TY - JOUR T1 - Estimated Variability of National Atmospheric Deposition Program/Mercury Deposition Network Measurements Using Collocated Samplers AN - 745936872; 13167478 AB - The National Atmospheric Deposition Program/Mercury Deposition Network (MDN) provides long-term, quality-assured records of mercury in wet deposition in the USA and Canada. Interpretation of spatial and temporal trends in the MDN data requires quantification of the variability of the MDN measurements. Variability is quantified for MDN data from collocated samplers at MDN sites in two states, one in Illinois and one in Washington. Median absolute differences in the collocated sampler data for total mercury concentration are approximately 11% of the median mercury concentration for all valid 1999-2004 MDN data. Median absolute differences are between 3.0% and 14% of the median MDN value for collector catch (sample volume) and between 6.0% and 15% of the median MDN value for mercury wet deposition. The overall measurement errors are sufficiently low to resolve between NADP/MDN measurements by c2ng.l super(-1) and c2kg.m super(-2).year super(-1), which are the contour intervals used to display the data on NADP isopleths maps for concentration and deposition, respectively. JF - Environmental Monitoring and Assessment AU - Wetherbee, Gregory A AU - Gay, David A AU - Brunette, Robert C AU - Sweet, Clyde W AD - US Geological Survey, Water Resources Discipline, Office of Water Quality, Branch of Quality Systems, Box 25046, MS 401, Denver Federal Center, Denver, CO, 80225, USA Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 49 EP - 69 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 131 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Toxicology Abstracts; Pollution Abstracts; Environment Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Meteorological & Geoastrophysical Abstracts KW - Maps KW - USA, Washington KW - Isopleths KW - Mercury in the atmosphere KW - Environmental monitoring KW - Atmospheric precipitations KW - catches KW - Atmospheric pollution KW - Data processing KW - USA, Illinois KW - Atmospheric variability KW - Wet deposition KW - Samplers KW - NADP KW - Pollutant deposition KW - Mercury deposition KW - Canada KW - Mercury KW - Q5 08503:Characteristics, behavior and fate KW - P 2000:FRESHWATER POLLUTION KW - M2 551.5:General (551.5) KW - X 24360:Metals KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745936872?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=Estimated+Variability+of+National+Atmospheric+Deposition+Program%2FMercury+Deposition+Network+Measurements+Using+Collocated+Samplers&rft.au=Wetherbee%2C+Gregory+A%3BGay%2C+David+A%3BBrunette%2C+Robert+C%3BSweet%2C+Clyde+W&rft.aulast=Wetherbee&rft.aufirst=Gregory&rft.date=2007-08-01&rft.volume=131&rft.issue=1-3&rft.spage=49&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-006-9456-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Atmospheric precipitations; Environmental monitoring; Mercury; Isopleths; Samplers; Data processing; Maps; NADP; Mercury in the atmosphere; Mercury deposition; Atmospheric pollution; Atmospheric variability; Wet deposition; catches; Pollutant deposition; USA, Washington; Canada; USA, Illinois DO - http://dx.doi.org/10.1007/s10661-006-9456-6 ER - TY - JOUR T1 - Transcriptional profiling of mucociliary differentiation in human airway epithelial cells. AN - 70717673; 17413031 AB - When cultured at an air-liquid interface (ALI) in the appropriate medium, primary human airway epithelial cells form a polarized, pseudostratified epithelium composed of ciliated and mucus-secreting cells. This culture system provides a useful tool for the in vitro study of airway epithelial biology and differentiation. We have performed microarray analysis on ALI cultures of human bronchial epithelial cells (HBECs) grown over a 28-d period to identify genes involved in mucociliary differentiation. We identified over 2,000 genes that displayed statistically significant 2-fold or greater changes in expression during the time course. Of the genes showing the largest increases, many are involved in processes associated with airway epithelial biology, such as cell adhesion, immunity, transport, and cilia formation; however, many novel genes were also identified. We compared our results with data from proteomic analyses of the ciliary axoneme and identified candidate genes that may have roles in cilia formation or function. Gene networks were generated using Ingenuity Pathways Analysis (Ingenuity Systems, Redwood City, CA) to identify signaling pathways involved in mucociliary cell differentiation or function. Networks containing genes involved in TGF-beta, WNT/beta-catenin, and epidermal growth factor receptor (EGFR) pathways were identified, suggesting potential roles for these families in airway epithelia. Microarray results were validated by real-time RT-PCR for a number of representative genes. This work has provided extensive information about gene expression changes during differentiation of airway epithelial cells, and will be a useful resource for researchers interested in respiratory function, pathology, and toxicology. JF - American journal of respiratory cell and molecular biology AU - Ross, Andrea J AU - Dailey, Lisa A AU - Brighton, Luisa E AU - Devlin, Robert B AD - Clinical Research Branch, Human Studies Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, University of North Carolina, Chapel Hill, North Carolina 27599-7315, USA. Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 169 EP - 185 VL - 37 IS - 2 SN - 1044-1549, 1044-1549 KW - Mucins KW - 0 KW - Index Medicus KW - Gene Expression Profiling KW - Epithelial Cells -- physiology KW - Epithelial Cells -- cytology KW - Oligonucleotide Array Sequence Analysis KW - Mucins -- genetics KW - Cell Polarity KW - Mucins -- metabolism KW - Cells, Cultured KW - Humans KW - Gene Regulatory Networks KW - Molecular Sequence Data KW - Cell Culture Techniques KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Respiratory Mucosa -- cytology KW - Cell Differentiation -- physiology KW - Cilia -- physiology KW - Cilia -- metabolism KW - Cell Differentiation -- genetics KW - Transcription, Genetic UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70717673?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+respiratory+cell+and+molecular+biology&rft.atitle=Transcriptional+profiling+of+mucociliary+differentiation+in+human+airway+epithelial+cells.&rft.au=Ross%2C+Andrea+J%3BDailey%2C+Lisa+A%3BBrighton%2C+Luisa+E%3BDevlin%2C+Robert+B&rft.aulast=Ross&rft.aufirst=Andrea&rft.date=2007-08-01&rft.volume=37&rft.issue=2&rft.spage=169&rft.isbn=&rft.btitle=&rft.title=American+journal+of+respiratory+cell+and+molecular+biology&rft.issn=10441549&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-17 N1 - Date created - 2007-07-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Varying stable nitrogen isotope ratios of different coastal marsh plants and their relationships with wastewater nitrogen and land use in New England, USA. AN - 70649678; 17171277 AB - The stable nitrogen isotope ratios of some biota have been used as indicators of sources of anthropogenic nitrogen. In this study the relationships of the stable nitrogen isotope ratios of marsh plants, Iva frutescens (L.), Phragmites australis (Cav.) Trin ex Steud, Spartina patens (Ait.) Muhl, Spartina alterniflora Loisel, Ulva lactuca (L.), and Enteromorpha intestinalis (L.) with wastewater nitrogen and land development in New England are described. Five of the six plant species (all but U. lactuca) showed significant relationships of increasing delta (15)N values with increasing wastewater nitrogen. There was a significant (P < 0.0001) downward shift in the delta (15)N of S. patens (6.0 +/- 0.48 per thousand) which is mycorrhizal compared with S. alterniflora (8.5 +/- 0.41 per thousand). The downward shift in delta (15)N may be caused by the assimilation of fixed nitrogen in the roots of S. patens. P. australis within sites had wide ranges of delta (15)N values, evidently influenced by the type of shoreline development or buffer at the upland border. In residential areas, the presence of a vegetated buffer (n = 24 locations) significantly (P < 0.001) reduced the delta (15)N (mean = 7.4 +/- 0.43 per thousand) of the P. australis compared to stands where there was no buffer (mean = 10.9 +/- 1.0 per thousand; n = 15). Among the plant species, I. frutescens located near the upland border showed the most significant (R (2) = 0.64; P = 0.006) inverse relationship with the percent agricultural land in the watershed. The delta (15)N of P. australis and I. frustescens is apparently an indicator of local inputs near the upland border, while the delta (15)N of Spartina relates with the integrated, watershed-sea nitrogen inputs. JF - Environmental monitoring and assessment AU - Wigand, Cathleen AU - McKinney, Richard A AU - Cole, Marci L AU - Thursby, Glen B AU - Cummings, Jean AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Atlantic Ecology Division, US EPA, 27 Tarzwell Drive, Narragansett, RI, 02882, USA. wigand.cathleen@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 71 EP - 81 VL - 131 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Nitrogen Isotopes KW - 0 KW - Sewage KW - Index Medicus KW - Ecosystem KW - New England KW - Plants -- chemistry KW - Nitrogen Isotopes -- analysis KW - Wetlands KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70649678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+monitoring+and+assessment&rft.atitle=Varying+stable+nitrogen+isotope+ratios+of+different+coastal+marsh+plants+and+their+relationships+with+wastewater+nitrogen+and+land+use+in+New+England%2C+USA.&rft.au=Wigand%2C+Cathleen%3BMcKinney%2C+Richard+A%3BCole%2C+Marci+L%3BThursby%2C+Glen+B%3BCummings%2C+Jean&rft.aulast=Wigand&rft.aufirst=Cathleen&rft.date=2007-08-01&rft.volume=131&rft.issue=1-3&rft.spage=71&rft.isbn=&rft.btitle=&rft.title=Environmental+monitoring+and+assessment&rft.issn=01676369&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-20 N1 - Date created - 2007-06-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Perfluorinated compounds in the Cape Fear Drainage Basin in North Carolina. AN - 68244462; 17822090 AB - Concern over perfluorinated organic compounds (PFCs), e.g., perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), is due to a number of recent studies which show that the PFCs are persistent, bioaccumulative, and toxic in animals. Despite sustained interest in this topic, little information is available concerning the environmental distributions of the compounds. In this study, a new method was developed for the analysis of 10 target PFCs and its performance was examined in a systematic evaluation of surface water in the Cape Fear River Basin in North Carolina. One hundred samples from 80 different locations were collected during the spring of 2006. Detectable levels of the target PFCs were found in all samples, and were comparable to values reported previously, with maximum PFOS at 132 ng/L, PFOA at 287 ng/L, perfluorononanoic acid (C9) at 194 ng/L, and perfluoroheptanoic acid (C7) at 329 ng/L. In general, the lowest concentrations of the PFCs were found in the smallest tributaries while the highest levels were found in middle reaches of the Drainage Basin. Variability of PFC concentrations suggests a series of source inputs throughout the Basin. Seventeen sample sites (22%) had PFOS concentrations greater than 43 ng/L, a conservative safe water concentration estimated to be protective of avian life. In addition, a total of 26 sites (32%) had PFOA concentrations above 40 ng/L. JF - Environmental science & technology AU - Nakayama, Shoji AU - Strynar, Mark J AU - Helfant, Laurence AU - Egeghy, Peter AU - Ye, Xibiao AU - Lindstrom, Andrew B AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 SP - 5271 EP - 5276 VL - 41 IS - 15 SN - 0013-936X, 0013-936X KW - Alkanesulfonic Acids KW - 0 KW - Caprylates KW - Fluorocarbons KW - perfluorooctanoic acid KW - 947VD76D3L KW - perfluorooctane sulfonic acid KW - 9H2MAI21CL KW - Index Medicus KW - Animals KW - Reproducibility of Results KW - North Carolina KW - Environmental Exposure KW - Geography KW - Fluorocarbons -- analysis KW - Alkanesulfonic Acids -- analysis KW - Caprylates -- analysis KW - Rivers -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68244462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Perfluorinated+compounds+in+the+Cape+Fear+Drainage+Basin+in+North+Carolina.&rft.au=Nakayama%2C+Shoji%3BStrynar%2C+Mark+J%3BHelfant%2C+Laurence%3BEgeghy%2C+Peter%3BYe%2C+Xibiao%3BLindstrom%2C+Andrew+B&rft.aulast=Nakayama&rft.aufirst=Shoji&rft.date=2007-08-01&rft.volume=41&rft.issue=15&rft.spage=5271&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-11-29 N1 - Date created - 2007-09-07 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Environ Sci Technol. 2008 Feb 15;42(4):1385-6 [18351121] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Aquatic invertebrate resting egg sensitivity to glutaraldehyde and sodium hypochlorite. AN - 68174985; 17702354 AB - Ballast tank treatment technologies are currently in development to reduce the risk of acquiring or transporting viable aquatic organisms that could be introduced to ecosystems and become invasive. Aquatic invertebrate resting eggs represent a challenge to such technologies because of morphological and biochemical adaptations to stress that also protect eggs from artificial stressors. To evaluate the potential efficacy of chemical biocides for ballast tank treatment, the present study examined the acute toxicity of glutaraldehyde and sodium hypochlorite on resting eggs of the freshwater cladoceran Daphnia mendotae and marine brine shrimp (Artemia sp.). Glutaraldehyde was toxic to resting eggs of Artemia sp., as indicated by a lethal concentration to 90% of organisms (LC90) of 95% confidence interval (226 +/- 10 mg/L). Daphnia mendotae, in contrast, displayed erratic responses to glutaraldehyde. Sodium hypochlorite was similarly toxic to resting eggs of Artemia sp. and D. mendotae, which displayed LC90s of 86.5 +/- 3.0 and 78.3 +/- 1.6 mg/L, respectively. Burial in sediment protected resting eggs from toxicants. The present results corroborate those from previous investigations of resting egg sensitivity to artificial stressors, supporting the conclusions that resting eggs are less sensitive than other life stages to artificial stressors and that chemical biocide concentrations effective against other life stages may be ineffective against resting stages. JF - Environmental toxicology and chemistry AU - Raikow, David E AU - Landrum, Peter E AU - Reid, David E AD - National Oceanic and Atmospheric Administration, National Center for Research on Aquatic Invasive Species, 2205 Commonwealth Boulevard, Ann Arbor, Michigan 48105, USA. raikow.david@epamail.epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 1770 EP - 1773 VL - 26 IS - 8 SN - 0730-7268, 0730-7268 KW - Disinfectants KW - 0 KW - Water Pollutants, Chemical KW - Sodium Hypochlorite KW - DY38VHM5OD KW - Glutaral KW - T3C89M417N KW - Index Medicus KW - Geologic Sediments -- chemistry KW - Animals KW - Fresh Water -- chemistry KW - Dose-Response Relationship, Drug KW - Glutaral -- metabolism KW - Invertebrates -- drug effects KW - Sodium Hypochlorite -- metabolism KW - Water Pollutants, Chemical -- toxicity KW - Sodium Hypochlorite -- toxicity KW - Invertebrates -- growth & development KW - Eggs -- analysis KW - Disinfectants -- metabolism KW - Glutaral -- toxicity KW - Disinfectants -- toxicity KW - Water Pollutants, Chemical -- metabolism KW - Eggs -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68174985?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Aquatic+invertebrate+resting+egg+sensitivity+to+glutaraldehyde+and+sodium+hypochlorite.&rft.au=Raikow%2C+David+E%3BLandrum%2C+Peter+E%3BReid%2C+David+E&rft.aulast=Raikow&rft.aufirst=David&rft.date=2007-08-01&rft.volume=26&rft.issue=8&rft.spage=1770&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-03 N1 - Date created - 2007-08-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Intersex in Japanese medaka (Oryzias latipes) used as negative controls in toxicologic bioassays: a review of 54 cases from 41 studies. AN - 68173885; 17702336 AB - Histologic assessment of the gonads to detect intersex has become a valuable end point in reproductive toxicologic testing for fish, and many studies have solidly linked intersex with exposure to endocrine active substances (EAS). An assumption in such studies is that spontaneous intersex does not occur in control fish. Using historical data derived from toxicologic tests with Japanese medaka (Oryzias latipes), we report a retrospective study in which we identified 54 individual instances of intersex (testicular oocytes or ovarian testicular tissue) in control medaka from 15 of 41 selected toxicologic studies. These studies, comprised of previously unpublished data, had been conducted at three geographically distant laboratories, each of which utilized unique water sources, employed somewhat different culture protocols, and maintained distinct medaka breeding colonies. During our histologic examinations, we also identified three germ cell neoplasms that had been inadvertently diagnosed as intersex. In the present report, we review potential causes of intersex, discuss possible reasons why spontaneous intersex has rarely been reported, and propose suggestions for the judicious interpretation of intersex results in medaka studies involving EAS. JF - Environmental toxicology and chemistry AU - Grim, K Christiana AU - Wolfe, Marilyn AU - Hawkins, William AU - Johnson, Rodney AU - Wolf, Jeffrey AD - U.S. Environmental Protection Agency, Office of Science Coordination and Policy, 1201 Constitution Avenue, Northwest, EPA East Building 4121M, Washington, DC 20004, USA. Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 1636 EP - 1643 VL - 26 IS - 8 SN - 0730-7268, 0730-7268 KW - Endocrine Disruptors KW - 0 KW - Water Pollutants, Chemical KW - Index Medicus KW - Animals KW - Toxicity Tests KW - Neoplasms, Germ Cell and Embryonal -- pathology KW - Geography KW - Male KW - Female KW - Sexual Behavior, Animal -- drug effects KW - Oryzias KW - Endocrine Disruptors -- toxicity KW - Testis -- physiology KW - Testis -- drug effects KW - Ovary -- pathology KW - Water Pollutants, Chemical -- toxicity KW - Testis -- pathology KW - Ovary -- drug effects KW - Biological Assay KW - Ovary -- physiology KW - Sexual Behavior, Animal -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68173885?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Intersex+in+Japanese+medaka+%28Oryzias+latipes%29+used+as+negative+controls+in+toxicologic+bioassays%3A+a+review+of+54+cases+from+41+studies.&rft.au=Grim%2C+K+Christiana%3BWolfe%2C+Marilyn%3BHawkins%2C+William%3BJohnson%2C+Rodney%3BWolf%2C+Jeffrey&rft.aulast=Grim&rft.aufirst=K&rft.date=2007-08-01&rft.volume=26&rft.issue=8&rft.spage=1636&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-03 N1 - Date created - 2007-08-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The healthy men study: an evaluation of exposure to disinfection by-products in tap water and sperm quality. AN - 68142627; 17687443 AB - Chlorination of drinking water generates disinfection by-products (DBPs), which have been shown to disrupt spermatogenesis in rodents at high doses, suggesting that DBPs could pose a reproductive risk to men. In this study we assessed DBP exposure and testicular toxicity, as evidenced by altered semen quality. We conducted a cohort study to evaluate semen quality in men with well-characterized exposures to DBPs. Participants were 228 presumed fertile men with different DBP profiles. They completed a telephone interview about demographics, health history, water consumption, and other exposures and provided a semen sample. Semen outcomes included sperm concentration and morphology, as well as DNA integrity and chromatin maturity. Exposures to DBPs were evaluated by incorporating data on water consumption and bathing and showering with concentrations measured in tap water. We used multivariable linear regression to assess the relationship between exposure to DBPs and adverse sperm outcomes. The mean (median) sperm concentration and sperm count were 114.2 (90.5) million/mL and 362 (265) million, respectively. The mean (median) of the four trihalomethane species (THM4) exposure was 45.7 (65.3) microg/L, and the mean (median) of the nine haloacetic acid species (HAA9) exposure was 30.7 (44.2) microg/L. These sperm parameters were not associated with exposure to these classes of DBPs. For other sperm outcomes, we found no consistent pattern of increased abnormal semen quality with elevated exposure to trihalomethanes (THMs) or haloacetic acids (HAAs). The use of alternate methods for assessing exposure to DBPs and site-specific analyses did not change these results. The results of this study do not support an association between exposure to levels of DBPs near or below regulatory limits and adverse sperm outcomes in humans. JF - Environmental health perspectives AU - Luben, Thomas J AU - Olshan, Andrew F AU - Herring, Amy H AU - Jeffay, Susan AU - Strader, Lillian AU - Buus, Rebecca M AU - Chan, Ronna L AU - Savitz, David A AU - Singer, Philip C AU - Weinberg, Howard S AU - Perreault, Sally D AD - Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, NC, USA. luben.tom@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 1169 EP - 1176 VL - 115 IS - 8 SN - 0091-6765, 0091-6765 KW - Acetates KW - 0 KW - Disinfectants KW - Trihalomethanes KW - Water Pollutants, Chemical KW - Chlorine KW - 4R7X1O2820 KW - Index Medicus KW - Disinfection KW - Acetates -- analysis KW - Sperm Count KW - Humans KW - Disinfectants -- chemistry KW - Adult KW - Trihalomethanes -- toxicity KW - Water Purification KW - Chlorine -- chemistry KW - Acetates -- toxicity KW - Trihalomethanes -- analysis KW - Male KW - Water Supply -- analysis KW - Water Pollutants, Chemical -- analysis KW - Spermatozoa -- cytology KW - Water Pollutants, Chemical -- toxicity KW - Spermatozoa -- drug effects KW - Environmental Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68142627?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=The+healthy+men+study%3A+an+evaluation+of+exposure+to+disinfection+by-products+in+tap+water+and+sperm+quality.&rft.au=Luben%2C+Thomas+J%3BOlshan%2C+Andrew+F%3BHerring%2C+Amy+H%3BJeffay%2C+Susan%3BStrader%2C+Lillian%3BBuus%2C+Rebecca+M%3BChan%2C+Ronna+L%3BSavitz%2C+David+A%3BSinger%2C+Philip+C%3BWeinberg%2C+Howard+S%3BPerreault%2C+Sally+D&rft.aulast=Luben&rft.aufirst=Thomas&rft.date=2007-08-01&rft.volume=115&rft.issue=8&rft.spage=1169&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-02 N1 - Date created - 2007-08-09 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Androl. 2000 May-Jun;21(3):478-84 [10819457] Am J Epidemiol. 2006 Dec 1;164(11):1043-51 [16957027] J Assist Reprod Genet. 2000 Oct;17(9):508-14 [11155324] Methods Cell Sci. 2000;22(2-3):169-89 [11264952] J Hazard Mater. 2007 Mar 6;141(1):289-94 [16916574] Fertil Steril. 2007 Mar;87(3):554-64 [17140573] J Androl. 2002 Jan-Feb;23(1):25-43 [11780920] Int J Toxicol. 2002 Jul-Aug;21(4):237-76 [12171628] Occup Environ Med. 2003 Mar;60(3):173-80 [12598663] Epidemiology. 2003 Nov;14(6):650-8 [14569179] Reprod Toxicol. 2004 Nov;19(1):111-6 [15336719] Toxicol Sci. 2004 Oct;81(2):430-42 [15254336] Biol Reprod. 1993 Nov;49(5):1083-8 [8286574] Fundam Appl Toxicol. 1994 Apr;22(3):422-30 [8050637] Reprod Toxicol. 1994 May-Jun;8(3):251-9 [8075514] Biol Reprod. 1995 May;52(5):1149-55 [7626715] Environ Health Perspect. 1995 Jun;103(6):592-6 [7556013] Fundam Appl Toxicol. 1995 Nov;28(1):9-17 [8566488] J Androl. 1996 May-Jun;17(3):288-92 [8792219] Reprod Toxicol. 1997 Jan-Feb;11(1):47-56 [9138633] Reprod Toxicol. 1997 Sep-Oct;11(5):681-8 [9311576] Epidemiology. 1998 Mar;9(2):134-40 [9504280] Epidemiology. 1999 Jul;10(4):383-90 [10401872] Am J Anat. 1963 Jan;112:35-51 [14021715] Recent Prog Horm Res. 1964;20:545-75 [14285045] Environ Health Perspect. 2005 Feb;113(2):225-32 [15687062] Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9601-6 [16766665] J Toxicol Environ Health A. 2006 Dec;69(23):2095-136 [17060096] Anim Reprod Sci. 2000 Jul 2;60-61:121-30 [10844189] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Analytic element ground water modeling as a research program (1980 to 2006) AN - 51373631; 2007-107216 JF - Ground Water AU - Kraemer, Stephen R Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 402 EP - 408 PB - National Ground Water Association, Westerville, OH VL - 45 IS - 4 SN - 0017-467X, 0017-467X KW - analytic element method KW - programs KW - numerical models KW - engineering properties KW - finite difference analysis KW - philosophy KW - mathematical models KW - hydrogeology KW - preferential flow KW - research KW - reservoir rocks KW - ground water KW - models KW - history KW - finite element analysis KW - physical properties KW - theoretical models KW - hydrodynamics KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51373631?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nature+Biotechnology&rft.atitle=A+framework+for+the+use+of+genomics+data+at+the+EPA&rft.au=Dix%2C+D+J%3BGallagher%2C+K%3BBenson%2C+W+H%3BGrokinsky%2C+B+L%3BMcClintock%2C+J+T%3BDearfield%2C+K+L%3BFarland%2C+W+H&rft.aulast=Dix&rft.aufirst=D&rft.date=2006-09-01&rft.volume=24&rft.issue=9&rft.spage=1108&rft.isbn=&rft.btitle=&rft.title=Nature+Biotechnology&rft.issn=10870156&rft_id=info:doi/10.1038%2Fnbt0906-1108 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2016, American Geosciences Institute. N1 - Date revised - 2007-01-01 N1 - Number of references - 38 N1 - PubXState - OH N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2016-11-17 N1 - CODEN - GRWAAP N1 - SubjectsTermNotLitGenreText - analytic element method; engineering properties; finite difference analysis; finite element analysis; ground water; history; hydrodynamics; hydrogeology; mathematical models; models; numerical models; philosophy; physical properties; preferential flow; programs; research; reservoir rocks; theoretical models DO - http://dx.doi.org/10.1111/j.1745-6584.2007.00314.x ER - TY - JOUR T1 - High arsenic concentrations and enriched sulfur and oxygen isotopes in a fractured bedrock-ground water system AN - 51244655; 2008-016693 AB - Ground water with high arsenic concentrations (up to 26.6 mu mmol L (super -1) ) has sulfate enriched in (super 34) S and (super 18) O in the fractured-bedrock, ground-water system of the Kelly's Cove watershed, Northport, Maine, USA. The ranges of sulfur and oxygen isotope values in aqueous sulfate, delta (super 34) S (sub [SO4]) and delta (super 18) O (sub [SO4]) , at the Kelly's Cove watershed are +3.4 to +4.9ppm and -2.0 to +6.7ppm, respectively. These isotope values are strikingly similar to those of the Goose River, Maine watershed which has delta (super 34) S (sub [SO4]) and delta (super 18) O (sub [SO4]) ranges of +3.7 to +4.6 ppm and -2.6 to +7.5ppm, respectively. In both systems, high arsenic concentrations occur with high delta (super 34) S (sub [SO4]) and delta (super 18) O (sub [SO4]) values, yet redox conditions and underlying rock types are quite different. The isotope values of sulfide minerals, delta (super 34) S (sub [min]) , from four bedrock cores vary over short distances and range from -5.1 to +7.5ppm. The delta (super 34) S (sub [SO4]) values are controlled by the delta (super 34) S (sub [min]) values with minor input of atmospheric SO (sub 4) . The much narrower range in delta (super 34) S (sub [SO4]) values than delta (super 34) S (sub [min]) values is probably due to sufficient ground-water mixing at a scale greater than the delta (super 34) S (sub [min]) variability. The delta (super 34) S (sub [SO4]) values are about 2ppm higher than the average delta (super 34) S (sub [min]) value and fall within the range of delta (super 34) S (sub [min]) values, indicating only minor fractionation due to bacterial reduction of SO (sub 4) . The highest delta (super 18) O (sub [SO4]) values were measured in the downgradient, confined, arsenic-rich ground water. High delta (super 18) O (sub [SO4]) values there cannot be due to aeration by atmospheric oxygen, but may arise from reoxidation of reduced SO (sub 4) products. The enrichment factors of delta (super 18) O in SO (sub 4) compared to H (sub 2) O, +7.2 to +15.5ppm, in the Kelly's Cove ground water and the negligible (super 34) S enrichment is very similar to those derived from experimental data of anaerobic sulfide oxidation in the presence of Mn and Fe oxides. Sea level at the Kelly's Cove watershed was approximately 80 m above present sea level about 13000 years before present, imposing reducing conditions on that area of the watershed. Sea level dropped approximately 60 m below present sea level about 11000 years before present, allowing for possible oxidation of sulfide minerals and precipitation of arsenic in ferric oxyhydroxides during aeration of the ground-water system. Under present redox conditions, there is evidence that bacteria reduction of ferric oxyhydroxides releases arsenic. The fractionation of (super 18) O in the SO (sub 4) during anaerobic oxidation of sulfide in the presence of Mn and Fe oxides and subsequent release of arsenic during Mn and Fe oxide reduction may explain the relationship between high arsenic concentrations and elevated (super 18) O (sub [SO4]) at Kelly's Cove. JF - Chemical Geology AU - Lipfert, Gail AU - Sidle, William C AU - Reeve, Andrew S AU - Ayuso, Robert A AU - Boyce, Adrian J Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 385 EP - 399 PB - Elsevier, Amsterdam VL - 242 IS - 3-4 SN - 0009-2541, 0009-2541 KW - United States KW - oxygen KW - isotopes KW - Lincoln County Maine KW - enrichment KW - stable isotopes KW - ground water KW - chemical reactions KW - water-rock interaction KW - drainage basins KW - chemical composition KW - water pollution KW - geochemistry KW - Northport Maine KW - sulfates KW - pollutants KW - isotope ratios KW - oxidation KW - statistical analysis KW - Kelly's Cove KW - arsenic KW - pollution KW - O-18/O-16 KW - hydrochemistry KW - Waldo County Maine KW - S-34/S-32 KW - metals KW - naturally fractured reservoirs KW - sulfur KW - anaerobic environment KW - Maine KW - histograms KW - 02D:Isotope geochemistry KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51244655?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemical+Geology&rft.atitle=High+arsenic+concentrations+and+enriched+sulfur+and+oxygen+isotopes+in+a+fractured+bedrock-ground+water+system&rft.au=Lipfert%2C+Gail%3BSidle%2C+William+C%3BReeve%2C+Andrew+S%3BAyuso%2C+Robert+A%3BBoyce%2C+Adrian+J&rft.aulast=Lipfert&rft.aufirst=Gail&rft.date=2007-08-01&rft.volume=242&rft.issue=3-4&rft.spage=385&rft.isbn=&rft.btitle=&rft.title=Chemical+Geology&rft.issn=00092541&rft_id=info:doi/10.1016%2Fj.chemgeo.2007.04.003 L2 - http://www.sciencedirect.com/science/journal/00092541 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2008-01-01 N1 - Number of references - 53 N1 - Document feature - illus. incl. 3 tables, sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - CHGEAD N1 - SubjectsTermNotLitGenreText - anaerobic environment; arsenic; chemical composition; chemical reactions; drainage basins; enrichment; geochemistry; ground water; histograms; hydrochemistry; isotope ratios; isotopes; Kelly's Cove; Lincoln County Maine; Maine; metals; naturally fractured reservoirs; Northport Maine; O-18/O-16; oxidation; oxygen; pollutants; pollution; S-34/S-32; stable isotopes; statistical analysis; sulfates; sulfur; United States; Waldo County Maine; water pollution; water-rock interaction DO - http://dx.doi.org/10.1016/j.chemgeo.2007.04.003 ER - TY - JOUR T1 - In situ chemical reduction of Cr(VI) in ground water using a combination of ferrous sulfate and sodium dithionite; a field investigation AN - 51010184; 2008-090512 JF - Environmental Science & Technology, ES & T AU - Ludwig, Ralph D AU - Su, Chunming AU - Lee, Tony R AU - Wilkin, Richard T AU - Acree, Steven D AU - Ross, Randall R AU - Keeley, Ann Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 SP - 5299 EP - 5305 PB - American Chemical Society, Washington, DC VL - 41 IS - 15 SN - 0013-936X, 0013-936X KW - contaminant plumes KW - mass spectra KW - citrate-bicarbonate-dithionite method KW - iron KW - remediation KW - ground water KW - chemical reactions KW - movement KW - spectra KW - reduction KW - chemical composition KW - water pollution KW - geochemistry KW - chromium KW - in situ KW - sulfates KW - pollutants KW - solutes KW - pollution KW - adsorption KW - hydrochemistry KW - depth KW - ferrous iron KW - aquifers KW - solid phase KW - ICP mass spectra KW - precipitation KW - metals KW - hydraulic conductivity KW - SEM data KW - field studies KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51010184?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology%2C+ES+%26+T&rft.atitle=In+situ+chemical+reduction+of+Cr%28VI%29+in+ground+water+using+a+combination+of+ferrous+sulfate+and+sodium+dithionite%3B+a+field+investigation&rft.au=Ludwig%2C+Ralph+D%3BSu%2C+Chunming%3BLee%2C+Tony+R%3BWilkin%2C+Richard+T%3BAcree%2C+Steven+D%3BRoss%2C+Randall+R%3BKeeley%2C+Ann&rft.aulast=Ludwig&rft.aufirst=Ralph&rft.date=2007-08-01&rft.volume=41&rft.issue=15&rft.spage=5299&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology%2C+ES+%26+T&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes070025z L2 - http://pubs.acs.org/journals/esthag/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 39 N1 - PubXState - DC N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2014-03-14 N1 - CODEN - ESTHAG N1 - SubjectsTermNotLitGenreText - adsorption; aquifers; chemical composition; chemical reactions; chromium; citrate-bicarbonate-dithionite method; contaminant plumes; depth; ferrous iron; field studies; geochemistry; ground water; hydraulic conductivity; hydrochemistry; ICP mass spectra; in situ; iron; mass spectra; metals; movement; pollutants; pollution; precipitation; reduction; remediation; SEM data; solid phase; solutes; spectra; sulfates; water pollution DO - http://dx.doi.org/10.1021/es070025z ER - TY - CPAPER T1 - Control the BestProtect the Rest: An Innovative Approach to Moving from Assessment to Implementation. T2 - 10th Annual Southeast Watershed Roundtable AN - 39593450; 4724131 DE: JF - 10th Annual Southeast Watershed Roundtable AU - Young, K R Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39593450?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=10th+Annual+Southeast+Watershed+Roundtable&rft.atitle=Control+the+BestProtect+the+Rest%3A+An+Innovative+Approach+to+Moving+from+Assessment+to+Implementation.&rft.au=Young%2C+K+R&rft.aulast=Young&rft.aufirst=K&rft.date=2007-08-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=10th+Annual+Southeast+Watershed+Roundtable&rft.issn=&rft_id=info:doi/ L2 - http://www.southeastwaterforum.org/roundtables/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Protecting Water Quality and Mitigating Floods through Land Conservation: Examples from GA, NC and TX. T2 - 10th Annual Southeast Watershed Roundtable AN - 39588766; 4724129 JF - 10th Annual Southeast Watershed Roundtable AU - Pawlukiewicz, Janet Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 KW - Conservation KW - Water quality KW - Floods KW - Mitigation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39588766?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=10th+Annual+Southeast+Watershed+Roundtable&rft.atitle=Protecting+Water+Quality+and+Mitigating+Floods+through+Land+Conservation%3A+Examples+from+GA%2C+NC+and+TX.&rft.au=Pawlukiewicz%2C+Janet&rft.aulast=Pawlukiewicz&rft.aufirst=Janet&rft.date=2007-08-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=10th+Annual+Southeast+Watershed+Roundtable&rft.issn=&rft_id=info:doi/ L2 - http://www.southeastwaterforum.org/roundtables/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - A comparison of CMAQ-based aerosol properties with IMPROVE, MODIS, and AERONET data AN - 21040660; 7579668 AB - Evaluation of concentrations predicted by air quality models is needed to ensure that model results are compatible with observations. In this study aerosol properties derived from the Community Multiscale Air Quality (CMAQ) model-simulated aerosol mass concentrations are compared with routine data from NASA satellite-borne Moderate Resolution Imaging Spectroradiometer (MODIS) sensor aboard the Sun-synchronous Terra satellite, NASAs ground-based Aerosol Robotic Network (AERONET), and the ground-based Interagency Monitoring of Protected Visual Environment (IMPROVE) network. The motivation for this analysis is to determine how best to use these parameters in evaluating model-predicted PM sub(2.5) concentrations. CMAQ surface extinction estimates due to scattering at 550 nm wavelength are compared with the IMPROVE nephelometer data obtained from 25 sites within the United States. It is found that model-predicted surface extinctions bear high correlations with nephelometer measured data. Sulfate fractional aerosol optical depth (AOD) is found to dominate in the northeastern part of the United States; hence ground-based measurement of sulfate concentrations have been compared with time series of columnar AOD as observed by the MODIS instrument and also with the CMAQ-predicted tropospheric column values obtained during the June-August period of 2001. CMAQ surface extinctions are found to be relatively higher than the IMPROVE nephelometer observations; however, there is a good agreement between CMAQ AOD trends and AERONET and MODIS data, obtained at the seven AERONET sites located in the eastern United States. CMAQ is also found to capture the day-to-day variability in the spatial AOD patterns. Monthly average satellite AOD estimates are found to be higher than the AOD data obtained using the CMAQ-predicted aerosol concentrations. Seasonal variation of satellite-measured aerosol intensive property Angstrom exponent (a gross indicator of the aerosol size distribution) is presented for four selected sites: one each in the eastern and central parts, and two in the western part of the continental United States. Variability of Angstrom exponent at these four selected sites is analyzed in conjunction with the variation of summertime AOD (observed and modeled), mass concentration (observed and modeled) and modeled SO sub(4) average concentrations during the summer (June-August) period of the year 2001. Annual time series of Angstrom exponent data at the four selected sites show a large east-west variation. JF - Journal of Geophysical Research. D. Atmospheres AU - Roy, Biswadev AU - Mathur, Rohit AU - Gilliland, Alice B AU - Howard, Steven C AD - Atmospheric Modeling Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA Y1 - 2007/08// PY - 2007 DA - Aug 2007 PB - American Geophysical Union, 2000 Florida Ave., N.W. Washington DC 20009 USA, [mailto:service@agu.org], [URL:http://www.agu.org] VL - 112 IS - D14 SN - 0148-0227, 0148-0227 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Citation No. D14301 KW - MODIS KW - aerosol KW - CMAQ. KW - 0305 Atmospheric Composition and Structure: Aerosols and particles (0345 KW - 4801 KW - 4906) KW - 0317 Atmospheric Composition and Structure: Chemical kinetic and photochemical properties KW - 0345 Atmospheric Composition and Structure: Pollution: urban and regional (0305 KW - 0478 KW - 4251) KW - 0365 Atmospheric Composition and Structure: Troposphere: composition and chemistry KW - 0320 Atmospheric Composition and Structure: Cloud physics and chemistry. KW - Sulfates KW - Pollution monitoring KW - Atmospheric pollution models KW - Sensors KW - Remote sensing KW - Correlations KW - Air quality KW - Time series analysis KW - Optical analysis KW - Particulate matter in atmosphere KW - Aerosol size distribution KW - nephelometers KW - Nephelometers KW - extinction KW - MODIS (Moderate Resolution Imaging Spectrometer) KW - Seasonal variability KW - Seasonal variations KW - Spatial variability KW - Particle size KW - Aerosol Robotic Network (AERONET) KW - Aerosol concentration KW - Aerosols KW - Atmospheric pollution KW - Extinction KW - time series analysis KW - Troposphere KW - Satellites KW - Air quality models KW - USA KW - Satellite data KW - bears KW - Aerosol properties KW - summer KW - Optical depth of aerosols KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21040660?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research.+D.+Atmospheres&rft.atitle=A+comparison+of+CMAQ-based+aerosol+properties+with+IMPROVE%2C+MODIS%2C+and+AERONET+data&rft.au=Roy%2C+Biswadev%3BMathur%2C+Rohit%3BGilliland%2C+Alice+B%3BHoward%2C+Steven+C&rft.aulast=Roy&rft.aufirst=Biswadev&rft.date=2007-08-01&rft.volume=112&rft.issue=D14&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research.+D.+Atmospheres&rft.issn=01480227&rft_id=info:doi/10.1029%2F2006JD008085 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Aerosol concentration; Aerosol Robotic Network (AERONET); Atmospheric pollution; Atmospheric pollution models; Extinction; Correlations; Air quality; Time series analysis; Air quality models; Particulate matter in atmosphere; Satellite data; Aerosol size distribution; Nephelometers; Aerosol properties; Seasonal variability; MODIS (Moderate Resolution Imaging Spectrometer); Optical depth of aerosols; Seasonal variations; Spatial variability; Sulfates; Particle size; Pollution monitoring; Aerosols; Sensors; time series analysis; Remote sensing; Troposphere; Satellites; Optical analysis; nephelometers; bears; extinction; summer; USA DO - http://dx.doi.org/10.1029/2006JD008085 ER - TY - JOUR T1 - Reverse Osmosis Filter Use and High Arsenic Levels in Private AN - 20649339; 7566310 AB - Inorganic arsenic causes cancer, and millions of people worldwide are exposed to arsenic-contaminated water. Regulatory standards for arsenic levels in drinking water generally do not apply to private domestic wells. Reverse osmosis (RO) units commonly are used by well owners to reduce arsenic concentrations, but may not always be effective. In a survey of 102 homes in Nevada, 19 used RO devices. Pre- and post-RO filtration arsenic concentrations averaged 443 mu g/l and 87 mu g/l, respectively. The average absolute and percent reductions in arsenic concentrations after filtration were 356 mu g/l and 79%, respectively. Postfiltration concentrations were higher than 10 mu g/l in 10 homes and higher than 100 mu g/l in 4 homes. These findings provide evidence that RO filters do not guarantee safe drinking water and, despite regulatory standards, some people continue to be exposed to very high arsenic concentrations. JF - Archives of Environmental and Occupational Health AU - Water, W AU - George, C M AU - Smith, AH AU - Kalman, DA AU - Steinmaus, C M AD - Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, 1515 Clay St., 16th Floor, Oakland, CA 94612, USA, craigs@berkeley.edu Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 171 EP - 175 VL - 61 IS - 4 SN - 1933-8244, 1933-8244 KW - Pollution Abstracts KW - Filtration KW - Reverse osmosis KW - Water treatment KW - Environmental regulations KW - Water wells KW - USA, Nevada KW - Drinking water KW - Cancer KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20649339?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Environmental+and+Occupational+Health&rft.atitle=Reverse+Osmosis+Filter+Use+and+High+Arsenic+Levels+in+Private&rft.au=Water%2C+W%3BGeorge%2C+C+M%3BSmith%2C+AH%3BKalman%2C+DA%3BSteinmaus%2C+C+M&rft.aulast=Water&rft.aufirst=W&rft.date=2007-08-01&rft.volume=61&rft.issue=4&rft.spage=171&rft.isbn=&rft.btitle=&rft.title=Archives+of+Environmental+and+Occupational+Health&rft.issn=19338244&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Filtration; Reverse osmosis; Water treatment; Environmental regulations; Water wells; Drinking water; Cancer; USA, Nevada ER - TY - JOUR T1 - Rehabilitation and Flood Management Planning in a Steep, Boulder-Bedded Stream AN - 20584338; 7571457 AB - This study demonstrates the integration of rehabilitation and flood management planning in a steep, boulder-bedded stream in a coastal urban catchment on the South Island of New Zealand. The Water of Leith, the primary stream flowing through the city of Dunedin, is used as a case study. The catchment is steep, with a short time of concentration and rapid hydrologic response, and the lower stream reaches are highly channelized with floodplain encroachment, a high potential for debris flows, significant flood risks, and severely degraded aquatic habitat. Because the objectives for rehabilitation and flood management in urban catchments are often conflicting, a number of types of analyses at both the catchment and the reach scales and careful planning with stakeholder consultation were needed for successful rehabilitation efforts. This included modeling and analysis of catchment hydrology, fluvial geomorphologic assessment, analysis of water quality and aquatic ecology, hydraulic modeling and flood risk evaluation, detailed feasibility studies, and preliminary design to optimize multiple rehabilitation and flood management objectives. The study showed that all of these analyses were needed for integrated rehabilitation and flood management and that some incremental improvements in stream ecological health, aesthetics, and public recreational opportunities could be achieved in this challenging environment. These methods should be considered in a range of types of stream rehabilitation projects. JF - Environmental Management AU - Caruso, Brian S AU - Downs, Peter W AD - Office of Research and Development, Denver, CO, 80202, USA, Caruso.Brian@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 256 EP - 271 PB - Springer-Verlag, Life Science Journals, 175 Fifth Ave. New York NY 10010 USA, [mailto:orders@springer-ny.com] VL - 40 IS - 2 SN - 0364-152X, 0364-152X KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts; Sustainability Science Abstracts; Ecology Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts KW - Feasibility studies KW - water quality KW - Hydraulics KW - Flood control KW - Management Planning KW - Freshwater KW - Water quality KW - Hydrologic Models KW - Hydrology KW - New Zealand, South I., Dunedin KW - stakeholders KW - Fluvial morphology KW - Catchment Areas KW - Habitat KW - Aquatic ecology KW - Catchments KW - Environment management KW - Catchment area KW - flood plains KW - New Zealand, South I. KW - Streams KW - Ecology KW - Integration KW - Debris flow KW - Catchment hydrology KW - Islands KW - Assessments KW - Catchment basins KW - Floods KW - River basin management KW - Rehabilitation KW - Flood risk KW - PSE, New Zealand, South I. KW - Risk KW - British Isles, Scotland, Lothian, Leith KW - Flood plains KW - Recreation areas KW - M3 1010:Issues in Sustainable Development KW - SW 3010:Identification of pollutants KW - P 1000:MARINE POLLUTION KW - Q2 09171:Dynamics of lakes and rivers KW - M2 556.16:Runoff (556.16) KW - Q5 08522:Protective measures and control KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20584338?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Management&rft.atitle=Rehabilitation+and+Flood+Management+Planning+in+a+Steep%2C+Boulder-Bedded+Stream&rft.au=Caruso%2C+Brian+S%3BDowns%2C+Peter+W&rft.aulast=Caruso&rft.aufirst=Brian&rft.date=2007-08-01&rft.volume=40&rft.issue=2&rft.spage=256&rft.isbn=&rft.btitle=&rft.title=Environmental+Management&rft.issn=0364152X&rft_id=info:doi/10.1007%2Fs00267-006-0099-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Catchment area; Fluvial morphology; Debris flow; Flood control; Floods; Hydrology; Water quality; River basin management; Integration; Hydraulics; Islands; Rehabilitation; Habitat; Streams; Catchment hydrology; Flood plains; Catchment basins; Flood risk; Aquatic ecology; Feasibility studies; water quality; flood plains; Ecology; Recreation areas; Catchments; Environment management; stakeholders; Risk; Hydrologic Models; Assessments; Management Planning; Catchment Areas; British Isles, Scotland, Lothian, Leith; PSE, New Zealand, South I.; New Zealand, South I., Dunedin; New Zealand, South I.; Freshwater DO - http://dx.doi.org/10.1007/s00267-006-0099-8 ER - TY - JOUR T1 - Susceptibility of a northern Gulf of Mexico estuary to hypoxia: An analysis using box models AN - 20488793; 7538802 AB - The extent of hypoxia and the physical factors affecting development and maintenance of hypoxia were examined for Pensacola Bay, Florida (USA) by conducting monthly water quality surveys for 3years (2002-2004) and by constructing salt-and-water balance box models using the resulting data. We also analyzed data from earlier summer probabilistic water quality surveys (1996-1999). Hypoxia (O sub(2)<2.0mgL super(-) super(1)) affected an average of 24% (range=16-36%) of the Bay bottom during 1996-1999 summer surveys; similar results were obtained using the 2002-2004 monthly survey data. The water column in Pensacola Bay was usually well-stratified, apparently as a result of the low amplitude (<50cm) diurnal tide, which provides low mixing energy. Vertical diffusivity at the pycnocline was between 0.002 and 0.02cm super(2)s super(-) super(1), 10-fold less than comparable estimates for Chesapeake Bay, Maryland/Virginia. Residual (sub-tidal) estuarine circulation was sluggish, with landward velocity in the bottom layer between 1 and 4cms super(-) super(1) during summer. The observed physical transport regime severely limits exchange of bottom waters and is very conducive to development of hypoxia. Net non-conservative O sub(2) fluxes and physical O sub(2) inputs were generally in a dynamic balance during summer, such that the median imbalance, the accumulation or depletion of O sub(2), was only 11% of the non-conservative flux. Computed net non-conservative O sub(2) fluxes for the lower water column and sediments were generally low relative to other estuaries (<0.5g O sub(2)m super(-) super(2)d super(-) super(1)), indicating an absence of eutrophic conditions. This suggests that the current extent of hypoxia in Pensacola Bay may be largely attributable to natural susceptibility to hypoxia resulting from physical factors. Balanced O sub(2) metabolism or net autotrophy below the pycnocline was observed for some segments of the Bay. We hypothesize that O sub(2) production resulting from photosynthesis below the pycnocline sometimes offset O sub(2) consumption in Pensacola Bay bottom waters, potentially reducing development of hypoxia. JF - Estuarine, Coastal and Shelf Science AU - Hagy, J D AU - Murrell, M C AD - Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, FL 32563, USA, hagy.jim@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 239 EP - 253 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 74 IS - 1-2 SN - 0272-7714, 0272-7714 KW - Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - water quality KW - Photosynthesis KW - Eutrophic waters KW - Eutrophication KW - Pycnocline KW - Bottom Water KW - Estuarine sedimentation KW - Water quality KW - Gulfs KW - Mixing KW - ANW, USA, Virginia KW - Marine KW - ASW, USA, Florida KW - Diurnal variations KW - Estuarine dynamics KW - Estuaries KW - Water Quality KW - Surveys KW - Velocity KW - ANW, USA, Chesapeake Bay KW - ASW, USA, Florida, Pensacola Bay KW - ANW, USA, Maryland KW - Tides KW - Sediments KW - Maintenance KW - Model Studies KW - ASW, Mexico Gulf KW - Hypoxia KW - water column KW - summer KW - Diurnal tides KW - Fluctuations KW - Metabolism KW - Diffusion coefficients KW - Q5 08503:Characteristics, behavior and fate KW - SW 3010:Identification of pollutants KW - P 1000:MARINE POLLUTION KW - Q2 09170:Nearshore dynamics KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20488793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Susceptibility+of+a+northern+Gulf+of+Mexico+estuary+to+hypoxia%3A+An+analysis+using+box+models&rft.au=Hagy%2C+J+D%3BMurrell%2C+M+C&rft.aulast=Hagy&rft.aufirst=J&rft.date=2007-08-01&rft.volume=74&rft.issue=1-2&rft.spage=239&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2007.04.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Estuarine dynamics; Eutrophic waters; Pycnocline; Hypoxia; Estuarine sedimentation; Diurnal tides; Water quality; Diffusion coefficients; water quality; Diurnal variations; Photosynthesis; Eutrophication; Estuaries; Velocity; Maintenance; Sediments; Tides; summer; water column; Metabolism; Water Quality; Bottom Water; Surveys; Mixing; Fluctuations; Gulfs; Model Studies; ASW, Mexico Gulf; ASW, USA, Florida; ASW, USA, Florida, Pensacola Bay; ANW, USA, Chesapeake Bay; ANW, USA, Maryland; ANW, USA, Virginia; Marine DO - http://dx.doi.org/10.1016/j.ecss.2007.04.013 ER - TY - JOUR T1 - Estuarine-ocean exchange in a North Pacific estuary: Comparison of steady state and dynamic models AN - 20405857; 7538786 AB - Nutrient levels in coastal waters must be accurately assessed to determine the nutrient effects of increasing populations on coastal ecosystems. To accomplish this goal, in-field data with sufficient temporal resolution are required to define nutrient sources and sinks, and to ultimately calculate nutrient budgets. Models then are required for the interpretation and analysis of data sets. To quantify the coastal ocean nitrogen input to Yaquina Bay, Oregon, nitrate concentrations were measured by a moored sensor hourly for one month during summer upwelling some distance outside the estuary entrance jetties. The time series results then were interpreted using a steady state model (Visual Plumes' PDSW) and a hydrodynamic model, the Finite Volume Coastal Ocean Model (FVCOM). The physical scales of many stream and river plumes often lie between the scales for outfall mixing zone plume models, such as those found in EPA's Visual Plumes, and larger-sized grid scales for regional circulation models like FVCOM. A potential advantage of relatively simple, steady state plume models is that they use entrainment terms to close the plume equations, theory that has proven useful in simulating turbulent plume discharges from various sources, some approaching the dimensions of rivers. Important advantages of models like FVCOM are that they are dynamic and include the effects of the Earth's rotation. The results showed that the steady-state plume model simulates observed velocity and concentration data fairly well during periods of strong discharge velocity and weak ambient coastal currents. FVCOM was judged to give better estimates under all other ambient current conditions, although the data from the mooring cannot be used to prove this assertion as stronger currents would deflect the plume away from the mooring. Nevertheless, plume models may be useful in establishing boundary and initial conditions for hydrodynamic models. JF - Estuarine, Coastal and Shelf Science AU - Frick, W E AU - Khangaonkar, T AU - Sigleo, A C AU - Yang, Z AD - Ecosystems Research Division, 960 College Station Road, Athens, GA 30605-2720, USA, frick.walter@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 1 EP - 11 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 74 IS - 1-2 SN - 0272-7714, 0272-7714 KW - Aqualine Abstracts; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Entrainment KW - Hydrodynamics KW - Ecosystems KW - Upwelling KW - Nutrients KW - Freshwater KW - Time series analysis KW - Streams KW - Plume models KW - Coastal currents KW - IN, North Pacific KW - River plumes KW - INE, USA, Oregon, Yaquina Bay KW - USA, Oregon KW - Initial conditions KW - Plumes KW - Rivers KW - Marine KW - Mathematical models KW - Chemical composition KW - Earth's rotation KW - Estuaries KW - River discharge KW - Brackish KW - Velocity KW - Atmospheric circulation KW - Coastal waters KW - Model Studies KW - Dynamic models KW - Earth rotation KW - Oceans KW - Coastal oceanography KW - Coastal ocean models KW - Hydrodynamic models KW - Nutrients (mineral) KW - Q2 09184:Composition of water KW - M2 551.465:Structure/Dynamics/Circulation (551.465) KW - SW 0835:Streamflow and runoff KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - O 2050:Chemical Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20405857?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Estuarine-ocean+exchange+in+a+North+Pacific+estuary%3A+Comparison+of+steady+state+and+dynamic+models&rft.au=Frick%2C+W+E%3BKhangaonkar%2C+T%3BSigleo%2C+A+C%3BYang%2C+Z&rft.aulast=Frick&rft.aufirst=W&rft.date=2007-08-01&rft.volume=74&rft.issue=1-2&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2007.02.019 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Earth rotation; Chemical composition; Mathematical models; River plumes; Upwelling; Estuaries; River discharge; Nutrients (mineral); Entrainment; Ecosystems; Earth's rotation; Atmospheric circulation; Coastal waters; Time series analysis; Plume models; Coastal currents; Dynamic models; Coastal oceanography; Hydrodynamic models; Coastal ocean models; Initial conditions; Rivers; Hydrodynamics; Oceans; Velocity; Nutrients; Streams; Plumes; Model Studies; IN, North Pacific; INE, USA, Oregon, Yaquina Bay; USA, Oregon; Freshwater; Brackish; Marine DO - http://dx.doi.org/10.1016/j.ecss.2007.02.019 ER - TY - JOUR T1 - Biodiversity and concentrations of airborne fungi in large US office buildings from the BASE study AN - 20191430; 7541760 AB - The Building Assessment Survey and Evaluation (BASE) study measured baseline concentrations of airborne fungi in 100 representative US office buildings in 1994-1998. Multiple samples for different sampling durations, sites, and times of the day were aggregated into building-wide indoor and outdoor average concentrations. Fungal concentrations were compared between locations (indoor vs. outdoor), sampling and analytical methods (culture vs. microscopy), and season (summer vs. winter). The arithmetic means (standard deviations) of the indoor/outdoor concentrations of culturable fungi and fungal spores were 100/680 (230/840) CFUm super(-) super(3) and 270 /6540 (1190/6780) sporem super(-) super(3), respectively. Although fewer groups were observed indoors than outdoors, at lower average concentrations (except in two buildings), site-specific and building-wide indoor measurements had higher coefficients of variation. More groups were seen in summer, and aggregated concentrations tended to be higher than in winter except for culturable Aureobasidium spp. and Botrytis spp. outdoors and non-sporulating fungi in both locations. Rankings of the predominant fungi identified by both methods were similar, but overall indoor and outdoor spore concentrations were approximately 3 and 10 times higher, respectively, than concentrations of culturable fungi. In the 44 buildings with both measurements, the indoor and outdoor total culturable fungi to fungal spore ratios (total C/S ratios) were 1.27 and 0.25, with opposite seasonal patterns. The indoor C/S ratio was higher in summer than in winter (1.47 vs. 0.86; N=29 and 15, respectively), but the outdoor ratio was lower in summer (0.19 vs. 0.36, respectively). Comparison of the number of different fungal groups and individual occurrence in buildings and samples indicated that the outdoor environment and summer season were more diverse, but the proportional contributions of the groups were very similar suggesting that the indoor and outdoor environments were related as were summer and winter seasons for each location. The extreme (e.g., 90th percentile) indoor concentrations (200CFUm super(-) super(3) and 210sporem super(-) super(3)) may provide reference values for non-complaint US office environments. JF - Atmospheric Environment AU - Tsai, F C AU - Macher, J M AU - Hung, Y Y AD - California Environmental Protection Agency, 16th Floor, 1515 Clay Street, Oakland, CA 94612, USA, ftsai@oehha.ca.gov Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 5181 EP - 5191 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 25 SN - 1352-2310, 1352-2310 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Pollution Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts KW - Fungi KW - Airborne microorganisms KW - Indoor air KW - Biological diversity KW - Biodiversity KW - Buildings KW - Botrytis KW - Fungi in air KW - Mathematics KW - USA KW - winter KW - Sulfur dioxide KW - Standard deviation KW - Microscopy KW - Aureobasidium KW - summer KW - Seasonal variability KW - Sampling KW - Spores KW - Seasonal variations KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development KW - A 01450:Environmental Pollution & Waste Treatment KW - M2 551.588:Environmental Influences (551.588) KW - K 03450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20191430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Biodiversity+and+concentrations+of+airborne+fungi+in+large+US+office+buildings+from+the+BASE+study&rft.au=Tsai%2C+F+C%3BMacher%2C+J+M%3BHung%2C+Y+Y&rft.aulast=Tsai&rft.aufirst=F&rft.date=2007-08-01&rft.volume=41&rft.issue=25&rft.spage=5181&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2006.06.069 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Standard deviation; Fungi; Microscopy; Biodiversity; Sampling; Spores; Seasonal variations; Mathematics; Indoor air; Seasonal variability; Fungi in air; Sulfur dioxide; winter; Airborne microorganisms; Biological diversity; summer; Buildings; Aureobasidium; Botrytis; USA DO - http://dx.doi.org/10.1016/j.atmosenv.2006.06.069 ER - TY - JOUR T1 - Conservation Biology and the 300th Anniversary of the Birth of Carl Linnaeus AN - 19993384; 7892997 JF - Conservation Biology AU - Sjogren-Gulve, Per AU - Langstrom, Elisabeth AU - Baldi, Andras AU - Ibisch, Pierre AU - Kati, Vassiliki AU - Livoreil, Barbara AU - Selva, Nuria AD - The Swedish Environmental Protection Agency, Department of Natural Resources, SE-106 48 Stockholm, Sweden Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 905 EP - 906 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 21 IS - 4 SN - 0888-8892, 0888-8892 KW - Ecology Abstracts; Sustainability Science Abstracts KW - Birth KW - Conservation KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19993384?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Conservation+Biology&rft.atitle=Conservation+Biology+and+the+300th+Anniversary+of+the+Birth+of+Carl+Linnaeus&rft.au=Sjogren-Gulve%2C+Per%3BLangstrom%2C+Elisabeth%3BBaldi%2C+Andras%3BIbisch%2C+Pierre%3BKati%2C+Vassiliki%3BLivoreil%2C+Barbara%3BSelva%2C+Nuria&rft.aulast=Sjogren-Gulve&rft.aufirst=Per&rft.date=2007-08-01&rft.volume=21&rft.issue=4&rft.spage=905&rft.isbn=&rft.btitle=&rft.title=Conservation+Biology&rft.issn=08888892&rft_id=info:doi/10.1111%2Fj.1523-1739.2007.00734.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Conservation; Birth DO - http://dx.doi.org/10.1111/j.1523-1739.2007.00734.x ER - TY - JOUR T1 - An Effective Way for Sustainable Economic Development of Handan City AN - 19385152; 8573347 AB - With a high - speed economic growth and population growth, it will break out together the conflicts between rapid development of economic society and shortage of resource and energy, quickening course of urbanization and delay of city infrastructure construction, increased public demand for environment and weak ability of environment protection. As one of modern methods for environment management, environmental auditing is of great importance and is playing an important part in making effective use of resources, speeding up the pace of industrial structure adjustment, distributing production elements in a rational way and promoting sustainable development of economy. Therefore, to carry out environment auditing is an effective way for auditing to give scope to supervisory function and drive economy towards the path of sustainable development. JF - Environmental Science and Management AU - Jin, N AD - Handan City Environmental Protection Agency, Handan 056002, China Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 1 EP - 4 PB - China Journal, [mailto:bfhj@vip.163.com], [URL:http://bfhj.chinajournal.net.cn] VL - 32 IS - 8 SN - 1673-1212, 1673-1212 KW - Sustainability Science Abstracts KW - conflicts KW - economic development KW - Urbanization KW - Sustainable development KW - economic growth KW - Environmental protection KW - population growth KW - Economics KW - Environment management KW - infrastructure KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19385152?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Investigation+of+sequential+and+enzymatic+extraction+of+arsenic+from+drinking+water+distribution+solids+using+ICP-MS&rft.au=Creed%2C+P+A%3BGallawa%2C+C+M%3BYoung%2C+A+R%3BSchwegel%2C+CA%3BLytle%2C+D%3BSorg%2C+T+J%3BCreed%2C+J+T&rft.aulast=Creed&rft.aufirst=P&rft.date=2006-09-01&rft.volume=8&rft.issue=9&rft.spage=968&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fb604569c LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - conflicts; economic development; Urbanization; population growth; Economics; Sustainable development; economic growth; infrastructure; Environment management; Environmental protection ER - TY - JOUR T1 - Evaporative cooling feature selection for genotypic data involving interactions AN - 17690938; 7609324 AB - MOTIVATION: The development of genome-wide capabilities for genotyping has led to the practical problem of identifying the minimum subset of genetic variants relevant to the classification of a phenotype. This challenge is especially difficult in the presence of attribute interactions, noise and small sample size. METHODS: Analogous to the physical mechanism of evaporation, we introduce an evaporative cooling (EC) feature selection algorithm that seeks to obtain a subset of attributes with the optimum information temperature (i.e. the least noise). EC uses an attribute quality measure analogous to thermodynamic free energy that combines Relief-F and mutual information to evaporate (i.e. remove) noise features, leaving behind a subset of attributes that contain DNA sequence variations associated with a given phenotype. RESULTS: EC is able to identify functional sequence variations that involve interactions (epistasis) between other sequence variations that influence their association with the phenotype. This ability is demonstrated on simulated genotypic data with attribute interactions and on real genotypic data from individuals who experienced adverse events following smallpox vaccination. The EC formalism allows us to combine information entropy, energy and temperature into a single information free energy attribute quality measure that balances interaction and main effects. AVAILABILITY: Open source software, written in Java, is freely available upon request. JF - Bioinformatics AU - McKinney, BA AU - Reif, D M AU - White, B C AU - Crowe, JEJr AU - Moore, J H AD - Department of Genetics, University of Alabama School of Medicine, Birmingham, AL 35294, National Center for Computational Toxicology, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, Computational Genetics Laboratory, Department of Genetics, Dartmouth Medical School, Lebanon, NH 03756 and Program in Vaccine Sciences, Departments of Microbiology and Immunology, and Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA, brett.mckinney@gmail.com Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 2113 EP - 2120 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 23 IS - 16 SN - 1367-4803, 1367-4803 KW - Virology & AIDS Abstracts; Biotechnology and Bioengineering Abstracts KW - Temperature effects KW - Data processing KW - Thermodynamics KW - Evaporation KW - Nucleotide sequence KW - Genotyping KW - Algorithms KW - Vaccination KW - Free energy KW - Smallpox KW - Computer programs KW - software KW - Epistasis KW - Bioinformatics KW - Entropy KW - V 22310:Genetics, Taxonomy & Structure KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17690938?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioinformatics&rft.atitle=Evaporative+cooling+feature+selection+for+genotypic+data+involving+interactions&rft.au=McKinney%2C+BA%3BReif%2C+D+M%3BWhite%2C+B+C%3BCrowe%2C+JEJr%3BMoore%2C+J+H&rft.aulast=McKinney&rft.aufirst=BA&rft.date=2007-08-01&rft.volume=23&rft.issue=16&rft.spage=2113&rft.isbn=&rft.btitle=&rft.title=Bioinformatics&rft.issn=13674803&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Temperature effects; Data processing; Thermodynamics; Evaporation; Genotyping; Nucleotide sequence; Algorithms; Vaccination; Free energy; Smallpox; Computer programs; software; Epistasis; Bioinformatics; Entropy ER - TY - CPAPER T1 - Getting the Message Across: Communicating With U.S. Administration. T2 - 46th Annual Meeting of the Society of Nematologists and Annual Meeting of the American Phytopathological Society (SON/APS 2007) AN - 39414732; 4616865 JF - 46th Annual Meeting of the Society of Nematologists and Annual Meeting of the American Phytopathological Society (SON/APS 2007) AU - Gabriel, Clifford Y1 - 2007/07/28/ PY - 2007 DA - 2007 Jul 28 KW - USA KW - Public policy KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39414732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+of+the+Society+of+Nematologists+and+Annual+Meeting+of+the+American+Phytopathological+Society+%28SON%2FAPS+2007%29&rft.atitle=Getting+the+Message+Across%3A+Communicating+With+U.S.+Administration.&rft.au=Gabriel%2C+Clifford&rft.aulast=Gabriel&rft.aufirst=Clifford&rft.date=2007-07-28&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+of+the+Society+of+Nematologists+and+Annual+Meeting+of+the+American+Phytopathological+Society+%28SON%2FAPS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.nematologists.org/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assessment of an Infiltration Basin and Constructed Wetland for Removal of Pathogens from Feedlot Runoff T2 - 2007 Annual Conference of the Soil and Water Conservation Society (SWCS 2007) AN - 39507250; 4675307 JF - 2007 Annual Conference of the Soil and Water Conservation Society (SWCS 2007) AU - Rogers, Shane AU - Haines, John AU - Shanks, Orin Y1 - 2007/07/21/ PY - 2007 DA - 2007 Jul 21 KW - Artificial wetlands KW - Pathogens KW - Infiltration KW - Basins KW - Runoff KW - Wetlands KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39507250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2007%29&rft.atitle=Assessment+of+an+Infiltration+Basin+and+Constructed+Wetland+for+Removal+of+Pathogens+from+Feedlot+Runoff&rft.au=Rogers%2C+Shane%3BHaines%2C+John%3BShanks%2C+Orin&rft.aulast=Rogers&rft.aufirst=Shane&rft.date=2007-07-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.swcs.org/documents/07acProgram.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Characterization of fine particle and gaseous emissions during school bus idling. AN - 68190944; 17711211 AB - The particulate matter (PM) and gaseous emissions from six diesel school buses were determined over a simulated waiting period typical of schools in the northeastern U.S. Testing was conducted for both continuous idle and hot restart conditions using a suite of on-line particle and gas analyzers installed in the U.S. Environmental Protection Agency's Diesel Emissions Aerosol Laboratory. The specific pollutants measured encompassed total PM-2.5 mass (PM < or = 2.5 microm in aerodynamic diameter), PM-2.5 number concentration, particle size distribution, particle-surface polycyclic aromatic hydrocarbons (PAHs), and a tracer gas (1,1,1,2,3,3,3-heptafluoropropane) in the diluted sample stream. Carbon monoxide (CO), carbon dioxide, nitrogen oxides (NO(x)), total hydrocarbons (THC), oxygen, formaldehyde, and the tracer gas were also measured in the raw exhaust. Results of the study showed little difference in the measured emissions between a 10 min post-restart idle and a 10 min continuous idle with the exception of THC and formaldehyde. However, an emissions pulse was observed during engine restart. A predictive equation was developed from the experimental data, which allows a comparison between continuous idle and hot restart for NO(x), CO, PM2.5, and PAHs and which considers factors such as the restart emissions pulse and periods when the engine is not running. This equation indicates that restart is the preferred operating scenario as long as there is no extended idling after the engine is restarted. JF - Environmental science & technology AU - Kinsey, J S AU - Williams, D C AU - Dong, Y AU - Logan, R AD - United States Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, MD E343-02, Research Triangle Park, North Carolina 27711, USA. kinsey.john@epa.gov Y1 - 2007/07/15/ PY - 2007 DA - 2007 Jul 15 SP - 4972 EP - 4979 VL - 41 IS - 14 SN - 0013-936X, 0013-936X KW - Air Pollutants KW - 0 KW - Vehicle Emissions KW - Index Medicus KW - Particle Size KW - Air Pollutants -- analysis KW - Motor Vehicles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68190944?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Characterization+of+fine+particle+and+gaseous+emissions+during+school+bus+idling.&rft.au=Kinsey%2C+J+S%3BWilliams%2C+D+C%3BDong%2C+Y%3BLogan%2C+R&rft.aulast=Kinsey&rft.aufirst=J&rft.date=2007-07-15&rft.volume=41&rft.issue=14&rft.spage=4972&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-12 N1 - Date created - 2007-08-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Tissue distribution and urinary excretion of dimethylated arsenic and its metabolites in dimethylarsinic acid- or arsenate-treated rats AN - 19728533; 7540305 AB - Adult female Fisher 344 rats received drinking water containing 0, 4, 40, 100, or 200 parts per million of dimethylarsinic acid or 100 parts per million of arsenate for 14 days. Urine was collected during the last 24 h of exposure. Tissues were then taken for analysis of dimethylated and trimethylated arsenicals; urines were analyzed for these arsenicals and their thiolated derivatives. In dimethylarsinic acid-treated rats, highest concentrations of dimethylated arsenic were found in blood. In lung, liver, and kidney, concentrations of dimethylated arsenic exceeded those of trimethylated species; in urinary bladder and urine, trimethylated arsenic predominated. Dimethylthioarsinic acid and trimethylarsine sulfide were present in urine of dimethylarsinic acid-treated rats. Concentrations of dimethylated arsenicals were similar in most tissues of dimethylarsinic acid- and arsenate-treated rats, including urinary bladder which is the target for dimethylarsinic acid-induced carcinogenesis in the rat. Mean concentration of dimethylated arsenic was significantly higher (P<0.05) in urine of dimethylarsinic acid-treated rats than in arsenate-treated rats, suggesting a difference between treatment groups in the flux of dimethylated arsenic through urinary bladder. Concentrations of trimethylated arsenic concentrations were consistently higher in dimethylarsinic acid-treated rats than in arsenate-treated rats; these differences were significant (P<0.05) in liver, urinary bladder, and urine. Concentrations of dimethylthioarsinic acid and trimethylarsine sulfide were higher in urine from dimethylarsinic acid-treated rats than from arsenate-treated rats. Dimethylarsinic acid is extensively metabolized in the rat, yielding significant concentrations of trimethylated species and of thiolated derivatives. One or more of these metabolites could be the species causing alterations of cellular function that lead to tumors in the urinary bladder. JF - Toxicology and Applied Pharmacology AU - Adair, B M AU - Moore, T AU - Conklin, S D AU - Creed, J T AU - Wolf, D C AU - Thomas, D J AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, 109 Alexander Drive, Research Triangle Park, NC 27709, USA, thomas.david@epa.gov Y1 - 2007/07/15/ PY - 2007 DA - 2007 Jul 15 SP - 235 EP - 242 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 222 IS - 2 SN - 0041-008X, 0041-008X KW - Toxicology Abstracts KW - Arsenic KW - Urinary bladder KW - Metabolites KW - Tumors KW - Blood KW - Sulfide KW - Urine KW - Lung KW - Carcinogenesis KW - Kidney KW - Liver KW - Excretion KW - Drinking water KW - dimethylarsinic acid KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19728533?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Tissue+distribution+and+urinary+excretion+of+dimethylated+arsenic+and+its+metabolites+in+dimethylarsinic+acid-+or+arsenate-treated+rats&rft.au=Adair%2C+B+M%3BMoore%2C+T%3BConklin%2C+S+D%3BCreed%2C+J+T%3BWolf%2C+D+C%3BThomas%2C+D+J&rft.aulast=Adair&rft.aufirst=B&rft.date=2007-07-15&rft.volume=222&rft.issue=2&rft.spage=235&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.04.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Arsenic; Urinary bladder; Metabolites; Tumors; Sulfide; Blood; Lung; Urine; Carcinogenesis; Liver; Kidney; Excretion; Drinking water; dimethylarsinic acid DO - http://dx.doi.org/10.1016/j.taap.2007.04.012 ER - TY - CPAPER T1 - Characterization of Agrostis spp. Habitat in Central Oregon T2 - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AN - 39406643; 4608711 JF - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AU - Watrud, Lidia S AU - King, George A AU - Bollman, Mike AU - Storm, Marjorie Y1 - 2007/07/07/ PY - 2007 DA - 2007 Jul 07 KW - Habitat KW - Agrostis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39406643?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.atitle=Characterization+of+Agrostis+spp.+Habitat+in+Central+Oregon&rft.au=Watrud%2C+Lidia+S%3BKing%2C+George+A%3BBollman%2C+Mike%3BStorm%2C+Marjorie&rft.aulast=Watrud&rft.aufirst=Lidia&rft.date=2007-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.2007.botanyconference.org/engine/search/index.php?func=Abst ractTitle<r=All LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Global Expression Profiling as a Tool to Develop Molecular Markers Linked to Herbicide Stress in Arabidopsis T2 - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AN - 39399112; 4609324 JF - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AU - Das, Malay AU - Schaffner, Anton R AU - Mader, Michael T AU - Reichman, Jay R AU - Watrud, Lidia S AU - Pfleeger, Thomas G AU - Olszyk, David M Y1 - 2007/07/07/ PY - 2007 DA - 2007 Jul 07 KW - Stress KW - Herbicides KW - Profiling KW - Arabidopsis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39399112?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.atitle=Global+Expression+Profiling+as+a+Tool+to+Develop+Molecular+Markers+Linked+to+Herbicide+Stress+in+Arabidopsis&rft.au=Das%2C+Malay%3BSchaffner%2C+Anton+R%3BMader%2C+Michael+T%3BReichman%2C+Jay+R%3BWatrud%2C+Lidia+S%3BPfleeger%2C+Thomas+G%3BOlszyk%2C+David+M&rft.aulast=Das&rft.aufirst=Malay&rft.date=2007-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.2007.botanyconference.org/engine/search/index.php?func=Abst ractTitle<r=All LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Insights into the Origin and Population Genetics of Weedy Red Rice (Oryza sativa) in the United States T2 - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AN - 39394147; 4609501 JF - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AU - Londo, Jason AU - Schaal, Barbara Y1 - 2007/07/07/ PY - 2007 DA - 2007 Jul 07 KW - USA KW - Population genetics KW - Oryza sativa KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39394147?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.atitle=Insights+into+the+Origin+and+Population+Genetics+of+Weedy+Red+Rice+%28Oryza+sativa%29+in+the+United+States&rft.au=Londo%2C+Jason%3BSchaal%2C+Barbara&rft.aulast=Londo&rft.aufirst=Jason&rft.date=2007-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.2007.botanyconference.org/engine/search/index.php?func=Abst ractTitle<r=All LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Extended Fertility and Compatibility of Progeny within the Agrostis Hybridizing Complex: Implications for Transgene Escape and Persistence within Wild Populations T2 - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AN - 39371379; 4609144 JF - 2007 Joint Congress of the Botanical Society of America and American Society of Plant Biologists (Botany 2007 - Plant Biology 2007) AU - Reichman, Jay R AU - Bollman, Michael A AU - King, George A AU - Watrud, Lidia S Y1 - 2007/07/07/ PY - 2007 DA - 2007 Jul 07 KW - Fertility KW - Progeny KW - Hybridization KW - Agrostis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39371379?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.atitle=Extended+Fertility+and+Compatibility+of+Progeny+within+the+Agrostis+Hybridizing+Complex%3A+Implications+for+Transgene+Escape+and+Persistence+within+Wild+Populations&rft.au=Reichman%2C+Jay+R%3BBollman%2C+Michael+A%3BKing%2C+George+A%3BWatrud%2C+Lidia+S&rft.aulast=Reichman&rft.aufirst=Jay&rft.date=2007-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Joint+Congress+of+the+Botanical+Society+of+America+and+American+Society+of+Plant+Biologists+%28Botany+2007+-+Plant+Biology+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.2007.botanyconference.org/engine/search/index.php?func=Abst ractTitle<r=All LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - A non-steady state diagenetic model for changes in sediment biogeochemistry in response to seasonally hypoxic/anoxic conditions in the "dead zone" of the Louisiana Shelf AN - 869787245; 2011-049228 AB - Biogeochemical processes occurring near the sediment-water interface can play an important role in the establishment and persistence of hypoxic-to-anoxic conditions in areas of moderate-to-shallow water depth. Results are given in this paper for diagenetic modeling of two sites from the area on the Louisiana shelf west of the Mississippi River Delta known as the "dead zone". This is one of the largest and most studied regions where seasonal coastal hypoxia occurs. The diagenetic model was capable of generating good matches with depth profiles at both sites in the upper 8 cm. Moderate differences between predicted and observed concentrations below this depth are most likely due to the highly non-steady state conditions in this region. The model was also able to predict extremely low dissolved sulfide concentrations and bacterial sulfate reduction rates that were in good agreement with independent direct observations. A sensitivity analysis of the model to input parameters showed that the model was much more sensitive to changes in values under hypoxic conditions than norm-oxic or anoxic conditions in the overlying water. Simulations were carried out to first determine how the profiles of sediment porewater parameters and interfacial fluxes would change under differing quasi-steady state conditions where overlying dissolved oxygen concentrations and the rate of bioirrigation were varied. Next a non-steady state simulation was run to investigate how sediment biogeochemistry would change between these conditions during a hypothetical annual cycle. Results demonstrated a clear need to better understand the dynamic relationship among overlying water oxygen concentrations, the behavior of the benthic faunal community responsible for bioirrigation and sediment biogeochemistry. Abstract Copyright (2007) Elsevier, B.V. JF - Marine Chemistry AU - Morse, John W AU - Eldridge, Peter M Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 239 EP - 255 PB - Elsevier, Amsterdam VL - 106 IS - 1-2 SN - 0304-4203, 0304-4203 KW - United States KW - sediment-water interface KW - oxygen KW - ammonium ion KW - simulation KW - manganese KW - iron KW - Gulf of Mexico KW - aerobic environment KW - marine sediments KW - chemical reactions KW - sensitivity analysis KW - carbon KW - sediments KW - organic carbon KW - northern Gulf of Mexico KW - geochemistry KW - concentration KW - biochemistry KW - Mississippi Delta KW - solutes KW - hydrochemistry KW - models KW - dissolved oxygen KW - metals KW - diagenesis KW - anaerobic environment KW - North Atlantic KW - sulfides KW - pore water KW - Atlantic Ocean KW - 02C:Geochemistry of rocks, soils, and sediments KW - 07:Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/869787245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Chemistry&rft.atitle=A+non-steady+state+diagenetic+model+for+changes+in+sediment+biogeochemistry+in+response+to+seasonally+hypoxic%2Fanoxic+conditions+in+the+%22dead+zone%22+of+the+Louisiana+Shelf&rft.au=Morse%2C+John+W%3BEldridge%2C+Peter+M&rft.aulast=Morse&rft.aufirst=John&rft.date=2007-07-01&rft.volume=106&rft.issue=1-2&rft.spage=239&rft.isbn=&rft.btitle=&rft.title=Marine+Chemistry&rft.issn=03044203&rft_id=info:doi/10.1016%2Fj.marchem.2006.02.003 L2 - http://www.sciencedirect.com/science/journal/03044203 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2011-01-01 N1 - Number of references - 32 N1 - Document feature - illus. incl. 8 tables, sketch map N1 - Last updated - 2014-03-14 N1 - CODEN - MRCHBD N1 - SubjectsTermNotLitGenreText - aerobic environment; ammonium ion; anaerobic environment; Atlantic Ocean; biochemistry; carbon; chemical reactions; concentration; diagenesis; dissolved oxygen; geochemistry; Gulf of Mexico; hydrochemistry; iron; manganese; marine sediments; metals; Mississippi Delta; models; North Atlantic; northern Gulf of Mexico; organic carbon; oxygen; pore water; sediment-water interface; sediments; sensitivity analysis; simulation; solutes; sulfides; United States DO - http://dx.doi.org/10.1016/j.marchem.2006.02.003 ER - TY - JOUR T1 - Biological Assessment of Urban and Agricultural Streams in the California Central Valley AN - 746011562; 13167562 AB - This project was designed to establish baseline aquatic biological community structure and physical habitat conditions in select wadeable streams within the California Central Valley. A secondary objective was to evaluate possible water quality differences between site types and seasons. Two agricultural and two urban streams were monitored in spring and fall for two consecutive years beginning in the fall of 2002. Bioassessment sampling was conducted according to modified US EPA methods. The study included physical habitat assessment, water and sediment chemical analysis and characterization of the benthic macroinvertebrate community at each site. Water samples were analyzed for selected organophosphate insecticides, pyrethroid insecticides and herbicides, while sediment samples were analyzed for pyrethroids only. All sites had substantial physical habitat and water quality impairments, and the absence of pollution intolerant macroinvertebrates and dominance of pollution tolerant macroinvertebrates were indications of biological impairment. Due to the limited amount of water quality and pesticide data collected, it was not possible to definitively demonstrate any cause and effect relationships between BMI community structure and water quality or pesticide concentrations. Though most physical habitat parameters were similar and EPA physical habitat scores revealed on no significant differences between urban and agricultural sites (P = 0.290), a significant difference was seen in substrate embeddedness (P = 0.020). Dominant taxon found at all sites were chironomids, amphipods, and oligochaetes. Benthic macroinvertebrate metrics were significantly different between both types of sites (P = 0.001) and seasons (P = 0.014). Chironomidae taxon and those of the functional feeding group scrapers were greater at urban sites, while those of the functional feeding group filterers were greater at agricultural sites. In addition, the metric groups Chironomidae, filterers, and predators were found in greater numbers in the spring than the fall. JF - Environmental Monitoring and Assessment AU - Bacey, Juanita AU - Spurlock, Frank AD - California Environmental Protection Agency, Environmental Monitoring Branch, California Department of Pesticide Regulation, 1001 I Street, Sacramento, CA, 95812, USA, nbacey@cdpr.ca.gov Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 483 EP - 493 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 130 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Entomology Abstracts; Sustainability Science Abstracts; Pollution Abstracts; Environment Abstracts; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - water quality KW - Ecosystems KW - Macroinvertebrates KW - Water quality KW - Agricultural Chemicals KW - Insecticides KW - Pyrethroids KW - Aquatic insects KW - Environmental monitoring KW - Pollution tolerance KW - Water Quality KW - Habitat KW - EPA KW - Community composition KW - Community structure KW - Pollution monitoring KW - Chironomidae KW - dominance KW - Water sampling KW - Organophosphates KW - feeding KW - Streams KW - Oligochaeta KW - Habitats KW - Assessments KW - body mass KW - USA, California KW - Pollution KW - Urban areas KW - Sediment pollution KW - Feeding KW - Herbicides KW - Sediments KW - Water pollution KW - predators KW - Pesticides KW - Zoobenthos KW - USA, California, Central Valley KW - SW 5040:Data acquisition KW - Z 05340:Ecology and Behavior KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - ENA 05:Environmental Design & Urban Ecology KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746011562?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=Biological+Assessment+of+Urban+and+Agricultural+Streams+in+the+California+Central+Valley&rft.au=Bacey%2C+Juanita%3BSpurlock%2C+Frank&rft.aulast=Bacey&rft.aufirst=Juanita&rft.date=2007-07-01&rft.volume=130&rft.issue=1-3&rft.spage=483&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-006-9438-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Pollution monitoring; Community composition; Insecticides; Pesticides; Water quality; Zoobenthos; Aquatic insects; Water pollution; Feeding; Community structure; Habitat; Streams; Sediments; Pollution; water quality; Sediment pollution; Pollution tolerance; dominance; Water sampling; Organophosphates; feeding; Herbicides; predators; EPA; body mass; Pyrethroids; Urban areas; Habitats; Agricultural Chemicals; Ecosystems; Assessments; Water Quality; Macroinvertebrates; Chironomidae; Oligochaeta; USA, California; USA, California, Central Valley DO - http://dx.doi.org/10.1007/s10661-006-9438-8 ER - TY - JOUR T1 - Public safety aspects of pyrethroid insecticides used in West Nile virus-carrying mosquito control. AN - 70673514; 17546629 AB - West Nile virus is becoming increasingly prevalent in the USA, causing fever, encephalitis, meningitis and many fatalities. Spread of the disease is reduced by controlling the mosquito vectors by a variety of means, including the use of pyrethroid insecticides, which are currently under scrutiny for potential carcinogenic effects in humans. Pyrethrins and resmethrin, a pyrethroid, have been shown to cause tumours in rat and mouse models respectively. However, the tumours appear to be caused by liver enzyme induction and hypertrophy rather than genotoxicity, and the results are therefore unlikely to be applicable to humans. Nonetheless, for resmethrin, the US Environmental Protection Agency (EPA) has concluded that there is a likely risk of carcinogenicity in humans, requiring the manufacturers to provide more detailed data to prove that it can be used safely in vector control. Reproductive toxicity of resmethrin in the rat is also discussed. Copyright (c) 2007 Society of Chemical Industry. JF - Pest management science AU - Gammon, Derek W AD - Department of Pesticide Regulation, California EPA, Sacramento, CA, USA. dgammon@cdpr.ca.gov Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 625 EP - 627 VL - 63 IS - 7 SN - 1526-498X, 1526-498X KW - Insecticides KW - 0 KW - Pyrethrins KW - resmethrin KW - 10453-86-8 KW - Index Medicus KW - Rats KW - Animals KW - Humans KW - Carcinogenicity Tests KW - Mice KW - Male KW - Female KW - Mosquito Control -- methods KW - Insecticides -- toxicity KW - Pyrethrins -- toxicity KW - West Nile Fever -- transmission UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70673514?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pest+management+science&rft.atitle=Public+safety+aspects+of+pyrethroid+insecticides+used+in+West+Nile+virus-carrying+mosquito+control.&rft.au=Gammon%2C+Derek+W&rft.aulast=Gammon&rft.aufirst=Derek&rft.date=2007-07-01&rft.volume=63&rft.issue=7&rft.spage=625&rft.isbn=&rft.btitle=&rft.title=Pest+management+science&rft.issn=1526498X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-13 N1 - Date created - 2007-06-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Meta-analysis of nitrogen removal in riparian buffers. AN - 70668179; 17596626 AB - Riparian buffers, the vegetated region adjacent to streams and wetlands, are thought to be effective at intercepting and reducing nitrogen loads entering water bodies. Riparian buffer width is thought to be positively related to nitrogen removal effectiveness by influencing nitrogen retention or removal. We surveyed the scientific literature containing data on riparian buffers and nitrogen concentration in streams and groundwater to identify trends between nitrogen removal effectiveness and buffer width, hydrological flow path, and vegetative cover. Nitrogen removal effectiveness varied widely. Wide buffers (>50 m) more consistently removed significant portions of nitrogen entering a riparian zone than narrow buffers (0-25 m). Buffers of various vegetation types were equally effective at removing nitrogen but buffers composed of herbaceous and forest/herbaceous vegetation were more effective when wider. Subsurface removal of nitrogen was efficient, but did not appear to be related to buffer width, while surface removal of nitrogen was partly related to buffer width. The mass of nitrate nitrogen removed per unit length of buffer did not differ by buffer width, flow path, or buffer vegetation type. Our meta-analysis suggests that buffer width is an important consideration in managing nitrogen in watersheds. However, the inconsistent effects of buffer width and vegetation on nitrogen removal suggest that soil type, subsurface hydrology (e.g., soil saturation, groundwater flow paths), and subsurface biogeochemistry (organic carbon supply, nitrate inputs) also are important factors governing nitrogen removal in buffers. JF - Journal of environmental quality AU - Mayer, Paul M AU - Reynolds, Steven K AU - McCutchen, Marshall D AU - Canfield, Timothy J AD - USEPA, Office of Research and Development, National Risk Management Research Lab., Ground Water and Ecosystems Restoration Division, Ada, OK 74821, USA. mayer.paul@epa.gov PY - 2007 SP - 1172 EP - 1180 VL - 36 IS - 4 SN - 0047-2425, 0047-2425 KW - Nitrates KW - 0 KW - Water KW - 059QF0KO0R KW - Nitrogen KW - N762921K75 KW - Index Medicus KW - Water -- analysis KW - Nitrates -- analysis KW - Rivers KW - Ecosystem KW - Nitrogen -- analysis KW - Water Pollution -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70668179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+quality&rft.atitle=Meta-analysis+of+nitrogen+removal+in+riparian+buffers.&rft.au=Mayer%2C+Paul+M%3BReynolds%2C+Steven+K%3BMcCutchen%2C+Marshall+D%3BCanfield%2C+Timothy+J&rft.aulast=Mayer&rft.aufirst=Paul&rft.date=2007-07-01&rft.volume=36&rft.issue=4&rft.spage=1172&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+quality&rft.issn=00472425&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-16 N1 - Date created - 2007-06-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Occurrence of antibiotic-resistant uropathogenic Escherichia coli clonal group A in wastewater effluents. AN - 70662388; 17483270 AB - Isolates of Escherichia coli belonging to clonal group A (CGA), a recently described disseminated cause of drug-resistant urinary tract infections in humans, were present in four of seven sewage effluents collected from geographically dispersed areas of the United States. All 15 CGA isolates (1% of the 1,484 isolates analyzed) exhibited resistance to trimethoprim-sulfamethoxazole (TMP-SMZ), accounting for 19.5% of the 77 TMP-SMZ-resistant isolates. Antimicrobial resistance patterns, virulence traits, O:H serotypes, and phylogenetic groupings were compared for CGA and selected non-CGA isolates. The CGA isolates exhibited a wider diversity of resistance profiles and somatic antigens than that found in most previous characterizations of this clonal group. This is the first report of recovery from outside a human host of E. coli CGA isolates with virulence factor and antibiotic resistance profiles typical of CGA isolates from a human source. The occurrence of "human-type" CGA in wastewater effluents demonstrates a potential mode for the dissemination of this clonal group in the environment, with possible secondary transmission to new human or animal hosts. JF - Applied and environmental microbiology AU - Boczek, Laura A AU - Rice, Eugene W AU - Johnston, Brian AU - Johnson, James R AD - US Environmental Protection Agency, Cincinnati, OH, USA. Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 4180 EP - 4184 VL - 73 IS - 13 SN - 0099-2240, 0099-2240 KW - AtpA protein, E coli KW - 0 KW - DNA, Bacterial KW - Escherichia coli Proteins KW - Sewage KW - Fimbriae Proteins KW - 147680-16-8 KW - Trimethoprim, Sulfamethoxazole Drug Combination KW - 8064-90-2 KW - Index Medicus KW - Urinary Tract Infections -- microbiology KW - Phylogeny KW - Urinary Tract Infections -- etiology KW - Genes, Bacterial KW - DNA, Bacterial -- isolation & purification KW - Humans KW - Trimethoprim, Sulfamethoxazole Drug Combination -- pharmacology KW - Bacterial Typing Techniques KW - Base Sequence KW - Escherichia coli Infections -- microbiology KW - Virulence -- genetics KW - DNA, Bacterial -- genetics KW - Drug Resistance, Bacterial -- genetics KW - Fimbriae Proteins -- genetics KW - Electrophoresis, Gel, Pulsed-Field KW - Escherichia coli Infections -- etiology KW - Random Amplified Polymorphic DNA Technique KW - Escherichia coli Proteins -- genetics KW - Escherichia coli -- isolation & purification KW - Sewage -- microbiology KW - Escherichia coli -- pathogenicity KW - Escherichia coli -- drug effects KW - Escherichia coli -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70662388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Occurrence+of+antibiotic-resistant+uropathogenic+Escherichia+coli+clonal+group+A+in+wastewater+effluents.&rft.au=Boczek%2C+Laura+A%3BRice%2C+Eugene+W%3BJohnston%2C+Brian%3BJohnson%2C+James+R&rft.aulast=Boczek&rft.aufirst=Laura&rft.date=2007-07-01&rft.volume=73&rft.issue=13&rft.spage=4180&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-14 N1 - Date created - 2007-06-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Appl Environ Microbiol. 2000 Oct;66(10):4555-8 [11010916] Clin Infect Dis. 2005 Apr 15;40(8):1101-7 [15791508] Ann Intern Med. 2001 Jul 3;135(1):41-50 [11434731] N Engl J Med. 2001 Oct 4;345(14):1007-13 [11586952] N Engl J Med. 2001 Oct 4;345(14):1055-7 [11586959] Lancet. 2002 Jun 29;359(9325):2249-51 [12103291] Antimicrob Agents Chemother. 2002 Aug;46(8):2540-5 [12121930] Eur J Clin Microbiol Infect Dis. 2003 Apr;22(4):242-5 [12709838] Am J Med. 2003 Oct 1;115(5):358-64 [14553870] J Clin Microbiol. 2004 Jun;42(6):2618-22 [15184442] Appl Microbiol. 1969 Nov;18(5):918-24 [5370461] N Z Med J. 1976 Jul 14;84(567):15-8 [787846] Antimicrob Agents Chemother. 1990 Apr;34(4):515-8 [2188583] Clin Infect Dis. 2005 Jan 15;40(2):251-7 [15655743] Emerg Infect Dis. 2005 Jan;11(1):141-5 [15705341] J Infect Dis. 2005 Apr 1;191(7):1040-9 [15747237] Antimicrob Agents Chemother. 2001 May;45(5):1402-6 [11302802] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Evaluating the NMDA-glutamate receptor as a site of action for toluene, in vivo. AN - 70623817; 17420219 AB - Acute exposure to toluene and other volatile organic solvents results in neurotoxicity characterized by nervous system depression, cognitive and motor impairment, and alterations in visual function. In vitro, toluene disrupts the function of N-methyl-D-aspartate (NMDA)-glutamate receptors, indicating that effects on NMDA receptor function may contribute to toluene neurotoxicity. NMDA-glutamate receptors are widely present in the visual system and contribute to pattern-elicited visual-evoked potentials (VEPs) in rodents, a measure that is altered by toluene exposure. The present study tested the hypothesis that effects on NMDA receptors contribute to toluene-induced alterations in pattern-elicited VEPs. Prior to examining the effects of NMDA receptor agonists and antagonists on toluene-exposed animals, a dose-range study was conducted to determine the optimal dose for NMDA (agonist) and MK801 (antagonist). Dose levels of 2.5 mg/kg NMDA and 0.1 mg/kg MK801 were selected from these initial studies. In the second study, Long-Evans rats were exposed to toluene by inhalation, and VEPs were measured during toluene exposure in the presence or absence of NMDA or MK801. Pattern-elicited VEPs were collected by exposing rats to a sinusoidal pattern modulated at a temporal frequency of 4.55 Hz. Following collection of baseline VEPs, rats were injected with either saline, NMDA (2.5 mg/kg, ip), or MK801 (0.1 mg/kg, ip) and 10 min later were exposed to air or toluene (2000 ppm). VEP amplitudes were calculated for 1x (F1) and 2x stimulus frequency (F2). The F2 amplitude was reduced by approximately 60, 60, and 50% in the toluene-exposed groups (TOL): SALINE/TOL (n = 11), NMDA/TOL (2.5 mg/kg; n = 13), and NMDA/TOL (10 mg/kg, n = 11), respectively. Thus, NMDA (2.5 and 10 mg/kg) did not significantly affect toluene-mediated F2 amplitude effects. Administration of 0.1 mg/kg MK801 prior to toluene exposure blocked the F2 amplitude decreases caused by toluene (n = 9). However, when 0.1 mg/kg MK801 was administered 20 min after the onset of toluene exposure, toluene-mediated F2 amplitude decreases persisted despite the challenge by MK801. These data support the hypothesis that acute actions of toluene on pattern-elicited VEPs involve NMDA receptors. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Bale, Ambuja S AU - Jackson, Meredith D AU - Krantz, Quentin Todd AU - Benignus, Vernon A AU - Bushnell, Philip J AU - Shafer, Timothy J AU - Boyes, William K AD - Neurotoxicology Division, MD B105-05, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 159 EP - 166 VL - 98 IS - 1 SN - 1096-6080, 1096-6080 KW - Excitatory Amino Acid Antagonists KW - 0 KW - Receptors, N-Methyl-D-Aspartate KW - Solvents KW - Toluene KW - 3FPU23BG52 KW - Dizocilpine Maleate KW - 6LR8C1B66Q KW - Index Medicus KW - Rats KW - Animals KW - Evoked Potentials, Visual -- drug effects KW - Rats, Long-Evans KW - Male KW - Excitatory Amino Acid Antagonists -- pharmacology KW - Dizocilpine Maleate -- pharmacology KW - Toluene -- antagonists & inhibitors KW - Receptors, N-Methyl-D-Aspartate -- agonists KW - Receptors, N-Methyl-D-Aspartate -- drug effects KW - Receptors, N-Methyl-D-Aspartate -- antagonists & inhibitors KW - Toluene -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70623817?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Evaluating+the+NMDA-glutamate+receptor+as+a+site+of+action+for+toluene%2C+in+vivo.&rft.au=Bale%2C+Ambuja+S%3BJackson%2C+Meredith+D%3BKrantz%2C+Quentin+Todd%3BBenignus%2C+Vernon+A%3BBushnell%2C+Philip+J%3BShafer%2C+Timothy+J%3BBoyes%2C+William+K&rft.aulast=Bale&rft.aufirst=Ambuja&rft.date=2007-07-01&rft.volume=98&rft.issue=1&rft.spage=159&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-06 N1 - Date created - 2007-06-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Exposure reconstruction for reducing uncertainty in risk assessment: example using MTBE biomarkers and a simple pharmacokinetic model. AN - 70613882; 17564841 AB - Adverse health risks from environmental agents are generally related to average (long-term) exposures. Because a given individual's contact with a pollutant is highly variable and dependent on activity patterns, local sources and exposure pathways, simple 'snapshot' measurements of surrounding environmental media may not accurately assign the exposure level. Furthermore, susceptibility to adverse effects from contaminants is considered highly variable in the population so that even similar environmental exposure levels may result in differential health outcomes in different individuals. The use of biomarker measurements coupled to knowledge of rates of uptake, metabolism and elimination has been suggested as a remedy for reducing this type of uncertainty. To demonstrate the utility of such an approach, we invoke results from a series of controlled human exposure tests and classical first-order rate kinetic calculations to estimate how well spot measurements of methyl tertiary butyl ether and the primary metabolite, tertiary butyl alcohol, can be expected to predict different hypothetical scenarios of previous exposures. We found that blood and breath biomarker measurements give similar results and that the biological damping effect of the metabolite production gives more stable estimates of previous exposure. We also explore the value of a potential urinary biomarker, 2-hydroxyisobutyrate suggested in the literature. We find that individual biomarker measurements are a valuable tool in reconstruction of previous exposures and that a simple pharmacokinetic model can identify the time frames over which an exogenous chemical and the related chemical biomarker are useful. These techniques could be applied to broader ranges of environmental contaminants to assess cumulative exposure risks if ADME (Absorption, Distribution, Metabolization and Excretion) is understood and systemic biomarkers can be measured. JF - Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals AU - Pleil, J D AU - Kim, D AU - Prah, J D AU - Rappaport, S M AD - Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA. pleil@unc.edu PY - 2007 SP - 331 EP - 348 VL - 12 IS - 4 SN - 1354-750X, 1354-750X KW - Biomarkers KW - 0 KW - Hydroxybutyrates KW - Methyl Ethers KW - methyl tert-butyl ether KW - 29I4YB3S89 KW - 2-hydroxyisobutyric acid KW - DMW250U2HF KW - tert-Butyl Alcohol KW - MD83SFE959 KW - Index Medicus KW - Hydroxybutyrates -- urine KW - Humans KW - Models, Biological KW - Occupational Exposure -- analysis KW - Breath Tests KW - Risk Assessment KW - tert-Butyl Alcohol -- analysis KW - Methyl Ethers -- adverse effects KW - Methyl Ethers -- pharmacokinetics KW - Biomarkers -- analysis KW - Environmental Exposure -- analysis KW - Biomarkers -- urine KW - Methyl Ethers -- analysis KW - Environmental Exposure -- adverse effects KW - Biomarkers -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70613882?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biomarkers+%3A+biochemical+indicators+of+exposure%2C+response%2C+and+susceptibility+to+chemicals&rft.atitle=Exposure+reconstruction+for+reducing+uncertainty+in+risk+assessment%3A+example+using+MTBE+biomarkers+and+a+simple+pharmacokinetic+model.&rft.au=Pleil%2C+J+D%3BKim%2C+D%3BPrah%2C+J+D%3BRappaport%2C+S+M&rft.aulast=Pleil&rft.aufirst=J&rft.date=2007-07-01&rft.volume=12&rft.issue=4&rft.spage=331&rft.isbn=&rft.btitle=&rft.title=Biomarkers+%3A+biochemical+indicators+of+exposure%2C+response%2C+and+susceptibility+to+chemicals&rft.issn=1354750X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-24 N1 - Date created - 2007-06-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - In vitro metabolism of the fungicide and environmental contaminant trans-bromuconazole and implications for risk assessment. AN - 70613205; 17573638 AB - trans-Bromuconazole is a chiral chemical representative of a class of triazole derivatives known to inhibit specific fungal cytochrome P-450 (CYP) reactions. Kinetic measurements and delineation of metabolic pathways for triazole chemicals within in vitro hepatic microsomes are needed for accurate risk assessment and predictive in vivo physiological modeling. The studies described here were conducted with rat liver microsomes to determine Michaelis-Menten saturation kinetic parameters (Vmax and KM) for trans-bromuconazole using both substrate depletion and product formation reaction velocities. Kinetic parameters determined for trans-bromuconazole depletion at varying protein levels incubated at physiological temperature 37 degrees C resulted in a KM value of 1.69 microM and a Vmax value of 1398 pmol/min/mg protein. The concomitant linear formation of two metabolites identified using liquid chromatography/time-of-flight mass spectrometry (LC/MS-TOF) and LC-MS/MS indicated hydroxylation of the trans-bromuconazole dichlorophenyl ring moiety. KM values determined for the hydroxylated metabolites were 0.87 and 1.03 microM, with Vmax values of 449 and 694 pmol/min/mg protein, respectively. Chemical inhibition assays and studies conducted with individual purified human recombinant enzymes indicated the CYP3A subfamily was primarily responsible for biotransformation of the parent substrate. Additionally, trans-bromuconazole was found to undergo stereoselective metabolism as evidenced by a change in the enantiomeric ratio (trans-/trans+) with respect to time. JF - Journal of toxicology and environmental health. Part A AU - Mazur, Christopher S AU - Kenneke, John F AU - Tebes-Stevens, Caroline AU - Okino, Miles S AU - Lipscomb, John C AD - Ecosystems Research Division, National Exposure Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Athens, Georgia 30605, USA. mazur.chris@epa.gov Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 1241 EP - 1250 VL - 70 IS - 14 SN - 1528-7394, 1528-7394 KW - Fungicides, Industrial KW - 0 KW - Triazoles KW - Index Medicus KW - Rats KW - Regression Analysis KW - Animals KW - Rats, Sprague-Dawley KW - In Vitro Techniques KW - Metabolic Clearance Rate KW - Male KW - Risk Assessment KW - Microsomes, Liver -- metabolism KW - Fungicides, Industrial -- metabolism KW - Triazoles -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70613205?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=In+vitro+metabolism+of+the+fungicide+and+environmental+contaminant+trans-bromuconazole+and+implications+for+risk+assessment.&rft.au=Mazur%2C+Christopher+S%3BKenneke%2C+John+F%3BTebes-Stevens%2C+Caroline%3BOkino%2C+Miles+S%3BLipscomb%2C+John+C&rft.aulast=Mazur&rft.aufirst=Christopher&rft.date=2007-07-01&rft.volume=70&rft.issue=14&rft.spage=1241&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-19 N1 - Date created - 2007-06-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Predicting age-appropriate pharmacokinetics of six volatile organic compounds in the rat utilizing physiologically based pharmacokinetic modeling. AN - 70611096; 17426107 AB - The capability of physiologically based pharmacokinetic models to incorporate age-appropriate physiological and chemical-specific parameters was utilized to predict changes in internal dosimetry for six volatile organic compounds (VOCs) across different ages of rats. Typical 6-h animal inhalation exposures to 50 and 500 ppm perchloroethylene, trichloroethylene, benzene, chloroform, methylene chloride, or methyl ethyl ketone (MEK) were simulated for postnatal day 10 (PND10), 2-month-old (adult), and 2-year-old (aged) rats. With the exception of MEK, predicted venous blood concentrations of VOCs in the aged rat were equal or up to 1.5-fold higher when compared to the adult rat at both exposure levels, whereas levels were predicted to be up to 3.8-fold higher in the case of PND10 at 50 ppm. Predicted blood levels of MEK were similar in the adult and aged rat, but were more than 5-fold and 30-fold greater for PND10 rats at 500 and 50 ppm, respectively, reflecting high water solubility along with lower metabolic capability and faster ventilation rate per unit body weight (BW) of PND10 animals. Steady-state blood levels of VOCs, simulated by modeling constant exposure, were predicted to be achieved in the order PND10 > adult > aged, largely due to increasing fat volume. The dose metric, total amount metabolized per unit liver volume was generally much lower in PND10 than in adult rats. The blood:air partition coefficient, fat volume, and fat blood flow were identified as critical determinants for the predicted differences in venous blood concentrations between the adult and aged. The lower metabolic capability, largely due to a smaller liver size, and faster ventilation rate per unit BW of PND10 animals contribute the most to the differences between PND10 and adult rats. This study highlights the pharmacokinetic differences and the relevant parameters that may contribute to differential susceptibility to the toxic effects of VOCs across life stages of the rat. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Rodriguez, Chester E AU - Mahle, Deirdre A AU - Gearhart, Jeff M AU - Mattie, David R AU - Lipscomb, John C AU - Cook, Robert S AU - Barton, Hugh A AD - US Environmental Protection Agency, Office of Research and Development, National Center for Computational Toxicology, Research Triangle Park, North Carolina 27711, USA. Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 43 EP - 56 VL - 98 IS - 1 SN - 1096-6080, 1096-6080 KW - Organic Chemicals KW - 0 KW - Cytochrome P-450 Enzyme System KW - 9035-51-2 KW - Index Medicus KW - Rats KW - Animals KW - Adipose Tissue -- metabolism KW - Respiratory Mechanics KW - Algorithms KW - Cytochrome P-450 Enzyme System -- metabolism KW - Models, Statistical KW - Forecasting KW - Blood-Air Barrier -- physiology KW - Tissue Distribution KW - Regional Blood Flow -- physiology KW - Aging -- metabolism KW - Organic Chemicals -- toxicity KW - Organic Chemicals -- pharmacokinetics KW - Pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70611096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Predicting+age-appropriate+pharmacokinetics+of+six+volatile+organic+compounds+in+the+rat+utilizing+physiologically+based+pharmacokinetic+modeling.&rft.au=Rodriguez%2C+Chester+E%3BMahle%2C+Deirdre+A%3BGearhart%2C+Jeff+M%3BMattie%2C+David+R%3BLipscomb%2C+John+C%3BCook%2C+Robert+S%3BBarton%2C+Hugh+A&rft.aulast=Rodriguez&rft.aufirst=Chester&rft.date=2007-07-01&rft.volume=98&rft.issue=1&rft.spage=43&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-06 N1 - Date created - 2007-06-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The application of non-default uncertainty factors in the U.S. EPA's Integrated Risk Information System (IRIS). Part I: UF(L), UF(S), and "other uncertainty factors". AN - 68222379; 17763048 AB - The United States Environmental Protection Agency's Integrated Risk Information System (IRIS) includes hazard identification and dose-response assessment values developed by Agency scientists. Uncertainty factors (UFs) are used in the development of IRIS values to address the lack of information in five main areas. The standard UFs account for interspecies uncertainty (UF(A)) and intraspecies variability (UF(H)). The UF(A) addresses uncertainty related to the extrapolation of data from animals to humans, whereas the UF(H) addresses variability amongst individuals (i.e., intrahuman). Additional UFs have been employed to account for database incompleteness, extrapolations from a lowest-observed-adverse-effect level in the absence of a no-observed-adverse-effect level (UF(L)), and subchronic-to-chronic extrapolation (UF(S)). A sixth UF designated as "other uncertainty factors" (UF(O)) has also been applied in place of the UF(L) to account for uncertainty with the adversity of points of departure obtained using benchmark dose modeling. This review will discuss how UF(L), UF(S), and UF(O) have been applied in IRIS assessments, along with the rationale used to describe the choice of UF values that deviate from the standard default of 10. JF - Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews AU - Stedeford, Todd AU - Zhao, Q Jay AU - Dourson, Michael L AU - Banasik, Marek AU - Hsu, Ching-Hung AD - Integrated Risk Information System, National Center for Environmental Assessment, Office of Research and Development, United States Environmental Protection Agency, Washington, DC, USA. PY - 2007 SP - 245 EP - 279 VL - 25 IS - 3 SN - 1059-0501, 1059-0501 KW - Hazardous Substances KW - 0 KW - Index Medicus KW - United States KW - United States Environmental Protection Agency KW - No-Observed-Adverse-Effect Level KW - Dose-Response Relationship, Drug KW - Risk Assessment KW - Databases, Factual KW - Hazardous Substances -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68222379?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.atitle=The+application+of+non-default+uncertainty+factors+in+the+U.S.+EPA%27s+Integrated+Risk+Information+System+%28IRIS%29.+Part+I%3A+UF%28L%29%2C+UF%28S%29%2C+and+%22other+uncertainty+factors%22.&rft.au=Stedeford%2C+Todd%3BZhao%2C+Q+Jay%3BDourson%2C+Michael+L%3BBanasik%2C+Marek%3BHsu%2C+Ching-Hung&rft.aulast=Stedeford&rft.aufirst=Todd&rft.date=2007-07-01&rft.volume=25&rft.issue=3&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.issn=10590501&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-18 N1 - Date created - 2007-08-31 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Postulated carbon tetrachloride mode of action: a review. AN - 68219372; 17763046 AB - Under the 2005 U.S. EPA Guidelines for Carcinogen Risk Assessment (1), evaluations of carcinogens rely on mode of action data to better inform dose response assessments. A reassessment of carbon tetrachloride, a model hepatotoxicant and carcinogen, provides an opportunity to incorporate into the assessment biologically relevant mode of action data on its carcinogenesis. Mechanistic studies provide evidence that metabolism of carbon tetrachloride via CYP2E1 to highly reactive free radical metabolites plays a critical role in the postulated mode of action. The primary metabolites, trichloromethyl and trichloromethyl peroxy free radicals, are highly reactive and are capable of covalently binding locally to cellular macromolecules, with preference for fatty acids from membrane phospholipids. The free radicals initiate lipid peroxidation by attacking polyunsaturated fatty acids in membranes, setting off a free radical chain reaction sequence. Lipid peroxidation is known to cause membrane disruption, resulting in the loss of membrane integrity and leakage of microsomal enzymes. By-products of lipid peroxidation include reactive aldehydes that can form protein and DNA adducts and may contribute to hepatotoxicity and carcinogenicity, respectively. Natural antioxidants, including glutathione, are capable of quenching the lipid peroxidation reaction. When glutathione and other antioxidants are depleted, however, opportunities for lipid peroxidation are enhanced. Weakened cellular membranes allow sufficient leakage of calcium into the cytosol to disrupt intracellular calcium homeostasis. High calcium levels in the cytosol activate calcium-dependent proteases and phospholipases that further increase the breakdown of the membranes. Similarly, the increase in intracellular calcium can activate endonucleases that can cause chromosomal damage and also contribute to cell death. Sustained cell regeneration and proliferation following cell death may increase the likelihood of unrepaired spontaneous, lipid peroxidation- or endonuclease-derived mutations that can lead to cancer. Based on this body of scientific evidence, doses that do not cause sustained cytotoxicity and regenerative cell proliferation would subsequently be protective of liver tumors if this is the primary mode of action. To fulfill the mode of action framework, additional research may be necessary to determine alternative mode(s) of action for liver tumors formed via carbon tetrachloride exposure. JF - Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews AU - Manibusan, Mary K AU - Odin, Marc AU - Eastmond, David A AD - Office of Pesticide Programs, U.S. Environmental Protection Agency, Washington, DC 20460, United States. manibusan.mary@epa.gov PY - 2007 SP - 185 EP - 209 VL - 25 IS - 3 SN - 1059-0501, 1059-0501 KW - Antioxidants KW - 0 KW - Carcinogens KW - Free Radicals KW - Mutagens KW - Carbon Tetrachloride KW - CL2T97X0V0 KW - Index Medicus KW - Animals KW - Humans KW - Antioxidants -- therapeutic use KW - Oxidative Stress -- drug effects KW - Free Radicals -- metabolism KW - Neoplasms -- chemically induced KW - Carcinogens -- toxicity KW - Mutagens -- toxicity KW - Neoplasms -- prevention & control KW - Carbon Tetrachloride -- toxicity KW - Neoplasms -- genetics KW - Neoplasms -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68219372?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.atitle=Postulated+carbon+tetrachloride+mode+of+action%3A+a+review.&rft.au=Manibusan%2C+Mary+K%3BOdin%2C+Marc%3BEastmond%2C+David+A&rft.aulast=Manibusan&rft.aufirst=Mary&rft.date=2007-07-01&rft.volume=25&rft.issue=3&rft.spage=185&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.issn=10590501&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-18 N1 - Date created - 2007-08-31 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The chronic toxicity of alcohol alkoxylate surfactants on anaerobic granular sludge in the pulp and paper industry. AN - 68160053; 17695918 AB - The chronic toxicity of an alcohol alkoxylate surfactant used in the pulp and paper industry was observed in methanogenic consortia under unfed conditions. Methanogenic inhibition was not observed until 250 h of famine conditions while in the presence of the surfactant. The delayed onset of inhibition is likely due to the amount of time necessary for the surfactant to partition into the cellular membrane which uncouples cellular energy conservation mechanisms and exhausts internal energy reserves necessary to maintain homeostasis. JF - Environmental science & technology AU - Van Ginkel, Steven W AU - Kortekaas, Sjon J M AU - Van Lier, Jules B AD - Lettinga Associates Foundation, P.O. Box 500, 6700 AM, Wageningen, The Netherlands. van-ginkel.steve@epamail.epa.gov Y1 - 2007/07/01/ PY - 2007 DA - 2007 Jul 01 SP - 4711 EP - 4714 VL - 41 IS - 13 SN - 0013-936X, 0013-936X KW - Sewage KW - 0 KW - Surface-Active Agents KW - Index Medicus KW - Surface-Active Agents -- toxicity KW - Textile Industry KW - Anaerobiosis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68160053?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=The+chronic+toxicity+of+alcohol+alkoxylate+surfactants+on+anaerobic+granular+sludge+in+the+pulp+and+paper+industry.&rft.au=Van+Ginkel%2C+Steven+W%3BKortekaas%2C+Sjon+J+M%3BVan+Lier%2C+Jules+B&rft.aulast=Van+Ginkel&rft.aufirst=Steven&rft.date=2007-07-01&rft.volume=41&rft.issue=13&rft.spage=4711&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-12 N1 - Date created - 2007-08-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Methane seeps and mud volcanoes in Italy; gas origin, fractionation and emission to the atmosphere AN - 50151386; 2008-039811 AB - Molecular composition, CH (sub 4) isotopes and gas flux of all main terrestrial mud volcanoes and other methane seeps in Italy are being assessed for the first time. Whereas 74% of the Italian gas reservoirs are biogenic, about 80% of the seeps release thermogenic gas. Dry-seep gas generally maintains the reservoir C (sub 1) /(C (sub 2) + C (sub 3) ) "Bernard" ratio while mud volcanoes show molecular fractionation likely occurring during advective migration. Accordingly, a simple and direct use of the "Bernard" parameter might be misleading when applied to mud volcanoes as it could not always reflect the reservoir composition. Methane flux into the atmosphere from macro-seep areas is in the order of 10 (super 2) -10 (super 6) t km (super -2) y (super -1) . Microseepage is widespread throughout large areas and, on a regional scale, it provides the main methane output. A first emission estimate for the total hydrocarbon-prone area of Italy suggests levels of 10 (super 5) t y (super -1) , comparable to national sources from fossil fuel industry. Copyright 2007 by the American Geophysical Union. JF - Geophysical Research Letters AU - Etiope, Giuseppe AU - Martinelli, Giovanni AU - Caracausi, Antonio AU - Italiano, Francesco Y1 - 2007/07// PY - 2007 DA - July 2007 EP - L14303 PB - American Geophysical Union, Washington, DC VL - 34 IS - 14 SN - 0094-8276, 0094-8276 KW - concentration KW - methane KW - isotopes KW - isotope ratios KW - C-13/C-12 KW - aliphatic hydrocarbons KW - atmosphere KW - Europe KW - alkanes KW - stable isotopes KW - seepage KW - Italy KW - Southern Europe KW - gases KW - provenance KW - volatiles KW - organic compounds KW - carbon KW - hydrocarbons KW - chemical composition KW - mud volcanoes KW - chemical fractionation KW - 24:Quaternary geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50151386?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geophysical+Research+Letters&rft.atitle=Methane+seeps+and+mud+volcanoes+in+Italy%3B+gas+origin%2C+fractionation+and+emission+to+the+atmosphere&rft.au=Etiope%2C+Giuseppe%3BMartinelli%2C+Giovanni%3BCaracausi%2C+Antonio%3BItaliano%2C+Francesco&rft.aulast=Etiope&rft.aufirst=Giuseppe&rft.date=2007-07-01&rft.volume=34&rft.issue=14&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Geophysical+Research+Letters&rft.issn=00948276&rft_id=info:doi/10.1029%2F2007GL030341 L2 - http://www.agu.org/journals/gl/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 22 N1 - PubXState - DC N1 - Document feature - illus. incl. 2 tables, geol. sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - GPRLAJ N1 - SubjectsTermNotLitGenreText - aliphatic hydrocarbons; alkanes; atmosphere; C-13/C-12; carbon; chemical composition; chemical fractionation; concentration; Europe; gases; hydrocarbons; isotope ratios; isotopes; Italy; methane; mud volcanoes; organic compounds; provenance; seepage; Southern Europe; stable isotopes; volatiles DO - http://dx.doi.org/10.1029/2007GL030341 ER - TY - JOUR T1 - Substance flow analysis of mercury intentionally used in products in the United States AN - 36869141; 3539639 AB - Mercury-containing products release mercury (Hg) throughout their lifecycles, frequently in ways that are difficult to measure directly. Therefore, there are considerable uncertainties about the magnitude of mercury releases associated with products, about which products and which release pathways contribute the most to mercury releases, and about the likely impact on mercury releases of various possible interventions in the mercury content of products or in the management of mercury-containing wastes. This article presents an effort to use substance flow analysis to develop improved estimates of the environmental releases caused by mercury-containing products and to provide policy-makers with a better understanding of opportunities for reducing releases of mercury caused by products. JF - Journal of industrial ecology AU - Cain, Alexis AU - Disch, Sarah AU - Twaroski, Cliff AU - Reindl, John AU - Case, C Randy AD - US Environmental Protection Agency Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 61 EP - 76 VL - 11 IS - 3 SN - 1088-1980, 1088-1980 KW - Sociology KW - Economics KW - Mercury KW - Environment KW - Ecology KW - Product safety KW - Policy making KW - U.S.A. KW - Product quality KW - Environmental protection KW - Industry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36869141?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+industrial+ecology&rft.atitle=Substance+flow+analysis+of+mercury+intentionally+used+in+products+in+the+United+States&rft.au=Cain%2C+Alexis%3BDisch%2C+Sarah%3BTwaroski%2C+Cliff%3BReindl%2C+John%3BCase%2C+C+Randy&rft.aulast=Cain&rft.aufirst=Alexis&rft.date=2007-07-01&rft.volume=11&rft.issue=3&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=Journal+of+industrial+ecology&rft.issn=10881980&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 6431; 4339; 10238 11229; 9625 9628; 10237 10529; 3858; 4309; 433 293 14 ER - TY - JOUR T1 - Daily Simulation of Ozone and Fine Particulates over New York State: Findings and Challenges AN - 20648770; 9395057 AB - This study investigates the potential utility of the application of a photochemical modeling system in providing simultaneous forecasts of ozone (O3) and fine particulate matter (PM2.5) over New York State. To this end, daily simulations from the Community Multiscale Air Quality (CMAQ) model for three extended time periods during 2004 and 2005 have been performed, and predictions were compared with observations of ozone and total and speciated PM2.5. Model performance for 8-h daily maximum O3 was found to be similar to other forecasting systems and to be better than that for the 24-h-averaged total PM2.5. Both pollutants exhibited no seasonal differences in model performance. CMAQ simulations successfully captured the urban-rural and seasonal differences evident in observed total and speciated PM2.5 concentrations. However, total PM2.5 mass was strongly overestimated in the New York City metropolitan area, and further analysis of speciated observations and model predictions showed that most of this overprediction stems from organic aerosols and crustal material. An analysis of hourly speciated data measured in Bronx County, New York, suggests that a combination of uncertainties in vertical mixing, magnitude, and temporal allocation of emissions and deposition processes are all possible contributors to this overprediction in the complex urban area. Categorical evaluation of CMAQ simulations in terms of exceeding two different threshold levels of the air quality index (AQI) again indicates better performance for ozone than PM2.5 and better performance for lower exceedance thresholds. In most regions of New York State, the routine air quality forecasts based on observed concentrations and expert judgment show slightly better agreement with the observed distributions of AQI categories than do CMAQ simulations. However, CMAQ shows skill similar to these routine forecasts in terms of capturing the AQI tendency, that is, in predicting changes in air quality conditions. Overall, the results presented in this study reveal that additional research and development is needed to improve CMAQ simulations of PM2.5 concentrations over New York State, especially for the New York City metropolitan area. On the other hand, because CMAQ simulations capture urban-rural concentration gradients and day-to-day fluctuations in observed air quality despite systematic overpredictions in some areas, it would be useful to develop tools that combine CMAQ's predictive capability in terms of spatial concentration gradients and AQI tendencies with real-time observations of ambient pollutant levels to generate forecasts with higher temporal and spatial resolutions (e.g., county level) than those of techniques based exclusively on monitoring data. JF - Journal of Applied Meteorology AU - Hogrefe, C AU - Mathur, R AU - Hao, W AU - Civerolo, K AU - Ku, J-Y AU - Sistla, G AU - Gaza, RS AU - Sedefian, L AU - Schere, K AU - Gilliland, A AD - Atmospheric Sciences Modeling Division, National Oceanic and Atmospheric Administration, and National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, chogrefe@dec.state.ny.us Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 961 EP - 979 PB - American Meteorological Society, 45 Beacon St. VL - 46 IS - 7 SN - 0894-8763, 0894-8763 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - Particulate matter in urban air KW - Air quality KW - Particulates KW - Ozone in troposphere KW - USA, New York, New York City KW - Sulfur dioxide KW - Emissions KW - Meteorology KW - metropolitan areas KW - Seasonal variations KW - Urban areas KW - Ozone KW - Particle size KW - Aerosols KW - Atmospheric pollution KW - Organic aerosols in atmosphere KW - Simulation KW - Pollutant deposition KW - Photochemicals KW - Numerical simulations KW - Urban atmospheric pollution KW - Research programs KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20648770?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=Daily+Simulation+of+Ozone+and+Fine+Particulates+over+New+York+State%3A+Findings+and+Challenges&rft.au=Hogrefe%2C+C%3BMathur%2C+R%3BHao%2C+W%3BCiverolo%2C+K%3BKu%2C+J-Y%3BSistla%2C+G%3BGaza%2C+RS%3BSedefian%2C+L%3BSchere%2C+K%3BGilliland%2C+A&rft.aulast=Hogrefe&rft.aufirst=C&rft.date=2007-07-01&rft.volume=46&rft.issue=7&rft.spage=961&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2FJAM2520.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Ozone in troposphere; Atmospheric pollution models; Atmospheric pollution; Numerical simulations; Organic aerosols in atmosphere; Urban atmospheric pollution; Air quality; Particulate matter in urban air; Ozone; Particle size; Aerosols; Simulation; Particulates; Pollutant deposition; Sulfur dioxide; Photochemicals; Emissions; Meteorology; Seasonal variations; metropolitan areas; Research programs; Urban areas; USA, New York, New York City DO - http://dx.doi.org/10.1175/JAM2520.1 ER - TY - JOUR T1 - Environmental production functions and environmental directional distance functions AN - 20501430; 7764296 AB - This study derives the relationship between environmental production functions and environmental directional distance functions. These two approaches make different assumptions when modeling the joint production of good and bad outputs. The environmental production function credits a producer solely for expanding good output production, while the directional environmental distance function credits a producer for simultaneously increasing production of the good output and reducing production of bad outputs. Estimates of technical efficiency and pollution abatement costs are calculated using data from coal-fired power plants. These results provide the empirical basis for comparing the environmental production function to the environmental directional distance function. JF - Energy (Oxford) AU - Fare, Rolf AU - Grosskopf, Shawna AU - Pasurka Jr, Carl A AD - Department of Economics and Department of Agriculture and Resource Economics, Oregon State University, Corvallis, OR 97331, USA, pasurka.carl@epa.gov Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 1055 EP - 1066 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 32 IS - 7 SN - 0360-5442, 0360-5442 KW - Sustainability Science Abstracts; Pollution Abstracts KW - Environmental production functions KW - Environmental directional distance functions KW - Pollution abatement costs KW - Economics KW - Power plants KW - Air pollution control KW - Coal KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20501430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Energy+%28Oxford%29&rft.atitle=Environmental+production+functions+and+environmental+directional+distance+functions&rft.au=Fare%2C+Rolf%3BGrosskopf%2C+Shawna%3BPasurka+Jr%2C+Carl+A&rft.aulast=Fare&rft.aufirst=Rolf&rft.date=2007-07-01&rft.volume=32&rft.issue=7&rft.spage=1055&rft.isbn=&rft.btitle=&rft.title=Energy+%28Oxford%29&rft.issn=03605442&rft_id=info:doi/10.1016%2Fj.energy.2006.09.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Economics; Power plants; Air pollution control; Coal DO - http://dx.doi.org/10.1016/j.energy.2006.09.005 ER - TY - JOUR T1 - Observation-Based Assessment of the Impact of Nitrogen Oxides Emissions Reductions on Ozone Air Quality over the Eastern United States AN - 20500228; 7535297 AB - Ozone is produced by chemical interactions involving nitrogen oxides (NOx) and volatile organic compounds in the presence of sunlight. At high concentrations, ground-level ozone has been shown to be harmful to human health and to the environment. It has been recognized that ozone is a regional-scale problem and that regionwide control strategies would be needed to improve ozone air quality in the eastern United States. To mitigate interstate transport of ozone and its precursors, the U.S. Environmental Protection Agency issued a regional rule in 1998 known as the 'NOx State Implementation Plan (SIP) Call,' requiring 21 states in the eastern United States to reduce their summertime NOx emissions by 30 May 2004. In this paper, the effectiveness of the new emission control measures mandated by the NOx SIP Call is assessed by quantifying the changes that occurred in the daily maximum 8-h ozone concentrations measured at nearly 50 locations, most of which are rural (33 sites of the Clean Air Status and Trend Network and 16 sites of the Air Quality System), over the eastern United States. Given the strong dependence of ozone formation and accumulation on meteorological conditions, the incidence of the latter is first mitigated, and meteorologically adjusted ozone concentrations are extracted using a multiple regression technique. By examining the differences between the cumulative distribution functions of the meteorologically adjusted ozone concentrations, it is shown that ozone concentrations in the eastern United States are now on average 13% less than those prior to the NOx SIP Call. Using back-trajectory analyses, it is also shown that emission controls on the electricity-generating units located in the Ohio River Valley have contributed toward the improvement of ozone air quality in downwind regions, especially east and northeast of the Ohio River Valley. JF - Journal of Applied Meteorology and Climatology AU - Gego, E AU - Porter, P S AU - Gilliland, A AU - Rao, ST AD - 109 T.W. Alexander Drive, Room E-240D, U.S. Environmental Protection Agency (MD - E243-02), Research Triangle Park, NC 27711, st@epa.gov Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 994 EP - 1008 PB - American Meteorological Society, 45 Beacon St. Boston MA 02108-3693 USA VL - 46 IS - 7 SN - 1558-8424, 1558-8424 KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Meteorological & Geoastrophysical Abstracts KW - Regression techniques KW - Air quality KW - Nitrogen oxides emissions KW - Freshwater KW - Public health KW - Ozone in troposphere KW - Emissions KW - Volatile compounds KW - Ozone concentration KW - Meteorology KW - Climatology KW - river valleys KW - Meteorological conditions KW - Wind KW - Ozone KW - Atmospheric pollution KW - Climate KW - Emission control KW - sunlight KW - Nitrogen oxides KW - River valleys KW - Ozone formation KW - Environmental protection KW - EPA KW - USA KW - Photochemicals KW - Chemical interactions KW - Organic compounds KW - Nitrogen compounds KW - USA, Indiana, Ohio R. Valley KW - Volatile organic compounds KW - Oxides KW - Nitrogen KW - Q2 09243:Structure, mechanics and thermodynamics KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20500228?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology+and+Climatology&rft.atitle=Observation-Based+Assessment+of+the+Impact+of+Nitrogen+Oxides+Emissions+Reductions+on+Ozone+Air+Quality+over+the+Eastern+United+States&rft.au=Gego%2C+E%3BPorter%2C+P+S%3BGilliland%2C+A%3BRao%2C+ST&rft.aulast=Gego&rft.aufirst=E&rft.date=2007-07-01&rft.volume=46&rft.issue=7&rft.spage=994&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology+and+Climatology&rft.issn=15588424&rft_id=info:doi/10.1175%2FJAM2523.1 L2 - http://ams.allenpress.com/perlserv/?request=get-abstract&doi=10.1175%2FJAM2523.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Volatile compounds; Climatology; Organic compounds; River valleys; Nitrogen compounds; Oxides; Nitrogen; Public health; Ozone; Regression techniques; Ozone in troposphere; Atmospheric pollution; Ozone concentration; Nitrogen oxides emissions; Air quality; Meteorological conditions; Environmental protection; Ozone formation; Climate; Emission control; Nitrogen oxides; sunlight; EPA; Photochemicals; Emissions; Meteorology; Chemical interactions; river valleys; Volatile organic compounds; Wind; USA; USA, Indiana, Ohio R. Valley; Freshwater DO - http://dx.doi.org/10.1175/JAM2523.1 ER - TY - JOUR T1 - An improved colorimetric method for chlorine dioxide and chlorite ion in drinking water using lissamine green B and horseradish peroxidase AN - 20482869; 7516645 AB - Lissamine Green B (LGB) was carefully selected as a potential candidate for the development of a new U.S. Environmental Protection Agency (EPA) method that is intended for use at water utilities to determine chlorine dioxide (ClO2) in drinking water. Chlorine dioxide reacts with LGB in aqueous solution to decrease the absorbance of LGB in direct proportion to the ClO2 concentration. LGB was confirmed to have adequate sensitivity, and to suffer less interference than other dyes reported in the literature. The stoichiometry for the reaction between LGB and ClO2 was found not to be 1:1 and is dependent on the LGB concentration. This required calibration of each LGB stock solution and prompted the investigation of alternate means of calibration, which utilized a horseradish peroxidase (HRP)-catalyzed conversion of chlorite ion (ClO2-) to ClO2. This approach allowed the simultaneous determination of ClO2- concentration, which is also required each day at water plants that use ClO2. Studies were conducted to characterize and carefully optimize the HRP-conversion of ClO2- to ClO2 in order to yield reaction conditions that could be accomplished in less than 30min at modest cost, yet meet EPA's sensitivity and robustness requirements for routine monitoring. An assessment of method detection limit, linearity and slope (or sensitivity), precision, and accuracy in finished drinking water matrices indicated that this approach was suitable for publication as EPA Method 327.0. JF - Analytica Chimica Acta AU - Pepich, Barry V AU - Dattilio, Teri A AU - Fair, Patricia S AU - Munch, David J AU - Gordon, Gilbert AU - Kortvelyesi, Zsolt AD - Shaw Environmental, Inc., 26 W. Martin Luther King Drive, Cincinnati, OH 45268, United States, pepich.barry@epa.gov Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 37 EP - 45 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 596 IS - 1 SN - 0003-2670, 0003-2670 KW - Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Chlorine dioxide and chlorite analysis KW - Drinking water KW - Lissamine green B KW - Horseradish peroxidase KW - Chlorine KW - Utilities KW - Drinking Water KW - Calibrations KW - Assessments KW - Slopes KW - Publications KW - EPA KW - USA KW - Dyes KW - Detection Limits KW - Chlorination KW - Monitoring KW - SW 5010:Network design KW - AQ 00007:Industrial Effluents KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20482869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytica+Chimica+Acta&rft.atitle=An+improved+colorimetric+method+for+chlorine+dioxide+and+chlorite+ion+in+drinking+water+using+lissamine+green+B+and+horseradish+peroxidase&rft.au=Pepich%2C+Barry+V%3BDattilio%2C+Teri+A%3BFair%2C+Patricia+S%3BMunch%2C+David+J%3BGordon%2C+Gilbert%3BKortvelyesi%2C+Zsolt&rft.aulast=Pepich&rft.aufirst=Barry&rft.date=2007-07-01&rft.volume=596&rft.issue=1&rft.spage=37&rft.isbn=&rft.btitle=&rft.title=Analytica+Chimica+Acta&rft.issn=00032670&rft_id=info:doi/10.1016%2Fj.aca.2007.06.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - EPA; Dyes; Chlorination; Drinking water; Utilities; Drinking Water; Assessments; Calibrations; Detection Limits; Chlorine; Publications; Slopes; Monitoring; USA DO - http://dx.doi.org/10.1016/j.aca.2007.06.006 ER - TY - JOUR T1 - Modeling the Effect of Chlorine Emissions on Ozone Levels over the Eastern United States AN - 20478693; 7535284 AB - This paper presents model estimates of the effect of chlorine emissions on atmospheric ozone concentrations in the eastern United States. The model included anthropogenic molecular chlorine emissions, anthropogenic hypochlorous acid emissions from cooling towers and swimming pools, and chlorine released from sea-salt aerosols. The release of chlorine emissions from sea-salt aerosols was modeled using heterogeneous reactions involving chloride ions in aerosols and three gas-phase species. The gas-phase chlorine chemistry was combined with the Carbon Bond Mechanism and incorporated into the Community Multiscale Air Quality modeling system. Air quality model simulations were performed for July 2001 and the results obtained with and without chlorine emissions were analyzed. When chlorine emissions were included in the model, ozone concentrations increased in the Houston, Texas, and New York-New Jersey areas. The daily maximum 1-h ozone concentrations increased by up to 12 parts per billion by volume (ppbv) in the Houston area and 6 ppbv in the New York-New Jersey area. The daily maximum 8-h ozone concentrations increased by up to 8 ppbv in the Houston area and 4 ppbv in the New York-New Jersey area. The monthly average daily maximum 1-h ozone concentration increased by up to 3 ppbv in the Houston area, but the increases in the monthly average daily maximum 1-h ozone concentration in the New York-New Jersey area were small. Chlorine emissions and chemistry enhanced the volatile organic compound oxidation rates and, thereby, increased the ozone production rate. JF - Journal of Applied Meteorology and Climatology AU - Sarwar, G AU - Bhave, P V AD - Corresponding author address: Golam Sarwar, Atmospheric Modeling Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711-0000. sarwar, golam@epa.gov Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 1009 EP - 1019 PB - American Meteorological Society, 45 Beacon St. Boston MA 02108-3693 USA VL - 46 IS - 7 SN - 1558-8424, 1558-8424 KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Meteorological & Geoastrophysical Abstracts KW - Chlorophylls KW - Atmospheric pollution models KW - Chlorides KW - Anthropogenic factors KW - Chlorine KW - Air quality KW - Ozone production KW - Emissions KW - Ozone concentration KW - Meteorology KW - Chlorine emissions KW - Climatology KW - Cooling systems KW - USA, Texas, Houston KW - Ozone KW - Modelling KW - Ions KW - Aerosols KW - Climate KW - Simulation KW - Air quality models KW - Numerical simulations KW - Recreation areas KW - Oxidation KW - Atmospheric chemistry KW - USA, Texas KW - Organic compounds KW - Volatile organic compounds KW - M2 551.510.42:Air Pollution (551.510.42) KW - Q2 09185:Organic compounds KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20478693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology+and+Climatology&rft.atitle=Modeling+the+Effect+of+Chlorine+Emissions+on+Ozone+Levels+over+the+Eastern+United+States&rft.au=Sarwar%2C+G%3BBhave%2C+P+V&rft.aulast=Sarwar&rft.aufirst=G&rft.date=2007-07-01&rft.volume=46&rft.issue=7&rft.spage=1009&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology+and+Climatology&rft.issn=15588424&rft_id=info:doi/10.1175%2FJAM2519.1 L2 - http://ams.allenpress.com/perlserv/?request=get-abstract&doi=10.1175%2FJAM2519.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Chlorophylls; Aerosols; Atmospheric chemistry; Anthropogenic factors; Chlorine; Climatology; Organic compounds; Modelling; Ozone; Ozone production; Atmospheric pollution models; Numerical simulations; Oxidation; Ozone concentration; Chlorine emissions; Air quality models; Ions; Climate; Chlorides; Simulation; Air quality; Recreation areas; Emissions; Meteorology; Cooling systems; Volatile organic compounds; USA, Texas; USA, Texas, Houston DO - http://dx.doi.org/10.1175/JAM2519.1 ER - TY - JOUR T1 - Effects of missing seasonal data on estimates of period means of dry and wet deposition AN - 20349108; 7500276 AB - The current study uses resampling to investigate the impacts of cyclic seasonal behavior on 1- and 5-year period means composed from seasonal mean values in the presence of missing data. This is an empirical study using complete years of seasonal monitoring data collected in the eastern US and extracted from the clean air status and trends network (CASTNET) dry and the National Atmospheric Deposition Program/National Trends Network (NADP/NTN) wet deposition data archives. Estimators of period means with missing seasonal data are determined using means of the non-missing values as estimates of the missing data. Estimates are evaluated in terms of 95% inclusion intervals (e.g., estimates are within +/-X% of the true value >=95% of the time). For dry deposition, missing transition seasons (i.e., spring or fall) usually yield estimates of annual means that are within +/-20% of the true annual mean >=95% of the time. Missing summers or winters usually have larger impacts on estimates of annual means of dry deposited species than missing transition seasons. A missing summer has the largest impact on estimates of annual means of dry deposition for all constituents, except SO sub(2), where winter is especially important. For wet deposition, a missing season yields estimates of annual means that are within +/-30% of the true annual mean >=95% of the time. A missing summer has the largest impact on estimates of annual means of wet deposition for all constituents, except NH sub(4) super(+), where spring and fall are important. A strategy requiring at least 3 years of seasonal representation for three seasons with the fourth season having at least two seasonal values, yields estimates of wet deposition that are within +/-17% of the true 5-year means >=95% of the time for all species. Corresponding confidence statements for dry deposition results are considerably stronger, with estimates that are within +/-10% of the true 5-year mean >=95% of the time. JF - Atmospheric Environment AU - Sickles, JE AU - Shadwick, D S AD - ORD, NERL, Research Triangle Park, NC 27711, USA, sickles.joseph@epa.gov Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 4931 EP - 4939 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 23 SN - 1352-2310, 1352-2310 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Sulfur dioxide KW - winter KW - summer KW - Seasonal variability KW - Wet deposition KW - Dry deposition KW - Seasonal variations KW - P 0000:AIR POLLUTION KW - M2 551.510.3/.4:Physical Properties/Composition (551.510.3/.4) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20349108?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Effects+of+missing+seasonal+data+on+estimates+of+period+means+of+dry+and+wet+deposition&rft.au=Sickles%2C+JE%3BShadwick%2C+D+S&rft.aulast=Sickles&rft.aufirst=JE&rft.date=2007-07-01&rft.volume=41&rft.issue=23&rft.spage=4931&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.01.052 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Seasonal variability; Dry deposition; Wet deposition; winter; Sulfur dioxide; summer; Seasonal variations DO - http://dx.doi.org/10.1016/j.atmosenv.2007.01.052 ER - TY - JOUR T1 - Study on TP Autocontrol in Chemical Biological Flocculation Process AN - 20273893; 7605388 AB - Chemical biological flocculation process, one of the primary enhanced processes, is aimed to remove COD, SS and TP from wastewater mainly. In order to make the effluent quality stable, the autocontrol system of the process was constructed, in which the effluent concentration of TP was chosen as the control objectives, and the influent concentration of TP was considered at the same time. The experimental results indicate that the dosage of the PAFC can be adjusted on real time by the above autocontrol system. When the effluent concentration of TP is sustained at less than 1 mg/L, the flocculant dosage of autocontrol system can be saved by 25% compared with the manual control system, thus reducing operating cost and having better economic returns. JF - China Water & Wastewater AU - Rao, Y-F AU - Li, J-Y AU - Xia, S-Q AD - Supervision and Management Bureau, Nanhui Environmental Protection Agency, Shanghai 201300, China, fuguokai@163.com Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 28 EP - 30 VL - 23 IS - 13 SN - 1000-4602, 1000-4602 KW - Aqualine Abstracts; Water Resources Abstracts KW - Chemical Oxygen Demand KW - Flocculation KW - Effluents KW - Operating Costs KW - Wastewater Treatment KW - Wastewater KW - Control Systems KW - AQ 00007:Industrial Effluents KW - SW 3040:Wastewater treatment processes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20273893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=China+Water+%26+Wastewater&rft.atitle=Study+on+TP+Autocontrol+in+Chemical+Biological+Flocculation+Process&rft.au=Rao%2C+Y-F%3BLi%2C+J-Y%3BXia%2C+S-Q&rft.aulast=Rao&rft.aufirst=Y-F&rft.date=2007-07-01&rft.volume=23&rft.issue=13&rft.spage=28&rft.isbn=&rft.btitle=&rft.title=China+Water+%26+Wastewater&rft.issn=10004602&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Chemical Oxygen Demand; Flocculation; Operating Costs; Effluents; Wastewater Treatment; Control Systems; Wastewater ER - TY - JOUR T1 - Lethal levels of hypoxia for gulf coast estuarine animals AN - 20174081; 7954416 AB - There is increasing concern about eutrophication and subsequent hypoxia problems in estuaries. The US Environmental Protection Agency has developed Water Quality Criteria (WQC) for dissolved oxygen (DO) in saltwater for Cape Cod, MA to Cape Hatteras, NC but inadequate data exists for development of such criteria for other coastal geographic areas. We performed acute tests with two species of crustaceans and seven species of estuarine fishes native to the Gulf of Mexico to complement the data base for northeastern species. Flow-through tests were conducted for either 24- or 48-h at test temperatures from 24 to 28 degree C and at salinities from 20 to 31.5ppt. Estimated 24-h LC50 values obtained for crustaceans ranged from 1.36 mg/l for adult pink shrimp to 1.56 mg/l for 10-day-old mysids. Similarly, estimated LC50 values for fish ranged from 1.34 mg/l in one of the three tests with pinfish to 2.22 mg/l in one of the two tests with scaled sardines. The majority of mortality attributable to low DO concentrations in our experiments usually occurred within the first 4 h of exposure. LC50 values for the species tested are below the WQC recommended protective limit of 2.3 mg/l for juvenile and adult animals. JF - Marine Biology AU - Goodman, Larry R AU - Campbell, Jed G AD - US Environmental Protection Agency, 1 Sabine Island Drive, Gulf Breeze, FL, 32561, USA, goodman.larry@epa.gov Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 37 EP - 42 PB - Springer-Verlag, Heidelberger Platz 3 Berlin 14197 Germany, [mailto:subscriptions@springer.de] VL - 152 IS - 1 SN - 0025-3162, 0025-3162 KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Ecology Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Animals KW - Gulfs KW - Toxicity tests KW - Dissolved oxygen KW - Marine fish KW - Salinity KW - Marine crustaceans KW - Data bases KW - Testing Procedures KW - Estuaries KW - Brackish KW - Chemical oxygen demand KW - Environmental protection KW - water quality criteria KW - EPA KW - Lethal levels KW - Coastal zone KW - Sardinops KW - Fish KW - Crustaceans KW - Eutrophication KW - Crustaceans (mysid) KW - Brackishwater environment KW - Coasts KW - Temperature effects KW - Marine KW - Mortality KW - Decapoda KW - Dissolved Oxygen KW - Temperature KW - ASW, Mexico Gulf KW - ANW, USA, North Carolina, Cape Hatteras KW - crustaceans KW - Hypoxia KW - ANW, USA, Massachusetts, Cape Cod KW - Mortality causes KW - O 4090:Conservation and Environmental Protection KW - P 1000:MARINE POLLUTION KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08442:Population dynamics KW - SW 3030:Effects of pollution KW - Q5 08501:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20174081?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Biology&rft.atitle=Lethal+levels+of+hypoxia+for+gulf+coast+estuarine+animals&rft.au=Goodman%2C+Larry+R%3BCampbell%2C+Jed+G&rft.aulast=Goodman&rft.aufirst=Larry&rft.date=2007-07-01&rft.volume=152&rft.issue=1&rft.spage=37&rft.isbn=&rft.btitle=&rft.title=Marine+Biology&rft.issn=00253162&rft_id=info:doi/10.1007%2Fs00227-007-0685-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Marine fish; Hypoxia; Estuaries; Brackishwater environment; Marine crustaceans; Toxicity tests; Environmental protection; Dissolved oxygen; Mortality causes; Temperature effects; Mortality; Lethal levels; Chemical oxygen demand; Coasts; Animals; Eutrophication; Temperature; water quality criteria; EPA; crustaceans; Salinity; Coastal zone; Fish; Data bases; Testing Procedures; Dissolved Oxygen; Crustaceans (mysid); Gulfs; Crustaceans; Decapoda; Sardinops; ASW, Mexico Gulf; ANW, USA, North Carolina, Cape Hatteras; ANW, USA, Massachusetts, Cape Cod; Marine; Brackish DO - http://dx.doi.org/10.1007/s00227-007-0685-1 ER - TY - JOUR T1 - Seasonal variations in river discharge and nutrient export to a Northeastern Pacific estuary AN - 20043906; 8253424 AB - Seasonal variations in dissolved nitrogen and silica loadings were related to seasonal variability in river discharge. Dissolved nutrient concentrations measured weekly at three stations in the Yaquina River, Oregon from 1999 through 2001, and then monthly in 2002 were used as the basis for developing a nutrient loading regression as part of a larger agency program for evaluating nutrient processes. Because realistic models of nutrient transport require dense data sets to capture both long and short term fluctuations in nutrient concentrations, data at one freshwater station also were collected hourly for the same years using an in-stream monitor. The effects of storm events on dissolved nutrient transport were examined during three storms, including one in a high rainfall-discharge year, and two in average years, one of which followed a drought year. During the drought year (WY2001), total dissolved nitrate input was considerably less than in wetter years. Dissolved nitrate concentrations, however, were unusually high in the first winter storm runoff after the drought. The freshwater dissolved nitrate nitrogen loads varied from 40,380kgday super(-) super(1) during a high-flow storm event to 0.11kgday super(-) super(1) during late summer, low flow conditions. Dissolved silica dynamics differed from those of nitrate because during storm events, silica concentrations in the Yaquina River decreased to near zero at the storm height, probably due to dilution by near surface or overland flow, and later recovered. During the time interval studied, over 94% of the dissolved nitrate and silica were transported from the watershed during the winter months of greater rainfall, indicating that seasonality and river flow are primary factors when considering nutrient loadings from this watershed system. JF - Estuarine, Coastal and Shelf Science AU - Sigleo, A C AU - Frick, W E AD - Pacific Coastal Ecology Branch, Western Ecology Division, 2111 SE Marine Science Drive, Newport, OR 97365-5260, USA, sigleo.anne@epa.gov Y1 - 2007/07// PY - 2007 DA - July 2007 SP - 368 EP - 378 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 73 IS - 3-4 SN - 0272-7714, 0272-7714 KW - Pollution Abstracts; Aqualine Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Sustainability Science Abstracts; Water Resources Abstracts; Oceanic Abstracts; Meteorological & Geoastrophysical Abstracts KW - Seasonal Variations KW - Rainfall KW - Nutrients KW - Freshwater KW - Watersheds KW - Storms KW - River discharge variations KW - River Flow KW - Seasonal variability KW - USA, Oregon KW - Droughts KW - Seasonal variations KW - exports KW - nutrient transport KW - Chemical composition KW - Estuaries KW - River discharge KW - Brackish KW - Pollution Load KW - rivers KW - Overland flow KW - INE, USA, Oregon KW - winter KW - Nutrients (mineral) KW - Runoff KW - Nitrogen KW - Winter storms KW - Nutrient loading KW - nutrient concentrations KW - Statistical analysis KW - Drought KW - Sulfur dioxide KW - Stormwater runoff KW - silica KW - River flow KW - Nitrates KW - Silica KW - summer KW - M3 1010:Issues in Sustainable Development KW - SW 0835:Streamflow and runoff KW - Q2 09184:Composition of water KW - P 1000:MARINE POLLUTION KW - M2 556.16:Runoff (556.16) KW - AQ 00002:Water Quality KW - O 2050:Chemical Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20043906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Seasonal+variations+in+river+discharge+and+nutrient+export+to+a+Northeastern+Pacific+estuary&rft.au=Sigleo%2C+A+C%3BFrick%2C+W+E&rft.aulast=Sigleo&rft.aufirst=A&rft.date=2007-07-01&rft.volume=73&rft.issue=3-4&rft.spage=368&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2007.01.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Chemical composition; Estuaries; River discharge; Nutrients (mineral); Watersheds; Seasonal variations; Droughts; Runoff; River discharge variations; River flow; Winter storms; Statistical analysis; Seasonal variability; Drought; Overland flow; Storms; exports; nutrient transport; Nitrates; Rainfall; Nutrient loading; nutrient concentrations; rivers; winter; Sulfur dioxide; Stormwater runoff; silica; summer; Nitrogen; Seasonal Variations; Silica; Pollution Load; River Flow; Nutrients; INE, USA, Oregon; USA, Oregon; Freshwater; Brackish DO - http://dx.doi.org/10.1016/j.ecss.2007.01.015 ER - TY - JOUR T1 - super(13)C and super(15)N in microarthropods reveal little response of Douglas-fir ecosystems to climate change AN - 19806120; 7899733 AB - Understanding ecosystem carbon (C) and nitrogen (N) cycling under global change requires experiments maintaining natural interactions among soil structure, soil communities, nutrient availability, and plant growth. In model Douglas-fir ecosystems maintained for five growing seasons, elevated temperature and carbon dioxide (CO sub(2)) increased photosynthesis and increased C storage belowground but not aboveground. We hypothesized that interactions between N cycling and C fluxes through two main groups of microbes, mycorrhizal fungi (symbiotic with plants) and saprotrophic fungi (free-living), mediated ecosystem C storage. To quantify proportions of mycorrhizal and saprotrophic fungi, we measured stable isotopes in fungivorous microarthropods that efficiently censused the fungal community. Fungivorous microarthropods consumed on average 35% mycorrhizal fungi and 65% saprotrophic fungi. Elevated temperature decreased C flux through mycorrhizal fungi by 7%, whereas elevated CO sub(2) increased it by 4%. The dietary proportion of mycorrhizal fungi correlated across treatments with total plant biomass (n= 4, r super(2)= 0.96, P= 0.021), but not with root biomass. This suggests that belowground allocation increased with increasing plant biomass, but that mycorrhizal fungi were stronger sinks for recent photosynthate than roots. Low N content of needles (0.8-1.1%) and A horizon soil (0.11%) coupled with high C : N ratios of A horizon soil (25-26) and litter (36-48) indicated severe N limitation. Elevated temperature treatments increased the saprotrophic decomposition of litter and lowered litter C : N ratios. Because of low N availability of this litter, its decomposition presumably increased N immobilization belowground, thereby restricting soil N availability for both mycorrhizal fungi and plant growth. Although increased photosynthesis with elevated CO sub(2) increased allocation of C to ectomycorrhizal fungi, it did not benefit plant N status. Most N for plants and soil storage was derived from litter decomposition. N sequestration by mycorrhizal fungi and limited N release during litter decomposition by saprotrophic fungi restricted N supply to plants, thereby constraining plant growth response to the different treatments. JF - Global Change Biology AU - Hobbie, Erik A AU - Rygiewicz, Paul T AU - Johnson, Mark G AU - Moldenke, Andrew R AD - National Research Council, US Environmental Protection Agency, Corvallis, OR 97333, USA, Erik.Hobbie@unh.edu Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 1386 EP - 1397 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 13 IS - 7 SN - 1354-1013, 1354-1013 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Sustainability Science Abstracts; Ecology Abstracts KW - ecosystem response KW - food webs KW - global change KW - soil carbon KW - stable isotopes KW - Temperature effects KW - Litter KW - Isotopes KW - Photosynthesis KW - Fungi KW - Nutrient availability KW - Climatic changes KW - Roots KW - Biomass KW - Photosynthates KW - Decomposition KW - Soil KW - Carbon KW - Soil structure KW - Ectomycorrhizas KW - Plant communities KW - Carbon dioxide KW - Immobilization KW - Nitrogen KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - K 03420:Plant Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19806120?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+Change+Biology&rft.atitle=super%2813%29C+and+super%2815%29N+in+microarthropods+reveal+little+response+of+Douglas-fir+ecosystems+to+climate+change&rft.au=Hobbie%2C+Erik+A%3BRygiewicz%2C+Paul+T%3BJohnson%2C+Mark+G%3BMoldenke%2C+Andrew+R&rft.aulast=Hobbie&rft.aufirst=Erik&rft.date=2007-07-01&rft.volume=13&rft.issue=7&rft.spage=1386&rft.isbn=&rft.btitle=&rft.title=Global+Change+Biology&rft.issn=13541013&rft_id=info:doi/10.1111%2Fj.1365-2486.2007.01379.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Isotopes; Litter; Photosynthesis; Fungi; Climatic changes; Nutrient availability; Roots; Photosynthates; Biomass; Decomposition; Soil; Soil structure; Carbon; Ectomycorrhizas; Plant communities; Carbon dioxide; Immobilization; Nitrogen DO - http://dx.doi.org/10.1111/j.1365-2486.2007.01379.x ER - TY - JOUR T1 - Systemic Translocation of Particulate Matter-Associated Metals Following a Single Intratracheal Instillation in Rats AN - 19691142; 7465389 AB - Respirable ambient particulate matter (PM) exposure has been associated with an increased risk of cardiovascular disease. Direct translocation of PM-associated metals from the lungs into systemic circulation may be partly responsible. We measured elemental content of lungs, plasma, heart, and liver of healthy male WKY rats (12-15 weeks old) 4 or 24 h following a single intratracheal (IT) instillation of saline or 8.33 mg/kg of oil combustion PM (HP-12) containing a variety of transition metals with differing water and acid solubility. Tissues were digested with a combination of quaternary acid, amine, and nitric acid and analyzed using inductively coupled plasma-atomic emission spectroscopy. Lung levels of metals were lower at 24 h than at 4 h. Metals with high water solubility and relatively high concentration in HP-12 were increased in extrapulmonary organs. Water-soluble nonessential metals, like vanadium and nickel, were increased in plasma, hearts, and livers of exposed animals at both time points. Exposure-related small increases in essential metals, like zinc and manganese, were also noted in extrapulmonary tissues at both time points. Lead, with low water solubility but high acid solubility, was detected in liver only at 24-h postinstillation. Elements with low water or acid solubility, like silicon and aluminum, were not detected in extrapulmonary tissues despite decreased levels in the lung suggesting mucociliary clearance. We have shown that HP-12-associated metals translocate to systemic circulation and extrapulmonary organs following IT exposure. This translocation is dependent upon their relative levels and water solubility. Thus, following inhalation, PM-associated metals deposited in the lung may be released into systemic circulation at different rates depending on their water/acid solubility, thereby providing a means by which metals may elicit direct extrapulmonary effects. JF - Toxicological Sciences AU - Wallenborn, JGrace AU - McGee, John K AU - Schladweiler, Mette C AU - Ledbetter, Allen D AU - Kodavanti, Urmila P AD - Department of Environmental Sciences and Engineering, UNC School of Public Health, Chapel Hill, North Carolina 27599. Pulmonary Toxicology Branch, MD B143-01, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, ORD, Environmental Protection Agency, Research Triangle Park, North Carolina 27711 Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 231 EP - 239 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 98 IS - 1 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Vanadium KW - Heart KW - Inhalation KW - Silicon KW - Solubility KW - Heavy metals KW - Nickel KW - Particulate matter KW - Transition metals KW - Spectroscopy KW - Combustion KW - Oil KW - amines KW - Lung KW - Aluminum KW - Zinc KW - Liver KW - Nitric acid KW - Cardiovascular diseases KW - Trachea KW - Translocation KW - Manganese KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19691142?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Systemic+Translocation+of+Particulate+Matter-Associated+Metals+Following+a+Single+Intratracheal+Instillation+in+Rats&rft.au=Wallenborn%2C+JGrace%3BMcGee%2C+John+K%3BSchladweiler%2C+Mette+C%3BLedbetter%2C+Allen+D%3BKodavanti%2C+Urmila+P&rft.aulast=Wallenborn&rft.aufirst=JGrace&rft.date=2007-07-01&rft.volume=98&rft.issue=1&rft.spage=231&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Inhalation; Heart; Vanadium; Silicon; Solubility; Heavy metals; Particulate matter; Nickel; Transition metals; Spectroscopy; Combustion; Oil; amines; Lung; Zinc; Aluminum; Liver; Nitric acid; Cardiovascular diseases; Manganese; Translocation; Trachea ER - TY - JOUR T1 - Polybrominated Diphenyl Ethers and ortho-Substituted Polychlorinated Biphenyls as Neuroendocrine Disruptors of Vasopressin Release: Effects during Physiological Activation In Vitro and Structure-Activity Relationships AN - 19687419; 7465383 AB - The neuropeptide, vasopressin (VP) is synthesized in magnocellular neuroendocrine cells (MNCs) located within the supraoptic (SON) and paraventricular (PVN) nuclei of the mammalian hypothalamus. VP has multiple functions including maintenance of body fluid homeostasis, cardiovascular control, learning and memory, and nervous system development. Polybrominated diphenyl ethers (PBDEs), used as additive flame retardants, have been shown to interfere with hormone metabolism and function. Previously, we demonstrated that the technical polychlorinated biphenyl (PCB) mixture, Aroclor 1254, inhibits somatodendritic VP release from the SON of osmotically stimulated rats. The objectives of the current study were to test whether PBDEs affect central VP release in a similar manner and to determine the potency of several PCB and PBDE congeners in order to identify a common mode of action for these persistent chemicals. The current work shows that the commercial PBDE mixture (DE-71) significantly decreased somatodendritic VP release from rat SON punches in a strain-independent manner. In addition, the specific congeners PBDE 47 and PCB 47 (15 and 5 mu M) were also neuroactive in this system. To explore structure/activity relationships, we compared the effects of PBDE 77 with PCB 77. PBDE 77, but not PCB 77 significantly reduced VP release. These results show that like PCBs, PBDEs perturb signaling mechanisms responsible for hormone release, and that environmentally relevant PBDE congeners are more neuroactive than the commercial mixtures with noncoplanarity of these compounds playing a role in promoting neuroactivity. JF - Toxicological Sciences AU - Coburn, Cary G AU - Curras-Collazo, Margarita C AU - Kodavanti, Prasada Rao S AD - Environmental Toxicology Graduate Program, University of California, Riverside, California 92521. Cellular and Molecular Toxicology Branch, Neurotoxicology Division, NHEERL, ORD, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711. Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521 Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 178 EP - 186 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 98 IS - 1 SN - 1096-6080, 1096-6080 KW - Pollution Abstracts; Toxicology Abstracts; CSA Neurosciences Abstracts KW - Chemicals KW - Cardiovascular system KW - Physiology KW - Fire retardant chemicals KW - Homeostasis KW - Hormones KW - Polybrominated diphenyl ethers KW - Rats KW - Nervous system KW - Memory KW - Hormone release KW - Congeners KW - Aroclor 1254 KW - PCB compounds KW - Neuropeptides KW - Body fluids KW - PCB KW - structure-activity relationships KW - Learning KW - Maintenance KW - polybrominated diphenyl ethers KW - polychlorinated biphenyls KW - Vasopressin KW - Fire retardants KW - Additives KW - Structure-activity relationships KW - Metabolism KW - Signal transduction KW - N3 11028:Neuropharmacology & toxicology KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19687419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Polybrominated+Diphenyl+Ethers+and+ortho-Substituted+Polychlorinated+Biphenyls+as+Neuroendocrine+Disruptors+of+Vasopressin+Release%3A+Effects+during+Physiological+Activation+In+Vitro+and+Structure-Activity+Relationships&rft.au=Coburn%2C+Cary+G%3BCurras-Collazo%2C+Margarita+C%3BKodavanti%2C+Prasada+Rao+S&rft.aulast=Coburn&rft.aufirst=Cary&rft.date=2007-07-01&rft.volume=98&rft.issue=1&rft.spage=178&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Learning; Cardiovascular system; Homeostasis; Fire retardant chemicals; Hormones; Memory; Nervous system; polybrominated diphenyl ethers; polychlorinated biphenyls; Vasopressin; Hormone release; Congeners; Aroclor 1254; Neuropeptides; Structure-activity relationships; Metabolism; PCB; Body fluids; Signal transduction; Rats; Chemicals; Polybrominated diphenyl ethers; structure-activity relationships; Physiology; Fire retardants; Additives; PCB compounds; Maintenance ER - TY - JOUR T1 - Diatoms as indicators of isolated herbaceous wetland condition in Florida, USA AN - 19295282; 7485373 AB - Benthic, epiphytic, and phytoplanktonic diatoms, as well as soil and water physical-chemical parameters, were sampled from 70 small (average 0.86ha) isolated depressional herbaceous wetlands located along a gradient of human disturbance in peninsular Florida to (1) compare diatom assemblage structure between algal types; (2) develop biological indicators of wetland condition; (3) examine synecological relationships between diatom structure and environmental variables, with the ultimate goal of developing an index of biological integrity using a single assemblage. Collected diatom samples were enumerated to 250 valves and identified to species or subspecies. An assessment of wetland condition was made using a landscape-scale human disturbance score (Landscape Development Intensity index, LDI), calculated for each site using land use maps and GIS. Assemblages from both impaired and reference sites were compared using blocked multi-response permutation procedures, the percent similarity index, and visually examined using non-metric multidimensional scaling (NMDS). No ecologically significant compositional differences were found within sites. Mantel's test (Mantel's r=0.29, p0.50, p<0.05) were found between epiphytic NMDS site scores and soil pH, specific conductivity, water total phosphorous, and LDI, while soil pH, water color, soil TP, and turbidity were also significantly correlated (p<0.05). Metrics to assess wetland condition were developed using epiphytic abundance data. Epiphytic taxa sensitive or tolerant to human landscape modification were identified using Indicator Species Analysis, and autecological indices relating diatom sensitivity to nutrients, pH, dissolved oxygen levels, saprobity, salinity, and trophic status were calculated. Fourteen final metrics were identified, scored on an ordinal scale, and combined into the Diatom Index of Wetland Condition (DIWC). The DIWC was highly correlated with the disturbance score (Spearman's r sub(s)=-0.71, p<0.0001), although the results need to be validated. JF - Ecological Indicators AU - Lane, C R AU - Brown, M T AD - University of Florida, P.O. Box 116350, Gainesville, FL 32611-6350, United States, lane.charles@epa.gov Y1 - 2007/07// PY - 2007 DA - Jul 2007 SP - 521 EP - 540 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 7 IS - 3 SN - 1470-160X, 1470-160X KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Sustainability Science Abstracts; Ecology Abstracts KW - Data processing KW - Soil pH KW - Landscape KW - Abundance KW - Bacillariophyceae KW - Soil chemistry KW - Stress KW - Diatoms KW - Nutrients KW - Trophic status KW - Maps KW - Dissolved oxygen KW - Land use KW - Color KW - Salinity effects KW - Multidimensional scaling KW - Wetlands KW - Geographic information systems KW - pH effects KW - Turbidity KW - Algae KW - Indicator species KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - K 03450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19295282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Indicators&rft.atitle=Diatoms+as+indicators+of+isolated+herbaceous+wetland+condition+in+Florida%2C+USA&rft.au=Hilborn%2C+Elizabeth+D%3BCovert%2C+Terry+C%3BYakrus%2C+Mitchell+A%3BHarris%2C+Stephanie+I%3BDonnelly%2C+Sandra+F%3BRice%2C+Eugene+W%3BToney%2C+Sean%3BBailey%2C+Stephanie+A%3BStelma%2C+Gerard+NJr&rft.aulast=Hilborn&rft.aufirst=Elizabeth&rft.date=2006-09-01&rft.volume=72&rft.issue=9&rft.spage=5864&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Data processing; Abundance; Landscape; Soil pH; Soil chemistry; Diatoms; Stress; Nutrients; Maps; Trophic status; Land use; Dissolved oxygen; Color; Salinity effects; Multidimensional scaling; Wetlands; Geographic information systems; pH effects; Turbidity; Indicator species; Algae; Bacillariophyceae DO - http://dx.doi.org/10.1016/j.ecolind.2006.06.001 ER - TY - CPAPER T1 - Why Bring WaterSense to Your Community T2 - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AN - 39442613; 4602672 DE: JF - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AU - Lee, Virginia Y1 - 2007/06/24/ PY - 2007 DA - 2007 Jun 24 KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39442613?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.atitle=Why+Bring+WaterSense+to+Your+Community&rft.au=Lee%2C+Virginia&rft.aulast=Lee&rft.aufirst=Virginia&rft.date=2007-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences/ace/sessions/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Lead and Copper Control: Lessons Learned from the US T2 - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AN - 39435836; 4602552 JF - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AU - Schock, Michael Y1 - 2007/06/24/ PY - 2007 DA - 2007 Jun 24 KW - Lead KW - Copper KW - Heavy metals KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39435836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.atitle=Lead+and+Copper+Control%3A+Lessons+Learned+from+the+US&rft.au=Schock%2C+Michael&rft.aulast=Schock&rft.aufirst=Michael&rft.date=2007-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences/ace/sessions/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Full Cost Pricing T2 - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AN - 39394342; 4602437 JF - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AU - Shanaghan, Peter Y1 - 2007/06/24/ PY - 2007 DA - 2007 Jun 24 KW - Pricing KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39394342?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.atitle=Full+Cost+Pricing&rft.au=Shanaghan%2C+Peter&rft.aulast=Shanaghan&rft.aufirst=Peter&rft.date=2007-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences/ace/sessions/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Unsolved Problems with Corrosion and Distribution Inorganics T2 - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AN - 39329982; 4602434 JF - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AU - Schock, Michael AU - Lytle, Darren Y1 - 2007/06/24/ PY - 2007 DA - 2007 Jun 24 KW - Corrosion KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39329982?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.atitle=Unsolved+Problems+with+Corrosion+and+Distribution+Inorganics&rft.au=Schock%2C+Michael%3BLytle%2C+Darren&rft.aulast=Schock&rft.aufirst=Michael&rft.date=2007-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences/ace/sessions/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Overview of OGWDW Activities T2 - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AN - 39319187; 4602424 JF - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AU - Dougherty, Cynthia Y1 - 2007/06/24/ PY - 2007 DA - 2007 Jun 24 KW - Reviews KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39319187?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.atitle=Overview+of+OGWDW+Activities&rft.au=Dougherty%2C+Cynthia&rft.aulast=Dougherty&rft.aufirst=Cynthia&rft.date=2007-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences/ace/sessions/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Impact of the Change in Disinfectant on Lead, Brass, and Copper Components T2 - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AN - 39307489; 4602753 JF - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AU - Schock, Michael Y1 - 2007/06/24/ PY - 2007 DA - 2007 Jun 24 KW - Lead KW - Copper KW - Disinfectants KW - Heavy metals KW - Ecosystem disturbance KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39307489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.atitle=Impact+of+the+Change+in+Disinfectant+on+Lead%2C+Brass%2C+and+Copper+Components&rft.au=Schock%2C+Michael&rft.aulast=Schock&rft.aufirst=Michael&rft.date=2007-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences/ace/sessions/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Update on EPA's WaterSenseSM New Homes Initiative T2 - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AN - 39276728; 4602699 DE: JF - 2007 Annual Conference and Exposition of the American Water Works Association (ACE 07) AU - Flowers, John Y1 - 2007/06/24/ PY - 2007 DA - 2007 Jun 24 KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39276728?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.atitle=Update+on+EPA%27s+WaterSenseSM+New+Homes+Initiative&rft.au=Flowers%2C+John&rft.aulast=Flowers&rft.aufirst=John&rft.date=2007-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+07%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences/ace/sessions/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Analysis of perfluorinated carboxylic acids in soils: detection and quantitation issues at low concentrations. AN - 70563533; 17459394 AB - Methods were developed for the extraction from soil, identification, confirmation and quantitation by LC/MS/MS of trace levels of perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA). Whereas PFOA, PFNA and PFDA all can be quantitated using the method of standard additions, PFOA also can be quantitated less laboriously using 13C4-PFOA as a matrix internal standard. The impact of extract matrices on signal varied between soils and temporally during analytical runs rendering 13C4-PFOA unsuitable as a matrix internal standard for quantitating perfluorinated carboxylic acids (PFCAs) other than PFOA, which co-elutes with 13C4-PFOA. In fact, for soil extracts, quantitation of PFCAs based on external calibrations proved about as accurate as use of matrix internal standards for target analytes that do not co-elute with the matrix internal standard. Also, 13C4-PFOA should be used carefully as a matrix internal standard for trace levels of PFOA because some 13C4-PFOA standards contain trace impurities of unlabelled PFOA. When the presence of PFCAs in soil extracts is being determined by LC/MS/MS, detection limits are best defined by statistical methods that quantify the significance of contrast between analytical signal and background noise using multiple analyses. Further, when developing a calibration of low concentrations using weighted regression, the central tendency of the calibration line is best fitted using graphical depictions of error. As the MDL for the transition-product quantitation ion is approached in LC/MS/MS, relatively weak signals of transition-product confirmation ions can be used as a rejection criterion by looking for anomalously high values of the ratio of the confirmation to the quantitation ion. JF - Journal of chromatography. A AU - Washington, John W AU - Ellington, J Jackson AU - Jenkins, Thomas M AU - Evans, John J AD - USEPA, National Exposure Research Laboratory, 960 College Station Road, Athens, GA 30605, USA. Washington.John@epa.gov Y1 - 2007/06/22/ PY - 2007 DA - 2007 Jun 22 SP - 111 EP - 120 VL - 1154 IS - 1-2 SN - 0021-9673, 0021-9673 KW - Caprylates KW - 0 KW - Carboxylic Acids KW - Fluorocarbons KW - Soil Pollutants KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Caprylates -- analysis KW - Fluorocarbons -- analysis KW - Tandem Mass Spectrometry -- methods KW - Chromatography, High Pressure Liquid -- methods KW - Carboxylic Acids -- analysis KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70563533?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chromatography.+A&rft.atitle=Analysis+of+perfluorinated+carboxylic+acids+in+soils%3A+detection+and+quantitation+issues+at+low+concentrations.&rft.au=Washington%2C+John+W%3BEllington%2C+J+Jackson%3BJenkins%2C+Thomas+M%3BEvans%2C+John+J&rft.aulast=Washington&rft.aufirst=John&rft.date=2007-06-22&rft.volume=1154&rft.issue=1-2&rft.spage=111&rft.isbn=&rft.btitle=&rft.title=Journal+of+chromatography.+A&rft.issn=00219673&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-06 N1 - Date created - 2007-06-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Water analysis: emerging contaminants and current issues. AN - 70611173; 17508722 JF - Analytical chemistry AU - Richardson, Susan D AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, Athens, Georgia 30605, USA. Y1 - 2007/06/15/ PY - 2007 DA - 2007 Jun 15 SP - 4295 EP - 4323 VL - 79 IS - 12 SN - 0003-2700, 0003-2700 KW - Disinfectants KW - 0 KW - Hormones KW - Pesticides KW - Pharmaceutical Preparations KW - Sewage KW - Water Pollutants KW - Index Medicus KW - Pesticides -- analysis KW - Pesticides -- metabolism KW - Pharmaceutical Preparations -- metabolism KW - Hormones -- analysis KW - Disinfectants -- metabolism KW - Hormones -- metabolism KW - Disinfectants -- analysis KW - Pharmaceutical Preparations -- analysis KW - Water Pollutants -- toxicity KW - Sewage -- analysis KW - Water Supply -- analysis KW - Water Pollutants -- analysis KW - Water Supply -- standards KW - Water Pollutants -- metabolism KW - Sewage -- microbiology KW - Biosensing Techniques -- trends KW - Sewage -- chemistry KW - Environmental Monitoring -- standards KW - Biosensing Techniques -- methods KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70611173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Water+analysis%3A+emerging+contaminants+and+current+issues.&rft.au=Richardson%2C+Susan+D&rft.aulast=Richardson&rft.aufirst=Susan&rft.date=2007-06-15&rft.volume=79&rft.issue=12&rft.spage=4295&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=00032700&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-16 N1 - Date created - 2007-06-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Temporal moisture content variability beneath and external to a building and the potential effects on vapor intrusion risk assessment AN - 20724269; 7498129 AB - Migration of vapors from organic chemicals residing in the subsurface into overlying buildings is known as vapor intrusion. Because of the difficulty in evaluating vapor intrusion by indoor air sampling, models are often employed to determine if a potential indoor inhalation exposure pathway exists and, if such a pathway is complete, whether long-term exposure increases the occupants' risk for cancer or other toxic effects to an unacceptable level. For site-specific vapor intrusion assessments, moisture content is, at times, determined from soil cores taken in open spaces between buildings. However, there is little published information on how moisture content measured outside a building structure compares with the moisture content directly beneath the building - where the values are most critical for vapor intrusion assessments. This research begins to address these issues by investigating the movement of soil moisture next to and beneath a building at a contaminated field site and determining the effect on vapor intrusion risk assessment. A two-dimensional, variably-saturated water flow model, HYDRUS-2D, is used with 2 years of hourly, local rainfall data to simulate subsurface moisture content in the vicinity of a hypothetical 10x10-m building slab at a contaminated field site. These moisture content values are used in vapor intrusion risk assessment simulations using the Johnson and Ettinger model with instantaneous and averaged moisture contents. Results show that vapor intrusion risk assessments based on moisture content determined from soil cores taken external to a building structure may moderately-to-severely underestimate the vapor intrusion risk from beneath the structure. Soil under the edges of a slab may be influenced by rainfall events and may show reduced vapor intrusion risk as a consequence. Data from a building instrumented with subslab moisture probes showed results similar to the modeling, but with a smaller difference between the subslab and outside average moisture contents. These results indicate that, depending upon the point of vapor ingress into the structure and soil type, risk-based cleanup concentrations based on outside-of-slab or default moisture content values may not be predictive of exposure to organic vapors from below a building. JF - Science of the Total Environment AU - Tillman, F D AU - Weaver, J W AD - National Exposure Research Laboratory, Ecosystems Research Division, 960 College Station Road, Athens, GA 30605-2700, United States, Weaver.Jim@epa.gov Y1 - 2007/06/15/ PY - 2007 DA - 2007 Jun 15 SP - 1 EP - 15 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 379 IS - 1 SN - 0048-9697, 0048-9697 KW - Pollution Abstracts; Risk Abstracts; Meteorological & Geoastrophysical Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Inhalation KW - Chemicals KW - Risk assessment KW - Rainfall data KW - Rainfall KW - Indoor air KW - Soil KW - Vapors KW - Assessments KW - Cores KW - Exposure KW - Air sampling KW - soil types KW - Simulation KW - Buildings KW - Cancer KW - Model Studies KW - Risk KW - open spaces KW - Numerical simulations KW - Structure KW - water flow KW - Moisture Content KW - Soil moisture KW - P 0000:AIR POLLUTION KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - R2 23050:Environment KW - M2 556.14:Infiltration/Soil Moisture (556.14) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20724269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Science+of+the+Total+Environment&rft.atitle=Temporal+moisture+content+variability+beneath+and+external+to+a+building+and+the+potential+effects+on+vapor+intrusion+risk+assessment&rft.au=Tillman%2C+F+D%3BWeaver%2C+J+W&rft.aulast=Tillman&rft.aufirst=F&rft.date=2007-06-15&rft.volume=379&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Science+of+the+Total+Environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2007.02.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Numerical simulations; Rainfall data; Indoor air; Soil moisture; Risk assessment; Chemicals; Inhalation; soil types; Rainfall; Simulation; Buildings; Cancer; Soil; Vapors; open spaces; Air sampling; water flow; Risk; Cores; Assessments; Exposure; Structure; Moisture Content; Model Studies DO - http://dx.doi.org/10.1016/j.scitotenv.2007.02.003 ER - TY - CPAPER T1 - The Causal Analysis / Diagnosis Decision Information System T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39373261; 4596760 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Norton, Susan B Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Information systems KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39373261?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=The+Causal+Analysis+%2F+Diagnosis+Decision+Information+System&rft.au=Norton%2C+Susan+B&rft.aulast=Norton&rft.aufirst=Susan&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Interactive Conceptual Models in CADDIS T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39366657; 4596761 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Schofield, Kate AU - Norton, Susan B AU - Catanzaro, Donald Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39366657?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Interactive+Conceptual+Models+in+CADDIS&rft.au=Schofield%2C+Kate%3BNorton%2C+Susan+B%3BCatanzaro%2C+Donald&rft.aulast=Schofield&rft.aufirst=Kate&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Reach-Scale Geomorphology Affects Organic Matter and Consumer d super(13)C in a Forested Piedmont Stream (South Carolina, USA) T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39360403; 4596403 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Walters, David M AU - Fritz, Ken M AU - Phillips, Don Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - USA, North Carolina, Piedmont KW - USA, South Carolina KW - Organic matter KW - Geomorphology KW - Streams KW - Consumers KW - Carbon isotopes KW - Fluvial morphology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39360403?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Reach-Scale+Geomorphology+Affects+Organic+Matter+and+Consumer+d+super%2813%29C+in+a+Forested+Piedmont+Stream+%28South+Carolina%2C+USA%29&rft.au=Walters%2C+David+M%3BFritz%2C+Ken+M%3BPhillips%2C+Don&rft.aulast=Walters&rft.aufirst=David&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Predicting Pesticide Concentrations from Macroinvertebrate Observations T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39354709; 4596223 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Yuan, Lester L AU - Pollard, Amina I AU - Carlisle, Daren M Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Pesticides KW - Zoobenthos KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39354709?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Predicting+Pesticide+Concentrations+from+Macroinvertebrate+Observations&rft.au=Yuan%2C+Lester+L%3BPollard%2C+Amina+I%3BCarlisle%2C+Daren+M&rft.aulast=Yuan&rft.aufirst=Lester&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Biological Indicators of Watershed Health: A Resource and Portal for EPA Bioassessment Activities T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39349523; 4596748 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Davis, Wayne S Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - EPA KW - Watersheds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39349523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Biological+Indicators+of+Watershed+Health%3A+A+Resource+and+Portal+for+EPA+Bioassessment+Activities&rft.au=Davis%2C+Wayne+S&rft.aulast=Davis&rft.aufirst=Wayne&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Longitudinal Zonation of Benthic Macroinvertebrates in Three Large Reservoirs of the Upper Missouri River T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39347025; 4596425 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Scharold, Jill AU - Corry, Timothy D AU - Bolgrien, David W AU - Angradi, Ted R Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - USA, Missouri R. KW - Zonation KW - Reservoirs KW - Rivers KW - Zoobenthos KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39347025?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Longitudinal+Zonation+of+Benthic+Macroinvertebrates+in+Three+Large+Reservoirs+of+the+Upper+Missouri+River&rft.au=Scharold%2C+Jill%3BCorry%2C+Timothy+D%3BBolgrien%2C+David+W%3BAngradi%2C+Ted+R&rft.aulast=Scharold&rft.aufirst=Jill&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Do Post-Mining Constructed Channels Replace Functional Attributes of Headwater Streams? T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39343733; 4596440 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Fritz, Ken AU - Fulton, Stephanie AU - Johnson, Brent AU - Barton, Chris AU - Jack, Jeff AU - Word, David AU - Burke, Roger Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Channels KW - Streams KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39343733?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Do+Post-Mining+Constructed+Channels+Replace+Functional+Attributes+of+Headwater+Streams%3F&rft.au=Fritz%2C+Ken%3BFulton%2C+Stephanie%3BJohnson%2C+Brent%3BBarton%2C+Chris%3BJack%2C+Jeff%3BWord%2C+David%3BBurke%2C+Roger&rft.aulast=Fritz&rft.aufirst=Ken&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Home on the Big River: Assessing Habitat Condition in the Great Rivers of the Central United States T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39343113; 4596267 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Taylor, Debra L AU - Angradi, Theodore R AU - Batterman, Sharon L AU - Bolgrien, David W AU - Hill, Brian H AU - Jicha, Terri M AU - Moffett, Mary F AU - Pearson, Mark S Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - USA, Indiana, Great R. KW - USA KW - New Zealand, South I., Kahurangi Natl. Park, Big R. KW - Habitat KW - Rivers KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39343113?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Home+on+the+Big+River%3A+Assessing+Habitat+Condition+in+the+Great+Rivers+of+the+Central+United+States&rft.au=Taylor%2C+Debra+L%3BAngradi%2C+Theodore+R%3BBatterman%2C+Sharon+L%3BBolgrien%2C+David+W%3BHill%2C+Brian+H%3BJicha%2C+Terri+M%3BMoffett%2C+Mary+F%3BPearson%2C+Mark+S&rft.aulast=Taylor&rft.aufirst=Debra&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Detecting Climate Change: A Classification of Bioindicators to Distinguish Effects T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39342001; 4596547 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Bierwagen, Britta G AU - Julius, Susan AU - Barbour, Michael T AU - Gerritsen, Jeroen AU - Hamilton, Anna T AU - Paul, Michael Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Bioindicators KW - Climatic changes KW - Classification KW - Indicator species KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39342001?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Detecting+Climate+Change%3A+A+Classification+of+Bioindicators+to+Distinguish+Effects&rft.au=Bierwagen%2C+Britta+G%3BJulius%2C+Susan%3BBarbour%2C+Michael+T%3BGerritsen%2C+Jeroen%3BHamilton%2C+Anna+T%3BPaul%2C+Michael&rft.aulast=Bierwagen&rft.aufirst=Britta&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Optimizing Stormwater Management Retrofits Based on Impervious Surface Connections to Sewers T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39341847; 4596476 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Roy, Allison H AU - Shuster, William D Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Sewers KW - Water management KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39341847?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Optimizing+Stormwater+Management+Retrofits+Based+on+Impervious+Surface+Connections+to+Sewers&rft.au=Roy%2C+Allison+H%3BShuster%2C+William+D&rft.aulast=Col%C3%B3n&rft.aufirst=Dalizza&rft.date=2006-08-15&rft.volume=40&rft.issue=16&rft.spage=4976&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Using Structural Equation Modeling to Investigate the Direct and Indirect Effects of Nutrients on Stream Integrity T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39328972; 4596599 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Griffith, Michael B AU - Daniel, F Bernard Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Nutrients KW - Mathematical models KW - Streams KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39328972?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Using+Structural+Equation+Modeling+to+Investigate+the+Direct+and+Indirect+Effects+of+Nutrients+on+Stream+Integrity&rft.au=Griffith%2C+Michael+B%3BDaniel%2C+F+Bernard&rft.aulast=Griffith&rft.aufirst=Michael&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Status of Compensatory Mitigation for Lost Stream Functions in EPA Region 4 T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39328100; 4596752 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Fulton, Stephanie Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - EPA KW - Mitigation KW - Streams KW - Stream functions KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39328100?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=The+Status+of+Compensatory+Mitigation+for+Lost+Stream+Functions+in+EPA+Region+4&rft.au=Fulton%2C+Stephanie&rft.aulast=Fulton&rft.aufirst=Stephanie&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Science to Inform Policy on Protection of Headwater Streams T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39327787; 4596682 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Fritz, Ken Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Streams KW - Policies KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39327787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Science+to+Inform+Policy+on+Protection+of+Headwater+Streams&rft.au=Fritz%2C+Ken&rft.aulast=Fritz&rft.aufirst=Ken&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Where have All the Mayflies Gone? Patterns of Impacts to Appalachian Ephemeroptera T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39327625; 4596490 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Pond, Gregory J AU - Passmore, Margaret E Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Aquatic insects KW - Ephemeroptera KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39327625?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Where+have+All+the+Mayflies+Gone%3F+Patterns+of+Impacts+to+Appalachian+Ephemeroptera&rft.au=Pond%2C+Gregory+J%3BPassmore%2C+Margaret+E&rft.aulast=Pond&rft.aufirst=Gregory&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Nestedness in Riverine Freshwater Mussel Communities T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39310374; 4596235 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Rashleigh, Brenda Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Freshwater environments KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39310374?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Nestedness+in+Riverine+Freshwater+Mussel+Communities&rft.au=Rashleigh%2C+Brenda&rft.aulast=Rashleigh&rft.aufirst=Brenda&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Do Bottom-Feeders Know their Place? Macro and Micro Habitat Affinities of Invertebrate Populations Inhabiting a Mountain Meadow Stream Reach in Northern Idaho T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39309732; 4596640 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Hornig, Evan Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - USA, Idaho KW - Invertebrates KW - Habitat KW - Mountains KW - Affinity KW - Meadows KW - Streams KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39309732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Do+Bottom-Feeders+Know+their+Place%3F+Macro+and+Micro+Habitat+Affinities+of+Invertebrate+Populations+Inhabiting+a+Mountain+Meadow+Stream+Reach+in+Northern+Idaho&rft.au=Hornig%2C+Evan&rft.aulast=Hornig&rft.aufirst=Evan&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of Geospatial Data to Predict Downstream Impacts of Coal Mining in an Appalachian Watershed T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39302920; 4596386 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Johnson, Brent R AU - Haas, Adam AU - Fritz, Ken M Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Coal KW - Watersheds KW - Downstream KW - Mining KW - Data processing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39302920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Use+of+Geospatial+Data+to+Predict+Downstream+Impacts+of+Coal+Mining+in+an+Appalachian+Watershed&rft.au=Johnson%2C+Brent+R%3BHaas%2C+Adam%3BFritz%2C+Ken+M&rft.aulast=Johnson&rft.aufirst=Brent&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Indices of Taxon-by-Taxon Disagreement between Observed and Expected Assemblages T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39298286; 4596491 DE: JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Van Sickle, John Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39298286?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=Indices+of+Taxon-by-Taxon+Disagreement+between+Observed+and+Expected+Assemblages&rft.au=Van+Sickle%2C+John&rft.aulast=Van+Sickle&rft.aufirst=John&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Paradox of the Plankton: Community Structure Promotes Blooms T2 - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AN - 39263883; 4596729 JF - 55th Annual Meeting of the North American Benthological Society (NABS 2007) AU - Orme-Zavaleta, Jennifer AU - Eldridge, Peter M AU - Rossignol, Phil A Y1 - 2007/06/03/ PY - 2007 DA - 2007 Jun 03 KW - Plankton KW - Community structure KW - Community composition KW - Phytoplankton KW - Algal blooms KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39263883?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.atitle=The+Paradox+of+the+Plankton%3A+Community+Structure+Promotes+Blooms&rft.au=Orme-Zavaleta%2C+Jennifer%3BEldridge%2C+Peter+M%3BRossignol%2C+Phil+A&rft.aulast=Orme-Zavaleta&rft.aufirst=Jennifer&rft.date=2007-06-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2007/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Prospects for enhanced ground water recharge via infiltration of urban storm water runoff; a case study AN - 884413741; 2011-069643 JF - Journal of Soil and Water Conservation AU - Shuster, W D AU - Gehring, R AU - Gerken, J Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 129 EP - 136 PB - Soil Conservation Society of America, Ankeny, IA VL - 62 IS - 3 SN - 0022-4561, 0022-4561 KW - United States KW - Europe KW - ecosystems KW - Switzerland KW - urban environment KW - ground water KW - Hamilton County Ohio KW - Central Europe KW - drainage basins KW - Cincinnati Ohio KW - storms KW - Ohio KW - soils KW - hydrology KW - best management practices KW - rainfall KW - measurement KW - case studies KW - recharge KW - infiltration KW - runoff KW - Shepherd Creek basin KW - hydraulic conductivity KW - design KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/884413741?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Soil+and+Water+Conservation&rft.atitle=Prospects+for+enhanced+ground+water+recharge+via+infiltration+of+urban+storm+water+runoff%3B+a+case+study&rft.au=Shuster%2C+W+D%3BGehring%2C+R%3BGerken%2C+J&rft.aulast=Shuster&rft.aufirst=W&rft.date=2007-06-01&rft.volume=62&rft.issue=3&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=Journal+of+Soil+and+Water+Conservation&rft.issn=00224561&rft_id=info:doi/ L2 - http://www.jswconline.org/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 22 N1 - PubXState - IA N1 - Document feature - illus. incl. 1 table, sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - JSWCA3 N1 - SubjectsTermNotLitGenreText - best management practices; case studies; Central Europe; Cincinnati Ohio; design; drainage basins; ecosystems; Europe; ground water; Hamilton County Ohio; hydraulic conductivity; hydrology; infiltration; measurement; Ohio; rainfall; recharge; runoff; Shepherd Creek basin; soils; storms; Switzerland; United States; urban environment ER - TY - JOUR T1 - Mechanistic Computational Model of Ovarian Steroidogenesis to Predict Biochemical Responses to Endocrine Active Compounds AN - 831173340; 13866083 AB - Sex steroids, which have an important role in a wide range of physiological and pathological processes, are synthesized primarily in the gonads and adrenal glands through a series of enzyme-mediated reactions. The activity of steroidogenic enzymes can be altered by a variety of endocrine active compounds (EAC), some of which are therapeutics and others that are environmental contaminants. A steady-state computational model of the intraovarian metabolic network was developed to predict the synthesis and secretion of testosterone (T) and estradiol (E2), and their responses to EAC. Model predictions were compared to data from an in vitro steroidogenesis assay with ovary explants from a small fish model, the fathead minnow. Model parameters were estimated using an iterative optimization algorithm. Model-predicted concentrations of T and E2 closely correspond to the time-course data from baseline (control) experiments, and dose-response data from experiments with the EAC, fadrozole (FAD). A sensitivity analysis of the model parameters identified specific transport and metabolic processes that most influence the concentrations of T and E2, which included uptake of cholesterol into the ovary, secretion of androstenedione (AD) from the ovary, and conversions of AD to T, and AD to estrone (E1). The sensitivity analysis also indicated the E1 pathway as the preferred pathway for E2 synthesis, as compared to the T pathway. Our study demonstrates the feasibility of using the steroidogenesis model to predict T and E2 concentrations, in vitro, while reducing model complexity with a steady-state assumption. This capability could be useful for pharmaceutical development and environmental health assessments with EAC. JF - Annals of Biomedical Engineering AU - Breen, Michael S AU - Villeneuve, Daniel L AU - Breen, Miyuki AU - Ankley, Gerald T AU - Conolly, Rory B AD - National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, Mail B205-01, Research Triangle Park, NC, 27711, USA, breen.michael@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 970 EP - 981 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 35 IS - 6 SN - 0090-6964, 0090-6964 KW - Biotechnology and Bioengineering Abstracts KW - Adrenal glands KW - Androstenedione KW - Mathematical models KW - Data processing KW - endocrine active compounds KW - Secretion KW - metabolic networks KW - Algorithms KW - Enzymes KW - Steroid hormones KW - Cholesterol KW - Steroidogenesis KW - Estradiol KW - flavin-adenine dinucleotide KW - Testosterone KW - Pharmaceuticals KW - Gonads KW - Ovaries KW - Contaminants KW - Explants KW - Estrone KW - Sex KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/831173340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Biomedical+Engineering&rft.atitle=Mechanistic+Computational+Model+of+Ovarian+Steroidogenesis+to+Predict+Biochemical+Responses+to+Endocrine+Active+Compounds&rft.au=Breen%2C+Michael+S%3BVilleneuve%2C+Daniel+L%3BBreen%2C+Miyuki%3BAnkley%2C+Gerald+T%3BConolly%2C+Rory+B&rft.aulast=Breen&rft.aufirst=Michael&rft.date=2007-06-01&rft.volume=35&rft.issue=6&rft.spage=970&rft.isbn=&rft.btitle=&rft.title=Annals+of+Biomedical+Engineering&rft.issn=00906964&rft_id=info:doi/10.1007%2Fs10439-007-9309-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Adrenal glands; Androstenedione; Data processing; Mathematical models; endocrine active compounds; Secretion; metabolic networks; Algorithms; Enzymes; Cholesterol; Steroid hormones; Steroidogenesis; Estradiol; Testosterone; flavin-adenine dinucleotide; Pharmaceuticals; Gonads; Ovaries; Contaminants; Explants; Sex; Estrone DO - http://dx.doi.org/10.1007/s10439-007-9309-7 ER - TY - JOUR T1 - Assessment of Isolated Wetland Condition in Florida Using Epiphytic Diatoms at Genus, Species, and Subspecies Taxonomic Resolution AN - 754881740; 13410672 AB - Diatoms are useful indicators of aquatic conditions, and metrics based on published autecological indicator values have been developed utilizing their sensitivities to various ambient physical and chemical conditions. The autecological values often differ within genera, and indeed within species taxonomic levels, requiring identification to subspecies taxonomic level for accurate application. This study was conducted to determine if autecological metrics, and ultimately indices of biotic integrity, could be developed using mean autecological values at the genus, species, and subspecies taxonomic levels, and to investigate the potential benefits of increased taxonomic resolution. Sixty-nine isolated herbaceous wetlands in various land use modalities in peninsular Florida were sampled a single time for epiphytic diatoms, and soil/water physicochemical parameters. Thirty genera, 148 species, and 26 subspecies were identified. The proportional matrices at each taxonomic level were highly similar (Mantel's r > 0.75, P 0.83, P < 0.0001), and no significant difference was found when sites were placed into bins of excellent, good, fair, or poor, based on quartile scoring, for each taxonomic level. Specific conductance, soil pH, soil and water total phosphorous, and water color were significantly related to site non-metric multidimensional scaling (NMDS) ordination scores at each taxonomic level. This study concludes that indices of biotic integrity, when developed using autecological indices, provide similar qualitative conditional information across taxonomic levels for isolated herbaceous wetlands. JF - EcoHealth AU - Lane, Charles R AD - H.T. Odum Center for Wetlands, Phelps Lab, University of Florida, P.O. Box 116350, Gainesville, FL, 32611-6350, USA, Lane.Charles@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 219 EP - 230 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 4 IS - 2 SN - 1612-9202, 1612-9202 KW - Ecology Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Conductance KW - Multidimensional scaling KW - Soil pH KW - Bacillariophyceae KW - Diatoms KW - Wetlands KW - Ordination KW - Land use KW - Color KW - D 04040:Ecosystem and Ecology Studies KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754881740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=EcoHealth&rft.atitle=Assessment+of+Isolated+Wetland+Condition+in+Florida+Using+Epiphytic+Diatoms+at+Genus%2C+Species%2C+and+Subspecies+Taxonomic+Resolution&rft.au=Lane%2C+Charles+R&rft.aulast=Lane&rft.aufirst=Charles&rft.date=2007-06-01&rft.volume=4&rft.issue=2&rft.spage=219&rft.isbn=&rft.btitle=&rft.title=EcoHealth&rft.issn=16129202&rft_id=info:doi/10.1007%2Fs10393-007-0098-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Conductance; Soil pH; Multidimensional scaling; Diatoms; Wetlands; Ordination; Land use; Color; Bacillariophyceae DO - http://dx.doi.org/10.1007/s10393-007-0098-0 ER - TY - JOUR T1 - Identifying childhood age groups for exposure assessments and monitoring. AN - 70727248; 17640217 AB - The purpose of this article is to describe a standard set of age groups for exposure assessors to consider when assessing childhood exposure and potential dose to environmental contaminants. In addition, this article presents examples to show how the age groups can be applied in children's exposure assessments. A consistent set of childhood age groups, supported by an underlying scientific rationale, will improve the accuracy and comparability of exposure and risk assessments for children. The effort was undertaken in part to aid the U.S. Environmental Protection Agency (EPA) in implementing such regulatory initiatives as the 1997 Presidential Executive Order 13,045, which required all federal agencies to ensure that their standards take into account special risks to children. The standard age groups include: birth to <1 month; 1 to <3 months; 3 to <6 months; 6 to <12 months; 1 to <2 years; 2 to <3 years; 3 to <6 years; 6 to <11 years; 11 to <16 years; and 16 to <21 years. These age groups reflect a consideration of developmental changes in various behavioral, anatomical, and physiological characteristics that impact exposure and potential dose. It is expected that the availability of a standard set of early-life age groups will inform future analyses of exposure factors data as well as guide new research and data collection efforts to fill knowledge gaps. JF - Risk analysis : an official publication of the Society for Risk Analysis AU - Firestone, Michael AU - Moya, Jacqueline AU - Cohen-Hubal, Elaine AU - Zartarian, Valerie AU - Xue, Jianping AD - U.S. Environmental Protection Agency, Office of Children's Health Protection, 1200 Pennsylvania Ave. NW, Washington, DC 20460, USA. Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 701 EP - 714 VL - 27 IS - 3 SN - 0272-4332, 0272-4332 KW - Soil KW - 0 KW - Index Medicus KW - United States KW - Age Factors KW - United States Environmental Protection Agency KW - Child Behavior KW - Humans KW - Infant, Newborn KW - Models, Statistical KW - Child KW - Child, Preschool KW - Infant KW - Adult KW - Environmental Exposure KW - Diet KW - Adolescent KW - Male KW - Female KW - Risk Assessment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70727248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.atitle=Identifying+childhood+age+groups+for+exposure+assessments+and+monitoring.&rft.au=Firestone%2C+Michael%3BMoya%2C+Jacqueline%3BCohen-Hubal%2C+Elaine%3BZartarian%2C+Valerie%3BXue%2C+Jianping&rft.aulast=Firestone&rft.aufirst=Michael&rft.date=2007-06-01&rft.volume=27&rft.issue=3&rft.spage=701&rft.isbn=&rft.btitle=&rft.title=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.issn=02724332&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-14 N1 - Date created - 2007-07-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Trichloroethylene removal from groundwater in flow-through columns simulating a permeable reactive barrier constructed with plant mulch. AN - 70698642; 17612193 AB - Groundwater contaminated with TCE is commonly treated with a permeable reactive barrier (PRB) constructed with zero-valence iron. The cost of iron has driven a search for less costly alternatives, and composted plant mulch has been used as an alternative at several sites. A column study was conducted that simulated conditions in a PRB at Altus Air Force Base, Oklahoma. The reactive matrix was 50% (v/v) shredded tree mulch, 10% cotton gin trash, and 40% sand. The mean residence time of groundwater in the columns was 17 days. The estimated retardation factor for TCE was 12. TCE was supplied at concentrations near 20 microM. Over 793 days of operation, concentrations of TCE in the column effluents varied from 0.1% to 2% of the column influents. Concentrations of cis-DCE, vinyl chloride, ethylene, ethane, and acetylene could account for 1% of the TCE that was removed; however, up to 56% of 13C added as [1,2-13C] TCE in the column influents was recovered as 13C in carbon dioxide. After 383 and 793 d of operation, approximately one-half of the TCE removal was associated with abiotic reactions with FeS that accumulated in the reactive matrix. JF - Environmental science & technology AU - Shen, Hai AU - Wilson, John T AD - Office of Research and Development, U.S. Environmental Protection Agency, Robert S. Kerr Environmental Research Center, 919 Kerr Research Drive, Ada, Oklahoma 74820, USA. Hai.Shen@state.nm.us Y1 - 2007/06/01/ PY - 2007 DA - 2007 Jun 01 SP - 4077 EP - 4083 VL - 41 IS - 11 SN - 0013-936X, 0013-936X KW - Sulfides KW - 0 KW - Water Pollutants, Chemical KW - Trichloroethylene KW - 290YE8AR51 KW - Iron KW - E1UOL152H7 KW - Index Medicus KW - Bacteria -- metabolism KW - Permeability KW - Filtration KW - Iron -- analysis KW - Sulfides -- analysis KW - Sulfides -- chemistry KW - Iron -- chemistry KW - Adsorption KW - Biodegradation, Environmental KW - Trichloroethylene -- metabolism KW - Trichloroethylene -- chemistry KW - Water Pollutants, Chemical -- chemistry KW - Plants KW - Water Purification -- methods KW - Water Pollutants, Chemical -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70698642?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Trichloroethylene+removal+from+groundwater+in+flow-through+columns+simulating+a+permeable+reactive+barrier+constructed+with+plant+mulch.&rft.au=Shen%2C+Hai%3BWilson%2C+John+T&rft.aulast=Shen&rft.aufirst=Hai&rft.date=2007-06-01&rft.volume=41&rft.issue=11&rft.spage=4077&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-03 N1 - Date created - 2007-07-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Iron optimization for Fenton-driven oxidation of MTBE-spent granular activated carbon. AN - 70688797; 17612195 AB - Fenton-driven chemical oxidation of methyl tert-butyl ether (MTBE)-spent granular activated carbon (GAC) was accomplished through the addition of iron (Fe) and hydrogen peroxide (H2O2) (15.9 g/L; pH 3). The Fe concentration in GAC was incrementally varied (1020-25 660 mg/kg) by the addition of increasing concentrations of Fe solution (FeSO4-7H2O). MTBE degradation in Fe-amended GAC increased by an order of magnitude over Fe-unamended GAC and H2O2 reaction was predominantly (99%) attributed to GAC-bound Fe within the porous structure of the GAC. Imaging and microanalysis of GAC particles indicated limited penetration of Fe into GAC. The optimal Fe concentration was 6710 mg/kg (1020 mg/kg background; 5690 mg/kg amended Fe) and resulted in the greatest MTBE removal and maximum Fe loading oxidation efficiency (MTBE oxidized (microg)/ Fe loaded to GAC (mg/Kg)). At lower Fe concentrations, the H2O2 reaction was Fe limited. At higher Fe concentrations, the H2O2 reaction was not entirely Fe limited, and reductions in GAC surface area, GAC pore volume, MTBE adsorption, and Fe loading oxidation efficiency were measured. Results are consistent with nonuniform distribution of Fe, pore blockage in H2O2 transport, unavailable Fe, and limitations in H2O2 diffusive transport, and emphasize the importance of optimal Fe loading. JF - Environmental science & technology AU - Huling, Scott G AU - Jones, Patrick K AU - Lee, Tony R AD - Office of Research and Development, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, P.O. Box 1198, Ada, Oklahoma 74820, USA. huling.scott@epa.gov Y1 - 2007/06/01/ PY - 2007 DA - 2007 Jun 01 SP - 4090 EP - 4096 VL - 41 IS - 11 SN - 0013-936X, 0013-936X KW - Fenton's reagent KW - 0 KW - Methyl Ethers KW - Water Pollutants, Chemical KW - methyl tert-butyl ether KW - 29I4YB3S89 KW - Carbon KW - 7440-44-0 KW - Hydrogen Peroxide KW - BBX060AN9V KW - Iron KW - E1UOL152H7 KW - Index Medicus KW - Oxidation-Reduction KW - Solubility KW - Adsorption KW - Water Pollutants, Chemical -- chemistry KW - Iron -- chemistry KW - Water Purification -- methods KW - Carbon -- chemistry KW - Methyl Ethers -- chemistry KW - Hydrogen Peroxide -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70688797?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Iron+optimization+for+Fenton-driven+oxidation+of+MTBE-spent+granular+activated+carbon.&rft.au=Huling%2C+Scott+G%3BJones%2C+Patrick+K%3BLee%2C+Tony+R&rft.aulast=Huling&rft.aufirst=Scott&rft.date=2007-06-01&rft.volume=41&rft.issue=11&rft.spage=4090&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-03 N1 - Date created - 2007-07-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Perchlorate behavior in a municipal lake following fireworks displays. AN - 70688747; 17612176 AB - Perchlorate salts of potassium and ammonium are the primary oxidants in pyrotechnic mixtures, yet insufficient information is available regarding the relationship between fireworks displays and the environmental occurrence of perchlorate. Here we document changes in perchlorate concentrations in surface water adjacent to a site of fireworks displays from 2004 to 2006. Preceding fireworks displays, perchlorate concentrations in surface water ranged from 0.005 to 0.081 microg/L, with a mean value of 0.043 microg/L. Within 14 h after the fireworks, perchlorate concentrations spiked to values ranging from 24 to 1028x the mean baseline value. A maximum perchlorate concentration of 44.2 microg/L was determined following the July 4th event in 2006. After the fireworks displays, perchlorate concentrations decreased toward the background level within 20 to 80 days, with the rate of attenuation correlating to surface water temperature. Adsorption tests indicate that sediments underlying the water column have limited (< 100 nmol/g) capacity to remove perchlorate via chemical adsorption. Microcosms showed comparatively rapid intrinsic perchlorate degradation in the absence of nitrate consistent with the observed disappearance of perchlorate from the study site. This suggests that at sites with appropriate biogeochemical conditions, natural attenuation may be an important factor affecting the fate of perchlorate following fireworks displays. JF - Environmental science & technology AU - Wilkin, Richard T AU - Fine, Dennis D AU - Burnett, Nicole G AD - Office of Research and Development, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, 919 Kerr Research Drive, Ada, Oklahoma 74820, USA. wilkin.rick@epa.gov Y1 - 2007/06/01/ PY - 2007 DA - 2007 Jun 01 SP - 3966 EP - 3971 VL - 41 IS - 11 SN - 0013-936X, 0013-936X KW - Oxygen Isotopes KW - 0 KW - Perchlorates KW - Water Pollutants KW - Deuterium KW - AR09D82C7G KW - perchlorate KW - VLA4NZX2P4 KW - Index Medicus KW - Environmental Monitoring KW - Seasons KW - Adsorption KW - Time Factors KW - Water Pollutants -- chemistry KW - Water Pollutants -- analysis KW - Fresh Water -- chemistry KW - Perchlorates -- chemistry KW - Perchlorates -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70688747?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Perchlorate+behavior+in+a+municipal+lake+following+fireworks+displays.&rft.au=Wilkin%2C+Richard+T%3BFine%2C+Dennis+D%3BBurnett%2C+Nicole+G&rft.aulast=Wilkin&rft.aufirst=Richard&rft.date=2007-06-01&rft.volume=41&rft.issue=11&rft.spage=3966&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-03 N1 - Date created - 2007-07-06 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Environ Sci Technol. 2007 Jun 1;41(11):3792-3 [17612149] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Contributions of toluene and alpha-pinene to SOA formed in an irradiated toluene/alpha-pinene/NO(x)/ air mixture: comparison of results using 14C content and SOA organic tracer methods. AN - 70683242; 17612177 AB - An organic tracer method, recently proposed for estimating individual contributions of toluene and alpha-pinene to secondary organic aerosol (SOA) formation, was evaluated by conducting a laboratory study where a binary hydrocarbon mixture, containing the anthropogenic aromatic hydrocarbon, toluene, and the biogenic monoterpene, alpha-pinene, was irradiated in air in the presence of NO(x) to form SOA. The contributions of toluene and alpha-pinene to the total SOA concentration, calculated using the organic tracer method, were compared with those obtained with a more direct 14C content method. In the study, SOA to SOC ratios of 2.07 +/- 0.08 and 1.41 +/- 0.04 were measured for toluene and (alpha-pinene SOA, respectively. The individual tracer-based SOA contributions of 156 microg m(-3) for toluene and 198 microg m(-)3 for alpha-pinene, which together accounted for 82% of the gravimetrically determined total SOA concentration, compared well with the 14C values of 182 and 230 microg m(-3) measured for the respective SOA precursors. While there are uncertainties associated with the organic tracer method, largely due to the chemical complexity of SOA forming chemical mechanisms, the results of this study suggest the organic tracer method may serve as a useful tool for determining whether a precursor hydrocarbon is a major SOA contributor. JF - Environmental science & technology AU - Offenberg, John H AU - Lewis, Charles W AU - Lewandowski, Michael AU - Jaoui, Mohammed AU - Kleindienst, Tadeusz E AU - Edney, Edward O AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27511, USA. offenber.john@epa.gov Y1 - 2007/06/01/ PY - 2007 DA - 2007 Jun 01 SP - 3972 EP - 3976 VL - 41 IS - 11 SN - 0013-936X, 0013-936X KW - Aerosols KW - 0 KW - Air Pollutants KW - Carbon Radioisotopes KW - Monoterpenes KW - Particulate Matter KW - Nitric Oxide KW - 31C4KY9ESH KW - Toluene KW - 3FPU23BG52 KW - alpha-pinene KW - JPF3YI7O34 KW - Index Medicus KW - Aerosols -- analysis KW - Aerosols -- radiation effects KW - Particle Size KW - Aerosols -- chemistry KW - Monoterpenes -- chemistry KW - Toluene -- chemistry KW - Monoterpenes -- analysis KW - Toluene -- radiation effects KW - Air Pollutants -- analysis KW - Particulate Matter -- analysis KW - Particulate Matter -- chemistry KW - Air Pollutants -- radiation effects KW - Monoterpenes -- radiation effects KW - Nitric Oxide -- radiation effects KW - Nitric Oxide -- chemistry KW - Particulate Matter -- radiation effects KW - Toluene -- analysis KW - Air Pollutants -- chemistry KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70683242?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Contributions+of+toluene+and+alpha-pinene+to+SOA+formed+in+an+irradiated+toluene%2Falpha-pinene%2FNO%28x%29%2F+air+mixture%3A+comparison+of+results+using+14C+content+and+SOA+organic+tracer+methods.&rft.au=Offenberg%2C+John+H%3BLewis%2C+Charles+W%3BLewandowski%2C+Michael%3BJaoui%2C+Mohammed%3BKleindienst%2C+Tadeusz+E%3BEdney%2C+Edward+O&rft.aulast=Offenberg&rft.aufirst=John&rft.date=2007-06-01&rft.volume=41&rft.issue=11&rft.spage=3972&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-03 N1 - Date created - 2007-07-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A comparison of the monetized impact of IQ decrements from mercury emissions. AN - 70650216; 17589589 AB - The U.S. Environmental Protection Agency (EPA) reports that the upper bound of benefits from removing mercury emissions by U.S. power plants after implementing its Clean Air Interstate Rule (CAIR) is $210 million per year. In contrast, Trasande et al. [Environ Health Perspect 113:590-596 (2005)] estimated that American power plants impose an economic cost of $1.3 billion due to mercury emissions. It is impossible to directly compare these two estimates for a number of reasons, but we are able to compare the assumptions used and how they affect the results. We use Trasande's linear model with a cord/maternal blood ratio of 1.7 and calculate health effects to children whose mothers had blood mercury levels >/= 4.84 microg/L. We introduce the assumptions that the U.S. EPA used in its Clean Air Mercury Rule (CAMR) analysis and discuss the implications. Using this approach, it is possible to illustrate why the U.S. EPA assumptions produce a lower estimate. The introduction of all the U.S. EPA assumptions, except for those related to discounting, decreases the estimated monetized impact of global anthropogenic mercury emissions in the Trasande model by 81%. These assumptions also decrease the estimated impact of U.S. sources (including power plants) by almost 97%. When discounting is included, the U.S. EPA assumptions decrease Trasande's monetized estimate of global impacts by 88% and the impact of U.S. power plants by 98%. JF - Environmental health perspectives AU - Griffiths, Charles AU - McGartland, Al AU - Miller, Maggie AD - U.S. Environmental Protection Agency, Washington, DC 20004-2403, USA. griffiths.charles@epa.gov Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 841 EP - 847 VL - 115 IS - 6 SN - 0091-6765, 0091-6765 KW - Coal KW - 0 KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - United States KW - United States Environmental Protection Agency KW - Dose-Response Relationship, Drug KW - Humans KW - Child KW - Female KW - Pregnancy KW - Environment KW - Intelligence -- drug effects KW - Air Pollution -- adverse effects KW - Power Plants KW - Mercury -- economics KW - Mercury -- toxicity KW - Air Pollution -- economics KW - Prenatal Exposure Delayed Effects KW - Models, Theoretical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70650216?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=A+comparison+of+the+monetized+impact+of+IQ+decrements+from+mercury+emissions.&rft.au=Griffiths%2C+Charles%3BMcGartland%2C+Al%3BMiller%2C+Maggie&rft.aulast=Griffiths&rft.aufirst=Charles&rft.date=2007-06-01&rft.volume=115&rft.issue=6&rft.spage=841&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-06 N1 - Date created - 2007-06-25 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Ann N Y Acad Sci. 2006 Sep;1076:911-23 [17119266] Environ Res. 1995 Jul;70(1):1-6 [8603652] Natl Vital Stat Rep. 2002 Dec 19;51(3):1-38 [12583542] Lancet. 2003 May 17;361(9370):1686-92 [12767734] Environ Health Perspect. 2004 Apr;112(5):562-70 [15064162] Environ Res. 2004 Jul;95(3):385-93 [15220072] Environ Health Perspect. 2005 May;113(5):590-6 [15866768] Neurotoxicol Teratol. 1997 Nov-Dec;19(6):417-28 [9392777] JAMA. 1998 Aug 26;280(8):701-7 [9728641] Risk Anal. 1998 Dec;18(6):701-13 [9972579] Epidemiology. 1999 Sep;10(5):573-84 [10468437] Regul Toxicol Pharmacol. 2004 Dec;40(3):272-80 [15546681] Comment In: Environ Health Perspect. 2007 Aug;115(8):A396-7; author reply A397-8 [17687420] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Ketoconazole in the fathead minnow (Pimephales promelas): reproductive toxicity and biological compensation. AN - 70623613; 17571688 AB - Ketoconazole (KTC) is a model pharmaceutical representing imidazole and triazole pesticides, which inhibit fungal growth through blocking a cytochrome P450 (CYP)-mediated step in ergosterol biosynthesis. Several of these fungicides have been shown to be reversible inhibitors of CYPs in vertebrates (primarily mammals), including CYP isoforms involved in the pathway that converts cholesterol to active sex steroids. In these studies, we assessed the effects of KTC on aspects of steroidogenesis and reproductive function in the fathead minnow (Pimephales promelas). Exposure of spawning adults to the fungicide for 21 d significantly decreased egg production at a water concentration as low as 25 microg/L. Despite evidence of reduced ex vivo testosterone production by gonads from KTC-exposed fathead minnows, circulating plasma concentrations of sex steroids (testosterone, 17beta-estradiol) were not affected. Exposure to KTC caused an increase in the gonadosomatic index in both sexes and, in males, the fungicide caused a marked proliferation of interstitial (Leydig) cells. In addition, mRNA transcripts for two key steroidogenic enzymes, cytochrome P450 side-chain cleavage (CYP11A) and cytochrome P450 c17alpha hydroxylase/17,20 lyase (CYP17), were elevated by exposure to KTC. Both the changes in transcript levels and proliferation of gonad tissue represent potential adaptive or compensatory responses to impaired steroidogenic capacity. Overall our data indicate that, although KTC does adversely affect steroidogenesis and reproduction in the fathead minnow, the fish can compensate to some degree to mitigate effects of the fungicide. This has important implications for the interpretation of data from tests with endocrine-active chemicals. JF - Environmental toxicology and chemistry AU - Ankley, Gerald T AU - Jensen, Kathleen M AU - Kahl, Michael D AU - Makynen, Elizabeth A AU - Blake, Lindsey S AU - Greene, Katie J AU - Johnson, Rodney D AU - Villeneuve, Daniel L AD - U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804, USA. ankley.gerald@epa.gov Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 1214 EP - 1223 VL - 26 IS - 6 SN - 0730-7268, 0730-7268 KW - Antifungal Agents KW - 0 KW - RNA, Messenger KW - Cytochrome P-450 Enzyme System KW - 9035-51-2 KW - Ketoconazole KW - R9400W927I KW - Index Medicus KW - Animals KW - Cytochrome P-450 Enzyme System -- genetics KW - Cyprinidae -- physiology KW - Adaptation, Physiological KW - RNA, Messenger -- genetics KW - Antifungal Agents -- toxicity KW - Ketoconazole -- toxicity KW - Reproduction -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70623613?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Ketoconazole+in+the+fathead+minnow+%28Pimephales+promelas%29%3A+reproductive+toxicity+and+biological+compensation.&rft.au=Ankley%2C+Gerald+T%3BJensen%2C+Kathleen+M%3BKahl%2C+Michael+D%3BMakynen%2C+Elizabeth+A%3BBlake%2C+Lindsey+S%3BGreene%2C+Katie+J%3BJohnson%2C+Rodney+D%3BVilleneuve%2C+Daniel+L&rft.aulast=Ankley&rft.aufirst=Gerald&rft.date=2007-06-01&rft.volume=26&rft.issue=6&rft.spage=1214&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-10 N1 - Date created - 2007-06-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Designing small molecules for biodegradability. AN - 70617430; 17530907 JF - Chemical reviews AU - Boethling, R S AU - Sommer, Elizabeth AU - DiFiore, David AD - US Environmental Protection Agency, Office of Pollution Prevention and Toxics 7406M, 1200 Pennsylvania Avenue, NW, Washington, DC 20460, USA. boethling.bob@epa.gov Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 2207 EP - 2227 VL - 107 IS - 6 SN - 0009-2665, 0009-2665 KW - Organic Chemicals KW - 0 KW - Index Medicus KW - Structure-Activity Relationship KW - Conservation of Natural Resources KW - Environmental Pollution -- prevention & control KW - Organic Chemicals -- chemistry KW - Organic Chemicals -- chemical synthesis KW - Biodegradation, Environmental UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70617430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemical+reviews&rft.atitle=Designing+small+molecules+for+biodegradability.&rft.au=Boethling%2C+R+S%3BSommer%2C+Elizabeth%3BDiFiore%2C+David&rft.aulast=Boethling&rft.aufirst=R&rft.date=2007-06-01&rft.volume=107&rft.issue=6&rft.spage=2207&rft.isbn=&rft.btitle=&rft.title=Chemical+reviews&rft.issn=00092665&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-30 N1 - Date created - 2007-06-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Decline in pesticide poisonings in the United States from 1995 to 2004. AN - 70597792; 17558634 AB - Trends in rates of unintentional pesticide illnesses and injuries by type were estimated for the United States from 1995 to 2004. Poison Control Center data were examined for the years 1995 through 2004. Rates were calculated for pesticide type and selected pesticide classes based on estimated total United States population and proportion of population served. Pesticides as a proportion of poisonings to all substances over the years and vital statistics on deaths were examined to validate trends. Incidence rates of serious pesticide poisonings and injuries have declined 42% from 1995 to 2004 and death rates declined 62% over the same period. Selected, more toxic pesticides such as organophosphate and carbamate insecticides, strychnine rodenticides, and paraquat herbicides have shown greater declines, ranging 63% to 79%. Pesticide poisonings and injuries appear to have declined in the past decade. JF - Clinical toxicology (Philadelphia, Pa.) AU - Blondell, Jerome M AD - United States Environmental Protection Agency, Springfield, Virginia, USA. jblondell@cox.net PY - 2007 SP - 589 EP - 592 VL - 45 IS - 5 SN - 1556-3650, 1556-3650 KW - Carbamates KW - 0 KW - Pesticides KW - Strychnine KW - H9Y79VD43J KW - Paraquat KW - PLG39H7695 KW - Abridged Index Medicus KW - Index Medicus KW - Carbamates -- poisoning KW - Paraquat -- poisoning KW - Organophosphate Poisoning KW - Humans KW - Poisoning -- epidemiology KW - Strychnine -- poisoning KW - United States -- epidemiology KW - Poison Control Centers -- statistics & numerical data KW - Databases, Factual -- statistics & numerical data KW - Pesticides -- poisoning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70597792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.atitle=Decline+in+pesticide+poisonings+in+the+United+States+from+1995+to+2004.&rft.au=Blondell%2C+Jerome+M&rft.aulast=Blondell&rft.aufirst=Jerome&rft.date=2007-06-01&rft.volume=45&rft.issue=5&rft.spage=589&rft.isbn=&rft.btitle=&rft.title=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.issn=15563650&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-30 N1 - Date created - 2007-06-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Public health and economic impact of dampness and mold. AN - 70575459; 17542835 AB - The public health risk and economic impact of dampness and mold exposures was assessed using current asthma as a health endpoint. Individual risk of current asthma from exposure to dampness and mold in homes from W.J. Fisk, Q. Lei-Gomez & M.J. Mendell [(2007) Indoor Air, [corrected] 17, 284-296], and [corrected] asthma risks calculated from additional studies that reported the prevalence of dampness and mold in homes were used to estimate the proportion of US current asthma cases that are attributable to dampness and mold exposure at 21% (95% confidence internal 12-29%). An examination of the literature covering dampness and mold in schools, offices, and institutional buildings, which is summarized in the Appendix, suggests that risks from exposure in these buildings are similar to risks from exposures in homes. Of the 21.8 million people reported to have asthma in the USA, approximately 4.6 (2.7-6.3) million cases are estimated to be attributable to dampness and mold exposure in the home. Estimates of the national cost of asthma from two prior studies were updated to 2004 and used to estimate the economic impact of dampness and mold exposures. By applying the attributable fraction to the updated national annual cost of asthma, the national annual cost of asthma that is attributable to dampness and mold exposure in the home is estimated to be $3.5 billion ($2.1-4.8 billion). Analysis indicates that exposure to dampness and mold in buildings poses significant public health and economic risks in the USA. These findings are compatible with public policies and programs that help control moisture and mold in buildings. There is a need to control moisture in both new and existing construction because of the significant health consequences that can result from dampness and mold. This paper demonstrates that dampness and mold in buildings is a significant public health problem with substantial economic impact. JF - Indoor air AU - Mudarri, D AU - Fisk, W J AD - U.S. Environmental Protection Agency, Indoor Environments Division, Office of Radiation and Indoor Air, Washington, DC, USA. Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 226 EP - 235 VL - 17 IS - 3 SN - 0905-6947, 0905-6947 KW - Air Pollutants KW - 0 KW - Index Medicus KW - Schools KW - Humans KW - Workplace KW - United States -- epidemiology KW - Air Pollutants -- adverse effects KW - Public Health -- economics KW - Air Pollutants -- economics KW - Risk Assessment KW - Air Pollution, Indoor -- adverse effects KW - Respiratory Tract Diseases -- economics KW - Air Pollution, Indoor -- economics KW - Fungi KW - Respiratory Tract Diseases -- etiology KW - Environmental Exposure -- economics KW - Respiratory Tract Diseases -- epidemiology KW - Humidity KW - Environmental Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70575459?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Indoor+air&rft.atitle=Public+health+and+economic+impact+of+dampness+and+mold.&rft.au=Mudarri%2C+D%3BFisk%2C+W+J&rft.aulast=Mudarri&rft.aufirst=D&rft.date=2007-06-01&rft.volume=17&rft.issue=3&rft.spage=226&rft.isbn=&rft.btitle=&rft.title=Indoor+air&rft.issn=09056947&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-11-06 N1 - Date created - 2007-06-04 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: Indoor Air. 2007 Aug;17(4):334 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of storage, RNA extraction, genechip type, and donor sex on gene expression profiling of human whole blood. AN - 70510042; 17434907 AB - Gene expression profiling of whole blood may be useful for monitoring toxicological exposure and for diagnosis and monitoring of various diseases. Several methods are available that can be used to transport, store, and extract RNA from whole blood, but it is not clear which procedures alter results. In addition, characterization of interindividual and sex-based variation in gene expression is needed to understand sources and extent of variability. Whole blood was obtained from adult male and female volunteers (n = 42) and stored at various temperatures for various lengths of time. RNA was isolated and RNA quality analyzed. Affymetrix GeneChips (n = 23) were used to characterize gene expression profiles (GEPs) and to determine the effects on GEP of storage conditions, extraction techniques, types of GeneChip, or donor sex. Hierarchical clustering and principal component analysis were used to assess interindividual differences. Regression analysis was used to assess the relative impact of the studied variables. Storage of blood samples for >1 week at 4 degrees C diminished subsequent RNA quality. Interindividual GEP differences were seen, but larger effects were observed related to RNA extraction technique, GeneChip, and donor sex. The relative importance of the variables was as follows: storage < genechip < extraction technique < donor sex. Sample storage and extraction methods and interindividual differences, particularly donor sex, affect GEP of human whole blood. JF - Clinical chemistry AU - Kim, Sung Jae AU - Dix, David J AU - Thompson, Kary E AU - Murrell, Rachel N AU - Schmid, Judith E AU - Gallagher, Jane E AU - Rockett, John C AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 1038 EP - 1045 VL - 53 IS - 6 SN - 0009-9147, 0009-9147 KW - RNA KW - 63231-63-0 KW - Index Medicus KW - Sex Factors KW - Humans KW - Principal Component Analysis KW - Adult KW - Oligonucleotide Array Sequence Analysis -- instrumentation KW - Cluster Analysis KW - Male KW - Female KW - RNA -- blood KW - Gene Expression Profiling -- instrumentation KW - RNA -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70510042?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+chemistry&rft.atitle=Effects+of+storage%2C+RNA+extraction%2C+genechip+type%2C+and+donor+sex+on+gene+expression+profiling+of+human+whole+blood.&rft.au=Kim%2C+Sung+Jae%3BDix%2C+David+J%3BThompson%2C+Kary+E%3BMurrell%2C+Rachel+N%3BSchmid%2C+Judith+E%3BGallagher%2C+Jane+E%3BRockett%2C+John+C&rft.aulast=Kim&rft.aufirst=Sung&rft.date=2007-06-01&rft.volume=53&rft.issue=6&rft.spage=1038&rft.isbn=&rft.btitle=&rft.title=Clinical+chemistry&rft.issn=00099147&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-29 N1 - Date created - 2007-05-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity. AN - 70507845; 17383973 AB - Toxicogenomic analysis of five environmental chemicals was performed to investigate the ability of genomics to predict toxicity, categorize chemicals, and elucidate mechanisms of toxicity. Three triazole antifungals (myclobutanil, propiconazole, and triadimefon) and two perfluorinated chemicals [perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS)] were administered daily via oral gavage for one, three, or five consecutive days to male Sprague-Dawley rats at single doses of 300, 300, 175, 20, or 10 mg/kg/day, respectively. Clinical chemistry, hematology, and histopathology were measured at all time points. Gene expression profiling of livers from three rats per treatment group at all time points was performed on the CodeLink Uniset Rat I Expression array. Data were analyzed in the context of a large reference toxicogenomic database containing gene expression profiles for over 630 chemicals. Genomic signatures predicting hepatomegaly and hepatic injury preceded those results for all five chemicals, and further analysis segregated chemicals into two distinct classes. The triazoles caused similar gene expression changes as other azole antifungals, particularly the induction of pregnane X receptor (PXR)-regulated xenobiotic metabolism and oxidative stress genes. In contrast, PFOA and PFOS exhibited peroxisome proliferator-activated receptor alpha agonist-like effects on genes associated with fatty acid homeostasis. PFOA and PFOS also resulted in downregulation of cholesterol biosynthesis genes, matching an in vivo decrease in serum cholesterol, and perturbation of thyroid hormone metabolism genes matched by serum thyroid hormone depletion in vivo. The concordance of in vivo observations and gene expression findings demonstrated the ability of genomics to accurately categorize chemicals, identify toxic mechanisms of action, and predict subsequent pathological responses. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Martin, Matthew T AU - Brennan, Richard J AU - Hu, Wenyue AU - Ayanoglu, Eser AU - Lau, Christopher AU - Ren, Hongzu AU - Wood, Carmen R AU - Corton, J Christopher AU - Kavlock, Robert J AU - Dix, David J AD - National Center for Computational Toxicology, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 595 EP - 613 VL - 97 IS - 2 SN - 1096-6080, 1096-6080 KW - Biomarkers KW - 0 KW - Fluorocarbons KW - Fungicides, Industrial KW - Hormones KW - Thyroid Hormones KW - Triazoles KW - Testosterone KW - 3XMK78S47O KW - Index Medicus KW - Weight Gain -- drug effects KW - Animals KW - Oligonucleotide Array Sequence Analysis KW - Hormones -- blood KW - Reverse Transcriptase Polymerase Chain Reaction KW - Rats KW - Rats, Sprague-Dawley KW - Testosterone -- blood KW - Oxidative Stress -- drug effects KW - Thyroid Hormones -- blood KW - Male KW - Organ Size -- drug effects KW - Fluorocarbons -- pharmacokinetics KW - Liver -- pathology KW - Triazoles -- toxicity KW - Chemical and Drug Induced Liver Injury -- pathology KW - Fluorocarbons -- toxicity KW - Liver -- metabolism KW - Fungicides, Industrial -- toxicity KW - Triazoles -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70507845?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+Resources+Planning+and+Management&rft.atitle=Model+for+Estimating+Acute+Health+Impacts+from+Consumption+of+Contaminated+Drinking+Water&rft.au=Murray%2C+R%3BUber%2C+J%3BJanke%2C+R&rft.aulast=Murray&rft.aufirst=R&rft.date=2006-08-01&rft.volume=132&rft.issue=4&rft.spage=293&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+Resources+Planning+and+Management&rft.issn=07339496&rft_id=info:doi/10.1061%2F%28ASCE%290733-9496%282006%29132%3A4%28293%29 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-06 N1 - Date created - 2007-05-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - An observational study of 127 preschool children at their homes and daycare centers in Ohio: environmental pathways to cis- and trans-permethrin exposure. AN - 70473174; 17258193 AB - The potential exposures of 127 preschool children to the pyrethroid insecticides, cis- and trans-permethrin, in their everyday environments were examined. Participants were recruited randomly from 127 homes and 16 daycare centers in six Ohio (OH) counties. Monitoring was performed over a 48-h period at the children's homes and/or daycare centers. Samples collected included soil, carpet dust, indoor air, outdoor air, diet, hand wipes, surface wipes, transferable residues, and urine. The environmental samples were analyzed for the cis and trans isomers of permethrin, and the urine samples were analyzed for the pyrethroid urinary metabolite, 3-phenoxybenzoic acid (3-PBA), by gas chromatography/mass spectrometry. The isomers were detected most often in the dust (100%) and hand wipe (>78%) samples collected at both homes and daycare centers. The median levels of cis-permethrin (470 and 1010 ng/g) were higher than the median levels of trans-permethrin (344 and 544 ng/g) in the dust samples at both the children's homes and daycare centers, respectively. In the children's hand wipe samples, the median levels of cis- and trans-permethrin were similar, ranging from 0.03 to 0.04 ng/cm(2), at both locations. The urinary metabolite 3-PBA was detected in 67% of the children's urine samples. The median urinary 3-PBA concentration for the children was 0.3 ng/mL, and the maximum value for one child was 33.8 ng/mL. The primary route of the children's exposure to the combined isomers was through dietary ingestion, followed by indirect ingestion. In addition, our calculated aggregate absorbed doses of permethrin accounted for about 60% of the excreted amounts of 3-PBA found in the children's urine. In conclusion, these children were potentially exposed to low levels of permethrin from several sources, and through several pathways and routes. JF - Environmental research AU - Morgan, Marsha K AU - Sheldon, Linda S AU - Croghan, Carry W AU - Jones, Paul A AU - Chuang, Jane C AU - Wilson, Nancy K AD - National Exposure Research Laboratory, USEPA, 109 T.W. Alexander Dr., MD-E205-04, Research Triangle Park, NC 27713-4411, USA. morgan.marsha@epa.gov Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 266 EP - 274 VL - 104 IS - 2 SN - 0013-9351, 0013-9351 KW - Environmental Pollutants KW - 0 KW - Permethrin KW - 509F88P9SZ KW - Index Medicus KW - Environmental Monitoring KW - Humans KW - Ohio KW - Child, Preschool KW - Permethrin -- analysis KW - Air Pollution, Indoor -- analysis KW - Housing -- standards KW - Child Day Care Centers -- standards KW - Environmental Exposure -- analysis KW - Permethrin -- urine KW - Environmental Pollutants -- urine KW - Environmental Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70473174?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+research&rft.atitle=An+observational+study+of+127+preschool+children+at+their+homes+and+daycare+centers+in+Ohio%3A+environmental+pathways+to+cis-+and+trans-permethrin+exposure.&rft.au=Morgan%2C+Marsha+K%3BSheldon%2C+Linda+S%3BCroghan%2C+Carry+W%3BJones%2C+Paul+A%3BChuang%2C+Jane+C%3BWilson%2C+Nancy+K&rft.aulast=Morgan&rft.aufirst=Marsha&rft.date=2007-06-01&rft.volume=104&rft.issue=2&rft.spage=266&rft.isbn=&rft.btitle=&rft.title=Environmental+research&rft.issn=00139351&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-29 N1 - Date created - 2007-05-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Comparisons of polychromatic and monochromatic UV-based treatments of bisphenol-A in water via toxicity assessments. AN - 70440652; 17397900 AB - Polychromatic ultraviolet irradiation, such as from medium pressure (MP) Hg lamps may enhance the UV degradation of environmental pollutants as compared to low pressure (LP) Hg UV sources emitting monochromatic irradiation. Typically, studies involving destruction of environmental pollutants such as endocrine disrupting compounds (EDCs) are based on measurement of the parent compound decay using analytical chemistry, but such information is insufficient to determine an effective treatment endpoint because the identity and biological activity of many transformation products remain unknown. Bioanalytical methods to assess residual biological activity of a treated water offers one means to compare removal efficiency of EDC activity between MP- and LP-UV lamps under photolysis and UV/H2O2 oxidation. In this study, changes in estrogenic activity of bisphenol-A (BPA) as a function of UV treatment were evaluated using both an in vitro yeast estrogen screen and in vivo vitellogenin assay with Japanese medaka (Oryzias latipes) fish. Decay of BPA parent compound and formation of degradation products were followed using HPLC analysis. Results demonstrated that MP-UV direct photolysis more effectively removed BPA and associated estrogenic activity compared to LP-UV lamps. UV in combination with H2O2 significantly removed estrogenic activity in vitro and in vivo compared to direct photolysis; however, no significant difference in removal rates was found between the two lamps under UV/H2O2 oxidation. Furthermore, the UV/H2O2 process was effective for reducing embryo toxicity of BPA, but resulted in the production of acidic intermediates, causing acute toxicity and delayed hatching in some medaka embryos. JF - Chemosphere AU - Chen, Pei-Jen AU - Kullman, Seth W AU - Hinton, David E AU - Linden, Karl G AD - National Health and Environmental Effects Research Laboratory, EPA, RTP, NC, USA. Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 1041 EP - 1049 VL - 68 IS - 6 SN - 0045-6535, 0045-6535 KW - Benzhydryl Compounds KW - 0 KW - Endocrine Disruptors KW - Phenols KW - Hydrogen Peroxide KW - BBX060AN9V KW - bisphenol A KW - MLT3645I99 KW - Index Medicus KW - Oryzias KW - Animals KW - Oxidation-Reduction -- radiation effects KW - Photolysis -- radiation effects KW - Embryo, Nonmammalian -- drug effects KW - Endocrine Disruptors -- toxicity KW - Ultraviolet Rays KW - Phenols -- radiation effects KW - Endocrine Disruptors -- radiation effects KW - Waste Disposal, Fluid -- methods KW - Phenols -- toxicity KW - Endocrine Disruptors -- analysis KW - Phenols -- analysis KW - Hydrogen Peroxide -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70440652?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Comparisons+of+polychromatic+and+monochromatic+UV-based+treatments+of+bisphenol-A+in+water+via+toxicity+assessments.&rft.au=Chen%2C+Pei-Jen%3BKullman%2C+Seth+W%3BHinton%2C+David+E%3BLinden%2C+Karl+G&rft.aulast=Chen&rft.aufirst=Pei-Jen&rft.date=2007-06-01&rft.volume=68&rft.issue=6&rft.spage=1041&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-28 N1 - Date created - 2007-04-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Stalagmite evidence from Belize indicating significant droughts at the time of Preclassic Abandonment, the Maya Hiatus, and the Classic Maya collapse AN - 51393350; 2007-080210 AB - Paleoenvironmental data from a stalagmite from western Belize provide a 3300-year record of droughts that impacted the Maya civilization at least four times across a span of 1500 years, and the most sustained period of drought coincided with the collapse of Classic Maya civilization. The stalagmite, which comes from Macal Chasm in the Vaca Plateau, provides reliably dated reflectance, color, luminescence, and C and O stable isotope records for the period from 1225 B.C. to the present. The record thus encompasses the Maya Preclassic, Classic, and Postclassic periods. The Maya civilization peaked in population density and socioeconomic complexity during the Classic period extending from A.D. 25 to 900, but it declined abruptly over the years from A.D. 750 and 900. The stalagmite record indicates that a series of droughts, which collectively form the most prolonged dry interval in the 3300-year record, lasted from A.D. 700 to 1135 and thus coincided with the collapse of the Maya civilization. In addition, two earlier droughts evident in the stalagmite record coincided with the Preclassic Abandonment and the Maya Hiatus, two earlier declines in Maya civilization. A drought in the mid-1400s recorded in post-Classic documents is also evident in the stalagmite record. Collectively, these findings illustrate the dependence of Mayan civilization on water supplies and the impact of declining water resources on a vibrant civilization. JF - Palaeogeography, Palaeoclimatology, Palaeoecology AU - Webster, James W AU - Brook, George A AU - Railsback, L Bruce AU - Cheng, Hai AU - Edwards, R Lawrence AU - Alexander, Clark AU - Reeder, Philip P Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 1 EP - 17 PB - Elsevier, Amsterdam VL - 250 IS - 1-4 SN - 0031-0182, 0031-0182 KW - Belize KW - terrestrial environment KW - oxygen KW - X-ray diffraction data KW - isotopes KW - caves KW - Mayan period KW - paleoclimatology KW - Holocene KW - stable isotopes KW - uranium disequilibrium KW - paleoecology KW - human ecology KW - drought KW - Cenozoic KW - stalagmites KW - radioactive isotopes KW - dates KW - carbon KW - absolute age KW - geochemistry KW - Classic Maya period KW - speleothems KW - water supply KW - experimental studies KW - archaeology KW - Quaternary KW - isotope ratios KW - arid environment KW - C-13/C-12 KW - O-18/O-16 KW - Vaca Plateau KW - Late Classic Maya period KW - calcite KW - Macal Chasm KW - luminescence KW - optical properties KW - C-14 KW - upper Holocene KW - solution features KW - Preclassic Maya period KW - Central America KW - carbonates KW - 24:Quaternary geology KW - 03:Geochronology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51393350?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Palaeogeography%2C+Palaeoclimatology%2C+Palaeoecology&rft.atitle=Stalagmite+evidence+from+Belize+indicating+significant+droughts+at+the+time+of+Preclassic+Abandonment%2C+the+Maya+Hiatus%2C+and+the+Classic+Maya+collapse&rft.au=Webster%2C+James+W%3BBrook%2C+George+A%3BRailsback%2C+L+Bruce%3BCheng%2C+Hai%3BEdwards%2C+R+Lawrence%3BAlexander%2C+Clark%3BReeder%2C+Philip+P&rft.aulast=Webster&rft.aufirst=James&rft.date=2007-06-01&rft.volume=250&rft.issue=1-4&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Palaeogeography%2C+Palaeoclimatology%2C+Palaeoecology&rft.issn=00310182&rft_id=info:doi/10.1016%2Fj.palaeo.2007.02.022 L2 - http://www.sciencedirect.com/science/journal/00310182 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2007-01-01 N1 - Number of references - 45 N1 - Document feature - illus. incl. 2 tables, sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - PPPYAB N1 - SubjectsTermNotLitGenreText - absolute age; archaeology; arid environment; Belize; C-13/C-12; C-14; calcite; carbon; carbonates; caves; Cenozoic; Central America; Classic Maya period; dates; drought; experimental studies; geochemistry; Holocene; human ecology; isotope ratios; isotopes; Late Classic Maya period; luminescence; Macal Chasm; Mayan period; O-18/O-16; optical properties; oxygen; paleoclimatology; paleoecology; Preclassic Maya period; Quaternary; radioactive isotopes; solution features; speleothems; stable isotopes; stalagmites; terrestrial environment; upper Holocene; uranium disequilibrium; Vaca Plateau; water supply; X-ray diffraction data DO - http://dx.doi.org/10.1016/j.palaeo.2007.02.022 ER - TY - JOUR T1 - Multiobjective sensitivity analysis of sediment and nitrogen processes with a watershed model AN - 50657483; 2008-063760 JF - Water Resources Research AU - Arabi, Mazdak AU - Govindaraju, Rao S AU - Engel, Bernie AU - Hantush, Mohamed Y1 - 2007/06// PY - 2007 DA - June 2007 EP - W06409 PB - American Geophysical Union, Washington, DC VL - 43 IS - 6 SN - 0043-1397, 0043-1397 KW - United States KW - hydrology KW - numerical models KW - watersheds KW - Black Creek Watershed KW - nitrogen KW - nutrients KW - Dreisbach Watershed KW - transport KW - sensitivity analysis KW - Indiana KW - drainage basins KW - Midwest KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50657483?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Resources+Research&rft.atitle=Multiobjective+sensitivity+analysis+of+sediment+and+nitrogen+processes+with+a+watershed+model&rft.au=Arabi%2C+Mazdak%3BGovindaraju%2C+Rao+S%3BEngel%2C+Bernie%3BHantush%2C+Mohamed&rft.aulast=Arabi&rft.aufirst=Mazdak&rft.date=2007-06-01&rft.volume=43&rft.issue=6&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Water+Resources+Research&rft.issn=00431397&rft_id=info:doi/10.1029%2F2006WR005393 L2 - http://www.agu.org/journals/wr/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 33 N1 - PubXState - DC N1 - Document feature - illus. incl. 3 tables, sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - WRERAQ N1 - SubjectsTermNotLitGenreText - Black Creek Watershed; drainage basins; Dreisbach Watershed; hydrology; Indiana; Midwest; nitrogen; numerical models; nutrients; sensitivity analysis; transport; United States; watersheds DO - http://dx.doi.org/10.1029/2006WR005393 ER - TY - JOUR T1 - Privatization: property and the remaking of nature-society relations AN - 37048086; 3818364 JF - Antipode AU - Prudham, Scott AU - Bakker, Karen AU - Guthman, Julie AU - Mansfield, Becky AU - Robertson, Morgan AU - St Martin, Kevin AU - Wolford, Wendy AD - University of Toronto ; University of British Columbia ; University of California ; Ohio State University ; US Environmental Protection Agency ; Rutgers, The State University of New Jersey ; University of North Carolina, Chapel Hill Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 393 EP - 570 VL - 39 IS - 3 SN - 0066-4812, 0066-4812 KW - Anthropology KW - Sociology KW - Polanyi, Karl KW - Locke, John KW - New England KW - U.S.A. KW - Environment KW - Social justice KW - Ecosystems KW - Neoliberalism KW - Food KW - Economic development KW - Globalization KW - Property KW - Human geography KW - Fishing KW - Labelling KW - Fisheries KW - Water rights KW - Land rights KW - Capitalism KW - Activism KW - Indigenous populations KW - Protest movements KW - Equity KW - Community KW - Genetically modified organisms KW - Land reform KW - Patents KW - Privatization KW - Nature KW - Commodification KW - Government KW - Canada KW - Brazil KW - Alaska KW - Social movements KW - Governance KW - Fair trade KW - Biotechnology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37048086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antipode&rft.atitle=Privatization%3A+property+and+the+remaking+of+nature-society+relations&rft.au=Prudham%2C+Scott%3BBakker%2C+Karen%3BGuthman%2C+Julie%3BMansfield%2C+Becky%3BRobertson%2C+Morgan%3BSt+Martin%2C+Kevin%3BWolford%2C+Wendy&rft.aulast=Prudham&rft.aufirst=Scott&rft.date=2007-06-01&rft.volume=39&rft.issue=3&rft.spage=393&rft.isbn=&rft.btitle=&rft.title=Antipode&rft.issn=00664812&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Collection of 7 articles N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 10213; 10339; 6082 5475; 5459 5457 5460 1615 8573 11325; 2546 7805 3198 1077; 1626 12622; 9266; 5517 3893 3921 9653 11783; 551 9749; 13485 11032 9705; 11871 11869; 10367 9739; 4309; 8620 7371 9713 6203; 7083 2360 2688 2449 10404; 5114; 4735 12812; 11864 7032 9705; 6314 9846; 5009 5125 6431; 3907 3483 3921; 4044 3858 8560 9511 4309; 5549; 5551; 8578; 2012 4018 9713 6203; 4380; 5026; 2603; 7210 10691; 7213 10341 11032 9705; 75 293 14; 5 433 293 14; 63 386 14 ER - TY - JOUR T1 - Discovering price in all the wrong places: the work of commodity definition and price under neoliberal environmental policy AN - 37044827; 3818282 AB - Price plays a unique role in neoliberal economic theory, quantifying value and providing markets with the information needed to produce equilibrium conditions and optimal social welfare. While the role of price is clear, the mechanisms by which prices are discovered, and by which the commodities they value are defined, are left obscure in neoliberal theory. Automatic price discovery, and self-evident commodity identities, are assumed. Observation of newly created markets in ecosystem services suggests that this is a moment of significant tension within neoliberal practice, as potential market participants seek guidance from the state on appropriate commodity measures and pricing practices. Bureaucrats and economists, following the neoliberal preference for governance over government, turn the task back onto civil society. The invocation of abstract rules, instead of the formulation of practical guidance, by policymakers means that the neoliberal marketization of non-market public goods is a contingent and sometimes rudderless task for those who must make markets work on the ground. This presents many opportunities for constructive engagement on the part of geographers and other critics of neoliberal strategy. Reprinted by permission of Blackwell Publishers JF - Antipode AU - Robertson, Morgan AD - US Environmental Protection Agency Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 500 EP - 526 VL - 39 IS - 3 SN - 0066-4812, 0066-4812 KW - Economics KW - Political Science KW - Human geography KW - Community KW - Government KW - Ecosystems KW - Neoliberalism KW - Prices KW - Privatization KW - Property KW - Governance KW - Environmental policy KW - Nature UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37044827?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research&rft.atitle=Interannual+evolution+of+seasonal+thermohaline+properties+in+the+Gulf+of+Trieste+%28northern+Adriatic%29+1991-2003&rft.au=Malacic%2C+V%3BCelio%2C+M%3BCermelj%2C+B%3BBussani%2C+A%3BComici%2C+C&rft.aulast=Malacic&rft.aufirst=V&rft.date=2006-08-01&rft.volume=111&rft.issue=C8&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research&rft.issn=01480227&rft_id=info:doi/10.1029%2F2005JC003267 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 10213; 10339; 4336 5574 10472; 8620 7371 9713 6203; 10107; 4044 3858 8560 9511 4309; 2603; 5549; 5551; 8578; 6082 5475 ER - TY - JOUR T1 - Evaluation of aerial photography for predicting trends in structural attributes of Australian woodland including comparison with ground-based monitoring data AN - 36589519; 3384607 AB - The accurate assessment of trends in the woody structure of savannas has important implications for greenhouse accounting and land-use industries such as pastoralism. Two recent assessments of live woody biomass change from north-east Australian eucalypt woodland between the 1980s and 1990s present divergent results. The first estimate is derived from a network of permanent monitoring plots and the second from woody cover assessments from aerial photography. The differences between the studies are reviewed and include sample density, spatial scale and design. Further analyses targeting potential biases in the indirect aerial photography technique are conducted including a comparison of basal area estimates derived from 28 permanent monitoring sites with basal area estimates derived by the aerial photography technique. It is concluded that the effect of photo-scale; or the failure to include appropriate back-transformation of biomass estimates in the aerial photography study are not likely to have contributed significantly to the discrepancy. However, temporal changes in the structure of woodlands, for example, woodlands maturing from many smaller trees to fewer larger trees or seasonal changes, which affect the relationship between cover and basal area could impact on the detection of trends using the aerial photography technique. It is also possible that issues concerning photo-quality may bias assessments through time, and that the limited sample of the permanent monitoring network may inadequately represent change at regional scales. All rights reserved, Elsevier JF - Journal of environmental management AU - Fensham, Roderick J AU - Bray, S G AU - Fairfax, R J AD - Environmental Protection Agency, Australia Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 392 EP - 401 VL - 83 IS - 4 SN - 0301-4797, 0301-4797 KW - Economics KW - Woodland KW - Comparative analysis KW - Evaluation KW - Pastoralism KW - Australia KW - Monitoring KW - Structural change KW - Land use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36589519?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+management&rft.atitle=Evaluation+of+aerial+photography+for+predicting+trends+in+structural+attributes+of+Australian+woodland+including+comparison+with+ground-based+monitoring+data&rft.au=Fensham%2C+Roderick+J%3BBray%2C+S+G%3BFairfax%2C+R+J&rft.aulast=Fensham&rft.aufirst=Roderick&rft.date=2007-06-01&rft.volume=83&rft.issue=4&rft.spage=392&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+management&rft.issn=03014797&rft_id=info:doi/10.1016%2Fj.jenvman.2006.03.013 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 4551; 8247 6103 11032 9705; 9263 4811 827; 2630 971; 7217 7201 4025; 13649 7197 8560 9511 4309; 12321 6585 6590; 34 309 DO - http://dx.doi.org/10.1016/j.jenvman.2006.03.013 ER - TY - JOUR T1 - Influence of dosing volume on the neurotoxicity of bifenthrin AN - 20849731; 8253005 AB - Pyrethroids are pesticides with high insecticidal activity and relatively low potency in mammals. The influence of dosing volume on the neurobehavioral syndrome following oral acute exposure to the Type-I pyrethroid insecticide bifenthrin in corn oil was evaluated in adult male Long Evans rats. We tested bifenthrin effects at 1 and 5 ml/kg, two commonly used dose volumes in toxicological studies. Two testing times (4 and 7 h) were used in motor activity and functional observational battery (FOB) assessments. Four to eight doses were examined at either dosing condition (up to 20 or 26 mg/kg, at 1 and 5 ml/kg, respectively). Acute oral bifenthrin exposure produced toxic signs typical of Type I pyrethroids, with dose-related increases in fine tremor, decreased motor activity and grip strength, and increased pawing, head shaking, click response, and body temperature. Bifenthrin effects on motor activity and pyrethroid-specific clinical signs were arrow up -fold more potent at 1 ml/kg than 5 ml/kg. This difference was clearly evident at 4 h and slightly attenuated at 7 h post-dosing. Benchmark dose (BMD) modeling estimated similar 2-fold potency differences in motor activity and pyrethroid-specific FOB data. These findings demonstrate that dose volume, in studies using corn oil as the vehicle influences bifenthrin potency. Further, these data suggest that inconsistent estimates of pyrethroid potency between laboratories are at least partially due to differences in dosing volume. JF - Neurotoxicology and Teratology AU - Wolansky, MJ AU - McDaniel, K L AU - Moser, V C AU - Crofton, K M AD - MD-B105-04, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, United States, crofton.kevin@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 377 EP - 384 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 29 IS - 3 SN - 0892-0362, 0892-0362 KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Oil KW - Bone mineral density KW - Insecticides KW - Data processing KW - Head KW - Body temperature KW - Motor activity KW - Neurotoxicity KW - Pesticides KW - Pyrethroids KW - tremor KW - N3 11028:Neuropharmacology & toxicology KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20849731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Influence+of+dosing+volume+on+the+neurotoxicity+of+bifenthrin&rft.au=Wolansky%2C+MJ%3BMcDaniel%2C+K+L%3BMoser%2C+V+C%3BCrofton%2C+K+M&rft.aulast=Wolansky&rft.aufirst=MJ&rft.date=2007-06-01&rft.volume=29&rft.issue=3&rft.spage=377&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2007.01.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Oil; Data processing; Insecticides; Bone mineral density; Body temperature; Head; Motor activity; Pesticides; Neurotoxicity; tremor; Pyrethroids DO - http://dx.doi.org/10.1016/j.ntt.2007.01.007 ER - TY - JOUR T1 - Sensitization and tolerance with episodic (weekly) nicotine on motor activity in rats AN - 20849719; 8253001 AB - Nicotine's effects on motor activity have been studied extensively. Sensitization or tolerance can develop to nicotine's acute effects with daily exposure. Limited data indicate that sensitization can also develop when nicotine is given less frequently than daily. The present experiments were designed to extend this finding and to more fully characterize the effects of nicotine on motor activity when given at weekly intervals. In both experiments, the horizontal and vertical activity of adult female Long-Evans (LE) rats was recorded in photocell chambers. In Experiment 1, either saline or nicotine hydrogen tartrate (0.3, 0.6, 1.2 or 1.8 mg of salt/kg BW, s.c.) was administered once each week to rats that were tested daily (M-F). Acute nicotine administration produced no significant effect on horizontal activity at lower doses, while the highest dose produced a decrease (ca. 30%). Substantial and significant dose-related decreases in vertical activity were also obtained initially. Weekly dosing produced tolerance to nicotine's decreasing effects on vertical activity and increases (i.e., sensitization) in horizontal activity at all doses, and these effects persisted for at least 3 weeks. Experiment 2 partially replicated the results of Experiment 1 and indicated further that small sequential dose variations generally had little influence on nicotine tolerance and sensitization. The present results on horizontal activity extend prior findings of sensitization to weekly nicotine to include a broad range of doses. Results also showed that tolerance, but not sensitization, occurred to nicotine's effects on vertical activity over a comparable dose range. Further research is warranted on the importance of episodic, or recurring intermittent exposures in determining nicotine's effects, and those of other nicotinic agents, on behavior. JF - Neurotoxicology and Teratology AU - MacPhail, R C AU - Farmer, J D AU - Jarema, KA AD - B105-03, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA, macphail.robert@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 341 EP - 347 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 29 IS - 3 SN - 0892-0362, 0892-0362 KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Acute effects KW - Salts KW - Data processing KW - Nicotine KW - Motor activity KW - Hydrogen KW - X 24380:Social Poisons & Drug Abuse KW - N3 11028:Neuropharmacology & toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20849719?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Sensitization+and+tolerance+with+episodic+%28weekly%29+nicotine+on+motor+activity+in+rats&rft.au=MacPhail%2C+R+C%3BFarmer%2C+J+D%3BJarema%2C+KA&rft.aulast=MacPhail&rft.aufirst=R&rft.date=2007-06-01&rft.volume=29&rft.issue=3&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2006.11.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Acute effects; Salts; Data processing; Nicotine; Motor activity; Hydrogen DO - http://dx.doi.org/10.1016/j.ntt.2006.11.012 ER - TY - JOUR T1 - Reproductive functions and hypothalamic catecholamines in response to the soil fumigant metam sodium: Adaptations to extended exposures AN - 20849393; 8253004 AB - Metam sodium (MS) is a soil fumigant and Category II pesticide with a relatively low toxicity in mammals. Previous data have shown an ability to impair reproductive mechanisms in ovariectomized, estradiol-primed rats. A single i.p. injection blocked the luteinizing hormone (LH) surge that in gonadal-intact females initiates the final stages of follicular and oocytic maturation and serves as the trigger for ovulation. The effect paralleled a fall in hypothalamic norepinephrine (NE) and rise in hypothalamic dopamine (DA) that was likely due to a suppression in dopamine- beta -hydroxylase activity. In addition to determining the influence on catecholamine (CA) concentrations from a single oral exposure to MS, the present study explored effects of longer, 3-week treatments on estrous cyclicity, the LH surge, ovulation and hypothalamic CAs. Normally cycling 90 d S-D rats were administered MS (0-200 mg/kg/d, oral) and cyclicity was monitored daily. At the end of the 3rd week, proestrous blood was sampled over the afternoon from regular 4-day cyclers for a determination of LH. These animals were then killed on the following day of estrus (treatment days 21-26) for oocyte retrieval and assessment of hypothalamic CAs. Results showed that shortly after treatment began there occurred a dose-related period of persistent diestrus that typically lasted 8-16 d before regular cycles were reinstated. After 3 weeks, no effects were seen on the magnitude/timing of the LH surge or ovulated oocyte numbers. Anterior and posterior hypothalamic NE and DA were not significantly different from controls, although DA turnover (reflected by the ratio of DOPAC {3,4-dihydroxy-phenylacetic acid} to DA) in both anterior hypothalamic and caudate regions was decreased at all dosages. The data indicate that a 3 week oral exposure to MS induced an initial period of extended diestrus before the resumption of apparently normal reproductive activity, with previously reported CA alterations (apart from a persistent alteration in the DOPAC/DA ratio) being normalized by the end of dosing. JF - Neurotoxicology and Teratology AU - Goldman, J M AU - Cooper, R L AU - Murr, A S AD - Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States, goldman.jerome@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 368 EP - 376 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 29 IS - 3 SN - 0892-0362, 0892-0362 KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Hypothalamus KW - Adaptations KW - Data processing KW - Fumigants KW - Toxicity KW - Soil KW - Sodium KW - Blood KW - Estrus KW - Ovulation KW - Catecholamines KW - Dopamine KW - Luteinizing hormone KW - Pesticides KW - Norepinephrine KW - Oocytes KW - Ovariectomy KW - Estrus cycle KW - Menopause KW - N3 11028:Neuropharmacology & toxicology KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20849393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Reproductive+functions+and+hypothalamic+catecholamines+in+response+to+the+soil+fumigant+metam+sodium%3A+Adaptations+to+extended+exposures&rft.au=Goldman%2C+J+M%3BCooper%2C+R+L%3BMurr%2C+A+S&rft.aulast=Goldman&rft.aufirst=J&rft.date=2007-06-01&rft.volume=29&rft.issue=3&rft.spage=368&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2006.11.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Hypothalamus; Data processing; Adaptations; Fumigants; Toxicity; Sodium; Soil; Blood; Dopamine; Catecholamines; Ovulation; Estrus; Luteinizing hormone; Norepinephrine; Pesticides; Oocytes; Ovariectomy; Menopause; Estrus cycle DO - http://dx.doi.org/10.1016/j.ntt.2006.11.011 ER - TY - JOUR T1 - Developmental lead (Pb) exposure reduces the ability of the NMDA antagonist MK-801 to suppress long-term potentiation (LTP) in the rat dentate gyrus, in vivo AN - 20849013; 8253006 AB - Chronic developmental lead (Pb) exposure increases the threshold and enhances decay of long-term potentiation (LTP) in the dentate gyrus of the hippocampal formation. MK-801 and other antagonists of the N-methyl-d-aspartate (NMDA) glutamate receptor subtype impair induction of LTP. In addition, Pb exposure reduces presynaptic glutamate release and is associated with alterations in NMDA receptor expression. This study examined LTP in Pb-exposed animals challenged with a low dose of MK-801 to assess the sensitivity of this receptor to inhibition. Pregnant rats received 0.2% Pb acetate in the drinking water beginning on gestational day 16, and this regimen was continued through lactation. Adult male offspring maintained on this solution from weaning were prepared with indwelling electrodes in the perforant path and dentate gyrus. Several weeks later, input/output (I/O) functions were collected in awake animals before and after saline or MK-801 administration (0.05 mg/kg, s.c.). LTP was induced using suprathreshold train stimuli 60 min post-drug. Post-train I/O functions were reassessed 1 and 24 h after train delivery. Upon full decay of any induced LTP, drug conditions were reversed such that each animal was tested under saline and MK-801. I/O functions measured 1 and 24 h after train induction as well as immediate post-train responses revealed significant LTP of comparable magnitude that was induced in both control and Pb-exposed animals tested under saline conditions. In contrast, MK-801 reduced LTP in control but not in Pb-exposed animals. The broadening of the excitatory postsynaptic potential evident in responses evoked by train stimuli is NMDA-dependent. Pb exposure attenuated the MK-801-induced reduction in area of this NMDA component by ~50%. These findings are consistent with other neurochemical and behavioural observations and suggest that up-regulation of postsynaptic NMDA receptors produces subsensitivity to the inhibitory effects of MK-801 on hippocampal LTP following chronic developmental Pb exposure. JF - Neurotoxicology and Teratology AU - Gilbert, ME AU - Lasley, S M AD - U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, United States, gilbert.mary@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 385 EP - 393 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 29 IS - 3 SN - 0892-0362, 0892-0362 KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Excitatory postsynaptic potentials KW - N-Methyl-D-aspartic acid receptors KW - Hippocampus KW - Weaning KW - Acetic acid KW - Glutamic acid receptors KW - Dentate gyrus KW - Glutamic acid receptors (ionotropic) KW - MK-801 KW - Lead KW - Pregnancy KW - Lactation KW - Electrodes KW - Long-term potentiation KW - Perforant paths KW - Progeny KW - Drinking water KW - Drugs KW - N3 11028:Neuropharmacology & toxicology KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20849013?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Developmental+lead+%28Pb%29+exposure+reduces+the+ability+of+the+NMDA+antagonist+MK-801+to+suppress+long-term+potentiation+%28LTP%29+in+the+rat+dentate+gyrus%2C+in+vivo&rft.au=Gilbert%2C+ME%3BLasley%2C+S+M&rft.aulast=Gilbert&rft.aufirst=ME&rft.date=2007-06-01&rft.volume=29&rft.issue=3&rft.spage=385&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2007.01.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Excitatory postsynaptic potentials; N-Methyl-D-aspartic acid receptors; Hippocampus; Weaning; Glutamic acid receptors; Acetic acid; Lead; MK-801; Glutamic acid receptors (ionotropic); Dentate gyrus; Lactation; Pregnancy; Electrodes; Long-term potentiation; Perforant paths; Progeny; Drinking water; Drugs DO - http://dx.doi.org/10.1016/j.ntt.2007.01.006 ER - TY - JOUR T1 - Long-Distance GM pollen movement of creeping bentgrass using modeled wind trajectory analysis AN - 20804198; 7455021 AB - The importance of understanding the role of atmospheric conditions in pollen dispersal has grown in recent years with increased field-testing of genetically modified (GM) crop plants. An atmospheric model was used to characterize wind trajectories at 10 m and 100 m above GM pollen source fields located within a 4452-ha "control" area north of Madras, Oregon, USA, designated by the Oregon Department of Agriculture (ODA). The area was used in 2003 for the growth of GM creeping bentgrass (Agrostis stolonifera) engineered to be resistant to glyphosate herbicide. The presence of the GM gene (CP4 EPSPS) provided a distinct selectable marker for pollen-mediated gene flow to sentinel and resident Agrostis spp. plants. Linkage of GM gene presence with wind flow characteristics over the "control" area became essential to understand the timing and processes leading to long-distance transport of this pollen. Wind trajectories showed a general pattern of northwest to southeast air movement. Trajectory travel distances calculated hourly from 06:00 hours to 15:00 hours during the 2003 pollination period (15 June-15 July) showed movement up to 15 km from the "control" area's center by the first hour. Maximum travel distances increased to 40 and 55 km after two and three hours from release, respectively. Calculated wind trajectory positions corresponded with observed long-distance pollen-mediated gene flow in the seedlings of sentinel and resident plants. The highest correlations were found during the late morning hours. Back-calculated wind trajectories from sentinel and resident locations with GM-gene-positive progeny suggested that most successful fertilizations occurred in the direction of prevailing winds during late June 2003. The occurrence of positive progeny from sentinel plants, upwind of the "control" area during this period, indicated the additional influence of local topography on pollen dispersal. JF - Ecological Applications AU - Van de Water, PK AU - Watrud, L S AU - Lee, E H AU - Burdick, C AU - King, G A AD - National Health and Environmental Effects Research Laboratory, Western Ecology Division, U.S. Environmental Protection Agency Office of Research and Development, 200 Southwest 35th Street, Corvallis, Oregon 97333 USA, P.VandeWater@comcast.net Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 1244 EP - 1256 VL - 17 IS - 4 SN - 1051-0761, 1051-0761 KW - Biotechnology and Bioengineering Abstracts; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts; Ecology Abstracts KW - Travel KW - Agriculture KW - Agrostis KW - Excitatory postsynaptic potentials KW - Agrostis stolonifera KW - Wind flow KW - Correlations KW - Pollen transport KW - Crops KW - Atmospheric models KW - Fertilization KW - Gene flow KW - Atmospheric conditions KW - Wind KW - Topography KW - Pollination KW - Herbicides KW - Pollen KW - Seedlings KW - Progeny KW - Dispersal KW - Glyphosate KW - W 30925:Genetic Engineering KW - M2 551.556:Wind Effects (551.556) KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20804198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Applications&rft.atitle=Long-Distance+GM+pollen+movement+of+creeping+bentgrass+using+modeled+wind+trajectory+analysis&rft.au=Van+de+Water%2C+PK%3BWatrud%2C+L+S%3BLee%2C+E+H%3BBurdick%2C+C%3BKing%2C+G+A&rft.aulast=Van+de+Water&rft.aufirst=PK&rft.date=2007-06-01&rft.volume=17&rft.issue=4&rft.spage=1568&rft.isbn=&rft.btitle=&rft.title=Global+Change+Biology&rft.issn=13541013&rft_id=info:doi/10.1111%2Fj.1365-2486.2006.01191.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Agriculture; Travel; Pollination; Excitatory postsynaptic potentials; Herbicides; Crops; Pollen; Fertilization; Gene flow; Progeny; Seedlings; Dispersal; Wind; Glyphosate; Atmospheric conditions; Topography; Wind flow; Correlations; Pollen transport; Atmospheric models; Agrostis; Agrostis stolonifera ER - TY - JOUR T1 - Settlement and Survival of the Oyster Crassostrea virginica on Created Oyster Reef Habitats in Chesapeake Bay AN - 20587766; 8004992 AB - Efforts to restore the Eastern oyster (Crassostrea virginica) reef habitats in Chesapeake Bay typically begin with the placement of hard substrata to form three-dimensional mounds on the seabed to serve as a base for oyster recruitment and growth. A shortage of oyster shell for creating large-scale reefs has led to widespread use of other materials such as Surf clamshell (Spisula solidissima), as a substitute for oyster shell. Oyster recruitment, survival, and growth were monitored on intertidal reefs constructed from oyster and Surf clamshell near Fisherman's Island, Virginia, U.S.A. and on a subtidal Surf clamshell reef in York River, Virginia, U.S.A. At the intertidal reefs, oyster larvae settlement occurred at similar levels on both substrate types throughout the monitoring period but higher levels of post-settlement mortality occurred on clamshell reefs. The oyster shell reef supported greater oyster growth and survival and offered the highest degree of structural complexity. On the subtidal clamshell reef, the quality of the substrate varied with reef elevation. Large shell fragments and intact valves were scattered around the reef base, whereas small, tightly packed shell fragments paved the crest and flank of the reef mound. Oysters were more abundant and larger at the base of this reef and less abundant and smaller on the reef crest. The availability of interstitial space and appropriate settlement surfaces is hypothesized to account for the observed differences in oyster abundance across the reef systems. Patterns observed emphasize the importance of appropriate substrate selection for restoration activities to enhance natural recovery where an underlying habitat structure is destroyed. JF - Restoration Ecology AU - Nestlerode, Janet A AU - Luckenbach, Mark W AU - O'Beirn, Francis X AD - Department of Biological Sciences, School of Marine Science, College of William and Mary, Virginia Institute of Marine Science, 1208 Greate Road, Gloucester Point, VA 23062, U.S.A., nestlerode.janet@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 273 EP - 283 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 15 IS - 2 SN - 1061-2971, 1061-2971 KW - Atlantic surfclam KW - Eastern oyster KW - Sustainability Science Abstracts; Ecology Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Reefs KW - Mortality KW - Oyster reefs KW - Spisula solidissima KW - Recruitment KW - Brackish KW - Survival KW - Habitat KW - ANW, USA, Chesapeake Bay KW - Islands KW - Substrate preferences KW - ANW, USA, Virginia, Fisherman's I. KW - Habitat improvement KW - Nature conservation KW - Marine molluscs KW - Crassostrea virginica KW - Shells KW - Mounds KW - Ocean floor KW - Q5 08523:Conservation, wildlife management and recreation KW - Q1 08463:Habitat community studies KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20587766?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Restoration+Ecology&rft.atitle=Settlement+and+Survival+of+the+Oyster+Crassostrea+virginica+on+Created+Oyster+Reef+Habitats+in+Chesapeake+Bay&rft.au=Nestlerode%2C+Janet+A%3BLuckenbach%2C+Mark+W%3BO%27Beirn%2C+Francis+X&rft.aulast=Nestlerode&rft.aufirst=Janet&rft.date=2007-06-01&rft.volume=15&rft.issue=2&rft.spage=273&rft.isbn=&rft.btitle=&rft.title=Restoration+Ecology&rft.issn=10612971&rft_id=info:doi/10.1111%2Fj.1526-100X.2007.00210.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Oyster reefs; Substrate preferences; Habitat improvement; Recruitment; Nature conservation; Marine molluscs; Ocean floor; Mortality; Reefs; Islands; Survival; Shells; Mounds; Habitat; Spisula solidissima; Crassostrea virginica; ANW, USA, Virginia, Fisherman's I.; ANW, USA, Chesapeake Bay; Brackish DO - http://dx.doi.org/10.1111/j.1526-100X.2007.00210.x ER - TY - JOUR T1 - Exclusion of rare taxa affects performance of the O/E index in bioassessments AN - 20399667; 7594991 AB - The contribution of rare taxa to bioassessments based on multispecies assemblages is the subject of continued debate. As a result, users of predictive models such as River InVertebrate Prediction and Classification System (RIVPACS) disagree on whether to exclude locally rare taxa from the O/E index, where O is the number of taxa observed in a sampled assemblage, and E is the number that would be expected if the site were in a minimally disturbed reference condition. We assessed how the bioassessment performance of O/E was affected by the exclusion of taxa with site-specific, model-predicted occurrence probabilities that did not exceed thresholds of P sub(T) = 0 super(+), 0.1, 0.2, -¦ , 0.7. We assessed O/E performance for each of 10 predictive models applied to a total of 5685 stream and lake samples from throughout the contiguous USA. For 5 of the 10 cases, the standard deviation (SD) of O/E across reference sites was reduced by at least 0.02 O/E units when locally rare and uncommon taxa were excluded (P sub(T) = 0.5) from O/E, as compared with all taxa being included (P sub(T) = 0 super(+)). These reductions in SD denote increases in precision of the O/E index. We also assessed the sensitivity of O/E, measured by the % of test sites (that is, sites independently assessed as not being in reference condition) that were declared to be outside the reference distribution of O/E scores. Five of our 10 cases showed increases in sensitivity of ?10% at P sub(T) = 0.5 as compared with P sub(T) = 0 super(+). All cases that did not show increases in sensitivity or precision also showed no decrease in either of these performance measures as P sub(T) increased. A comparison of observed occurrence frequencies of taxa at reference and test sites qualitatively explained the size of the O/E sensitivity response in all 10 cases. This result suggests that effects of rare-taxa exclusion are a direct consequence of these occurrence frequencies rather than of predictive-model structures. Thus, we predict that other assemblage-based bioassessment tools are likely to show improved sensitivity when rare taxa are excluded. JF - Journal of the North American Benthological Society AU - Van Sickle, J AU - Larsen, D P AU - Hawkins, C P AD - National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, 200 SW 35th St., Corvallis, Oregon 97333 USA Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 319 EP - 331 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 26 IS - 2 SN - 0887-3593, 0887-3593 KW - Ecology Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Rivers KW - Biological surveys KW - Classification systems KW - Rare species KW - Freshwater KW - Streams KW - Models KW - Methodology KW - USA KW - Lakes KW - Community composition KW - Standard deviation KW - Invertebrata KW - Zoobenthos KW - Q1 08382:Ecological techniques and apparatus KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20399667?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+North+American+Benthological+Society&rft.atitle=Exclusion+of+rare+taxa+affects+performance+of+the+O%2FE+index+in+bioassessments&rft.au=Van+Sickle%2C+J%3BLarsen%2C+D+P%3BHawkins%2C+C+P&rft.aulast=Van+Sickle&rft.aufirst=J&rft.date=2007-06-01&rft.volume=26&rft.issue=2&rft.spage=319&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+North+American+Benthological+Society&rft.issn=08873593&rft_id=info:doi/10.1899%2F0887-3593%282007%29262.0.CO%3B2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Classification systems; Biological surveys; Community composition; Rare species; Zoobenthos; Methodology; Rivers; Lakes; Standard deviation; Streams; Models; Invertebrata; USA; Freshwater DO - http://dx.doi.org/10.1899/0887-3593(2007)26[319:EORTAP]2.0.CO;2 ER - TY - JOUR T1 - PBTK Modeling Demonstrates Contribution of Dermal and Inhalation Exposure Components to End-Exhaled Breath Concentrations of Naphthalene AN - 20393241; 7457097 AB - BACKGROUND: Dermal and inhalation exposure to jet propulsion fuel 8 (JP-8) have been measured in a few occupational exposure studies. However, a quantitative understanding of the relationship between external exposures and end-exhaled air concentrations has not been described for occupational and environmental exposure scenarios. OBJECTIVE: Out goal was to construct a physiologically based toxicokinetic (PBTK) model that quantitatively describes the relative contribution of dermal and inhalation exposures to the end-exhaled air concentrations of naphthalene among U.S. Air Force personnel. METHODS: The PBTK model comprised five compartments representing the stratum corneum, viable epidermis, blood, fat, and other tissues. The parameters were optimized using exclusively human exposure and biological monitoring data. RESULTS: The optimized values of parameters for naphthalene were a) permeability coefficient for the stratum corneum 6.8 x 10 super(-5) cm/hr, b) permeability coefficient for the viable epidermis 3.0 x 10 super(-3) cm/hr, c) fat: blood partition coefficient 25.6, and d) other tissue:blood partition coefficient 5.2. The skin permeability coefficient was comparable to the values estimated from in vitro studies. Based on simulations of workers' exposures to JP-8 during aircraft fuel-cell maintenance operations, the median relative contribution of dermal exposure to the end-exhaled breath concentration of naphthalene was 4% (10th percentile 1% and 90th percentile 11%). CONCLUSIONS: PBTK modeling allowed contributions of the end-exhaled air concentration of naphthalene to be partitioned between dermal and inhalation routes of exposure. Further study of inter- and intraindividual variations in exposure assessment is required to better characterize the toxicokinetic behavior of JP-8 components after occupational and/or environmental exposures. JF - Environmental Health Perspectives AU - Kim, D AU - Andersen, ME AU - Chao, Y-CE AU - Egeghy, P P AU - Rappaport, S M AU - Nylander-French, LA AD - National Exposure Research Laboratory, Human Exposure and Atmospheric Sciences Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA, leena_french@unc.edu Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 894 EP - 901 VL - 115 IS - 6 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts KW - Inhalation KW - Skin KW - Stratum corneum KW - Fuels KW - Simulation KW - Naphthalene KW - Maintenance KW - Models KW - Permeability KW - Blood KW - Epidermis KW - USA KW - Aircraft KW - Occupational exposure KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20393241?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=PBTK+Modeling+Demonstrates+Contribution+of+Dermal+and+Inhalation+Exposure+Components+to+End-Exhaled+Breath+Concentrations+of+Naphthalene&rft.au=Kim%2C+D%3BAndersen%2C+ME%3BChao%2C+Y-CE%3BEgeghy%2C+P+P%3BRappaport%2C+S+M%3BNylander-French%2C+LA&rft.aulast=Kim&rft.aufirst=D&rft.date=2007-06-01&rft.volume=115&rft.issue=6&rft.spage=894&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.9778 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Inhalation; Epidermis; Blood; Permeability; Skin; Aircraft; Stratum corneum; Fuels; Naphthalene; Occupational exposure; Models; Simulation; Maintenance; USA DO - http://dx.doi.org/10.1289/ehp.9778 ER - TY - JOUR T1 - Composition of PM sub(2) sub(.) sub(5) during the summer of 2003 in Research Triangle Park, North Carolina AN - 20354331; 7498625 AB - A field study was carried out during the summer of 2003 to examine the overall composition of fine particulate matter (PM sub(2) sub(.) sub(5)) in Research Triangle Park, North Carolina, USA, with particular emphasis on polar compounds from secondary organic aerosol (SOA). Collected samples were examined for gravimetric mass, organic and elemental carbon concentrations, inorganic ion concentrations, and detailed organic composition. On average, the ambient PM sub(2) sub(.) sub(5) was found to consist of 41% organic matter, 2% elemental carbon, 12% ammonium, 37% sulfate, and less than 1% nitrate and oxalate. Mass concentrations ranged from 6.4 to 31.4 mu gm super(-) super(3). The acidity of the aerosol was also estimated, and higher PM sub(2) sub(.) sub(5) and organic mass concentrations were generally observed under acidic conditions. A suite of chemical derivatization methods was used in conjunction with gas chromatography-mass spectrometry (GC-MS) to identify and quantify 29 polar organic compounds. Most of these compounds have been previously identified in laboratory photooxidation studies from hydrocarbon precursors, including isoprene, monoterpenes, beta -caryophyllene, and toluene. From laboratory studies, several of these polar compounds have been proposed as tracers for SOA, and concentrations measured in this study indicate the contributions of the precursor hydrocarbons to ambient SOA could be important. Some of the organic tracers, particularly those associated with isoprene SOA, represented a greater fraction of the organic carbon when the aerosol was acidic. JF - Atmospheric Environment AU - Lewandowski, M AU - Jaoui, M AU - Kleindienst, TE AU - Offenberg, J H AU - Edney, E O AD - US Environmental Protection Agency, RTP NC 27711, USA, lewandowski.michael@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 4073 EP - 4083 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 19 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Particle size KW - Sulfates KW - USA, North Carolina KW - Aerosols KW - Atmospheric pollution KW - Ion concentration KW - Nitrates KW - Organic matter KW - Toluene KW - Organic aerosols in atmosphere KW - Organic carbon KW - Particulates KW - Spectrometry KW - Tracers KW - Particulate matter in atmosphere KW - Carbon KW - Photooxidation KW - summer KW - Acidity KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20354331?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Composition+of+PM+sub%282%29+sub%28.%29+sub%285%29+during+the+summer+of+2003+in+Research+Triangle+Park%2C+North+Carolina&rft.au=Lewandowski%2C+M%3BJaoui%2C+M%3BKleindienst%2C+TE%3BOffenberg%2C+J+H%3BEdney%2C+E+O&rft.aulast=Lewandowski&rft.aufirst=M&rft.date=2007-06-01&rft.volume=41&rft.issue=19&rft.spage=4073&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.01.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Particulate matter in atmosphere; Ion concentration; Atmospheric pollution; Organic aerosols in atmosphere; Photooxidation; Spectrometry; Sulfates; Particle size; Aerosols; Nitrates; Toluene; Organic matter; Organic carbon; Particulates; Tracers; Carbon; summer; Acidity; USA, North Carolina DO - http://dx.doi.org/10.1016/j.atmosenv.2007.01.012 ER - TY - JOUR T1 - Field test of four methods for gas-phase ambient nitric acid AN - 20351377; 7499302 AB - Three semi-continuous methods for detecting nitric acid (HNO sub(3)) were tested against the annular denuder + filter pack (ADS) integrated collection technique at the Tampa Bay Regional Atmospheric Chemistry Experiment (BRACE) Sydney research station similar to 20km downwind of the Tampa, Florida, urban core. The semi-continuous instruments included: two slightly differing implementations of the NO sub(Y)-NO sub(Y) sub(@)u sub(*) (total oxides of nitrogen minus that total denuded of HNO sub(3)) denuder difference technique, one from the NOAA Air Resources Lab (ARL), and one from Atmospheric Research and Analysis, Inc. (ARA); the parallel plate wet diffusion scrubber + online ion chromatography technique from Texas Tech University (TTU); and the chemical ionization mass spectrometer from the Georgia Institute of Technology (GIT). Twelve hour ADS samples were collected by the University of South Florida (USF). Results for 10min samples computed from the various higher sampling frequencies of each semi-continuous instrument showed good agreement (R super(2)>0.7) for afternoon periods of the highest production and accumulation of HNO sub(3). Further, agreement was within +/-30% for these instruments even at HNO sub(3) concentrations 60% for the nighttime samples; ADS results were below the corporate mean maximum HNO sub(3) concentration by >30% as well. The four instruments using semi-continuous methods, by contrast, were all within 10% of each other's 12h mean mixing ratios. While only ARA employed a formal minimum detection limit at 0.050ppb, error analysis with the other techniques established that at the same level of precision, TTU's effective limit was approximately the same as ARA's and that ARL's limit was 0.030ppb; analysis for GIT showed no apparent effective limit at the levels of HNO sub(3) encountered in this field study. The importance of sample inlet height for HNO sub(3) measurements was indirectly shown through comparison to previous field work at this site when sample inlet heights ranged from 1.5-10m and produced systematic discrepancies in HNO sub(3) concentrations correlated with height of more than a factor of 2. JF - Atmospheric Environment AU - Arnold, J R AU - Hartsell, B E AU - Luke, W T AU - Rahmat Ullah, SM AU - Dasgupta, P K AU - Greg Huey, L AU - Tate, P AD - Air Resources Laboratory, National Oceanic and Atmospheric Administration, US Environmental Protection Agency, Office of Research and Development, 1200 6th Avenue/9th FL/OEA-095, Seattle, WA 98101-1128, USA, arnold.jeff@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 4210 EP - 4226 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 20 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Chromatography KW - ASW, USA, Florida, Tampa KW - Spectral analysis KW - Air pollution control KW - ASW, USA, Florida, Tampa Bay KW - Nitrogen oxides KW - Filters KW - ASW, USA, Georgia KW - PSE, Australia, New South Wales, Sydney KW - Scrubbers KW - Atmospheric chemistry KW - Nitric acid KW - Diffusion KW - Mixing ratio KW - Pollution control equipment KW - Meteorological observations KW - Ionization KW - Wind KW - Atmospheric research KW - Technology KW - P 0000:AIR POLLUTION KW - M2 551.501:Methods of Observation/Computations (551.501) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20351377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Field+test+of+four+methods+for+gas-phase+ambient+nitric+acid&rft.au=Arnold%2C+J+R%3BHartsell%2C+B+E%3BLuke%2C+W+T%3BRahmat+Ullah%2C+SM%3BDasgupta%2C+P+K%3BGreg+Huey%2C+L%3BTate%2C+P&rft.aulast=Arnold&rft.aufirst=J&rft.date=2007-06-01&rft.volume=41&rft.issue=20&rft.spage=4210&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2006.07.058 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Chromatography; Atmospheric chemistry; Spectral analysis; Mixing ratio; Meteorological observations; Ionization; Atmospheric research; Filters; Scrubbers; Nitric acid; Diffusion; Air pollution control; Pollution control equipment; Nitrogen oxides; Wind; Technology; ASW, USA, Georgia; PSE, Australia, New South Wales, Sydney; ASW, USA, Florida, Tampa; ASW, USA, Florida, Tampa Bay DO - http://dx.doi.org/10.1016/j.atmosenv.2006.07.058 ER - TY - JOUR T1 - A Classification of U.S. Estuaries Based on Physical and Hydrologic Attributes AN - 20200972; 7569091 AB - A classification of U.S. estuaries is presented based on estuarine characteristics that have been identified as important for quantifying stressor-response relationships in coastal systems. Estuaries within a class have similar physical and hydrologic characteristics and would be expected to demonstrate similar biological responses to stressor loads from the adjacent watersheds. Nine classes of estuaries were identified by applying cluster analysis to a database for 138 U.S. estuarine drainage areas. The database included physical measures of estuarine areas, depth and volume, as well as hydrologic parameters (i.e., tide height, tidal prism volume, freshwater inflow rates, salinity, and temperature). The ability of an estuary to dilute or flush pollutants can be estimated using physical and hydrologic properties such as volume, bathymetry, freshwater inflow and tidal exchange rates which influence residence time and affect pollutant loading rates. Thus, physical and hydrologic characteristics can be used to estimate the susceptibility of estuaries to pollutant effects. This classification of estuaries can be used by natural resource managers to describe and inventory coastal systems, understand stressor impacts, predict which systems are most sensitive to stressors, and manage and protect coastal resources. JF - Environmental Monitoring and Assessment AU - Engle, Virginia D AU - Kurtz, Janis C AU - Smith, Lisa M AU - Chancy, Cynthia AU - Bourgeois, Pete AD - U.S. Environmental Protection Agency, 1 Sabine Island Drive, Gulf Breeze, FL, 32561, USA, engle.virginia@epa.gov Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 397 EP - 412 PB - Springer-Verlag (Heidelberg), Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 129 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Pollution Abstracts; Ecology Abstracts; Meteorological & Geoastrophysical Abstracts; Aqualine Abstracts; Water Resources Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Residence time KW - Watersheds KW - Salinity KW - Tidal analysis KW - Classification KW - currency exchange rate KW - Environmental monitoring KW - Freshwater environments KW - Estuaries KW - Databases KW - bathymetry KW - Monitoring KW - Tidal exchange KW - Pollution effects KW - Natural Resources KW - Assessments KW - Pollutants KW - inflow KW - Brackishwater environment KW - coastal resources KW - Temperature effects KW - Drainage KW - Temperature KW - Bathymetry KW - Tides KW - Coastal zone management KW - Tide heights KW - USA KW - Natural resources KW - classification KW - D 04070:Pollution KW - SW 3010:Identification of pollutants KW - P 1000:MARINE POLLUTION KW - O 4080:Pollution - Control and Prevention KW - Q2 09261:General KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - M2 551.466:Ocean Waves and Tides (551.466) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20200972?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=A+Classification+of+U.S.+Estuaries+Based+on+Physical+and+Hydrologic+Attributes&rft.au=Engle%2C+Virginia+D%3BKurtz%2C+Janis+C%3BSmith%2C+Lisa+M%3BChancy%2C+Cynthia%3BBourgeois%2C+Pete&rft.aulast=Engle&rft.aufirst=Virginia&rft.date=2007-06-01&rft.volume=129&rft.issue=1-3&rft.spage=397&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-006-9372-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Pollutants; Classification; Residence time; Natural resources; Estuaries; Brackishwater environment; Bathymetry; Coastal zone management; Temperature effects; Databases; Freshwater environments; Drainage; Tide heights; Tidal exchange; Tidal analysis; Salinity; classification; Temperature; Pollution effects; inflow; currency exchange rate; bathymetry; Watersheds; Tides; coastal resources; Natural Resources; Assessments; Monitoring; USA DO - http://dx.doi.org/10.1007/s10661-006-9372-9 ER - TY - JOUR T1 - A preliminary exposure assessment of microcystins from consumption of drinking water in the United States AN - 19983090; 7500977 AB - This preliminary human exposure assessment of cyanotoxins from consumption of treated drinking water in the United States is based on reported concentrations of microcystin-LR equivalents, (herein referred to as MC-LR), a cyanotoxin measured in a study of North American drinking waters conducted by the American Water Works Association from June 1996 to January 1998. The sampling protocol resulted in a distribution of MC-LR concentrations in waters that likely overestimates the actual distribution encountered by the exposed population, yielding conservatively biased estimates of exposure. Over a 75-year lifetime, the estimated lifetime average daily dose of MC-LR from the consumption of drinking water was estimated to be 1.7 x 10 super(-3) mu g/kg-day with a standard deviation of 0.02. The 90 and 95 percentile exposure estimates were 1.5 x 10 super(-3) and 3.9 x 10 super(-3), respectively. Our results suggest that most individuals are exposed to cyanotoxin levels in finished North American drinking waters that are approximately an order of magnitude lower than the World Health Organization's provisional guideline level of 1 mu g/L, which corresponds to approximately 0.04 mu g/kg-day. JF - Lake and Reservoir Management AU - Fristachi, A AU - Rice, G AU - Steevens, J AU - Linkov, I AD - Oak Ridge Institute for Science and Education; assigned to U.S. Environmental Protection Agency, National Center for Environmental Assessment, 26 W. Martin Luther King Dr. (MS-A110), Cincinnati, Ohio 45268, USA, afristac@jhsph.edu Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 203 EP - 210 VL - 23 IS - 2 SN - 1040-2381, 1040-2381 KW - Ecology Abstracts; Pollution Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Water reservoirs KW - Biological poisons KW - Microcystins KW - microcystins KW - Water quality KW - Reservoir Management KW - USA KW - Lakes KW - Drinking Water KW - Public Health KW - Standard deviation KW - Assessments KW - Standard Deviation KW - Water treatment KW - guidelines KW - Exposure KW - Standards KW - Sampling KW - Microcystin-LR KW - Drinking water KW - Reservoirs KW - K 03330:Biochemistry KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - Q5 08521:Mechanical and natural changes KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19983090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lake+and+Reservoir+Management&rft.atitle=A+preliminary+exposure+assessment+of+microcystins+from+consumption+of+drinking+water+in+the+United+States&rft.au=Fristachi%2C+A%3BRice%2C+G%3BSteevens%2C+J%3BLinkov%2C+I&rft.aulast=Fristachi&rft.aufirst=A&rft.date=2007-06-01&rft.volume=23&rft.issue=2&rft.spage=203&rft.isbn=&rft.btitle=&rft.title=Lake+and+Reservoir+Management&rft.issn=10402381&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Water reservoirs; Water treatment; Biological poisons; Water quality; Standard deviation; Microcystins; Microcystin-LR; Sampling; Drinking water; Lakes; guidelines; microcystins; Reservoirs; Reservoir Management; Public Health; Drinking Water; Standard Deviation; Assessments; Exposure; Standards; USA ER - TY - JOUR T1 - Support for selection of a methamphetamine cleanup standard in Colorado AN - 19802986; 8253468 AB - Methamphetamine production for illicit use occurs in makeshift labs and is associated with the release of numerous chemicals, including methamphetamine residues. These methamphetamine residues may pose a health risk to residents who reoccupy these structures after property seizures. Several states have established technology-based cleanup standards for methamphetamine, but none have examined the health-protectiveness of these standards. In response to Colorado House Bill 04-1182, exposure intakes correlated with three technology-based standards were calculated for various groups of individuals. Intakes were assessed for a 1-year-old infant, 6-year-old child, and a female of childbearing age. Exposure intakes were compared to toxicity reference values developed from developmental endpoints following methamphetamine exposure from the available literature. Uncertainty factors were applied to the lowest adverse effect levels observed in these studies to arrive at the toxicity reference values. These reference values were greater than the calculated intakes from each proposed technology standard, suggesting that all of the proposed standards would be protective of human health exposure. The cost and practicality of attaining each of the proposed standards was also factored into the decision making process. In their final regulation (6 CCR 1014-3), the CDPHE selected 0.5 mu g/100cm super(2) as the final cleanup standard for methamphetamine residues. JF - Regulatory Toxicology and Pharmacology AU - Hammon, T L AU - Griffin, S AD - 999 18th Street, Suite 500, Denver, CO 80202, USA, griffin.susan@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 102 EP - 114 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 48 IS - 1 SN - 0273-2300, 0273-2300 KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Chemicals KW - Houses KW - Age KW - Residues KW - Housing KW - Seizures KW - Toxicity KW - Decision making KW - USA, Colorado KW - Methamphetamine KW - Residential areas KW - methamphetamine KW - Side effects KW - Technology KW - Infants KW - X 24380:Social Poisons & Drug Abuse KW - H 14000:Toxicology KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19802986?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+Toxicology+and+Pharmacology&rft.atitle=Support+for+selection+of+a+methamphetamine+cleanup+standard+in+Colorado&rft.au=Hammon%2C+T+L%3BGriffin%2C+S&rft.aulast=Hammon&rft.aufirst=T&rft.date=2007-06-01&rft.volume=48&rft.issue=1&rft.spage=102&rft.isbn=&rft.btitle=&rft.title=Regulatory+Toxicology+and+Pharmacology&rft.issn=02732300&rft_id=info:doi/10.1016%2Fj.yrtph.2007.02.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Decision making; Age; Houses; Methamphetamine; Seizures; Toxicity; Side effects; Infants; Chemicals; Housing; Residues; Residential areas; methamphetamine; Technology; USA, Colorado DO - http://dx.doi.org/10.1016/j.yrtph.2007.02.002 ER - TY - JOUR T1 - Distribution of super(1) super(4)C-atrazine following an acute lactational exposure in the Wistar rat AN - 19723324; 7499154 AB - The purpose of the present study was to examine the distribution of atrazine in the lactating dam and suckling neonate following an acute exposure to either 2 or 4mg/kg super(1) super(4)C-atrazine ( super(1) super(4)C-ATR) by gavage. super(1) super(4)C-ATR was administered to the nursing dam on postnatal day 3 by oral gavage. Two and a half hours after exposure of the mother to super(1) super(4)C-ATR, the pups were allowed to nurse for 30min. At the end of the nursing period, radiolabelled residues of super(1) super(4)C-ATR [or super(1) super(4)C-chlorotriazines ( super(1) super(4)C-ClTRI)] were measured in the organs and tissues of the perfused dam and in the stomachs and brains of the rat pups. Both the 2 and the 4mg atrazine treatments resulted in a transfer of approximately 0.007% of super(1) super(4)C-ClTRI to the stomach (indicator of milk content) and 0.0002% to the brains of the offspring following the 30-min nursing period. Three hours following the dose of super(1) super(4)C-ATR, there was a distribution of super(1) super(4)C-ClTRI to the organs of the dam, with the highest amounts in the liver and kidney (1.1 and 0.3% of the administered dose, respectively). Approximately 0.003% of the administered dose was present in three different brain sections of the dam following both doses of super(1) super(4)C-ATR. The results of this study demonstrate that super(1) super(4)C-ClTRI are present in small concentrations in the brain and tissues of the dam (adult female) and provide evidence that atrazine or the metabolites can have direct effects on neuroendrocrine function. The results also provide information for postnatal distribution into the suckling neonate during early lactation. JF - Reproductive Toxicology AU - Stoker, TE AU - Cooper, R L AD - Reproductive Toxicology Division, MD-72, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, United States, stoker.tammy@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 607 EP - 610 PB - Elsevier Science Inc., Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 23 IS - 4 SN - 0890-6238, 0890-6238 KW - Toxicology Abstracts KW - Milk KW - Brain KW - Suckling behavior KW - Metabolites KW - Lactation KW - Nursing KW - Atrazine KW - Kidney KW - Liver KW - Progeny KW - Neonates KW - Stomach KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19723324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reproductive+Toxicology&rft.atitle=Distribution+of+super%281%29+super%284%29C-atrazine+following+an+acute+lactational+exposure+in+the+Wistar+rat&rft.au=Stoker%2C+TE%3BCooper%2C+R+L&rft.aulast=Stoker&rft.aufirst=TE&rft.date=2007-06-01&rft.volume=23&rft.issue=4&rft.spage=607&rft.isbn=&rft.btitle=&rft.title=Reproductive+Toxicology&rft.issn=08906238&rft_id=info:doi/10.1016%2Fj.reprotox.2007.02.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Milk; Nursing; Atrazine; Liver; Kidney; Brain; Suckling behavior; Metabolites; Progeny; Neonates; Stomach; Lactation DO - http://dx.doi.org/10.1016/j.reprotox.2007.02.004 ER - TY - JOUR T1 - Moderating influence of the drinking water disinfection by-product dibromoacetic acid on a dithiocarbamate-induced suppression of the luteinizing hormone surge in female rats AN - 19721843; 7499146 AB - The disinfection by-product dibromoacetic acid (DBA) has been found in female rats to increase circulating concentrations of both estradiol (E2) and estrone (E1). This effect is apparently due, at least in part, to a suppression in hepatic catabolism. The present study investigated whether DBA, by increasing sex steroid levels, is able either to augment the hypothalamic up-regulation involved in triggering a luteinizing hormone (LH) surge, or to affect the ability of the neurotoxicant sodium dimethyldithiocarbamate (DMDC) to block the surge. Sprague-Dawley rats were gavaged for 14 days with DBA (0-150mg/kg) and ovariectomized on dosing day 11, and at the same time implanted with an estradiol capsule to generate daily LH surges. An injection of 0.1mM/kg DMDC was administered at 13:00h on day 14 and blood was sampled over the afternoon. DBA induced a dose-related increase in total estrogens. For identified surges, areas under the LH curve partitioned into two groups, comprising the two lower (0 and 37.5mg/kg DBA) and the two higher (75 and 150mg/kg) treatment groups. Consequently, low and high DBA groups were compared and found to be significantly different. At 150mg DBA /0.1mM DMDC, the timing of an identifiable LH peak was comparable to non-DMDC females, unlike the 37.5mg DBA/0.1mM DMDC group in which the appearance of peak concentrations was delayed. A significant effect with DBA treatment alone was not present. Results indicated that this exposure to DBA induced a dose-related increase in total estrogen concentrations that paralleled a diminished DMDC blockade of the LH surge. The effect appeared to be attributable to an augmentation in the estrogen-associated up-regulation in brain mechanisms stimulating the surge. JF - Reproductive Toxicology AU - Goldman, J M AU - Murr, A S AU - Buckalew, A R AU - Ferrell, J M AU - Cooper, R L AD - Reproductive Toxicology Division, National Health & Environmental Effects Research Laboratory, Office of Research & Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, United States, goldman.jerome@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 541 EP - 549 PB - Elsevier Science Inc., Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 23 IS - 4 SN - 0890-6238, 0890-6238 KW - Toxicology Abstracts KW - Disinfection KW - Hypothalamus KW - Estrogens KW - Brain KW - Steroid hormones KW - Estradiol KW - Sodium KW - Blood KW - Luteinizing hormone KW - Liver KW - Ovariectomy KW - Drinking water KW - Menopause KW - Estrone KW - X 24320:Food Additives & Contaminants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19721843?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reproductive+Toxicology&rft.atitle=Moderating+influence+of+the+drinking+water+disinfection+by-product+dibromoacetic+acid+on+a+dithiocarbamate-induced+suppression+of+the+luteinizing+hormone+surge+in+female+rats&rft.au=Goldman%2C+J+M%3BMurr%2C+A+S%3BBuckalew%2C+A+R%3BFerrell%2C+J+M%3BCooper%2C+R+L&rft.aulast=Goldman&rft.aufirst=J&rft.date=2007-06-01&rft.volume=23&rft.issue=4&rft.spage=541&rft.isbn=&rft.btitle=&rft.title=Reproductive+Toxicology&rft.issn=08906238&rft_id=info:doi/10.1016%2Fj.reprotox.2007.03.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Disinfection; Estrogens; Hypothalamus; Brain; Steroid hormones; Estradiol; Sodium; Blood; Luteinizing hormone; Liver; Ovariectomy; Drinking water; Menopause; Estrone DO - http://dx.doi.org/10.1016/j.reprotox.2007.03.001 ER - TY - JOUR T1 - Sensitivity of Fetal Rat Testicular Steroidogenesis to Maternal Prochloraz Exposure and the Underlying Mechanism of Inhibition AN - 19683774; 7421963 AB - The fungicide prochloraz (PCZ) induces malformations in androgen-dependent tissues in male rats when administered during sex differentiation. The sensitivity of fetal testicular steroidogenesis to PCZ was investigated to test the hypothesis that the reported morphological effects from maternal exposure were associated with reduced testosterone synthesis. Pregnant Sprague-Dawley rats were dosed by gavage with 0, 7.8, 15.6, 31.3, 62.5, and 125 mg PCZ/kg/day (n = 8) from gestational day (GD) 14 to 18. On GD 18, the effects of PCZ on fetal steroidogenesis were assessed by measuring hormone production from ex vivo fetal testes after a 3-h incubation. Lastly, PCZ levels in amniotic fluid and maternal serum were measured using liquid chromatography/mass spectroscopy and correlated to the inhibition of steroidogenesis. Fetal progesterone and 17 alpha -hydroxyprogesterone production levels were increased significantly at every PCZ dose, whereas testosterone levels were significantly decreased only at the two high doses. These results suggest that PCZ inhibits the conversion of progesterone to testosterone through the inhibition of CYP17. To test this hypothesis, PCZ effects on CYP17 gene expression and in vitro CYP17 hydroxylase activity were evaluated. PCZ had no effect on testicular CYP17 mRNA levels as measured by quantitative real-time polymersase chain reaction. However, microsomal CYP17 hydroxylase activity was significantly inhibited by the fungicide (K sub(i) = 865nM). Amniotic fluid PCZ concentrations ranged from 78 to 1512 ppb (207-4014nM) and testosterone production was reduced when PCZ reached similar to 500 ppb, which compares favorably with the determined CYP17 hydroxylase K sub(i) (326 ppb). These results demonstrate that PCZ lowers testicular testosterone synthesis by inhibiting CYP17 activity which likely contributes to the induced malformations in androgen-dependent tissues of male offspring. JF - Toxicological Sciences AU - Blystone, Chad R AU - Lambright, Christy S AU - Howdeshell, Kembra L AU - Furr, Johnathan AU - Sternberg, Robin M AU - Butterworth, Brian C AU - Durhan, Elizabeth J AU - Makynen, Elizabeth A AU - Ankley, Gerald T AU - Wilson, Vickie S AU - LeBlanc, Gerald A AU - Gray, LEarl Jr AD - Department of Environmental and Molecular Toxicology, NC State University, Raleigh, North Carolina 27695. U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Reproductive Toxicology Division, Research Triangle Park, North Carolina 27711. U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, Duluth, Minnesota, 55804 Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 512 EP - 519 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 97 IS - 2 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Amniotic fluid KW - Testes KW - Progesterone KW - Sex differentiation KW - Hormones KW - Steroidogenesis KW - Fetuses KW - Pregnancy KW - Testosterone KW - Prochloraz KW - Steroid 17 alpha -monooxygenase KW - Liquid chromatography KW - Fungicides KW - Progeny KW - Hydroxylase KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19683774?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Sensitivity+of+Fetal+Rat+Testicular+Steroidogenesis+to+Maternal+Prochloraz+Exposure+and+the+Underlying+Mechanism+of+Inhibition&rft.au=Blystone%2C+Chad+R%3BLambright%2C+Christy+S%3BHowdeshell%2C+Kembra+L%3BFurr%2C+Johnathan%3BSternberg%2C+Robin+M%3BButterworth%2C+Brian+C%3BDurhan%2C+Elizabeth+J%3BMakynen%2C+Elizabeth+A%3BAnkley%2C+Gerald+T%3BWilson%2C+Vickie+S%3BLeBlanc%2C+Gerald+A%3BGray%2C+LEarl+Jr&rft.aulast=Blystone&rft.aufirst=Chad&rft.date=2007-06-01&rft.volume=97&rft.issue=2&rft.spage=512&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Testes; Amniotic fluid; Progesterone; Sex differentiation; Steroidogenesis; Hormones; Fetuses; Pregnancy; Testosterone; Steroid 17 alpha -monooxygenase; Prochloraz; Liquid chromatography; Fungicides; Progeny; Hydroxylase ER - TY - JOUR T1 - In Vitro-In Vivo Extrapolation of Quantitative Hepatic Biotransformation Data for Fish. II. Modeled Effects On Chemical Bioaccumulation AN - 19677003; 7432282 AB - Hypothetical in vitro biotransformation rate and affinity values for fish were extrapolated to a set of in vivo whole-body metabolism rate constants. A one-compartment model was then used to investigate potential effects of metabolism on chemical bioaccumulation as a function of octanol/water partitioning (K sub(OW)). In a second model-based effort, in vitro data were incorporated into a physiologically based toxicokinetic (PBTK) model for fish. The two models predict similar effects on bioaccumulation when calculated in vivo intrinsic clearance values (CL sub(IN[hairsp]" VIVO,INT)) are less than 50% of estimated liver blood flow (Q sub(LIVER)). When CL sub(IN[hairsp]" VIVO,INT) approaches Q sub(LIVER), the PBTK model predicts a greater effect on bioaccumulation than the one-compartment model. This result is attributed to the structure of the PBTK model, which provides for first-pass clearance of chemicals taken up from food. Uncertainties inherent to in vitro-in vivo extrapolations of hepatic metabolism data include the effects of protein binding, inaccurate estimation of in vivo metabolism by in vitro assays, and failure to account for metabolism in other tissues. Model- based predictions of bioaccumulation within a natural setting also must account for possible metabolism at multiple trophic levels. The models described in this study can be used to perform in vitro-in vivo metabolism comparisons with fish, estimate in vitro biotransformation parameters on the basis of measured chemical residues in field-collected animals, and calculate the level of in vitro metabolic activity required to limit bioaccumulation of all compounds to a specified value. JF - Environmental Toxicology and Chemistry AU - Nichols, John W AU - Fitzsimmons, Patrick N AU - Burkhard, Lawrence P AD - U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804 Y1 - 2007/06// PY - 2007 DA - June 2007 SP - 1304 EP - 1319 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 26 IS - 6 SN - 0730-7268, 0730-7268 KW - Pollution Abstracts; Toxicology Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Biotransformation KW - Bioaccumulation KW - In vitro-in vivo extrapolation KW - Prediction KW - Blood circulation KW - Food KW - Physiology KW - biotransformation KW - Pollution effects KW - Toxicity tests KW - Models KW - Pisces KW - octanol KW - Assay KW - Toxicology KW - Residues KW - Toxicity KW - affinity KW - Trophic levels KW - Model Studies KW - Blood KW - Foods KW - Fish physiology KW - Liver KW - Proteins KW - Protein turnover KW - Fish KW - Metabolism KW - Q5 08504:Effects on organisms KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19677003?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=In+Vitro-In+Vivo+Extrapolation+of+Quantitative+Hepatic+Biotransformation+Data+for+Fish.+II.+Modeled+Effects+On+Chemical+Bioaccumulation&rft.au=Nichols%2C+John+W%3BFitzsimmons%2C+Patrick+N%3BBurkhard%2C+Lawrence+P&rft.aulast=Nichols&rft.aufirst=John&rft.date=2007-06-01&rft.volume=26&rft.issue=6&rft.spage=1304&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F06-259R.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Bioaccumulation; Blood circulation; Fish physiology; Pollution effects; Toxicity tests; Toxicology; Trophic levels; Food; octanol; Liver; biotransformation; Protein turnover; Metabolism; Models; Residues; Physiology; Proteins; Toxicity; affinity; Prediction; Blood; Foods; Biotransformation; Assay; Fish; Model Studies; Pisces DO - http://dx.doi.org/10.1897/06-259R.1 ER - TY - JOUR T1 - Low-Dose Effects of Ammonium Perchlorate on the Hypothalamic-Pituitary-Thyroid Axis of Adult Male Rats Pretreated with PCB126 AN - 19669239; 7421945 AB - The objective of this research was to characterize the disturbances in the hypothalamic-pituitary-thyroid (HPT) axis resulting from exposure to a binary mixture, 3,3',4,4',5-pentachlorobiphenyl (PCB126) and perchlorate (ClO[Formula: see text]), known to cause hypothyroidism by different modes of action. Two studies were conducted to determine the HPT axis effects of ClO[Formula: see text] on adult male Sprague-Dawley rats pretreated with PCB126. In dosing study I, rats were administered a single oral dose of PCB126 (0, 7.5, or 75 mu g/kg) on day 0 and 9 days later ClO[Formula: see text] (0, 0.01, 0.1, or 1 mg/kg day) was added to the drinking water until euthanasia on day 22. Significant dose-dependent trends were found for all thyroid function indices measured following ClO[Formula: see text] in drinking water for 14 days. Seventy-five micrograms PCB126/kg resulted in a significant increase in hepatic T sub(4)-glucuronide formation, causing a decline in serum thyroxine and fT sub(4), and resulting in increased serum thyroid-stimulating hormone (TSH). Serum TSH was also increased in animals that received 7.5 mu g PCB126/kg; no other HPT axis alterations were found in these animals. When pretreated with PCB126, the ClO[Formula: see text] dose trends disappeared, suggesting a less than additive effect on the HPT axis. In dosing study II, animals were given lower doses of PCB126 (0, 0.075, 0.75, or 7.5 mu g/kg) on day 0, and followed with ClO[Formula: see text] (0 or 0.01 mg/kg day) in drinking water beginning on day 1 and continuing for several days to explore transient HPT axis effects. No statistical effects were seen for PCB126 or ClO[Formula: see text] alone, and no perturbations were found when administered sequentially in dosing study II. In conclusion, these studies demonstrate that HPT axis disturbances following exposure to ClO[Formula: see text] are less than additive when pretreated with relatively high doses of PCB126. At relatively low doses, at or near the no-observed-effect-level for PCB126 and ClO[Formula: see text], no interactions between the chemicals occur. JF - Toxicological Sciences AU - McLanahan, Eva D AU - Campbell, Jerry LJr AU - Ferguson, Duncan C AU - Harmon, Barry AU - Hedge, Joan M AU - Crofton, Kevin M AU - Mattie, David R AU - Braverman, Lewis AU - Keys, Deborah A AU - Mumtaz, Moiz AU - Fisher, Jeffrey W AD - Interdisciplinary Toxicology Program, University of Georgia, Athens, Georgia 30602. Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602. Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711. Air Force Research Laboratory, Human Effectiveness Directorate, Biosciences and Protection Division, Applied Biotechnology Branch, Wright-Patterson Air Force Base, Ohio 45433. Section of Endocrinology, Diabetes, and Nutrition Center, Boston Medical Center, Boston, Massachusetts 02118. Statistics and Modeling Supporting Informed Decisions, Athens, Georgia 30606. Division of Toxicology, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30333 Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 308 EP - 317 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 97 IS - 2 SN - 1096-6080, 1096-6080 KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - Ammonium KW - Hypothalamus KW - Statistics KW - 3,3',4,4',5-Pentachlorobiphenyl KW - Thyroxine KW - Thyroid KW - Liver KW - Hypothyroidism KW - Thyroid-stimulating hormone KW - Perchloric acid KW - Drinking water KW - N3 11028:Neuropharmacology & toxicology KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19669239?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Low-Dose+Effects+of+Ammonium+Perchlorate+on+the+Hypothalamic-Pituitary-Thyroid+Axis+of+Adult+Male+Rats+Pretreated+with+PCB126&rft.au=McLanahan%2C+Eva+D%3BCampbell%2C+Jerry+LJr%3BFerguson%2C+Duncan+C%3BHarmon%2C+Barry%3BHedge%2C+Joan+M%3BCrofton%2C+Kevin+M%3BMattie%2C+David+R%3BBraverman%2C+Lewis%3BKeys%2C+Deborah+A%3BMumtaz%2C+Moiz%3BFisher%2C+Jeffrey+W&rft.aulast=McLanahan&rft.aufirst=Eva&rft.date=2007-06-01&rft.volume=97&rft.issue=2&rft.spage=308&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Ammonium; Hypothalamus; Statistics; Liver; Thyroid; Thyroxine; 3,3',4,4',5-Pentachlorobiphenyl; Hypothyroidism; Perchloric acid; Thyroid-stimulating hormone; Drinking water ER - TY - JOUR T1 - U.S. environmental protection agency's activities to prepare for regulatory and risk assessment applications of genomics information AN - 19463120; 7763390 AB - Genomics is expected to have significant implications for risk assessment and regulatory decision making. Since 2002, the U.S. Environmental Protection Agency (EPA) has undertaken a number of cross-agency activities to further prepare itself to receive, interpret, and apply genomics information for risk assessment and regulatory purposes. These activities include: (1) the issuance of an Interim Genomics Policy on the use of genomics information in risk assessments and decision making, (2) the release of the 2004 Genomics White Paper, which outlines potential applications and implications of genomics for EPA, and (3) the recent release of the external review draft of the Interim Guidance on Microarray-Based Assays, which outlines data submission, quality, analysis, management, and training considerations for such data. This manuscript discusses these activities and more recent follow-up activities with the aim of further communicating these efforts to the broader scientific and stakeholder community. JF - Environmental and Molecular Mutagenesis AU - Benson, William H AU - Gallagher, Kathryn AU - McClintock, J Thomas AD - Office of the Science Advisor, U.S. Environmental Protection Agency, Washington, D.C., gallagher.kathryn@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 359 EP - 362 PB - John Wiley & Sons, 111 River Street Hoboken NJ 07030 USA, [mailto:custserv@wiley.com], [URL:http://www.wiley.com/] VL - 48 IS - 5 SN - 0893-6692, 0893-6692 KW - Pollution Abstracts; Genetics Abstracts; Toxicology Abstracts KW - Risk assessment KW - Data processing KW - Training KW - Mutagenesis KW - EPA KW - Decision making KW - USA KW - Reviews KW - genomics KW - stakeholders KW - P 9000:ENVIRONMENTAL ACTION KW - G 07880:Human Genetics KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19463120?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+and+Molecular+Mutagenesis&rft.atitle=U.S.+environmental+protection+agency%27s+activities+to+prepare+for+regulatory+and+risk+assessment+applications+of+genomics+information&rft.au=Benson%2C+William+H%3BGallagher%2C+Kathryn%3BMcClintock%2C+J+Thomas&rft.aulast=Benson&rft.aufirst=William&rft.date=2007-06-01&rft.volume=48&rft.issue=5&rft.spage=359&rft.isbn=&rft.btitle=&rft.title=Environmental+and+Molecular+Mutagenesis&rft.issn=08936692&rft_id=info:doi/10.1002%2Fem.20302 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Decision making; Data processing; Reviews; genomics; Mutagenesis; EPA; Training; stakeholders; USA DO - http://dx.doi.org/10.1002/em.20302 ER - TY - JOUR T1 - The Implications of Global Priorities for Biodiversity and Ecosystem Services Associated with Protected Areas, USA AN - 19400755; 8497239 AB - Map-based prioritization systems have become ubiquitous tools for allocating resources for biological conservation. Although the scientific basis for these systems continues to be debated, they have become a significant factor in international conservation. A recent study found that published conservation priorities are associated with over one third of conservation spending by major international nongovernmental organizations totaling over $1.5 x 10 super(9) in 2002 alone. The growing influence of these systems on the allocation of resources for conservation underscores the need to understand their ecological and environmental implications. This paper addresses the role of global priorities in contributing to the future of land protection by considering three key questions: (1) What are the implications of business-as-usual growth in land protection for the representation of biodiversity, i.e., the absence of priorities? (2) Would implementing global conservation prioritization systems change trends in biodiversity representation, i.e., conservation following priorities? (3) What are the implications of priority system-guided protected area growth for ecosystem services beyond biodiversity representation, i.e., nontarget consequences of implementation? These questions are addressed with analyses of information from the World Database for Protected Areas and the Global Gap Analysis. The results indicate that business-as-usual growth in land protection will fill gaps slowly, most likely at a rate equivalent to chance. Following global priority systems would accelerate conservation of unprotected biodiversity, gap species; however, achieving these gains would exacerbate the current highly uneven global distribution of protected areas. The majority of areas targeted by priority systems already have above average levels of protection and additions following global priority systems would encourage growth in these already above average countries. Over time, these patterns could contribute to uneven distributions of important ecosystem services. This observation does not detract from the value of global priority systems for biodiversity conservation, but it does highlight their limitations and suggest the need for more comprehensive approaches to planning and prioritizing future land protection. JF - Ecology and Society AU - Pyke, C R AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency Y1 - 2007/06// PY - 2007 DA - Jun 2007 VL - 12 IS - 1 SN - 1708-3087, 1708-3087 KW - Ecology Abstracts; Sustainability Science Abstracts KW - resource allocation KW - nongovernmental organizations KW - Biodiversity KW - Biological diversity KW - Databases KW - protected areas KW - USA KW - Conservation KW - Gap analysis KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19400755?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecology+and+Society&rft.atitle=The+Implications+of+Global+Priorities+for+Biodiversity+and+Ecosystem+Services+Associated+with+Protected+Areas%2C+USA&rft.au=Pyke%2C+C+R&rft.aulast=Pyke&rft.aufirst=C&rft.date=2007-06-01&rft.volume=21&rft.issue=8&rft.spage=1172&rft.isbn=&rft.btitle=&rft.title=Environmental+Modelling+%26+Software&rft.issn=13648152&rft_id=info:doi/10.1016%2Fj.envsoft.2005.06.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA; Conservation; Biological diversity; protected areas; nongovernmental organizations; resource allocation; Biodiversity; Gap analysis; Databases ER - TY - JOUR T1 - A critical evaluation of a flow cytometer used for detecting enterococci in recreational waters AN - 19295474; 7475252 AB - The current U. S. Environmental Protection Agency-approved method for enterococci (Method 1600) in recreational water is a membrane filter (MF) method that takes 24 hours to obtain results. If the recreational water is not in compliance with the standard, the risk of exposure to enteric pathogens may occur before the water is identified as hazardous. Because flow cytometry combined with specific fluorescent antibodies has the potential to be used as a rapid detection method for microorganisms, this technology was evaluated as a rapid, same-day method to detect enterococci in bathing beach waters. The flow cytometer chosen for this study was a laser microbial detection system designed to detect labeled antibodies. A comparison of MF counts with flow cytometry counts of enterococci in phosphate buffer and sterile-filtered recreational water showed good agreement between the two methods. However, when flow cytometry was used, the counts were several orders of magnitude higher than the MF counts with no correlation to Enterococcus spike concentrations. The unspiked sample controls frequently had higher counts than the samples spiked with enterococci. Particles within the spiked water samples were probably counted as target cells by the flow cytometer because of autofluorescence or non-specific adsorption of antibody and carryover to subsequent samples. For these reasons, this technology may not be suitable for enterococci detection in recreational waters. Improvements in research and instrument design that will eliminate high background and carryover may make this a viable technology in the future. JF - Journal of Water and Health AU - King, D N AU - Brenner, K P AU - Rodgers, M R AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, 26 W. Martin Luther King Dr., Cincinnati OH 45268, USA, king.dawn@epa.gov PY - 2007 SP - 295 EP - 306 VL - 5 IS - 2 SN - 1477-8920, 1477-8920 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Pollution Abstracts; Health & Safety Science Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Water sampling KW - Water Analysis KW - Compliance KW - Particulates KW - Water quality KW - Evaluation KW - Flow cytometry KW - Beaches KW - Environmental Protection KW - Pathogens KW - Environmental protection KW - Filters KW - Antibodies KW - Phosphates KW - Phosphate KW - Recreation areas KW - Enterococcus KW - Microorganisms KW - Adsorption KW - Standards KW - Lasers KW - Technology KW - H 3000:Environment and Ecology KW - A 01450:Environmental Pollution & Waste Treatment KW - P 2000:FRESHWATER POLLUTION KW - SW 3030:Effects of pollution KW - AQ 00008:Effects of Pollution KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19295474?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+and+Health&rft.atitle=A+critical+evaluation+of+a+flow+cytometer+used+for+detecting+enterococci+in+recreational+waters&rft.au=King%2C+D+N%3BBrenner%2C+K+P%3BRodgers%2C+M+R&rft.aulast=King&rft.aufirst=D&rft.date=2007-06-01&rft.volume=5&rft.issue=2&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+and+Health&rft.issn=14778920&rft_id=info:doi/10.2166%2Fwh.2007.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-12-16 N1 - SubjectsTermNotLitGenreText - Filters; Flow cytometry; Beaches; Antibodies; Phosphate; Adsorption; Microorganisms; Lasers; Pathogens; Environmental protection; Phosphates; Water sampling; Recreation areas; Compliance; Particulates; Water quality; Technology; Evaluation; Water Analysis; Environmental Protection; Standards; Enterococcus DO - http://dx.doi.org/10.2166/wh.2007.012 ER - TY - JOUR T1 - Reach-scale geomorphology affects organic matter and consumer delta super(13)C in a forested Piedmont stream AN - 1560133540; 20611108 AB - 1. We investigated the spatial (longitudinal position and reach geomorphology) and seasonal (spring and autumn) influences on the variation of delta super(13)C among organic matter sources and consumers in a forested Piedmont river, South Carolina, U.S.A. 2. Six sites were sampled along a continuum and varied in basin area from approximately 30 to 300km super(2). Sites fell into two geomorphic categories (i) high-gradient, rock bed ('rock') or (ii) low-gradient, sand bed ('sand') sites. 3. Variation in delta super(13)C was more strongly related to reach geomorphology than longitudinal position. delta super(13)C of biofilm and consumers was consistently enriched at rock sites. Leaf litter (i.e. coarse particulate organic matter, CPOM) delta super(13)C did not vary with bed type. There was significant delta super(13)C enrichment at rock sites for biofilm, seston, fine benthic organic matter (FBOM), and eight of nine consumer trophic guilds (e.g. grazing invertebrates, insectivorous fishes). delta super(13)C of biofilm and four trophic guilds was also positively correlated with drainage area, but the magnitude of enrichment was less than between bed types. 4. delta super(13)C was generally enriched in spring, but this varied among organic matter types, consumers, and by bed type. CPOM and seston were enriched in spring, FBOM was enriched in autumn, and biofilm showed no trend. Five consumer guilds were enriched in spring, and only one fish guild, generalised carnivores, showed enrichment of muscle tissue in autumn. 5. Consumer delta super(13)C enrichment at rock sites suggests greater reliance on algal carbon than for consumers at sand sites, but we also found delta super(13)C enrichment of biofilm at rock sites. Thus, differences in consumer delta super(13)C between bed types could be related to (i) increased consumption of biofilm at rock compared with sand sites, or (ii) consumption of biofilm at rock sites that is enriched relative to biofilm at sand sites or (iii) both mechanisms. 6. delta super(13)C signatures in local food webs appear to respond to processes operating at multiple spatial scales. Overall downstream enrichment of biofilm and consumers was disrupted by strong local effects related to bed morphology. These results suggest that human alteration of channel habitat will have corresponding effects on stream food webs, as assessed by changes in delta super(13)C. JF - Freshwater Biology AU - Walters, D M AU - Fritz, K M AU - Phillips, D L AD - U.S. Environmental Protection Agency, National Exposure Research Laboratory, Cincinnati, OH, U.S.A. Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 1105 EP - 1119 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 52 IS - 6 SN - 0046-5070, 0046-5070 KW - Ecology Abstracts; Water Resources Abstracts; Aqualine Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Carbon isotopes KW - Basins KW - Freshwater KW - Food Chains KW - Geomorphology KW - Organic Matter KW - Consumers KW - USA, North Carolina, Piedmont KW - Enrichment KW - Algae KW - Rivers KW - Fluvial morphology KW - Grazing KW - Muscles KW - Habitat KW - Leaf litter KW - Seston KW - Guilds KW - Stream KW - Fish KW - Streams KW - USA, South Carolina KW - Carbon KW - Trophic structure KW - Sand KW - Biofilms KW - Food webs KW - Drainage KW - Organic matter KW - Carnivores KW - Particulate organic matter KW - Scales KW - AQ 00001:Water Resources and Supplies KW - SW 5010:Network design KW - Q1 08463:Habitat community studies KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560133540?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Freshwater+Biology&rft.atitle=Reach-scale+geomorphology+affects+organic+matter+and+consumer+delta+super%2813%29C+in+a+forested+Piedmont+stream&rft.au=Walters%2C+D+M%3BFritz%2C+K+M%3BPhillips%2C+D+L&rft.aulast=Walters&rft.aufirst=D&rft.date=2007-06-01&rft.volume=52&rft.issue=6&rft.spage=1105&rft.isbn=&rft.btitle=&rft.title=Freshwater+Biology&rft.issn=00465070&rft_id=info:doi/10.1111%2Fj.1365-2427.2007.01735.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Fluvial morphology; Trophic structure; Geomorphology; Stream; Organic matter; Carbon isotopes; Consumers; Biofilms; Food webs; Rivers; Grazing; Drainage; Carnivores; Muscles; Basins; Habitat; Streams; Leaf litter; Guilds; Seston; Carbon; Particulate organic matter; Sand; Scales; Algae; Food Chains; Organic Matter; Fish; Enrichment; USA, South Carolina; USA, North Carolina, Piedmont; Freshwater DO - http://dx.doi.org/10.1111/j.1365-2427.2007.01735.x ER - TY - JOUR T1 - Using biological assemblage composition to infer the values of covarying environmental factors AN - 1560127321; 20611116 AB - 1. Observations of different organisms can often be used to infer environmental conditions at a site. These inferences may be useful for diagnosing the causes of degradation in streams and rivers. 2. When used for diagnosis, biological inferences must not only provide accurate, unbiased predictions of environmental conditions, but also pairs of inferred environmental variables must covary no more strongly than actual measurements of those same environmental variables. 3. Mathematical analysis of the relationship between the measured and inferred values of different environmental variables provides an approach for comparing the covariance between measurements with the covariance between inferences. Then, simulated and field-collected data are used to assess the performance of weighted average and maximum likelihood inference methods. 4. Weighted average inferences became less accurate as covariance in the calibration data increased, whereas maximum likelihood inferences were unaffected by covariance in the calibration data. In contrast, the accuracy of weighted average inferences was unaffected by changes in measurement error, whilst the accuracy of maximum likelihood inferences decreased as measurement error increased. Weighted average inferences artificially increased the covariance of environmental variables beyond what was expected from measurements, whereas maximum likelihood inference methods more accurately reproduced the expected covariances. 5. Multivariate maximum likelihood inference methods can potentially provide more useful diagnostic information than single variable inference models. JF - Freshwater Biology AU - Yuan, Lester L AD - Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, U.S.A. Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 1159 EP - 1175 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 52 IS - 6 SN - 0046-5070, 0046-5070 KW - Environment Abstracts; Ecology Abstracts; Water Resources Abstracts; Aqualine Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Prediction KW - Degradation KW - Mathematical Analysis KW - Freshwater KW - Environmental factors KW - Streams KW - Models KW - Calibrations KW - Rivers KW - Data processing KW - Errors KW - Model Studies KW - Mathematical analysis KW - Performance Evaluation KW - Environmental conditions KW - SW 5010:Network design KW - Q1 08422:Environmental effects KW - D 04040:Ecosystem and Ecology Studies KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - ENA 19:Water Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560127321?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Freshwater+Biology&rft.atitle=Using+biological+assemblage+composition+to+infer+the+values+of+covarying+environmental+factors&rft.au=Yuan%2C+Lester+L&rft.aulast=Yuan&rft.aufirst=Lester&rft.date=2007-06-01&rft.volume=52&rft.issue=6&rft.spage=1159&rft.isbn=&rft.btitle=&rft.title=Freshwater+Biology&rft.issn=00465070&rft_id=info:doi/10.1111%2Fj.1365-2427.2007.01744.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Environmental conditions; Streams; Environmental factors; Mathematical analysis; Rivers; Data processing; Models; Prediction; Degradation; Performance Evaluation; Calibrations; Mathematical Analysis; Errors; Model Studies; Freshwater DO - http://dx.doi.org/10.1111/j.1365-2427.2007.01744.x ER - TY - JOUR T1 - THE ETHICS FORUM: REVEALING PERSONAL NEEDS TO PROSPECTIVE EMPLOYERS AN - 1323808626; 17839994 AB - A student member inquired about an important aspect of searching for employment. How much should an applicant reveal about personal needs when seeking a job? For example, should a job candidate reveal that a spouse might need a job, or that flexible working hours are necessary to pick up children from day care? On the one hand, a job candidate should be up front about his or her situation with a prospective employer. On the other hand, a candidate shouldn't do anything that might hinder his or her chance of getting the job. JF - Limnology and Oceanography Bulletin AU - Weissberger, E AD - U.S. Environmental Protection Agency, Atlantic Ecology Division, 21 Tarzwell Dr., Narragansett, RI 02882 USA, weissberger.eric@epa.gov Y1 - 2007/06// PY - 2007 DA - Jun 2007 SP - 41 EP - 42 VL - 16 IS - 2 SN - 1539-607X, 1539-607X KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Aqualine Abstracts; Water Resources Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323808626?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Limnology+and+Oceanography+Bulletin&rft.atitle=THE+ETHICS+FORUM%3A+REVEALING+PERSONAL+NEEDS+TO+PROSPECTIVE+EMPLOYERS&rft.au=Weissberger%2C+E&rft.aulast=Weissberger&rft.aufirst=E&rft.date=2007-06-01&rft.volume=16&rft.issue=2&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Limnology+and+Oceanography+Bulletin&rft.issn=1539607X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2013-04-05 ER - TY - JOUR T1 - Use of habitat-contamination spatial correlation to determine when to perform a spatially explicit ecological risk assessment AN - 19718019; 7497428 AB - Anthropogenic contamination is typically distributed heterogeneously through space. This spatial structure can have different effects on the cumulative doses of wildlife exposed to contamination within the environment. These effects are accentuated when individual organisms pursue different movement strategies, and movement strategies can be affected by how individual organisms and species value habitat. Habitat quality is often neglected when ecological risk assessments are performed, despite evidence that inclusion of a quantitative habitat measure can have a significant effect on the overall exposure estimate. We couple an exposure model with habitat data to examine the interactions between habitat preferences, the spatial distribution of contamination, and the resulting impact on dose estimates. Dose distributions are constructed for pronghorn (Antilocapra americana) exposed to fluoride when foraging on desert sagebrush. The results show the magnitude of the difference between simulated doses when foraging concentrations are positively or negatively correlated with different spatial distributions of habitat preferences. Mean estimated exposures obtained from non-spatial versus spatial methods can vary by a factor greater than two, and variation within the movement model, due to different habitat preferences, can vary by an order of magnitude. Such differences in calculated exposures can change a remediation decision from no-action to remediation, or vice-versa, and impact the remedial design when cleanup is required. In addition, information concerning which endpoint species are more or less likely to be exposed to chemical contamination in a given spatial setting can be used by stakeholders in the endpoint selection process. Results presented here are generally applicable to other situations where terrestrial wildlife is exposed to chemical contaminants. These simple model results demonstrate that examining the strength of the spatial correlation between habitat preference and contaminant data can be quickly used to determine when the implementation of a spatially explicit ecological risk assessment is useful. JF - Ecological Modelling AU - Purucker, ST AU - Welsh, CJE AU - Stewart, R N AU - Starzec, P AD - 960 College Station Road, Athens, GA 30605, USA, Purucker.Tom@epa.gov Y1 - 2007/05/24/ PY - 2007 DA - 2007 May 24 SP - 180 EP - 192 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 204 IS - 1-2 SN - 0304-3800, 0304-3800 KW - Ecology Abstracts KW - Risk assessment KW - Contamination KW - Spatial distribution KW - Wildlife KW - Habitat preferences KW - Habitat KW - Contaminants KW - Antilocapra americana KW - Models KW - D 04030:Models, Methods, Remote Sensing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19718019?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Use+of+habitat-contamination+spatial+correlation+to+determine+when+to+perform+a+spatially+explicit+ecological+risk+assessment&rft.au=Purucker%2C+ST%3BWelsh%2C+CJE%3BStewart%2C+R+N%3BStarzec%2C+P&rft.aulast=Purucker&rft.aufirst=ST&rft.date=2007-05-24&rft.volume=204&rft.issue=1-2&rft.spage=180&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2006.12.032 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Spatial distribution; Contamination; Wildlife; Habitat preferences; Contaminants; Habitat; Models; Antilocapra americana DO - http://dx.doi.org/10.1016/j.ecolmodel.2006.12.032 ER - TY - JOUR T1 - Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure. AN - 70501271; 17462840 AB - Exposure to phthalate esters during sexual differentiation disrupts testosterone and insulin-like three hormones resulting in malformations of androgen- and insulin-like three-dependent tissues. The current study was designed to test the hypothesis that gubernacular lesions would be more prevalent in the DEHP-treated (750 mg/kg/day, gestational days 14-18) Wistar male than in the SD rat offspring, whereas the SD rat would display a higher incidence of epididymal agenesis. As hypothesized, striking differences were seen in the incidences of epididymal (67% in SD versus 8% in Wistar) and gubernacular lesions (0% in SD versus 64% in Wistar) among the two strains. In addition, fetal androgen and insl3 mRNA levels differed among the strains. SD fetal males had higher insl3 mRNA and lower T levels than Wistar males. The ratio of insl3 mRNA to T differed among DEHP-treated SD and Wistar fetal males, indicating that the steroidogenic pathway was more affected in the SD strain than in the Wistar strain. Taken together, these results suggest that the different malformation profiles produced by in utero phthalate treatment arise, at least in part, from strain differences in fetal Leydig cell function and the manner in which these cells respond to DEHP treatment. JF - Toxicology letters AU - Wilson, Vickie S AU - Howdeshell, Kembra L AU - Lambright, Christy S AU - Furr, Johnathan AU - Earl Gray, L AD - U.S. Environmental Protection Agency, ORD, NHEERL, Reproductive Toxicology Division, MD-72, Research Triangle Park, NC 27711, USA. Y1 - 2007/05/15/ PY - 2007 DA - 2007 May 15 SP - 177 EP - 184 VL - 170 IS - 3 SN - 0378-4274, 0378-4274 KW - Testosterone KW - 3XMK78S47O KW - RNA KW - 63231-63-0 KW - Diethylhexyl Phthalate KW - C42K0PH13C KW - Index Medicus KW - Testis -- abnormalities KW - Animals KW - Testosterone -- metabolism KW - Intubation, Gastrointestinal KW - Testis -- pathology KW - Reverse Transcriptase Polymerase Chain Reaction KW - Fetus -- metabolism KW - Pregnancy KW - RNA -- biosynthesis KW - Rats KW - Genital Diseases, Male -- pathology KW - Rats, Sprague-Dawley KW - Rats, Wistar KW - Genital Diseases, Male -- epidemiology KW - Epididymis -- abnormalities KW - Genital Diseases, Male -- chemically induced KW - Species Specificity KW - Female KW - Male KW - RNA -- genetics KW - Prenatal Exposure Delayed Effects KW - Diethylhexyl Phthalate -- poisoning KW - Diethylhexyl Phthalate -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70501271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+letters&rft.atitle=Differential+expression+of+the+phthalate+syndrome+in+male+Sprague-Dawley+and+Wistar+rats+after+in+utero+DEHP+exposure.&rft.au=Wilson%2C+Vickie+S%3BHowdeshell%2C+Kembra+L%3BLambright%2C+Christy+S%3BFurr%2C+Johnathan%3BEarl+Gray%2C+L&rft.aulast=Wilson&rft.aufirst=Vickie&rft.date=2007-05-15&rft.volume=170&rft.issue=3&rft.spage=177&rft.isbn=&rft.btitle=&rft.title=Toxicology+letters&rft.issn=03784274&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-10 N1 - Date created - 2007-05-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Validation studies of thermal extraction-GC/MS applied to source emissions aerosols. 1. Semivolatile analyte-nonvolatile matrix interactions. AN - 70491738; 17425284 AB - In this work, we develop a novel validation approach for studying how nonvolatile aerosol matrixes of considerably different chemical composition potentially affect the thermal extraction (TE)-GC/MS quantification of a wide range of trace semivolatile organic markers. The nonvolatile matrixes of a set of source emissions aerosols are first operationally isolated by thermally clearing the aerosols of their native semivolatile organic matter. TE-GC/MS analysis is then performed in triplicate on matrixes refortified with multilevel organic compound standard suites. The spiking of empty thermal extraction tubes and blank quartz filters is introduced as experimental control and also allows for the calculation of method detection limits. For the vast majority of organic compounds fortifying the matrixes (e.g., the alkane, alkene, cycloalkane, sterane, and phthalate classes), the analytical bias observed was classified as either minor or nonexistent. Furthermore, compound recoveries were generally highly reproducible, demonstrating relative standard deviations of less than 20%. For a diesel engine exhaust sample, significant matrix effects for the six- and seven-ring polycyclic aromatic hydrocarbons (PAHs) are observed and ascribed to the high proportion of elemental carbon in the sample. Our results suggest that TE-GC/MS may underestimate inhalation exposures to PAHs (with 5 rings or more) in atmospheric aerosols replete with diesel engine exhaust (e.g., near roadways or in polluted urban air). Due to its stability and representativeness, the use of a thermally cleared particulate matter matrix for validation purposes is probably expandable to additional sample pretreatment and instrumental techniques also being applied to quantify organic molecular markers in source and atmospheric aerosols. JF - Analytical chemistry AU - Lavrich, Richard J AU - Hays, Michael D AD - United States Environmental Protection Agency, National Risk Management Research Laboratory, Research Triangle Park, North Carolina 27711, USA. Y1 - 2007/05/15/ PY - 2007 DA - 2007 May 15 SP - 3635 EP - 3645 VL - 79 IS - 10 SN - 0003-2700, 0003-2700 KW - Aerosols KW - 0 KW - Air Pollutants KW - Organic Chemicals KW - Polycyclic Aromatic Hydrocarbons KW - Vehicle Emissions KW - Index Medicus KW - Hot Temperature KW - Polycyclic Aromatic Hydrocarbons -- analysis KW - Volatilization KW - Organic Chemicals -- analysis KW - Air Pollutants -- analysis KW - Aerosols -- analysis KW - Gas Chromatography-Mass Spectrometry -- methods KW - Gas Chromatography-Mass Spectrometry -- standards KW - Vehicle Emissions -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70491738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Validation+studies+of+thermal+extraction-GC%2FMS+applied+to+source+emissions+aerosols.+1.+Semivolatile+analyte-nonvolatile+matrix+interactions.&rft.au=Lavrich%2C+Richard+J%3BHays%2C+Michael+D&rft.aulast=Lavrich&rft.aufirst=Richard&rft.date=2007-05-15&rft.volume=79&rft.issue=10&rft.spage=3635&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=00032700&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-06 N1 - Date created - 2007-05-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of acute and weekly episodic exposures to anatoxin-a on the motor activity of rats: comparison with nicotine. AN - 70370723; 17367909 AB - Anatoxin-a is a naturally occurring nicotinic agonist produced by cyanobacterial blooms; exposures are likely to occur episodically when the blooms repeatedly form and dissipate. Tolerance and sensitization to nicotine's effects on the motor activity of rats can occur when administered episodically at weekly intervals. It was therefore of interest to compare the effects of anatoxin-a and nicotine when given weekly. Adult male Long Evans rats were tested daily (M-F) in a photocell device, that recorded both horizontal and vertical motor activity, during 30-min sessions. Anatoxin-a and nicotine were given s.c. once a week for 4 weeks, just prior to a test session. Anatoxin-a was given as the (+) isomer and as the racemate. Dose ranges were: (+)anatoxin-a, 0.075-0.225 mg/kg; (+/-)anatoxin-a, 0.2-0.95 mg/kg; and (-)-nicotine, 0.3-1.8 mg/kg. Each experiment also included a saline-control group. Nicotine initially decreased both horizontal activity and, to a greater extent, vertical activity. Tolerance developed to nicotine's effects with weekly administration. Both forms of anatoxin-a also initially decreased horizontal and vertical activity, and to roughly equivalent degrees. Neither form of anatoxin-a, however, induced tolerance with weekly administration. Thus, anatoxin-a and nicotine can be distinguished by their effects on motor activity with episodic treatment, suggesting different sites of action for the compounds in the nervous system. JF - Toxicology AU - MacPhail, R C AU - Farmer, J D AU - Jarema, K A AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, US EPA, Research Triangle Park, NC 27711, USA. macphail.robert@epa.gov Y1 - 2007/05/05/ PY - 2007 DA - 2007 May 05 SP - 83 EP - 89 VL - 234 IS - 1-2 SN - 0300-483X, 0300-483X KW - Ganglionic Stimulants KW - 0 KW - Nicotinic Agonists KW - Tropanes KW - Nicotine KW - 6M3C89ZY6R KW - anatoxin a KW - 80023A73NK KW - Index Medicus KW - Rats KW - Nicotinic Agonists -- toxicity KW - Drug Tolerance KW - Animals KW - Stereoisomerism KW - Rats, Long-Evans KW - Dose-Response Relationship, Drug KW - Injections, Subcutaneous KW - Time Factors KW - Male KW - Ganglionic Stimulants -- toxicity KW - Nicotine -- toxicity KW - Tropanes -- chemistry KW - Tropanes -- toxicity KW - Motor Activity -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70370723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Effects+of+acute+and+weekly+episodic+exposures+to+anatoxin-a+on+the+motor+activity+of+rats%3A+comparison+with+nicotine.&rft.au=MacPhail%2C+R+C%3BFarmer%2C+J+D%3BJarema%2C+K+A&rft.aulast=MacPhail&rft.aufirst=R&rft.date=2007-05-05&rft.volume=234&rft.issue=1-2&rft.spage=83&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-13 N1 - Date created - 2007-04-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Spatial Analysis of Volatile Organic Compounds from a Community-Based Air Toxics Monitoring Network in Deer Park, Texas, USA AN - 759321945; 13772005 AB - In the summer of 2003, ambient air concentrations of volatile organic compounds (VOCs) were measured at 12 sites within a 3-km radius in Deer Park, Texas near Houston. The purpose of the study was to assess local spatial influence of traffic and other urban sources and was part of a larger investigation of VOC spatial and temporal heterogeneity influences in selected areas of Houston. Seventy 2-h samples were collected using passive organic vapor monitors. Most measurements of 13 VOC species were greater than the method detection limits. Samplers were located at 10 residential sites, a regulatory air monitoring station, and a site located at the centroid of the census tract in which the regulatory station was located. For residential sites, sampler placement locations (e. g., covered porch vs. house eaves) had no effect on concentration with the exception of methyl tertiary-butyl ether (MTBE). Relatively high correlations (Pearson r > 0.8) were found between toluene, ethylbenzene, and o,m,p-xylenes suggesting petroleum-related influence. Chloroform was not correlated with these species or benzene (Pearson r < 0.35) suggesting a different source influence, possibly from process-related activities. As shown in other spatial studies, wind direction relative to source location had an effect on VOC concentrations. JF - Environmental Monitoring and Assessment AU - Smith, Luther A AU - Stock, Thomas H AU - Chung, Kuenja C AU - Mukerjee, Shaibal AU - Liao, Xiaojuan L AU - Stallings, Casson AU - Afshar, Masoud AD - U.S. Environmental Protection Agency, National Exposure Research Laboratory, MD E205-02, Research Triangle Park, Durham, NC, 27711, USA, mukerjee.shaibal@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 369 EP - 379 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 128 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Environment Abstracts; Pollution Abstracts; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts KW - census KW - Environmental monitoring KW - Housing KW - Toluene KW - MTBE KW - Correlations KW - Organic compounds in atmosphere KW - Wind direction KW - community involvement KW - traffic KW - USA, Texas KW - USA, Texas, Houston KW - Volatile organic compounds KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759321945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=Spatial+Analysis+of+Volatile+Organic+Compounds+from+a+Community-Based+Air+Toxics+Monitoring+Network+in+Deer+Park%2C+Texas%2C+USA&rft.au=Smith%2C+Luther+A%3BStock%2C+Thomas+H%3BChung%2C+Kuenja+C%3BMukerjee%2C+Shaibal%3BLiao%2C+Xiaojuan+L%3BStallings%2C+Casson%3BAfshar%2C+Masoud&rft.aulast=Smith&rft.aufirst=Luther&rft.date=2007-05-01&rft.volume=128&rft.issue=1-3&rft.spage=369&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-006-9320-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Correlations; Organic compounds in atmosphere; Wind direction; census; traffic; Housing; MTBE; Toluene; community involvement; Volatile organic compounds; USA, Texas; USA, Texas, Houston DO - http://dx.doi.org/10.1007/s10661-006-9320-8 ER - TY - JOUR T1 - The Ecological Condition of Gulf of Mexico Resources from Perdido Key to Port St. Joe, Florida, USA: Part I. Coastal Beach Resources AN - 759321368; 13772018 AB - Using the approach established by EPA's Environmental Monitoring and Assessment Program (EMAP), a shoreline monitoring survey was conducted in August and September 1999, encompassing the Florida Panhandle from Perdido Key, Florida to Port St. Joe, Florida. The objective of this survey was to demonstrate the use of a probabilistic survey for monitoring and estimating the condition of swimmable beach areas. Thirty stations were sampled using a probabilistic sampling design. Hydrographic data were collected in addition to samples for water chemistry. Bacterial indicators, enterococci and fecal coliforms, were enumerated from the water according to the EPA Beaches Environmental Assessment Closure and Health (BEACH) Program and Florida state guidelines. Additional criteria for site condition included the presence or absence of primary and secondary dunes, anthropogenic debris and vegetation. Based on EMAP evaluation guidelines and Florida state criteria, a baseline assessment of the condition of the Gulf of Mexico beach resources surveyed is presented. JF - Environmental Monitoring and Assessment AU - Smith, Lisa M AU - Didonato, Eva M AU - Harwell, Linda C AU - Nestlerode, Janet A AU - Summers, JKevin AD - Gulf Ecology Division, USEPA, 1 Sabine Island Drive, Gulf Breeze, FL, 32561, USA, smith.lisam@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 511 EP - 524 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 128 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Environment Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - dunes KW - Anthropogenic factors KW - Hydrographic data KW - Gulfs KW - Evaluation KW - Baseline studies KW - debris KW - Assessments KW - guidelines KW - Water Chemistry KW - environmental assessment KW - Sampling KW - Environmental monitoring KW - ASW, USA, Florida KW - Beaches KW - Fecal coliforms KW - anthropogenic factors KW - Environmental assessment KW - Surveys KW - Vegetation KW - Fecal Coliforms KW - ASW, Mexico Gulf KW - EPA KW - Ecological conditions KW - Coastal zone KW - Dunes KW - Standards KW - Monitoring KW - Environmental conditions KW - Water chemistry KW - ASW, USA, Florida, Florida Panhandle KW - Q5 08503:Characteristics, behavior and fate KW - M2 551.510.42:Air Pollution (551.510.42) KW - O 4080:Pollution - Control and Prevention KW - P 1000:MARINE POLLUTION KW - SW 3020:Sources and fate of pollution KW - ENA 12:Oceans & Estuaries KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759321368?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=The+Ecological+Condition+of+Gulf+of+Mexico+Resources+from+Perdido+Key+to+Port+St.+Joe%2C+Florida%2C+USA%3A+Part+I.+Coastal+Beach+Resources&rft.au=Smith%2C+Lisa+M%3BDidonato%2C+Eva+M%3BHarwell%2C+Linda+C%3BNestlerode%2C+Janet+A%3BSummers%2C+JKevin&rft.aulast=Smith&rft.aufirst=Lisa&rft.date=2007-05-01&rft.volume=128&rft.issue=1-3&rft.spage=511&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-006-9345-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2014-05-15 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Coastal zone; debris; Baseline studies; Environmental assessment; Water Chemistry; Anthropogenic factors; Fecal Coliforms; Environmental conditions; Ecological conditions; Hydrographic data; Water chemistry; EPA; dunes; Fecal coliforms; Beaches; anthropogenic factors; guidelines; Vegetation; environmental assessment; Evaluation; Assessments; Dunes; Surveys; Standards; Sampling; Monitoring; Gulfs; ASW, Mexico Gulf; ASW, USA, Florida; ASW, USA, Florida, Florida Panhandle DO - http://dx.doi.org/10.1007/s10661-006-9345-z ER - TY - JOUR T1 - AOAC method 966.04: preliminary evaluation of cooked meat medium with manganese sulfate for the cultivation of Clostridium sporogenes: precollaborative study. AN - 70647396; 17580636 AB - AOAC Method 966.04, the Sporicidal Activity of Disinfectants Test, is a carrier-based test that provides a qualitative measure of product efficacy against spores of Bacillus subtilis and Clostridium sporogenes. For regulatory purposes, Method 966.04 is accepted by the U.S. Environmental Protection Agency (EPA) and the U.S. Food and Drug Administration (FDA) for the generation of product performance data for sporicides and sterilants. In this study, we report on findings associated with proposed improvements (modifications) to the Clostridium component of the method. Egg meat medium (EMM), the culture medium for C. sporogenes currently specified in the method, is no longer commercially available and finding a suitable replacement is critical. In addition, the use of a nonstandardized extract of raw soil as an amendment to EMM, as stipulated in the current method, may result in a highly variable spore suspension. The primary focus of this study was to find replacements for EMM and soil extract. A carrier count procedure, the establishment of target carrier counts (spores/carrier), and a neutralization confirmation procedure were also evaluated. The study was limited to liquid products tested against Clostridium on a hard surface carrier (porcelain penicylinder). Spore suspensions of C. sporogenes were generated using: (1) EMM with soil extract (EMM/SE), (2) cooked meat medium with soil extract (CMM/SE), and (3) cooked meat medium with 5 microg/mL manganese sulfate (CMM/MnSO4). The titer of the spore suspension, carrier counts, resistance to hydrochloric acid (HCI), and efficacy against 3 liquid sporicidal agents were used to evaluate the potential of CMM and MnSO4 as replacements. The study was performed by the EPA Office of Pesticide Programs Microbiology Laboratory, Fort Meade, MD. Use of CMM/SE and CMM/MnSO4 resulted in comparable results for titer of spore suspensions (approximately 10(8) spores/mL) and carrier counts (approximately 3 x 10(6) spores/carrier). The carrier counts for the EMM/SE were approximately 1 log lower than CMM-based treatments; however, no attempt was made to dilute the CMM spore suspensions prior to carrier inoculation to reduce the carrier counts for CMM. Resistance of spores to 2.5 M HCI was acceptable across the 3 media types. Treatments for comparative efficacy testing were designed to provide a range of sporicidal activity, i.e., high and low efficacy treatments. Sodium hypochlorite (bleach), hydrogen peroxide/peracetic acid, and glutaraldehyde were used as test chemicals. The number of carriers resulting in growth (positive) for the low treatments for all 3 chemicals ranged from 9 to 59 out of 60 across the 3 media types--EMM exhibited fewer positives overall. The high efficacy treatments for sodium hypochlorite and hydrogen peroxide/peracetic acid yielded a range of 0 to 2 positives out of 60 across the 3 media. However, the high glutaraldehyde treatment generated 3, 20, and 20 positives out of 60 for the EMM/SE, CMM/SE, and CMM/MnSO4, respectively. The lower number of positive carriers for EMM/SE may be due to the reduced carrier counts. CMM, either with SE or MnSO4, appears to be a suitable replacement for EMM/SE. On the basis of the results of this study, the Study Director recommends that CMM/MnSO4 and the spore enumeration target carrier count and neutralization procedures be considered for collaborative study to officially modify the Clostridium x porcelain component of Method 966.04. JF - Journal of AOAC International AU - Tomasino, Stephen F AU - Samalot-Freire, Luisa C AD - U.S. Environmental Protection Agency, Office of Pesticide Programs, Microbiology Laboratory, Environmental Science Center, Fort Meade, MD 20755-5350, USA. tomasino.stephen@epa.gov PY - 2007 SP - 825 EP - 833 VL - 90 IS - 3 SN - 1060-3271, 1060-3271 KW - Disinfectants KW - 0 KW - Manganese Compounds KW - Sulfates KW - Sodium Hypochlorite KW - DY38VHM5OD KW - manganese sulfate KW - W00LYS4T26 KW - Index Medicus KW - United States KW - Soil Microbiology KW - United States Food and Drug Administration KW - United States Environmental Protection Agency KW - Eggs -- microbiology KW - Reproducibility of Results KW - Sodium Hypochlorite -- pharmacology KW - Cooking KW - Bacillus subtilis -- metabolism KW - Disinfectants -- pharmacology KW - Food Analysis -- methods KW - Sulfates -- pharmacology KW - Clostridium -- metabolism KW - Manganese Compounds -- chemistry KW - Food Contamination KW - Meat -- microbiology KW - Sulfates -- chemistry KW - Manganese Compounds -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70647396?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+AOAC+International&rft.atitle=AOAC+method+966.04%3A+preliminary+evaluation+of+cooked+meat+medium+with+manganese+sulfate+for+the+cultivation+of+Clostridium+sporogenes%3A+precollaborative+study.&rft.au=Tomasino%2C+Stephen+F%3BSamalot-Freire%2C+Luisa+C&rft.aulast=Tomasino&rft.aufirst=Stephen&rft.date=2007-05-01&rft.volume=90&rft.issue=3&rft.spage=825&rft.isbn=&rft.btitle=&rft.title=Journal+of+AOAC+International&rft.issn=10603271&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-20 N1 - Date created - 2007-06-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Chronic arsenic exposure and cardiac repolarization abnormalities with QT interval prolongation in a population-based study. AN - 70516914; 17520054 AB - Chronic arsenic exposure is associated with cardiovascular abnormalities. Prolongation of the QT (time between initial deflection of QRS complex to the end of T wave) interval and profound repolarization changes on electrocardiogram (ECG) have been reported in patients with acute promyelocytic leukemia treated with arsenic trioxide. This acquired form of long QT syndrome can result in life-threatening arrhythmias. The objective of this study was to assess the cardiac effects of arsenic by investigating QT interval alterations in a human population chronically exposed to arsenic. Residents in Ba Men, Inner Mongolia, have been chronically exposed to arsenic via consumption of water from artesian wells. A total of 313 Ba Men residents with the mean arsenic exposure of 15 years were divided into three arsenic exposure groups: low ( or = 0.45 sec was considered to be prolonged. The prevalence rates of QT prolongation and water arsenic concentrations showed a dose-dependent relationship (p = 0.001). The prevalence rates of QTc prolongation were 3.9, 11.1, 20.6% for low, medium, and high arsenic exposure, respectively. QTc prolongation was also associated with sex (p < 0.0001) but not age (p = 0.486) or smoking (p = 0.1018). Females were more susceptible to QT prolongation than males. We found significant association between chronic arsenic exposure and QT interval prolongation in a human population. QT interval may potentially be useful in the detection of early cardiac arsenic toxicity. JF - Environmental health perspectives AU - Mumford, Judy L AU - Wu, Kegong AU - Xia, Yajuan AU - Kwok, Richard AU - Yang, Zhihui AU - Foster, James AU - Sanders, William E AD - US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina 27711, USA. mumford.judy@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 690 EP - 694 VL - 115 IS - 5 SN - 0091-6765, 0091-6765 KW - Water Pollutants, Chemical KW - 0 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Heart Rate -- drug effects KW - Electrocardiography -- methods KW - Logistic Models KW - Risk Factors KW - Humans KW - China -- epidemiology KW - Adult KW - Middle Aged KW - Likelihood Functions KW - Male KW - Female KW - Prevalence KW - Arsenic -- analysis KW - Arsenic -- toxicity KW - Water Pollutants, Chemical -- analysis KW - Cardiovascular Abnormalities -- epidemiology KW - Water Pollutants, Chemical -- toxicity KW - Cardiovascular Abnormalities -- chemically induced KW - Environmental Exposure KW - Systole -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70516914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Chronic+arsenic+exposure+and+cardiac+repolarization+abnormalities+with+QT+interval+prolongation+in+a+population-based+study.&rft.au=Mumford%2C+Judy+L%3BWu%2C+Kegong%3BXia%2C+Yajuan%3BKwok%2C+Richard%3BYang%2C+Zhihui%3BFoster%2C+James%3BSanders%2C+William+E&rft.aulast=Mumford&rft.aufirst=Judy&rft.date=2007-05-01&rft.volume=115&rft.issue=5&rft.spage=690&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-02 N1 - Date created - 2007-05-23 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Environ Health Perspect. 2006 Jun;114(6):835-41 [16759981] Nature. 2006 Mar 23;440(7083):463-9 [16554806] Blood. 2001 Mar 1;97(5):1514-6 [11222403] Cell. 2001 Feb 23;104(4):569-80 [11239413] Prog Cardiovasc Dis. 2001 Mar-Apr;43(5 Suppl 1):1-45 [11269621] Blood. 2001 Jul 15;98(2):266-71 [11435292] Tex Heart Inst J. 2001;28(4):265-75 [11777151] Circulation. 2002 Apr 16;105(15):1804-9 [11956123] Leukemia. 2002 Apr;16(4):617-22 [11960341] Int J Cardiol. 2003 Jan;87(1):37-51 [12468053] Cardiovasc Res. 2003 Apr 1;58(1):32-45 [12667944] Environ Mol Mutagen. 2003;42(3):192-205 [14556226] Mol Pharmacol. 2004 Jul;66(1):33-44 [15213294] Toxicol Appl Pharmacol. 2004 Aug 1;198(3):243-52 [15276403] Toxicol Appl Pharmacol. 2004 Aug 1;198(3):272-82 [15276406] Toxicol Appl Pharmacol. 2004 Aug 1;198(3):444-9 [15276425] J Natl Cancer Inst. 1969 Jun;42(6):1045-52 [5797547] J Health Popul Nutr. 2006 Jun;24(2):221-7 [17195563] Am J Dis Child. 1970 Oct;120(4):367-71 [5493839] South Med J. 1989 Dec;82(12):1557-60 [2595426] Pacing Clin Electrophysiol. 1990 Feb;13(2):164-70 [1689832] Cell. 1995 Mar 10;80(5):795-803 [7889573] Cell. 1995 Apr 21;81(2):299-307 [7736582] Nat Genet. 1996 Jan;12(1):17-23 [8528244] Arterioscler Thromb Vasc Biol. 1996 Apr;16(4):504-10 [8624771] Cancer Epidemiol Biomarkers Prev. 1996 Oct;5(10):849-52 [8896897] Circulation. 1996 Nov 15;94(10):2535-41 [8921798] Anal Chem. 1998 May 1;70(9):1926-33 [9599587] JAMA. 1998 Nov 25;280(20):1774-6 [9842954] Biomarkers. 2005 Mar-Jun;10(2-3):95-104 [16076725] Am J Epidemiol. 2005 Dec 1;162(11):1037-49 [16269585] Comment In: Environ Health Perspect. 2007 May;115(5):A262 [17520047] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Using prognostic model-generated meteorological output in the AERMOD dispersion model: an illustrative application in Philadelphia, PA. AN - 70515164; 17518224 AB - In this study, we introduce the prospect of using prognostic model-generated meteorological output as input to steady-state dispersion models by identifying possible advantages and disadvantages and by presenting a comparative analysis. Because output from prognostic meteorological models is now routinely available and is used for Eulerian and Lagrangian air quality modeling applications, we explore the possibility of using such data in lieu of traditional National Weather Service (NWS) data for dispersion models. We apply these data in an urban application where comparisons can be made between the two meteorological input data types. Using the U.S. Environment Protection Agency's American Meteorological Society/U.S. Environmental Protection Agency Regulatory Model (AERMOD) air quality dispersion model, hourly and annual average concentrations of benzene are estimated for the Philadelphia, PA, area using both hourly MM5 model-generated meteorological output and meteorological data taken from the NWS site at the Philadelphia International Airport. Our intent is to stimulate a discussion of the relevant issues and inspire future work that examines many of the questions raised in this paper. JF - Journal of the Air & Waste Management Association (1995) AU - Touma, Jawad S AU - Isakov, Vlad AU - Cimorelli, Alan J AU - Brode, Roger W AU - Anderson, Bret AD - National Oceanic and Atmospheric Administration/Atmospheric Sciences Modeling Division, Research Triangle Park, NC 27711, USA. Touma.Joe@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 586 EP - 595 VL - 57 IS - 5 SN - 1096-2247, 1096-2247 KW - Index Medicus KW - United States KW - Environmental Monitoring KW - United States Environmental Protection Agency KW - Seasons KW - Philadelphia KW - Algorithms KW - Forecasting KW - Wind KW - Models, Theoretical KW - Air Pollution -- statistics & numerical data KW - Meteorological Concepts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70515164?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Using+prognostic+model-generated+meteorological+output+in+the+AERMOD+dispersion+model%3A+an+illustrative+application+in+Philadelphia%2C+PA.&rft.au=Touma%2C+Jawad+S%3BIsakov%2C+Vlad%3BCimorelli%2C+Alan+J%3BBrode%2C+Roger+W%3BAnderson%2C+Bret&rft.aulast=Touma&rft.aufirst=Jawad&rft.date=2007-05-01&rft.volume=57&rft.issue=5&rft.spage=586&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-20 N1 - Date created - 2007-05-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Investigation of a systematic offset in the measurement of organic carbon with a semicontinuous analyzer. AN - 70514240; 17518225 AB - Organic carbon (OC) was measured semicontinuously in laboratory experiments of steady-state secondary organic aerosol formed by hydrocarbon + nitrogen oxide irradiations. Examination of the mass of carbon measured on the filter for various sample volumes reveals a systematic offset that is not observed when performing an instrumental blank. These findings suggest that simple subtraction of instrumental blanks determined as the standard analysis without sample collection (i.e., by cycling the pump and valves yet filtering zero liters of air followed by routine chemical analysis) from measured concentrations may be inadequate. This may be especially true for samples collected through the filtration of small air volumes wherein the influence of the systematic offset is greatest. All of the experiments show that filtering a larger volume of air minimizes the influence of contributions from the systematic offset. Application of these results to measurements of ambient concentrations of carbonaceous aerosol suggests a need for collection of sufficient carbon mass to minimize the relative influence of the offset signal. JF - Journal of the Air & Waste Management Association (1995) AU - Offenberg, John H AU - Lewandowski, Michael AU - Edney, Edward O AU - Kleindienst, Tadeusz E AU - Jaoui, Mohammed AD - U.S. Environmental Protection Agency, National Exposure Research Laboratory, Human Exposure Atmospheric Sciences Division, Research Triangle Park, NC 27711, USA. offenberg.john@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 596 EP - 599 VL - 57 IS - 5 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Hydrocarbons KW - Nitrogen Oxides KW - Carbon KW - 7440-44-0 KW - Index Medicus KW - Photochemistry KW - Hydrocarbons -- chemistry KW - Hydrocarbons -- analysis KW - Filtration KW - Nitrogen Oxides -- chemistry KW - Air -- analysis KW - Nitrogen Oxides -- analysis KW - Carbon -- analysis KW - Air Pollutants -- analysis KW - Carbon -- chemistry KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70514240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Investigation+of+a+systematic+offset+in+the+measurement+of+organic+carbon+with+a+semicontinuous+analyzer.&rft.au=Offenberg%2C+John+H%3BLewandowski%2C+Michael%3BEdney%2C+Edward+O%3BKleindienst%2C+Tadeusz+E%3BJaoui%2C+Mohammed&rft.aulast=Offenberg&rft.aufirst=John&rft.date=2007-05-01&rft.volume=57&rft.issue=5&rft.spage=596&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-20 N1 - Date created - 2007-05-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - If cumulative risk assessment is the answer, what is the question? AN - 70514163; 17520071 AB - Cumulative risk refers to the combined threats from exposure via all relevant routes to multiple stressors including biological, chemical, physical, and psychosocial entities. Cumulative risk assessment is a tool for organizing and analyzing information to examine, characterize, and possibly quantify the combined adverse effects on human health or ecologic resources from multiple environmental stressors. The U.S. Environmental Protection Agency (EPA) has initiated a long-term effort to develop future guidelines for cumulative risk assessment, including publication in 2003 of a framework that describes important features of the process and discusses theoretical issues, technical matters, and key definitions. The framework divides the process of cumulative risk assessment into three interrelated phases: a) planning, scoping, and problem formulation; b) analysis; and c) interpretation and risk characterization. It also discusses the additional complexities introduced by attempts to analyze cumulative risks from multiple stressors and describes some of the theoretical approaches that can be used. The development of guidelines for cumulative risk assessment is an essential element in the transition of the U.S. EPA risk assessment methodology from a narrow focus on a single stressor, end point, source, pathway, and exposure route to a broader, more holistic approach involving analysis of combined effects of cumulative exposure to multiple stressors via all relevant sources, pathways, and routes. JF - Environmental health perspectives AU - Callahan, Michael A AU - Sexton, Ken AD - US Environmental Protection Agency, Region 6, Dallas, Texas 75202-2733, USA. michael@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 799 EP - 806 VL - 115 IS - 5 SN - 0091-6765, 0091-6765 KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - United States KW - United States Environmental Protection Agency KW - Environmental Pollutants -- toxicity KW - Environmental Exposure KW - Guidelines as Topic KW - Risk Assessment -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70514163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=If+cumulative+risk+assessment+is+the+answer%2C+what+is+the+question%3F&rft.au=Callahan%2C+Michael+A%3BSexton%2C+Ken&rft.aulast=Callahan&rft.aufirst=Michael&rft.date=2007-05-01&rft.volume=115&rft.issue=5&rft.spage=799&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-02 N1 - Date created - 2007-05-23 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Risk Anal. 2000 Apr;20(2):273-91 [10859786] Environ Health Perspect. 2007 May;115(5):833-40 [17520075] Environ Health Perspect. 2002 Dec;110 Suppl 6:891-2 [12634115] Environ Health Perspect. 2002 Dec;110 Suppl 6:893-9 [12634116] Int J Occup Med Environ Health. 2004;17(1):103-10 [15212212] J Environ Manage. 2004 Nov;73(2):131-45 [15380318] J Natl Cancer Inst. 1977 May;58(5):1537-41 [853532] Toxicol Lett. 1995 Sep;79(1-3):251-64 [7570663] Regul Toxicol Pharmacol. 1995 Aug;22(1):76-94 [7494906] Toxicology. 1995 Dec 28;105(2-3):307-14 [8571367] Toxicology. 1995 Dec 28;105(2-3):429-41 [8571378] Toxicol Ind Health. 1998 May-Jun;14(3):429-54 [9569448] Radiat Res. 1998 Jul;150(1):58-65 [9650603] Environ Health Perspect. 1998 Dec;106(12):775-92 [9831538] Epidemiology. 1999 Jul;10(4):405-11 [10401875] Regul Toxicol Pharmacol. 2004 Dec;40(3):305-11 [15546684] Environ Health Perspect. 2005 Jan;113(1):43-8 [15626646] Environ Health Perspect. 2005 Apr;113(4):383-90 [15811826] Environ Health Perspect. 2007 May;115(5):807-16 [17520072] Environ Health Perspect. 2007 May;115(5):817-24 [17520073] Environ Health Perspect. 2007 May;115(5):825-32 [17520074] Environ Health Perspect. 2002 Feb;110 Suppl 1:25-42 [11834461] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Detection of changes in alveolar macrophage iron status induced by select PM2.5-associated components using iron-response protein binding activity. AN - 70499582; 17497533 AB - The extent of adverse health effects, including induction/exacerbation of infectious lung disease, arising from entrainment of equivalent amounts (or exposure to a fixed increment) of fine particulate matter (PM2.5) can vary from region to region or city to city in a region. To begin to explain how differing effects on host resistance might arise after exposure to PM2.5 from various sites, we hypothesized that select metals (e.g., V, Al, and Mn) in each PM2.5 caused changes in alveolar macrophage (AM) Fe status that, ultimately, would lead to altered antibacterial function. To test this, iron-response protein (IRP) binding activity in a rat AM cell line was assessed after exposure to Fe alone and in conjunction with V, Mn, and/or Al at ratios of V:Fe, Al:Fe, or Mn:Fe encountered in PM2.5 samples from New York City, Los Angeles, and Seattle. Results indicated that V and Al each significantly altered IRP activity, though effects were not consistently ratio-(i.e., dose-) dependent; Mn had little impact on activity. We conclude that the reductions in Fe status detected here via the IRP assay arose, in part, from effects on transferrin-mediated Fe3+ delivery to the AM. Ongoing studies using this assay are allowing us to better determine: (1) whether mass (and/or molar) relationships between Fe and V, Al, and/or Mn in any PM2.5 sample consistently govern the extent of change in AM Fe status; (2) how much any specified PM2.5 constituent (metal or nonmetal) contributes to the overall disruption of Fe status found induced by an intact parent sample; and (3) whether induced changes in binding activity are relatable to other changes expected to occur in the AM, that is, in IRP-dependent mRNA/levels of ferritin/transferrin receptor and Fe-dependent functions. These studies demonstrate that pollutant-induced effects on lung cell Fe status can be assessed in a reproducible manner using an assay that can be readily performed by investigators who might otherwise have no access to other very costly analytical equipment, such as graphite atomic absorption or x-ray fluorescence spectro(photo)meters. JF - Inhalation toxicology AU - Doherty, S P AU - Prophete, C AU - Maciejczyk, P AU - Salnikow, K AU - Gould, T AU - Larson, T AU - Koenig, J AU - Jaques, P AU - Sioutas, C AU - Zelikoff, J T AU - Lippmann, M AU - Cohen, M D AD - NYU-EPA Particulate Matter Health Research Center, Nelson Institute, New York University School of Medicine Tuxedo, New York 10987, USA. Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 553 EP - 562 VL - 19 IS - 6-7 KW - Air Pollutants KW - 0 KW - Iron-Regulatory Proteins KW - Particulate Matter KW - Iron KW - E1UOL152H7 KW - Index Medicus KW - Rats KW - Protein Binding -- physiology KW - Animals KW - Air Pollutants -- metabolism KW - Protein Binding -- drug effects KW - Air Pollutants -- analysis KW - Cell Line KW - Macrophages, Alveolar -- metabolism KW - Particulate Matter -- metabolism KW - Iron -- pharmacology KW - Iron-Regulatory Proteins -- metabolism KW - Particulate Matter -- analysis KW - Macrophages, Alveolar -- drug effects KW - Iron -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70499582?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inhalation+toxicology&rft.atitle=Detection+of+changes+in+alveolar+macrophage+iron+status+induced+by+select+PM2.5-associated+components+using+iron-response+protein+binding+activity.&rft.au=Doherty%2C+S+P%3BProphete%2C+C%3BMaciejczyk%2C+P%3BSalnikow%2C+K%3BGould%2C+T%3BLarson%2C+T%3BKoenig%2C+J%3BJaques%2C+P%3BSioutas%2C+C%3BZelikoff%2C+J+T%3BLippmann%2C+M%3BCohen%2C+M+D&rft.aulast=Doherty&rft.aufirst=S&rft.date=2007-05-01&rft.volume=19&rft.issue=6-7&rft.spage=553&rft.isbn=&rft.btitle=&rft.title=Inhalation+toxicology&rft.issn=1091-7691&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-27 N1 - Date created - 2007-05-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The cyanobacterial toxin, cylindrospermopsin, induces fetal toxicity in the mouse after exposure late in gestation. AN - 70412925; 17292934 AB - Cylindrospermopsin (cyn) is a cyanobacterial toxin implicated in human and wildlife poisonings. We have completed studies investigating the potential of purified cyn to induce developmental toxicity in mammals. The teratology study involved intraperitoneal injections (8.0-128 microg kg(-1)) on gestational days (GD) 8-12 with subsequent examination of term fetuses for viability, weight and morphological anomalies. Cyn was lethal to a significant portion of the dams receiving > or = 32 microg kg(-1). Surviving pregnant females were killed and fetuses removed for examination. Analysis indicates no adverse effects on litter size, fetal weight, or incidence of anomalies. Subsequently, 50 microg kg(-1) cyn was administered on GD 8-12 or 13-17. Animals were allowed to give birth and litters monitored for growth and viability. A reduction in litter size occurred in treated groups. Avg. pup wt. was only affected in the GD 13-17 group. GD 13-17 dams did not exhibit the toxicity noted in the GD 8-12 group but gave birth significantly earlier than controls. There was a significant number of dead GD 13-17 pups and incidences of blood in the gastrointestinal tract and hematomas in the tips of the tails in survivors. Pups were cross-fostered to control mothers in litters of 10. On postnatal days (PND) 5-6 there were no significant differences in weight gain or viability in GD 8-12 litters, while GD 13-17 litters had significantly reduced weight gain and viability. GD 13-17 exposed male pups still weighed significantly less than the controls after 15 months. JF - Toxicon : official journal of the International Society on Toxinology AU - Rogers, E H AU - Zehr, R D AU - Gage, M I AU - Humpage, A R AU - Falconer, I R AU - Marr, M AU - Chernoff, N AD - US EPA, ORD, National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC 27711, USA. Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 855 EP - 864 VL - 49 IS - 6 SN - 0041-0101, 0041-0101 KW - Bacterial Toxins KW - 0 KW - Marine Toxins KW - Microcystins KW - cyanobacterial toxin KW - cylindrospermopsin KW - 2JIZ556BA3 KW - Uracil KW - 56HH86ZVCT KW - Index Medicus KW - Injections, Intraperitoneal KW - Animals, Newborn KW - Animals KW - Fetus -- drug effects KW - Gestational Age KW - Mice KW - Embryo, Mammalian -- drug effects KW - Male KW - Female KW - Prenatal Exposure Delayed Effects KW - Pregnancy KW - Cyanobacteria KW - Uracil -- analogs & derivatives KW - Uracil -- administration & dosage KW - Marine Toxins -- administration & dosage KW - Microcystins -- toxicity KW - Microcystins -- administration & dosage KW - Bacterial Toxins -- toxicity KW - Uracil -- toxicity KW - Bacterial Toxins -- administration & dosage KW - Marine Toxins -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70412925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.atitle=The+cyanobacterial+toxin%2C+cylindrospermopsin%2C+induces+fetal+toxicity+in+the+mouse+after+exposure+late+in+gestation.&rft.au=Rogers%2C+E+H%3BZehr%2C+R+D%3BGage%2C+M+I%3BHumpage%2C+A+R%3BFalconer%2C+I+R%3BMarr%2C+M%3BChernoff%2C+N&rft.aulast=Rogers&rft.aufirst=E&rft.date=2007-05-01&rft.volume=49&rft.issue=6&rft.spage=855&rft.isbn=&rft.btitle=&rft.title=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.issn=00410101&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-20 N1 - Date created - 2007-04-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Gender-based differences in endocrine and reproductive toxicity. AN - 70385665; 17157289 AB - Basic differences in male versus female reproductive physiology lead to differentials in their respective susceptibilities to chemical insult as evidenced by a variety of observations. As individuals undergo maturation from prenatal sex differentiation through pubertal development, these susceptibilities become evident in each gender. Gender bias occurs in human populations for birth defects and for the acceleration of the onset of puberty. Data on gender bias in fetal origins of adult disease are more complex. Useful for understanding reproductive and developmental effects in animals are a range of standard methodological procedures including the multigeneration testing protocol and the National Toxicology Program (NTP) Reproductive Assessment by Continuous Breeding (RACB). Examples of gender-based differences seen in reproductive toxicology studies on animals include teratogenic effects, reproductive effects in adult males and females, and effects on pubertal development. It is clear that gender biases exist in the reproductive and developmental toxicity, and the biological bases for these differences need to be explored. JF - Environmental research AU - Cummings, Audrey M AU - Stoker, Tammy AU - Kavlock, Robert J AD - Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, United States Environmental Protection Agency, USA. cummings.audrey@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 96 EP - 107 VL - 104 IS - 1 SN - 0013-9351, 0013-9351 KW - Hazardous Substances KW - 0 KW - Index Medicus KW - Animals KW - Age Factors KW - Humans KW - Toxicology -- methods KW - Male KW - Female KW - Pregnancy KW - Reproduction -- physiology KW - Endocrine System -- physiology KW - Sex Characteristics KW - Reproduction -- drug effects KW - Environmental Exposure KW - Endocrine System -- drug effects KW - Hazardous Substances -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70385665?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+research&rft.atitle=Gender-based+differences+in+endocrine+and+reproductive+toxicity.&rft.au=Cummings%2C+Audrey+M%3BStoker%2C+Tammy%3BKavlock%2C+Robert+J&rft.aulast=Cummings&rft.aufirst=Audrey&rft.date=2007-05-01&rft.volume=104&rft.issue=1&rft.spage=96&rft.isbn=&rft.btitle=&rft.title=Environmental+research&rft.issn=00139351&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-11-21 N1 - Date created - 2007-04-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Evaluation of physiologically based pharmacokinetic models for use in risk assessment. AN - 70372554; 17299829 AB - Physiologically based pharmacokinetic (PBPK) models are sophisticated dosimetry models that offer great flexibility in modeling exposure scenarios for which there are limited data. This is particularly of relevance to assessing human exposure to environmental toxicants, which often requires a number of extrapolations across species, route, or dose levels. The continued development of PBPK models ensures that regulatory agencies will increasingly experience the need to evaluate available models for their application in risk assessment. To date, there are few published criteria or well-defined standards for evaluating these models. Herein, important considerations for evaluating such models are described. The evaluation of PBPK models intended for risk assessment applications should include a consideration of: model purpose, model structure, mathematical representation, parameter estimation, computer implementation, predictive capacity and statistical analyses. Model purpose and structure require qualitative checks on the biological plausibility of a model. Mathematical representation, parameter estimation, computer implementation involve an assessment of the coding of the model, as well as the selection and justification of the physical, physicochemical and biochemical parameters chosen to represent a biological organism. Finally, the predictive capacity and sensitivity, variability and uncertainty of the model are analysed so that the applicability of a model for risk assessment can be determined. Published in 2007 by John Wiley & Sons, Ltd. JF - Journal of applied toxicology : JAT AU - Chiu, Weihsueh A AU - Barton, Hugh A AU - DeWoskin, Robert S AU - Schlosser, Paul AU - Thompson, Chad M AU - Sonawane, Babasaheb AU - Lipscomb, John C AU - Krishnan, Kannan AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW, Washington, DC 20460, USA. PY - 2007 SP - 218 EP - 237 VL - 27 IS - 3 SN - 0260-437X, 0260-437X KW - Hazardous Substances KW - 0 KW - Index Medicus KW - Animals KW - Computer Simulation KW - Reproducibility of Results KW - Humans KW - Monitoring, Physiologic -- methods KW - Algorithms KW - Risk Assessment -- methods KW - Hazardous Substances -- pharmacokinetics KW - Models, Biological UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70372554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+applied+toxicology+%3A+JAT&rft.atitle=Evaluation+of+physiologically+based+pharmacokinetic+models+for+use+in+risk+assessment.&rft.au=Chiu%2C+Weihsueh+A%3BBarton%2C+Hugh+A%3BDeWoskin%2C+Robert+S%3BSchlosser%2C+Paul%3BThompson%2C+Chad+M%3BSonawane%2C+Babasaheb%3BLipscomb%2C+John+C%3BKrishnan%2C+Kannan&rft.aulast=Chiu&rft.aufirst=Weihsueh&rft.date=2007-05-01&rft.volume=27&rft.issue=3&rft.spage=218&rft.isbn=&rft.btitle=&rft.title=Journal+of+applied+toxicology+%3A+JAT&rft.issn=0260437X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-09 N1 - Date created - 2007-04-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Pollution abatement activities and traditional productivity AN - 36610817; 3396792 AB - This study models the joint production of good and bad output production and calculates traditional productivity when bad output production is regulated and when it is unregulated. We apply this model to data for U.S. coal-fired electric power plants for 1985-1995 and compare rates of productivity and technical change to gain an understanding of the association between pollution abatement activities and traditional rates of productivity and technical change. While traditional productivity and technical change associated with abatement activities decline, we conclude they are not statistically significant. All rights reserved, Elsevier JF - Ecological economics AU - Fare, R AU - Grosskopf, S AU - Pasurka, Carl A AD - US Environmental Protection Agency Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 673 EP - 682 VL - 62 IS - 3-4 SN - 0921-8009, 0921-8009 KW - Economics KW - Environmental economics KW - Coal KW - U.S.A. KW - Technological change KW - Productivity KW - Electric power plants KW - Pollution KW - Modelling UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36610817?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+economics&rft.atitle=Pollution+abatement+activities+and+traditional+productivity&rft.au=Fare%2C+R%3BGrosskopf%2C+S%3BPasurka%2C+Carl+A&rft.aulast=Fare&rft.aufirst=R&rft.date=2007-05-01&rft.volume=62&rft.issue=3-4&rft.spage=673&rft.isbn=&rft.btitle=&rft.title=Ecological+economics&rft.issn=09218009&rft_id=info:doi/10.1016%2Fj.ecolecon.2006.08.014 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 9818; 4157; 4316 4025; 2412 5255 5336 4246; 12616 12622; 8162 8163; 10280; 433 293 14 DO - http://dx.doi.org/10.1016/j.ecolecon.2006.08.014 ER - TY - JOUR T1 - Biodegradability of dispersed crude oil at two different temperatures AN - 20851169; 7498662 AB - Laboratory experiments were initiated to study the biodegradability of oil after dispersants were applied. Two experiments were conducted, one at 20 super(o)C and the other at 5 super(o)C. In both experiments, only the dispersed oil fraction was investigated. Each experiment required treatment flasks containing 3.5% artificial seawater and crude oil previously dispersed by either Corexit 9500 or JD2000 at a dispersant-to-oil ratio of 1:25. Two different concentrations of dispersed oil were prepared, the dispersed oil then transferred to shake flasks, which were inoculated with a bacterial culture and shaken on a rotary shaker at 200rpm for several weeks. Periodically, triplicate flasks were removed and sacrificed to determine the residual oil concentration remaining at that time. Oil compositional analysis was performed by gas chromatography/mass spectrometry (GC/MS) to quantify the biodegradability. Dispersed oil biodegraded rapidly at 20 super(o)C and less rapidly at 5 super(o)C, in line with the hypothesis that the ultimate fate of dispersed oil in the sea is rapid loss by biodegradation. JF - Marine Pollution Bulletin AU - Venosa, AD AU - Holder, EL AD - 26 W. Martin Luther King Drive, Cincinnati, OH 45268, United States, venosa.albert@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 545 EP - 553 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 54 IS - 5 SN - 0025-326X, 0025-326X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Water Resources Abstracts; Pollution Abstracts; Sustainability Science Abstracts KW - Mass Spectrometry KW - Water Pollution KW - Biodegradation KW - Seawater KW - Mass spectrometry KW - Cell culture KW - Mass spectroscopy KW - Oil KW - Crude oil KW - Marine environment KW - Gas chromatography KW - Oil pollution KW - Oil Pollution KW - Oil spills KW - Laboratory Equipment KW - Temperature effects KW - Marine KW - Laboratory testing KW - Laboratories KW - Temperature KW - Dispersants KW - Biodegradability KW - Marine pollution KW - Analytical Methods KW - Cultures KW - Artificial seawater KW - artificial seawater KW - Q5 08503:Characteristics, behavior and fate KW - M3 1010:Issues in Sustainable Development KW - SW 3020:Sources and fate of pollution KW - P 1000:MARINE POLLUTION KW - A 01320:Microbial Degradation KW - AQ 00004:Water Treatment KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20851169?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Pollution+Bulletin&rft.atitle=Biodegradability+of+dispersed+crude+oil+at+two+different+temperatures&rft.au=Venosa%2C+AD%3BHolder%2C+EL&rft.aulast=Venosa&rft.aufirst=AD&rft.date=2007-05-01&rft.volume=54&rft.issue=5&rft.spage=545&rft.isbn=&rft.btitle=&rft.title=Marine+Pollution+Bulletin&rft.issn=0025326X&rft_id=info:doi/10.1016%2Fj.marpolbul.2006.12.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Biodegradation; Crude oil; Marine pollution; Oil pollution; Dispersants; Artificial seawater; Oil spills; Oil; Gas chromatography; Marine environment; Cell culture; Biodegradability; Mass spectroscopy; Laboratory testing; Temperature; Mass spectrometry; artificial seawater; Water Pollution; Mass Spectrometry; Analytical Methods; Laboratories; Seawater; Cultures; Oil Pollution; Laboratory Equipment; Marine DO - http://dx.doi.org/10.1016/j.marpolbul.2006.12.013 ER - TY - JOUR T1 - A Structured Approach for Developing Indices of Biotic Integrity: Three Examples from Streams and Rivers in the Western USA AN - 20538640; 9225318 AB - In the late 1990s the Environmental Monitoring and Assessment Program of the U.S. Environmental Protection Agency developed a structured set of tests to evaluate and facilitate selection of metrics for indices of biotic integrity (IBIs). These IBIs were designed to be applicable across multistate regions as part of a national assessment of all U.S. waters. Here, we present additional steps in, and refinements to, that IBI development process. We used fish and amphibian assemblage data from 932 stream and river sites in 12 western U.S. states to develop IBIs for Mountains, Xeric, and Plains ecoregions. We divided 237 candidate metrics into nine metric classes representing different attributes of assemblage structure and function. For each ecoregion we sequentially eliminated metrics by testing metric range, signal-to-noise ratios, responsiveness to disturbance, and redundancy to select the best metric in each class. The IBIs for the Mountains and Plains each had seven metrics and the Xeric IBI had five. In the Mountains, half of the estimated stream length that could be assessed had IBI scores greater than 62 (out of 100). In the Xeric and Plains, half the stream length had scores no greater than 50 and no greater than 37, respectively. An estimated 16% of Xeric stream length had scores greater than 62 (the median for the Mountains), while 5% of Plains stream length had scores that exceeded 62. This IBI development process is less subjective and more streamlined and has more clearly defined criteria for metric selection and scoring than those used in the past, while maintaining a strong ecological foundation. JF - Transactions of the American Fisheries Society AU - Whittier, Thomas R AU - Hughes, Robert M AU - Stoddard, John L AU - Lomnicky, Gregg A AU - Peck, David V AU - Herlihy, Alan T AD - Department of Fisheries and Wildlife, Oregon State University, 200 Southwest 35th Street, Corvallis, Oregon 97333, USA, whittier.thom@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 718 EP - 735 PB - American Fisheries Society, 5410 Grosvenor Ln. VL - 136 IS - 3 SN - 0002-8487, 0002-8487 KW - Pollution Abstracts; Ecology Abstracts; Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Amphibiotic species KW - Development KW - Freshwater KW - Streams KW - Mountains KW - foundations KW - Structure-function relationships KW - plains KW - Environmental monitoring KW - Rivers KW - disturbance KW - Biological development KW - Data processing KW - amphibians KW - Environmental protection KW - EPA KW - USA KW - Community composition KW - Signal-to-noise ratio KW - Fish KW - Q1 08342:Geographical distribution KW - D 04070:Pollution KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20538640?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Transactions+of+the+American+Fisheries+Society&rft.atitle=A+Structured+Approach+for+Developing+Indices+of+Biotic+Integrity%3A+Three+Examples+from+Streams+and+Rivers+in+the+Western+USA&rft.au=Whittier%2C+Thomas+R%3BHughes%2C+Robert+M%3BStoddard%2C+John+L%3BLomnicky%2C+Gregg+A%3BPeck%2C+David+V%3BHerlihy%2C+Alan+T&rft.aulast=Whittier&rft.aufirst=Thomas&rft.date=2007-05-01&rft.volume=136&rft.issue=3&rft.spage=718&rft.isbn=&rft.btitle=&rft.title=Transactions+of+the+American+Fisheries+Society&rft.issn=00028487&rft_id=info:doi/10.1577%2FT06-128.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Rivers; Environmental monitoring; Community composition; Biological development; Signal-to-noise ratio; Amphibiotic species; Environmental protection; Mountains; Data processing; Structure-function relationships; Development; Streams; EPA; disturbance; foundations; Fish; plains; amphibians; USA; Freshwater DO - http://dx.doi.org/10.1577/T06-128.1 ER - TY - JOUR T1 - The Cycle of Emerging Contaminants AN - 20350635; 9026707 AB - An overview of the sources of contaminants of emerging concern (ECs). The author focuses on how wastewater and drinking water treatments affect ECs occurrence, transport, and fate in the environment. JF - Water Resources Impact AU - Glassmeyer, ST Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 5 VL - 9 IS - 3 SN - 1522-3175, 1522-3175 KW - Aqualine Abstracts; Pollution Abstracts; Environment Abstracts KW - Drinking Water KW - Pollutants KW - Water Treatment KW - Contaminants KW - Drinking water KW - Wastewater KW - P 2000:FRESHWATER POLLUTION KW - AQ 00002:Water Quality KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20350635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=39th+Annual+Meeting+of+the+Society+for+the+Study+of+Reproduction&rft.atitle=Effects+of+Gestational+and+Lactational+Exposure+to+Ethinyl+Estradiol+and+Bisphenol+a+on+Reproductive+Physiology+and+Serum+Steroid+Hormones+in+the+Male+Long+Evans+Hooded+Rat&rft.au=Howdeshell%2C+Kembra+L%3BFurr%2C+Johnathan%3BLambright%2C+Christy+R%3BWilson%2C+Vickie+S%3BRyan%2C+Bryce+C%3BVandenbergh%2C+John+G%3BGray+Jr%2C+L+Earl&rft.aulast=Howdeshell&rft.aufirst=Kembra&rft.date=2006-07-28&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=39th+Annual+Meeting+of+the+Society+for+the+Study+of+Reproduction&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Drinking water; Contaminants; Wastewater; Drinking Water; Pollutants; Water Treatment ER - TY - JOUR T1 - The impact of marine reserves on nekton diversity and community composition in subtropical eastern Australia AN - 20294573; 7483425 AB - The effectiveness of marine reserve protection on the biodiversity of aquatic assemblages (i.e. nekton) in subtropical eastern Australia was examined within two small (<6km super(2)) marine reserves and four non-reserve areas. The two marine reserves, and their corresponding non-reserves, were located in different geographical locations within Moreton Bay (north and south) and sites were surveyed with multiple hauls of a seine net. Species richness, evenness, density and mean size of the inshore communities were compared between the reserves and non-reserves. No statistical significant difference was detected in species richness between the areas however species evenness was significantly lower in the only non-reserve site impacted by commercial net fishing. Mean size of nekton was found to be significantly greater in the marine reserves compared to non-reserves but no statistical significant difference was found in the density of nekton between the study sites. Multivariate analysis revealed differences in community composition, particularly between the geographical locations where areas were impacted by different types of fishing pressure (recreational v commercial). These results highlight the impact commercial fishing can have on entire nekton assemblages, not just on targeted species. Our study demonstrates that the small marine reserves in Moreton Bay are protecting marine biodiversity and are thus at least partially achieving their management objective (to enhance the zone's marine biodiversity). JF - Biological Conservation AU - Pillans, S AU - Ortiz, J C AU - Pillans, R D AU - Possingham, H P AD - Estuary and Waterway Management, Australia, sue.pillans@epa.qld.gov.au Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 455 EP - 469 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl] VL - 136 IS - 3 SN - 0006-3207, 0006-3207 KW - Sustainability Science Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Marine KW - Geographical distribution KW - Stock assessment KW - Statistical analysis KW - Biodiversity KW - Catch/effort KW - Nekton KW - Community composition KW - Fishery management KW - ISEW, Australia, Queensland, Moreton Bay KW - Fishery surveys KW - Marine parks KW - Nature conservation KW - Conservation KW - Pressure KW - Species richness KW - Q5 08523:Conservation, wildlife management and recreation KW - M3 1010:Issues in Sustainable Development KW - Q1 08604:Stock assessment and management KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20294573?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Conservation&rft.atitle=The+impact+of+marine+reserves+on+nekton+diversity+and+community+composition+in+subtropical+eastern+Australia&rft.au=Pillans%2C+S%3BOrtiz%2C+J+C%3BPillans%2C+R+D%3BPossingham%2C+H+P&rft.aulast=Pillans&rft.aufirst=S&rft.date=2007-05-01&rft.volume=136&rft.issue=3&rft.spage=455&rft.isbn=&rft.btitle=&rft.title=Biological+Conservation&rft.issn=00063207&rft_id=info:doi/10.1016%2Fj.biocon.2006.12.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Community composition; Fishery management; Fishery surveys; Stock assessment; Nature conservation; Marine parks; Biodiversity; Catch/effort; Nekton; Geographical distribution; Statistical analysis; Conservation; Pressure; Species richness; ISEW, Australia, Queensland, Moreton Bay; Marine DO - http://dx.doi.org/10.1016/j.biocon.2006.12.018 ER - TY - JOUR T1 - Synchroton X-ray absorption-edge computed microtograpy imaging of thallium compartmentalization in Iberis intermedia AN - 20294237; 7467514 JF - Plant and Soil AU - Scheckel, Kirk G AU - Hamon, Rebecca AU - Jassongne, Laurence AU - Rivers, Mark AU - Lombi, Enzo AD - ORD, NRMRL, LRPCD, US EPA, 5995 Center Hill Avenue, Cincinnati, OH, 45224, USA, Scheckel.Kirk@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 305 EP - 306 PB - Springer-Verlag (Heidelberg), Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 294 IS - 1-2 SN - 0032-079X, 0032-079X KW - Ecology Abstracts KW - Thallium KW - imaging KW - Iberis KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20294237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+and+Soil&rft.atitle=Synchroton+X-ray+absorption-edge+computed+microtograpy+imaging+of+thallium+compartmentalization+in+Iberis+intermedia&rft.au=Scheckel%2C+Kirk+G%3BHamon%2C+Rebecca%3BJassongne%2C+Laurence%3BRivers%2C+Mark%3BLombi%2C+Enzo&rft.aulast=Scheckel&rft.aufirst=Kirk&rft.date=2007-05-01&rft.volume=294&rft.issue=1-2&rft.spage=305&rft.isbn=&rft.btitle=&rft.title=Plant+and+Soil&rft.issn=0032079X&rft_id=info:doi/10.1007%2Fs11104-007-9257-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Iberis; imaging; Thallium DO - http://dx.doi.org/10.1007/s11104-007-9257-x ER - TY - JOUR T1 - Evaluation of Blast Furnace Slag as a Means of Reducing Metal Availability in a Contaminated Sediment for Beneficial Use Purposes AN - 20276445; 8883110 AB - An attractive option for the management of dredged sediment involves the use of dredged sediment for beneficial use purposes, such as for fill material. Treatment (chemical amendment) of contaminated sediment may be necessary to limit the environmental and human availability (bioaccessibility, leachability, plant uptake) of heavy metals associated with the contaminated sediment before it is placed. A laboratory study was conducted to investigate the effect of admixing a specific chemical amendment (blast furnace slag) with slightly contaminated fresh-water sediment for reducing metal availability. Initial characterization tests of the un-amended sediment showed that the some of the metals analyzed were present in relatively available (non-residual) forms. Although sulfide was present in the un-amended sediment, the amount was not sufficient to bind all of the available metals. A series of metal availability testing methods indicated that the amendment of the sediment with blast furnace slag (4% on a dry weight ratio basis) had the potential to slightly reduce the availability of some, but not all of the available metals associated with the sediment. Results of the column and batch leaching tests showed that leachability of certain metals, such as barium, nickel and zinc, was reduced by the amendment, but the leachability of copper increased. The effect of the amendment for decreasing bioaccessibility for lead and arsenic was not demonstrated. The amended soil had a detrimental effect on most of the plant species that were evaluated. The metal availability results for the plant uptake tests were also mixed, with slightly lower uptake of certain metals by corn grown within the amended sediment. JF - Soil and Sediment Contamination AU - Barth, Ed AU - Sass, Bruce AU - Chattopadhyay, Sandip AD - NRMRL, ORD, US EPA, Cincinnati, Ohio, USA Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 281 EP - 300 PB - CRC Press LLC, 2000 Corporate Blvd., NW Boca Raton FL 33431 USA, [mailto:journals@crcpress.com] VL - 16 IS - 3 SN - 1532-0383, 1532-0383 KW - Pollution Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Heavy metals KW - Nickel KW - Copper KW - Beneficial Use KW - Environmental factors KW - corn KW - Lead KW - Soil KW - Sulphides KW - Zinc KW - Absorption KW - soil amendment KW - Sediment Contamination KW - Chemical pollution KW - heavy metals KW - Testing Procedures KW - Metals KW - Sediment pollution KW - Sediment chemistry KW - Arsenic KW - Leaching KW - Sulfides KW - Sediments KW - Barium KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution KW - Q2 09183:Physics and chemistry KW - Q5 08505:Prevention and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20276445?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Soil+and+Sediment+Contamination&rft.atitle=Evaluation+of+Blast+Furnace+Slag+as+a+Means+of+Reducing+Metal+Availability+in+a+Contaminated+Sediment+for+Beneficial+Use+Purposes&rft.au=Barth%2C+Ed%3BSass%2C+Bruce%3BChattopadhyay%2C+Sandip&rft.aulast=Barth&rft.aufirst=Ed&rft.date=2007-05-01&rft.volume=16&rft.issue=3&rft.spage=281&rft.isbn=&rft.btitle=&rft.title=Soil+and+Sediment+Contamination&rft.issn=15320383&rft_id=info:doi/10.1080%2F15320380701285683 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Sulphides; Sediment chemistry; Sediment pollution; Arsenic; Leaching; Heavy metals; Barium; Nickel; Chemical pollution; Environmental factors; Lead; Metals; Sulfides; Copper; corn; Soil; Zinc; soil amendment; heavy metals; Testing Procedures; Absorption; Sediment Contamination; Beneficial Use; Sediments DO - http://dx.doi.org/10.1080/15320380701285683 ER - TY - JOUR T1 - Summer Fish Community of the Coastal Northern Gulf of Mexico: Characterization of a Large-Scale Trawl Survey AN - 20193815; 7474239 AB - Fish were collected by otter trawl at 367 sites from 119 coastal water bodies in the northern Gulf of Mexico, ranging from north-central Florida to the Rio Grande, Texas, during the summer months of 1992-1994. The fish were identified and enumerated, and tissue contaminants (in fillets), and external abnormalities (body, buccal, branchial, and ocular) were determined. Results were compared for sites east and west of the Mississippi River, within the Mississippi River, seven estuarine categories, and over 3 years. Approximately 31,000 individual fish were captured, representing 100 genera and 141 species. Thirteen species comprised 91% of the total abundance; abundances of 128 species were 1% or less. Pinfish Lagodon rhomboides, Atlantic croaker Micropogonias undulatus, Gulf menhaden Brevoortia patronus, and bay anchovy Anchoa mitchilli were the more dominant species. Fourteen species were collected from at least 10% of the sites; 85 species were captured at no more than 1% of the sites. Atlantic croakers and hardhead catfish Ariopsis felis were collected more frequently (>50% of sites). Indices of community structure from the full data set ranged as follows: 2.8 for the Shannon-Wiener index, 0.90 for Simpsons index, and 0.56 for Pielous evenness index. Chemical contaminants (predominantly total mercury and polychlorinated biphenyls [PCBs]) exceeded federal risk-based consumption guidelines in 2.7% of fillets from four species. External abnormalities occurred on 17 species and approximately 1% of the total number of fish examined. Community structural properties varied temporally across years and spatially over estuarine categories and between areas east and west of the Mississippi River. Four distinct assemblages were identified by cluster analysis of species abundance. Cluster membership was associated with salinity, depth, dissolved oxygen, water clarity, and geographic area. JF - Transactions of the American Fisheries Society AU - Lewis, Michael AU - Jordan, Stephen AU - Chancy, Cynthia AU - Harwell, Linda AU - Goodman, Larry AU - Quarles, Robert AD - U.S. Environmental Protection Agency, Office of Research and Development, 1 Sabine Island Drive, Gulf Breeze, Florida 32561, USA Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 829 EP - 845 PB - American Fisheries Society, 5410 Grosvenor Ln. Ste. 110 Bethesda MD 20814-2199 USA VL - 136 IS - 5 SN - 0002-8487, 0002-8487 KW - Ecology Abstracts; Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Sustainability Science Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Abundance KW - Micropogonias undulatus KW - Brevoortia patronus KW - Dissolved oxygen KW - Marine fish KW - ASW, USA, Texas KW - Lagodon rhomboides KW - Salinity KW - guidelines KW - Brackishwater environment KW - Chemical pollution KW - Seafood KW - Fish fillets KW - PCB compounds KW - PCB KW - Rivers KW - Marine KW - ASW, USA, Florida KW - Anchoa mitchilli KW - Felis KW - dominant species KW - Estuaries KW - Brackish KW - Coastal waters KW - ASW, Mexico Gulf KW - Dominant species KW - North America, Mississippi R. KW - Community composition KW - polychlorinated biphenyls KW - Community structure KW - summer KW - Mercury KW - Fish KW - Contaminants KW - Abnormalities KW - abundance KW - Q1 08345:Genetics and evolution KW - M3 1010:Issues in Sustainable Development KW - P 1000:MARINE POLLUTION KW - D 04040:Ecosystem and Ecology Studies KW - Q5 08504:Effects on organisms KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20193815?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Transactions+of+the+American+Fisheries+Society&rft.atitle=Summer+Fish+Community+of+the+Coastal+Northern+Gulf+of+Mexico%3A+Characterization+of+a+Large-Scale+Trawl+Survey&rft.au=Lewis%2C+Michael%3BJordan%2C+Stephen%3BChancy%2C+Cynthia%3BHarwell%2C+Linda%3BGoodman%2C+Larry%3BQuarles%2C+Robert&rft.aulast=Lewis&rft.aufirst=Michael&rft.date=2007-05-01&rft.volume=136&rft.issue=5&rft.spage=829&rft.isbn=&rft.btitle=&rft.title=Transactions+of+the+American+Fisheries+Society&rft.issn=00028487&rft_id=info:doi/10.1577%2FT06-077.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2014-05-05 N1 - SubjectsTermNotLitGenreText - Marine fish; Dominant species; Community composition; Estuaries; Brackishwater environment; Seafood; Fish fillets; PCB; Abnormalities; Rivers; polychlorinated biphenyls; Community structure; Abundance; Contaminants; Dissolved oxygen; Salinity; guidelines; dominant species; Mercury; summer; Fish; Chemical pollution; Coastal waters; PCB compounds; abundance; Lagodon rhomboides; Felis; Anchoa mitchilli; Micropogonias undulatus; Brevoortia patronus; ASW, Mexico Gulf; ASW, USA, Texas; ASW, USA, Florida; North America, Mississippi R.; Marine; Brackish DO - http://dx.doi.org/10.1577/T06-077.1 ER - TY - JOUR T1 - Significant Beach Nourishment Project Underway At Dauphin Island, Alabama (U.S.A.) AN - 19981085; 7595110 JF - Journal of Coastal Research AU - Froede, C R AD - United States Environmental Protection Agency, Region 4, 61 Forsyth Street, Atlanta, GA 30303-8960 Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 807 EP - 808 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 23 IS - 3 SN - 0749-0208, 0749-0208 KW - Pollution Abstracts; Sustainability Science Abstracts; Water Resources Abstracts; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Beaches KW - ASW, USA, Alabama, Dauphin I. KW - Coastal erosion KW - USA, Alabama, Dauphin I. KW - Shores KW - Environmental protection KW - Islands KW - Coastal morphology KW - Beach nourishment KW - Coasts KW - Q2 09271:Coastal morphology KW - M3 1010:Issues in Sustainable Development KW - P 1000:MARINE POLLUTION KW - SW 0870:Erosion and sedimentation KW - O 3050:Sediment Dynamics KW - Q5 08522:Protective measures and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19981085?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Coastal+Research&rft.atitle=Significant+Beach+Nourishment+Project+Underway+At+Dauphin+Island%2C+Alabama+%28U.S.A.%29&rft.au=Froede%2C+C+R&rft.aulast=Froede&rft.aufirst=C&rft.date=2007-05-01&rft.volume=23&rft.issue=3&rft.spage=807&rft.isbn=&rft.btitle=&rft.title=Journal+of+Coastal+Research&rft.issn=07490208&rft_id=info:doi/10.2112%2F1551-5036%282007%29232.0.CO%3B2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Coastal erosion; Beach nourishment; Coastal morphology; Environmental protection; Coasts; Beaches; Islands; Shores; ASW, USA, Alabama, Dauphin I.; USA, Alabama, Dauphin I. DO - http://dx.doi.org/10.2112/1551-5036(2007)23[807:SBNPUA]2.0.CO;2 ER - TY - JOUR T1 - The Microbial Community Structure in Petroleum-Contaminated Sediments Corresponds to Geophysical Signatures AN - 19978776; 7403322 AB - The interdependence between geoelectrical signatures at underground petroleum plumes and the structures of subsurface microbial communities was investigated. For sediments contaminated with light non-aqueous-phase liquids, anomalous high conductivity values have been observed. Vertical changes in the geoelectrical properties of the sediments were concomitant with significant changes in the microbial community structures as determined by the construction and evaluation of 16S rRNA gene libraries. DNA sequencing of clones from four 16S rRNA gene libraries from different depths of a contaminated field site and two libraries from an uncontaminated background site revealed spatial heterogeneity in the microbial community structures. Correspondence analysis showed that the presence of distinct microbial populations, including the various hydrocarbon-degrading, syntrophic, sulfate-reducing, and dissimilatory-iron-reducing populations, was a contributing factor to the elevated geoelectrical measurements. Thus, through their growth and metabolic activities, microbial populations that have adapted to the use of petroleum as a carbon source can strongly influence their geophysical surroundings. Since changes in the geophysical properties of contaminated sediments parallel changes in the microbial community compositions, it is suggested that geoelectrical measurements can be a cost-efficient tool to guide microbiological sampling for microbial ecology studies during the monitoring of natural or engineered bioremediation processes. JF - Applied and Environmental Microbiology AU - Allen, Jonathan P AU - Atekwana, Estella A AU - Atekwana, Eliot A AU - Duris, Joseph W AU - Werkema, DDale AU - Rossbach, Silvia AD - Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan 49008-5410. T. Boone Pickens School of Geology, Oklahoma State University, 105 Noble Research Center, Stillwater, Oklahoma 74078-3031. Characterization and Monitoring Branch, Environmental Sciences Division, National Exposure Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Las Vegas, Nevada 89119 PY - 2007 SP - 2860 EP - 2870 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 73 IS - 9 SN - 0099-2240, 0099-2240 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts A: Industrial & Applied Microbiology; Pollution Abstracts; Water Resources Abstracts; Microbiology Abstracts B: Bacteriology; Aqualine Abstracts; Ecology Abstracts KW - Bioremediation KW - Libraries KW - Petroleum KW - Sediment Contamination KW - Clones KW - carbon sources KW - Community composition KW - Community structure KW - Spatial heterogeneity KW - Microbiology KW - Microorganisms KW - Monitoring KW - Pollution monitoring KW - Carbon sources KW - DNA sequencing KW - Growth KW - Carbon KW - Gene libraries KW - Sampling KW - Heterogeneity KW - Plumes KW - Sediment pollution KW - Sediments KW - Light effects KW - DNA KW - rRNA 16S KW - D 04070:Pollution KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution KW - Q5 08502:Methods and instruments KW - A 01320:Microbial Degradation KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19978776?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=The+Microbial+Community+Structure+in+Petroleum-Contaminated+Sediments+Corresponds+to+Geophysical+Signatures&rft.au=Allen%2C+Jonathan+P%3BAtekwana%2C+Estella+A%3BAtekwana%2C+Eliot+A%3BDuris%2C+Joseph+W%3BWerkema%2C+DDale%3BRossbach%2C+Silvia&rft.aulast=Allen&rft.aufirst=Jonathan&rft.date=2007-05-01&rft.volume=73&rft.issue=9&rft.spage=2860&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Clones; Pollution monitoring; Sediment pollution; Community composition; Growth; Bioremediation; Petroleum; Microbiology; DNA; Sediments; Carbon sources; Light effects; DNA sequencing; Community structure; Gene libraries; Spatial heterogeneity; Sampling; rRNA 16S; Plumes; carbon sources; Carbon; Libraries; Microorganisms; Sediment Contamination; Monitoring; Heterogeneity ER - TY - JOUR T1 - Monochloramine Inactivation of Bacterial Select Agents AN - 19860743; 7414468 AB - Seven species of bacterial select agents were tested for susceptibility to monochloramine. Under test conditions, the monochloramine routinely maintained in potable water would reduce six of the species by 2 orders of magnitude within 4.2 h. Bacillus anthracis spores would require up to 3.5 days for the same inactivation with monochloramine. JF - Applied and Environmental Microbiology AU - Rose, Laura J AU - Rice, Eugene W AU - Hodges, Lisa AU - Peterson, Alicia AU - Arduino, Matthew J AD - Centers for Disease Control and Prevention, Atlanta, Georgia. U.S. Environmental Protection Agency, Cincinnati, Ohio Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 3437 EP - 3439 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 73 IS - 10 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Monochloramine KW - Bacillus anthracis KW - Drinking water KW - Spores KW - A 01490:Miscellaneous KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19860743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Monochloramine+Inactivation+of+Bacterial+Select+Agents&rft.au=Rose%2C+Laura+J%3BRice%2C+Eugene+W%3BHodges%2C+Lisa%3BPeterson%2C+Alicia%3BArduino%2C+Matthew+J&rft.aulast=Rose&rft.aufirst=Laura&rft.date=2007-05-01&rft.volume=73&rft.issue=10&rft.spage=3437&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Monochloramine; Spores; Drinking water; Bacillus anthracis ER - TY - JOUR T1 - Turbidity Tolerances of Great Lakes Coastal Wetland Fishes AN - 19713105; 7474272 AB - Despite recent interest in assessing the condition of fish assemblages in Great Lakes coastal wetlands and a concern for increasing turbidity as a major stressor pathway influencing these ecosystems, there is little information on fish tolerance or intolerance to turbidity on which to base wetland assessment metrics. Existing studies have borrowed tolerance designations from the stream literature, but they have not confirmed that the designations apply to Great Lakes wetlands or that designations based on tolerance to degradation in general apply to turbidity in particular. We used a published graphical method to determine turbidity tolerances of Great Lakes fishes based on their pattern of occurrence and relative abundance across coastal wetlands spanning a turbidity gradient. Fish composition data were obtained from fyke-net and electrofishing surveys of 75 wetlands along the U.S. shoreline of the Laurentian Great Lakes, representing a turbidity range of approximately 0-110 nephelometric turbidity units (NTU). Turbidity levels of 10, 25, and 50 NTU (corresponding to the thresholds in use for state water quality criteria) were used to separate fish into tolerance classes. We found that the turbidity tolerances of many species in Great Lakes wetlands differed from the published tolerances to general degradation in streams. Also, the tolerance levels for many species were unclear owing to the species infrequent occurrence. Although many of the wetlands sampled had quite low turbidity, a large proportion of the fish species were tolerant or moderately tolerant to turbidity and very few were intolerant, suggesting that enumerating intolerant species may not be a useful metric or that the metric should be expanded to include moderately intolerant species. Our study lays the foundation for additional turbidity indicator development efforts for Great Lakes coastal wetlands. JF - North American Journal of Fisheries Management AU - Trebitz, Anett S AU - Brazner, John C AU - Brady, Valerie J AU - Axler, Richard AU - Tanner, Danny K AD - U.S. Environmental Protection Agency, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804, USA, Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 619 EP - 633 PB - American Fisheries Society, 5410 Grosvenor Ln. Ste. 110 Bethesda MD 20814-2199 USA VL - 27 IS - 2 SN - 0275-5947, 0275-5947 KW - Aqualine Abstracts; Ecology Abstracts; Pollution Abstracts; Sustainability Science Abstracts; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Tolerance KW - Ecosystems KW - Abundance KW - Freshwater KW - Freshwater fish KW - Water quality KW - Lakes KW - foundations KW - Fishery management KW - Wetlands KW - Water Quality KW - water quality criteria KW - Fish KW - Fish Populations KW - Intolerance KW - Turbidity KW - Degradation KW - Streams KW - Pisces KW - Assessments KW - Coastal fisheries KW - Biological surveys KW - Stock assessment KW - relative abundance KW - fishery management KW - USA KW - North America, Great Lakes KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - Q1 08604:Stock assessment and management KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19713105?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=North+American+Journal+of+Fisheries+Management&rft.atitle=Turbidity+Tolerances+of+Great+Lakes+Coastal+Wetland+Fishes&rft.au=Trebitz%2C+Anett+S%3BBrazner%2C+John+C%3BBrady%2C+Valerie+J%3BAxler%2C+Richard%3BTanner%2C+Danny+K&rft.aulast=Trebitz&rft.aufirst=Anett&rft.date=2007-05-01&rft.volume=27&rft.issue=2&rft.spage=619&rft.isbn=&rft.btitle=&rft.title=North+American+Journal+of+Fisheries+Management&rft.issn=02755947&rft_id=info:doi/10.1577%2FM05-219.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Biological surveys; Fishery management; Abundance; Stock assessment; Coastal fisheries; Wetlands; Water quality; Freshwater fish; Turbidity; Streams; Intolerance; water quality criteria; foundations; Lakes; Ecosystems; Degradation; relative abundance; fishery management; Fish; Tolerance; Assessments; Water Quality; Fish Populations; Pisces; USA; North America, Great Lakes; Freshwater DO - http://dx.doi.org/10.1577/M05-219.1 ER - TY - JOUR T1 - Prochloraz Inhibits Testosterone Production at Dosages below Those that Affect Androgen-Dependent Organ Weights or the Onset of Puberty in the Male Sprague Dawley Rat AN - 19678707; 7421932 AB - Prochloraz (PCZ) is an imidazole fungicide that inhibits gonadal steroidogenesis and antagonizes the androgen receptor (AR). We hypothesized that pubertal exposure to PCZ would reduce testosterone production and delay male rat reproductive development. Sprague Dawley rats were dosed by gavage with 0, 31.3, 62.5, or 125 mg/kg/day of PCZ from postnatal day (PND) 23 to 42 or 51. There was a significant delay in preputial separation (PPS) at 125 mg/kg/day PCZ and several of the androgen-dependent organ weights were decreased significantly, but the significant organ weight effects were not consistent between the 2 necropsies (PND 42 vs. 51). At both ages, serum testosterone levels and ex vivo testosterone release from the testis were significantly decreased whereas serum progesterone and 17 alpha -hydroxyprogesterone levels were significantly increased at dose levels below those that affected PPS or reproductive organ weights. The hormone results suggested that PCZ was inhibiting CYP17 activity. In a second pubertal study (0, 3.9, 7.8, 15.6, 31.3, or 62.5 mg/kg/day PCZ), serum testosterone levels and ex vivo testosterone production were significantly reduced at 15.6 mg/kg/day PCZ. In order to examine the AR antagonism effects of PCZ, independent of its effects on testosterone synthesis, castrated immature male rats were dosed with androgen and 0, 15.6, 31.3, 62.5, or 125 mg/kg/day PCZ for 10-11 days (Hershberger assay). In this assay, androgen-sensitive organ weights were only significantly decreased at 125 mg/kg/day PCZ. These data from the pubertal assays demonstrate that PCZ decreases testosterone levels and delays rat pubertal development, as hypothesized. However, the fact that hormone levels were affected at dosage eightfold below that which delayed the onset of puberty suggests that rather large reductions in serum testosterone may be required to delay puberty and consistently reduce androgen-dependent tissue weights. JF - Toxicological Sciences AU - Blystone, Chad R AU - Furr, Johnathan AU - Lambright, Christy S AU - Howdeshell, Kembra L AU - Ryan, Bryce C AU - Wilson, Vickie S AU - LeBlanc, Gerald A AU - Gray, Leon Earl, Jr AD - Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina 27695. Reproductive Toxicology Division, Endocrinology Branch, National Human and Environmental Effects Research Laboratories, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711. Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina 27599 Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 65 EP - 74 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 97 IS - 1 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Testes KW - Autopsy KW - imidazole KW - Progesterone KW - Steroidogenesis KW - Hormones KW - Androgen receptors KW - Testosterone KW - Prochloraz KW - Fungicides KW - Reproductive organs KW - Androgens KW - Puberty KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19678707?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Prochloraz+Inhibits+Testosterone+Production+at+Dosages+below+Those+that+Affect+Androgen-Dependent+Organ+Weights+or+the+Onset+of+Puberty+in+the+Male+Sprague+Dawley+Rat&rft.au=Blystone%2C+Chad+R%3BFurr%2C+Johnathan%3BLambright%2C+Christy+S%3BHowdeshell%2C+Kembra+L%3BRyan%2C+Bryce+C%3BWilson%2C+Vickie+S%3BLeBlanc%2C+Gerald+A%3BGray%2C+Leon+Earl%2C+Jr&rft.aulast=Blystone&rft.aufirst=Chad&rft.date=2007-05-01&rft.volume=97&rft.issue=1&rft.spage=65&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Testes; Autopsy; imidazole; Progesterone; Hormones; Steroidogenesis; Androgen receptors; Testosterone; Prochloraz; Fungicides; Reproductive organs; Puberty; Androgens ER - TY - JOUR T1 - Bole water content shows little seasonal variation in century-old Douglas-fir trees AN - 19662246; 7423746 AB - Purportedly, large Douglas-fir trees in the American Pacific Northwest use water stored in bole tissues to ameliorate the effects of seasonal summer drought, the water content of bole tissues being drawn down over the summer months and replenished during the winter. Continuous monitoring of bole relative water content (RWC) in two 110-120-year-old Douglas-fir trees with ThetaProbe impedance devices provided an integrated measure of phloem-sapwood water content over 4 years. Seasonal changes in RWC closely tracked cambial activity and wood formation, but lagged changes in soil water content by 2-3 months. The RWC in the combined phloem and sapwood markedly increased during earlywood production in the late spring and early summer to maximum values of 64-77% as plant available soil water (ASW) decreased by similar to 60%. With transition and latewood formation, RWC decreased to minimum values of 59-72%, even as ASW increased in the fall. The difference between minimum RWC in the fall and maximum RWC in midsummer was only similar to 5%. Seasonal changes in bole RWC corresponded to cambial phenology, although decreasing AWS appeared to trigger the shift from earlywood to latewood formation. JF - Tree Physiology AU - Beedlow, P A AU - Tingey, D T AU - Waschmann, R S AU - Phillips, D L AU - Johnson, M G AD - U.S. Environmental Protection Agency, 200 SW 35th Street, Corvallis, OR 97333, USA, beedlow.peter@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 737 EP - 747 VL - 27 IS - 5 SN - 0829-318X, 0829-318X KW - Ecology Abstracts KW - Soil KW - Phenology KW - Trees KW - Phloem KW - Water content KW - Seasonal variations KW - Droughts KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19662246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tree+Physiology&rft.atitle=Bole+water+content+shows+little+seasonal+variation+in+century-old+Douglas-fir+trees&rft.au=Beedlow%2C+P+A%3BTingey%2C+D+T%3BWaschmann%2C+R+S%3BPhillips%2C+D+L%3BJohnson%2C+M+G&rft.aulast=Beedlow&rft.aufirst=P&rft.date=2007-05-01&rft.volume=40&rft.issue=14&rft.spage=4449&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Soil; Phenology; Trees; Phloem; Water content; Droughts; Seasonal variations ER - TY - JOUR T1 - Self-assembling Plants and Integration across Ecological Scales AN - 19658253; 7403910 AB - BACKGROUND AND AIMS: Although individual plants exhibit much complex behaviour in response to environmental stimuli, they appear to do so without any identifiable centres of organization. We review a special class of model with the aim of testing whether plants can effectively be self-assembling, modular-driven organisms, in the sense that whole-plant organization and behaviour emerges solely from the interactions of much smaller structural elements. We also review evidence that still higher-level behaviour, at the population and community levels of organization, can emerge from this same source. METHODS: In previous work we devised a special cellular automaton (CA) model of plant growth. This comprises a section depicting a two-dimensional plant in its above- and below-ground environments. The whole plant is represented by branching structures made up from identical 'modules'. The activity of these modules is driven by morphological, physiological and reproductive rulesets derived from comparative plant ecology, a feature which lends itself to experimentation at several ecological scales. KEY RESULTS: From real experiments using virtual plants we show that the model can reproduce a very wide range of whole-plant-, population- and community-level behaviour. All of these properties emerge successfully from a ruleset acting only at the level of the CA module. CONCLUSIONS: The CA model can, with advantage, be driven by C-S-R plant strategy theory. As this theory can ascribe a functional classification to any temperate angiosperm on the basis of a few simple tests, any community of such plants can be redescribed in terms of its 'functional signature' and the net environment that it experiences. To a valuable first approximation, therefore, a C-S-R version of the CA model can simulate the most essential properties both of natural vegetation and of its environment. We have thus achieved a position from which we can test a plethora of high-level community processes, such as diversity, vulnerability, resistance, resilience, stability, and habitat-community heterogeneity - processes which, if investigated on the scales truly required for a full understanding, would fall beyond the practical scope of even the largest real-life investigation. JF - Annals of Botany AU - Hunt, Roderick AU - Colasanti, R L AD - School of Biosciences, University of Exeter, The Innovation Centre, Rennes Drive, Exeter, EX4 4RN, UK. US Environmental Protection Agency, 200 SW 35th Street, Corvallis, OR 97333, USA. CSIRO, Long Pocket Laboratories, 120 Meiers Road, Indooroopilly, QLD 4068, Australia Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 1023 EP - 1034 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 99 IS - 5 SN - 0305-7364, 0305-7364 KW - Ecology Abstracts KW - Integration KW - Reviews KW - Plant communities KW - Environmental effects KW - Angiosperms KW - Natural vegetation KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19658253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Botany&rft.atitle=Self-assembling+Plants+and+Integration+across+Ecological+Scales&rft.au=Hunt%2C+Roderick%3BColasanti%2C+R+L&rft.aulast=Hunt&rft.aufirst=Roderick&rft.date=2007-05-01&rft.volume=99&rft.issue=5&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=Annals+of+Botany&rft.issn=03057364&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Integration; Reviews; Environmental effects; Plant communities; Angiosperms; Natural vegetation ER - TY - JOUR T1 - A compilation of in vitro rate and affinity values for xenobiotic biotransformation in fish, measured under physiological conditions AN - 19494163; 8579676 AB - Scientific literature from the past 25 years was searched to obtain in vitro biotransformation rate and affinity data for fish. To maximize the environmental relevance of this dataset, we focused on studies conducted at multiple substrate concentrations, and established acceptance criteria with respect to assay temperature and pH. Altogether, enzyme rate and affinity parameters are provided for 43 species and 77 compounds. In all but three instances, the reported reactions exhibited saturation at high substrate concentrations and could be used to calculate Michaelis-Menten rate (V sub(max)) and affinity (K sub(m)) constants. Most of this information was obtained using in vitro systems derived from liver tissue. Information from non-hepatic tissues was included, however, to provide a basis for comparisons among tissues. Where possible, in vitro enzyme parameters were examined to compare: (1) hepatic metabolism of a common substrate within a species, (2) hepatic metabolism of common substrates by different species, and (3) metabolism of a common substrate by different tissues of one species. Comparisons within species highlight a number of factors that may substantially influence xenobiotic metabolism in fish including gender, life stage, and acclimation temperature. Limited data suggest that V sub(max) and K sub(m) for the same reaction may vary by up to three orders of magnitude among species. JF - Comparative Biochemistry and Physiology, Part C: Toxicology & Pharmacology AU - Fitzsimmons, Patrick N AU - Lien, Gregory J AU - Nichols, John W AD - U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804, USA, fitzsimmons.patrick@epa.gov Y1 - 2007/05// PY - 2007 DA - May 2007 SP - 485 EP - 506 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 145 IS - 4 SN - 1532-0456, 1532-0456 KW - Pollution Abstracts; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Fish KW - Biotransformation KW - Enzymes KW - Affinity KW - Rate KW - Temperature effects KW - Biochemistry KW - Body conditions KW - Physiology KW - Temperature KW - Xenobiotics KW - Saturation KW - Environmental factors KW - Acclimation KW - Fish physiology KW - Gender KW - Substrates KW - Assay KW - Liver KW - Metabolism KW - pH KW - Sex KW - Q1 08346:Physiology, biochemistry, biophysics KW - SW 3030:Effects of pollution KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19494163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Comparative+Biochemistry+and+Physiology%2C+Part+C%3A+Toxicology+%26+Pharmacology&rft.atitle=A+compilation+of+in+vitro+rate+and+affinity+values+for+xenobiotic+biotransformation+in+fish%2C+measured+under+physiological+conditions&rft.au=Fitzsimmons%2C+Patrick+N%3BLien%2C+Gregory+J%3BNichols%2C+John+W&rft.aulast=Fitzsimmons&rft.aufirst=Patrick&rft.date=2007-05-01&rft.volume=145&rft.issue=4&rft.spage=485&rft.isbn=&rft.btitle=&rft.title=Comparative+Biochemistry+and+Physiology%2C+Part+C%3A+Toxicology+%26+Pharmacology&rft.issn=15320456&rft_id=info:doi/10.1016%2Fj.cbpc.2006.12.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Acclimation; Body conditions; Fish physiology; Environmental factors; Sex; Gender; Physiology; Liver; Temperature; Enzymes; Xenobiotics; pH; Metabolism; Biochemistry; Biotransformation; Assay; Substrates; Fish; Saturation DO - http://dx.doi.org/10.1016/j.cbpc.2006.12.011 ER - TY - JOUR T1 - Sustainability at the U.S. Environmental Protection Agency: 1970-2020 AN - 19454498; 7483644 AB - Perhaps reflecting the minor role that sustainability plays in EPA's statutory mission, the agency has adapted to changing environmental issues in an often slow and uneven manner to make sustainability a key element of its environmental policy. This article uses the words of past and present EPA administrators to identify major themes contributing to sustainability and assesses how a regulatory agency created to address pollution control has evolved to face new problems resulting from population increases, urbanization, and global economic growth. EPA can enhance its role in promoting sustainability by redefining relationships with the regulated community, defining and measuring sustainable outcomes, using science to support sustainable decision-making, and promoting stewardship and collaborative problem solving. Between now and 2020, as key environmental questions relate ever more closely to sustainability, EPA can draw upon the best of its experience, knowledge, and resources to play a central role in leading the public and private sectors towards sustainability. JF - Ecological Engineering AU - Grossarth, S K AU - Hecht, AD AD - Office of Research and Development, Mail Code 8101R, 1200 Pennsylvania Avenue NW, Washington, DC 20460, USA, hecht.alan@epa.gov Y1 - 2007/05/01/ PY - 2007 DA - 2007 May 01 SP - 1 EP - 8 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 30 IS - 1 SN - 0925-8574, 0925-8574 KW - Pollution Abstracts; Ecology Abstracts; Sustainability Science Abstracts KW - Urbanization KW - Sustainable development KW - economic growth KW - Population dynamics KW - Environmental policy KW - private sector KW - EPA KW - Decision making KW - USA KW - Economics KW - Problem solving KW - sustainability KW - Pollution control KW - D 04070:Pollution KW - P 9000:ENVIRONMENTAL ACTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19454498?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Engineering&rft.atitle=Sustainability+at+the+U.S.+Environmental+Protection+Agency%3A+1970-2020&rft.au=Grossarth%2C+S+K%3BHecht%2C+AD&rft.aulast=Grossarth&rft.aufirst=S&rft.date=2007-05-01&rft.volume=30&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Ecological+Engineering&rft.issn=09258574&rft_id=info:doi/10.1016%2Fj.ecoleng.2006.09.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Decision making; Urbanization; Economics; Problem solving; Environmental policy; Pollution control; EPA; Sustainable development; economic growth; sustainability; Population dynamics; private sector; USA DO - http://dx.doi.org/10.1016/j.ecoleng.2006.09.011 ER - TY - JOUR T1 - Relating fine root biomass to soil and climate conditions in the Pacific Northwest AN - 19666034; 7429940 AB - The additive contribution of fine root biomass for Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco var. menziesii) and western hemlock (Tsuga heterophylla (Raf.) Sarg.) to the stand average fine root biomass were estimated for eight conifer stands in the Pacific Northwest. Based on the Ribbens model fits to root coring data and the size and location of trees in the conifer stands, the estimated stand-level fine root biomass was 188-1157gm super(-) super(2) for P. menziesii and 24-347gm super(-) super(2) for T. heterophylla. Site differences in the stand-level fine root biomass for P. menziesii and T. heterophylla were largely explained by climate and soil nitrogen. Fine root biomass for P. menziesii was inversely related to soil nitrogen and, to a lesser extent, annual precipitation and temperature. These relationships were unchanged when data from our sites and four studies in the published literature were combined. In comparison, fine root biomass for T. heterophylla was positively related to temperature and precipitation and, to a lesser extent, inversely related to soil nitrogen. Because temperature and precipitation have opposite effects on fine root biomass for P. menziesii and T. heterophylla, these climate variables were not important predictor variables for total fine root biomass. In addition, the inverse relationship between total fine root biomass and soil nitrogen was obscured and confounded by the root-climate-species interaction. JF - Forest Ecology and Management AU - Lee, E H AU - Tingey, D T AU - Beedlow, P A AU - Johnson, M G AU - Burdick, CA AD - 200 SW 35th Street, Corvallis, OR 97333, United States, lee.ehenry@epa.gov Y1 - 2007/04/30/ PY - 2007 DA - 2007 Apr 30 SP - 195 EP - 208 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 242 IS - 2-3 SN - 0378-1127, 0378-1127 KW - Ecology Abstracts; Sustainability Science Abstracts KW - Soil KW - Conifers KW - Climate KW - Pseudotsuga menziesii KW - Roots KW - Precipitation KW - Tsuga heterophylla KW - Biomass KW - Nitrogen KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19666034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Forest+Ecology+and+Management&rft.atitle=Relating+fine+root+biomass+to+soil+and+climate+conditions+in+the+Pacific+Northwest&rft.au=Lee%2C+E+H%3BTingey%2C+D+T%3BBeedlow%2C+P+A%3BJohnson%2C+M+G%3BBurdick%2C+CA&rft.aulast=Lee&rft.aufirst=E&rft.date=2007-04-30&rft.volume=242&rft.issue=2-3&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Forest+Ecology+and+Management&rft.issn=03781127&rft_id=info:doi/10.1016%2Fj.foreco.2007.01.033 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Conifers; Soil; Climate; Roots; Precipitation; Biomass; Nitrogen; Pseudotsuga menziesii; Tsuga heterophylla DO - http://dx.doi.org/10.1016/j.foreco.2007.01.033 ER - TY - CPAPER T1 - A Landscape Development Intensity Index Map of Maryland, USA T2 - 2007 Meeting of the Association of American Geographers AN - 39398049; 4605978 JF - 2007 Meeting of the Association of American Geographers AU - White, Denis AU - Campbell, Daniel AU - Jackson, Laura Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - USA, Maryland KW - Landscape KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39398049?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Meeting+of+the+Association+of+American+Geographers&rft.atitle=A+Landscape+Development+Intensity+Index+Map+of+Maryland%2C+USA&rft.au=White%2C+Denis%3BCampbell%2C+Daniel%3BJackson%2C+Laura&rft.aulast=White&rft.aufirst=Denis&rft.date=2007-04-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Meeting+of+the+Association+of+American+Geographers&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Inland Sensitivity Atlas T2 - 2007 Meeting of the Association of American Geographers AN - 39371330; 4606028 JF - 2007 Meeting of the Association of American Geographers AU - Whelan, Ann Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - Atlases KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39371330?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Meeting+of+the+Association+of+American+Geographers&rft.atitle=Inland+Sensitivity+Atlas&rft.au=Whelan%2C+Ann&rft.aulast=Whelan&rft.aufirst=Ann&rft.date=2007-04-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Meeting+of+the+Association+of+American+Geographers&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of the Input-Output Framework to Assess Resource Scarcity T2 - 2007 Meeting of the Association of American Geographers AN - 39364531; 4604725 JF - 2007 Meeting of the Association of American Geographers AU - Gamas, Julia Andrea Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - Scarcity KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39364531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Meeting+of+the+Association+of+American+Geographers&rft.atitle=Evaluation+of+the+Input-Output+Framework+to+Assess+Resource+Scarcity&rft.au=Gamas%2C+Julia+Andrea&rft.aulast=Gamas&rft.aufirst=Julia&rft.date=2007-04-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Meeting+of+the+Association+of+American+Geographers&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - NEPAssist: A Web based Application for Environmental Assessment T2 - 2007 Meeting of the Association of American Geographers AN - 39362890; 4606026 JF - 2007 Meeting of the Association of American Geographers AU - Maso, Carmen Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - Environmental assessment KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39362890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Meeting+of+the+Association+of+American+Geographers&rft.atitle=NEPAssist%3A+A+Web+based+Application+for+Environmental+Assessment&rft.au=Maso%2C+Carmen&rft.aulast=Maso&rft.aufirst=Carmen&rft.date=2007-04-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Meeting+of+the+Association+of+American+Geographers&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A GIS Approach to Water Quality Stream Monitoring in American Samoa T2 - 2007 Meeting of the Association of American Geographers AN - 39361743; 4605578 JF - 2007 Meeting of the Association of American Geographers AU - Zennaro, Barbara AU - Buchan, Edna Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - Pacific, American Samoa KW - Water quality KW - Geographic information systems KW - Streams KW - Pollution monitoring KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39361743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Educational+Research&rft.atitle=The+Importance+of+Emotion+in+Theories+of+Motivation%3A+Empirical%2C+Methodological%2C+and+Theoretical+Considerations+from+a+Goal+Theory+Perspective&rft.au=Turner%2C+Julianne+C.%3BMeyer%2C+Debra+K.%3BSchweinle%2C+Amy&rft.aulast=Turner&rft.aufirst=Julianne&rft.date=2003-01-01&rft.volume=39&rft.issue=4&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Educational+Research&rft.issn=08830355&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cultivating this Green Frontier: Branding Ecosystem Service Credits T2 - 2007 Meeting of the Association of American Geographers AN - 39314988; 4605664 JF - 2007 Meeting of the Association of American Geographers AU - Robertson, Morgan M Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - Rental KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39314988?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Educational+Research&rft.atitle=The+Importance+of+Emotion+in+Theories+of+Motivation%3A+Empirical%2C+Methodological%2C+and+Theoretical+Considerations+from+a+Goal+Theory+Perspective&rft.au=Turner%2C+Julianne+C.%3BMeyer%2C+Debra+K.%3BSchweinle%2C+Amy&rft.aulast=Turner&rft.aufirst=Julianne&rft.date=2003-01-01&rft.volume=39&rft.issue=4&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Educational+Research&rft.issn=08830355&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Enterprise Architecture: Solutions for Our Future T2 - 2007 Meeting of the Association of American Geographers AN - 39310285; 4606029 JF - 2007 Meeting of the Association of American Geographers AU - Berish, Cory W Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - USA KW - EPA KW - Geographic information systems KW - Environmental protection KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39310285?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Meeting+of+the+Association+of+American+Geographers&rft.atitle=Enterprise+Architecture%3A+Solutions+for+Our+Future&rft.au=Berish%2C+Cory+W&rft.aulast=Berish&rft.aufirst=Cory&rft.date=2007-04-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Meeting+of+the+Association+of+American+Geographers&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Hierarchical Approach to High-Resolution, Hyperspectral Image Classification for Environmental Assessment T2 - 2007 Meeting of the Association of American Geographers AN - 39302954; 4606027 JF - 2007 Meeting of the Association of American Geographers AU - Troyer, Michael E AU - Heo, Joon AU - Pattnaik, Sitansu Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - Environmental assessment KW - Classification KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39302954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Meeting+of+the+Association+of+American+Geographers&rft.atitle=A+Hierarchical+Approach+to+High-Resolution%2C+Hyperspectral+Image+Classification+for+Environmental+Assessment&rft.au=Troyer%2C+Michael+E%3BHeo%2C+Joon%3BPattnaik%2C+Sitansu&rft.aulast=Troyer&rft.aufirst=Michael&rft.date=2007-04-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Meeting+of+the+Association+of+American+Geographers&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Rural Arizona Community Water Systems, Shortages and Vulnerability: Drought Impacts or Socially Constructed Water Scarcity? T2 - 2007 Meeting of the Association of American Geographers AN - 39301906; 4605566 JF - 2007 Meeting of the Association of American Geographers AU - Abraham, Joseph Scott Y1 - 2007/04/17/ PY - 2007 DA - 2007 Apr 17 KW - USA, Arizona KW - Droughts KW - Vulnerability KW - Scarcity KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39301906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Meeting+of+the+Association+of+American+Geographers&rft.atitle=Rural+Arizona+Community+Water+Systems%2C+Shortages+and+Vulnerability%3A+Drought+Impacts+or+Socially+Constructed+Water+Scarcity%3F&rft.au=Abraham%2C+Joseph+Scott&rft.aulast=Abraham&rft.aufirst=Joseph&rft.date=2007-04-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Meeting+of+the+Association+of+American+Geographers&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Venice under Siege by Biomass Burning T2 - 2007 General Assembly of the European Geosciences Union AN - 40596919; 4553546 JF - 2007 General Assembly of the European Geosciences Union AU - Latella, A AU - Marson, G AU - Benassi, A Y1 - 2007/04/15/ PY - 2007 DA - 2007 Apr 15 KW - Combustion products KW - Burning KW - Biomass KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40596919?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+General+Assembly+of+the+European+Geosciences+Union&rft.atitle=Venice+under+Siege+by+Biomass+Burning&rft.au=Latella%2C+A%3BMarson%2C+G%3BBenassi%2C+A&rft.aulast=Latella&rft.aufirst=A&rft.date=2007-04-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+General+Assembly+of+the+European+Geosciences+Union&rft.issn=&rft_id=info:doi/ L2 - http://www.cosis.net/members/meetings/programme/session_programme.php? m_id=40&p_id=233&day=0&view=session LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Intercomparison of the different Dispersion Schemes of the Atmospheric Pollutants in the Specific Conditions of an Impact Zone T2 - 2007 General Assembly of the European Geosciences Union AN - 40592877; 4553475 JF - 2007 General Assembly of the European Geosciences Union AU - Popescu, A AU - Stefan, S Y1 - 2007/04/15/ PY - 2007 DA - 2007 Apr 15 KW - Pollutants KW - Dispersion KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40592877?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+General+Assembly+of+the+European+Geosciences+Union&rft.atitle=Intercomparison+of+the+different+Dispersion+Schemes+of+the+Atmospheric+Pollutants+in+the+Specific+Conditions+of+an+Impact+Zone&rft.au=Popescu%2C+A%3BStefan%2C+S&rft.aulast=Popescu&rft.aufirst=A&rft.date=2007-04-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+General+Assembly+of+the+European+Geosciences+Union&rft.issn=&rft_id=info:doi/ L2 - http://www.cosis.net/members/meetings/programme/session_programme.php? m_id=40&p_id=233&day=0&view=session LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - A framework for risk assessment on soil erosion by water using an integrated and systematic approach AN - 20193574; 7458110 AB - A new approach for establishment of an analytical risk assessment model to evaluate the risk index for soil erosion by water is proposed, in which the remote sensing, GIS, the analytical hierarchy process (AHP), and modeling techniques are integrated through investigation of soil erosion by water in a joining area that partially covers the Shanxi province, Shaanxi province, and Inner Mongolia Autonomous Region of China. Based on field survey and information analyses, pertinent factors for soil erosion by water in this region are assessed and nine dominating factors are identified. The considered dominating factors include the soil type, rainstorm intensity, landform accounting for physiognomy type, ravine density, and land slope, vegetation coverage, mining area, level of water and soil conservation, and type of land uses. The GIS thematic layers of degrees of risk on soil erosion for those dominating factors are constructed. The weight of each thematic layer is determined through the AHP technique. This model is then applied in predicting development of soil erosion at a typical scenario for this study area. A brief discussion on construction and application of this model is presented. It is demonstrated that the presented methodology is practicable for establishing a risk assessment mode for soil erosion by water for an area of interest where pertinent information such as remote sensing data is available. A flowchart presenting a general procedure for implementation of the proposed approach is also included. JF - Journal of Hydrology (Amsterdam) AU - Wu, Q AU - Wang, M AD - U.S. EPA Robert S. Kerr Environmental Research Center, 919 Kerr Research Drive, Ada, OK 74820, USA, wang.mingyu@epa.gov Y1 - 2007/04/15/ PY - 2007 DA - 2007 Apr 15 SP - 11 EP - 21 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 337 IS - 1-2 SN - 0022-1694, 0022-1694 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Sustainability Science Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Remote Sensing KW - Risk assessment KW - Resource management KW - Landforms KW - Water conservation KW - Remote sensing KW - landforms KW - Soil erosion KW - China, People's Rep., Inner Mongolia KW - Risks KW - Hydrologic Models KW - Assessments KW - China, People's Rep., Shaanxi Prov. KW - Soils KW - Hydrology KW - Slopes KW - Geographical Information Systems KW - soil types KW - China, People's Rep., Shanxi Prov. KW - Vegetation KW - Land use KW - Risk KW - Soil Types KW - Soil conservation KW - China, People's Rep. KW - Geographic information systems KW - Mining KW - Soil Erosion KW - SW 5040:Data acquisition KW - Q2 09123:Conservation KW - M3 1010:Issues in Sustainable Development KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20193574?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hydrology+%28Amsterdam%29&rft.atitle=A+framework+for+risk+assessment+on+soil+erosion+by+water+using+an+integrated+and+systematic+approach&rft.au=Wu%2C+Q%3BWang%2C+M&rft.aulast=Wu&rft.aufirst=Q&rft.date=2007-04-15&rft.volume=337&rft.issue=1-2&rft.spage=11&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hydrology+%28Amsterdam%29&rft.issn=00221694&rft_id=info:doi/10.1016%2Fj.jhydrol.2007.01.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2016-04-29 N1 - SubjectsTermNotLitGenreText - Resource management; Landforms; Soils; Remote sensing; Hydrology; Soil conservation; Soil erosion; Land use; Risks; Risk assessment; soil types; Water conservation; Vegetation; landforms; Mining; Geographic information systems; Remote Sensing; Risk; Hydrologic Models; Assessments; Soil Types; Slopes; Soil Erosion; Geographical Information Systems; China, People's Rep., Shaanxi Prov.; China, People's Rep., Shanxi Prov.; China, People's Rep.; China, People's Rep., Inner Mongolia DO - http://dx.doi.org/10.1016/j.jhydrol.2007.01.022 ER - TY - CPAPER T1 - Oligonucleotide Microarray Analysis of Low-dose Ionizing Radiation Exposure T2 - 2007 Annual Meeting of the American Association for Cancer Research (AACR 2007) AN - 39339678; 4589874 JF - 2007 Annual Meeting of the American Association for Cancer Research (AACR 2007) AU - Silingardi, Paola AU - Morandi, Elena AU - Severini, Cinzia AU - Quercioli, Daniele AU - Vaccari, Monica AU - Horn, Wolfango AU - Nucci, Maria Concetta AU - Lodi, Vittorio AU - Violante, Francesco AU - Grilli, Sandro AU - Colacci, Annmaria Y1 - 2007/04/14/ PY - 2007 DA - 2007 Apr 14 KW - Ionizing radiation KW - Oligonucleotides KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39339678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Meeting+of+the+American+Association+for+Cancer+Research+%28AACR+2007%29&rft.atitle=Oligonucleotide+Microarray+Analysis+of+Low-dose+Ionizing+Radiation+Exposure&rft.au=Silingardi%2C+Paola%3BMorandi%2C+Elena%3BSeverini%2C+Cinzia%3BQuercioli%2C+Daniele%3BVaccari%2C+Monica%3BHorn%2C+Wolfango%3BNucci%2C+Maria+Concetta%3BLodi%2C+Vittorio%3BViolante%2C+Francesco%3BGrilli%2C+Sandro%3BColacci%2C+Annmaria&rft.aulast=Silingardi&rft.aufirst=Paola&rft.date=2007-04-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Meeting+of+the+American+Association+for+Cancer+Research+%28AACR+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey=%7BE3F401 9C%2D0A43%2D4514%2D8F66%2DB86DC90CD935%7D&AKey=%7B728BCE9C%2D121B%2D 46B9%2DA8EE%2DDC51FDFC6C15%7D LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dose-response Studies of Sodium Arsenite in the Skin of K6/ODC Transgenic Mouse T2 - 2007 Annual Meeting of the American Association for Cancer Research (AACR 2007) AN - 39311423; 4589814 JF - 2007 Annual Meeting of the American Association for Cancer Research (AACR 2007) AU - Ward, William O AU - Ahlborn, Gene J AU - Nelson, Gail M AU - Knapp, Geremy AU - Allen, James W AU - Roop, Barbara C AU - Kitchin, Kirk T AU - Delker, Don A AU - Ouyang, Ming AU - Chen, Yan AU - O'Brien, Thomas Y1 - 2007/04/14/ PY - 2007 DA - 2007 Apr 14 KW - Sodium KW - Dose-response effects KW - Skin KW - Sodium arsenite KW - Transgenic mice KW - Ornithine decarboxylase KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39311423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Meeting+of+the+American+Association+for+Cancer+Research+%28AACR+2007%29&rft.atitle=Dose-response+Studies+of+Sodium+Arsenite+in+the+Skin+of+K6%2FODC+Transgenic+Mouse&rft.au=Ward%2C+William+O%3BAhlborn%2C+Gene+J%3BNelson%2C+Gail+M%3BKnapp%2C+Geremy%3BAllen%2C+James+W%3BRoop%2C+Barbara+C%3BKitchin%2C+Kirk+T%3BDelker%2C+Don+A%3BOuyang%2C+Ming%3BChen%2C+Yan%3BO%27Brien%2C+Thomas&rft.aulast=Ward&rft.aufirst=William&rft.date=2007-04-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Meeting+of+the+American+Association+for+Cancer+Research+%28AACR+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey=%7BE3F401 9C%2D0A43%2D4514%2D8F66%2DB86DC90CD935%7D&AKey=%7B728BCE9C%2D121B%2D 46B9%2DA8EE%2DDC51FDFC6C15%7D LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative Microarray Expression Analysis of Selected Cancer-Relevant Genes in Hypertensive Resistant Versus Susceptible Rodent Stains T2 - 2007 Annual Meeting of the American Association for Cancer Research (AACR 2007) AN - 39311120; 4588661 JF - 2007 Annual Meeting of the American Association for Cancer Research (AACR 2007) AU - Heidenfelder, Brooke L AU - Reif, David M AU - Hubal, Elaine C AU - Bramble, Lori AU - Harkema, Jack R AU - Gallagher, Jane E Y1 - 2007/04/14/ PY - 2007 DA - 2007 Apr 14 KW - Rodents KW - Stains KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39311120?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Meeting+of+the+American+Association+for+Cancer+Research+%28AACR+2007%29&rft.atitle=Comparative+Microarray+Expression+Analysis+of+Selected+Cancer-Relevant+Genes+in+Hypertensive+Resistant+Versus+Susceptible+Rodent+Stains&rft.au=Heidenfelder%2C+Brooke+L%3BReif%2C+David+M%3BHubal%2C+Elaine+C%3BBramble%2C+Lori%3BHarkema%2C+Jack+R%3BGallagher%2C+Jane+E&rft.aulast=Heidenfelder&rft.aufirst=Brooke&rft.date=2007-04-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Meeting+of+the+American+Association+for+Cancer+Research+%28AACR+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey=%7BE3F401 9C%2D0A43%2D4514%2D8F66%2DB86DC90CD935%7D&AKey=%7B728BCE9C%2D121B%2D 46B9%2DA8EE%2DDC51FDFC6C15%7D LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Immune function is not impaired in Sprague-Dawley rats exposed to dimethyltin dichloride (DMTC) during development or adulthood AN - 20293229; 7483843 AB - Organotins are used commercially as pesticides, antifouling agents and stabilizers for polyvinyl chloride (PVC) pipe. Mono- and di-substituted butyltins, used in PVC pipe production, are of concern to the US EPA because they leach from supply pipes into drinking water and are reported multisystem toxicants. We assessed several immune functions in Sprague-Dawley rats after adult or developmental dimethyltin dichloride (DMTC) exposure because various organotins have been reported to be immunotoxic. Adult male and female rats were given drinking water containing 0, 20 or 40mg DMTC/L (0, 1.7, or 3.4mg DMTC/kg body weight [BW]) for 28 days. Pregnant females were given the same DMTC drinking water concentrations for a total of 37 days, from gestational day (GD) six through weaning of pups (0, 2.4, or 4.6mg DMTC/kg BW during gestational exposure; 0, 3.6, or 6.9mg DMTC/kg BW during postnatal exposure). On postnatal day (PND) two, litters were sexed, weighed, and culled to four males and four females per dam. Delayed-type hypersensitivity (DTH), antibody synthesis, and natural killer (NK) cell activity were evaluated in adults (N=8/sex/group) and in immunologically mature offspring (N=6/sex/group). Although water consumption was decreased in all of the DMTC dose groups, the immune functions evaluated were not affected. Our data suggest that these immune functions are not sensitive to the levels of DMTC anticipated to occur in drinking water delivered via PVC pipe as the concentrations we used were several orders of magnitude higher than those expected to leach from PVC pipes. JF - Toxicology AU - DeWitt, J C AU - Copeland, C B AU - Luebke, R W AD - University of North Carolina at Chapel Hill, c/o U.S. Environmental Protection Agency, MDB143-01, 109 TW Alexander Drive, Research Triangle Park, NC 27711, United States, jdewitt@email.unc.edu Y1 - 2007/04/11/ PY - 2007 DA - 2007 Apr 11 SP - 303 EP - 310 PB - Elsevier Science Ireland Ltd., P.O. Box 85 Limerick Ireland VL - 232 IS - 3 SN - 0300-483X, 0300-483X KW - Toxicology Abstracts; Immunology Abstracts KW - Organotin KW - Toxicants KW - polyvinyl chloride KW - Natural killer cells KW - Weaning KW - Development KW - Butyltin KW - Pregnancy KW - Antibodies KW - Hypersensitivity (delayed) KW - Body weight KW - Pesticides KW - Progeny KW - Immune response KW - Drinking water KW - F 06955:Immunomodulation & Immunopharmacology KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20293229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Immune+function+is+not+impaired+in+Sprague-Dawley+rats+exposed+to+dimethyltin+dichloride+%28DMTC%29+during+development+or+adulthood&rft.au=DeWitt%2C+J+C%3BCopeland%2C+C+B%3BLuebke%2C+R+W&rft.aulast=DeWitt&rft.aufirst=J&rft.date=2007-04-11&rft.volume=232&rft.issue=3&rft.spage=303&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2007.01.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Organotin; Toxicants; Natural killer cells; polyvinyl chloride; Weaning; Development; Pregnancy; Butyltin; Antibodies; Body weight; Hypersensitivity (delayed); Pesticides; Progeny; Immune response; Drinking water DO - http://dx.doi.org/10.1016/j.tox.2007.01.017 ER - TY - JOUR T1 - Framework analysis for the carcinogenic mode of action of nitrobenzene. AN - 70613524; 17558784 AB - Nitrobenzene (CASRN: 98-95-3) has been shown to induce cancers in many tissues including kidney, liver, and thyroid, following chronic inhalation in animals. However, with a few exceptions, genotoxicity assays using nitrobenzene have given negative results. Some DNA binding/adduct studies have brought forth questionable results and, considering the available weight of evidence, it does not appear that nitrobenzene causes cancer via a genotoxic mode of action. Nitrobenzene produces a number of free radicals during its reductive metabolism, in the gut as well as at the cellular level, and generates superoxide anion as a by-product during oxidative melabolism. The reactive species generated during nitrobenzene metabolism are considered candidates for carcinogenicity. Furthermore, several lines of evidence suggest that nitrobenzene exerts its carcinogenicity through a non-DNA reactive (epigenetic) fashion, such as a strong temporal relationship between non-, pre-, and neoplastic lesions leading to carcinogenesis. In this report, we first describe the absorption, distribution, metabolism, and excretion of nitrobenzene followed by a summary of the available genotoxicity studies and the only available cancer bioassay. We subsequently refer to the mode of action framework of the U.S. Environmental Protection Agency's 2005 Guidelines for Carcinogen Risk Assessment as a basis for presenting possible modes of action for nitrobenzene-induced cancers of the liver, thyroid, and kidney, as supported by the available experimental data. The rationale(s) regarding human relevance of each mode of action is also presented. Finally, we hypothesize that the carcinogenic mode of action for nitrobenzene is multifactorial in nature and reflective of free radicals, inflammation, and/or altered methylation. JF - Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews AU - Hsu, Ching-Hung AU - Stedeford, Todd AU - Okochi-Takada, Eriko AU - Ushijima, Toshikazu AU - Noguchi, Hitoshi AU - Muro-Cacho, Carlos AU - Holder, James W AU - Banasik, Marek AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency. Washington, DC, USA. chinghunghsu@yahoo.com PY - 2007 SP - 155 EP - 184 VL - 25 IS - 2 SN - 1059-0501, 1059-0501 KW - Carcinogens, Environmental KW - 0 KW - Mutagens KW - Nitrobenzenes KW - nitrobenzene KW - E57JCN6SSY KW - Index Medicus KW - Molecular Structure KW - Animals KW - Humans KW - Structure-Activity Relationship KW - Nitrobenzenes -- chemistry KW - Neoplasms -- chemically induced KW - Nitrobenzenes -- pharmacokinetics KW - Mutagens -- toxicity KW - Nitrobenzenes -- toxicity KW - Mutagens -- pharmacokinetics KW - Carcinogens, Environmental -- toxicity KW - Neoplasms -- genetics KW - Mutagens -- chemistry KW - Carcinogens, Environmental -- pharmacokinetics KW - Carcinogens, Environmental -- chemistry KW - Neoplasms -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70613524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.atitle=Framework+analysis+for+the+carcinogenic+mode+of+action+of+nitrobenzene.&rft.au=Hsu%2C+Ching-Hung%3BStedeford%2C+Todd%3BOkochi-Takada%2C+Eriko%3BUshijima%2C+Toshikazu%3BNoguchi%2C+Hitoshi%3BMuro-Cacho%2C+Carlos%3BHolder%2C+James+W%3BBanasik%2C+Marek&rft.aulast=Hsu&rft.aufirst=Ching-Hung&rft.date=2007-04-01&rft.volume=25&rft.issue=2&rft.spage=155&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.issn=10590501&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-18 N1 - Date created - 2007-06-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The MARE research program 1999-2006: reflections on program management. AN - 70525070; 17520922 JF - Ambio AU - Johansson, Sif AU - Wulff, Fredrik AU - Bonsdorff, Erik AD - Swedish Environmental Protection Agency, Stockholm, Sweden. sif.johansson@naturvardsverket.se Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 119 EP - 122 VL - 36 IS - 2-3 SN - 0044-7447, 0044-7447 KW - Water Pollutants KW - 0 KW - Index Medicus KW - Ecosystem KW - Program Development KW - Program Evaluation KW - Baltic States KW - Water Pollutants -- toxicity KW - Environmental Monitoring KW - Water Pollution -- economics KW - Safety Management -- methods KW - Marine Biology KW - Water Pollution -- prevention & control KW - Safety Management -- economics KW - Research KW - Eutrophication -- drug effects KW - Safety Management -- organization & administration KW - Eutrophication -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70525070?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ambio&rft.atitle=The+MARE+research+program+1999-2006%3A+reflections+on+program+management.&rft.au=Johansson%2C+Sif%3BWulff%2C+Fredrik%3BBonsdorff%2C+Erik&rft.aulast=Johansson&rft.aufirst=Sif&rft.date=2007-04-01&rft.volume=36&rft.issue=2-3&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=Ambio&rft.issn=00447447&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-31 N1 - Date created - 2007-05-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A meta-analysis of children's hand-to-mouth frequency data for estimating nondietary ingestion exposure. AN - 70508237; 17511707 AB - Because of their mouthing behaviors, children have a higher potential for exposure to available chemicals through the nondietary ingestion route; thus, frequency of hand-to-mouth activity is an important variable for exposure assessments. Such data are limited and difficult to collect. Few published studies report such information, and the studies that have been conducted used different data collection approaches (e.g., videography versus real-time observation), data analysis and reporting methods, ages of children, locations, and even definitions of "mouthing." For this article, hand-to-mouth frequency data were gathered from 9 available studies representing 429 subjects and more than 2,000 hours of behavior observation. A meta-analysis was conducted to study differences in hand-to-mouth frequency based on study, age group, gender, and location (indoor vs. outdoor), to fit variability and uncertainty distributions that can be used in probabilistic exposure assessments, and to identify any data gaps. Results of this analysis indicate that age and location are important for hand-to-mouth frequency, but study and gender are not. As age increases, both indoor and outdoor hand-to-mouth frequencies decrease. Hand-to-mouth behavior is significantly greater indoors than outdoors. For both indoor and outdoor hand-to-mouth frequencies, interpersonal, and intra-personal variability are approximately 60% and approximately 30%, respectively. The variance difference among different studies is much bigger than its mean, indicating that different studies with different methodologies have similar central values. Weibull distributions best fit the observed data for the different variables considered and are presented in this article by study, age group, and location. Average indoor hand-to-mouth behavior ranged from 6.7 to 28.0 contacts/hour, with the lowest value corresponding to the 6 to <11 year olds and the highest value corresponding to the 3 to <6 month olds. Average outdoor hand-to-mouth frequency ranged from 2.9 to 14.5 contacts/hour, with the lowest value corresponding to the 6 to <11 year olds and the highest value corresponding to the 6 to <12 month olds. The analysis highlights the need for additional hand-to-mouth data for the <3 months, 3 to <6 months, and 3 to <6 year age groups using standardized collection and analysis because of lack of data or high uncertainty in available data. This is the first publication to report Weibull distributions as the best fitting distribution for hand-to-mouth frequency; using the best fitting exposure factor distribution will help improve estimates of exposure. The analyses also represent a first comprehensive effort to fit hand-to-mouth frequency variability and uncertainty distributions by indoor/outdoor location and by age groups, using the new standard set of age groups recommended by the U.S. Environmental Protection Agency for assessing childhood exposures. Thus, the data presented in this article can be used to update the U.S. EPA's Child-Specific Exposure Factors Handbook and to improve estimates of nondietary ingestion in probabilistic exposure modeling. JF - Risk analysis : an official publication of the Society for Risk Analysis AU - Xue, Jianping AU - Zartarian, Valerie AU - Moya, Jacqueline AU - Freeman, Natalie AU - Beamer, Paloma AU - Black, Kathy AU - Tulve, Nicolle AU - Shalat, Stuart AD - U.S. Environmental Protection Agency, Boston, MA, USA. Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 411 EP - 420 VL - 27 IS - 2 SN - 0272-4332, 0272-4332 KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - Infant KW - Environmental Monitoring KW - Eating KW - Age Factors KW - Sex Factors KW - Humans KW - Child KW - Play and Playthings KW - Face KW - Risk Assessment KW - Child, Preschool KW - Environmental Pollutants -- toxicity KW - Motor Activity KW - Environmental Exposure KW - Mouth UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70508237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.atitle=A+meta-analysis+of+children%27s+hand-to-mouth+frequency+data+for+estimating+nondietary+ingestion+exposure.&rft.au=Xue%2C+Jianping%3BZartarian%2C+Valerie%3BMoya%2C+Jacqueline%3BFreeman%2C+Natalie%3BBeamer%2C+Paloma%3BBlack%2C+Kathy%3BTulve%2C+Nicolle%3BShalat%2C+Stuart&rft.aulast=Xue&rft.aufirst=Jianping&rft.date=2007-04-01&rft.volume=27&rft.issue=2&rft.spage=411&rft.isbn=&rft.btitle=&rft.title=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.issn=02724332&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-18 N1 - Date created - 2007-05-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Case study of contaminated groundwater discharge: how in situ tools link an evolving conceptual site model with management decisions. AN - 70466048; 17477296 AB - In this paper, we show how simple in situ tools provide key insights into groundwater transport and exposure pathways. We illustrate how integration between managers, hydrogeologists, and ecologists, through the use of an evolving conceptual site model, helps direct management decisions. An initial conceptual site model was used to guide a preliminary investigation to determine the extent to which contaminant exposure from discharging groundwater occurs in a waterway. Regulatory agency managers, informed by phased input of data, supported extending the site investigation subtidally to identify the nature and extent of waterway contamination and to provide the basis for developing remedial alternatives. Approaches and tools used in this reconnaissance investigation included monitoring ambient surface water for groundwater signatures, installing minipiezometers within the sediment, and installing diffusion samplers and seepage meters. Despite high concentrations of contaminants in nearby piezometer samples, the diffusion sampler array indicated few locations with contaminant accumulation in the top 20 cm of the sediment. At the location where deployed, seepage meters demonstrated a high degree of connectivity and the potential for mass loading in the waterway. In the collective experience of the authors, this is one of the 1st sites where this comprehensive suite of tools has been applied in a regulatory setting to evaluate the movement of industrial contaminants beneath and into a waterway. This approach was effective because of integration of disciplines, unification of previously separate groundwater and sediment investigations, and collaboration across separate agencies and programs. In large part because of the results, the facility and agency managers agreed, and have begun a comprehensive subtidal investigation, to characterize the distribution of sediment and groundwater contamination and to quantify the groundwater flux to the surface water. JF - Integrated environmental assessment and management AU - Duncan, P Bruce AU - Greenberg, Marc S AU - Leja, Stan AU - Williams, Jonathan AU - Black, Curt AU - Henry, Richard G AU - Wilhelm, Leon AD - US Environmental Protection Agency, Region 10, 1200-6th Avenue, Seattle, Washington 98101, USA. duncan.bruce@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 279 EP - 289 VL - 3 IS - 2 SN - 1551-3777, 1551-3777 KW - Water Pollutants KW - 0 KW - Index Medicus KW - Risk Management -- methods KW - Environmental Health KW - Water Movements KW - Diffusion KW - Geography KW - Decision Making KW - Models, Biological KW - Risk Assessment KW - Water Pollutants -- toxicity KW - Ecology KW - Water Pollutants -- analysis KW - Geologic Sediments -- analysis KW - Water Supply KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70466048?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Integrated+environmental+assessment+and+management&rft.atitle=Case+study+of+contaminated+groundwater+discharge%3A+how+in+situ+tools+link+an+evolving+conceptual+site+model+with+management+decisions.&rft.au=Duncan%2C+P+Bruce%3BGreenberg%2C+Marc+S%3BLeja%2C+Stan%3BWilliams%2C+Jonathan%3BBlack%2C+Curt%3BHenry%2C+Richard+G%3BWilhelm%2C+Leon&rft.aulast=Duncan&rft.aufirst=P&rft.date=2007-04-01&rft.volume=3&rft.issue=2&rft.spage=279&rft.isbn=&rft.btitle=&rft.title=Integrated+environmental+assessment+and+management&rft.issn=15513777&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-13 N1 - Date created - 2007-05-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. AN - 70451228; 17342777 AB - While an evaluation of the estrous cycle in laboratory rodents can be a useful measure of the integrity of the hypothalamic-pituitary-ovarian reproductive axis, it can also serve as a way of insuring that animals exhibiting abnormal cycling patterns are disincluded from a study prior to exposure to a test compound. Assessment of vaginal cytology in regularly cycling animals also provides a means to establish a comparable endocrine milieu for animals at necropsy. The procedure for obtaining a vaginal smear is relatively non-invasive and is one to which animals can become readily accustomed. It requires few supplies, and with some experience the assessments can be easily performed in fresh, unstained smears, or in fixed, stained ones. When incorporated as an adjunct to other endpoint measures, a determination of a female's cycling status can contribute important information about the nature of a toxicant insult to the reproductive system. In doing so, it can help to integrate the data into a more comprehensive mechanistic portrait of the effect, and in terms of risk assessment, may provide some indication of a toxicant's impact on human reproductive physiology. JF - Birth defects research. Part B, Developmental and reproductive toxicology AU - Goldman, Jerome M AU - Murr, Ashley S AU - Cooper, Ralph L AD - Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. goldman.jerome@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 84 EP - 97 VL - 80 IS - 2 SN - 1542-9733, 1542-9733 KW - Keratins KW - 68238-35-7 KW - Index Medicus KW - Keratins -- metabolism KW - Animals KW - Hypothalamo-Hypophyseal System -- drug effects KW - Euthanasia, Animal -- methods KW - Humans KW - Ovary -- drug effects KW - Models, Biological KW - Vaginal Smears -- methods KW - Risk Assessment KW - Hypothalamo-Hypophyseal System -- physiology KW - Sexual Behavior, Animal -- drug effects KW - Toxicity Tests -- methods KW - Ovary -- physiology KW - Female KW - Vagina -- drug effects KW - Rodentia -- physiology KW - Vagina -- cytology KW - Toxicology -- methods KW - Estrous Cycle -- physiology KW - Vagina -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70451228?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+B%2C+Developmental+and+reproductive+toxicology&rft.atitle=The+rodent+estrous+cycle%3A+characterization+of+vaginal+cytology+and+its+utility+in+toxicological+studies.&rft.au=Goldman%2C+Jerome+M%3BMurr%2C+Ashley+S%3BCooper%2C+Ralph+L&rft.aulast=Goldman&rft.aufirst=Jerome&rft.date=2007-04-01&rft.volume=80&rft.issue=2&rft.spage=84&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+B%2C+Developmental+and+reproductive+toxicology&rft.issn=15429733&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-06 N1 - Date created - 2007-05-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Atrazine and reproductive function: mode and mechanism of action studies. AN - 70442861; 17443714 AB - Atrazine, a chlorotriazine herbicide, is used to control annual grasses and broadleaf weeds. In this review, we summarize our laboratory's work evaluating the neuroendocrine toxicity of atrazine (and related chlorotriazines) from an historic perspective. We provide the rationale for our work as we have endeavored to determine: 1) the underlying reproductive changes leading to the development of mammary gland tumors in the atrazine-exposed female rat; 2) the cascade of physiological events that are responsible for these changes (i.e., the mode of action for mammary tumors); 3) the potential cellular mechanisms involving adverse effects of atrazine; and 4) the range of reproductive alterations associated with this pesticide. JF - Birth defects research. Part B, Developmental and reproductive toxicology AU - Cooper, Ralph L AU - Laws, Susan C AU - Das, Parikshit C AU - Narotsky, Michael G AU - Goldman, Jerome M AU - Lee Tyrey, E AU - Stoker, Tammy E AD - Endocrinology Branch, Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, United States Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. cooper.ralph@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 98 EP - 112 VL - 80 IS - 2 SN - 1542-9733, 1542-9733 KW - Chlorine Compounds KW - 0 KW - Estrogens KW - Herbicides KW - Prolactin KW - 9002-62-4 KW - Luteinizing Hormone KW - 9002-67-9 KW - Atrazine KW - QJA9M5H4IM KW - Index Medicus KW - Animals, Suckling KW - Animals KW - Hypothalamus -- physiology KW - Pituitary Gland -- physiology KW - Hypothalamus -- drug effects KW - Pregnancy, Animal -- drug effects KW - Mammary Neoplasms, Animal -- chemically induced KW - Pregnancy KW - Pituitary Gland -- drug effects KW - Sexual Maturation -- drug effects KW - Rats KW - Ovulation -- drug effects KW - Aging -- physiology KW - Chlorine Compounds -- toxicity KW - Ovulation -- blood KW - Prolactin -- secretion KW - Pregnancy Maintenance -- drug effects KW - Luteinizing Hormone -- blood KW - Herbicides -- toxicity KW - Estrogens -- physiology KW - Female KW - Reproduction -- drug effects KW - Atrazine -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70442861?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+B%2C+Developmental+and+reproductive+toxicology&rft.atitle=Atrazine+and+reproductive+function%3A+mode+and+mechanism+of+action+studies.&rft.au=Cooper%2C+Ralph+L%3BLaws%2C+Susan+C%3BDas%2C+Parikshit+C%3BNarotsky%2C+Michael+G%3BGoldman%2C+Jerome+M%3BLee+Tyrey%2C+E%3BStoker%2C+Tammy+E&rft.aulast=Cooper&rft.aufirst=Ralph&rft.date=2007-04-01&rft.volume=80&rft.issue=2&rft.spage=98&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+B%2C+Developmental+and+reproductive+toxicology&rft.issn=15429733&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-06 N1 - Date created - 2007-05-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Sensitivity analysis and evaluation of MicroFacPM: a microscale motor vehicle emission factor model for particulate matter emissions. AN - 70427024; 17458461 AB - A microscale emission factor model (MicroFacPM) for predicting real-time site-specific motor vehicle particulate matter emissions was presented in the companion paper titled "Development of a Microscale Emission Factor Model for Particulate Matter (MicroFacPM) for Predicting Real-Time Motor Vehicle Emissions". The emission rates discussed are in mass per unit distance with the model providing estimates of fine particulate matter (PM2.5) and coarse particulate matter. This paper complements the companion paper by presenting a sensitivity analysis of the model to input variables and evaluation model outputs using data from limited field studies. The sensitivity analysis has shown that MicroFacPM emission estimates are very sensitive to vehicle fleet composition, speed, and the percentage of high-emitting vehicles. The vehicle fleet composition can affect fleet emission rates from 8 mg/mi to 1215 mg/mi; an increase of 5% in the smoking (high-emitting) current average U.S. light-duty vehicle fleet (compared with 0%) increased PM2.5 emission rates by -272% for 2000; and for the current U.S. fleet, PM2.5 emission rates are reduced by a factor of -0.64 for speeds >50 miles per hour (mph) relative to a speed of 10 mph. MicroFacPM can also be applied to examine the contribution of emission rates per vehicle class, model year, and sources of PM. The model evaluation is presented for the Tuscarora Mountain Tunnel, Pennsylvania Turnpike, PA, and some limited evaluations at two locations: Sepulveda Tunnel, Los Angeles, CA, and Van Nuys Tunnel, Van Nuys, CA. In general, the performance of MicroFacPM has shown very encouraging results. JF - Journal of the Air & Waste Management Association (1995) AU - Singh, Rakesh B AU - Huber, Alan H AU - Braddock, James N AD - National Research Council Research Associate, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 420 EP - 433 VL - 57 IS - 4 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Particulate Matter KW - Vehicle Emissions KW - Index Medicus KW - United States KW - Sensitivity and Specificity KW - Motor Vehicles -- classification KW - Particle Size KW - Humans KW - Temperature KW - Observer Variation KW - Environmental Monitoring KW - Air Pollutants -- analysis KW - Particulate Matter -- analysis KW - Vehicle Emissions -- analysis KW - Models, Theoretical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70427024?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Sensitivity+analysis+and+evaluation+of+MicroFacPM%3A+a+microscale+motor+vehicle+emission+factor+model+for+particulate+matter+emissions.&rft.au=Singh%2C+Rakesh+B%3BHuber%2C+Alan+H%3BBraddock%2C+James+N&rft.aulast=Singh&rft.aufirst=Rakesh&rft.date=2007-04-01&rft.volume=57&rft.issue=4&rft.spage=420&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-25 N1 - Date created - 2007-04-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Dose-response relationship of prenatal mercury exposure and IQ: an integrative analysis of epidemiologic data. AN - 70411526; 17450232 AB - Prenatal exposure to mercury has been associated with adverse childhood neurologic outcomes in epidemiologic studies. Dose-response information for this relationship is useful for estimating benefits of reduced mercury exposure. We estimated a dose-response relationship between maternal mercury body burden and subsequent childhood decrements in intelligence quotient (IQ), using a Bayesian hierarchical model to integrate data from three epidemiologic studies. Inputs to the model consist of dose-response coefficients from studies conducted in the Faroe Islands, New Zealand, and the Seychelles Islands. IQ coefficients were available from previous work for the latter two studies, and a coefficient for the Faroe Islands study was estimated from three IQ subtests. Other tests of cognition/achievement were included in the hierarchical model to obtain more accurate estimates of study-to-study and end point-to-end point variability. We find a central estimate of -0.18 IQ points (95% confidence interval, -0.378 to -0.009) for each parts per million increase of maternal hair mercury, similar to the estimates for both the Faroe Islands and Seychelles studies, and lower in magnitude than the estimate for the New Zealand study. Sensitivity analyses produce similar results, with the IQ coefficient central estimate ranging from -0.13 to -0.25. IQ is a useful end point for estimating neurodevelopmental effects, but may not fully represent cognitive deficits associated with mercury exposure, and does not represent deficits related to attention and motor skills. Nevertheless, the integrated IQ coefficient provides a more robust description of the dose-response relationship for prenatal mercury exposure and cognitive functioning than results of any single study. JF - Environmental health perspectives AU - Axelrad, Daniel A AU - Bellinger, David C AU - Ryan, Louise M AU - Woodruff, Tracey J AD - Office of Policy, Economics, and Innovation, U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue NW, Washington, DC 20460, USA. axelrad.daniel@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 609 EP - 615 VL - 115 IS - 4 SN - 0091-6765, 0091-6765 KW - Environmental Pollutants KW - 0 KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - Endpoint Determination KW - Cognition Disorders -- epidemiology KW - Dose-Response Relationship, Drug KW - Body Burden KW - Humans KW - Seychelles -- epidemiology KW - Bayes Theorem KW - Child Development -- drug effects KW - Motor Skills Disorders -- chemically induced KW - Child KW - Cognition Disorders -- chemically induced KW - Pregnancy KW - Epidemiologic Studies KW - Adult KW - New Zealand -- epidemiology KW - Female KW - Intelligence KW - Mercury -- adverse effects KW - Mercury -- analysis KW - Environmental Pollutants -- analysis KW - Environmental Pollutants -- adverse effects KW - Prenatal Exposure Delayed Effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70411526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Dose-response+relationship+of+prenatal+mercury+exposure+and+IQ%3A+an+integrative+analysis+of+epidemiologic+data.&rft.au=Axelrad%2C+Daniel+A%3BBellinger%2C+David+C%3BRyan%2C+Louise+M%3BWoodruff%2C+Tracey+J&rft.aulast=Axelrad&rft.aufirst=Daniel&rft.date=2007-04-01&rft.volume=115&rft.issue=4&rft.spage=609&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-22 N1 - Date created - 2007-04-23 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Toxicol Lett. 2000 Mar 15;112-113:193-9 [10720731] Stat Med. 2008 Feb 28;27(5):698-710 [18069727] Environ Health Perspect. 2003 Aug;111(10):1318-25 [12896853] Environ Health Perspect. 2003 Sep;111(12):1465-70 [12948885] Environ Res. 2004 Jul;95(3):385-93 [15220072] Cancer Res. 1976 Sep;36(9 pt.1):2973-9 [975067] Neurotoxicol Teratol. 1997 Nov-Dec;19(6):417-28 [9392777] JAMA. 1998 Aug 26;280(8):701-7 [9728641] Risk Anal. 1998 Dec;18(6):701-13 [9972579] Am J Epidemiol. 1999 Aug 1;150(3):301-5 [10430235] MMWR Morb Mortal Wkly Rep. 2004 Nov 5;53(43):1018-20 [15525900] Environ Health. 2002 Oct 14;1(1):2 [12513702] Risk Anal. 2004 Dec;24(6):1689-96 [15660622] Environ Health Perspect. 2005 May;113(5):590-6 [15866768] Risk Anal. 2005 Apr;25(2):285-9 [15876204] Environ Health Perspect. 2005 Jul;113(7):894-9 [16002379] Neurotoxicology. 2006 Mar;27(2):147-52 [16159667] Lancet. 2003 May 17;361(9370):1686-92 [12767734] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of proposed physical ballast tank treatments on aquatic invertebrate resting eggs. AN - 70406652; 17447556 AB - Adaptations in aquatic invertebrate resting eggs that confer protection from natural catastrophic events also could confer protection from treatments applied to ballast water for biological invasion vector management. To evaluate the potential efficacy of physical ballast water treatment methods, the present study examined the acute toxicity of heat (flash and holding methods), ultraviolet (UV) radiation (254 nm), and deoxygenation (acute and chronic) on resting eggs of the freshwater cladoceran Daphnia mendotae and the marine brine shrimp Artemia sp. Both D. mendotae and Artemia sp. were similarly sensitive to flash exposures of heat (100% mortality at 70 degrees C), but D. mendotae were much more sensitive to prolonged exposures. Exposure to 4,000 mJ/cm2 of UV radiation resulted in mortality rates of 59% in Artemia sp. and 91% in D. mendotae. Deoxygenation to an oxygen concentration of 1 mg/L was maximally toxic to both species. Deoxygenation suppressed hatching of D. mendotae resting eggs at oxygen concentrations of less than 5.5 mg/L and of Artemia sp. resting eggs at concentrations of less than 1 mg/L. Results suggest that UV radiation and deoxygenation are not viable treatment methods with respect to invertebrate resting eggs because of the impracticality of producing sufficient UV doses and the suppression of hatching at low oxygen concentrations. Results also suggest that the treatment temperatures required to kill resting eggs are much higher than those reported to be effective against other invertebrate life stages and species. The results, however, do not preclude the effectiveness of these treatments against other organisms or life stages. Nevertheless, if ballast tank treatment systems employing the tested methods are intended to include mitigation of viable resting eggs, then physical removal of large resting eggs and ephippia via filtration would be a necessary initial step. JF - Environmental toxicology and chemistry AU - Raikow, David F AU - Reid, David F AU - Blatchley, Ernest R AU - Jacobs, Gregory AU - Landrum, Peter F AD - National Oceanic and Atmospheric Administration (NOAA), National Center for Research on Aquatic Invasive Species, 2205 Commonwealth Boulevard, Ann Arbor, Michigan 48105, USA. raikow.david@epamail.epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 717 EP - 725 VL - 26 IS - 4 SN - 0730-7268, 0730-7268 KW - Water KW - 059QF0KO0R KW - Oxygen KW - S88TT14065 KW - Index Medicus KW - Hot Temperature KW - Animals KW - Ultraviolet Rays KW - Oxygen -- analysis KW - Time Factors KW - Ships KW - Ovum -- radiation effects KW - Artemia KW - Water -- chemistry KW - Daphnia KW - Ovum -- drug effects KW - Water -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70406652?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Effects+of+proposed+physical+ballast+tank+treatments+on+aquatic+invertebrate+resting+eggs.&rft.au=Raikow%2C+David+F%3BReid%2C+David+F%3BBlatchley%2C+Ernest+R%3BJacobs%2C+Gregory%3BLandrum%2C+Peter+F&rft.aulast=Raikow&rft.aufirst=David&rft.date=2007-04-01&rft.volume=26&rft.issue=4&rft.spage=717&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-27 N1 - Date created - 2007-04-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Up-regulation of tissue factor in human pulmonary artery endothelial cells after ultrafine particle exposure. AN - 70404687; 17450221 AB - Epidemiology studies have linked exposure to pollutant particles to increased cardiovascular mortality and morbidity, but the mechanisms remain unknown. We tested the hypothesis that the ultrafine fraction of ambient pollutant particles would cause endothelial cell dysfunction. We profiled gene expression of human pulmonary artery endothelial cells (HPAEC) exposed to ultrafine particles (UFPs; 100 microg/mL) from Chapel Hill, North Carolina, or vehicle for 4 hr with Affymetrix HG U133 Plus 2.0 chips (n = 4 each). We found 320 up-regulated genes and 106 down-regulated genes (p < 0.01, 5% false discovery rate). We noted up-regulation of genes related to coagulation [tissue factor (F3) and coagulation factor II receptor-like 2 (F2RL2)] and differential regulation of genes related to F3 signaling (FOS, JUN, and NFKBIA). Results of quantitative polymerase chain reaction show a significant up-regulation of F3 after 10 and 100 microg/mLUFP exposures. Additionally, the water-soluble fractions of UFPs were sufficient to induce the expression of F3, F2RL2, and heme oxygenase 1 (HMOX1). Treatment of HPAEC with UFPs for 16 hr increased the release of interleukin (IL)-6 and IL-8. Pretreatment of HPAEC with a blocking antibody against F3 attenuated IL-6 and IL-8 release by 30 and 70%, respectively. Using gene profiling, we discovered that UFPs may induce vascular endothelial cells to express genes related to clotting. These results indicate that PM may cause adverse cardiovascular health effects by activating coagulation-inflammation circuitry. JF - Environmental health perspectives AU - Karoly, Edward D AU - Li, Zhuowei AU - Dailey, Lisa A AU - Hyseni, Xhevahire AU - Huang, Yuh-Chin T AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. karoly.edward@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 535 EP - 540 VL - 115 IS - 4 SN - 0091-6765, 0091-6765 KW - Air Pollutants KW - 0 KW - Vehicle Emissions KW - Index Medicus KW - Gene Expression Profiling KW - Vehicle Emissions -- toxicity KW - Cells, Cultured KW - Blood Coagulation -- physiology KW - Particle Size KW - Humans KW - Blood Coagulation -- drug effects KW - Pulmonary Artery -- cytology KW - Inflammation KW - Endothelial Cells -- drug effects KW - Up-Regulation -- drug effects KW - Air Pollutants -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70404687?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Up-regulation+of+tissue+factor+in+human+pulmonary+artery+endothelial+cells+after+ultrafine+particle+exposure.&rft.au=Karoly%2C+Edward+D%3BLi%2C+Zhuowei%3BDailey%2C+Lisa+A%3BHyseni%2C+Xhevahire%3BHuang%2C+Yuh-Chin+T&rft.aulast=Karoly&rft.aufirst=Edward&rft.date=2007-04-01&rft.volume=115&rft.issue=4&rft.spage=535&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-22 N1 - Date created - 2007-04-23 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):681-7 [12692008] Circulation. 1998 Dec 8;98(23):2584-90 [9843467] Carcinogenesis. 2003 Jun;24(6):1009-13 [12807741] Chest. 2003 Sep;124(3 Suppl):58S-68S [12970125] Radiat Res. 2003 Dec;160(6):637-46 [14640783] Crit Care Med. 2004 May;32(5 Suppl):S293-7 [15118533] Circulation. 2004 Jun 1;109(21):2655-71 [15173049] Genome Biol. 2004;5(10):R80 [15461798] J Clin Invest. 1999 Mar;103(6):773-8 [10079097] Nature. 1999 Apr 22;398(6729):718-23 [10227295] Blood. 1999 Jun 1;93(11):3811-23 [10339488] Arterioscler Thromb Vasc Biol. 1999 Jun;19(6):1518-25 [10364084] Blood. 2005 Jan 1;105(1):192-8 [15339841] Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):461-6 [15550696] Indoor Air. 2005 Apr;15(2):141-50 [15737157] Environ Health Perspect. 2005 Aug;113(8):1009-14 [16079071] Environ Health Perspect. 2005 Aug;113(8):1032-8 [16079075] Trends Cardiovasc Med. 2005 Oct;15(7):254-9 [16226680] Arterioscler Thromb Vasc Biol. 2005 Nov;25(11):2273-81 [16123318] Environ Health Perspect. 2005 Dec;113(12):1747-54 [16330358] Cell Biochem Funct. 2006 Mar-Apr;24(2):173-92 [15617024] Bioinformatics. 2006 Apr 1;22(7):897-9 [16455752] Circ Res. 2004 Oct 29;95(9):858-66 [15514167] J Appl Physiol (1985). 1986 Feb;60(2):532-8 [3512509] Blood. 1988 Jan;71(1):1-8 [3275472] Science. 1991 Aug 23;253(5022):909-12 [1652157] Biochemistry. 1991 Oct 29;30(43):10363-70 [1931959] N Engl J Med. 1993 Dec 9;329(24):1753-9 [8179653] Am J Respir Crit Care Med. 1997 Apr;155(4):1376-83 [9105082] Circ Res. 1998 May 4;82(8):871-8 [9580553] Mol Cell. 1998 Aug;2(2):275-81 [9734366] Environ Health Perspect. 1998 Dec;106(12):849-55 [9831546] Circulation. 2000 Mar 21;101(11):1267-73 [10725286] Crit Care Med. 2000 Sep;28(9 Suppl):S25-30 [11007193] Circulation. 2001 Jun 12;103(23):2810-5 [11401937] Occup Environ Med. 2001 Aug;58(8):511-6 [11452045] J Biol Chem. 2001 Sep 7;276(36):33428-34 [11445586] Environ Health Perspect. 2001 Aug;109 Suppl 4:483-6 [11544151] Am J Respir Crit Care Med. 2001 Nov 1;164(9):1665-8 [11719307] Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 1):1988-96 [11734456] Nucleic Acids Res. 2002 Jan 1;30(1):207-10 [11752295] Exp Lung Res. 2002 Jan-Feb;28(1):19-38 [11792073] Circulation. 2002 Jan 29;105(4):411-4 [11815420] Am J Respir Cell Mol Biol. 2002 Jun;26(6):650-8 [12034563] Blood. 2002 Jun 1;99(11):4249-50 [12043697] Environ Health Perspect. 2002 Aug;110(8):749-55 [12153754] Am J Respir Crit Care Med. 2002 Oct 1;166(7):998-1004 [12359661] J Toxicol Environ Health A. 2002 Oct 25;65(20):1531-43 [12396867] Curr Hypertens Rep. 2003 Feb;5(1):32-9 [12530933] Circulation. 2003 Feb 11;107(5):690-5 [12578870] Genome Biol. 2003;4(5):P3 [12734009] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Evaluating regional predictive capacity of a process-based mercury exposure model, regional-mercury cycling model, applied to 91 Vermont and New Hampshire lakes and ponds, USA. AN - 70400930; 17447567 AB - Regulatory agencies must develop fish consumption advisories for many lakes and rivers with limited resources. Process-based mathematical models are potentially valuable tools for developing regional fish advisories. The regional mercury cycling model (R-MCM) specifically was designed to model a series of lakes for a given region with site-specific data and parameterization for each application. In this paper, we explore the feasibility of R-MCM application to develop regional fish advisories from existing data by testing model performance across 91 Vermont ([VT], USA) and New Hampshire ([NH], USA) lakes. We use a progressive method of parameter refinement ranging from simple defaults specified by the model to site-specific parameterization to evaluate potential improvements in model prediction. Model applications and parameter refinement tiers are based on Regional Environmental Monitoring Assessment Program (REMAP) data. Results show that R-MCM generally underpredicts water column methylmercury and total mercury concentrations and overpredicts sediment methylmercury concentrations. Default level input parameterization produced the largest amount of random scatter in model forecasted values. Using site-specific values for the default level characteristics reduced this variability but did not improve overall model performance. By separating the observed and predicted data by lake characteristics, we identify some overall trends in bias and fit, but are unable to identify systematic biases in model performance by lake type. This analysis suggests that process-based models like R-MCM cannot be used for a priori predictive applications at the regional scale at this time. Further, this work reinforces the need for additional research on the transport and transformation of mercury to elucidate parameterization useable in a modeling framework to help refine predictive capabilities of process-based models. JF - Environmental toxicology and chemistry AU - Knightes, Christopher D AU - Ambrose, Robert B AD - U.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Ecosystems Research Division, Athens, Georgia 30605, USA. knightes.chris@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 807 EP - 815 VL - 26 IS - 4 SN - 0730-7268, 0730-7268 KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - New Hampshire KW - Computer Simulation KW - Forecasting KW - Vermont KW - Fresh Water -- chemistry KW - Geologic Sediments -- analysis KW - Mercury -- analysis KW - Environmental Monitoring -- standards KW - Mercury -- toxicity KW - Environmental Monitoring -- statistics & numerical data KW - Environmental Monitoring -- methods KW - Models, Theoretical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70400930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Evaluating+regional+predictive+capacity+of+a+process-based+mercury+exposure+model%2C+regional-mercury+cycling+model%2C+applied+to+91+Vermont+and+New+Hampshire+lakes+and+ponds%2C+USA.&rft.au=Knightes%2C+Christopher+D%3BAmbrose%2C+Robert+B&rft.aulast=Knightes&rft.aufirst=Christopher&rft.date=2007-04-01&rft.volume=26&rft.issue=4&rft.spage=807&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-07-27 N1 - Date created - 2007-04-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Identification of bacterial DNA markers for the detection of human fecal pollution in water. AN - 70371167; 17209067 AB - We used genome fragment enrichment and bioinformatics to identify several microbial DNA sequences with high potential for use as markers in PCR assays for detection of human fecal contamination in water. Following competitive solution-phase hybridization of total DNA from human and pig fecal samples, 351 plasmid clones were sequenced and were determined to define 289 different genomic DNA regions. These putative human-specific fecal bacterial DNA sequences were then analyzed by dot blot hybridization, which confirmed that 98% were present in the source human fecal microbial community and absent from the original pig fecal DNA extract. Comparative sequence analyses of these sequences suggested that a large number (43.5%) were predicted to encode bacterial secreted or surface-associated proteins. Deoxyoligonucleotide primers capable of annealing to a subset of 26 of the candidate sequences predicted to encode factors involved in interactions with host cells were then used in the PCR and did not amplify markers in DNA from any additional pig fecal specimens. These 26 PCR assays exhibited a range of specificity in tests with 11 other animal sources, with more than half amplifying markers only in specimens from dogs or cats. Four assays were more specific, detecting markers only in specimens from humans, including those from 18 different human populations examined. We then demonstrated the potential utility of these assays by using them to detect human fecal contamination in several impacted watersheds. JF - Applied and environmental microbiology AU - Shanks, Orin C AU - Domingo, Jorge W Santo AU - Lu, Jingrang AU - Kelty, Catherine A AU - Graham, James E AD - US Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Cincinnati, OH 45268, USA. Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 2416 EP - 2422 VL - 73 IS - 8 SN - 0099-2240, 0099-2240 KW - DNA, Bacterial KW - 0 KW - Water Pollutants KW - Index Medicus KW - Swine KW - Sensitivity and Specificity KW - Animals KW - Humans KW - Cats KW - Dogs KW - Sequence Homology KW - Nucleic Acid Hybridization KW - Computational Biology KW - Sequence Analysis, DNA KW - Feces -- microbiology KW - DNA, Bacterial -- genetics KW - Polymerase Chain Reaction -- methods KW - Water Pollutants -- isolation & purification KW - DNA, Bacterial -- analysis KW - Water Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70371167?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Identification+of+bacterial+DNA+markers+for+the+detection+of+human+fecal+pollution+in+water.&rft.au=Shanks%2C+Orin+C%3BDomingo%2C+Jorge+W+Santo%3BLu%2C+Jingrang%3BKelty%2C+Catherine+A%3BGraham%2C+James+E&rft.aulast=Shanks&rft.aufirst=Orin&rft.date=2007-04-01&rft.volume=73&rft.issue=8&rft.spage=2416&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-09 N1 - Date created - 2007-04-12 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Science. 1999 Nov 19;286(5444):1571-7 [10567266] Appl Environ Microbiol. 2006 Aug;72(8):5537-46 [16885307] Appl Environ Microbiol. 2000 Oct;66(10):4571-4 [11010920] J Mol Biol. 2001 Jan 19;305(3):567-80 [11152613] Science. 2001 Feb 2;291(5505):881-4 [11157169] Glycobiology. 2001 Feb;11(2):1R-10R [11287395] Appl Environ Microbiol. 2002 Dec;68(12):5796-803 [12450798] Environ Sci Technol. 2002 Dec 15;36(24):5279-88 [12521151] Science. 2003 Mar 28;299(5615):2074-6 [12663928] J Mol Biol. 2004 Jul 16;340(4):783-95 [15223320] Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14919-24 [15466707] Am J Epidemiol. 1982 Apr;115(4):606-16 [7072706] BMJ. 1991 Dec 7;303(6815):1444-5 [1773151] Nucleic Acids Res. 1993 Mar 11;21(5):1321-2 [8464718] Nucleic Acids Res. 1994 Nov 11;22(22):4673-80 [7984417] Nucleic Acids Res. 1997 Sep 1;25(17):3389-402 [9254694] Int J Epidemiol. 1998 Feb;27(1):1-9 [9563686] Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11554-9 [10500215] Appl Environ Microbiol. 2005 Jun;71(6):3184-91 [15933020] Appl Environ Microbiol. 2005 Aug;71(8):4945-9 [16085903] Appl Environ Microbiol. 2006 Jun;72(6):4054-60 [16751515] J Microbiol Methods. 2006 Aug;66(2):321-30 [16469400] Appl Environ Microbiol. 2000 Apr;66(4):1587-94 [10742246] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Persistence and decontamination of Bacillus atrophaeus subsp. globigii spores on corroded iron in a model drinking water system. AN - 70370079; 17308186 AB - Persistence of Bacillus atrophaeus subsp. globigii spores on corroded iron coupons in drinking water was studied using a biofilm annular reactor. Spores were inoculated at 10(6) CFU/ml in the dechlorinated reactor bulk water. The dechlorination allowed for observation of the effects of hydraulic shear and biofilm sloughing on persistence. Approximately 50% of the spores initially adhered to the corroded iron surface were not detected after 1 month. Addition of a stable 10 mg/liter free chlorine residual after 1 month led to a 2-log(10) reduction of adhered B. atrophaeus subsp. globigii, but levels on the coupons quickly stabilized thereafter. Increasing the free chlorine concentration to 25 or 70 mg/liter had no additional effect on inactivation. B. atrophaeus subsp. globigii spores injected in the presence of a typical distribution system chlorine residual (approximately 0.75 mg/liter) resulted in a steady reduction of adhered B. atrophaeus subsp. globigii over 1 month, but levels on the coupons eventually stabilized. Adding elevated chlorine levels (10, 25, and 70 mg/liter) after 1 month had no effect on the rate of inactivation. Decontamination with elevated free chlorine levels immediately after spore injection resulted in a 3-log(10) reduction within 2 weeks, but the rate of inactivation leveled off afterward. This indicates that free chlorine did not reach portions of the corroded iron surface where B. atrophaeus subsp. globigii spores had adhered. B. atrophaeus subsp. globigii spores are capable of persisting for an extended time in the presence of high levels of free chlorine. JF - Applied and environmental microbiology AU - Szabo, Jeffrey G AU - Rice, Eugene W AU - Bishop, Paul L AD - US Environmental Protection Agency, National Homeland Security Research Center, Water Infrastructure Protection Division (MS 163), Cincinnati, OH 45268, USA. szabo.jeff@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 2451 EP - 2457 VL - 73 IS - 8 SN - 0099-2240, 0099-2240 KW - Anti-Bacterial Agents KW - 0 KW - Disinfectants KW - Chlorine KW - 4R7X1O2820 KW - Iron KW - E1UOL152H7 KW - Index Medicus KW - Drinking KW - Biofilms -- drug effects KW - Anti-Bacterial Agents -- pharmacology KW - Colony Count, Microbial KW - Bacterial Adhesion KW - Chlorine -- pharmacology KW - Disinfectants -- pharmacology KW - Decontamination -- methods KW - Bacillus -- growth & development KW - Fresh Water -- microbiology KW - Spores, Bacterial -- drug effects KW - Corrosion KW - Bacillus -- drug effects KW - Water Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70370079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Persistence+and+decontamination+of+Bacillus+atrophaeus+subsp.+globigii+spores+on+corroded+iron+in+a+model+drinking+water+system.&rft.au=Szabo%2C+Jeffrey+G%3BRice%2C+Eugene+W%3BBishop%2C+Paul+L&rft.aulast=Szabo&rft.aufirst=Jeffrey&rft.date=2007-04-01&rft.volume=73&rft.issue=8&rft.spage=2451&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-09 N1 - Date created - 2007-04-12 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Emerg Infect Dis. 2004 Oct;10(10):1887-8 [15515252] J Water Health. 2004 Jun;2(2):83-96 [15387132] Appl Environ Microbiol. 1988 Feb;54(2):507-12 [3355136] Appl Environ Microbiol. 1988 Mar;54(3):649-54 [3288119] Appl Environ Microbiol. 1988 Oct;54(10):2492-9 [2849380] Appl Environ Microbiol. 1994 Dec;60(12):4339-44 [7811074] Appl Environ Microbiol. 1996 Nov;62(11):4014-8 [8899991] Lett Appl Microbiol. 1999 Feb;28(2):93-7 [10063636] Appl Environ Microbiol. 2005 Jan;71(1):566-8 [15640238] Appl Environ Microbiol. 2005 Feb;71(2):706-12 [15691920] Appl Environ Microbiol. 2005 Sep;71(9):5587-9 [16151153] Appl Microbiol Biotechnol. 2006 Sep;72(2):368-76 [16397769] Environ Sci Technol. 2006 Aug 15;40(16):4996-5002 [16955898] Lett Appl Microbiol. 2002;34(2):86-90 [11849500] Appl Environ Microbiol. 1997 Mar;63(3):978-82 [14692421] Appl Environ Microbiol. 2001 Jan;67(1):317-22 [11133461] Water Res. 2001 Apr;35(6):1624-6 [11317912] Water Sci Technol. 2001;43(12):133-8 [11464741] J Appl Microbiol. 2001 Sep;91(3):525-32 [11556920] Microbiology. 2001 Nov;147(Pt 11):3121-6 [11700362] Water Sci Technol. 2004;49(11-12):269-75 [15303751] Appl Environ Microbiol. 1987 May;53(5):1178-80 [3606094] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Concentrations of polychlorinated dibenzo-p-dioxins in processed ball clay from the United States. AN - 70263046; 17223172 AB - Processed ball clays commonly used by the ceramic art industry in the United States were collected from retail suppliers and analyzed for the presence and concentration of the 2,3,7,8-Cl substituted polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/PCDFs). The average PCDD toxic equivalent (TEQ) concentrations of these processed ball clays was approximately 800 pg/g (TEQ-WHO) with characteristic congener profiles and isomer distributions similar to patterns of previously analyzed raw and processed ball clays. The PCDF concentrations were below the average limit of detection (LOD) of 0.5 pg/g. Correlation analyses reveal no significant relationship between total organic carbon (TOC) and either individual, homologues, and total tetra-through octa-chlorinated PCDD congeners, or TEQ concentrations of the processed ball clays. The results are consistent with earlier studies on levels of PCDDs in ball clays. Data from earlier studies indicated that dioxins may be released to the environment during the processing of raw clay or the firing process used in commercial ceramic facilities. The presence of dioxin in the clays also raises concerns about potential occupational exposure for individuals involved in the mining/processing of ball clay, ceramics manufacturing and ceramic artwork. JF - Chemosphere AU - Ferrario, Joseph AU - Byrne, Christian AU - Schaum, John AD - United States Environmental Protection Agency, Office of Prevention, Pesticides, and Toxic Substances, Environmental Chemistry Laboratory, Building 1105, John C. Stennis Space Center, MS 39529, USA. ferrario.joseph@epa.gov Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 1816 EP - 1821 VL - 67 IS - 9 SN - 0045-6535, 0045-6535 KW - Aluminum Silicates KW - 0 KW - Benzofurans KW - Industrial Waste KW - Organic Chemicals KW - Polychlorinated Dibenzodioxins KW - Soil Pollutants KW - clay KW - 1302-87-0 KW - Carbon KW - 7440-44-0 KW - Index Medicus KW - United States KW - Organic Chemicals -- chemistry KW - Isomerism KW - Organic Chemicals -- analysis KW - Carbon -- analysis KW - Carbon -- chemistry KW - Polychlorinated Dibenzodioxins -- analogs & derivatives KW - Ceramics KW - Polychlorinated Dibenzodioxins -- analysis KW - Aluminum Silicates -- chemistry KW - Aluminum Silicates -- analysis KW - Benzofurans -- analysis KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70263046?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Concentrations+of+polychlorinated+dibenzo-p-dioxins+in+processed+ball+clay+from+the+United+States.&rft.au=Ferrario%2C+Joseph%3BByrne%2C+Christian%3BSchaum%2C+John&rft.aulast=Ferrario&rft.aufirst=Joseph&rft.date=2007-04-01&rft.volume=67&rft.issue=9&rft.spage=1816&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-27 N1 - Date created - 2007-03-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Bottom sediment sampling in urban settings; challenges and strategies AN - 51369207; 2007-110922 AB - Bottom sediment can be both a repository and secondary source of contaminants in aquatic systems. To define the extent and severity of contamination and identify the source and nature of the contaminants, sediment sampling was conducted in streams of the metropolitan Kansas City area. This presentation summarizes the challenges faced in locating appropriate sampling sites in the urban settings and strategies used to accomplish that task. These challenges include the presence of a wide spectrum of nonpoint sources from heterogeneous land uses, intermittent human activities, considerable stream reaches transecting a multitude of private ownerships, and extensive channel management. To ensure the appropriateness and completeness of site location, we used a process involving a review of relevant historical data (e.g., stormwater runoff monitoring data by local government), watershed reconnaissance (identifying major physical features and land use characteristics), site inspection, and pilot sampling to final sampling. The subsequent measurement results were found to meet our study objectives, which validates our site selection strategy. Because the challenges in this study should be common to other urban areas, this method will find broad application. JF - Abstracts with Programs - Geological Society of America AU - Tao, Jing AU - Huggins, Donald AU - Welker, Gary AU - Dias, Jerry AU - Murowchick, Jim AU - Anonymous Y1 - 2007/04// PY - 2007 DA - April 2007 SP - 8 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 3 SN - 0016-7592, 0016-7592 KW - United States KW - water quality KW - pollutants KW - Wyandotte County Kansas KW - water management KW - pollution KW - urban environment KW - Kansas KW - sampling KW - sediments KW - Kansas City Kansas KW - water resources KW - water pollution KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51369207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Bottom+sediment+sampling+in+urban+settings%3B+challenges+and+strategies&rft.au=Tao%2C+Jing%3BHuggins%2C+Donald%3BWelker%2C+Gary%3BDias%2C+Jerry%3BMurowchick%2C+Jim%3BAnonymous&rft.aulast=Tao&rft.aufirst=Jing&rft.date=2007-04-01&rft.volume=39&rft.issue=3&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, South-Central Section, 41st annual meeting; Geological Society of America, North-Central Section, 41st annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2007-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - Kansas; Kansas City Kansas; pollutants; pollution; sampling; sediments; United States; urban environment; water management; water pollution; water quality; water resources; Wyandotte County Kansas ER - TY - JOUR T1 - Irrigation return flow or discrete discharge? Why water pollution from cranberry bogs should fall within the clean water act's NPDES program AN - 36816744; 3504493 AB - Though not historically subject to the Clean Water Act, cranberry farms are water-intensive and frequently have negative impacts on water quality due to excessive discharges of phosphorus and pesticide residue. The authors demonstrate why a recent public nuisance lawsuit in Wisconsin against a cranberry grower proved to be largely ineffective, and argue that the NPDES permit system would provide a more efficient means to control pollution from cranberry farms, despite the 'irrigation return flow' exemption in the CWA. JF - Environmental law AU - Hanson, Andrew C AU - Bender, David C AD - US Environmental Protection Agency ; Garvey McNeil & McGillivray Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 339 EP - 364 VL - 37 IS - 2 SN - 0046-2276, 0046-2276 KW - Economics KW - Environment KW - Fertilizers KW - Cost-effectiveness KW - Natural resources KW - Irrigation KW - Water quality KW - Water pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36816744?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+law&rft.atitle=Irrigation+return+flow+or+discrete+discharge%3F+Why+water+pollution+from+cranberry+bogs+should+fall+within+the+clean+water+act%27s+NPDES+program&rft.au=Hanson%2C+Andrew+C%3BBender%2C+David+C&rft.aulast=Hanson&rft.aufirst=Andrew&rft.date=2007-04-01&rft.volume=37&rft.issue=2&rft.spage=339&rft.isbn=&rft.btitle=&rft.title=Environmental+law&rft.issn=00462276&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 6911 13490 13484 13467 9511 4309; 13476 9818; 8570; 4309; 2933 2920 971 2934 3883; 13480 13484 13467 9511 4309; 4879 757 4379 ER - TY - JOUR T1 - Sound survey designs can facilitate integrating stream monitoring data across multiple programs AN - 20919567; 7360720 AB - Multiple agencies in the Pacific Northwest monitor the condition of stream networks or their watersheds. Some agencies use a stream "network" perspective to report on the fraction or length of the network that either meets or violates particular criteria. Other agencies use a "watershed" perspective to report on the health or condition of watersheds. The agencies often use the same indicators and measurement protocols for data collection and often conduct monitoring in overlapping geographic regions. In these situations, agencies would like to combine data across different monitoring studies in a statistically sound manner to make regional estimates of condition. Three statistical survey design principles will facilitate combining such studies: (1) a clearly specified statistical target population of interest, including elements that comprise the population, (2) a consistent representation of that target population (such as a digital map of the stream network and watersheds), and (3) rules that incorporate randomization to guide the selection of the sample of sites on which measurements will be made. A case study illustrates the application of these design principles using two agency monitoring programs interested in combining stream channel data for different purposes: one for making network summaries and the other for evaluating watershed condition. JF - Journal of the American Water Resources Association AU - Larsen, D P AU - Olsen, A R AU - Lanigan, SH AU - Moyer, C AU - Jones, K K AU - Kincaid, T M AD - Pacific States Marine Fisheries Commission, c/o Western Ecology Division, National Health and Ecological Effects Research Lab, Office of Research and Development, U.S. EPA, 200 SW 35th St., Corvallis, Oregon 97333, USA, larsen.phil@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 384 EP - 397 VL - 43 IS - 2 SN - 1093-474X, 1093-474X KW - Aqualine Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Meteorological & Geoastrophysical Abstracts; Pollution Abstracts; Water Resources Abstracts KW - Statistical analysis KW - Water resources KW - Watersheds KW - Streams KW - INE, USA, Pacific Northwest KW - Networks KW - Sounds KW - Data Collections KW - Environmental monitoring KW - Data collection KW - Case Studies KW - Illustrations KW - Surveys KW - Data collections KW - Design KW - case studies KW - Channels KW - Monitoring KW - SW 5010:Network design KW - P 2000:FRESHWATER POLLUTION KW - M2 556.18:Water Management (556.18) KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - Q5 08501:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20919567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Sound+survey+designs+can+facilitate+integrating+stream+monitoring+data+across+multiple+programs&rft.au=Larsen%2C+D+P%3BOlsen%2C+A+R%3BLanigan%2C+SH%3BMoyer%2C+C%3BJones%2C+K+K%3BKincaid%2C+T+M&rft.aulast=Larsen&rft.aufirst=D&rft.date=2007-04-01&rft.volume=43&rft.issue=2&rft.spage=384&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2007.00030.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Illustrations; Water resources; Data collections; Watersheds; Statistical analysis; Channels; case studies; Data collection; Streams; Design; Case Studies; Networks; Surveys; Sounds; Monitoring; Data Collections; INE, USA, Pacific Northwest DO - http://dx.doi.org/10.1111/j.1752-1688.2007.00030.x ER - TY - JOUR T1 - New Categorical Metrics for Air Quality Model Evaluation AN - 20652363; 9395019 AB - Traditional categorical metrics used in model evaluations are 'clear cut' measures in that the model's ability to predict an 'exceedance' is defined by a fixed threshold concentration and the metrics are defined by observation-forecast sets that are paired both in space and time. These metrics are informative but limited in evaluating the performance of air quality forecast (AQF) systems because AQF generally examines exceedances on a regional scale rather than a single monitor. New categorical metrics-the weighted success index (WSI), area hit (aH), and area false-alarm ratio (aFAR)-are developed. In the calculation of WSI, credits are given to the observation-forecast pairs within the observed exceedance region (missed forecast) or the forecast exceedance region (false alarm), depending on the distance of the points from the central line (perfect observation-forecast match line or 1:1 line on scatterplot). The aH and aFAR are defined by matching observed and forecast exceedances within an area (i.e., model grid cells) surrounding the observation location. The concept of aH and aFAR resembles the manner in which forecasts are usually issued. In practice, a warning is issued for a region of interest, such as a metropolitan area, if an exceedance is forecast to occur anywhere within the region. The application of these new categorical metrics, which are supplemental to the traditional counterparts (critical success index, hit rate, and false-alarm ratio), to the Eta Model-Community Multiscale Air Quality (CMAQ) forecast system has demonstrated further insight into evaluating the forecasting capability of the system (e.g., the new metrics can provide information about how the AQF system captures the spatial variations of pollutant concentrations). JF - Journal of Applied Meteorology AU - Kang, Daiwen AU - Mathur, Rohit AU - Schere, Kenneth AU - Yu, Shaocai AU - Eder, Brian Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 549 EP - 555 PB - American Meteorological Society, 45 Beacon St. VL - 46 IS - 4 SN - 0894-8763, 0894-8763 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - spatial distribution KW - Air pollution forecasting KW - Atmospheric pollution KW - Atmospheric pollution models KW - Meteorology KW - Air quality KW - metropolitan areas KW - Clear cutting KW - Air quality models KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20652363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=New+Categorical+Metrics+for+Air+Quality+Model+Evaluation&rft.au=Kang%2C+Daiwen%3BMathur%2C+Rohit%3BSchere%2C+Kenneth%3BYu%2C+Shaocai%3BEder%2C+Brian&rft.aulast=Kang&rft.aufirst=Daiwen&rft.date=2007-04-01&rft.volume=46&rft.issue=4&rft.spage=549&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2FJAM2479.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution models; Atmospheric pollution; Air quality; Air quality models; spatial distribution; Air pollution forecasting; Meteorology; metropolitan areas; Clear cutting DO - http://dx.doi.org/10.1175/JAM2479.1 ER - TY - JOUR T1 - Partitioning Risk Among Different Causes Of Nest Failure AN - 20434795; 7767912 AB - Nest predation and nest parasitism receive the most attention as causes of nest failure for North American songbirds. Yet for many populations, interspecific competition, adverse weather, abandonment, nestling starvation, and egg failure may also be significant causes of nest failure. Despite the long interest in differential failure, serious challenges remain in the estimation of separate probabilities of nest failure from different causes. Apparent rates of failure suffer from at least two sources of bias: heterogeneous ages at discovery and classification error. We developed maximum-likelihood estimators for cause-specific daily probabilities of nest failure. We further show how the estimators can be extended to include classification error, if known. Finally, we demonstrate a simple application to Loggerhead Shrikes (Lanius ludovicianus), Tree Swallows (Tachycineta bicolor), Violet-green Swallows (T. thalassina), and Western Bluebirds (Sialia mexicana). Daily probabilities of survival were lower for the Loggherhead Shrike (0.978 plus or minus 0.004) than for any of the three cavity-nesting species (range: 0.989 plus or minus 0.002 - 0.993 plus or minus 0.001). Weather was an important cause of nest failure for Loggerhead Shrikes (0.15 plus or minus 0.05 overall). Conversely, competition among secondary cavity-nesters was not an important contributor to nest failure (range: 2-5% of nest failures) for bluebirds or swallows. Our estimator differs from others by allowing multiple fates to be modeled as separately estimated parameters rather than as covariates to a single estimated failure probability. Thus, our estimator should be viewed as an important complement to existing methods.Division del Riesgo Entre Diferentes Causas de Fracaso Durante la NidificacionOriginal Abstract: La depredacion y el parasitismo de los nidos han recibido la mayor atencion como causas de fracaso durante la nidificacion para las aves canoras de Norteamerica. Sin embargo, en muchas poblaciones la competencia interespecifica, las inclemencias del clima, el abandono, la inanicion de los polluelos y fallas de los huevos pueden ser causas significativas del fracaso de nidificacion. A pesar del amplio interes en determinar las diferentes causas de fracaso, aun existen grandes desafios en la estimacion de las probabilidades de cada causa de fracaso de nidificacion. Las tasas de fracaso aparentes tienen por lo menos dos fuentes de sesgo: edades heterogeneas de los nidos al ser descubiertos y error de clasificacion. Desarrollamos estimadores de maxima verosimilitud para probabilidades diarias especificas de cada causa de fracaso. Ademas, mostramos como incluir un error de clasificacion, si es conocido, en los estimados. Finalmente, demostramos una aplicacion simple en Lanius ludovicianus, Tachycineta bicolor, T. thalassina y Sialia mexicana. Las probabilidades diarias de supervivencia fueron mas bajas para L. ludovicianus (0.978 plus or minus 0.004) que para cualquier otra de las tres especies que nidifican en cavidades (rango: 0.989 plus or minus 0.002 - 0.993 plus or minus 0.001). El clima fue una causa importante de fracaso de nidifcacion para L. ludovicianus (0.15 plus or minus 0.05 en general). Contrariamente, la competencia entre aves no excavadoras que nidifican en cavidades no fue importante para el fracaso de nidificacion (rango: 2-5% de fracaso de nidificacion) en T. thalassina y S. mexicana. Nuestro estimado difiere de otros en que el nuestro permite modelar multiples destinos de los nidos en forma de parametros que se estiman separadamente en vez de hacerlo como covariables de un unico estimado de la probabilidad de fracaso. Por esta razon, nuestro estimado deberia ser considerado como un complemento importante de los metodos existentes. JF - Auk AU - Etterson, MA AU - Nagy, L R AU - Robinson, T R AD - U.S. Environmental Protection Agency, Office of Research and Development/NHEERL, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804, USA Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 432 EP - 443 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com], [URL:http://www.allenpress.com] VL - 124 IS - 2 SN - 0004-8038, 0004-8038 KW - Animal Behavior Abstracts; Ecology Abstracts KW - Lanius ludovicianus KW - Starvation KW - Weather KW - Classification KW - Predation KW - Survival KW - Sialia mexicana KW - Competition KW - Parasitism KW - Nests KW - Tachycineta bicolor KW - Y 25040:Behavioral Ecology KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20434795?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Auk&rft.atitle=Partitioning+Risk+Among+Different+Causes+Of+Nest+Failure&rft.au=Etterson%2C+MA%3BNagy%2C+L+R%3BRobinson%2C+T+R&rft.aulast=Etterson&rft.aufirst=MA&rft.date=2007-04-01&rft.volume=124&rft.issue=2&rft.spage=432&rft.isbn=&rft.btitle=&rft.title=Auk&rft.issn=00048038&rft_id=info:doi/10.1642%2F0004-8038%282007%291242.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0004-8038&volume=124&issue=2&page=432 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Starvation; Weather; Classification; Predation; Survival; Parasitism; Competition; Nests; Lanius ludovicianus; Sialia mexicana; Tachycineta bicolor DO - http://dx.doi.org/10.1642/0004-8038(2007)124[432:PRADCO]2.0.CO;2 ER - TY - JOUR T1 - Multiplexing siRNAs to compress RNAi-based screen size in human cells AN - 20096658; 7420647 AB - Here we describe a novel strategy using multiplexes of synthetic small interfering RNAs (siRNAs) corresponding to multiple gene targets in order to compress RNA interference (RNAi) screen size. Before investigating the practical use of this strategy, we first characterized the gene-specific RNAi induced by a large subset (258 siRNAs, 129 genes) of the entire siRNA library used in this study ( similar to 800 siRNAs, similar to 400 genes). We next demonstrated that multiplexed siRNAs could silence at least six genes to the same degree as when the genes were targeted individually. The entire library was then used in a screen in which randomly multiplexed siRNAs were assayed for their affect on cell viability. Using this strategy, several gene targets that influenced the viability of a breast cancer cell line were identified. This study suggests that the screening of randomly multiplexed siRNAs may provide an important avenue towards the identification of candidate gene targets for downstream functional analyses and may also be useful for the rapid identification of positive controls for use in novel assay systems. This approach is likely to be especially applicable where assay costs or platform limitations are prohibitive. JF - Nucleic Acids Research AU - Martin, Scott E AU - Jones, Tamara L AU - Thomas, Cheryl L AU - Lorenzi, Philip L AU - Nguyen, Dac A AU - Runfola, Timothy AU - Gunsior, Michele AU - Weinstein, John N AU - Goldsmith, Paul K AU - Lader, Eric AU - Huppi, Konrad AU - Caplen, Natasha J AD - Gene Silencing Section, Office of Science and Technology Partnership, OD, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Molecular Target Development Program, CCR, NCI-Frederick, NIH, Frederick, Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, Antibody and Protein Purification Unit, CCR, NCI, NIH, Bethesda and Qiagen Inc., Germantown, MD, USA Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - e57 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 35 IS - 8 SN - 0305-1048, 0305-1048 KW - Biotechnology and Bioengineering Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - Tumor cell lines KW - siRNA KW - RNA-mediated interference KW - Breast cancer KW - W 30905:Medical Applications KW - N 14830:RNA UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20096658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nucleic+Acids+Research&rft.atitle=Multiplexing+siRNAs+to+compress+RNAi-based+screen+size+in+human+cells&rft.au=Martin%2C+Scott+E%3BJones%2C+Tamara+L%3BThomas%2C+Cheryl+L%3BLorenzi%2C+Philip+L%3BNguyen%2C+Dac+A%3BRunfola%2C+Timothy%3BGunsior%2C+Michele%3BWeinstein%2C+John+N%3BGoldsmith%2C+Paul+K%3BLader%2C+Eric%3BHuppi%2C+Konrad%3BCaplen%2C+Natasha+J&rft.aulast=Martin&rft.aufirst=Scott&rft.date=2007-04-01&rft.volume=35&rft.issue=8&rft.spage=e57&rft.isbn=&rft.btitle=&rft.title=Nucleic+Acids+Research&rft.issn=03051048&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Tumor cell lines; siRNA; Breast cancer; RNA-mediated interference ER - TY - JOUR T1 - Desorption of arsenic from drinking water distribution system solids AN - 19968092; 7368234 AB - Previous work has shown that arsenic can accumulate in drinking water distribution system (DWDS) solids (Lytle et~al., 2004) when arsenic is present in the water. The release of arsenic back into the water through particulate transport and/or chemical release (e.g. desorption, dissolution) could result in elevated arsenic levels at the consumers' tap. The primary objective of this work was to examine the impact of pH and orthophosphate on the chemical release (i.e. desorption) of arsenic from nine DWDS solids collected from utilities located in the Midwest. Arsenic release comparisons were based on the examination of arsenic and other water quality parameters in leach water after contact with the solids over the course of 168~hours. Results showed that arsenic was released from solids and suggested that arsenic release was a result of desorption rather than dissolution. Arsenic release generally increased with increasing initial arsenic concentration in the solid and increasing pH levels (in the test range of 7 to 9). Finally, orthophosphate (3 and 5 mg PO sub(4)/L) increased arsenic release at all pH values examined. Based on the study results, utilities with measurable levels of arsenic present in their water should be aware that some water quality changes can cause arsenic release in the DWDS potentially resulting in elevated levels at the consumer's tap. JF - Environmental Monitoring and Assessment AU - Copeland, Rachel C AU - Lytle, Darren A AU - Dionysious, Dionysios D AD - NRMRL, 26 W. Martin Luther King Drive, Cincinnati, OH, USA, 45268, lytle.darren@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 523 EP - 535 PB - Springer-Verlag (Heidelberg), Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 127 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Pollution Abstracts; Sustainability Science Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - water quality KW - Particulates KW - Utilities KW - Drinking Water KW - Water Distribution Systems KW - Orthophosphates KW - pH KW - Environmental monitoring KW - Arsenic KW - Desorption KW - Leaching KW - Water Quality KW - Hydrogen Ion Concentration KW - Solids KW - Drinking water KW - P 2000:FRESHWATER POLLUTION KW - M3 1010:Issues in Sustainable Development KW - SW 3060:Water treatment and distribution KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19968092?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=Desorption+of+arsenic+from+drinking+water+distribution+system+solids&rft.au=Copeland%2C+Rachel+C%3BLytle%2C+Darren+A%3BDionysious%2C+Dionysios+D&rft.aulast=Copeland&rft.aufirst=Rachel&rft.date=2007-04-01&rft.volume=127&rft.issue=1-3&rft.spage=523&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-006-9299-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; water quality; Arsenic; Leaching; Desorption; Particulates; Drinking water; Utilities; pH; Drinking Water; Water Distribution Systems; Water Quality; Orthophosphates; Hydrogen Ion Concentration; Solids DO - http://dx.doi.org/10.1007/s10661-006-9299-1 ER - TY - JOUR T1 - Removal of added nitrate in the single, binary, and ternary systems of cotton burr compost, zerovalent iron, and sediment: Implications for groundwater nitrate remediation using permeable reactive barriers AN - 19712110; 7481636 AB - Recent research has shown that carbonaceous solid materials and zerovalent iron (Fe super(0)) may potentially be used as media in permeable reactive barriers (PRBs) to degrade groundwater nitrate via heterotrophic denitrification in the solid carbon system, and via abiotic reduction and autotrophic denitrification in the Fe super(0) system. Questions arise as whether the more expensive Fe super(0) is more effective than the less expensive carbonaceous solid materials for groundwater nitrate remediation, and whether there is any synergistic effect of mixing the two different types of materials. We carried out batch tests to study the nature and rates of removal of added nitrate in the suspensions of single, binary, and ternary systems of cotton burr compost, Peerless Fe super(0), and a sediment low in organic carbon. Cotton burr compost acted as both organic carbon source and supporting material for the growth of indigenous denitrifiers. Batch tests showed that cotton burr compost alone removed added nitrate at a greater rate than did Peerless Fe super(0) alone on an equal mass basis with a pseudo-first-order rate constant k=0.0830+/-0.0031h super(-) super(1) for cotton burr compost and a k=0.00223+/-0.00022h super(-) super(1) for Peerless Fe super(0); cotton burr compost also removed added nitrate at a faster rate than did cotton burr compost mixed with Peerless Fe super(0) and/or the sediment. Furthermore, there was no substantial accumulation of ammonium ions in the cotton burr compost system, in contrast to the systems containing Peerless Fe super(0) in which ammonium ions persisted as major products of nitrate reduction. It is concluded that cotton burr compost alone may be used as an excellent denitrification medium in a PRB for groundwater nitrate removal. Further study is needed to evaluate performance of its field applications. JF - Chemosphere AU - Su, C AU - Puls, R W AD - National Risk Management Research Laboratory, Office of Research and Development, United States Environmental Protection Agency, 919 Kerr Research Drive, Ada, OK 74820, USA, su.chunming@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 1653 EP - 1662 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 67 IS - 8 SN - 0045-6535, 0045-6535 KW - Aqualine Abstracts; Water Resources Abstracts; Pollution Abstracts KW - Cotton KW - Bioremediation KW - Groundwater Barriers KW - Pollution prevention KW - Organic carbon KW - Groundwater Pollution KW - Carbon KW - Denitrification KW - Sediment Contamination KW - Compost KW - Sediment pollution KW - Ions KW - Ammonium KW - Water Pollution Treatment KW - Nitrates KW - Solids KW - Groundwater KW - Iron KW - AQ 00001:Water Resources and Supplies KW - P 2000:FRESHWATER POLLUTION KW - SW 0870:Erosion and sedimentation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19712110?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Removal+of+added+nitrate+in+the+single%2C+binary%2C+and+ternary+systems+of+cotton+burr+compost%2C+zerovalent+iron%2C+and+sediment%3A+Implications+for+groundwater+nitrate+remediation+using+permeable+reactive+barriers&rft.au=Su%2C+C%3BPuls%2C+R+W&rft.aulast=Su&rft.aufirst=C&rft.date=2007-04-01&rft.volume=67&rft.issue=8&rft.spage=1653&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2006.09.059 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Compost; Ammonium; Ions; Sediment pollution; Carbon; Bioremediation; Cotton; Nitrates; Pollution prevention; Denitrification; Organic carbon; Iron; Groundwater Barriers; Water Pollution Treatment; Sediment Contamination; Solids; Groundwater Pollution; Groundwater DO - http://dx.doi.org/10.1016/j.chemosphere.2006.09.059 ER - TY - JOUR T1 - On the sustainability of an integrated model system with industrial, ecological, and macroeconomic components AN - 19708192; 7496284 AB - The issue of sustainability has arisen naturally from the observation that a growing human population is consuming ever increasing amounts of limited natural resources and causing a host of environmental impacts. The management of environmental impacts that are the result of human activities requires an understanding of various forces on a global scale. To begin this process of understanding, we have constructed a simple model system that is closed to mass but open to a non-limiting source of energy. The system includes a resource pool, three plants species, three herbivore species, two carnivore species, a human population, a generalized industrial sector, and an inaccessible resource pool meant to represent polluted or otherwise biologically inaccessible mass. There is also a price-setting macroeconomic model regulating one of the plant species, one of the herbivores, the industrial sector, and the human population. This model system is essentially a very aggregated and simplified mini-world. We use this model system to explore the sustainability of some observed trends in the real world such as increasing material consumption by the human population. We also explore and contrast several industrial policy options including the use of bio-based production versus non-renewable based production. We further consider industrial policy options that could be used to manage environmental impacts. JF - Resources, Conservation and Recycling AU - Cabezas, H AU - Whitmore, H W AU - Pawlowski, C W AU - Mayer, AL AD - Office of Research and Development, National Risk Management Research Laboratory, 26 West Martin Luther King Drive, Cincinnati, OH 45268, USA, cabezas.heriberto@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 122 EP - 129 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 50 IS - 2 SN - 0921-3449, 0921-3449 KW - Sustainability Science Abstracts KW - herbivores KW - carnivores KW - Natural resources KW - Environmental impact KW - Conservation KW - sustainability KW - human populations KW - Recycling KW - Waste management KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19708192?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Resources%2C+Conservation+and+Recycling&rft.atitle=On+the+sustainability+of+an+integrated+model+system+with+industrial%2C+ecological%2C+and+macroeconomic+components&rft.au=Cabezas%2C+H%3BWhitmore%2C+H+W%3BPawlowski%2C+C+W%3BMayer%2C+AL&rft.aulast=Cabezas&rft.aufirst=H&rft.date=2007-04-01&rft.volume=50&rft.issue=2&rft.spage=122&rft.isbn=&rft.btitle=&rft.title=Resources%2C+Conservation+and+Recycling&rft.issn=09213449&rft_id=info:doi/10.1016%2Fj.resconrec.2006.06.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-08-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - herbivores; carnivores; Natural resources; Environmental impact; Conservation; sustainability; human populations; Recycling; Waste management DO - http://dx.doi.org/10.1016/j.resconrec.2006.06.011 ER - TY - JOUR T1 - Integrating epidemiology and toxicology in neurotoxicity risk assessment AN - 19651587; 7400711 AB - Neurotoxicity risk assessments depend on the best available scientific information, including data from animal toxicity studies, human experimental studies and human epidemiology studies. There are several factors to consider when evaluating the comparability of data from studies. Regarding the epidemiology literature, issues include choice of study design, use of appropriate controls, methods of exposure assessment, subjective or objective evaluation of neurological status, and assessment and statistical control of potential confounding factors, including co-exposure to other agents. Animal experiments must be evaluated regarding factors such as dose level and duration, procedures used to assess neurological or behavioural status, and appropriateness of inference from the animal model to human neurotoxicity. Major factors that may explain apparent differences between animal and human studies include: animal neurological status may be evaluated with different procedures than those used in humans; animal studies may involve shorter exposure durations and higher dose levels; and most animal studies evaluate a single substance whereas humans typically are exposed to multiple agents. The comparability of measured outcomes in animals and humans may be improved by considering functional domains rather than individual test measures. The application of predictive models, weight of evidence considerations and meta-analysis can help evaluate the consistency of outcomes across studies. An appropriate blend of scientific information from toxicology and epidemiology studies is necessary to evaluate potential human risks of exposure to neurotoxic substances. JF - Human & Experimental Toxicology AU - Boyes, W K AU - Moser, V C AU - Geller, A M AU - Benignus, V A AU - Bushnell, P J AU - Kamel, F AD - B105-05, Neurotoxicology Division, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA, boyes.william@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 283 EP - 293 VL - 26 IS - 4 SN - 0960-3271, 0960-3271 KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - Risk assessment KW - Data processing KW - Statistics KW - Epidemiology KW - Reviews KW - Neurotoxicity KW - Animal models KW - N3 11028:Neuropharmacology & toxicology KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19651587?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+%26+Experimental+Toxicology&rft.atitle=Integrating+epidemiology+and+toxicology+in+neurotoxicity+risk+assessment&rft.au=Boyes%2C+W+K%3BMoser%2C+V+C%3BGeller%2C+A+M%3BBenignus%2C+V+A%3BBushnell%2C+P+J%3BKamel%2C+F&rft.aulast=Boyes&rft.aufirst=W&rft.date=2007-04-01&rft.volume=26&rft.issue=4&rft.spage=283&rft.isbn=&rft.btitle=&rft.title=Human+%26+Experimental+Toxicology&rft.issn=09603271&rft_id=info:doi/10.1177%2F0960327106070481 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Statistics; Data processing; Epidemiology; Reviews; Neurotoxicity; Animal models DO - http://dx.doi.org/10.1177/0960327106070481 ER - TY - JOUR T1 - Animal models of chronic pesticide neurotoxicity AN - 19650020; 7400715 AB - There is a wealth of literature on neurotoxicological outcomes of acute and short-term exposure to pesticides in laboratory animals, but there are relatively few studies of long-term exposure. Many reports in the literature describing 'chronic' exposures to pesticides are, in fact, as short as five days and rarely longer than three months. Furthermore, routes of administration range from subcutaneous to dietary. Doses used in many of the studies produce signs of acute or overt toxicity. In contrast, human symptoms have been reported following exposures that are prolonged and often without obvious toxic effects. A survey of the literature was conducted to identify rodent studies with neurobehavioral and neurophysiological endpoints of pesticide exposures lasting 30 days or longer. This survey indicated that the majority of studies concentrate on cholinesterase inhibitors (organophosphorus and carbamate insecticides). Various neuromotor, cholinergic, physiological, affective and cognitive disorders were reported at doses producing cholinesterase inhibition; however, there were a fewer effects at non-inhibiting doses. Other classes of pesticides produced similar effects, with the exception of cholinergic signs. In many studies, the changes were subtle, which may correspond to the nonspecific changes in psychomotor and cognitive function reported in humans. It appears, then, that the data from animal and human pesticide exposures are generally comparable, but the specific outcomes are influenced by many experimental differences. Future research should concentrate on analogous exposures and outcomes to facilitate interpretation. JF - Human & Experimental Toxicology AU - Moser, V C AD - NTD (MD B105-04), US EPA, RTP, NC 27711, USA, Moser.ginger@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 321 EP - 331 VL - 26 IS - 4 SN - 0960-3271, 0960-3271 KW - Toxicology Abstracts KW - Insecticides KW - Cognitive ability KW - Chronic exposure KW - Pesticides KW - Neurotoxicity KW - Laboratory animals KW - Animal models KW - Cholinesterase KW - Pesticides (carbamates) KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19650020?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+%26+Experimental+Toxicology&rft.atitle=Animal+models+of+chronic+pesticide+neurotoxicity&rft.au=Moser%2C+V+C&rft.aulast=Moser&rft.aufirst=V&rft.date=2007-04-01&rft.volume=26&rft.issue=4&rft.spage=321&rft.isbn=&rft.btitle=&rft.title=Human+%26+Experimental+Toxicology&rft.issn=09603271&rft_id=info:doi/10.1177%2F0960327106072395 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Insecticides; Chronic exposure; Cognitive ability; Neurotoxicity; Pesticides; Animal models; Laboratory animals; Pesticides (carbamates); Cholinesterase DO - http://dx.doi.org/10.1177/0960327106072395 ER - TY - JOUR T1 - Speciation of organotins in polyvinyl chloride pipe via X-ray absorption spectroscopy and in leachates using GC-PFPD after derivatisation AN - 19649911; 7401115 AB - Three different polyvinyl chloride (PVC) pipe types were subjected to de-ionized water exposures over the course of at least 180 days. Water exposed to the pipe was analyzed for organotin speciation and concentration. Organotin concentrations were the highest during the first 1-5 days. The species and concentrations of organotins leached varied by pipe type. Data were normalized by surface area in order to compare laboratory results with results from a residential pipe system. For one pipe type, the lowest non-zero concentrations from the laboratory tests overestimated organotin concentrations in solution when compared with water samples from the same pipe type in a residence. For organotin exposure estimates, a range of 0.1 ng m super(-2) to 10 ng m super(-2) could be used for mature pipes (e.g. in use for 1 year). These estimates should be refined with more field study, however, due to the high variation in organotin species and concentrations leached as a function of pipe type, accuracy within an order of magnitude may be optimal as, in many instances, the type of pipe installed or buried may be unknown. X-ray absorption spectroscopy (XAS) was used to identify organic and inorganic tin species in reference materials and the PVC samples. Monobutyl tin was identified as the primary organotin species in the pipes. Results from the XAS analyses also indicate that the technique shows promise for distinguishing between inorganic tin and organotins. Furthermore, organotins may be distinguished between mono-, di-, and tri-ligand species using XAS. JF - Journal of Environmental Monitoring AU - Impellitteri, CA AU - Evans, O AU - Ravel, B AD - US Environmental Protection Agency, National Risk Management Research Laboratory, 26 West Martin Luther King Drive, Cincinnati, OH 45268, USA, Impellitteri.christopher@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 358 EP - 365 VL - 9 IS - 4 SN - 1464-0325, 1464-0325 KW - Pollution Abstracts KW - Environmental monitoring KW - Pipes KW - Absorption spectroscopy KW - Leaching KW - Water sampling KW - Laboratory testing KW - Chlorides KW - Tin KW - Leachates KW - surface area KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19649911?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Speciation+of+organotins+in+polyvinyl+chloride+pipe+via+X-ray+absorption+spectroscopy+and+in+leachates+using+GC-PFPD+after+derivatisation&rft.au=Impellitteri%2C+CA%3BEvans%2C+O%3BRavel%2C+B&rft.aulast=Impellitteri&rft.aufirst=CA&rft.date=2007-04-01&rft.volume=9&rft.issue=4&rft.spage=358&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fb617711e LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Pipes; Absorption spectroscopy; Leaching; Laboratory testing; Water sampling; Chlorides; Tin; Leachates; surface area DO - http://dx.doi.org/10.1039/b617711e ER - TY - JOUR T1 - Temporal change in forest fragmentation at multiple scales AN - 19631926; 7380218 AB - Previous studies of temporal changes in fragmentation have focused almost exclusively on patch and edge statistics, which might not detect changes in the spatial scale at which forest occurs in or dominates the landscape. We used temporal land-cover data for the Chesapeake Bay region and the state of New Jersey to compare patch-based and area-density scaling measures of fragmentation for detecting changes in the spatial scale of forest that may result from forest loss. For the patch-based analysis, we examined changes in the cumulative distribution of patch sizes. For area-density scaling, we used moving windows to examine changes in dominant forest. We defined dominant forest as a forest parcel (pixel) surrounded by a neighborhood in which forest occupied the majority of pixels. We used >50% and greater than or equal to 60% as thresholds to define majority. Moving window sizes ranged from 2.25 to 5,314.41 hectares (ha). Patch size cumulative distributions changed very little over time, providing no indication that forest loss was changing the spatial scale of forest. Area-density scaling showed that dominant forest was sensitive to forest loss, and the sensitivity increased nonlinearly as the spatial scale increased. The ratio of dominant forest loss to forest loss increased nonlinearly from 1.4 to 1.8 at the smallest spatial scale to 8.3 to 11.5 at the largest spatial scale. The nonlinear relationship between dominant forest loss and forest loss in these regions suggests that continued forest loss will cause abrupt transitions in the scale at which forest dominates the landscape. In comparison to the Chesapeake Bay region, dominant forest loss in New Jersey was less sensitive to forest loss, which may be attributable the protected status of the New Jersey Pine Barrens. JF - Landscape Ecology AU - Wickham, J D AU - Riitters, KH AU - Wade, T G AU - Coulston, J W AD - U.S. Environmental Protection Agency (E243-05), Research Triangle Park, NC, 27711, USA, wickham.james@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 481 EP - 489 PB - Springer-Verlag (Heidelberg), Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 22 IS - 4 SN - 0921-2973, 0921-2973 KW - Sustainability Science Abstracts; Ecology Abstracts KW - Landscape KW - Statistical analysis KW - Forests KW - Scaling KW - Habitat fragmentation KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19631926?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Landscape+Ecology&rft.atitle=Temporal+change+in+forest+fragmentation+at+multiple+scales&rft.au=Wickham%2C+J+D%3BRiitters%2C+KH%3BWade%2C+T+G%3BCoulston%2C+J+W&rft.aulast=Wickham&rft.aufirst=J&rft.date=2007-04-01&rft.volume=22&rft.issue=4&rft.spage=481&rft.isbn=&rft.btitle=&rft.title=Landscape+Ecology&rft.issn=09212973&rft_id=info:doi/10.1007%2Fs10980-006-9054-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Landscape; Statistical analysis; Forests; Habitat fragmentation; Scaling DO - http://dx.doi.org/10.1007/s10980-006-9054-6 ER - TY - JOUR T1 - Ontogenetic Alterations in Molecular and Structural Correlates of Dendritic Growth after Developmental Exposure to Polychlorinated Biphenyls AN - 19627096; 7355660 AB - OBJECTIVE: Perinatal exposure to polychlorinated biphenyls (PCBs) is associated with decreased IQ scores, impaired learning and memory, psychomotor difficulties, and attentional deficits in children. It is postulated that these neuropsychological deficits reflect altered patterns of neuronal connectivity. To test this hypothesis, we examined the effects of developmental PCB exposure on dendritic growth. METHODS: Rat dams were gavaged from gestational day 6 through postnatal day (PND) 21 with vehicle (corn oil) or the commercial PCB mixture Aroclor 1254 (6 mg/kg/day). Dendritic growth and molecular markers were examined in pups during development. RESULTS: Golgi analyses of CA1 hippocampal pyramidal neurons and cerebellar Purkinge cells indicated that developmental exposure to PCBs caused a pronounced age-related increase in dendritic growth. Thus, even though dendritic lengths were significantly attenuated in PCB-treated animals at PND22, the rate of growth was accelerated at later ages such that by PND60, dendritic growth was comparable to or even exceeded that observed in vehicle controls. Quantitative reverse transcriptase polymerase chain reaction analyses demonstrated that from PND4 through PND21, PCBs generally increased expression of both spinophilin and RC3/neurogranin mRNA in the hippocampus, cerebellum, and cortex with the most significant increases observed in the cortex. CONCLUSIONS: This study demonstrates that developmental PCB exposure alters the ontogenetic profile of dendritogenesis in critical brain regions, supporting the hypothesis that disruption of neuronal connectivity contributes to neuropsychological deficits seen in exposed children. JF - Environmental Health Perspectives AU - Lein, P J AU - Yang, D AU - Bachstetter, AD AU - Tilson, HA AU - Harry, G J AU - Mervis, R F AU - Kodavanti, PRS AD - Cellular and Molecular Toxicology Branch, Neurotoxicology Division, B 105-06, NHEERL/ORD, U.S. EPA, Research Triangle Park, NC 27711 USA, kodavanti.prasada@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 556 EP - 563 VL - 115 IS - 4 SN - 0091-6765, 0091-6765 KW - Pollution Abstracts; Toxicology Abstracts KW - Spinophilin KW - Golgi apparatus KW - Age KW - Hippocampus KW - Cerebellum KW - Development KW - corn KW - Oil KW - Growth KW - Memory KW - Cortex KW - Perinatal exposure KW - Dams KW - Polymerase chain reaction KW - Ontogeny KW - RNA-directed DNA polymerase KW - Aroclor 1254 KW - PCB compounds KW - PCB KW - intelligence KW - Learning KW - Neural networks KW - Brain KW - Children KW - Neurogranin KW - Intelligence KW - polychlorinated biphenyls KW - Pyramidal cells KW - Attention KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19627096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Ontogenetic+Alterations+in+Molecular+and+Structural+Correlates+of+Dendritic+Growth+after+Developmental+Exposure+to+Polychlorinated+Biphenyls&rft.au=Lein%2C+P+J%3BYang%2C+D%3BBachstetter%2C+AD%3BTilson%2C+HA%3BHarry%2C+G+J%3BMervis%2C+R+F%3BKodavanti%2C+PRS&rft.aulast=Lein&rft.aufirst=P&rft.date=2007-04-01&rft.volume=115&rft.issue=4&rft.spage=556&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.9773 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Golgi apparatus; Spinophilin; Learning; Neural networks; Hippocampus; Brain; Cerebellum; Development; Children; Neurogranin; Oil; Intelligence; Memory; polychlorinated biphenyls; Cortex; Perinatal exposure; Dams; RNA-directed DNA polymerase; Ontogeny; Polymerase chain reaction; Aroclor 1254; Attention; Pyramidal cells; PCB; Age; Growth; PCB compounds; corn; intelligence DO - http://dx.doi.org/10.1289/ehp.9773 ER - TY - JOUR T1 - Mammary Gland Development as a Sensitive End Point after Acute Prenatal Exposure to an Atrazine Metabolite Mixture in Female Long-Evans Rats AN - 19625693; 7355658 AB - BACKGROUND: Atrazine (ATR), a widely used chlorotriazine herbicide, inhibits a number of endocrine-dependent processes, including gonadotrophin surges and mammary gland development in rats. Chlorotriazine herbicides are rapidly metabolized in plants and animals to form a group of metabolites that are detected both in the environment and in exposed animals. The extent to which these metabolites are responsible direcdy for the observed health effects is not understood. OBJECTIVES: Our goal was to determine if a mixture of ATR metabolites, in proportions found in the environment, might produce developmental effects in Long-Evans rats following exposure late in pregnancy. METHODS: We administered an ATR metabolite mixture (AMM) containing ATR, hydroxyatrazine, diaminochlorotriazine, deethylatrazine, and deisopropylatrazine orally to pregnant Long-Evans rats at 0.09, 0.87, or 8.73 mg/kg body weight (bw)/day, on gestation days 15-19, using 0 and 100 mg ATR/kg bw/day as negative and positive controls, respectively. RESULTS: We observed no significant effect of acute AMM exposure on body weight gain in dams during the dosing period, weight loss in pups on postnatal day (PND)4, or pubertal timing, as is seen with ATR alone. However, as with ATR, we detected delayed mammary gland development, evaluated by whole mount analysis, as early as PND4 in all treatment groups. CONCLUSIONS: Our data suggest that acute exposure to AMM at levels as low as 0-09 mg/kg bw during late pregnancy causes persistent alterations in mammary gland development of female offspring, and that these effects do not appear to be related to bw or associated with pubertal timing. JF - Environmental Health Perspectives AU - Enoch, R R AU - Stanko, J P AU - Greiner, S N AU - Younghlood, G L AU - Rayner, J L AU - Fenton, SE AD - U.S. Environmental Protection Agency, Reproductive Toxicology Division, 2525 Hwy 54, MD-67, Research Triangle Park, NC 27713 USA, fenton.suzanne@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 541 EP - 547 VL - 115 IS - 4 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - Prenatal experience KW - Mammary gland KW - Atrazine KW - Gestation KW - Metabolites KW - Herbicides KW - Progeny KW - Development KW - Pituitary (anterior) KW - Body weight gain KW - Pregnancy KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19625693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Mammary+Gland+Development+as+a+Sensitive+End+Point+after+Acute+Prenatal+Exposure+to+an+Atrazine+Metabolite+Mixture+in+Female+Long-Evans+Rats&rft.au=Enoch%2C+R+R%3BStanko%2C+J+P%3BGreiner%2C+S+N%3BYounghlood%2C+G+L%3BRayner%2C+J+L%3BFenton%2C+SE&rft.aulast=Enoch&rft.aufirst=R&rft.date=2007-04-01&rft.volume=115&rft.issue=4&rft.spage=541&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.9612 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Prenatal experience; Mammary gland; Gestation; Atrazine; Progeny; Herbicides; Metabolites; Development; Body weight gain; Pituitary (anterior); Pregnancy DO - http://dx.doi.org/10.1289/ehp.9612 ER - TY - JOUR T1 - Biodiesel Exhaust: The Need for Health Effects Research AN - 19622240; 7355650 AB - BACKGROUND: Biodiesel is a diesel fuel alternative that has shown potential of becoming a commercially accepted part of the United States' energy infrastructure. In November 2004, the signing of the Jobs Creation Bill HR 4520 marked an important turning point for the future production of biodiesel in the United States because it offers a federal excise tax credit. By the end of 2005, industry production was 75 million gallons, a 300% increase in 1 year. Current industry capacity, however, stands at just over 300 million gallons/year, and current expansion and new plant construction could double the industry's capacity within a few years. Biodiesel exhaust emission has been extensively characterized under field and laboratory conditions, but there have been limited cytotoxicity and mutagenicity studies on the effects of biodiesel exhaust in biologic systems. OBJECTIVES: We reviewed pertinent medical literature and addressed recommendations on testing specific research needs in the field of biodiesel toxicity. DISCUSSION: Employment of biodiesel fuel is favorably viewed, and there are suggestions that its exhaust emissions are less likely to present any risk to human health relative to petroleum diesel emissions. CONCLUSION: The speculative nature of a reduction in health effects based on chemical composition of biodiesel exhaust needs to be followed up with investigations in biologic systems. JF - Environmental Health Perspectives AU - Swanson, K J AU - Madden, M C AU - Ghio, A J AD - Human Studies Division, NHEERL, U.S. EPA, Research Triangle Park, NC 27711 USA, ghio.andy@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 496 EP - 499 VL - 115 IS - 4 SN - 0091-6765, 0091-6765 KW - biodiesel fuels KW - Risk Abstracts; Toxicology Abstracts; Health & Safety Science Abstracts; Pollution Abstracts KW - Mutagenicity KW - Chemical composition KW - Fuels KW - Environmental health KW - Pollution effects KW - Toxicity KW - Exhausts KW - USA KW - Cytotoxicity KW - Petroleum KW - Reviews KW - Energy KW - Emissions KW - Diesel KW - Exhaust emissions KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19622240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Biodiesel+Exhaust%3A+The+Need+for+Health+Effects+Research&rft.au=Swanson%2C+K+J%3BMadden%2C+M+C%3BGhio%2C+A+J&rft.aulast=Swanson&rft.aufirst=K&rft.date=2007-04-01&rft.volume=115&rft.issue=4&rft.spage=496&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.9631 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Cytotoxicity; Mutagenicity; Energy; Reviews; Petroleum; Fuels; Diesel; Toxicity; Exhausts; Chemical composition; Emissions; Pollution effects; Environmental health; Exhaust emissions; USA DO - http://dx.doi.org/10.1289/ehp.9631 ER - TY - JOUR T1 - Prenatal Testosterone Exposure Permanently Masculinizes Anogenital Distance, Nipple Development, and Reproductive Tract Morphology in Female Sprague-Dawley Rats AN - 19615840; 7340728 AB - In mammals, abnormal increases in fetal androgens disrupt normal development of the female phenotype. Due to the recent concern regarding environmental androgen-active chemicals, there is a need to identify sources of fetal androgen variation and sensitive developmental markers for androgenic activity in female rats. Anogenital distances (AGD), nipple retention, reproductive tract, and external genitalia are morphological parameters organized by prenatal androgens and are predictive of altered masculinized/defeminized phenotype in adult female mice and rats. The objectives of this study were to (1) characterize the natural prenatal androgen environment of rats including the magnitude of the intrauterine position (IUP) effect, (2) characterize the permanent effects of prenatal androgen exposure on female rats, and (3) determine the ability of AGD and areolas to predict these permanent androgenic alterations in female rats. Untreated male fetal rats had higher tissue testosterone (T) concentrations than females in the amniotic fluid, reproductive tract, gonad, and fetal body. The intrauterine position (IUP) of male and female fetuses did not affect T concentrations or AGD in male or female rats at gestational day (GD) 22. Female offspring exposed to 0, 1.5, and 2.5 mg/kg/day testosterone propionate (TP) on GDs 14-18 displayed increased AGD at postnatal day (PND) 2 and decreased nipples at PND 13 and as adults. TP-induced changes in neonatal AGD and infant areola number were reliable indicators of permanently altered adult phenotype in female rats. Further, females in the two high-dose groups displayed increased incidences of external genital malformations and the presence of prostatic tissue, not normally found in female rats. JF - Toxicological Sciences AU - Hotchkiss, Andrew K AU - Lambright, Christy S AU - Ostby, Joseph S AU - Parks-Saldutti, Louise AU - Vandenbergh, John G AU - Gray, Leon EJr AD - Department of Zoology, North Carolina State University, Raleigh, North Carolina 27695. Reproductive Toxicology Division, Endocrinology Branch, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711. USEPA/NCSU Cooperative Training agreement, Raleigh, North Carolina 27695. Merck Research Laboratories, West Point, Pennsylvania 19486 Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 335 EP - 345 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 96 IS - 2 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Amniotic fluid KW - Prenatal experience KW - Anogenital KW - Genitalia KW - Development KW - Fetuses KW - Testosterone KW - Nipples KW - Intrauterine position KW - Gonads KW - Progeny KW - Neonates KW - testosterone propionate KW - Infants KW - Androgens KW - X 24310:Pharmaceuticals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19615840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Prenatal+Testosterone+Exposure+Permanently+Masculinizes+Anogenital+Distance%2C+Nipple+Development%2C+and+Reproductive+Tract+Morphology+in+Female+Sprague-Dawley+Rats&rft.au=Hotchkiss%2C+Andrew+K%3BLambright%2C+Christy+S%3BOstby%2C+Joseph+S%3BParks-Saldutti%2C+Louise%3BVandenbergh%2C+John+G%3BGray%2C+Leon+EJr&rft.aulast=Hotchkiss&rft.aufirst=Andrew&rft.date=2007-04-01&rft.volume=96&rft.issue=2&rft.spage=335&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Amniotic fluid; Prenatal experience; Anogenital; Genitalia; Development; Fetuses; Nipples; Testosterone; Intrauterine position; Progeny; Gonads; Neonates; testosterone propionate; Androgens; Infants ER - TY - JOUR T1 - Bacterial preferences of the bacterivorous soil nematode Cephalobus brevicauda (Cephalobidae): Effect of bacterial type and size AN - 19611027; 8586144 AB - Cell size and type may affect availability of bacteria for consumption by bacterivorous nematodes in the soil and in culture. This study explored the bacterial preferences of the bacterivorous soil nematode Cephalobus brevicauda (Cephalobidae) by comparing bacteria isolated directly from soil, from commercial bacterial biological control agents, and from in vitro soil nematode cultures. The 16S rRNA sequences of bacterial isolates were compared to known sequences to identify phylogenetic affiliations. Bacterial preference of the nematode was observed by counting the number of Cephalobus brevicauda that were attracted to paired bacteria in a bioassay. Additionally, the reproductive output of single females reared on the bacteria was recorded. An attraction index established that Cephalobus brevicauda preferred Gram- negative, small-celled bacteria; however, Gram-positive bacteria supported maximum reproductive success. Bacterial biocontrol agents had no negative effects on reproduction, but Cephalobus brevicauda always preferred bacteria other than Dipel (Bacillus thuringiensis ssp. kurstaki), in the bacterial preference assay. JF - Pedobiologia AU - Salinas, Kimberly A AU - Edenborn, Sherie L AU - Sexstone, Alan J AU - Kotcon, James B AD - US EPA Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, FL 32561, USA, salinas.kimberly@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 55 EP - 64 PB - Elsevier GmbH, Office Jena, P.O. Box 100537 Jena D-07705 Germany, [mailto:journals@elsevier.com], [URL:http://www.elsevier.de/] VL - 51 IS - 1 SN - 0031-4056, 0031-4056 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology; Ecology Abstracts; Animal Behavior Abstracts KW - Bacterivorous nematodes KW - Cephalobus brevicauda KW - Biocontrol bacteria KW - Bacterial preference KW - Bacillus subtilis KW - Bacillus thuringiensis KW - Biological control KW - Phylogeny KW - Gram-positive bacteria KW - Cell culture KW - Enumeration KW - Soil microorganisms KW - Soil KW - Cephalobidae KW - Cell size KW - Reproduction KW - Cephalobus KW - rRNA 16S KW - Nematoda KW - Breeding success KW - Y 25020:Territory, Reproduction and Sociality KW - A 01370:Biological Control KW - J 02450:Ecology KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19611027?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pedobiologia&rft.atitle=Bacterial+preferences+of+the+bacterivorous+soil+nematode+Cephalobus+brevicauda+%28Cephalobidae%29%3A+Effect+of+bacterial+type+and+size&rft.au=Salinas%2C+Kimberly+A%3BEdenborn%2C+Sherie+L%3BSexstone%2C+Alan+J%3BKotcon%2C+James+B&rft.aulast=Salinas&rft.aufirst=Kimberly&rft.date=2007-04-01&rft.volume=51&rft.issue=1&rft.spage=55&rft.isbn=&rft.btitle=&rft.title=Pedobiologia&rft.issn=00314056&rft_id=info:doi/10.1016%2Fj.pedobi.2006.12.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Phylogeny; Soil; Biological control; Gram-positive bacteria; Cell size; Reproduction; Cell culture; Enumeration; rRNA 16S; Breeding success; Soil microorganisms; Cephalobidae; Bacillus thuringiensis; Cephalobus; Nematoda DO - http://dx.doi.org/10.1016/j.pedobi.2006.12.003 ER - TY - JOUR T1 - Evidence for Phytodegradation of MTBE from Coupled Bench-Scale and Intermediate-Scale Tests AN - 19610961; 7329978 AB - This paper presents methodologies and demonstrates the need to couple bench-scale and intermediate tree-scale experiments, to fully understand the transport and fate of organic contaminants, specifically methyl tert butyl ether (MTBE), in mature trees. Bench-scale experiments showed MTBE to be optimally taken up by small poplar saplings with a transpiration stream concentration factor of approximately 1, little or no degradation in soils and, nearly 100 plus or minus 20% recovery in the coupled water-plant-air system, indicating no measurable phytodegradation at the bench-scale. A large 14 ft tree chamber was designed to evaluate MTBE transport and fate through intermediate-scale (12 ft tall) poplar trees. Abiotic MTBE volatilization tests conducted in the tree chamber showed 100 plus or minus 20% MTBE mass recovery, thereby demonstrating the integrity of the large chamber and its air monitoring technique. In contrast, replicate intermediate-scale experiments conducted with large (12 ft) trees irrigated with a known mass of MTBE showed a deficit of MTBE mass recovery (65 plus or minus 20%) in replicate soil-tree-air systems monitored over a 2-week period. More significantly, tert butyl alcohol (TBA), a degradation product of MTBE, was detected in increasing concentrations in leaf biomass while MTBE concentrations in leaf biomass decreased as the experiment progressed. The MTBE mass recovery deficit, coupled with the detection of increasing TBA in leaf biomass, provides preliminary evidence of MTBE degradation in mature trees. JF - Journal of Environmental Engineering AU - Rubin, E G AU - Ramaswami, A AD - U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., Mail Code 5102G, Washington, D.C. 20460, USA, rubin.ellen@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 389 EP - 396 VL - 133 IS - 4 SN - 0733-9372, 0733-9372 KW - Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Soil remediation KW - Water Pollution KW - Pollution monitoring KW - Degradation KW - Trees KW - MTBE KW - Streams KW - Phytoremediation KW - Ethers KW - Testing Procedures KW - Alcohol KW - Soil contamination KW - Biomass KW - Transpiration KW - Monitoring KW - AQ 00007:Industrial Effluents KW - P 5000:LAND POLLUTION KW - SW 3020:Sources and fate of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19610961?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Engineering&rft.atitle=Evidence+for+Phytodegradation+of+MTBE+from+Coupled+Bench-Scale+and+Intermediate-Scale+Tests&rft.au=Rubin%2C+E+G%3BRamaswami%2C+A&rft.aulast=Rubin&rft.aufirst=E&rft.date=2007-04-01&rft.volume=133&rft.issue=4&rft.spage=389&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Engineering&rft.issn=07339372&rft_id=info:doi/10.1061%2F%28ASCE%290733-9372%282007%29133%3A4%28389%29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-04-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Soil remediation; Pollution monitoring; Alcohol; Phytoremediation; Trees; MTBE; Ethers; Soil contamination; Biomass; Testing Procedures; Water Pollution; Degradation; Monitoring; Transpiration; Streams DO - http://dx.doi.org/10.1061/(ASCE)0733-9372(2007)133:4(389) ER - TY - JOUR T1 - Interannual variation in meteorologically adjusted ozone levels in the eastern United States: A comparison of two approaches AN - 19518156; 7200099 AB - Assessing the influence of abatement efforts and other human activities on ozone levels is complicated by the atmospheres changeable nature. Two statistical methods, the dynamic linear model (DLM) and the generalized additive model (GAM), are used to estimate ozone trends in the eastern United States and to adjust for meteorological effects. The techniques and resulting estimates are compared and contrasted for four monitoring locations chosen through principal components analysis to represent regional patterns of ozone concentrations. After adjustment for meteorological influence, overall downward trends are evident at all four locations from 1997 to 2004. The results indicate that the two methods estimates of ozone changes agree well. When such estimates are needed quickly, or when many similar, but separate analyses are required, the ease of implementation and relative simplicity of the GAMs are attractive. The DLMs are much more flexible, readily addressing such issues as autocorrelation, the presence of missing values, and estimation of long-term trends or cyclical patterns. Implementation of DLMs, however, is typically more difficult, and especially in the absence of an experienced practitioner, they may be better reserved for in-depth analyses. JF - Atmospheric Environment AU - Zheng, Junyu AU - Swall, Jenise L AU - Cox, William M AU - Davis, Jerry M AD - Atmospheric Modeling Division, National Exposure Research Laboratory, US Environmental Protection Agency, RTP, NC 27711, USA, Jenise.Swall@noaa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 705 EP - 716 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 4 SN - 1352-2310, 1352-2310 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Ozone trends KW - Dynamic linear model KW - Generalized additive model KW - Meteorological adjustment KW - Principal components analysis KW - Carbon monoxide in the atmosphere KW - Pollution monitoring KW - Principal component analysis KW - Mathematical models KW - Statistical analysis KW - USA, East KW - Air quality KW - USA KW - Ozone concentration KW - Meteorology KW - Ozone KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19518156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Interannual+variation+in+meteorologically+adjusted+ozone+levels+in+the+eastern+United+States%3A+A+comparison+of+two+approaches&rft.au=Zheng%2C+Junyu%3BSwall%2C+Jenise+L%3BCox%2C+William+M%3BDavis%2C+Jerry+M&rft.aulast=Zheng&rft.aufirst=Junyu&rft.date=2007-04-01&rft.volume=41&rft.issue=4&rft.spage=705&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2006.09.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-01-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Carbon monoxide in the atmosphere; Principal component analysis; Statistical analysis; Ozone trends; Ozone concentration; Pollution monitoring; Mathematical models; Meteorology; Air quality; Ozone; USA; USA, East DO - http://dx.doi.org/10.1016/j.atmosenv.2006.09.010 ER - TY - JOUR T1 - Numerical study on adjusting and controlling effect of forest cover on PM sub(10) and O sub(3) AN - 19508107; 7200107 AB - A new-coupled air quality numerical modeling system has been developed and applied to the study on the adjusting and controlling effect of forest cover on air quality. The modeling system is composed of Plant Canopy Layer Model (PCLM), Urban Scale Meteorological Model (USMM), and High-Resolution Chemical Model (HRCM). The system was applied to the study on the ecological adjusting and controlling effects on PM sub(10) and O sub(3) in Jinan City, China. The results show that the forest cover can adjust and control PM sub(10) and O sub(3) significantly by reducing the concentrations of PM sub(10) while increasing the concentrations of O sub(3) with the increase of forest cover. JF - Atmospheric Environment AU - Du, Shiyong AU - Kang, Daiwen AU - Lei, Xiaoen AU - Chen, Liren AD - Lanzhou Institute of Chemical Physics of Chinese Academy of Sciences, Lanzhou, Gansu, China, kang.daiwen@epa.gov Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 797 EP - 808 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 4 SN - 1352-2310, 1352-2310 KW - forest cover KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Numerical simulation KW - Forest cover KW - Adjusting and controlling effect KW - PM sub(10) KW - O sub(3) KW - Air quality KW - Mathematical models KW - Atmospheric pollution KW - Atmospheric pollution models KW - Meteorological models KW - Particulate matter in urban air KW - Particulates KW - Numerical models KW - Atmospheric chemistry models KW - Urban atmospheric pollution KW - Ozone concentration KW - Meteorology KW - China, People's Rep. KW - Ozone control KW - Urban areas KW - Ozone KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19508107?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Numerical+study+on+adjusting+and+controlling+effect+of+forest+cover+on+PM+sub%2810%29+and+O+sub%283%29&rft.au=Du%2C+Shiyong%3BKang%2C+Daiwen%3BLei%2C+Xiaoen%3BChen%2C+Liren&rft.aulast=Du&rft.aufirst=Shiyong&rft.date=2007-04-01&rft.volume=41&rft.issue=4&rft.spage=797&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2006.08.055 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-01-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Numerical models; Atmospheric pollution models; Atmospheric pollution; Meteorological models; Atmospheric chemistry models; Ozone concentration; Urban atmospheric pollution; Air quality; Particulate matter in urban air; Ozone control; Ozone; Mathematical models; Meteorology; Particulates; Urban areas; China, People's Rep. DO - http://dx.doi.org/10.1016/j.atmosenv.2006.08.055 ER - TY - JOUR T1 - Development of an index of biotic integrity for a southeastern coastal plain watershed, USA AN - 19338836; 7360713 AB - This study evaluated biological integrity expectations of fish assemblages in wadeable streams for the Alabama portion of the Choctawhatchee River watershed using a multimetric approach. Thirty-four randomly selected stream sites were sampled in late spring 2001 to calibrate an index of biotic integrity (IBI). Validation data were collected during the spring 2001, and summer and fall of 2003 from disturbed and least-impacted targeted sites (n = 20). Thirty-five candidate metrics were evaluated for their responsiveness to environmental degradation. Twelve metrics were selected to evaluate wadeable streams and four replacement metrics were selected for headwater streams. Scores that ranged from 58 to 60 were considered to be representative of excellent biotic integrity (none found in this study), scores of 48-52 as good integrity (31% of the sites in this study), 40-44 as fair (43%), 28-34 as poor (21%), and 12-22 as very poor (5%). Of the four stream condition categories (urban, cattle, row crop, and least impacted), the IBI scores for urban and cattle sites differed significantly from least-impacted sites. Row crop sites, although not significantly different from least-impacted, tended to have greater variability than the other categories. Lower IBI scores at both urban and cattle sites suggest that the IBI accurately reflects stream impairment in the Choctawhatchee River drainage. JF - Journal of the American Water Resources Association AU - Morris, C C AU - Stewart, P M AU - Simon, T P AD - Indiana Department of Environmental Management, Office of Water Quality, Assessment Branch, Biological Studies Section, Indianapolis, Indiana 46206, USA, cmorris@dem.state.in.us Y1 - 2007/04// PY - 2007 DA - Apr 2007 SP - 295 EP - 307 VL - 43 IS - 2 SN - 1093-474X, 1093-474X KW - Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Environmental degradation KW - Variability KW - ASW, USA, Alabama KW - Springs KW - Coastal Plains KW - USA, Alabama, Choctawhatchee R. KW - Freshwater KW - Watersheds KW - Freshwater fish KW - Streams KW - Crops KW - Water springs KW - plains KW - Headwaters KW - Rivers KW - Biological surveys KW - Land use KW - Ecosystem disturbance KW - Cattle KW - Community composition KW - Species diversity KW - summer KW - SW 2060:Effects on water of human nonwater activities KW - Q1 08381:General KW - P 1000:MARINE POLLUTION KW - AQ 00008:Effects of Pollution KW - Q5 08521:Mechanical and natural changes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19338836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Development+of+an+index+of+biotic+integrity+for+a+southeastern+coastal+plain+watershed%2C+USA&rft.au=Morris%2C+C+C%3BStewart%2C+P+M%3BSimon%2C+T+P&rft.aulast=Morris&rft.aufirst=C&rft.date=2007-04-01&rft.volume=43&rft.issue=2&rft.spage=295&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2007.00023.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-05-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Biological surveys; Rivers; Community composition; Species diversity; Freshwater fish; Watersheds; Ecosystem disturbance; Land use; Environmental degradation; Cattle; Water springs; summer; plains; Streams; Crops; Headwaters; Variability; Coastal Plains; Springs; ASW, USA, Alabama; USA, Alabama, Choctawhatchee R.; Freshwater DO - http://dx.doi.org/10.1111/j.1752-1688.2007.00023.x ER - TY - JOUR T1 - Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis AN - 199120776; 17398308 AB - Epidemiological and clinical evidence suggests that an increased intake of long-chain n-3 fatty acids protects against mortality from coronary artery disease. We aimed to test the hypothesis that long-term use of eicosapentaenoic acid (EPA) is effective for prevention of major coronary events in hypercholesterolaemic patients in Japan who consume a large amount of fish. 18 645 patients with a total cholesterol of 6.5 mmol/L or greater were recruited from local physicians throughout Japan between 1996 and 1999. Patients were randomly assigned to receive either 1800 mg of EPA daily with statin (EPA group; n=9326) or statin only (controls; n=9319) with a 5-year follow-up. The primary endpoint was any major coronary event, including sudden cardiac death, fatal and non-fatal myocardial infarction, and other non-fatal events including unstable angina pectoris, angioplasty, stenting, or coronary artery bypass grafting. Analysis was by intention-to-treat. The study was registered at clinicaltrials.gov, number NCT00231738. At mean follow-up of 4.6 years, we detected the primary endpoint in 262 (2.8%) patients in the EPA group and 324 (3.5%) in controls-a 19% relative reduction in major coronary events (p=0.011). Post-treatment LDL cholesterol concentrations decreased 25%, from 4.7 mmol/L in both groups. Serum LDL cholesterol was not a significant factor in a reduction of risk for major coronary events. Unstable angina and non-fatal coronary events were also significantly reduced in the EPA group. Sudden cardiac death and coronary death did not differ between groups. In patients with a history of coronary artery disease who were given EPA treatment, major coronary events were reduced by 19% (secondary prevention subgroup: 158 [8.7%] in the EPA group vs 197 [10.7%] in the control group; p=0.048). In patients with no history of coronary artery disease, EPA treatment reduced major coronary events by 18%, but this finding was not significant (104 [1.4%] in the EPA group vs 127 [1.7%] in the control group; p=0.132). EPA is a promising treatment for prevention of major coronary events, and especially non-fatal coronary events, in Japanese hypercholesterolaemic patients. JF - The Lancet AU - Yokoyama, Mitsuhiro AU - Origasa, Hideki AU - Matsuzaki, Masunori AU - Matsuzawa, Yuji AU - et al Y1 - 2007///Mar 31-Apr 6, PY - 2007 DA - Mar 31-Apr 6, 2007 SP - 1090 EP - 8 CY - London PB - Elsevier Limited VL - 369 IS - 9567 SN - 01406736 KW - Medical Sciences KW - Eicosapentaenoic Acid KW - Angina pectoris KW - Fatty acids KW - Mortality KW - Heart attacks KW - Cholesterol KW - Clinical trials KW - Epidemiology KW - Coronary Disease -- etiology KW - Coronary Disease -- mortality KW - Hypercholesterolemia -- complications KW - Humans KW - Adult KW - Aged KW - Middle Aged KW - Diet KW - Male KW - Japan KW - Female KW - Coronary Disease -- prevention & control KW - Eicosapentaenoic Acid -- therapeutic use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/199120776?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthcompleteshell&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Lancet&rft.atitle=Effects+of+eicosapentaenoic+acid+on+major+coronary+events+in+hypercholesterolaemic+patients+%28JELIS%29%3A+a+randomised+open-label%2C+blinded+endpoint+analysis&rft.au=Yokoyama%2C+Mitsuhiro%3BOrigasa%2C+Hideki%3BMatsuzaki%2C+Masunori%3BMatsuzawa%2C+Yuji%3Bet+al&rft.aulast=Yokoyama&rft.aufirst=Mitsuhiro&rft.date=2007-03-31&rft.volume=369&rft.issue=9567&rft.spage=1090&rft.isbn=&rft.btitle=&rft.title=The+Lancet&rft.issn=01406736&rft_id=info:doi/ LA - English DB - ProQuest Central N1 - Name - Environmental Protection Agency--EPA N1 - Copyright - Copyright Elsevier Limited Mar 31-Apr 6, 2007 N1 - Document feature - Tables; Graphs; Diagrams; References N1 - Last updated - 2015-02-07 N1 - CODEN - LANCAO ER - TY - CPAPER T1 - Novel Metallic and Bimetallic Crosslinked Poly (Vinyl Alcohol) Nanocomposites Prepared under Microwave Irradiation T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40588521; 4545605 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Varma, Rajender S AU - Nadagouda, Mallikarjuna N Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Alcohols KW - Irradiation KW - Microwave radiation KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40588521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Novel+Metallic+and+Bimetallic+Crosslinked+Poly+%28Vinyl+Alcohol%29+Nanocomposites+Prepared+under+Microwave+Irradiation&rft.au=Varma%2C+Rajender+S%3BNadagouda%2C+Mallikarjuna+N&rft.aulast=Varma&rft.aufirst=Rajender&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Challenges and Opportunities for New Disinfection Processes from a Regulatory Perspective T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40580511; 4541344 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Regli, Stig Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Disinfection KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40580511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Challenges+and+Opportunities+for+New+Disinfection+Processes+from+a+Regulatory+Perspective&rft.au=Regli%2C+Stig&rft.aulast=Regli&rft.aufirst=Stig&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sustainability and the Role of the Chemist T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40580018; 4540460 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Gonzalez, Michael A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Resource management KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40580018?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Sustainability+and+the+Role+of+the+Chemist&rft.au=Gonzalez%2C+Michael+A&rft.aulast=Gonzalez&rft.aufirst=Michael&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Chlorinated Vs. Chloraminated Drinking Water: Toxicity-Based Identification of Disinfection By-Products using ESI-MS and ESI-MS/MS T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40579983; 4540325 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Richardson, Susan D AU - Crumley, F Gene AU - Plewa, Michael J AU - Wagner, Elizabeth D AU - Mize, Todd AU - Angel, Peggi AU - Orlando, Ron AU - Williamson, Leah AU - Bartlett, Michael G Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Disinfection KW - Byproducts KW - Drinking water KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40579983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Chlorinated+Vs.+Chloraminated+Drinking+Water%3A+Toxicity-Based+Identification+of+Disinfection+By-Products+using+ESI-MS+and+ESI-MS%2FMS&rft.au=Richardson%2C+Susan+D%3BCrumley%2C+F+Gene%3BPlewa%2C+Michael+J%3BWagner%2C+Elizabeth+D%3BMize%2C+Todd%3BAngel%2C+Peggi%3BOrlando%2C+Ron%3BWilliamson%2C+Leah%3BBartlett%2C+Michael+G&rft.aulast=Richardson&rft.aufirst=Susan&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of the Urinary Metabolites of Rats, Mice and Humans After Oral Arsenic Exposure Focusing on Thioarsenicals T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40578734; 4540261 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Conklin, Sean D AU - Adair, Blakely M AU - Creed, Patricia A AU - Creed, John T AU - Hughes, Michael F AU - Thomas, David J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Metabolites KW - Mice KW - Urine KW - Rats KW - Arsenic KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40578734?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Comparison+of+the+Urinary+Metabolites+of+Rats%2C+Mice+and+Humans+After+Oral+Arsenic+Exposure+Focusing+on+Thioarsenicals&rft.au=Conklin%2C+Sean+D%3BAdair%2C+Blakely+M%3BCreed%2C+Patricia+A%3BCreed%2C+John+T%3BHughes%2C+Michael+F%3BThomas%2C+David+J&rft.aulast=Conklin&rft.aufirst=Sean&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Green Chemistry Approach to Preparation of Core (Fe or Cu)-Shell (Noble Metals) Nanocomposites using Aqueous Ascorbic Acid T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40578696; 4544071 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Varma, Rajender S AU - Nadagouda, Mallikarjuna N Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Metals KW - Ascorbic acid KW - Cores KW - Vitamin C KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40578696?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=A+Green+Chemistry+Approach+to+Preparation+of+Core+%28Fe+or+Cu%29-Shell+%28Noble+Metals%29+Nanocomposites+using+Aqueous+Ascorbic+Acid&rft.au=Varma%2C+Rajender+S%3BNadagouda%2C+Mallikarjuna+N&rft.aulast=Varma&rft.aufirst=Rajender&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Determination of Haloacetic Acids and Dalapon via Ion Chromatography and Tandem Mass Spectrometry T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40578400; 4540329 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Zaffiro, Alan AU - Al-Horr, Rida AU - Munch, David J AU - Pepich, Barry Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Mass spectroscopy KW - Chromatography KW - Haloacetic acids KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40578400?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Determination+of+Haloacetic+Acids+and+Dalapon+via+Ion+Chromatography+and+Tandem+Mass+Spectrometry&rft.au=Zaffiro%2C+Alan%3BAl-Horr%2C+Rida%3BMunch%2C+David+J%3BPepich%2C+Barry&rft.aulast=Zaffiro&rft.aufirst=Alan&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Oxidation of Selected Organophosphate Pesticides during Chlorination of Drinking Water T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40578397; 4540319 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Byrne, Christian AU - Kamel, Alaa AU - Vigo, Craig AU - Ferrario, Joseph AU - Stafford, Charles AU - Verdin, Gregory AU - Siegelman, Frederic AU - Knizner, Steve AU - Hetrick, James Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Drinking water KW - Pesticides KW - Chlorination KW - Oxidation KW - Organophosphates KW - Pesticides (organophosphorus) KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40578397?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Oxidation+of+Selected+Organophosphate+Pesticides+during+Chlorination+of+Drinking+Water&rft.au=Byrne%2C+Christian%3BKamel%2C+Alaa%3BVigo%2C+Craig%3BFerrario%2C+Joseph%3BStafford%2C+Charles%3BVerdin%2C+Gregory%3BSiegelman%2C+Frederic%3BKnizner%2C+Steve%3BHetrick%2C+James&rft.aulast=Byrne&rft.aufirst=Christian&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Transformation and Mobilization of Arsenic Adsorbed on Granular Ferric Hydroxide Under Bioreductive Conditions T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40577399; 4540211 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Al-Abed, Souhail R AU - Jegadeesan, Gautham AU - Pinto, Patricio Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Hydroxides KW - Arsenic KW - Transformation KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40577399?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Transformation+and+Mobilization+of+Arsenic+Adsorbed+on+Granular+Ferric+Hydroxide+Under+Bioreductive+Conditions&rft.au=Al-Abed%2C+Souhail+R%3BJegadeesan%2C+Gautham%3BPinto%2C+Patricio&rft.aulast=Al-Abed&rft.aufirst=Souhail&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - EPA's Drinking Water Regulatory Process T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40576142; 4540452 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Kempic, Jeffrey B Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Drinking water KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40576142?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=EPA%27s+Drinking+Water+Regulatory+Process&rft.au=Kempic%2C+Jeffrey+B&rft.aulast=Kempic&rft.aufirst=Jeffrey&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Pharmacokinetic/Pharmacodynamic Modeling of Permethrin in the Rat T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40575202; 4535082 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Tornero-Velez, R AU - Scollon, E J AU - Starr, J AU - Hughes, M F AU - DeVito, M J AU - Dary, C C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Permethrin KW - Pharmacokinetics KW - Pharmacodynamics KW - Pharmacology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40575202?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Pharmacokinetic%2FPharmacodynamic+Modeling+of+Permethrin+in+the+Rat&rft.au=Tornero-Velez%2C+R%3BScollon%2C+E+J%3BStarr%2C+J%3BHughes%2C+M+F%3BDeVito%2C+M+J%3BDary%2C+C+C&rft.aulast=Tornero-Velez&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Exposure Assessment T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40574948; 4535076 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Reiter, L W AU - Trent, C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Public health KW - Environmental health KW - Environmental assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40574948?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Exposure+Assessment&rft.au=Reiter%2C+L+W%3BTrent%2C+C&rft.aulast=Reiter&rft.aufirst=L&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Practical Approaches to Remediation of Polychlorinated Biphenyls in Sediments T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40573477; 4543496 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Fang, Yuanxiang AU - Al-Abed, Souhail R Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Sediments KW - Bioremediation KW - PCB KW - Polychlorinated biphenyls KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40573477?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Practical+Approaches+to+Remediation+of+Polychlorinated+Biphenyls+in+Sediments&rft.au=Fang%2C+Yuanxiang%3BAl-Abed%2C+Souhail+R&rft.aulast=Fang&rft.aufirst=Yuanxiang&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gene Expression Profiling of Xenobiotic Metabolizing Enzymes (XMEs) in the Aging Male Fisher Rat T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40573309; 4535123 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Lee, J S AU - Wolf, D C AU - Allen, J W AU - Ward, W O AU - Corton, C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Aging KW - Xenobiotics KW - Enzymes KW - Gene expression KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40573309?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Gene+Expression+Profiling+of+Xenobiotic+Metabolizing+Enzymes+%28XMEs%29+in+the+Aging+Male+Fisher+Rat&rft.au=Lee%2C+J+S%3BWolf%2C+D+C%3BAllen%2C+J+W%3BWard%2C+W+O%3BCorton%2C+C&rft.aulast=Lee&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Current State of the use of Genomic Information in Risk Assessment T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40572452; 4535057 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Preston, R J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Genomics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40572452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=The+Current+State+of+the+use+of+Genomic+Information+in+Risk+Assessment&rft.au=Preston%2C+R+J&rft.aulast=Preston&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Alkylanilines and Alkylphenols on Estrogen Receptor Binding and Gene Expression in Rainbow Trout and Humans In Vitro Models T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40571734; 4535202 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Tapper, M AU - Denny, J S AU - Sheedy, B R AU - McKim, J M AU - Pregenzer, J F AU - Wilga, P C AU - Johnson, B J AU - Schmieder, P K Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Estrogen receptors KW - Gene expression KW - Alkylphenols KW - Models KW - Sex hormones KW - Oncorhynchus mykiss KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40571734?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Effects+of+Alkylanilines+and+Alkylphenols+on+Estrogen+Receptor+Binding+and+Gene+Expression+in+Rainbow+Trout+and+Humans+In+Vitro+Models&rft.au=Tapper%2C+M%3BDenny%2C+J+S%3BSheedy%2C+B+R%3BMcKim%2C+J+M%3BPregenzer%2C+J+F%3BWilga%2C+P+C%3BJohnson%2C+B+J%3BSchmieder%2C+P+K&rft.aulast=Tapper&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Hybrid CFD-PBPK Model of Chlorine Gas Uptake and Tissue Dosimetry in the Upper Respiratory Tract (URT) OF F344 Rats T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40571389; 4535092 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Jarabek, A M AU - Schroeter, J D AU - Andersen, M E AU - Kimbell, J S Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Respiratory tract KW - Chlorine KW - Hybrids KW - Rats KW - Dosimetry KW - Respiration KW - Metabolism KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40571389?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=A+Hybrid+CFD-PBPK+Model+of+Chlorine+Gas+Uptake+and+Tissue+Dosimetry+in+the+Upper+Respiratory+Tract+%28URT%29+OF+F344+Rats&rft.au=Jarabek%2C+A+M%3BSchroeter%2C+J+D%3BAndersen%2C+M+E%3BKimbell%2C+J+S&rft.aulast=Jarabek&rft.aufirst=A&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Critical Cell-Cycle-Events in Cancer Development T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40571343; 4535090 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Chiu, A O Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Cancer KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40571343?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Critical+Cell-Cycle-Events+in+Cancer+Development&rft.au=Chiu%2C+A+O&rft.aulast=Chiu&rft.aufirst=A&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bayesian Analysis of Parameters for Pharmacokinetic Models T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40570931; 4535081 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Wambaugh, J F AU - Setzer, W AU - Barton, H A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Pharmacokinetics KW - Mathematical models KW - Bayesian analysis KW - Probability theory KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40570931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Bayesian+Analysis+of+Parameters+for+Pharmacokinetic+Models&rft.au=Wambaugh%2C+J+F%3BSetzer%2C+W%3BBarton%2C+H+A&rft.aulast=Wambaugh&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Blood and Brain Concentrations of Bifenthrin Correlates with Decreased Motor Activity Independent of Time of Exposure T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40570890; 4536681 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Scollon, E J AU - Hughes, M F AU - Starr, J M AU - Crofton, K M AU - Wolansky, M J AU - DeVito, M J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Brain KW - Blood KW - Motor activity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40570890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Blood+and+Brain+Concentrations+of+Bifenthrin+Correlates+with+Decreased+Motor+Activity+Independent+of+Time+of+Exposure&rft.au=Scollon%2C+E+J%3BHughes%2C+M+F%3BStarr%2C+J+M%3BCrofton%2C+K+M%3BWolansky%2C+M+J%3BDeVito%2C+M+J&rft.aulast=Scollon&rft.aufirst=E&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative Distribution of Perfluorooctanoic Acid in Male, Female and Pregnant Mice Following Treatment with 8-2 Fluorotelomer Alcohol (FTOH) T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40570838; 4536658 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Henderson, W M AU - Smith, M Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Alcohols KW - Mice KW - Perfluorooctanoic acid KW - Pregnancy KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40570838?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Comparative+Distribution+of+Perfluorooctanoic+Acid+in+Male%2C+Female+and+Pregnant+Mice+Following+Treatment+with+8-2+Fluorotelomer+Alcohol+%28FTOH%29&rft.au=Henderson%2C+W+M%3BSmith%2C+M&rft.aulast=Henderson&rft.aufirst=W&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Site Characterization to Support Conceptual Model Development for Subsurface Radionuclide Transport T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40570784; 4542184 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Ford, Robert G Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Radioisotopes KW - Models KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40570784?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Site+Characterization+to+Support+Conceptual+Model+Development+for+Subsurface+Radionuclide+Transport&rft.au=Ford%2C+Robert+G&rft.aulast=Ford&rft.aufirst=Robert&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Great Lakes Legacy Act Program for Remediation of Contaminated Sediments T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40570765; 4543488 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Vaidya, Ajit Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - North America, Great Lakes KW - Bioremediation KW - Sediment pollution KW - Lakes KW - Pollution control KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40570765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Great+Lakes+Legacy+Act+Program+for+Remediation+of+Contaminated+Sediments&rft.au=Vaidya%2C+Ajit&rft.aulast=Vaidya&rft.aufirst=Ajit&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Contaminant Mass Balance Model Applications in the Great Lakes: Lower Fox River/Green Bay and Lake Michigan T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40569623; 4539740 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Kreis Jr, Russell G AU - DePinto, Joseph V Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - USA, Michigan L., Green Bay KW - North America, Great Lakes KW - USA, Michigan L. KW - USA, Wisconsin, Lower Fox R. KW - Lakes KW - Water pollution KW - Contaminants KW - Rivers KW - Models KW - Estuaries KW - Brackishwater environment KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40569623?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Contaminant+Mass+Balance+Model+Applications+in+the+Great+Lakes%3A+Lower+Fox+River%2FGreen+Bay+and+Lake+Michigan&rft.au=Kreis+Jr%2C+Russell+G%3BDePinto%2C+Joseph+V&rft.aulast=Kreis+Jr&rft.aufirst=Russell&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Ethynylestradiol Exposure during Larval Development of the Amphibian, Xenopus tropicalis T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40569468; 4535210 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Olmstead, A W AU - Bennett, B A AU - Holcombe, G W AU - Kosian, P A AU - Woodis, K K AU - Korte, J J AU - Degitz, S J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Amphibians KW - Larval development KW - Biological development KW - Amphibiotic species KW - Xenopus tropicalis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40569468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Effects+of+Ethynylestradiol+Exposure+during+Larval+Development+of+the+Amphibian%2C+Xenopus+tropicalis&rft.au=Olmstead%2C+A+W%3BBennett%2C+B+A%3BHolcombe%2C+G+W%3BKosian%2C+P+A%3BWoodis%2C+K+K%3BKorte%2C+J+J%3BDegitz%2C+S+J&rft.aulast=Olmstead&rft.aufirst=A&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Progress in Process Intensification: Synthesis of Imines using a Spinning Tube-in-Tube Reactor T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40569405; 4542893 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Ciszewski, James T AU - Gonzalez, Michael A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Spinning KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40569405?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Progress+in+Process+Intensification%3A+Synthesis+of+Imines+using+a+Spinning+Tube-in-Tube+Reactor&rft.au=Ciszewski%2C+James+T%3BGonzalez%2C+Michael+A&rft.aulast=Ciszewski&rft.aufirst=James&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Estrogen Responsive Plasma Protein Biomarkers in Four Fish Species T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40568505; 4535207 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Walker, C C AU - Salinas, K A AU - Harris, P S AU - Benninghoff, A D AU - Springman, K R AU - Ostrach, D J AU - Hemmer, M J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Bioindicators KW - Estrogens KW - Pisces KW - Plasma proteins KW - Biomarkers KW - Sex hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40568505?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Estrogen+Responsive+Plasma+Protein+Biomarkers+in+Four+Fish+Species&rft.au=Walker%2C+C+C%3BSalinas%2C+K+A%3BHarris%2C+P+S%3BBenninghoff%2C+A+D%3BSpringman%2C+K+R%3BOstrach%2C+D+J%3BHemmer%2C+M+J&rft.aulast=Walker&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Reproductive Toxicity of Vinclozolin and Ketoconazole in Fathead Minnow: Adverse Effects and Compensatory Responses. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40568473; 4535203 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Martinovic, D AU - Blake, L S AU - Durhan, E J AU - Greene, K J AU - Kahl, M D AU - Jensen, K M AU - Johnson, R D AU - Makynen, E A AU - Villeneuve, D L AU - Ankley, G T Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Side effects KW - Toxicity KW - Ketoconazole KW - Vinclozolin KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40568473?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Reproductive+Toxicity+of+Vinclozolin+and+Ketoconazole+in+Fathead+Minnow%3A+Adverse+Effects+and+Compensatory+Responses.&rft.au=Martinovic%2C+D%3BBlake%2C+L+S%3BDurhan%2C+E+J%3BGreene%2C+K+J%3BKahl%2C+M+D%3BJensen%2C+K+M%3BJohnson%2C+R+D%3BMakynen%2C+E+A%3BVilleneuve%2C+D+L%3BAnkley%2C+G+T&rft.aulast=Martinovic&rft.aufirst=D&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Trenbolone on Expression of Estrogen-Responsive Plasma Proteins in Adult Sheepshead Minnow (Cyprinodon variegatus) T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40567706; 4535204 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Hemmer, M J AU - Cripe, G M AU - Salinas, K A AU - Hemmer, B L AU - Goodman, L R AU - Walker, C C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Estrogens KW - Trenbolone KW - Plasma proteins KW - Sex hormones KW - Cyprinodon variegatus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40567706?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Effects+of+Trenbolone+on+Expression+of+Estrogen-Responsive+Plasma+Proteins+in+Adult+Sheepshead+Minnow+%28Cyprinodon+variegatus%29&rft.au=Hemmer%2C+M+J%3BCripe%2C+G+M%3BSalinas%2C+K+A%3BHemmer%2C+B+L%3BGoodman%2C+L+R%3BWalker%2C+C+C&rft.aulast=Hemmer&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Disruption of Testosterone Homeostasis as a Mode of Action for the Reproductive Toxicity of Triazole Fungicides in the Male Rat T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40567403; 4536786 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Goetz, A K AU - Ren, H AU - Schmid, J E AU - Blystone, C R AU - Thillainadarajah, I AU - Best, D S AU - Nichols, H P AU - Strader, L F AU - Wolf, D C AU - Narotsky, M G AU - Rockett, J C AU - Dix, D J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Fungicides KW - Triazoles KW - Toxicity testing KW - Testosterone KW - Homeostasis KW - Bioaccumulation KW - Pollution indicators KW - Sex hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40567403?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Disruption+of+Testosterone+Homeostasis+as+a+Mode+of+Action+for+the+Reproductive+Toxicity+of+Triazole+Fungicides+in+the+Male+Rat&rft.au=Goetz%2C+A+K%3BRen%2C+H%3BSchmid%2C+J+E%3BBlystone%2C+C+R%3BThillainadarajah%2C+I%3BBest%2C+D+S%3BNichols%2C+H+P%3BStrader%2C+L+F%3BWolf%2C+D+C%3BNarotsky%2C+M+G%3BRockett%2C+J+C%3BDix%2C+D+J&rft.aulast=Goetz&rft.aufirst=A&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differential Expression of Retinoic Acid Biosynthetic and Metabolism Genes in Livers from Mice Treated with Hepatotumorigenic and Non-Hepatotumorigenic Conazoles T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40566713; 4536757 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Chen, P AU - Padgett, W T AU - Moore, T AU - Hester, S D AU - Thai, S AU - Winnik, W AU - Nesnow, S Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Metabolism KW - Mice KW - Liver KW - Retinoic acid KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40566713?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Differential+Expression+of+Retinoic+Acid+Biosynthetic+and+Metabolism+Genes+in+Livers+from+Mice+Treated+with+Hepatotumorigenic+and+Non-Hepatotumorigenic+Conazoles&rft.au=Chen%2C+P%3BPadgett%2C+W+T%3BMoore%2C+T%3BHester%2C+S+D%3BThai%2C+S%3BWinnik%2C+W%3BNesnow%2C+S&rft.aulast=Chen&rft.aufirst=P&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of the Cytotoxicity of Drinking Water Disinfection Byproducts (DBPs): Trihalomethanes (THMs), Halonitromethanes (HNMs), and Haloacetic Acids (HAAs) in Normal Human Colon Cells T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40565997; 4536633 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Jones, C P AU - Khamdy, A AU - Sawyer, K AU - Vong, S AU - Moyer, M AU - DeAngelo, A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Byproducts KW - Disinfection KW - Chlorination KW - Trihalomethanes KW - Cytotoxicity KW - Drinking water KW - Colon KW - Haloacetic acids KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40565997?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Evaluation+of+the+Cytotoxicity+of+Drinking+Water+Disinfection+Byproducts+%28DBPs%29%3A+Trihalomethanes+%28THMs%29%2C+Halonitromethanes+%28HNMs%29%2C+and+Haloacetic+Acids+%28HAAs%29+in+Normal+Human+Colon+Cells&rft.au=Jones%2C+C+P%3BKhamdy%2C+A%3BSawyer%2C+K%3BVong%2C+S%3BMoyer%2C+M%3BDeAngelo%2C+A&rft.aulast=Jones&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Landscape Dynamics of Bt, Bats, and Insect Resistance in the Winter Garden Region of Texas T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40565984; 4539362 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Purucker, S Thomas AU - Federico, Paula AU - Hallam, Thomas G AU - Kennard, Kimberly AU - McCracken, Gary F Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - USA, Texas KW - Winter KW - Insects KW - Landscape KW - Aquatic insects KW - Pest control KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40565984?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Landscape+Dynamics+of+Bt%2C+Bats%2C+and+Insect+Resistance+in+the+Winter+Garden+Region+of+Texas&rft.au=Purucker%2C+S+Thomas%3BFederico%2C+Paula%3BHallam%2C+Thomas+G%3BKennard%2C+Kimberly%3BMcCracken%2C+Gary+F&rft.aulast=Purucker&rft.aufirst=S&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Silica Carcinogenicity in a Susceptible Mouse Model T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40565696; 4536624 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Gwinn, M R AU - Battelli, L A AU - Wolfarth, M AU - Leonard, S S AU - Sargent, L M AU - Hubbs, A F AU - Kashon, M L AU - Vallyathan, V Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Silica KW - Carcinogenicity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40565696?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Silica+Carcinogenicity+in+a+Susceptible+Mouse+Model&rft.au=Gwinn%2C+M+R%3BBattelli%2C+L+A%3BWolfarth%2C+M%3BLeonard%2C+S+S%3BSargent%2C+L+M%3BHubbs%2C+A+F%3BKashon%2C+M+L%3BVallyathan%2C+V&rft.aulast=Gwinn&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - American Healthy Homes Survey: A National Study of Residential Pesticides Measured from Floor Wipes T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40565535; 4539376 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Stout II, Daniel M AU - Bradham, Karen AU - Highsmith, V Ross AU - Croghan, Carry W AU - Jones, Paul A AU - Friedman, Warren AU - Pinzer, Eugene A AU - Cox, David AU - Dewalt, Gary Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Pesticides KW - Residential areas KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40565535?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=American+Healthy+Homes+Survey%3A+A+National+Study+of+Residential+Pesticides+Measured+from+Floor+Wipes&rft.au=Stout+II%2C+Daniel+M%3BBradham%2C+Karen%3BHighsmith%2C+V+Ross%3BCroghan%2C+Carry+W%3BJones%2C+Paul+A%3BFriedman%2C+Warren%3BPinzer%2C+Eugene+A%3BCox%2C+David%3BDewalt%2C+Gary&rft.aulast=Stout+II&rft.aufirst=Daniel&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Framework for a Spatial Aquatic Model for Pesticide Risk Assessments T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40565420; 4539366 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Corbin, Mark AU - Thurman, Nelson C AU - Thawley, Michelle Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Pesticides KW - Risk assessment KW - Models KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40565420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Framework+for+a+Spatial+Aquatic+Model+for+Pesticide+Risk+Assessments&rft.au=Corbin%2C+Mark%3BThurman%2C+Nelson+C%3BThawley%2C+Michelle&rft.aulast=Corbin&rft.aufirst=Mark&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Riparian Ecosystem Management Model (REMM): Regulatory Interests and Perspective T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40564969; 4539390 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Jones, R David Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Ecosystem management KW - Models KW - Rivers KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40564969?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Riparian+Ecosystem+Management+Model+%28REMM%29%3A+Regulatory+Interests+and+Perspective&rft.au=Jones%2C+R+David&rft.aulast=Jones&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Aging as a Modulator of Chemical Toxicity T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40564481; 4536850 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Corton, C AU - Mehendale, H M Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Aging KW - Toxicity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40564481?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Aging+as+a+Modulator+of+Chemical+Toxicity&rft.au=Corton%2C+C%3BMehendale%2C+H+M&rft.aulast=Corton&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of Geospatial Data in Endangered Species Risk Assessments for Pesticides T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40563877; 4539365 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Corbin, Mark AU - Thurman, Nelson C AU - Thawley, Michelle Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Pesticides KW - Risk assessment KW - Endangered species KW - Rare species KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40563877?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Use+of+Geospatial+Data+in+Endangered+Species+Risk+Assessments+for+Pesticides&rft.au=Corbin%2C+Mark%3BThurman%2C+Nelson+C%3BThawley%2C+Michelle&rft.aulast=Corbin&rft.aufirst=Mark&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Application of Spatial Analysis in Estimating Drinking Water Exposure for the N-Methyl Carbamate Cumulative Risk Assessment T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40563841; 4539364 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Thurman, Nelson C AU - Young, Dirk Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Spatial analysis KW - Drinking water KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40563841?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Application+of+Spatial+Analysis+in+Estimating+Drinking+Water+Exposure+for+the+N-Methyl+Carbamate+Cumulative+Risk+Assessment&rft.au=Thurman%2C+Nelson+C%3BYoung%2C+Dirk&rft.aulast=Thurman&rft.aufirst=Nelson&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Great Lakes Offshore Biological Desert and the Nearshore Slime Around the Tub T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40563605; 4539742 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Rockwell, David C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - North America, Great Lakes KW - Deserts KW - Lakes KW - Slimes KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40563605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Great+Lakes+Offshore+Biological+Desert+and+the+Nearshore+Slime+Around+the+Tub&rft.au=Rockwell%2C+David+C&rft.aulast=Rockwell&rft.aufirst=David&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Multivariable Approaches for Determining Groundwater Vulnerability to Agrochemical Movement in Soil, Part 2: Cluster Analysis of California Statewide Groundwater Vulnerability T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40563543; 4539340 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Troiano, John AU - Spurlock, Frank AU - Marade, Joe AU - Chen, Wenlin Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - USA, California KW - Aquifers KW - Vulnerability KW - Ground water KW - Soil KW - Agrochemicals KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40563543?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Multivariable+Approaches+for+Determining+Groundwater+Vulnerability+to+Agrochemical+Movement+in+Soil%2C+Part+2%3A+Cluster+Analysis+of+California+Statewide+Groundwater+Vulnerability&rft.au=Troiano%2C+John%3BSpurlock%2C+Frank%3BMarade%2C+Joe%3BChen%2C+Wenlin&rft.aulast=Troiano&rft.aufirst=John&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Multivariable Approaches for Determining Groundwater Vulnerability to Agrochemical Movement in Soil, Part 1: Classification and Regression Tree Analysis of California Central Valley T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40562870; 4539339 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Troiano, John AU - Huber, Stefan AU - Spurlock, Frank AU - Marade, Joe AU - Dharmasri, Cecil AU - Phelps, Warner AU - Chen, Wenlin Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - USA, California, Central Valley KW - USA, California KW - Aquifers KW - Soil KW - Vulnerability KW - Ground water KW - Trees KW - Valleys KW - Classification KW - Agrochemicals KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40562870?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Multivariable+Approaches+for+Determining+Groundwater+Vulnerability+to+Agrochemical+Movement+in+Soil%2C+Part+1%3A+Classification+and+Regression+Tree+Analysis+of+California+Central+Valley&rft.au=Troiano%2C+John%3BHuber%2C+Stefan%3BSpurlock%2C+Frank%3BMarade%2C+Joe%3BDharmasri%2C+Cecil%3BPhelps%2C+Warner%3BChen%2C+Wenlin&rft.aulast=Troiano&rft.aufirst=John&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Particulate Matter, Oxidative Stress and Neurodegeneration T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40562660; 4536856 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Veronesi, B AU - Gillepsie, P AU - Chen, L Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Suspended particulate matter KW - Stress KW - Oxidative stress KW - Neurodegeneration KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40562660?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Particulate+Matter%2C+Oxidative+Stress+and+Neurodegeneration&rft.au=Veronesi%2C+B%3BGillepsie%2C+P%3BChen%2C+L&rft.aulast=Veronesi&rft.aufirst=B&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Developmental Immunotoxicology and Risk Assessment T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40562584; 4536583 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Yang, Y G Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40562584?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Developmental+Immunotoxicology+and+Risk+Assessment&rft.au=Yang%2C+Y+G&rft.aulast=Yang&rft.aufirst=Y&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Reducing the Default Uncertainty for Subchronic to Chronic Exposure for the Bromobenzene Reference Dose (RfD) and Reference Concentration (RfC) using data from Chlorobenzene. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40562131; 4536481 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Smallwood, C L Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Bromobenzene KW - Chronic exposure KW - Chlorobenzene KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40562131?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Reducing+the+Default+Uncertainty+for+Subchronic+to+Chronic+Exposure+for+the+Bromobenzene+Reference+Dose+%28RfD%29+and+Reference+Concentration+%28RfC%29+using+data+from+Chlorobenzene.&rft.au=Smallwood%2C+C+L&rft.aulast=Smallwood&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Reference Dose for 1,1,2,2-Tetrachloroethane T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40561752; 4536476 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Donohue, J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40561752?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Reference+Dose+for+1%2C1%2C2%2C2-Tetrachloroethane&rft.au=Donohue%2C+J&rft.aulast=Donohue&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Thyroid Hormone Insufficiency and Brain Development Examining Neurotoxicity at Low Levels of Hormone Disruption. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40561664; 4536445 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Gilbert, M E AU - Taylor, M AU - Sharlin, D AU - Anderson, W AU - Ferguson, D AU - Zoeller, R T Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Hormones KW - Neurotoxicity KW - Brain KW - Thyroid hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40561664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Thyroid+Hormone+Insufficiency+and+Brain+Development+Examining+Neurotoxicity+at+Low+Levels+of+Hormone+Disruption.&rft.au=Gilbert%2C+M+E%3BTaylor%2C+M%3BSharlin%2C+D%3BAnderson%2C+W%3BFerguson%2C+D%3BZoeller%2C+R+T&rft.aulast=Gilbert&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Predicting Biochemical Responses to Endocrine Active Compounds: Mathematical Model of Steroidogenesis in Small Fish Ovaries T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40561451; 4535801 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Breen, M S AU - Villeneuve, D AU - Breen, M AU - Ankley, G AU - Conolly, R Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Mathematical models KW - Pisces KW - Biochemistry KW - Ovaries KW - Steroidogenesis KW - Endocrine active compounds KW - Endocrinology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40561451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Predicting+Biochemical+Responses+to+Endocrine+Active+Compounds%3A+Mathematical+Model+of+Steroidogenesis+in+Small+Fish+Ovaries&rft.au=Breen%2C+M+S%3BVilleneuve%2C+D%3BBreen%2C+M%3BAnkley%2C+G%3BConolly%2C+R&rft.aulast=Breen&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of a Drinking Water Public Health Goal for Cadmium T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40561385; 4536508 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Sedman, R AU - Howd, R A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Public health KW - Drinking water KW - Cadmium KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40561385?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Development+of+a+Drinking+Water+Public+Health+Goal+for+Cadmium&rft.au=Sedman%2C+R%3BHowd%2C+R+A&rft.aulast=Sedman&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling the Toxicokinetics of Inhaled Toluene in Rats: The Impact of Feeding Status, Physical Activity and Strain T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40561072; 4536464 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Kenyon, E M AU - Benignus, V AU - Eklund, C AU - Bushnell, P Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Physical activity KW - Feeding KW - Toluene KW - Rats KW - Strains KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40561072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Modeling+the+Toxicokinetics+of+Inhaled+Toluene+in+Rats%3A+The+Impact+of+Feeding+Status%2C+Physical+Activity+and+Strain&rft.au=Kenyon%2C+E+M%3BBenignus%2C+V%3BEklund%2C+C%3BBushnell%2C+P&rft.aulast=Kenyon&rft.aufirst=E&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identification of Common Genes and Pathways Regulated by PPARalpha Activators T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560892; 4535447 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Lloyd, S AU - Vallanat, B AU - Rosen, M AU - Abbott, B D AU - Das, K P AU - Zehr, R D AU - Lau, C AU - Corton, C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Carcinogenesis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Identification+of+Common+Genes+and+Pathways+Regulated+by+PPARalpha+Activators&rft.au=Lloyd%2C+S%3BVallanat%2C+B%3BRosen%2C+M%3BAbbott%2C+B+D%3BDas%2C+K+P%3BZehr%2C+R+D%3BLau%2C+C%3BCorton%2C+C&rft.aulast=Lloyd&rft.aufirst=S&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Express: The EXAMS/PRZM Exposure Simulation Shell T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40560637; 4539391 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Burns, Lawrence Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Simulation KW - Shells KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560637?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Express%3A+The+EXAMS%2FPRZM+Exposure+Simulation+Shell&rft.au=Burns%2C+Lawrence&rft.aulast=Burns&rft.aufirst=Lawrence&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Potential for Human Exposures to Pet-Borne Diazinon Residues Following Residential Lawn Applications T2 - 233rd National Meeting and Exposition of the American Chemical Society AN - 40560556; 4539378 JF - 233rd National Meeting and Exposition of the American Chemical Society AU - Morgan, Marsha K AU - Stout II, Daniel M AU - Egeghy, Peter P Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Residues KW - Diazinon KW - Pesticides KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560556?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Potential+for+Human+Exposures+to+Pet-Borne+Diazinon+Residues+Following+Residential+Lawn+Applications&rft.au=Morgan%2C+Marsha+K%3BStout+II%2C+Daniel+M%3BEgeghy%2C+Peter+P&rft.aulast=Morgan&rft.aufirst=Marsha&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=233rd+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys.acs.org/acs/233nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Retrospective Analysis of 12 Human Studies with Pesticides (1992 to 2001) to Assess RBC AChE Activity and Clinical Signs T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560532; 4536239 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Doherty, J AU - Reaves, E AU - Taylor, L AU - Scarano, L Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Pesticides KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560532?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=A+Retrospective+Analysis+of+12+Human+Studies+with+Pesticides+%281992+to+2001%29+to+Assess+RBC+AChE+Activity+and+Clinical+Signs&rft.au=Doherty%2C+J%3BReaves%2C+E%3BTaylor%2C+L%3BScarano%2C+L&rft.aulast=Doherty&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of Observed and Predicted Blood Lead Levels Following Lead Paint Abatement T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560521; 4536507 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Wichers, L B AU - Diamond, G L AU - Brown, J S Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Lead KW - Paints KW - Blood KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Comparison+of+Observed+and+Predicted+Blood+Lead+Levels+Following+Lead+Paint+Abatement&rft.au=Wichers%2C+L+B%3BDiamond%2C+G+L%3BBrown%2C+J+S&rft.aulast=Wichers&rft.aufirst=L&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of Short-Term, Subchronic and Chronic Oral Reference Doses (RfDs) for Microcystin-LR T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560496; 4536493 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Hawkins, B AU - Carlson-Lynch, H AU - Odin, M Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Microcystin-LR KW - Biological poisons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560496?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Development+of+Short-Term%2C+Subchronic+and+Chronic+Oral+Reference+Doses+%28RfDs%29+for+Microcystin-LR&rft.au=Hawkins%2C+B%3BCarlson-Lynch%2C+H%3BOdin%2C+M&rft.aulast=Hawkins&rft.aufirst=B&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cardiovascular Mortality and Lung Cancer Risk from Diesel Exhaust Particulate in California T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560489; 4536219 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Marty, M A AU - Salmon, A G AU - Alexeeff, G V Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - USA, California KW - Particulates KW - Lung cancer KW - Mortality KW - Exhaust emissions KW - Diesel KW - Cardiovascular diseases KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Cardiovascular+Mortality+and+Lung+Cancer+Risk+from+Diesel+Exhaust+Particulate+in+California&rft.au=Marty%2C+M+A%3BSalmon%2C+A+G%3BAlexeeff%2C+G+V&rft.aulast=Marty&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Physiologically Based Pharmacokinetic (PBPK) Modeling in the Elderly T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560418; 4536466 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Thompson, C AU - Sonawane, B AU - Krishnan, K Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Elderly KW - Pharmacokinetics KW - Geriatrics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560418?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Physiologically+Based+Pharmacokinetic+%28PBPK%29+Modeling+in+the+Elderly&rft.au=Thompson%2C+C%3BSonawane%2C+B%3BKrishnan%2C+K&rft.aulast=Thompson&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Behavioral Assessments of Long-Evans Rats Following a 13-Week Subchronic Toluene Exposure. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560206; 4536160 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Samsam, T E AU - Oshiro, W M AU - Gilbert, M E AU - Bushnell, P J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Toluene KW - Rats KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Behavioral+Assessments+of+Long-Evans+Rats+Following+a+13-Week+Subchronic+Toluene+Exposure.&rft.au=Samsam%2C+T+E%3BOshiro%2C+W+M%3BGilbert%2C+M+E%3BBushnell%2C+P+J&rft.aulast=Samsam&rft.aufirst=T&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Risk Assessment for Sites with Volatile Contaminants in Shallow Groundwater T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560110; 4536225 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Wong-Yim, P AU - Taras, T L AU - Davis, B K AU - Wade1, M. J. Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Aquifers KW - Groundwater pollution KW - Contaminants KW - Volatiles KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560110?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Risk+Assessment+for+Sites+with+Volatile+Contaminants+in+Shallow+Groundwater&rft.au=Wong-Yim%2C+P%3BTaras%2C+T+L%3BDavis%2C+B+K%3BWade1%2C+M.+J.&rft.aulast=Wong-Yim&rft.aufirst=P&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Application of Mode of Action and Dose-Response Information in a Chemical Mixtures Risk Assessment T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560093; 4535384 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Lipscomb, J C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Dose-response effects KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560093?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Application+of+Mode+of+Action+and+Dose-Response+Information+in+a+Chemical+Mixtures+Risk+Assessment&rft.au=Lipscomb%2C+J+C&rft.aulast=Lipscomb&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Epigenetic Processes as Key Events in the Mode of Action for Tumor Formation T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40560044; 4535381 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Preston, R J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Tumors KW - Epigenetics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40560044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Epigenetic+Processes+as+Key+Events+in+the+Mode+of+Action+for+Tumor+Formation&rft.au=Preston%2C+R+J&rft.aulast=Preston&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Nicotinic-Receptor Blockade and the Effects of Anatoxin-A on the Motor Activity of Rats: Comparison with Nicotine. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559820; 4536169 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Jarema, K A AU - Farmer, J D AU - MacPhail, R C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Nicotine KW - Rats KW - Motor activity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Nicotinic-Receptor+Blockade+and+the+Effects+of+Anatoxin-A+on+the+Motor+Activity+of+Rats%3A+Comparison+with+Nicotine.&rft.au=Jarema%2C+K+A%3BFarmer%2C+J+D%3BMacPhail%2C+R+C&rft.aulast=Jarema&rft.aufirst=K&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Novel Technique for Quantitative Estimation of Uptake of Diesel Exhaust Particles by Lung Cells T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559802; 4535338 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Saxena, R K AU - Hays, M D AU - Gilmour, I Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Particulates KW - Lung KW - Exhaust emissions KW - Diesel KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559802?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=A+Novel+Technique+for+Quantitative+Estimation+of+Uptake+of+Diesel+Exhaust+Particles+by+Lung+Cells&rft.au=Saxena%2C+R+K%3BHays%2C+M+D%3BGilmour%2C+I&rft.aulast=Saxena&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Subchronic Toxicity of Inhaled Toluene in Rats: Immunology, Cardiac Gene Expression, and Markers of Oxidative Stress. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559768; 4536162 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Bushnell, P J AU - Evansky, P A AU - Kodavanti, U P AU - Luebke, R W AU - Copeland, C B AU - DeWitt, J C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Stress KW - Immunology KW - Toluene KW - Rats KW - Oxidative stress KW - Gene expression KW - Toxicity KW - Heart KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559768?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Subchronic+Toxicity+of+Inhaled+Toluene+in+Rats%3A+Immunology%2C+Cardiac+Gene+Expression%2C+and+Markers+of+Oxidative+Stress.&rft.au=Bushnell%2C+P+J%3BEvansky%2C+P+A%3BKodavanti%2C+U+P%3BLuebke%2C+R+W%3BCopeland%2C+C+B%3BDeWitt%2C+J+C&rft.aulast=Bushnell&rft.aufirst=P&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling the Interaction Threshold: The Break-Point between Additivity and Non-Additivity T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559735; 4536329 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - El-Masri, H A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Chemical interactions KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559735?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Modeling+the+Interaction+Threshold%3A+The+Break-Point+between+Additivity+and+Non-Additivity&rft.au=El-Masri%2C+H+A&rft.aulast=El-Masri&rft.aufirst=H&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Diesel Particle Instillation Enhances Inflammatory and Neurotrophin Responses in the Lungs of Allergic BALB/C Mice T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559720; 4535590 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Farraj, A K AU - Haykal-Coates, N AU - Sutherland, B J AU - Gavett, S H Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Particulates KW - Lung KW - Mice KW - Diesel KW - Inflammation KW - Neurotrophins KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Diesel+Particle+Instillation+Enhances+Inflammatory+and+Neurotrophin+Responses+in+the+Lungs+of+Allergic+BALB%2FC+Mice&rft.au=Farraj%2C+A+K%3BHaykal-Coates%2C+N%3BSutherland%2C+B+J%3BGavett%2C+S+H&rft.aulast=Farraj&rft.aufirst=A&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Issues and Approaches for Setting Health-based Exposure Limits for Irritants T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559664; 4536313 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Alexeeff, G V AU - Broadwin, R AU - Salmon, A G Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Respiratory tract KW - Irritation KW - Respiration KW - Metabolism KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Issues+and+Approaches+for+Setting+Health-based+Exposure+Limits+for+Irritants&rft.au=Alexeeff%2C+G+V%3BBroadwin%2C+R%3BSalmon%2C+A+G&rft.aulast=Alexeeff&rft.aufirst=G&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling Volatile Organic Compound Pharmacokinetics in Rat Pups T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559588; 4536031 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Barton, H A AU - Rodriguez, C E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Volatile organic compounds KW - Pharmacokinetics KW - Pups KW - Organic compounds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559588?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Modeling+Volatile+Organic+Compound+Pharmacokinetics+in+Rat+Pups&rft.au=Barton%2C+H+A%3BRodriguez%2C+C+E&rft.aulast=Barton&rft.aufirst=H&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Physiological Parameters in Healthy and Diseased Elderly T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559489; 4536203 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Sonawane, B R AU - Thompson, C AU - Hattis, D AU - Tardiff, R AU - Krishan, K Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Elderly KW - Physiology KW - Geriatrics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Physiological+Parameters+in+Healthy+and+Diseased+Elderly&rft.au=Sonawane%2C+B+R%3BThompson%2C+C%3BHattis%2C+D%3BTardiff%2C+R%3BKrishan%2C+K&rft.aulast=Sonawane&rft.aufirst=B&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Activation of Mouse and Human Peroxisome Proliferator-Activated Receptor Alpha (PPARa) by Perfluoroalkyl Acids (PFAAs) Investigated using a Trans-Activation Model in Cos-1 Cells T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40559455; 4536194 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Takacs, M AU - Abbott, B D Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Peroxisome proliferator-activated receptors KW - Acids KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40559455?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Activation+of+Mouse+and+Human+Peroxisome+Proliferator-Activated+Receptor+Alpha+%28PPARa%29+by+Perfluoroalkyl+Acids+%28PFAAs%29+Investigated+using+a+Trans-Activation+Model+in+Cos-1+Cells&rft.au=Takacs%2C+M%3BAbbott%2C+B+D&rft.aulast=Takacs&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of the H295R Cell to Evaluate the Effect of Environmental Compounds on Steroid Hormone Production T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558863; 4534902 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Buckalew, A R AU - Laskey, J W AU - Goldman, J M AU - Higley, E B AU - Giesy, J P AU - Hecker, M AU - Cooper, R L Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Steroid hormones KW - Environmental factors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558863?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Use+of+the+H295R+Cell+to+Evaluate+the+Effect+of+Environmental+Compounds+on+Steroid+Hormone+Production&rft.au=Buckalew%2C+A+R%3BLaskey%2C+J+W%3BGoldman%2C+J+M%3BHigley%2C+E+B%3BGiesy%2C+J+P%3BHecker%2C+M%3BCooper%2C+R+L&rft.aulast=Buckalew&rft.aufirst=A&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Lack of Alterations in Thyroid Hormones Following a Single Postnatal Exposure to Polybrominated Diphenyl Ether 47 T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558840; 4535570 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Gee, J R AU - Hedge, J M AU - Phillips, P M AU - McDaniel, K L AU - Moser, V C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Polybrominated diphenyl ethers KW - Hormones KW - Thyroid hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Lack+of+Alterations+in+Thyroid+Hormones+Following+a+Single+Postnatal+Exposure+to+Polybrominated+Diphenyl+Ether+47&rft.au=Gee%2C+J+R%3BHedge%2C+J+M%3BPhillips%2C+P+M%3BMcDaniel%2C+K+L%3BMoser%2C+V+C&rft.aulast=Gee&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling a Mixture: PBPK/PD Approaches for Predicting Chemical Interactions T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558822; 4536324 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Moser, V C AU - Krishnan, K Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Chemical interactions KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558822?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Modeling+a+Mixture%3A+PBPK%2FPD+Approaches+for+Predicting+Chemical+Interactions&rft.au=Moser%2C+V+C%3BKrishnan%2C+K&rft.aulast=Moser&rft.aufirst=V&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cumulative Reproductive Effects of in Utero Administration of Mixtures of Antiandrogens in Male SD Rats: Synergy or Additivity? T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558637; 4536561 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Gray, L E AU - Furr, J AU - Wilson, V S AU - Hotchkiss, A K AU - Howdeshell, K AU - Rider, C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Rats KW - Antiandrogens KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558637?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Cumulative+Reproductive+Effects+of+in+Utero+Administration+of+Mixtures+of+Antiandrogens+in+Male+SD+Rats%3A+Synergy+or+Additivity%3F&rft.au=Gray%2C+L+E%3BFurr%2C+J%3BWilson%2C+V+S%3BHotchkiss%2C+A+K%3BHowdeshell%2C+K%3BRider%2C+C&rft.aulast=Gray&rft.aufirst=L&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of an In Vitro Pre-Screening Strategy to Prioritize Environmental Chemicals for Further Testing: Androgen and Estrogen Receptor Mediated Activity. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558534; 4534909 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Wilson, V S AU - Schmid, J E AU - Blakeman, D P AU - Pregenzer, J F AU - McKim, J M AU - Goldman, J M AU - Gray, L E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Estrogen receptors KW - Androgens KW - Sex hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558534?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Evaluation+of+an+In+Vitro+Pre-Screening+Strategy+to+Prioritize+Environmental+Chemicals+for+Further+Testing%3A+Androgen+and+Estrogen+Receptor+Mediated+Activity.&rft.au=Wilson%2C+V+S%3BSchmid%2C+J+E%3BBlakeman%2C+D+P%3BPregenzer%2C+J+F%3BMcKim%2C+J+M%3BGoldman%2C+J+M%3BGray%2C+L+E&rft.aulast=Wilson&rft.aufirst=V&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - b Subunits Increase Sensitivity of Sodium Channel Na @@dV@1.3, but not Na @@dV@1.2, to Type II Pyrethroids T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558527; 4535533 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Shafer, T J AU - Meacham, C A AU - Watkins, J A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Sodium channels KW - Channels KW - Pyrethroids KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558527?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=b+Subunits+Increase+Sensitivity+of+Sodium+Channel+Na+%40%40dV%401.3%2C+but+not+Na+%40%40dV%401.2%2C+to+Type+II+Pyrethroids&rft.au=Shafer%2C+T+J%3BMeacham%2C+C+A%3BWatkins%2C+J+A&rft.aulast=Shafer&rft.aufirst=T&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Pet Cats in the U.S. Have High Polybrominated Diphenyl Ether (PBDE) Serum Levels. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558442; 4535578 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Dye, J AU - Venier, M AU - Ward, C R AU - Hites, R A AU - Birnbaum, L S Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - USA KW - Polybrominated diphenyl ethers KW - Serum levels KW - Brominated hydrocarbons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558442?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Pet+Cats+in+the+U.S.+Have+High+Polybrominated+Diphenyl+Ether+%28PBDE%29+Serum+Levels.&rft.au=Dye%2C+J%3BVenier%2C+M%3BWard%2C+C+R%3BHites%2C+R+A%3BBirnbaum%2C+L+S&rft.aulast=Dye&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Incorporating Immunology into Ecological Risk Assessment T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40558050; 4536026 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Nacci, D Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Immunology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40558050?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Incorporating+Immunology+into+Ecological+Risk+Assessment&rft.au=Nacci%2C+D&rft.aulast=Nacci&rft.aufirst=D&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Structure Activity Relationship of Phthalate Esters to Inhibited Fetal Testicular Testosterone Production in the Sprague Dawley Rat T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557877; 4536560 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Howdeshell, K L AU - Furr, J AU - Lambright, C R AU - Wilson, V S AU - Gray, L Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Phthalates KW - Esters KW - Testosterone KW - Fetuses KW - Testes KW - Phthalate esters KW - Sex hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557877?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Structure+Activity+Relationship+of+Phthalate+Esters+to+Inhibited+Fetal+Testicular+Testosterone+Production+in+the+Sprague+Dawley+Rat&rft.au=Howdeshell%2C+K+L%3BFurr%2C+J%3BLambright%2C+C+R%3BWilson%2C+V+S%3BGray%2C+L&rft.aulast=Howdeshell&rft.aufirst=K&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Perfluorobutyrate Exposure in Mice during Pregnancy. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557646; 4536259 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Das, K P AU - Grey, B AU - Butenhoff, J AU - Tanaka, S AU - Ehresman, D AU - Zehr, D AU - Lau, C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Pregnancy KW - Mice KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557646?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Effects+of+Perfluorobutyrate+Exposure+in+Mice+during+Pregnancy.&rft.au=Das%2C+K+P%3BGrey%2C+B%3BButenhoff%2C+J%3BTanaka%2C+S%3BEhresman%2C+D%3BZehr%2C+D%3BLau%2C+C&rft.aulast=Das&rft.aufirst=K&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of a Human Physiologically-Based Pharmacokinetic (PBPK) Model for Inorganic Arsenic and its Mono- And Di-methylated Metabolites T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557553; 4536450 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - El-Masri, H AU - Kenyon, E M Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Metabolites KW - Pharmacokinetics KW - Arsenic KW - Models KW - Human physiology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557553?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Development+of+a+Human+Physiologically-Based+Pharmacokinetic+%28PBPK%29+Model+for+Inorganic+Arsenic+and+its+Mono-+And+Di-methylated+Metabolites&rft.au=El-Masri%2C+H%3BKenyon%2C+E+M&rft.aulast=El-Masri&rft.aufirst=H&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Acute Dimethydithiocarbamate (DMDC) Exposure Alters Neuroendocrine Control of Ovulation (OV) but Continued Dosing does Not. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557545; 4534922 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Cooper, R L AU - Buckalew, A AU - Ferrell, J AU - Stoker, T Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Ovulation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557545?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Acute+Dimethydithiocarbamate+%28DMDC%29+Exposure+Alters+Neuroendocrine+Control+of+Ovulation+%28OV%29+but+Continued+Dosing+does+Not.&rft.au=Cooper%2C+R+L%3BBuckalew%2C+A%3BFerrell%2C+J%3BStoker%2C+T&rft.aulast=Cooper&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Brominated Flame Retardant Mixture, DE-71, Affects Mammary Tissue of Rat Offspring Following Developmental Exposure T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557470; 4535293 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Coburn, C AU - Rayner, J L AU - Kodavanti, P AU - Fenton, S E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Offspring KW - Fire retardant chemicals KW - Progeny KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557470?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=A+Brominated+Flame+Retardant+Mixture%2C+DE-71%2C+Affects+Mammary+Tissue+of+Rat+Offspring+Following+Developmental+Exposure&rft.au=Coburn%2C+C%3BRayner%2C+J+L%3BKodavanti%2C+P%3BFenton%2C+S+E&rft.aulast=Coburn&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Alternative Approaches for Noncancer Risk Assessment of Phosgene T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557372; 4536216 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Singh, D V AU - Gift, J AU - McGaughy, R AU - Sonawane, B Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Phosgene KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557372?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Alternative+Approaches+for+Noncancer+Risk+Assessment+of+Phosgene&rft.au=Singh%2C+D+V%3BGift%2C+J%3BMcGaughy%2C+R%3BSonawane%2C+B&rft.aulast=Singh&rft.aufirst=D&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Child-Specific Reference Values for School Site Risk Assessment are Based on Pharmacodynamic and Pharmacokinetic Differences between Children and Adults T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557325; 4535465 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Knadle, S A AU - Chan, D W AU - Qiao, D AU - Camacho, S A AU - Siegel, D M Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Children KW - Pharmacokinetics KW - Schools KW - Pharmacodynamics KW - Pharmacology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557325?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Child-Specific+Reference+Values+for+School+Site+Risk+Assessment+are+Based+on+Pharmacodynamic+and+Pharmacokinetic+Differences+between+Children+and+Adults&rft.au=Knadle%2C+S+A%3BChan%2C+D+W%3BQiao%2C+D%3BCamacho%2C+S+A%3BSiegel%2C+D+M&rft.aulast=Knadle&rft.aufirst=S&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Computational Modeling to Evaluate Candidate Modes of Action for the Carcinogenicity of Arsenic T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557258; 4535716 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Conolly, R AU - Breen, M AU - Zhao, M Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Carcinogenicity KW - Arsenic KW - Computer applications KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557258?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Computational+Modeling+to+Evaluate+Candidate+Modes+of+Action+for+the+Carcinogenicity+of+Arsenic&rft.au=Conolly%2C+R%3BBreen%2C+M%3BZhao%2C+M&rft.aulast=Conolly&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of Gene Expression Markers of Compensatory and Direct Effects of TPO and NIS Inhibition in the Amphibian Thyroid Gland. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40557051; 4535213 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Korte, J J AU - Hornung, M W AU - Holcombe, G W AU - Tietge, J E AU - Degitz, S J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Thyroid KW - Amphibians KW - Gene expression KW - Biological development KW - Amphibiotic species KW - Glands KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40557051?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Development+of+Gene+Expression+Markers+of+Compensatory+and+Direct+Effects+of+TPO+and+NIS+Inhibition+in+the+Amphibian+Thyroid+Gland.&rft.au=Korte%2C+J+J%3BHornung%2C+M+W%3BHolcombe%2C+G+W%3BTietge%2C+J+E%3BDegitz%2C+S+J&rft.aulast=Korte&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Approaches to Assessing Whether a Carcinogen is Acting Via a Genotoxic Mode of Action T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556980; 4536294 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Hsu, C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Genotoxicity KW - Carcinogens KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556980?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Approaches+to+Assessing+Whether+a+Carcinogen+is+Acting+Via+a+Genotoxic+Mode+of+Action&rft.au=Hsu%2C+C&rft.aulast=Hsu&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Human Health Risk Assessment Tools: Supporting the Risk Assessment Process at the National Homeland Security Research Center T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556829; 4535792 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Moudgal, C AU - Garrahan, K AU - Sonich-Mullin, C AU - Brady-Roberts, E AU - Gavrelis, N AU - Arbogast, M AU - Dunn, S AU - Collie, S AU - Smith, J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Security KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556829?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Human+Health+Risk+Assessment+Tools%3A+Supporting+the+Risk+Assessment+Process+at+the+National+Homeland+Security+Research+Center&rft.au=Moudgal%2C+C%3BGarrahan%2C+K%3BSonich-Mullin%2C+C%3BBrady-Roberts%2C+E%3BGavrelis%2C+N%3BArbogast%2C+M%3BDunn%2C+S%3BCollie%2C+S%3BSmith%2C+J&rft.aulast=Moudgal&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Age-Related Effects of Toluene on the Motor Activity of Brown Norway Rats. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556575; 4536163 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - MacPhail, R C AU - Farmer, J D AU - Jarema, K A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Norway KW - Toluene KW - Rats KW - Motor activity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Age-Related+Effects+of+Toluene+on+the+Motor+Activity+of+Brown+Norway+Rats.&rft.au=MacPhail%2C+R+C%3BFarmer%2C+J+D%3BJarema%2C+K+A&rft.aulast=MacPhail&rft.aufirst=R&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of Urinary Bladder Pathology in Male and Female C3H Mice Exposed to Sodium Arsenite from Gestation through Young Adulthood T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556446; 4535453 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Ahlborn, G AU - Grindstaff, R AU - Allen, J AU - Nelson, G AU - Kitchin, K AU - Preston, J AU - Waalkes, M AU - Diwan, B AU - Delker, D Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Sodium KW - Mice KW - Pathology KW - Urine KW - Gestation KW - Sodium arsenite KW - Urinary bladder KW - Pregnancy KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Induction+of+Urinary+Bladder+Pathology+in+Male+and+Female+C3H+Mice+Exposed+to+Sodium+Arsenite+from+Gestation+through+Young+Adulthood&rft.au=Ahlborn%2C+G%3BGrindstaff%2C+R%3BAllen%2C+J%3BNelson%2C+G%3BKitchin%2C+K%3BPreston%2C+J%3BWaalkes%2C+M%3BDiwan%2C+B%3BDelker%2C+D&rft.aulast=Ahlborn&rft.aufirst=G&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Perfluorooctanoic Acid and WY 14,643 Treatment Induced Peroxisome Proliferation in Livers of Wild-Type but not PPARa-null Mice. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556390; 4535503 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Lau, C AU - Abbott, B D AU - Wolf, D C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Mice KW - Liver KW - Perfluorooctanoic acid KW - Peroxisomes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556390?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Perfluorooctanoic+Acid+and+WY+14%2C643+Treatment+Induced+Peroxisome+Proliferation+in+Livers+of+Wild-Type+but+not+PPARa-null+Mice.&rft.au=Lau%2C+C%3BAbbott%2C+B+D%3BWolf%2C+D+C&rft.aulast=Lau&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Developmental Toxicity of Polybrominated Diphenyl Ether 47 in the Amphibian Model Species Xenopus Laevis T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556273; 4535573 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Degitz, S J AU - Holcombe, G W AU - Kosian, P A AU - Butterworth, B C AU - Tietge, J E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Polybrominated diphenyl ethers KW - Amphibians KW - Toxicity KW - Models KW - Biological development KW - Amphibiotic species KW - Xenopus laevis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Developmental+Toxicity+of+Polybrominated+Diphenyl+Ether+47+in+the+Amphibian+Model+Species+Xenopus+Laevis&rft.au=Degitz%2C+S+J%3BHolcombe%2C+G+W%3BKosian%2C+P+A%3BButterworth%2C+B+C%3BTietge%2C+J+E&rft.aulast=Degitz&rft.aufirst=S&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Low-Dose Thyroid Insufficiency: Impact on Neurodevelopment T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556253; 4535406 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Gilbert, M E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Thyroid KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Low-Dose+Thyroid+Insufficiency%3A+Impact+on+Neurodevelopment&rft.au=Gilbert%2C+M+E&rft.aulast=Gilbert&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Metabolism of Pentavalent and Trivalent Dimethylated Arsenic in the Mouse T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556212; 4536084 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Hughes, M F AU - Adair, B M AU - Edwards, B C AU - Thomas, D J AU - Creed, J T AU - Conklin, S AU - Styblo, M AU - Devesa, V AU - Kenyon, E M Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Metabolism KW - Arsenic KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556212?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Metabolism+of+Pentavalent+and+Trivalent+Dimethylated+Arsenic+in+the+Mouse&rft.au=Hughes%2C+M+F%3BAdair%2C+B+M%3BEdwards%2C+B+C%3BThomas%2C+D+J%3BCreed%2C+J+T%3BConklin%2C+S%3BStyblo%2C+M%3BDevesa%2C+V%3BKenyon%2C+E+M&rft.aulast=Hughes&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Advances and Challenges Regarding Mode-of-Action in Human Health Risk Assessment T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40556184; 4535379 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Keshava, N AU - Sams, R Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Risk assessment KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556184?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Advances+and+Challenges+Regarding+Mode-of-Action+in+Human+Health+Risk+Assessment&rft.au=Keshava%2C+N%3BSams%2C+R&rft.aulast=Keshava&rft.aufirst=N&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative In Vitro Pulmonary Toxicity of Engineered, Manufactured, and Environmental Nanoparticles T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555926; 4535905 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Dreher, K AU - Rhodes, S AU - Tycz, Z AU - Snyder, R Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Toxicity KW - Lung KW - Nanoparticles KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555926?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Comparative+In+Vitro+Pulmonary+Toxicity+of+Engineered%2C+Manufactured%2C+and+Environmental+Nanoparticles&rft.au=Dreher%2C+K%3BRhodes%2C+S%3BTycz%2C+Z%3BSnyder%2C+R&rft.aulast=Dreher&rft.aufirst=K&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of Simazine (SIM) on Testicular Function in the Juvenile Wistar Rat. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555891; 4534925 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Kaydos, E AU - Ferrell, J AU - Cooper, R AU - Stoker, T E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Simazine KW - Herbicides KW - Testes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555891?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Effect+of+Simazine+%28SIM%29+on+Testicular+Function+in+the+Juvenile+Wistar+Rat.&rft.au=Kaydos%2C+E%3BFerrell%2C+J%3BCooper%2C+R%3BStoker%2C+T+E&rft.aulast=Kaydos&rft.aufirst=E&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Atrazine (ATR) and Metabolite, Diamino-S-Chlorotriazine (DACT), on the Hypothalamic-Pituitary-Adrenal (HPA)Axis in Rats T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555852; 4534896 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Laws, S C AU - Ferrell, J AU - Hotchkiss, M AU - Buckalew, A AU - Murr, A AU - Cooper, R Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Metabolites KW - Atrazine KW - Herbicides KW - Rats KW - Hypothalamic-pituitary-adrenal axis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555852?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Effects+of+Atrazine+%28ATR%29+and+Metabolite%2C+Diamino-S-Chlorotriazine+%28DACT%29%2C+on+the+Hypothalamic-Pituitary-Adrenal+%28HPA%29Axis+in+Rats&rft.au=Laws%2C+S+C%3BFerrell%2C+J%3BHotchkiss%2C+M%3BBuckalew%2C+A%3BMurr%2C+A%3BCooper%2C+R&rft.aulast=Laws&rft.aufirst=S&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Concentration/Duration/Effect (C X T) Relationships in Assessments of Health Risk from Acute Inhalation Exposures Comparison of Approaches T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555823; 4535999 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Woodall, G M AU - Gift, J S AU - Howard, A S AU - Pagan, I AU - Stanek, J AU - Foureman, G L Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Inhalation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Concentration%2FDuration%2FEffect+%28C+X+T%29+Relationships+in+Assessments+of+Health+Risk+from+Acute+Inhalation+Exposures+Comparison+of+Approaches&rft.au=Woodall%2C+G+M%3BGift%2C+J+S%3BHoward%2C+A+S%3BPagan%2C+I%3BStanek%2C+J%3BFoureman%2C+G+L&rft.aulast=Woodall&rft.aufirst=G&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Brain Cholinesterase Inhibition Produced by Propoxur and Depression of the Photic after Discharge of Flash Evoked Potentials in Long Evans Rats T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555805; 4535529 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Mwanza, J AU - Graff, J E AU - Spivey, C L AU - Herr, D W Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Cholinesterase KW - Brain KW - Rats KW - Depression KW - Evoked potentials KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Brain+Cholinesterase+Inhibition+Produced+by+Propoxur+and+Depression+of+the+Photic+after+Discharge+of+Flash+Evoked+Potentials+in+Long+Evans+Rats&rft.au=Mwanza%2C+J%3BGraff%2C+J+E%3BSpivey%2C+C+L%3BHerr%2C+D+W&rft.aulast=Mwanza&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of Toxicogenomics Data in Risk Assessment: A Case Study on Dibutyl Phthalate and Male Reproductive Developmental Effects T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555784; 4535982 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Euling, S Y AU - Makris, S AU - Sen, B AU - Kim, A S AU - Benson, B AU - Gaido, K W AU - Wilson, V S AU - Keshava, C AU - Keshava, N AU - White, L AU - Foster, P M AU - Androulakis, I P AU - Ovacik, M AU - Ierapetritou, M G AU - Gray, L E AU - Thompson, C AU - Barone, S AU - Chiu, W AU - William, W AU - Panos, G Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Phthalates KW - Case studies KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555784?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Use+of+Toxicogenomics+Data+in+Risk+Assessment%3A+A+Case+Study+on+Dibutyl+Phthalate+and+Male+Reproductive+Developmental+Effects&rft.au=Euling%2C+S+Y%3BMakris%2C+S%3BSen%2C+B%3BKim%2C+A+S%3BBenson%2C+B%3BGaido%2C+K+W%3BWilson%2C+V+S%3BKeshava%2C+C%3BKeshava%2C+N%3BWhite%2C+L%3BFoster%2C+P+M%3BAndroulakis%2C+I+P%3BOvacik%2C+M%3BIerapetritou%2C+M+G%3BGray%2C+L+E%3BThompson%2C+C%3BBarone%2C+S%3BChiu%2C+W%3BWilliam%2C+W%3BPanos%2C+G&rft.aulast=Euling&rft.aufirst=S&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Kidney Toxicogenomics of 2-Week Sodium and Potassium Bromate Exposure in F344 Male Rat T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555738; 4535971 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Geter, D AU - Ward, W AU - Delker, D AU - Allen, J AU - George, M AU - Knapp, G AU - DeAngelo, A AU - Owen, R Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Sodium KW - Kidneys KW - Potassium KW - Potassium bromate KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Kidney+Toxicogenomics+of+2-Week+Sodium+and+Potassium+Bromate+Exposure+in+F344+Male+Rat&rft.au=Geter%2C+D%3BWard%2C+W%3BDelker%2C+D%3BAllen%2C+J%3BGeorge%2C+M%3BKnapp%2C+G%3BDeAngelo%2C+A%3BOwen%2C+R&rft.aulast=Geter&rft.aufirst=D&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gene Expression Profiling of Hyperkeratotic Skin from Inner Mongolians Exposed to Arsenic T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555695; 4536078 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Bailey, K A AU - Xia, Y AU - Mo, J. AU - Mumford, J L AU - Thai, S Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Skin KW - Gene expression KW - Arsenic KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555695?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Gene+Expression+Profiling+of+Hyperkeratotic+Skin+from+Inner+Mongolians+Exposed+to+Arsenic&rft.au=Bailey%2C+K+A%3BXia%2C+Y%3BMo%2C+J.%3BMumford%2C+J+L%3BThai%2C+S&rft.aulast=Bailey&rft.aufirst=K&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gestational Exposure to the Atrazine Metabolites Diaminochlorotriazine and Hydroxyatrazine Alters Mammary Gland Development in Long Evans Rat T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555605; 4535296 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Stanko, J P AU - Fenton, S E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Metabolites KW - Atrazine KW - Herbicides KW - Mammary gland KW - Glands KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Gestational+Exposure+to+the+Atrazine+Metabolites+Diaminochlorotriazine+and+Hydroxyatrazine+Alters+Mammary+Gland+Development+in+Long+Evans+Rat&rft.au=Stanko%2C+J+P%3BFenton%2C+S+E&rft.aulast=Stanko&rft.aufirst=J&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Consideration of Therapeutic Dose for Development of Provisional Reference Dose (P-RfD) for Nitroglycerin T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40555006; 4535960 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Choudhury, H AU - Klotzbach, J Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Nitroglycerin KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40555006?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Consideration+of+Therapeutic+Dose+for+Development+of+Provisional+Reference+Dose+%28P-RfD%29+for+Nitroglycerin&rft.au=Choudhury%2C+H%3BKlotzbach%2C+J&rft.aulast=Choudhury&rft.aufirst=H&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Time-Course of Acute Neurotoxicity Produced by N-Methyl Carbamates in Preweanling Rats T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40554924; 4535528 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - McDaniel, K L AU - Phillips, P M AU - Moser, V C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Neurotoxicity KW - Rats KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40554924?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Time-Course+of+Acute+Neurotoxicity+Produced+by+N-Methyl+Carbamates+in+Preweanling+Rats&rft.au=McDaniel%2C+K+L%3BPhillips%2C+P+M%3BMoser%2C+V+C&rft.aulast=McDaniel&rft.aufirst=K&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative Evaluation of Risk Factors for Cardiovascular Disease (CVD) in Genetically Predisposed Rats T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40554730; 4535307 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Schladweiler, M C AU - Nyska, A AU - Ledbetter, A D AU - Wallenborn, J AU - Gottipolu, R R AU - Richards, J H AU - Thomas, R AU - Jaskot, R H AU - Shannahan, J AU - Crissman, K AU - Hatch, G E AU - Kodavanti, U P Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Cardiovascular diseases KW - Rats KW - Risk factors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40554730?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Comparative+Evaluation+of+Risk+Factors+for+Cardiovascular+Disease+%28CVD%29+in+Genetically+Predisposed+Rats&rft.au=Schladweiler%2C+M+C%3BNyska%2C+A%3BLedbetter%2C+A+D%3BWallenborn%2C+J%3BGottipolu%2C+R+R%3BRichards%2C+J+H%3BThomas%2C+R%3BJaskot%2C+R+H%3BShannahan%2C+J%3BCrissman%2C+K%3BHatch%2C+G+E%3BKodavanti%2C+U+P&rft.aulast=Schladweiler&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Measurement of Environmental Phenol Levels in the Urine of Lactating Women T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40554690; 4535300 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Hines, E P AU - Rayner, J L AU - Schmid, J S AU - Ye, X. AU - Calafat, A M AU - Fenton, S E Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Phenols KW - Urine KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40554690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Measurement+of+Environmental+Phenol+Levels+in+the+Urine+of+Lactating+Women&rft.au=Hines%2C+E+P%3BRayner%2C+J+L%3BSchmid%2C+J+S%3BYe%2C+X.%3BCalafat%2C+A+M%3BFenton%2C+S+E&rft.aulast=Hines&rft.aufirst=E&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Enhanced Toxicity of Charged Carbon Nanotubes and Ultrafine Carbon Black Particles T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40554289; 4535917 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Gilmour, I AU - Williams, W AU - McGee, J K AU - Saxena, R K Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Particulates KW - Black carbon KW - Carbon KW - Toxicity KW - Nanotubes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40554289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Enhanced+Toxicity+of+Charged+Carbon+Nanotubes+and+Ultrafine+Carbon+Black+Particles&rft.au=Gilmour%2C+I%3BWilliams%2C+W%3BMcGee%2C+J+K%3BSaxena%2C+R+K&rft.aulast=Gilmour&rft.aufirst=I&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Predicting Age-Dependent Pharmacokinetics of Six Volatile Organic Compounds in the Rat Utilizing Physiologically-Based Pharmacokinetic Modeling T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40554069; 4535806 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Rodriguez, C E AU - Barton, H A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Pharmacokinetics KW - Volatile organic compounds KW - Organic compounds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40554069?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Predicting+Age-Dependent+Pharmacokinetics+of+Six+Volatile+Organic+Compounds+in+the+Rat+Utilizing+Physiologically-Based+Pharmacokinetic+Modeling&rft.au=Rodriguez%2C+C+E%3BBarton%2C+H+A&rft.aulast=Rodriguez&rft.aufirst=C&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gene Profiling in Wild Type and PPARa Null Mice Exposed to PFOA. T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40553996; 4535652 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Rosen, M AU - Abbott, B D AU - Schmid, J R AU - Zehr, R D AU - Das, K P AU - Wolf, C J AU - Lau, C S Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Mice KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40553996?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Gene+Profiling+in+Wild+Type+and+PPARa+Null+Mice+Exposed+to+PFOA.&rft.au=Rosen%2C+M%3BAbbott%2C+B+D%3BSchmid%2C+J+R%3BZehr%2C+R+D%3BDas%2C+K+P%3BWolf%2C+C+J%3BLau%2C+C+S&rft.aulast=Rosen&rft.aufirst=M&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Poultry Production and Arsenic in Drinking Water from Groundwater in the Eastern and Southern Shore Counties of Maryland T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40553654; 4535428 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Nweke, O AU - Silbergeld, E AU - Bandeen-Roche, K AU - Lees, P AU - Aposhian, V AU - Gallicchio, L AU - Guallar, E AU - Alberg, A Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - USA, Maryland KW - Aquifers KW - Shores KW - Ground water KW - Poultry KW - Drinking water KW - Arsenic KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40553654?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Poultry+Production+and+Arsenic+in+Drinking+Water+from+Groundwater+in+the+Eastern+and+Southern+Shore+Counties+of+Maryland&rft.au=Nweke%2C+O%3BSilbergeld%2C+E%3BBandeen-Roche%2C+K%3BLees%2C+P%3BAposhian%2C+V%3BGallicchio%2C+L%3BGuallar%2C+E%3BAlberg%2C+A&rft.aulast=Nweke&rft.aufirst=O&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Thyroid Hormone Disruption: From Kinetics to Dynamics T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40553553; 4535403 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Crofton, K M AU - Fisher, J W Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Kinetics KW - Hormones KW - Thyroid hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40553553?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=Thyroid+Hormone+Disruption%3A+From+Kinetics+to+Dynamics&rft.au=Crofton%2C+K+M%3BFisher%2C+J+W&rft.aulast=Crofton&rft.aufirst=K&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - PPARalpha-Dependent Gene Expression Changes in the Mouse Liver after Exposure to Peroxisome Proliferators T2 - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AN - 40552528; 4535446 JF - 46th Annual Meeting and ToxExpo of the Society of Toxicology (SOT 2007) AU - Ren, H AU - Vallanat, B AU - Bao, W AU - Wolfinger, R AU - Corton, C Y1 - 2007/03/25/ PY - 2007 DA - 2007 Mar 25 KW - Liver KW - Gene expression KW - Peroxisomes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40552528?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.atitle=PPARalpha-Dependent+Gene+Expression+Changes+in+the+Mouse+Liver+after+Exposure+to+Peroxisome+Proliferators&rft.au=Ren%2C+H%3BVallanat%2C+B%3BBao%2C+W%3BWolfinger%2C+R%3BCorton%2C+C&rft.aulast=Ren&rft.aufirst=H&rft.date=2007-03-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=46th+Annual+Meeting+and+ToxExpo+of+the+Society+of+Toxicology+%28SOT+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2007/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Use of carbon stable isotope to investigate chloromethane formation in the electrolytic dechlorination of trichloroethylene AN - 19686427; 7482280 AB - Carbon stable isotope trichloroethylene ( super(1) super(3)C TCE) was used to investigate the formation of chloromethane (CM) during the electrolytic dechlorination of trichloroethylene (TCE) at a granular-graphite packed cathode. A method was developed to use a conventional GC/MS to analyze and quantify regular and super(1) super(3)C TCE and their dechlorination products. The concentration of a super(1) super(3)C compound can be calculated, based on the concentration of its regular counterpart, from the response ratio of two fragments of different mass per charge values from the compounds in a sample and two characteristic MS spectrum ratios: one is the response ratio of the two fragments of the regular compound, and the other is the response ratio of the corresponding fragments of the regular and super(1) super(3)C compounds at the same concentrations. The method was used to analyze the regular and super(1) super(3)C compounds observed in an experiment of dechlorination in an ammonium acetate solution that contained both regular TCE and super(1) super(3)C TCE. Results of analysis confirmed that CM was not a direct product of TCE dechlorination at the granular graphite cathode that cis-DCE was an intermediate product of TCE dechlorination, and that 1,1-DCE was not a dechlorination product. JF - Journal of Hazardous Materials AU - Fang, Y AU - Al-Abed AD - USEPA 26 W. Martin Luther King Dr. Cincinnati, OH 45268, United States, Al-Abed.Souhail@epa.gov Y1 - 2007/03/22/ PY - 2007 DA - 2007 Mar 22 SP - 729 EP - 735 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 141 IS - 3 SN - 0304-3894, 0304-3894 KW - Toxicology Abstracts KW - Cathodes KW - Dechlorination KW - Guanylate cyclase KW - Isotopes KW - Carbon KW - Graphite KW - Trichloroethylene KW - Ammonium acetate KW - chloromethane KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19686427?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hazardous+Materials&rft.atitle=Use+of+carbon+stable+isotope+to+investigate+chloromethane+formation+in+the+electrolytic+dechlorination+of+trichloroethylene&rft.au=Fang%2C+Y%3BAl-Abed&rft.aulast=Fang&rft.aufirst=Y&rft.date=2007-03-22&rft.volume=141&rft.issue=3&rft.spage=729&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hazardous+Materials&rft.issn=03043894&rft_id=info:doi/10.1016%2Fj.jhazmat.2006.07.036 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-03-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Cathodes; Guanylate cyclase; Dechlorination; Isotopes; Graphite; Carbon; Trichloroethylene; Ammonium acetate; chloromethane DO - http://dx.doi.org/10.1016/j.jhazmat.2006.07.036 ER - TY - JOUR T1 - Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites. AN - 70288160; 16698003 AB - 1,3-Butadiene (BTD) is an important commodity chemical and air pollutant that has been shown to be a potent carcinogen in mice, and to a lesser extent, a carcinogen in rats. To better assess butadiene's carcinogenic risk to humans, it is important to understand its mode of action and how this relates to differences in responses among species. In a series of in vitro experiments, lymphocytes from rats, mice, and humans were exposed to 3,4-epoxy-1-butene (EB) or 1,2:3,4-diepoxybutane (DEB) for 1h at the G(0) stage of the cell cycle, stimulated to divide, and cultured to assess the ability of these metabolites to induce sister chromatid exchange (SCE) and chromosome aberrations (CAs). EB induced no increases in SCEs or CAs in the cells from the three species. DEB was a potent SCE- and CA-inducer, with the results being similar in each rodent species. The response for SCEs seen in the human cells was more complex, with genetic polymorphism for glutathione-S-transferases (GST) possibly modulating the response. The single cell gel electrophoresis assay was used on genetically engineered V79 cell lines to investigate a possible influence of GST status. Experiments were also conducted to investigate the reason for EB's failure to induce SCEs or CAs in G(0) cells. The results indicate that EB-induced DNA damage was repaired before DNA synthesis in unstimulated lymphocytes, but EB caused a large increase in SCEs if actively cycling cells were treated. Thus, the results indicate that DEB damage is persistent in G(0) cells, and DEB is a much more potent genotoxicant than EB. The carcinogenic effect of butadiene will most likely depend on the degree to which DEB is produced and reaches target tissues, and to a lesser extent on the ability of EB to reach actively dividing or repair deficient cells. JF - Chemico-biological interactions AU - Kligerman, A D AU - Hu, Y AD - B143-06, Cellular Toxicology Branch, Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. kligerman.andrew@epa.gov Y1 - 2007/03/20/ PY - 2007 DA - 2007 Mar 20 SP - 132 EP - 139 VL - 166 IS - 1-3 SN - 0009-2797, 0009-2797 KW - Butadienes KW - 0 KW - Epoxy Compounds KW - Mutagens KW - 3,4-epoxy-1-butene KW - 478ERR5NKR KW - erythritol anhydride KW - 60OB65YNAB KW - glutathione S-transferase T1 KW - EC 2.5.1.- KW - Glutathione Transferase KW - EC 2.5.1.18 KW - Glutathione KW - GAN16C9B8O KW - Index Medicus KW - Animals KW - Dose-Response Relationship, Drug KW - Glutathione -- metabolism KW - Humans KW - Glutathione Transferase -- metabolism KW - Mutagens -- toxicity KW - Mice KW - Cell Separation KW - Rats KW - Chromosome Aberrations -- drug effects KW - Cells, Cultured KW - Mutagens -- metabolism KW - Sister Chromatid Exchange -- drug effects KW - Lymphocytes -- enzymology KW - Resting Phase, Cell Cycle -- drug effects KW - Lymphocytes -- drug effects KW - Cell Cycle -- drug effects KW - Butadienes -- toxicity KW - Epoxy Compounds -- metabolism KW - Epoxy Compounds -- toxicity KW - Butadienes -- metabolism KW - DNA Damage -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70288160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemico-biological+interactions&rft.atitle=Some+insights+into+the+mode+of+action+of+butadiene+by+examining+the+genotoxicity+of+its+metabolites.&rft.au=Kligerman%2C+A+D%3BHu%2C+Y&rft.aulast=Kligerman&rft.aufirst=A&rft.date=2007-03-20&rft.volume=166&rft.issue=1-3&rft.spage=132&rft.isbn=&rft.btitle=&rft.title=Chemico-biological+interactions&rft.issn=00092797&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-23 N1 - Date created - 2007-03-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Analysis of a gas-phase partitioning tracer test conducted in an unsaturated fractured-clay formation AN - 21061266; 8260940 AB - The gas-phase partitioning tracer method was used to estimate non-aqueous phase liquid (NAPL), water, and air saturations in the vadose zone at a chlorinated-solvent contaminated field site in Tucson, AZ. The tracer test was conducted in a fractured-clay system that is the confining layer for the underlying regional aquifer. Three suites of three tracers were injected into wells located 14, 24, and 24 m from a single, central extraction well. The tracers comprised noble gases (traditionally thought to be nonsorbing), alkanes (primarily water partitioning), perfluorides (primarily NAPL partitioning), and halons (both NAPL and water partitioning). Observations of vacuum response were consistent with flow in a fractured system. The halon tracers exhibited the greatest amount of retardation, and helium and the perfluoride tracers the least. The alkane tracers were unexpectedly more retarded than the perfluoride tracers, indicating low NAPL saturations and high water saturations. An NAPL saturation of 0.01, water saturation of 0.215, and gas saturation of 0.775 was estimated based on analysis of the suite of tracers comprising helium, perfluoromethylcyclohexane and dibromodifluoromethane, which was considered to be the most robust set. The estimated saturations compare reasonably well to independently determined values. JF - Journal of Contaminant Hydrology AU - Simon, MA AU - Brusseau, M L AD - 26 West Martin Luther King Drive, Cincinnati, OH 45268, USA, simon.michelle@epa.gov Y1 - 2007/03/20/ PY - 2007 DA - 2007 Mar 20 SP - 146 EP - 158 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 90 IS - 3-4 SN - 0169-7722, 0169-7722 KW - Aqualine Abstracts; Pollution Abstracts; Water Resources Abstracts KW - Aquifers KW - Groundwater Pollution KW - Tracers KW - Pollutants KW - Nonaqueous phase liquids KW - Hydrology KW - USA, Arizona, Tucson KW - Vadose Water KW - Saturation KW - Gases KW - Aquifer Testing KW - Helium KW - Groundwater pollution KW - Groundwater KW - SW 3010:Identification of pollutants KW - P 2000:FRESHWATER POLLUTION KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21061266?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Contaminant+Hydrology&rft.atitle=Analysis+of+a+gas-phase+partitioning+tracer+test+conducted+in+an+unsaturated+fractured-clay+formation&rft.au=Simon%2C+MA%3BBrusseau%2C+M+L&rft.aulast=Simon&rft.aufirst=MA&rft.date=2007-03-20&rft.volume=90&rft.issue=3-4&rft.spage=146&rft.isbn=&rft.btitle=&rft.title=Journal+of+Contaminant+Hydrology&rft.issn=01697722&rft_id=info:doi/10.1016%2Fj.jconhyd.2006.09.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Aquifers; Tracers; Gases; Nonaqueous phase liquids; Groundwater pollution; Hydrology; Helium; Pollutants; Aquifer Testing; Groundwater Pollution; Groundwater; Saturation; Vadose Water; USA, Arizona, Tucson DO - http://dx.doi.org/10.1016/j.jconhyd.2006.09.010 ER - TY - JOUR T1 - Cancer risk assessment for 1,3-butadiene: Data integration opportunities AN - 20804106; 7748292 AB - The US Environmental Protection Agency recently released its new guidelines for carcinogen risk assessment together with supplemental guidance for assessing susceptibility from early-life exposure to carcinogens. In particular, these guidelines encourage the use of mechanistic data in support of dose-response characterization at doses below those at which an increase in tumor frequency over background levels might be detected. In this context of the utility of mechanistic data for human cancer risk assessment, the International Life Sciences Institute (ILSI) has developed a human relevance framework (HRF) that can be used to assess the plausibility of a mode of action (MoA) described for animal models operating in humans. The MoA is described as a sequence of key events and processes that result in an adverse outcome. A key event is a measurable precursor step that is in itself a necessary element of the MoA or is a bioindicator for such an element. A number of cellular and molecular perturbations have been identified as key events whereby DNA-reactive chemicals can produce tumors. These include DNA adducts in target tissues, gene mutations and/or chromosomal alterations in target tissues and enhanced cell proliferation in target tissues. This type of data integration approach to quantitative cancer risk assessment can be applied to 1,3-butadiene, for example, using data on biomarkers in exposed Czech workers. For this study, an extensive range of biomarkers of exposure and response was assessed, including: polymorphisms in metabolizing enzymes; urinary concentrations of several metabolites of 1,3-butadiene; hemoglobin adducts; HPRT mutations in T-lymphocytes; chromosomal aberrations by FISH and conventional staining procedures; sister chromatid exchanges. Exposure levels were monitored in a comprehensive fashion. For risk assessment purposes, these data need to be considered in the context of how they inform the MoA for leukemia, the tumor type reported to be increased in synthetic rubber workers exposed to 1,3-butadiene. Also, for the HRF it is necessary to establish key events for a MoA in rodents for the induction of tumors by 1,3-butadiene. There is clearly a species difference in sensitivity to tumor induction, with mice being much more sensitive than rats; key events need to explain this difference. For butadiene, the MoA is DNA-reactivity and subsequent mutagenicity and so following the EPA's cancer guidelines, a linear extrapolation is used from the point of departure (POD), unless additional data support a non-linear extrapolation. For the present case, the human bioindicator data are not informative as far as dose-response characterization is concerned. Mouse chromosome aberration data for in vivo exposures might be used for establishing a POD, with linear extrapolation from this POD. The available cytogenetic data from rodent studies appear to be sufficiently extensive and consistent for this to be a viable approach. This approach of using MoA and key events to establish the human relevance can lead to the development of specific informative bioindicators of response that can be used as surrogates to predict the shape of the tumor dose response curve at low doses. Truly informative predictors of tumor responses should be able to provide estimates of human tumor frequencies at low, environmental exposures to 1,3-butadiene. JF - Chemico-Biological Interactions AU - Preston, R J AD - National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, United States Y1 - 2007/03/20/ PY - 2007 DA - 2007 Mar 20 SP - 150 EP - 155 VL - 166 IS - 1-3 SN - 0009-2797, 0009-2797 KW - Toxicology Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - Risk assessment KW - Animal models KW - Metabolites KW - Carcinogens KW - Hemoglobin KW - Integration KW - Leukemia KW - 1,3-Butadiene KW - Lymphocytes T KW - Chromosome aberrations KW - Fluorescence in situ hybridization KW - DNA adducts KW - Mutagenicity KW - Data processing KW - Point mutation KW - Enzymes KW - sister chromatids KW - Rubber KW - Tumors KW - biomarkers KW - Cancer KW - Background levels KW - Cell proliferation KW - Indicator species KW - N 14820:DNA Metabolism & Structure KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20804106?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemico-Biological+Interactions&rft.atitle=Cancer+risk+assessment+for+1%2C3-butadiene%3A+Data+integration+opportunities&rft.au=Preston%2C+R+J&rft.aulast=Preston&rft.aufirst=R&rft.date=2007-03-20&rft.volume=166&rft.issue=1-3&rft.spage=150&rft.isbn=&rft.btitle=&rft.title=Chemico-Biological+Interactions&rft.issn=00092797&rft_id=info:doi/10.1016%2Fj.cbi.2006.03.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; DNA adducts; Mutagenicity; Data processing; Point mutation; Animal models; Rubber; sister chromatids; Enzymes; Metabolites; Tumors; Carcinogens; biomarkers; Cancer; Hemoglobin; Leukemia; Integration; 1,3-Butadiene; Background levels; Lymphocytes T; Cell proliferation; Chromosome aberrations; Fluorescence in situ hybridization; Indicator species DO - http://dx.doi.org/10.1016/j.cbi.2006.03.009 ER - TY - JOUR T1 - Chloroprene: Overview of studies under consideration for the development of an IRIS assessment AN - 20376927; 7748304 AB - Beta-chloroprene (C sub(4)H sub(5)CI, chloroprene, 2-chloro-1,3-butadiene, CASRN 126-99-8) is a volatile, flammable liquid monomer utilized primarily in the manufacture of neoprene (polychloroprene) elastomer used in belts, hoses, gloves, wire coatings, and tubing. Absorption into the body occurs primarily via the respiratory system and may occur via the gastrointestinal tract or the skin. Once absorbed, chloroprene is widely distributed as evidenced by effects in several target organs including nose and lung, liver, and skin. Chloroprene metabolism is believed to include cytochrome P450 oxidation to a monoepoxide, hydrolysis by epoxide hydrolases, and glutathione conjugation. Similar to 1,3-butadiene, the epoxide is considered to be the toxic moiety, and species differences in metabolic capacity may influence the severity of effects as well as what tissues are affected. EPA has not previously developed an assessment of chloroprene's potential for human health effects. Existing human epidemiological studies offer little data on noncancer effects, and the associations of exposure with increased cancer (liver and lung) mortality reported are inconclusive. Recent epidemiological studies (submitted for publication) could offer information that may impact chloroprene's health assessment Multiple-site tumors have been reported in rats and mice exposed to chloroprene by inhalation; nevertheless, there are marked differences in strain sensitivities (i.e., tumors in F344 rats versus no tumors in Wistar rats). Recently developed physiologically based toxicokinetic models may allow for the resolution of species and tissue differences and sensitivities as well as exposure--dose-response relationships relevant to humans. (This presentation does not necessarily reflect EPA policy.). JF - Chemico-Biological Interactions AU - Pagan, I AD - U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Mailcode B-243-01, 109 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA Y1 - 2007/03/20/ PY - 2007 DA - 2007 Mar 20 SP - 341 EP - 351 VL - 166 IS - 1-3 SN - 0009-2797, 0009-2797 KW - Toxicology Abstracts KW - Inhalation KW - Epoxides KW - Glutathione KW - Liver cancer KW - Animal models KW - Elastomers KW - Models KW - 1,3-Butadiene KW - Gloves KW - Epoxide hydrolase KW - Lung cancer KW - Mortality KW - Skin KW - Tumors KW - Hydrolysis KW - Cancer KW - Monomers KW - Volatiles KW - Lung KW - Reviews KW - Oxidation KW - Liver KW - Nose KW - Gastrointestinal tract KW - Cytochrome P450 KW - Metabolism KW - Coatings KW - Respiratory system KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20376927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemico-Biological+Interactions&rft.atitle=Chloroprene%3A+Overview+of+studies+under+consideration+for+the+development+of+an+IRIS+assessment&rft.au=Pagan%2C+I&rft.aulast=Pagan&rft.aufirst=I&rft.date=2007-03-20&rft.volume=166&rft.issue=1-3&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=Chemico-Biological+Interactions&rft.issn=00092797&rft_id=info:doi/10.1016%2Fj.cbi.2006.12.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Inhalation; Epoxides; Glutathione; Liver cancer; Animal models; Elastomers; Models; 1,3-Butadiene; Gloves; Epoxide hydrolase; Lung cancer; Mortality; Skin; Tumors; Hydrolysis; Cancer; Monomers; Lung; Volatiles; Reviews; Oxidation; Liver; Nose; Cytochrome P450; Gastrointestinal tract; Metabolism; Respiratory system; Coatings DO - http://dx.doi.org/10.1016/j.cbi.2006.12.001 ER - TY - JOUR T1 - PBPK models in risk assessment--A focus on chloroprene AN - 20373080; 7748305 AB - Mathematical models are increasingly being used to simulate events in the exposure-response continuum, and to support quantitative predictions of risks to human health. Physiologically based pharmacokinetic (PBPK) models address that portion of the continuum from an external chemical exposure to an internal dose at a target site. Essential data needed to develop a PBPK model include values of key physiological parameters (e.g., tissue volumes, blood flow rates) and chemical specific parameters (rate of chemical absorption, distribution, metabolism, and elimination) for the species of interest PBPK models are commonly used to: (1) predict concentrations of an internal dose over time at a target site following external exposure via different routes and/or durations; (2) predict human internal concentration at a target site based on animal data by accounting for toxicokinetic and physiological differences; and (3) estimate variability in the internal dose within a human population resulting from differences in individual pharmacokinetics. Himmelstein et al. [M.W. Himmelstein, S.C. Carpenter, P.M. Hinderliter, Kinetic modeling of beta-chloroprene metabolism. I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans, Toxicol. Sci. 79 (1) (2004) 18-27; M.W. Himmelstein, S.C. Carpenter, M.V. Evans, P.M. Hinderliter, E.M. Kenyon, Kinetic modeling of beta-chloroprene metabolism. II. The application of physiologically based modeling for cancer dose response analysis, Toxicol. Sci. 79 (1) (2004) 28-37] developed a PBPK model for chloroprene (2-chloro-1,3-butadiene; CD) that simulates chloroprene disposition in rats, mice, hamsters, or humans following an inhalation exposure. Values for the CD-PBPK model metabolic parameters were obtained from in vitro studies, and model simulations compared to data from in vivo gas uptake studies in rats, hamsters, and mice. The model estimate for total amount of metabolite in lung correlated better with rodent tumor incidence than did the external dose. Based on this PBPK model analytical approach, Himmelstein et al. [M.W. Himmelstein, S.C. Carpenter, M.V. Evans, P.M. Hinderliter, E.M. Kenyon, Kinetic modeling of beta-chloroprene metabolism. II. The application of physiologically based modeling for cancer dose response analysis, Toxicol. Sci. 79 (1) (2004) 28-37; M.W. Himmelstein, R. Leonard, R. Valentine, Kinetic modeling of beta -chloroprene metabolism: default and physiologically-based modeling approaches for cancer dose response, in: IISRP Symposium on Evaluation of Butadiene & Chloroprene Health Effects, September 21, 2005, TBD--reference in this proceedings issue of Chemical-Biological Interactions] propose that observed species differences in the lung tumor dose-response result from differences in CD metabolic rates. The CD-PBPK model has not yet been submitted to EPA for use in developing the IRIS assessment for chloroprene, but is sufficiently developed to be considered. The process that EPA uses to evaluate PBPK models is discussed, as well as potential applications for the CO-PBPK model in an IRIS assessment. JF - Chemico-Biological Interactions AU - DeWoskin, R S AD - US EPA/NCEA (National Center for Environmental Assessment), Mail Drop B243-01, Research Triangle Park, NC 27711, United States Y1 - 2007/03/20/ PY - 2007 DA - 2007 Mar 20 SP - 352 EP - 359 VL - 166 IS - 1-3 SN - 0009-2797, 0009-2797 KW - Toxicology Abstracts KW - Inhalation KW - Data processing KW - Mathematical models KW - Metabolic rate KW - Animal models KW - Metabolites KW - Disposition KW - Tumors KW - Pharmacokinetics KW - Cancer KW - Models KW - Lung KW - Dose-response effects KW - Kinetics KW - Liver KW - Metabolism KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20373080?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemico-Biological+Interactions&rft.atitle=PBPK+models+in+risk+assessment--A+focus+on+chloroprene&rft.au=DeWoskin%2C+R+S&rft.aulast=DeWoskin&rft.aufirst=R&rft.date=2007-03-20&rft.volume=166&rft.issue=1-3&rft.spage=352&rft.isbn=&rft.btitle=&rft.title=Chemico-Biological+Interactions&rft.issn=00092797&rft_id=info:doi/10.1016%2Fj.cbi.2007.01.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Inhalation; Mathematical models; Data processing; Animal models; Metabolic rate; Disposition; Metabolites; Tumors; Cancer; Pharmacokinetics; Models; Lung; Kinetics; Dose-response effects; Liver; Metabolism DO - http://dx.doi.org/10.1016/j.cbi.2007.01.016 ER - TY - CPAPER T1 - Base Catalyzed Decomposition (BCD) of PCB and Dioxin Contaminated Condensate Oil from the Remediation of the Warrren County Landfill, NC T2 - 17th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AN - 40581723; 4548642 JF - 17th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AU - Lyons, Terrence M Y1 - 2007/03/19/ PY - 2007 DA - 2007 Mar 19 KW - Landfills KW - Dioxin KW - Waste disposal sites KW - Bioremediation KW - Oil pollution KW - PCB KW - Decomposition KW - Condensates KW - Polychlorinated biphenyls KW - Chlorinated hydrocarbons KW - Degradation KW - Pollution control KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40581723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=17th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Base+Catalyzed+Decomposition+%28BCD%29+of+PCB+and+Dioxin+Contaminated+Condensate+Oil+from+the+Remediation+of+the+Warrren+County+Landfill%2C+NC&rft.au=Lyons%2C+Terrence+M&rft.aulast=Lyons&rft.aufirst=Terrence&rft.date=2007-03-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=17th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.aehs.com/conferences/westcoast/pdfs/PRELIMINARYPROGRAM07.pd f LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Polychlorinated Biphenols Engineering Bulletin T2 - 17th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AN - 40581043; 4548687 JF - 17th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AU - Lyons, Terrence M Y1 - 2007/03/19/ PY - 2007 DA - 2007 Mar 19 KW - Chlorinated hydrocarbons KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40581043?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=17th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Polychlorinated+Biphenols+Engineering+Bulletin&rft.au=Lyons%2C+Terrence+M&rft.aulast=Lyons&rft.aufirst=Terrence&rft.date=2007-03-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=17th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.aehs.com/conferences/westcoast/pdfs/PRELIMINARYPROGRAM07.pd f LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Characterization of naphtho[1,2-a]pyrene and naphtho[1,2-e]pyrene DNA adducts in C3H10T1/2 fibroblasts. AN - 69023692; 16814461 AB - Polycyclic aromatic hydrocarbons (PAHs) are a class of carcinogenic chemicals that are ubiquitous in the environment. Fjord-region naphthopyrene isomers are structurally similar to the potent fjord-region PAH carcinogen dibenzo[a,l]pyrene and thus have the potential to be potent carcinogens. Naphtho[1,2-a]pyrene (N[1,2-a]P) exhibited similar bacterial mutagenicity and morphological cell transforming activity when compared to benzo[a]pyrene (B[a]P), whereas the structural isomer, naphtho[1,2-e]pyrene (N[1,2-e]P) was inactive is these bioassays. In this study, we examined the formation of DNA adducts in C3H10T1/2Cl8 (C3H10T1/2) mouse embryo fibroblasts exposed to N[1,2-a]P or N[1,2-e]P and their respective dihydrodiols. The DNA adducts were characterized by co-chromatography with reaction products from anti-N[1,2-a]P diol epoxide (DE) or anti-N[1,2-e]PDE and polydeoxyadenosine (dAdo) or oligodeoxyguanosine (dGuo). C3H10T1/2 fibroblasts exposed to N[1,2-a]P or N[1,2-a]P-9,10-diol produced both anti-N[1,2-a]P-DE-dAdo and -dGuo adducts with total DNA adduction levels of 22.2 to 33.3 pmol DNA adducts/mug DNA. C3H10T1/2 fibroblasts exposed to N[1,2-e]P produced 2 major and 1 minor adducts. C3H10T1/2 fibroblasts exposed to N[1,2-e]P-11,12-diol produced 2 major adducts. All of the identified adducts were anti-N[1,2-e]PDE-dGuo and -dAdo adducts. While the total DNA adduct level in N[1,2-e]P-11,12-diol-treated fibroblasts was extremely high, 105.9 pmol DNA adducts/mug DNA, the level in N[1,2-e]P-treated fibroblasts was 1.47 pmol DNA adducts/microg DNA. We conclude that lack of biological activity of N[1,2-e]P may be related to its inability to form sufficient amounts of N[1,2-e]P-11,12-diol, which would then be metabolized to sufficient amounts of anti-N[1,2-e]PDE needed to transform these fibroblasts. JF - Cancer letters AU - Nelson, Garret AU - Ross, Jeffrey A AU - Pimentel, Maria AU - Desai, Dhimant AU - Sharma, Arun K AU - Amin, Shantu AU - Nesnow, Stephen AD - Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, MD-B143-06, Research Triangle Park, NC 27711, USA. Y1 - 2007/03/18/ PY - 2007 DA - 2007 Mar 18 SP - 309 EP - 317 VL - 247 IS - 2 SN - 0304-3835, 0304-3835 KW - DNA Adducts KW - 0 KW - Naphthalenes KW - Pyrenes KW - naphtho(1,2-a)pyrene KW - naphtho(1,2-e)pyrene KW - Index Medicus KW - Animals KW - Fibroblasts -- chemistry KW - Mice, Inbred C3H KW - Mice KW - Cell Line KW - Pyrenes -- chemistry KW - Naphthalenes -- chemistry KW - DNA Adducts -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69023692?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+letters&rft.atitle=Characterization+of+naphtho%5B1%2C2-a%5Dpyrene+and+naphtho%5B1%2C2-e%5Dpyrene+DNA+adducts+in+C3H10T1%2F2+fibroblasts.&rft.au=Nelson%2C+Garret%3BRoss%2C+Jeffrey+A%3BPimentel%2C+Maria%3BDesai%2C+Dhimant%3BSharma%2C+Arun+K%3BAmin%2C+Shantu%3BNesnow%2C+Stephen&rft.aulast=Nelson&rft.aufirst=Garret&rft.date=2007-03-18&rft.volume=247&rft.issue=2&rft.spage=309&rft.isbn=&rft.btitle=&rft.title=Cancer+letters&rft.issn=03043835&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-04-30 N1 - Date created - 2007-02-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - Solving Problem Approach to Solid Waste Emergency Response: A Case Study of Metropolitan Bandung T2 - 22nd International Conference on Solid Waste Technology and Management AN - 40596580; 4548811 JF - 22nd International Conference on Solid Waste Technology and Management AU - Rachmat, Agus AU - Perdana, Arief Y1 - 2007/03/18/ PY - 2007 DA - 2007 Mar 18 KW - Case studies KW - Solid wastes KW - Solid impurities KW - Emergencies KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40596580?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=22nd+International+Conference+on+Solid+Waste+Technology+and+Management&rft.atitle=Solving+Problem+Approach+to+Solid+Waste+Emergency+Response%3A+A+Case+Study+of+Metropolitan+Bandung&rft.au=Rachmat%2C+Agus%3BPerdana%2C+Arief&rft.aulast=Rachmat&rft.aufirst=Agus&rft.date=2007-03-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=22nd+International+Conference+on+Solid+Waste+Technology+and+Management&rft.issn=&rft_id=info:doi/ L2 - http://www2.widener.edu/~sxw0004/22CONF.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Connectivity in urbanizing landscapes: The importance of habitat configuration, urban area size, and dispersal AN - 860372208; 13880226 AB - Human activities affect both the amount and configuration of habitat. These changes have important ecological implications that can be measured as changes in landscape connectivity. I investigated how urbanization interacts with the initial amount and aggregation of habitat to change dispersal potential, restoration potential, and the risk of spatially extensive disturbances. I used a factorial set of simulated landscapes and subjected each landscape to habitat loss by overlaying 66 different US urban areas. I used a common connectivity metric, CONNECT, to assess the magnitude and direction of changes for a range of dispersal distances. My results show that the relationship between habitat loss and connectivity loss is non-linear and subject to interactions between the spatial patterns of habitat distribution, urban morphology, and dispersal capabilities. The implications of a given urban form vary widely as a function of habitat distribution and dispersal capabilities. This implies that impact assessments, restoration activities, and conservation planning should consider historical habitat distribution when evaluating observed changes in connectivity. While my results clearly show that more aggregated or continuous habitats are more vulnerable to connectivity loss, this approach can also be used to identify landscapes where restoring connectivity will be particularly effective, for example through placement of stepping stone habitats. JF - Urban Ecosystems AU - Bierwagen, Britta G AD - Donald Bren School of Environmental Science & Management, University of California, Santa Barbara, Santa Barbara, CA, 93106, USA, bierwagen.britta@epa.gov Y1 - 2007/03// PY - 2007 DA - Mar 2007 SP - 29 EP - 42 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 10 IS - 1 SN - 1083-8155, 1083-8155 KW - Environment Abstracts; Sustainability Science Abstracts; Ecology Abstracts KW - Ecosystems KW - Urbanization KW - habitat changes KW - Landscape KW - Habitat KW - dispersal KW - spatial distribution KW - Conservation KW - vulnerability KW - Human factors KW - Dispersal KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - ENA 05:Environmental Design & Urban Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/860372208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Urban+Ecosystems&rft.atitle=Connectivity+in+urbanizing+landscapes%3A+The+importance+of+habitat+configuration%2C+urban+area+size%2C+and+dispersal&rft.au=Bierwagen%2C+Britta+G&rft.aulast=Bierwagen&rft.aufirst=Britta&rft.date=2007-03-01&rft.volume=10&rft.issue=1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Urban+Ecosystems&rft.issn=10838155&rft_id=info:doi/10.1007%2Fs11252-006-0011-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Urbanization; Landscape; Conservation; Dispersal; Habitat; spatial distribution; Ecosystems; habitat changes; vulnerability; Human factors; dispersal DO - http://dx.doi.org/10.1007/s11252-006-0011-6 ER - TY - JOUR T1 - Examining the Links between Biodiversity and Human Health: An Interdisciplinary Research Initiative at the U.S. Environmental Protection Agency AN - 754881668; 13410655 AB - Under the U.S. Environmental Protection Agency's mission to protect human health and the environment, the agency seeks to conduct research on the structure and function of ecosystems and to improve our understanding of the processes that contribute to the sustained health of the nation's ecosystems and the well-being of human populations. Changes in biodiversity can profoundly impact the ability of ecosystems to provide clean water, energy, food, recreation, and other services that contribute to human well-being. In addition, changes in biodiversity can affect the transmission of infectious disease to humans, particularly vectorborne diseases such as malaria and Lyme disease. The Environmental Protection Agency's new initiative supports interdisciplinary research to characterize the mechanisms that link biodiversity and human health and to use this knowledge to develop integrative tools and approaches for quantifying and predicting these relationships. Research on these links can have an important impact on our view of biodiversity and how we manage resources to protect human and ecosystem health. JF - EcoHealth AU - Pongsiri, Montira J AU - Roman, Joe AD - Office of Research and Development, National Center for Environmental Research, U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue NW, Mail Code 8723F, Washington, 20460, DC, pongsiri.montira@epa.gov Y1 - 2007/03// PY - 2007 DA - Mar 2007 SP - 82 EP - 85 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 4 IS - 1 SN - 1612-9202, 1612-9202 KW - Ecology Abstracts; Microbiology Abstracts B: Bacteriology; Sustainability Science Abstracts KW - interdisciplinary research KW - Ecosystems KW - Food KW - Biological diversity KW - Biodiversity KW - Malaria KW - Disease transmission KW - EPA KW - USA KW - Recreation KW - Infectious diseases KW - Structure-function relationships KW - malaria KW - Energy KW - Borrelia KW - human populations KW - Lyme disease KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754881668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=EcoHealth&rft.atitle=Examining+the+Links+between+Biodiversity+and+Human+Health%3A+An+Interdisciplinary+Research+Initiative+at+the+U.S.+Environmental+Protection+Agency&rft.au=Pongsiri%2C+Montira+J%3BRoman%2C+Joe&rft.aulast=Pongsiri&rft.aufirst=Montira&rft.date=2007-03-01&rft.volume=4&rft.issue=1&rft.spage=82&rft.isbn=&rft.btitle=&rft.title=EcoHealth&rft.issn=16129202&rft_id=info:doi/10.1007%2Fs10393-007-0087-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Recreation; Infectious diseases; Structure-function relationships; Food; Energy; Biodiversity; Malaria; Disease transmission; Lyme disease; EPA; interdisciplinary research; Ecosystems; malaria; Biological diversity; human populations; Borrelia; USA DO - http://dx.doi.org/10.1007/s10393-007-0087-3 ER - TY - JOUR T1 - Approaches to extrapolating animal toxicity data on organic solvents to public health. AN - 70577264; 16684563 AB - Synthesizing information about the acute neurotoxicity of organic solvents into predictive relationships between exposure and effect in humans is difficult because (1) data are usually derived from experimental animals whose sensitivity to the chemical relative to humans is unknown; (2) the specific endpoints measured in laboratory animals seldom translate into effects of concern in humans; and (3) the mode of action of the chemical is rarely understood. We sought to develop approaches to estimate the hazard and cost of exposure to organic solvents, focusing on the acute behavioral effects of toluene in rats and humans. Available published data include studies of shock avoidance behavior in rats and choice reaction time in humans. A meta-analysis of these data suggested that a 10% change in rat avoidance behavior occurs at a blood concentration of toluene 25 times higher than the concentration at which a 10% change in human choice reaction time occurs. In contrast, our in vitro studies of nicotinic acetylcholine receptors indicated that human and rat receptors do not differ in sensitivity to toluene. Analysis of other dose-response relationships for visual and cognitive functions in rats suggests that the apparent difference between rats and humans may be driven by the specific endpoints measured in the two species rather than by inherent differences in sensitivity to toluene. We also explored the hypothesis that dose-equivalence relationships may be used to compare the societal costs of two chemicals. For example, ethanol-induced changes in choice reaction time, for which societal costs are estimatable, may be used as a benchmark effect for estimating the monetary benefits of controlling exposure to organic solvents. This dose-equivalence method is applicable for solvents because this set of data fulfills three important assumptions about equivalence relationships based on a single effect: (1) a common dose metric (concentration of the chemical in the brain); (2) a common effect to provide a linking variable (choice reaction time); and (3) a common mode of action (interference with neuronal ion channel function). JF - Neurotoxicology AU - Bushnell, Philip J AU - Boyes, William K AU - Shafer, Timothy J AU - Bale, Ambuja S AU - Benignus, Vernon A AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. bushnell.philip@epa.gov Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 221 EP - 226 VL - 28 IS - 2 SN - 0161-813X, 0161-813X KW - Central Nervous System Depressants KW - 0 KW - Solvents KW - Toluene KW - 3FPU23BG52 KW - Ethanol KW - 3K9958V90M KW - Index Medicus KW - Animals KW - Reaction Time -- drug effects KW - Dose-Response Relationship, Drug KW - Humans KW - Avoidance Learning -- drug effects KW - Toluene -- toxicity KW - Risk Assessment KW - Cognition -- drug effects KW - Choice Behavior -- drug effects KW - Cost-Benefit Analysis KW - Ethanol -- toxicity KW - Meta-Analysis as Topic KW - Species Specificity KW - Visual Pathways -- drug effects KW - Behavior, Animal -- drug effects KW - Solvents -- toxicity KW - Central Nervous System Depressants -- toxicity KW - Neurotoxicity Syndromes -- economics KW - Toxicity Tests, Acute -- economics KW - Neurotoxicity Syndromes -- etiology KW - Central Nervous System -- drug effects KW - Public Health -- economics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70577264?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Approaches+to+extrapolating+animal+toxicity+data+on+organic+solvents+to+public+health.&rft.au=Bushnell%2C+Philip+J%3BBoyes%2C+William+K%3BShafer%2C+Timothy+J%3BBale%2C+Ambuja+S%3BBenignus%2C+Vernon+A&rft.aulast=Bushnell&rft.aufirst=Philip&rft.date=2007-03-01&rft.volume=28&rft.issue=2&rft.spage=221&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-08-21 N1 - Date created - 2007-06-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Ecological effects of density-independent mortality: application to cooling-water withdrawals. AN - 70475463; 17489247 AB - A wide variety of environmental stresses can cause density-independent mortality in species populations. One example is cooling-water withdrawals, which kill or injure many aquatic organisms near power plants and other industrial facilities. In the United States alone, hundreds of facilities withdraw trillions of gallons from inland and coastal waters every year to cool turbines and other manufacturing equipment. A number of detailed, site-specific studies of the effects of such cooling-water withdrawals have been conducted over the last 30 years, but only a few generalizations have been proposed in the peer-reviewed literature. In this paper we use a series of basic theoretical models to investigate the potential effects of density-independent mortality on species populations and ecosystems, with particular focus on the effects of cooling-water withdrawals on fish populations, fisheries, and aquatic communities. Among other results, we show that the effects of cooling-water withdrawals on a species will depend on the magnitude of other co-occurring stressors, environmental variability, the nature of the management regime in the associated fisheries, and the position of the species in the food web. The general models in this paper can provide a starting point for further empirical case studies and some preliminary conceptual guidance for decision makers who must choose between alternative policy options for controlling cooling-water withdrawals. JF - Ecological applications : a publication of the Ecological Society of America AU - Newbold, Stephen C AU - Iovanna, Rich AD - U.S. Environmental Protection Agency, National Center for Environmental Economics, Washington, D.C. 20046, USA. newbold.steve@epa.gov Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 390 EP - 406 VL - 17 IS - 2 SN - 1051-0761, 1051-0761 KW - Index Medicus KW - United States KW - Animals KW - Logistic Models KW - Population Dynamics KW - Fisheries -- economics KW - Environmental Monitoring -- methods KW - Conservation of Natural Resources KW - Rivers KW - Ecosystem KW - Industry -- methods KW - Models, Biological UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70475463?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+applications+%3A+a+publication+of+the+Ecological+Society+of+America&rft.atitle=Ecological+effects+of+density-independent+mortality%3A+application+to+cooling-water+withdrawals.&rft.au=Newbold%2C+Stephen+C%3BIovanna%2C+Rich&rft.aulast=Newbold&rft.aufirst=Stephen&rft.date=2007-03-01&rft.volume=17&rft.issue=2&rft.spage=390&rft.isbn=&rft.btitle=&rft.title=Ecological+applications+%3A+a+publication+of+the+Ecological+Society+of+America&rft.issn=10510761&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-06 N1 - Date created - 2007-05-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Differential sensitivity to anticholinesterase insecticides in the juvenile rat: effects on thermoregulation. AN - 70418636; 17454568 AB - Organophosphate (OP) and carbamate (CB) insecticides inhibit cholinesterase (ChE) activity and induce acute hypothermia in adult rats. Studies showed that juveniles are generally more susceptible to neurotoxic insult than adults. However, little is known concerning the effects of OP and CB pesticides on thermoregulation in developing animals. Thus, alterations in core body temperature (Tc) in juvenile animals exposed to an OP and CB insecticide were investigated. Male rat pups were anesthetized on postnatal day (PND) 15 with metofane and a radio transmitter (Data Sciences) was implanted in the abdominal cavity to monitor Tc and motor activity (MA). Two days were allowed for recovery. The PND 17 pups were then dosed by oral gavage with the OP chlorpyrifos (CHP) (1, 5, 10, or 15 mg/kg) or the CB carbaryl (CAR) (10, 20, 80, 120, or 160 mg/kg) or the corn oil vehicle. Pups were returned to their dams and littermates immediately after dosing and monitored for the next several days. CHP doses of 10 and 15 mg/kg resulted in 1.0 degrees C and 2.4 degrees C reductions in Tc, respectively. Tc recovered to control levels by approximately 16 h after dosing. There was significant mortality in rats dosed with 15 mg/kg CHP (6 of 11). CAR doses of 10 to 80 mg/kg had little effect on Tc. The highest dose of CAR (160 mg/kg) resulted in a 1.3 degrees C reduction in Tc that recovered in 9 h. In contrast, past studies found that adult male rats become hypothermic at CHP doses of >25 mg/kg, whereas a CAR dose of 50 mg/kg is effective at inducing hypothermia. Overall, it appears that during the development from preweanling to adult rat, there is a progressive attenuation in CHP-induced hypothermia. Conversely, CAR-induced hypothermia increases as a function of development. JF - Journal of toxicology and environmental health. Part A AU - Mack, Cina M AU - Gordon, Christopher J AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. mack.cina@epa.gov Y1 - 2007/03/01/ PY - 2007 DA - 2007 Mar 01 SP - 439 EP - 444 VL - 70 IS - 5 SN - 1528-7394, 1528-7394 KW - Cholinesterase Inhibitors KW - 0 KW - Insecticides KW - Chlorpyrifos KW - JCS58I644W KW - Carbaryl KW - R890C8J3N1 KW - Index Medicus KW - Rats KW - Animals, Newborn KW - Animals KW - Analysis of Variance KW - Rats, Long-Evans KW - Male KW - Insecticides -- toxicity KW - Body Temperature Regulation -- drug effects KW - Cholinesterase Inhibitors -- administration & dosage KW - Cholinesterase Inhibitors -- toxicity KW - Chlorpyrifos -- administration & dosage KW - Chlorpyrifos -- toxicity KW - Insecticides -- administration & dosage KW - Carbaryl -- toxicity KW - Carbaryl -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70418636?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Differential+sensitivity+to+anticholinesterase+insecticides+in+the+juvenile+rat%3A+effects+on+thermoregulation.&rft.au=Mack%2C+Cina+M%3BGordon%2C+Christopher+J&rft.aulast=Mack&rft.aufirst=Cina&rft.date=2007-03-01&rft.volume=70&rft.issue=5&rft.spage=439&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-15 N1 - Date created - 2007-04-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Neurosensory effects of chronic human exposure to arsenic associated with body burden and environmental measures. AN - 70396314; 17439919 AB - Exposure to arsenic in drinking water is known to produce a variety of health problems, including peripheral neuropathy. Auditory, visual and somatosensory impairment have been reported in Mongolian farmers living in the Yellow River Valley, where drinking water is contaminated by arsenic. In the present study, sensory tests, including pinprick and vibration thresholds, were administered to 320 residents with well-water arsenic levels, ranging from non-detectable to 690 microg/L. Vibration thresholds in the second and fifth fingers of both hands were measured using a vibrothesiometer. Drinking water, urine and toenail samples were obtained to assess arsenic exposure and body burden. Regression analyses indicated significant associations of pinprick scores and vibration thresholds with all arsenic measures. Vibration thresholds were more strongly associated with urinary than water or nail arsenic measures, but odds ratios for decreased pinprick sensitivity were highest for the water arsenic measure. Results of the current study indicate neurosensory effects of arsenic exposure at concentrations well below the 1000 microg/L drinking water level specified by NRC, and suggest that non-carcinogenic end-points, such as vibration thresholds, are useful in the risk assessment of exposure to arsenic in drinking water. JF - Human & experimental toxicology AU - Otto, D AU - Xia, Y AU - Li, Y AU - Wu, K AU - He, L AU - Telech, J AU - Hundell, H AU - Prah, J AU - Mumford, J AU - Wade, T AD - Human Studies Division, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. otto.david@epa.gov Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 169 EP - 177 VL - 26 IS - 3 SN - 0960-3271, 0960-3271 KW - Water Pollutants, Chemical KW - 0 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Body Burden KW - Humans KW - Child KW - Mongolia -- epidemiology KW - Environmental Monitoring KW - Water Supply -- analysis KW - Vibration KW - Adult KW - Neurologic Examination -- drug effects KW - Epidemiological Monitoring KW - Middle Aged KW - Nails -- chemistry KW - Adolescent KW - Environmental Exposure -- adverse effects KW - Female KW - Male KW - Arsenic -- analysis KW - Nervous System Diseases -- epidemiology KW - Arsenic -- toxicity KW - Water Pollutants, Chemical -- analysis KW - Water Pollutants, Chemical -- toxicity KW - Water Pollutants, Chemical -- urine KW - Nervous System Diseases -- chemically induced KW - Nervous System Diseases -- diagnosis KW - Arsenic -- urine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70396314?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+%26+experimental+toxicology&rft.atitle=Neurosensory+effects+of+chronic+human+exposure+to+arsenic+associated+with+body+burden+and+environmental+measures.&rft.au=Otto%2C+D%3BXia%2C+Y%3BLi%2C+Y%3BWu%2C+K%3BHe%2C+L%3BTelech%2C+J%3BHundell%2C+H%3BPrah%2C+J%3BMumford%2C+J%3BWade%2C+T&rft.aulast=Otto&rft.aufirst=D&rft.date=2007-03-01&rft.volume=26&rft.issue=3&rft.spage=169&rft.isbn=&rft.btitle=&rft.title=Human+%26+experimental+toxicology&rft.issn=09603271&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-18 N1 - Date created - 2007-04-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Estimating risk from ambient concentrations of acrolein across the United States. AN - 70379245; 17431491 AB - Estimated ambient concentrations of acrolein, a hazardous air pollutant, are greater than the U.S. Environmental Protection Agency (EPA) reference concentration throughout the United States, making it a concern for human health. However, there is no method for assessing the extent of risk under the U.S. EPA noncancer risk assessment framework. We estimated excess risks from ambient concentrations of acrolein based on dose-response modeling of a study in rats with a relationship between acrolein and residual volume/total lung capacity ratio (RV/TLC) and specific compliance (sC(L)), markers for altered lung function. Based on existing literature, we defined values above the 90th percentile for controls as "adverse." We estimated the increase over baseline response that would occur in the human population from estimated ambient concentrations of acrolein, taken from the U.S. EPA's National-Scale Air Toxics Assessment for 1999, after standard animal-to-human conversions and extrapolating to doses below the experimental data. The estimated median additional number of adverse sC(L) outcomes across the United States was approximately 2.5 cases per 1,000 people. The estimated range of additional outcomes from the 5th to the 95th percentile of acrolein concentration levels across census tracts was 0.28-14 cases per 1,000. For RV/TLC, the median additional outcome was 0.002 per 1,000, and the additional outcome at the 95th percentile was 0.13 per 1,000. Although there are uncertainties in estimating human risks from animal data, this analysis demonstrates a method for estimating health risks for noncancer effects and suggests that acrolein could be associated with decreased respiratory function in the United States. JF - Environmental health perspectives AU - Woodruff, Tracey J AU - Wells, Ellen M AU - Holt, Elizabeth W AU - Burgin, Deborah E AU - Axelrad, Daniel A AD - Office of Policy, Economics and Innovation, U.S. Environmental Protection Agency, San Francisco, California 94118, USA. tracey.woodruff@ucsf.edu Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 410 EP - 415 VL - 115 IS - 3 SN - 0091-6765, 0091-6765 KW - Air Pollutants KW - 0 KW - Acrolein KW - 7864XYD3JJ KW - Index Medicus KW - United States KW - Rats KW - Animals KW - Dose-Response Relationship, Drug KW - Humans KW - Residual Volume -- drug effects KW - Lung Compliance -- drug effects KW - Risk Assessment KW - Lung -- drug effects KW - Environmental Exposure -- adverse effects KW - Air Pollutants -- toxicity KW - Models, Biological KW - Lung -- physiology KW - Acrolein -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70379245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Estimating+risk+from+ambient+concentrations+of+acrolein+across+the+United+States.&rft.au=Woodruff%2C+Tracey+J%3BWells%2C+Ellen+M%3BHolt%2C+Elizabeth+W%3BBurgin%2C+Deborah+E%3BAxelrad%2C+Daniel+A&rft.aulast=Woodruff&rft.aufirst=Tracey&rft.date=2007-03-01&rft.volume=115&rft.issue=3&rft.spage=410&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-14 N1 - Date created - 2007-04-13 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Expo Anal Environ Epidemiol. 2001 May-Jun;11(3):231-52 [11477521] Environ Res. 2000 Mar;82(3):194-206 [10702327] Environ Health Perspect. 2002 Aug;110 Suppl 4:505-26 [12194881] Environ Health Perspect. 2002 Aug;110 Suppl 4:527-37 [12194882] Am J Physiol Lung Cell Mol Physiol. 2003 Oct;285(4):L931-9 [12832283] J Environ Manage. 2004 Nov;73(2):131-45 [15380318] Toxicol Appl Pharmacol. 1970 Nov;17(3):726-32 [4993037] Cancer Res. 1976 Sep;36(9 pt.1):2973-9 [975067] Int Arch Occup Environ Health. 1977 Nov 9;40(2):117-30 [591072] Toxicology. 1978 Feb;9(1-2):47-57 [653741] Clin Obstet Gynaecol. 1982 Dec;9(3):517-37 [6756748] Toxicology. 1984 May 1;31(1):53-65 [6729836] Toxicology. 1985 Feb;34(2):139-51 [3969686] Am Rev Respir Dis. 1986 Feb;133(2):286-91 [3946923] Toxicol Lett. 1987 Dec;39(2-3):189-98 [3686549] J Appl Physiol (1985). 1989 Jan;66(1):171-8 [2917919] J Appl Physiol (1985). 1989 Sep;67(3):1001-6 [2793693] Neurotoxicology. 1990 Summer;11(2):211-8 [1700346] Free Radic Biol Med. 1991;11(1):81-128 [1937131] Am J Respir Crit Care Med. 1994 Feb;149(2 Pt 1):382-6 [8306034] Regul Toxicol Pharmacol. 1995 Aug;22(1):24-9 [7494899] Fundam Appl Toxicol. 1996 Feb;29(2):208-18 [8742318] Toxicol Appl Pharmacol. 1997 Aug;145(2):331-9 [9266806] Toxicol Ind Health. 1998 May-Jun;14(3):429-54 [9569448] Environ Health Perspect. 1998 May;106(5):245-51 [9518474] Am J Physiol. 1999 Apr;276(4 Pt 1):L549-55 [10198352] J Am Med Assoc. 1957 Dec 14;165(15):1908-13 [13480837] Risk Anal. 2005 Apr;25(2):285-9 [15876204] Clin Sci (Lond). 2005 Jun;108(6):463-77 [15896192] J Expo Sci Environ Epidemiol. 2007 Jan;17(1):95-105 [17006436] J Air Waste Manag Assoc. 1999 Oct;49(10):1138-52 [10616743] Am J Physiol Lung Cell Mol Physiol. 2001 Sep;281(3):L732-9 [11504702] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Waterborne pathogens in urban watersheds. AN - 70335170; 17402286 AB - A serious concern for managers of water resources, pathogens in the urban environment easily enter waters through a number of pathways, including discharge of inadequately treated sewage, stormwater runoff, combined sewer overflows and sanitary sewer overflows. Pathogens in US ambient water bodies are regulated under the Clean Water Act (CWA), while pathogens in drinking water supplies are regulated under the Safe Drinking Water Act. Total maximum daily loads (TMDLs) are developed in accordance with CWA regulations for ambient water bodies with bacterial concentrations exceeding the water quality standard, which generally is a measure of a bacterial indicator organism. However, developing a TMDL for a supplementary indicator or pathogen is also required if a use impairment would still exist even after the water body is in compliance with the standard. This occurs because indicator organisms do not reflect the presence of pathogen contamination with complete certainty. The evaluation of pathogen indicators and summary of epidemiological studies presented are resources for those developing TMDLs to achieve water quality standards and restore water bodies to their intended uses. JF - Journal of water and health AU - Arnone, Russell D AU - Walling, Joyce Perdek AD - USEPA Region 2, Division of Science and Assessment, Edison, NJ 08837, USA. arnone.russell@epa.gov Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 149 EP - 162 VL - 5 IS - 1 SN - 1477-8920, 1477-8920 KW - Index Medicus KW - Protozoan Infections -- transmission KW - Environmental Monitoring KW - Virus Diseases -- transmission KW - Water Pollution -- legislation & jurisprudence KW - Humans KW - Water Supply KW - Epidemiological Monitoring KW - Disease Outbreaks KW - Urban Population KW - Gastroenteritis -- epidemiology KW - Bacterial Infections -- transmission KW - Fresh Water -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70335170?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+water+and+health&rft.atitle=Waterborne+pathogens+in+urban+watersheds.&rft.au=Arnone%2C+Russell+D%3BWalling%2C+Joyce+Perdek&rft.aulast=Arnone&rft.aufirst=Russell&rft.date=2007-03-01&rft.volume=5&rft.issue=1&rft.spage=149&rft.isbn=&rft.btitle=&rft.title=Journal+of+water+and+health&rft.issn=14778920&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-04-25 N1 - Date created - 2007-04-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A general indication of the Contemporary background levels of PCDDs, PCDFs, and coplanar PCBs in the ambient air over rural and remote areas of the United States. AN - 70328023; 17396638 AB - Long-term measurements of the atmospheric concentrations of PCDDs, PCDFs, and coplanar PCBs were taken in rural and remote areas of the United States by the National Dioxin Air Monitoring Network (NDAMN). A total of 21 quarterly sampling moments occurred from June, 1998 to December, 2002 at 34 locations geographically distributed throughout the United States. Sampling sites were located in rural and remote areas to obtain background air concentrations of dioxin-like compounds. Results were reported as the toxic equivalent (TEQ) of the mix of PCDDs/ PCDFs (TEQDF) and the mix of coplanar PCBs (TEQPCB). At the studied rural sites the mean annual TEQDF for each of the NDAMN sampling years was 10.43, 11.39, 10.40, and 10.47 fg m(-3) for 1999, 2000, 2001, and 2002, respectively. There was no statistically significant difference in the rural mean TEQDF air concentrations across the sampling years (at 0.05 level of significance), although the mean concentration in sampling year 2000 increased 10% relative to the other sampling years. The 95th percent confidence interval of TEQDF air concentrations in rural areas of the United States is from 6.4 to 15.4 fg m(-3), indicating there is a 95% probability that the true mean falls within this range. Mean annual atmospheric concentrations (TEQDF) at the remote sites were 1.41, 0.99, 0.7, and 1.07 fg m(-3) in 1999, 2000, 2001, and 2002, respectively, The 95th percent confidence interval of TEQDF air concentrations suggest that the true mean annual atmospheric TEQDF concentration in remote areas of the United States is between 0.1 and 3 fg m(-3). The remote sites have average air TEQDF concentrations that are approximately 10 times lower than those of the rural sites. For the rural sites, there was close agreement in the mean annual air concentrations of coplanar PCBs (TEQPCB) among the years 1999, 2000, 2001, and 2002 (i.e., 0.62, 0.69, 0.59, and 0.7 fg m(-3), respectively). However, as is the case with PCDDs/PCDFs, there was a marked increase (i.e., approximately equal to 13%) in the annual rural mean air concentration in 2000 as compared to the other sampling years. The confidence intervals across the NDAMN sampling years suggests a 95% probability that mean TEQPcB atmospheric concentrations in rural and remote areas of the United States are within the range of 0.5-0.9 fg m(-3) and 0.1-0.5 fg m(-3), respectively. The congener distributional patterns of PCDDs/PCDFs in air were relatively constant at all locations, and match the profile of urban air. We propose the hypothesis that urban areas are regional sources of PCDDs/PCDFs and are affecting atmospheric levels in rural and remote areas of the United States. JF - Environmental science & technology AU - Cleverly, David AU - Ferrario, Joseph AU - Byrne, Christian AU - Riggs, Karen AU - Joseph, Darrell AU - Hartford, Pamela AD - National Center for Environmental Assessment (8623N), Office of Research and Development, United States Environmental Protection Agency, Washington, DC, 20460, USA. cleverly.david@epa.gov Y1 - 2007/03/01/ PY - 2007 DA - 2007 Mar 01 SP - 1537 EP - 1544 VL - 41 IS - 5 SN - 0013-936X, 0013-936X KW - Air Pollutants KW - 0 KW - Benzofurans KW - Dibenzofurans, Polychlorinated KW - Polychlorinated Dibenzodioxins KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - United States KW - Polychlorinated Dibenzodioxins -- analogs & derivatives KW - Polychlorinated Dibenzodioxins -- analysis KW - Polychlorinated Biphenyls -- analysis KW - Air Pollutants -- analysis KW - Benzofurans -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70328023?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=A+general+indication+of+the+Contemporary+background+levels+of+PCDDs%2C+PCDFs%2C+and+coplanar+PCBs+in+the+ambient+air+over+rural+and+remote+areas+of+the+United+States.&rft.au=Cleverly%2C+David%3BFerrario%2C+Joseph%3BByrne%2C+Christian%3BRiggs%2C+Karen%3BJoseph%2C+Darrell%3BHartford%2C+Pamela&rft.aulast=Cleverly&rft.aufirst=David&rft.date=2007-03-01&rft.volume=41&rft.issue=5&rft.spage=1537&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-09 N1 - Date created - 2007-04-02 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Environ Sci Technol. 2007 Mar 1;41(5):1506-7 [17396628] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of prenatal chlordecone on sexually differentiated behavior in adult rats. AN - 70283355; 17169529 AB - In rodents, exposure to estrogens during early development masculinizes the structure and function of the brain. The effects of early exposure to estrogens or estrogenic compounds can be evaluated by neurobehavioral testing after puberty. In this study, the effect of developmental exposure to the chlorinated pesticide, chlordecone (CD) on sexually differentiated behaviors in adults was investigated because CD binds to estrogen receptors and causes estrogenic effects in the reproductive tract of humans and rodents at relatively high doses. Pregnant Sprague-Dawley rats were exposed to 5 mg/kg CD by intraperitoneal injection on gestation day 16 (GD 16). Offspring were gonadectomized on postnatal day 50 (PN 50) to remove the effects of circulating hormones and were sequentially tested for sex-typic spontaneous behaviors in an open field and elevated plus maze, and for male and female mating behavior following the appropriate steroid regimen. Female rats exposed in utero to CD showed an increased ratio of inner to total crossings in the open field and significantly increased lordosis and male mounting as compared to female control rats. Male rats exposed in utero to CD showed significantly increased lordosis as compared to male control rats and no change in male mating behaviors. Permanent changes in adult behavior were consistent with both estrogenic and anti-estrogenic actions following developmental exposure to CD at the dose tested. JF - Neurotoxicology and teratology AU - Laessig, Susan A AU - Auger, Anthony P AU - McCarthy, Margaret M AU - Silbergeld, Ellen K AD - Program in Toxicology, University of Maryland Medical System, Baltimore, MD 21201 USA. Laessig.susan@epa.gov PY - 2007 SP - 255 EP - 263 VL - 29 IS - 2 SN - 0892-0362, 0892-0362 KW - Insecticides KW - 0 KW - Testosterone KW - 3XMK78S47O KW - Chlordecone KW - RG5XJ88UDF KW - Index Medicus KW - Animals KW - Analysis of Variance KW - Maze Learning -- drug effects KW - Sex Factors KW - Pregnancy KW - Rats KW - Sexual Behavior, Animal -- drug effects KW - Rats, Sprague-Dawley KW - Exploratory Behavior -- drug effects KW - Testosterone -- blood KW - Motor Activity -- drug effects KW - Female KW - Male KW - Insecticides -- toxicity KW - Behavior, Animal -- drug effects KW - Sex Characteristics KW - Chlordecone -- toxicity KW - Prenatal Exposure Delayed Effects -- physiopathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70283355?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+teratology&rft.atitle=Effects+of+prenatal+chlordecone+on+sexually+differentiated+behavior+in+adult+rats.&rft.au=Laessig%2C+Susan+A%3BAuger%2C+Anthony+P%3BMcCarthy%2C+Margaret+M%3BSilbergeld%2C+Ellen+K&rft.aulast=Laessig&rft.aufirst=Susan&rft.date=2007-03-01&rft.volume=29&rft.issue=2&rft.spage=255&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+teratology&rft.issn=08920362&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-01 N1 - Date created - 2007-03-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Repeated inhalation of toluene by rats performing a signal detection task leads to behavioral tolerance on some performance measures. AN - 70282874; 17175136 AB - Previous work showed that trichloroethylene (TCE) impairs sustained attention as evidenced by a reduction in accuracy and elevation of response latencies in rats trained to perform a visual signal detection task (SDT). This work also showed that these effects abate during repeated exposures if rats inhale TCE while performing the SDT. The present experiment sought to determine whether toluene, another commonly-used solvent, would induce tolerance similarly if inhaled repeatedly during SDT testing. Sixteen male, Long-Evans rats were trained to perform the SDT. Upon completion of training, rats were divided into 2 groups. In Phase I, concentration-effect functions were determined for toluene (0, 1200, 1600, 2000, 2400 ppm) in both groups. Toluene reduced the proportion of correct responses [P(correct)], and increased response time (RT) and response failures. In Phase II, Group-Tol inhaled 1600 ppm toluene while Group-Air inhaled clean air during 11 daily SDT sessions. In Group-Tol the effect of toluene on P(correct) abated after 3 days, while RT remained elevated for the duration of the repeated exposures. In Phase III, toluene concentration-effect functions were re-determined for both groups. Group-Air remained impaired on all test measures, whereas for Group-Tol, toluene did not reduce P(correct), but continued to increase RT. These data confirm our previous hypothesis that animals can develop tolerance to chemical exposures that impair appetitively-motivated behaviors if that impairment leads to loss of reinforcement. JF - Neurotoxicology and teratology AU - Oshiro, Wendy M AU - Krantz, Q Todd AU - Bushnell, Philip J AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. PY - 2007 SP - 247 EP - 254 VL - 29 IS - 2 SN - 0892-0362, 0892-0362 KW - Solvents KW - 0 KW - Toluene KW - 3FPU23BG52 KW - Index Medicus KW - Rats KW - Reaction Time -- drug effects KW - Drug Tolerance KW - Behavior, Animal -- drug effects KW - Animals KW - Drug Administration Schedule KW - Analysis of Variance KW - Rats, Long-Evans KW - Dose-Response Relationship, Drug KW - Administration, Inhalation KW - Male KW - Conditioning, Operant -- drug effects KW - Toluene -- pharmacology KW - Signal Detection, Psychological -- drug effects KW - Solvents -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70282874?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+teratology&rft.atitle=Repeated+inhalation+of+toluene+by+rats+performing+a+signal+detection+task+leads+to+behavioral+tolerance+on+some+performance+measures.&rft.au=Oshiro%2C+Wendy+M%3BKrantz%2C+Q+Todd%3BBushnell%2C+Philip+J&rft.aulast=Oshiro&rft.aufirst=Wendy&rft.date=2007-03-01&rft.volume=29&rft.issue=2&rft.spage=247&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+teratology&rft.issn=08920362&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-01 N1 - Date created - 2007-03-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Cardiovascular effects of oral toluene exposure in the rat monitored by radiotelemetry. AN - 70280517; 17140765 AB - Toluene is a hazardous air pollutant that can be toxic to the nervous and cardiovascular systems. The cardiotoxicity data for toluene come from acute studies in anesthetized animals and from clinical observations made on toluene abusers and there is little known on the response of the cardiovascular and other autonomic processes to graded doses of toluene. This study assessed the effects of toluene (0.4, 0.8, and 1.2 g/kg; gavage) on heart rate (HR), blood pressure, core temperature (Tc), and motor activity (MA) in unrestrained, male Long-Evans rats monitored by telemetry. Toluene doses of 0.8 and 1.2 g/kg elicited significant elevations in HR, characterized by a transient 100 beats/min increase in HR lasting 1 h followed with a steady state tachycardia lasting >6 h. Overall, HR increased by 25 and 50 beats/min in the 0.8 and 1.2 g/kg groups, respectively. MA increased markedly in the 0.8 and 1.2 g/kg groups but the tachycardia persisted in spite of recovery of MA in the 0.8 g/kg group. There was a small (<0.5 degrees C) increase in Tc above controls in rats dosed with 0.8 g/kg toluene, whereas 1.2 g/kg toluene elicited a transient reduction in Tc followed by a small elevation lasting several hours. In a second study, rats were implanted with transmitters to monitor blood pressure (BP), and were administered with toluene as in the first study. HR, Tc, and MA were also monitored. The tachycardic effects of toluene at 0.8 and 1.2 g/kg were associated with a rise in blood pressure. Doses of 0.8 and 1.2 g/kg elicited a mean BP elevation of 6 and 16 mm Hg, respectively, for 7-hour post-dosing. The biphasic tachycardia to toluene suggests multiple sites for eliciting the cardiotoxic effects of this toxicant. JF - Neurotoxicology and teratology AU - Gordon, Christopher J AU - Samsam, Tracey E AU - Oshiro, Wendy M AU - Bushnell, Philip J AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. gordon.christopher@epa.gov PY - 2007 SP - 228 EP - 235 VL - 29 IS - 2 SN - 0892-0362, 0892-0362 KW - Solvents KW - 0 KW - Toluene KW - 3FPU23BG52 KW - Index Medicus KW - Rats KW - Administration, Oral KW - Animals KW - Heart Rate -- drug effects KW - Analysis of Variance KW - Rats, Long-Evans KW - Circadian Rhythm KW - Dose-Response Relationship, Drug KW - Telemetry -- methods KW - Motor Activity -- drug effects KW - Blood Pressure -- drug effects KW - Male KW - Toluene -- pharmacology KW - Cardiovascular System -- drug effects KW - Solvents -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70280517?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+teratology&rft.atitle=Cardiovascular+effects+of+oral+toluene+exposure+in+the+rat+monitored+by+radiotelemetry.&rft.au=Gordon%2C+Christopher+J%3BSamsam%2C+Tracey+E%3BOshiro%2C+Wendy+M%3BBushnell%2C+Philip+J&rft.aulast=Gordon&rft.aufirst=Christopher&rft.date=2007-03-01&rft.volume=29&rft.issue=2&rft.spage=228&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+teratology&rft.issn=08920362&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-01 N1 - Date created - 2007-03-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Interactive effects of solar UV radiation and climate change on biogeochemical cycling. AN - 70239904; 17344963 AB - This report assesses research on the interactions of UV radiation (280-400 nm) and global climate change with global biogeochemical cycles at the Earth's surface. The effects of UV-B (280-315 nm), which are dependent on the stratospheric ozone layer, on biogeochemical cycles are often linked to concurrent exposure to UV-A radiation (315-400 nm), which is influenced by global climate change. These interactions involving UV radiation (the combination of UV-B and UV-A) are central to the prediction and evaluation of future Earth environmental conditions. There is increasing evidence that elevated UV-B radiation has significant effects on the terrestrial biosphere with implications for the cycling of carbon, nitrogen and other elements. The cycling of carbon and inorganic nutrients such as nitrogen can be affected by UV-B-mediated changes in communities of soil organisms, probably due to the effects of UV-B radiation on plant root exudation and/or the chemistry of dead plant material falling to the soil. In arid environments direct photodegradation can play a major role in the decay of plant litter, and UV-B radiation is responsible for a significant part of this photodegradation. UV-B radiation strongly influences aquatic carbon, nitrogen, sulfur and metals cycling that affect a wide range of life processes. UV-B radiation changes the biological availability of dissolved organic matter to microorganisms, and accelerates its transformation into dissolved inorganic carbon and nitrogen, including carbon dioxide and ammonium. The coloured part of dissolved organic matter (CDOM) controls the penetration of UV radiation into water bodies, but CDOM is also photodegraded by solar UV radiation. Changes in CDOM influence the penetration of UV radiation into water bodies with major consequences for aquatic biogeochemical processes. Changes in aquatic primary productivity and decomposition due to climate-related changes in circulation and nutrient supply occur concurrently with exposure to increased UV-B radiation, and have synergistic effects on the penetration of light into aquatic ecosystems. Future changes in climate will enhance stratification of lakes and the ocean, which will intensify photodegradation of CDOM by UV radiation. The resultant increase in the transparency of water bodies may increase UV-B effects on aquatic biogeochemistry in the surface layer. Changing solar UV radiation and climate also interact to influence exchanges of trace gases, such as halocarbons (e.g., methyl bromide) which influence ozone depletion, and sulfur gases (e.g., dimethylsulfide) that oxidize to produce sulfate aerosols that cool the marine atmosphere. UV radiation affects the biological availability of iron, copper and other trace metals in aquatic environments thus potentially affecting metal toxicity and the growth of phytoplankton and other microorganisms that are involved in carbon and nitrogen cycling. Future changes in ecosystem distribution due to alterations in the physical and chemical climate interact with ozone-modulated changes in UV-B radiation. These interactions between the effects of climate change and UV-B radiation on biogeochemical cycles in terrestrial and aquatic systems may partially offset the beneficial effects of an ozone recovery. JF - Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology AU - Zepp, R G AU - Erickson, D J AU - Paul, N D AU - Sulzberger, B AD - U.S. Environmental Protection Agency, National Exposure Research Laboratory, 960 College Station Road, Athens, Georgia 30605-2700, USA. Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 286 EP - 300 VL - 6 IS - 3 SN - 1474-905X, 1474-905X KW - Metals KW - 0 KW - Carbon KW - 7440-44-0 KW - Index Medicus KW - Ecosystem KW - Animals KW - Oxidation-Reduction -- radiation effects KW - Ultraviolet Rays KW - Greenhouse Effect KW - Carbon -- metabolism KW - Metals -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70239904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Photochemical+%26+photobiological+sciences+%3A+Official+journal+of+the+European+Photochemistry+Association+and+the+European+Society+for+Photobiology&rft.atitle=Interactive+effects+of+solar+UV+radiation+and+climate+change+on+biogeochemical+cycling.&rft.au=Zepp%2C+R+G%3BErickson%2C+D+J%3BPaul%2C+N+D%3BSulzberger%2C+B&rft.aulast=Zepp&rft.aufirst=R&rft.date=2007-03-01&rft.volume=6&rft.issue=3&rft.spage=286&rft.isbn=&rft.btitle=&rft.title=Photochemical+%26+photobiological+sciences+%3A+Official+journal+of+the+European+Photochemistry+Association+and+the+European+Society+for+Photobiology&rft.issn=1474905X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-04 N1 - Date created - 2007-03-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Differentiation of Aeromonas isolated from drinking water distribution systems using matrix-assisted laser desorption/ionization-mass spectrometry. AN - 70221974; 17269751 AB - The genus Aeromonas is one of several medically significant genera that have gained prominence due to their evolving taxonomy and controversial role in human diseases. In this study, matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) was used to analyze the whole cells of both reference strains and unknown Aeromonas isolates obtained from water distribution systems. A library of over 45 unique m/z signatures was created from 40 strains that are representative of the 17 recognized species of Aeromonas, as well as 3 reference strains from genus Vibrio and 2 reference strains from Plesiomonas shigelloides. The library was used to help speciate 52 isolates of Aeromonas. The environmental isolates were broken up into 2 blind studies. Group 1 contained isolates that had a recognizable phenotypic profile and group 2 contained isolates that had an atypical phenotypic profile. MALDI-MS analysis of the water isolates in group 1 matched the phenotypic identification in all cases. In group 2, the MALDI-MS-based determination confirmed the identity of 18 of the 27 isolates. These results demonstrate that MALDI-MS analysis can rapidly and accurately classify species of the genus Aeromonas, making it a powerful tool especially suited for environmental monitoring and detection of microbial hazards in drinking water. JF - Analytical chemistry AU - Donohue, Maura J AU - Best, Jennifer M AU - Smallwood, Anthony W AU - Kostich, Mitchell AU - Rodgers, Mark AU - Shoemaker, Jody A AD - National Exposure Research Laboratory, Office of Ground Water and Drinking Water, National Council on the Aging, and National Risk Management Research Laboratory, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, USA. Donohue.maura@epa.gov Y1 - 2007/03/01/ PY - 2007 DA - 2007 Mar 01 SP - 1939 EP - 1946 VL - 79 IS - 5 SN - 0003-2700, 0003-2700 KW - Index Medicus KW - Vibrio -- classification KW - Phylogeny KW - Plesiomonas -- classification KW - Water Supply KW - Aeromonas -- isolation & purification KW - Bacterial Typing Techniques -- methods KW - Aeromonas -- classification KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization -- methods KW - Water Microbiology KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70221974?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Differentiation+of+Aeromonas+isolated+from+drinking+water+distribution+systems+using+matrix-assisted+laser+desorption%2Fionization-mass+spectrometry.&rft.au=Donohue%2C+Maura+J%3BBest%2C+Jennifer+M%3BSmallwood%2C+Anthony+W%3BKostich%2C+Mitchell%3BRodgers%2C+Mark%3BShoemaker%2C+Jody+A&rft.aulast=Donohue&rft.aufirst=Maura&rft.date=2007-03-01&rft.volume=79&rft.issue=5&rft.spage=1939&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=00032700&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-06-21 N1 - Date created - 2007-02-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur. AN - 70216615; 17197007 AB - To compare the toxicity of seven N-methyl carbamates, time course profiles for brain and red blood cell (RBC) cholinesterase (ChE) inhibition were established for each. Adult, male, Long Evans rats (n=4-5 dose group) were dosed orally with either carbaryl (30 mg/kg in corn oil); carbofuran (0.5 mg/kg in corn oil); formetanate HCl (10 mg/kg in water); methomyl (3 mg/kg in water); methiocarb (25 mg/kg in corn oil); oxamyl (1 mg/kg in water); or propoxur (20 mg/kg in corn oil). This level of dosing produced at least 40% brain ChE inhibition. Brain and blood were taken from 0.5 to 24 h after dosing for analysis of ChE activity using two different methods: (1) a radiometric method which limits the amount of reactivation of ChE activity, and (2) a spectrophotometric method (Ellman method using traditional, unmodified conditions) which may encourage reactivation. The time of peak ChE inhibition was similar for all seven N-methyl carbamate pesticides: 0.5-1.0 h after dosing. By 24 h, brain and RBC ChE activity in all animals returned to normal. The spectrophotometric method underestimated ChE inhibition. Moreover, there was a strong, direct correlation between brain and RBC ChE activity (radiometric assay) for all seven compounds combined (r(2)=0.73, slope 1.1), while the spectrophotometric analysis of the same samples showed a poor correlation (r(2)=0.09). For formetanate, propoxur, methomyl, and methiocarb, brain and RBC ChE inhibitions were not different over time, but for carbaryl, carbofuran and oxamyl, the RBC ChE was slightly more inhibited than brain ChE. These data indicate (1) the radiometric method is superior for analyses of ChE activity in tissues from carbamate-treated animals (2) that animals treated with these N-methyl carbamate pesticides are affected rapidly, and recover rapidly, and (3) generally, assessment of RBC ChE is an accurate predictor of brain ChE inhibition for these seven pesticides. JF - Toxicology and applied pharmacology AU - Padilla, S AU - Marshall, R S AU - Hunter, D L AU - Lowit, A AD - Cellular and Molecular Toxicology Branch, Neurotoxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Padilla.Stephanie@epa.gov Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 202 EP - 209 VL - 219 IS - 2-3 SN - 0041-008X, 0041-008X KW - Carbamates KW - 0 KW - Cholinesterase Inhibitors KW - Pesticides KW - Cholinesterases KW - EC 3.1.1.8 KW - Index Medicus KW - Rats KW - Molecular Structure KW - Cholinesterases -- metabolism KW - Brain -- enzymology KW - Animals KW - Rats, Long-Evans KW - Cholinesterases -- blood KW - Brain -- drug effects KW - Toxicity Tests, Acute KW - Time Factors KW - Male KW - Pesticides -- chemistry KW - Carbamates -- chemistry KW - Cholinesterase Inhibitors -- toxicity KW - Cholinesterase Inhibitors -- chemistry KW - Pesticides -- toxicity KW - Carbamates -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70216615?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Time+course+of+cholinesterase+inhibition+in+adult+rats+treated+acutely+with+carbaryl%2C+carbofuran%2C+formetanate%2C+methomyl%2C+methiocarb%2C+oxamyl+or+propoxur.&rft.au=Padilla%2C+S%3BMarshall%2C+R+S%3BHunter%2C+D+L%3BLowit%2C+A&rft.aulast=Padilla&rft.aufirst=S&rft.date=2007-03-01&rft.volume=219&rft.issue=2-3&rft.spage=202&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-03-29 N1 - Date created - 2007-02-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Epigenetic processes and cancer risk assessment. AN - 68993637; 17147955 AB - The U.S. Environmental Protection Agency's Guidelines for Carcinogen Risk Assessment encourages the use of mechanistic data in the assessment of human cancer risk at low (environmental) exposure levels. The key events that define a particular mode of action for tumor formation have been concentrated to date more on mutational responses that are broadly the result of induced DNA damage and enhanced cell proliferation. While it is clear that these processes are important in terms of tumor induction, other modes that fall under the umbrella of epigenetic responses are increasingly being considered to play an important role in susceptibility to tumor induction by environmental chemicals and as significant modifiers of tumor responses. Alterations in gene expression, DNA repair, cell cycle control, genome stability and genome reprogramming could be the result of modification of DNA methylation and chromatin remodeling patterns as a consequence of exposure to environmental chemicals. These concepts are described and discussed. JF - Mutation research AU - Preston, R Julian AD - National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. preston.julian@epa.gov Y1 - 2007/03/01/ PY - 2007 DA - 2007 Mar 01 SP - 7 EP - 10 VL - 616 IS - 1-2 SN - 0027-5107, 0027-5107 KW - Carcinogens, Environmental KW - 0 KW - Index Medicus KW - Rats KW - Animals KW - DNA Methylation KW - Chromatin Assembly and Disassembly KW - Male KW - Female KW - Risk Assessment KW - Genomic Imprinting KW - Carcinogens, Environmental -- toxicity KW - Epigenesis, Genetic KW - Neoplasms -- genetics KW - Neoplasms -- etiology KW - Neoplasms -- embryology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68993637?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mutation+research&rft.atitle=Epigenetic+processes+and+cancer+risk+assessment.&rft.au=Preston%2C+R+Julian&rft.aulast=Preston&rft.aufirst=R&rft.date=2007-03-01&rft.volume=616&rft.issue=1-2&rft.spage=7&rft.isbn=&rft.btitle=&rft.title=Mutation+research&rft.issn=00275107&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-05-02 N1 - Date created - 2007-02-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Small-scale heterogeneity in the geochemistry of seagrass vegetated and non-vegetated estuarine sediments; causes and consequences AN - 51449476; 2007-042935 JF - Aquatic Geochemistry AU - Hebert, Andrew B AU - Morse, John W AU - Eldridge, Peter M Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 19 EP - 39 PB - Springer, Dordrecht VL - 13 IS - 1 SN - 1380-6165, 1380-6165 KW - United States KW - benthic taxa KW - sea water KW - biomass KW - bioavailability KW - vegetation KW - bioaccumulation KW - grasses KW - Oregon KW - Yaquina Bay KW - intertidal environment KW - sediments KW - Newport Oregon KW - Lincoln County Oregon KW - ecology KW - reduction KW - estuarine environment KW - geochemistry KW - productivity KW - seagrasses KW - sulfate ion KW - biochemistry KW - nearshore environment KW - nutrients KW - habitat KW - dissolved materials KW - coastal environment KW - sulfides KW - pore water KW - 02C:Geochemistry of rocks, soils, and sediments KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51449476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Geochemistry&rft.atitle=Small-scale+heterogeneity+in+the+geochemistry+of+seagrass+vegetated+and+non-vegetated+estuarine+sediments%3B+causes+and+consequences&rft.au=Hebert%2C+Andrew+B%3BMorse%2C+John+W%3BEldridge%2C+Peter+M&rft.aulast=Hebert&rft.aufirst=Andrew&rft.date=2007-03-01&rft.volume=13&rft.issue=1&rft.spage=19&rft.isbn=&rft.btitle=&rft.title=Aquatic+Geochemistry&rft.issn=13806165&rft_id=info:doi/10.1007%2Fs10498-006-9007-3 L2 - http://www.springerlink.com/app/home/journal.asp?wasp=06310259ce2e45a6a9eacb848fdddbe0&referrer=parent&backto=linkingpublicationresults,1:100238,1 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2007-01-01 N1 - Number of references - 38 N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - benthic taxa; bioaccumulation; bioavailability; biochemistry; biomass; coastal environment; dissolved materials; ecology; estuarine environment; geochemistry; grasses; habitat; intertidal environment; Lincoln County Oregon; nearshore environment; Newport Oregon; nutrients; Oregon; pore water; productivity; reduction; sea water; seagrasses; sediments; sulfate ion; sulfides; United States; vegetation; Yaquina Bay DO - http://dx.doi.org/10.1007/s10498-006-9007-3 ER - TY - JOUR T1 - Impact of ethanol on the natural attenuation of MTBE in a normally sulfate-reducing aquifer AN - 50514441; 2009-021242 JF - Environmental Science & Technology, ES & T AU - Mackay, Doug AU - De Sieyes, Nick AU - Einarson, Murray D AU - Feris, Kevin P AU - Pappas, Alex AU - Wood, Isaac AU - Jacobson, Lisa AU - Justice, Larry G AU - Noske, Mark N AU - Wilson, John AU - Adair, Cherri AU - Scow, Kate M Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 2015 EP - 2021 PB - American Chemical Society, Washington, DC VL - 41 IS - 6 SN - 0013-936X, 0013-936X KW - United States KW - aliphatic hydrocarbons KW - ground water KW - ethers KW - methyl tert-butyl ether KW - natural attenuation KW - alcohols KW - alkalinity KW - reduction KW - water pollution KW - geochemistry KW - pH KW - experimental studies KW - methane KW - sulfates KW - pollutants KW - pollution KW - alkanes KW - hydrochemistry KW - aquifers KW - nutrients KW - ethanol KW - organic compounds KW - hydrocarbons KW - anaerobic environment KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50514441?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology%2C+ES+%26+T&rft.atitle=Impact+of+ethanol+on+the+natural+attenuation+of+MTBE+in+a+normally+sulfate-reducing+aquifer&rft.au=Mackay%2C+Doug%3BDe+Sieyes%2C+Nick%3BEinarson%2C+Murray+D%3BFeris%2C+Kevin+P%3BPappas%2C+Alex%3BWood%2C+Isaac%3BJacobson%2C+Lisa%3BJustice%2C+Larry+G%3BNoske%2C+Mark+N%3BWilson%2C+John%3BAdair%2C+Cherri%3BScow%2C+Kate+M&rft.aulast=Mackay&rft.aufirst=Doug&rft.date=2007-03-01&rft.volume=41&rft.issue=6&rft.spage=2015&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology%2C+ES+%26+T&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes062156q L2 - http://pubs.acs.org/journals/esthag/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 12 N1 - PubXState - DC N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - CODEN - ESTHAG N1 - SubjectsTermNotLitGenreText - alcohols; aliphatic hydrocarbons; alkalinity; alkanes; anaerobic environment; aquifers; ethanol; ethers; experimental studies; geochemistry; ground water; hydrocarbons; hydrochemistry; methane; methyl tert-butyl ether; natural attenuation; nutrients; organic compounds; pH; pollutants; pollution; reduction; sulfates; United States; water pollution DO - http://dx.doi.org/10.1021/es062156q ER - TY - JOUR T1 - Mapping road-salt contaminated ground-water discharge in a watershed in southern New Hampshire AN - 50257325; 2008-095454 AB - The use of salt for road deicing has caused increases in chloride concentrations in ground- and surface-water resources. Concentrations of chloride in excess of water-quality standards have been measured in watersheds adjacent to interstate highway 93 (I-93) in southern New Hampshire (NH). A proposed widening plan for I-93 has raised concerns over potential increases in chloride. To formulate a load reduction plan, the NH Departments of Environmental Services and Transportation are working to identify sources of chloride and develop an understanding of chloride fate and transport in the hydrologic system, as part of a total maximum daily load study. As part of this effort, road-salt contaminated ground-water discharge was mapped in the fall of 2006 to identify potential sources of chloride during base-flow conditions in Policy Brook. This brook drains a small watershed (10.2 square miles) of mixed land use (wooded, residential, commercial, and highway) with multiple sources of salt contamination. The area is underlain by a thin (20 feet) surficial sand layer and basal till, which are underlain by fractured crystalline bedrock. Streamflow in Policy Brook ranged from 0.59 to 515 cubic feet per second from February to November of 2006. Measurements of specific conductance showed high levels (1.3 millimhos/centimeter (mmhos/cm)), about 5 times background, during periods of base flow, indicating a ground-water source of road salt. Electromagnetic (EM) terrain induction conductivity surveys were performed along the longitudinal axis of Policy Brook to facilitate mapping of road-salt contaminated ground-water discharge. Three different EM tools were used that probed slightly different depths below the streambed (ranging from 0 to 12 feet). Results from the three tools showed good agreement and identified several reaches where high conductivity ground water may have been discharging. EM conductivity values ranged from 10 (typical background value for sand) to 300 mmhos/meter in the streambed of Policy Brook. Based on the delineation of high EM values, seven streambed piezometers were installed to sample streambed pore water. Specific conductance in the pore water ranged from 0.64 to 26 mmhos/cm. Locations with high specific conductance in streambed pore water matched well with locations with high EM-conductivity values. JF - Abstracts with Programs - Geological Society of America AU - Harte, Philip T AU - Heath, Douglas AU - Belaval, Marcel AU - Corcoran, Kenneth AU - Trowbridge, Philip AU - Anonymous Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 58 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 1 SN - 0016-7592, 0016-7592 KW - United States KW - hydrology KW - aquifer vulnerability KW - concentration KW - road salt KW - pollutants KW - background level KW - surface water KW - regional planning KW - watersheds KW - pollution KW - mapping KW - southern New Hampshire KW - ground water KW - aquifers KW - New Hampshire KW - hydraulic conductivity KW - discharge KW - roads KW - pore water KW - land use KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50257325?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Mapping+road-salt+contaminated+ground-water+discharge+in+a+watershed+in+southern+New+Hampshire&rft.au=Harte%2C+Philip+T%3BHeath%2C+Douglas%3BBelaval%2C+Marcel%3BCorcoran%2C+Kenneth%3BTrowbridge%2C+Philip%3BAnonymous&rft.aulast=Harte&rft.aufirst=Philip&rft.date=2007-03-01&rft.volume=39&rft.issue=1&rft.spage=58&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, Northeastern Section, 42nd annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2008-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - aquifer vulnerability; aquifers; background level; concentration; discharge; ground water; hydraulic conductivity; hydrology; land use; mapping; New Hampshire; pollutants; pollution; pore water; regional planning; road salt; roads; southern New Hampshire; surface water; United States; watersheds ER - TY - JOUR T1 - A Tribute to Dr. William Penn Watkinson AN - 21042452; 8017323 AB - Abstract not available. JF - Inhalation Toxicology AU - Costa, Daniel L AD - Pulmonary Toxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA Y1 - 2007/03// PY - 2007 DA - Mar 2007 SP - 381 EP - 382 PB - Taylor & Francis, 325 Chestnut Street Suite 800 Philadelphia PA 19106 USA, [URL:http://www.taylorandfrancis.com/] VL - 19 IS - 5 SN - 0895-8378, 0895-8378 KW - Toxicology Abstracts KW - Inhalation KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21042452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inhalation+Toxicology&rft.atitle=A+Tribute+to+Dr.+William+Penn+Watkinson&rft.au=Costa%2C+Daniel+L&rft.aulast=Costa&rft.aufirst=Daniel&rft.date=2007-03-01&rft.volume=19&rft.issue=5&rft.spage=381&rft.isbn=&rft.btitle=&rft.title=Inhalation+Toxicology&rft.issn=08958378&rft_id=info:doi/10.1080%2F08958370701266027 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Inhalation DO - http://dx.doi.org/10.1080/08958370701266027 ER - TY - JOUR T1 - Using Ecological Risk Assessment Principles in a Source Water Protection Assessment AN - 20793292; 10310196 AB - It has become increasingly common to apply ecological risk assessment (ERA) principles to watershed and regional scale environmental management. This article describes the application of watershed ERA principles to the development of a source water protection assessment and a strategic watershed management plan. The primary focus was on the protection of drinking water quality, a concern typically addressed by human health risk assessors. The approach emphasizes adaptations to the problem formulation phase of ERA (defining assessment endpoints, developing conceptual models and an analysis plan) suitable for watershed management planning in a multi-objective, multi-stressor context. Physical, chemical, and biological attributes were selected for primary drinking water quality assessment endpoints, and coupled with additional assessment endpoints relevant to other environmental and social management objectives. Conceptual models helped the planning team to better understand and communicate the multiple natural and human stressors in the watershed and the causal pathways by which they affected drinking water. The article provides an example of the types of adaptations that can make ERA principles suitable for watershed management related to human health goals, and illustrates the efficiency of integrating health and ecological assessments. JF - Human and Ecological Risk Assessment AU - Serveiss, Victor AU - Ohlson, Dan AD - U.S. EPA, Washington, DC, USA Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 402 EP - 417 PB - Taylor & Francis Group Ltd., 2 Park Square Milton Park, Abingdon Oxford OX14 4RN UK VL - 13 IS - 2 SN - 1080-7039, 1080-7039 KW - Pollution Abstracts; Risk Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Risk assessment KW - Watershed Management KW - Freshwater KW - Watersheds KW - Water quality KW - Risks KW - adaptability KW - Public health KW - Efficiency KW - Drinking Water KW - water protection KW - Assessments KW - Planning KW - Adaptation KW - Watershed management KW - Regional planning KW - River basin management KW - Adaptations KW - Protection KW - Model Studies KW - Risk KW - Water management KW - Quality control KW - Drinking water KW - Environment management KW - National planning KW - P 2000:FRESHWATER POLLUTION KW - Q2 09181:General KW - SW 3060:Water treatment and distribution KW - R2 23050:Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20793292?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+and+Ecological+Risk+Assessment&rft.atitle=Using+Ecological+Risk+Assessment+Principles+in+a+Source+Water+Protection+Assessment&rft.au=Serveiss%2C+Victor%3BOhlson%2C+Dan&rft.aulast=Serveiss&rft.aufirst=Victor&rft.date=2007-03-01&rft.volume=13&rft.issue=2&rft.spage=402&rft.isbn=&rft.btitle=&rft.title=Human+and+Ecological+Risk+Assessment&rft.issn=10807039&rft_id=info:doi/10.1080%2F10807030701226822 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Adaptations; Water management; Regional planning; Water quality; Watersheds; River basin management; Risks; National planning; Public health; Risk assessment; Efficiency; water protection; Quality control; Watershed management; Drinking water; Environment management; adaptability; Risk; Drinking Water; Assessments; Planning; Adaptation; Watershed Management; Protection; Model Studies; Freshwater DO - http://dx.doi.org/10.1080/10807030701226822 ER - TY - JOUR T1 - Sediment-Associated Phototoxicity to Aquatic Organisms AN - 20792249; 10310190 AB - Phototoxicity is a two to greater than 1000-fold increase in chemical toxicity caused by ultraviolet radiation (UV), which has been demonstrated in a broad range of marine and freshwater fish, invertebrates, and other aquatic organisms in water column exposures. Field collected sediments containing polycyclic aromatic hydrocarbons (PAHs) and other contaminants are phototoxic to sediment-dwelling organisms in laboratory tests, but in situ or field investigations of phototoxicity have not been reported. Sediment provides a pathway for the bioaccumulation of phototoxic chemicals through contact with and ingestion of bedded and suspended sediment, and maternal transfer, but risks are uncertain. Risks from sediment-associated phototoxicity will be greatest in areas of both high contaminant exposure (e.g., surficial and suspended sediments in harbors, outfall areas, and spill sites), and high UV exposure (e.g., high optical clarity or shallow depths). Organisms and life-stages most at risk will be those translucent to UV that inhabit the photic zone and near shore areas, but benthic organisms may have generally low UV exposure because of life history and morphological characteristics. Site-specific assessments are needed to characterize risks both spatially and temporally because of heterogeneous sediment contamination and large differences in species sensitivity and exposure pathways. JF - Human and Ecological Risk Assessment AU - Barron, MacE AD - U.S. Environmental Protection Agency, GED/ORD, Gulf Breeze, FL, USA Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 317 EP - 321 PB - Taylor & Francis Group Ltd., 2 Park Square Milton Park, Abingdon Oxford OX14 4RN UK VL - 13 IS - 2 SN - 1080-7039, 1080-7039 KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Risk Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Risk assessment KW - shores KW - Aquatic organisms KW - Freshwater KW - Freshwater fish KW - Toxicity tests KW - Phototoxicity KW - Resuspended sediments KW - Assessments KW - Pollutants KW - Exposure KW - Ultraviolet radiation KW - Sediment Contamination KW - Aromatic hydrocarbons KW - Pollution indicators KW - Sensitivity KW - Sediment pollution KW - Sediment chemistry KW - Suspended Sediments KW - Polycyclic aromatic hydrocarbons KW - Laboratory testing KW - life history KW - Toxicity KW - Ingestion KW - Sediments KW - Outfalls KW - Risk KW - Bioaccumulation KW - Water Pollution Effects KW - water column KW - polycyclic aromatic hydrocarbons KW - Harbors KW - Q2 09271:Coastal morphology KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - R2 23050:Environment KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20792249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+and+Ecological+Risk+Assessment&rft.atitle=Sediment-Associated+Phototoxicity+to+Aquatic+Organisms&rft.au=Barron%2C+MacE&rft.aulast=Barron&rft.aufirst=MacE&rft.date=2007-03-01&rft.volume=13&rft.issue=2&rft.spage=317&rft.isbn=&rft.btitle=&rft.title=Human+and+Ecological+Risk+Assessment&rft.issn=10807039&rft_id=info:doi/10.1080%2F10807030701226285 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Resuspended sediments; Sediment chemistry; Sediment pollution; Bioaccumulation; Ultraviolet radiation; Aromatic hydrocarbons; Freshwater fish; Pollution indicators; Toxicity tests; shores; Risk assessment; Aquatic organisms; Sensitivity; Laboratory testing; life history; Ingestion; Sediments; Phototoxicity; Outfalls; polycyclic aromatic hydrocarbons; water column; Harbors; Risk; Polycyclic aromatic hydrocarbons; Suspended Sediments; Pollutants; Assessments; Water Pollution Effects; Exposure; Sediment Contamination; Toxicity; Freshwater DO - http://dx.doi.org/10.1080/10807030701226285 ER - TY - JOUR T1 - Elevated temperature, soil moisture and seasonality but not CO sub(2) affect canopy assimilation and system respiration in seedling Douglas-fir ecosystems AN - 20616685; 7393775 AB - We investigated the effects of elevated atmospheric CO sub(2) and air temperature on C cycling in trees and associated soil system, focusing on canopy CO sub(2) assimilation (A sub(sys)) and system CO sub(2) loss through respiration (R sub(sys)). We hypothesized that both elevated CO sub(2) and elevated temperature would stimulate A sub(sys) and R sub(sys). The study was conducted in sun-lit controlled-environment mesocosms using Douglas-fir (Pseudotsuga menziesii Mirb. Franco) seedlings grown in reconstructed plant- litter-soil systems. A completely randomized design with two atmospheric CO sub(2) and two air temperature levels was used. A mass-balance approach was used to calculate daily mean A sub(sys) and R sub(sys) rates for 19 months. A mixed model analysis was used to test the effects of CO sub(2) and air temperature on daily A sub(sys) and R sub(sys) adjusted for covariates of time, light, soil moisture and seasonality. Elevated temperature stimulated A sub(sys) and R sub(sys) but elevated CO sub(2) did not. Elevated CO sub(2) and temperature both increased light sensitivity and the light saturation level of photosynthesis. Both A sub(sys) and R sub(sys) were controlled by temperature, soil moisture and endogenous seasonal processes. Temperature sensitivity of R sub(sys) varied seasonally but there was no acclimatization. Because of the close linkage between assimilation and respiration, elevated CO sub(2) failed to stimulate A sub(sys) and R sub(sys). Although CO sub(2) is a substrate, assimilate is also controlled by its concentration. Needle-level studies established that increasing CO sub(2) down regulates assimilation through changes in Rubisco, especially if resources are limited. This study shows that increasing CO sub(2) also regulates assimilation allometrically through changes in needle area. Stimulation of assimilation is offset by a reduction in needle area such that the A sub(sys) and R sub(sys) are similar in ambient and elevated treatments. JF - Agricultural and Forest Meteorology AU - Tingey, David T AU - Phillips, Donald L AU - Lee, EHenry AU - Waschmann, Ronald S AU - Olszyk, David M AU - Rygiewicz, Paul T AU - Johnson, Mark G AD - U.S. Environmental Protection Agency, Western Ecology Division, 200 SW 35th Street, Corvallis, OR 97333, USA, phillips.donald@epa.gov Y1 - 2007/03// PY - 2007 DA - Mar 2007 SP - 30 EP - 48 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 143 IS - 1-2 SN - 0168-1923, 0168-1923 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Douglas-fir trees KW - Pseudotsuga menziesii KW - Carbon dioxide KW - Global warming KW - Photosynthesis KW - Respiration KW - air temperature KW - Ecosystems KW - Trees KW - Acclimatization KW - Temperature KW - Forests KW - Data assimilation KW - Soil KW - Sulfur dioxide KW - Forest canopy KW - Seedlings KW - Soil moisture KW - Seasonal variations KW - canopies KW - P 0000:AIR POLLUTION KW - M2 556.14:Infiltration/Soil Moisture (556.14) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20616685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Agricultural+and+Forest+Meteorology&rft.atitle=Elevated+temperature%2C+soil+moisture+and+seasonality+but+not+CO+sub%282%29+affect+canopy+assimilation+and+system+respiration+in+seedling+Douglas-fir+ecosystems&rft.au=Tingey%2C+David+T%3BPhillips%2C+Donald+L%3BLee%2C+EHenry%3BWaschmann%2C+Ronald+S%3BOlszyk%2C+David+M%3BRygiewicz%2C+Paul+T%3BJohnson%2C+Mark+G&rft.aulast=Tingey&rft.aufirst=David&rft.date=2007-03-01&rft.volume=143&rft.issue=1-2&rft.spage=30&rft.isbn=&rft.btitle=&rft.title=Agricultural+and+Forest+Meteorology&rft.issn=01681923&rft_id=info:doi/10.1016%2Fj.agrformet.2006.11.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-06-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Forest canopy; Ecosystems; Photosynthesis; Acclimatization; Soil moisture; Data assimilation; air temperature; Trees; Respiration; Temperature; Forests; Soil; Sulfur dioxide; Seedlings; Carbon dioxide; Seasonal variations; canopies; Pseudotsuga menziesii DO - http://dx.doi.org/10.1016/j.agrformet.2006.11.005 ER - TY - JOUR T1 - Diagnosis of trace Pb in domestic wells, Upper Gloucester Catchment, Maine, USA AN - 20391305; 7370359 AB - Dissolved Pb in 32 wells associated with corroding submersible pumps is examined within a rural water district after almost 20 years (1984-2002). Groundwater Pb ranged from 0.4-24.9 mu g L super(-1) after 24 h pump flushing. Preliminary geochemistry and representative borehole lithology examinations were extrapolated by Markov chain modeling. The first-order geostatistical realizations of glacial sediments coupled with the Monte Carlo Metropolis-Hasting method suggest that elevated trace Pb persists in sand and gravel units, and continues at least to 40 m depth in the catchment. The super(207)Pb/ super(206)Pb and super(208)Pb/ super(206)Pb isotope compositions of groundwater Pb were decisive in discriminating the importance of leached Pb from submersible pump materials among geogenic sources. JF - Environmental Geology AU - Sidle, W C AD - Water Supply and Water Resources Division, 26 West Martin Luther King Blvd., Cincinnati, OH, 45268, USA, sidle.william@epa.gov Y1 - 2007/03// PY - 2007 DA - Mar 2007 SP - 51 EP - 62 PB - Springer-Verlag (Berlin), Heidelberger Platz 3 Berlin 14197 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 52 IS - 1 SN - 0943-0105, 0943-0105 KW - Pollution Abstracts KW - Isotopes KW - Leaching KW - Geochemistry KW - Lead KW - Sediments KW - boreholes KW - Sand KW - Catchments KW - Water wells KW - USA, Maine KW - Pumps KW - lithology KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20391305?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Geology&rft.atitle=Diagnosis+of+trace+Pb+in+domestic+wells%2C+Upper+Gloucester+Catchment%2C+Maine%2C+USA&rft.au=Sidle%2C+W+C&rft.aulast=Sidle&rft.aufirst=W&rft.date=2007-03-01&rft.volume=52&rft.issue=1&rft.spage=51&rft.isbn=&rft.btitle=&rft.title=Environmental+Geology&rft.issn=09430105&rft_id=info:doi/10.1007%2Fs00254-006-0448-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Isotopes; boreholes; Leaching; Sand; Geochemistry; Catchments; Water wells; Pumps; lithology; Sediments; Lead; USA, Maine DO - http://dx.doi.org/10.1007/s00254-006-0448-1 ER - TY - JOUR T1 - Reliability of confocal microscopy spectral imaging systems: Use of multispectral beads AN - 20379541; 7760081 AB - Background: There is a need for a standardized, impartial calibration, and validation protocol on confocal spectral imaging (CSI) microscope systems. To achieve this goal, it is necessary to have testing tools to provide a reproducible way to evaluate instrument performance. Methods: We evaluated fluorescent spectral beads (FocalCheckTM) from Molecular Probes/Invitrogen that consist of four pairs with emissions between 500 and 725 nm and a europium macrocycle quantum dye bead. These bead tools compliment our previously published protocol for testing spectral imaging systems that used an inexpensive multi-ion discharge lamp (MIDL) that contains Hg+, Ar+, and inorganic fluorophores that emits distinct, stable spectral features. Results: We acquired the spectra of the FocalCheckTM beads on a Zeiss 510 Meta, a Leica TCS-SP1, a Leica SP2 AOBS, an Olympus FV 1000, and a Nikon C1Si confocal systems and a PARISS microscopic spectral system and of the europium beads on the Leica TCS-SP1 and PARISS spectral imaging systems. A lack of performance with some equipment between 650 and 750 nm was identified using the far red pair of the FocalCheckTM beads. The position of the slider in front of PMT 2 that reflects light into PMT 1 and PMT 3 affected the measurement of all bead intensities. Unmixing algorithms were used to separate beads with different fluorochromes and separate two fluorochromes on the same bead. Conclusions: The FocalCheckTM multi-spectral beads yielded similar profiles on four CSI systems and a PARISS spectral system. The utilization of the spectral FocalCheckTM beads is helpful to evaluate proper spectral performance, especially in the far red region. Europium beads provide a very narrow spectrum that can help to identify machines that have spectral problems. The dyes located on individual beads or mixed together in ring-core configuration can be used as test particles to demonstrate spectral unmixing with various algorithms. JF - Cytometry Part A AU - Zucker, Robert M AU - Rigby, Paul AU - Clements, Ian AU - Salmon, Wendy AU - Chua, Michael AD - Reproductive Toxicology Division (MD-67), National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, zucker.robert@.epa.gov Y1 - 2007/03// PY - 2007 DA - Mar 2007 SP - 174 EP - 189 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk], [URL:http://www.wiley.com/] VL - 71A IS - 3 SN - 1552-4922, 1552-4922 KW - Biotechnology and Bioengineering Abstracts KW - Dyes KW - Confocal microscopy KW - Algorithms KW - Fluorescent indicators KW - fluorophores KW - fluorochromes KW - imaging KW - Cytometry KW - Light effects KW - W 30910:Imaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20379541?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cytometry+Part+A&rft.atitle=Reliability+of+confocal+microscopy+spectral+imaging+systems%3A+Use+of+multispectral+beads&rft.au=Zucker%2C+Robert+M%3BRigby%2C+Paul%3BClements%2C+Ian%3BSalmon%2C+Wendy%3BChua%2C+Michael&rft.aulast=Zucker&rft.aufirst=Robert&rft.date=2007-03-01&rft.volume=71A&rft.issue=3&rft.spage=174&rft.isbn=&rft.btitle=&rft.title=Cytometry+Part+A&rft.issn=15524922&rft_id=info:doi/10.1002%2Fcyto.a.20371 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - imaging; fluorochromes; Algorithms; Fluorescent indicators; Confocal microscopy; Dyes; Light effects; Cytometry; fluorophores DO - http://dx.doi.org/10.1002/cyto.a.20371 ER - TY - JOUR T1 - Modeling coupling between eelgrass Zostera marina and water flow AN - 20355843; 7486906 AB - Ecological effects caused by submerged aquatic vegetation not only depend on the plants and their morphology but also on the flow and transport patterns of dissolved and suspended constituents near the canopy. Canopy height is a major variable in any quantitative analysis of plant biomass and constituent transport in its vicinity. Height of eelgrass Zostera marina canopies changes due to bending of the blades under varying current regimes. In this paper, I mathematically modeled the coupling between eelgrass blade bending and water flow. Based on the balance of forces of drag, lift, friction, weight and buoyancy on a single blade, the model defined the bending of blades (i.e. height of canopy) and the flow response within and above the canopy. This coupling was tested using laboratory data and indicated that the model performed adequately. Both model results and laboratory data confirmed that the bending of blades, and hence canopy height, was very sensitive to current magnitude and directly influenced current profile. Identifying canopy height is a major factor in defining spatial distribution of grass biomass from optical or acoustic remote sensing devices. The model has direct implications for biological issues related to the plants themselves and to their associated organisms, such as the vertical distribution of photosynthesis within the canopy and the effect of current shear on recruitment of organisms on the blades. It can also be used to study how eelgrass canopies affect horizontal transport of constituents, such as dissolved oxygen, nutrients and organic carbon, and particulate material such as pollen, larvae, plankton and detritus. JF - Marine Ecology Progress Series AU - Abdelrhman, Mohamed A AD - US Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Atlantic Ecology Division, 27 Tarzwell Drive, Narragansett, Rhode Island 02882, USA, abdelrhman.mohamed@epa.gov Y1 - 2007/03// PY - 2007 DA - March 2007 SP - 81 EP - 96 PB - Inter-Research, Nordbuente 23 Oldendorf/Luhe 21385 Germany, [mailto:ir@int-res.com] VL - 338 SN - 0171-8630, 0171-8630 KW - Eel grass KW - Sustainability Science Abstracts; Ecology Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Model KW - Coupling KW - Eelgrass KW - Current KW - Canopy height KW - Shear KW - Photosynthesis KW - Marine KW - Vertical distribution KW - Plankton surveys