108; 10665549 AB - Tadpoles of four species of frogs were exposed at early and late developmental stages to atrazine concentrations of 3, 30, or 100 ppb, and effects on survival were determined and compared. The species included: spring peepers Pseudacris crucifer, American toads Bufo americanus, green frogs Rana clamitans, and wood frogs R. sylvatica. Exposures lasted for approximately 30 d. Generally, animals exposed to the low atrazine concentration died sooner than animals exposed to the medium or high concentrations, and the pattern was similar for all species except for late American toads. JF - Environmental Health Perspectives AU - Storrs, Sara I AU - Kiesecker, Joseph M Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1054 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AGE COMPARISONS KW - TOADS KW - DOSE RESPONSE PROFILES KW - SPECIES COMPARISONS KW - ATRAZINE KW - MORTALITY PATTERNS KW - FROGS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14706108?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Survivorship+Patterns+of+Larval+Amphibians+Exposed+to+Low+Concentrations+of+Atrazine&rft.au=Storrs%2C+Sara+I%3BKiesecker%2C+Joseph+M&rft.aulast=Storrs&rft.aufirst=Sara&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1054&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 8 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; TOADS; SPECIES COMPARISONS; ATRAZINE; MORTALITY PATTERNS; AGE COMPARISONS; FROGS ER - TY - JOUR T1 - Manufactured Nanomaterials (Fullerenes, C sub(60)) Induce Oxidative Stress in the Brain of Juvenile Largemouth Bass AN - 14704212; 10665550 AB - Nanomaterials are defined as materials with at least one dimension in the 1- to 100-nm range, and fullerenes constitute one type of manufactured nanoparticle. In this study, juvenile largemouth bass Micropterus salmoides were exposed to uncoated 99.5% pure fullerenes that were water-solubilized using standard methods, and effects on oxidative stress were assessed. After 48 h of exposure to 0.5-ppm aqueous uncoated fullerenes, lipid peroxidation was elevated significantly in brains, and glutathione levels were depleted in gills. JF - Environmental Health Perspectives AU - Oberdorster, Eva Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1058 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - ANTIOXIDANTS KW - OXIDANT STRESS KW - BASS KW - GLUTATHIONE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704212?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Manufactured+Nanomaterials+%28Fullerenes%2C+C+sub%2860%29%29+Induce+Oxidative+Stress+in+the+Brain+of+Juvenile+Largemouth+Bass&rft.au=Oberdorster%2C+Eva&rft.aulast=Oberdorster&rft.aufirst=Eva&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1058&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 17 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; ANTIOXIDANTS; OXIDANT STRESS; BASS; GLUTATHIONE ER - TY - JOUR T1 - Prenatal Insecticide Exposure and Birth Weight and Length Among an Urban Minority Cohort AN - 14703731; 10665561 AB - Women who were part of an ongoing prospective cohort study of minority mothers and their newborns being conducted by the Columbia Center for Children's Environmental Health in New York City were studied to assess the relationship between prenatal insecticide exposure and birth weight and length. The effects of exposure were examined in the total cohort and again after stratifying on year of delivery. The women were enrolled between 1998 and 2002. Demographic data were obtained via questionnaire, and prenatal personal ambient-air samples were collected and analyzed. In addition, a sample of umbilical cord blood was collected, and measures of fetal growth were obtained from medical records after delivery. Results showed an inverse relationship between chlorpyrifos levels in umbilical cord plasma and birth weight and length, especially among newborns with the highest 25% of exposure levels. The data also suggested that prenatal diazinon exposure may have contributed to fetal growth deficits, and when cumulative risk assessment was conducted, the magnitude of the effect of chlorpyrifos and diazinon on birth weight was greater than that for chlorpyrifos alone. The association between insecticide exposure and fetal growth was found only when biomarkers were used as a dosimeter of prenatal exposure and not when environmental measures were used. JF - Environmental Health Perspectives AU - Whyatt, Robin M AU - Rauh, Virginia AU - Barr, Dana B AU - Camann, David E AU - Andrews, Howard F AU - Garfinkel, Robin AU - Hoepner, Lori A Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1125 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DIAZINON KW - MINORITIES KW - INSECTICIDE EXPOSURE KW - REPRODUCTION, HUMAN KW - CHLORPYRIFOS KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prenatal+Insecticide+Exposure+and+Birth+Weight+and+Length+Among+an+Urban+Minority+Cohort&rft.au=Whyatt%2C+Robin+M%3BRauh%2C+Virginia%3BBarr%2C+Dana+B%3BCamann%2C+David+E%3BAndrews%2C+Howard+F%3BGarfinkel%2C+Robin%3BHoepner%2C+Lori+A&rft.aulast=Whyatt&rft.aufirst=Robin&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1125&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DIAZINON; MINORITIES; INSECTICIDE EXPOSURE; REPRODUCTION, HUMAN; CHLORPYRIFOS; NEW YORK CITY ER - TY - JOUR T1 - Community-Based Randomized Double-Blind Study of Gastrointestinal Effects and Copper Exposure in Drinking Water AN - 14703668; 10665552 JF - Environmental Health Perspectives AU - Araya, Magdalena AU - Olivares, Manuel AU - Pizarro, Fernando AU - Llanos, Adolfo AU - Figueroa, Guillermo AU - Uauy, Ricardo Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1068 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHILE KW - DOSE RESPONSE PROFILES KW - COPPER KW - PHYSIOLOGICAL EFFECTS, HUMAN KW - WATER, DRINKING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Community-Based+Randomized+Double-Blind+Study+of+Gastrointestinal+Effects+and+Copper+Exposure+in+Drinking+Water&rft.au=Araya%2C+Magdalena%3BOlivares%2C+Manuel%3BPizarro%2C+Fernando%3BLlanos%2C+Adolfo%3BFigueroa%2C+Guillermo%3BUauy%2C+Ricardo&rft.aulast=Araya&rft.aufirst=Magdalena&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1068&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHILE; DOSE RESPONSE PROFILES; PHYSIOLOGICAL EFFECTS, HUMAN; COPPER; WATER, DRINKING ER - TY - JOUR T1 - Blood Lead Secular Trend in a Cohort of Children in Mexico City (19872002) AN - 14703485; 10665559 AB - Children in Mexico City born between 1987 and 1992 were monitored for their blood lead levels every six months for the first 10 yr of their lives. Air Pb data were collected from three monitoring stations throughout the study, and socioeconomic status was computed based on the education and occupation of the head of the household and total family income. Residence in the highest air Pb zone was associated significantly with higher lifetime blood Pb concentrations. Blood Pb levels were also associated with socioeconomic status, the age of the child at the time of Pb lead measurement, the year in which the child was born, and the family use of Pb-glazed ceramics. JF - Environmental Health Perspectives AU - Schnaas, Lourdes AU - Rothenberg, Stephen J AU - Flores, Maria-Fernanda AU - Martinez, Sandra AU - Hernandez, Carmen AU - Osorio, Erica AU - Perroni, Estela Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1110 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - SPATIAL COMPARISONS KW - AGE COMPARISONS KW - URBAN ATMOSPHERE KW - SOCIOECONOMICS KW - MEXICO KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703485?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Blood+Lead+Secular+Trend+in+a+Cohort+of+Children+in+Mexico+City+%281987%26lt%3BND%26gt%3B2002%29&rft.au=Schnaas%2C+Lourdes%3BRothenberg%2C+Stephen+J%3BFlores%2C+Maria-Fernanda%3BMartinez%2C+Sandra%3BHernandez%2C+Carmen%3BOsorio%2C+Erica%3BPerroni%2C+Estela&rft.aulast=Schnaas&rft.aufirst=Lourdes&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SOCIOECONOMICS; MEXICO; BLOOD LEAD LEVEL; SPATIAL COMPARISONS; AGE COMPARISONS; URBAN ATMOSPHERE ER - TY - JOUR T1 - Associations Between Organochlorine Contaminant Concentrations and Clinical Health Parameters in Loggerhead Sea Turtles from North Carolina, USA AN - 14703411; 10665553 AB - In 48 live, free-ranging, juvenile loggerhead sea turtles Caretta caretta collected as bycatch in Core Sound, NC, the association between indicators of health and organochlorine concentrations was explored. Almost all of the contaminants, which included chlordanes, dieldrin, mirex, DDTs, PCBs, and TCDD-like PCBs, were intercorrelated in terms of concentration. All of the major groups of contaminants were correlated with total white blood cell counts, and chlordanes and mirex were correlated significantly with fewer lymphocytes. Total DDTs and total organochlorines in both blood and adipose tissue and total PCBs in adipose tissue correlated positively with eosinophils. Body condition was correlated negative with dieldrin in blood, and glucose concentrations were correlated negatively with adipose concentrations of dieldrin and total DDTs. Blood urea nitrogen concentrations were correlated positively with concentrations of most organochlorine classes measured in blood. Aspartate aminotransferase activity was correlated positively with most of the organochlorine compounds in blood and adipose tissue, while alkaline phosphatase activity was correlated negatively with mirex concentrations in blood and adipose tissue and with TCDD-like PCBs in blood, and gamma -glutamyl transferase activity was correlated negatively with concentrations of dieldrin in blood. JF - Environmental Health Perspectives AU - Keller, Jennifer M AU - Kucklick, John R AU - Stamper, MAndrew AU - Harms, Craig A AU - McClellan-Green, Patricia D Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1074 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PESTICIDE RESIDUES KW - ENZYME ACTIVITY KW - NORTH CAROLINA KW - ORGANOCHLORINE PESTICIDES KW - BLOOD ANALYSIS KW - TURTLES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14703411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Associations+Between+Organochlorine+Contaminant+Concentrations+and+Clinical+Health+Parameters+in+Loggerhead+Sea+Turtles+from+North+Carolina%2C+USA&rft.au=Keller%2C+Jennifer+M%3BKucklick%2C+John+R%3BStamper%2C+MAndrew%3BHarms%2C+Craig+A%3BMcClellan-Green%2C+Patricia+D&rft.aulast=Keller&rft.aufirst=Jennifer&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1074&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; PESTICIDE RESIDUES; ENZYME ACTIVITY; TURTLES; NORTH CAROLINA; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Adverse Health Effects of Chronic Exposure to Low-Level Cadmium in Foodstuffs and Cigarette Smoke AN - 14702772; 10665557 AB - Clinically relevant outcomes of chronic exposure to environmental cadmium via food and cigarette smoke are highlighted, including renal failure, bone fragility, reproductive outcomes, and human cancers. Data gleaned from a number of studies conducted in different countries are cited in the discussion. Persistence of the metal in the environment and in humans will require a long-term approach to minimizing exposure, one part of which needs to be international food legislation that sets a maximum Cd level in agricultural products. JF - Environmental Health Perspectives AU - Satarug, Soisungwan AU - Moore, Michael R Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1099 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DIET KW - CADMIUM KW - BIOACCUMULATION, HUMAN KW - FOOD CONTAMINATION KW - PHYSIOLOGICAL EFFECTS, HUMAN KW - CARCINOGENIC AGENTS KW - DISEASES AND DISORDERS KW - LEGISLATION, INTERNATIONAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702772?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Adverse+Health+Effects+of+Chronic+Exposure+to+Low-Level+Cadmium+in+Foodstuffs+and+Cigarette+Smoke&rft.au=Satarug%2C+Soisungwan%3BMoore%2C+Michael+R&rft.aulast=Satarug&rft.aufirst=Soisungwan&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1099&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 54 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; CARCINOGENIC AGENTS; PHYSIOLOGICAL EFFECTS, HUMAN; LEGISLATION, INTERNATIONAL; DIET; CADMIUM; BIOACCUMULATION, HUMAN; FOOD CONTAMINATION ER - TY - JOUR T1 - Nutritional Factors and Susceptibility to Arsenic-Caused Skin Lesions in West Bengal, India AN - 14702415; 10665558 JF - Environmental Health Perspectives AU - Mitra, Soma R AU - Guha Mazumder, DN AU - Basu, Arindam AU - Block, Gladys AU - Haque, Reina AU - Samanta, Sambit AU - Ghosh, Nilima Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1104 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DEFICIENCY DISEASES KW - ARSENIC KW - NUTRITION KW - INDIA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Nutritional+Factors+and+Susceptibility+to+Arsenic-Caused+Skin+Lesions+in+West+Bengal%2C+India&rft.au=Mitra%2C+Soma+R%3BGuha+Mazumder%2C+DN%3BBasu%2C+Arindam%3BBlock%2C+Gladys%3BHaque%2C+Reina%3BSamanta%2C+Sambit%3BGhosh%2C+Nilima&rft.aulast=Mitra&rft.aufirst=Soma&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1104&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DEFICIENCY DISEASES; ARSENIC; NUTRITION; INDIA ER - TY - JOUR T1 - Association of in Utero Organophosphate Pesticide Exposure and Fetal Growth and Length of Gestation in an Agricultural Populations AN - 14702413; 10665560 AB - In an agricultural community in the Salinas Valley, CA, exposure of pregnant women to organophosphate pesticides was examined in relation to fetal growth and length of gestation. After screening, 488 pregnant women were included and were interviewed twice during pregnancy and then shortly after delivery. Exposure to organophosphate pesticides was assessed by measuring specific metabolites in maternal urine during pregnancy and by measuring chloinesterase (ChE) in whole blood and butyryl ChE in plasma of mothers during pregnancy and at delivery and in umbilical cord blood. A decrease in gestational duration was found to be associated clearly with two measures of in utero pesticide exposure: levels of metabolites of dimethyl phosphate pesticide compounds, and whole-blood ChE. No adverse relationship was found, however, between fetal growth and in utero organophosphate pesticide exposure. JF - Environmental Health Perspectives AU - Eskenazi, Brenda AU - Harley, Kim AU - Bradman, Asa AU - Weltzien, Erin AU - Jewell, Nicholas P AU - Barr, Dana B AU - Furlong, Clement E Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1116 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CHOLINESTERASE KW - CALIFORNIA KW - ORGANOPHOSPHATE PESTICIDES KW - BLOOD ANALYSIS KW - REPRODUCTION, HUMAN KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+of+in+Utero+Organophosphate+Pesticide+Exposure+and+Fetal+Growth+and+Length+of+Gestation+in+an+Agricultural+Populations&rft.au=Eskenazi%2C+Brenda%3BHarley%2C+Kim%3BBradman%2C+Asa%3BWeltzien%2C+Erin%3BJewell%2C+Nicholas+P%3BBarr%2C+Dana+B%3BFurlong%2C+Clement+E&rft.aulast=Eskenazi&rft.aufirst=Brenda&rft.date=2004-07-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=9781321249545&rft.btitle=&rft.title=Passages+and+Screens%3A+Media+Technologies+in+Texts+by+Henry+James%2C+Clara+Smith%2C+Theodora+Bosanquet%2C+Mina+Loy%2C+and+Kenneth+Fearing&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CALIFORNIA; BLOOD ANALYSIS; ORGANOPHOSPHATE PESTICIDES; REPRODUCTION, HUMAN; CHOLINESTERASE; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Personal Exposure to Submicrometer Particles and Heart Rate Variability in Human Subjects AN - 14702399; 10665551 AB - Personal exposure to submicrometer particles with a size range of 0.021.0 mu m and heart-rate variability were measured in nine young adults and ten elderly patients with lung-function impairments. Personal monitoring was performed for each subject using a P-TRAK Ultrafine Particle Counter, and continuous ambulatory electrocardiographic monitoring was conducted. The main effects of exposure to submicrometer particles were decreases in both the time-domain indices and frequency-domain indices that were consistent with effects caused by PM sub(2.5). Exposure to submicrometer particles appeared to exert similar effects on heart-rate variability in both young adults and elderly patients. The elderly panel had grater decreases in frequency-domain heart-rate variability indices in response to exposures than did the young adult panel, and only the elderly panel exhibited a time-course effect of exposure on frequency-domain heart-rate variability indices. JF - Environmental Health Perspectives AU - Chan, Chang-Chuan AU - Chuang, Kai-Jen AU - Shiao, Guang-Ming AU - Lin, Lian-Yu Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1063 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CARDIOVASCULAR EFFECTS KW - AGE COMPARISONS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702399?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Personal+Exposure+to+Submicrometer+Particles+and+Heart+Rate+Variability+in+Human+Subjects&rft.au=Chan%2C+Chang-Chuan%3BChuang%2C+Kai-Jen%3BShiao%2C+Guang-Ming%3BLin%2C+Lian-Yu&rft.aulast=Chan&rft.aufirst=Chang-Chuan&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1063&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; CARDIOVASCULAR EFFECTS; AGE COMPARISONS; PARTICULATES ER - TY - JOUR T1 - Different Levels of Polybrominated Diphenyl Ethers (PBDEs) and Chlorinated Compounds in Breast Milk from Two U.K. Regions AN - 14702363; 10665555 AB - Breast-milk samples were collected from UK women in maternity wards in London and Lancaster, and levels of polybrominated diphenyl ethers (PBDEs) were measured and related to current and temporal PCB and organochlorine levels in the country. The total PBDE levels ranged 0.169.0 ng/g lipid, and PBDE-47 was the most abundant congener. Total PCB levels ranged 26530 ng/g lipid, and congeners 153, 138, and 180 dominated. The breast-milk samples originating from London tended to exhibit higher geometric mean levels for all contaminants, including organochlorine pesticides, compared with the Lancaster levels. All relevant concentration data are tabulated. JF - Environmental Health Perspectives AU - Kalantzi, Olga I AU - Martin, Francis L AU - Thomas, Gareth O AU - Alcock, Ruth E AU - Tang, Huiru R AU - Drury, Suzanne C AU - Carmichael, Paul L Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1085 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - BREAST MILK KW - BIOACCUMULATION, HUMAN KW - ORGANOCHLORINE PESTICIDES KW - AREA COMPARISONS KW - FLAME RETARDANTS KW - UNITED KINGDOM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14702363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Different+Levels+of+Polybrominated+Diphenyl+Ethers+%28PBDEs%29+and+Chlorinated+Compounds+in+Breast+Milk+from+Two+U.K.+Regions&rft.au=Kalantzi%2C+Olga+I%3BMartin%2C+Francis+L%3BThomas%2C+Gareth+O%3BAlcock%2C+Ruth+E%3BTang%2C+Huiru+R%3BDrury%2C+Suzanne+C%3BCarmichael%2C+Paul+L&rft.aulast=Kalantzi&rft.aufirst=Olga&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1085&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AREA COMPARISONS; POLYCHLORINATED BIPHENYLS; BREAST MILK; ORGANOCHLORINE PESTICIDES; FLAME RETARDANTS; BIOACCUMULATION, HUMAN; UNITED KINGDOM ER - TY - JOUR T1 - Unhealthy Landscapes: Policy Recommendations on Land Use Change and Infectious Disease Emergence AN - 14700494; 10665556 JF - Environmental Health Perspectives AU - Patz, Jonathan A AU - Daszak, Peter AU - Tabor, Gary M AU - Aguirre, AAlonso AU - Pearl, Mary AU - Epstein, Jon AU - Wolfe, Nathan D Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1092 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DISEASES AND DISORDERS KW - PUBLIC HEALTH KW - BIOLOGICAL CONTAMINATION KW - LAND USE PLANNING KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700494?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Unhealthy+Landscapes%3A+Policy+Recommendations+on+Land+Use+Change+and+Infectious+Disease+Emergence&rft.au=Patz%2C+Jonathan+A%3BDaszak%2C+Peter%3BTabor%2C+Gary+M%3BAguirre%2C+AAlonso%3BPearl%2C+Mary%3BEpstein%2C+Jon%3BWolfe%2C+Nathan+D&rft.aulast=Patz&rft.aufirst=Jonathan&rft.date=2004-07-01&rft.volume=112&rft.issue=10&rft.spage=1092&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DISEASES AND DISORDERS; PUBLIC HEALTH; BIOLOGICAL CONTAMINATION; LAND USE PLANNING ER - TY - JOUR T1 - Associations Between Plasma DDE Levels and Immunologic Measures in African-American Farmers in North Carolina AN - 14700434; 10665554 AB - Data from a population of African-American farmers from North Carolina were used to examine the association between p,p'-DDE levels and the immunologic parameters, immunoglobulin A (IgA) and immunoglobulin G (IgG). Antinuclear antibodies were measured to assess the potential effect on autoimmunity. The study subjects consisted of male farmers or farmworkers greater than or equal to 18 yr of age with at least 2 yr of farmwork experience as an adult. An inverse association was found between levels of p,p'-DDE in blood and IgG, but no such association was found for IgA. The prevalence of antinuclear antibodies was elevated in the highest category of p,p'-DDE exposure, but the trend was not statistically significant. JF - Environmental Health Perspectives AU - Cooper, Glinda S AU - Martin, Stephen A AU - Longnecker, Matthew P AU - Sandler, Dale P AU - Germolec, Dori R Y1 - 2004/07// PY - 2004 DA - Jul 2004 SP - 1080 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 10 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AFRICAN-AMERICANS KW - DDE KW - NORTH CAROLINA KW - BIOACCUMULATION, HUMAN KW - IMMUNOTOXICITY KW - BLOOD ANALYSIS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Associations+Between+Plasma+DDE+Levels+and+Immunologic+Measures+in+African-American+Farmers+in+North+Carolina&rft.au=Haney%2C+Lindsay+J.&rft.aulast=Haney&rft.aufirst=Lindsay&rft.date=2014-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=9781339179308&rft.btitle=&rft.title=Performing+anxiety%3A+Masculinities+in+contemporary+Irish+literature+and+culture&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - IMMUNOTOXICITY; BLOOD ANALYSIS; AFRICAN-AMERICANS; DDE; NORTH CAROLINA; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Clean Air Act Issues in the 108th Congress AN - 14700737; 10666113 AB - Prominent air quality issues that have been of interest in the 108th Congress are examined. Multi-pollutant, or Clear Skies, legislation has been proposed to replace numerous existing Clean Air Act requirements with a national cap and trade program for sulfur dioxide, nitrogen oxides, and mercury. Legislation was also approved to study the New Source Review changes proposed and promulgated by EPA. Other topics covered include designation of nonattainment areas for the 8-h ozone standard, emission standards for small engines, and transportation conformity. JF - US Congressional Research Service Report IB10107 AU - McCarthy, James E Y1 - 2004/06/23/ PY - 2004 DA - 2004 Jun 23 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - SULFUR DIOXIDE KW - GASOLINE KW - TRANSPORTATION EMISSION CONTROL KW - AIR QUALITY STANDARDS, SOURCE KW - EPA, FEDERAL KW - CLEAN AIR ACT AMENDMENTS 90 KW - OZONE KW - FUEL ADDITIVES KW - POWER PLANT EMISSION CONTROL KW - MERCURY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10107&rft.atitle=Clean+Air+Act+Issues+in+the+108th+Congress&rft.au=McCarthy%2C+James+E&rft.aulast=McCarthy&rft.aufirst=James&rft.date=2004-06-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10107&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-13589.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SULFUR DIOXIDE; GASOLINE; TRANSPORTATION EMISSION CONTROL; EPA, FEDERAL; AIR QUALITY STANDARDS, SOURCE; CLEAN AIR ACT AMENDMENTS 90; POWER PLANT EMISSION CONTROL; FUEL ADDITIVES; MERCURY; OZONE ER - TY - JOUR T1 - Climate Change Legislation in the 108th Congress AN - 14701971; 10666117 AB - Bills directly addressing climate change issues in the 108th Congress range from those focused primarily on climate change research to comprehensive emissions cap and trading programs for all six greenhouse gases. Additional bills focus on greenhouse gas reporting and registries, or on power plant carbon dioxide emissions. S.139 and S.1164 would direct research on historical evidence of climate change to develop climate models; others would promote research on political and technological options to reduce emissions. Some bills would establish greenhouse gas emission thresholds above which an entity must submit records of its emissions; others exclude farms from the reporting requirement. JF - US Congressional Research Service Report RL32055 AU - Yacobucci, Brent D AU - Powers, Kyna Y1 - 2004/06/09/ PY - 2004 DA - 2004 Jun 09 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - AIR QUALITY PROGRAMS KW - LEGISLATION, FEDERAL KW - POWER PLANT EMISSIONS KW - EMISSIONS TRADING KW - CLIMATE CHANGE KW - DATA REPORTING, MANDATORY KW - GREENHOUSE EFFECT KW - CARBON DIOXIDE KW - WEATHER MODIFICATION RESEARCH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14701971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+RL32055&rft.atitle=Climate+Change+Legislation+in+the+108th+Congress&rft.au=Yacobucci%2C+Brent+D%3BPowers%2C+Kyna&rft.aulast=Yacobucci&rft.aufirst=Brent&rft.date=2004-06-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+RL32055&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-13593.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GREENHOUSE EFFECT; AIR QUALITY PROGRAMS; LEGISLATION, FEDERAL; CARBON DIOXIDE; POWER PLANT EMISSIONS; WEATHER MODIFICATION RESEARCH; EMISSIONS TRADING; CLIMATE CHANGE; DATA REPORTING, MANDATORY ER - TY - JOUR T1 - Wildfire Protection in the 108th Congress AN - 14701267; 10666115 AB - Federal wildfire management funding increased dramatically after the severe 2000 fire season. In August 2002, President Bush proposed the Health Forests Initiative, intended to improve fire protection through fuel loads reduction. Much of the focus of the 108th Congress has been on the Healthy Forests Restoration Act of 2003, which encompasses many of the issues addressed in the Healthy Forests Initiative and also includes titles allowing grants to use biomass, provides watershed forestry assistance, and establishes private forest reserves. In May 2004, federal contracts for 33 large firefighting airtankers were cancelled over concerns about their airworthiness. JF - US Congressional Research Service Report IB10124 AU - Gorte, Ross W Y1 - 2004/06/03/ PY - 2004 DA - 2004 Jun 03 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - FOREST FIRE CONTROL KW - WILDFIRES KW - FOREST MANAGEMENT KW - FOREST DEVELOPMENT FINANCING KW - LAW, FEDERAL KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14701267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10124&rft.atitle=Wildfire+Protection+in+the+108th+Congress&rft.au=Gorte%2C+Ross+W&rft.aulast=Gorte&rft.aufirst=Ross&rft.date=2004-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10124&rft.issn=&rft_id=info:doi/ L2 - http://www.csa.com/htbin/envabs.cgi?pdf=04-13591.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FOREST FIRE CONTROL; FOREST DEVELOPMENT FINANCING; FOREST MANAGEMENT; WILDFIRES; LAW, FEDERAL ER - TY - JOUR T1 - Aerodynamics, voice quality, and laryngeal image analysis of normal and pathologic voices. AN - 85391816; pmid-15167024 AB - The purpose of this review is to describe examinations of phonatory function and their relation to image analysis of the unilaterally immobile larynx. Special emphasis was placed on image analysis using three-dimensional endoscopic images produced from CT scans.Developments in modern image processing technique have led to the quantification of various aspects of vocal fold vibration. Stroboscopic images of the vocal fold were digitized and, subsequently, the glottal gap area, amplitude, and degree of bowing were analyzed quantitatively in relation to phonatory function. Vocal fold vibration was observed with the aid of videokymography, during which images from a single transverse line can be recorded. Successive line images were shown in real time on a monitor, with the time dimension displayed in the vertical direction. This system enabled the assessment of left-right asymmetries, open quotient, propagation of mucosal waves, and forth. Three-dimensional endoscopic images derived from multislice CT scans provided a novel method for evaluating morphologic characteristics of the laryngeal lumen in relation to phonatory function. The combination of three-dimensional endoscopy and coronal reconstructed images supplemented stroboscopic findings exemplified by differences in vertical position and thickness between the vocal folds.Depth information about the vocal fold as well as the presence of paradoxic movement of the affected vocal fold and overadduction of the healthy vocal fold during phonation should be taken into account when surgical intervention to improve hoarseness resulting from unilateral vocal fold immobility is performed. Phonatory function tests, videostroboscopy, and laryngeal image analysis are prerequisites to achieving this goal. JF - Current opinion in otolaryngology & head and neck surgery AU - Yumoto, Eiji AD - Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kumamoto University, Japan. yumoto@gpo.kumamoto-u.ac.jp Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 166 EP - 173 VL - 12 IS - 3 SN - 1068-9508, 1068-9508 KW - Index Medicus KW - National Library of Medicine KW - Humans KW - *Image Processing, Computer-Assisted KW - *Imaging, Three-Dimensional KW - Kymography KW - *Laryngoscopy KW - Phonation: physiology KW - Photic Stimulation KW - *Pulmonary Ventilation: physiology KW - Reference Values KW - *Tomography, X-Ray Computed KW - *User-Computer Interface KW - Video Recording KW - *Vocal Cord Paralysis: diagnosis KW - Vocal Cord Paralysis: physiopathology KW - Vocal Cords: physiopathology KW - *Voice Disorders: diagnosis KW - Voice Disorders: physiopathology KW - *Voice Quality: physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85391816?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+opinion+in+otolaryngology+%26+head+and+neck+surgery&rft.atitle=Aerodynamics%2C+voice+quality%2C+and+laryngeal+image+analysis+of+normal+and+pathologic+voices.&rft.au=Yumoto%2C+Eiji&rft.aulast=Yumoto&rft.aufirst=Eiji&rft.date=2004-06-01&rft.volume=12&rft.issue=3&rft.spage=166&rft.isbn=&rft.btitle=&rft.title=Current+opinion+in+otolaryngology+%26+head+and+neck+surgery&rft.issn=10689508&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - Expression, purification, and in vitro characterization of recombinant salmon insulin-like growth factor-II. AN - 71919334; 15135411 AB - The insulin-like growth factors, IGF-I and IGF-II, are single chain polypeptides, which are structurally related to proinsulin and promote proliferation and differentiation of cells in many vertebrate species. Previous attempts to produce recombinant salmon IGF-II (rsIGF-II) were compromised by low expression levels and co-purification of incorrectly cleaved protein with the authentic recombinant product. In this study, a gene containing the coding region for Atlantic salmon (Salmo salar) IGF-II was cloned into a modified pET32a expression vector and transformed into Escherichia coli BL21 trxB (DE3) cells. Upon growth and induction (with IPTG) of the transformant, recombinant salmon IGF-II (rsIGF-II) was expressed as an insoluble, 28kDa thioredoxin.sIGF-II fusion protein linked by a protease cleavage motif (trx.FAHY.sIGF-II) in inclusion bodies. The inclusion bodies were subsequently solubilized and the fusion protein was purified by Ni-affinity chromatography. Recombinant IGF-II (7.8kDa) was then released from the fusion partner using H64A subtilisin BPN' protease and purified by reversed-phase HPLC. Homogeneity of the final recombinant product was confirmed by N-terminal amino acid sequencing, ion-spray mass spectrometry, SDS-polyacrylamide gel electrophoresis, and analytical reversed-phase HPLC. The biological activity of rsIGF-II was demonstrated in cultured rat L6 myoblasts and was found to be approximately 9- and 5-fold less potent than recombinant human IGF-I and recombinant salmon IGF-I, respectively, a result similar to that demonstrated previously with other recombinant fish IGF-II's in non-homologous cell lines. JF - Protein expression and purification AU - Wilkinson, Ryan J AU - Elliott, Phillip AU - Carragher, John F AU - Francis, Geoffrey AD - School of Biological Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia. Ryan.Wilkinson@flinders.edu.au Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 334 EP - 343 VL - 35 IS - 2 SN - 1046-5928, 1046-5928 KW - DNA Primers KW - 0 KW - DNA, Recombinant KW - Recombinant Proteins KW - Insulin-Like Growth Factor II KW - 67763-97-7 KW - Index Medicus KW - Salmon KW - Animals KW - Electrophoresis, Polyacrylamide Gel KW - Fermentation KW - Escherichia coli -- genetics KW - Amino Acid Sequence KW - Recombinant Proteins -- genetics KW - Chromatography, High Pressure Liquid KW - Mutagenesis, Site-Directed KW - Recombinant Proteins -- isolation & purification KW - Base Sequence KW - Molecular Sequence Data KW - Insulin-Like Growth Factor II -- genetics KW - Insulin-Like Growth Factor II -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71919334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Protein+expression+and+purification&rft.atitle=Expression%2C+purification%2C+and+in+vitro+characterization+of+recombinant+salmon+insulin-like+growth+factor-II.&rft.au=Wilkinson%2C+Ryan+J%3BElliott%2C+Phillip%3BCarragher%2C+John+F%3BFrancis%2C+Geoffrey&rft.aulast=Wilkinson&rft.aufirst=Ryan&rft.date=2004-06-01&rft.volume=35&rft.issue=2&rft.spage=334&rft.isbn=&rft.btitle=&rft.title=Protein+expression+and+purification&rft.issn=10465928&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-03-29 N1 - Date created - 2004-05-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - RPRT T1 - How CBO Analyzes the Sources of Lenders' Interest Income on Guaranteed Student Loans. A CBO Report AN - 62013739; ED496555 AB - The Federal Family Education Loan (FFEL) program guarantees loans for postsecondary education to students and their parents at a limited interest rate. However, limiting borrowers' rates creates a danger that lenders will not be willing to participate in the program if their costs of financing and servicing the loans exceed the interest rates they may charge borrowers. To avoid that situation, the government generally supplements the borrowers' interest payments with additional quarterly payments to meet a target interest rate (or lender yield), which is an indicator of lenders' costs. The amounts that lenders receive from borrowers and the government depend on formulas specified in law and on the current level of two market interest rates, one used to calculate what borrowers pay and the other used to calculate the target yield for lenders, which determines what the government pays. This report describes the method the Congressional Budget Office (CBO) uses to estimate the sources of lenders' interest income on student and parent loans in the Federal Family Education Loan program. That method accounts for the likely values of future interest rates and specific program rules, including those for setting borrowers' rates and for calculating the government's supplemental payments. Includes the following appendix: Federal Student Loan Programs. (Contains 3 tables and 7 footnotes.) AU - Alsalam, Nabeel Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 20 PB - Congressional Budget Office. Ford House Office Building, 4th Floor, Second and D Streets SW, Washington, DC 20515-6925. KW - Family Education Loan program KW - ERIC, Resources in Education (RIE) KW - Postsecondary Education KW - Credit (Finance) KW - Federal Aid KW - Student Loan Programs KW - Government Role KW - Debt (Financial) KW - Income KW - Student Financial Aid KW - Costs KW - Computation KW - Federal Legislation KW - Public Agencies KW - Federal Programs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62013739?accountid=14244 LA - English DB - ERIC N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - The Post-Apartheid Economy AN - 60713830; 200502554 AB - South Africa's postapartheid economy has been characterized by low growth & investment, & a rise in unemployment (at 30%, higher than any other middle income country). Government economic policy has stressed the encouragement of investment through deregulation, privatization, & fiscal restraint. However, the failure of this strategy to promote growth & create jobs points to the need for a more interventionist strategy, one in which government must do more to stimulate equitable growth. This proposition is highly contested. Nonetheless, in response to the crisis within the economy, the government has adopted limited reforms involving increased spending on basic social services & housing, greater emphasis on job creation & equity, a renewed stress on planning & coordination & greater support for cooperatives. Yet these new initiatives do not constitute a systematic plan for transforming the economy & more integrated policies are required to overcome dualism & stimulate job-creating growth. 11 Tables, 25 References. Adapted from the source document. JF - Review of African Political Economy AU - Makgetla, Neva Seidman AD - Congress South African Trade Unions neva@cosatu.org.za Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 263 EP - 281 VL - 31 IS - 100 SN - 0305-6244, 0305-6244 KW - State Intervention KW - Economic Conditions KW - Economic Development KW - Development Strategies KW - South Africa KW - Investment KW - Economic Policy KW - article KW - 9141: political economy; political economy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60713830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Review+of+African+Political+Economy&rft.atitle=The+Post-Apartheid+Economy&rft.au=Makgetla%2C+Neva+Seidman&rft.aulast=Makgetla&rft.aufirst=Neva&rft.date=2004-06-01&rft.volume=31&rft.issue=100&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=Review+of+African+Political+Economy&rft.issn=03056244&rft_id=info:doi/10.1080%2F0305624042000262284 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 29 N1 - Last updated - 2016-09-28 N1 - CODEN - RAPEF9 N1 - SubjectsTermNotLitGenreText - South Africa; Economic Conditions; Economic Development; Investment; State Intervention; Development Strategies; Economic Policy DO - http://dx.doi.org/10.1080/0305624042000262284 ER - TY - JOUR T1 - The Law: Must the Senate Take a Floor Vote on a Presidential Judicial Nominee? AN - 60699927; 200417121 AB - President George W. Bush has frequently urged the Senate to fulfill its constitutional duty & vote on his nominations to the federal courts. The administration argues that the Senate must hold up-or-down floor votes on all judicial nominees. Senate Democrats counter that the president is trying to short-circuit the procedural steps of the confirmation process. Currently, both sides are waging an ideological & institutional battle over the judicial confirmation process. This article analyzes the claim that the Senate must vote on all of the president's judicial nominees, & concludes that there is no basis for requiring that the Senate must hold mandatory confirmation votes for lower-court nominees. By tradition, the Senate generally takes floor votes for nominations to the Supreme Court. 36 References. Adapted from the source document. JF - Presidential Studies Quarterly AU - Sollenberger, Mitchel A AD - Congressional Research Service Y1 - 2004/06// PY - 2004 DA - June 2004 SP - 420 EP - 436 VL - 34 IS - 2 SN - 0360-4918, 0360-4918 KW - nominations KW - Presidents KW - Roll Call KW - United States of America KW - Voting Behavior KW - Legislative Bodies KW - Judges KW - article KW - 9161: politics and law; politics and law UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60699927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Presidential+Studies+Quarterly&rft.atitle=The+Law%3A+Must+the+Senate+Take+a+Floor+Vote+on+a+Presidential+Judicial+Nominee%3F&rft.au=Sollenberger%2C+Mitchel+A&rft.aulast=Sollenberger&rft.aufirst=Mitchel&rft.date=2004-06-01&rft.volume=34&rft.issue=2&rft.spage=420&rft.isbn=&rft.btitle=&rft.title=Presidential+Studies+Quarterly&rft.issn=03604918&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Number of references - 36 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Legislative Bodies; Presidents; Judges; Voting Behavior; Roll Call; United States of America ER - TY - JOUR T1 - Environmental Index for Assessing Spatial Bias in Watershed Sampling Networks AN - 20604207; 6157005 AB - Bias in the design of stream-sampling networks can be a major cause of inaccurate characterization of ambient water quality. At the state level, sampling bias can impact a state's ability to produce an accurate assessment of the water quality of all state waters. At the federal level, this bias has hindered attempts by the U.S. Environmental Protection Agency (U.S. EPA) to produce nationwide assessments of water quality. Three types of bias commonly occur in water-quality assessments: design, analytical, and statistical. This paper focuses on "design bias," especially spatial-design bias, in stream monitoring networks. A geographic information system method is described to develop an environmental index to help recognize spatial design bias, and to prioritize areas (subwatersheds) for sampling. The environmental index, which is developed using data that are generally available from federal and state agencies, provides a means of differentiating the component parts of a watershed, its subwatersheds, in terms of two sets of features: natural landscape features and anthropogenic features or "stressors." Together, these features largely determine the variability of the quantity and quality of water discharged from watersheds. Subwatersheds with higher environmental-index values are expected to have more variable water quality over the course of a year than subwatersheds with lower index values. They are also expected to exert a greater influence on basinwide water quality. These properties of the index make it useful for (1) identifying the possible presence of spatial bias in existing watershed-sampling networks, (2) making sampling design decisions, and (3) aggregating data from subwatersheds into basinwide measures of water quality. Development and use of the index is demonstrated in a watershed in southern New Hampshire. JF - Journal of Environmental Engineering AU - Simcox, A C AU - Whittemore, R C AD - U.S. EPA Region 1 TMDL Coordinator, U.S. EPA, 1 Congress St., Ste. 1100 (CWQ), Boston, MA 02114, USA Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 622 EP - 630 VL - 130 IS - 6 SN - 0733-9372, 0733-9372 KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Water Resources Abstracts KW - water quality KW - Pollution monitoring KW - Variability KW - Remote sensing KW - Anthropogenic factors KW - Water quality KW - Watersheds KW - Streams KW - Assessments KW - Networks KW - Sampling KW - USA, New Hampshire KW - Geographical Information Systems KW - Environmental assessment KW - Landscape KW - Water Quality KW - Environmental Protection KW - Environmental protection KW - EPA KW - Geographic information systems KW - Monitoring KW - P 2000:FRESHWATER POLLUTION KW - SW 3010:Identification of pollutants KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - Q5 08522:Protective measures and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20604207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Engineering&rft.atitle=Environmental+Index+for+Assessing+Spatial+Bias+in+Watershed+Sampling+Networks&rft.au=Simcox%2C+A+C%3BWhittemore%2C+R+C&rft.aulast=Simcox&rft.aufirst=A&rft.date=2004-06-01&rft.volume=130&rft.issue=6&rft.spage=622&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Engineering&rft.issn=07339372&rft_id=info:doi/10.1061%2F%28ASCE%290733-9372%282004%29130%3A6%28622%29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-08-01 N1 - SuppNotes - Special Issue: Quantitative Approaches to the Determination of Total Maximum Daily Loads. N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Pollution monitoring; Environmental assessment; Anthropogenic factors; Sampling; Watersheds; Water quality; Environmental protection; EPA; water quality; Landscape; Remote sensing; Geographic information systems; Streams; Variability; Assessments; Networks; Water Quality; Environmental Protection; Monitoring; Geographical Information Systems; USA, New Hampshire DO - http://dx.doi.org/10.1061/(ASCE)0733-9372(2004)130:6(622) ER - TY - JOUR T1 - Preparation, properties, and mathematical modeling of microparticle drug delivery systems based on biodegradable amphiphilic triblock copolymers AN - 19477928; 8216829 AB - A series of biodegradable amphiphilic A-B-A type triblock copolymers P(BLA-PEG-BLA), composed of hydrophilic poly(ethylene glycol) (PEG) as a middle block component (B) and hydrophobic poly(-benzyl-L-aspartate) as outer polypeptide block components (A), were synthesized by copolymerization of -benzyl-L-aspartate N-carboxy anhydride (BLA-NCA) and the diaminated PEG with the primary amino groups capped at both ends. These P(BLA-PEG-BLA) copolymers were characterized by 1H-NMR, DSC, and GPC. The triblock copolymers were used to prepare three kinds of drug delivery systems including Norfloxacin (INN)-incorporated P(BLA-PEG-BLA) microparticles and tablets. The morphologies of the microparticles were characterized by SEM. The in vitro release properties of the microparticles and tablets in PBS were also evaluated. A mathematical model, which incorporates a linear first-order dissolution term and the transient Fickian diffusion equation, was developed to account for the kinetics of drug release from the INN-incorporated P(BLA-PEG-BLA) microparticles. The results indicated that the overall release process was well controlled by both drug dissolution and diffusion. JF - Journal of Applied Polymer Science AU - Yan, Guo-Ping AU - Li, Hua AU - Cheng, Si-Xue AU - Bottle, Steven E AU - Wang, Xiao-Gui AU - Yew, Yong Kin AU - Zhuo, Ren-Xi AD - School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Q4001, Australia, guopyan@hotmail.com Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 3869 EP - 3873 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk], [URL:http://www.wiley.com/] VL - 92 IS - 6 SN - 0021-8995, 0021-8995 KW - Biotechnology and Bioengineering Abstracts KW - Drug delivery KW - Norfloxacin KW - Amino groups KW - Mathematical models KW - microparticles KW - Tablets KW - Hydrophobicity KW - Kinetics KW - Copolymers KW - Dissolution KW - Diffusion KW - Polyethylene glycol KW - W 30915:Pharmaceuticals & Vaccines UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19477928?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Polymer+Science&rft.atitle=Preparation%2C+properties%2C+and+mathematical+modeling+of+microparticle+drug+delivery+systems+based+on+biodegradable+amphiphilic+triblock+copolymers&rft.au=Yan%2C+Guo-Ping%3BLi%2C+Hua%3BCheng%2C+Si-Xue%3BBottle%2C+Steven+E%3BWang%2C+Xiao-Gui%3BYew%2C+Yong+Kin%3BZhuo%2C+Ren-Xi&rft.aulast=Yan&rft.aufirst=Guo-Ping&rft.date=2004-06-01&rft.volume=92&rft.issue=6&rft.spage=3869&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Polymer+Science&rft.issn=00218995&rft_id=info:doi/10.1002%2Fapp.20410 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-01-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Drug delivery; Amino groups; Norfloxacin; Mathematical models; microparticles; Kinetics; Tablets; Copolymers; Dissolution; Hydrophobicity; Diffusion; Polyethylene glycol DO - http://dx.doi.org/10.1002/app.20410 ER - TY - JOUR T1 - Monoterpenes and Epicuticular Waxes Help Female Autumn Gum Moth Differentiate Between Waxy and Glossy Eucalyptus and Leaves of Different Ages AN - 18065231; 6023312 AB - The autumn gum moth, Mnesampela privata, is a native Australian species whose preferred host, Eucalyptus globulus (Myrtaceae), is an aromatic evergreen tree that has long-lived waxy leaves during the juvenile phase of growth. We compared the behavioral and antennal responses of female moths to whole leaves (new and old) and samples of foliar chemicals (from new and old leaves) from a typical E. globulus subsp. pseudoglobulus with responses to a glossy, half-sibling E. g. subsp. pseudoglobulus putative hybrid (the result of natural cross-pollination). We also studied larval survival and development on leaves from the same trees. In laboratory binary-choice assays, female M. privata laid more eggs on waxy leaves than on glossy leaves thereby confirming the nonpreference for the glossy tree that was observed in the field. Analyses of the monoterpenes and waxes of both trees revealed that they had comparable suites of monoterpenes and total oil contents but different suites of epicuticular waxes. Headspace extracts differed in the intensity of component monoterpenes. Gas chromatographic analyses with electroantennographic detection showed different patterns of monoterpene detection. Leaves of the glossy tree had a less diverse array of epicuticular waxes than those of the waxy tree. Electroantennographic screening of responses to wax extracts from leaves (new and old) from either tree revealed positive dose-dependent responses of female antennae to waxes from new leaves only. Binary-choice assays also revealed a strong preference by ovipositing females for new, compared to old, leaves whether they were from the waxy or the glossy tree. However, new leaves from either tree could be manipulated (by physical abrasion of epicuticular waxes) so that females would lay almost no eggs on them. Larval survival did not differ between groups reared on leaves from both trees (new and old). Over 70% of all larvae survived to pupation. However, larvae reared on leaves from the glossy tree took longer to pupate than those reared on leaves from the waxy tree. Also, larvae reared on new leaves from either tree did not perform as well as those reared on old leaves. Monoterpene and wax cues are suggested as helping female M. privata locate preferred hosts in native forests. JF - Journal of Chemical Ecology AU - Steinbauer, MJ AU - Schiestl, F P AU - Davies, N W AD - CRC for Sustainable Production Forestry and CSIRO Entomology, G.P.O. Box 1700, Canberra, A.C.T. 2601, Australia, martin.steinbauer@csiro.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1117 EP - 1142 PB - Kluwer Academic Publishers VL - 30 IS - 6 SN - 0098-0331, 0098-0331 KW - Bluegum eucalyptus KW - Autumn gum moth KW - Myrtles KW - Chemoreception Abstracts; Animal Behavior Abstracts; Entomology Abstracts; Ecology Abstracts KW - Fitness KW - Leaf characters KW - Myrtaceae KW - Monoterpenes KW - Waxes KW - Eucalyptus globulus KW - Mnesampela privata KW - Host preferences KW - Defense mechanisms KW - Oviposition KW - Z 05203:Relations to plants KW - D 04659:Insects KW - Y 25503:Insects KW - R 18051:Reproductive behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18065231?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Chemical+Ecology&rft.atitle=Monoterpenes+and+Epicuticular+Waxes+Help+Female+Autumn+Gum+Moth+Differentiate+Between+Waxy+and+Glossy+Eucalyptus+and+Leaves+of+Different+Ages&rft.au=Steinbauer%2C+MJ%3BSchiestl%2C+F+P%3BDavies%2C+N+W&rft.aulast=Steinbauer&rft.aufirst=MJ&rft.date=2004-06-01&rft.volume=30&rft.issue=6&rft.spage=1117&rft.isbn=&rft.btitle=&rft.title=Journal+of+Chemical+Ecology&rft.issn=00980331&rft_id=info:doi/10.1023%2FB%3AJOEC.0000030267.75347.c1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eucalyptus globulus; Mnesampela privata; Myrtaceae; Host preferences; Fitness; Oviposition; Defense mechanisms; Leaf characters; Waxes; Monoterpenes DO - http://dx.doi.org/10.1023/B:JOEC.0000030267.75347.c1 ER - TY - JOUR T1 - Reliability of EMG measurements for trunk muscles during maximal and sub-maximal voluntary isometric contractions in healthy controls and CLBP patients AN - 17932360; 5886208 AB - The purpose of this study was to compare the reliability of trunk muscle activity measured by means of surface electromyography (EMG) during maximal and sub-maximal voluntary isometric contractions (MVC/sub-MVC) over repeated trials within-day and between-days in healthy controls and patients with chronic low back pain (CLBP). Eleven volunteers (six controls and five CLBP patients) were assessed twice with a 1-week interval. Surface EMG signals were recorded bilaterally from six trunk muscles. Intra-class correlation coefficients (ICC) and standard error of measurement as a percentage of the grand mean (%SEM) were calculated. MVC and sub-MVC showed excellent within-day reliability in both healthy controls and CLBP patients (ICC mean 0.91; range 0.75-0.98; %SEM mean 4%; range 1-12%). Sub-MVC for both groups between-days showed excellent reliability (ICC mean 0.88; range 0.78-0.97; %SEM mean 7%; range 3-11%). The between-days MVC for both groups showed trends towards lower levels of reliability (ICC mean 0.70; range 0.19-0.99; %SEM mean 17%; range 4-36%) when compared to sub-MVC. Findings of the study provide evidence that sub-MVC are preferable for amplitude normalisation when assessing EMG signals of trunk muscles between-days. JF - Journal of Electromyography and Kinesiology AU - Dankaerts, W AU - O'Sullivan, P B AU - Burnett, A F AU - Straker, L M AU - Danneels, LA AD - School of Physiotherapy, Bld 408, Curtin University of Technology, GPO Box U1987, Perth, 6845, WA, Australia, dankaerw@ses.curtin.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 333 EP - 342 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 14 IS - 3 SN - 1050-6411, 1050-6411 KW - Physical Education Index KW - Trunk KW - Electromyography KW - Isometrics KW - Muscles (contractions) KW - PE 100:Kinesiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17932360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Electromyography+and+Kinesiology&rft.atitle=Reliability+of+EMG+measurements+for+trunk+muscles+during+maximal+and+sub-maximal+voluntary+isometric+contractions+in+healthy+controls+and+CLBP+patients&rft.au=Dankaerts%2C+W%3BO%27Sullivan%2C+P+B%3BBurnett%2C+A+F%3BStraker%2C+L+M%3BDanneels%2C+LA&rft.aulast=Dankaerts&rft.aufirst=W&rft.date=2004-06-01&rft.volume=14&rft.issue=3&rft.spage=333&rft.isbn=&rft.btitle=&rft.title=Journal+of+Electromyography+and+Kinesiology&rft.issn=10506411&rft_id=info:doi/10.1016%2Fj.jelekin.2003.07.001 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Electromyography; Isometrics; Muscles (contractions); Trunk DO - http://dx.doi.org/10.1016/j.jelekin.2003.07.001 ER - TY - JOUR T1 - Identifying hazards in complex ecological systems. Part 3: Hierarchical Holographic Model for herbicide tolerant oilseed rape AN - 17880595; 6101303 AB - This paper is the third in a series designed to demonstrate the application of rigorous, systematic hazard identification techniques to ecological systems. Here we use Hierarchical Holographic Modelling to identify the potential ecological hazards associated with the commercial release of herbicide tolerant oilseed rape. Hierarchical Holographic Models decompose complex systems into a series of sub-systems and consider interactions between the components and processes of these sub-systems in order to identify hazards. In this example we considered 1356 potential interactions between the biological, chemical and physical components and processes of the herbicide tolerant oilseed rape environment, and identified 152 potential hazards, grouped into 14 categories. The hazards were subsequently scored for degree of concern and plausibility, and then compared with an equivalent list of hazards generated independently by a checklist approach. The incidence of herbicide tolerant volunteers (and weeds) both on and off the farm had the highest average score of all the ecological hazard categories. The checklist based approach identified or implied 44% of the hazards identified in the Hierarchical Holographic Model, including nine of the ten hazards ranked most important. The checklist approach focussed almost exclusively on the phenotypic and genotypic hazards associated with herbicide tolerant oilseed rape and largely ignored the hazards associated with the circumstances surrounding its use. As a result the checklist identified only 6 out of the 79 potential hazards associated with changes to farming practice. The commercial release of herbicide tolerant oilseed rape will be associated with changes in tillage and the application of post-emergent herbicides. It may also lead to changes in spray schedules of insecticide and fungicide. Many of the environmental hazards identified with these changes are plausible and may warrant further investigation or targeted monitoring. JF - Environmental Biosafety Research AU - Hayes, K R AU - Gregg, P C AU - Gupta, VVSR AU - Jessop, R AU - Lonsdale, WM AU - Sindel, B AU - Stanley, J AU - Williams, C K AD - CSIRO Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, keith.hayes@csiro.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 109 EP - 128 VL - 3 IS - 2 SN - 1635-7922, 1635-7922 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Weeds KW - Insecticides KW - Farms KW - Mathematical models KW - Tillage KW - Fungicides KW - Check lists KW - Herbicides KW - W 30965:Miscellaneous, Reviews KW - W4 310:Agricultural Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17880595?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Biosafety+Research&rft.atitle=Identifying+hazards+in+complex+ecological+systems.+Part+3%3A+Hierarchical+Holographic+Model+for+herbicide+tolerant+oilseed+rape&rft.au=Hayes%2C+K+R%3BGregg%2C+P+C%3BGupta%2C+VVSR%3BJessop%2C+R%3BLonsdale%2C+WM%3BSindel%2C+B%3BStanley%2C+J%3BWilliams%2C+C+K&rft.aulast=Hayes&rft.aufirst=K&rft.date=2004-06-01&rft.volume=3&rft.issue=2&rft.spage=109&rft.isbn=&rft.btitle=&rft.title=Environmental+Biosafety+Research&rft.issn=16357922&rft_id=info:doi/10.1051%2Febr%3A2004012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Herbicides; Check lists; Mathematical models; Fungicides; Farms; Insecticides; Weeds; Tillage DO - http://dx.doi.org/10.1051/ebr:2004012 ER - TY - JOUR T1 - Comparison between closed-loop portal and peripheral venous insulin delivery systems for an artificial endocrine pancreas AN - 17585830; 6001372 AB - To establish the ideal insulin delivery route for an artificial endocrine pancreas, we examined the effectiveness of closed-loop portal insulin delivery. We investigated the effects of the route of insulin delivery on net hepatic glucose balance (NHGB) in dogs under pancreatic clamp conditions with somatostatin plus basal glucagon and insulin infusions. A constant rate of suprabasal insulin was infused via the portal vein or a peripheral vein, and glucose was infused into the portal vein for 180 min. The mean net hepatic glucose uptake (NHGU) values in the portal insulin infusion group (PI group) were significantly greater than those in the peripheral venous insulin infusion group (VI group); the changes from the baseline values at 180 min were 3.54 plus or minus 0.66 and 2.45 plus or minus 0.82 mg kg super(-1) min super(-1) in the PI and VI groups, respectively, P < 0.05. Furthermore, dogs under pancreatic clamp conditions were controlled after a 2-g/kg oral glucose load by applying the closed-loop intraportal (PO) or intravenous (IV) insulin infusion algorithm. There were no significant differences in glycemic control and insulin requirements between these algorithms. However, the maximum peripheral venous and arterial plasma insulin concentrations with the PO algorithm were significantly lower than those with the IV algorithm [305.1 plus or minus 68.9 and 468.1 plus or minus 66.9 pmol/l (peripheral vein) and 305.3 plus or minus 62.9 and 469.6 plus or minus 85.1 pmol/l (artery) with the PO and IV algorithms, respectively, P < 0.05]. On the other hand, the maximum portal plasma insulin concentration with the PO algorithm was significantly higher than that with the IV algorithm (619.9 plus or minus 101.7 and 414.3 plus or minus 79.9 pmol/l with the PO and IV algorithms, respectively, P < 0.05). The mean NHGU values with the PO algorithm were significantly greater than those with the IV algorithm. Our results confirmed that closed-loop portal insulin delivery is feasible with regard to both insulin profiles and hepatic glucose handling in vivo, and indicated that the portal vein is the most suitable insulin delivery route for the artificial endocrine pancreas. JF - Journal of Artificial Organs AU - Sekigami, Taiji AU - Shimoda, Seiya AU - Nishida, Kenro AU - Matsuo, Yasuto AU - Ichimori, Shinji AU - Ichinose, Kenshi AU - Shichiri, Motoaki AU - Sakakida, Michiharu AU - Araki, Eiichi AD - Department of Metabolic Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan, sshimoda@gpo.kumamoto-u.ac.jp Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 91 EP - 100 VL - 7 IS - 2 SN - 1434-7229, 1434-7229 KW - Biotechnology and Bioengineering Abstracts; Bioengineering Abstracts KW - Drug delivery KW - Arteries KW - Glucagon KW - Pancreas KW - Glucose KW - Algorithms KW - Portal vein KW - Somatostatin KW - Insulin KW - Veins KW - Liver KW - artificial organs KW - W 30965:Miscellaneous, Reviews KW - W4 110:Biomedical Materials & Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17585830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Artificial+Organs&rft.atitle=Comparison+between+closed-loop+portal+and+peripheral+venous+insulin+delivery+systems+for+an+artificial+endocrine+pancreas&rft.au=Sekigami%2C+Taiji%3BShimoda%2C+Seiya%3BNishida%2C+Kenro%3BMatsuo%2C+Yasuto%3BIchimori%2C+Shinji%3BIchinose%2C+Kenshi%3BShichiri%2C+Motoaki%3BSakakida%2C+Michiharu%3BAraki%2C+Eiichi&rft.aulast=Sekigami&rft.aufirst=Taiji&rft.date=2004-06-01&rft.volume=7&rft.issue=2&rft.spage=91&rft.isbn=&rft.btitle=&rft.title=Journal+of+Artificial+Organs&rft.issn=14347229&rft_id=info:doi/10.1007%2Fs10047-004-0251-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Insulin; Algorithms; Glucose; Pancreas; Liver; Portal vein; Veins; artificial organs; Drug delivery; Somatostatin; Glucagon; Arteries DO - http://dx.doi.org/10.1007/s10047-004-0251-2 ER - TY - JOUR T1 - A randomized trial of interactive group sessions achieved greater improvements in nutrition and physical activity at a tiny increase in cost AN - 17582896; 6001345 AB - Weight gain may follow altered eating habits and decreased physical activity in couples beginning to live together. Mutual support and willingness to accept changes in lifestyle at this stage may facilitate positive responses to health promotion. We aimed to compare the effects of a diet and physical activity program in couples using a randomized controlled trial. Couples were randomized to a control group or to one of two intervention groups in whom the program was either delivered mainly by mail or with a combination of mail-outs and interactive group sessions. Diets, physical fitness, and blood cholesterol improved up to 12 months after beginning the 4-month program, mainly in the interactive group. In that group, at the end of the program, the estimated cost was $445.30 ($111.33/month) per participant per unit change in outcome variables, only $0.03 per participant per month more than the group receiving the program mainly by mail. One year after beginning the program, costs per participant per month were $38.37 in the interactive group and $38.22 in the group receiving the program mainly by mail-out. The changes observed in cardiovascular risk factors could translate to a substantial cost-savings relating to health. JF - Journal of Clinical Epidemiology AU - Dzator, JA AU - Hendrie, D AU - Burke, V AU - Gianguilio, N AU - Gillam, H F AU - Beilin, L J AU - Houghton, S AD - School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit and West Australian Institute for Medical Research, Box X2213 GPO, Perth 6847, Western Australia, vburke@cyllene.uwa.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 610 EP - 619 VL - 57 IS - 6 SN - 0895-4356, 0895-4356 KW - Physical Education Index KW - Diet (effects) KW - Programs KW - Promotion KW - Lipids KW - Diet (weight control) KW - Intervention KW - Health KW - Exercise KW - Nutrition KW - Exercise (programs) KW - Lifestyle KW - Blood KW - Social support KW - Risk factors KW - Physical fitness KW - Economics KW - Cardiorespiratory KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17582896?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Epidemiology&rft.atitle=A+randomized+trial+of+interactive+group+sessions+achieved+greater+improvements+in+nutrition+and+physical+activity+at+a+tiny+increase+in+cost&rft.au=Dzator%2C+JA%3BHendrie%2C+D%3BBurke%2C+V%3BGianguilio%2C+N%3BGillam%2C+H+F%3BBeilin%2C+L+J%3BHoughton%2C+S&rft.aulast=Dzator&rft.aufirst=JA&rft.date=2004-06-01&rft.volume=57&rft.issue=6&rft.spage=610&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Epidemiology&rft.issn=08954356&rft_id=info:doi/10.1016%2Fj.jclinepi.2003.10.009 LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Programs; Exercise; Economics; Social support; Diet (effects); Health; Cardiorespiratory; Lipids; Blood; Promotion; Intervention; Lifestyle; Risk factors; Physical fitness; Exercise (programs); Nutrition; Diet (weight control) DO - http://dx.doi.org/10.1016/j.jclinepi.2003.10.009 ER - TY - JOUR T1 - Identification and Characterization of the Novel LysM Domain-Containing Surface Protein Sep from Lactobacillus fermentum BR11 and Its Use as a Peptide Fusion Partner in Lactobacillus and Lactococcus AN - 17352780; 6406775 AB - Examination of supernatant fractions from broth cultures of Lactobacillus fermentum BR11 revealed the presence of a number of proteins, including a 27-kDa protein termed Sep. The amino-terminal sequence of Sep was determined, and the gene encoding it was cloned and sequenced. Sep is a 205-amino-acid protein and contains a 30-amino-acid secretion signal and has overall homology (between 39 and 92% identity) with similarly sized proteins of Lactobacillus reuteri, Enterococcus faecium, Streptococcus pneumoniae, Streptococcus agalactiae, and Lactobacillus plantarum. The carboxy-terminal 81 amino acids of Sep also have strong homology (86% identity) to the carboxy termini of the aggregation-promoting factor (APF) surface proteins of Lactobacillus gasseri and Lactobacillus johnsonii. The mature amino terminus of Sep contains a putative peptidoglycan-binding LysM domain, thereby making it distinct from APF proteins. We have identified a common motif within LysM domains that is shared with carbohydrate binding YG motifs which are found in streptococcal glucan-binding proteins and glucosyltransferases. Sep was investigated as a heterologous peptide expression vector in L. fermentum, Lactobacillus rhamnosus GG and Lactococcus lactis MG1363. Modified Sep containing an amino-terminal six-histidine epitope was found associated with the cells but was largely present in the supernatant in the L. fermentum, L. rhamnosus, and L. lactis hosts. Sep as well as the previously described surface protein BspA were used to express and secrete in L. fermentum or L. rhamnosus a fragment of human E-cadherin, which contains the receptor region for Listeria monocytogenes. This study demonstrates that Sep has potential for heterologous protein expression and export in lactic acid bacteria. JF - Applied and Environmental Microbiology AU - Turner AU - Hafner, L M AU - Walsh, T AU - Giffard, P M AD - Infectious Diseases Program, School of Life Sciences, Faculty of Science, Queensland University of Technology, G.P.O. Box 2434, Brisbane, Queensland 4001, Australia, ms.turner@qut.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 3673 EP - 3680 VL - 70 IS - 6 SN - 0099-2240, 0099-2240 KW - Biotechnology and Bioengineering Abstracts; Agricultural and Environmental Biotechnology Abstracts; Microbiology Abstracts B: Bacteriology KW - W2 32340:Other peptides, proteins, amino acids KW - W 30965:Miscellaneous, Reviews KW - J 02727:Amino acids, peptides and proteins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17352780?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Identification+and+Characterization+of+the+Novel+LysM+Domain-Containing+Surface+Protein+Sep+from+Lactobacillus+fermentum+BR11+and+Its+Use+as+a+Peptide+Fusion+Partner+in+Lactobacillus+and+Lactococcus&rft.au=Turner%3BHafner%2C+L+M%3BWalsh%2C+T%3BGiffard%2C+P+M&rft.aulast=Turner&rft.aufirst=&rft.date=2004-06-01&rft.volume=70&rft.issue=6&rft.spage=3673&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.70.6.3673-3680.2004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-01-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1128/AEM.70.6.3673-3680.2004 ER - TY - JOUR T1 - Measurement and prediction of energy expenditure in males during household and garden tasks AN - 17255248; 6988947 JF - European Journal of Applied Physiology AU - Gunn, S M AU - van der Ploeg, GE AU - Withers, R T AU - Gore, C J AU - Owen, N AU - Bauman, A E AU - Cormack, J AD - Exercise Physiology Laboratory, School of Education, Flinders University, GPO Box 2100, Adelaide, South Australia, Australia 5001, bob.withers@flinders.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 231 VL - 92 IS - 1-2 SN - 1439-6319, 1439-6319 KW - Physical Education Index KW - Energy cost KW - Measurement KW - Men KW - Activities KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17255248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Applied+Physiology&rft.atitle=Measurement+and+prediction+of+energy+expenditure+in+males+during+household+and+garden+tasks&rft.au=Gunn%2C+S+M%3Bvan+der+Ploeg%2C+GE%3BWithers%2C+R+T%3BGore%2C+C+J%3BOwen%2C+N%3BBauman%2C+A+E%3BCormack%2C+J&rft.aulast=Gunn&rft.aufirst=S&rft.date=2004-06-01&rft.volume=92&rft.issue=1-2&rft.spage=231&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Applied+Physiology&rft.issn=14396319&rft_id=info:doi/10.1007%2Fs00421-004-1100-y LA - English DB - Physical Education Index N1 - Date revised - 2006-08-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Measurement; Activities; Men; Energy cost DO - http://dx.doi.org/10.1007/s00421-004-1100-y ER - TY - JOUR T1 - Vacuum ultraviolet irradiation for natural organic matter removal AN - 16174011; 5997434 AB - Low pressure mercury vapour lamps were used alone and in combination with hydrogen peroxide (H sub(2)O sub(2)) to investigate the removal of natural organic matter (NOM) from highly coloured surface water, high in total organic carbon (TOC). A potential benefit of vacuum ultraviolet (VUV) irradiation is additive-free degradation of NOM by hydroxyl radicals rather than concentration and subsequent disposal problems associated with many conventional techniques. For mineralization and chromophore removal the UV/VUV/H sub(2)O sub(2) combination was most effective, followed by UV/VUV. Photooxidation alone was inappropriate because small (but much greater than normal UV disinfection doses) and intermediate doses increased chlorine demand, trihalomethane formation potential, nitrite, hydrogen peroxide and low molecular weight carbonyl compound concentrations. Subsequent biological treatment reduced the chlorine reactivity significantly, by removal of oxidized NOM intermediates. Low molecular weight carbonyl compound concentrations in the water increased significantly on irradiation, and differences in their speciation indicated that different reaction mechanisms were dominant in different treatments. Trihalomethane (THM) distribution shifted to more highly brominated compounds as the NOM concentration decreased with treatment. Results from this preliminary study indicate that NOM can be removed from water by VUV irradiation combined with biological treatment leading to improved drinking water quality. JF - Aqua - Journal of Water Supply: Research and Technology AU - Thomson, J AU - Roddick, F A AU - Drikas, M AD - School of Civil and Chemical Engineering, RMIT University, GPO Box 2476V, Melbourne, Victoria 3001, Australia, felicity.roddick@rmit.edu.au Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 193 EP - 206 VL - 53 IS - 4 SN - 0003-7214, 0003-7214 KW - Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Disinfection KW - Speciation KW - Degradation KW - Hydrogen Peroxide KW - Surface water KW - Water Supply KW - Surface Water KW - Drinking Water KW - Organic Matter KW - Water treatment KW - Distribution KW - Ultraviolet radiation KW - Water Treatment KW - Hydroxyl Radical KW - Organic Carbon KW - Organic matter KW - Hydroxyl radicals KW - Nitrites KW - Trihalomethanes KW - Irradiation KW - Mercury KW - Chlorination KW - Drinking water KW - Biological Treatment KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - AQ 00004:Water Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16174011?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aqua+-+Journal+of+Water+Supply%3A+Research+and+Technology&rft.atitle=Vacuum+ultraviolet+irradiation+for+natural+organic+matter+removal&rft.au=Thomson%2C+J%3BRoddick%2C+F+A%3BDrikas%2C+M&rft.aulast=Thomson&rft.aufirst=J&rft.date=2004-06-01&rft.volume=53&rft.issue=4&rft.spage=193&rft.isbn=&rft.btitle=&rft.title=Aqua+-+Journal+of+Water+Supply%3A+Research+and+Technology&rft.issn=00037214&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-01-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Water treatment; Nitrites; Surface water; Irradiation; Trihalomethanes; Organic matter; Ultraviolet radiation; Chlorination; Drinking water; Hydroxyl radicals; Hydroxyl Radical; Speciation; Disinfection; Degradation; Hydrogen Peroxide; Organic Carbon; Water Supply; Surface Water; Drinking Water; Organic Matter; Distribution; Water Treatment; Mercury; Biological Treatment ER - TY - JOUR T1 - Endangered Species: Difficult Choices AN - 14718682; 10673303 AB - Different proposals to amend the 1973 Endangered Species Act (ESA) are being considered by the 108th Congress. Major issues of debate concern specific regional resource conflicts, use of sound science, critical habitat designation, private property and takings, and rendering the ESA more user-friendly. Legislation was submitted to provide FY2004 USDI appropriations of $265 million for programs related to endangered species, and to direct that critical habitat not be designated on military lands under certain conditions when Integrated Natural Resources Management Plans are in effect. Additional statutes directed that a healthy forests reserve program be established to promote recovery of threatened and endangered species. JF - US Congressional Research Service Report IB10072 AU - Corn, MLynne AU - Buck, Eugene H AU - Baldwin, Pamela Y1 - 2004/06// PY - 2004 DA - Jun 2004 PB - US Congressional Research Service, The Boulevard Kidlington Oxford OX5 1GB KW - Environment Abstracts KW - ENDANGERED SPECIES ACT 73 KW - LEGISLATION, FEDERAL KW - FOREST MANAGEMENT KW - LAND MANAGEMENT KW - ENV RESTORATION KW - WILDLIFE MANAGEMENT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14718682?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=US+Congressional+Research+Service+Report+IB10072&rft.atitle=Endangered+Species%3A+Difficult+Choices&rft.au=Corn%2C+MLynne%3BBuck%2C+Eugene+H%3BBaldwin%2C+Pamela&rft.aulast=Corn&rft.aufirst=MLynne&rft.date=2004-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=US+Congressional+Research+Service+Report+IB10072&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ENV RESTORATION; LEGISLATION, FEDERAL; ENDANGERED SPECIES ACT 73; FOREST MANAGEMENT; WILDLIFE MANAGEMENT; LAND MANAGEMENT ER - TY - JOUR T1 - Spatial Analysis of the Relationship Between Mortality from Cardiovascular and Cerebrovascular Disease and Drinking Water Hardness AN - 14701157; 10663802 AB - The Spanish Rapid Inquiry Facility (RIF), which is an analytical tool for quick assessment that is applied to data gathered in the information system developed within the European Health and Environment Information System, was used to examine spatially the relationship between mortality from cardiovascular and cerebrovascular disease and drinking-water hardness in all municipalities of Comunidad Valenciana. Exposure analysis with RIF was performed by defining regions composed to geographical units sharing similar levels of the risk factor. A statistical analysis was performed using the estimation of the relative risk in each region by the corresponding standardized mortality ratio of observed to expected mortality counts. Results suggested a relationship between calcium and magnesium in water and the data on mortality from cerebrovascular and ischemic diseases. The relationship was stronger for cerebrovascular disease in women. JF - Environmental Health Perspectives AU - Ferrandiz, Juan AU - Abellan, Juan J AU - Gomez-Rubio, Virgilio AU - Lopez-Quilez, Antonio AU - Sanmartin, Pilar AU - Abellan, Carlos AU - Martinez-Beneito, Miguel A Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1037 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SPAIN KW - SPATIAL COMPARISONS KW - RISK ASSESSMENT KW - GEOGRAPHIC INFORMATION SYSTEMS KW - WATER HARDNESS KW - MORTALITY PATTERNS KW - CARDIOVASCULAR DISORDERS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14701157?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Spatial+Analysis+of+the+Relationship+Between+Mortality+from+Cardiovascular+and+Cerebrovascular+Disease+and+Drinking+Water+Hardness&rft.au=Ferrandiz%2C+Juan%3BAbellan%2C+Juan+J%3BGomez-Rubio%2C+Virgilio%3BLopez-Quilez%2C+Antonio%3BSanmartin%2C+Pilar%3BAbellan%2C+Carlos%3BMartinez-Beneito%2C+Miguel+A&rft.aulast=Ferrandiz&rft.aufirst=Juan&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1037&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 19 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; SPAIN; GEOGRAPHIC INFORMATION SYSTEMS; WATER HARDNESS; MORTALITY PATTERNS; SPATIAL COMPARISONS; CARDIOVASCULAR DISORDERS ER - TY - JOUR T1 - Cancer Risk near a Polluted River in Finland AN - 14700183; 10663800 AB - Cancer risk was investigated in people living near the River Kymijoki, Finland, using the small-area statistics on health system designed for investigations of cancer risk near geographically defined exposure sources. Due to past contamination, the river sediments contain high levels of PCDDs and PCDFs. The study population was defined as all people living within 20 km from the river, and the study area was divided into nine sub-areas according to increasing distance to the river downstream from a factory producing the chlorophenol fungicide, Ky-5. Risk was assessed for total cancer and for 27 selected cancer types for all people, and separately for farmers, living near the river since the end of December 1980. Cancer incidence in all people, as well as in farmers, living close to the river was at the level expected based on national rates, For all people living less than 1 km from the river, however, the socioeconomic status-adjusted relative risks for total cancer were consistently greater than 1, and the relative risks for farmers were generally higher than the relative risks for all residents. JF - Environmental Health Perspectives AU - Verkasalo, Pia K AU - Kokki, Esa AU - Pukkala, Eero AU - Vartiainen, Terttu AU - Kiviranta, Hannu AU - Penttinen, Antti AU - Pekkanen, Juha Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1026 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - POLYCHLORINATED DIBENZODIOXINS KW - SPATIAL COMPARISONS KW - POLYCHLORINATED DIBENZOFURANS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - FINLAND KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700183?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Cancer+Risk+near+a+Polluted+River+in+Finland&rft.au=Verkasalo%2C+Pia+K%3BKokki%2C+Esa%3BPukkala%2C+Eero%3BVartiainen%2C+Terttu%3BKiviranta%2C+Hannu%3BPenttinen%2C+Antti%3BPekkanen%2C+Juha&rft.aulast=Verkasalo&rft.aufirst=Pia&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1026&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t maps N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; GEOGRAPHIC INFORMATION SYSTEMS; POLYCHLORINATED DIBENZODIOXINS; SPATIAL COMPARISONS; FINLAND; POLYCHLORINATED DIBENZOFURANS ER - TY - JOUR T1 - Using Geographic Information Systems for Exposure Assessment in Environmental Epidemiology Studies AN - 14700154; 10663798 AB - The use of geographic information systems (GISs) in spatial statistics for linking exposure and health data in the context of epidemiologic analysis is a growing field of research. The fundamentals of the scientific disciplines required to use a GIS in such studies are discussed, focusing on four important areas: defining the study population, identifying source and potential routes of exposure, estimating environmental levels of target contaminants, and estimating personal exposures. Information obtained from the scientific literature suggest that a GIS can enhance epidemiologic research greatly in terms of the definition of source and routes of potential exposure and the estimation of environmental levels of target contaminants in the exposure assessment process. JF - Environmental Health Perspectives AU - Nuckols, John R AU - Ward, Mary H AU - Jarup, Lars Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1007 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - GEOGRAPHIC INFORMATION SYSTEMS KW - PUBLIC HEALTH KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+Geographic+Information+Systems+for+Exposure+Assessment+in+Environmental+Epidemiology+Studies&rft.au=Nuckols%2C+John+R%3BWard%2C+Mary+H%3BJarup%2C+Lars&rft.aulast=Nuckols&rft.aufirst=John&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1007&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - GEOGRAPHIC INFORMATION SYSTEMS; PUBLIC HEALTH ER - TY - JOUR T1 - Rationale for a New Generation of Indicators for Coastal Waters AN - 14700072; 10663794 AB - Four critical areas are identified in which scientific advancements are needed before improvements can be made in indicator development of coastal regions. The areas, each of which is discussed, include: linking stress with response, multiple stressors of environmental condition, spatial and temporal explicitness, and reference conditions. Two brief examples are presented of new types of indicators, one that links productivity and hydrology and another than links community patterns. Analyses of photopigments can provide a means to explicitly link nutrient and hydrologic stressors with specific phytoplanton groups, while multitaxa types of approaches can provide a wide range of possibilities for improving the knowledge of stress-response relationships, the identification of multiple stressor effects, spatial and temporal explicitness, and the identification of suitable reference conditions. JF - Environmental Health Perspectives AU - Niemi, Gerald AU - Wardrop, Denice AU - Brooks, Robert AU - Anderson, Susan AU - Brady, Valerie AU - Paerl, Hans AU - Rakocinski, Chet Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 979 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - COASTAL WATERS KW - ESTUARIES KW - BIOLOGICAL INDICATORS, MARINE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14700072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Rationale+for+a+New+Generation+of+Indicators+for+Coastal+Waters&rft.au=Niemi%2C+Gerald%3BWardrop%2C+Denice%3BBrooks%2C+Robert%3BAnderson%2C+Susan%3BBrady%2C+Valerie%3BPaerl%2C+Hans%3BRakocinski%2C+Chet&rft.aulast=Niemi&rft.aufirst=Gerald&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=979&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; COASTAL WATERS; ESTUARIES; BIOLOGICAL INDICATORS, MARINE ER - TY - JOUR T1 - Use of GIS and Exposure Modeling as Tools in a Study of Cancer Incidence in a Population Exposed to Airborne Dioxin AN - 14699661; 10663801 JF - Environmental Health Perspectives AU - Poulstrup, A AU - Hansen, H L Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 1032 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DENMARK KW - MATHEMATIC MODELS, AIR KW - CANCER RISK KW - AIR POLLUTION EFFECTS KW - GEOGRAPHIC INFORMATION SYSTEMS KW - DIOXINS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699661?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Use+of+GIS+and+Exposure+Modeling+as+Tools+in+a+Study+of+Cancer+Incidence+in+a+Population+Exposed+to+Airborne+Dioxin&rft.au=Poulstrup%2C+A%3BHansen%2C+H+L&rft.aulast=Poulstrup&rft.aufirst=A&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=1032&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MATHEMATIC MODELS, AIR; DENMARK; CANCER RISK; AIR POLLUTION EFFECTS; GEOGRAPHIC INFORMATION SYSTEMS; DIOXINS ER - TY - JOUR T1 - Pesticide Testing in Humans: Ethics and Public Policy AN - 14699511; 10663565 AB - An expert workshop was convened in February 2002 by the Center for Children's Health and the Environment of the Mount Sinai School of Medicine to discuss the ethics of pesticide testing in humans. The history of such testing in the US is reviewed, and the ethical issues are highlighted. Several recommendations agreed upon by the participants are proposed that address the need to establish ethical guidelines for US EPA studies and ethical constraints on research. JF - Environmental Health Perspectives AU - Oleskey, Christopher AU - Fleischman, Alan AU - Goldman, Lynn AU - Hirschhorn, Kurt AU - Landrigan, Philip J AU - Lappe, Marc AU - Marshall, Mary Faith Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 914 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ENV ETHICS KW - MEASUREMENTS AND SENSING KW - DOSE RESPONSE PROFILES KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Pesticide+Testing+in+Humans%3A+Ethics+and+Public+Policy&rft.au=Oleskey%2C+Christopher%3BFleischman%2C+Alan%3BGoldman%2C+Lynn%3BHirschhorn%2C+Kurt%3BLandrigan%2C+Philip+J%3BLappe%2C+Marc%3BMarshall%2C+Mary+Faith&rft.aulast=Oleskey&rft.aufirst=Christopher&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=914&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 40 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; ENV ETHICS; DOSE RESPONSE PROFILES; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Sample Characterization of Automobile and Forklift Diesel Exhaust Particles and Comparative Pulmonary Toxicity in Mice AN - 14699490; 10663550 AB - Mice were exposed by involuntary aspiration to 0, 25, or 100 mu g of automobile diesel exhaust particles (DEPs) or forklift DEPs, the latter being the National Institute of Standards Technology standard reference material, and pulmonary inflammation and lung injury were evaluated in bronchoalveolar lavage fluid at 4 and 18 h after exposure. Animals were also exposed to a dose of an organic extract of the DEPs equivalent to the proportional mass of the fraction present in a 100- mu g dose of the particle sample. Results showed that the two DEP samples differed in size, texture, and color. The two DEPs produced similar levels of acute pulmonary injury and interleukin-6, but induced distinctly different cellular inflammatory responses. The forklift DEPs caused an increase in polymorphonuclear cells, while the automobile DEPs caused an increase in macrophages, which suggested divergent mechanisms of cellular recruitment and activation. For both DEP samples, the increases in bronchoalveolar lavage fluid polymorphonuclear cells or macrophages were dose-dependent. JF - Environmental Health Perspectives AU - Singh, Pramila AU - DeMarini, David M AU - Dick, Colin AJ AU - Tabor, Dennis G AU - Ryan, Jeff V AU - Linak, William P AU - Kobayashi, Takahiro Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 820 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSE RESPONSE PROFILES KW - DIESEL ENGINES, TRANSPORT KW - AUTOMOBILE EMISSIONS KW - PULMONARY EFFECTS KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699490?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Sample+Characterization+of+Automobile+and+Forklift+Diesel+Exhaust+Particles+and+Comparative+Pulmonary+Toxicity+in+Mice&rft.au=Singh%2C+Pramila%3BDeMarini%2C+David+M%3BDick%2C+Colin+AJ%3BTabor%2C+Dennis+G%3BRyan%2C+Jeff+V%3BLinak%2C+William+P%3BKobayashi%2C+Takahiro&rft.aulast=Singh&rft.aufirst=Pramila&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=820&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 9 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSE RESPONSE PROFILES; DIESEL ENGINES, TRANSPORT; AUTOMOBILE EMISSIONS; PULMONARY EFFECTS; PARTICULATES ER - TY - JOUR T1 - Estradiol Uptake, Toxicity, Metabolism, and Adverse Effects on Cadmium-Treated Amphibian Embryos AN - 14699419; 10663556 AB - The toxicity of 17 beta -estradiol, its uptake and metabolism, and the effect of 17 beta -estradiol on cadmium toxicity were examined in embryos of the South American toad Bufo arenarum. The LC sub(50) values for 17 beta -estradiol at 48 and 96 h of exposure decreased from 33.69 to 15.13 mu mol/l. Uptake of 17 beta -estradiol at 0.5, 1.0, 2.0, 4.0, and 8.0 h was 13.52, 17.15, 19.17, 19.38, and 20.10 ng/mg, respectively. At low 17 beta -estradiol exposure concentrations, Cd toxicity was enhanced within the first 24 h of exposure, and the tendency was maintained until the third day of exposure. By day seven, however, no differences were observed between the embryos treated with Cd plus 17 beta -estradiol and those treated with Cd alone. JF - Environmental Health Perspectives AU - Fridman, Osvaldo AU - Corro, Lucrecia AU - Herkovits, Jorge Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 862 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOACCUMULATION, ANIMAL KW - CADMIUM KW - HORMONES KW - TOADS KW - DOSE RESPONSE PROFILES KW - METABOLIC ACTIVATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Estradiol+Uptake%2C+Toxicity%2C+Metabolism%2C+and+Adverse+Effects+on+Cadmium-Treated+Amphibian+Embryos&rft.au=Fridman%2C+Osvaldo%3BCorro%2C+Lucrecia%3BHerkovits%2C+Jorge&rft.aulast=Fridman&rft.aufirst=Osvaldo&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=862&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOACCUMULATION, ANIMAL; DOSE RESPONSE PROFILES; TOADS; METABOLIC ACTIVATION; CADMIUM; HORMONES ER - TY - JOUR T1 - Adipose Tissue Levels of Organochlorine Pesticides and Polychlorinated Biphenyls and Risk of Non-Hodgkin's Lymphoma AN - 14699384; 10663555 AB - Data from an EPA study of organochlorine pesticide and PCB exposure in the general population, which involved examination of adipose tissue from postmortem and surgical specimens, were used to examine the association between the risk of non-Hodgkin's lymphoma (NHL) and adipose organochlorine pesticide and PCB levels using a case-control study design. The cases were those in the data set who had a diagnosis of NHL, and controls were selected from subjects with a diagnosis of accidental injury or death and no cancer diagnosis, and from subjects with a diagnosis of myocardial infarction and no cancer diagnosis. The controls were matched on age, sex, geographic region, and race. For all adipose residues, the mean was higher in cases than in controls, and levels were significantly higher for dieldrin, oxychlordane, heptachlor epoxide, and hexachlorobenzene. The DDT-related residue, p,p'-DDE, was significantly increased among cases in the highest quartile. The levels of beta -benzene hexachloride and dieldrin were associated significantly with NHL risk among cases in the highest exposure quartiles, but there were no significant associations of hexachlorobenzene or PCBs with NHL risk. Higher levels of oxychlordane and heptachlor epoxide were associated significantly with the odds of NHL. JF - Environmental Health Perspectives AU - Quintana, Penelope JE AU - Delfino, Ralph J AU - Korrick, Susan AU - Ziogas, Argyrios AU - Kutz, Frederick W AU - Jones, Ellen L AU - Laden, Francine Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 854 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - POLYCHLORINATED BIPHENYLS KW - ORGANOCHLORINE PESTICIDES KW - BIOACCUMULATION, HUMAN KW - DISEASES AND DISORDERS KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699384?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Adipose+Tissue+Levels+of+Organochlorine+Pesticides+and+Polychlorinated+Biphenyls+and+Risk+of+Non-Hodgkin%27s+Lymphoma&rft.au=Quintana%2C+Penelope+JE%3BDelfino%2C+Ralph+J%3BKorrick%2C+Susan%3BZiogas%2C+Argyrios%3BKutz%2C+Frederick+W%3BJones%2C+Ellen+L%3BLaden%2C+Francine&rft.aulast=Quintana&rft.aufirst=Penelope&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=854&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; POLYCHLORINATED BIPHENYLS; DISEASES AND DISORDERS; PESTICIDE EXPOSURE; BIOACCUMULATION, HUMAN; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Prediction of Residential Pet and Cockroach Allergen Levels Using Questionnaire Information AN - 14699365; 10663552 AB - Interviews were conducted in the homes of 932 newborns in Connecticut and Massachusetts to ascertain cat and dog ownership and the presence of cockroaches. Dust samples were collected during the home interviews and analyzed for the presence of major cat, dog, and German cockroach allergens using two-site monoclonal antibody-based enzyme-linked immunosorbent assays. The aim was to examine how accurately questionnaire-reported data predicted measured allergen levels. Results revealed that specificity was high for all three allergens, whereas sensitivity was low, particularly for current pet ownership and cat and dog allergens above the limit of detection and the lower cut point. Questionnaire-reported presence of cats was a relatively poor measure of cat allergen levels in house dust, whereas cockroach allergen in house dust was related strongly to the reported presence of cockroaches in the home. JF - Environmental Health Perspectives AU - Gehring, Ulrike AU - Triche, Elizabeth AU - van Strien, Robert T AU - Belanger, Kathleen AU - Holford, Theodore AU - Gold, Diane R AU - Jankun, Thomas Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 834 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOMESTIC ANIMALS KW - ALLERGIES KW - COCKROACHES KW - SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Prediction+of+Residential+Pet+and+Cockroach+Allergen+Levels+Using+Questionnaire+Information&rft.au=Gehring%2C+Ulrike%3BTriche%2C+Elizabeth%3Bvan+Strien%2C+Robert+T%3BBelanger%2C+Kathleen%3BHolford%2C+Theodore%3BGold%2C+Diane+R%3BJankun%2C+Thomas&rft.aulast=Gehring&rft.aufirst=Ulrike&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=834&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 10 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOMESTIC ANIMALS; ALLERGIES; COCKROACHES; SURVEYS ER - TY - JOUR T1 - Lung Cancer Risk After Exposure to Polycyclic Aromatic Hydrocarbons: a Review and Meta-Analysis AN - 14698998; 10663793 JF - Environmental Health Perspectives AU - Armstrong, Ben AU - Hutchinson, Emma AU - Unwin, John AU - Fletcher, Tony Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 970 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - DOSE RESPONSE PROFILES KW - BENZO-A-PYRENE KW - POLYCYCLIC AROMATIC HYDROCARBON KW - LITERATURE SURVEYS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14698998?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Lung+Cancer+Risk+After+Exposure+to+Polycyclic+Aromatic+Hydrocarbons%3A+a+Review+and+Meta-Analysis&rft.au=Armstrong%2C+Ben%3BHutchinson%2C+Emma%3BUnwin%2C+John%3BFletcher%2C+Tony&rft.aulast=Armstrong&rft.aufirst=Ben&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=970&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; DOSE RESPONSE PROFILES; BENZO-A-PYRENE; LITERATURE SURVEYS; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Recent Developments in Low-Level Lead Exposure and Intellectual Impairment in Children AN - 14698708; 10663795 AB - There is considerable uncertainty about the effects of low levels of lead exposure on children's health. Here, a review is presented of the issue, citing data from the literature on the sources of Pb exposure and current blood Pb levels. Eight recent cross-sectional studies are identified that have looked at the relationship between Pb concentrations and children's cognitive abilities. The evidence for lowered intellectual and cognitive ability in children exposed to Pb comes largely from prospective epidemiologic studies of cohorts in a number of cities in the US, Australia, and Yugoslavia. The findings support an association between childhood Pb exposure and subsequent cognitive impairment and extend the range of concern to children with lifetime average blood Pb levels 1 10 super(-6 )for daily consumption of greater than or equal to 17 g of soft-shell clam meat. JF - Environmental Health Perspectives AU - Gagnon, Fabien AU - Tremblay, Thierry AU - Rouette, Justine AU - Cartier, Jacques-Francois Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 883 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - FOOD CONSUMPTION PATTERNS KW - CANCER RISK KW - POLYCHLORINATED BIPHENYLS KW - FOOD CONTAMINATION KW - SHELLFISH KW - ARSENIC KW - CLAMS KW - ST LAWRENCE RIVER KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695960?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Chemical+Risks+Associated+with+Consumption+of+Shellfish+Harvested+on+the+North+Shore+of+the+St.+Lawrence+River%27s+Lower+Estuary&rft.au=Gagnon%2C+Fabien%3BTremblay%2C+Thierry%3BRouette%2C+Justine%3BCartier%2C+Jacques-Francois&rft.aulast=Gagnon&rft.aufirst=Fabien&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=883&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 7 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FOOD CONSUMPTION PATTERNS; SHELLFISH; CANCER RISK; POLYCHLORINATED BIPHENYLS; ARSENIC; CLAMS; ST LAWRENCE RIVER; FOOD CONTAMINATION ER - TY - JOUR T1 - Health and Environment Information Systems for Exposure and Disease Mapping, and Risk Assessment AN - 14695829; 10663796 AB - While overlaying maps of exposure and populations can define populations at risk, such linking is highly dependent on the accuracy of exposure assessment and the time elapsed between initial exposure and disease. The use of geographic information systems for exposure and disease mapping and risk assessment is outlined briefly. The main advantage of such an approach is the possibility of modeling exposure geographically so that individual exposure may be estimated without the need for time-consuming and extensive measurements. Two such systems, the UK Small Area Health Statistics Unit and the European Health and Environment Information System, are described. JF - Environmental Health Perspectives AU - Jarup, Lars Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 995 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 9 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - RISK ASSESSMENT KW - INFORMATION SYSTEMS, ENV KW - GEOGRAPHIC INFORMATION SYSTEMS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695829?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Health+and+Environment+Information+Systems+for+Exposure+and+Disease+Mapping%2C+and+Risk+Assessment&rft.au=Jarup%2C+Lars&rft.aulast=Jarup&rft.aufirst=Lars&rft.date=2004-06-01&rft.volume=112&rft.issue=9&rft.spage=995&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 29 |t References N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; INFORMATION SYSTEMS, ENV; GEOGRAPHIC INFORMATION SYSTEMS ER - TY - JOUR T1 - Ultrafine Particle Deposition in Subjects with Asthma AN - 14695311; 10663559 AB - Sixteen men and women with mild asthma were exposed to ultrafine carbon particles for 2 h via mouthpiece, and deposition was measured during spontaneous breathing at rest and with exercise. Results revealed that the number deposition fraction increased as particle size decreased, and deposition increased with exercise. A significant correlation was observed between tidal volume and deposition fraction. The total number of particles retained in the lung was 74% greater in subjects with asthma than in healthy subjects. JF - Environmental Health Perspectives AU - Chalupa, David C AU - Morrow, Paul E AU - Oberdorster, Gunter AU - Utell, Mark J AU - Frampton, Mark W Y1 - 2004/06// PY - 2004 DA - Jun 2004 SP - 879 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 8 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - ASTHMA KW - PARTICULATES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695311?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Ultrafine+Particle+Deposition+in+Subjects+with+Asthma&rft.au=Chalupa%2C+David+C%3BMorrow%2C+Paul+E%3BOberdorster%2C+Gunter%3BUtell%2C+Mark+J%3BFrampton%2C+Mark+W&rft.aulast=Chalupa&rft.aufirst=David&rft.date=2004-06-01&rft.volume=112&rft.issue=8&rft.spage=879&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - AIR POLLUTION EFFECTS; ASTHMA; PARTICULATES ER - TY - JOUR T1 - Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. AN - 71900411; 14993220 AB - Ca2+-regulated exocytosis of lysosomes has been recognized recently as a ubiquitous process, important for the repair of plasma membrane wounds. Lysosomal exocytosis is regulated by synaptotagmin VII, a member of the synaptotagmin family of Ca2+-binding proteins localized on lysosomes. Here we show that Ca2+-dependent interaction of the synaptotagmin VII C(2)A domain with SNAP-23 is facilitated by syntaxin 4. Specific interactions also occurred in cell lysates between the plasma membrane t-SNAREs SNAP-23 and syntaxin 4 and the lysosomal v-SNARE TI-VAMP/VAMP7. Following cytosolic Ca2+ elevation, SDS-resistant complexes containing SNAP-23, syntaxin 4, and TI-VAMP/VAMP7 were detected on membrane fractions. Lysosomal exocytosis was inhibited by the SNARE domains of syntaxin 4 and TI-VAMP/VAMP7 and by cleavage of SNAP-23 with botulinum neurotoxin E, thereby functionally implicating these SNAREs in Ca2+-regulated exocytosis of conventional lysosomes. JF - The Journal of biological chemistry AU - Rao, Swathi K AU - Huynh, Chau AU - Proux-Gillardeaux, Veronique AU - Galli, Thierry AU - Andrews, Norma W AD - Section of Microbial Pathogenesis and Department of Cell Biology, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06511, USA. Y1 - 2004/05/07/ PY - 2004 DA - 2004 May 07 SP - 20471 EP - 20479 VL - 279 IS - 19 SN - 0021-9258, 0021-9258 KW - Antigens, CD KW - 0 KW - Bacterial Proteins KW - Calcium-Binding Proteins KW - Carrier Proteins KW - Lysosome-Associated Membrane Glycoproteins KW - Membrane Glycoproteins KW - Membrane Proteins KW - Nerve Tissue Proteins KW - Protein Isoforms KW - Qa-SNARE Proteins KW - Qb-SNARE Proteins KW - Qc-SNARE Proteins KW - R-SNARE Proteins KW - Recombinant Proteins KW - SNAP23 protein, human KW - SNARE Proteins KW - Streptolysins KW - Sybl1 protein, rat KW - Syt7 protein, rat KW - Vesicular Transport Proteins KW - streptolysin O KW - Synaptotagmins KW - 134193-27-4 KW - DNA KW - 9007-49-2 KW - beta-N-Acetylhexosaminidases KW - EC 3.2.1.52 KW - Calcium KW - SY7Q814VUP KW - Index Medicus KW - Animals KW - Electroporation KW - Calcium -- chemistry KW - Streptolysins -- pharmacology KW - Cell Survival KW - Calcium -- metabolism KW - Microscopy, Fluorescence KW - Rats KW - DNA -- chemistry KW - Flow Cytometry KW - Recombinant Proteins -- chemistry KW - Carrier Proteins -- metabolism KW - Dose-Response Relationship, Drug KW - beta-N-Acetylhexosaminidases -- chemistry KW - Precipitin Tests KW - Protein Binding KW - Antigens, CD -- metabolism KW - Cell Membrane -- metabolism KW - Protein Structure, Tertiary KW - Nerve Tissue Proteins -- physiology KW - Membrane Glycoproteins -- physiology KW - Membrane Proteins -- metabolism KW - Exocytosis KW - Nerve Tissue Proteins -- metabolism KW - Lysosomes -- metabolism KW - Membrane Glycoproteins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71900411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+biological+chemistry&rft.atitle=Identification+of+SNAREs+involved+in+synaptotagmin+VII-regulated+lysosomal+exocytosis.&rft.au=Rao%2C+Swathi+K%3BHuynh%2C+Chau%3BProux-Gillardeaux%2C+Veronique%3BGalli%2C+Thierry%3BAndrews%2C+Norma+W&rft.aulast=Rao&rft.aufirst=Swathi&rft.date=2004-05-07&rft.volume=279&rft.issue=19&rft.spage=20471&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+biological+chemistry&rft.issn=00219258&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-15 N1 - Date created - 2004-05-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The evidence for the safety of thiomersal in newborn and infant vaccines. AN - 71892510; 15121295 AB - While a number of studies remain to be completed, evidence is mounting that there is no demonstrable risk for infants immunized with vaccines containing thiomersal. Epidemiological studies in the US have shown no developmental or other central nervous system abnormalities resulting from exposure to vaccines containing thiomersal. During the initial evaluation of thiomersal in vaccines during 1999, the toxicological profile of ethyl mercury was unknown and presumed to be the same as that of methyl mercury. Enough evidence has accumulated since then to indicate the profiles of the two compounds are different in crucial aspects. To date, one study has measured blood levels of total mercury in vaccinated infants and reports only a brief low-level exposure with rapid excretion of mercury. It is not yet known for sure how much (if any) vaccine-derived ethyl mercury in the blood crosses the blood-brain barrier. For the most part, the use of thiomersal as a vaccine preservative has been convincingly shown to be safe. The scientific evidence is not yet sufficiently strong to provide the same level of assurance for thiomersal-containing vaccines for use in pregnant women or the premature or low birth weight infant. There is an increased sensitivity of the fetal brain to mercury whether it is ethyl or methyl mercury. While there is no evidence to support the contention, it is at least theoretically possible that very low birth weight premature infants may be at increased risk from thiomersal-containing vaccines. Until such time as the scientific evidence is to hand, thiomersal-free presentations of hepatitis B are to be preferred for the birth dose. Given the same levels of exposure, adults are at much lower levels of risk because of increased body mass. It is not possible to prove that thiomersal is completely safe-epidemiology can only quantify a risk, not prove its absence. JF - Vaccine AU - Clements, C John AD - Centre for International Health, The Macfarlane Burnet Institute for Medical Research and Public Health Ltd, GPO Box 2284, Commercial Road, Melbourne, Vic. 3004, Australia. john@clem.com.au Y1 - 2004/05/07/ PY - 2004 DA - 2004 May 07 SP - 1854 EP - 1861 VL - 22 IS - 15-16 SN - 0264-410X, 0264-410X KW - Ethylmercury Compounds KW - 0 KW - Methylmercury Compounds KW - Preservatives, Pharmaceutical KW - Vaccines KW - Thimerosal KW - 2225PI3MOV KW - Index Medicus KW - Infant, Very Low Birth Weight KW - Infant KW - Animals KW - Humans KW - Fishes KW - Adult KW - Infant, Newborn KW - Ethylmercury Compounds -- toxicity KW - Infant, Premature KW - Methylmercury Compounds -- toxicity KW - Female KW - Pregnancy KW - Vaccines -- adverse effects KW - Thimerosal -- adverse effects KW - Thimerosal -- toxicity KW - Preservatives, Pharmaceutical -- toxicity KW - Preservatives, Pharmaceutical -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71892510?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=The+evidence+for+the+safety+of+thiomersal+in+newborn+and+infant+vaccines.&rft.au=Clements%2C+C+John&rft.aulast=Clements&rft.aufirst=C&rft.date=2004-05-07&rft.volume=22&rft.issue=15-16&rft.spage=1854&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-18 N1 - Date created - 2004-05-03 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Vaccine. 2004 Dec 2;23(3):281-2 [15530668] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Do preserved foods increase prostate cancer risk? AN - 66652786; 15208621 AB - Preserved foods have been found in some studies to be associated with increased cancer risks. The possible relationship between preserved foods and prostate cancer was investigated in a case-control study in southeast China during 2001-2002 covering 130 histologically confirmed cases and 274 inpatient controls without malignant disease. The total amount of preserved food consumed was positively associated with cancer risk, the adjusted odds ratio being 7.05 (95% CI: 3.12-15.90) for the highest relative to the lowest quartile of intake. In particular, the consumption of pickled vegetables, fermented soy products, salted fish and preserved meats was associated with a significant increase in prostate cancer risk, all with a significant dose-response relationship. JF - British journal of cancer AU - Jian, L AU - Zhang, D H AU - Lee, A H AU - Binns, C W AD - School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia. Y1 - 2004/05/04/ PY - 2004 DA - 2004 May 04 SP - 1792 EP - 1795 VL - 90 IS - 9 SN - 0007-0920, 0007-0920 KW - Food Preservatives KW - 0 KW - Index Medicus KW - Risk Factors KW - Humans KW - Diet Surveys KW - Case-Control Studies KW - Aged KW - Male KW - China KW - Prostatic Neoplasms -- etiology KW - Food Preservatives -- adverse effects KW - Diet UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66652786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=British+journal+of+cancer&rft.atitle=Do+preserved+foods+increase+prostate+cancer+risk%3F&rft.au=Jian%2C+L%3BZhang%2C+D+H%3BLee%2C+A+H%3BBinns%2C+C+W&rft.aulast=Jian&rft.aufirst=L&rft.date=2004-05-04&rft.volume=90&rft.issue=9&rft.spage=1792&rft.isbn=&rft.btitle=&rft.title=British+journal+of+cancer&rft.issn=00070920&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-07-15 N1 - Date created - 2004-06-21 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Int J Cancer. 2000 May 1;86(3):421-4 [10760832] Med Sci Sports Exerc. 2000 Sep;32(9 Suppl):S498-504 [10993420] Int J Epidemiol. 2001 Apr;30(2):341-9 [11369740] Br J Cancer. 2002 Mar 4;86(5):712-7 [11875731] Cancer Epidemiol Biomarkers Prev. 2003 Mar;12(3):201-8 [12646508] Int J Cancer. 2004 Jan 1;108(1):130-5 [14618627] Lung Cancer. 1999 Sep;25(3):147-59 [10512125] Int J Cancer. 1994 Jul 15;58(2):197-202 [8026881] Neoplasma. 1996;43(1):61-3 [8843963] Int J Cancer. 1997;Suppl 10:2-6 [9209011] Cancer Res. 1997 Nov 15;57(22):5077-85 [9371506] Int J Cancer. 1998 May 29;76(5):659-64 [9610722] Br J Cancer. 1999 Jun;80(7):1107-13 [10362125] J Natl Cancer Inst. 1990 Jun 6;82(11):915-26 [2342126] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Measurement and prediction of METs during household activities in 35- to 45-year-old females AN - 954615743; 14081782 AB - This study determined whether four self-paced household tasks, conducted in the subjects' homes and a standardised laboratory environment, were performed at a moderate intensity [3-6 metabolic equivalents (METs)] in a representative sample of thirty-six 35- to 45-year-old females. Energy expenditure was also predicted via indirect methods. Self-paced energy expenditure during sweeping, window cleaning, vacuuming and mowing was measured using the Douglas bag technique. Heart rate, respiratory frequency, Computer Science Applications (CSA) movement counts (hip and wrist), Borg rating of perceived exertion and Quetelet's index were also recorded as potential predictors of energy expenditure. While the four activities were performed at mean intensities greater than or equal to 3.0 METs in both the home and laboratory, all comparisons between these two environments were statistically significant (P<0.001). The 95% confidence intervals (CIs) for the home and laboratory prediction equations were plus or minus 1.1 METs and plus or minus 1.0 MET, respectively. These data suggest that the aforementioned household chores can contribute to the 30min.day super(-1) of moderate-intensity activity required to confer health benefits. However, the substantial between-subject variability in energy expenditure resulted in some persons performing these tasks at a light intensity (<3.0 METs). The significant MET differences between the home and laboratory emphasise the effects of 'environment and terrain' and the 'mental approach to a task' on self-paced energy expenditure. Considering the means for the five activities ranged from 3.1 METs to 6.0 METs, the 95% CIs for the regression equations lack predictive precision. JF - European Journal of Applied Physiology AU - Brooks, Anthony G AU - Withers, Robert T AU - Gore, Christopher J AU - Vogler, Andrew J AU - Plummer, John AU - Cormack, John AD - Exercise Physiology Laboratory, School of Education, Flinders University, G.P.O. Box 2100, Adelaide, South Australia, Australia, 5001, bob.withers@flinders.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 638 EP - 648 PB - Springer-Verlag, P.O. Box 2485 Secaucus NJ 07096-2485 USA VL - 91 IS - 5-6 SN - 1439-6319, 1439-6319 KW - Physical Education Index KW - Energy cost KW - Measurement KW - Home KW - Statistics KW - Heart rate KW - Baseball KW - Activities KW - Wrists KW - Professional sports KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954615743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Applied+Physiology&rft.atitle=Measurement+and+prediction+of+METs+during+household+activities+in+35-+to+45-year-old+females&rft.au=Brooks%2C+Anthony+G%3BWithers%2C+Robert+T%3BGore%2C+Christopher+J%3BVogler%2C+Andrew+J%3BPlummer%2C+John%3BCormack%2C+John&rft.aulast=Brooks&rft.aufirst=Anthony&rft.date=2004-05-01&rft.volume=91&rft.issue=5-6&rft.spage=638&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Applied+Physiology&rft.issn=14396319&rft_id=info:doi/10.1007%2Fs00421-003-1018-9 LA - English DB - Physical Education Index N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - Energy cost; Measurement; Statistics; Home; Heart rate; Baseball; Wrists; Activities; Professional sports DO - http://dx.doi.org/10.1007/s00421-003-1018-9 ER - TY - JOUR T1 - Osteogenic Protein-1 inhibits matrix depletion in a hyaluronan hexasaccharide-induced model of osteoarthritis. AN - 71849721; 15094136 AB - To examine the capacity of recombinant osteogenic protein-1 (OP-1) to inhibit the cartilage extracellular matrix damage that follows treatment with hyaluronan hexasaccharides (HA6). The effects of OP-1 were examined on isolated human chondrocytes grown in alginate beads as well as articular cartilage slices treated with hyaluronan hexasaccharides. Changes in the relative expression of messenger RNA for hyaluronan synthase- 2, aggrecan and CD44 were determined by competitive quantitative reverse transcriptase-polymerase chain reaction. Cartilage proteoglycan biosynthesis was examined by a (35)S-sulfate incorporation assay. Cell-associated matrix of human chondrocytes was visualized by the use of particle exclusion assay, and alcian blue staining. Cartilage slices were examined for accumulation of proteoglycan by Safranin-O, and hyaluronan by a specific biotinylated probe. Combined OP-1 and HA6 treatment resulted in enhanced expression of mRNA for aggrecan and HAS-2, compared to the treatment with HA6 only. This increased expression of aggrecan mRNA was paralleled by an increased synthesis of cartilage proteoglycan especially retained in the cell-associated matrix. Co-treatment with OP-1 inhibited the HA6-induced depletion of cell-associated matrices as well as HA6-induced depletion of hyaluronan and proteoglycan within cartilage tissue slices. These results demonstrate that OP-1 can abrogate the catabolic events associated with a HA6-induced matrix depletion model of osteoarthritis. The mRNA levels of two major cartilage extracellular matrix components, aggrecan and hyaluronan synthase-2 are enhanced above values obtained by either OP-1 or HA6 treatments alone. JF - Osteoarthritis and cartilage AU - Nishida, Yoshihiro AU - Knudson, Cheryl B AU - Knudson, Warren AD - Department of Biochemistry, Rush Medical College, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, USA. Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 374 EP - 382 VL - 12 IS - 5 SN - 1063-4584, 1063-4584 KW - Aggrecans KW - 0 KW - Antigens, CD44 KW - BMP7 protein, human KW - Bone Morphogenetic Protein 7 KW - Bone Morphogenetic Proteins KW - Extracellular Matrix Proteins KW - Lectins, C-Type KW - Proteins KW - Proteoglycans KW - Transforming Growth Factor beta KW - RNA KW - 63231-63-0 KW - Hyaluronic Acid KW - 9004-61-9 KW - Transferases KW - EC 2.- KW - HAS2 protein, human KW - EC 2.4.1.- KW - Glucuronosyltransferase KW - EC 2.4.1.17 KW - hyaluronan synthase KW - EC 2.4.1.212 KW - ACVR1 protein, human KW - EC 2.7.11.30 KW - Activin Receptors, Type I KW - Index Medicus KW - Proteoglycans -- biosynthesis KW - Humans KW - Aged KW - Glucuronosyltransferase -- metabolism KW - Antigens, CD44 -- metabolism KW - Transferases -- metabolism KW - Extracellular Matrix Proteins -- metabolism KW - Proteoglycans -- metabolism KW - RNA -- metabolism KW - Cells, Cultured KW - Adult KW - Bone Morphogenetic Proteins -- metabolism KW - Middle Aged KW - Transforming Growth Factor beta -- metabolism KW - Chondrocytes -- metabolism KW - Proteins -- pharmacology KW - Extracellular Matrix -- drug effects KW - Cartilage, Articular -- metabolism KW - Osteoarthritis -- metabolism KW - Extracellular Matrix -- metabolism KW - Hyaluronic Acid -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71849721?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Osteoarthritis+and+cartilage&rft.atitle=Osteogenic+Protein-1+inhibits+matrix+depletion+in+a+hyaluronan+hexasaccharide-induced+model+of+osteoarthritis.&rft.au=Nishida%2C+Yoshihiro%3BKnudson%2C+Cheryl+B%3BKnudson%2C+Warren&rft.aulast=Nishida&rft.aufirst=Yoshihiro&rft.date=2004-05-01&rft.volume=12&rft.issue=5&rft.spage=374&rft.isbn=&rft.btitle=&rft.title=Osteoarthritis+and+cartilage&rft.issn=10634584&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-02 N1 - Date created - 2004-04-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The Australian Air Quality Forecasting System. Part II: Case Study of a Sydney 7-Day Photochemical Smog Event AN - 28453315; 200504-31-07927 (CE); 05988790 (EN); A05-45-14032 (AH) AB - The performance of the Australian Air Quality Forecasting System (AAQFS) is examined by means of a case study of a 7-day photochemical smog event in the Sydney region. This was the worst smog event for the 2000/ 01 oxidant season, and, because of its prolonged nature, it provided the opportunity to demonstrate the ability of AAQFS to forecast situations involving recirculation of precursors and remnant ozone, fumigation, and complex meteorological dynamics. The forecasting system was able to successfully predict high values of ozone, although at times the peak concentrations for the inland stations were underestimated. The dynamics for the Sydney region require a sensitive balance between the synoptic and mesoscale flows. Often high concentrations of ozone were advected inland by the sea breeze. On two occasions the system forecast a synoptic flow that was too strong, which blocked the inland advancement of the sea breeze. The peak ozone forecasts were underpredicted at the inland stations on those occasions. An examination of possible factors causing forecast errors has indicated that the AAQFS is more sensitive to errors in the meteorological conditions, rather than in the emissions or chemical mechanism in the Sydney region. JF - Journal of Applied Meteorology AU - Hess, G D AU - Tory, K J AU - Cope, M E AU - Lee, S AU - Puri, K AU - Manins, P C AU - Young, M AD - Corresponding author address: G. D. Hess, Bureau of Meteorology Research Centre, GPO Box 1289K, Melbourne VIC 3001, Australia. hess@bom.gov.au PY - 2004 SP - 663 EP - 679 PB - American Meteorological Society, 45 Beacon St , Boston, MA, 02108, USA, [mailto:amsinfo@ametsoc.org], [URL:http://www.ametsoc.org/ams] VL - 43 IS - 5 SN - 0894-8763, 0894-8763 KW - Civil Engineering (CE); Environmental Engineering (EN); Aerospace & High Technology (AH) KW - Air pollution KW - Cities KW - Mesoscale phenomena KW - Photochemical reactions KW - Meteorological parameters KW - Ozone KW - Smog KW - Air quality KW - Error detection KW - Sea breeze KW - Oxidizing agents KW - Australia KW - Article KW - EE 20:Air Pollution: Monitoring, Control & Remediation (EN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/28453315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=The+Australian+Air+Quality+Forecasting+System.+Part+II%3A+Case+Study+of+a+Sydney+7-Day+Photochemical+Smog+Event&rft.au=Hess%2C+G+D%3BTory%2C+K+J%3BCope%2C+M+E%3BLee%2C+S%3BPuri%2C+K%3BManins%2C+P+C%3BYoung%2C+M&rft.aulast=Hess&rft.aufirst=G&rft.date=2004-05-01&rft.volume=43&rft.issue=5&rft.spage=663&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2F2094.1 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-11-11 DO - http://dx.doi.org/10.1175/2094.1 ER - TY - JOUR T1 - The Australian Air Quality Forecasting System. Part III: Case Study of a Melbourne 4-Day Photochemical Smog Event AN - 28428246; 200504-31-07928 (CE); 05988791 (EN); A05-45-14033 (AH) AB - A 4-day photochemical smog event in the Melbourne, Victoria, Australia, region (6-9 March 2001) is examined to assess the performance of the Australian Air Quality Forecasting System (AAQFS). Although peak ozone concentrations measured during this period did not exceed the 1-h national air quality standard of 100 ppb, elevated maximum ozone concentrations in the range of 50-80 ppb were recorded at a number of monitoring stations on all four days. These maximum values were in general very well forecast by the AAQFS. On all but the third day the system predicted the advection of ozone precursors over Port Phillip (the adjacent bay) during the morning, where, later in the day, relatively high ozone concentrations developed. The ozone was advected back inland by bay and sea breezes. On the third day, a southerly component to the background wind direction prevented the precursor drainage over the bay, and the characteristic ozone cycle was disrupted. The success of the system's ability to predict peak ozone at individual monitoring stations was largely dependent on the direction and penetration of the sea and bay breezes, which in turn were dependent on the delicate balance between these winds and the opposing synoptic flow. JF - Journal of Applied Meteorology AU - Tory, K J AU - Cope, M E AU - Hess, G D AU - Lee, S AU - Puri, K AU - Manins, P C AU - Wong, N AD - Bureau of Meteorology Research Centre, GPO Box 1289K, Melbourne, VIC 3001, Australia tory@bom.gov.au PY - 2004 SP - 680 EP - 695 PB - American Meteorological Society, 45 Beacon St , Boston, MA, 02108, USA, [mailto:amsinfo@ametsoc.org], [URL:http://www.ametsoc.org/ams] VL - 43 IS - 5 SN - 0894-8763, 0894-8763 KW - Civil Engineering (CE); Environmental Engineering (EN); Aerospace & High Technology (AH) KW - Air pollution KW - Synoptic meteorology KW - Diurnal variations KW - Ozone KW - Air quality KW - Smog KW - Weather forecasting KW - Sea breezes KW - Wind direction KW - Drainage KW - Article KW - EE 20:Air Pollution: Monitoring, Control & Remediation (EN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/28428246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=The+Australian+Air+Quality+Forecasting+System.+Part+III%3A+Case+Study+of+a+Melbourne+4-Day+Photochemical+Smog+Event&rft.au=Tory%2C+K+J%3BCope%2C+M+E%3BHess%2C+G+D%3BLee%2C+S%3BPuri%2C+K%3BManins%2C+P+C%3BWong%2C+N&rft.aulast=Tory&rft.aufirst=K&rft.date=2004-05-01&rft.volume=43&rft.issue=5&rft.spage=680&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2F2092.1 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-11-11 DO - http://dx.doi.org/10.1175/2092.1 ER - TY - JOUR T1 - Metals in Airborne Particulate Matter in Downtown Rio de Janeiro, Brazil AN - 21047865; 5982356 AB - Without abstract. JF - Bulletin of Environmental Contamination and Toxicology AU - Quiterio, S L AU - Escaleira, V AU - Sousa, CRS AU - Maia, LFPG AU - Arbilla, G AD - Physical Chemistry Department, Federal University of Rio de Janeiro, CT, Building A, Room 408, 21949-900, Cidade Universitaria, Rio de Janeiro, RJ, Brazil Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 916 EP - 922 PB - Springer-Verlag, Life Science Journals, 175 Fifth Ave. New York NY 10010 USA, [mailto:orders@springer-ny.com], [URL:http://www.springer-ny.com/] VL - 72 IS - 5 SN - 0007-4861, 0007-4861 KW - Toxicology Abstracts; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Brazil, Rio de Janeiro KW - Metals KW - Atmospheric pollution KW - Airborne particulates KW - Metals in aerosols KW - Air quality KW - Particulates KW - Chemical composition of aerosols KW - Urban areas KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21047865?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+Environmental+Contamination+and+Toxicology&rft.atitle=Metals+in+Airborne+Particulate+Matter+in+Downtown+Rio+de+Janeiro%2C+Brazil&rft.au=Quiterio%2C+S+L%3BEscaleira%2C+V%3BSousa%2C+CRS%3BMaia%2C+LFPG%3BArbilla%2C+G&rft.aulast=Quiterio&rft.aufirst=S&rft.date=2004-05-01&rft.volume=72&rft.issue=5&rft.spage=916&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+Environmental+Contamination+and+Toxicology&rft.issn=00074861&rft_id=info:doi/10.1007%2Fs00128-004-0331-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-02-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Metals; Airborne particulates; Atmospheric pollution; Air quality; Metals in aerosols; Chemical composition of aerosols; Particulates; Urban areas; Brazil, Rio de Janeiro DO - http://dx.doi.org/10.1007/s00128-004-0331-2 ER - TY - JOUR T1 - Emissions from a vehicle fitted to operate on either petrol or compressed natural gas AN - 19963287; 6906261 AB - The purpose of this work was to evaluate the physical and chemical properties of emission products from a six-cylinder sedan car under a variety of operating conditions, before and after it has been converted to compressed natural gas (CNG) fuel. The specific focus of the measurements was on emission levels and characteristics of ultra fine particles and the emission levels together with the emissions of gaseous pollutants for a range of operating conditions before and up to 3 months after the vehicle was converted are presented and discussed in the paper. The investigations showed that converting a petrol operating vehicle to CNG has the potential of reducing some of the emissions and thus risks, while it does not appear to have an impact on others. In particular there was no statistically significant change in the emission of particles for the vehicle operating on petrol, before the conversion, compared to the emissions for the vehicle operating on CNG, after the conversion. There was a significant lowering of emissions of total polycyclic aromatic hydrocarbons and formaldehyde when the vehicle was operated on CNG, and a reduction of global warming potential was also observed when the vehicle was run on CNG, but the later gain is only at high vehicle speeds/loads, and would thus have to be considered in view of traffic and transport models for the region (in these models vehicle speed is an important parameter). JF - Science of the Total Environment AU - Ristovski, Z AU - Morawska, L AU - Ayoko, G A AU - Johnson, G AU - Gilbert, D AU - Greenaway, C AD - International Laboratory for Air Quality and Health, Queensland University of Technology, G.P.O. 2434, Brisbane, Qld 4001, Australia, l.morawska@qut.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 179 EP - 194 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 323 IS - 1-3 SN - 0048-9697, 0048-9697 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts; Risk Abstracts KW - Author Keywords: Emissions KW - Natural gas KW - Global warming potential KW - Polycyclic aromatic hydrocarbons KW - Fuels KW - Statistical analysis KW - Velocity KW - Formaldehyde KW - Emission control KW - Particulates KW - Atmospheric pollution by motor vehicles KW - Polycyclic aromatic hydrocarbon emissions KW - Gaseous pollutants KW - Emission measurements KW - Global warming KW - Automotive exhaust emissions KW - Air pollution measurements KW - P 0000:AIR POLLUTION KW - M2 551.588:Environmental Influences (551.588) KW - R2 23050:Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19963287?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Science+of+the+Total+Environment&rft.atitle=Emissions+from+a+vehicle+fitted+to+operate+on+either+petrol+or+compressed+natural+gas&rft.au=Ristovski%2C+Z%3BMorawska%2C+L%3BAyoko%2C+G+A%3BJohnson%2C+G%3BGilbert%2C+D%3BGreenaway%2C+C&rft.aulast=Ristovski&rft.aufirst=Z&rft.date=2004-05-01&rft.volume=323&rft.issue=1-3&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=Science+of+the+Total+Environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2003.10.023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-12-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Gaseous pollutants; Statistical analysis; Global warming; Atmospheric pollution by motor vehicles; Polycyclic aromatic hydrocarbon emissions; Polycyclic aromatic hydrocarbons; Fuels; Emission measurements; Formaldehyde; Velocity; Emission control; Particulates; Automotive exhaust emissions; Natural gas; Air pollution measurements DO - http://dx.doi.org/10.1016/j.scitotenv.2003.10.023 ER - TY - JOUR T1 - Sexual Selection Under Scramble Competition: Mate Location and Mate Choice in the Eucalypt Leaf Beetle Chrysophtharta agricola (Chapuis) in the Field AN - 18058900; 6024063 AB - For males of many species, the number of offspring sired can depend on the number of females mated. While pre- and postcopulatory choice by females can affect the outcome of potential mate encounters, mate location is a necessary prerequisite to any possible courtship and subsequent mating. Mate location of Chrysophtharta agricola in the field was examined using sticky traps baited with sexually receptive conspecific beetles. More beetles were caught on traps baited with conspecific beetles of either sex than on control traps that contained foliage only. Furthermore, 94% of beetles captured on control traps were males, indicating that the mating system of Chrysophtharta agricola can be labeled prolonged searching scramble competition polyandry, in which receptive females are evenly dispersed spatially and temporally, and males search competitively for them. Operational sex ratios were 1:1 throughout the season. By sampling paired and unpaired beetles in the field, we found that beetles generally did not select mates based on body size. Furthermore, neither sex mated preferentially with partners that were uninfected by parasitic mites or with beetles of the same generation. In the absence of postcopulatory female choice, the ability of males to locate females may therefore be the most important trait in determining male mating success. JF - Journal of Insect Behavior AU - Nahrung, H F AU - Allen, G R AD - CRC for Sustainable Production Forestry, GPO Box 252-12, Hobart, and School of Agricultural Science, The University of Tasmania, GPO Box 252-54, Hobart, Tasmania 7001, Australia, h.nahrung@qut.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 353 EP - 366 PB - Kluwer Academic Publishers VL - 17 IS - 3 SN - 0892-7553, 0892-7553 KW - Coleoptera KW - Leaf beetles KW - Ecology Abstracts; Animal Behavior Abstracts; Entomology Abstracts KW - Polyandry KW - Sexual selection KW - Chrysophtharta agricola KW - Mate selection KW - Competition KW - Chrysomelidae KW - D 04659:Insects KW - Y 25423:Insects KW - Z 05192:Reproductive behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18058900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Insect+Behavior&rft.atitle=Sexual+Selection+Under+Scramble+Competition%3A+Mate+Location+and+Mate+Choice+in+the+Eucalypt+Leaf+Beetle+Chrysophtharta+agricola+%28Chapuis%29+in+the+Field&rft.au=Nahrung%2C+H+F%3BAllen%2C+G+R&rft.aulast=Nahrung&rft.aufirst=H&rft.date=2004-05-01&rft.volume=17&rft.issue=3&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Journal+of+Insect+Behavior&rft.issn=08927553&rft_id=info:doi/10.1023%2FB%3AJOIR.0000031536.59988.0d LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Chrysophtharta agricola; Chrysomelidae; Competition; Sexual selection; Mate selection; Polyandry DO - http://dx.doi.org/10.1023/B:JOIR.0000031536.59988.0d ER - TY - JOUR T1 - Biogeochemical marine ecosystem models I: IGBEM--a model of marine bay ecosystems AN - 18056179; 5887208 AB - The Integrated Generic Bay Ecosystem Model (IGBEM) is presented. It is a coupled physical transport-biogeochemical process model constructed as a basis to explore the effects of model structure and complexity. The foundations for the model are two existing models, the European Regional Seas Ecosystem Model II (ERSEM II) and the Port Phillip Bay Integrated Model (PPBIM). Additional functional groups (such as benthic herbivorous invertebrates) and modules (dealing with sediment chemistry and mixing) have been incorporated or modified to ensure a more complete representation of temperate bay ecosystems and their processes, and a seamless amalgam of ERSEM II and PPBIM. The standard form of the entire model compares well with real ecosystems, such as Port Phillip Bay in Australia, and conforms to general ecological checkpoints such as the expected Sheldon Spectrum and Monbet's relationship between chlorophyll a and dissolved inorganic nitrogen. The model also produces spatial zonation and long-term cycles characteristic of natural systems. Despite the model taking a generalised biomass per functional group form, it captures well the system dynamics and allows for exploration of the effects of ecological driving forces such as predation and competition. JF - Ecological Modelling AU - Fulton, E A AU - Smith, ADM AU - Johnson, C R AD - CSIRO Division of Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, beth.fulton@csiro.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 267 EP - 307 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 174 IS - 3 SN - 0304-3800, 0304-3800 KW - ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Chlorophylls KW - Ecosystems KW - Predation KW - Nutrient cycles KW - Ecosystem models KW - PSE, Australia, Victoria, Port Phillip Bay KW - Interspecific relationships KW - Marine environment KW - Transport processes KW - Biotic factors KW - Competition KW - Temperate zones KW - Bays KW - Modelling KW - Abiotic factors KW - Marine KW - Sediment chemistry KW - Biogeochemical cycle KW - Biogeochemistry KW - Energy flow KW - Zoobenthos KW - Bay dynamics KW - Plankton KW - Nitrogen KW - Benthos KW - Q1 08482:Ecosystems and energetics KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18056179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Biogeochemical+marine+ecosystem+models+I%3A+IGBEM--a+model+of+marine+bay+ecosystems&rft.au=Fulton%2C+E+A%3BSmith%2C+ADM%3BJohnson%2C+C+R&rft.aulast=Fulton&rft.aufirst=E&rft.date=2004-05-01&rft.volume=174&rft.issue=3&rft.spage=267&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.09.027 LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Sediment chemistry; Chlorophylls; Ecosystems; Biogeochemistry; Biogeochemical cycle; Predation; Nutrient cycles; Energy flow; Interspecific relationships; Transport processes; Zoobenthos; Biotic factors; Bay dynamics; Competition; Temperate zones; Plankton; Abiotic factors; Benthos; Modelling; Nitrogen; Bays; Marine environment; Ecosystem models; PSE, Australia, Victoria, Port Phillip Bay; Marine DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.09.027 ER - TY - JOUR T1 - Enhanced vigilance in groups in Egernia stokesii, a lizard with stable social aggregations AN - 18019044; 5967224 AB - The Australian gidgee skink Egernia stokesii is unusual among lizards in that it maintains stable social aggregations of related individuals. Experiments were conducted to investigate whether lizards living in groups gained benefits from the collective detection of approaching threats. In captive colonies, lizards living in a group detected an approaching threat earlier than lizards alone, and lizards basking in a group spent more time in a non-vigilant, eyes-closed, state than lizards alone. These results imply that individuals in this species gain from the enhanced vigilance associated with group membership. Since many juveniles remain within their natal groups, group vigilance may enhance inclusive fitness. JF - Journal of Zoology AU - Lanham, E J AU - Bull, C M AD - School of Biological Sciences, Flinders University of South Australia, GPO Box 2100, Adelaide, SA 5001, Australia, michael.bull@flinders.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 95 EP - 99 VL - 263 IS - 1 SN - 0952-8369, 0952-8369 KW - Animal Behavior Abstracts; Ecology Abstracts KW - Fitness KW - Social organization KW - Group size KW - Egernia stokesii KW - Vigilance KW - Y 25504:Vertebrates (excluding fish, birds & mammals) KW - D 04670:Reptiles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18019044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Zoology&rft.atitle=Enhanced+vigilance+in+groups+in+Egernia+stokesii%2C+a+lizard+with+stable+social+aggregations&rft.au=Lanham%2C+E+J%3BBull%2C+C+M&rft.aulast=Lanham&rft.aufirst=E&rft.date=2004-05-01&rft.volume=263&rft.issue=1&rft.spage=95&rft.isbn=&rft.btitle=&rft.title=Journal+of+Zoology&rft.issn=09528369&rft_id=info:doi/10.1017%2FS0952836904004923 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Egernia stokesii; Social organization; Fitness; Group size; Vigilance DO - http://dx.doi.org/10.1017/S0952836904004923 ER - TY - JOUR T1 - Testing density-dependent groundwater models: two-dimensional steady state unstable convection in infinite, finite and inclined porous layers AN - 17983787; 5906287 AB - This study proposes the use of several problems of unstable steady state convection with variable fluid density in a porous layer of infinite horizontal extent as two-dimensional (2-D) test cases for density-dependent groundwater flow and solute transport simulators. Unlike existing density-dependent model benchmarks, these problems have well-defined stability criteria that are determined analytically. These analytical stability indicators can be compared with numerical model results to test the ability of a code to accurately simulate buoyancy driven flow and diffusion. The basic analytical solution is for a horizontally infinite fluid-filled porous layer in which fluid density decreases with depth. The proposed test problems include unstable convection in an infinite horizontal box, in a finite horizontal box, and in an infinite inclined box. A dimensionless Rayleigh number incorporating properties of the fluid and the porous media determines the stability of the layer in each case. Testing the ability of numerical codes to match both the critical Rayleigh number at which convection occurs and the wavelength of convection cells is an addition to the benchmark problems currently in use. The proposed test problems are modelled in 2-D using the SUTRA [SUTRA--A model for saturated-unsaturated variable-density ground-water flow with solute or energy transport. US Geological Survey Water-Resources Investigations Report, 02-4231, 2002. 250 p] density-dependent groundwater flow and solute transport code. For the case of an infinite horizontal box, SUTRA results show a distinct change from stable to unstable behaviour around the theoretical critical Rayleigh number of 4[pi] and the simulated wavelength of unstable convection agrees with that predicted by the analytical solution. The effects of finite layer aspect ratio and inclination on stability indicators are also tested and numerical results are in excellent agreement with theoretical stability criteria and with numerical results previously reported in traditional fluid mechanics literature. JF - Advances in Water Resources AU - Weatherill, D AU - Simmons, C T AU - Voss, C I AU - Robinson, NI AD - School of Chemistry, Physics and Earth Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia, douglas.weatherill@flinders.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 547 EP - 562 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 27 IS - 5 SN - 0309-1708, 0309-1708 KW - Water Resources Abstracts; Aqualine Abstracts KW - Convection KW - Porous Media KW - Model Testing KW - Model Studies KW - Hydrologic Models KW - Groundwater Data KW - AQ 00001:Water Resources and Supplies KW - SW 0840:Groundwater UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17983787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Water+Resources&rft.atitle=Testing+density-dependent+groundwater+models%3A+two-dimensional+steady+state+unstable+convection+in+infinite%2C+finite+and+inclined+porous+layers&rft.au=Weatherill%2C+D%3BSimmons%2C+C+T%3BVoss%2C+C+I%3BRobinson%2C+NI&rft.aulast=Weatherill&rft.aufirst=D&rft.date=2004-05-01&rft.volume=27&rft.issue=5&rft.spage=547&rft.isbn=&rft.btitle=&rft.title=Advances+in+Water+Resources&rft.issn=03091708&rft_id=info:doi/10.1016%2Fj.advwatres.2004.01.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Convection; Hydrologic Models; Porous Media; Groundwater Data; Model Testing; Model Studies DO - http://dx.doi.org/10.1016/j.advwatres.2004.01.003 ER - TY - JOUR T1 - Evaluation of the Effectiveness of Court-Ordered Fisheries Management Policies AN - 17851959; 5962709 AB - Within the 1836 Treaty waters of the Laurentian Great Lakes, fisheries allocation and management between Native and state-licensed fishers was guided by a court-ordered policy, the 1985 Consent Order. This policy was created to promote rehabilitation of lake trout (Salvelinus namaycush), reduce social conflict, and provide a framework for joint fisheries management. Expiration of the order led to creation of a replacement policy, the 2000 Consent Decree. To assess effectiveness of the 1985 Consent Order and perceptions of the 2000 Consent Decree, we conducted 46 interviews with members of pertinent stakeholder groups and their representatives. Results indicated that most stakeholders believed the 1985 Consent Order was insufficient to promote lake trout rehabilitation. Most respondents outside the Grand Traverse Bay area perceived that social conflict decreased under this policy. Tribal and DNR biologists and representatives believed fisheries management improved and became more cooperative. Many biologists and representatives anticipated the 2000 Consent Decree would be more effective at promoting lake trout rehabilitation and cooperative joint management. In contrast to some fishers, these respondents did not expect social conflict under this policy. Results indicated that court-ordered policies should allocate fisheries to provide economic opportunities and incorporate institutionalized, collaborative management processes. JF - Fisheries AU - Cimo, L F AU - Dobson, T Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 10 EP - 18 VL - 29 IS - 5 SN - 0363-2415, 0363-2415 KW - Lake trout KW - Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Stakeholders KW - Policies KW - Social aspects KW - Fishery regulations KW - Freshwater KW - USA, Michigan, Michigan L., Grand Traverse Bay KW - Fishery policy KW - Lakes KW - Fishery management KW - Inland fisheries KW - Environmental restoration KW - Cooperatives KW - Salvelinus namaycush KW - Disputes KW - M3 1130:Water KW - Q1 08604:Stock assessment and management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17851959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fisheries&rft.atitle=Evaluation+of+the+Effectiveness+of+Court-Ordered+Fisheries+Management+Policies&rft.au=Cimo%2C+L+F%3BDobson%2C+T&rft.aulast=Cimo&rft.aufirst=L&rft.date=2004-05-01&rft.volume=29&rft.issue=5&rft.spage=10&rft.isbn=&rft.btitle=&rft.title=Fisheries&rft.issn=03632415&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Policies; Fishery management; Inland fisheries; Fishery regulations; Disputes; Fishery policy; Stakeholders; Lakes; Cooperatives; Environmental restoration; Social aspects; Salvelinus namaycush; USA, Michigan, Michigan L., Grand Traverse Bay; Freshwater ER - TY - JOUR T1 - The determination of trace metal pollutants in environmental matrices using ion chromatography AN - 17210466; 6904719 AB - A review is presented detailing the development of ion chromatography (IC) as a selective analytical tool for the determination of toxic metals and their organic species in many environmental sample matrices. A brief outline of ion chromatographic principles, together with an overview of the stationary phases used to separate metals, namely ion exchangers, modified ion pair sorbents and chelating ion exchangers, and the methods for detecting metal ions including hyphenation with spectroscopy and sample preparation schemes are also given, prior to a critical examination of developed methods for various metals including arsenic, chromium, cadmium, lead, mercury, beryllium, aluminium and uranium since 1990. JF - Environment International AU - Shaw, Matthew J AU - Haddad, Paul R AD - Australian Centre for Research on Separation Science, School of Chemistry, University of Tasmania, GPO Box 252-75, Private Bag 75, Hobart 7001, Tasmania, Australia, Paul.Haddad@utas.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 403 EP - 431 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 30 IS - 3 SN - 0160-4120, 0160-4120 KW - Pollution Abstracts KW - Author Keywords: Ion chromatography KW - Chelation KW - Metal ions KW - Hyphenation KW - ICP-MS KW - Post-column reaction KW - Environmental monitoring KW - Arsenic KW - Chromium KW - Chromatography KW - Heavy metals KW - Lead KW - Monitoring methods KW - Reviews KW - Uranium KW - Beryllium KW - Aluminum KW - Mercury KW - Cadmium KW - Ion exchange KW - Chemical analysis KW - Trace metals KW - P 9000:ENVIRONMENTAL ACTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17210466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environment+International&rft.atitle=The+determination+of+trace+metal+pollutants+in+environmental+matrices+using+ion+chromatography&rft.au=Shaw%2C+Matthew+J%3BHaddad%2C+Paul+R&rft.aulast=Shaw&rft.aufirst=Matthew&rft.date=2004-05-01&rft.volume=30&rft.issue=3&rft.spage=403&rft.isbn=&rft.btitle=&rft.title=Environment+International&rft.issn=01604120&rft_id=info:doi/10.1016%2Fj.envint.2003.09.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-09-01 N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Arsenic; Chromium; Heavy metals; Chromatography; Lead; Monitoring methods; Uranium; Reviews; Aluminum; Beryllium; Mercury; Cadmium; Chemical analysis; Ion exchange; Trace metals DO - http://dx.doi.org/10.1016/j.envint.2003.09.009 ER - TY - JOUR T1 - Does greater night-time, rather than constant, warming alter growth of managed pasture under under ambient and elevated atmospheric CO sub(2)? AN - 17099340; 6636326 AB - This study examined the effects of warming, elevated atmospheric CO sub(2) and cutting regimen on the growth of Phalaris aquatica cv. Holdfast swards. Six temperature gradient tunnels (TGT) were used to manipulate both air temperature and atmospheric CO sub(2) concentrations (ambient and 750 ppm). Within each tunnel, there were three temperature treatments: no warming, constant warming of +3.0 degree C and a daytime warming of 2.2 degree C combined with a night-time warming of 4.0 degree C and two defoliation frequencies. Averaged across 20 months of growth, there was a positive effect of elevated atmospheric CO sub(2) (+11%), no effect of either warming treatment and a negative effect of frequent cutting (-19%) on total above ground biomass production. The responses to all treatments, however, were strongly seasonal. Positive responses to CO sub(2) were statistically significant only in the spring, when plant growth was strongest. No evidence was found that high night-time warming had different effects on plant growth and plant responses to elevated atmospheric CO sub(2), than constant warming. JF - New Phytologist AU - Volder, A AU - Edwards, E J AU - Evans, J R AU - Robertson, B C AU - Schortemeyer, M AU - Gifford, R M AD - Cooperative Research Centre for Greenhouse Accounting, GPO Box 475, Canberra, ACT 2601, Australia; CSIRO Plant Industry, GPO Box 1600, Canberra, ACT 2601, Australia, Astrid.Volder@csiro.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 397 EP - 411 PB - Blackwell Publishing Ltd., 9600 Garsington Road Oxford OX4 2DQ UK, [URL:http://www.blackwellpublishing.com] VL - 162 IS - 2 SN - 0028-646X, 0028-646X KW - Ecology Abstracts KW - Temperature effects KW - Daytime KW - Phalaris aquatica KW - Statistical analysis KW - Defoliation KW - Carbon dioxide KW - Tunnels KW - Biomass KW - Pasture KW - Air temperature KW - D 04625:Plants - general UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17099340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=New+Phytologist&rft.atitle=Does+greater+night-time%2C+rather+than+constant%2C+warming+alter+growth+of+managed+pasture+under+under+ambient+and+elevated+atmospheric+CO+sub%282%29%3F&rft.au=Volder%2C+A%3BEdwards%2C+E+J%3BEvans%2C+J+R%3BRobertson%2C+B+C%3BSchortemeyer%2C+M%3BGifford%2C+R+M&rft.aulast=Volder&rft.aufirst=A&rft.date=2004-05-01&rft.volume=162&rft.issue=2&rft.spage=397&rft.isbn=&rft.btitle=&rft.title=New+Phytologist&rft.issn=0028646X&rft_id=info:doi/10.1111%2Fj.1469-8137.2004.01025.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-07-01 N1 - SuppNotes - Figures, 8; tables, 2; formulas, 28; references, 44. N1 - Last updated - 2015-03-25 N1 - SubjectsTermNotLitGenreText - Temperature effects; Daytime; Statistical analysis; Defoliation; Biomass; Tunnels; Carbon dioxide; Pasture; Air temperature; Phalaris aquatica DO - http://dx.doi.org/10.1111/j.1469-8137.2004.01025.x ER - TY - JOUR T1 - New methods of determination of average particle emission factors for two groups of vehicles on a busy road AN - 16169179; 5879164 AB - In this paper, two new methods are developed for the determination of the average emission factors of fine and ultra-fine particles for different groups of vehicles on a busy road. The values of these emission factors for heavy-duty trucks and light-duty cars are calculated, discussed, and compared with the previous results obtained mainly in laboratory conditions. JF - Atmospheric Environment AU - Gramotnev, G AU - Ristovski, Z D AU - Brown, R J AU - Madl, P AD - International Laboratory for Air Quality and Health, School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane QLD 4001, Australia., g.gramotnev@qut.edu.au Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 2607 EP - 2610 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 38 IS - 16 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Air pollution KW - Pollution monitoring KW - Particulate matter emissions KW - Motor vehicles KW - Particulates KW - Exhaust emissions KW - Particulate matter from motor vehicles KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16169179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=New+methods+of+determination+of+average+particle+emission+factors+for+two+groups+of+vehicles+on+a+busy+road&rft.au=Gramotnev%2C+G%3BRistovski%2C+Z+D%3BBrown%2C+R+J%3BMadl%2C+P&rft.aulast=Gramotnev&rft.aufirst=G&rft.date=2004-05-01&rft.volume=38&rft.issue=16&rft.spage=2607&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2004.02.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2004-06-01 N1 - Last updated - 2015-03-24 N1 - SubjectsTermNotLitGenreText - Particulate matter emissions; Particulate matter from motor vehicles; Air pollution; Pollution monitoring; Motor vehicles; Particulates; Exhaust emissions DO - http://dx.doi.org/10.1016/j.atmosenv.2004.02.015 ER - TY - JOUR T1 - Medications as a Source of Human Exposure to Phthalates AN - 14711973; 10662615 JF - Environmental Health Perspectives AU - Hauser, Russ AU - Duty, Susan AU - Godfrey-Bailey, Linda AU - Calafat, Antonia M Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 751 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEDICAL SURVEILLANCE KW - PHTHALIC ACID ESTERS KW - DRUGS KW - BIOACCUMULATION, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14711973?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Medications+as+a+Source+of+Human+Exposure+to+Phthalates&rft.au=Hauser%2C+Russ%3BDuty%2C+Susan%3BGodfrey-Bailey%2C+Linda%3BCalafat%2C+Antonia+M&rft.aulast=Hauser&rft.aufirst=Russ&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=751&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEDICAL SURVEILLANCE; PHTHALIC ACID ESTERS; DRUGS; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Urinary 8-Hydroxy-2'-Deoxyguanosine as a Biomarker of Oxidative DNA Damage in Workers Exposed to Fine Particulates AN - 14711931; 10662604 AB - In a group of boilermakers working at a power plant during an overhaul of oil-fired boilers, the association between personal exposure to fine particulate matter and oxidative DNA damage and repair, as indicated by urinary levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), was investigated. The workers were monitored over five consecutive workdays, and chemical analysis of the particulate sample was performed to determine exposure to vanadium, chromium, manganese, nickel, copper, and lead. Results showed that the median total PM sub(2.5) 8-h time-weighted average concentration was 0.44 mg/m super(3), ranging 0.290.76 mg/m super(3). Among the metals, exposures to V and Cr were highest and lowest, respectively, and each of the metal concentrations was correlated moderately to highly with total PM sub(2.5) concentrations. The mean pre-workshift 8-OHdG concentration was 13.26 mu g/g creatinine, and the mean of the cross-shift change was 1.88 mu g/g creatinine. Crude analyses revealed a significant association between PM sub(2.5) 8-h time-weighted average concentrations and urinary 8-OHdG concentrations, and the association remained statistically significant after adjusting for urinary cotinine levels, chronic bronchitis status, and age. Concentrations of V, Mn, Ni, and Pb in PM sub(2.5) showed a statistically significant association with 8-OHdG concentrations. JF - Environmental Health Perspectives AU - Kim, Jee Young AU - Mukherjee, Sutapa AU - Ngo, Long AU - Christiani, David C Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 666 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BIOLOGICAL INDICATORS KW - PARTICULATES KW - HEALTH SAFETY, OCCUPATIONAL KW - HEAVY METALS KW - DNA KW - OXIDANT STRESS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14711931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Urinary+8-Hydroxy-2%27-Deoxyguanosine+as+a+Biomarker+of+Oxidative+DNA+Damage+in+Workers+Exposed+to+Fine+Particulates&rft.au=Kim%2C+Jee+Young%3BMukherjee%2C+Sutapa%3BNgo%2C+Long%3BChristiani%2C+David+C&rft.aulast=Kim&rft.aufirst=Jee&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=666&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HEALTH SAFETY, OCCUPATIONAL; BIOLOGICAL INDICATORS; HEAVY METALS; DNA; OXIDANT STRESS; PARTICULATES ER - TY - JOUR T1 - Health and Environmental Consequences of the World Trade Center Disaster AN - 14711002; 10662613 AB - Results are summarized from a comprehensive assessment of the impact of the chemical contaminants generated by the World Trade Center disaster in September 2001 on human health and the environment. Considered were the effects of settled dust, airborne particulate matter (PM), trace elements in PM sub(2.5), dioxin and other chlorinated compounds, asbestos, and airborne PAHs. Multi-element analyses of airborne samples collected at Ground Zero were used to generate chemical profiles that could identify specific sources of emission, and satellite images were used to characterize the spatial distribution of the material released to the atmosphere. Health risks were assessed in firefighters, cleanup and recovery workers, and community residents. The data show that exposures to chemical contaminants were not uniform following the disaster, as there were sharp gradients by time after the attack and by distance from Ground Zero. Extremely high exposures occurred in the first few hours and days, and transient increases were noted when the rubble was disturbed and fires flared. Diesel exhaust became an important contaminant during the cleanup phase, and asbestos was problematic early on. In addition, airborne dioxin levels were elevated substantially in the initial days following the disaster. In firefighters, police, and other first-responders, a positive relationship was found between intensity and duration of exposure and the severity of pulmonary effects as well as of PM levels in sputum, and an increase in the incidence of small-for-gestational-age was the major adverse health effect seen in infants borne to women who were inside the towers or within approximately ten blocks of the Work Trade Center. JF - Environmental Health Perspectives AU - Landrigan, Philip J AU - Lioy, Paul J AU - Thurston, George AU - Berkowitz, Gertrud AU - Chen, L C AU - Chillrud, Steven N AU - Gavett, Stephen H Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 731 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - ASBESTOS KW - RESPIRABLE DUST KW - PARTICULATES KW - RISK ASSESSMENT KW - HEALTH SAFETY, OCCUPATIONAL KW - REPRODUCTION, HUMAN KW - PULMONARY EFFECTS KW - DIOXINS KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14711002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Health+and+Environmental+Consequences+of+the+World+Trade+Center+Disaster&rft.au=Landrigan%2C+Philip+J%3BLioy%2C+Paul+J%3BThurston%2C+George%3BBerkowitz%2C+Gertrud%3BChen%2C+L+C%3BChillrud%2C+Steven+N%3BGavett%2C+Stephen+H&rft.aulast=Landrigan&rft.aufirst=Philip&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=731&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; HEALTH SAFETY, OCCUPATIONAL; AIR POLLUTION EFFECTS; REPRODUCTION, HUMAN; ASBESTOS; PULMONARY EFFECTS; DIOXINS; RESPIRABLE DUST; PARTICULATES; NEW YORK CITY ER - TY - JOUR T1 - Backward Estimation of Exposure to Organochlorines Using Repeated Measurements AN - 14710986; 10662611 AB - Three different backward extrapolation models were compared to estimate exposure to PCBs using data collected during three surveys that spanned 197391. The surveys focused on exposure to PCBs through consumption of sport-caught fish in Michigan. The surveys, conducted by the Michigan Department of Community Health, spanned 197374, 197982, and 198991. The three models, which are described briefly, were applied to determine the extent to which estimated PCB levels concurred with PCB concentrations measured in the past. Two backward extrapolation equations, one from 1991 through 1979 and one from 1982 through 1973, were tested for each model. Results showed that the simple decay model led to large overestimation of past exposures, while the backward exposure assessment that employed changing fish PCB levels and reduction due to breast-feeding produced an acceptable fit. The regression model based on repeated measurements, however, led to the best overall PCB estimations at each survey period. JF - Environmental Health Perspectives AU - Karmaus, Wilfried AU - Fussman, Christopher AU - Muttineni, Jyotsna AU - Zhu, Xiaobei Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 710 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - MICHIGAN KW - MATHEMATIC MODELS, BIOLOGICAL KW - BIOACCUMULATION, HUMAN KW - FOOD CONTAMINATION KW - FISHING, SPORT KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710986?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Backward+Estimation+of+Exposure+to+Organochlorines+Using+Repeated+Measurements&rft.au=Karmaus%2C+Wilfried%3BFussman%2C+Christopher%3BMuttineni%2C+Jyotsna%3BZhu%2C+Xiaobei&rft.aulast=Karmaus&rft.aufirst=Wilfried&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=710&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FISHING, SPORT; POLYCHLORINATED BIPHENYLS; MICHIGAN; MATHEMATIC MODELS, BIOLOGICAL; BIOACCUMULATION, HUMAN; FOOD CONTAMINATION ER - TY - JOUR T1 - Low-Dose Agrochemicals and Lawn-Care Pesticides Induce Developmental Toxicity in Murine Preimplantation Embryos AN - 14710958; 10662610 JF - Environmental Health Perspectives AU - Greenlee, Anne R AU - Ells, Tammy M AU - Berg, Richard L Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 703 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - PESTICIDE USAGE, RESIDENTIAL KW - BIOASSAY KW - CHEMICAL CONTAMINATION, MULTIPLE KW - HERBICIDE EXPOSURE KW - REPRODUCTION, ANIMAL KW - PESTICIDE EXPOSURE KW - FUNGICIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14710958?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Low-Dose+Agrochemicals+and+Lawn-Care+Pesticides+Induce+Developmental+Toxicity+in+Murine+Preimplantation+Embryos&rft.au=Greenlee%2C+Anne+R%3BElls%2C+Tammy+M%3BBerg%2C+Richard+L&rft.aulast=Greenlee&rft.aufirst=Anne&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=703&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CHEMICAL CONTAMINATION, MULTIPLE; PESTICIDE USAGE, RESIDENTIAL; BIOASSAY; REPRODUCTION, ANIMAL; HERBICIDE EXPOSURE; PESTICIDE EXPOSURE; FUNGICIDES ER - TY - JOUR T1 - Biochemical Effect Evaluation of Perfluorooctane Sulfonic Acid-Contaminated Wood Mice (Apodemus sylvaticus) AN - 14709929; 10662607 AB - Wood mice Apodemus sylvaticus were collected at a nature reserve next to a fluorochemical production plant and at a reference location in Belgium, and liver concentrations of perfluorooctane sulfonic acid (PFOS) and some perfluorinated fatty acids were measured. Exposure effects on liver weight, relative liver weight, liver peroxisomal fatty acid beta -oxidation, and total protein content and catalase activity in the liver mitochondrial fraction were assessed, as were serum triglyceride and cholesterol levels, serum alanine aminotransferase activity, and serum potassium levels. Liver concentrations of PFOS at the exposed and reference sites ranged 0.47178.55 and 0.141.11 mu g/g, respectively, and perfluorocarboxylates were generally present at detectable concentrations in mice with the highest PFOS concentrations. Relative liver weights, mitochondrial fraction protein contents, peroxisomal beta -oxidation activity, and microsomal lipid peroxidation levels were significantly higher in mice from the exposed location. Relative liver weights and liver microsomal lipid peroxidation levels showed a significant relationship with liver PFOS concentrations. JF - Environmental Health Perspectives AU - Hoff, Philippe Tony AU - Scheirs, Jan AU - Van de Vijver, Kristin AU - Van Dongen, Walter AU - Esmans, Eddy Louis AU - Blust, Ronny AU - De Coen, Wim Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 681 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - FLUORINATED HYDROCARBONS KW - BIOACCUMULATION, ANIMAL KW - BIOCHEMISTRY KW - HEPATOTOXICITY KW - RODENTS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14709929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biochemical+Effect+Evaluation+of+Perfluorooctane+Sulfonic+Acid-Contaminated+Wood+Mice+%28Apodemus+sylvaticus%29&rft.au=Hoff%2C+Philippe+Tony%3BScheirs%2C+Jan%3BVan+de+Vijver%2C+Kristin%3BVan+Dongen%2C+Walter%3BEsmans%2C+Eddy+Louis%3BBlust%2C+Ronny%3BDe+Coen%2C+Wim&rft.aulast=Hoff&rft.aufirst=Philippe&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=681&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BIOACCUMULATION, ANIMAL; FLUORINATED HYDROCARBONS; HEPATOTOXICITY; BIOCHEMISTRY; RODENTS ER - TY - JOUR T1 - Probability Estimates for the Unique Childhood Leukemia Cluster in Fallon, Nevada, and Risks near Other U.S. Military Aviation Facilities AN - 14708837; 10662618 AB - From 1999 to 2001, 11 cases of leukemia were diagnosed among children residing in Churchill County, NV, and another five cases were identified among children who were not residents at the time of diagnosis but who had lived in the county at some point prior. Large military training operations are conducted at the naval air station located in the sparsely populated county. Age-standardized incidence rate ratios for childhood leukemia in Churchill County were calculated as a whole and for the time period that only included cases diagnosed after investigation of the cluster had begun in July 2000. In addition, using all counties covered by the Surveillance, Epidemiology, and End Results (SEER) Program and the California Cancer Registry, rates of childhood leukemia in counties with military aviation bases were compared with rates in counties without military bases. Results suggested that the Churchill County cluster was not due only to chance, as it represented a twelve-fold increase above leukemia rates in SEER registries. Analysis of the larger data revealed no increase in childhood leukemia among counties with military aviation bases compared to those without bases. JF - Environmental Health Perspectives AU - Steinmaus, Craig AU - Lu, Meng AU - Todd, Randall L AU - Smith, Allan H Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 766 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CANCER RISK KW - NEVADA KW - PATHOLOGY, CHILDREN KW - HUMAN T CELL LEUKEMIA VIRUS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708837?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Probability+Estimates+for+the+Unique+Childhood+Leukemia+Cluster+in+Fallon%2C+Nevada%2C+and+Risks+near+Other+U.S.+Military+Aviation+Facilities&rft.au=Steinmaus%2C+Craig%3BLu%2C+Meng%3BTodd%2C+Randall+L%3BSmith%2C+Allan+H&rft.aulast=Steinmaus&rft.aufirst=Craig&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=766&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 6 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CANCER RISK; NEVADA; PATHOLOGY, CHILDREN; HUMAN T CELL LEUKEMIA VIRUS ER - TY - JOUR T1 - Storage of Serum in Plastic and Glass Containers May Alter the Serum Concentration of Polychlorinated Biphenyls AN - 14708804; 10662600 AB - Data obtained during a study in Michigan that examined the relationship between PCB serum concentrations in humans and adverse reproduction effects were used to examine whether plastic containers used to store serum samples altered the concentrations of PCBs, polybrominated biphenyls (PBBs), and DDE in the samples. The phlebotomists stored the samples in glass containers, but the commercial analytical laboratory transferred the specimens to plastic containers for freezing. Results showed that, while the proportions of detectable halogenated organic compounds were not different with regard to samples kept in glass or plastic containers, storage in plastic containers altered the total concentrations of PCBs, especially the higher chlorinated congeners. The concentrations of DDT and PBBs were not affected, however. JF - Environmental Health Perspectives AU - Karmaus, Wilfried AU - Riebow, John F Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 643 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - POLYCHLORINATED BIPHENYLS KW - PLASTICS KW - MICHIGAN KW - DDE KW - BLOOD ANALYSIS KW - POLYBROMINATED BIPHENYLS KW - GLASS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708804?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Storage+of+Serum+in+Plastic+and+Glass+Containers+May+Alter+the+Serum+Concentration+of+Polychlorinated+Biphenyls&rft.au=Karmaus%2C+Wilfried%3BRiebow%2C+John+F&rft.aulast=Karmaus&rft.aufirst=Wilfried&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=643&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - POLYBROMINATED BIPHENYLS; POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; PLASTICS; DDE; MICHIGAN; GLASS ER - TY - JOUR T1 - Interlaboratory Comparison of Four in Vitro Assays for Assessing Androgenic and Antiandrogenic Activity of Environmental Chemicals AN - 14708661; 10662609 AB - Results from four laboratories were compared for four in vitro assays for measuring androgen receptor-mediated androgenic and antiandrogenic activity of selected environmental chemicals. The laboratories and cell types utilized are tabulated, along with the respective end point and exposure time. The test compounds included an androgen and an antiandrogen control, vinclozolin, 4-androsten-3,17-dione, 17 alpha -methyltestosterone, and tris-(4-chlorophenyl)methanol. One laboratory used cell number as the endpoint, and the other three used luciferase activity relative to the hormone-free negative control. All four test systems produced comparable quantitative results for the two androgens and two antiandrogens. However, the assay involving Chinese hamster ovary cells transiently transfected with pSVARO expression vector and MMTV-LUC reporter plasmid showed a generally greater sensitivity toward the detection of androgens. Overall, the coefficients of variation for the different EC sub(50) and IC sub(50) values were within the same range. JF - Environmental Health Perspectives AU - Korner, Wolfgang AU - Vinggaard, Anne Marie AU - Terouanne, Beatrice AU - Ma, Risheng AU - Wieloch, Carise AU - Schlumpf, Margret AU - Sultan, Charles Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 695 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - QUANTITATIVE ANALYSIS KW - HORMONAL EFFECTS KW - BIOASSAY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708661?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Interlaboratory+Comparison+of+Four+in+Vitro+Assays+for+Assessing+Androgenic+and+Antiandrogenic+Activity+of+Environmental+Chemicals&rft.au=Korner%2C+Wolfgang%3BVinggaard%2C+Anne+Marie%3BTerouanne%2C+Beatrice%3BMa%2C+Risheng%3BWieloch%2C+Carise%3BSchlumpf%2C+Margret%3BSultan%2C+Charles&rft.aulast=Korner&rft.aufirst=Wolfgang&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=695&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - QUANTITATIVE ANALYSIS; HORMONAL EFFECTS; BIOASSAY ER - TY - JOUR T1 - Retrospective Time-Trend Study of Polybrominated Diphenyl Ether and Polybrominated and Polychlorinated Biphenyl Levels in Human Serum from the United States AN - 14708618; 10662602 AB - Archived serum samples collected in the southeastern US over the period 19852002 and in Seattle, WA, over the period 19992002 were analyzed for concentrations of polybrominated diphenyl ethers (PBDEs), 2,2',4,4',5,5'-hexabromobiphenyl (PBB-153), and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153). The concentrations of all PBDEs, with the exception of BDE-85, increased significantly during the study period, while decreasing levels were found for PBB-153 and PCB-153. The decreasing trend for the latter two compounds was attributed to their being banned in the mid 1970s. JF - Environmental Health Perspectives AU - Sjodin, Andreas AU - Jones, Richard S AU - Focant, Jean-Francois AU - Lapeza, Chester AU - Wang, Richard Y AU - McGahee, Ernest E AU - Zhang, Yalin Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 654 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - ETHERS KW - POLYCHLORINATED BIPHENYLS KW - BLOOD ANALYSIS KW - POLYBROMINATED BIPHENYLS KW - FLAME RETARDANTS KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14708618?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Retrospective+Time-Trend+Study+of+Polybrominated+Diphenyl+Ether+and+Polybrominated+and+Polychlorinated+Biphenyl+Levels+in+Human+Serum+from+the+United+States&rft.au=Sjodin%2C+Andreas%3BJones%2C+Richard+S%3BFocant%2C+Jean-Francois%3BLapeza%2C+Chester%3BWang%2C+Richard+Y%3BMcGahee%2C+Ernest+E%3BZhang%2C+Yalin&rft.aulast=Sjodin&rft.aufirst=Andreas&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=654&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ETHERS; POLYBROMINATED BIPHENYLS; POLYCHLORINATED BIPHENYLS; BLOOD ANALYSIS; FLAME RETARDANTS; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Early-Life Environmental Risk Factors for Asthma: Findings from the Children's Health Study AN - 14707866; 10662617 JF - Environmental Health Perspectives AU - Salam, Muhammad Towhid AU - Li, Yu-Fen AU - Langholz, Bryan AU - Gilliland, Frank Davis Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 760 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - COCKROACHES KW - RISK ASSESSMENT KW - PATHOLOGY, CHILDREN KW - DEMOGRAPHY KW - AIR POLLUTION, INDOOR KW - ASTHMA KW - PESTICIDE EXPOSURE KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707866?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Early-Life+Environmental+Risk+Factors+for+Asthma%3A+Findings+from+the+Children%27s+Health+Study&rft.au=Salam%2C+Muhammad+Towhid%3BLi%2C+Yu-Fen%3BLangholz%2C+Bryan%3BGilliland%2C+Frank+Davis&rft.aulast=Salam&rft.aufirst=Muhammad&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=760&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - RISK ASSESSMENT; PATHOLOGY, CHILDREN; DEMOGRAPHY; AIR POLLUTION, INDOOR; ASTHMA; COCKROACHES; PESTICIDE EXPOSURE ER - TY - JOUR T1 - Magnetic-Field-Induced DNA Strand Breaks in Brain Cells of the Rat AN - 14707811; 10662608 AB - Male SpragueDawley rats were exposed to a 60-Hz magnetic field at 0.1 mT for 24 or 48 h in the laboratory, and DNA strand breaks in brain cells were assessed. In addition, treatments with the vitamin E analog, Trolox, the nitric oxide synthase inhibitor, 7-nitroindazole, and the iron chelator, deferiprone, were performed. Magnetic exposure increased single- and double-strand breaks, and increasing the exposure duration from 24 to 48 h significantly increased cumulative single- and double-strand breaks. Treatment with Trolox blocked the effects of the magnetic field on DNA strand breaks, as did the deferiprone and 7-nitroindazole treatments, which suggested that the effects of magnetic fields, in terms of DNA strand breaks, were caused by free radicals, especially by an Fe-mediated free radical process. JF - Environmental Health Perspectives AU - Lai, Henry AU - Singh, Narendra P Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 687 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - NEUROTOXICITY KW - DNA KW - MUTAGENIC AGENTS KW - ELECTROMAGNETIC FIELDS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707811?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Magnetic-Field-Induced+DNA+Strand+Breaks+in+Brain+Cells+of+the+Rat&rft.au=Lai%2C+Henry%3BSingh%2C+Narendra+P&rft.aulast=Lai&rft.aufirst=Henry&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=687&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - NEUROTOXICITY; DNA; MUTAGENIC AGENTS; ELECTROMAGNETIC FIELDS ER - TY - JOUR T1 - Predictors of Personal Polycyclic Aromatic Hydrocarbon Exposures Among Pregnant Minority Women in New York City AN - 14707786; 10662616 AB - Airborne PAH personal exposures were studied in pregnant minority women in New York City, and questionnaire data were used to predict exposure. The data included race/ethnicity, socioeconomic status, medical history, lifetime residential history, and history of active and passive smoking, as well as occupational history, workplace exposures, and environmental exposures during pregnancy. Personal exposure data were collected for 344 subjects, and multiple linear regression analysis was employed to explore the roles of questionnaire variables as predictors of individual PAH concentrations as well as the sum of all compounds. Results showed that personal exposures ranged from 0.06 ng/m super(3) for dibenz[a,h]anthracene to 4.1 ng/m super(3) for pyrene, while the mean benzo[a]pyrene concentration was 0.5 ng/m super(3), and the mean total PAH concentration was 8.0 ng/m super(3). Season and a variety of indoor and outdoor sources of PAHs were found to influence the personal exposures, with the association found between total PAH and questionnaire variables driven largely by pyrene. JF - Environmental Health Perspectives AU - Tonne, Cathryn C AU - Whyatt, Robin M AU - Camann, David E AU - Perera, Frederica P AU - Kinney, Patrick L Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 754 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - DOSIMETRY KW - POLYCYCLIC AROMATIC HYDROCARBON KW - SOCIOECONOMICS KW - DEMOGRAPHY KW - AIR POLLUTION, INDOOR KW - SEASONAL COMPARISONS KW - NEW YORK CITY KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Predictors+of+Personal+Polycyclic+Aromatic+Hydrocarbon+Exposures+Among+Pregnant+Minority+Women+in+New+York+City&rft.au=Tonne%2C+Cathryn+C%3BWhyatt%2C+Robin+M%3BCamann%2C+David+E%3BPerera%2C+Frederica+P%3BKinney%2C+Patrick+L&rft.aulast=Tonne&rft.aufirst=Cathryn&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=754&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t Tables N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - DOSIMETRY; SOCIOECONOMICS; DEMOGRAPHY; AIR POLLUTION, INDOOR; SEASONAL COMPARISONS; NEW YORK CITY; POLYCYCLIC AROMATIC HYDROCARBON ER - TY - JOUR T1 - Phytoestrogen Signaling and Symbiotic Gene Activation Are Disrupted by Endocrine-Disrupting Chemicals AN - 14707752; 10662605 AB - Phytoestrogens act as specific attractants for symbiotic Rhizobium soil bacteria. Host specificity between plants and Rhizobium is regulated by the unique profile of phytoestrogens produced by the host plant, which are recognized by species-specific nodulation D (NodD) proteins within Rhizobium soil bacteria, with this NodDligand specificity regulating transcription of key nod genes. Using the wild-type Rhizobium strain, Sinorhizobium meliloti 1021 pRmM57, the effects of natural and synthetic chemicals on phytochemical signaling to NodD receptors were examined. The chemicals included PCBs, insecticides, 17 beta -estradiol, diethylstilbestrol, and phytochemicals. Results showed that environmentally relevant concentrations of 45 of the 62 endocrine-disrupting chemicals and organochlorine pesticides statistically significantly inhibited luteolin-NodD receptor signaling and symbiotic nod gene activation. Many of the compounds exhibited doseresponsive, concentration-dependent inhibition of luteolin-NodD-induced nod gene expression. JF - Environmental Health Perspectives AU - Fox, Jennifer E AU - Starcevic, Marta AU - Jones, Phillip E AU - Burow, Matthew E AU - McLachlan, John A Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 672 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BACTERIA KW - POLYCHLORINATED BIPHENYLS KW - HORMONAL EFFECTS KW - NITROGEN FIXATION KW - SYMBIOSIS KW - ORGANOCHLORINE PESTICIDES KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707752?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Phytoestrogen+Signaling+and+Symbiotic+Gene+Activation+Are+Disrupted+by+Endocrine-Disrupting+Chemicals&rft.au=Fox%2C+Jennifer+E%3BStarcevic%2C+Marta%3BJones%2C+Phillip+E%3BBurow%2C+Matthew+E%3BMcLachlan%2C+John+A&rft.aulast=Fox&rft.aufirst=Jennifer&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=672&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 3 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BACTERIA; POLYCHLORINATED BIPHENYLS; HORMONAL EFFECTS; SYMBIOSIS; NITROGEN FIXATION; ORGANOCHLORINE PESTICIDES ER - TY - JOUR T1 - Human Consumption of Methyleugenol and Its Elimination from Serum AN - 14707749; 10662606 AB - Methyleugenol occurs naturally in a number of exotic herbs and spices and is used commonly as a flavoring agent in foods. The levels of methyleugenol in human blood were measured at specific times before and after eating gingersnap cookies, known to contain the compound. The 20 study subjects fasted from midnight until the study commenced, and they were fed gingersnaps that contained approximately 3.3 mu g methyleugenol/g. The meal consisted of 12 cookies containing approximately 216 mu g methyleugenol. Blood was drawn for analysis prior to the meal and at 15, 30, 60, and 120 min after the meal. The median fasting level of methyleugenol in serum was 13 pg/g, and the median serum level at 15 min after the meal peaked at 54 pg/g, declining to 40 pg/g at 30 min, to 29 pg/g at 60 min, and to 20 pg/g at 120 min. JF - Environmental Health Perspectives AU - Schecter, Arnold AU - Lucier, George W AU - Cunningham, Michael L AU - Abdo, Kamal M AU - Blumenthal, Greg AU - Silver, Andrew G AU - Melnick, Ron Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 678 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD ANALYSIS KW - DISSIPATION RATES KW - CARCINOGENIC AGENTS KW - FOOD ADDITIVES KW - TEMPORAL COMPARISONS KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707749?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Human+Consumption+of+Methyleugenol+and+Its+Elimination+from+Serum&rft.au=Schecter%2C+Arnold%3BLucier%2C+George+W%3BCunningham%2C+Michael+L%3BAbdo%2C+Kamal+M%3BBlumenthal%2C+Greg%3BSilver%2C+Andrew+G%3BMelnick%2C+Ron&rft.aulast=Schecter&rft.aufirst=Arnold&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=678&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD ANALYSIS; DISSIPATION RATES; CARCINOGENIC AGENTS; FOOD ADDITIVES; TEMPORAL COMPARISONS ER - TY - JOUR T1 - Association Between Hemochromatosis Genotype and Lead Exposure Among Elderly Men: the Normative Aging Study AN - 14707116; 10662614 AB - Using a subsample of the Normative Aging Study established by the Veterans Administration in 1963 to assess lead biomarkers and chronic disease, elderly men were genotyped in terms of the C282Y and/or H63D hemochromatosis gene associated with body Pb burden. Bone Pb measurements were taken at the mid-tibial shaft and the patella, and blood Pb levels were measured. Of the 765 subjects, 730 were genotyped for H63D and C282Y. The overall trend in the bone and blood Pb levels was that carriers of the hemochromatosis gene variants had lower bone and blood Pb levels. Subjects with either one or two copies of either allele had lower bone or blood Pb levels, on average, than did wild-type subjects. The findings suggested that subjects with the hemochromatosis gene variants may have higher iron stores, on average, and lower Pb absorption because of the decreased risk of Fe deficiency. JF - Environmental Health Perspectives AU - Wright, Robert O AU - Silverman, Edwin K AU - Schwartz, Joel AU - Tsaih, Shring-Wern AU - Senter, Jody AU - Sparrow, David AU - Weiss, Scott T Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 746 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BLOOD LEAD LEVEL KW - BIOACCUMULATION, HUMAN KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707116?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Association+Between+Hemochromatosis+Genotype+and+Lead+Exposure+Among+Elderly+Men%3A+the+Normative+Aging+Study&rft.au=Wright%2C+Robert+O%3BSilverman%2C+Edwin+K%3BSchwartz%2C+Joel%3BTsaih%2C+Shring-Wern%3BSenter%2C+Jody%3BSparrow%2C+David%3BWeiss%2C+Scott+T&rft.aulast=Wright&rft.aufirst=Robert&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=746&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 4 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - BLOOD LEAD LEVEL; GENETICS, HUMAN; BIOACCUMULATION, HUMAN ER - TY - JOUR T1 - Maternal Stress Modulates the Effects of Developmental Lead Exposure AN - 14707078; 10662612 AB - To examine the possible interaction between maternal stress and lead exposure on behavioral and neurochemical development in offspring, male and female Long-Evans rats were used involving four experimental groups of dams: no maternal stress; no Pb exposure; no maternal stress, Pb exposure; and maternal stress plus Pb exposure. Maternal stress involved constraint on gestation days 16 and 17, and the Pb exposure concentration was 150 ppm in drinking water. Long-term behavioral effects in offspring were assessed using a fixed-interval schedule of food reinforcement, which was preceded by locomotor activity testing in both sexes when male offspring were 60 d old and females were 80100 d old. Results showed that Pb exposure and stress interacted. Not only did the consequences of preweaning Pb alone, maternal stress alone, and their combination differ markedly by sex, but each had permanent consequences for offspring that manifested variously as changes in neurochemical measures, corticosteroid systems, and/or behavior. The effects of Pb exposure were more prominent than those of stress in male offspring, whereas in female offspring, the impact of prenatal stress predominated in the behavioral effects. JF - Environmental Health Perspectives AU - Cory-Slechta, Deborah A AU - Virgolini, Miriam B AU - Thiruchelvam, Mona AU - Weston, Doug D AU - Bauter, Mark R Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 717 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - SEX COMPARISONS KW - PSYCHOLOGICAL EFFECTS KW - NEUROTOXICITY KW - BEHAVIOR KW - REPRODUCTION, ANIMAL KW - LEAD KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707078?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Maternal+Stress+Modulates+the+Effects+of+Developmental+Lead+Exposure&rft.au=Cory-Slechta%2C+Deborah+A%3BVirgolini%2C+Miriam+B%3BThiruchelvam%2C+Mona%3BWeston%2C+Doug+D%3BBauter%2C+Mark+R&rft.aulast=Cory-Slechta&rft.aufirst=Deborah&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=717&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - SEX COMPARISONS; NEUROTOXICITY; PSYCHOLOGICAL EFFECTS; BEHAVIOR; LEAD; REPRODUCTION, ANIMAL ER - TY - JOUR T1 - Chemical Communication Threatened by Endocrine-Disrupting Chemicals AN - 14707025; 10662601 AB - The evolution of communication via hormone signaling may be one of the oldest and most crucial links shared between all organisms. For chemical communication to occur, a receptor must have affinity for specific chemical ligands or signals, and the recognition must initiate a response. A number of natural and synthetic chemicals exist in the environment, however, which mimic hormones and disrupt endocrine signaling in vertebrates through interaction with various nuclear receptors and signal transducer proteins. The mechanism of action is defined by vertebrate estrogen receptors (ERs), which bind phytoestrogen ligands, endogenous ligands, and endocrine-disrupting chemicals with specific affinity. Nodulation D protein (NodD) receptors in Rhizobium soil bacteria recognize phytoestrogens as recruitment signals to initiate nitrogen-fixing symbiosis. Although they share no common evolutionary ancestor, NodD and ER recognize and respond to a similar profile of chemical signals found in the environment. It is argued here that both of the signaling systems are vulnerable to disruption by endocrine-disrupting chemicals present in their shared environment. This disruption is described, citing data from a number of studies, and the implications of the disruption are discussed. JF - Environmental Health Perspectives AU - Fox, Jennifer E Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 648 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HORMONAL EFFECTS KW - CHEMICAL CONTAMINATION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14707025?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Chemical+Communication+Threatened+by+Endocrine-Disrupting+Chemicals&rft.au=Fox%2C+Jennifer+E&rft.aulast=Fox&rft.aufirst=Jennifer&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=648&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - HORMONAL EFFECTS; CHEMICAL CONTAMINATION ER - TY - JOUR T1 - Synergistic Interaction in Simultaneous Exposure to Streptomyces californicus and Stachybotrys chartarum AN - 14704729; 10662603 AB - Mouse RAW264.7 macrophages were exposed simultaneously to the gram-positive bacterium, Streptomyces californicus, and to Aspergillus versicolor, Penicillium spinulosum, Stachybotrys chartarum, Bacillus cereus, Mycobacterium terrae, or Pseudomonas fluorescens, and their interaction was examined. In addition, known mycotoxins were tested for their inflammatory and cytotoxic potency alone and together with S. californicus. Results showed that only S. chartarum was able to potentiate the inflammatory effect of S. californicus, and among the metabolites produced typically by S. chartarum, there was at least one compound, trichodermin, that produced a similar synergistic effect along with a closely related compound, 7- alpha -hydroxytrichodermol. Exposure to S. californicus induced the nuclear binding activity of nuclear factor-B. While spores of S. chartarum alone were not able to evoke any inflammatory responses in macrophages, they triggered a significant, dose-dependent cytokine response in cells when exposed in conjunction with a low dose of S. californicus. JF - Environmental Health Perspectives AU - Huttunen, Kati AU - Pelkonen, Jukka AU - Nielsen, Kristian Fogg AU - Nuutinen, Ulla AU - Jussila, Juha AU - Hirvonen, Maija-Riitta Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 659 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 6 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - BACTERIA KW - CYTOTOXICITY KW - SYNERGISTIC EFFECTS KW - IMMUNE RESPONSE KW - FUNGI KW - MYCOTOXINS KW - AIR POLLUTION, INDOOR KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14704729?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Synergistic+Interaction+in+Simultaneous+Exposure+to+Streptomyces+californicus+and+Stachybotrys+chartarum&rft.au=Huttunen%2C+Kati%3BPelkonen%2C+Jukka%3BNielsen%2C+Kristian+Fogg%3BNuutinen%2C+Ulla%3BJussila%2C+Juha%3BHirvonen%2C+Maija-Riitta&rft.aulast=Huttunen&rft.aufirst=Kati&rft.date=2004-05-01&rft.volume=112&rft.issue=6&rft.spage=659&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 1 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - FUNGI; BACTERIA; CYTOTOXICITY; AIR POLLUTION, INDOOR; MYCOTOXINS; SYNERGISTIC EFFECTS; IMMUNE RESPONSE ER - TY - JOUR T1 - Inhibition of Ape1 Nuclease Activity by Lead, Iron, and Cadmium AN - 14699284; 10662929 AB - Reduced DNA repair capacity can lead to genetic instability and human disease, and studies have suggested that environmental metals are co-mutagenic, potentiating the carcinogenic effects of DNA-damaging agents by inhibiting DNA repair processes. Apurinic/apyrimidinic (AP) sites are frequent lesions in DNA, generated by spontaneous, damage-induced, or enzyme-catalyzed hydrolysis of the N-glycosylic bond. If unrepaired, these noncoding lesions present both cytotoxic and mutagenic challenges to the cell, with AP endonuclease 1 (Ape1) the major mammalian abasic endonuclease, accounting for greater than 95% of the total cellular AP site incision activity. Results are presented from a study in which the effects of divalent lead, iron, and cadmium on Ape1 nuclease activity were examined using a 26-mer oligonucleotide duplex containing a single, centrally located abasic site analog. Results show that all three metals specifically inhibited AP endonuclease activity in whole-cell extracts but did not dramatically affect other steps of repair. JF - Environmental Health Perspectives AU - McNeill, Daniel R AU - Narayana, Avinash AU - Wong, Heng-Kuan AU - Wilson, David M Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 799 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - CADMIUM KW - CARCINOGENIC MECHANISMS KW - DNA KW - LEAD KW - MUTAGENIC AGENTS KW - IRON KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14699284?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Inhibition+of+Ape1+Nuclease+Activity+by+Lead%2C+Iron%2C+and+Cadmium&rft.au=McNeill%2C+Daniel+R%3BNarayana%2C+Avinash%3BWong%2C+Heng-Kuan%3BWilson%2C+David+M&rft.aulast=McNeill&rft.aufirst=Daniel&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=799&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 5 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - CARCINOGENIC MECHANISMS; DNA; LEAD; CADMIUM; MUTAGENIC AGENTS; IRON ER - TY - JOUR T1 - Metal Particulate Matter Components Affect Gene Expression and Beat Frequency of Neonatal Rat Ventricular Myocytes AN - 14695291; 10662928 AB - Ventricular myocytes were isolated from 1-d-old SpragueDawley rats, and the cytotoxicity produced by exposure to various concentrations of zinc and vanadium was assessed. Measurements of spontaneous beat rate were also conducted on the cells, as were reverse transcription and quantitative real-time polymerase chain reaction. Results revealed that both Zn and V modulated the function of cardiac myocytes by slowing their spontaneous beat rate, analogous to slowing of the heart rate demonstrated previously in rats instilled with residual oil flyash containing high levels of the metals. The decrease induced by Zn, however, was significantly more pronounced than that induced by V, occurring at lower concentrations and shorter exposure times. Exposure to Zn for 24 h resulted in a greater increase in the accumulation of mRNAs coding for interleukin-6 and heat shock protein 70 than that observed after exposure for 6 h, and marked changes in gene expression of several ion channel and gap junction proteins were also observed. JF - Environmental Health Perspectives AU - Graff, Donald W AU - Cascio, Wayne E AU - Brackhan, Joseph A AU - Devlin, Robert B Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 792 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - AIR POLLUTION EFFECTS KW - CYTOTOXICITY KW - CARDIOVASCULAR EFFECTS KW - RATS KW - PARTICULATES KW - ZINC KW - DOSE RESPONSE PROFILES KW - VANADIUM KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14695291?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Metal+Particulate+Matter+Components+Affect+Gene+Expression+and+Beat+Frequency+of+Neonatal+Rat+Ventricular+Myocytes&rft.au=Graff%2C+Donald+W%3BCascio%2C+Wayne+E%3BBrackhan%2C+Joseph+A%3BDevlin%2C+Robert+B&rft.aulast=Graff&rft.aufirst=Donald&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=792&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 11 |t graphs N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - ZINC; AIR POLLUTION EFFECTS; DOSE RESPONSE PROFILES; CYTOTOXICITY; CARDIOVASCULAR EFFECTS; VANADIUM; RATS; PARTICULATES ER - TY - JOUR T1 - Using a Customized DNA Microarray for Expression Profiling of the Estrogen-Responsive Genes to Evaluate Estrogen Activity Among Natural Estrogens and Industrial Chemicals AN - 14694608; 10662926 JF - Environmental Health Perspectives AU - Terasaka, Shunichi AU - Aita, Yukie AU - Inoue, Akio AU - Hayashi, Shinichi AU - Nishigaki, Michiko AU - Aoyagi, Kazuhiko AU - Sasaki, Hiroki Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 773 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - MEASUREMENTS AND SENSING KW - DNA KW - HORMONAL EFFECTS KW - GENETICS, HUMAN KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694608?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Using+a+Customized+DNA+Microarray+for+Expression+Profiling+of+the+Estrogen-Responsive+Genes+to+Evaluate+Estrogen+Activity+Among+Natural+Estrogens+and+Industrial+Chemicals&rft.au=Terasaka%2C+Shunichi%3BAita%2C+Yukie%3BInoue%2C+Akio%3BHayashi%2C+Shinichi%3BNishigaki%2C+Michiko%3BAoyagi%2C+Kazuhiko%3BSasaki%2C+Hiroki&rft.aulast=Terasaka&rft.aufirst=Shunichi&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=773&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - MEASUREMENTS AND SENSING; HORMONAL EFFECTS; DNA; GENETICS, HUMAN ER - TY - JOUR T1 - Toxicogenomics of Subchronic Hexachlorobenzene Exposure in Brown Norway Rats AN - 14694103; 10662927 AB - DNA microarray analysis was used to assess changes associated with hexachlorobenzene exposure in Brown Norway rats at the gene expression level. The rats were exposed to 0, 150, or 450 mg hexachlorobenzene/kg diet, and gene expression levels were assessed in spleen, mesenteric lymph nodes, thymus, blood, liver, and kidney. Previously observed effects of hexachlorobenzene exposure were noted, including stimulatory effects on the immune system and induction of enzymes involved in drug metabolism, porphyria, and the reproductive system, but several novel effects were also discerned, including upregulation of genes encoding proinflammatory cytokines, antioxidants, acute phase proteins, complement, mast cell markers, chemokines, and cell adhesion molecules. The gene expression profiles provided evidence for the importance of macrophages and granulocytes and mediators released by these cells in the adverse inflammatory response against hexachlorobenzene. JF - Environmental Health Perspectives AU - Ezendam, Janine AU - Staedtler, Frank AU - Pennings, Jeroen AU - Vandebriel, Rob J AU - Pieters, Raymond AU - Harleman, Johannes H AU - Vos, Joseph G Y1 - 2004/05// PY - 2004 DA - May 2004 SP - 782 PB - US Government Printing Office, Superintendent of Documents, P.O. Box 371954 Pittsburgh PA 15250-7954 VL - 112 IS - 7 SN - 0091-6765, 0091-6765 KW - Environment Abstracts KW - HEXACHLOROBENZENE KW - RATS KW - IMMUNOTOXICITY KW - GENETICS, ANIMAL KW - DOSE RESPONSE PROFILES KW - DNA KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/14694103?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Toxicogenomics+of+Subchronic+Hexachlorobenzene+Exposure+in+Brown+Norway+Rats&rft.au=Ezendam%2C+Janine%3BStaedtler%2C+Frank%3BPennings%2C+Jeroen%3BVandebriel%2C+Rob+J%3BPieters%2C+Raymond%3BHarleman%2C+Johannes+H%3BVos%2C+Joseph+G&rft.aulast=Ezendam&rft.aufirst=Janine&rft.date=2004-05-01&rft.volume=112&rft.issue=7&rft.spage=782&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Document feature - |n 2 |t diagrams N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - IMMUNOTOXICITY; GENETICS, ANIMAL; DOSE RESPONSE PROFILES; DNA; HEXACHLOROBENZENE; RATS ER - TY - JOUR T1 - Arsenic removal from aqueous solution via ferrihydrite crystallization control. AN - 71880332; 15116842 AB - Removal of arsenate anion from aqueous solution by coprecipitation with ferrihydrite has been studied under conditions in which the Fe/As ratio is maintained at a constant level, while the degree of supersaturation with respect to the iron oxide precipitate is varied. An Fe/As ratio of 12 was chosen, and supersaturation was controlled by varying the iron concentration or the pH. The relationship between supersaturation and arsenic removal was found to follow an exponential curve, with greater arsenic removal occurring at higher supersaturation ratios for each of the pH values tested. Higher supersaturation ratios were required to achieve a given level of arsenic removal at pH 7 than would be required to achieve the same level of removal at pH 3.5. The results provide important guidelines for selection of appropriate concentrations of iron(III) required for arsenic removal under various circumstances. Powder XRD analysis of the arsenate-ferrihydrite precipitates showed an increasing degree of structural order with decreasing levels of supersaturation. TEM images of the precipitates revealed that aggregates with a morphology similar to that of schwertmannite are formed in some samples at low supersaturation levels. The results described in this paper indicate that the overall efficiency of arsenic removal involves a combination of both supersaturation and pH effects, with pH controlling the affinity of arsenate for the ferrihydrite surface, and supersaturation controlling the surface area and physical properties of the ferrihydrite product. JF - Environmental science & technology AU - Richmond, William R AU - Loan, Mitch AU - Morton, Jonathon AU - Parkinson, Gordon M AD - Nanochemistry Research Institute and A. J. Parker CRC for Hydrometallurgy, Curtin University of Technology, GPO Box U 1987, Perth, 6845, Australia. bill@power.curtin.edu.au Y1 - 2004/04/15/ PY - 2004 DA - 2004 Apr 15 SP - 2368 EP - 2372 VL - 38 IS - 8 SN - 0013-936X, 0013-936X KW - Ferric Compounds KW - 0 KW - Water Pollutants KW - ferric oxyhydroxide KW - 87PZU03K0K KW - Ferritins KW - 9007-73-2 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Crystallization KW - Hydrogen-Ion Concentration KW - Chemical Precipitation KW - Ferritins -- chemistry KW - Water Purification -- methods KW - Water Pollutants -- isolation & purification KW - Arsenic -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71880332?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Arsenic+removal+from+aqueous+solution+via+ferrihydrite+crystallization+control.&rft.au=Richmond%2C+William+R%3BLoan%2C+Mitch%3BMorton%2C+Jonathon%3BParkinson%2C+Gordon+M&rft.aulast=Richmond&rft.aufirst=William&rft.date=2004-04-15&rft.volume=38&rft.issue=8&rft.spage=2368&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-07-13 N1 - Date created - 2004-04-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The effect of abrupt osmotic shifts on the lag phase duration of physiologically distinct populations of Salmonella typhimurium. AN - 71865625; 15109788 AB - Relative lag time (RLT), i.e. lag time divided by generation time, was used to characterise the lag phase response of exponential and stationary phase Salmonella typhimurium subjected to NaCl-mediated hyperosmotic shifts. Abrupt hyperosmotic shifts induced lag phases. The RLT, however, varied with the physiological history of the inoculum and the magnitude of the shift. Turbidimetric data showed that exponential phase cells had larger RLTs (up to approximately 8 units) than stationary phase cells (up to 2-4 units). Inocula containing exponential and stationary phase cells mixed in known proportions gave intermediate results. For viable count data, there was little difference in RLT between exponential and stationary phase cells. The RLT response determined turbidimetrically was reproducible for exponential phase cells, but less so for stationary phase cells. It is suggested that there may be a lower limit for resolution of RLT, in the range 0-2 units, and that this may account for the lack of reproducibility in RLTs of stationary phase cells. It is hypothesised that stationary phase cells have enhanced resistance to osmotic stress and are able to exploit new growth environments at low a(w) more rapidly than exponential phase cells, resulting in shorter lag phases. However, the data indicate that turbidimetry may not accurately describe the lag phase response of exponential phase cells subjected to large osmotic shifts. Viable count data is required to investigate this hypothesis further. JF - International journal of food microbiology AU - Mellefont, L A AU - McMeekin, T A AU - Ross, T AD - Centre for Food Safety and Quality, School of Agricultural Science, University of Tasmania, GPO Box 252-54, Hobart 7001, Tasmania, Australia. Lyndal.Mellefont@utas.edu.au Y1 - 2004/04/15/ PY - 2004 DA - 2004 Apr 15 SP - 111 EP - 120 VL - 92 IS - 2 SN - 0168-1605, 0168-1605 KW - Sodium Chloride KW - 451W47IQ8X KW - Index Medicus KW - Food Microbiology KW - Nephelometry and Turbidimetry KW - Colony Count, Microbial KW - Models, Biological KW - Osmosis KW - Salmonella typhimurium -- physiology KW - Salmonella typhimurium -- growth & development KW - Sodium Chloride -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71865625?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+food+microbiology&rft.atitle=The+effect+of+abrupt+osmotic+shifts+on+the+lag+phase+duration+of+physiologically+distinct+populations+of+Salmonella+typhimurium.&rft.au=Mellefont%2C+L+A%3BMcMeekin%2C+T+A%3BRoss%2C+T&rft.aulast=Mellefont&rft.aufirst=L&rft.date=2004-04-15&rft.volume=92&rft.issue=2&rft.spage=111&rft.isbn=&rft.btitle=&rft.title=International+journal+of+food+microbiology&rft.issn=01681605&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-08-19 N1 - Date created - 2004-04-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Photosynthetic pigments in 37 species (65 strains) of Haptophyta: implications for oceanography and chemotaxonomy AN - 17997697; 5930217 AB - The pigment compositions of 37 species (65 strains) of cultured haptophytes were analysed using improved HPLC methods. We distinguished 8 pigment types based on the distribution of 9 chlorophyll c (chl c) pigments and 5 fucoxanthin derivatives. All types contained chl c sub(2) and Mg-2,4-divinyl phaeoporphyrin a sub(5) monomethyl ester (MgDVP), fucoxanthin, diadinoxanthin and beta , beta -carotene. Pigment types were based on the following additional pigments: Type 1: chl c sub(1); Type 2: chl c sub(1) and chl c sub(2)-Pavlova gyrans-type; Type 3: chl c sub(1) and chl c sub(2)-monogalactosyl diacylglyceride ester (chl c sub(2)-MGDG [18:4/14:0]); Type 4: chl c sub(1), chl c sub(3) and non-polar chl c sub(1)-like; Type 5: chl c sub(1), chl c sub(3), chl c sub(2)-MGDG [18:4/14:0] and 4-keto-fucoxanthin; Type 6: chl c sub(3), monovinyl chl c sub(3) (MV-chl c sub(3)), chl c sub(2)-MGDG [18:4/14:0], 19'-hexanoyloxyfucoxanthin and its 4-keto derivative, and traces of 19'-butanoyloxyfucoxanthin; Type 7: similar to Type 6, minus MV-chl c sub(3) but with chl c sub(2)-MGDG [14:0/14:0] added; Type 8: similar to Type 6, minus MV-chl c sub(3) but with significant 19'-butanoyloxyfucoxanthin. Taxonomic associations ranged from single genera to multiple families - Type 1: Pavlovaceae, Isochrysidaceae and Pleurochrysidaceae; Type 2: Pavlovaceae; Type 3: Isochrysidaceae; Type 4: Prymnesium spp.; Type 5: Ochrosphaera spp.; Type 6: Noeelaerhabdaceae, notably Emiliania spp.; Type 7: Chrysochromulina spp.; Type 8: Phaeocystaceae, Prymnesiaceae and Isochrysidaceae. These pigment types showed a strong correlation with available phylogenetic trees, supporting a genetic basis for the pigment associations. The additional marker pigments offer oceanographers greater power for detecting haptophytes in mixed populations, while also distinguishing a greater proportion of them from diatoms. JF - Marine Ecology Progress Series AU - Zapata, M AU - Jeffrey, S W AU - Wright, S W AU - Rodriguez, F AU - Garrido, J L AU - Clementson, L AD - CSIRO Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, shirley.jeffrey@csiro.au Y1 - 2004/04/14/ PY - 2004 DA - 2004 Apr 14 SP - 83 EP - 102 VL - 270 SN - 0171-8630, 0171-8630 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts KW - High-performance liquid chromatography KW - Photosynthetic pigments KW - Taxonomy KW - Oceanography KW - Haptophyta KW - Algae KW - D 04627:Algae/lichens KW - K 03044:Algae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17997697?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Ecology+Progress+Series&rft.atitle=Photosynthetic+pigments+in+37+species+%2865+strains%29+of+Haptophyta%3A+implications+for+oceanography+and+chemotaxonomy&rft.au=Zapata%2C+M%3BJeffrey%2C+S+W%3BWright%2C+S+W%3BRodriguez%2C+F%3BGarrido%2C+J+L%3BClementson%2C+L&rft.aulast=Zapata&rft.aufirst=M&rft.date=2004-04-14&rft.volume=270&rft.issue=&rft.spage=83&rft.isbn=&rft.btitle=&rft.title=Marine+Ecology+Progress+Series&rft.issn=01718630&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Haptophyta; Photosynthetic pigments; Oceanography; High-performance liquid chromatography; Taxonomy; Algae ER - TY - JOUR T1 - Population genetic structure of the perlemoen Haliotis midae in South Africa: evidence of range expansion and founder events AN - 17981157; 5930223 AB - Genetic diversity in Haliotis midae, a highly valued and heavily exploited marine gastropod, was assessed using 3 marker types across samples from the species' range in South Africa. Variation was compared at 7 allozyme loci, 2 regions of mitochondrial DNA and 3 microsatellite loci. We conclude that populations of H. midae on either side of Cape Agulhas represent 2 independent reproductive stocks. The area of transition between the stocks coincides with oceanographic features of the region. Evidence from all 3 types of genetic marker indicates an isolated introduction event to the east of Cape Agulhas, and subsequent range expansion in an easterly direction. The disparity between allozyme data and the other 2 forms is seen as further evidence for the presence of balancing selection at allozyme loci. JF - Marine Ecology Progress Series AU - Evans, B S AU - Sweijd, NA AU - Bowie, RCK AU - Cook, P A AU - Elliott, NG AD - School of Zoology, University of Tasmania, GPO Box 252-05, Hobart, Tasmania 7001, Australia, brad.evans@jcu.edu.au Y1 - 2004/04/14/ PY - 2004 DA - 2004 Apr 14 SP - 163 EP - 172 VL - 270 SN - 0171-8630, 0171-8630 KW - Ecology Abstracts KW - Population genetics KW - Haliotis midae KW - South Africa KW - Genetic structure KW - D 04658:Molluscs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17981157?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Ecology+Progress+Series&rft.atitle=Population+genetic+structure+of+the+perlemoen+Haliotis+midae+in+South+Africa%3A+evidence+of+range+expansion+and+founder+events&rft.au=Evans%2C+B+S%3BSweijd%2C+NA%3BBowie%2C+RCK%3BCook%2C+P+A%3BElliott%2C+NG&rft.aulast=Evans&rft.aufirst=B&rft.date=2004-04-14&rft.volume=270&rft.issue=&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Marine+Ecology+Progress+Series&rft.issn=01718630&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Haliotis midae; South Africa; Population genetics; Genetic structure ER - TY - JOUR T1 - A novel secreted protein toxin from the insect pathogenic bacterium Xenorhabdus nematophila. AN - 71806897; 14707137 AB - The bacterium Xenorhabdus nematophila is an insect pathogen that produces several proteins that enable it to kill insects. Screening of a cosmid library constructed from X. nematophila strain A24 identified a gene that encoded a novel protein that was toxic to insects. The 42-kDa protein encoded by the toxin gene was expressed and purified from a recombinant system, and was shown to kill the larvae of insects such as Galleria mellonella and Helicoverpa armigera when injected at doses of around 30-40 ng/g larvae. Sequencing and bioinformatic analysis suggested that the toxin was a novel protein, and that it was likely to be part of a genomic island involved in pathogenicity. When the native bacteria were grown under laboratory conditions, a soluble form of the 42-kDa toxin was secreted only by bacteria in the phase II state. Preliminary histological analysis of larvae injected with recombinant protein suggested that the toxin primarily acted on the midgut of the insect. Finally, some of the common strategies used by the bacterial pathogens of insects, animals, and plants are discussed. JF - The Journal of biological chemistry AU - Brown, Susan E AU - Cao, Anh T AU - Hines, Eric R AU - Akhurst, Raymond J AU - East, Peter D AD - CSIRO Entomology, GPO Box 1700, Acton, Australian Capital Territory 2601, Australia. sue.brown@csiro.au Y1 - 2004/04/09/ PY - 2004 DA - 2004 Apr 09 SP - 14595 EP - 14601 VL - 279 IS - 15 SN - 0021-9258, 0021-9258 KW - Recombinant Proteins KW - 0 KW - Toxins, Biological KW - Index Medicus KW - Software KW - Animals KW - Escherichia coli -- metabolism KW - Dose-Response Relationship, Drug KW - Electrophoresis, Polyacrylamide Gel KW - Biological Assay KW - Amino Acid Sequence KW - Cosmids KW - Photorhabdus -- metabolism KW - Base Sequence KW - Blotting, Western KW - Larva -- microbiology KW - Molecular Sequence Data KW - Recombinant Proteins -- chemistry KW - Time Factors KW - Gene Library KW - Xenorhabdus -- metabolism KW - Toxins, Biological -- chemistry KW - Insects -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71806897?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+biological+chemistry&rft.atitle=A+novel+secreted+protein+toxin+from+the+insect+pathogenic+bacterium+Xenorhabdus+nematophila.&rft.au=Brown%2C+Susan+E%3BCao%2C+Anh+T%3BHines%2C+Eric+R%3BAkhurst%2C+Raymond+J%3BEast%2C+Peter+D&rft.aulast=Brown&rft.aufirst=Susan&rft.date=2004-04-09&rft.volume=279&rft.issue=15&rft.spage=14595&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+biological+chemistry&rft.issn=00219258&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-01 N1 - Date created - 2004-04-06 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: J Biol Chem. 2011 Oct 14;286(41):36161 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Stress, colon cancer and workers' compensation. AN - 71798512; 15059056 JF - The Medical journal of Australia AU - Nisselle, Paul AD - Medical Panels, GPO Box 2709X, Melbourne, Victoria 3001, Australia. nisselp@ozemail.com.au Y1 - 2004/04/05/ PY - 2004 DA - 2004 Apr 05 SP - 341 EP - 342 VL - 180 IS - 7 SN - 0025-729X, 0025-729X KW - Index Medicus KW - Probability KW - Prisons KW - Workload -- psychology KW - Risk Factors KW - Humans KW - Middle Aged KW - South Australia KW - Male KW - Expert Testimony -- legislation & jurisprudence KW - Workers' Compensation -- legislation & jurisprudence KW - Occupational Diseases -- psychology KW - Colorectal Neoplasms -- psychology KW - Stress, Psychological -- complications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71798512?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Medical+journal+of+Australia&rft.atitle=Stress%2C+colon+cancer+and+workers%27+compensation.&rft.au=Nisselle%2C+Paul&rft.aulast=Nisselle&rft.aufirst=Paul&rft.date=2004-04-05&rft.volume=180&rft.issue=7&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=The+Medical+journal+of+Australia&rft.issn=0025729X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-05-17 N1 - Date created - 2004-04-02 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment On: Med J Aust. 2004 Apr 5;180(7):339-40 [15059055] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hydrolysis of organophosphorus insecticides by in vitro modified carboxylesterase E3 from Lucilia cuprina. AN - 71769558; 15041019 AB - Resistance of the blowfly, Lucilia cuprina, to organophosphorus (OP) insecticides is due to mutations in LcalphaE7, the gene encoding carboxylesterase E3, that enhance the enzyme's ability to hydrolyse insecticides. Two mutations occur naturally, G137D in the oxyanion hole of the esterase, and W251L in the acyl binding pocket. Previous in vitro mutagenesis and expression of these modifications to the cloned gene have confirmed their functional significance. G137D enhances hydrolysis of diethyl and dimethyl phosphates by 55- and 33-fold, respectively. W251L increases dimethyl phosphate hydrolysis similarly, but only 10-fold for the diethyl homolog; unlike G137D however, it also retains ability to hydrolyse carboxylesters in the leaving group of malathion (malathion carboxylesterase, MCE), conferring strong resistance to this compound. In the present work, we substituted these and nearby amino acids by others expected to affect the efficiency of the enzyme. Changing G137 to glutamate or histidine was less effective than aspartate in improving OP hydrolase activity and like G137D, it diminished MCE activity, primarily through increases in Km. Various substitutions of W251 to other smaller residues had a broadly similar effect to W251L on OP hydrolase and MCE activities, but at least two were quantitatively better in kinetic parameters relating to malathion resistance. One, W251G, which occurs naturally in a malathion resistant hymenopterous parasitoid, improved MCE activity more than 20-fold. Mutations at other sites near the bottom of the catalytic cleft generally diminished OP hydrolase and MCE activities but one, F309L, also yielded some improvements in OP hydrolase activities. The results are discussed in relation to likely steric effects on enzyme-substrate interactions and future evolution of this gene. JF - Insect biochemistry and molecular biology AU - Heidari, R AU - Devonshire, A L AU - Campbell, B E AU - Bell, K L AU - Dorrian, S J AU - Oakeshott, J G AU - Russell, R J AD - CSIRO Entomology, GPO Box 1700, Canberra, ACT 2601, Australia. Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 353 EP - 363 VL - 34 IS - 4 SN - 0965-1748, 0965-1748 KW - Anions KW - 0 KW - Insecticides KW - Isoenzymes KW - Naphthalenes KW - Carboxylesterase KW - EC 3.1.1.1 KW - Acetylcholinesterase KW - EC 3.1.1.7 KW - Malathion KW - U5N7SU872W KW - Index Medicus KW - Isoenzymes -- chemistry KW - Animals KW - Naphthalenes -- chemistry KW - Torpedo KW - Humans KW - Anions -- chemistry KW - Amino Acid Sequence KW - Anions -- metabolism KW - Isoenzymes -- genetics KW - Drosophila melanogaster -- enzymology KW - Hydrolysis KW - Isoenzymes -- metabolism KW - Binding Sites KW - Mutagenesis, Site-Directed KW - Naphthalenes -- metabolism KW - Malathion -- chemistry KW - Conserved Sequence KW - Kinetics KW - Acetylcholinesterase -- genetics KW - Spodoptera -- cytology KW - Amino Acid Substitution KW - Cell Line KW - Malathion -- metabolism KW - Insecticides -- metabolism KW - Diptera -- enzymology KW - Diptera -- genetics KW - Carboxylesterase -- genetics KW - Insecticides -- chemistry KW - Carboxylesterase -- metabolism KW - Carboxylesterase -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71769558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Insect+biochemistry+and+molecular+biology&rft.atitle=Hydrolysis+of+organophosphorus+insecticides+by+in+vitro+modified+carboxylesterase+E3+from+Lucilia+cuprina.&rft.au=Heidari%2C+R%3BDevonshire%2C+A+L%3BCampbell%2C+B+E%3BBell%2C+K+L%3BDorrian%2C+S+J%3BOakeshott%2C+J+G%3BRussell%2C+R+J&rft.aulast=Heidari&rft.aufirst=R&rft.date=2004-04-01&rft.volume=34&rft.issue=4&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Insect+biochemistry+and+molecular+biology&rft.issn=09651748&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-06-15 N1 - Date created - 2004-03-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effect of external stresses on protein conformation: a computer modelling study. AN - 71759068; 14574523 AB - The increasing use of digital technologies such as mobile phones has led to major health concerns about the effects of non-ionizing pulsed radiation exposure. We believe that the health implications of exposure to radiation cannot be fully understood without establishing the molecular mechanisms of biological effects of pulsed microwaves. We aim to establish methods for studying the molecular mechanisms of protein structural and energetic changes occurring due to external stresses related to non-ionizing radiation by using a combination of experimental and theoretical approaches. In this paper, we present the results from our fully atomistic simulation study of chemical and thermal stress response of a prototype protein, insulin. We performed a series of molecular dynamics simulations of insulin in solution under equilibrium conditions, under chemical stress (imitated by reducing the disulfide bonds in the protein molecule), and under short-lived thermal stress (imitated by increasing simulation temperature for up to 2 ns). The resultant protein conformational behaviour was analysed for various properties with the aim of establishing analysis routines for classification of protein unfolding pathways and associated molecular mechanisms. JF - European biophysics journal : EBJ AU - Budi, A AU - Legge, S AU - Treutlein, H AU - Yarovsky, I AD - Department of Applied Physics, RMIT University, GPO Box 2476V, 3001 Melbourne, Victoria, Australia. Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 121 EP - 129 VL - 33 IS - 2 SN - 0175-7571, 0175-7571 KW - Insulin KW - 0 KW - Proteins KW - Index Medicus KW - Software KW - Proteins -- chemistry KW - Computer Simulation KW - Algorithms KW - Dose-Response Relationship, Radiation KW - Proteins -- radiation effects KW - Hot Temperature KW - Models, Molecular KW - Radiation, Nonionizing KW - Insulin -- radiation effects KW - Protein Conformation -- radiation effects KW - Insulin -- chemistry KW - Models, Chemical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71759068?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+biophysics+journal+%3A+EBJ&rft.atitle=Effect+of+external+stresses+on+protein+conformation%3A+a+computer+modelling+study.&rft.au=Budi%2C+A%3BLegge%2C+S%3BTreutlein%2C+H%3BYarovsky%2C+I&rft.aulast=Budi&rft.aufirst=A&rft.date=2004-04-01&rft.volume=33&rft.issue=2&rft.spage=121&rft.isbn=&rft.btitle=&rft.title=European+biophysics+journal+%3A+EBJ&rft.issn=01757571&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2005-02-15 N1 - Date created - 2004-03-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Calcineurin and heat-shock proteins modulation in clenbuterol-induced hypertrophied rat skeletal muscles. AN - 71736155; 14758479 AB - To examine the changes in heat shock proteins (HSPs) and calcineurin (CaN), a calcium/calmodulin regulated protein phosphatase, in hypertrophied rat skeletal muscles, adult male Wistar rats were administered clenbuterol (CLB, 30 mg l(-1) in drinking water), a beta 2-agonist, for 4 weeks. Compared to controls, CLB-treated rats had significantly larger body (10%) and relative (to body weight) soleus (Sol, 16%), plantaris (Plt, 32%) and gastrocnemius (Gast, 27%) weights. Immunohistochemically classified fast fibers were hypertrophied in the Sol (64%), Plt (62%), and deep (d, 70%) and superficial (s, 44%) regions of the Gast, whereas slow fibers were hypertrophied only in the Plt (47%). The percentage of fast fibers in the Sol increased from 10% to 21%. The myosin heavy chain (MHC) isoform composition shifted from slow to fast in the Sol (increase in the percentage of type IIa MHC and de novo synthesis of type IIx MHC) and Gast-d (de novo synthesis of type IIb MHC) and to the faster isoforms in the Plt (increase in the percentage of type IIb MHC). Hsp72 and Hsp90 levels in CLB-treated rats were 52% and 50% lower in the Sol and 44 and 41% lower in the Gast-d, respectively, than in control rats. In control rats, the relative content of CaN was: Sol>Gast-d>Plt>Gast-s, and CLB treatment enhanced the CaN content by 1.4-, 1.2-, 5.0-, and 3.3-fold, respectively. These results indicate that the down-regulation of HSPs in the Sol and Gast-d was closely related to a decrease in the slow phenotype, and that the relative up-regulation of CaN among the muscles/regions was closely related to the selective hypertrophy of fast fibers in the CLB-treated rats. JF - Pflugers Archiv : European journal of physiology AU - Oishi, Yasu AU - Imoto, Kohjiro AU - Ogata, Tomonori AU - Taniguchi, Kouhachi AU - Matsumoto, Hisahiro AU - Fukuoka, Yoshiyuki AU - Roy, Roland R AD - Laboratory of Muscle Physiology, Faculty of Education, Kumamoto University, 860-8555 Kumamoto, Japan. oishi@gpo.kumamoto-u.ac.jp Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 114 EP - 122 VL - 448 IS - 1 SN - 0031-6768, 0031-6768 KW - Adrenergic beta-Agonists KW - 0 KW - Heat-Shock Proteins KW - Calcineurin KW - EC 3.1.3.16 KW - Phosphoprotein Phosphatases KW - Myosin Heavy Chains KW - EC 3.6.4.1 KW - Clenbuterol KW - XTZ6AXU7KN KW - Index Medicus KW - Rats KW - Animals KW - Blotting, Western KW - Electrophoresis, Polyacrylamide Gel KW - Drinking -- physiology KW - Rats, Wistar KW - Phosphoprotein Phosphatases -- metabolism KW - Hypertrophy -- metabolism KW - Hypertrophy -- chemically induced KW - Myosin Heavy Chains -- metabolism KW - Immunohistochemistry KW - Male KW - Heat-Shock Proteins -- metabolism KW - Muscle, Skeletal -- pathology KW - Calcineurin -- metabolism KW - Clenbuterol -- toxicity KW - Adrenergic beta-Agonists -- toxicity KW - Muscle, Skeletal -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71736155?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pflugers+Archiv+%3A+European+journal+of+physiology&rft.atitle=Calcineurin+and+heat-shock+proteins+modulation+in+clenbuterol-induced+hypertrophied+rat+skeletal+muscles.&rft.au=Oishi%2C+Yasu%3BImoto%2C+Kohjiro%3BOgata%2C+Tomonori%3BTaniguchi%2C+Kouhachi%3BMatsumoto%2C+Hisahiro%3BFukuoka%2C+Yoshiyuki%3BRoy%2C+Roland+R&rft.aulast=Oishi&rft.aufirst=Yasu&rft.date=2004-04-01&rft.volume=448&rft.issue=1&rft.spage=114&rft.isbn=&rft.btitle=&rft.title=Pflugers+Archiv+%3A+European+journal+of+physiology&rft.issn=00316768&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2004-12-07 N1 - Date created - 2004-03-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Humanitarian Crises in Ethiopia and Eritrea AN - 60676148; 200422374 AB - Following some details on the scope of the humanitarian crisis in Ethiopia & Eritrea, factors that contribute to its recurrence are considered. Drought, ensuing famine, & war are key causes that are underpinned by high population growth, heavy debt burdens, resource scarcity, economic mismanagement, poor governance, misplaced budgetary priorities, poor agricultural policies, abject poverty, poor infrastructure, lack of access to fertilizers & pesticides, & armed conflict. J. Zendejas JF - Mediterranean Quarterly AU - Dagne, Theodros AD - Congressional Research Service Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 38 EP - 46 VL - 15 IS - 2 SN - 1047-4552, 1047-4552 KW - Political Factors KW - Famine KW - Foreign Aid KW - Ethiopia KW - Economic Conditions KW - Crises KW - Natural Disasters KW - Eritrea KW - article KW - 9085: government/political systems; national governments/political systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60676148?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mediterranean+Quarterly&rft.atitle=Humanitarian+Crises+in+Ethiopia+and+Eritrea&rft.au=Dagne%2C+Theodros&rft.aulast=Dagne&rft.aufirst=Theodros&rft.date=2004-04-01&rft.volume=15&rft.issue=2&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Mediterranean+Quarterly&rft.issn=10474552&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Ethiopia; Eritrea; Crises; Famine; Natural Disasters; Foreign Aid; Economic Conditions; Political Factors ER - TY - JOUR T1 - Investigations into the pyrolytic behaviour of coal/biomass blends using thermogravimetric analysis AN - 20729409; 5793461 AB - Investigations into the pyrolytic behaviour during co-pyrolysis of coal, biomass materials and coal/biomass blends prepared at different ratios (10:90, 20:80, 30:70 and 50:50) have been conducted using a thermogravimetric analysis (TGA) apparatus. The coal sample selected was Collie sub-bituminous coal from Western Australia, while wood waste (WW) and wheat straw (WS) were used as biomass samples. Three thermal events were identified during the pyrolysis. The first two were dominated by the biomass pyrolysis, while the third was linked to the coal pyrolysis, which occurred at much higher temperatures. No interactions were seen between the coal and biomass during co-pyrolysis. The pyrolytic characteristics of the blends followed those of the parent fuels in an additive manner. Among the tested blends, 20:80 blends showed the lowest activation energies of 90.9 and 78.7 kJ mol super(-1) for coal/WW and coal/WS blends respectively. The optimum blend ratio for pyrolysis of coal/WS was 50:50 with a high degradation rate in all the thermal events and a higher mass loss over the course of the co-pyrolysis compared to coal/WW blends examined. The reaction orders in these experiments were in the range of 0.21-1.60, thus having a significant effect on the overall reaction rate. Besides the pyrolysis of coal alone, the 50:50 coal/biomass blends had the highest reaction rate, ranging 1 x 10 super(9)-2 x 10 super(9) min super(-1). The experimental results may provide useful data for power generation industries for the development of co-firing options with biomass. JF - Bioresource Technology AU - Vuthaluru, H B AD - Department of Chemical Engineering, Curtin University of Technology, GPO Box 1987, Perth, WA 6845, Australia, h.vuthaluru@exchange.curtin.edu.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 187 EP - 195 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 92 IS - 2 SN - 0960-8524, 0960-8524 KW - Biotechnology and Bioengineering Abstracts KW - Coal KW - Biomass KW - Thermal degradation KW - Co-pyrolysis co-firing KW - Pyrolysis KW - Temperature effects KW - Triticum aestivum KW - Fuels KW - Wastes KW - Straw KW - W 30950:Waste Treatment & Pollution Clean-up UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20729409?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioresource+Technology&rft.atitle=Investigations+into+the+pyrolytic+behaviour+of+coal%2Fbiomass+blends+using+thermogravimetric+analysis&rft.au=Vuthaluru%2C+H+B&rft.aulast=Vuthaluru&rft.aufirst=H&rft.date=2004-04-01&rft.volume=92&rft.issue=2&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Bioresource+Technology&rft.issn=09608524&rft_id=info:doi/10.1016%2Fj.biortech.2003.08.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Pyrolysis; Fuels; Wastes; Straw; Coal; Biomass; Triticum aestivum DO - http://dx.doi.org/10.1016/j.biortech.2003.08.008 ER - TY - JOUR T1 - Ecological filtering of exotic plants in an Australian sub-alpine environment AN - 19770081; 5902896 AB - We investigated some of the factors influencing exotic invasion of native sub-alpine plant communities at a site in southeast Australia. Structure, floristic composition and invasibility of the plant communities and attributes of the invasive species were studied. To determine the plant characteristics correlated with invasiveness, we distinguished between roadside invaders, native community invaders and non-invasive exotic species, and compared these groups across a range of traits including functional group, taxonomic affinity, life history, mating system and morphology. Poa grasslands and Eucalyptus-Poa woodlands contained the largest number of exotic species, although all communities studied appeared resilient to invasion by most species. Most community invaders were broad-leaved herbs while roadside invaders contained both herbs and a range of grass species. Over the entire study area the richness and cover of native and exotic herbaceous species were positively related, but exotic herbs were more negatively related to cover of specific functional groups (e.g. trees) than native herbs. Compared with the overall pool of exotic species, those capable of invading native plant communities were disproportionately polycarpic, Asteracean and cross-pollinating. Our data support the hypothesis that strong ecological filtering of exotic species generates an exotic assemblage containing few dominant species and which functionally converges on the native assemblage. These findings contrast with those observed in the majority of invaded natural systems. We conclude that the invasion of closed sub-alpine communities must be viewed in terms of the unique attributes of the invading species, the structure and composition of the invaded communities and the strong extrinsic physical and climatic factors typical of the sub-alpine environment. Nomenclature: Australian Plant Name Index (APNI); Abbreviations: KNP = Kosciuszko National Park; MRPP = Multi response permutation procedure; VE = Variance explained. JF - Journal of Vegetation Science AU - Godfree, R AU - Lepschi, B AU - Mallinson, D AD - CSIRO Plant Industry, GPO Box 1600, Canberra, ACT, Australia, 2601, lepschi@csiro.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 227 EP - 236 PB - International Association of Vegetation Science VL - 15 IS - 2 SN - 1100-9233, 1100-9233 KW - Ecology Abstracts; Sustainability Science Abstracts KW - Grasslands KW - Mating KW - Life history KW - Roadsides KW - Poa KW - Plant communities KW - Sub-alpine environments KW - Introduced species KW - Herbs KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19770081?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Vegetation+Science&rft.atitle=Ecological+filtering+of+exotic+plants+in+an+Australian+sub-alpine+environment&rft.au=Godfree%2C+R%3BLepschi%2C+B%3BMallinson%2C+D&rft.aulast=Godfree&rft.aufirst=R&rft.date=2004-04-01&rft.volume=15&rft.issue=2&rft.spage=227&rft.isbn=&rft.btitle=&rft.title=Journal+of+Vegetation+Science&rft.issn=11009233&rft_id=info:doi/10.1043%2F1100-9233%282004%29015%280227%3AEFOEPI%292.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=1100-9233&volume=15&page=227 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Poa; Introduced species; Herbs; Plant communities; Roadsides; Sub-alpine environments; Mating; Life history; Grasslands DO - http://dx.doi.org/10.1043/1100-9233(2004)015(0227:EFOEPI)2.0.CO;2 ER - TY - JOUR T1 - Generation of SUMO-1 modified proteins in E. coli: towards understanding the biochemistry/structural biology of the SUMO-1 pathway AN - 19714737; 7492167 AB - Here, we developed a binary vector system that introduces a synthetic SUMO-1 conjugation pathway into Escherichia coli and demonstrated that large amounts of sumoylated Ran GTPase activating protein 1 C-terminal region (RanGAP1-C2), Ran binding protein 2 internal repeat domain, p53 and promyelocytic leukemia were efficiently produced. The sumoylated recombinant RanGAP1-C2 appeared to retain the in vivo properties, since it was specifically sumoylated at lysine 517 as expected from in vivo studies. Our findings indicate the establishment of a biosynthetic route for producing large amounts of sumoylated recombinant proteins that will open up new avenues for studying the biochemical and structural aspects of the SUMO-1 modification pathway. JF - FEBS Letters AU - Uchimura, Yasuhiro AU - Nakao, Mitsuyoshi AU - Saitoh, Hisato AD - Department of Regeneration Medicine, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan, hisa@gpo.kumamoto-u.ac.jp Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 85 EP - 90 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 564 IS - 1-2 SN - 0014-5793, 0014-5793 KW - Microbiology Abstracts B: Bacteriology KW - Author Keywords: Posttranslational modification KW - SUMO-1 KW - Ran GTPase activating protein 1 KW - Ran binding protein 2 KW - Promyelocytic leukemia KW - p53 KW - Escherichia coli KW - Lysine KW - Promyeloid leukemia KW - Guanosinetriphosphatase KW - p53 protein KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19714737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEBS+Letters&rft.atitle=Generation+of+SUMO-1+modified+proteins+in+E.+coli%3A+towards+understanding+the+biochemistry%2Fstructural+biology+of+the+SUMO-1+pathway&rft.au=Uchimura%2C+Yasuhiro%3BNakao%2C+Mitsuyoshi%3BSaitoh%2C+Hisato&rft.aulast=Uchimura&rft.aufirst=Yasuhiro&rft.date=2004-04-01&rft.volume=564&rft.issue=1-2&rft.spage=85&rft.isbn=&rft.btitle=&rft.title=FEBS+Letters&rft.issn=00145793&rft_id=info:doi/10.1016%2FS0014-5793%2804%2900321-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Promyeloid leukemia; Lysine; p53 protein; Guanosinetriphosphatase; Escherichia coli DO - http://dx.doi.org/10.1016/S0014-5793(04)00321-7 ER - TY - JOUR T1 - Can the Important Bird Area approach improve the Antarctic Protected Area System? AN - 19404476; 8710578 AB - The selection of sites that comprise the existing network of Antarctic protected areas has been largely ad hoc, driven by national interests rather than concerted efforts to ensure systematic and representative coverage of the Antarctic environment. Consequently there are gaps in coverage of all major ecosystems, in particular areas kept inviolate from human activity, inland lakes, and marine protected areas. Annex V of the 1991 Protocol on Environmental Protection to the Antarctic Treaty provides a list of values to be protected within a network of Antarctic Specially Protected Areas (ASPAs), but provides no quantitative methods for site identification and prioritisation. The Antarctic Important Bird Area (IBA) Inventory is a joint initiative of BirdLife International and the Scientific Committee on Antarctic Research Group of Experts on Birds (formerly the Bird Biology Subcommittee). The Antarctic IBA Inventory has identified 119 candidate IBAs, 97 of which are not currently protected as ASPAs. The IBA Inventory can improve the Antarctic Protected Area System (PAS) in that it provides a method by which to identify and prioritise sites for their potential inclusion in the Antarctic PAS. JF - Polar Record AU - Harris, Jane W AU - Woehler, Eric J AD - Institute of Antarctic and Southern Ocean Studies, University of Tasmania, GPO Box 252-77, Hobart, Tasmania 7001, Australia, eric.woehler@aad.gov.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 97 EP - 105 PB - Cambridge University Press, The Edinburgh Building, VL - 40 IS - 2 SN - 0032-2474, 0032-2474 KW - Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts; Sustainability Science Abstracts KW - Marine KW - Inventories KW - Ecosystems KW - marine protected areas KW - committees KW - Man-induced effects KW - Environmental protection KW - Joints KW - Aves KW - protected areas KW - Lakes KW - Nature conservation KW - Marine parks KW - Cadmium KW - Human factors KW - Q5 08523:Conservation, wildlife management and recreation KW - O 4090:Conservation and Environmental Protection KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08121:Law, policy, economics and social sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19404476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Polar+Record&rft.atitle=Can+the+Important+Bird+Area+approach+improve+the+Antarctic+Protected+Area+System%3F&rft.au=Harris%2C+Jane+W%3BWoehler%2C+Eric+J&rft.aulast=Harris&rft.aufirst=Jane&rft.date=2004-04-01&rft.volume=40&rft.issue=2&rft.spage=97&rft.isbn=&rft.btitle=&rft.title=Polar+Record&rft.issn=00322474&rft_id=info:doi/10.1017%2FS0032247403003322 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Marine parks; Nature conservation; Man-induced effects; Environmental protection; Inventories; Lakes; Joints; Aves; protected areas; Ecosystems; marine protected areas; committees; Cadmium; Human factors; Marine DO - http://dx.doi.org/10.1017/S0032247403003322 ER - TY - JOUR T1 - Biogeochemical marine ecosystem models II: the effect of physiological detail on model performance AN - 19399641; 5859033 AB - The level of detail required to efficiently capture system dynamics in ecosystem models has not been well defined. To this end an ecosystem model of a generalised temperate bay, Bay Model 2 (BM2), was constructed. It is a trophically diverse biogeochemical model built using the functional groups from another ecosystem model, the Integrated Generic Bay Ecosystem Model (IGBEM) and the general framework from a model of Port Phillip Bay (PPB), Australia. BM2 captures the essential features of real marine systems, it is also capable of reproducing realistic levels of biomass and conforms with known ecological relationships. The model's performance is not as good for some of the poorly known groups (like infauna) or when environmental conditions undergo extreme change. Despite this, the overall performance of BM2 indicated, it is as capable of representing systems as accurately as more physiologically detailed ecosystem models, such as IGBEM. This shows that physiological detail is not always required and that simpler formulations, such as those employed in BM2, are generally adequate for learning and general predictive purposes. This is important because, in comparison with IGBEM, BM2 uses substantially fewer parameters and has lower development, computation and maintenance costs. JF - Ecological Modelling AU - Fulton, E A AU - Parslow, J S AU - Smith, ADM AU - Johnson, C R AD - CSIRO Division of Marine Research, GPO Box 1538, Hobart, Tasmania 7001, Australia, beth.fulton@csiro.au Y1 - 2004/04// PY - 2004 DA - April 2004 SP - 371 EP - 406 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 173 IS - 4 SN - 0304-3800, 0304-3800 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Prediction KW - Meiobenthos KW - PSE, Australia, Victoria, Port Phillip Bay KW - Interspecific relationships KW - Marine environment KW - Biogeochemistry KW - Environmental conditions KW - Ecosystem models KW - Modelling KW - Q1 08482:Ecosystems and energetics KW - Q2 09181:General KW - D 04003:Modeling, mathematics, computer applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19399641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Biogeochemical+marine+ecosystem+models+II%3A+the+effect+of+physiological+detail+on+model+performance&rft.au=Fulton%2C+E+A%3BParslow%2C+J+S%3BSmith%2C+ADM%3BJohnson%2C+C+R&rft.aulast=Fulton&rft.aufirst=E&rft.date=2004-04-01&rft.volume=173&rft.issue=4&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2003.09.024 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-01-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Prediction; Meiobenthos; Interspecific relationships; Biogeochemistry; Environmental conditions; Modelling; Marine environment; Ecosystem models; PSE, Australia, Victoria, Port Phillip Bay DO - http://dx.doi.org/10.1016/j.ecolmodel.2003.09.024 ER - TY - JOUR T1 - Distinguishing sources of base cations in irrigated and natural soils: evidence from strontium isotopes AN - 17767456; 5927941 AB - Strontium isotope ratios ( super(87)Sr/ super(86)Sr) of soil solids, soil cation extracts, irrigation water and plant material are used to determine strontium and therefore cation sources and fluxes in irrigated and natural soil-plant systems. Strontium isotopes of soil solids from four soil profiles (two irrigated vineyard soils and two 'natural' profiles from nearby reserves) show large differences between soil horizons with depth. These differences are not reflected in super(87)Sr/ super(86)Sr ratios of soil labile cations, which show both little variation down-profile and much lower ratios than soil solids. In the undisturbed, natural soil profiles, labile cation super(87)Sr/ super(86)Sr ratios are close to the ratio of modern seawater, indicating that solutes of marine origin from precipitation are the primary input of strontium (and calcium) to the labile cation pool. In the irrigated soil profiles, super(87)Sr / super(86)Sr ratios of labile cations are consistently shifted towards that of the irrigation water. Mass-balance calculations using super(87)Sr/ super(86)Sr ratios of the different inputs to the labile cation pool indicate more than 90% of labile strontium is derived from precipitation solutes in unirrigated soils, and up to 44% from irrigation water solutes as an additional source in irrigated soils. The super(87)Sr/ super(86)Sr ratios of grapes grown in irrigated soils match precisely with those of the labile soil cations, demonstrating that cation nutrients are drawn wholly from the labile cation pool and have the same mix of precipitation, irrigation, and soil solid sources. The super(87)Sr/ super(86)Sr ratios of grapes grown in the irrigated soils may therefore vary over time depending on (1) the changing mix of irrigation water and local precipitation and (2) potential change to irrigation water. These findings suggest limitations to the use of strontium isotopes in the tracing of grapes and wines to their soil of origin. JF - Biogeochemistry AU - Green, G P AU - Bestland, E A AU - Walker, G S AD - Earth Sciences, SoCPES, Flinders University, GPO Box 2100, Adelaide 5001, Australia Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 199 EP - 225 PB - Kluwer Academic Publishers VL - 68 IS - 2 SN - 0168-2563, 0168-2563 KW - Water Resources Abstracts KW - Calcium KW - Biogeochemistry KW - Local Precipitation KW - Pools KW - Solids KW - Nutrients KW - Soil Horizons KW - Solutes KW - Cations KW - Strontium KW - Irrigation Water KW - Soil Profile KW - SW 0880:Chemical processes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17767456?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biogeochemistry&rft.atitle=Distinguishing+sources+of+base+cations+in+irrigated+and+natural+soils%3A+evidence+from+strontium+isotopes&rft.au=Green%2C+G+P%3BBestland%2C+E+A%3BWalker%2C+G+S&rft.aulast=Green&rft.aufirst=G&rft.date=2004-04-01&rft.volume=68&rft.issue=2&rft.spage=199&rft.isbn=&rft.btitle=&rft.title=Biogeochemistry&rft.issn=01682563&rft_id=info:doi/10.1023%2FB%3ABIOG.0000025743.34079.d3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Solutes; Calcium; Cations; Biogeochemistry; Local Precipitation; Pools; Nutrients; Solids; Irrigation Water; Strontium; Soil Horizons; Soil Profile DO - http://dx.doi.org/10.1023/B:BIOG.0000025743.34079.d3 ER - TY - JOUR T1 - Benthic fluxes of nitrogen in the tidal reaches of a turbid, high-nitrate sub-tropical river AN - 17594534; 5932143 AB - Benthic fluxes of dissolved inorganic nitrogen (NO3 super(-) and NH4 super(+)), dissolved organic nitrogen (DON), N2 (denitrification), O2 and TCO2 were measured in the tidal reaches of the Bremer River, south east Queensland, Australia. Measurements were made at three sites during summer and winter. Fluxes of NO3 super(-) were generally directed into the sediments at rates of up to -225 mu molNm super(-2)h super(-1). NH4 super(+) was mostly taken up by the sediments at rates of up to -52 mu molNm super(-2)h super(-1), its ultimate fate probably being denitrification. DON fluxes were not significant during winter. During summer, fluxes of DON were observed both into (-105 mu molm super(-2)h super(-1)) and out of (39 mu molm super(-2)h super(-1)) the sediments. Average N2 fluxes at all sampling sites were similar during summer (162 mu molNm super(-2)h super(-1)) and winter (153 mu molNm super(-2)h super(-1)). Denitrification was fed both by nitrification within the sediment and NO3 super(-) from the water column. Sediment respiration rates played an important role in the dynamics of nitrification and denitrification. NO3 super(-) fluxes were significantly related to TCO2 fluxes (p0.01), with a release of NO3 super(-) from the sediment only occurring at respiration rates below 1000 mu molCm super(-2)h super(-1). Rates of denitrification increased with respiration up to TCO2 fluxes of 1000 mu molCm super(-2)h super(-1). At sediment respiration rates above 1000 mu molCm super(-2)h super(-1), denitrification rates increased less rapidly with respiration in winter and declined during summer. On a monthly basis denitrification removed about 9% of the total nitrogen and 16% of NO3 super(-) entering the Bremer River system from known point sources. This is a similar magnitude to that estimated in other tidal river systems and estuaries receiving similar nitrogen loads. During flood events the amount of NO3 super(-) denitrified dropped to about 6% of the total river NO3 super(-) load. JF - Estuarine, Coastal and Shelf Science AU - Cook, P L AU - Eyre, B D AU - Leeming, R AU - Butler, E C AD - University of Tasmania, GPO Box 252-75, Hobart, Tasmania 7001, Australia, pcook@mpi-bremen.de Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 675 EP - 685 PB - Elsevier Ltd VL - 59 IS - 4 SN - 0272-7714, 0272-7714 KW - Sediment respiration rates KW - Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts; Aqualine Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 1: Biological Sciences & Living Resources KW - M2 551.468:Coastal Oceanography (551.468) KW - Q2 02183:Physics and chemistry KW - O 1080:Multi-disciplinary Studies KW - Q1 01482:Ecosystems and energetics KW - AQ 00002:Water Quality KW - SW 0890:Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17594534?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Benthic+fluxes+of+nitrogen+in+the+tidal+reaches+of+a+turbid%2C+high-nitrate+sub-tropical+river&rft.au=Cook%2C+P+L%3BEyre%2C+B+D%3BLeeming%2C+R%3BButler%2C+E+C&rft.aulast=Cook&rft.aufirst=P&rft.date=2004-04-01&rft.volume=59&rft.issue=4&rft.spage=675&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2003.11.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2005-04-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.ecss.2003.11.011 ER - TY - JOUR T1 - Experimental investigation of ultra-fine particle size distribution near a busy road AN - 16173000; 5860441 AB - In this paper, evolution of the size distribution of fine and ultra-fine particles emitted from vehicles on a busy road is investigated experimentally. In particular, several different modes (distinct maxima) of the particle size distribution are investigated as a function of the distance from the road. An unusual and complex evolution of these modes is discovered. In particular, it is demonstrated that some of the modes tend to shift towards smaller particle size, which has never been reported previously. Complex correlation between the modes is determined experimentally. In addition, for the first time, the total number concentration is clearly shown to go through a significant maximum at some distance from the road. This could have significant influence on the assessment of exposure to fine and ultra-fine particles in the vicinity of busy roads. JF - Atmospheric Environment AU - Gramotnev, G AU - Ristovski, Z AD - International Laboratory for Air Quality and Health, School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane QLD 4001, Australia, z.ristovski@qut.edu.au Y1 - 2004/04// PY - 2004 DA - Apr 2004 SP - 1767 EP - 1776 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 38 IS - 12 SN - 1352-2310, 1352-2310 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Particle size KW - Air pollution KW - Particle size distribution KW - Combustion products KW - Motor vehicles KW - Correlation analysis KW - Atmospheric pollution by road vehicles KW - Highways KW - Particulate atmospheric pollution KW - Exhaust emissions KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/16173000?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Experimental+investigation+of+ultra-fine+particle+size+distribution+near+a+busy+ro