TY - JOUR T1 - Direct and indirect suppression induced by anti-idiotype antibody in the inulin-bacterial levan antigenic system AN - 20053495; 8555180 AB - Our findings on the suppression of anti-inulin [ beta (2 --> 1) fructosan] antibody synthesis by anti-idiotype antibodies are reviewed in this communication. Treatment with anti-idiotype antibodies leads to suppression of those B cells which can secrete antibodies bearing that idiotype (direct suppression). This suppression was achieved in three models: maternally induced, pretreatment of 1-day old BALB/c mice with anti- idiotype antibody and similar treatment of adult BALB/c mice. Maternally and neonatally induced suppression was more profound and longer than suppression in adults. The direct suppression appears to be largely independent of T cell influence. In addition, we report a new phenomenon (indirect suppression), which is the inhibition by anti-E109 idiotype antibody of an E109 super(-) antibody response, to antigenic determinants borne on the same carrier molecule as the beta (2 --> 1 ) fructosan determinant. Indirect suppression provides an important model for probing aspects of the regulation of clonal expression through idiotype specific molecules. JF - Molecular Immunology AU - Bona, Constantin AU - Stein, Kathryn E AU - Lieberman, Rose AU - Paul, William E AD - Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, 20205, U.S.A. Y1 - 1979/12// PY - 1979 DA - Dec 1979 SP - 1093 EP - 1101 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 16 IS - 12 SN - 0161-5890, 0161-5890 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Molecular modelling KW - levan KW - Idiotypes KW - Lymphocytes B KW - Reviews KW - Antigenic determinants KW - Lymphocytes T KW - Antibody response KW - A 01490:Miscellaneous KW - J 02350:Immunology KW - F 06960:Molecular Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20053495?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+Immunology&rft.atitle=Direct+and+indirect+suppression+induced+by+anti-idiotype+antibody+in+the+inulin-bacterial+levan+antigenic+system&rft.au=Bona%2C+Constantin%3BStein%2C+Kathryn+E%3BLieberman%2C+Rose%3BPaul%2C+William+E&rft.aulast=Bona&rft.aufirst=Constantin&rft.date=1979-12-01&rft.volume=16&rft.issue=12&rft.spage=1093&rft.isbn=&rft.btitle=&rft.title=Molecular+Immunology&rft.issn=01615890&rft_id=info:doi/10.1016%2F0161-5890%2879%2990043-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Molecular modelling; levan; Lymphocytes B; Idiotypes; Antigenic determinants; Reviews; Lymphocytes T; Antibody response DO - http://dx.doi.org/10.1016/0161-5890(79)90043-9 ER - TY - JOUR T1 - Assessement of surgical procedures for Ménière's disease. AN - 85200807; pmid-376984 AB - There are numerous surgical procedures for the treatment of Meniere's disease, and the current status of their efficacy is controversial. A review of the literature is presented as a basis for the evaluation of the relative merit of these procedures. Emphasis is placed on endolymphatic sac procedures, sacculotomy, vestibular neurectomy and labyrinthectomy. Vestibular neurectomy and surgical labyrinthectomy provide high rates of improvement in vertigo. The hearing is frequently made worse by vestibular neurectomy. Endolymphatic sac procedures result in improvement in vertigo less frequently. They are most likely to improve hearing. Although sacculotomies are associated with improvement in vertigo in approximately 80% of patients, they are associated with high rates of hearing loss. JF - The Laryngoscope AU - Snow, J B AU - Kimmelman, C P AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1979 SP - 737 EP - 747 VL - 89 IS - 5 Pt 1 SN - 0023-852X, 0023-852X KW - Labyrinth KW - Meniere's Disease KW - Postoperative Complications KW - Human KW - Vestibular Nerve KW - Endolymphatic Sac KW - Hearing Loss KW - Vertigo UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85200807?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Assessement+of+surgical+procedures+for+M%C3%A9ni%C3%A8re%27s+disease.&rft.au=Snow%2C+J+B%3BKimmelman%2C+C+P&rft.aulast=Snow&rft.aufirst=J&rft.date=1979-05-01&rft.volume=89&rft.issue=5+Pt+1&rft.spage=737&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Radioisotope Dilution Assay (RIDA) for the Estimation of Polychlorinated Biphenyls (PCBs) AN - 1093463006; 17184417 AB - A radioisotope dilution assay (RIDA) having an accountability of 94a-'99% for the estimation of total polychlorinated biphenyls (PCBs) is described. Biological samples are spiked with a radioactive PCB of known specific activity. Lipids and PCBs are extracted from the samples by the use of chloroform:methanol (2:1 v/v). PCBs are separated from lipids either by sulfuric acid treatment or by gel permeation chromatography. The PCB fraction is further cleaned up using Florisil PR-60 and is perchlorinated. Decachlorobiphenyl is estimated by gas chromatography and radioactivity assayed by liquid scintillation counting. Because dilution of radioactivity is taken into consideration, the complete recovery of PCBs is not required for their estimation; thus, this method overcomes the handling losses in the cleanup, perchlorination, and preparation of samples. JF - Journal of Analytical Toxicology AU - Kohli, Krishan K AU - Albro, Phillip W AU - McKinney, James D AD - Environmental Chemistry Branch, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, NC 27709 Y1 - 1979/05// PY - 1979 DA - May 1979 SP - 125 EP - 128 PB - Preston Publications, Inc., 6600 W. Touhy Ave. Niles IL 60714 United States VL - 3 IS - 3 SN - 0146-4760, 0146-4760 KW - Toxicology Abstracts KW - polychlorinated biphenyls KW - Gas chromatography KW - Lipids KW - Scintillation KW - Radioisotopes KW - Sulfuric acid KW - Radioactivity KW - Enumeration KW - PCB KW - X 24390:Radioactive Materials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1093463006?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Analytical+Toxicology&rft.atitle=Radioisotope+Dilution+Assay+%28RIDA%29+for+the+Estimation+of+Polychlorinated+Biphenyls+%28PCBs%29&rft.au=Kohli%2C+Krishan+K%3BAlbro%2C+Phillip+W%3BMcKinney%2C+James+D&rft.aulast=Kohli&rft.aufirst=Krishan&rft.date=1979-05-01&rft.volume=3&rft.issue=3&rft.spage=125&rft.isbn=&rft.btitle=&rft.title=Journal+of+Analytical+Toxicology&rft.issn=01464760&rft_id=info:doi/ L2 - http://www.ingentaconnect.com/content/oup/jat/1979/00000003/00000003/art00012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - polychlorinated biphenyls; Gas chromatography; Scintillation; Lipids; Sulfuric acid; Radioisotopes; Enumeration; Radioactivity; PCB ER - TY - JOUR T1 - A mutant killer plasmid whose replication depends on a chromosomal "superkiller" mutation. AN - 733470623; 17248905 AB - Yeast strains carrying a 1.5 x 10(6) molecular weight linear double-stranded RNA in virus-like particles (M dsRNA, the killer plasmid or virus) secrete a toxin that is lethal to strains not carrying this plasmid. Recessive mutations in any of four chromosomal genes (called ski1-ski4) result in increased production of toxin activity. We report here a mutation of the killer plasmid (called [KIL-sd] for ski-dependent) that makes the killer plasmid dependent for its replication on the presence of a chromosomal mutation in any ski gene. Thus, the [KIL-sd] plasmid is lost from SKI(+) strains. When the wild-type killer plasmid, [KIL-k], is introduced into a ski2-2 [KIL-o] strain, the killer plasmid changes to a [KIL-sd] plasmid. This may represent a specific form of mutagenesis or selective replication in the ski2-2 strain of [KIL-sd] variants (mutants) in the normal [KIL-k] population. The ski2-1 and ski2-3 mutations do not convert [KIL-k] to [KIL-sd], but ski2-3 does allow maintenance of the [KIL-sd] plasmid. The [KIL-sd] plasmid thus lacks a plasmid site or product needed for replication in wild-type cells. JF - Genetics AU - Toh-E, A AU - Wickner, R B AD - Laboratory of Biochemical Pharmacology, National Institute of Arthritis, Metabolism and Digestive Diseases, National Institutes of Health, Bethesda, Maryand 20014. Y1 - 1979/04// PY - 1979 DA - April 1979 SP - 673 EP - 682 VL - 91 IS - 4 SN - 0016-6731, 0016-6731 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733470623?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Genetics&rft.atitle=A+mutant+killer+plasmid+whose+replication+depends+on+a+chromosomal+%22superkiller%22+mutation.&rft.au=Toh-E%2C+A%3BWickner%2C+R+B&rft.aulast=Toh-E&rft.aufirst=A&rft.date=1979-04-01&rft.volume=91&rft.issue=4&rft.spage=673&rft.isbn=&rft.btitle=&rft.title=Genetics&rft.issn=00166731&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-06-28 N1 - Date created - 2010-06-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Genetics. 1973 Aug;74(4):571-9 [17248628] J Bacteriol. 1978 Dec;136(3):1002-7 [363683] Proc Natl Acad Sci U S A. 1978 Sep;75(9):4224-8 [360211] Genetics. 1976 Sep;84(1):27-42 [791748] Proc Natl Acad Sci U S A. 1976 Oct;73(10):3651-5 [790391] Genet Res. 1969 Feb;13(1):71-83 [5771662] J Gen Virol. 1974 Mar;22(3):387-94 [4594342] J Bacteriol. 1974 Feb;117(2):681-6 [4590482] Proc Natl Acad Sci U S A. 1972 Oct;69(10):2846-9 [4562744] J Virol. 1976 Feb;17(2):472-6 [768518] Genetics. 1974 Mar;76(3):423-32 [4364866] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effect of kanamycin sulfate on the endocochlear dc potential of guinea pigs. AN - 85253092; pmid-420653 AB - The magnitudes of the endocochlear dc potential (EP) during adequate ventilation and during five minutes of anoxia were recorded in control guinea pigs and guinea pigs administered various dosages of kanamycin sulfate. The magnitudes of the EP after five minutes of anoxia were -44.6 +/- 5.9 mV in the controls and +26.6 +/- 9.9 mV in the guinea pigs that received kanamycin for seven or ten days. This change occurred after five or six days of administration of kanamycin. However, there was no significant change in the magnitude ot the EP with adequate ventilation with kanamycin intoxication. There is a significant correlation between the magnitude of the negative EP and the maximum output of the cochlear microphonics (r = -.770, P less than .001). These results suggest that the EP may not be the mathematical summation of the positive electrogenic potential and the negative diffusion potential. The mechanism for generating the negative EP during anoxia may have some relationship to hair cell integrity. JF - Archives of Otolaryngology (Chicago, Ill. : 1960) AU - Asakuma, S AU - Lowry, L D AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1979 SP - 145 EP - 148 VL - 105 IS - 3 SN - 0003-9977, 0003-9977 KW - Cochlea KW - Hair Cells KW - Guinea Pigs KW - Animal KW - Membrane Potentials KW - Kanamycin KW - Anoxia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85253092?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.atitle=Effect+of+kanamycin+sulfate+on+the+endocochlear+dc+potential+of+guinea+pigs.&rft.au=Asakuma%2C+S%3BLowry%2C+L+D%3BSnow%2C+J+B&rft.aulast=Asakuma&rft.aufirst=S&rft.date=1979-03-01&rft.volume=105&rft.issue=3&rft.spage=145&rft.isbn=&rft.btitle=&rft.title=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.issn=00039977&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Selection on recombination in a multi-locus system. AN - 733470624; 17248898 AB - The model of Wills and Miller (1976) for selection on recombination rates in finite populations was studied by means of a computer model involving 80 selected loci and a linked or unlinked modifier gene affecting the map length occupied by the selected loci. The selected loci were subject to heterozygote advantage, and multiplicative fitness interactions between loci were assumed. In all cases studied, selection for reduction in recombination out-weighed any selection for increased recombination that may have been present. JF - Genetics AU - Charlesworth, D AU - Charlesworth, B AD - Laboratory of Environmental Mutagenesis, National Institute of Environmental Health Sciences, P. O. Box 12233 Research Triangle Park, North Carolina 27709. Y1 - 1979/03// PY - 1979 DA - March 1979 SP - 575 EP - 580 VL - 91 IS - 3 SN - 0016-6731, 0016-6731 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733470624?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Genetics&rft.atitle=Selection+on+recombination+in+a+multi-locus+system.&rft.au=Charlesworth%2C+D%3BCharlesworth%2C+B&rft.aulast=Charlesworth&rft.aufirst=D&rft.date=1979-03-01&rft.volume=91&rft.issue=3&rft.spage=575&rft.isbn=&rft.btitle=&rft.title=Genetics&rft.issn=00166731&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-06-28 N1 - Date created - 2010-06-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Genetics. 1976 Feb;82(2):377-99 [1261798] Theor Popul Biol. 1970 May;1(1):88-100 [5527627] Genetics. 1976 Mar 25;82(3):547-58 [1269909] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Selection on recombination in clines. AN - 733470616; 17248899 AB - Computer runs have been done to examine Slatkin's (1975) model for selection on recombination rates in linear sets of populations with environmental changes affecting two loci. In order to determine whether the suggested selection pressures on recombination do, in fact, exist, we follow the changes in frequency at a third locus that is polymorphic for alleles affecting the recombination rate between the two selected loci. With haploid or diploid selection models, there can be selection for increased recombination if the parameter values are chosen suitably, but changes in parameter values often lead to changes in the direction of selection, so that decreased recombination is favored. The selection for increased recombination is usually weak, while that for decreased recombination is frequently much stronger. Weaker selection on the selected loci often leads to increasing selection for decreased recombination. JF - Genetics AU - Charlesworth, D AU - Charlesworth, B AD - Laboratory of Environmental Mutagenesis, National Institute of Environmental Health Sciences, P. O. Box 12233, Research Triangle Park, North Carolina 27709. Y1 - 1979/03// PY - 1979 DA - March 1979 SP - 581 EP - 589 VL - 91 IS - 3 SN - 0016-6731, 0016-6731 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733470616?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Genetics&rft.atitle=Selection+on+recombination+in+clines.&rft.au=Charlesworth%2C+D%3BCharlesworth%2C+B&rft.aulast=Charlesworth&rft.aufirst=D&rft.date=1979-03-01&rft.volume=91&rft.issue=3&rft.spage=581&rft.isbn=&rft.btitle=&rft.title=Genetics&rft.issn=00166731&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-06-28 N1 - Date created - 2010-06-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Genetics. 1973 Dec;75(4):733-56 [4778791] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Screening for neurobehavioral toxicity: the need for and examples of validation of testing procedures. AN - 75025096; 233760 AB - The need for a sensitive and reliable screen to assess environmental agents for potential behavioral and neurological toxicity is discussed. Factors involving strategy, choice of animals and doses, route of administration, duration of study and requirements for the selection of neurobehavioral tests are also evaluated. The primary emphasis concerns the need for standardization and validation of neurobehavioral tests to be used in neurotoxicology. It is suggested that test validation be accomplished by comparing the observed results of known neurotoxicants in animal models which are chosen to predict effects based on reported human symptomatology. As a means of demonstrating how test validation is used in our laboratory, data from a number of experiments concerning the effects of a variety of chemical agents on three measures of motor functioning were discussed. The neurobehavioral effects of acrylamide, and agent known to produce "dying-back" axonopathies, were assessed using separate techniques presumed to measure hindlimb and forelimb functioning and general motor activity. The prediction that acrylamide will first decrease hindlimb functioning, while decreasing forelimb grip strength and motor activity at higher doses, was confirmed. The validity of the hindlimb measurement was supported using a neurotoxicant, carbon disulfide, known to affect motor functioning in a manner similar to acrylamide. The validity of the forelimb technique was shown indirectly using normative data collected from rats of both sexes tested at various ages, i.e., males were stronger than females and grip scores changed as a function of age. The relative sensitivities of the fore- and hindlimb measurements were found to be approximately the same when used to assess the effects of known muscle relaxants, such as phenobarbital and chlordiazepoxide. Finally, it was predicted and confirmed that an environmental agent believed to affect behavior secondarily to effects on other organ systems would affect all measures of motor functioning at approximately the same dose. JF - Neurobehavioral toxicology AU - Tilson, H A AU - Mitchell, C L AU - Cabe, P A AD - Laboratory of Behavioral and Neurological Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709. Y1 - 1979 PY - 1979 DA - 1979 SP - 137 EP - 148 VL - 1 Suppl 1 SN - 0191-3581, 0191-3581 KW - Environmental Pollutants KW - 0 KW - Polybrominated Biphenyls KW - Index Medicus KW - Rats KW - Animals KW - Rats, Inbred F344 KW - Polybrominated Biphenyls -- toxicity KW - Drug Evaluation, Preclinical KW - Male KW - Female KW - Behavior, Animal -- drug effects KW - Environmental Pollutants -- toxicity KW - Nervous System -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/75025096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurobehavioral+toxicology&rft.atitle=Screening+for+neurobehavioral+toxicity%3A+the+need+for+and+examples+of+validation+of+testing+procedures.&rft.au=Tilson%2C+H+A%3BMitchell%2C+C+L%3BCabe%2C+P+A&rft.aulast=Tilson&rft.aufirst=H&rft.date=1979-01-01&rft.volume=1+Suppl+1&rft.issue=&rft.spage=137&rft.isbn=&rft.btitle=&rft.title=Neurobehavioral+toxicology&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1988-04-01 N1 - Date created - 1988-04-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-17 ER - TY - CPAPER T1 - Invisible Referral Networks: Exchange Patterns between Self-Helpers and Formal Alcoholism Programs T2 - North Central Sociological Association AN - 61730470; 79S10727 AB - An important issue in natural support networks is their relationship with professional human service organizations in the community. It is shown here that there is an invisible & very distinctive linkage network between some formal alcoholism treatment programs & self-helpers from Alcoholics Anonymous (AA). Three distinctive features are: (1) the relatively recent development of many formal alcoholism treatment programs, (2) the relatively large numbers & social influence of recovered alcoholic self-helpers in some communities, & (3) the self-helpers' experiential knowledge or specialized expertise about alocholism & its management. Experiential knowledge is know-how & wisdom gained from reflection about one's personal experiencing of a phenomenon. Patterns of exchange & referral among self-helpers & formal treatment programs are illustrated, using national data on client referrals from over 200 programs, as well as two focused interview studies of self-helpers & of directors of alcoholism treatment programs & national program administrators. The literature in sociology of health & illness has considered two types of referral systems: lay & professional. Suggestions for an additional third form, the experiential referral system, are made. This approach predicts that as other self-help groups increase in strength & experiential knowledge, experiential referral systems for other health problems will be or are already being developed with professionals. JF - North Central Sociological Association AU - Borkman, Thomasina S Y1 - 1979///0, PY - 1979 DA - 0, 1979 KW - alcoholism treatment programs, Alcoholics Anonymous members referral exchange network KW - exchange, referral patterns data, experiential knowledge factor KW - Network/Networks KW - Alcohol KW - Program/Programs/Programmer/ Programmers KW - proceeding KW - 2147: social problems and social welfare; sociology of crime & victimology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61730470?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=North+Central+Sociological+Association&rft.atitle=Invisible+Referral+Networks%3A+Exchange+Patterns+between+Self-Helpers+and+Formal+Alcoholism+Programs&rft.au=Borkman%2C+Thomasina+S&rft.aulast=Borkman&rft.aufirst=Thomasina&rft.date=1979-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=North+Central+Sociological+Association&rft.issn=&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2009-03-10 N1 - Publication note - 1979 N1 - Last updated - 2016-09-28 ER - TY - CPAPER T1 - DSM -- III: Diagnoses as Emerging Norms T2 - Society for the Study of Social Problems AN - 61721741; 79S10962 AB - The development of the new diagnostic system in psychiatry is analyzed as an example of the emergent norm approach to collective behavior. Sources of new categories such as DSM-III are the heterogeneous & constantly changing cultural system, & changes in the natural world. Support for a new category is due partly to the perceptual efficiency of the category itself, including its linkage with other categories. Support for a new category will emerge also from the control over natural events it provides, & here the question of the "scientific" validity of the category arises. Finally, support for a new category also arises when the new category affects the flow of resources, & here the question of the "democratic" validity of the category arises. Examples from the history of psychiatry, up to & including the development of DSM-III, illustrate this approach. JF - Society for the Study of Social Problems AU - Eaton, William W Y1 - 1979///0, PY - 1979 DA - 0, 1979 KW - psychiatry, new diagnostic system, DSM-III KW - emergent norm approach to collective behavior, new category, support factors KW - System/Systems KW - Behavior/Behavioral KW - Psychiatry/Psychiatric KW - Collective/Collectives/ Collectivism/ Collectivist KW - Diagnosis/Diagnostic KW - Mental illness/Mentally ill KW - proceeding KW - 2046: sociology of health and medicine; social psychiatry (mental health) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61721741?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Society+for+the+Study+of+Social+Problems&rft.atitle=DSM+--+III%3A+Diagnoses+as+Emerging+Norms&rft.au=Eaton%2C+William+W&rft.aulast=Eaton&rft.aufirst=William&rft.date=1979-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Society+for+the+Study+of+Social+Problems&rft.issn=&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2009-03-10 N1 - Publication note - 1979 N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - Manic-Depressive Illness; Psychodynamic Features of Multigenerational Families AN - 61520278; 198100374 AB - Psychodynamic features of families with multigenerational bipolar manic-depressive illness are described on the basis of clinical studies of 6 families. The maintenance of family pathology may be influenced by such factors as repetitive maladaptive patterns, avoidance of affect, unrealistic standards of conformity, absence of intimate relationships apart from family, displaced parental low self-esteem, & fears related to illness heritability. Treatment implications are identified, stressing the need for group rather than one-to-one therapeutic approaches. Modified HA. JF - American Journal of Orthopsychiatry AU - Davenport, Yolande B AU - Adland, Marvin L AU - Gold, Philip W AU - Goodwin, Frederick K AD - Clinical Psychobiology Branch NIMH Clinical Center Room 4S-239, Bethesda MD 20014 Y1 - 1979/01// PY - 1979 DA - January 1979 SP - 24 EP - 35 VL - 49 IS - 1 SN - 0002-9432, 0002-9432 KW - manic-depressive illness KW - multigenerational families' psychodynamic features, treatment implications KW - clinical studies description KW - Dynamic/Dynamics KW - Manic-depressive/Manic-depressives/ Manic-depression KW - Family/Families KW - Psychology/Psychological/ Psychologically/ Psychologism KW - article KW - 6120: social welfare UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61520278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=CAGE+AND+KENNEL+WASTE+WATER&rft.au=Jaworski%2C+Na%3BHICKEY%2C+JLS&rft.aulast=Jaworski&rft.aufirst=Na&rft.date=1962-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - Social Services Abstracts N1 - Date revised - 2007-05-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Manic-depressive/Manic-depressives/ Manic-depression; Psychology/Psychological/ Psychologically/ Psychologism; Dynamic/Dynamics; Family/Families ER - TY - JOUR T1 - Isolation of stable mutagenic photodecomposition products of benzo(a)pyrene by thin-layer chromatography AN - 13906889; 198000422 AB - Benzopyrene is examined to show the effects of UV radiation on its stability in solution and on TLC plates, to isolate the stable photodecomposition products and to test for their possible mutagenic activity. When solutions of benzopyrene were spotted on silica gel, alumina, cellulose and reversed-phase TLC plates it was shown that two regions from the plates were direct acting mutagens. JF - Journal of Liquid Chromatography AU - Issaq, HJ AU - Andrews, A W AU - Janini, G M AU - Barr, E W AD - NATIONAL CANCER INSTITUTE Y1 - 1979 PY - 1979 DA - 1979 SP - 319 EP - 325 VL - 2 IS - 3 SN - 0148-3919, 0148-3919 KW - Aqualine Abstracts KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/13906889?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Liquid+Chromatography&rft.atitle=Isolation+of+stable+mutagenic+photodecomposition+products+of+benzo%28a%29pyrene+by+thin-layer+chromatography&rft.au=Issaq%2C+HJ%3BAndrews%2C+A+W%3BJanini%2C+G+M%3BBarr%2C+E+W&rft.aulast=Issaq&rft.aufirst=HJ&rft.date=1979-01-01&rft.volume=2&rft.issue=3&rft.spage=319&rft.isbn=&rft.btitle=&rft.title=Journal+of+Liquid+Chromatography&rft.issn=01483919&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2000-09-01 N1 - Last updated - 2011-12-12 ER - TY - JOUR T1 - Electrical resistance of the cochlear partition. AN - 85165225; pmid-757229 AB - The relationship between the calculated value of the effective electrical resistance of the cochlear partition and the distance between the electrode for measuring the EP and the stimulating electrodes has been studied. The calculated value of the effective electrical resistance of the cochlear partition declines linearly with increasing distance between these electrodes. The correlation coefficient (r) is -0.806. In calculations of the effective electrical resistance of the cochlear partition, attention must be paid to the distance between the microelectrodes. JF - Hearing Research AU - Asakuma, S AU - Snow, J B AU - Murakami, Y AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1978 SP - 25 EP - 30 VL - 1 IS - 1 SN - 0378-5955, 0378-5955 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85165225?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Hearing+Research&rft.atitle=Electrical+resistance+of+the+cochlear+partition.&rft.au=Asakuma%2C+S%3BSnow%2C+J+B%3BMurakami%2C+Y&rft.aulast=Asakuma&rft.aufirst=S&rft.date=1978-10-01&rft.volume=1&rft.issue=1&rft.spage=25&rft.isbn=&rft.btitle=&rft.title=Hearing+Research&rft.issn=03785955&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Evaluation of randomized preoperative and postoperative radiation therapy for supraglottic carcinoma. Preliminary report. AN - 85177044; pmid-718066 AB - One hundred and ten patients with supraglottic squamous cell carcinoma have been randomized for preoperative radiation therapy and surgery versus surgery and postoperative radiation therapy. Data have been analyzed on 94 patients in this preliminary report. The differences between the two groups with respect to local control and survival are not statistically significant at this time. Additional accrual and continued follow-up are necessary in order to make a more definite treatment comparison. JF - The Annals of Otology, Rhinology, and Laryngology AU - Snow, J B AU - Gelber, R D AU - Kramer, S AU - Davis, L W AU - Marcial, V A AU - Lowry, L D AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1978 SP - 686 EP - 691 VL - 87 IS - 5 Pt 1 SN - 0003-4894, 0003-4894 KW - Preoperative Care KW - Research Support, U.S. Gov't, P.H.S. KW - Postoperative Care KW - Postoperative Complications KW - Humans KW - Neoplasm Metastasis KW - Radiotherapy KW - Laryngeal Neoplasms KW - Neoplasm Recurrence, Local KW - Carcinoma, Squamous Cell UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85177044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Evaluation+of+randomized+preoperative+and+postoperative+radiation+therapy+for+supraglottic+carcinoma.+Preliminary+report.&rft.au=Snow%2C+J+B%3BGelber%2C+R+D%3BKramer%2C+S%3BDavis%2C+L+W%3BMarcial%2C+V+A%3BLowry%2C+L+D&rft.aulast=Snow&rft.aufirst=J&rft.date=1978-09-01&rft.volume=87&rft.issue=5+Pt+1&rft.spage=686&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Accelerated Atrioventricular Conduction in Fabry's Disease: A Case Report AN - 20063552; 10098103 AB - Three unrelated men with Fabry's disease (angiokeratoma corporis diffu sum universale) and accelerated atrioventricular conduction are described. AQn His bundle electrogram in one patient who reported episodes of tachycardia demonstrated a prolonged deflection preceding the ventricular complex. This deflection is thought to represent an abnormal His bundle potential, possible resulting from glycolpid deposition. In the second patient the PR interval decreased from 0.18 to 0.11 second during 10 years, and in the third patient it decreased from 0.12 to 0.10 seconds during 13 years. Accelerated atrioventricu lar conduction may develop in Fabry's disease. JF - Angiology AU - Rowe, John W AU - Caralis, Dennis G AD - Division of Clinical Physiology, Gerontology Research Center, National Institute of Child Health and Human Development, National Institutes of Health, and the Johns Hopkins University School of Medicine, Baltimore, Maryland Y1 - 1978/07// PY - 1978 DA - Jul 1978 SP - 562 EP - 568 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 29 IS - 7 SN - 0003-3197, 0003-3197 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Case reports KW - Tachycardia KW - Fabry's disease KW - Conduction KW - A 01490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20063552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Angiology&rft.atitle=Accelerated+Atrioventricular+Conduction+in+Fabry%27s+Disease%3A+A+Case+Report&rft.au=Rowe%2C+John+W%3BCaralis%2C+Dennis+G&rft.aulast=Rowe&rft.aufirst=John&rft.date=1978-07-01&rft.volume=29&rft.issue=7&rft.spage=562&rft.isbn=&rft.btitle=&rft.title=Angiology&rft.issn=00033197&rft_id=info:doi/10.1177%2F000331977802900709 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-07-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Case reports; Tachycardia; Fabry's disease; Conduction DO - http://dx.doi.org/10.1177/000331977802900709 ER - TY - JOUR T1 - Long-Term Follow-Up of Behavior Modification With High-Risk Adolescents AN - 21021441; 10304240 AB - This investigation reports on follow-up information received from past participants of a school-based social learning program designed for problem adolescents. The follow-up occurred approximately five years after the students' participation in the program. The attitudes and performance of 15 of the original 24 adolescents were assessed on a range of self-report measures, incorporating variables such as their employment and educational status, evaluation of program participation, involvement in leisure-time and community activities, relationships with family and friends, and anticipated aversive consequences of engaging in delinquent acts. Issues of importance to the execution of follow-up studies are reviewed. Data resulting from this pilot study fail to conclusively demonstrate the long-term merits of the behavioral program with this population. JF - Criminal Justice and Behavior AU - McCombs, Dan AU - Filipczak, James AU - Friedman, Robert M AU - Wodarski, John S AD - St. Elizabeth's Hospital-National Institute of Mental Health Y1 - 1978/03// PY - 1978 DA - Mar 1978 SP - 21 EP - 34 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 5 IS - 1 SN - 0093-8548, 0093-8548 KW - Risk Abstracts KW - employment KW - Behavior KW - Reviews KW - Adolescents KW - attitudes KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21021441?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Criminal+Justice+and+Behavior&rft.atitle=Long-Term+Follow-Up+of+Behavior+Modification+With+High-Risk+Adolescents&rft.au=McCombs%2C+Dan%3BFilipczak%2C+James%3BFriedman%2C+Robert+M%3BWodarski%2C+John+S&rft.aulast=McCombs&rft.aufirst=Dan&rft.date=1978-03-01&rft.volume=5&rft.issue=1&rft.spage=21&rft.isbn=&rft.btitle=&rft.title=Criminal+Justice+and+Behavior&rft.issn=00938548&rft_id=info:doi/10.1177%2F009385487800500102 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - employment; Behavior; Reviews; attitudes; Adolescents DO - http://dx.doi.org/10.1177/009385487800500102 ER - TY - JOUR T1 - Neoplasms of the head and neck in children. AN - 85208770; pmid-622909 JF - Advances in Oto-Rhino-Laryngology AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1978 SP - 115 EP - 130 VL - 23 SN - 0065-3071, 0065-3071 KW - Antineoplastic Agents KW - Human KW - Child KW - Head and Neck Neoplasms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85208770?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Oto-Rhino-Laryngology&rft.atitle=Neoplasms+of+the+head+and+neck+in+children.&rft.au=Snow%2C+J+B&rft.aulast=Snow&rft.aufirst=J&rft.date=1978-01-01&rft.volume=23&rft.issue=&rft.spage=115&rft.isbn=&rft.btitle=&rft.title=Advances+in+Oto-Rhino-Laryngology&rft.issn=00653071&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Increased susceptibility of tumor cells and chicken erythrocytes to lysis by antibody and complement after treatment with aminoethylisothiouronium bromide hydrobromide (AET). AN - 74458486; 401313 AB - After treatment with aminoethylisothiouronium bromide hydrobromide (AET), the ascites forms of the diethylnitrosamine-induced guinea pig hepatomas, line-1 and line-10, were susceptible or more susceptible to killing in vitro by certain combinations of tumor-specific or IgM anti-Forssman antibody and either human or guinea pig complement. Since AET could be toxic to either cell line, conditions of pH, concentration of AET, and duration of exposure of the cells to the reagent were determined that resulted in enhanced susceptibility without significantly affecting cell viability. Chicken erythrocytes (CE) also were tested and AET-treated cells found to be more susceptible to lysis by IgM anti-Forssman antibody and guinea pig complement. The enhancement apparently was not due to increased ability of AET-treated CE to fix antibody. In contrast to CE, the lytic susceptibility of sheep cells was not affected by AET treatment. In addition to AET, several drugs and enzymes that also can affect the susceptibility of the tumor cells to antibody and complement were tested and found to be ineffective against CE. Since AET reputedly acts directly on the cell surface, it seems reasonable to assume that the increased susceptibility of the tumor cells and CE to antibody and complement may result from a modification of the cell surface. JF - Journal of immunopharmacology AU - Langone, J J AU - Borsos, T AD - Laboratory of Immunobiology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014. PY - 1978 SP - 43 EP - 59 VL - 1 IS - 1 SN - 0163-0571, 0163-0571 KW - beta-Aminoethyl Isothiourea KW - 151-16-6 KW - Complement System Proteins KW - 9007-36-7 KW - Index Medicus KW - Animals KW - Chickens KW - Guinea Pigs KW - Sheep KW - In Vitro Techniques KW - beta-Aminoethyl Isothiourea -- pharmacology KW - Erythrocytes -- drug effects KW - Tumor Cells, Cultured -- immunology KW - Complement System Proteins -- immunology KW - Erythrocytes -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/74458486?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+immunopharmacology&rft.atitle=Increased+susceptibility+of+tumor+cells+and+chicken+erythrocytes+to+lysis+by+antibody+and+complement+after+treatment+with+aminoethylisothiouronium+bromide+hydrobromide+%28AET%29.&rft.au=Langone%2C+J+J%3BBorsos%2C+T&rft.aulast=Langone&rft.aufirst=J&rft.date=1978-01-01&rft.volume=1&rft.issue=1&rft.spage=43&rft.isbn=&rft.btitle=&rft.title=Journal+of+immunopharmacology&rft.issn=01630571&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1990-09-27 N1 - Date created - 1990-09-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-17 ER - TY - JOUR T1 - Intestinal transit time as an important factor in the pathogenesis of dimethyl-hydrazine-induced rat colon cancer. AN - 74452169; 233838 JF - Surgical forum AU - Baker, A R AU - Ward, J M AU - Simon, R M AU - Stinson, S F AU - Devereux, D F AD - Surgery Branch, National Cancer Institute, Bethesda, Md. Y1 - 1978 PY - 1978 DA - 1978 SP - 491 EP - 492 VL - 29 SN - 0071-8041, 0071-8041 KW - Dimethylhydrazines KW - 0 KW - Index Medicus KW - Rats KW - Animals KW - Rats, Inbred F344 KW - Male KW - Dietary Fiber -- pharmacology KW - Colonic Neoplasms -- etiology KW - Gastrointestinal Transit UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/74452169?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Surgical+forum&rft.atitle=Intestinal+transit+time+as+an+important+factor+in+the+pathogenesis+of+dimethyl-hydrazine-induced+rat+colon+cancer.&rft.au=Baker%2C+A+R%3BWard%2C+J+M%3BSimon%2C+R+M%3BStinson%2C+S+F%3BDevereux%2C+D+F&rft.aulast=Baker&rft.aufirst=A&rft.date=1978-01-01&rft.volume=29&rft.issue=&rft.spage=491&rft.isbn=&rft.btitle=&rft.title=Surgical+forum&rft.issn=00718041&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1990-02-26 N1 - Date created - 1990-02-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-17 ER - TY - JOUR T1 - Some Statistical Considerations in Water Quality Control AN - 19178594; 7910132 AB - Some statistical aspects of water sampling are explored. Analyses are presented based on the membrane filter method and the assumption that coliform indicators are valuable. Three topics are investigated: how many samples per month are necessary for various size towns, how large should each sample be, and are the present sampling rules (based on the interim regulations of December 25, 1976) well defined. A model is presented of bacterial distribution. Also, historical data regarding the level of waterborne disease by community size are considered. (See also W79-10127) (Small-FRC) JF - Evaluation of the Microbiology Standards for Drinking Water. Report EPA-570/9-78-00C. p 49-55. 1978. 3 fig. AU - Muenz, L AD - National Institutes of Health Bethesda, MD Y1 - 1978 PY - 1978 DA - 1978 KW - Water Resources Abstracts KW - Statistical models KW - Sampling KW - Coliforms KW - Bioindicators KW - Public health KW - Water treatment KW - Diseases KW - Analytical methods KW - Regulation KW - SW 3060:Water treatment and distribution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19178594?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=Some+Statistical+Considerations+in+Water+Quality+Control&rft.au=Muenz%2C+L&rft.aulast=Muenz&rft.aufirst=L&rft.date=1978-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - EMIC: a centralized source of chemical mutagenesis information AN - 13911477; S198001141 AB - The facilities, information gathering and publication activities of the Environmental Mutagen Information Centre (EMIC) at the Oak Ridge National Laboratory, U.S.A. are reviewed. In addition to information storage and retrieval on mutagenesis, it now publishes regular reviews of the literature relating to mutagenic activity, testing procedures and public health aspects. Other services available on request are detailed by the author. JF - Environmental Health Perspectives AU - Shelby, MD AD - NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES Y1 - 1978 PY - 1978 DA - 1978 SP - 21 EP - 25 VL - 27 SN - 0091-6765, 0091-6765 KW - Environmental mutagen information centre KW - Oak ridge national laboratory, tenn KW - Aqualine Abstracts KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/13911477?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=EMIC%3A+a+centralized+source+of+chemical+mutagenesis+information&rft.au=Shelby%2C+MD&rft.aulast=Shelby&rft.aufirst=MD&rft.date=1978-01-01&rft.volume=27&rft.issue=&rft.spage=21&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2000-09-01 N1 - Last updated - 2011-12-12 ER - TY - JOUR T1 - Evolution of primate oncornaviruses: An endogenous virus from langurs (Presbytis spp.) with related virogene sequences in other Old World monkeys. AN - 733496785; 16592456 AB - Gene sequences related to a retrovirus (oncornavirus type D) isolated from a lung cell culture from spectacled langur (Presbytis obscurus) are found in multiple copies (20-40 per haploid genome) in langur cellular DNA; partially homologous virogene sequences are present in the DNA of related Old World monkey species. Primates thus contain gene sequences for at least two distinct classes of genetically transmitted oncornaviruses, the type C class (isolated from baboons) and the type D class described here. The langur virus is partially related to Mason-Pfizer monkey virus, a type D retrovirus isolated from rhesus monkeys. Nucleic acid hybridization studies suggest that Mason-Pfizer monkey virus, now infectious among primates, was derived from an endogenous virus of langurs or from another member of the primate sub-family Colobinae. JF - Proceedings of the National Academy of Sciences of the United States of America AU - Benveniste, R E AU - Todaro, G J AD - Laboratory of Viral Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014. Y1 - 1977/10// PY - 1977 DA - October 1977 SP - 4557 EP - 4561 VL - 74 IS - 10 SN - 0027-8424, 0027-8424 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733496785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Evolution+of+primate+oncornaviruses%3A+An+endogenous+virus+from+langurs+%28Presbytis+spp.%29+with+related+virogene+sequences+in+other+Old+World+monkeys.&rft.au=Benveniste%2C+R+E%3BTodaro%2C+G+J&rft.aulast=Benveniste&rft.aufirst=R&rft.date=1977-10-01&rft.volume=74&rft.issue=10&rft.spage=4557&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.issn=00278424&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-06-29 N1 - Date created - 2010-06-29 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Virol. 1977 Mar;21(3):849-62 [66330] In Vitro. 1976 Oct;12(10):665-9 [190163] J Virol. 1977 Jul;23(1):36-43 [407372] Cancer Res. 1970 Aug;30(8):2081-6 [4195910] Proc Natl Acad Sci U S A. 1974 Nov;71(11):4513-8 [4373709] Virology. 1974 Mar;58(1):65-74 [4132403] Nat New Biol. 1972 Jan 5;235(53):3-6 [4111969] Nat New Biol. 1973 Jul 11;244(132):62-4 [4352703] Nat New Biol. 1973 Jul 11;244(132):59-62 [4352702] Biochemistry. 1974 Mar 26;13(7):1549-54 [4362227] Virology. 1973 May;53(1):142-51 [4122424] J Virol. 1973 Jun;11(6):978-85 [4123287] Virology. 1973 Feb;51(2):370-82 [4120907] Nature. 1974 Mar 1;248(5443):17-20 [4131937] Intervirology. 1973;1(5):399-404 [4131819] Int J Cancer. 1974 Dec 15;14(6):722-30 [4142786] J Virol. 1974 Jul;14(1):56-67 [4365323] Nature. 1974 Dec 6;252(5483):456-9 [4372546] Nature. 1974 Nov 8;252(5479):170-3 [4371148] Virology. 1974 Apr;58(2):568-75 [4362434] Proc Natl Acad Sci U S A. 1973 Dec;70(12):3316-20 [4357865] J Natl Cancer Inst. 1973 Nov;51(5):1417-23 [4357758] Virology. 1976 Jul 1;72(1):278-82 [59458] In Vitro. 1973 Mar-Apr;8(5):333-41 [4633070] Proc Natl Acad Sci U S A. 1975 Jun;72(6):2315-9 [49058] Proc Natl Acad Sci U S A. 1974 May;71(5):1705-9 [4525459] Nature. 1976 May 13;261(5556):101-8 [179013] Int J Cancer. 1974 Feb 15;13(2):246-53 [4817575] Q Rev Biophys. 1970 Aug;3(3):327-75 [4989149] Science. 1968 Aug 9;161(3841):529-40 [4874239] J Virol. 1976 Mar;17(3):705-12 [943573] J Virol. 1977 Jan;21(1):168-78 [64624] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Stilboestrol (diethylstilbestrol) and the risk of ovarian cancer. AN - 83857571; 95735 AB - A follow-up survey of 908 women who had received 'Premarin' (conjugated equine oestrogen) for menopausal symptoms revealed 8 cases of ovarian cancer. This risk was 2 to 3 times greater than expected. The risk increased with the strength of premarin tablet usually taken, but not with the duration of use or total dose ingested. The excess risk of ovarian cancer in this group occurred primarily among 21 women who had also used stilboestrol (diethylstilbestrol). The results of this small trial are consistent with the increasing incidence of ovarian cancer in post-menopausal women in the U.S.A., and with the occurrence of stilboestrol-induced ovarian neoplasms in dogs. JF - Lancet (London, England) AU - Hoover, R AU - Gray, L A AU - Fraumeni, J F AD - Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20014. Y1 - 1977/09/10/ PY - 1977 DA - 1977 Sep 10 SP - 533 EP - 534 VL - 2 IS - 8037 SN - 0140-6736, 0140-6736 KW - Estrogens, Conjugated (USP) KW - 0 KW - Diethylstilbestrol KW - 731DCA35BT KW - Abridged Index Medicus KW - Index Medicus KW - Cocarcinogenesis KW - Dose-Response Relationship, Drug KW - Risk Factors KW - Humans KW - Confidence Intervals KW - Follow-Up Studies KW - Time Factors KW - Female KW - Estrogens, Conjugated (USP) -- therapeutic use KW - Diethylstilbestrol -- adverse effects KW - Estrogens, Conjugated (USP) -- administration & dosage KW - Ovarian Neoplasms -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/83857571?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet+%28London%2C+England%29&rft.atitle=Stilboestrol+%28diethylstilbestrol%29+and+the+risk+of+ovarian+cancer.&rft.au=Hoover%2C+R%3BGray%2C+L+A%3BFraumeni%2C+J+F&rft.aulast=Hoover&rft.aufirst=R&rft.date=1977-09-10&rft.volume=2&rft.issue=8037&rft.spage=533&rft.isbn=&rft.btitle=&rft.title=Lancet+%28London%2C+England%29&rft.issn=01406736&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1992-10-26 N1 - Date created - 1992-10-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-17 ER - TY - JOUR T1 - Central auditory imperception. AN - 85197842; pmid-561280 AB - The development of clinically applicable techniques for the evaluation of hearing impairment caused by lesions of the central auditory pathways has increased clinical interest in the anatomy and physiology of these pathways. A conceptualization of present understanding of the anatomy and physiology of the central auditory pathways is presented. Clinical tests based on reduction of redundancy of the speech message, degradation of speech and binaural interations are presented. Specifically performance-intensity functions, filtered speech tests, competing message tests and time-compressed speech tests are presented with the emphasis on our experience with time-compressed speech tests. With proper use of these tests not only can central auditory impairments by detected, but brain stem lesions can be distinguished from cortical lesions. JF - The Laryngoscope AU - Snow, J B AU - Rintelmann, W F AU - Miller, J M AU - Konkle, D F AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1977 SP - 1450 EP - 1471 VL - 87 IS - 9 Pt 1 SN - 0023-852X, 0023-852X KW - Auditory Cortex KW - Cochlea KW - Auditory Pathways KW - Auditory Threshold KW - Human KW - Animal KW - Central Nervous System KW - Electric Stimulation KW - Vestibulocochlear Nerve KW - Discrimination (Psychology) KW - Neurons KW - Hearing Tests KW - Hearing KW - Speech KW - Perceptual Disorders KW - Auditory Perception UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85197842?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Central+auditory+imperception.&rft.au=Snow%2C+J+B%3BRintelmann%2C+W+F%3BMiller%2C+J+M%3BKonkle%2C+D+F&rft.aulast=Snow&rft.aufirst=J&rft.date=1977-09-01&rft.volume=87&rft.issue=9+Pt+1&rft.spage=1450&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Neoplasms of the nasopharynx in children. AN - 85198818; pmid-193080 AB - Neoplasms of the nasopharynx are rare in children, but they threaten the child's life when they do occur. The nasopharynx tends to harbor dysontogenetic neoplasms. After classification into benign and malignant groups, nasopharyngeal neoplasms in children can be further characterized according to the age of the patients in which the clinical manifestations usually appear. Dermoids and teratomas are the most frequently encountered neoplasms of the nasopharynx in infants and may produce airway obstruction and dysphagia. Among the benign tumors of the nasopharynx in children, the juvenile angiofibroma deserves the most attention. With the onset in puberty, these neoplasms may cause recurrent massive bleeding and orbital and intracranial complications. Evaluation of the extent of the neoplasm and the source of the blood supply has been improved with bilateral selective internal and external carotid angiography. Intracranial and orbital invasion is regarded as an indication for radiotherapy. Surgery has been made somewhat safer by preoperative estrogen therapy and angiographic embolization of the major arterial supply. Patients with squamous cell carcinoma of the nasopharynx have immunologic similarities to patients with Burkitt's lymphomia and infectious mononucleosis; The etiologic role of the Epstein-Barr virus is considered. The parts played by radiation therapy, surgery, chemotherapy, and cryosurgery in the treatment of children with carcinoma of the nasopharynx are discussed. The value of radical neck dissection after radiation therapy is critically reviewed. The prognosis in patients with carcinoma of the nasopharynx is better in females than in males and better in children than in adults. JF - Otolaryngologic Clinics of North America AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1977 SP - 11 EP - 24 VL - 10 IS - 1 SN - 0030-6665, 0030-6665 KW - Infant KW - Carotid Arteries KW - Age Factors KW - Sex Factors KW - Human KW - Prognosis KW - Airway Obstruction KW - Child KW - Adolescent KW - Male KW - Female KW - Child, Preschool KW - Dermoid Cyst KW - Dermatofibroma KW - Carcinoma, Squamous Cell KW - Teratoma KW - Nasopharyngeal Neoplasms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85198818?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Otolaryngologic+Clinics+of+North+America&rft.atitle=Neoplasms+of+the+nasopharynx+in+children.&rft.au=Snow%2C+J+B&rft.aulast=Snow&rft.aufirst=J&rft.date=1977-02-01&rft.volume=10&rft.issue=1&rft.spage=11&rft.isbn=&rft.btitle=&rft.title=Otolaryngologic+Clinics+of+North+America&rft.issn=00306665&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - A method for determining cortical auditory thresholds in guinea pigs. AN - 85177792; pmid-842319 AB - A method for measuring evoked cortical potentials to acoustic stimuli through the intact dura mater of the guinea pig without computer averaging studied. After exposure of the dura overlying the auditory cortex on the left side, thresholds to acoustic stimuli presented to the right ear were determined with a double tipped silver electrode by visual detection on an oscilloscope. The thresholds obtained are compared with other methods of determining audibility levels in the guinea pig. With relatively simple instrumentation, this method provides rapid and accurate determination of the audibility curve. JF - Acta Oto-Laryngologica AU - Makishima, K AU - Keane, W M AU - Katz, R B AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1977 SP - 182 EP - 186 VL - 83 IS - 1-2 SN - 0001-6489, 0001-6489 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85177792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+Oto-Laryngologica&rft.atitle=A+method+for+determining+cortical+auditory+thresholds+in+guinea+pigs.&rft.au=Makishima%2C+K%3BKeane%2C+W+M%3BKatz%2C+R+B%3BSnow%2C+J+B&rft.aulast=Makishima&rft.aufirst=K&rft.date=1977-01-01&rft.volume=83&rft.issue=1-2&rft.spage=182&rft.isbn=&rft.btitle=&rft.title=Acta+Oto-Laryngologica&rft.issn=00016489&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Parties and Voters in the Portuguese Revolution: the Elections of 1975 and 1976 AN - 60821012; 79K3225 AB - Examined are the background & development of political parties in Portugal, especially since the Apr 1974 coup; & considered, & analyzed are the Constituent Assembly election of 25 Apr 1975, the election for the Assembly of the Republic of 25 Apr 1976, & the Presidential Election of 27 June 1976. The parties faced a "virgin electorate" -- the 1975 elections were the first ever held in free conditions on the basis of universal suffrage. Nevertheless, the four largest parties all represented important & long-standing political traditions, & these were reflected to a remarkable degree in the distribution of votes in 1975 & 1976, when in spite of the revolutionary upheaval, party shares of the poll changed to a smaller extent than might have been expected. However, the votes of the center parties -- the Socialists & the Social Democrats -- are most vulnerable in the future, because their social bases are less firm than those of the Communists or the conservative Centre Social Democrats. AA. JF - Parliamentary Affairs AU - Pimlott, Ben AD - U Newcastle Upon Tyne, NEI 7RU England Y1 - 1977/01// PY - 1977 DA - January 1977 SP - 35 EP - 58 VL - 30 IS - 1 SN - 0031-2290, 0031-2290 KW - Portugal, elections, 1975, 1976 KW - political party background/development KW - Portugal/Portuguese KW - Election/Elections KW - Political/Politically/ Politicalization (see also Politics) KW - Party/Parties KW - article KW - 0925: political interactions; political sociology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60821012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Parliamentary+Affairs&rft.atitle=Parties+and+Voters+in+the+Portuguese+Revolution%3A+the+Elections+of+1975+and+1976&rft.au=Pimlott%2C+Ben&rft.aulast=Pimlott&rft.aufirst=Ben&rft.date=1977-01-01&rft.volume=30&rft.issue=1&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=Parliamentary+Affairs&rft.issn=00312290&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - PLAFAL N1 - SubjectsTermNotLitGenreText - Portugal/Portuguese; Election/Elections; Political/Politically/ Politicalization (see also Politics); Party/Parties ER - TY - JOUR T1 - A rationale for the design of cell-specific toxic agents: the mechanism of action of 6-hydroxydopamine. AN - 83792845; 16386028 JF - FEBS letters AU - Rotman, A AU - Creveling, C R AD - National Institute of Arthritis, Metabolism and Digestive Diseases, National Institutes of Health, Bethesda. Maryland 20014, USA. Y1 - 1976/12/31/ PY - 1976 DA - 1976 Dec 31 SP - 227 EP - 230 VL - 72 IS - 2 SN - 0014-5793, 0014-5793 KW - Sympatholytics KW - 0 KW - Oxidopamine KW - 8HW4YBZ748 KW - Index Medicus KW - Animals KW - Oxidation-Reduction -- drug effects KW - Humans KW - Biological Transport -- drug effects KW - Sympatholytics -- toxicity KW - Sympatholytics -- pharmacology KW - Neurons -- metabolism KW - Oxidopamine -- toxicity KW - Oxidopamine -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/83792845?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEBS+letters&rft.atitle=A+rationale+for+the+design+of+cell-specific+toxic+agents%3A+the+mechanism+of+action+of+6-hydroxydopamine.&rft.au=Rotman%2C+A%3BCreveling%2C+C+R&rft.aulast=Rotman&rft.aufirst=A&rft.date=1976-12-31&rft.volume=72&rft.issue=2&rft.spage=227&rft.isbn=&rft.btitle=&rft.title=FEBS+letters&rft.issn=00145793&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-01-26 N1 - Date created - 2006-01-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hearing loss of a central type secondary to anoxic anoxia. AN - 85171818; pmid-999146 AB - The effect of anoxic anoxia on the threshold sensitivity and amplitude of the responses from the auditory cortex, inferior colliculus and cochlea to acoustic stimuli in guinea pigs was studied. Decay of the amplitude of the responses from the auditory cortex and the inferior colliculus occurs faster and is more severe than that of the cochlea. Recovery of the amplitude of the responses is slower at the auditory cortex and the inferior colliculus than at the cochlea. Loss of auditory threshold sensitivity in anoxic anoxia is most prominent at the auditory cortex. The loss of sensitivity at the inferior colliculus is the next most severe. The loss of sensitivity at the cochlea is negligible. The relative vulnerability of the central auditory pathway to anoxic anoxia as compared to the end organ is demonstrated. JF - The Annals of Otology, Rhinology, and Laryngology AU - Makishima, K AU - Katz, R B AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1976 SP - 826 EP - 832 VL - 85 IS - 6 PT. 1 SN - 0003-4894, 0003-4894 KW - Auditory Cortex KW - Animals KW - Deafness KW - Inferior Colliculus KW - Comparative Study KW - Guinea Pigs KW - Auditory Threshold KW - Central Nervous System Diseases KW - Electrophysiology KW - Labyrinth Diseases KW - Anoxia KW - Cochlea KW - Auditory Pathways UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85171818?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Hearing+loss+of+a+central+type+secondary+to+anoxic+anoxia.&rft.au=Makishima%2C+K%3BKatz%2C+R+B%3BSnow%2C+J+B&rft.aulast=Makishima&rft.aufirst=K&rft.date=1976-11-01&rft.volume=85&rft.issue=6+PT.+1&rft.spage=826&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Recombinant DNA research guidelines: draft environmental impact statement. AN - 83250644; 11663693 JF - Federal register AU - U.S. National Institutes of Health AD - U.S. National Institutes of Health Y1 - 1976/09/09/ PY - 1976 DA - 1976 Sep 09 SP - 38426 EP - 38483 VL - 41 IS - 176 SN - 0097-6326, 0097-6326 KW - DNA, Recombinant KW - 0 KW - Hazardous Substances KW - Bioethics KW - NIH Guidelines KW - Ecology KW - Risk KW - Government KW - Social Change KW - Reference Standards KW - Economics KW - Guidelines as Topic KW - Federal Government KW - Public Policy KW - Risk Assessment KW - Government Regulation KW - Social Control, Formal KW - Containment of Biohazards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/83250644?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Federal+register&rft.atitle=Recombinant+DNA+research+guidelines%3A+draft+environmental+impact+statement.&rft.au=U.S.+National+Institutes+of+Health&rft.aulast=U.S.+National+Institutes+of+Health&rft.aufirst=&rft.date=1976-09-09&rft.volume=41&rft.issue=176&rft.spage=38426&rft.isbn=&rft.btitle=&rft.title=Federal+register&rft.issn=00976326&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1979-04-01 N1 - Date created - 1979-04-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Histopathologic correlates of otoneurologic manifestations following head trauma. AN - 85188748; pmid-957842 AB - The clinical course of patients dying of head trauma and the physiologic evaluation of audition in guinea pigs subjected to several forms of head trauma are correlated with the histopathologic findings in the brains and temporal bones. In the patients there was wide spread hemorrhage, edema, disorganization and disruption of neural tissue. Loss of Purkinje cells and other neural elements was prominent. The temporal bone findings in the patients included laceration of and hemorrhage into the VIIIth nerve as well as bleeding into the scala tympani. The membranous labyrinths demonstrated no specific changes secondary to the trauma. The guinea pigs developed a central form of hearing loss with elevated thresholds for evoked responses from the inferior colliculus and normal AC cochlear potentials. In the animals hemorrhage in the substance of the brain, necrosis of neural tissue, edema, disorganization and disruption were prominent. Although there was extravasation of blood in the tympanic and vestibular scalae, the membranous structures of the inner ears were well preserved. JF - The Laryngoscope AU - Makishima, K AU - Sobel, S F AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1976 SP - 1303 EP - 1314 VL - 86 IS - 9 SN - 0023-852X, 0023-852X KW - Craniocerebral Trauma KW - Labyrinth KW - Support, U.S. Gov't, P.H.S. KW - Auditory Threshold KW - Guinea Pigs KW - Human KW - Animal KW - Brain KW - Aged KW - Disease Models, Animal KW - Ear KW - Vestibulocochlear Nerve KW - Adult KW - Temporal Lobe KW - Middle Age KW - Adolescent KW - Temporal Bone KW - Female KW - Male KW - Occipital Lobe UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85188748?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Histopathologic+correlates+of+otoneurologic+manifestations+following+head+trauma.&rft.au=Makishima%2C+K%3BSobel%2C+S+F%3BSnow%2C+J+B&rft.aulast=Makishima&rft.aufirst=K&rft.date=1976-09-01&rft.volume=86&rft.issue=9&rft.spage=1303&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Recombinant DNA Research Guidelines. AN - 83236696; 11663674 JF - Federal register AU - U.S. National Institutes of Health AD - U.S. National Institutes of Health Y1 - 1976/07/07/ PY - 1976 DA - 1976 Jul 07 SP - 27902 EP - 27943 VL - 41 IS - 131 SN - 0097-6326, 0097-6326 KW - DNA, Recombinant KW - 0 KW - Hazardous Substances KW - Bioethics KW - National Institutes of Health KW - Risk KW - Reference Standards KW - Guidelines as Topic KW - Public Policy KW - Attitude KW - Risk Assessment KW - Government Regulation KW - Government KW - Social Control, Formal KW - National Institutes of Health (U.S.) KW - Federal Government UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/83236696?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Federal+register&rft.atitle=Recombinant+DNA+Research+Guidelines.&rft.au=U.S.+National+Institutes+of+Health&rft.aulast=U.S.+National+Institutes+of+Health&rft.aufirst=&rft.date=1976-07-07&rft.volume=41&rft.issue=131&rft.spage=27902&rft.isbn=&rft.btitle=&rft.title=Federal+register&rft.issn=00976326&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1979-04-01 N1 - Date created - 1979-04-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of head blow on the development of hearing loss. AN - 85198640; pmid-933692 AB - The effects of the direction and intensity of the head blow and the effects of the lapse of time after a head blow on the development of hearing loss were studied in guinea pigs. The electrical responses from the right inferior colliculus (ER) and from the left round window (CP) to acoustic stimuli were measured. The elevation in threshold of the ER in the presence of normal CP in guinea pigs after a head blow suggests that the site of the lesion is central to the cochlea. JF - The Laryngoscope AU - Makishima, K AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1976 SP - 971 EP - 978 VL - 86 IS - 7 SN - 0023-852X, 0023-852X KW - Craniocerebral Trauma KW - Occipital Bone KW - Hearing Disorders KW - Guinea Pigs KW - Animal KW - Hearing Tests KW - Temporal Bone KW - Time Factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85198640?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Effects+of+head+blow+on+the+development+of+hearing+loss.&rft.au=Makishima%2C+K%3BSnow%2C+J+B&rft.aulast=Makishima&rft.aufirst=K&rft.date=1976-07-01&rft.volume=86&rft.issue=7&rft.spage=971&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - An improved culture flask for photographic and visual observation of living cell cultures AN - 907169956; 15726851 AB - A new type of culture vessel is described, identical in shape to the classic T15 vessel but with the advantage of optical surfaces that allow photography at medium resolution (with numerical apertures of 0.60-1.0). Details of flask manufacture are given. JF - Journal of Microscopy (Oxford) AU - Fox, Cecil H AU - Chaconas, Peter G AU - Sanford, Katherine K AD - Cell Physiology and Oncogenesis Section, Laboratory of Biochemistry, National Cancer Institute, National Institute of Health, Bethesda, Maryland 20014, and Perpetual Systems Incorporated, 5405-F Randolph Road, Rockville, Maryland 20852, U.S.A. Y1 - 1976/05// PY - 1976 DA - May 1976 SP - 79 EP - 83 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 107 IS - 1 SN - 0022-2720, 0022-2720 KW - Biotechnology and Bioengineering Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Cell culture KW - Photography KW - W 30945:Fermentation & Cell Culture KW - Q1 08182:Methods and instruments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907169956?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microscopy+%28Oxford%29&rft.atitle=An+improved+culture+flask+for+photographic+and+visual+observation+of+living+cell+cultures&rft.au=Fox%2C+Cecil+H%3BChaconas%2C+Peter+G%3BSanford%2C+Katherine+K&rft.aulast=Fox&rft.aufirst=Cecil&rft.date=1976-05-01&rft.volume=107&rft.issue=1&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microscopy+%28Oxford%29&rft.issn=00222720&rft_id=info:doi/10.1111%2Fj.1365-2818.1976.tb02425.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Cell culture; Photography DO - http://dx.doi.org/10.1111/j.1365-2818.1976.tb02425.x ER - TY - JOUR T1 - DISCUSSION OF PART VIII: METHODOLOGIES FOR RISK ASSESSMENT AN - 867746826; 14668684 JF - Annals of the New York Academy of Sciences AU - Saffiotti, Umberto AD - Division of Cancer Cause and Prevention National Cancer Institute Bethesda, Maryland 20014 Y1 - 1976/05// PY - 1976 DA - May 1976 SP - 513 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 271 IS - 1 SN - 0077-8923, 0077-8923 KW - Risk Abstracts KW - Risk assessment KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867746826?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=DISCUSSION+OF+PART+VIII%3A+METHODOLOGIES+FOR+RISK+ASSESSMENT&rft.au=Saffiotti%2C+Umberto&rft.aulast=Saffiotti&rft.aufirst=Umberto&rft.date=1976-05-01&rft.volume=271&rft.issue=1&rft.spage=513&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/10.1111%2Fj.1749-6632.1976.tb23156.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Risk assessment DO - http://dx.doi.org/10.1111/j.1749-6632.1976.tb23156.x ER - TY - JOUR T1 - STATISTICAL EXTRAPOLATION METHODS FOR ESTIMATING RISKS FROM ANIMAL DATA AN - 867746819; 14668681 JF - Annals of the New York Academy of Sciences AU - Hoel, David G AD - National Institute of Environmental Health Sciences National Institutes of Health Research Triangle Park, North Carolina 27709 Y1 - 1976/05// PY - 1976 DA - May 1976 SP - 418 EP - 420 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 271 IS - 1 SN - 0077-8923, 0077-8923 KW - Risk Abstracts KW - Animals KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867746819?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=STATISTICAL+EXTRAPOLATION+METHODS+FOR+ESTIMATING+RISKS+FROM+ANIMAL+DATA&rft.au=Hoel%2C+David+G&rft.aulast=Hoel&rft.aufirst=David&rft.date=1976-05-01&rft.volume=271&rft.issue=1&rft.spage=418&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/10.1111%2Fj.1749-6632.1976.tb23142.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Number of references - 5 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Animals DO - http://dx.doi.org/10.1111/j.1749-6632.1976.tb23142.x ER - TY - JOUR T1 - GEOGRAPHIC PATTERNS OF CANCER RISK: A MEANS FOR IDENTIFYING POSSIBLE OCCUPATIONAL FACTORS AN - 867745301; 14668703 JF - Annals of the New York Academy of Sciences AU - Mason, Thomas J AD - Epidemiology Branch National Cancer Institute Bethesda, Maryland 20014 Y1 - 1976/05// PY - 1976 DA - May 1976 SP - 370 EP - 376 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 271 IS - 1 SN - 0077-8923, 0077-8923 KW - Risk Abstracts KW - Cancer KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867745301?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=GEOGRAPHIC+PATTERNS+OF+CANCER+RISK%3A+A+MEANS+FOR+IDENTIFYING+POSSIBLE+OCCUPATIONAL+FACTORS&rft.au=Mason%2C+Thomas+J&rft.aulast=Mason&rft.aufirst=Thomas&rft.date=1976-05-01&rft.volume=271&rft.issue=1&rft.spage=370&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/10.1111%2Fj.1749-6632.1976.tb23133.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Number of references - 6 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Cancer DO - http://dx.doi.org/10.1111/j.1749-6632.1976.tb23133.x ER - TY - JOUR T1 - Electrophysiological responses from the cochlea and inferior colliculus in guinea pigs after head injury. AN - 85192967; pmid-1202302 AB - Electrical responses from the inferior colliculus (ER) and round window (CP) to acoustical stimuli were compared in control and experimental guinea pigs which had received a single blow to the freely movable head. After the blow to the head, all of the animals showed signs of commotio cerebri, and some of them died. The experimental animals were divided into two groups so that the physiologic responses to sound could be evaluated one day (early group) and seven days (intermediate group) following the head blow. The animals of the early group had elevated ER thresholds over the entire frequency range tested with an average threshold of 37.8 db. The animals of the intermediate group also had elevated ER thresholds which averaged 23.9 db. Input-output intensity function of ER for the experimental animals showed a recruitment-like phenomenon. The CP thresholds in the injured animals did not differ significantly from those in the control group. Damage to the VIIIth nerve and higher central pathways is very likely a more frequent cause of the otoneurologic manifestations following head injury than end organ damage. JF - The Laryngoscope AU - Makishima, K AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1975 SP - 1947 EP - 1957 VL - 85 IS - 12 pt 1 SN - 0023-852X, 0023-852X KW - Cochlea KW - Craniocerebral Trauma KW - Inferior Colliculus KW - Support, U.S. Gov't, P.H.S. KW - Guinea Pigs KW - Vestibular Nerve KW - Animal KW - Action Potentials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85192967?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Electrophysiological+responses+from+the+cochlea+and+inferior+colliculus+in+guinea+pigs+after+head+injury.&rft.au=Makishima%2C+K%3BSnow%2C+J+B&rft.aulast=Makishima&rft.aufirst=K&rft.date=1975-12-01&rft.volume=85&rft.issue=12+pt+1&rft.spage=1947&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Carcinoma of the nasopharynx in children. AN - 85180019; pmid-173235 AB - Seven children with carcinoma of the nasopharynx have been treated and followed for five years. In this group of patients there were no cranial nerve palsies or radiographic evidence of destruction of the base of the skull. Four of the seven patients are living and well. The development of lymphoepithelioma in two siblings is of great interest from an environmental and genetic point of view. The older sibling developed the clinical manifestations of the tumor at 12 years of age and four years later the younger sibling developed them at 14 years of age. The possible etiologic relationship of carcinoma of the nasopharynx to the Epstein-Barr virus is discussed. The good survival rate in these patients under 21 years of age suggests that the prognosis in carcinoma of the nasopharynx is better in the younger age group than in adults. The management of these patients illustrates that carcinoma of the nasopharynx should be managed as a regional rather than a systemic disease. Systemic drug therapy is sometimes advocated because of confusion over the name lymphoepithelioma on the assumption that these tumors are more related to lymphomas and lymphosarcomas than carcinomas. It is clear that lymphoepitheliomas should be managed as carcinomas. JF - The Annals of Otology, Rhinology, and Laryngology AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1975 SP - 817 EP - 826 VL - 84 IS - 6 SN - 0003-4894, 0003-4894 KW - Animals KW - Diagnosis, Differential KW - Humans KW - Prognosis KW - Child KW - Carcinogens KW - Cryosurgery KW - Herpesvirus 4, Human KW - Carcinoma KW - Oklahoma KW - Adult KW - Neoplasm Metastasis KW - Sarcoma KW - Middle Aged KW - Adolescent KW - Lymphoma KW - Female KW - China KW - Male KW - Nasopharyngeal Neoplasms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85180019?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Carcinoma+of+the+nasopharynx+in+children.&rft.au=Snow%2C+J+B&rft.aulast=Snow&rft.aufirst=J&rft.date=1975-11-01&rft.volume=84&rft.issue=6&rft.spage=817&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Pathologic features of the inner ear in congenital deafness. AN - 85246567; pmid-1164223 AB - We present the morphologic findings of the temporal bones and brain of a patient with congenital deafness. We discuss these findings in relation to pathologic observations in other reported cases of congenital deafness. Morphologic abnormalities in the patient were mainly in the pars inferior of the membranous labyrinths. The osseous labyrinths were well developed. There was severe dilation of the cochlear duct with herniation of the Reissner membrane, extensive atrophy of the stria vascularis that was associated with calcified thrombi to the strial vessels, encasement of the tectorial membrane in a syncytium, and dyspiastic or regressive degeneration of the organ of Corti. Absence of spiral ganglion cells and their fibers was a prominent feature. The extensive and varied pathologic changes that were present in our patient simultaneously suggest a congenital abnormality in endolymph production and raise the possibility of anomalous development of the labyrinthine vasculature. JF - Archives of Otolaryngology (Chicago, Ill. : 1960) AU - Makishima, K AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1975 SP - 600 EP - 604 VL - 101 IS - 10 SN - 0003-9977, 0003-9977 KW - Cochlea KW - Labyrinth KW - Deafness KW - Endolymph KW - Human KW - Aged KW - Case Report KW - Temporal Bone KW - Female UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85246567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.atitle=Pathologic+features+of+the+inner+ear+in+congenital+deafness.&rft.au=Makishima%2C+K%3BSnow%2C+J+B&rft.aulast=Makishima&rft.aufirst=K&rft.date=1975-10-01&rft.volume=101&rft.issue=10&rft.spage=600&rft.isbn=&rft.btitle=&rft.title=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.issn=00039977&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Evoked responses from inferior colliculus as an index of hearing thresholds in guinea pigs. AN - 85176240; pmid-1180037 AB - Bipolar electrodes were implanted in the inferior colliculus of 10 healthy guinea pigs, and visual detection level thresholds of auditory evoked responses were obtained at 17 frequencies between 0.5 and 20.0 kHz. One microvolt isopotential curves from the round window for the same test frequencies were obtained in these animals. A comparison between the evoked response threshold curves and previous reports of the behavioral audiogram reveals a favorable correlation. The cochlear potential curve, however, appears to be a less efficient predictor of the audibility curve than the evoked response thresholds. The utility of evoked response audiometry from the inferior colliculus for quickly assessing auditory thresholds in the guinea pig is discussed. JF - Acta Oto-Laryngologica AU - Makishima, K AU - Saunders, J C AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1975 SP - 238 EP - 244 VL - 80 IS - 3-4 SN - 0001-6489, 0001-6489 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85176240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+Oto-Laryngologica&rft.atitle=Evoked+responses+from+inferior+colliculus+as+an+index+of+hearing+thresholds+in+guinea+pigs.&rft.au=Makishima%2C+K%3BSaunders%2C+J+C%3BSnow%2C+J+B&rft.aulast=Makishima&rft.aufirst=K&rft.date=1975-09-01&rft.volume=80&rft.issue=3-4&rft.spage=238&rft.isbn=&rft.btitle=&rft.title=Acta+Oto-Laryngologica&rft.issn=00016489&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Control of the microcirculation of the inner ear. AN - 85198209; pmid-1153208 AB - In general, many similarities are seen between cerebral blood flow and cochlear blood flow in response to vasodilating drugs. Cochlear vessels appear to be weakly controlled by the adrenergic nervous system. Cholinergic agents dilate cochlear vessels, although the vasodilation in the cochlea does not necessarily cause an increase in cochlear blood flow because of the associated hypotension. The effect on the systemic circulation is too profound to make these agents clinically useful. Papaverine, dipyridamole, amyl nitrite, and the plasma kinins produce transient increases in cochlear blood flow. Ten per cent carbon dioxide and 90 per cent oxygen product progressive vasodilation as long as the mixture is inhaled. Hydralazine produces too profound an effect on systemic blood pressure. Histamine and betahistine increase cochlear blood flow but only in doses that produce bronchiospasm in the guinea pig. Nicotinic acid and nicotinyl tartrate have no effect on cochlear blood flow. If one considers safety and efficacy as well as patient tolerance, papaverine appears to be the drug of choice for increasing cochlear blood flow clinically. Histamine and betahistine appear to be acceptable alternatives. Betahistine is no longer available for clinical use because of the failure to demonstrate clinical efficacy of therapy. JF - Otolaryngologic Clinics of North America AU - Snow, J B AU - Suga, F AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1975 SP - 455 EP - 466 VL - 8 IS - 2 SN - 0030-6665, 0030-6665 KW - Cochlea KW - Labyrinth KW - Parasympathetic Nervous System KW - Vasomotor System KW - Plethysmography, Impedance KW - Sympathetic Nervous System KW - Vasodilator Agents KW - Support, U.S. Gov't, P.H.S. KW - Human KW - Histocytochemistry KW - Microcirculation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85198209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Otolaryngologic+Clinics+of+North+America&rft.atitle=Control+of+the+microcirculation+of+the+inner+ear.&rft.au=Snow%2C+J+B%3BSuga%2C+F&rft.aulast=Snow&rft.aufirst=J&rft.date=1975-06-01&rft.volume=8&rft.issue=2&rft.spage=455&rft.isbn=&rft.btitle=&rft.title=Otolaryngologic+Clinics+of+North+America&rft.issn=00306665&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Transient neutropenia induced by transfusion of blood exposed to nylon fiber filters. AN - 83355873; 803106 AB - During the course of granulocyte collection by continuous-flow filtration leukopheresis, an abrupt fall in neutrophil count was noted (mean decrease 77%, range 64%-95%). Neutropenia occurred within 5 min of return of blood exposed to the nylon fiber filters and lasted less than 30 min. Saline exposed to the fibers, withdrawal and reinfusion of whole blood, and heparin did not cause neutropenia. Heparinized blood passed by gravity through isolated filters and reinfused immediately also induced neutropenia (mean decrease 64% +/- 8%, range 11%-19%). Blood anticoagulated with ACD (decrease 19.5% +/- 6%, range 6%-56%), heparinized plasma (N = 10, decrease 15% +/- 3%, range 3%-29%) and platelet-rich plasma exposed to the filters failed to produce neutropenia. 91% +/- 2% of the neutrophils adhered to the fibers using heparinized blood as compared to 21% +/- 5% using ACD (p less than 0.001). All donors were asymptomatic during the infusions. These results suggest that during neutrophil adherence a substance is released which produces profound, transient neutropenia perhaps by inducing margination of cells. JF - Blood AU - Schiffer, C A AU - Aisner, J AU - Wiernik, P H AD - Section of Medical Oncology, NCI-Baltimore Cancer Research Center, Md 21201. Y1 - 1975/01// PY - 1975 DA - January 1975 SP - 141 EP - 146 VL - 45 IS - 1 SN - 0006-4971, 0006-4971 KW - Nylons KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - Platelet Adhesiveness KW - Filtration KW - Humans KW - Blood Donors KW - Platelet Count KW - Neutropenia -- etiology KW - Leukapheresis -- methods KW - Blood Transfusion KW - Nylons -- adverse effects KW - Agranulocytosis -- etiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/83355873?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Blood&rft.atitle=Transient+neutropenia+induced+by+transfusion+of+blood+exposed+to+nylon+fiber+filters.&rft.au=Schiffer%2C+C+A%3BAisner%2C+J%3BWiernik%2C+P+H&rft.aulast=Schiffer&rft.aufirst=C&rft.date=1975-01-01&rft.volume=45&rft.issue=1&rft.spage=141&rft.isbn=&rft.btitle=&rft.title=Blood&rft.issn=00064971&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1990-05-16 N1 - Date created - 1990-05-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-17 ER - TY - JOUR T1 - The effect of chemotherapy on the kinetics and proliferative capacity of normal and tumorous tissues in vivo. AN - 83239433; 803102 AB - The proliferative state of a given tissue is a major determinant of its sensitivity to both phase-specific and cycle-specific chemotherapeutic agents. To study the extent of injury induced by antitumor agents to normal and tumorous tissues, a technique for following DNA synthesis as reflected in the incorporation of tritiated thymidine (3H-TdR) into DNA was compared to the conventional radioautographic technique of the labeling index (LI) and to the functional kinetic technique of granulocyte colony formation in vitro. Alterations in DNA synthesis induced by a single dose of cyclophosphamide in normal and tumorous tissues in vivo paralleled in many respects the changes seen when the more time-consuming techniques of the LI or granulocyte colony formation were employed. However, the recovery of granulocyte colony formation after cyclophosphamide therapy lagged behind the recovery of DNA synthesis in the bone marrow, obscuring a kinetic event of potential therapeutic significance. The determination of DNA synthesis simultaneously in normal and tumorous tissues in vivo was easy to perform and supplied therapeutically pertinent results comparatively quickly. JF - Blood AU - Rosenoff, S H AU - Bull, J M AU - Young, R C AD - Section on Cellular Kinetics, National Cancer Institute, Bethesda 20014. Y1 - 1975/01// PY - 1975 DA - January 1975 SP - 107 EP - 118 VL - 45 IS - 1 SN - 0006-4971, 0006-4971 KW - Cyclophosphamide KW - 8N3DW7272P KW - Abridged Index Medicus KW - Index Medicus KW - Mice, Inbred Strains KW - Animals KW - Leukemia L1210 -- pathology KW - Cells, Cultured KW - Kinetics KW - Cell Division -- drug effects KW - Mice KW - Female KW - Tumor Cells, Cultured -- cytology KW - Tumor Cells, Cultured -- drug effects KW - Hematopoietic Stem Cells -- cytology KW - Cyclophosphamide -- toxicity KW - DNA Replication -- drug effects KW - Hematopoietic Stem Cells -- drug effects KW - Cyclophosphamide -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/83239433?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Blood&rft.atitle=The+effect+of+chemotherapy+on+the+kinetics+and+proliferative+capacity+of+normal+and+tumorous+tissues+in+vivo.&rft.au=Rosenoff%2C+S+H%3BBull%2C+J+M%3BYoung%2C+R+C&rft.aulast=Rosenoff&rft.aufirst=S&rft.date=1975-01-01&rft.volume=45&rft.issue=1&rft.spage=107&rft.isbn=&rft.btitle=&rft.title=Blood&rft.issn=00064971&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1990-05-16 N1 - Date created - 1990-05-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-17 ER - TY - JOUR T1 - Temporal and Masking Phenomena in Persons with Sensorineural Hearing Loss AN - 57962799; 7600736 AB - Relatively few experimental investigations have studied backward or forward masking, masking level differences, or differential frequency effects in simultaneous masking among persons with hearing impairment. This is regrettable since such efforts may lead to important new understandings of auditory processes. Available data on the subject is reviewed, some precautions of experimental procedure are discussed, & suggestions for future research directions are offered. HA JF - Audiology/Audiologie AU - Elliott, Lois L AD - Communicative Disorders C & FR National Instit Neurological Disease & Stroke The National Institutes of Health, Bethesda MD 20014 Y1 - 1975///0, PY - 1975 DA - 0, 1975 SP - 336 EP - 353 VL - 14 IS - 4 SN - 0020-6091, 0020-6091 KW - temporal, masking phenomena in sensorineural hearing loss KW - experimental precautions KW - Speech Perception (sp6) KW - Hearing Disorders (he3a) KW - Audiometry (au3) KW - Auditory Masking (au6) KW - Nervous System Pathology (ne3) KW - Frequency of Vibration (fr3) KW - Noise (no1) KW - article KW - 6310: hearing-pathological and normal; hearing-pathological and normal UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57962799?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Allba&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Audiology%2FAudiologie&rft.atitle=Temporal+and+Masking+Phenomena+in+Persons+with+Sensorineural+Hearing+Loss&rft.au=Elliott%2C+Lois+L&rft.aulast=Elliott&rft.aufirst=Lois&rft.date=1975-01-01&rft.volume=14&rft.issue=4&rft.spage=336&rft.isbn=&rft.btitle=&rft.title=Audiology%2FAudiologie&rft.issn=00206091&rft_id=info:doi/ LA - English DB - Linguistics and Language Behavior Abstracts (LLBA) N1 - Date revised - 2003-10-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AUDLAK N1 - SubjectsTermNotLitGenreText - Auditory Masking (au6); Hearing Disorders (he3a); Frequency of Vibration (fr3); Noise (no1); Speech Perception (sp6); Nervous System Pathology (ne3); Audiometry (au3) ER - TY - JOUR T1 - Mercury and iron uptake by cytosomes in mantle epithelial cells of quahog clams (Mercenaria mercenaria) exposed to mercury AN - 13940349; 197600316 AB - Quahog clams (Mercenaria mercenaria) were exposed to concentrations of 0.1, 1.0, and 10 p.p.m. mercury in sea water for 6 days. Mantle tentacle cells were then examined by light and electron microscopy, energy dispersive microanalysis, and atomic absorption spectroscopy. Cells from controls were indistinguishable from those from mercury exposed clams by light microscopy, but electron microscopy showed dense cytosomes in cells from clams exposed to 1.0 and 10 p.p.m. mercury. Energy dispersive X-ray microanalysis of these cytosomes disclosed the presence of high iron concentrations in relation to mercury. Marked changes in tissue iron levels in the mantle cells occurred in mercury exposed clams. Electron micrographs of cells, X-ray spectra of cytosomes, and results of analysis are presented. A bibliography of 19 references is appended. JF - J. Fish. Res. Bd Canada AU - Fowler, BA AU - Wolfe, DA AU - Hettler, W F AD - U.S. National Institute of Environmental Health Sciences Y1 - 1975 PY - 1975 DA - 1975 SP - 1767 EP - 1775 VL - 32 IS - 10 KW - Analysis KW - Mantle KW - Sea water (see also marine -----) KW - Aqualine Abstracts KW - AQ:00000 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/13940349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=J.+Fish.+Res.+Bd+Canada&rft.atitle=Mercury+and+iron+uptake+by+cytosomes+in+mantle+epithelial+cells+of+quahog+clams+%28Mercenaria+mercenaria%29+exposed+to+mercury&rft.au=Fowler%2C+BA%3BWolfe%2C+DA%3BHettler%2C+W+F&rft.aulast=Fowler&rft.aufirst=BA&rft.date=1975-01-01&rft.volume=32&rft.issue=10&rft.spage=1767&rft.isbn=&rft.btitle=&rft.title=J.+Fish.+Res.+Bd+Canada&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2000-09-01 N1 - Last updated - 2011-12-12 ER - TY - JOUR T1 - Brain metabolite concentrations and redox states in rats fed diets containing 1,3-butanediol and ethanol. AN - 82774697; 4283684 JF - Toxicology and applied pharmacology AU - Veech, R L AU - Harris, R L AU - Mehlman, M A AD - National Institute of Mental Health, Saint Elizabeth's Hospital, Washington, D.C. Y1 - 1974/08// PY - 1974 DA - August 1974 SP - 196 EP - 203 VL - 29 IS - 2 SN - 0041-008X, 0041-008X KW - Butylene Glycols KW - 0 KW - Ethanol KW - 3K9958V90M KW - Index Medicus KW - Rats, Inbred Strains KW - Rats KW - Oxidation-Reduction KW - Animals KW - Diet KW - Male KW - Butylene Glycols -- toxicity KW - Brain Chemistry -- drug effects KW - Ethanol -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/82774697?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Brain+metabolite+concentrations+and+redox+states+in+rats+fed+diets+containing+1%2C3-butanediol+and+ethanol.&rft.au=Veech%2C+R+L%3BHarris%2C+R+L%3BMehlman%2C+M+A&rft.aulast=Veech&rft.aufirst=R&rft.date=1974-08-01&rft.volume=29&rft.issue=2&rft.spage=196&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 1992-03-04 N1 - Date created - 1992-03-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-17 ER - TY - JOUR T1 - Pathology of Stomach Cancer in Rats and Mice Induced with the Agricultural Chemicals Ethylene Dibromide and Dibromochloropropane AN - 755137310; 13645427 JF - Toxicologic Pathology AU - Ward, J M AU - Habermann, R T AD - National Cancer Institute, NIH, Bethesda, MD, Hazelton Laboratories, Vienna, VA Y1 - 1974/06// PY - 1974 DA - Jun 1974 SP - 10 EP - 11 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 2 IS - 2 SN - 0192-6233, 0192-6233 KW - Toxicology Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/755137310?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+Pathology&rft.atitle=Pathology+of+Stomach+Cancer+in+Rats+and+Mice+Induced+with+the+Agricultural+Chemicals+Ethylene+Dibromide+and+Dibromochloropropane&rft.au=Ward%2C+J+M%3BHabermann%2C+R+T&rft.aulast=Ward&rft.aufirst=J&rft.date=1974-06-01&rft.volume=2&rft.issue=2&rft.spage=10&rft.isbn=&rft.btitle=&rft.title=Toxicologic+Pathology&rft.issn=01926233&rft_id=info:doi/10.1177%2F019262337400200203 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2012-03-29 DO - http://dx.doi.org/10.1177/019262337400200203 ER - TY - JOUR T1 - Metazoan Parasites of Nonhuman Primates AN - 755137298; 13645422 JF - Toxicologic Pathology AU - Whitney, Robert A AD - Veterinary Resources Branch Division of Research Services National Institutes of Health Bethesda, Maryland 20014 Y1 - 1974/03// PY - 1974 DA - Mar 1974 SP - 15 EP - 19 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 2 IS - 1 SN - 0192-6233, 0192-6233 KW - Toxicology Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/755137298?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+Pathology&rft.atitle=Metazoan+Parasites+of+Nonhuman+Primates&rft.au=Whitney%2C+Robert+A&rft.aulast=Whitney&rft.aufirst=Robert&rft.date=1974-03-01&rft.volume=2&rft.issue=1&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Toxicologic+Pathology&rft.issn=01926233&rft_id=info:doi/10.1177%2F019262337400200106 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2012-03-29 DO - http://dx.doi.org/10.1177/019262337400200106 ER - TY - JOUR T1 - An in vitro model of gluten-sensitive enteropathy. Effect of gliadin on intestinal epithelial cells of patients with gluten-sensitive enteropathy in organ culture. AN - 82268135; 11344562 AB - Jejunal biopsy specimens from patients with gluten-sensitive enteropathy (GSE) (obtained during gluten challenge) as well as from normal individuals and patients with other gastrointestinal abnormalities were cultured in vitro for 48 h in the presence or absence of a peptic-tryptic digest (P-T digest) of gliadin. In the absence of gliadin the alkaline phosphatase activity in the biopsy specimens obtained from normal control individuals increased from an initial value of 384 +/- 83 U to a 48 h value of 561 +/- 151 U (mean +/- SD) (difference significant at P < 0.01). The initial alkaline phosphatase activity of specimens obtained from patients with GSE was strikingly lower than that of normals, 117 +/- 79 U, and increased to a 48 h value of 399 +/- 203 U (difference significant at P < 0.01). The biochemical change in cultured biopsy specimens of GSE patients correlated with increases in the length and regularity of brush borders of epithelial cells as seen with the electron microscope. In the presence of a P-T digest of gliadin, the alkaline phosphatase activity of biopsy specimens of control individuals increased from an initial value of 384 +/- 83 U to a 48 h value of 578 +/- 156 U. In contrast, the alkaline phosphatase activity of biopsy specimens of patients with GSE in exacerbation showed a markedly diminished increase in activity during 48 h of culture; in this case the initial activity was 117 +/- 79 U and the final activity was 203 +/- 93 U. This inhibitory effect on increase of alkaline phosphatase activity during organ culture was specific in that a P-T digest of casein (a protein not toxic in vivo to patients with GSE) had no effect on alkaline phosphatase increases in culture. Finally, these results obtained with biopsy specimens taken from patients with GSE in exacerbation were compared with results obtained from patients with GSE in remission. Alkaline phosphatase activity of specimens obtained from the latter group of patients also increased during culture but in this instance P-T digest of gliadin in the culture medium had no significant inhibitory effect. In conclusion, the inhibitory effect of gliadin on intestinal epithelial cells in organ culture represents an in vitro model of gluten-sensitive enteropathy. Inasmuch as this effect of gliadin is not seen in cultures of specimens taken from patients in remission, it appears that gliadin is not directly toxic to GSE jejunal mucosa per se, but rather toxicity requires the participation of an endogenous effector mechanism which must first be stimulated in vivo. JF - The Journal of clinical investigation AU - Falchuk, Z M AU - Gebhard, R L AU - Sessoms, C AU - Strober, W AD - Digestive and Hereditary Diseases Branch, National Institute of Arthritis, Metabolism, and Digestive Diseases, and Metabolism Branch, Immunophysiology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014, USA. Y1 - 1974/02// PY - 1974 DA - February 1974 SP - 487 EP - 500 VL - 53 IS - 2 SN - 0021-9738, 0021-9738 KW - Glutens KW - 8002-80-0 KW - Gliadin KW - 9007-90-3 KW - Alkaline Phosphatase KW - EC 3.1.3.1 KW - Disaccharidases KW - EC 3.2.1.- KW - Abridged Index Medicus KW - Index Medicus KW - Intestinal Mucosa -- ultrastructure KW - Gastrointestinal Diseases KW - Humans KW - Disaccharidases -- metabolism KW - Aged KW - Intestinal Mucosa -- metabolism KW - Alkaline Phosphatase -- metabolism KW - Child KW - Microscopy, Electron -- methods KW - Models, Biological KW - Adult KW - Intestinal Mucosa -- pathology KW - Middle Aged KW - Adolescent KW - Organ Culture Techniques KW - Glutens -- pharmacology KW - Jejunum -- drug effects KW - Gliadin -- metabolism KW - Celiac Disease -- metabolism KW - Jejunum -- ultrastructure KW - Gliadin -- pharmacology KW - Celiac Disease -- pathology KW - Jejunum -- pathology KW - Jejunum -- metabolism KW - Glutens -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/82268135?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+clinical+investigation&rft.atitle=An+in+vitro+model+of+gluten-sensitive+enteropathy.+Effect+of+gliadin+on+intestinal+epithelial+cells+of+patients+with+gluten-sensitive+enteropathy+in+organ+culture.&rft.au=Falchuk%2C+Z+M%3BGebhard%2C+R+L%3BSessoms%2C+C%3BStrober%2C+W&rft.aulast=Falchuk&rft.aufirst=Z&rft.date=1974-02-01&rft.volume=53&rft.issue=2&rft.spage=487&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+clinical+investigation&rft.issn=00219738&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-07-19 N1 - Date created - 2001-05-09 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Clin Invest. 1969 Jan;48(1):210-28 [5765024] J Clin Invest. 1969 Aug;48(8):1423-32 [5796354] Ann N Y Acad Sci. 1969 Oct 14;166(2):447-65 [5265237] Br Med J. 1970 Oct 3;4(5726):14-7 [4919117] N Engl J Med. 1970 Dec 3;283(23):1245-50 [5476480] Gastroenterology. 1970 Oct;59(4):575-82 [5477751] Anal Biochem. 1968 Jan;22(1):99-107 [5636962] J Biol Chem. 1951 Nov;193(1):265-75 [14907713] Proc R Soc Med. 1956 Dec;49(12):1009-13 [13389464] Gastroenterology. 1959 Jul;37(1):1-16 [13663995] J Cell Biol. 1962 Mar;12:623-7 [13873575] Lancet. 1959 Sep 5;2(7097):252-5 [13824666] J Biol Chem. 1967 Feb 10;242(3):445-50 [6022842] J Clin Invest. 1971 Mar;50(3):559-69 [5101780] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Orientation on a Coordination Program On Environmental Carcinogenesis AN - 867745904; 13645413 JF - Toxicologic Pathology AU - Kraybill, H F AU - Richardson, Howard L AD - National Cancer Institute National Institutes of Health Bethesda, Maryland Y1 - 1973/12// PY - 1973 DA - Dec 1973 SP - 18 EP - 22 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 1 IS - 4 SN - 0192-6233, 0192-6233 KW - Toxicology Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867745904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+Pathology&rft.atitle=Orientation+on+a+Coordination+Program+On+Environmental+Carcinogenesis&rft.au=Kraybill%2C+H+F%3BRichardson%2C+Howard+L&rft.aulast=Kraybill&rft.aufirst=H&rft.date=1973-12-01&rft.volume=1&rft.issue=4&rft.spage=18&rft.isbn=&rft.btitle=&rft.title=Toxicologic+Pathology&rft.issn=01926233&rft_id=info:doi/10.1177%2F019262337300100406 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2012-03-29 DO - http://dx.doi.org/10.1177/019262337300100406 ER - TY - JOUR T1 - COMPUTER IDENTIFICATION OF BACTERIA ON THE BASIS OF THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERNS AN - 19070892; 7401443 AB - A COMPUTER PROGRAM UTILIZING A BAYSEAN MATHEMATICAL MODEL WAS DEVELOPED TO IDENTIFY BACTERIA SOLELY ON THE BASIS OF THEIR ANTIBIOTIC SENSITIVITIES. THE MODEL CONTAINS PROBABILITY DATA ON THE ANTIBIOTIC SENSITIVITY PATTERNS OF 31 SPECIES OF BACTERIA OF THE FOLLOWING GENERA: STAPHYLOCOCCUS, PSEUDOMONAS, KLEBSIELLA, ESCHERICHIA, PROTEUS, STREPTOCOCCUS, ENTEROBACTER, SERRATIA, CITROBACTER, BACTEROIDES, HAEMOPHILUS, BACILLUS, SALMONELLA, AND PROVIDENCE. DURING A 4-MONTH TEST PERIOD, ANTIBIOTIC SENSITIVITY DATA ON 1,000 CLINICAL ISOLATES WERE PROCESSED BY THE PROGRAM. THE IDENTIFICATION ACHIEVED BY USING THE MODEL WAS THE SAME AS THAT OF THE LABORATORY FOR OVER 86 PERCENT OF THE ISOLATES. (LITTLE-BATTELLE) JF - APPLIED MICROBIOLOGY, VOL 26, NO 3, P 314-317, SEPTEMBER 1973. 3 TAB, 10 REF. AU - Friedman, R AU - MacLowry, J AD - NATIONAL INSTITUTES OF HEALTH, BETHESDA, MD. CLINICAL PATHOLOGY DEPT Y1 - 1973/09// PY - 1973 DA - Sep 1973 KW - Water Resources Abstracts KW - *COMPUTER PROGRAMS KW - *POLLUTANT IDENTIFICATION KW - *PATHOGENIC BACTERIA KW - *ENTERIC BACTERIA KW - *ANTIBIOTICS(PESTICIDES) KW - *MATHEMATICAL MODELS KW - PSEUDOMONAS KW - SALMONELLA KW - STREPTOCOCCUS KW - E. COLI KW - SENSITIVITY KW - ACCURACY KW - SELECTIVE MEDIA KW - STAPHYLOCOCCUS KW - KLEBSIELLA KW - PROTEUS KW - SERRATIA KW - ENTEROBACTER KW - CITROBACTER KW - BACTEROIDES KW - HAEMOPHILUS KW - HERELLEA KW - BACILLUS KW - PROVIDENCE KW - SW 5080:Evaluation, processing and publication KW - SW 3010:Identification of pollutants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19070892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=COMPUTER+IDENTIFICATION+OF+BACTERIA+ON+THE+BASIS+OF+THEIR+ANTIBIOTIC+SUSCEPTIBILITY+PATTERNS&rft.au=Friedman%2C+R%3BMacLowry%2C+J&rft.aulast=Friedman&rft.aufirst=R&rft.date=1973-09-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - The Registry, Some Reminiscences and the Future AN - 877596834; 13645400 JF - Toxicologic Pathology AU - Stewart, Harold L AD - Registry of Experimental Cancers, National Cancer Institute. Bethesda, Maryland 20014 Y1 - 1973/06// PY - 1973 DA - Jun 1973 SP - 3 EP - 5 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 1 IS - 3 SN - 0192-6233, 0192-6233 KW - Toxicology Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877596834?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+Pathology&rft.atitle=The+Registry%2C+Some+Reminiscences+and+the+Future&rft.au=Stewart%2C+Harold+L&rft.aulast=Stewart&rft.aufirst=Harold&rft.date=1973-06-01&rft.volume=1&rft.issue=3&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Toxicologic+Pathology&rft.issn=01926233&rft_id=info:doi/10.1177%2F019262337300100303 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2012-06-18 DO - http://dx.doi.org/10.1177/019262337300100303 ER - TY - JOUR T1 - Effect of anoxia on the cations and direct current potential in the endolymph. An experiment on the kanamycin sulfate-poisoned guinea pig. AN - 85254476; pmid-4704440 JF - Archives of Otolaryngology (Chicago, Ill. : 1960) AU - Nakashima, T AU - Leonard, J E AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1973 SP - 452 EP - 456 VL - 97 IS - 6 SN - 0003-9977, 0003-9977 KW - Sodium KW - Guinea Pigs KW - Methods KW - Animal KW - Potassium KW - Kanamycin KW - Electrophysiology KW - Organ of Corti KW - Asphyxia KW - Anoxia KW - Labyrinthine Fluids UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85254476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.atitle=Effect+of+anoxia+on+the+cations+and+direct+current+potential+in+the+endolymph.+An+experiment+on+the+kanamycin+sulfate-poisoned+guinea+pig.&rft.au=Nakashima%2C+T%3BLeonard%2C+J+E%3BSnow%2C+J+B&rft.aulast=Nakashima&rft.aufirst=T&rft.date=1973-06-01&rft.volume=97&rft.issue=6&rft.spage=452&rft.isbn=&rft.btitle=&rft.title=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.issn=00039977&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Clinical manifestations other than audiologic findings of retrocochlear lesions. AN - 85205880; pmid-4541190 JF - Advances in Oto-Rhino-Laryngology AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1973 SP - 258 EP - 270 VL - 20 SN - 0065-3071, 0065-3071 KW - Facial Nerve KW - Cerebellopontine Angle KW - Diagnosis, Differential KW - Human KW - Tomography, X-Ray KW - Meningioma KW - Trigeminal Nerve KW - Vestibular Function Tests KW - Cerebellar Neoplasms KW - Vestibulocochlear Nerve KW - Neurilemmoma KW - Peripheral Nervous System Neoplasms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85205880?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Oto-Rhino-Laryngology&rft.atitle=Clinical+manifestations+other+than+audiologic+findings+of+retrocochlear+lesions.&rft.au=Snow%2C+J+B&rft.aulast=Snow&rft.aufirst=J&rft.date=1973-01-01&rft.volume=20&rft.issue=&rft.spage=258&rft.isbn=&rft.btitle=&rft.title=Advances+in+Oto-Rhino-Laryngology&rft.issn=00653071&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Pseudomonas meningitis complicating radical resection for radiorecurrent cancer of the paranasal sinuses: Report of two patients successfully treated with intrathecal polymyxin AN - 754560605; 13378368 AB - Pseudomonas meningitis is a grave complication of craniofacial surgery and radiotherapy. The management of this complication is reviewed and illustrated by the course of two patients who were successfully treated after radical resection for radiorecurrent cancer of the paranasal sinuses was complicated by pseudomonas meningitis. JF - Journal of Surgical Oncology AU - Geelhoed, Glenn W AU - Ketcham, Alfred S AD - Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Md. 20014 PY - 1973 SP - 365 EP - 374 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 5 IS - 4 SN - 0022-4790, 0022-4790 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; CSA Neurosciences Abstracts KW - Polymyxins KW - Surgery KW - Radiotherapy KW - Pseudomonas KW - Sinus KW - Cancer KW - Meningitis KW - Radicals KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - N3 11027:Neurology & neuropathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754560605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Surgical+Oncology&rft.atitle=Pseudomonas+meningitis+complicating+radical+resection+for+radiorecurrent+cancer+of+the+paranasal+sinuses%3A+Report+of+two+patients+successfully+treated+with+intrathecal+polymyxin&rft.au=Geelhoed%2C+Glenn+W%3BKetcham%2C+Alfred+S&rft.aulast=Geelhoed&rft.aufirst=Glenn&rft.date=1973-01-01&rft.volume=5&rft.issue=4&rft.spage=365&rft.isbn=&rft.btitle=&rft.title=Journal+of+Surgical+Oncology&rft.issn=00224790&rft_id=info:doi/10.1002%2Fjso.2930050412 L2 - http://www3.interscience.wiley.com/journal/112720859/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2015-12-09 N1 - SubjectsTermNotLitGenreText - Polymyxins; Surgery; Radiotherapy; Sinus; Cancer; Radicals; Meningitis; Pseudomonas DO - http://dx.doi.org/10.1002/jso.2930050412 ER - TY - JOUR T1 - Enzymatic cleavage of methotrexate provides a method for prevention of drug toxicity. AN - 81316236; 12635300 JF - Nature AU - Chabner, B A AU - Johns, D G AU - Bertino, J R AD - Laboratory of Chemical Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014, USA. Y1 - 1972/10/13/ PY - 1972 DA - 1972 Oct 13 SP - 395 EP - 397 VL - 239 IS - 5372 SN - 0028-0836, 0028-0836 KW - Antineoplastic Agents KW - 0 KW - gamma-Glutamyl Hydrolase KW - EC 3.4.19.9 KW - Leucovorin KW - Q573I9DVLP KW - Methotrexate KW - YL5FZ2Y5U1 KW - Index Medicus KW - Leukemia -- drug therapy KW - Animals KW - Survival Rate KW - Half-Life KW - Weight Loss -- drug effects KW - Mice KW - Time Factors KW - Hydrolysis KW - Male KW - Leucovorin -- therapeutic use KW - Leucovorin -- pharmacokinetics KW - gamma-Glutamyl Hydrolase -- administration & dosage KW - Antineoplastic Agents -- pharmacokinetics KW - Antineoplastic Agents -- metabolism KW - Antineoplastic Agents -- adverse effects KW - gamma-Glutamyl Hydrolase -- metabolism KW - Pseudomonas -- enzymology KW - Methotrexate -- pharmacokinetics KW - gamma-Glutamyl Hydrolase -- pharmacokinetics KW - Methotrexate -- adverse effects KW - Methotrexate -- therapeutic use KW - Drug-Related Side Effects and Adverse Reactions -- drug therapy KW - gamma-Glutamyl Hydrolase -- therapeutic use KW - Drug-Related Side Effects and Adverse Reactions -- prevention & control KW - Methotrexate -- metabolism KW - Antineoplastic Agents -- therapeutic use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/81316236?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Enzymatic+cleavage+of+methotrexate+provides+a+method+for+prevention+of+drug+toxicity.&rft.au=Chabner%2C+B+A%3BJohns%2C+D+G%3BBertino%2C+J+R&rft.aulast=Chabner&rft.aufirst=B&rft.date=1972-10-13&rft.volume=239&rft.issue=5372&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=Nature&rft.issn=00280836&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-04-09 N1 - Date created - 2003-03-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Mental Health in the Classroom AN - 1290862000 JF - Today's Education AU - Brown, Bertram S AU - Ellis Long, Barbara AU - Morse, William C Y1 - 1972/09/01/ PY - 1972 DA - 1972 Sep 01 SP - 48 CY - Washington PB - National Education Association of the United States. VL - 61 IS - 6 SN - 0040-8484 KW - Education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1290862000?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apio&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Today%27s+Education&rft.atitle=Mental+Health+in+the+Classroom&rft.au=Brown%2C+Bertram+S%3BEllis+Long%2C+Barbara%3BMorse%2C+William+C&rft.aulast=Brown&rft.aufirst=Bertram&rft.date=1972-09-01&rft.volume=61&rft.issue=6&rft.spage=48&rft.isbn=&rft.btitle=&rft.title=Today%27s+Education&rft.issn=00408484&rft_id=info:doi/ DB - Periodicals Index Online N1 - Last updated - 2013-02-21 ER - TY - JOUR T1 - Adrenalinogenic secretion of nonchromaffin paraganglioma. AN - 85193230; pmid-4338567 JF - The Laryngoscope AU - Seda, H J AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1972 SP - 973 EP - 977 VL - 82 IS - 6 SN - 0023-852X, 0023-852X KW - Catecholamines KW - Carotid Body Tumor KW - Human KW - Paraganglioma, Extra-Adrenal KW - Adult KW - Epinephrine KW - Female KW - Hypertension UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85193230?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Adrenalinogenic+secretion+of+nonchromaffin+paraganglioma.&rft.au=Seda%2C+H+J%3BSnow%2C+J+B&rft.aulast=Seda&rft.aufirst=H&rft.date=1972-06-01&rft.volume=82&rft.issue=6&rft.spage=973&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Clinical trials with 5-[3,3-bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide (NSC-82196) given intravenously. AN - 81860786; 19051499 AB - Clinical trials with 5-[3,3-bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide (NSC-82196) given intravenously to 32 patients with various tumors suggest that the maximum tolerated dose is 5 g/m2 divided into five consecutive daily injections and repeated at 5-6-week intervals. The principal dose-limiting toxic effect was severe nausea and vomiting. Pain and flushing after administration were often severe. The time of onset and the degree of severity of delayed bone marrow toxicity (nadir, 31-35 days) were erratic, but the toxicity was reversible and usually tolerable. One patient with lymphosarcoma had an objective response. Phase II trials with NSC-82196 in patients with lymphoma and melanoma appear warranted. JF - Cancer chemotherapy reports AU - Bagley, C M AU - Canellos, G P AU - Young, R C AU - Gallelli, J F AU - Devita, V T AD - Solid Tumor Service, NCI, Bethesda, MD, USA. Y1 - 1972/06// PY - 1972 DA - June 1972 SP - 387 EP - 391 VL - 56 IS - 3 SN - 0069-0112, 0069-0112 KW - Antineoplastic Agents KW - 0 KW - Nitrogen Mustard Compounds KW - imidazole mustard KW - 5034-77-5 KW - Index Medicus KW - Lymphoma, Non-Hodgkin -- drug therapy KW - Infusions, Intravenous KW - Dose-Response Relationship, Drug KW - Humans KW - Blood Platelets -- drug effects KW - Treatment Outcome KW - Time Factors KW - Bone Marrow -- drug effects KW - Male KW - Female KW - Leukocytes -- drug effects KW - Nitrogen Mustard Compounds -- administration & dosage KW - Antineoplastic Agents -- administration & dosage KW - Antineoplastic Agents -- toxicity KW - Nitrogen Mustard Compounds -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/81860786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+chemotherapy+reports&rft.atitle=Clinical+trials+with+5-%5B3%2C3-bis%282-chloroethyl%29-1-triazeno%5Dimidazole-4-carboxamide+%28NSC-82196%29+given+intravenously.&rft.au=Bagley%2C+C+M%3BCanellos%2C+G+P%3BYoung%2C+R+C%3BGallelli%2C+J+F%3BDevita%2C+V+T&rft.aulast=Bagley&rft.aufirst=C&rft.date=1972-06-01&rft.volume=56&rft.issue=3&rft.spage=387&rft.isbn=&rft.btitle=&rft.title=Cancer+chemotherapy+reports&rft.issn=00690112&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-04-24 N1 - Date created - 2008-12-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Clinical, radiologic, and histopathologic studies on pulmonary toxicity induced by treatment with bleomycin (NSC-125066). AN - 81858938; 19051494 AB - This study describes the clinical, roentgenologic, and histopathologic studies of pulmonary toxicity induced by treatment with bleomycin. In 168 patients with evaluable cases who were treated with different dose schedules of bleomycin, the overall incidence of pulmonary toxicity was 39.8%. The mean total dose producing pulmonary damage was about 100-150 mg/m2. In 31 patients (46%), pulmonary changes were detected only after systematic auscultation of the lungs (fine crepitant rales at one or both bases). In 36 patients (54%), roentgenograms showed reticular or reticular micronodular lesions located mostly at the lower lung zones and at the costophrenic angle 1-2 weeks after the crepitations were noted. In seven patients postmortem examination revealed hyperplasia and endoalveolar migration of type II pneumocytes and macrophages, fibrinous edema, hyaline membranes, and newly formed reticular and collagen fibers within the alveolar septa. The radiologic and histopathologic findings were consistent with the diagnosis of interstitial pneumonia. These pulmonary reactions represent a delayed dose-dependent bleomycin effect and are probably due to the preferential distribution of the drug in the lung tissue. JF - Cancer chemotherapy reports AU - De Lena, M AU - Guzzon, A AU - Monfardini, S AU - Bonadonna, G AD - National Cancer Institute, Milan, Italy. Y1 - 1972/06// PY - 1972 DA - June 1972 SP - 343 EP - 356 VL - 56 IS - 3 SN - 0069-0112, 0069-0112 KW - Antibiotics, Antineoplastic KW - 0 KW - Bleomycin KW - 11056-06-7 KW - Index Medicus KW - Hyperplasia KW - Aged, 80 and over KW - Humans KW - Adult KW - Aged KW - Middle Aged KW - Child KW - Adolescent KW - Male KW - Female KW - Pulmonary Fibrosis -- metabolism KW - Macrophages -- metabolism KW - Bleomycin -- pharmacology KW - Antibiotics, Antineoplastic -- pharmacology KW - Lung -- drug effects KW - Antibiotics, Antineoplastic -- adverse effects KW - Bleomycin -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/81858938?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+chemotherapy+reports&rft.atitle=Clinical%2C+radiologic%2C+and+histopathologic+studies+on+pulmonary+toxicity+induced+by+treatment+with+bleomycin+%28NSC-125066%29.&rft.au=De+Lena%2C+M%3BGuzzon%2C+A%3BMonfardini%2C+S%3BBonadonna%2C+G&rft.aulast=De+Lena&rft.aufirst=M&rft.date=1972-06-01&rft.volume=56&rft.issue=3&rft.spage=343&rft.isbn=&rft.btitle=&rft.title=Cancer+chemotherapy+reports&rft.issn=00690112&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-04-24 N1 - Date created - 2008-12-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Perceptual dynamics of drug addicts as measured by the semantic differential test AN - 85472358; 7301484 AB - The perception of other persons, concepts, and drugs was measured in 54 male drug addicts by means of a 17 item Semantic Differential Test incorporating the three main factors: evaluation, potency, activity. Major findings were: (1) Subjects denied the reality of their situation by showing stronger identification with "straight" persons than with addicts; (2) The major effect of taking "your favorite drug" (in most, but not all cases heroin) was to make the self more relaxed and calm, and other persons and the world in general less threatening; (3) Marihuana is extremely highly regarded apparently because it produces all the desired effects, but none of the drawbacks of other drugs; and (4) Subjects can indeed perceive the criminality of an act, but not to the extent other groups do. JF - Perceptual and Motor Skills AU - Rudin, Stanley A AD - Personality & Clinical Unit, NIMH Clinical Research Center, Leestown Pike, Lexington, Ky. 40507 Y1 - 1972///0, PY - 1972 DA - 0, 1972 SP - 451 EP - 460 VL - 35 IS - 2 SN - 0031-5125, 0031-5125 KW - perceptual dynamics of drug addicts KW - semantic differential test KW - Drug Effects (dr2) KW - Personality and Personality Investigation (pe7) KW - Semantic Differential (se7) KW - Interpersonal Behavior (in15) KW - Self Perception (se6) KW - article KW - 6410: language-pathological and normal; language-pathological and normal UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85472358?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Allba&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Perceptual+and+Motor+Skills&rft.atitle=Perceptual+dynamics+of+drug+addicts+as+measured+by+the+semantic+differential+test&rft.au=Rudin%2C+Stanley+A&rft.aulast=Rudin&rft.aufirst=Stanley&rft.date=1972-01-01&rft.volume=35&rft.issue=2&rft.spage=451&rft.isbn=&rft.btitle=&rft.title=Perceptual+and+Motor+Skills&rft.issn=00315125&rft_id=info:doi/ LA - English DB - Linguistics and Language Behavior Abstracts (LLBA) N1 - Date revised - 2003-10-01 N1 - Last updated - 2016-09-27 N1 - CODEN - PMOSAZ N1 - SubjectsTermNotLitGenreText - Drug Effects (dr2); Self Perception (se6); Interpersonal Behavior (in15); Personality and Personality Investigation (pe7); Semantic Differential (se7) ER - TY - JOUR T1 - Pupil responses of addicts in treatment to drug culture argot: I. Auditory presentation of double entendre words AN - 57876848; 7300062 AB - Eleven addicts in treatment and eight nonaddicts familiar with addict argot were asked to listen to and think about a series of words, half of which were double entendre, having one of their meanings in the addict argot. Pupil size, the dependent variable, was recorded continuously via infrared cinematography. Both groups of Ss responded differentially to the two kinds of words. These results were interpreted in terms of the cognitive processing of the stimuli rather than their emotional impact. JF - Psychonomic Science AU - Altman, Fred AU - Bernick, Niles AU - Mintz, Daniel L AD - NIMH Clinical Research Center, Lexington, Ky. 40507 Y1 - 1972///0, PY - 1972 DA - 0, 1972 SP - 79 EP - 80 VL - 28 IS - 2 SN - 0033-3131, 0033-3131 KW - pupil response to drug culture argot KW - double entendre words KW - addicts vs. normals KW - Auditory Stimulation (au7) KW - Eye Movement (ey1) KW - Word and Letter Association (wo2) KW - Register (re8) KW - article KW - 4010: psycholinguistics; psycholinguistics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57876848?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Allba&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychonomic+Science&rft.atitle=Pupil+responses+of+addicts+in+treatment+to+drug+culture+argot%3A+I.+Auditory+presentation+of+double+entendre+words&rft.au=Altman%2C+Fred%3BBernick%2C+Niles%3BMintz%2C+Daniel+L&rft.aulast=Altman&rft.aufirst=Fred&rft.date=1972-01-01&rft.volume=28&rft.issue=2&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Psychonomic+Science&rft.issn=00333131&rft_id=info:doi/ LA - English DB - Linguistics and Language Behavior Abstracts (LLBA) N1 - Date revised - 2003-10-01 N1 - Last updated - 2016-09-27 N1 - CODEN - PSYSBQ N1 - SubjectsTermNotLitGenreText - Word and Letter Association (wo2); Eye Movement (ey1); Register (re8); Auditory Stimulation (au7) ER - TY - JOUR T1 - Pupil responses of addicts in treatment to drug culture argot: II. Responses during verbalization of visually presented words AN - 57869484; 7300063 AB - Part II of an investigation of pupil responses of addicts to drug culture argot. (See previous abstract.). A series of words falling into the categories of control, sex, and drug argot were visually presented to 10 addicts in treatment. The latter two categories were composed of double entendre words, one of the meanings of which referred to sex or drug argot. Subjects were asked to verbalize each word as it was presented. Mean pupil responses did not differentiate the stimulus categories; however, psychometric scales relating to addiction and sexual orientation correlated significantly with pupil responses to the appropriate stimulus categories. JF - Psychonomic Science AU - Bernick, Niles AU - Altman, Fred AU - Mintz, Daniel L AD - NIMH Clinical Research Center, Lexington, Ky. 40507 Y1 - 1972///0, PY - 1972 DA - 0, 1972 SP - 81 EP - 82 VL - 28 IS - 2 SN - 0033-3131, 0033-3131 KW - pupil response to drug culture argot KW - sex vs. drug argot vs. control words KW - addicts KW - Eye Movement (ey1) KW - Word and Letter Association (wo2) KW - Visual Stimulation (vi2) KW - Register (re8) KW - article KW - 4010: psycholinguistics; psycholinguistics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57869484?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Allba&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychonomic+Science&rft.atitle=Pupil+responses+of+addicts+in+treatment+to+drug+culture+argot%3A+II.+Responses+during+verbalization+of+visually+presented+words&rft.au=Bernick%2C+Niles%3BAltman%2C+Fred%3BMintz%2C+Daniel+L&rft.aulast=Bernick&rft.aufirst=Niles&rft.date=1972-01-01&rft.volume=28&rft.issue=2&rft.spage=81&rft.isbn=&rft.btitle=&rft.title=Psychonomic+Science&rft.issn=00333131&rft_id=info:doi/ LA - English DB - Linguistics and Language Behavior Abstracts (LLBA) N1 - Date revised - 2003-10-01 N1 - Last updated - 2016-09-27 N1 - CODEN - PSYSBQ N1 - SubjectsTermNotLitGenreText - Visual Stimulation (vi2); Eye Movement (ey1); Register (re8); Word and Letter Association (wo2) ER - TY - JOUR T1 - CHROMATOGRAPHIC AND BIOLOGICAL ASPECTS OF POLYCHLORINATED BIPHENYLS AN - 19056262; 7214804 AB - INFORMATION RELATIVE TO THE BIOLOGICAL DECOMPOSITION OF POLYCHLORINATED BIPHENYLS IS SCANT. THEY ARE MORE STABLE THAN DDT AND ITS METABOLITES SINCE THE PCBS LACK THE ETHANE COMPONENT BETWEEN THE AROMATIC RINGS. THIS FACTOR COUPLED WITH THEIR PHYSICAL AND CHEMICAL CHARACTERISTICS FOR PERSISTENCE INDICATES THAT THESE MATERIALS ARE CAPABLE OF BIOLOGICAL MAGNIFICATION UP THE FOOD CHAIN. THEIR HIGH LIPID SOLUBILITY RESULTS IN ACCUMULATION IN FATTY TISSUES OF LOWER ANIMALS AND MARINE LIFE. BECAUSE OF VERY LOW AQUEOUS SOLUBILITY, THEY ACCUMULATE ON UNDERWATER SEDIMENTS IN RELATIVELY HIGH CONCENTRATION AND REDISSOLVE VERY SLOWLY. IN DESCRIBING EFFECTS AND INTERACTIONS OF ENVIRONMENTAL CHEMICALS (ASPIRIN, CAFFEINE, AROCLOR 1254, CARBARYL, PARATHION, DDT, AND SEVERAL INSECTICIDE METABOLITES) ON HUMAN CELLS IN TISSUE CULTURE, ASPIRIN AND CAFFEINE WERE 8 TO 20 TIMES LESS TOXIC THAN THE OTHER AGENTS STUDIED WHILE THE PCB PLASTICIZER AROCLOR 1254 WAS AS TOXIC AS DDT. THE CHROMATOGRAPHIC (COLUMN, THIN-LAYER AND GAS-LIQUID AND COMBINED GAS-LIQUID CHROMATOGRAPHY AND MASS SPECTROS COPY) AND BIOLOGICAL ASPECTS OF THE POLYCHLORINATED BIPHENYLS ARE REVIEWED WITH PRIMARY FOCUS AS TO THEIR UTILITY, ECOLOGICAL DISTRIBUTION AND TOXICITY AS WELL AS DIVERSE TECHNIQUES FOR THEIR SEPARATION FROM CHLORINATED PESTICIDES AND SUBSEQUENT ANALYSIS. (JONES-WISCONSIN) JF - JOURNAL OF CHROMATOGRAPHY, VOL 68, P 345-426, 1972. 8 FIG, 37 TAB, 113 REF. AU - Fishbein, L AD - NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES, RESEARCH TRIANGLE PARK, N.C Y1 - 1972 PY - 1972 DA - 1972 KW - Water Resources Abstracts KW - *POLYCHLORINATED BIPHENYLS KW - *CHROMATOGRAPHY KW - *ANALYTICAL TECHNIQUES KW - ECOLOGICAL DISTRIBUTION KW - TOXICITY KW - PESTICIDES KW - CHLORINATED HYDROCARBON PESTICIDES KW - MASS SPECTROMETRY KW - POLLUTANT IDENTIFICATION KW - AROCLORS KW - LETHAL LIMIT KW - PATHOLOGY KW - PESTICIDE RESIDUES KW - DDT KW - DDD KW - DDE KW - *PESTICIDE ANALYSIS KW - CHLORINATED NAPTHALINES KW - ORGANOCHLORINE PESTICIDES KW - DIBENZOFURANS KW - SW 3010:Identification of pollutants KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19056262?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=CHROMATOGRAPHIC+AND+BIOLOGICAL+ASPECTS+OF+POLYCHLORINATED+BIPHENYLS&rft.au=Fishbein%2C+L&rft.aulast=Fishbein&rft.aufirst=L&rft.date=1972-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Pathophysiologic responses of the inner ear to intense sound. AN - 85169124; pmid-5127757 JF - The Annals of Otology, Rhinology, and Laryngology AU - Snow, J B AU - Suga, F AU - Sullivan, M J AU - Nakashima, T AU - Leonard, J E AU - Meiring, N L AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA.; Kresge Hearing Research Institute, University of Michigan Medical School, Ann Arbor. PY - 1971 SP - 871 EP - 880 VL - 80 IS - 6 SN - 0003-4894, 0003-4894 KW - Cochlea KW - Sodium KW - Animals KW - Deafness KW - Hearing Loss, Noise-Induced KW - Guinea Pigs KW - Biological Transport KW - Noise KW - Potassium KW - Ear, Inner KW - Labyrinthine Fluids KW - Microelectrodes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85169124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Pathophysiologic+responses+of+the+inner+ear+to+intense+sound.&rft.au=Snow%2C+J+B%3BSuga%2C+F%3BSullivan%2C+M+J%3BNakashima%2C+T%3BLeonard%2C+J+E%3BMeiring%2C+N+L&rft.aulast=Snow&rft.aufirst=J&rft.date=1971-12-01&rft.volume=80&rft.issue=6&rft.spage=871&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Cations in the endolymph with noise-induced deafness. AN - 85252196; pmid-5556267 JF - Archives of Otolaryngology (Chicago, Ill. : 1960) AU - Nakashima, T AU - Meiring, N L AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1971 SP - 109 EP - 113 VL - 94 IS - 2 SN - 0003-9977, 0003-9977 KW - Sodium KW - Ions KW - Deafness KW - Hearing Loss, Noise-Induced KW - Guinea Pigs KW - Electrodes KW - Animal KW - Biological Transport KW - Potassium KW - Organ of Corti KW - Labyrinthine Fluids UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85252196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.atitle=Cations+in+the+endolymph+with+noise-induced+deafness.&rft.au=Nakashima%2C+T%3BMeiring%2C+N+L%3BSnow%2C+J+B&rft.aulast=Nakashima&rft.aufirst=T&rft.date=1971-08-01&rft.volume=94&rft.issue=2&rft.spage=109&rft.isbn=&rft.btitle=&rft.title=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.issn=00039977&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Ultrasonic irradiation on the inner ear. AN - 85176731; pmid-5313765 JF - The Laryngoscope AU - Seda, H J AU - Suga, F AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1971 SP - 510 EP - 523 VL - 81 IS - 4 SN - 0023-852X, 0023-852X KW - Cochlea KW - Auditory Threshold KW - Cats KW - Animal KW - Action Potentials KW - Cochlear Nerve KW - Vestibule KW - Organ of Corti KW - Labyrinth Diseases KW - Ultrasonics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85176731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Ultrasonic+irradiation+on+the+inner+ear.&rft.au=Seda%2C+H+J%3BSuga%2C+F%3BSnow%2C+J+B&rft.aulast=Seda&rft.aufirst=H&rft.date=1971-04-01&rft.volume=81&rft.issue=4&rft.spage=510&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - IMMEDIATE PRECURSORS TO HEROIN ADDICTION AN - 60918974; 72F6693 AB - A review of studies of heroin use shows a general concern with the various pathways of illegal drug use. But most of them have not dealt with diff's in use of drugs according to SE variables nor about the procursors to heroin addiction. Data for 1,096 addict-patients admitted during Jul 21, 1967-May 20, 1969 to the Nat'l Instit for Mental Health Clinical Res Center were collected via the Soc Data Form. Of these, 738 were hooked on heroin at some time. For 292 heroin was the first drug on which they were hooked. 446 reported becoming hooked on heroin after being hooked on some other drug. Some similarities & diff's between these 2 groups are pointed out. 35.5% reported marijuana as the immdeiate precursor for heroin addiction, 17.9% alcohol, & 17.9% other narcotics, 8.2% cough syrup, & the remainder various other drugs from sedative hypnotic relaxants to organic solvents. Subsample variations are analyzed. Although marijuana & alcohol are the most important single precursor drugs, a variety of other immediate precursors were used by 46.6% of the total sample. Data confirm the hypothesis that immediate precursors vary signif'ly when soc context is taken into account. Alcohol accounted for more blacks than whites & more older than younger addicts; it was more frequent as an immediate precursor for F's than marijuana. R's from the higher SES abused many more diff drugs than R's from the lower SES. The evidence shows that generalizations about drugs, whether marijuana or others, immediately preceding heroin, need to be examined re their soc context. The role played by a particular drug as precursor can vary from one soc group to another. The nonchemical factors that may lead to heroin addiction must also be studied (eg, becoming 'hooked' as a way of life). 5 Tables. M. Maxfield. JF - Journal of Health and Social Behavior AU - Weppner, Robert S AU - Agar, Michael H AD - NIMH CLINICAL RES CENTER, LEXINGTON, KY Y1 - 1971/03// PY - 1971 DA - March 1971 SP - 10 EP - 17 VL - 12 IS - 1 SN - 0022-1465, 0022-1465 KW - DRUG : PRECURSORS, & HEROIN ADDICTION KW - Status/Statuses KW - Drug/Drugs KW - Heroin KW - Socioeconomic (see also Socioeconomic status) KW - article KW - 2045: sociology of health and medicine; sociology of medicine (public health) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60918974?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Health+and+Social+Behavior&rft.atitle=IMMEDIATE+PRECURSORS+TO+HEROIN+ADDICTION&rft.au=Weppner%2C+Robert+S%3BAgar%2C+Michael+H&rft.aulast=Weppner&rft.aufirst=Robert&rft.date=1971-03-01&rft.volume=12&rft.issue=1&rft.spage=10&rft.isbn=&rft.btitle=&rft.title=Journal+of+Health+and+Social+Behavior&rft.issn=00221465&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JHSBA5 N1 - SubjectsTermNotLitGenreText - Drug/Drugs; Heroin; Socioeconomic (see also Socioeconomic status); Status/Statuses ER - TY - JOUR T1 - Experimental microembolization of cochlear vessels. AN - 85251664; pmid-5502422 JF - Archives of Otolaryngology (Chicago, Ill. : 1960) AU - Suga, F AU - Preston, J AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1970 SP - 213 EP - 220 VL - 92 IS - 3 SN - 0003-9977, 0003-9977 KW - Cochlea KW - Blood Flow Velocity KW - Evoked Potentials KW - Embolism KW - Guinea Pigs KW - Vestibulocochlear Nerve KW - Animal KW - Action Potentials KW - Phenoxybenzamine KW - Temporal Bone KW - Regional Blood Flow KW - Isoproterenol KW - Carbon Dioxide KW - Barium Sulfate UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85251664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.atitle=Experimental+microembolization+of+cochlear+vessels.&rft.au=Suga%2C+F%3BPreston%2C+J%3BSnow%2C+J+B&rft.aulast=Suga&rft.aufirst=F&rft.date=1970-09-01&rft.volume=92&rft.issue=3&rft.spage=213&rft.isbn=&rft.btitle=&rft.title=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.issn=00039977&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Carbon black inhalation into the larynx and trachea. AN - 85178511; pmid-5416460 JF - The Laryngoscope AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1970 SP - 267 EP - 287 VL - 80 IS - 2 SN - 0023-852X, 0023-852X KW - Air Pollution KW - Chemistry, Physical KW - Respiration KW - Animal KW - Edema KW - Hamsters KW - Models, Biological KW - Dust KW - Absorption KW - Larynx KW - Epithelium KW - Laryngeal Diseases KW - Trachea KW - Carbon UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85178511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Carbon+black+inhalation+into+the+larynx+and+trachea.&rft.au=Snow%2C+J+B&rft.aulast=Snow&rft.aufirst=J&rft.date=1970-02-01&rft.volume=80&rft.issue=2&rft.spage=267&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Some structural and biological properties of Brucella endotoxin. AN - 733479161; 16557710 AB - Hot phenol-water extraction of smooth Brucella abortus and B. melitensis cells yielded a toxic fraction which was recovered from the phenol phase (fraction 5). Chemically, fractions 5 from both Brucella species were lipid-carbohydrate-protein-2 keto-3-deoxyoctulosonic acid complexes which were stable to heat and resistant to Pronase digestion. Electron micrographs of the Brucella toxins were morphologically indistinguishable from those of enterobacterial endotoxins. Biologically, Brucella toxins were lethal for mice and immunogenic for rabbits. An intravenous injection of Brucella toxin induced severe leukopenia with subsequent leukocytosis in mice. Cross-tolerance experiments with mice demonstrated that pretreatment with B. abortus toxin lessened the hypoferremia produced by challenge with Escherichia coli endotoxin. Furthermore, fractions 5 from B. abortus and B. melitensis were able to form hybrids with E. coli and Salmonella enteritidis endotoxins and also with each other. Although Brucella toxins possess many structural and biological properties in common with endotoxins from the Enterobacteriaceae, some quantitative differences in their biological potencies were observed. Brucella toxins were relatively innocuous in tests for pyrogenicity in rabbits and lethality for chick embryos. In nonspecific protection tests, Brucella toxin had only 1/75 the potency of E. coli endotoxin in protecting mice against challenge with virulent S. typhi. However, on the basis of the data presented and on the work done previously, we concluded that the heat-stable toxins of B. abortus and B. melitensis were endotoxins. JF - Infection and immunity AU - Leong, D AU - Diaz, R AU - Milner, K AU - Rudbach, J AU - Wilson, J B AD - Rocky Mountain Laboratory, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840. Y1 - 1970/02// PY - 1970 DA - February 1970 SP - 174 EP - 182 VL - 1 IS - 2 SN - 0019-9567, 0019-9567 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733479161?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+and+immunity&rft.atitle=Some+structural+and+biological+properties+of+Brucella+endotoxin.&rft.au=Leong%2C+D%3BDiaz%2C+R%3BMilner%2C+K%3BRudbach%2C+J%3BWilson%2C+J+B&rft.aulast=Leong&rft.aufirst=D&rft.date=1970-02-01&rft.volume=1&rft.issue=2&rft.spage=174&rft.isbn=&rft.btitle=&rft.title=Infection+and+immunity&rft.issn=00199567&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-06-29 N1 - Date created - 2010-06-29 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Bacteriol. 1964 Feb;87:391-400 [14151062] J Exp Med. 1961 Nov 1;114:647-63 [14491836] Proc Soc Exp Biol Med. 1962 May;110:191-3 [14453507] J Exp Med. 1961 Nov 1;114:665-84 [13905235] J Biol Chem. 1959 Apr;234(4):705-9 [13654246] J Immunol. 1959 Jan;82(1):75-84 [13620919] Bull World Health Organ. 1958;19(1):177-86 [13585067] J Bacteriol. 1968 Oct;96(4):893-901 [4176644] J Bacteriol. 1966 Nov;92(5):1493-509 [4288609] J Bacteriol. 1965 Oct;90(4):903-10 [4954519] J Bacteriol. 1965 Oct;90(4):895-902 [4954518] J Exp Med. 1967 Jul 1;126(1):63-79 [4961269] J Bacteriol. 1969 Jan;97(1):32-41 [4974396] J Bacteriol. 1968 Feb;95(2):612-7 [4966552] J Bacteriol. 1968 Feb;95(2):625-30 [5689122] J Bacteriol. 1968 Jun;95(6):2035-43 [5669888] J Biol Chem. 1967 Oct 25;242(20):4610-3 [6061407] J Bacteriol. 1967 Apr;93(4):1262-8 [6032505] J Bacteriol. 1967 May;93(5):1681-7 [6025452] Biochim Biophys Acta. 1966 Sep 26;127(1):271-3 [5970884] J Infect Dis. 1966 Dec;116(5):529-36 [5957260] J Biol Chem. 1966 Mar 25;241(6):1424-8 [5935353] J Biol Chem. 1965 Dec;240(12):4549-55 [5846977] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Sodium and potassium ions in endolymph. In vivo measurements with glass microelectrodes. AN - 85261888; pmid-5409717 JF - Archives of Otolaryngology (Chicago, Ill. : 1960) AU - Suga, F AU - Nakashima, T AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1970 SP - 37 EP - 43 VL - 91 IS - 1 SN - 0003-9977, 0003-9977 KW - Cochlea KW - Sodium KW - Guinea Pigs KW - Electrodes KW - Animal KW - Sound KW - Potassium KW - Asphyxia KW - Labyrinthine Fluids UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85261888?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.atitle=Sodium+and+potassium+ions+in+endolymph.+In+vivo+measurements+with+glass+microelectrodes.&rft.au=Suga%2C+F%3BNakashima%2C+T%3BSnow%2C+J+B&rft.aulast=Suga&rft.aufirst=F&rft.date=1970-01-01&rft.volume=91&rft.issue=1&rft.spage=37&rft.isbn=&rft.btitle=&rft.title=Archives+of+Otolaryngology+%28Chicago%2C+Ill.+%3A+1960%29&rft.issn=00039977&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - BIOLOGICAL ASPECTS OF THE SALINE WATER PROBLEM AN - 18977615; 7007376 AB - RESEARCH ON LIVING ORGANISMS YIELDED A BACKGROUND OF POTENTIALLY USEFUL INFORMATION ON DESALINATION MEMBRANES. NATURE HAS PROVIDED HIGHLY EFFICIENT MECHANISMS, IN LIVING ORGANISMS, FOR THE PERFORMANCE OF THE EXACT FUNCTION DESIRED IN DESALINATION-THE EXTRACTION OF IONS FROM WATER AGAINST TREMENDOUS CHEMICAL POTENTIAL GRADIENTS. SUCH UPHILL MOVEMENT IS GENERALLY ACCOMPLISHED THROUGH THE COUPLING OF FREE ENERGY AVAILABLE FROM A CHEMICAL REACTION TO THE ION MOVEMENT IN THE PROCESS OF 'ACTIVE TRANSPORT'. BIOLOGICAL AND MODEL SYSTEMS STUDIED INCLUDE MEMBRANE STRUCTURE, PROPERTIES OF RECONSTITUTED MEMBRANES, IONOPHORES, ADENOSINETRIPHOSPHATASE ION PUMPS, ORGANELLE TRANSPORT OF WATER AND IONS, ENERGETICS, ENZYME BONDING, AND EFFECTS OF IONS ON MOLECULAR STRUCTURES AND INTERACTIONS. A SUCCESSFUL CHEMODIALYSIS CELL MAY OFFER CONSIDERABLE ADVANTAGES OVER PRESENT METHODS OF MEMBRANE DESALINATION, AND ON THERMODYNAMIC GROUNDS THERE IS NO REASON TO SUPPOSE THAT THE PROCESS COULD NOT COMPETE ECONOMICALLY. (KNAPP-USGS) JF - REPORT AVAILABLE FOR SALE BY SUPERINTENDENT OF DOCUMENTS, US GOVERNMENT PRINTING OFFICE, WASH, DC 20402 - PRICE $0.45. OFFICE OF SALINE WATER RESEARCH AND DEVELOPMENT PROGRESS REPORT NO 513, 1970. 33 P, 1 FIG, 20 REF, 5 APPEND. AU - Bean, Ross C AU - WAYNE ALBERS, R AD - PHILCO-FORD CORP., PHILADELPHIA, PA.; NATIONAL INSTITUTES OF HEALTH, BETHESDA, MD.; CALIFORNIA UNIV., DAVIS; HARVARD MEDICAL SCHOOL, BOSTON, MASS; AND YESHIVA UNIV., NEW YORK Y1 - 1970 PY - 1970 DA - 1970 KW - Water Resources Abstracts KW - *DESALINATION KW - *MEMBRANE PROCESSES KW - *BIOLOGICAL PROPERTIES KW - *SALINE WATER KW - DESALINATION PROCESSES KW - ELECTRODIALYSIS KW - DIALYSIS KW - OSMOSIS KW - REVERSE OSMOSIS KW - ION EXCHANGE KW - SEPARATION TECHNIQUES KW - BIOLOGICAL MEMBRANES KW - SW 1010:Saline water conversion UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18977615?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=BIOLOGICAL+ASPECTS+OF+THE+SALINE+WATER+PROBLEM&rft.au=Bean%2C+Ross+C%3BWAYNE+ALBERS%2C+R&rft.aulast=Bean&rft.aufirst=Ross&rft.date=1970-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Cochlear blood flow in response to vasodilating drugs and some related agents. AN - 85193833; pmid-4311928 JF - The Laryngoscope AU - Suga, F AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1969 SP - 1956 EP - 1979 VL - 79 IS - 11 SN - 0023-852X, 0023-852X KW - Cochlea KW - Vasodilator Agents KW - Papaverine KW - Blood Flow Velocity KW - Blood Pressure KW - Bradykinin KW - Guinea Pigs KW - Hydralazine KW - Amyl Nitrite KW - Hypoventilation KW - Animal KW - Betahistine KW - Angiotensin II KW - Regional Blood Flow KW - Histamine KW - Nicotinic Acids KW - Oxygen KW - Kallidin KW - Electrocardiography KW - Hyperventilation KW - Tetraethylammonium Compounds KW - Dipyridamole KW - Asphyxia KW - Carbon Dioxide UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85193833?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Cochlear+blood+flow+in+response+to+vasodilating+drugs+and+some+related+agents.&rft.au=Suga%2C+F%3BSnow%2C+J+B&rft.aulast=Suga&rft.aufirst=F&rft.date=1969-11-01&rft.volume=79&rft.issue=11&rft.spage=1956&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Cholinergic control of cochlear blood flow. AN - 85166942; pmid-5822991 JF - The Annals of Otology, Rhinology, and Laryngology AU - Suga, F AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1969 SP - 1081 EP - 1090 VL - 78 IS - 5 SN - 0003-4894, 0003-4894 KW - Cochlea KW - Parasympathomimetics KW - Animals KW - Scopolamine KW - Neostigmine KW - Blood Pressure KW - Guinea Pigs KW - Edrophonium KW - Regional Blood Flow KW - Bethanechol Compounds KW - Electrocardiography KW - Bradycardia KW - Pilocarpine KW - Acetylcholine KW - Potentiometry KW - Atropine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85166942?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Cholinergic+control+of+cochlear+blood+flow.&rft.au=Suga%2C+F%3BSnow%2C+J+B&rft.aulast=Suga&rft.aufirst=F&rft.date=1969-10-01&rft.volume=78&rft.issue=5&rft.spage=1081&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - The classification of respiratory viruses and their clinical manifestations. AN - 85189746; pmid-5806992 JF - The Laryngoscope AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1969 SP - 1485 EP - 1493 VL - 79 IS - 8 SN - 0023-852X, 0023-852X KW - Influenza KW - Virus Diseases KW - Respiratory Tract Infections KW - RNA Viruses KW - Tonsillitis KW - Laryngitis KW - DNA Viruses KW - Pharyngitis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85189746?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=The+classification+of+respiratory+viruses+and+their+clinical+manifestations.&rft.au=Snow%2C+J+B&rft.aulast=Snow&rft.aufirst=J&rft.date=1969-08-01&rft.volume=79&rft.issue=8&rft.spage=1485&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Diagnostic considerations in anomalous innominate arteries. AN - 85168371; pmid-4891038 JF - The Annals of Otology, Rhinology, and Laryngology AU - Seda, H J AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1969 SP - 511 EP - 517 VL - 78 IS - 3 SN - 0003-4894, 0003-4894 KW - Angiocardiography KW - Respiratory Insufficiency KW - Brachiocephalic Trunk KW - Humans KW - Intubation, Intratracheal KW - Infant, Newborn KW - Contrast Media KW - Trachea KW - Male KW - Radiography, Thoracic UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85168371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Diagnostic+considerations+in+anomalous+innominate+arteries.&rft.au=Seda%2C+H+J%3BSnow%2C+J+B&rft.aulast=Seda&rft.aufirst=H&rft.date=1969-06-01&rft.volume=78&rft.issue=3&rft.spage=511&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Adrenergic control of cochlear blood flow. AN - 85167231; pmid-4388294 JF - The Annals of Otology, Rhinology, and Laryngology AU - Suga, F AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1969 SP - 358 EP - 374 VL - 78 IS - 2 SN - 0003-4894, 0003-4894 KW - Cochlea KW - Animals KW - Sympathetic Nervous System KW - Blood Pressure KW - Sympathomimetics KW - Guinea Pigs KW - Methods KW - Guanethidine KW - Regional Blood Flow KW - Ergot Alkaloids KW - Isoproterenol KW - Vasomotor System KW - Plethysmography, Impedance KW - Phenylephrine KW - Electrocardiography KW - Norepinephrine KW - Ephedrine KW - Epinephrine KW - Time Factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85167231?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Adrenergic+control+of+cochlear+blood+flow.&rft.au=Suga%2C+F%3BSnow%2C+J+B&rft.aulast=Suga&rft.aufirst=F&rft.date=1969-04-01&rft.volume=78&rft.issue=2&rft.spage=358&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - CPAPER T1 - INDICATORS OF THE DENTIST'S ROLE AND PATIENT EXPECTATIONS T2 - American Sociological Association AN - 61738827; 69D9067 AB - Current definitions of the dentist's role were examined in the context of Hughes' notions of 'license' & 'mandate.* As now defined in formal training for the profession, the dentist is 'MD of the oral cavity,' concerned with all disorders of the mouth & their systemic relationships. However, in practice the dental role appears to be largely limited to performance of restorative care of teeth & gums. As a possible factor in discrepancies between prescriptions of the profession & actual role performance, public expectations were probed in a national survey of 1,442 American adults. Data were collected by the National Opinion Research Center in 1965 on expectations of the dentist's role as 'MD of the oral cavity' vs 'caretaker of teeth & gums.' The R's were asked whether they would go to the dentist or MD for certain conditions; & whether or not 'the dentist is trained to deal with all diseases of the mouth, or only diseases of the teeth & gums.' Findings on an index devised to measure these orientations toward the dentist showed 45% held a traditional orientation (caretaker of teeth & gums); 30% held the expanded orientation (MD of the oral cavity); & 25% were mid-point on the scale. Traditional & expanded orientation groups were compared on the basis of 7 demographic variables of education, income, age, sex, race, size of place, & geographic area. According to the findings, sex, geographic area, & size of place were variables that showed significant differences at least at the .05 level using chi square. Men more than women, rural areas more than big cities, people in the West more than in the East, were more likely to be traditionally oriented. Expectations for detection of oral cancer, an expanded role function, were examined as an issue that might cause changes in the traditional group. 66.6% of the expanded orientation group & 33.3% of the traditional group thought that the dentist should examine his patients for oral cancer. Legal definitions of the dentist's role were also analyzed. Traditional terms were used in a little over 50% of the State Laws. The case of dentistry points to the fact that license & mandate are achieved in time, & are not uniformly held in the national culture. In general, mandate tends to establish the dentist in his expanded role function, while prescriptions of licensure tend to be more restrictive. JF - American Sociological Association AU - O'Shea, Robert M AU - Fusillo, Alice E Y1 - 1969///0, PY - 1969 DA - 0, 1969 KW - EXPECTATIONS-EXPECTANCY : OF PATIENTS & THE ROLE OF THE DENTIST KW - PROFESSION : EXPECTATIONS ROLE OF THE DENTIST & PATIENT KW - ROLE : OF THE DENTIST & PATIENT EXPECTATIONS KW - Expectations/Expectancy KW - Role/Roles KW - Profession/Professions/ Professional/ Professionals/ Professionalism/ Professionalized KW - proceeding KW - 2045: sociology of health and medicine; sociology of medicine (public health) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61738827?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=American+Sociological+Association&rft.atitle=INDICATORS+OF+THE+DENTIST%27S+ROLE+AND+PATIENT+EXPECTATIONS&rft.au=O%27Shea%2C+Robert+M%3BFusillo%2C+Alice+E&rft.aulast=O%27Shea&rft.aufirst=Robert&rft.date=1969-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=American+Sociological+Association&rft.issn=&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2009-03-10 N1 - Publication note - 1969 N1 - SuppNotes - SESSION 42. N1 - Last updated - 2016-09-28 ER - TY - JOUR T1 - THE SIMULATED SITUATION: A METHODOLOGICAL NOTE AN - 60656574; 70E5467 AB - The simulated situation is a method used to elicit & record instancies of ongoing soc behavior. It is particularly useful in the study of empirical situations that would ordinarily be directly observed, but which are obstructed from our view due to infrequent occurrence, soc barriers, etc. In the study of the Ur heroin addict culture, many situations are obstructed due to the illegality of much of the addict's daily behavior. With the assistance of addict-patients at Lexington, several situations have been simulated to provide data for the analysis of addict culture. In the simulations, the participants define, act-out, & interpret the behavior & provide checks of its authenticity. Several examples are given to demonstrate both the method's utility & the effectiveness of the checks. AA. JF - Human Organization AU - Agar, Michael AD - NIMH, CLINICAL RES CENTER, LEXINGTON, KY Y1 - 1969/01// PY - 1969 DA - January 1969 SP - 322 EP - 329 VL - 28 IS - 4 SN - 0018-7259, 0018-7259 KW - METHODOLOGY : OF A SIMULATED SITUATION KW - SIMULATE : SITUATION KW - SITUATION : SIMULATED KW - SOCIAL BEHAVIOR : & SIMULATED SITUATION KW - Methodology/Methodologies/ Methodological (see also Method) KW - Situation/Situations/Situational KW - Simulate/Simulated/Simulation/ Simulator KW - Social behavior KW - article KW - 0103: methodology and research technology; methodology (conceptual & epistemological) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60656574?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+Organization&rft.atitle=THE+SIMULATED+SITUATION%3A+A+METHODOLOGICAL+NOTE&rft.au=Agar%2C+Michael&rft.aulast=Agar&rft.aufirst=Michael&rft.date=1969-01-01&rft.volume=28&rft.issue=4&rft.spage=322&rft.isbn=&rft.btitle=&rft.title=Human+Organization&rft.issn=00187259&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - HUORAY N1 - SubjectsTermNotLitGenreText - Methodology/Methodologies/ Methodological (see also Method); Simulate/Simulated/Simulation/ Simulator; Situation/Situations/Situational; Social behavior ER - TY - JOUR T1 - Squamous cell papilloma of the external auditory canal and middle ear treated with radiation therapy. AN - 85191085; pmid-5701321 JF - The Laryngoscope AU - Rogers, K A AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1968 SP - 2183 EP - 2188 VL - 78 IS - 12 SN - 0023-852X, 0023-852X KW - Ear Neoplasms KW - Human KW - Ear, Middle KW - Ear Canal KW - Middle Age KW - Case Report KW - Papilloma KW - Female UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85191085?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Squamous+cell+papilloma+of+the+external+auditory+canal+and+middle+ear+treated+with+radiation+therapy.&rft.au=Rogers%2C+K+A%3BSnow%2C+J+B&rft.aulast=Rogers&rft.aufirst=K&rft.date=1968-12-01&rft.volume=78&rft.issue=12&rft.spage=2183&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Total-body irradiation of canine lymphoma. AN - 76348188; 17387894 AB - In the continuing search for models which are potentially useful for experimental therapeutics and other radiobiological studies, spontaneous lymphoma in canines has been virtually ignored. These neoplasms closely resemble their histologic counterpart in humans with respect to anatomic sites of involvement and other features. We have examined the responsiveness of canine lymphoma to total-body irradiation, and objective remissions of disease have been observed. JF - Radiation research AU - Johnson, R E AU - Cameron, T P AU - Kinard, R AD - Radiation Branch, Cancer Chemotherapy National Service Center, and Viral Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA. Y1 - 1968/12// PY - 1968 DA - December 1968 SP - 629 EP - 632 VL - 36 IS - 3 SN - 0033-7587, 0033-7587 KW - Index Medicus KW - Space life sciences KW - Animals KW - Treatment Outcome KW - Dogs KW - Male KW - Female KW - Whole-Body Irradiation -- methods KW - Lymphoma -- diagnosis KW - Whole-Body Irradiation -- adverse effects KW - Disease Models, Animal KW - Lymphoma -- radiotherapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/76348188?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiation+research&rft.atitle=Total-body+irradiation+of+canine+lymphoma.&rft.au=Johnson%2C+R+E%3BCameron%2C+T+P%3BKinard%2C+R&rft.aulast=Johnson&rft.aufirst=R&rft.date=1968-12-01&rft.volume=36&rft.issue=3&rft.spage=629&rft.isbn=&rft.btitle=&rft.title=Radiation+research&rft.issn=00337587&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-04-24 N1 - Date created - 2007-03-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Charles Smart and the adulteration investigation of the National Board of Health. AN - 734150129; 19928334 JF - The Capital chemist AU - Miles, W D AD - National Institutes of Health Y1 - 1968/11// PY - 1968 DA - November 1968 SP - 245 EP - 247 VL - 18 IS - 8 SN - 0411-0080, 0411-0080 KW - History of medicine KW - Smart KW - Food Industry -- education KW - United States Department of Agriculture -- legislation & jurisprudence KW - Food Industry -- legislation & jurisprudence KW - Chemistry -- economics KW - Food Industry -- history KW - History, 19th Century KW - United States -- ethnology KW - Chemistry -- education KW - United States Department of Agriculture -- history KW - Chemistry -- history KW - United States Department of Agriculture -- economics KW - Food Industry -- economics KW - Research Personnel -- psychology KW - Drug Contamination -- economics KW - Government Agencies -- economics KW - Drug Contamination -- legislation & jurisprudence KW - Public Health -- education KW - Government Agencies -- history KW - Research Personnel -- legislation & jurisprudence KW - Food Contamination -- economics KW - Government Regulation -- history KW - Government Agencies -- legislation & jurisprudence KW - Public Health -- legislation & jurisprudence KW - Research Personnel -- economics KW - Food Contamination -- legislation & jurisprudence KW - Research Personnel -- education KW - Public Health -- history KW - Research Personnel -- history KW - Public Health -- economics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734150129?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Capital+chemist&rft.atitle=Charles+Smart+and+the+adulteration+investigation+of+the+National+Board+of+Health.&rft.au=Miles%2C+W+D&rft.aulast=Miles&rft.aufirst=W&rft.date=1968-11-01&rft.volume=18&rft.issue=8&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=The+Capital+chemist&rft.issn=04110080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-12-31 N1 - Date created - 2009-11-23 N1 - Date revised - 2017-01-13 N1 - People - Smart N1 - Last updated - 2017-01-18 N1 - SubjectsTermNotLitGenreText - Smart ER - TY - JOUR T1 - Closure of experimental tympanic membrane perforations. AN - 85166241; pmid-5645143 JF - The Annals of Otology, Rhinology, and Laryngology AU - Rogers, K A AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1968 SP - 66 EP - 71 VL - 77 IS - 1 SN - 0003-4894, 0003-4894 KW - Animals KW - Tympanic Membrane KW - Thioglycolates KW - Guinea Pigs KW - Cautery KW - Time Factors KW - Nitrogen Mustard Compounds KW - Phenols UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85166241?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Closure+of+experimental+tympanic+membrane+perforations.&rft.au=Rogers%2C+K+A%3BSnow%2C+J+B&rft.aulast=Rogers&rft.aufirst=K&rft.date=1968-02-01&rft.volume=77&rft.issue=1&rft.spage=66&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - SHORT-TERM IMPROVEMENT IN SCHIZOPHRENIA: THE CONTRIBUTION OF BACKGROUND FACTORS AN - 1310602310 JF - American Journal of Psychiatry Y1 - 1968/01/01/ PY - 1968 DA - 1968 Jan 01 SP - 900 CY - Washington, D.C. PB - American Psychiatric Association VL - 124 IS - 7 SN - 0002-953X KW - Psychology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1310602310?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apio&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Psychiatry&rft.atitle=SHORT-TERM+IMPROVEMENT+IN+SCHIZOPHRENIA%3A+THE+CONTRIBUTION+OF+BACKGROUND+FACTORS&rft.au=&rft.aulast=&rft.aufirst=&rft.date=1968-01-01&rft.volume=124&rft.issue=7&rft.spage=900&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Psychiatry&rft.issn=0002953X&rft_id=info:doi/ DB - Periodicals Index Online N1 - Last updated - 2013-02-25 ER - TY - JOUR T1 - Influence of diphosphopyridine nucleotide (DPN) on photodynamic effects of low concentrations of methylene blue in ascites tumor cells. AN - 84834772; 18623922 AB - When four thiazine dyes were added to ascites cell suspensions to yield 10(-4) M final concentration, the order of increasing effectiveness, for both stimulation of aerobic glycolysis in the dark and inhibition of aerobic glycolysis in the presence of added light, was thionine, methylene blue, thionine blue, and new methylene blue. After illumination, inhibition of anaerobic glycolysis occurred in the same respective dye order. Studies in depth of photodynamic effects of methylene blue on Ehrlich ascites cells revealed marked metabolic effects of light and 10(-4) M dye or lower. Diphosphopyridine nucleotide (DPN) with 5 X 10(-6) M methylene blue and light almost completely abolished the Pasteur effect after only 10 minutes' illumination of the dye-cell-coenzyme system. The ability of light, methylene blue, and exogenous DPN to specifically inhibit the Pasteur effect is consistent with the view that DPN can be important to proper functioning of the Pasteur effect mechanism. It is suggested that perfusion with some of the less toxic photosensitive dyes in combination with conventional or lasered light may result in significant selective destruction of tumor cells in vivo. JF - Journal of the National Cancer Institute AU - Hunter, J C AU - Burk, D AU - Woods, M W AD - Laboratory of Biochemistry, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014, USA. Y1 - 1967/10// PY - 1967 DA - October 1967 SP - 587 EP - 593 VL - 39 IS - 4 SN - 0027-8874, 0027-8874 KW - Enzyme Inhibitors KW - 0 KW - Phenothiazines KW - Zinc Compounds KW - NAD KW - 0U46U6E8UK KW - thionine blue KW - 6990-74-5 KW - Methylene Blue KW - T42P99266K KW - thionine KW - VTT2SAT5H0 KW - Index Medicus KW - Animals KW - Tumor Cells, Cultured KW - Phenothiazines -- pharmacology KW - Zinc Compounds -- pharmacology KW - Cell Respiration -- drug effects KW - Enzyme Inhibitors -- pharmacology KW - Time Factors KW - Methylene Blue -- pharmacology KW - Glycolysis -- drug effects KW - Carcinoma, Ehrlich Tumor -- metabolism KW - Methylene Blue -- chemistry KW - Photochemotherapy KW - NAD -- pharmacology KW - Carcinoma, Ehrlich Tumor -- drug therapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/84834772?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+National+Cancer+Institute&rft.atitle=Influence+of+diphosphopyridine+nucleotide+%28DPN%29+on+photodynamic+effects+of+low+concentrations+of+methylene+blue+in+ascites+tumor+cells.&rft.au=Hunter%2C+J+C%3BBurk%2C+D%3BWoods%2C+M+W&rft.aulast=Hunter&rft.aufirst=J&rft.date=1967-10-01&rft.volume=39&rft.issue=4&rft.spage=587&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+National+Cancer+Institute&rft.issn=00278874&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-26 N1 - Date created - 2008-07-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Tonal patterns of cochlear impairment following intense stimulation with pure tones. AN - 85192273; pmid-6026273 JF - The Laryngoscope AU - Suga, F AU - Snow, J B AU - Preston, W J AU - Glomset, J L AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1967 SP - 784 EP - 805 VL - 77 IS - 5 SN - 0023-852X, 0023-852X KW - Cochlea KW - Hearing Loss, Noise-Induced KW - Evoked Potentials KW - Guinea Pigs KW - Animal KW - Potentiometry KW - Oscillometry KW - Electrophysiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85192273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Tonal+patterns+of+cochlear+impairment+following+intense+stimulation+with+pure+tones.&rft.au=Suga%2C+F%3BSnow%2C+J+B%3BPreston%2C+W+J%3BGlomset%2C+J+L&rft.aulast=Suga&rft.aufirst=F&rft.date=1967-05-01&rft.volume=77&rft.issue=5&rft.spage=784&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Cell free filtrate transplantation of human laryngeal papilloma to dogs. AN - 85181118; pmid-6022203 JF - The Laryngoscope AU - Resler, D R AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1967 SP - 397 EP - 416 VL - 77 IS - 3 SN - 0023-852X, 0023-852X KW - Human KW - Adult KW - Dogs KW - Animal KW - Transplantation, Heterologous KW - Child KW - Laryngoscopy KW - Male KW - Female KW - Tissue Donors KW - Neoplasm Transplantation KW - Laryngeal Neoplasms KW - Papilloma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85181118?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Cell+free+filtrate+transplantation+of+human+laryngeal+papilloma+to+dogs.&rft.au=Resler%2C+D+R%3BSnow%2C+J+B&rft.aulast=Resler&rft.aufirst=D&rft.date=1967-03-01&rft.volume=77&rft.issue=3&rft.spage=397&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - KINETICS OF ADSORPTION BY ACTIVATED CARBON FROM DILUTE AQUEOUS SOLUTION AN - 18997559; 7004798 AB - THE REMOVAL OF SMALL CONCENTRATIONS OF DISSOLVED SUBSTANCES FROM LIQUIDS BY PROCESSES USING ACTIVATED CARBON CONTINUES TO HAVE BROAD AND INCREASING IMPORTANCE. THIS STUDY STEMS FROM THE PREMISE THAT DESPITE THE LONG HISTORY OF CARBON APPLICATION, KNOWLEDGE OF KINETICS AND MECHANISM OF ADSORPTION FROM LIQUID SOLUTION ARE INCOMPLETE. THE TWO BASIC MATHEMATICAL MODELS OF INTRAPARTICLE DIFFUSION KINETICS ARE ANALYZED: (1) HOMOGENEOUS DIFFUSION MODEL, (2) PORE DIFFUSION MODEL. TESTS WERE MADE OF ADSORPTION OF 2-4 DICHLOROPHENOXYACETIC ACID FROM DILUTE SOLUTION ON CARBON SUCH THAT THE RATE OF TRANSPORT IN THE ABSORBENT WAS CONTROLLING, AND DIRECT MICROANALYSIS OF ABSORBENT WAS MADE. AUTHORS CONSIDER THAT BOTH MODELS ARE LIMITING CASES LACKING EXACT PRECISE DESCRIPTION OF INTRAPARTICLE DIFFUSION MECHANISM. THE PROBABLE MECHANISM APPEARS TO INVOLVE BOTH MIGRATION OF ABSORBATE THROUGH THE POROUS CARBON WITH A HIGH ENERGY OF ACTIVATION AND DIFFUSION IN THE ADSORBENT PORES. SURFACE MIGRATION OF THE HOMOGENEOUS MODEL APPEARS SUPERIMPOSED ON IRREVERSIBLE PORE DIFFUSION MODEL EFFECTS. (D'AREZZO-TEXAS) JF - CHEMICAL ENGINEERING PROGRESS SYMPOSIUM SERIES NO 74, (PHYSICAL ADSORPTION PROCESSES AND PRINCIPLES), VOL 63, 1967. P 68-78, 10 FIG, 4 TAB, 37 REF. AU - Dedrick, Robert L AU - Beckmann, Robert B AD - NATIONAL INSTITUTES OF HEALTH, BETHESDA, MD.; AND MARYLAND UNIV., COLLEGE PARK Y1 - 1967 PY - 1967 DA - 1967 KW - Water Resources Abstracts KW - *ACTIVATED CARBON KW - *ADSORPTION KW - *DIFFUSION KW - *KINETICS KW - EQUILIBRIUM KW - ISOTHERMS KW - *ADVANCED WASTE TREATMENT KW - *DICHLOROPHENOXYACETIC ACID KW - *'HOMOGENEOUS DIFFUSION MODEL' KW - *'PORE DIFFUSION MODEL' KW - CONCENTRATION KW - DIFFUSIVITY KW - INTRAPARTICLE DIFFUSION KW - SW 3040:Wastewater treatment processes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18997559?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=KINETICS+OF+ADSORPTION+BY+ACTIVATED+CARBON+FROM+DILUTE+AQUEOUS+SOLUTION&rft.au=Dedrick%2C+Robert+L%3BBeckmann%2C+Robert+B&rft.aulast=Dedrick&rft.aufirst=Robert&rft.date=1967-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - THE CHINESE NARCOTIC ADDICT IN THE UNITED STATES AN - 60077323; 67C3947A AB - From 1935 through 1964, more than 800 Chinese M narcotic addicts were admitted to Lexington Hosp. Of this group, 137 recent M admissions were selected for study. It was found that these Chinese addicts exemplified the sojourner way of life, but that they were unsuccessful sojourners. Migrants to the US in search of wealth, they were alienated from the dominant US culture. They lived in metropolitan Chinatowns, worked in laundries or restaurants, & were separated from their fam's. At the time of their current hosp'ization for opiate addiction, these patients were an older group-3 yrs-with a long history of drug use. Evidence of the high incidence of opiate addiction among the Chinese-Amer's during the 1st half of this cent is considered. The reasons why addiction within this minority group has virtually ceased by the 1960's are discussed. HA. JF - Social Forces AU - Ball, John C AU - Lau, M P AD - NIMH, ADDICTION RES CENTER, LEXINGTON, KY & COSTLE PARK HOSP, HONG KONG Y1 - 1966/09// PY - 1966 DA - September 1966 SP - 68 EP - 72 VL - 45 IS - 1 SN - 0037-7732, 0037-7732 KW - ADDICT : NARCOTIC, CHINESE, IN THE U..S., KW - CHINA : NARCOTIC ADDICT IN THE U.S., KW - NARCOTIC : ADDICT, CHINESE, IN THE U.S., KW - UNITED STATES : THE CHINESE NARCOTIC ADDICT IN, KW - Narcotic/Narcotics KW - China/Chinese KW - United States/US KW - Addict/Addicts/Addicted/Addictive/ Addiction KW - article KW - 2147: social problems and social welfare; sociology of crime & victimology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60077323?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Forces&rft.atitle=THE+CHINESE+NARCOTIC+ADDICT+IN+THE+UNITED+STATES&rft.au=Ball%2C+John+C%3BLau%2C+M+P&rft.aulast=Ball&rft.aufirst=John&rft.date=1966-09-01&rft.volume=45&rft.issue=1&rft.spage=68&rft.isbn=&rft.btitle=&rft.title=Social+Forces&rft.issn=00377732&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-10-30 N1 - Last updated - 2016-09-28 N1 - CODEN - SOFOAP N1 - SubjectsTermNotLitGenreText - Addict/Addicts/Addicted/Addictive/ Addiction; China/Chinese; Narcotic/Narcotics; United States/US ER - TY - JOUR T1 - NARCOTICS, NEGROES AND THE SOUTH AN - 60074421; 67C3948 AB - Sociol'al literature for 30 yrs has shown an overrepresentation of Negroes in the known addict pop. This study of addict admissions to the USPH service hosp's at Lexington & Fort Worth shows that there was a dramatic increase in Negro admissions in 1950. Although Negro narcotic addiction is almost entirely confined to northern metropolitan areas, what Negro addiction exists in the South is almost entirely from a few big cities. White addicts from the southern states, on the other hand, are chiefly from Ru areas. Negro addicts from the South are younger than white addicts, but northern white & Negro addicts are the same age. HA. JF - Social Forces AU - Bates, William M AD - NIMH, ADDICTION RES CENTER, LEXINGTON, KY Y1 - 1966/09// PY - 1966 DA - September 1966 SP - 61 EP - 67 VL - 45 IS - 1 SN - 0037-7732, 0037-7732 KW - NARCOTIC : NEGROES & THE SOUTH, KW - NEGRO : NARCOTICS & THE SOUTH, KW - SOUTH : NARCOTICS & NEGROES, KW - South/Southern KW - Negro/Negroes KW - Narcotic/Narcotics KW - article KW - 2147: social problems and social welfare; sociology of crime & victimology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60074421?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Forces&rft.atitle=NARCOTICS%2C+NEGROES+AND+THE+SOUTH&rft.au=Bates%2C+William+M&rft.aulast=Bates&rft.aufirst=William&rft.date=1966-09-01&rft.volume=45&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=Social+Forces&rft.issn=00377732&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-10-30 N1 - Last updated - 2016-09-28 N1 - CODEN - SOFOAP N1 - SubjectsTermNotLitGenreText - Narcotic/Narcotics; Negro/Negroes; South/Southern ER - TY - JOUR T1 - Multiplicity and familial incidence of carotid body and glomus jugulare tumors. AN - 85172977; pmid-4286420 JF - The Annals of Otology, Rhinology, and Laryngology AU - Resler, D R AU - Snow, J B AU - Williams, G R AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1966 SP - 114 EP - 122 VL - 75 IS - 1 SN - 0003-4894, 0003-4894 KW - Humans KW - Middle Aged KW - Female KW - Carotid Body Tumor KW - Paraganglioma, Extra-Adrenal UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85172977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.atitle=Multiplicity+and+familial+incidence+of+carotid+body+and+glomus+jugulare+tumors.&rft.au=Resler%2C+D+R%3BSnow%2C+J+B%3BWilliams%2C+G+R&rft.aulast=Resler&rft.aufirst=D&rft.date=1966-03-01&rft.volume=75&rft.issue=1&rft.spage=114&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+Otology%2C+Rhinology%2C+and+Laryngology&rft.issn=00034894&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - The clinical attitude. AN - 85146830; pmid-5904055 JF - ASHA AU - Snow, J B AD - National Institute on Deafness and other Communication Disorders, Bethesda, Maryland 20892, USA. PY - 1966 SP - 87 EP - 88 VL - 8 IS - 3 SN - 0001-2475, 0001-2475 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85146830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=ASHA&rft.atitle=The+clinical+attitude.&rft.au=Snow%2C+J+B&rft.aulast=Snow&rft.aufirst=J&rft.date=1966-03-01&rft.volume=8&rft.issue=3&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=ASHA&rft.issn=00012475&rft_id=info:doi/ LA - English DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Forssman antigen content of guinea pig hepatomas induced by diethylnitrosamine: a quantitative approach to the search for tumor-specific antibodies. AN - 84485619; 18630327 AB - The Forssman antigen content of diethylnitrosamine-induced guinea pig hepatomas was found to be greater than that of either autogenous or allogeneic guinea pig liver. The autogenous normal liver was obtained from guinea pigs before tumor induction, and comparison of normal and neoplastic tissues was based on the capacity of these tissues to inhibit (absorb) the hemolytic activity of rabbit antitumor serum. A method is presented for distinguishing quantitative from qualitative antigenic differences in the search for tumor-specific antigens. The results of these experiments indicate that, in the absence of strict quantitation, quantitative differences may be mistaken for qualitative differences. JF - Journal of the National Cancer Institute AU - Crisler, C AU - Rapp, H J AU - Weintraub, R M AU - Borsos, T AD - Immunochemistry Section, Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Y1 - 1966/03// PY - 1966 DA - March 1966 SP - 529 EP - 538 VL - 36 IS - 3 SN - 0027-8874, 0027-8874 KW - Antibodies, Neoplasm KW - 0 KW - Antigens, Neoplasm KW - Carcinogens KW - Diethylnitrosamine KW - 3IQ78TTX1A KW - Forssman Antigen KW - 9013-60-9 KW - Index Medicus KW - Animals KW - Guinea Pigs KW - Forssman Antigen -- analysis KW - Liver Neoplasms, Experimental -- immunology KW - Antibodies, Neoplasm -- analysis KW - Antigens, Neoplasm -- analysis KW - Liver Neoplasms, Experimental -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/84485619?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+National+Cancer+Institute&rft.atitle=Forssman+antigen+content+of+guinea+pig+hepatomas+induced+by+diethylnitrosamine%3A+a+quantitative+approach+to+the+search+for+tumor-specific+antibodies.&rft.au=Crisler%2C+C%3BRapp%2C+H+J%3BWeintraub%2C+R+M%3BBorsos%2C+T&rft.aulast=Crisler&rft.aufirst=C&rft.date=1966-03-01&rft.volume=36&rft.issue=3&rft.spage=529&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+National+Cancer+Institute&rft.issn=00278874&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-27 N1 - Date created - 2008-07-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - INTERACTION SEQUENCES AN - 60619165; 67C3458 AB - Some studies of the soc behavior of children are used to illustrate 2 methods for investigating interaction sequences. One method is that of multivariate informational analysis; the other involves a transition probability model. The procedures are applied to study affectional behavior among children in several diff groups, both normal & disturbed, & under diverse situations. Beyond its aim of demonstrating the utility of the techniques, the paper suggests processes of control & org by which situational & personal variables influence soc interaction. The methods & concepts are thought to be applicable to the study of the temporal chaining of events within other groups & within paired relationships. HA. JF - Journal of Personality and Social Psychology AU - Raush, Harold L AD - NIMH, BETHESDA, MD Y1 - 1965/10// PY - 1965 DA - October 1965 SP - 487 EP - 499 VL - 2 IS - 4 SN - 0022-3514, 0022-3514 KW - BEHAVIOR : OF CHILDREN, RE INTERACTION SEQUENCES KW - CHILD : SOCIAL BEHAVIOR OF, KW - INTERACTION : SEQUENCES, KW - MULTI- : INFORMATIONAL ANALYSIS, RE CHILDREN'S BEHAVIOR, KW - Behavior/Behavioral KW - Child/Children/Childhood KW - Interaction/Interactions/ Interactional/ Interactionalist/ Interactionalism/ Interactive KW - Multi-/Multiple KW - article KW - 0312: social psychology; personality & culture UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60619165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Personality+and+Social+Psychology&rft.atitle=INTERACTION+SEQUENCES&rft.au=Raush%2C+Harold+L&rft.aulast=Raush&rft.aufirst=Harold&rft.date=1965-10-01&rft.volume=2&rft.issue=4&rft.spage=487&rft.isbn=&rft.btitle=&rft.title=Journal+of+Personality+and+Social+Psychology&rft.issn=00223514&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JPSPB2 N1 - SubjectsTermNotLitGenreText - Behavior/Behavioral; Child/Children/Childhood; Interaction/Interactions/ Interactional/ Interactionalist/ Interactionalism/ Interactive; Multi-/Multiple ER - TY - JOUR T1 - Ultrastructure of Mycoplasma hominis. AN - 84155139; 16562016 AB - Anderson, Douglas R. (National Cancer Institute, Bethesda, Md.), and Michael F. Barile. Ultrastructure of Mycoplasma hominis. J. Bacteriol. 90:180-192. 1965.-Both thin-sectioning and negative staining were used in an electron microscopic study of the morphology of pleuropneumonia-like organism (PPLO) strain HEp-2 (Mycoplasma hominis, type I) grown in an artificial liquid medium. The morphology is quite variable and seems to depend, in part, on the age of the culture. The smallest form observed ("elementary body") is 80 to 100 mmu in diameter. The internal components of the larger PPLO cells (0.5 to 1 mu) are variable-some have ribosomelike granules and nuclear areas of netlike strands, and others have only irregular dense areas in a pale groundplasm. Some of the forms have dense cytoplasmic bodies which look much like elementary bodies. Others have vacuoles which may contain structures which look like smaller organisms. Especially in older cultures, very large (10 mu) vacuolated organisms are seen, probably corresponding to the "large bodies" described by light microscopists. Filamented forms are also seen. These observations suggest several possible modes of reproduction, each perhaps operating under different cultural conditions or at different ages of the culture. JF - Journal of bacteriology AU - Anderson, D R AU - Barile, M F AD - Laboratory of Viral Carcinogenesis, National Cancer Institute, Bethesda, Maryland. Y1 - 1965/07// PY - 1965 DA - July 1965 SP - 180 EP - 192 VL - 90 IS - 1 SN - 0021-9193, 0021-9193 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/84155139?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+bacteriology&rft.atitle=Ultrastructure+of+Mycoplasma+hominis.&rft.au=Anderson%2C+D+R%3BBarile%2C+M+F&rft.aulast=Anderson&rft.aufirst=D&rft.date=1965-07-01&rft.volume=90&rft.issue=1&rft.spage=180&rft.isbn=&rft.btitle=&rft.title=Journal+of+bacteriology&rft.issn=00219193&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-05-26 N1 - Date created - 2006-05-26 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Biophys Biochem Cytol. 1957 Nov 25;3(6):1043-8 [13481037] J Biophys Biochem Cytol. 1958 Jul 25;4(4):349-64 [13563541] Z Naturforsch B. 1958 Sep;13B(9):597-605 [13604673] Nature. 1961 Jul 8;191:190-1 [13765826] Biochim Biophys Acta. 1959 Jul;34:103-10 [13804200] J Bacteriol. 1960 Feb;79:267-76 [13819408] Ann N Y Acad Sci. 1960 Jan 15;79:312-25 [13824926] J Biophys Biochem Cytol. 1960 Jul;7:697-716 [13827900] J Bacteriol. 1962 Jul;84:130-6 [13865001] J Cell Biol. 1963 Apr;17:19-58 [13975866] J Cell Biol. 1963 Apr;17:208-12 [13986422] Exp Cell Res. 1963 May;30:593-6 [13991728] J Bacteriol. 1963 Aug;86:195-206 [14058941] Stain Technol. 1964 Mar;39:111-4 [14127791] J Natl Cancer Inst. 1964 Sep;33:547-56 [14207862] J Bacteriol. 1964 Sep;88:727-44 [14208513] Nature. 1965 Jan 23;205:371-2 [14243415] J Ultrastruct Res. 1960 Feb;3:282-301 [14405991] Antonie Van Leeuwenhoek. 1960;26:9-22 [14405992] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - PREVENTIVE PSYCHIATRY AND FAMILY PLANNING AN - 60603269; 65B6530 AB - Genetic, gestational, & postnatal factors related to mental illness & retardation appropriately bring the psychiatrist's attention to focus on fam planning. Maternal deprivation, abortion, postpartum psychosis, & the fate of the unwanted child are some of the problems encountered which challenge researcher & clinician alike. Several studies related to these issues are cited. Effective fam planning, including child spacing, reflects an important capacity on the part of parents to master their own present & future environment. Can this competence be developed quickly & humanely for large numbers of people with the help of technological advances in BC? The mental health professional, with the help of many others, must include consideration of pop pressures, changing soc mores, & technological change in his effort to deal comprehensively with factors affecting the emotional life of individuals. AA. JF - Journal of Marriage and the Family AU - Lieberman, E James AD - NIMH, BETHESDA, MD Y1 - 1964/11// PY - 1964 DA - November 1964 SP - 471 EP - 477 VL - 26 IS - 4 SN - 0022-2445, 0022-2445 KW - FAMILY : & PREVENTIVE PSYCHIATRY, KW - PREVENTION : PSYCHIATRY & FAMILY PLANNING, KW - PSYCHIATRY : PREVENTIVE, & FAMILY PLANNING, KW - Psychiatry/Psychiatric KW - Prevention/Preventive KW - Family/Families KW - article KW - 1941: the family and socialization; sociology of the family UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60603269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Marriage+and+the+Family&rft.atitle=PREVENTIVE+PSYCHIATRY+AND+FAMILY+PLANNING&rft.au=Lieberman%2C+E+James&rft.aulast=Lieberman&rft.aufirst=E&rft.date=1964-11-01&rft.volume=26&rft.issue=4&rft.spage=471&rft.isbn=&rft.btitle=&rft.title=Journal+of+Marriage+and+the+Family&rft.issn=00222445&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JMFAA6 N1 - SubjectsTermNotLitGenreText - Family/Families; Prevention/Preventive; Psychiatry/Psychiatric ER - TY - JOUR T1 - CRISIS OF A PROFESSION: THE PROFESSIONAL ORIENTATION OF YOUTH & BUREAUCRATIC CAREERS, RESULTS OF A PILOT STUDY TT - CRISI DI UNA PROFESSIONE: GLI ORIENTAMENTI PROFESSIONALE DEI GIOVA AN - 60593741; 66C1599 AB - The econ changes in Italy during the last decade have resulted in a decrease in the N of young men with U degrees going into public administration careers, & a decrease in the quality of applicants. Tables giving the %'s of gov employees in general & higher officials of the state, esp re their geographic zone of birth, show a preponderance of those born in the south. 3 factors are evaluated as reasons for the diminished interest of youngsters in bur'tic careers: (1) econ motives-low pay, (2) certain negative characteristics of civil service, & (3) low prestige of employment by the gov in general. Data originate in a pilot survey undertaken in 1962. Factors in professional orientation include satisfaction received from the type of activity chosen, increase in remuneration & indirect econ benefits, advancement opportunities, autonomy & independence, stability & security, & prestige. The professions are analyzed in order of preference & the relationship between professional preference & father's profession is examined. The image of the bur'- tic profession is found to be negative: no flexibility in advancement, no individual initiative possible, too much monotonous routine, & conformism. %o's of positive aspects of bur'tic careers are compared with negative aspects. S's were questioned re their source of information on bur'tic careers, & it was found that there is a general lack of data on bur'cy, the MM supplying most of the information. It is demonstrated that increase in remuneration prestige & changes in the system of advancement would increase the attraction of civil service careers. M. Maxfield. JF - Rassegna Italiana di Sociologia AU - Sani, Giacomo AD - NI E LE CARRIERE BUROCRATICHE NEI RISULTATI DI UNO STUDIO PILOTA Y1 - 1963/04// PY - 1963 DA - April 1963 SP - 353 EP - 385 VL - 4 IS - 2 SN - 0486-0349, 0486-0349 KW - BUREAUCRACY : CAREERS & PROFESSIONAL ORIENTATION OF YOUTH IN ITALY, KW - CAREER : BUREAUCRATIC, & PROFESSIONAL ORIENTATION OF YOUTH IN ITALY, KW - ITALY : PROFESSIONAL ORIENTATION OF YOUTH & BUREAUCRATIC CAREERS IN, KW - PROFESSION : ORIENTATION OF YOUTH & BUREAUCRATIC CAREERS IN ITALY, KW - YOUTH : PROFESSIONAL ORIENTATION OF TO BUREAUCRATIC CAREERS IN ITALY, KW - Youth/Youths/Youthful KW - Bureaucracy/Bureaucracies/ Bureaucrat/ Bureaucratic KW - Profession/Professions/ Professional/ Professionals/ Professionalism/ Professionalized KW - Italy/Italian/Italians KW - Career/Careers KW - article KW - 1939: the family and socialization; adolescence & youth UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60593741?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Rassegna+Italiana+di+Sociologia&rft.atitle=CRISIS+OF+A+PROFESSION%3A+THE+PROFESSIONAL+ORIENTATION+OF+YOUTH+%26amp%3B+BUREAUCRATIC+CAREERS%2C+RESULTS+OF+A+PILOT+STUDY&rft.au=Sani%2C+Giacomo&rft.aulast=Sani&rft.aufirst=Giacomo&rft.date=1963-04-01&rft.volume=4&rft.issue=2&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Rassegna+Italiana+di+Sociologia&rft.issn=04860349&rft_id=info:doi/ LA - Italian DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - RITSBL N1 - SubjectsTermNotLitGenreText - Bureaucracy/Bureaucracies/ Bureaucrat/ Bureaucratic; Career/Careers; Italy/Italian/Italians; Profession/Professions/ Professional/ Professionals/ Professionalism/ Professionalized; Youth/Youths/Youthful ER - TY - JOUR T1 - ANTIMICROBIAL ACTIVITY OF MARINE WATERS. 1 I. MACROMOLECULAR NATURE OF ANTISTAPI-IYLOCOCCAL FACTOR AN - 1827903718; PQ0003642522 AB - Water from Vineyard Sound, Mass., has a rapid bactericidal activity against both penicillin-sensitive and -resistant strains of Staphylococcus aureus but under the conditions of these experiments, exhibits no anticoliform effect. It has been demonstrated that the active factor is a large, non-dialyzable, autoclave-labile molecule. The preponderance of gram-negative bacteria in the sea is discussed in light of the above findings. JF - Limnology and Oceanography AU - Saz, Arthur K AU - Watson, Stanley AU - Brown, Sarah R AU - Lowery, Dolores L AD - From the U. S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, Md. Y1 - 1963/04// PY - 1963 DA - April 1963 SP - 63 EP - 67 PB - Association for the Sciences of Limnology and Oceanography VL - 8 IS - 1 SN - 0024-3590, 0024-3590 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Aqualine Abstracts; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Vineyards KW - Marine KW - Bacteria KW - Antimicrobial activity KW - Macromolecules KW - Limnology KW - Strains KW - Strain KW - Gram-negative bacteria KW - Sound KW - ANW, USA, Massachusetts, Martha's Vineyard, Vineyard Sound KW - Staphylococcus aureus KW - Bactericidal activity KW - AQ 00001:Water Resources and Supplies KW - A 01340:Antibiotics & Antimicrobials KW - SW 0810:General KW - Q1 08481:Productivity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827903718?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Limnology+and+Oceanography&rft.atitle=ANTIMICROBIAL+ACTIVITY+OF+MARINE+WATERS.+1+I.+MACROMOLECULAR+NATURE+OF+ANTISTAPI-IYLOCOCCAL+FACTOR&rft.au=Saz%2C+Arthur+K%3BWatson%2C+Stanley%3BBrown%2C+Sarah+R%3BLowery%2C+Dolores+L&rft.aulast=Saz&rft.aufirst=Arthur&rft.date=1963-04-01&rft.volume=8&rft.issue=1&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=Limnology+and+Oceanography&rft.issn=00243590&rft_id=info:doi/10.4319%2Flo.1963.8.1.0063 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Strains; Vineyards; Macromolecules; Antimicrobial activity; Gram-negative bacteria; Sound; Bactericidal activity; Bacteria; Limnology; Strain; Staphylococcus aureus; ANW, USA, Massachusetts, Martha's Vineyard, Vineyard Sound; Marine DO - http://dx.doi.org/10.4319/lo.1963.8.1.0063 ER - TY - JOUR T1 - PARENTAL INTEREST AND CHILDREN'S SELF-CONCEPTIONS AN - 60579094; 63A6912 AB - Studies examining the relationship of parental att's to the personality of the child have often neglected the factor of parental interest. The relationship of parental interest to the child's level of self-esteem is examined in a study of HSch juniors & seniors in 10 Sch's. 3 indicators of parental interest, representing recurrent points of contact between parent & child, are utilized. Though great or moderate amounts of parental interest are not associated with substantial diff's in self-esteem, extreme parental in diff. is clearly related to low self-esteem. There is evidence to suggest that such extreme parental in diff. may be even more closely associated with low self-esteem than punitive reactions on the part of the parents. AA. JF - Sociometry AU - Rosenberg, Morris AD - NIMH, BETHESDA, MD Y1 - 1963/03// PY - 1963 DA - March 1963 SP - 35 EP - 49 VL - 26 IS - 1 KW - CHILD : SELF-ESTEEM OF, & PARENTAL INTEREST, KW - CONCEPT : SELF- OF CHILDREN, & PARENTAL INTEREST, KW - ESTEEM : OF CHILDREN & PARENTAL INTEREST, KW - INTEREST : PARENTAL, & CHILDREN'S SELF-ESTEEM, KW - PARENT : INTEREST & CHILDRENS SELF-ESTEEM, KW - SELF : -ESTEEM OF CHILDREN & PARENTAL INTEREST, KW - Esteem KW - Interest/Interests KW - Child/Children/Childhood KW - Self KW - Concept/Concepts/Conception/Conceptual/ Conceptualization KW - Parent/Parents/Parental KW - article KW - 1938: the family and socialization; sociology of the child UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60579094?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Sociometry&rft.atitle=PARENTAL+INTEREST+AND+CHILDREN%27S+SELF-CONCEPTIONS&rft.au=Rosenberg%2C+Morris&rft.aulast=Rosenberg&rft.aufirst=Morris&rft.date=1963-03-01&rft.volume=26&rft.issue=1&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=Sociometry&rft.issn=&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - SOCIAQ N1 - SubjectsTermNotLitGenreText - Child/Children/Childhood; Concept/Concepts/Conception/Conceptual/ Conceptualization; Esteem; Interest/Interests; Parent/Parents/Parental; Self ER - TY - JOUR T1 - SOCIAL CONTEXT AND SYMPTOM FLUCTUATION AN - 60544915; 64B0018 AB - A study of whether or not 25 patients (P's) on an open, chronic, psychiatric ward fluctuated together in terms of intensity of psychotic illness. The method used was one of rating the level of manifest illness of each P, each day, by a, number from 0 - 5. Illness was defined in a separate symptom description for each P. Each P's series of scores was v'ed over time with each other P's after about 8 months of ratings & the coefficients studied for significance & meaningfulness. Race & level of educ seemed to be signif variables in the linking of P's re fluctuations of manifest illness. Lower educated white P's tended to become sicker when the Negro P's were healthier, & vice versa. Other variables are discussed. The conclusion is that P's did, in fact, tend to fluctuate together, in specific pairs & groups, & that the various combinations were not accidental. The concept of `symptom linkage,' & the broader concept of the `topology' of symptom fluctuation within a soc context, in the fam as well as on the ward & elsewhere, seems to be an area for study which can be treated statistically, as well as by participant observation, with increasing validity. AA. JF - Psychiatry AU - Kellam, Sheppard AU - CHASSEN, J B AD - NIMH, BETHESDA, MD, & HOFFMAN-LAROCHE, INC, NUTLEY, NJ Y1 - 1962/11// PY - 1962 DA - November 1962 SP - 370 EP - 381 VL - 25 IS - 4 SN - 0033-2747, 0033-2747 KW - CONTEXT : SOCIAL & SYSTEM FLUCTUATION, KW - FLUCTUATION : SYSTEM & SOCIAL CONTEXT, KW - PATIENT : PSYCHIATRIC, SYSTEM FLUCTUATION OF, KW - WARD : PSYCHIATRIC, PATIENTS SYSTEM FLUCTUATION OF, KW - Patient/Patients KW - Fluctuation/Fluctuations KW - Ward KW - Context/Contexts/Contextual/ Contextualist KW - article KW - 2046: sociology of health and medicine; social psychiatry (mental health) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60544915?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychiatry&rft.atitle=SOCIAL+CONTEXT+AND+SYMPTOM+FLUCTUATION&rft.au=Kellam%2C+Sheppard%3BCHASSEN%2C+J+B&rft.aulast=Kellam&rft.aufirst=Sheppard&rft.date=1962-11-01&rft.volume=25&rft.issue=4&rft.spage=370&rft.isbn=&rft.btitle=&rft.title=Psychiatry&rft.issn=00332747&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - CODEN - PSYCAB N1 - SubjectsTermNotLitGenreText - Context/Contexts/Contextual/ Contextualist; Fluctuation/Fluctuations; Patient/Patients; Ward ER - TY - JOUR T1 - CAGE AND KENNEL WASTE WATER AN - 19003277; 7110100 AB - THE NATIONAL INSTITUTES OF HEALTH IS PLANNING A LABORATORY-ANIMAL COLONY IN AN UNSEWERED AREA. THE WASTE WATER FROM THE COLONY WILL REQUIRE TREATMENT ON THE SITE. THE WASTE WATER FROM CAGE CLEANING AND KENNEL CLEANING IS EXPECTED TO REPRESENT A LARGE PERCENTAGE OF THE TOTAL SEWAGE OF THE COLONY. A STUDY OF THE VOLUME AND CHARACTER OF THE WASTE WATER OF A SIMILAR ANIMAL COLONY TO THE ONE PORPOSED WAS MADE. MECHANICAL WASHERS ARE USED TO CLEAN THE CAGES. EACH WASHER CONTAINS A 1,000-GALLON RECIRCULATING WASH WATER TANK AND A 500-GALLON, RECIRCULATING, RINSE WATER TANK. EXCESS WATER OVERFLOWS TO THE SEWERS. SAMPLES OF THE OVERFLOW WERE COLLECTED AT 30-MINUTE INTERVALS. THESE SAMPLES WERE COMPOSITED IN PROPORTION TO THE QUANTITY OF WASTE WATER FROM EACH MACHINE. THE BOD IN THE OVERFLOW WAS LESS THAN THAT IN THE WASTE WATER DRAINED FROM THE TANKS. THE PH WAS 11.0 AND THE TEMPERATURE WAS 140 TO 160F OF THE WASTE WATER. THE BOD, TOTAL SOLIDS, AND VOLATILE SOLIDS OF THE WASTE WATER FROM HOSING OF THE PENS WAS APPROXIMATELY THREE TIMES PER UNIT VOLUME AS THAT FOUND IN DOMESTIC SEWAGE. THE WASTE WATER HAS A SHARP, UNPLEASNAT ODOR, WHICH MIGHT CONSTITUTE A PROBLEM WHEN IT IS TREATED IN A POPULATION AREA. (HAZEN-IOWA STATE) JF - THIS WAS REPORTED AS 'NIH DETERGENT FOR MECHANICAL WASHING OF LABORATORY GLASSWARE AND ANIMAL CAGES' SANITARY ENGINEERING BRANCH PROJECT 136 (1955). JOURNAL WATER POLLUTION CONTROL FEDERATION, VOL 34, NO 1, P. 40-43, JAN, 1962. 1 FIG, 5 TAB, 2 REF. AU - Jaworski, Na AU - HICKEY, JLS AD - NATIONAL INSTITUTES OF HEALTH, BETHESDA, MD. DIV OF RESEARCH SERVICES Y1 - 1962/01// PY - 1962 DA - Jan 1962 KW - Water Resources Abstracts KW - *WASTE WATER DISPOSAL KW - *BIOCHEMICAL OXYGEN DEMAND KW - WASTE WATER KW - WATER ANALYSIS KW - ANIMAL WASTES(WILDLIFE) KW - WASTE IDENTIFICATION KW - WASTE DILUTION KW - WASTE WATER TREATMENT KW - LABORATORY ANIMALS KW - *WASTE WATER PRODUCTION KW - TOTAL SOLIDS KW - VOLATILE SOLIDS KW - COMPOSITE SAMPLES KW - CAGE CLEANING WASTES KW - KENNEL KW - SW 3040:Wastewater treatment processes KW - SW 3010:Identification of pollutants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19003277?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=CAGE+AND+KENNEL+WASTE+WATER&rft.au=Jaworski%2C+Na%3BHICKEY%2C+JLS&rft.aulast=Jaworski&rft.aufirst=Na&rft.date=1962-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - ON THE USE OF CARBONIC ANHYDRASE IN CARBONATE AND AMINE BUFFERS FOR CO2 EXCHANGE IN MANOMETRIC VESSELS, ATOMIC SUBMARINES, AND INDUSTRIAL CO2 SCRUBBERS AN - 876226633; 14906531 JF - Annals of the New York Academy of Sciences AU - Burk, Dean AD - National Institutes of Health, Public Health Service, Bethesda, Md., and the Max Planck Institute for Cell Physiology, Berlin-Dahlem, German Federal Republic Y1 - 1961/06// PY - 1961 DA - Jun 1961 SP - 372 EP - 400 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 92 IS - 2 SN - 0077-8923, 0077-8923 KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Sustainability Science Abstracts KW - submarines KW - buffers KW - Scrubbers KW - Carbonic anhydrase KW - Carbonates KW - Air pollution control KW - Pollution control equipment KW - Carbon dioxide KW - Amines KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development KW - Q2 09301:Surface vehicles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876226633?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=ON+THE+USE+OF+CARBONIC+ANHYDRASE+IN+CARBONATE+AND+AMINE+BUFFERS+FOR+CO2+EXCHANGE+IN+MANOMETRIC+VESSELS%2C+ATOMIC+SUBMARINES%2C+AND+INDUSTRIAL+CO2+SCRUBBERS&rft.au=Burk%2C+Dean&rft.aulast=Burk&rft.aufirst=Dean&rft.date=1961-06-01&rft.volume=92&rft.issue=2&rft.spage=372&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/10.1111%2Fj.1749-6632.1961.tb44988.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Number of references - 1 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Carbonates; Carbonic anhydrase; Amines; Carbon dioxide; submarines; Scrubbers; buffers; Air pollution control; Pollution control equipment DO - http://dx.doi.org/10.1111/j.1749-6632.1961.tb44988.x ER - TY - JOUR T1 - BIOCHEMICAL BASIS FOR THE TOXICITY OF PENTACHLOROPHENOL. AN - 82104849; 16590025 JF - Proceedings of the National Academy of Sciences of the United States of America AU - Weinbach, E C AD - UNITED STATES DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE, PUBLIC HEALTH SERVICE, NATIONAL INSTITUTES OF HEALTH, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES,BETHESDA, MARYLAND. Y1 - 1957/05/15/ PY - 1957 DA - 1957 May 15 SP - 393 EP - 397 VL - 43 IS - 5 SN - 0027-8424, 0027-8424 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/82104849?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=BIOCHEMICAL+BASIS+FOR+THE+TOXICITY+OF+PENTACHLOROPHENOL.&rft.au=Weinbach%2C+E+C&rft.aulast=Weinbach&rft.aufirst=E&rft.date=1957-05-15&rft.volume=43&rft.issue=5&rft.spage=393&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.issn=00278424&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-06-01 N1 - Date created - 2006-06-01 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Biol Chem. 1954 Oct;210(2):545-50 [13211591] Exp Parasitol. 1956 May;5(3):276-84 [13317948] J Biol Chem. 1956 Aug;221(2):609-18 [13357455] Arch Biochem Biophys. 1956 Sep;64(1):129-43 [13363421] Nature. 1956 Dec 1;178(4544):1225-6 [13387667] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - SOCIO-ECONOMIC STATUS AND PARTICIPATION IN THE POLIOMYELITIS VACCINE TRIAL AN - 60576371; 195700929 AB - A study of the relationship between SES and parental decision to grant or refuse permission for their children to receive Salk polio vaccine in the 1954 trial. Data are obtained from interviews with 130 mothers of 2nd grade children in 5 schools in a Virginia county which is partially suburban to Washington, DC & partly Ru. R's are separated into 3 groups on basis of husband's educ & occup, & wife's educ. It is discovered that 86% of the highest, 84% of the middle, and 43% of the lowest SES level consented for their children to particpate in the vaccine trial. Motivational & informational factors thought to explain the differential participation by SES are investigated. Most important motivating factor both for those who gave & who refused permission is concern for child's health. For those allowing participation, belief in efficacy of vaccine was most frequent motivation, for others, no proof of worth of vaccine, belief that it is unsafe, & child's physical condition were main reasons for refusal. More high than low status parents: (1) practiced health measures thought by them to lessen chance of polio; (2) had close friend or relative known to have had the disease; (3) had early awareness of vaccine tests; & (4) talked with neighbors, friends, & physicians about trial. It is suggested that the diff's in participation by SES can be accounted for through the basic value orientations of the groups, as reflected in the different informational & motivational factors. W. F. Kenkel. JF - American Sociological Review AU - Deasy, Leila C AD - National Institute of Mental Health Y1 - 1956/04// PY - 1956 DA - April 1956 SP - 185 EP - 191 VL - 21 IS - 2 SN - 0003-1224, 0003-1224 KW - Poliomyelitis KW - Socioeconomic Status KW - Health Behavior KW - Vaccination KW - Value Orientations KW - Sociodemographic Factors KW - article KW - 2045: sociology of health and medicine; sociology of medicine & health care UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60576371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Sociological+Review&rft.atitle=SOCIO-ECONOMIC+STATUS+AND+PARTICIPATION+IN+THE+POLIOMYELITIS+VACCINE+TRIAL&rft.au=Deasy%2C+Leila+C&rft.aulast=Deasy&rft.aufirst=Leila&rft.date=1956-04-01&rft.volume=21&rft.issue=2&rft.spage=185&rft.isbn=&rft.btitle=&rft.title=American+Sociological+Review&rft.issn=00031224&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2007-04-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Socioeconomic Status; Health Behavior; Vaccination; Poliomyelitis; Value Orientations; Sociodemographic Factors ER - TY - JOUR T1 - CONVERSATIONAL MASS SPECTRAL RETRIEVAL SYSTEM AND ITS USE AS AN AID IN STRUCTURE DETERMINATION AN - 19070112; 7304829 AB - AN INTERACTIVE, CONVERSATIONAL MASS SPECTRAL RETRIEVAL SYSTEM CONSISTING OF A COLLECTION OF COMPUTER PROGRAMS DESIGNED TO GIVE IMMEDIATE RETRIEVAL OF MASS SPECTRAL DATA IS DESCRIBED. THE SYSTEM OPTIONS INCLUDE A PEAK/INTENSITY SEARCH, A MOLECULAR WEIGHT SEARCH, A COMPLETE MOLECULAR FORMULA SEARCH, AN IMBEDDED MOLECULAR FORMULA SEARCH, AND PRINTOUT OF THE PEAKS AND INTENSITIES OF THE ENTIRE SPECTRUM. THE PROGRAMS USED TO GENERATE AND SEARCH THE FILES, AS WELL AS THE FILE STRUCTURE, ARE DESCRIBED. (BYRD-BATTELLE) JF - ANALYTICAL CHEMISTRY, VOL 44, NO 12, P 1951-1961, OCTOBER 1972. 11 FIG, 9 TAB, 17 REF. AU - Heller AD - NATIONAL INSTITUTES OF HEALTH, BETHESDA, MD. DIV. OF COMPUTER RESEARCH AND TECHNOLOGY Y1 - 1951/10// PY - 1951 DA - Oct 1951 KW - Water Resources Abstracts KW - *DATA STORAGE AND RETRIEVAL KW - *DESIGN CRITERIA KW - AUTOMATION KW - COMPUTERS KW - COMPUTER PROGRAMS KW - CONTROL SYSTEMS KW - POLLUTANT IDENTIFICATION KW - PHYSICAL PROPERTIES KW - *MASS SPECTRA KW - MOLECULAR WEIGHT KW - CHEMICAL STRUCTURE KW - MOLECULAR STRUCTURE KW - DATA ACQUISITION KW - DATA INTERPRETATION KW - SW 0880:Chemical processes KW - SW 5080:Evaluation, processing and publication KW - SW 3010:Identification of pollutants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19070112?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=CONVERSATIONAL+MASS+SPECTRAL+RETRIEVAL+SYSTEM+AND+ITS+USE+AS+AN+AID+IN+STRUCTURE+DETERMINATION&rft.au=Heller&rft.aulast=Heller&rft.aufirst=&rft.date=1951-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - THE SLOW RECOVERY OF BACTERIA FROM THE TOXIC EFFECTS OF PENICILLIN. AN - 74538281; 16561809 JF - Journal of bacteriology AU - Eagle, H AU - Musselman, A D AD - Section on Experimental Therapeutics, National Institutes of Health, U. S. Public Health Service, Bethesda 14, Maryland. Y1 - 1949/10// PY - 1949 DA - October 1949 SP - 475 EP - 490 VL - 58 IS - 4 SN - 0021-9193, 0021-9193 KW - Penicillins KW - 0 KW - Old Medline KW - PENICILLIN/effects KW - Penicillins -- pharmacology KW - Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/74538281?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+bacteriology&rft.atitle=THE+SLOW+RECOVERY+OF+BACTERIA+FROM+THE+TOXIC+EFFECTS+OF+PENICILLIN.&rft.au=Eagle%2C+H%3BMusselman%2C+A+D&rft.aulast=Eagle&rft.aufirst=H&rft.date=1949-10-01&rft.volume=58&rft.issue=4&rft.spage=475&rft.isbn=&rft.btitle=&rft.title=Journal+of+bacteriology&rft.issn=00219193&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-05-25 N1 - Date created - 2006-05-25 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Bacteriol. 1946 Feb;51(2):181-6 [16561067] J Bacteriol. 1948 Jul;56(1):75-81 [16561549] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - THE RECOVERY OF BACTERIA FROM THE TOXIC EFFECTS OF PENICILLIN. AN - 74530920; 16695745 JF - The Journal of clinical investigation AU - Eagle, H AD - Section on Experimental Therapeutics, National Institutes of Health, U. S. Public Health Service, Bethesda 14, Maryland. Y1 - 1949/09// PY - 1949 DA - September 1949 SP - 832 EP - 836 VL - 28 IS - 5 Pt 1 SN - 0021-9738, 0021-9738 KW - Penicillins KW - 0 KW - Old Medline KW - PENICILLIN/toxicity KW - Bacteria KW - Penicillins -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/74530920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+clinical+investigation&rft.atitle=THE+RECOVERY+OF+BACTERIA+FROM+THE+TOXIC+EFFECTS+OF+PENICILLIN.&rft.au=Eagle%2C+H&rft.aulast=Eagle&rft.aufirst=H&rft.date=1949-09-01&rft.volume=28&rft.issue=5+Pt+1&rft.spage=832&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+clinical+investigation&rft.issn=00219738&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-05-31 N1 - Date created - 2006-05-31 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Bacteriol. 1946 Feb;51(2):181-6 [16561067] N1 - Last updated - 2017-01-18 ER -