TY - CPAPER T1 - The Influence of an Invasive Shrub, Buddleja davidii, on a Native Shrub, Griselinia littoralis, Transplanted in a Floodplain Chronosequence in New Zealand T2 - 93rd Annual Meeting of the Ecological Society of America (ESA 2008) AN - 41072172; 4918683 JF - 93rd Annual Meeting of the Ecological Society of America (ESA 2008) AU - Tallent-Halsell, Nita G AU - Walker, Lawrence R Y1 - 2008/08/03/ PY - 2008 DA - 2008 Aug 03 KW - New Zealand KW - Shrubs KW - Flood plains KW - Buddleja davidii UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41072172?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=93rd+Annual+Meeting+of+the+Ecological+Society+of+America+%28ESA+2008%29&rft.atitle=The+Influence+of+an+Invasive+Shrub%2C+Buddleja+davidii%2C+on+a+Native+Shrub%2C+Griselinia+littoralis%2C+Transplanted+in+a+Floodplain+Chronosequence+in+New+Zealand&rft.au=Tallent-Halsell%2C+Nita+G%3BWalker%2C+Lawrence+R&rft.aulast=Tallent-Halsell&rft.aufirst=Nita&rft.date=2008-08-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=93rd+Annual+Meeting+of+the+Ecological+Society+of+America+%28ESA+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2008/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Hydrology and Hyporheic Nitrogen Biogeochemistry in a Geomorphically Degraded Urban Stream T2 - 93rd Annual Meeting of the Ecological Society of America (ESA 2008) AN - 41069860; 4918957 JF - 93rd Annual Meeting of the Ecological Society of America (ESA 2008) AU - Mayer, Paul AU - Groffman, Peter M AU - Kaushal, Sujay S AU - Striz, Elise Y1 - 2008/08/03/ PY - 2008 DA - 2008 Aug 03 KW - Biogeochemistry KW - Hydrology KW - Nitrogen KW - Streams KW - Geomorphology KW - Fluvial morphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41069860?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=93rd+Annual+Meeting+of+the+Ecological+Society+of+America+%28ESA+2008%29&rft.atitle=Hydrology+and+Hyporheic+Nitrogen+Biogeochemistry+in+a+Geomorphically+Degraded+Urban+Stream&rft.au=Mayer%2C+Paul%3BGroffman%2C+Peter+M%3BKaushal%2C+Sujay+S%3BStriz%2C+Elise&rft.aulast=Mayer&rft.aufirst=Paul&rft.date=2008-08-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=93rd+Annual+Meeting+of+the+Ecological+Society+of+America+%28ESA+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2008/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Synthesis of Lead Pyrophosphate, Pb2P2O7, in Water AN - 745714909; 11930178 AB - Polyphosphates are used in drinking water to prevent the precipitation of cations such as calcium and iron. The possible negative impact of using polyphosphates is the undesirable complexation of lead that could result in elevated lead levels in consumers' tap water. Although the water industry has focused on complexation, lead polyphosphate solids such as lead pyrophosphate, Pb2P2O7, have been considered in other fields and not been shown to form in water. The ability to form lead pyrophosphate in water could have a potential impact on the strategies used to reduce lead levels in drinking water distribution systems. The objective of this work was to determine whether lead pyrophosphate could form under simulated potable drinking water conditions. Lead pyrophosphate was synthesized in water (pH 8.2, 10 mg C/L, 2.7 mg Cl2/L) after 13 days of aging. The formation of lead pyrophosphate was confirmed by X-ray diffraction and microscopy analysis. Synthesis did not require elevated temperatures or microwave assisted approaches used by past researchers. The findings suggest that lead (and possibly other metal) pyrophosphates could conceivably form in real drinking water systems, although much more work is necessary to determine the chemistry and kinetic boundaries. JF - Microscopy and Microanalysis AU - Lytle, Darren A AU - White, Colin AU - Schock, Michael R AD - U.S. Environmental Protection Agency, Treatment Technology Evaluation Branch, Cincinnati, OH 45268, USA, lytle.darren@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 335 EP - 341 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU UK VL - 14 IS - 4 SN - 1431-9276, 1431-9276 KW - Pollution Abstracts; Water Resources Abstracts KW - Metals KW - Calcium KW - Temperature KW - Solids KW - X-ray diffraction KW - Water quality KW - Lead KW - Drinking Water KW - Cations KW - Kinetics KW - Microscopy KW - Boundaries KW - Synthesis KW - Drinking water KW - Iron KW - pH KW - aging KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745714909?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Microscopy+and+Microanalysis&rft.atitle=Synthesis+of+Lead+Pyrophosphate%2C+Pb2P2O7%2C+in+Water&rft.au=Lytle%2C+Darren+A%3BWhite%2C+Colin%3BSchock%2C+Michael+R&rft.aulast=Lytle&rft.aufirst=Darren&rft.date=2008-08-01&rft.volume=14&rft.issue=4&rft.spage=335&rft.isbn=&rft.btitle=&rft.title=Microscopy+and+Microanalysis&rft.issn=14319276&rft_id=info:doi/10.1017%2FS1431927608080689 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Metals; Calcium; Temperature; Water quality; X-ray diffraction; Lead; Cations; Kinetics; Microscopy; Drinking water; Iron; pH; aging; Drinking Water; Boundaries; Solids; Synthesis DO - http://dx.doi.org/10.1017/S1431927608080689 ER - TY - JOUR T1 - Polybrominated diphenyl ethers: causes for concern and knowledge gaps regarding environmental distribution, fate and toxicity. AN - 69734572; 18571221 AB - This manuscript critically considers several areas of study of the polybrominated diphenyl ether compounds. Specifically, a brief review of PBDE toxicity is followed by an in depth discussion of PBDE occurrence in abiotic and biotic environmental matrices. Temporal and geographic trends are examined in conjunction with risk assessment factors. Rather than summarize or tabulate the growing body of literature on PBDEs in the environment, the overall goal of this review paper is to highlight broad patterns that may contribute to a more holistic understanding of PBDE behavior in the environment, as well as to identify critical areas of research that warrant further attention. JF - The Science of the total environment AU - Vonderheide, Anne P AU - Mueller, Kevin E AU - Meija, Juris AU - Welsh, Gwendolyn L AD - United States Environmental Protection Agency, National Exposure Research Laboratory, Microbiological and Chemical Exposure Assessment Research Division, Chemical Exposure Research Branch, Cincinnati, Ohio 45268, USA. vonderheide.anne@epa.gov Y1 - 2008/08/01/ PY - 2008 DA - 2008 Aug 01 SP - 425 EP - 436 VL - 400 IS - 1-3 SN - 0048-9697, 0048-9697 KW - Environmental Pollutants KW - 0 KW - Halogenated Diphenyl Ethers KW - Index Medicus KW - Ecosystem KW - Animals KW - Humans KW - Geography KW - Risk Assessment KW - Biological Availability KW - Environmental Pollutants -- toxicity KW - Environmental Exposure KW - Halogenated Diphenyl Ethers -- chemistry KW - Environmental Pollutants -- chemistry KW - Halogenated Diphenyl Ethers -- analysis KW - Environmental Pollutants -- analysis KW - Halogenated Diphenyl Ethers -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69734572?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Polybrominated+diphenyl+ethers%3A+causes+for+concern+and+knowledge+gaps+regarding+environmental+distribution%2C+fate+and+toxicity.&rft.au=Vonderheide%2C+Anne+P%3BMueller%2C+Kevin+E%3BMeija%2C+Juris%3BWelsh%2C+Gwendolyn+L&rft.aulast=Vonderheide&rft.aufirst=Anne&rft.date=2008-08-01&rft.volume=400&rft.issue=1-3&rft.spage=425&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2008.05.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-01-15 N1 - Date created - 2008-10-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.scitotenv.2008.05.003 ER - TY - JOUR T1 - Uncertainties in biologically-based modeling of formaldehyde-induced respiratory cancer risk: identification of key issues. AN - 69514476; 18564991 AB - In a series of articles and a health-risk assessment report, scientists at the CIIT Hamner Institutes developed a model (CIIT model) for estimating respiratory cancer risk due to inhaled formaldehyde within a conceptual framework incorporating extensive mechanistic information and advanced computational methods at the toxicokinetic and toxicodynamic levels. Several regulatory bodies have utilized predictions from this model; on the other hand, upon detailed evaluation the California EPA has decided against doing so. In this article, we study the CIIT model to identify key biological and statistical uncertainties that need careful evaluation if such two-stage clonal expansion models are to be used for extrapolation of cancer risk from animal bioassays to human exposure. Broadly, these issues pertain to the use and interpretation of experimental labeling index and tumor data, the evaluation and biological interpretation of estimated parameters, and uncertainties in model specification, in particular that of initiated cells. We also identify key uncertainties in the scale-up of the CIIT model to humans, focusing on assumptions underlying model parameters for cell replication rates and formaldehyde-induced mutation. We discuss uncertainties in identifying parameter values in the model used to estimate and extrapolate DNA protein cross-link levels. The authors of the CIIT modeling endeavor characterized their human risk estimates as "conservative in the face of modeling uncertainties." The uncertainties discussed in this article indicate that such a claim is premature. JF - Risk analysis : an official publication of the Society for Risk Analysis AU - Subramaniam, Ravi P AU - Chen, Chao AU - Crump, Kenny S AU - Devoney, Danielle AU - Fox, John F AU - Portier, Christopher J AU - Schlosser, Paul M AU - Thompson, Chad M AU - White, Paul AD - NCEA, ORD, U.S. Environmental Protection Agency, Pennsylvania Ave. NW, Washington, DC 20460, USA. Subramaniam.Ravi@epa.gov Y1 - 2008/08// PY - 2008 DA - August 2008 SP - 907 EP - 923 VL - 28 IS - 4 KW - Carcinogens KW - 0 KW - Formaldehyde KW - 1HG84L3525 KW - Index Medicus KW - Dose-Response Relationship, Drug KW - Humans KW - Risk Assessment KW - Uncertainty KW - Respiratory Tract Neoplasms -- chemically induced KW - Carcinogens -- toxicity KW - Formaldehyde -- toxicity KW - Models, Theoretical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69514476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.atitle=Uncertainties+in+biologically-based+modeling+of+formaldehyde-induced+respiratory+cancer+risk%3A+identification+of+key+issues.&rft.au=Subramaniam%2C+Ravi+P%3BChen%2C+Chao%3BCrump%2C+Kenny+S%3BDevoney%2C+Danielle%3BFox%2C+John+F%3BPortier%2C+Christopher+J%3BSchlosser%2C+Paul+M%3BThompson%2C+Chad+M%3BWhite%2C+Paul&rft.aulast=Subramaniam&rft.aufirst=Ravi&rft.date=2008-08-01&rft.volume=28&rft.issue=4&rft.spage=907&rft.isbn=&rft.btitle=&rft.title=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.issn=1539-6924&rft_id=info:doi/10.1111%2Fj.1539-6924.2008.01083.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-11-14 N1 - Date created - 2008-09-04 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Cell Mol Life Sci. 2004 Mar;61(5):610-7 [15004699] Carcinogenesis. 1999 Mar;20(3):383-9 [10190550] Ann Otol Rhinol Laryngol. 1970 Jun;79(3):572-8 [4913320] Cancer Res. 1980 Apr;40(4):1157-64 [6101993] Cancer Res. 1983 Sep;43(9):4382-92 [6871871] Cancer Res. 1984 Dec;44(12 Pt 1):5463-74 [6388826] Cancer Res. 1986 May;46(5):2377-85 [3697980] Risk Anal. 1988 Sep;8(3):383-92 [3201016] Toxicol Pathol. 1990;18(1 Pt 1):24-31 [2194274] Risk Anal. 1990 Jun;10(2):323-41 [2195604] Environ Health Perspect. 2000 May;108 Suppl 2:241-59 [10807555] Carcinogenesis. 2000 Jul;21(7):1411-21 [10874021] Carcinogenesis. 2000 Aug;21(8):1573-80 [10910961] Toxicol Appl Pharmacol. 2000 Aug 15;167(1):63-73 [10936080] Environ Health Perspect. 2000 Oct;108 Suppl 5:919-24 [11036001] Am J Pathol. 2000 Nov;157(5):1745-55 [11073833] Cell Prolif. 2001 Jun;34(3):135-41 [11380483] J Appl Physiol (1985). 2001 Aug;91(2):725-32 [11457787] Toxicol Sci. 2001 Nov;64(1):100-10 [11606806] Toxicol Sci. 2001 Nov;64(1):111-21 [11606807] Toxicol Sci. 2001 Nov;64(1):122-34 [11606808] Pharmacogenetics. 2001 Dec;11(9):815-24 [11740346] Regul Toxicol Pharmacol. 2002 Feb;35(1):32-43 [11846634] J Toxicol Environ Health B Crit Rev. 2003 Jan-Feb;6(1):85-114 [12587255] Occup Environ Med. 2003 Jun;60(6):403-9 [12771391] DNA Repair (Amst). 2003 Sep 18;2(9):947-54 [12967652] Toxicol Sci. 2003 Oct;75(2):432-47 [12857938] Inhal Toxicol. 2003 Dec;15(14):1435-63 [14648358] Toxicol Sci. 2004 Jan;77(1):158-64 [14600280] Toxicol Sci. 2004 Jan;77(1):151-7 [14600281] Toxicol Appl Pharmacol. 1991 Dec;111(3):409-21 [1746023] Toxicol Appl Pharmacol. 1991 Dec;111(3):469-84 [1684071] Carcinogenesis. 1992 Jun;13(6):1007-10 [1600603] Carcinogenesis. 1992 Jun;13(6):973-8 [1600619] Cancer Res. 1992 Nov 1;52(21):6113-6 [1394239] Risk Anal. 1994 Dec;14(6):879-82 [7846320] Toxicol Appl Pharmacol. 1995 Feb;130(2):304-15 [7532877] Toxicol Appl Pharmacol. 1995 May;132(1):27-35 [7747282] Toxicology. 1995 Sep 1;102(1-2):161-75 [7482551] Arch Otolaryngol Head Neck Surg. 1996 Apr;122(4):432-6 [8600930] Toxicol Appl Pharmacol. 1996 May;138(1):20-30 [8658509] Cancer Res. 1996 Mar 1;56(5):1012-22 [8640755] Toxicol Pathol. 1997 Jan-Feb;25(1):89-93 [9061858] Toxicol Pathol. 1997 May-Jun;25(3):291-307 [9210261] Mutat Res. 1997 Oct 31;380(1-2):27-31 [9385387] IARC Sci Publ. 1999;(146):273-85 [10353391] Toxicol Appl Pharmacol. 1999 Oct 1;160(1):86-100 [10502505] Mutat Res. 2005 Mar;589(2):111-35 [15795165] J Exp Biol. 2005 May;208(Pt 9):1575-92 [15855389] Mutat Res. 2006 Sep;613(1):1-9 [16638643] J Allergy Clin Immunol. 2007 Aug;120(2):322-8 [17543375] Risk Anal. 2007 Oct;27(5):1237-54 [18076493] Altern Lab Anim. 2007 Dec;35(6):621-39 [18186669] Inhal Toxicol. 2009 Jun;21(7):607-18 [19459775] Mutat Res. 1997 Oct 31;380(1-2):143-54 [9385395] Clin Anat. 1998;11(3):162-70 [9579588] Environ Mol Mutagen. 1998;32(3):260-8 [9814441] Hum Exp Toxicol. 1998 Dec;17(12):691-6; discussion 701-4, 708-18 [9988374] Toxicol Sci. 2004 Nov;82(1):279-96 [15254341] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1539-6924.2008.01083.x ER - TY - JOUR T1 - Pentachlorophenol and cancer risk: focusing the lens on specific chlorophenols and contaminants. AN - 69431695; 18709150 AB - Pentachlorophenol, a fungicide widely used as a wood preservative, was classified in 1999 by the International Agency for Research on Cancer as a possible human carcinogen. We reviewed currently available data to determine the extent to which recent studies assist in distinguishing the effect of pentachlorophenol from that of its contaminants (e.g., dioxins and other chlorophenols). We performed a systematic review of published studies pertaining to cancer risk in relation to pentachlorophenol exposure, focusing on results pertaining specifically to all cancer sites and specific hematopoietic cancers, and data pertaining to risks associated with other types of chlorophenols, dioxins, or furans. The pentachlorophenol studies presented considerable evidence pertaining to hematopoietic cancers, with strong associations seen in multiple studies, in different locations, and using different designs. There is little evidence of an association between these cancers and chlorophenols that contain fewer than four chlorines. The extension of a large cohort study of sawmill workers, with follow-up to 1995, provided information about risks of relatively rare cancers (e.g., non-Hodgkin lymphoma, multiple myeloma), using a validated exposure assessment procedure that distinguishes between exposures to pentachlorophenol and tetrachlorophenol. In contrast with dioxin, pentachlorophenol exposure has not been associated with total cancer incidence or mortality. The updated cohort study focusing on pentachlorophenol provides increased statistical power and precision, and demonstrates associations between hematopoietic cancer and pentachlorophenol exposure not observed in earlier evaluations of this cohort. Contaminant confounding is an unlikely explanation for the risks seen with pentachlorophenol exposure. JF - Environmental health perspectives AU - Cooper, Glinda S AU - Jones, Samantha AD - National Center for Environmental Assessment, US Environmental Protection Agency, Washington, DC 20460, USA. cooper.glinda@epa.gov Y1 - 2008/08// PY - 2008 DA - August 2008 SP - 1001 EP - 1008 VL - 116 IS - 8 SN - 0091-6765, 0091-6765 KW - Carcinogens KW - 0 KW - Chlorophenols KW - Dioxins KW - Fungicides, Industrial KW - Pentachlorophenol KW - D9BSU0SE4T KW - Index Medicus KW - multiple myeloma KW - furans KW - pentachlorophenol KW - dioxins KW - chlorophenols KW - non-Hodgkin lymphoma KW - soft-tissue sarcoma KW - childhood leukemia KW - cancer KW - Aged, 80 and over KW - Humans KW - Cohort Studies KW - Adult KW - Environmental Exposure KW - Case-Control Studies KW - Incidence KW - Aged KW - Middle Aged KW - Child KW - Male KW - Female KW - Risk Assessment KW - Hematologic Neoplasms -- chemically induced KW - Chlorophenols -- toxicity KW - Carcinogens -- toxicity KW - Hematologic Neoplasms -- epidemiology KW - Fungicides, Industrial -- toxicity KW - Dioxins -- toxicity KW - Pentachlorophenol -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69431695?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Pentachlorophenol+and+cancer+risk%3A+focusing+the+lens+on+specific+chlorophenols+and+contaminants.&rft.au=Cooper%2C+Glinda+S%3BJones%2C+Samantha&rft.aulast=Cooper&rft.aufirst=Glinda&rft.date=2008-08-01&rft.volume=116&rft.issue=8&rft.spage=1001&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.11081 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-10 N1 - Date created - 2008-08-18 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Cancer. 1990 Aug 15;66(4):806-11 [2386907] J Expo Sci Environ Epidemiol. 2007 Sep;17(6):541-8 [17426737] Arch Environ Health. 1992 May-Jun;47(3):167-75 [1596099] Am J Ind Med. 1993 Jul;24(1):81-92 [8352294] Int Arch Occup Environ Health. 1993;65(1):1-8 [8354568] Cancer Res. 1994 May 1;54(9):2386-9 [8162585] Epidemiology. 1995 Jul;6(4):396-402 [7548348] Am J Ind Med. 1996 Aug;30(2):180-94 [8844048] Am J Ind Med. 1996 Nov;30(5):616-22 [8909611] Am J Public Health. 1997 Jan;87(1):71-9 [9065230] Am J Epidemiol. 1997 Jun 15;145(12):1061-75 [9199536] Am J Epidemiol. 1998 May 1;147(9):891-901 [9583720] Am J Epidemiol. 1998 Oct 1;148(7):693-703 [9778176] J Occup Environ Med. 1999 Apr;41(4):267-72 [10224592] Hum Exp Toxicol. 2004 Oct;23(10):463-71 [15553171] Am J Ind Med. 2000 May;37(5):532-41 [10723047] Environ Health Perspect. 2000 Jun;108(6):499-503 [10856022] Curr Opin Immunol. 2002 Apr;14(2):165-71 [11869887] Int J Cancer. 2002 May 1;99(1):119-23 [11948502] Toxicol Rev. 2003;22(1):3-11 [14579543] Environ Health Perspect. 2004 Sep;112(13):1265-8 [15345337] J Occup Environ Med. 2004 Sep;46(9):985-92 [15354065] Toxicol Appl Pharmacol. 1974 Apr;28(1):151-61 [4854776] Lancet. 1978 Sep 16;2(8090):626-7 [80546] Br J Cancer. 1979 Jun;39(6):711-7 [444410] Crit Rev Toxicol. 1980 Jul;7(1):1-35 [6996925] Br J Cancer. 1981 Feb;43(2):169-76 [7470379] Br J Ind Med. 1981 Feb;38(1):27-33 [7470401] Lancet. 1981 Aug 15;2(8242):369 [6115144] J Natl Cancer Inst. 1984 Nov;73(5):1111-7 [6593487] Br J Ind Med. 1986 Feb;43(2):75-83 [3753879] Br J Cancer. 1986 Sep;54(3):493-500 [3756085] J Natl Cancer Inst. 1987 May;78(5):899-910 [3471999] J Occup Med. 1987 May;29(5):422-9 [2439670] Cancer. 1988 Aug 1;62(3):652-6 [3390800] Scand J Work Environ Health. 1989 Feb;15(1):18-23 [2922584] Am J Ind Med. 1988;14(6):703-13 [3232688] Scand J Work Environ Health. 1989 Dec;15(6):424-9 [2617258] J Natl Cancer Inst. 1990 Mar 21;82(6):486-90 [2313720] Arch Environ Contam Toxicol. 1990 Jul-Aug;19(4):603-9 [2386415] Occup Environ Med. 2005 Jul;62(7):461-4 [15961622] Environ Toxicol. 2005 Aug;20(4):418-24 [16007644] Cancer Res. 2005 Dec 1;65(23):11214-26 [16322272] Cancer Causes Control. 2006 Aug;17(6):749-58 [16783603] Occup Environ Med. 2006 Oct;63(10):663-8 [16757510] Int J Hyg Environ Health. 2007 May;210(3-4):271-97 [17347043] Br J Cancer. 1992 Mar;65(3):442-8 [1558802] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1289/ehp.11081 ER - TY - JOUR T1 - A physiologically based pharmacokinetic model for intravenous and ingested dimethylarsinic acid in mice. AN - 69314237; 18430741 AB - A physiologically based pharmacokinetic (PBPK) model for the organoarsenical dimethylarsinic acid (DMA(V)) was developed in mice. The model was calibrated using tissue time course data from multiple tissues in mice administered DMA(V) intravenously. The final model structure was based on diffusion limitation kinetics. In general, PBPK models use the assumption of blood flow-limited transport into tissues. This assumption has historically worked for small lipophilic organic solvents. However, the conditions under which flow-limited kinetics occurs and how to distinguish when flow-limited versus diffusion-limited transport is more appropriate, have been rarely evaluated. One important goal of this modeling effort was to systematically evaluate descriptions of flow-limited compared with diffusion-limited tissue distribution for DMA(V), using the relatively extensive pharmacokinetic data available in mice. The diffusion-limited model consistently provided an improved fit over flow-limited simulations when compared with tissue time course iv experimental data. After model calibration, an independent data set obtained by oral gavage of DMA(V), was used to further test model structure. Sensitivity analysis of the two PBPK model structures showed the importance of early time course data collection, and the impact of diffusion for kidney time course data description. In summary, this modeling effort suggests the importance of availability of organ specific time course data sets necessary for the discernment of PBPK modeling structure, motivated by knowledge of biology, and providing necessary feedback between experimental design and biological modelers. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Evans, Marina V AU - Dowd, Sean M AU - Kenyon, Elaina M AU - Hughes, Michael F AU - El-Masri, Hisham A AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. evans.marina@epa.gov Y1 - 2008/08// PY - 2008 DA - August 2008 SP - 250 EP - 260 VL - 104 IS - 2 KW - Herbicides KW - 0 KW - Cacodylic Acid KW - AJ2HL7EU8K KW - Index Medicus KW - Sensitivity and Specificity KW - Administration, Oral KW - Animals KW - Injections, Intravenous KW - Dose-Response Relationship, Drug KW - Mice KW - Tissue Distribution KW - Models, Biological KW - Female KW - Herbicides -- pharmacokinetics KW - Cacodylic Acid -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69314237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=A+physiologically+based+pharmacokinetic+model+for+intravenous+and+ingested+dimethylarsinic+acid+in+mice.&rft.au=Evans%2C+Marina+V%3BDowd%2C+Sean+M%3BKenyon%2C+Elaina+M%3BHughes%2C+Michael+F%3BEl-Masri%2C+Hisham+A&rft.aulast=Evans&rft.aufirst=Marina&rft.date=2008-08-01&rft.volume=104&rft.issue=2&rft.spage=250&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=1096-0929&rft_id=info:doi/10.1093%2Ftoxsci%2Fkfn080 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-28 N1 - Date created - 2008-07-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/toxsci/kfn080 ER - TY - JOUR T1 - Approaches for applications of physiologically based pharmacokinetic models in risk assessment. AN - 69259262; 18584453 AB - Physiologically based pharmacokinetic (PBPK) models are particularly useful for simulating exposures to environmental toxicants for which, unlike pharmaceuticals, there is often little or no human data available to estimate the internal dose of a putative toxic moiety in a target tissue or an appropriate surrogate. This article reviews the current state of knowledge and approaches for application of PBPK models in the process of deriving reference dose, reference concentration, and cancer risk estimates. Examples drawn from previous U.S. Environmental Protection Agency (EPA) risk assessments and human health risk assessments in peer-reviewed literature illustrate the ways and means of using PBPK models to quantify the pharmacokinetic component of the interspecies and intraspecies uncertainty factors as well as to conduct route to route, high dose to low dose and duration extrapolations. The choice of the appropriate dose metric is key to the use of the PBPK models for the various applications in risk assessment. Issues related to whether uncertainty factors are most appropriately applied before or after derivation of human equivalent dose (or concentration) continue to be explored. Scientific progress in the understanding of life stage and genetic differences in dosimetry and their impacts on variability in susceptibility, as well as ongoing development of analytical methods to characterize uncertainty in PBPK models, will make their use in risk assessment increasingly likely. As such, it is anticipated that when PBPK models are used to express adverse tissue responses in terms of the internal target tissue dose of the toxic moiety rather than the external concentration, the scientific basis of, and confidence in, risk assessments will be enhanced. JF - Journal of toxicology and environmental health. Part B, Critical reviews AU - Thompson, Chad M AU - Sonawane, Babasaheb AU - Barton, Hugh A AU - DeWoskin, Robert S AU - Lipscomb, John C AU - Schlosser, Paul AU - Chiu, Weihsueh A AU - Krishnan, Kannan AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, USA. Y1 - 2008/08// PY - 2008 DA - August 2008 SP - 519 EP - 547 VL - 11 IS - 7 KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - United States KW - Animals KW - United States Environmental Protection Agency KW - Dose-Response Relationship, Drug KW - Humans KW - Tissue Distribution KW - Species Specificity KW - Risk Assessment KW - Environmental Exposure KW - Models, Biological KW - Environmental Pollutants -- administration & dosage KW - Environmental Pollutants -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69259262?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+B%2C+Critical+reviews&rft.atitle=Approaches+for+applications+of+physiologically+based+pharmacokinetic+models+in+risk+assessment.&rft.au=Thompson%2C+Chad+M%3BSonawane%2C+Babasaheb%3BBarton%2C+Hugh+A%3BDeWoskin%2C+Robert+S%3BLipscomb%2C+John+C%3BSchlosser%2C+Paul%3BChiu%2C+Weihsueh+A%3BKrishnan%2C+Kannan&rft.aulast=Thompson&rft.aufirst=Chad&rft.date=2008-08-01&rft.volume=11&rft.issue=7&rft.spage=519&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+B%2C+Critical+reviews&rft.issn=1521-6950&rft_id=info:doi/10.1080%2F10937400701724337 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-15 N1 - Date created - 2008-06-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/10937400701724337 ER - TY - JOUR T1 - A late Paleocene tempestite deposit exposed along a section of Hurricane Creek, Dale County, Alabama AN - 50391884; 2009-067421 JF - Southeastern Geology AU - Froede, Carl R, Jr Y1 - 2008/08// PY - 2008 DA - August 2008 SP - 233 EP - 244 PB - Duke University, Department of Geology, Durham, NC VL - 45 IS - 4 SN - 0038-3678, 0038-3678 KW - United States KW - shells KW - clastic sediments KW - biogenic structures KW - Tascahoma Sand Formation KW - Paleogene KW - nearshore environment KW - Gulf Coastal Plain KW - Alabama KW - upper Paleocene KW - Cenozoic KW - Tertiary KW - debris KW - marine environment KW - Paleocene KW - Dale County Alabama KW - sediments KW - Hurricane Creek KW - tempestite KW - depositional environment KW - estuarine environment KW - sedimentary structures KW - bioturbation KW - 06A:Sedimentary petrology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50391884?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Southeastern+Geology&rft.atitle=A+late+Paleocene+tempestite+deposit+exposed+along+a+section+of+Hurricane+Creek%2C+Dale+County%2C+Alabama&rft.au=Froede%2C+Carl+R%2C+Jr&rft.aulast=Froede&rft.aufirst=Carl&rft.date=2008-08-01&rft.volume=45&rft.issue=4&rft.spage=233&rft.isbn=&rft.btitle=&rft.title=Southeastern+Geology&rft.issn=00383678&rft_id=info:doi/ L2 - http://www.southeasterngeology.org/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 38 N1 - PubXState - NC N1 - Document feature - illus. incl. 3 plates, sketch maps N1 - Last updated - 2012-06-07 N1 - CODEN - SOGEAY N1 - SubjectsTermNotLitGenreText - Alabama; biogenic structures; bioturbation; Cenozoic; clastic sediments; Dale County Alabama; debris; depositional environment; estuarine environment; Gulf Coastal Plain; Hurricane Creek; marine environment; nearshore environment; Paleocene; Paleogene; sedimentary structures; sediments; shells; Tascahoma Sand Formation; tempestite; Tertiary; United States; upper Paleocene ER - TY - JOUR T1 - Experimental design considerations for verifying the performance of screening technologies for dioxin and dioxin-like compounds in soils and sediments AN - 50232951; 2009-086146 JF - Chemosphere (Oxford) AU - Dindal, Amy AU - Billets, Stephen A2 - Alaee, Mehran A2 - Arsenault, Gilles A2 - Parrott, Joanne A2 - Reiner, Eric J. Y1 - 2008/08// PY - 2008 DA - August 2008 SP - S66 EP - S71 PB - Elsevier VL - 73 IS - 1S SN - 0045-6535, 0045-6535 KW - soils KW - chlorinated hydrocarbons KW - concentration KW - technology KW - pollutants KW - PCBs KW - pollution KW - techniques KW - dioxins KW - remediation KW - measurement KW - polychlorinated dibenzofurans KW - organic compounds KW - detection KW - toxicity KW - sediments KW - halogenated hydrocarbons KW - testing KW - accuracy KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50232951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere+%28Oxford%29&rft.atitle=Experimental+design+considerations+for+verifying+the+performance+of+screening+technologies+for+dioxin+and+dioxin-like+compounds+in+soils+and+sediments&rft.au=Dindal%2C+Amy%3BBillets%2C+Stephen&rft.aulast=Dindal&rft.aufirst=Amy&rft.date=2008-08-01&rft.volume=73&rft.issue=1S&rft.spage=S66&rft.isbn=&rft.btitle=&rft.title=Chemosphere+%28Oxford%29&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2006.12.104 L2 - http://www.sciencedirect.com/science/journal/00456535 LA - English DB - GeoRef N1 - Conference title - 25th international symposium on Halogenated environmental organic pollutants and POPs; Dioxin 2005 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 13 N1 - Document feature - 4 tables N1 - Last updated - 2012-06-07 N1 - CODEN - CMSHAF N1 - SubjectsTermNotLitGenreText - accuracy; chlorinated hydrocarbons; concentration; detection; dioxins; halogenated hydrocarbons; measurement; organic compounds; PCBs; pollutants; pollution; polychlorinated dibenzofurans; remediation; sediments; soils; techniques; technology; testing; toxicity DO - http://dx.doi.org/10.1016/j.chemosphere.2006.12.104 ER - TY - JOUR T1 - The application of genetic information for regulatory standard setting under the Clean Air Act: a decision-analytic approach AN - 37103955; 3851455 AB - In 2002, the U.S. Environmental Protection Agency (EPA) released an 'Interim Policy on Genomics,' stating a commitment to developing guidance on the inclusion of genetic information in regulatory decision making. This statement was followed in 2004 by a document exploring the potential implications. Genetic information can play a key role in understanding and quantifying human susceptibility, an essential step in many of the risk assessments used to shape policy. For example, the federal Clean Air Act (CAA) requires EPA to set National Ambient Air Quality Standards (NAAQS) for criteria pollutants at levels to protect even sensitive populations from adverse health effects with an adequate margin of safety. Asthmatics are generally regarded as a sensitive population, yet substantial research gaps in understanding genetic susceptibility and disease have hindered quantitative risk analysis. This case study assesses the potential role of genomic information regarding susceptible population in the NAAQS process for fine particulate matter (PM2.5) under the CAA. In this initial assessment, we model the contribution of a single polymorphism to asthma risk and mortality risk; however, multiple polymorphisms and interactions (gene-gene and gene-environment) are known to play key roles in the disease process. We show that the impact of new information about susceptibility on estimates of population risk or average risk derived from large epidemiological studies depends on the circumstances. We also suggest that analysis of a single polymorphism, or other risk factor such as health status, may or may not change estimates of individual risk enough to alter a particular regulatory decision, but this depends on specific characteristics of the decision and risk information. We also show how new information about susceptibility in the context of the NAAQS for PM2.5 could have a large impact on the estimated distribution of individual risk. This would occur if a group were consequently identified (based on genetic and/or disease status), that accounted for a disproportionate share of observed effects. Our results highlight certain conditions under which genetic information is likely to have an impact on risk estimates and the balance of costs and benefits within groups, and highlight critical research needs. As future studies explore more fully the relationship between exposure, genetic makeup, and disease status, the opportunity for genetic information and disease status to play pivotal roles in regulation can only increase. Reprinted by permission of Blackwell Publishers JF - Risk analysis AU - Cullen, Alison C AU - Corrales, Mark A AU - Kramer, C Bradley AU - Faustman, Elaine M AD - University of Washington ; U.S. Environmental Protection Agency Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 877 EP - 890 VL - 28 IS - 4 SN - 0272-4332, 0272-4332 KW - Political Science KW - Sociology KW - Asthma KW - Risk aversion KW - Genetics KW - Risk management KW - Epidemiology KW - DNA KW - U.S.A. KW - Environmental protection KW - Pollution control KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37103955?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Risk+analysis&rft.atitle=The+application+of+genetic+information+for+regulatory+standard+setting+under+the+Clean+Air+Act%3A+a+decision-analytic+approach&rft.au=Cullen%2C+Alison+C%3BCorrales%2C+Mark+A%3BKramer%2C+C+Bradley%3BFaustman%2C+Elaine+M&rft.aulast=Cullen&rft.aufirst=Alison&rft.date=2008-08-01&rft.volume=28&rft.issue=4&rft.spage=877&rft.isbn=&rft.btitle=&rft.title=Risk+analysis&rft.issn=02724332&rft_id=info:doi/10.1111%2Fj.1539-6924.2008.01084.x LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 11038 7625; 5460 1615 8573 11325; 11036 11040 11035; 4339; 3254 5460 1615 8573 11325; 10449 5772; 4357 7894; 9819 9818; 433 293 14 DO - http://dx.doi.org/10.1111/j.1539-6924.2008.01084.x ER - TY - JOUR T1 - Bush v. Gore and the effect of new source review on power plant emissions AN - 37071562; 3823378 AB - New Source Review (NSR) is a Clean Air Act regulation that requires electric utilities to meet emission standards when making modifications to existing power plants. The regulation increases the cost of replacing worn out parts, and limits the firm's scope of potential capital investments. Such restrictions may lead to greater retirements and lower utilization, adversely affecting profits. Prior to the 2000 presidential election, investors expected Bush to have a narrower interpretation of NSR than Gore. Therefore, we use changes in stock prices to estimate the effect on profits of differences in NSR policy. Our results indicate that investors expected the average boilers' lifetimes, the additional utilization will have increased emissions by 19 million tons of sulfur dioxide, 5.9 million tons of nitrogen oxides and 980 million tons of carbon dioxide, relative to natural gas generation. Reprinted by permission of Springer JF - Environmental and resource economics AU - Lange, I AU - Linn, J AD - Environmental Protection Agency ; University of Illinois, Chicago Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 571 EP - 592 VL - 40 IS - 4 SN - 0924-6460, 0924-6460 KW - Economics KW - Bush, George W. KW - Gore, Al KW - Environment KW - Air pollution KW - Presidential elections KW - Power plants KW - Stocks KW - Regulation KW - Investment KW - Carbon emissions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37071562?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+and+resource+economics&rft.atitle=Bush+v.+Gore+and+the+effect+of+new+source+review+on+power+plant+emissions&rft.au=Lange%2C+I%3BLinn%2C+J&rft.aulast=Lange&rft.aufirst=I&rft.date=2008-08-01&rft.volume=40&rft.issue=4&rft.spage=571&rft.isbn=&rft.btitle=&rft.title=Environmental+and+resource+economics&rft.issn=09246460&rft_id=info:doi/10.1007%2Fs10640-007-9170-z LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 9974; Carbon emissions; 891 9818; 10742; 6852; 10058 4128; 12290; 4309 DO - http://dx.doi.org/10.1007/s10640-007-9170-z ER - TY - JOUR T1 - Molecular Comparison of Mycobacterium avium Isolates from Clinical and Environmental Sources AN - 21506993; 12494705 AB - We collected Mycobacterium avium isolates from clinical and drinking-water sources and compared isolates among themselves and to each other using molecular methods. Four clinical isolates were related to water isolates. Groups of indistinguishable clinical isolates were identified. The groups of identical clinical isolates suggest a common source of exposure. JF - Applied and Environmental Microbiology AU - Hilborn, Elizabeth D AU - Yakrus, Mitchell A AU - Covert, Terry C AU - Harris, Stephanie I AU - Donnelly, Sandra F AU - Schmitt, Michael T AU - Toney, Sean AU - Bailey, Stephanie A AU - Stelma Jr. Jr, Gerard N AD - U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina, hilborn.e@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 4966 EP - 4968 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 74 IS - 15 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Clinical isolates KW - Mycobacterium avium KW - A 01340:Antibiotics & Antimicrobials KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21506993?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Molecular+Comparison+of+Mycobacterium+avium+Isolates+from+Clinical+and+Environmental+Sources&rft.au=Hilborn%2C+Elizabeth+D%3BYakrus%2C+Mitchell+A%3BCovert%2C+Terry+C%3BHarris%2C+Stephanie+I%3BDonnelly%2C+Sandra+F%3BSchmitt%2C+Michael+T%3BToney%2C+Sean%3BBailey%2C+Stephanie+A%3BStelma+Jr.+Jr%2C+Gerard+N&rft.aulast=Hilborn&rft.aufirst=Elizabeth&rft.date=2008-08-01&rft.volume=74&rft.issue=15&rft.spage=4966&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.02900-07 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Mycobacterium avium DO - http://dx.doi.org/10.1128/AEM.02900-07 ER - TY - JOUR T1 - Impediments and Solutions to Sustainable, Watershed-Scale Urban Stormwater Management: Lessons from Australia and the United States AN - 21274439; 11899329 AB - In urban and suburban areas, stormwater runoff is a primary stressor on surface waters. Conventional urban stormwater drainage systems often route runoff directly to streams and rivers, thus exacerbating pollutant inputs and hydrologic disturbance, and resulting in the degradation of ecosystem structure and function. Decentralized stormwater management tools, such as low impact development (LID) or water sensitive urban design (WSUD), may offer a more sustainable solution to stormwater management if implemented at a watershed scale. These tools are designed to pond, infiltrate, and harvest water at the source, encouraging evaporation, evapotranspiration, groundwater recharge, and re-use of stormwater. While there are numerous demonstrations of WSUD practices, there are few examples of widespread implementation at a watershed scale with the explicit objective of protecting or restoring a receiving stream. This article identifies seven major impediments to sustainable urban stormwater management: (1) uncertainties in performance and cost, (2) insufficient engineering standards and guidelines, (3) fragmented responsibilities, (4) lack of institutional capacity, (5) lack of legislative mandate, (6) lack of funding and effective market incentives, and (7) resistance to change. By comparing experiences from Australia and the United States, two developed countries with existing conventional stormwater infrastructure and escalating stream ecosystem degradation, we highlight challenges facing sustainable urban stormwater management and offer several examples of successful, regional WSUD implementation. We conclude by identifying solutions to each of the seven impediments that, when employed separately or in combination, should encourage widespread implementation of WSUD with watershed-based goals to protect human health and safety, and stream ecosystems. JF - Environmental Management AU - Roy, Allison H AU - Wenger, Seth J AU - Fletcher, Tim D AU - Walsh, Christopher J AU - Ladson, Anthony R AU - Shuster, William D AU - Thurston, Hale W AU - Brown, Rebekah R AD - Office of Research and Development, US Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, OH, 45268, USA, roy.allison@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 344 EP - 359 PB - Springer-Verlag, 175 Fifth Ave. New York NY 10010 USA VL - 42 IS - 2 SN - 0364-152X, 0364-152X KW - Ecology Abstracts; Pollution Abstracts; Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Meteorological & Geoastrophysical Abstracts KW - Ecosystems KW - Evaporation KW - Sustainable development KW - Freshwater KW - Watersheds KW - Ponds KW - Groundwater recharge KW - Stream Pollution KW - Structural Engineering KW - responsibility KW - management tools KW - Rivers KW - River discharge KW - Ecosystem disturbance KW - Water management KW - Urban Runoff KW - Standards KW - Environment management KW - Legislation KW - Runoff KW - developed countries KW - Degradation KW - Financing KW - Surface water KW - Streams KW - Urban planning KW - Pollutants KW - Stormwater runoff KW - guidelines KW - Australia KW - ecosystem structure KW - Urban areas KW - Evapotranspiration KW - USA KW - safety engineering KW - Drainage systems KW - Capacity KW - Q5 08503:Characteristics, behavior and fate KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution KW - Q2 09171:Dynamics of lakes and rivers KW - M2 556.16:Runoff (556.16) KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21274439?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Management&rft.atitle=Impediments+and+Solutions+to+Sustainable%2C+Watershed-Scale+Urban+Stormwater+Management%3A+Lessons+from+Australia+and+the+United+States&rft.au=Roy%2C+Allison+H%3BWenger%2C+Seth+J%3BFletcher%2C+Tim+D%3BWalsh%2C+Christopher+J%3BLadson%2C+Anthony+R%3BShuster%2C+William+D%3BThurston%2C+Hale+W%3BBrown%2C+Rebekah+R&rft.aulast=Roy&rft.aufirst=Allison&rft.date=2008-08-01&rft.volume=42&rft.issue=2&rft.spage=344&rft.isbn=&rft.btitle=&rft.title=Environmental+Management&rft.issn=0364152X&rft_id=info:doi/10.1007%2Fs00267-008-9119-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Financing; Stormwater runoff; Water management; River discharge; Watersheds; Environment management; Runoff; Ponds; Ecosystem disturbance; Drainage systems; Pollutants; Surface water; Evaporation; Streams; Rivers; Groundwater recharge; Evapotranspiration; management tools; Degradation; Sustainable development; Urban planning; safety engineering; guidelines; ecosystem structure; Legislation; developed countries; Urban areas; responsibility; Ecosystems; Stream Pollution; Standards; Urban Runoff; Capacity; Structural Engineering; USA; Australia; Freshwater DO - http://dx.doi.org/10.1007/s00267-008-9119-1 ER - TY - JOUR T1 - Detecting Temporal Change in Watershed Nutrient Yields AN - 21266922; 11899330 AB - Meta-analyses reveal that nutrient yields tend to be higher for watersheds dominated by anthropogenic uses (e.g., urban, agriculture) and lower for watersheds dominated by natural vegetation. One implication of this pattern is that loss of natural vegetation will produce increases in watershed nutrient yields. Yet, the same meta-analyses also reveal that, absent land-cover change, watershed nutrient yields vary from one year to the next due to many exogenous factors. The interacting effects of land cover and exogenous factors suggest nutrient yields should be treated as distributions, and the effect of land-cover change should be examined by looking for significant changes in the distributions. We compiled nutrient yield distributions from published data. The published data included watersheds with homogeneous land cover that typically reported two or more years of annual nutrient yields for the same watershed. These data were used to construct statistical models, and the models were used to estimate changes in the nutrient yield distributions as a result of land-cover change. Land-cover changes were derived from the National Land Cover Database (NLCD). Total nitrogen (TN) yield distributions increased significantly for 35 of 1550 watersheds and decreased significantly for 51. Total phosphorus (TP) yield distributions increased significantly for 142 watersheds and decreased significantly for 17. The amount of land-cover change required to produce significant shifts in nutrient yield distributions was not constant. Small land-cover changes led to significant shifts in nutrient yield distributions when watersheds were dominated by natural vegetation, whereas much larger land-cover changes were needed to produce significant shifts when watersheds were dominated by urban or agriculture. We discuss our results in the context of the Clean Water Act. JF - Environmental Management AU - Wickham, James D AU - Wade, Timothy G AU - Riitters, Kurt H AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency (E243-05), Research Triangle Park, NC, 27711, USA Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 223 EP - 231 PB - Springer-Verlag, 175 Fifth Ave. New York NY 10010 USA VL - 42 IS - 2 SN - 0364-152X, 0364-152X KW - Ecology Abstracts; Pollution Abstracts; Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Environment Abstracts; Water Resources Abstracts; Meteorological & Geoastrophysical Abstracts KW - Agriculture KW - Phosphorus KW - Statistical analysis KW - Anthropogenic factors KW - Nutrients KW - Watersheds KW - Models KW - Yield KW - urban agriculture KW - Statistical Analysis KW - Mathematical models KW - Data processing KW - anthropogenic factors KW - Temporal variations KW - Statistical models KW - agriculture KW - Vegetation KW - Land use KW - Databases KW - natural vegetation KW - Reviews KW - Clean Water Act KW - Nutrients (mineral) KW - Natural vegetation KW - Nitrogen KW - ENA 06:Food & Drugs KW - M2 551.510.42:Air Pollution (551.510.42) KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - Q2 09184:Composition of water KW - SW 3020:Sources and fate of pollution KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21266922?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Management&rft.atitle=Detecting+Temporal+Change+in+Watershed+Nutrient+Yields&rft.au=Wickham%2C+James+D%3BWade%2C+Timothy+G%3BRiitters%2C+Kurt+H&rft.aulast=Wickham&rft.aufirst=James&rft.date=2008-08-01&rft.volume=42&rft.issue=2&rft.spage=223&rft.isbn=&rft.btitle=&rft.title=Environmental+Management&rft.issn=0364152X&rft_id=info:doi/10.1007%2Fs00267-008-9120-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Temporal variations; Statistical models; Anthropogenic factors; Nutrients (mineral); Watersheds; Agriculture; Data processing; Reviews; Statistical analysis; Nutrients; Natural vegetation; Models; Clean Water Act; Mathematical models; anthropogenic factors; natural vegetation; urban agriculture; Phosphorus; agriculture; Land use; Nitrogen; Databases; Yield; Statistical Analysis; Vegetation DO - http://dx.doi.org/10.1007/s00267-008-9120-8 ER - TY - JOUR T1 - The revolution that didn't arrive: A review of Pleistocene Sahul AN - 20917443; 8493647 AB - There is a ''package'' of cultural innovations that are claimed to reflect modern human behaviour. The introduction of the ''package'' has been associated with the Middle-to-Upper Palaeolithic transition and the appearance in Europe of modern humans. It has been proposed that modern humans spread from Africa with the ''package'' and colonised not only Europe but also southern Asia and Australia (McBrearty and Brooks, 2000; Mellars, 2006a). In order to evaluate this proposal, we explore the late Pleistocene archaeological record of Sahul, the combined landmass of Australia and Papua New Guinea, for indications of these cultural innovations at the earliest sites. It was found that following initial occupation of the continent by anatomically and behaviourally modern humans, the components were gradually assembled over a 30,000-year period. We discount the idea that the ''package'' was lost en route to Sahul and assess the possibility that the ''package'' was not integrated within the material culture of the initial colonising groups because they may not have been part of a rapid colonisation process from Africa. As the cultural innovations appear at different times and locations within Sahul, the proposed ''package'' of archaeologically visible traits cannot be used to establish modern human behaviour. Whilst the potential causal role of increasing population densities/pressure in the appearance of the ''package'' of modern human behaviour in the archaeological record is acknowledged, it is not seen as the sole explanation because the individual components of the ''package'' appear at sites that are widely separated in space and time. JF - Journal of Human Evolution AU - Habgood, P J AU - Franklin, N R AD - University of Queensland, Brisbane QLD 4072, Australia, natalie.franklin@epa.qld.gov.au Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 187 EP - 222 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 55 IS - 2 SN - 0047-2484, 0047-2484 KW - Ecology Abstracts KW - Reviews KW - Population density KW - Pressure KW - D 04050:Paleoecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20917443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Human+Evolution&rft.atitle=The+revolution+that+didn%27t+arrive%3A+A+review+of+Pleistocene+Sahul&rft.au=Habgood%2C+P+J%3BFranklin%2C+N+R&rft.aulast=Habgood&rft.aufirst=P&rft.date=2008-08-01&rft.volume=55&rft.issue=2&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Journal+of+Human+Evolution&rft.issn=00472484&rft_id=info:doi/10.1016%2Fj.jhevol.2007.11.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Reviews; Population density; Pressure DO - http://dx.doi.org/10.1016/j.jhevol.2007.11.006 ER - TY - JOUR T1 - Extension and evaluation of sensitivity analysis capabilities in a photochemical model AN - 20816446; 8289396 AB - The decoupled direct method in three dimensions (DDM-3D) provides an efficient and accurate approach for probing the sensitivity of atmospheric pollutant concentrations to various changes in photochemical model inputs. The implementation of DDM-3D for the widely used Community Multiscale Air Quality (CMAQ) model was updated to account for recent changes in the base model and to include additional chemical mechanisms and advection schemes. The capabilities of CMAQ-DDM-3D were extended to enable execution using multiple processors in parallel and the computation of sensitivities to chemical reaction rate constants. The resulting direct sensitivity modeling system was tested for statistical agreement with the traditional difference method for calculating sensitivities, considering a summer episode in a domain covering the continental United States. Sensitivities to domain-wide and sector specific emissions, initial/boundary conditions, and chemical reaction rates were compared and found to be in good correlation for both primary and secondary air pollutants. The scalability of CMAQ-DDM-3D to the number of processors used in parallel was also examined. Sensitivity calculations were found to scale in a similar way to the base model, where the benefit to model runtime of adding more processors diminished for simulations that used more than eight processors. JF - Environmental Modelling & Software AU - Napelenok, S L AU - Cohan, D S AU - Odman, M T AU - Tonse, S AD - Air Resources Laboratory, National Oceanic and Atmospheric Administration, In partnership with the United States Environmental Protection Agency, 109 T.W. Alexander Drive, U.S. EPA, Mail Drop E243-01, Research Triangle Park, NC 27711, USA, napelenok.sergey@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 994 EP - 999 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 23 IS - 8 SN - 1364-8152, 1364-8152 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - Statistical analysis KW - Correlations KW - Air quality KW - Boundary conditions KW - Advection KW - Computer programs KW - sensitivity analysis KW - Atmospheric chemistry models KW - Emissions KW - Atmospheric pollution KW - Simulation KW - advection KW - boundary conditions KW - Air quality models KW - Air pollution KW - USA KW - Photochemicals KW - Sensitivity analysis KW - Numerical simulations KW - Chemical reactions KW - summer KW - Photochemical models KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20816446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Modelling+%26+Software&rft.atitle=Extension+and+evaluation+of+sensitivity+analysis+capabilities+in+a+photochemical+model&rft.au=Napelenok%2C+S+L%3BCohan%2C+D+S%3BOdman%2C+M+T%3BTonse%2C+S&rft.aulast=Napelenok&rft.aufirst=S&rft.date=2008-08-01&rft.volume=23&rft.issue=8&rft.spage=994&rft.isbn=&rft.btitle=&rft.title=Environmental+Modelling+%26+Software&rft.issn=13648152&rft_id=info:doi/10.1016%2Fj.envsoft.2007.11.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution models; Atmospheric pollution; Numerical simulations; Sensitivity analysis; Atmospheric chemistry models; Correlations; Statistical analysis; Air quality; Photochemical models; Boundary conditions; Advection; Air quality models; Air pollution; Computer programs; Photochemicals; Chemical reactions; sensitivity analysis; Emissions; Simulation; summer; advection; boundary conditions; USA DO - http://dx.doi.org/10.1016/j.envsoft.2007.11.004 ER - TY - JOUR T1 - The Role of Catalyst Properties on Methanol Oxidation over V sub(2)O sub(5)-TiO sub(2) Using Ozone AN - 20765104; 8163672 AB - Oxidation of methanol over V sub(2)O sub(5) catalysts supported on anatase TiO sub(2) that were prepared using sol-gel formation and impregnation procedures were investigated. The effects of incorporating Mg in sol-gel to influence the properties of the catalyst were also studied. The process provides an alternative low temperature reaction pathway for reducing emissions of hazardous air pollutant (HAPs) such as methanol and total reduced sulfur compounds (TRS) from pulp and paper mills. The bulk and surface composition of the catalysts were determined by XRD and SEM-EDAX, respectively. The X-ray diffraction patterns of the vanadia-titania catalysts showed mainly the anatase phase of TiO sub(2). Temperature programmed desorption of methanol from the different catalyst showed that the a and b peaks differ significantly with V content and addition of Mg. The combination of gas phase and surface reactions on the V/TiO sub(2) catalysts reduced the amount of ozone required for high degradation of methanol to mainly CO sub(x) with small quantities of methyl formate. In the absence of ozone the catalysts showed very low activity. It is hypothesized that the ozone is directly influencing the V super(4+) and V super(5+) redox cycle of the catalyst. Oxidation of methanol is influenced by the operation variables and catalyst properties. The results of this study revealed that the V content has significant influence on the catalyst activity, and the optimum vanadia loading of about 6 wt%. Higher turnover frequencies were observed over sol-gel catalysts than with catalysts prepared by the impregnation method. JF - Water, Air, & Soil Pollution: Focus AU - Sahle-Demessie, Endalkachew AU - Almquist, Catherine B AU - Sehker, Sridara Chandra AD - US EPA, 26 W. Martin Luther King Drive (MS 443), Cincinnati, OH, 45268, USA, sahle-demessie.endalkachew@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 297 EP - 309 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 8 IS - 3-4 SN - 1567-7230, 1567-7230 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - paper mills KW - Desorption KW - Atmospheric pollution KW - Sulfur in atmosphere KW - Temperature KW - Soil contamination KW - X-ray diffraction KW - Air pollution KW - Low temperatures KW - Soil pollution KW - Sulfur compounds emissions KW - Oxidation KW - Emissions KW - low temperature KW - Catalysts KW - Diffraction KW - Sulfur compounds KW - Ozone KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20765104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water%2C+Air%2C+%26+Soil+Pollution%3A+Focus&rft.atitle=The+Role+of+Catalyst+Properties+on+Methanol+Oxidation+over+V+sub%282%29O+sub%285%29-TiO+sub%282%29+Using+Ozone&rft.au=Sahle-Demessie%2C+Endalkachew%3BAlmquist%2C+Catherine+B%3BSehker%2C+Sridara+Chandra&rft.aulast=Sahle-Demessie&rft.aufirst=Endalkachew&rft.date=2008-08-01&rft.volume=8&rft.issue=3-4&rft.spage=297&rft.isbn=&rft.btitle=&rft.title=Water%2C+Air%2C+%26+Soil+Pollution%3A+Focus&rft.issn=15677230&rft_id=info:doi/10.1007%2Fs11267-007-9145-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Soil pollution; Low temperatures; Atmospheric pollution; Sulfur compounds emissions; Sulfur in atmosphere; Oxidation; Diffraction; Air pollution; paper mills; Desorption; Temperature; low temperature; Emissions; Soil contamination; Catalysts; Sulfur compounds; X-ray diffraction; Ozone DO - http://dx.doi.org/10.1007/s11267-007-9145-7 ER - TY - JOUR T1 - Mercury Capture on Fly Ash and Sorbents: The Effects of Coal Properties and Combustion Conditions AN - 20688191; 8163678 AB - The US fleet of coal-fired power plants, with generating capacity of just over 300 GW, is known to be a major source of domestic mercury (Hg) emissions. To address this, in March 2005, the Environmental Protection Agency (EPA) promulgated the Clean Air Mercury Rule (CAMR) to reduce emissions of mercury from these plants. It is generally believed that most of the initial (Phase I) mercury reductions will come as a co-benefit of existing controls used to remove particulate matter (PM), SO sub(2), and NO sub(x). Deeper reductions in emissions (as required in Phase II of CAMR) may require the installation of mercury-specific control technology. Duct injection of activated carbon sorbents is the mercury-specific control technology that has been most widely studied and has been demonstrated over a wide range of coal types and combustion conditions. The effectiveness of the mercury control options (both 'co-benefit control' and 'mercury-specific control') is significantly impacted by site-specific characteristics such as the combustion conditions, the configuration of existing air pollution controls, and the type of coal burned. This paper identifies the role of coal properties and combustion conditions in the capture of mercury by fly ash and injected sorbents. JF - Water, Air, & Soil Pollution: Focus AU - Hutson, Nick D AD - U. S. Environmental Protection Agency, 109 T. W. Alexander Drive (E305-01), Research Triangle Park, North Carolina, NC, 27711, USA, hutson.nick@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 323 EP - 331 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 8 IS - 3-4 SN - 1567-7230, 1567-7230 KW - Pollution Abstracts KW - Activated carbon KW - Fly ash KW - Air pollution control KW - Particulates KW - Soil contamination KW - Coal KW - Combustion KW - EPA KW - Sorbents KW - Sulfur dioxide KW - Power plants KW - Emissions KW - Mercury KW - Technology KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20688191?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water%2C+Air%2C+%26+Soil+Pollution%3A+Focus&rft.atitle=Mercury+Capture+on+Fly+Ash+and+Sorbents%3A+The+Effects+of+Coal+Properties+and+Combustion+Conditions&rft.au=Hutson%2C+Nick+D&rft.aulast=Hutson&rft.aufirst=Nick&rft.date=2008-08-01&rft.volume=8&rft.issue=3-4&rft.spage=323&rft.isbn=&rft.btitle=&rft.title=Water%2C+Air%2C+%26+Soil+Pollution%3A+Focus&rft.issn=15677230&rft_id=info:doi/10.1007%2Fs11267-007-9151-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Activated carbon; Fly ash; Air pollution control; Coal; Soil contamination; Particulates; Combustion; EPA; Sorbents; Sulfur dioxide; Emissions; Power plants; Mercury; Technology DO - http://dx.doi.org/10.1007/s11267-007-9151-9 ER - TY - JOUR T1 - Prediction of daily flow duration curves and streamflow for ungauged catchments using regional flow duration curves TT - Prevision de courbes de debits classes et de debit fluviatile pour des bassins versants non jauges a l'aide de courbes de debits classes regionales AN - 20254066; 8543218 AB - A method is presented to predict flow duration curves (FDCs) and streamflow for ungauged catchments in the Mid-Atlantic Region, USA. Twenty-nine catchments were selected from the Appalachian Plateau, Ridge and Valley, and Piedmont physiographic provinces to develop and test the proposed method. Using a step-wise multiple regression analysis, the dominant landscape and climate descriptors were identified and regional FDC models were developed for each province. Predictive performance of the proposed method was estimated using data from three evaluation sites that were not included in parameter estimation for the regional FDC models. The results of this study show that climate and geomorphological descriptors strongly influence the hydrology of the Appalachian Plateau and some Ridge and Valley catchments, whereas soil and geomorphological descriptors strongly influence the hydrology of the Piedmont and some Ridge and Valley catchments. Streamflow values calculated by the drainage area ratio method and those reconstructed by the FDC method were compared with the observed streamflow values. The results indicate that the FDC-based method shows great promise for predicting streamflow in ungauged basins. JF - Hydrological Sciences Journal/Journal des Sciences Hydrologiques AU - Mohamoud, Y M AD - USEP A National Exposure Research Laboratory, 960 College Station Road, Athens. Georgia, USA, mohamoud.yusuf@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 706 EP - 724 VL - 53 IS - 4 SN - 0262-6667, 0262-6667 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Environment Abstracts; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts KW - Catchment area KW - Prediction KW - Basins KW - Physiographic Provinces KW - Flow rates KW - Soil KW - Hydrologic Models KW - Geomorphology KW - Catchment basins KW - Flow duration curves KW - Regression analysis KW - Hydrology KW - Topography KW - Climate models KW - Hydrologic analysis KW - valleys KW - Drainage KW - Catchment Areas KW - Climates KW - Climate KW - Streamflow KW - Stream flow KW - Physiographic provinces KW - plateaus KW - ridges KW - Flow Duration KW - Catchments KW - USA, Appalachian Plateau KW - ANW, USA, Mid-Atlantic Region KW - geomorphology KW - Q2 09262:Methods and instruments KW - SW 0835:Streamflow and runoff KW - M2 556.16:Runoff (556.16) KW - ENA 15:Renewable Resources-Terrestrial UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20254066?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Hydrological+Sciences+Journal%2FJournal+des+Sciences+Hydrologiques&rft.atitle=Prediction+of+daily+flow+duration+curves+and+streamflow+for+ungauged+catchments+using+regional+flow+duration+curves&rft.au=Mohamoud%2C+Y+M&rft.aulast=Mohamoud&rft.aufirst=Y&rft.date=2008-08-01&rft.volume=53&rft.issue=4&rft.spage=706&rft.isbn=&rft.btitle=&rft.title=Hydrological+Sciences+Journal%2FJournal+des+Sciences+Hydrologiques&rft.issn=02626667&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Physiographic provinces; Prediction; Catchment area; Geomorphology; Climate; Hydrology; Stream flow; Hydrologic analysis; Climate models; Flow duration curves; Catchment basins; Drainage; Regression analysis; Topography; Soil; plateaus; ridges; valleys; Catchments; Basins; geomorphology; Flow rates; Hydrologic Models; Flow Duration; Climates; Catchment Areas; Streamflow; Physiographic Provinces; USA, Appalachian Plateau; ANW, USA, Mid-Atlantic Region ER - TY - JOUR T1 - Effects of Exposure to 0.06 ppm Ozone on FEV sub(1) in Humans: A Secondary Analysis of Existing Data AN - 20253799; 8399802 AB - Background: Ozone is a potent photochemical oxidant that produces transient, reversible decrements in the lung function of acutely exposed individuals. A recent study provided previously unavailable clinical data for 30 healthy young adults exposed to O sub(3) at 0.06 ppm. That study showed significant effects of 0.08 ppm on lung function, confirming the findings of others. However, exposure to 0.06 ppm O sub(3) was not reported to significantly affect lung function. Objectives: We conducted this analysis to reevaluate the existing lung function data of the volunteers previously exposed to 0.06 ppm O sub(3). Methods: We obtained pre- and postexposure data on forced expiratory volume in 1 sec (FEV sub(1)) for all subjects who were previously exposed for 6.6 hr to filtered air or to 0.06 ppm or 0.08 ppm O sub(3). We used standard statistical methods appropriate for paired comparisons to reanalyze FEV sub(1) responses after exposure to 0.06 ppm O sub(3) relative to filtered air. Results: Controlling for filtered air responses, 24 of the 30 subjects experienced an O sub(3)-induced decrement in FEV sub(1). On average, 0.06 ppm O sub(3) exposure caused a 2.85% reduction in FEV sub(1) (p 10% FEV sub(1) decrements. Conclusions: Exposure to 0.06 ppm O sub(3) causes a biologically small but highly statistically significant decrease in mean FEV sub(1) responses of young healthy adults. JF - Environmental Health Perspectives AU - Brown, J S AU - Bateson, T F AU - McDonnell, W F AD - U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, B243-01, Research Triangle Park, NC 27711 USA, Brown.James@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 1023 EP - 1026 VL - 116 IS - 8 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts; Health & Safety Science Abstracts; Environment Abstracts; Pollution Abstracts KW - Data processing KW - Statistics KW - Statistical analysis KW - Pollution effects KW - young adults KW - Models KW - Air pollution KW - Photochemicals KW - secondary analysis KW - Lung KW - Respiratory function KW - Oxidants KW - Ozone KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24300:Methods KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20253799?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Effects+of+Exposure+to+0.06+ppm+Ozone+on+FEV+sub%281%29+in+Humans%3A+A+Secondary+Analysis+of+Existing+Data&rft.au=Brown%2C+J+S%3BBateson%2C+T+F%3BMcDonnell%2C+W+F&rft.aulast=Brown&rft.aufirst=J&rft.date=2008-08-01&rft.volume=116&rft.issue=8&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.11396 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Statistics; Data processing; Lung; Statistical analysis; Oxidants; Models; Ozone; Air pollution; Photochemicals; secondary analysis; Pollution effects; Respiratory function; young adults DO - http://dx.doi.org/10.1289/ehp.11396 ER - TY - JOUR T1 - In Situ Source Treatment of Cr(VI) Using a Fe(II)-Based Reductant Blend: Long-Term Monitoring and Evaluation AN - 20234693; 8397648 AB - The long-term effectiveness of an FeSO sub(4)+Na sub(2)S sub(2)O sub(4) reductant solution blend for in situ saturated zone treatment of dissolved and solid phase Cr(VI) in a high pH chromite ore processing solid waste fill material was investigated. Two field pilot injection studies were conducted that showed sustained treatment of Cr(VI) over evaluation periods of more than 1,000 days. No well or aquifer formation clogging was observed during injection although treatment was limited to the pore volume displacement radius of the injected reductant. Analysis of posttreatment core samples suggested >85% treatment effectiveness of solid phase Cr(VI), whereas lab tests suggested treatment of the solid phase Cr(VI) can be complete provided the chromite ore processing solid waste sediments are sufficiently dosed with the reductant. The sustained treatment of dissolved phase Cr(VI) migrating through the treatment zones for more than 1,000 days following injection provided strong evidence of a residual treatment capacity having been imparted to the formation solids. Scanning electron microscopy--energy dispersive x-ray spectroscopy analyses of posttreatment core samples indicated that much of the Cr(VI) may be removed through the formation of a Cr-bearing precipitate, possibly a complex carbonate, characterized by an Fe:Cr molar ratio of roughly 1:1. JF - Journal of Environmental Engineering AU - Ludwig, R D AU - Su, C AU - Lee, T R AU - Wilkin, R T AU - Sass, B M AD - National Risk Management Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, 919 Kerr Research Dr, Ada, OK 74820, USA, ludwig.ralph@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 651 EP - 658 VL - 134 IS - 8 SN - 0733-9372, 0733-9372 KW - Environment Abstracts KW - Aquifers KW - solid wastes KW - Chromium KW - X-ray spectroscopy KW - Sediments KW - pH KW - ENA 17:Waste Management-Solid UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20234693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Engineering&rft.atitle=In+Situ+Source+Treatment+of+Cr%28VI%29+Using+a+Fe%28II%29-Based+Reductant+Blend%3A+Long-Term+Monitoring+and+Evaluation&rft.au=Ludwig%2C+R+D%3BSu%2C+C%3BLee%2C+T+R%3BWilkin%2C+R+T%3BSass%2C+B+M&rft.aulast=Ludwig&rft.aufirst=R&rft.date=2008-08-01&rft.volume=134&rft.issue=8&rft.spage=651&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Engineering&rft.issn=07339372&rft_id=info:doi/10.1061%2F%28ASCE%290733-9372%282008%29134%3A8%28651%29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Aquifers; solid wastes; Chromium; X-ray spectroscopy; pH; Sediments DO - http://dx.doi.org/10.1061/(ASCE)0733-9372(2008)134:8(651) ER - TY - JOUR T1 - A Technical Example of Treatment for Urban Wastewater Reused in Circulating Cooling Water System in Power Stations AN - 20052176; 8832125 AB - After advanced lime treatment, urban wastewater can be reused as the complement of cooling water in power stations. Lime processing technique is enriched with such advantages as low operating cost, little environmental pollution, no discharge of soluble salt, no pollution to natural body of water. Its solid waste is easy to dispose and there is a reduction of the content of organic compounds, silicide and ferrum etc, in the lime - treated water. The technique has the features of long operating life, small maintenance workload, mature techique and low investment. Through advanced lime treatment, urban waste water can be safely reused in thermal power station's circulating cooling water system. JF - Environmental Science and Management AU - Dai, J AU - Zheng, M AD - EPA Pizhou, Pizhou 221300, China Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 108 EP - 111 PB - China Journal, [mailto:bfhj@vip.163.com], [URL:http://bfhj.chinajournal.net.cn] VL - 33 IS - 8 SN - 1673-1212, 1673-1212 KW - Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Thermal Power KW - Cooling water KW - Wastewater treatment KW - working conditions KW - operating costs KW - Cooling Water KW - Power plants KW - Investment KW - solid wastes KW - Operating Costs KW - Lime KW - Maintenance KW - Salts KW - Organic Compounds KW - Wastewater Treatment KW - P 3000:SEWAGE & WASTEWATER TREATMENT KW - AQ 00006:Sewage KW - SW 3040:Wastewater treatment processes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20052176?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+and+Management&rft.atitle=A+Technical+Example+of+Treatment+for+Urban+Wastewater+Reused+in+Circulating+Cooling+Water+System+in+Power+Stations&rft.au=Dai%2C+J%3BZheng%2C+M&rft.aulast=Dai&rft.aufirst=J&rft.date=2008-08-01&rft.volume=33&rft.issue=8&rft.spage=108&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+and+Management&rft.issn=16731212&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Salts; solid wastes; Cooling water; Power plants; Wastewater treatment; Lime; operating costs; Maintenance; working conditions; Cooling Water; Thermal Power; Organic Compounds; Investment; Operating Costs; Wastewater Treatment ER - TY - JOUR T1 - Effects of erosion and macroalgae on intertidal eelgrass (Zostera marina) in a northeastern Pacific estuary (USA) AN - 19684191; 8496059 AB - Eelgrass (Zostera marina) in open-coast northeastern Pacific estuaries is primarily intertidal, yet little research has been done on the natural factors controlling its upper intertidal growth limits. This two-year study in the Yaquina Estuary (Newport, Oregon, USA) evaluated the effects of two factors (erosion and macroalgal accumulations) on populations of eelgrass. Six study sites were located on steep (n=3) and shallow (n=3) intertidal slopes. At each site, triplicate plots (9ANBm) were placed at five tidal elevations. In the plots, we counted shoots monthly into three categories: vegetative, reproductive, or seedling. Canopy height, blade width, blades per shoot, macroalgal biomass, and an index of erosion were also measured. Yaquina Estuary eelgrass behaves as a perennial in the lower intertidal zone and as an annual in the upper intertidal zone. In the transition between the low and high intertidal zones, there are both perennial (in patches) and annual forms. We suggest that aerial desiccation, macroalgae, and erosion play a role in controlling intertidal eelgrass and that these factors operate in an acute rather than a chronic manner. JF - Botanica Marina AU - Boese, Bruce L AU - Robbins, Bradley D AD - U.S. Environmental Protection Agency, Pacific Coastal Ecology Branch, 2111 SE Marine Science Dr., Newport, OR 97365, USA, boese.bruce@epa.gov Y1 - 2008/08/01/ PY - 2008 DA - 2008 Aug 01 SP - 247 EP - 257 PB - Walter de Gruyter und Co., Genthiner Str. 13 VL - 51 IS - 4 SN - 0006-8055, 0006-8055 KW - Ecology Abstracts; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Sustainability Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Water Resources Abstracts KW - INE, USA, Oregon, Yaquina Estuary KW - Growth KW - Marine plants (see also marine algae, seaweeds) KW - shoots KW - Desiccation KW - Canopies KW - Slopes KW - Canopy KW - Algae KW - Marine KW - Marinas KW - Estuaries KW - Brackish KW - Drying KW - Biomass KW - desiccation KW - Intertidal environment KW - Shoots KW - INE, USA, Oregon KW - Erosion KW - Tidal range KW - Elevation KW - Seedlings KW - Sea grass KW - Zostera marina KW - canopies KW - O 1070:Ecology/Community Studies KW - M3 1010:Issues in Sustainable Development KW - SW 0870:Erosion and sedimentation KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08423:Behaviour KW - K 03450:Ecology KW - Q5 08501:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19684191?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Botanica+Marina&rft.atitle=Effects+of+erosion+and+macroalgae+on+intertidal+eelgrass+%28Zostera+marina%29+in+a+northeastern+Pacific+estuary+%28USA%29&rft.au=Boese%2C+Bruce+L%3BRobbins%2C+Bradley+D&rft.aulast=Boese&rft.aufirst=Bruce&rft.date=2008-08-01&rft.volume=51&rft.issue=4&rft.spage=247&rft.isbn=&rft.btitle=&rft.title=Botanica+Marina&rft.issn=00068055&rft_id=info:doi/10.1515%2FBOT.2008.034 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Growth; Tidal range; Estuaries; Sea grass; Canopies; Desiccation; Intertidal environment; Shoots; Seedlings; Biomass; Erosion; shoots; desiccation; canopies; Marine plants (see also marine algae, seaweeds); Marinas; Elevation; Drying; Slopes; Canopy; Algae; Zostera marina; INE, USA, Oregon; INE, USA, Oregon, Yaquina Estuary; Marine; Brackish DO - http://dx.doi.org/10.1515/BOT.2008.034 ER - TY - JOUR T1 - Mold species in dust from the International Space Station identified and quantified by mold-specific quantitative PCR AN - 19648351; 8535446 AB - Dust was collected over a period of several weeks in 2007 from HEPA filters in the U.S. Laboratory Module of the International Space Station (ISS). The dust was returned on the Space Shuttle Atlantis, mixed, sieved and the DNA was extracted. Using a DNA-based method called mold-specific quantitative PCR (MSQPCR), 39 molds were measured in the dust. Potential opportunistic pathogens Aspergillus flavus and Aspergillus niger and potential moderate toxin producers Penicillium chrysogenum and Penicillium brevicompactum were noteworthy. No cells of the potential opportunistic pathogens Aspergillus fumigatus, Aspergillus terreus, Fusarium solani or Candida albicans were detected. JF - Research in Microbiology AU - Vesper, S J AU - Wong, W AU - Kuo, C M AU - Pierson, D L AD - United States (US) Environmental Protection Agency, 26 West M.L. King Avenue, M.L. 314, Cincinnati, OH 45268, USA, vesper.stephen@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 432 EP - 435 PB - Editions Scientifiques et Medicales Elsevier, 23 rue Linois 75724 Paris cedex 15 France, [URL:http://www.elsevier.fr] VL - 159 IS - 6 SN - 0923-2508, 0923-2508 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Aspergillus flavus KW - Penicillium brevicompactum KW - Penicillium chrysogenum KW - Molds KW - Candida albicans KW - Pathogens KW - Dust KW - Toxins KW - Filters KW - Aspergillus fumigatus KW - Polymerase chain reaction KW - Aspergillus terreus KW - Aspergillus niger KW - Fusarium solani KW - K 03330:Biochemistry KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19648351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Research+in+Microbiology&rft.atitle=Mold+species+in+dust+from+the+International+Space+Station+identified+and+quantified+by+mold-specific+quantitative+PCR&rft.au=Vesper%2C+S+J%3BWong%2C+W%3BKuo%2C+C+M%3BPierson%2C+D+L&rft.aulast=Vesper&rft.aufirst=S&rft.date=2008-08-01&rft.volume=159&rft.issue=6&rft.spage=432&rft.isbn=&rft.btitle=&rft.title=Research+in+Microbiology&rft.issn=09232508&rft_id=info:doi/10.1016%2Fj.resmic.2008.06.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Filters; Polymerase chain reaction; Molds; Pathogens; Toxins; Dust; Aspergillus flavus; Penicillium brevicompactum; Aspergillus fumigatus; Penicillium chrysogenum; Candida albicans; Aspergillus terreus; Aspergillus niger; Fusarium solani DO - http://dx.doi.org/10.1016/j.resmic.2008.06.001 ER - TY - JOUR T1 - Serum Supplementation Modulates the Effects of Dibutyltin on Human Natural Killer Cell Function AN - 19599422; 8408053 AB - Natural killer (NK) cells are a subset of lymphocytes capable of killing tumor cells, virally infected cells and antibody-coated cells. Dibutyltin (DBT) dichloride is an organotin used as a stabilizer in polyvinylchloride (PVC) plastics and as a deworming product in poultry. DBT may leach from PVC water supply pipes and therefore poses a potential risk to human health. We previously reported diminished NK cells lysis of tumor cells following exposure to DBT in serum-free cell culture medium. However, under in vivo conditions, circulating cells will be exposed to DBT in the presence of 100% plasma; thus we investigated whether serum supplementation and incubation time modulates DBT effects on NK cell killing and the accumulation of DBT in freshly isolated NK cells, to determine whether a serum-free model accurately predicts possible effects of DBT on human NK cells under in vivo conditions. Lytic function was decreased by approximately 35% at an intracellular DBT (DBTi) concentration of 200kM and nearly complete loss of lytic function was observed at DBTi above 300kM for one h. However, an intracellular concentration of 50kM DBT, achieved over 24 h of exposure in 50% serum, reduced lytic function by 50%. Thus, conditions that reflect prolonged contact with circulating DBT, in the presence of serum, suggest that NK cell activity is decreased at lower DBTi. These data indicate that the model is useful in predicting potential human effects of relatively low DBTi concentrations. JF - Fundamental and Applied Toxicology AU - Whalen, Margaret M AU - DeWitt, Jamie C AU - Luebke, Robert W AD - Department of Chemistry, Tennessee State University, Nashville, Tennessee 37209. Curriculum in Toxicology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599. Immunotoxicology Branch, Immunotoxicology Branch, Expaerimental Toxicology Division, NHEERL, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27709 Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 312 EP - 319 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 104 IS - 2 SN - 0272-0590, 0272-0590 KW - Virology & AIDS Abstracts; Immunology Abstracts; Toxicology Abstracts KW - Dibutyltin KW - Poultry KW - Data processing KW - Organotin KW - Natural killer cells KW - Cell culture KW - Lymphocytes KW - Plastics KW - Tumor cells KW - Water supplies KW - Supplementation KW - F 06955:Immunomodulation & Immunopharmacology KW - X 24360:Metals KW - V 22370:Oncology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19599422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fundamental+and+Applied+Toxicology&rft.atitle=Serum+Supplementation+Modulates+the+Effects+of+Dibutyltin+on+Human+Natural+Killer+Cell+Function&rft.au=Whalen%2C+Margaret+M%3BDeWitt%2C+Jamie+C%3BLuebke%2C+Robert+W&rft.aulast=Whalen&rft.aufirst=Margaret&rft.date=2008-08-01&rft.volume=104&rft.issue=2&rft.spage=312&rft.isbn=&rft.btitle=&rft.title=Fundamental+and+Applied+Toxicology&rft.issn=02720590&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-09-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Dibutyltin; Poultry; Organotin; Data processing; Natural killer cells; Cell culture; Plastics; Lymphocytes; Water supplies; Tumor cells; Supplementation ER - TY - JOUR T1 - Influence of trace metal distribution on its leachability from coal fly ash AN - 19488483; 8563060 AB - The risks associated with the reuse of coal fly ash in natural environmental settings in terms of their mobility and ecotoxicological significance is largely determined by: (1) the physicochemical conditions the fly ash is placed under; (2) the total leachable metal content in fly ash and; (3) the distribution or mineralogical fractionation of metals. In this study, we report the mobility of As, Cr, Pb, Fe, Cu and Zn from a single Class F fly ash (CFFA). The influence of pH on metal release was compared to the total leachable metal content, as determined by single and sequential chemical extractions. The results show that the CFFA sample is environmentally safe under natural pH conditions, with metal leaching less than the mandated RCRA limits. The elements Fe, Pb and Cr were moderately soluble at acidic pH and sparingly soluble beyond neutral pH. Arsenic release from CFFA was higher under aggressive pH conditions (pH 9) and consistent with its oxyanionic behavior. Partial dissolution of the acid soluble (exchangeable) fraction at acidic pH; desorption of oxyanions at alkaline pH; adsorption and or co-precipitation of metals with iron (hydr) oxides at neutral pH appeared to be the probable mechanisms controlling metal release. While simple EDTA extractions provided good indications of the total leachable amounts, a direct correlation with pH leaching data was impossible as the mineralogical distribution of the metals in the fly ash appeared to play a significant role in their leachability. In the case of Class F fly ash, metal association with Fe-oxide appeared to play a more dominant role in metal release. JF - Fuel AU - Jegadeesan, G AU - Al-Abed, Souhail R AU - Pinto, Patricio AD - Pegasus Technical Services, Inc., 46 E. Hollister Street, Cincinnati, OH 45219, USA, al-abed.souhail@epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 1887 EP - 1893 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 87 IS - 10-11 SN - 0016-2361, 0016-2361 KW - Pollution Abstracts KW - Mobility KW - Coal KW - Lead KW - Waste management KW - Government regulations KW - pH KW - Metals KW - Federal regulations KW - Desorption KW - Leaching KW - chemical extraction KW - Environmental regulations KW - Physicochemical properties KW - Fly ash KW - Precipitation KW - Fractionation KW - trace metals KW - Iron KW - Legislation KW - Hazardous wastes KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19488483?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fuel&rft.atitle=Influence+of+trace+metal+distribution+on+its+leachability+from+coal+fly+ash&rft.au=Jegadeesan%2C+G%3BAl-Abed%2C+Souhail+R%3BPinto%2C+Patricio&rft.aulast=Jegadeesan&rft.aufirst=G&rft.date=2008-08-01&rft.volume=87&rft.issue=10-11&rft.spage=1887&rft.isbn=&rft.btitle=&rft.title=Fuel&rft.issn=00162361&rft_id=info:doi/10.1016%2Fj.fuel.2007.12.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Precipitation; pH; Metals; Fly ash; Lead; Coal; Mobility; Leaching; Hazardous wastes; Waste management; Legislation; Environmental regulations; trace metals; Government regulations; Iron; Fractionation; chemical extraction; Physicochemical properties; Desorption; Federal regulations DO - http://dx.doi.org/10.1016/j.fuel.2007.12.007 ER - TY - JOUR T1 - Regulation of eutrophication susceptibility in oligohaline regions of a northern Gulf of Mexico estuary, Mobile Bay, Alabama AN - 19474578; 8378721 AB - The factors regulating the eutrophication susceptibility of seven oligohaline regions in the sub-estuaries of Mobile Bay, Alabama were examined in a comparative analysis. The oligohaline regions differed primarily by the dominant land-use of their upstream watersheds, with two of the regions being primarily urban, two being primarily agricultural, and three being primarily forested. A stepwise model selection procedure was used to determine a suite of multiple regression models describing eutrophication response, in terms of a chlorophyll a (chla) on a sampling event basis, in relation to estuarine mixing time scales, nutrient concentrations, light availability, and watershed delivery of freshwater and nutrients. The models indicated a strong positive relationship between chla and mixing time scales (i.e., residence time or freshwater flushing time). Mixing time scales longer than five days allowed maximum chla (64kgl super(-) super(1)), while lowest chla (<1kgl super(-) super(1)) occurred when mixing time scales were less than two days. Of the watershed inputs, chla exhibited opposing relationships with the components of freshwater load, having a negative relationship with discharge and a positive relationship with incoming freshwater nitrogen concentrations. Estuarine phosphorus concentrations and photosynthetically active radiation were also found to be good descriptors of chla. The comparative approach employed here allowed for the development of empirical models that were used to determine the nutrient concentration reductions required to achieve a trophic state of <20kgl super(-) super(1) chla. The average reductions in nitrogen and phosphorus needed to achieve this trophic state ranged from 0 to 32%. JF - Marine Pollution Bulletin AU - Lehrter, J C AD - University of Alabama, 101 Bienville Boulevard, Dauphin Island, AL 36528, USA, lehrter.john@epa.gov Y1 - 2008/08// PY - 2008 DA - August 2008 SP - 1446 EP - 1460 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 56 IS - 8 SN - 0025-326X, 0025-326X KW - Aqualine Abstracts; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Chlorophyll KW - Eutrophication KW - Residence time KW - nutrient concentrations KW - Phosphorus KW - ASW, USA, Alabama, Mobile Bay KW - Nutrients KW - Watersheds KW - Mixing KW - upstream KW - Seawater pollution KW - Sampling KW - Photosynthetically active radiation KW - Regression models KW - Estuaries KW - Brackish KW - Land use KW - Model Studies KW - ASW, Mexico Gulf KW - Marine pollution KW - Flushing time KW - Flushing KW - Nitrogen KW - Estuarine mixing KW - Q5 08503:Characteristics, behavior and fate KW - SW 3010:Identification of pollutants KW - M2 551.468:Coastal Oceanography (551.468) KW - P 1000:MARINE POLLUTION KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19474578?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Pollution+Bulletin&rft.atitle=Regulation+of+eutrophication+susceptibility+in+oligohaline+regions+of+a+northern+Gulf+of+Mexico+estuary%2C+Mobile+Bay%2C+Alabama&rft.au=Lehrter%2C+J+C&rft.aulast=Lehrter&rft.aufirst=J&rft.date=2008-08-01&rft.volume=56&rft.issue=8&rft.spage=1446&rft.isbn=&rft.btitle=&rft.title=Marine+Pollution+Bulletin&rft.issn=0025326X&rft_id=info:doi/10.1016%2Fj.marpolbul.2008.04.047 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Marine pollution; Residence time; Eutrophication; Estuaries; Flushing time; Watersheds; Regression models; Seawater pollution; Photosynthetically active radiation; Land use; Estuarine mixing; upstream; Chlorophyll; Phosphorus; nutrient concentrations; Nitrogen; Flushing; Nutrients; Sampling; Mixing; Model Studies; ASW, Mexico Gulf; ASW, USA, Alabama, Mobile Bay; Brackish DO - http://dx.doi.org/10.1016/j.marpolbul.2008.04.047 ER - TY - JOUR T1 - Sticky Prices and Indeterminacy AN - 19374555; 8395891 AB - The aim of this paper is to analyze the link between price rigidity and indeterminacy. This is done within a cash-in-advance economy that is known to exhibit indeterminacy at high degrees of relative risk aversion. My findings show that price stickiness reduces the scope of these sunspot equilibria: to be compatible with indeterminacy, sluggish price adjustment requires degrees of relative risk aversion that prove too high to square with data. JF - Journal of Money, Credit and Banking AU - Weder, Mark AD - Mark Wederis from the School of Economics, University of Adelaide, Adelaide SA 5005, Australia, CDMA, CAMA, NCER, and CEPR (E-mail: Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 1073 EP - 1082 PB - Ohio State University Press, 180 Pressey Hall VL - 40 IS - 5 SN - 0022-2879, 0022-2879 KW - Risk Abstracts KW - Risk aversion KW - Finance KW - Credit risk KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19374555?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Money%2C+Credit+and+Banking&rft.atitle=Sticky+Prices+and+Indeterminacy&rft.au=Weder%2C+Mark&rft.aulast=Weder&rft.aufirst=Mark&rft.date=2008-08-01&rft.volume=40&rft.issue=5&rft.spage=1073&rft.isbn=&rft.btitle=&rft.title=Journal+of+Money%2C+Credit+and+Banking&rft.issn=00222879&rft_id=info:doi/10.1111%2Fj.1538-4616.2008.00147.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Finance; Credit risk; Risk aversion DO - http://dx.doi.org/10.1111/j.1538-4616.2008.00147.x ER - TY - JOUR T1 - NATO science for peace and security program AN - 19304727; 8408160 JF - Clean Technologies and Environmental Policy AU - Sikdar, Subhas K AD - National Risk Management Research Lab/USEPA, 26 W. M.L. King Dr., Cincinnati, OH, 45268, USA, Sikdar.Subhas@epamail.epa.gov Y1 - 2008/08// PY - 2008 DA - Aug 2008 SP - 221 EP - 222 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 10 IS - 3 SN - 1618-954X, 1618-954X KW - Sustainability Science Abstracts KW - security KW - Environmental policy KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19304727?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clean+Technologies+and+Environmental+Policy&rft.atitle=NATO+science+for+peace+and+security+program&rft.au=Sikdar%2C+Subhas+K&rft.aulast=Sikdar&rft.aufirst=Subhas&rft.date=2008-08-01&rft.volume=10&rft.issue=3&rft.spage=221&rft.isbn=&rft.btitle=&rft.title=Clean+Technologies+and+Environmental+Policy&rft.issn=1618954X&rft_id=info:doi/10.1007%2Fs10098-008-0160-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Environmental policy; security DO - http://dx.doi.org/10.1007/s10098-008-0160-9 ER - TY - JOUR T1 - Assessment of Polybrominated Diphenyl Ether Exposures and Health Risks Associated with Consumption of Southern Mississippi Catfish AN - 754543437; 13266137 AB - Despite the growing public interest in polybrominated diphenyl ethers (PBDEs), there are relatively few studies in the published literature which characterize and quantify human intake of these compounds. In this study, PBDE concentrations were measured in southern Mississippi catfish to determine background levels, daily intake, and risk associated with the consumption of these chemicals from a primary food source for residents in this region of the United States. A total of 33 wild catfish samples were collected from five sites, and 28 farm-raised catfish samples were purchased, all of which were from locations in southern Mississippi. All samples were analyzed for 43 PBDEs (mono- through deca-congeners) using high-resolution gas chromatography-mass spectrometry. Both PBDE concentrations (*SPBDE ranged from 0.3 to 23.3 ng/g wet weight) and congener profiles varied by fish type and location; however, BDE congeners 47, 99, 100, 153, and 154 were the dominant contributors in all samples. The estimated daily intake of PBDEs associated with consumption of the catfish ranged from 0.03 to 1.80 ng/kg-day. Evaluation of the cancer risk for BDE 209 and the noncancer hazard for BDE congeners 47, 99, 153, and 209 indicated that health risks/hazards due to fish consumption in adults are substantially lower than risk levels generally considered to be at the U.S. EPA minimum concern level. JF - Environmental Science & Technology AU - Staskal, Daniele F AU - Scott, Laura L F AU - Haws, Laurie C AU - Luksemburg, William J AU - Birnbaum, Linda S AU - Urban, Jon D AU - Williams, E Spencer AU - Paustenbach, Dennis J AU - Harris, Mark A AD - ChemRisk, Austin, Texas, ChemRisk, Houston, Texas, Vista Analytical Laboratory, El Dorado Hills, California, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, and ChemRisk, San Francisco, California Y1 - 2008/07/30/ PY - 2008 DA - 2008 Jul 30 SP - 6755 EP - 6761 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 17 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; Risk Abstracts; Environment Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Risk assessment KW - Chemicals KW - Food contamination KW - Brominated hydrocarbons KW - Cancer KW - Risks KW - Public health KW - Spectrometry KW - Polybrominated diphenyl ethers KW - Hazards KW - EPA KW - polybrominated diphenyl ethers KW - Fish consumption KW - USA, Mississippi KW - Fish KW - Seafood KW - Public concern KW - ENA 06:Food & Drugs KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - Q5 08501:General KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754543437?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Assessment+of+Polybrominated+Diphenyl+Ether+Exposures+and+Health+Risks+Associated+with+Consumption+of+Southern+Mississippi+Catfish&rft.au=Staskal%2C+Daniele+F%3BScott%2C+Laura+L+F%3BHaws%2C+Laurie+C%3BLuksemburg%2C+William+J%3BBirnbaum%2C+Linda+S%3BUrban%2C+Jon+D%3BWilliams%2C+E+Spencer%3BPaustenbach%2C+Dennis+J%3BHarris%2C+Mark+A&rft.aulast=Staskal&rft.aufirst=Daniele&rft.date=2008-07-30&rft.volume=42&rft.issue=17&rft.spage=6755&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes800613k LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Hazards; Fish consumption; Brominated hydrocarbons; Risks; Chemicals; Risk assessment; Polybrominated diphenyl ethers; EPA; polybrominated diphenyl ethers; Fish; Seafood; Food contamination; Public concern; Cancer; Spectrometry; Public health; USA, Mississippi DO - http://dx.doi.org/10.1021/es800613k ER - TY - JOUR T1 - Protein biomarkers associated with growth and synaptogenesis in a cell culture model of neuronal development AN - 19689128; 8353639 AB - Cerebellar granule cells (CGC) provide a homogenous population of cells which can be used as an in vitro model for studying the cellular processes involved in the normal development of the CNS. They may also be useful for hazard identification as in vitro screens for developmental neurotoxicity. The present study examined morphologic and biochemical markers of CGC neurite outgrowth and synaptogenesis in vitro using both qualitative and quantitative approaches. CGC exhibit a rapid outgrowth of neurites over 14 days in vitro, concomitant with the expression of the synaptic protein Synapsin 1 that was observed as puncta associated with cell bodies and neurites. The expression of neurotypic proteins associated with the cytoskeleton (NF68, MAP2), growth cones (GAP-43) and the synapse (Synapsin I) present an ontogeny that reflects the morphological growth of CGC. The utility of these neurotypic proteins as biomarkers was examined by inhibiting CGC growth using pharmacologic inhibitors of PKC activity and the MAP kinase pathway. Quantitative analysis of neurite outgrowth was performed using an automated image acquisition and analysis system. Treatment of CGC with the MAP kinase pathway inhibitor U0126 significantly decreased total neurite outgrowth, while the inhibitor of classic PKC isoforms Bis I had no effect on this measure. The ontogenetic expression of neurotypic proteins was reduced after treatment with both inhibitors. In particular, Synapsin 1 and GAP-43 expression were both significantly reduced by chemical treatment. These data demonstrate that neurotypic proteins can be used as biomarkers of neuronal development in vitro, and in some cases, may detect changes that are not apparent using morphologic measures. JF - Toxicology AU - Mundy, W R AU - Robinette, B AU - Radio, N M AU - Freudenrich, T M AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA, mundy.william@epa.gov Y1 - 2008/07/30/ PY - 2008 DA - 2008 Jul 30 SP - 220 EP - 229 PB - Elsevier Science, P.O. Box 85 Limerick Ireland VL - 249 IS - 2-3 SN - 0300-483X, 0300-483X KW - Biotechnology and Bioengineering Abstracts; CSA Neurosciences Abstracts; Toxicology Abstracts KW - Protein kinase C KW - Central nervous system KW - MAP kinase KW - Biochemical markers KW - Data processing KW - Growth cones KW - Cerebellum KW - Synapsin I KW - Cell culture KW - biomarkers KW - Granule cells KW - Cytoskeleton KW - GAP-43 protein KW - Synaptogenesis KW - Neurotoxicity KW - Cell body KW - Ontogeny KW - Axonogenesis KW - X 24310:Pharmaceuticals KW - N3 11028:Neuropharmacology & toxicology KW - W 30945:Fermentation & Cell Culture UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19689128?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Protein+biomarkers+associated+with+growth+and+synaptogenesis+in+a+cell+culture+model+of+neuronal+development&rft.au=Mundy%2C+W+R%3BRobinette%2C+B%3BRadio%2C+N+M%3BFreudenrich%2C+T+M&rft.aulast=Mundy&rft.aufirst=W&rft.date=2008-07-30&rft.volume=249&rft.issue=2-3&rft.spage=220&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2008.05.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Protein kinase C; Central nervous system; Biochemical markers; MAP kinase; Data processing; Cerebellum; Growth cones; Synapsin I; Cell culture; biomarkers; Cytoskeleton; Granule cells; GAP-43 protein; Synaptogenesis; Cell body; Neurotoxicity; Axonogenesis; Ontogeny DO - http://dx.doi.org/10.1016/j.tox.2008.05.012 ER - TY - CPAPER T1 - The Effluent Limitations Guidelines and NPDES Permit Regulations for CAFOs: Status of Implementation, Coordination with USDA, and Response to the 2nd Circuit Court Decision T2 - 2008 Annual Conference of the Soil and Water Conservation Society (SWCS 2008) AN - 41058484; 4910692 JF - 2008 Annual Conference of the Soil and Water Conservation Society (SWCS 2008) AU - Wiedeman, Allison Y1 - 2008/07/26/ PY - 2008 DA - 2008 Jul 26 KW - Permits KW - Guidelines KW - Effluents KW - Courts KW - Circuits KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41058484?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2008%29&rft.atitle=The+Effluent+Limitations+Guidelines+and+NPDES+Permit+Regulations+for+CAFOs%3A+Status+of+Implementation%2C+Coordination+with+USDA%2C+and+Response+to+the+2nd+Circuit+Court+Decision&rft.au=Wiedeman%2C+Allison&rft.aulast=Wiedeman&rft.aufirst=Allison&rft.date=2008-07-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://spreadsheets.google.com/pub?key=pIk8xgUTyLUGMJGwArtdDGw LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Science Reassessment of Hypoxia in the Gulf of Mexico and Actions Needed to Reduce Nutrient Loads to the Gulf T2 - 2008 Annual Conference of the Soil and Water Conservation Society (SWCS 2008) AN - 41053246; 4910646 JF - 2008 Annual Conference of the Soil and Water Conservation Society (SWCS 2008) AU - Greene, Rick AU - David, Mark AU - McKenna, Dennis P Y1 - 2008/07/26/ PY - 2008 DA - 2008 Jul 26 KW - Mexico Gulf KW - Hypoxia KW - Nutrient loading KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41053246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2008%29&rft.atitle=Science+Reassessment+of+Hypoxia+in+the+Gulf+of+Mexico+and+Actions+Needed+to+Reduce+Nutrient+Loads+to+the+Gulf&rft.au=Greene%2C+Rick%3BDavid%2C+Mark%3BMcKenna%2C+Dennis+P&rft.aulast=Greene&rft.aufirst=Rick&rft.date=2008-07-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://spreadsheets.google.com/pub?key=pIk8xgUTyLUGMJGwArtdDGw LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Watershed Central - A Web Site to Find and Use Watershed Information T2 - 2008 Annual Conference of the Soil and Water Conservation Society (SWCS 2008) AN - 41052832; 4910793 JF - 2008 Annual Conference of the Soil and Water Conservation Society (SWCS 2008) AU - Lehman, Stuart Y1 - 2008/07/26/ PY - 2008 DA - 2008 Jul 26 KW - Watersheds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41052832?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2008%29&rft.atitle=Watershed+Central+-+A+Web+Site+to+Find+and+Use+Watershed+Information&rft.au=Lehman%2C+Stuart&rft.aulast=Lehman&rft.aufirst=Stuart&rft.date=2008-07-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Conference+of+the+Soil+and+Water+Conservation+Society+%28SWCS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://spreadsheets.google.com/pub?key=pIk8xgUTyLUGMJGwArtdDGw LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - EPA's Future Midwestern Landscapes (FML) Study T2 - 2008 Annual Conference of the Soil and Water Conservation Society (SWCS 2008) AN - 41052443; 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4910031 JF - 22nd Annual Meeting of the Society for Conservation Biology (SCB 2008) AU - Rashleigh, Brenda AU - Roux, Dirk AU - Ashton, Peter AU - Brajevich, Nikki Y1 - 2008/07/13/ PY - 2008 DA - 2008 Jul 13 KW - USA KW - South Africa KW - Conservation KW - Rivers KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41046557?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=22nd+Annual+Meeting+of+the+Society+for+Conservation+Biology+%28SCB+2008%29&rft.atitle=Comparative+Analysis+of+River+Conservation+in+the+United+States+and+South+Africa&rft.au=Rashleigh%2C+Brenda%3BRoux%2C+Dirk%3BAshton%2C+Peter%3BBrajevich%2C+Nikki&rft.aulast=Rashleigh&rft.aufirst=Brenda&rft.date=2008-07-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=22nd+Annual+Meeting+of+the+Society+for+Conservation+Biology+%28SCB+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.conbio.org/activities/meetings/2008/program/SCB2008_Abstrac t_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Fishing for Novel Approaches to Ecosystem Service Forecasts T2 - 22nd Annual Meeting of the Society for Conservation Biology (SCB 2008) AN - 41043750; 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4902876 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Barron, Mace AU - Vivian, Deborah AU - Yee, Susan AU - Santavy, Debbie Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - USA, Florida KW - Coral reefs KW - Solar radiation KW - Data processing KW - Dosimetry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41045634?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Solar+Radiation+Dosimetry+in+Florida+Coral+Reefs+Determined+from+Remote+Sensed%2C+Modeled%2C+and+In+Situ+Data&rft.au=Barron%2C+Mace%3BVivian%2C+Deborah%3BYee%2C+Susan%3BSantavy%2C+Debbie&rft.aulast=Barron&rft.aufirst=Mace&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Estimating Three-Dimensional Coral Colony Surface Area from Simple Field Measurements T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41044154; 4902877 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Courtney, Lee AU - Fisher, William AU - Raimondo, Sandy AU - Oliver, Leah AU - Davis, William Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - Surface area KW - Coral reefs KW - Colonies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41044154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Estimating+Three-Dimensional+Coral+Colony+Surface+Area+from+Simple+Field+Measurements&rft.au=Courtney%2C+Lee%3BFisher%2C+William%3BRaimondo%2C+Sandy%3BOliver%2C+Leah%3BDavis%2C+William&rft.aulast=Courtney&rft.aufirst=Lee&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Quantifying Environmental Influences on Coral Bleaching in the Florida Keys Using Multi-species Models T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41042445; 4903270 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Yee, Susan AU - Santavy, Deborah AU - Barron, Mace Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - USA, Florida, Florida Keys KW - Coral bleaching KW - Coral reefs KW - Bleaching KW - Models UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41042445?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Quantifying+Environmental+Influences+on+Coral+Bleaching+in+the+Florida+Keys+Using+Multi-species+Models&rft.au=Yee%2C+Susan%3BSantavy%2C+Deborah%3BBarron%2C+Mace&rft.aulast=Yee&rft.aufirst=Susan&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Water Quality Standards for Coral Reef Protection T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41041899; 4903647 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Fisher, William AU - Hutchins, Aaron AU - Fore, Leska AU - Davis, Wayne AU - Lobue, Charles AU - Bell, Heidi Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - Water quality standards KW - Coral reefs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41041899?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Water+Quality+Standards+for+Coral+Reef+Protection&rft.au=Fisher%2C+William%3BHutchins%2C+Aaron%3BFore%2C+Leska%3BDavis%2C+Wayne%3BLobue%2C+Charles%3BBell%2C+Heidi&rft.aulast=Fisher&rft.aufirst=William&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Strategic Approach for Developing a National Baseline Coral Reef Condition T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41037867; 4902994 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Bradley, Patricia AU - Davis, Wayne AU - Fisher, William AU - Mcdonald, Michael Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - Coral reefs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41037867?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=A+Strategic+Approach+for+Developing+a+National+Baseline+Coral+Reef+Condition&rft.au=Bradley%2C+Patricia%3BDavis%2C+Wayne%3BFisher%2C+William%3BMcdonald%2C+Michael&rft.aulast=Bradley&rft.aufirst=Patricia&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Species Specific Responses to Experimental Bleaching of Corals T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41037740; 4903895 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Vivian, Deborah AU - Yee, Susan AU - Kell, Sarah AU - Mcgill, Cheryl AU - Barron, Mace Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - Bleaching KW - Coral reefs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41037740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Species+Specific+Responses+to+Experimental+Bleaching+of+Corals&rft.au=Vivian%2C+Deborah%3BYee%2C+Susan%3BKell%2C+Sarah%3BMcgill%2C+Cheryl%3BBarron%2C+Mace&rft.aulast=Vivian&rft.aufirst=Deborah&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Patterns of Coral Diseases in the Florida Keys from 1998 2005 T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41036329; 4902195 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Santavy, Deborah AU - Yee, Susan AU - Barron, Mace Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - USA, Florida, Florida Keys KW - Coral reefs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41036329?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Patterns+of+Coral+Diseases+in+the+Florida+Keys+from+1998+2005&rft.au=Santavy%2C+Deborah%3BYee%2C+Susan%3BBarron%2C+Mace&rft.aulast=Santavy&rft.aufirst=Deborah&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Improvements in Determination of Mitigation Needs for Coral Reef Damage: The Case of Guam T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41034554; 4903558 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Gawel, Mike Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - Pacific, Northern Mariana Is., Guam KW - Coral reefs KW - Mitigation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41034554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Improvements+in+Determination+of+Mitigation+Needs+for+Coral+Reef+Damage%3A+The+Case+of+Guam&rft.au=Gawel%2C+Mike&rft.aulast=Gawel&rft.aufirst=Mike&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development and Implementation of Coral Reef Biocriteria in U.S. Jurisdictions T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41032780; 4903658 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Bradley, Patricia AU - Davis, Wayne AU - Fisher, William AU - Heidi, Bell AU - Chan, Valerie AU - Lobue, Buddy AU - Wiltse, Wendy Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - USA KW - Coral reefs KW - Jurisdiction UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41032780?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Development+and+Implementation+of+Coral+Reef+Biocriteria+in+U.S.+Jurisdictions&rft.au=Bradley%2C+Patricia%3BDavis%2C+Wayne%3BFisher%2C+William%3BHeidi%2C+Bell%3BChan%2C+Valerie%3BLobue%2C+Buddy%3BWiltse%2C+Wendy&rft.aulast=Bradley&rft.aufirst=Patricia&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Developing a Preliminary Index of Coral Reef Health T2 - 11th International Coral Reef Symposium (ICRS 2008) AN - 41030835; 4903046 JF - 11th International Coral Reef Symposium (ICRS 2008) AU - Helyer, Jason AU - Meng, Lesa AU - Heltshe, James Y1 - 2008/07/07/ PY - 2008 DA - 2008 Jul 07 KW - Coral reefs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41030835?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.atitle=Developing+a+Preliminary+Index+of+Coral+Reef+Health&rft.au=Helyer%2C+Jason%3BMeng%2C+Lesa%3BHeltshe%2C+James&rft.aulast=Helyer&rft.aufirst=Jason&rft.date=2008-07-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=11th+International+Coral+Reef+Symposium+%28ICRS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/ICRS2008/Itinerary/SearchHome.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Assessing vulnerabilities from alternative development patterns AN - 20901611; 8341124 AB - Planners in a rapidly urbanizing area must take into account trade-offs between multiple environmental issues of concern. A 15-county region, centered on Charlotte, North Carolina, is experiencing a boom in growth resulting in both air and water quality concerns. We examine changes to environmental and socio-economic factors across the region for two contrasting alternative future scenarios of land use development. We found that a ''compact centers'' development, with relatively high density, resulted in improved environmental quality in most counties as a result of lower land consumption. The compact centers development was associated with greater non-point source phosphorus and sediment loads in watersheds that contained urban centers. In contrast, the greater land consumption associated with the medium density development consumed high nutrient-generating agricultural lands, resulting in lower non-point source nitrogen loading to waterways. We also found that compact center development made sense economically in urban areas and reduced expenditures in rural areas. However, compact centers carried the risk of lower tax revenues in rural areas if future values of multi-unit houses were valued at current market rates. By incorporating spatial dynamics in our assessment we provided a means to evaluate future environmental and economic patterns under different alternative growth scenarios across multiple counties. In addition, we found that by conducting our analysis at two different scales (e.g., regional and local), decisions on where to target development and resources could be refined. JF - Landscape and Urban Planning AU - Mehaffey, M AU - Wainger, L AU - Wade, T AU - Yankee, D AU - Smith, E AU - Bott, V AU - Yarbourgh, R AD - U.S. EPA National Exposure Research Laboratory, RTP, NC, United States, mehaffey.megan@epa.gov Y1 - 2008/07/03/ PY - 2008 DA - 2008 Jul 03 SP - 84 EP - 95 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 87 IS - 1 SN - 0169-2046, 0169-2046 KW - Ecology Abstracts; Pollution Abstracts; Sustainability Science Abstracts KW - USA, North Carolina KW - water quality KW - Housing KW - Phosphorus KW - Socioeconomics KW - Nutrients KW - Development KW - Watersheds KW - local decisions KW - Urban planning KW - Taxation KW - Agricultural land KW - Risk factors KW - Economics KW - Planning KW - Urban areas KW - Sediment pollution KW - Landscape KW - agricultural land KW - Nonpoint pollution KW - Land use KW - Residential areas KW - Environmental quality KW - vulnerability KW - Rural areas KW - Nitrogen KW - P 2000:FRESHWATER POLLUTION KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20901611?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Landscape+and+Urban+Planning&rft.atitle=Assessing+vulnerabilities+from+alternative+development+patterns&rft.au=Mehaffey%2C+M%3BWainger%2C+L%3BWade%2C+T%3BYankee%2C+D%3BSmith%2C+E%3BBott%2C+V%3BYarbourgh%2C+R&rft.aulast=Mehaffey&rft.aufirst=M&rft.date=2008-07-03&rft.volume=87&rft.issue=1&rft.spage=84&rft.isbn=&rft.btitle=&rft.title=Landscape+and+Urban+Planning&rft.issn=01692046&rft_id=info:doi/10.1016%2Fj.landurbplan.2008.04.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Agricultural land; Risk factors; Planning; Landscape; Economics; Development; Watersheds; Nitrogen; water quality; Sediment pollution; Housing; Phosphorus; Socioeconomics; Nutrients; agricultural land; Nonpoint pollution; local decisions; Land use; Taxation; Urban planning; Residential areas; Environmental quality; vulnerability; Urban areas; Rural areas; USA, North Carolina DO - http://dx.doi.org/10.1016/j.landurbplan.2008.04.010 ER - TY - JOUR T1 - Suppression of the steroid-primed luteinizing hormone surge in the female rat by sodium dimethyldithiocarbamate: relationship to hypothalamic catecholamines and GnRH neuronal activation. AN - 71677408; 18397915 AB - In female rodents, hypothalamic norepinephrine (NE) has a role in stimulating the secretion of gonadotropin-releasing hormone (GnRH) that triggers the ovulatory surge of luteinizing hormone (LH). NE synthesis from dopamine (DA) is catalyzed by dopamine-beta-hydroxylase (DbetaH) which contains a copper cofactor. Sodium dimethyldithiocarbamate (DMDC) is a pesticide with metal chelating properties that has been found to reduce DbetaH activity. The resultant decrease in NE causes a suppression of both the LH surge and ovulation. The present study examined the dose-related impact of DMDC on hypothalamic GnRH neuronal activation indicated by the nuclear presence of the early gene product c-fos. It represents an essential link between effects on NE and suppression of the surge. Ovariectomized (OVX), estradiol-, and progesterone-primed Sprague-Dawley rats were given a single ip injection of 0, 3.6, 7.1, 14.2, or 28.4 mg/kg DMDC in separate groups of females to assess tissue GnRH/c-fos immunostaining, hypothalamic catecholamines, and serial blood samplings for LH. A dose-related decline in hypothalamic NE and increase in DA at 2 h after DMDC administration were consistent with a decrease in c-fos-positive GnRH neurons, with an almost complete absence of c-fos at the two highest doses. The effects correlated well with a suppression of the surge, although the percentage decrease in c-fos neurons at 7.1 mg/kg only attenuated the surge peak, not the overall amount of circulating LH. The present data offer further evidence that the impact of DMDC on the LH surge is central in origin and in doing so defines the toxic pathway for this effect on ovulation. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Goldman, Jerome M AU - Murr, Ashley S AU - Buckalew, Angela R AU - Cooper, Ralph L AD - Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. goldman.jerome@epa.gov Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 107 EP - 112 VL - 104 IS - 1 KW - Dimethyldithiocarbamate KW - 0 KW - Pesticides KW - Proto-Oncogene Proteins c-fos KW - Gonadotropin-Releasing Hormone KW - 33515-09-2 KW - Luteinizing Hormone KW - 9002-67-9 KW - Norepinephrine KW - X4W3ENH1CV KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Proto-Oncogene Proteins c-fos -- metabolism KW - Female KW - Gonadotropin-Releasing Hormone -- metabolism KW - Neurons -- metabolism KW - Dimethyldithiocarbamate -- toxicity KW - Hypothalamus -- drug effects KW - Norepinephrine -- metabolism KW - Neurons -- drug effects KW - Hypothalamus -- metabolism KW - Luteinizing Hormone -- metabolism KW - Pesticides -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71677408?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Suppression+of+the+steroid-primed+luteinizing+hormone+surge+in+the+female+rat+by+sodium+dimethyldithiocarbamate%3A+relationship+to+hypothalamic+catecholamines+and+GnRH+neuronal+activation.&rft.au=Goldman%2C+Jerome+M%3BMurr%2C+Ashley+S%3BBuckalew%2C+Angela+R%3BCooper%2C+Ralph+L&rft.aulast=Goldman&rft.aufirst=Jerome&rft.date=2008-07-01&rft.volume=104&rft.issue=1&rft.spage=107&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=1096-0929&rft_id=info:doi/10.1093%2Ftoxsci%2Fkfn074 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-07 N1 - Date created - 2008-06-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/toxsci/kfn074 ER - TY - JOUR T1 - Effects of a 3beta-hydroxysteroid dehydrogenase inhibitor, trilostane, on the fathead minnow reproductive axis. AN - 71657551; 18397916 AB - A number of environmental contaminants and plant flavonoid compounds have been shown to inhibit the activity of 3beta-hydroxysteroid dehydrogenase/Delta(5)-Delta(4) isomerase (3beta-HSD). Because 3beta-HSD plays a critical role in steroid hormone synthesis, inhibition of 3beta-HSD represents a potentially important mode of endocrine disruption that may cause reproductive dysfunction in fish or other vertebrates. The objective of this study was to test the hypothesis that exposure to the model 3beta-HSD inhibitor, trilostane, would adversely affect reproductive success of the fathead minnow (Pimephales promelas). Results of in vitro experiments with fathead minnow ovary tissue demonstrated that trilostane inhibited 17beta-estradiol (E2) production in a concentration- and time-dependent manner, and that the effect was eliminated by providing a substrate (progesterone) that does not require 3beta-HSD activity for conversion to E2. Exposure of fish to trilostane caused a significant reduction in spawning frequency and reduced cumulative egg production over the course of the 21-day test. In females, exposure to 1500 mug trilostane/l reduced plasma vitellogenin concentrations, but did not cause significant histological alterations. In males, average trilostane concentrations as low as 50 mug/l significantly increased testis mass and gonadal somatic index. Trilostane exposure did not influence the abundance of mRNA transcripts coding for 3beta-HSD or other steroidogenesis-regulating proteins in males or females. As a whole, results of this study support the hypothesis that 3beta-HSD inhibition can cause reproductive dysfunction in fish, but did not yield a clear profile of responses at multiple levels of biological organization that could be used to diagnose this mode of action. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Villeneuve, Daniel L AU - Blake, Lindsey S AU - Brodin, Jeffrey D AU - Cavallin, Jenna E AU - Durhan, Elizabeth J AU - Jensen, Kathleen M AU - Kahl, Michael D AU - Makynen, Elizabeth A AU - Martinovic, Dalma AU - Mueller, Nathaniel D AU - Ankley, Gerald T AD - Mid-Continent Ecology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Office of Research and Development, 6201 Congdon Boulevard, Duluth, Minnesota 55804, USA. villeneuve.dan@epa.gov Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 113 EP - 123 VL - 104 IS - 1 KW - Aromatase Inhibitors KW - 0 KW - Endocrine Disruptors KW - RNA, Messenger KW - Vitellogenins KW - Dihydrotestosterone KW - 08J2K08A3Y KW - Estradiol KW - 4TI98Z838E KW - 17-Hydroxysteroid Dehydrogenases KW - EC 1.1.- KW - 3 (or 17)-beta-hydroxysteroid dehydrogenase KW - EC 1.1.1.51 KW - Aromatase KW - EC 1.14.14.1 KW - trilostane KW - L0FPV48Q5R KW - Index Medicus KW - Animals KW - Vitellogenins -- blood KW - Reproduction -- drug effects KW - Ovary -- drug effects KW - Estradiol -- metabolism KW - Testis -- growth & development KW - Ovary -- metabolism KW - Estradiol -- blood KW - Testis -- drug effects KW - Aromatase -- metabolism KW - RNA, Messenger -- metabolism KW - Aromatase Inhibitors -- metabolism KW - Gene Expression Regulation -- drug effects KW - Female KW - Male KW - Endocrine Disruptors -- toxicity KW - Dihydrotestosterone -- toxicity KW - Cyprinidae -- physiology KW - Dihydrotestosterone -- analogs & derivatives KW - 17-Hydroxysteroid Dehydrogenases -- genetics KW - Cyprinidae -- blood KW - 17-Hydroxysteroid Dehydrogenases -- antagonists & inhibitors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71657551?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Effects+of+a+3beta-hydroxysteroid+dehydrogenase+inhibitor%2C+trilostane%2C+on+the+fathead+minnow+reproductive+axis.&rft.au=Villeneuve%2C+Daniel+L%3BBlake%2C+Lindsey+S%3BBrodin%2C+Jeffrey+D%3BCavallin%2C+Jenna+E%3BDurhan%2C+Elizabeth+J%3BJensen%2C+Kathleen+M%3BKahl%2C+Michael+D%3BMakynen%2C+Elizabeth+A%3BMartinovic%2C+Dalma%3BMueller%2C+Nathaniel+D%3BAnkley%2C+Gerald+T&rft.aulast=Villeneuve&rft.aufirst=Daniel&rft.date=2008-07-01&rft.volume=104&rft.issue=1&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=1096-0929&rft_id=info:doi/10.1093%2Ftoxsci%2Fkfn073 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-07 N1 - Date created - 2008-06-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/toxsci/kfn073 ER - TY - JOUR T1 - An observational study of the potential for human exposures to pet-borne diazinon residues following lawn applications. AN - 71646731; 18448091 AB - This study examined the potential for pet dogs to be an important pathway for transporting diazinon residues into homes and onto its occupants following residential lawn applications. The primary objectives were to investigate the potential exposures of occupants and their pet dogs to diazinon after an application to turf at their residences and to determine if personal contacts between occupants and their pet dogs resulted in measurable exposures. It was conducted from April to August 2001 before the Agency phased out all residential uses of diazinon in December 2004. Six families and their pet dogs were recruited into the study. Monitoring was conducted at pre-, 1, 2, 4, and 8 days post-application of a commercial, granular formulation of diazinon to the lawn by the homeowner. Environmental samples collected included soil, indoor air, carpet dust, and transferable residues from lawns and floors. Samples collected from the pet dogs consisted of paw wipes, fur clippings, and transferable residues from the fur by a technician or child wearing a cotton glove(s). First morning void (FMV) urine samples were collected from each child and his/her parent on each sampling day. Diazinon was analyzed in all samples, except urine, by GC-MS. The metabolite 2-isopropyl-4-methyl-6-hydroxypyrimidine (IMPy) was analyzed in the urine samples by HPLC-MS/MS. Mean airborne residues of diazinon on day 1 post-application were at least six times higher in both the living rooms (235+/-267 ng/m(3)) and children's bedrooms (179+/-246 ng/m(3)) than at pre-application. Mean loadings of diazinon in carpet dust samples were at least 20 times greater on days 2, 4, and 8 post-application than mean loadings (0.03+/-0.04 ng/cm(2)) at pre-application. The pet dogs had over 900 times higher mean loadings of diazinon residues on their paws on day 1 post-application (88.1+/-100.1 ng/cm(2)) compared to mean loadings (0.05) at pre-application compared to post-application of diazinon to turf. The results showed that the participants and their pet dogs were likely exposed to low levels of diazinon residues from several sources (i.e., air, dust, and soil), through several pathways and routes, after lawn applications at these residences. Lastly, the pet dog appears to be an important pathway for the transfer and translocation of diazinon residues inside the homes and likely exposed occupants through personal contacts (i.e., petting). JF - Environmental research AU - Morgan, Marsha K AU - Stout, Daniel M AU - Jones, Paul A AU - Barr, Dana B AD - USEPA, National Exposure Research Laboratory, Research Triangle Park, NC 27709, USA. morgan.marsha@epa.gov Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 336 EP - 342 VL - 107 IS - 3 KW - Pesticide Residues KW - 0 KW - Diazinon KW - YUS1M1Q929 KW - Index Medicus KW - Environmental Monitoring KW - Animals KW - Humans KW - Dogs KW - Child KW - Male KW - Female KW - Animals, Domestic KW - Housing -- standards KW - Pesticide Residues -- urine KW - Environmental Exposure -- analysis KW - Diazinon -- urine KW - Pesticide Residues -- analysis KW - Diazinon -- analysis KW - Gardening -- standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71646731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+research&rft.atitle=An+observational+study+of+the+potential+for+human+exposures+to+pet-borne+diazinon+residues+following+lawn+applications.&rft.au=Morgan%2C+Marsha+K%3BStout%2C+Daniel+M%3BJones%2C+Paul+A%3BBarr%2C+Dana+B&rft.aulast=Morgan&rft.aufirst=Marsha&rft.date=2008-07-01&rft.volume=107&rft.issue=3&rft.spage=336&rft.isbn=&rft.btitle=&rft.title=Environmental+research&rft.issn=1096-0953&rft_id=info:doi/10.1016%2Fj.envres.2008.03.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-27 N1 - Date created - 2008-06-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.envres.2008.03.004 ER - TY - JOUR T1 - Engaging young people in children's environmental health protection through CARE. AN - 69470395; 18724506 JF - Journal of environmental health AU - Coopwood, Ted AD - U.S. EPA Office of Children's Health Protection and Environmental Education, USA. PY - 2008 SP - 64 EP - 65 VL - 71 IS - 1 SN - 0022-0892, 0022-0892 KW - Index Medicus KW - United States KW - United States Environmental Protection Agency KW - Humans KW - Child KW - Adolescent KW - Health Promotion -- organization & administration KW - Environmental Exposure -- prevention & control KW - Community-Institutional Relations KW - Child Welfare UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69470395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+health&rft.atitle=Engaging+young+people+in+children%27s+environmental+health+protection+through+CARE.&rft.au=Coopwood%2C+Ted&rft.aulast=Coopwood&rft.aufirst=Ted&rft.date=2008-07-01&rft.volume=71&rft.issue=1&rft.spage=64&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+health&rft.issn=00220892&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-12-16 N1 - Date created - 2008-08-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Determining the efficacy of liquid sporicides against spores of Bacillus subtilis on a hard nonporous surface using the quantitative three step method: collaborative study. AN - 69465917; 18727544 AB - A collaborative study was conducted to validate the quantitative Three Step Method (TSM), a method designed to measure the performance of liquid sporicides on a hard nonporous surface. Ten laboratories agreed to participate in the collaborative study; data from 8 of 10 participating laboratories were used in the final statistical analysis. The TSM uses 5 x 5 x 1 mm glass coupons (carriers) upon which spores have been inoculated and which are introduced into liquid sporicidal agent contained in a microcentrifuge tube. Following exposure to a test chemical and a neutralization agent, spores are removed from carriers in 3 fractions: passive removal (Fraction A), sonication (Fraction B), and gentle agitation (Fraction C). Liquid from each fraction is serially diluted and plated on a recovery medium for spore enumeration. Control counts are compared to the treated counts, and the level of efficacy is determined by calculating the log10 reduction (LR) of spores. The main statistical goals were to evaluate the repeatability and reproducibility of the LR values, to estimate the components of variance for LR, and to assess method responsiveness. AOAC Method 966.04-Method II was used as a reference method. The scope of the validation was limited to testing liquid formulations against spores of Bacillus subtilis, a surrogate for virulent strains of B. anthracis, on a hard nonporous surface (glass). The test chemicals used in the study were sodium hypochlorite, a combination of peracetic acid and hydrogen peroxide, and glutaraldehyde. Each test chemical was evaluated at 3 levels of presumed efficacy: high, medium, and low. Three replications were required. The TSM was validated as it successfully met the statistical parameters for quantitative test methods. Satisfactory validation parameters, such as the repeatability standard deviation (Sr) and reproducibility standard deviation (SR), were obtained for control carrier counts and LR values. Both the TSM and the reference method were responsive to the efficacy levels of the test chemicals. For the 72 total TSM tests conducted, the mean (+/- standard error of the mean) log density of spores per control carrier was 6.86 (+/- 0.08); the Sr and SR were low at 0.15 and 0.27, respectively. Across the range of test chemicals, the Sr and SR estimates associated with LR were also acceptably low. The Sr ranged from 0.17 to 0.72 and the SR ranged from 0.34 to 1.43. Overall, the Sr and SR estimates associated with the efficacy data were within the ranges published for other quantitative methods and meet the performance characteristics necessary for validation. JF - Journal of AOAC International AU - Tomasino, Stephen F AU - Pines, Rebecca M AU - Cottrill, Michele P AU - Hamilton, Martin A AD - U.S. Environmental Protection Agency, Office of Pesticide Programs, Microbiology Laboratory Branch, Environmental Science Center, Ft. Meade, MD 20755-5350, USA. tomasino.stephen@epamail.epa.gov PY - 2008 SP - 833 EP - 852 VL - 91 IS - 4 SN - 1060-3271, 1060-3271 KW - Anti-Bacterial Agents KW - 0 KW - Culture Media KW - Disinfectants KW - Indicators and Reagents KW - Oxidants KW - Sodium Hypochlorite KW - DY38VHM5OD KW - Peracetic Acid KW - I6KPI2E1HD KW - Hydrochloric Acid KW - QTT17582CB KW - Glutaral KW - T3C89M417N KW - Index Medicus KW - Bacillus anthracis -- drug effects KW - Analysis of Variance KW - Reproducibility of Results KW - Glutaral -- pharmacology KW - Oxidants -- pharmacology KW - Reference Standards KW - Hydrochloric Acid -- pharmacology KW - Biological Assay KW - Calibration KW - Water Microbiology KW - Disinfectants -- pharmacology KW - Sodium Hypochlorite -- pharmacology KW - Peracetic Acid -- pharmacology KW - Quality Control KW - Surface Properties KW - Spores, Bacterial -- drug effects KW - Anti-Bacterial Agents -- pharmacology KW - Bacillus subtilis -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69465917?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+AOAC+International&rft.atitle=Determining+the+efficacy+of+liquid+sporicides+against+spores+of+Bacillus+subtilis+on+a+hard+nonporous+surface+using+the+quantitative+three+step+method%3A+collaborative+study.&rft.au=Tomasino%2C+Stephen+F%3BPines%2C+Rebecca+M%3BCottrill%2C+Michele+P%3BHamilton%2C+Martin+A&rft.aulast=Tomasino&rft.aufirst=Stephen&rft.date=2008-07-01&rft.volume=91&rft.issue=4&rft.spage=833&rft.isbn=&rft.btitle=&rft.title=Journal+of+AOAC+International&rft.issn=10603271&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-25 N1 - Date created - 2008-08-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Nowcasting and forecasting concentrations of biological contaminants at beaches: a feasibility and case study. AN - 69387386; 18678011 AB - Public concern over microbial contamination of recreational waters has increased in recent years. A common approach to evaluating beach water quality has been to use the persistence model which assumes that day-old monitoring results provide accurate estimates of current concentrations. This model is frequently incorrect Recent studies have shown that statistical regression models based on least-squares fitting often are more accurate. To make such models more generally available, the Virtual Beach (VB) tool was developed. VB is public-domain software that prescribes site-specific predictive models. In this study we used VB as a tool to evaluate statistical modeling for predicting Escherichia coli (E. coli levels at Huntington Beach, on Lake Erie. The models were based on readily available weather and environmental data, plus U.S. Geological Service onsite data. Although models for Great Lakes beaches have frequently been fitted to multiyear data sets, this work demonstrates that useful statistical models can be based on limited data sets collected over much shorter time periods, leading to dynamic models that are periodically refitted as new data become available. Comparisons of the resulting nowcasts (predictions of current, but yet unknown, bacterial levels) with observations verified the effectiveness of VB and showed that dynamic models are about as accurate as long-term static models. Finally, fitting models to forecasted explanatory variables, bacteria forecasts were found to compare favorably to nowcasts, yielding adjusted coefficients of determination (adjusted R2) of about 0.40. JF - Environmental science & technology AU - Frick, Walter E AU - Ge, Zhongfu AU - Zepp, Richard G AD - Ecosystems Research Division, U.S. Environmental Protection Agency, Athens, Georgia 30605, USA. frick.walter@epa.gov Y1 - 2008/07/01/ PY - 2008 DA - 2008 Jul 01 SP - 4818 EP - 4824 VL - 42 IS - 13 SN - 0013-936X, 0013-936X KW - Index Medicus KW - Regression Analysis KW - Feasibility Studies KW - Escherichia coli -- isolation & purification KW - Least-Squares Analysis KW - Ohio KW - Software KW - Forecasting -- methods KW - Fresh Water -- microbiology KW - Water Microbiology KW - Models, Biological KW - Environmental Monitoring -- methods KW - Bathing Beaches -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69387386?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Nowcasting+and+forecasting+concentrations+of+biological+contaminants+at+beaches%3A+a+feasibility+and+case+study.&rft.au=Frick%2C+Walter+E%3BGe%2C+Zhongfu%3BZepp%2C+Richard+G&rft.aulast=Frick&rft.aufirst=Walter&rft.date=2008-07-01&rft.volume=42&rft.issue=13&rft.spage=4818&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-09 N1 - Date created - 2008-08-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Traffic and meteorological impacts on near-road air quality: summary of methods and trends from the Raleigh Near-Road Study. AN - 69375670; 18672711 AB - A growing number of epidemiological studies conducted worldwide suggest an increase in the occurrence of adverse health effects in populations living, working, or going to school near major roadways. A study was designed to assess traffic emissions impacts on air quality and particle toxicity near a heavily traveled highway. In an attempt to describe the complex mixture of pollutants and atmospheric transport mechanisms affecting pollutant dispersion in this near-highway environment, several real-time and time-integrated sampling devices measured air quality concentrations at multiple distances and heights from the road. Pollutants analyzed included U.S. Environmental Protection Agency (EPA)-regulated gases, particulate matter (coarse, fine, and ultrafine), and air toxics. Pollutant measurements were synchronized with real-time traffic and meteorological monitoring devices to provide continuous and integrated assessments of the variation of near-road air pollutant concentrations and particle toxicity with changing traffic and environmental conditions, as well as distance from the road. Measurement results demonstrated the temporal and spatial impact of traffic emissions on near-road air quality. The distribution of mobile source emitted gas and particulate pollutants under all wind and traffic conditions indicated a higher proportion of elevated concentrations near the road, suggesting elevated exposures for populations spending significant amounts of time in this microenvironment. Diurnal variations in pollutant concentrations also demonstrated the impact of traffic activity and meteorology on near-road air quality. Time-resolved measurements of multiple pollutants demonstrated that traffic emissions produced a complex mixture of criteria and air toxic pollutants in this microenvironment. These results provide a foundation for future assessments of these data to identify the relationship of traffic activity and meteorology on air quality concentrations and population exposures. JF - Journal of the Air & Waste Management Association (1995) AU - Baldauf, Richard AU - Thoma, Eben AU - Hays, Michael AU - Shores, Richard AU - Kinsey, John AU - Gullett, Brian AU - Kimbrough, Sue AU - Isakov, Vlad AU - Long, Thomas AU - Snow, Richard AU - Khlystov, Andrey AU - Weinstein, Jason AU - Chen, Fu-Lin AU - Seila, Robert AU - Olson, David AU - Gilmour, Ian AU - Cho, Seung-Hyun AU - Watkins, Nealson AU - Rowley, Patricia AU - Bang, John AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, NC 27711, USA. baldauf.richard@epa.gov Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 865 EP - 878 VL - 58 IS - 7 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Vehicle Emissions KW - Carbon Monoxide KW - 7U1EE4V452 KW - Index Medicus KW - North Carolina KW - Air Pollutants -- analysis KW - Time Factors KW - Air Movements KW - Motor Vehicles KW - Weather UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69375670?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Traffic+and+meteorological+impacts+on+near-road+air+quality%3A+summary+of+methods+and+trends+from+the+Raleigh+Near-Road+Study.&rft.au=Baldauf%2C+Richard%3BThoma%2C+Eben%3BHays%2C+Michael%3BShores%2C+Richard%3BKinsey%2C+John%3BGullett%2C+Brian%3BKimbrough%2C+Sue%3BIsakov%2C+Vlad%3BLong%2C+Thomas%3BSnow%2C+Richard%3BKhlystov%2C+Andrey%3BWeinstein%2C+Jason%3BChen%2C+Fu-Lin%3BSeila%2C+Robert%3BOlson%2C+David%3BGilmour%2C+Ian%3BCho%2C+Seung-Hyun%3BWatkins%2C+Nealson%3BRowley%2C+Patricia%3BBang%2C+John&rft.aulast=Baldauf&rft.aufirst=Richard&rft.date=2008-07-01&rft.volume=58&rft.issue=7&rft.spage=865&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-28 N1 - Date created - 2008-08-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Characterization of near-road pollutant gradients using path-integrated optical remote sensing. AN - 69375299; 18672712 AB - Understanding motor vehicle emissions, near-roadway pollutant dispersion, and their potential impact to near-roadway populations is an area of growing environmental interest. As part of ongoing U.S. Environmental Protection Agency research in this area, a field study was conducted near Interstate 440 (I-440) in Raleigh, NC, in July and August of 2006. This paper presents a subset of measurements from the study focusing on nitric oxide (NO) concentrations near the roadway. Measurements of NO in this study were facilitated by the use of a novel path-integrated optical remote sensing technique called deep ultraviolet differential optical absorption spectroscopy (DUV-DOAS). This paper reviews the development and application of this measurement system. Time-resolved near-road NO concentrations are analyzed in conjunction with wind and traffic data to provide a picture of emissions and near-road dispersion for the study. Results show peak NO concentrations in the 150 ppb range during weekday morning rush hours with winds from the road accompanied by significantly lower afternoon and weekend concentrations. Traffic volume and wind direction are shown to be primary determinants of NO concentrations with turbulent diffusion and meandering accounting for significant near-road concentrations in off-wind conditions. The enhanced source capture performance of the open-path configuration allowed for robust comparisons of measured concentrations with a composite variable of traffic intensity coupled with wind transport (R2 = 0.84) as well as investigations on the influence of wind direction on NO dilution near the roadway. The benefits of path-integrated measurements for assessing line source impacts and evaluating models is presented. The advantages of NO as a tracer compound, compared with nitrogen dioxide, for investigations of mobile source emissions and initial dispersion under crosswind conditions are also discussed. JF - Journal of the Air & Waste Management Association (1995) AU - Thoma, Eben D AU - Shores, Richard C AU - Isakov, Vlad AU - Baldauf, Richard W AD - Office of Research and Development, National Risk Management Research Laboratory, Air Pollution Prevention and Control Division, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. thoma.eben@epa.gov Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 879 EP - 890 VL - 58 IS - 7 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Vehicle Emissions KW - Nitric Oxide KW - 31C4KY9ESH KW - Index Medicus KW - Transportation KW - Circadian Rhythm KW - Time Factors KW - Wind KW - Motor Vehicles KW - Conservation of Natural Resources KW - Nitric Oxide -- chemistry KW - Air Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69375299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Characterization+of+near-road+pollutant+gradients+using+path-integrated+optical+remote+sensing.&rft.au=Thoma%2C+Eben+D%3BShores%2C+Richard+C%3BIsakov%2C+Vlad%3BBaldauf%2C+Richard+W&rft.aulast=Thoma&rft.aufirst=Eben&rft.date=2008-07-01&rft.volume=58&rft.issue=7&rft.spage=879&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-28 N1 - Date created - 2008-08-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Determining normal variability in a developmental neurotoxicity test: a report from the ILSI Research Foundation/Risk Science Institute expert working group on neurodevelopmental endpoints. AN - 69298121; 18280700 AB - With the implementation of the Food Quality Protection Act in 1996, more detailed evaluations of possible health effects of pesticides on developing organisms have been required. As a result, considerable developmental neurotoxicity (DNT) data have been generated on a variety of endpoints, including developmental changes in motor activity, auditory startle habituation, and various learning and memory parameters. One issue in interpreting these data is the level of variability for the measures used in these studies: excessive variability can obscure treatment-related effects, or conversely, small but statistically significant changes could be viewed as treatment related, when they might in fact be within the normal range. To aid laboratories in designing useful DNT studies for regulatory consideration, an operational framework for evaluating observed variability in study data has been developed. Elements of the framework suggest how an investigator might approach characterization of variability in the dataset; identification of appropriate datasets for comparison; evaluation of similarities and differences in variability between these datasets, and of possible sources of the variability, including those related to test conduct and test design. A case study using auditory startle habituation data is then presented, employing the elements of this proposed approach. JF - Neurotoxicology and teratology AU - Raffaele, Kathleen C AU - Fisher, J Edward AU - Hancock, Scott AU - Hazelden, Keith AU - Sobrian, Sonya K AD - Office of Pesticide Programs, U.S. EPA, Washington, DC, USA. raffaele.kathleen@epa.gov PY - 2008 SP - 288 EP - 325 VL - 30 IS - 4 SN - 0892-0362, 0892-0362 KW - Index Medicus KW - Animals KW - Humans KW - Reference Standards KW - Toxicity Tests -- methods KW - Reflex, Startle -- physiology KW - Data Collection KW - Acoustic Stimulation KW - Toxicity Tests -- standards KW - Models, Animal KW - Research Design -- standards KW - Nervous System Diseases -- physiopathology KW - Nervous System Diseases -- embryology KW - Nervous System Diseases -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69298121?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+teratology&rft.atitle=Determining+normal+variability+in+a+developmental+neurotoxicity+test%3A+a+report+from+the+ILSI+Research+Foundation%2FRisk+Science+Institute+expert+working+group+on+neurodevelopmental+endpoints.&rft.au=Raffaele%2C+Kathleen+C%3BFisher%2C+J+Edward%3BHancock%2C+Scott%3BHazelden%2C+Keith%3BSobrian%2C+Sonya+K&rft.aulast=Raffaele&rft.aufirst=Kathleen&rft.date=2008-07-01&rft.volume=30&rft.issue=4&rft.spage=288&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2007.12.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-11-05 N1 - Date created - 2008-07-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.ntt.2007.12.009 ER - TY - JOUR T1 - Undertaking positive control studies as part of developmental neurotoxicity testing: a report from the ILSI Research Foundation/Risk Science Institute expert working group on neurodevelopmental endpoints. AN - 69296536; 17681747 AB - Developmental neurotoxicity testing involves functional and neurohistological assessments in offspring during and following maternal and/or neonatal exposure. Data from positive control studies are an integral component in developmental neurotoxicity risk assessments. Positive control data are crucial for evaluating a laboratory's capability to detect chemical-induced changes in measured endpoints. Positive control data are also valuable in a weight-of-evidence approach to help determine the biological significance of results and provide confidence in negative results from developmental neurotoxicity (DNT) studies. This review is a practical guide for the selection and use of positive control agents in developmental neurotoxicology. The advantages and disadvantages of various positive control agents are discussed for the endpoints in developmental neurotoxicity studies. Design issues specific to positive control studies in developmental neurotoxicity are considered and recommendations on how to interpret and report positive control data are made. Positive control studies should be conducted as an integral component of the incorporation and use of developmental neurotoxicity testing methods in laboratories that generate data used in risk decisions. JF - Neurotoxicology and teratology AU - Crofton, Kevin M AU - Foss, John A AU - Hass, Ulla AU - Jensen, Karl F AU - Levin, Edward D AU - Parker, Sherry P AD - Neurotoxicology Division, NHEERL, ORD, US EPA, Research Triangle Park, NC, USA. crofton.kevin@epa.gov PY - 2008 SP - 266 EP - 287 VL - 30 IS - 4 SN - 0892-0362, 0892-0362 KW - Index Medicus KW - Sensitivity and Specificity KW - Animals KW - Endpoint Determination KW - Humans KW - Research Design KW - Female KW - Prenatal Exposure Delayed Effects KW - Pregnancy KW - Biomedical Research -- standards KW - Biomedical Research -- methods KW - Neurotoxicity Syndromes -- etiology KW - Neurotoxicity Syndromes -- physiopathology KW - Risk Assessment -- standards KW - Risk Assessment -- methods KW - Quality Control KW - Neurotoxicity Syndromes -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69296536?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+teratology&rft.atitle=Undertaking+positive+control+studies+as+part+of+developmental+neurotoxicity+testing%3A+a+report+from+the+ILSI+Research+Foundation%2FRisk+Science+Institute+expert+working+group+on+neurodevelopmental+endpoints.&rft.au=Crofton%2C+Kevin+M%3BFoss%2C+John+A%3BHass%2C+Ulla%3BJensen%2C+Karl+F%3BLevin%2C+Edward+D%3BParker%2C+Sherry+P&rft.aulast=Crofton&rft.aufirst=Kevin&rft.date=2008-07-01&rft.volume=30&rft.issue=4&rft.spage=266&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+teratology&rft.issn=08920362&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-11-05 N1 - Date created - 2008-07-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Ecological risk assessment in the United States environmental protection agency: a historical overview. AN - 69286007; 18321143 AB - This is 1 of 4 papers from the US Environmental Protection Agency Science Advisory Board's Ecological Processes and Effects Committee workshop on the current and future practice of ecological risk assessment. The workshop was held in Washington, DC in February 2006. Risk assessment originated with the insurance industry and spread to the estimation of risks to people and property in other contexts, including the regulation of environmental contamination. Ecological assessment became an important component of environmental management in the United States with the legal mandate for environmental impact assessment in 1970. Risk assessment and ecological assessment merged in the 1980s to form ecological risk assessment (ERA). Since then, ERA has been institutionalized with the development of the US Environmental Protection Agency's (hereafter, USEPA or Agency) framework and guidance documents. Ecological risk assessment has been adapted by the Agency's program offices to fit their legal and policy contexts. The future of ERA will inevitably include the incorporation of more complex and demanding methods. However, the biggest challenge for future risk assessors will be to make ecological risks more compelling to decision makers. JF - Integrated environmental assessment and management AU - Suter, Glenn W AD - Office of Research and Development, US Environmental Protection Agency, Cincinnati, OH 45268, USA. suter.glenn@epa.gov Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 285 EP - 289 VL - 4 IS - 3 SN - 1551-3777, 1551-3777 KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - United States KW - History, 21st Century KW - History, 20th Century KW - Humans KW - Environmental Health -- history KW - Environmental Health -- standards KW - Guidelines as Topic KW - Environmental Health -- methods KW - United States Environmental Protection Agency -- history KW - Environmental Pollutants -- toxicity KW - United States Environmental Protection Agency -- standards KW - Ecology -- history KW - Risk Assessment -- history KW - Environmental Pollutants -- history KW - Ecology -- methods KW - Risk Assessment -- standards KW - Risk Assessment -- methods KW - Ecology -- standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69286007?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Integrated+environmental+assessment+and+management&rft.atitle=Ecological+risk+assessment+in+the+United+States+environmental+protection+agency%3A+a+historical+overview.&rft.au=Suter%2C+Glenn+W&rft.aulast=Suter&rft.aufirst=Glenn&rft.date=2008-07-01&rft.volume=4&rft.issue=3&rft.spage=285&rft.isbn=&rft.btitle=&rft.title=Integrated+environmental+assessment+and+management&rft.issn=15513777&rft_id=info:doi/10.1897%2FIEAM_2007-062 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-11-04 N1 - Date created - 2008-07-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1897/IEAM_2007-062 ER - TY - JOUR T1 - Analysis of ecologically relevant pharmaceuticals in wastewater and surface water using selective solid-phase extraction and UPLC-MS/MS. AN - 69271985; 18498179 AB - A rapid and sensitive method has been developed for the analysis of 48 human prescription active pharmaceutical ingredients (APIs) and 6 metabolites of interest, utilizing selective solid-phase extraction (SPE) and ultraperformance liquid chromatography in combination with triple quadrupole mass spectrometry (UPLC-MS/MS). The single-cartridge extraction step was developed using a mixed mode reversed-phase/cation-exchange cartridge (Oasis MCX) and validated in both wastewater effluent and surface water. Recoveries for the majority of compounds ranged from 80% to 125%, with relative standard deviations generally below 15%. Analytes were quantified using a multiple injection analysis with four chromatographic runs, with a combined run time of 48 min and SPE-UPLC-MS/MS method detection limits ranging from 1.0 to 51 ng/L. The analysis of seven wastewater effluents and one surface water sample revealed at least one detection for 38 of the 54 compounds, with effluent concentrations ranging from 7 to 2950 ng/L and surface water concentrations ranging from 10 to 140 ng/L. This initial data demonstrates that a significant number of the selected target analytes are present in wastewater treatment plant discharges. JF - Analytical chemistry AU - Batt, Angela L AU - Kostich, Mitch S AU - Lazorchak, James M AD - U.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratories, 26 West Martin Luther King Drive, MS 642, Cincinnati, Ohio 45268, USA. batt.angela@epa.gov Y1 - 2008/07/01/ PY - 2008 DA - 2008 Jul 01 SP - 5021 EP - 5030 VL - 80 IS - 13 KW - Pharmaceutical Preparations KW - 0 KW - Water Pollutants, Chemical KW - Water KW - 059QF0KO0R KW - Index Medicus KW - Reproducibility of Results KW - Water -- analysis KW - Chromatography, Liquid -- methods KW - Water Pollutants, Chemical -- analysis KW - Tandem Mass Spectrometry -- methods KW - Pharmaceutical Preparations -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69271985?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Analysis+of+ecologically+relevant+pharmaceuticals+in+wastewater+and+surface+water+using+selective+solid-phase+extraction+and+UPLC-MS%2FMS.&rft.au=Batt%2C+Angela+L%3BKostich%2C+Mitch+S%3BLazorchak%2C+James+M&rft.aulast=Batt&rft.aufirst=Angela&rft.date=2008-07-01&rft.volume=80&rft.issue=13&rft.spage=5021&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=1520-6882&rft_id=info:doi/10.1021%2Fac800066n LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-12 N1 - Date created - 2008-06-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1021/ac800066n ER - TY - JOUR T1 - Comparing urban air quality in Europe in real time a review of existing air quality indices and the proposal of a common alternative. AN - 69206688; 18234340 AB - The EU directives on air quality force member states to inform the public on the status of the ambient air quality. The Internet is commonly used for this purpose and often air quality is being presented as an index ranging from good to bad. A review of existing websites and air quality indices shows that the way air quality is interpreted differs considerably. The paper presents a new air quality index. The index is part of a project to develop a website dedicated to comparing air quality in European cities. The common air quality index (CAQI) is not aimed at replacing existing local indices. The CAQI is a set of two indices: one for roadside monitoring sites and one for average city background conditions. Differentiating between roadside and general city conditions is a first step in assuring consistence in the parameters that are being compared. JF - Environment international AU - van den Elshout, Sef AU - Léger, Karine AU - Nussio, Fabio AD - DCMR EPA Rijnmond, PO Box 843, 3100 AV Schiedam, The Netherlands. sef.vandenelshout@dcmr.nl Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 720 EP - 726 VL - 34 IS - 5 SN - 0160-4120, 0160-4120 KW - Air Pollutants KW - 0 KW - Index Medicus KW - Europe KW - Internet KW - Air Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69206688?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environment+international&rft.atitle=Comparing+urban+air+quality+in+Europe+in+real+time+a+review+of+existing+air+quality+indices+and+the+proposal+of+a+common+alternative.&rft.au=van+den+Elshout%2C+Sef%3BL%C3%A9ger%2C+Karine%3BNussio%2C+Fabio&rft.aulast=van+den+Elshout&rft.aufirst=Sef&rft.date=2008-07-01&rft.volume=34&rft.issue=5&rft.spage=720&rft.isbn=&rft.btitle=&rft.title=Environment+international&rft.issn=01604120&rft_id=info:doi/10.1016%2Fj.envint.2007.12.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-11-04 N1 - Date created - 2008-06-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.envint.2007.12.011 ER - TY - JOUR T1 - New Regulations to Improve Wetland and Stream Compensatory Mitigation AN - 58836674; 2008-193530 AB - On March 31, 2008, EPA & the Corps issued revised regulations governing compensatory mitigation for authorized impacts on wetlands, streams, & other waters of the United States under Section 404 of the Clean Water Act. Highlights of the new rule are examined below. References. Adapted from the source document. JF - National Wetlands Newsletter AU - Hough, Palmer AU - Sudol, Mark AD - U.S. Environmental Protection Agency Wetlands Division Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 1 EP - 21 PB - Environmental Law Institute, Washington DC VL - 30 IS - 4 SN - 0164-0712, 0164-0712 KW - Environment and environmental policy - Geography and cartography KW - Economic conditions and policy - Economic policy, planning, and development KW - Law and ethics - Law and jurisprudence KW - United States Environmental protection agency KW - Standards KW - Wetlands KW - Regulation KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58836674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=National+Wetlands+Newsletter&rft.atitle=New+Regulations+to+Improve+Wetland+and+Stream+Compensatory+Mitigation&rft.au=Hough%2C+Palmer%3BSudol%2C+Mark&rft.aulast=Hough&rft.aufirst=Palmer&rft.date=2008-07-01&rft.volume=30&rft.issue=4&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=National+Wetlands+Newsletter&rft.issn=01640712&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2009-10-02 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States Environmental protection agency; Wetlands; Regulation; Standards ER - TY - JOUR T1 - A roughness-corrected index of relative bed stability for regional stream surveys AN - 50431455; 2009-049323 AB - Quantitative regional assessments of streambed sedimentation and its likely causes are hampered because field investigations typically lack the requisite sample size, measurements, or precision for sound geomorphic and statistical interpretation. We adapted an index of relative bed stability (RBS) for data calculated from a national stream survey field protocol to enable general evaluation of bed stability and anthropogenic sedimentation in synoptic ecological surveys. RBS is the ratio of bed surface geometric mean particle diameter (D (sub gm) ) divided by estimated critical diameter (D (sub cbf) ) at bankfull flow, based on a modified Shield's criterion for incipient motion. Application of RBS to adequately depict bed stability in complex natural streams, however, has been limited because typical calculations of RBS do not explicitly account for reductions in bed shear stress that result from channel form roughness. We modified the index (RBS*) to incorporate the reduction in bed shear stress available for sediment transport that results from the hydraulic resistance of large wood and longitudinal irregularities in channel dimensions ("form roughness"). Based on dimensional analysis, we derived an adjustment to bankfull shear stress by multiplying the bankfull hydraulic radius (R (sub bf) ) by the one-third power of the ratio of particle-derived resistance to total hydraulic resistance (C (sub p) /C (sub t) ) (super 1/3) , where both resistances are empirically based calculations. We computed C (sub p) using a Keulegan equation relating resistance to relative submergence of bed particles. We then derived an empirical equation to predict reach-scale hydraulic resistance C (sub t) from thalweg mean depth, thalweg mean residual depth, and large wood volume based on field dye transit studies, in which total hydraulic resistance C (sub t) was measured over a wide range of natural stream channel complexity, including manipulation of large wood volumes. We tested our estimates of C (sub t) and RBS* by applying them to data from a summer low flow probability sample of 104 wadeable stream reaches in the Coastal Ecoregion of Oregon and Washington, USA. Stream discharges calculated using these C (sub t) estimates compared favorably with velocity-area measurements of discharge during summer low flow, and with the range of 1 to 2-year recurrence floods (scaled by drainage area) at U.S.Geological Survey gauged sites in the same region. Log [RBS*] ranged from -4.2 to +0.98 in the survey region. D (sub gm) ranged from silt to boulders, while estimated bankfull critical diameter, D* (sub cbf) , ranged from very fine gravel to large boulders. The median value of D* (sub cbf) (adjusted for form roughness influences) averaged 40% (inter quartile range 28 to 59%) of the unadjusted estimate D (sub cbf) . Log[RBS*] was consistently negatively related to human disturbances likely to produce excess sediment inputs or hydrologic alteration. Log [RBS*] ranged from -1.9 to +0.5 in the streams within the lower quartile of human disturbance in their basin and riparian areas and was substantially lower (-4.2 to -1.1) in streams within the upper quartile of human disturbance. The synoptic survey methods and designs we used appear adequate to evaluate regional patterns in bed stability and sedimentation and their general relationship to human disturbances. Although the RBS concept also shows promise for evaluating sediment and bed stability in individual streams, our approach is relatively coarse, so site-specific assessments using these rapid field methods might prudently be confined to identifying severe cases of sedimentation or channel alteration. Greater confidence to discern subtle differences in site-specific assessments could be gained by calculating RBS* using more precise field measurements of channel slope, bed particle size and bankfull dimensions, and by refining our adjustments for energy loss from channel form roughness. JF - Geomorphology AU - Kaufmann, Philip R AU - Faustini, J M AU - Larsen, D P AU - Shirazi, M A Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 150 EP - 170 PB - Elsevier, Amsterdam VL - 99 IS - 1-4 SN - 0169-555X, 0169-555X KW - United States KW - wood KW - shear stress KW - environmental management KW - Oregon KW - river banks KW - quantitative analysis KW - sediments KW - Washington KW - sediment transport KW - clastic sediments KW - human activity KW - grain size KW - statistical analysis KW - sedimentation KW - roughness KW - channels KW - Keulegan equation KW - equations KW - fluvial sedimentation KW - bedforms KW - models KW - mathematical methods KW - fluvial features KW - streams KW - corrections KW - 23:Geomorphology KW - 06A:Sedimentary petrology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50431455?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geomorphology&rft.atitle=A+roughness-corrected+index+of+relative+bed+stability+for+regional+stream+surveys&rft.au=Kaufmann%2C+Philip+R%3BFaustini%2C+J+M%3BLarsen%2C+D+P%3BShirazi%2C+M+A&rft.aulast=Kaufmann&rft.aufirst=Philip&rft.date=2008-07-01&rft.volume=99&rft.issue=1-4&rft.spage=150&rft.isbn=&rft.btitle=&rft.title=Geomorphology&rft.issn=0169555X&rft_id=info:doi/10.1016%2Fj.geomorph.2007.10.007 L2 - http://www.sciencedirect.com/science/journal/0169555X LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2009-01-01 N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - bedforms; channels; clastic sediments; corrections; environmental management; equations; fluvial features; fluvial sedimentation; grain size; human activity; Keulegan equation; mathematical methods; models; Oregon; quantitative analysis; river banks; roughness; sediment transport; sedimentation; sediments; shear stress; statistical analysis; streams; United States; Washington; wood DO - http://dx.doi.org/10.1016/j.geomorph.2007.10.007 ER - TY - JOUR T1 - Medical geology; dust exposure and potential health risks in the Middle East AN - 50391345; 2009-061652 JF - Geochimica et Cosmochimica Acta AU - Lyles, Mark B AU - Frederickson, H L AU - Bednar, A J AU - Fannin, H B AU - Griffin, D AU - Sobecki, T M AU - Anonymous Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 1 PB - Elsevier, New York, NY VL - 72 IS - 12S SN - 0016-7037, 0016-7037 KW - dust storms KW - experimental studies KW - geologic hazards KW - medical geology KW - physicochemical properties KW - grain size KW - pathogens KW - Iraq KW - human ecology KW - Arabian Peninsula KW - military geology KW - fungi KW - metals KW - bacteria KW - viruses KW - risk assessment KW - particulate materials KW - Kuwait KW - Asia KW - Middle East KW - public health KW - microorganisms KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50391345?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geochimica+et+Cosmochimica+Acta&rft.atitle=Medical+geology%3B+dust+exposure+and+potential+health+risks+in+the+Middle+East&rft.au=Lyles%2C+Mark+B%3BFrederickson%2C+H+L%3BBednar%2C+A+J%3BFannin%2C+H+B%3BGriffin%2C+D%3BSobecki%2C+T+M%3BAnonymous&rft.aulast=Lyles&rft.aufirst=Mark&rft.date=2008-07-01&rft.volume=72&rft.issue=12S&rft.spage=A576&rft.isbn=&rft.btitle=&rft.title=Geochimica+et+Cosmochimica+Acta&rft.issn=00167037&rft_id=info:doi/ L2 - http://www.sciencedirect.com/science/journal/00167037 LA - English DB - GeoRef N1 - Conference title - 18th annual V. M. Goldschmidt conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - PubXState - NY N1 - Last updated - 2012-06-07 N1 - CODEN - GCACAK N1 - SubjectsTermNotLitGenreText - Arabian Peninsula; Asia; bacteria; dust storms; experimental studies; fungi; geologic hazards; grain size; human ecology; Iraq; Kuwait; medical geology; metals; microorganisms; Middle East; military geology; particulate materials; pathogens; physicochemical properties; public health; risk assessment; viruses ER - TY - JOUR T1 - Black carbon and sorption of PAHs in natural fire-impacted sediments from Oriole Lake (CA) AN - 50390366; 2009-061634 JF - Geochimica et Cosmochimica Acta AU - Lohmann, Rainer AU - Bollinger, Kevyn AU - King, John AU - Cantwell, Mark AU - Caprio, Tony AU - Anonymous Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 1 PB - Elsevier, New York, NY VL - 72 IS - 12S SN - 0016-7037, 0016-7037 KW - United States KW - Tulare County California KW - Spermatophyta KW - sorption KW - Sequoia National Park KW - isotopes KW - national parks KW - lead KW - Coniferales KW - Holocene KW - air pollution KW - fires KW - Cenozoic KW - California KW - radioactive isotopes KW - chronology KW - cesium KW - black carbon KW - dates KW - carbon KW - sediments KW - absolute age KW - Taxodiaceae KW - hydrology KW - Plantae KW - Quaternary KW - Gymnospermae KW - alkali metals KW - pollution KW - Kings Canyon National Park KW - public lands KW - organic compounds KW - limnology KW - Oriole Lake KW - Cs-137 KW - metals KW - Sequoia KW - lacustrine environment KW - hydrocarbons KW - trees KW - polycyclic aromatic hydrocarbons KW - C-14 KW - upper Holocene KW - aromatic hydrocarbons KW - Pb-210 KW - lake sediments KW - 02D:Isotope geochemistry KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50390366?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geochimica+et+Cosmochimica+Acta&rft.atitle=Black+carbon+and+sorption+of+PAHs+in+natural+fire-impacted+sediments+from+Oriole+Lake+%28CA%29&rft.au=Lohmann%2C+Rainer%3BBollinger%2C+Kevyn%3BKing%2C+John%3BCantwell%2C+Mark%3BCaprio%2C+Tony%3BAnonymous&rft.aulast=Lohmann&rft.aufirst=Rainer&rft.date=2008-07-01&rft.volume=72&rft.issue=12S&rft.spage=A567&rft.isbn=&rft.btitle=&rft.title=Geochimica+et+Cosmochimica+Acta&rft.issn=00167037&rft_id=info:doi/ L2 - http://www.sciencedirect.com/science/journal/00167037 LA - English DB - GeoRef N1 - Conference title - 18th annual V. M. Goldschmidt conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 2 N1 - PubXState - NY N1 - Last updated - 2012-06-07 N1 - CODEN - GCACAK N1 - SubjectsTermNotLitGenreText - absolute age; air pollution; alkali metals; aromatic hydrocarbons; black carbon; C-14; California; carbon; Cenozoic; cesium; chronology; Coniferales; Cs-137; dates; fires; Gymnospermae; Holocene; hydrocarbons; hydrology; isotopes; Kings Canyon National Park; lacustrine environment; lake sediments; lead; limnology; metals; national parks; organic compounds; Oriole Lake; Pb-210; Plantae; pollution; polycyclic aromatic hydrocarbons; public lands; Quaternary; radioactive isotopes; sediments; Sequoia; Sequoia National Park; sorption; Spermatophyta; Taxodiaceae; trees; Tulare County California; United States; upper Holocene ER - TY - JOUR T1 - Impact of urbanization on water quantity and quality; the need for an integrative watershed modeling approach AN - 50241658; 2009-082918 JF - Water Resources Impact AU - Mohamoud, Yusuf M Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 27 EP - 29 PB - American Water Resources Association, Herndon, VA VL - 10 IS - 4 SN - 1522-3175, 1522-3175 KW - soils KW - hydrology KW - best management practices KW - water quality KW - water supply KW - watersheds KW - decision-making KW - urbanization KW - simulation KW - models KW - environmental management KW - geographic information systems KW - critical load KW - streamflow KW - runoff KW - information systems KW - water resources KW - land use KW - 21:Hydrogeology KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50241658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Resources+Impact&rft.atitle=Impact+of+urbanization+on+water+quantity+and+quality%3B+the+need+for+an+integrative+watershed+modeling+approach&rft.au=Mohamoud%2C+Yusuf+M&rft.aulast=Mohamoud&rft.aufirst=Yusuf&rft.date=2008-07-01&rft.volume=10&rft.issue=4&rft.spage=27&rft.isbn=&rft.btitle=&rft.title=Water+Resources+Impact&rft.issn=15223175&rft_id=info:doi/ L2 - http://www.awra.org/impact/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 5 N1 - PubXState - VA N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - best management practices; critical load; decision-making; environmental management; geographic information systems; hydrology; information systems; land use; models; runoff; simulation; soils; streamflow; urbanization; water quality; water resources; water supply; watersheds ER - TY - JOUR T1 - Phylogenetic Diversity and Molecular Detection of Bacteria in Gull Feces AN - 21479027; 12494580 AB - In spite of increasing public health concerns about the potential risks associated with swimming in waters contaminated with waterfowl feces, little is known about the composition of the gut microbial community of aquatic birds. To address this, a gull 16S rRNA gene clone library was developed and analyzed to determine the identities of fecal bacteria. Analysis of 282 16S rRNA gene clones demonstrated that the gull gut bacterial community is mostly composed of populations closely related to Bacilli (37%), Clostridia (17%), Gammaproteobacteria (11%), and Bacteriodetes (1%). Interestingly, a considerable number of sequences (i.e., 26%) were closely related to Catellicoccus marimammalium, a gram-positive, catalase-negative bacterium. To determine the occurrence of C. marimammalium in waterfowl, species-specific 16S rRNA gene PCR and real-time assays were developed and used to test fecal DNA extracts from different bird (n = 13) and mammal (n = 26) species. The results showed that both assays were specific to gull fecal DNA and that C. marimammalium was present in gull fecal samples collected from the five locations in North America (California, Georgia, Ohio, Wisconsin, and Toronto, Canada) tested. Additionally, 48 DNA extracts from waters collected from six sites in southern California, Great Lakes in Michigan, Lake Erie in Ohio, and Lake Ontario in Canada presumed to be impacted with gull feces were positive by the C. marimammalium assay. Due to the widespread presence of this species in gulls and environmental waters contaminated with gull feces, targeting this bacterial species might be useful for detecting gull fecal contamination in waterfowl-impacted waters. JF - Applied and Environmental Microbiology AU - Lu, Jingrang AU - Santo Domingo, Jorge W AU - Lamendella, Regina AU - Edge, Thomas AU - Hill, Stephen AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, 26 Martin Luther King Drive, MS-387, Cincinnati, Ohio 45268, santodomingo.jorge@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 3969 EP - 3976 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 74 IS - 13 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Bacilli KW - Bacteriodetes KW - Feces KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21479027?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Phylogenetic+Diversity+and+Molecular+Detection+of+Bacteria+in+Gull+Feces&rft.au=Lu%2C+Jingrang%3BSanto+Domingo%2C+Jorge+W%3BLamendella%2C+Regina%3BEdge%2C+Thomas%3BHill%2C+Stephen&rft.aulast=Lu&rft.aufirst=Jingrang&rft.date=2008-07-01&rft.volume=74&rft.issue=13&rft.spage=3969&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00019-08 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Feces; Bacteriodetes DO - http://dx.doi.org/10.1128/AEM.00019-08 ER - TY - JOUR T1 - Second Announcement: 29th Symposium on Sea Turtle Biology and Conservation, Brisbane, Australia, 17-19 February 2009 AN - 21059754; 8565409 AB - Preparations for the 29 super(th) Symposium on Sea Turtle Biology and Conservation in Brisbane are in full swing. The scientific session titles axe set, the various associated meetings are lined up, and the social events are going to be a whole lot of fun. JF - Marine Turtle Newsletter AU - Limpus, C AU - Schauble, C AD - International Sea Turtle Society c/o, Queensland Environmental Protection Agency, Brisbane, Australia, brisbane2009@seaturtle.org Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 34 EP - 35 IS - 121 SN - 0839-7708, 0839-7708 KW - Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Marine KW - Conferences KW - Aquatic reptiles KW - ISEW, Australia, Queensland, Brisbane KW - Australia KW - Q5 08523:Conservation, wildlife management and recreation KW - O 4090:Conservation and Environmental Protection KW - Q1 08423:Behaviour UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21059754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Turtle+Newsletter&rft.atitle=Second+Announcement%3A+29th+Symposium+on+Sea+Turtle+Biology+and+Conservation%2C+Brisbane%2C+Australia%2C+17-19+February+2009&rft.au=Limpus%2C+C%3BSchauble%2C+C&rft.aulast=Limpus&rft.aufirst=C&rft.date=2008-07-01&rft.volume=&rft.issue=121&rft.spage=34&rft.isbn=&rft.btitle=&rft.title=Marine+Turtle+Newsletter&rft.issn=08397708&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Conferences; Aquatic reptiles; ISEW, Australia, Queensland, Brisbane; Australia; Marine ER - TY - JOUR T1 - Catfish consumption as a contributor to elevated PCB levels in a non-Hispanic black subpopulation AN - 20945172; 8259941 AB - The human body burden of polychlorinated biphenyls (PCBs) sharply declined after production was banned in the US in 1979. For the 10% of the US population that remains most exposed to PCBs, fish consumption is the primary source. National Health and Nutrition Examination Survey (NHANES) data indicates that the highest remaining PCB levels exist in a non-Hispanic black subpopulation. Our review suggests that catfish consumption may be a significant PCB source for the one million non-Hispanic black anglers who fish for catfish. In comparison to non-Hispanic white anglers, non-Hispanic black anglers consume more catfish, are more likely to eat the whole fish rather than just the fillets that contain less PCBs, and are more likely to fish in watersheds with high PCB contamination. Efforts to diminish potential racial disparities in PCB exposure are challenged by geographic, economic, cultural, and educational barriers. In response, we propose that a fish consumption survey be performed that identifies the extent of subsistence fishing by non-Hispanic black anglers for catfish in watersheds with PCB contamination, the type and quantity of catfish subsistence fishing provides, and what actions would help moderate PCB exposure due to subsistence fishing for catfish in such areas. Understanding the contamination and consumption factors that contribute to higher PCB body burdens will help identify and offer solutions to racial disparities in exposure to PCBs due to subsistence fishing while providing a model to prevent similar disparities in exposure to toxics ranging from mercury to polybrominated diphenyl ethers. JF - Environmental Research AU - Weintraub, M AU - Birnbaum, L S AD - Communities and Ecosystems Division, 75 Hawthorne Street (CED-4), San Francisco, CA 94105, USA, weintraub.max@epa.gov Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 412 EP - 417 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 107 IS - 3 SN - 0013-9351, 0013-9351 KW - Pollution Abstracts; Aqualine Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Toxicology Abstracts; Water Resources Abstracts KW - Contamination KW - Watersheds KW - Toxicity tests KW - Public health KW - Fish consumption KW - Exposure KW - Economics KW - Pollution indicators KW - PCB KW - Subpopulations KW - polybrominated diphenyl ethers KW - polychlorinated biphenyls KW - Water Pollution Effects KW - Mercury KW - Fish KW - culture KW - Polychlorinated Biphenyls KW - Nutrition KW - Models KW - Sport fishing KW - Polybrominated diphenyl ethers KW - Fishing KW - body burden KW - PCB compounds KW - Body burden KW - Fishermen KW - Toxicity KW - Bioaccumulation KW - subpopulations KW - Reviews KW - Catfish KW - fishing KW - Q5 08503:Characteristics, behavior and fate KW - P 2000:FRESHWATER POLLUTION KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - Q1 08425:Nutrition and feeding habits KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20945172?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Research&rft.atitle=Catfish+consumption+as+a+contributor+to+elevated+PCB+levels+in+a+non-Hispanic+black+subpopulation&rft.au=Weintraub%2C+M%3BBirnbaum%2C+L+S&rft.aulast=Weintraub&rft.aufirst=M&rft.date=2008-07-01&rft.volume=107&rft.issue=3&rft.spage=412&rft.isbn=&rft.btitle=&rft.title=Environmental+Research&rft.issn=00139351&rft_id=info:doi/10.1016%2Fj.envres.2008.03.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Body burden; Fish consumption; Fishermen; Watersheds; Pollution indicators; Toxicity tests; PCB; Sport fishing; Public health; Fishing; polybrominated diphenyl ethers; polychlorinated biphenyls; Contamination; Reviews; Subpopulations; Economics; Mercury; Nutrition; Models; Polybrominated diphenyl ethers; subpopulations; body burden; fishing; PCB compounds; culture; Bioaccumulation; Exposure; Water Pollution Effects; Polychlorinated Biphenyls; Fish; Toxicity; Catfish DO - http://dx.doi.org/10.1016/j.envres.2008.03.001 ER - TY - JOUR T1 - Stochastic Residual-Error Analysis for Estimating Hydrologic Model Predictive Uncertainty AN - 20918764; 8349162 AB - A hybrid time series-nonparametric sampling approach, referred to herein as semiparametric, is presented for the estimation of model predictive uncertainty. The methodology is a two-step procedure whereby a distributed hydrologic model is first calibrated, then followed by brute force application of time series analysis with nonparametric random generation to synthesize serially correlated model residual errors. The methodology is applied to estimate uncertainties in simulated streamflows and related flow attributes upstream from the mouth of a rapidly urbanizing watershed. Two procedures for the estimation of model output uncertainty are compared: the Gaussian-based l-step forecast and the semiparametric ensemble forecast. Results show that although both methods yielded comparable uncertainty bands, the Gaussian l-step forecast underestimated the width of the uncertainty band when compared to the semiparametric method. An ensemble of streamflows generated through Latin-hypercube Monte Carlo simulations showed relatively larger values of the coefficient of variation for long-term average annual maximum daily flows than for long-term daily, monthly maximum daily, and monthly median of daily flows. Ensemble of flow duration curves is generated from the error-adjusted simulated flows. The computed low flows displayed greater values of the coefficient of variation than flows in the medium and high range. The ensemble flow durations allow for the estimation of daily flow range upstream from the outlet with 95% confidence for a specified design recurrence period. The computed uncertainties of the predicted watershed response and associated flow attributes provide the basis for communicating the risk to stakeholders and decision makers who are involved in the future development of the watershed. JF - Journal of Hydrologic Engineering AU - Hantush, M M AU - Kalin, L AD - U.S. EPA NRMRL, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA, hantush.mohamed@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 585 EP - 596 VL - 13 IS - 7 SN - 1084-0699, 1084-0699 KW - Aqualine Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts KW - Prediction KW - Outlets KW - Statistical analysis KW - Monte Carlo method KW - Freshwater KW - Watersheds KW - Time series analysis KW - Time Series Analysis KW - Hydrologic Models KW - Flow duration curves KW - Statistical Analysis KW - Hydrology KW - Sampling KW - Hydrologic models KW - Mathematical models KW - Stochastic models in hydrology KW - Ensemble forecasting KW - Streamflow KW - Stochastic methods in hydrology KW - Risk KW - Numerical simulations KW - Flow Duration KW - M2 556:General (556) KW - Q2 09171:Dynamics of lakes and rivers KW - SW 6010:Structures KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20918764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hydrologic+Engineering&rft.atitle=Stochastic+Residual-Error+Analysis+for+Estimating+Hydrologic+Model+Predictive+Uncertainty&rft.au=Hantush%2C+M+M%3BKalin%2C+L&rft.aulast=Hantush&rft.aufirst=M&rft.date=2008-07-01&rft.volume=13&rft.issue=7&rft.spage=585&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hydrologic+Engineering&rft.issn=10840699&rft_id=info:doi/10.1061%2F%28ASCE%291084-0699%282008%2913%3A7%28585%29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-08-19 N1 - SubjectsTermNotLitGenreText - Prediction; Mathematical models; Statistical analysis; Hydrology; Time series analysis; Watersheds; Flow duration curves; Numerical simulations; Stochastic models in hydrology; Ensemble forecasting; Monte Carlo method; Stochastic methods in hydrology; Hydrologic models; Risk; Time Series Analysis; Outlets; Hydrologic Models; Flow Duration; Statistical Analysis; Streamflow; Sampling; Freshwater DO - http://dx.doi.org/10.1061/(ASCE)1084-0699(2008)13:7(585) ER - TY - JOUR T1 - Undertaking positive control studies as part of developmental neurotoxicity testing AN - 20823792; 8347685 AB - Developmental neurotoxicity testing involves functional and neurohistological assessments in offspring during and following maternal and/or neonatal exposure. Data from positive control studies are an integral component in developmental neurotoxicity risk assessments. Positive control data are crucial for evaluating a laboratory's capability to detect chemical-induced changes in measured endpoints. Positive control data are also valuable in a weight-of-evidence approach to help determine the biological significance of results and provide confidence in negative results from developmental neurotoxicity (DNT) studies. This review is a practical guide for the selection and use of positive control agents in developmental neurotoxicology. The advantages and disadvantages of various positive control agents are discussed for the endpoints in developmental neurotoxicity studies. Design issues specific to positive control studies in developmental neurotoxicity are considered and recommendations on how to interpret and report positive control data are made. Positive control studies should be conducted as an integral component of the incorporation and use of developmental neurotoxicity testing methods in laboratories that generate data used in risk decisions. JF - Neurotoxicology and Teratology AU - Crofton, K M AU - Foss, JA AU - Hass, U AU - Jensen, K F AU - Levin, ED AU - Parker, S P AD - NHEERL, ORD, US EPA, Research Triangle Park, NC, United States, crofton.kevin@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 266 EP - 287 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 30 IS - 4 SN - 0892-0362, 0892-0362 KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - Risk assessment KW - Data processing KW - Reviews KW - Neurotoxicity KW - Progeny KW - Neonates KW - N3 11028:Neuropharmacology & toxicology KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20823792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Undertaking+positive+control+studies+as+part+of+developmental+neurotoxicity+testing&rft.au=Crofton%2C+K+M%3BFoss%2C+JA%3BHass%2C+U%3BJensen%2C+K+F%3BLevin%2C+ED%3BParker%2C+S+P&rft.aulast=Crofton&rft.aufirst=K&rft.date=2008-07-01&rft.volume=30&rft.issue=4&rft.spage=266&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2007.06.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Data processing; Reviews; Neurotoxicity; Progeny; Neonates DO - http://dx.doi.org/10.1016/j.ntt.2007.06.002 ER - TY - JOUR T1 - Physiologically based Pharmacokinetic Modeling of Chloroethane Disposition in Mice, Rats, and Women AN - 20822353; 8305261 AB - Chloroethane was observed in a chronic cancer bioassay to be a mouse-specific uterine carcinogen at a single high inhaled concentration (15,000 ppm). Although high incidence occurred in the female mouse (86%), no uterine tumor increases were observed in female rats. Chloroethane is a weak alkylating agent and has low acute toxicity. No genotoxicity potential has been observed below 40,000 ppm. Chloroethane is eliminated from the body by pulmonary exhalation and metabolically by oxidation via cytochrome P-450 (likely producing acetaldehyde) and conjugation with glutathione (GSH). The mode of action for the mouse-specific uterine tumors is not definitively known and could involve parent chemical and/or metabolite(s). A physiologically based pharmacokinetic (PBPK) model for chloroethane disposition in the rat was developed previously, but no such models have been described for mice or humans. For the work reported here, the existing PBPK model for chloroethane in rats was expanded and refined, and PBPK models for chloroethane disposition in mice and humans were developed to allow species comparisons of internal dosimetry and for possible insights into the carcinogenic mode of action. The amounts metabolized via glutathione-S-transferase (GST) versus cytochrome P-450, and the total amount of chloroethane absorbed, were most consistent with the observations made concerning uterine tumors, with amounts metabolized via GST providing the larger quantitative difference between the two rodent species. Choice of the most relevant dose metric for risk assessments involving uterine tumors in mice will require pharmacodynamic considerations in the mode of action in addition to the pharmacokinetic differences reported here. JF - Toxicological Sciences AU - Gargas, Michael L AU - Sweeney, Lisa M AU - Himmelstein, Matthew W AU - Pottenger, Lynn H AU - Bus, James S AU - Holder, James W AD - The Sapphire Group, Inc., Dayton, Ohio 45431. DuPont Haskell Laboratory, Newark, Delaware 19714. Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, Michigan 48674. National Center for Environmental Assessment, Office of Research and Development, U.S. EPA, Washington, D.C. 20004 Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 54 EP - 66 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 104 IS - 1 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Alkylating agents KW - Risk assessment KW - Cytochromes KW - Uterus KW - Glutathione KW - Acetaldehyde KW - Genotoxicity KW - Dosimetry KW - Animal models KW - Disposition KW - Acute toxicity KW - Carcinogens KW - Tumors KW - Glutathione transferase KW - Cancer KW - Pharmacokinetics KW - Lung KW - Oxidation KW - Uterine cancer KW - Pharmacodynamics KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20822353?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Physiologically+based+Pharmacokinetic+Modeling+of+Chloroethane+Disposition+in+Mice%2C+Rats%2C+and+Women&rft.au=Gargas%2C+Michael+L%3BSweeney%2C+Lisa+M%3BHimmelstein%2C+Matthew+W%3BPottenger%2C+Lynn+H%3BBus%2C+James+S%3BHolder%2C+James+W&rft.aulast=Gargas&rft.aufirst=Michael&rft.date=2008-07-01&rft.volume=104&rft.issue=1&rft.spage=54&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Alkylating agents; Cytochromes; Uterus; Glutathione; Acetaldehyde; Dosimetry; Genotoxicity; Animal models; Disposition; Tumors; Carcinogens; Acute toxicity; Glutathione transferase; Pharmacokinetics; Cancer; Lung; Oxidation; Uterine cancer; Pharmacodynamics ER - TY - JOUR T1 - Stream Condition and Infant Mortality in U.S. Mid-Atlantic States AN - 20791559; 10310271 AB - Infant mortality rate (IMR) serves as a summary measure of the health of a nation's population. The U.S. IMR has declined over the past several decades (to 6.85 per 1000 in 2003), but remains high compared with other developed countries. We hypothesized a relationship between IMR and poor water quality at a local scale. We used degraded stream condition, represented by a multimetric index of biotic condition, as a metric for poor water quality. Using conditional probability analysis on county-aggregated data for the state of Maryland, we show that there is a significant association between the extent of a county's stream miles in poor ecological condition and the probability of a county's IMR exceeding the national norm. The overall relationship appears to be robust, as similar associations were also found for the states of West Virginia and Pennsylvania. We are not implying that IMR and degraded stream condition are directly causally related, but rather that there may be common factors that affect both of them. We hypothesize that attributes and activities at the county scale (e.g., socioeconomic conditions, land use, human activities) may contribute to both stream degradation and increased IMR. JF - Human and Ecological Risk Assessment AU - Paul, John AU - McDonald, Michael AU - Hedtke, Steven AD - National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA Y1 - 2008/07// PY - 2008 DA - July 2008 SP - 728 EP - 741 PB - Taylor & Francis Group Ltd., 2 Park Square Milton Park, Abingdon Oxford OX14 4RN UK VL - 14 IS - 4 SN - 1080-7039, 1080-7039 KW - Pollution Abstracts; Sustainability Science Abstracts; Risk Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Land Use KW - Risk assessment KW - water quality KW - infant mortality KW - Degradation KW - Socioeconomics KW - Man-induced effects KW - Freshwater KW - Water quality KW - Streams KW - Stream Degradation KW - Public health KW - Assessments KW - Stream Pollution KW - USA, Maryland KW - Mortality KW - Water Quality KW - USA, West Virginia KW - Land use KW - Risk KW - USA, Pennsylvania KW - Human factors KW - Environmental conditions KW - Mortality causes KW - developed countries KW - M3 1010:Issues in Sustainable Development KW - SW 3010:Identification of pollutants KW - P 2000:FRESHWATER POLLUTION KW - R2 23050:Environment KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20791559?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+and+Ecological+Risk+Assessment&rft.atitle=Stream+Condition+and+Infant+Mortality+in+U.S.+Mid-Atlantic+States&rft.au=Paul%2C+John%3BMcDonald%2C+Michael%3BHedtke%2C+Steven&rft.aulast=Paul&rft.aufirst=John&rft.date=2008-07-01&rft.volume=14&rft.issue=4&rft.spage=728&rft.isbn=&rft.btitle=&rft.title=Human+and+Ecological+Risk+Assessment&rft.issn=10807039&rft_id=info:doi/10.1080%2F10807030802235144 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Man-induced effects; Environmental conditions; Water quality; Land use; Mortality causes; Public health; Risk assessment; water quality; Degradation; infant mortality; Socioeconomics; Human factors; Streams; developed countries; Land Use; Risk; Mortality; Assessments; Water Quality; Stream Pollution; Stream Degradation; USA, Pennsylvania; USA, West Virginia; USA, Maryland; Freshwater DO - http://dx.doi.org/10.1080/10807030802235144 ER - TY - JOUR T1 - Developmental Exposure to Perchlorate Alters Synaptic Transmission in Hippocampus of the Adult Rat AN - 20244864; 8306975 AB - Background: Perchlorate is an environmental contaminant that blocks iodine uptake into the thyroid gland and reduces thyroid hormones. This action of perchlorate raises significant concern over its effects on brain development. Objectives: The purpose of this study was to evaluate neurologic function in rats after developmental exposure to perchlorate. Methods: Pregnant rats were exposed to 0, 30, 300, or 1,000 ppm perchlorate in drinking water from gestational day 6 until weaning. Adult male offspring were evaluated on a series of behavioral tasks and neurophysiologic measures of synaptic function in the hippocampus. Results: At the highest perchlorate dose, triiodothyronine (T sub(3)) and thyroxine (T sub(4)) were reduced in pups on postnatal day 21. T sub(4) in dams was reduced relative to controls by 16%, 28%, and 60% in the 30-, 300-, and 1,000-ppm dose groups, respectively. Reductions in T sub(4) were associated with increases in thyroid-stimulating hormone in the high-dose group. No changes were seen in serum T sub(3). Perchlorate did not impair motor activity, spatial learning, or fear conditioning. However, significant reductions in baseline synaptic transmission were observed in hippocampal field potentials at all dose levels. Reductions in inhibitory function were evident at 300 and 1,000 ppm, and augmentations in long-term potentiation were observed in the population spike measure at the highest dose. Conclusions: Dose-dependent deficits in hippocampal synaptic function were detectable with relatively minor perturbations of the thyroid axis, indicative of an irreversible impairment in synaptic transmission in response to developmental exposure to perchlorate. JF - Environmental Health Perspectives AU - Gilbert, ME AU - Sui, L AD - Neurotoxicology Division (MD-B105-05), National Health and Environmental Effects Research Laboratory, 109 TW Alexander Dr., U.S. EPA, Research Triangle Park, NC 27711 USA, gilbert.mary@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 752 EP - 760 VL - 116 IS - 6 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts; Environment Abstracts KW - Hippocampus KW - Weaning KW - Hormones KW - Rats KW - Thyroid hormones KW - Dams KW - Motor activity KW - Long-term potentiation KW - Thyroxine KW - Iodine KW - Thyroid-stimulating hormone KW - Spatial discrimination learning KW - Motor skill learning KW - offspring KW - Thyroid KW - Brain KW - Triiodothyronine KW - Fear conditioning KW - Firing pattern KW - perchlorate KW - Pregnancy KW - spatial memory KW - Progeny KW - Synaptic transmission KW - Perchloric acid KW - Contaminants KW - Drinking water KW - X 24350:Industrial Chemicals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20244864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developmental+Exposure+to+Perchlorate+Alters+Synaptic+Transmission+in+Hippocampus+of+the+Adult+Rat&rft.au=Gilbert%2C+ME%3BSui%2C+L&rft.aulast=Gilbert&rft.aufirst=ME&rft.date=2008-07-01&rft.volume=116&rft.issue=6&rft.spage=752&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.11089 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Hippocampus; Brain; Weaning; Triiodothyronine; Fear conditioning; Firing pattern; Pregnancy; spatial memory; Thyroid hormones; Motor activity; Thyroxine; Long-term potentiation; Iodine; Progeny; Perchloric acid; Synaptic transmission; Thyroid-stimulating hormone; Spatial discrimination learning; Drinking water; Contaminants; Motor skill learning; Rats; Dams; Thyroid; Hormones; perchlorate; offspring DO - http://dx.doi.org/10.1289/ehp.11089 ER - TY - JOUR T1 - Recent Advances and Opportunities in Research on Lupus: Environmental Influences and Mechanisms of Disease AN - 20228601; 8306966 AB - Objectives: In this review we summarize research on mechanisms through which environmental agents may affect the pathogenesis of lupus, discuss three exposures that have been the focus of research in this area, and propose recommendations for new research initiatives. Data sources and Synthesis: We examined studies pertaining to key mechanistic events and specific exposures. Apoptosis leading to increased production or decreased clearance of immuno-genic intracellular self-antigens and defective apoptosis of autoreactive immune cells both have been implicated in the loss of self-tolerance. The adjuvant or bystander effect is also needed to produce a sustained autoimmune response. Activation of toll-like receptors is one mechanism through which these effects may occur. Abnormal DNA methylation may also contribute to the pathogenesis of lupus. Each of the specific exposures we examined--Epstein-Barr virus, silica, and trichloroethylene--has been shown, in humans or in mice, to act upon one or more of these pathogenic steps. Specific recommendations for the continued advancement of our understanding of environmental influences on lupus and other autoimmune diseases include the development and use of mouse models with varying degrees of penetrance and manifestations of disease, identification of molecular or physiologic targets of specific exposures, development and use of improved exposure assessment methodologies, and multisite collaborations designed to examine understudied environmental exposures in humans. Conclusions: The advances made in the past decade concerning our understanding of mechanisms involved in the development of lupus and the influence of environmental agents on this process provide a strong foundation for further developments in this field. JF - Environmental Health Perspectives AU - Cooper, G S AU - Gilbert, K M AU - Greidinger, EL AU - James, JA AU - Pfau, J C AU - Reinlib, L AU - Richardson, B C AU - Rose, N R AD - National Center for Environmental Assessment 8601-P, U.S. Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460 USA, cooper.glinda@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 695 EP - 702 VL - 116 IS - 6 SN - 0091-6765, 0091-6765 KW - lupus KW - Virology & AIDS Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Environment Abstracts KW - Adjuvants KW - Animal models KW - Environmental health KW - V 22410:Animal Diseases KW - N 14820:DNA Metabolism & Structure KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20228601?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Recent+Advances+and+Opportunities+in+Research+on+Lupus%3A+Environmental+Influences+and+Mechanisms+of+Disease&rft.au=Cooper%2C+G+S%3BGilbert%2C+K+M%3BGreidinger%2C+EL%3BJames%2C+JA%3BPfau%2C+J+C%3BReinlib%2C+L%3BRichardson%2C+B+C%3BRose%2C+N+R&rft.aulast=Cooper&rft.aufirst=G&rft.date=2008-07-01&rft.volume=116&rft.issue=6&rft.spage=695&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.11092 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Animal models; Environmental health DO - http://dx.doi.org/10.1289/ehp.11092 ER - TY - JOUR T1 - Stachybotrys chartarum, Trichothecene Mycotoxins, and Damp Building-Related Illness: New Insights into a Public Health Enigma AN - 20025792; 8305260 AB - Damp building-related illnesses (DBRI) include a myriad of respiratory, immunologic, and neurologic symptoms that are sometimes etiologically linked to aberrant indoor growth of the toxic black mold, Stachybotrys chartarum. Although supportive evidence for such linkages is limited, there are exciting new findings about this enigmatic organism relative to its environmental dissemination, novel bioactive components, unique cellular targets, and molecular mechanisms of action which provide insight into the S. chartarum's potential to evoke allergic sensitization, inflammation, and cytotoxicity in the upper and lower respiratory tracts. Macrocyclic trichothecene mycotoxins, produced by one chemotype of this fungus, are potent translational inhibitors and stress kinase activators that appear to be a critical underlying cause for a number of adverse effects. Notably, these toxins form covalent protein adducts in vitro and in vivo and, furthermore, cause neurotoxicity and inflammation in the nose and brain of the mouse. A second S. chartarum chemotype has recently been shown to produce atranones-mycotoxins that can induce pulmonary inflammation. Other biologically active products of this fungus that might contribute to pathophysiologic effects include proteinases, hemolysins, beta -glucan, and spirocyclic drimanes. Solving the enigma of whether Stachybotrys inhalation indeed contributes to DBRI will require studies of the pathophysiologic effects of low dose chronic exposure to well-characterized, standardized preparations of S. chartarum spores and mycelial fragments, and, coexposures with other environmental cofactors. Such studies must be linked to improved assessments of human exposure to this fungus and its bioactive constituents in indoor air using both state-of-the-art sampling/analytical methods and relevant biomarkers. JF - Toxicological Sciences AU - Pestka, James J AU - Yike, Iwona AU - Dearborn, Dorr G AU - Ward, Marsha DW AU - Harkema, Jack R AD - Center for Integrative Toxicology. Department of Microbiology and Molecular Genetics. Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan 48824. Department of Environmental Health Sciences, Case Western Reserve University, Cleveland, Ohio 44106. U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711. Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan 48824 Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 4 EP - 26 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 104 IS - 1 SN - 1096-6080, 1096-6080 KW - Pollution Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts C: Algology, Mycology & Protozoology; Health & Safety Science Abstracts; Toxicology Abstracts KW - Inhalation KW - Molecular modelling KW - Translation KW - Molds KW - trichothecenes KW - Public health KW - Chronic exposure KW - Proteinase KW - Sampling KW - Hemolysins KW - Respiratory tract KW - Bioindicators KW - Brain KW - Stress KW - Stachybotrys chartarum KW - Mycelia KW - biomarkers KW - Toxins KW - Inflammation KW - beta -Glucan KW - Cytotoxicity KW - Mycotoxins KW - Cofactors KW - Stachybotrys KW - Protein adducts KW - Lung KW - Neurotoxicity KW - Proteins KW - Standards KW - Nose KW - Indoor environments KW - Spores KW - Side effects KW - K 03330:Biochemistry KW - P 0000:AIR POLLUTION KW - X 24370:Natural Toxins KW - A 01450:Environmental Pollution & Waste Treatment KW - H 14000:Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20025792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Stachybotrys+chartarum%2C+Trichothecene+Mycotoxins%2C+and+Damp+Building-Related+Illness%3A+New+Insights+into+a+Public+Health+Enigma&rft.au=Pestka%2C+James+J%3BYike%2C+Iwona%3BDearborn%2C+Dorr+G%3BWard%2C+Marsha+DW%3BHarkema%2C+Jack+R&rft.aulast=Pestka&rft.aufirst=James&rft.date=2008-07-01&rft.volume=104&rft.issue=1&rft.spage=4&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Inhalation; Translation; Molecular modelling; Molds; trichothecenes; Public health; Chronic exposure; Proteinase; Sampling; Hemolysins; Respiratory tract; Brain; Mycelia; biomarkers; Inflammation; beta -Glucan; Mycotoxins; Cytotoxicity; Cofactors; Lung; Protein adducts; Neurotoxicity; Nose; Spores; Side effects; Bioindicators; Stress; Toxins; Proteins; Standards; Indoor environments; Stachybotrys; Stachybotrys chartarum ER - TY - JOUR T1 - Signals from the benthos: Development and evaluation of a benthic index for the nearshore Gulf of Maine AN - 19679835; 8286469 AB - We developed a benthic index for the nearshore Gulf of Maine to provide researchers and environmental managers a way to make spatial and year-to-year comparisons of benthic condition. The data set used included 248 stations sampled for physical, chemical, and biological variables by the National Coastal Assessment in 2000-2003. We used logistic regression with 49 candidate measures of benthic species diversity, pollution sensitivity-tolerance, and community composition to discriminate sites with high and low benthic environmental quality (BEQ). BEQ was based on the concentrations of metal and organic contaminants in the sediments, total organic carbon, sediment toxicity, and dissolved oxygen level of the bottom water. An analysis of similarity test showed that the community composition of low BEQ stations was significantly different (p<0.001) from high BEQ stations. Ten of the 49 benthic metrics showed a strong ability to discriminate stations. We developed several candidate benthic indices and tested them with independent data from Massachusetts Bay and Casco Bay to help select and validate the best index. A model using the Shannon-Wiener diversity measure, Rosenberg's species pollution tolerance measure, and the percent capitellid polychaetes (or percent Capitella spp.) strongly discriminated stations, with an area under the receiver operating characteristic (ROC) curve of 0.82 and a classification accuracy of 80%. Signal detection theory (ROC curves and positive-negative predictive value curves) was used to evaluate the index and to predict how well an index developed for one geographic area might work in another area with a different prevalence of the degraded condition. We show how these techniques can also guide decisions by environmental managers about choosing thresholds and weighing costs and benefits of particular actions. JF - Ecological Indicators AU - Hale, S S AU - Heltshe, J F AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, 27 Tarzwell Drive, Narragansett, RI 02882, USA, hale.stephen@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 338 EP - 350 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 8 IS - 4 SN - 1470-160X, 1470-160X KW - Pollution Abstracts; Sustainability Science Abstracts; Ecology Abstracts KW - ANW, USA, Maine Gulf KW - Dissolved oxygen KW - environmental management KW - Classification KW - Pollution tolerance KW - Metals KW - Community composition KW - Capitella KW - ANW, USA, Massachusetts, Massachusetts Bay KW - Environmental quality KW - Contaminants KW - Benthos KW - Models KW - Cost-benefit analysis KW - Total organic carbon KW - Sediment pollution KW - Toxicity KW - Sediments KW - ANW, USA, Maine, Casco Bay KW - classification KW - Species diversity KW - Casco KW - D 04070:Pollution KW - M3 1010:Issues in Sustainable Development KW - P 1000:MARINE POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19679835?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Indicators&rft.atitle=Signals+from+the+benthos%3A+Development+and+evaluation+of+a+benthic+index+for+the+nearshore+Gulf+of+Maine&rft.au=Hale%2C+S+S%3BHeltshe%2C+J+F&rft.aulast=Hale&rft.aufirst=S&rft.date=2008-07-01&rft.volume=8&rft.issue=4&rft.spage=338&rft.isbn=&rft.btitle=&rft.title=Ecological+Indicators&rft.issn=1470160X&rft_id=info:doi/10.1016%2Fj.ecolind.2007.04.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Casco; Capitella; ANW, USA, Maine Gulf; ANW, USA, Maine, Casco Bay; ANW, USA, Massachusetts, Massachusetts Bay; Toxicity; environmental management; Sediment pollution; Community composition; Sediments; Dissolved oxygen; Metals; Cost-benefit analysis; Environmental quality; Total organic carbon; Benthos; Species diversity; Pollution tolerance; classification; Contaminants; Classification; Models DO - http://dx.doi.org/10.1016/j.ecolind.2007.04.004 ER - TY - JOUR T1 - Changes to Dauphin Island, Alabama, Brought about by Hurricane Katrina (August 29, 2005) AN - 19588235; 8698259 AB - On the morning of August 29, 2005, Hurricane Katrina (a Category 3 hurricane on the Saffir-Simpson scale) made landfall in southeastern Louisiana. Although Dauphin Island, Alabama, is located approximately 180 km to the northeast of where Katrina made landfall, it experienced greater coastal damage than from recent Category 3 hurricanes that were closer to the island (e.g., Frederic in 1979 and Ivan in 2004). This is because the island was within the most intense area of the hurricane as it approached land (i.e., the top-right quadrant). The gulf side of Dauphin Island was impacted by a storm surge of 1.94 m coupled with even higher storm waves. Pelican-Sand Island, to the south of the eastern portion of the island, absorbed much of the storm wave energy, resulting in a lessening of storm water damage to this segment of Dauphin Island. The elevated storm surge and diminished storm waves carried plant debris and sand tens of meters landward across this portion of Dauphin Island. Conversely, with no offshore protection, much of the low-lying western section of the island was completely overwashed. In addition, numerous channels were cut through this section of the island. The greatest change to Dauphin Island was the creation of a 2.0-km wide channel cut through a segment of the undeveloped western end of the island. Hurricane Katrina demonstrated once again the island's fragile nature and precarious setting in the northern Gulf of Mexico. JF - Journal of Coastal Research AU - Froede, Carl R AD - U.S. Environmental Protection Agency, Region 4, 61 Forsyth Street, Atlanta, GA 30303-8960, U.S.A Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 110 EP - 117 PB - Allen Press, Inc., 810 East Tenth St. VL - 24 IS - sp3 SN - 0749-0208, 0749-0208 KW - Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Dauphin Island KW - Hurricane Katrina KW - overwash KW - beach erosion KW - channel cuts KW - island scour KW - ASW, USA, Louisiana KW - Coastal research KW - Gulfs KW - Storms KW - Storm Water KW - Islands KW - Sand KW - Storm Surges KW - Wave energy KW - Waves KW - Coastal inlets KW - Detritus KW - Damage KW - ASW, USA, Alabama, Dauphin I. KW - wave energy KW - ASW, Mexico Gulf KW - Channels KW - Hurricanes KW - Storm surges KW - Storm waves KW - M2 551.515.2:Cyclones Hurricanes Typhoons (551.515.2) KW - M3 1010:Issues in Sustainable Development KW - SW 0810:General KW - Q2 09170:Nearshore dynamics KW - Q5 08522:Protective measures and control KW - O 6020:Offshore Engineering and Operations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19588235?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Coastal+Research&rft.atitle=Changes+to+Dauphin+Island%2C+Alabama%2C+Brought+about+by+Hurricane+Katrina+%28August+29%2C+2005%29&rft.au=Froede%2C+Carl+R&rft.aulast=Froede&rft.aufirst=Carl&rft.date=2008-07-01&rft.volume=24&rft.issue=sp3&rft.spage=110&rft.isbn=&rft.btitle=&rft.title=Journal+of+Coastal+Research&rft.issn=07490208&rft_id=info:doi/10.2112%2F06-0782.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Hurricanes; Storm surges; Wave energy; Coastal inlets; Coastal research; Storms; Storm waves; Channels; Islands; Sand; wave energy; Storm Water; Damage; Storm Surges; Waves; Detritus; Gulfs; ASW, Mexico Gulf; ASW, USA, Louisiana; ASW, USA, Alabama, Dauphin I. DO - http://dx.doi.org/10.2112/06-0782.1 ER - TY - JOUR T1 - Effects of using the CB05 vs. SAPRC99 vs. CB4 chemical mechanism on model predictions: Ozone and gas-phase photochemical precursor concentrations AN - 19475711; 8375786 AB - A three-dimensional air quality model is used to examine the magnitude and spatial distribution of differences in predictions among three chemical mechanisms that are used for regulatory and research modeling. The Carbon Bond mechanism CB05 is compared to an earlier version, CB4, to assess how much changes due to an update might potentially affect previous model conclusions on ozone concentrations and behavior. SAPRC-99 is compared to identify differences that might be expected between two more recent mechanisms, namely CB05 and SAPRC-99. The predicted ozone concentrations are similar for most of the United States, but statistically significant differences occur over many urban areas and the central US. SAPRC-99 predicts higher concentrations than CB05 on average, and both predict higher ozone than CB4. The difference in ozone predictions depends on location, the VOC/NO sub(x) ratio and concentrations of precursor pollutants. We highlight where the largest differences occur, give some explanation for why they occur, and discuss the effect of differences on model applications. JF - Atmospheric Environment AU - Luecken, D J AU - Phillips, S AU - Sarwar, G AU - Jang, C AD - 109 T.W. Alexander Drive, Mail Drop E243-03, Research Triangle Park, NC 27709, USA, luecken.deborah@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 5805 EP - 5820 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 23 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Pollution monitoring KW - Atmospheric pollution models KW - Spatial distribution KW - Statistical analysis KW - Air quality KW - spatial distribution KW - Ozone in troposphere KW - Atmospheric chemistry models KW - Ozone concentration KW - Ozone KW - Urban areas KW - Air quality models KW - USA KW - Air pollution forecasting KW - Photochemicals KW - Volatile organic compounds KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19475711?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Effects+of+using+the+CB05+vs.+SAPRC99+vs.+CB4+chemical+mechanism+on+model+predictions%3A+Ozone+and+gas-phase+photochemical+precursor+concentrations&rft.au=Luecken%2C+D+J%3BPhillips%2C+S%3BSarwar%2C+G%3BJang%2C+C&rft.aulast=Luecken&rft.aufirst=D&rft.date=2008-07-01&rft.volume=42&rft.issue=23&rft.spage=5805&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.08.056 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Ozone in troposphere; Atmospheric pollution models; Spatial distribution; Atmospheric chemistry models; Statistical analysis; Ozone concentration; Air quality models; spatial distribution; Pollution monitoring; Air pollution forecasting; Photochemicals; Air quality; Volatile organic compounds; Urban areas; Ozone; USA DO - http://dx.doi.org/10.1016/j.atmosenv.2007.08.056 ER - TY - JOUR T1 - A comparison of CMAQ HONO predictions with observations from the Northeast Oxidant and Particle Study AN - 19472297; 8375791 AB - Predictions of nitrous acid from the Community Multiscale Air Quality modeling system are compared with the measurements from the 2001 Northeast Oxidant and Particle Study. Four different sources of nitrous acid were considered in the study: gas-phase reactions, direct emissions, a heterogeneous reaction, and a surface photolysis reaction. When only gas-phase reactions were considered in the model, the diurnally averaged mean bias, the normalized mean bias, the root mean square error, and the normalized mean error of the model were -1.01ppbv, -98%, 1.05ppbv, and 98%, respectively. However, the diurnally averaged mean bias, normalized mean bias, the root mean square error, and the normalized mean error of the model improved to -0.42ppbv, -41%, 0.45ppbv, and 41%, respectively, when all sources were considered. Model results suggest that the heterogeneous reaction and the surface photolysis reaction are the most important sources of nitrous acid in the atmosphere, accounting for about 86% of the predicted nitrous acid. Emissions and the gas-phase reactions were relatively minor sources and accounted for only 14% of the predicted nitrous acid. Model predictions suggest that the heterogeneous reaction is the most significant source of nitrous acid at night, while the surface photolysis reaction is the most significant source during the day. The addition of these sources increased the diurnally averaged hydroxyl radicals and ozone by 10% and 1.4ppbv, respectively. JF - Atmospheric Environment AU - Sarwar, G AU - Roselle, S J AU - Mathur, R AU - Appel, W AU - Dennis, R L AU - Vogel, B AD - US Environmental Protection Agency, RTP, NC 27711, USA, sarwar.golam@epa.gov Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 5760 EP - 5770 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 23 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Photolysis KW - Atmospheric pollution models KW - Air quality KW - Particulates KW - Atmosphere KW - Hydroxyl radicals KW - Air quality models KW - Emissions KW - Emission measurements KW - Oxidants KW - Ozone KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19472297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=A+comparison+of+CMAQ+HONO+predictions+with+observations+from+the+Northeast+Oxidant+and+Particle+Study&rft.au=Sarwar%2C+G%3BRoselle%2C+S+J%3BMathur%2C+R%3BAppel%2C+W%3BDennis%2C+R+L%3BVogel%2C+B&rft.aulast=Sarwar&rft.aufirst=G&rft.date=2008-07-01&rft.volume=42&rft.issue=23&rft.spage=5760&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.12.065 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Photolysis; Atmospheric pollution models; Air quality models; Emission measurements; Emissions; Air quality; Particulates; Atmosphere; Oxidants; Ozone; Hydroxyl radicals DO - http://dx.doi.org/10.1016/j.atmosenv.2007.12.065 ER - TY - JOUR T1 - Incorporating Classification Uncertainty in Competing-Risks Nest-Failure Analysis AN - 19342317; 8699198 AB - There are many causes of nest failure in birds. Although partitioning the risk of nest failure among causes has long been of interest to ornithologists, application of formal methods for estimating competing risks has received little attention in the literature. We describe how evidence collected at nests can be formally incorporated into likelihood functions for competing risks to control classification uncertainty. We briefly review estimators for an idealized case in which all fates are known with certainty, and then we introduce new estimators for four cases in which evidence is used. In the evidence-based models, we consider several distinct types of evidence, including videographic evidence, static ecological evidence, and ecological evidence that decays over time. For each of the four cases using evidence, we compare the asymptotic sampling variance to the ideal case in which fates are always known. We also develop closed-form expressions for expected bias when assumptions underlying the estimators are not met. In all cases, use of evidence results in larger sampling variances for the failure probabilities than when fates are known with certainty. Typically, the magnitude of increase in sampling variance depends on the inverse of the evidence probabilities. We also show that disjoint evidence does not reduce sampling variance and should be ignored. Finally, we show that violations of underlying assumptions cause bias, though the bias may be tolerable in some cases. JF - Auk AU - Etterson, Matthew A AU - Stanley, Thomas R AD - 1U.S. Environmental Protection Agency, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804, USA; and Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 687 EP - 699 PB - University of California Press, 2000 Center St, Ste 303 VL - 125 IS - 3 SN - 0004-8038, 0004-8038 KW - Ecology Abstracts; Animal Behavior Abstracts KW - classification uncertainty KW - competing risks KW - Mayfield Markov chain KW - nest survival KW - nest videography KW - Classification KW - Survival KW - Sampling KW - Decay KW - Nests KW - Models KW - Y 25150:General/Miscellaneous KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19342317?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Auk&rft.atitle=Incorporating+Classification+Uncertainty+in+Competing-Risks+Nest-Failure+Analysis&rft.au=Etterson%2C+Matthew+A%3BStanley%2C+Thomas+R&rft.aulast=Etterson&rft.aufirst=Matthew&rft.date=2008-07-01&rft.volume=125&rft.issue=3&rft.spage=687&rft.isbn=&rft.btitle=&rft.title=Auk&rft.issn=00048038&rft_id=info:doi/10.1525%2Fauk.2008.07045 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Classification; Survival; Decay; Sampling; Nests; Models DO - http://dx.doi.org/10.1525/auk.2008.07045 ER - TY - JOUR T1 - Comparative Pharmacokinetics of Perfluorobutyrate in Rats, Mice, Monkeys, and Humans and Relevance to Human Exposure via Drinking Water AN - 19309362; 8305259 AB - Perfluorobutyrate (PFBA) has been detected in precipitation, surface waters, water treatment effluent, and in public and private wells in Minnesota at up to low mu g/l concentrations. We evaluated the pharmacokinetics of PFBA in rats, mice, monkeys, and humans to provide a rational basis for dose selection in toxicological studies and to aid in human-health-risk assessment. Studies included (1) rats-iv and oral; (2) mice-oral; (3) monkeys-iv; and (4) humans-occupationally exposed volunteers. PFBA was determined in serum (all species), liver (rats and mice), urine (rats, mice, and monkeys), and feces (rats and mice). In addition, we characterized serum PFBA concentrations in 177 individuals with potential exposure to PFBA through drinking water. Mean terminal serum PFBA elimination half-lives for males (M) and females (F), respectively, in h were (1) for rats given 30 mg/kg, 9.22 and 1.76 (oral), and 6.38 and 1.03 (iv); (2) for mice given oral doses of 10, 30, or 100 mg/kg ammonium PFBA, 13.34 and 2.87 at 10 mg/kg, 16.25 and 3.08 at 30 mg/kg; and 5.22 and 2.79 at 100 mg/kg; (3) for monkeys given 10 mg/kg iv, 40.32 and 41.04; and (4) for humans, 72.16 and 87.00 (74.63 combined). Volume of distribution estimates indicated primarily extracellular distribution. Among individuals with plausible exposure via drinking water, 96% of serum PFBA concentrations were < 2 ng/ml (maximum 6 ng/ml). These findings demonstrate that PFBA is eliminated efficiently from serum with a low potential for accumulation from repeated exposure. JF - Toxicological Sciences AU - Chang, Shu-Ching AU - Das, Kaberi AU - Ehresman, David J AU - Ellefson, Mark E AU - Gorman, Gregory S AU - Hart, Jill A AU - Noker, Patricia E AU - Tan, Yu-Mei AU - Lieder, Paul H AU - Lau, Christopher AU - Olsen, Geary W AU - Butenhoff, John L AD - Medical Department, 3M Company, St Paul, Minnesota 55144. United States Environmental Protection Agency, Reproductive Toxicology Division, Research Triangle Park, North Carolina 27711. Environmental Laboratory, 3M Company, St Paul, Minnesota 55144. Southern Research Institute, Birmingham, Alabama 35205. The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 Y1 - 2008/07// PY - 2008 DA - Jul 2008 SP - 40 EP - 53 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 104 IS - 1 SN - 1096-6080, 1096-6080 KW - Water Resources Abstracts; Toxicology Abstracts KW - Ammonium KW - Surface water KW - Mice KW - Surface Water KW - Precipitation KW - Effluents KW - USA, Minnesota KW - Pharmacokinetics KW - Drinking Water KW - Public Health KW - Assessments KW - Water treatment KW - Urine KW - Exposure KW - Liver KW - Drinking water KW - Feces KW - SW 3030:Effects of pollution KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19309362?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Comparative+Pharmacokinetics+of+Perfluorobutyrate+in+Rats%2C+Mice%2C+Monkeys%2C+and+Humans+and+Relevance+to+Human+Exposure+via+Drinking+Water&rft.au=Chang%2C+Shu-Ching%3BDas%2C+Kaberi%3BEhresman%2C+David+J%3BEllefson%2C+Mark+E%3BGorman%2C+Gregory+S%3BHart%2C+Jill+A%3BNoker%2C+Patricia+E%3BTan%2C+Yu-Mei%3BLieder%2C+Paul+H%3BLau%2C+Christopher%3BOlsen%2C+Geary+W%3BButenhoff%2C+John+L&rft.aulast=Chang&rft.aufirst=Shu-Ching&rft.date=2008-07-01&rft.volume=104&rft.issue=1&rft.spage=40&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Ammonium; Water treatment; Surface water; Urine; Liver; Precipitation; Feces; Effluents; Drinking water; Pharmacokinetics; Public Health; Drinking Water; Assessments; Exposure; Mice; Surface Water; USA, Minnesota ER - TY - CPAPER T1 - Observations - EPA's Assistance of Partners in Protecting the Chesapeake Bay T2 - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AN - 41051905; 4908688 JF - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AU - Fuller, Linda AU - Engelberg, Dan Y1 - 2008/06/30/ PY - 2008 DA - 2008 Jun 30 KW - USA, Chesapeake Bay KW - Shore protection UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41051905?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.atitle=Observations+-+EPA%27s+Assistance+of+Partners+in+Protecting+the+Chesapeake+Bay&rft.au=Fuller%2C+Linda%3BEngelberg%2C+Dan&rft.aulast=Fuller&rft.aufirst=Linda&rft.date=2008-06-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/Virginia_Beach2008/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dynamic River Networks as the Context for Evaluating Riparian Influence on River Basin Solute Export T2 - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AN - 41050170; 4908671 JF - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AU - Wigington, Parker Y1 - 2008/06/30/ PY - 2008 DA - 2008 Jun 30 KW - Exports KW - River basins KW - Solutes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41050170?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.atitle=Dynamic+River+Networks+as+the+Context+for+Evaluating+Riparian+Influence+on+River+Basin+Solute+Export&rft.au=Wigington%2C+Parker&rft.aulast=Wigington&rft.aufirst=Parker&rft.date=2008-06-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/Virginia_Beach2008/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Impacts on Floodplains by an Invasive Shrub, Buddleja davidii T2 - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AN - 41048377; 4908724 JF - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AU - Tallent-Halsell, Nita AU - Walker, Lawrence R Y1 - 2008/06/30/ PY - 2008 DA - 2008 Jun 30 KW - Shrubs KW - Flood plains KW - Buddleja davidii UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41048377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.atitle=Impacts+on+Floodplains+by+an+Invasive+Shrub%2C+Buddleja+davidii&rft.au=Tallent-Halsell%2C+Nita%3BWalker%2C+Lawrence+R&rft.aulast=Tallent-Halsell&rft.aufirst=Nita&rft.date=2008-06-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/Virginia_Beach2008/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Riparian and Watershed Land Cover at Multiple Landscape Scales for Great River Sampling Sites within the Mississippi Basin T2 - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AN - 41047036; 4908654 JF - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AU - Moffett, Mary F AU - Bolgrien, David W AU - Nawrocki, Tatiana AU - Starry, Matthew A AU - Angradi, Theodore R AU - Hill, Brian H AU - Jicha, Terri M AU - Pearson, Mark S AU - Taylor, Debra L Y1 - 2008/06/30/ PY - 2008 DA - 2008 Jun 30 KW - USA, Indiana, Great R. KW - USA, Mississippi KW - Watersheds KW - Basins KW - Landscape KW - Sampling KW - Rivers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41047036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.atitle=Riparian+and+Watershed+Land+Cover+at+Multiple+Landscape+Scales+for+Great+River+Sampling+Sites+within+the+Mississippi+Basin&rft.au=Moffett%2C+Mary+F%3BBolgrien%2C+David+W%3BNawrocki%2C+Tatiana%3BStarry%2C+Matthew+A%3BAngradi%2C+Theodore+R%3BHill%2C+Brian+H%3BJicha%2C+Terri+M%3BPearson%2C+Mark+S%3BTaylor%2C+Debra+L&rft.aulast=Moffett&rft.aufirst=Mary&rft.date=2008-06-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/Virginia_Beach2008/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Recovery of Nitrogen Pools and Processes in Degraded Riparian Zones in the Southern Appalachians T2 - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AN - 41045861; 4908607 JF - 2008 AWRA Summer Specialty Conference on Riparian Ecosystems and Buffers: Working at the Water's Edge AU - Walker, John AU - Vose, Jim AU - Knoepp, Jennifer AU - Geron, Christopher D Y1 - 2008/06/30/ PY - 2008 DA - 2008 Jun 30 KW - Nitrogen KW - Riparian zone UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41045861?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.atitle=Recovery+of+Nitrogen+Pools+and+Processes+in+Degraded+Riparian+Zones+in+the+Southern+Appalachians&rft.au=Walker%2C+John%3BVose%2C+Jim%3BKnoepp%2C+Jennifer%3BGeron%2C+Christopher+D&rft.aulast=Walker&rft.aufirst=John&rft.date=2008-06-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+AWRA+Summer+Specialty+Conference+on+Riparian+Ecosystems+and+Buffers%3A+Working+at+the+Water%27s+Edge&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/Virginia_Beach2008/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Corporate Green Power Purchasing T2 - 2008 Annual Meeting and Food Expo of the Institute of Food Technologists AN - 41041640; 4894981 JF - 2008 Annual Meeting and Food Expo of the Institute of Food Technologists AU - Clouse, M Y1 - 2008/06/28/ PY - 2008 DA - 2008 Jun 28 KW - Purchasing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41041640?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Annual+Meeting+and+Food+Expo+of+the+Institute+of+Food+Technologists&rft.atitle=Corporate+Green+Power+Purchasing&rft.au=Clouse%2C+M&rft.aulast=Clouse&rft.aufirst=M&rft.date=2008-06-28&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Meeting+and+Food+Expo+of+the+Institute+of+Food+Technologists&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={7416B4B4 -7931-416A-B8E9-D7C271C3FE8C}&AKey={8616C01D-DC03-41AD-9244-6706B0A8 C9BD} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Fate and transport of emissions for several trace metals over the United States. AN - 69184399; 18394683 AB - A regional model for atmospheric photochemistry and particulate matter is used to predict the fate and transport of five trace metals: lead, manganese, total chromium, nickel, and cadmium over the continental United States during January and July 2001. Predicted concentrations of the metals are compared to observations. Lead predictions have the lowest mean differences with observations and the highest correlation coefficients. They best agree with observations made in January over residential and commercial areas in the eastern United States and worst with observations over remote forests and deserts located in the western United States during July. Manganese predictions show similar abilities to reproduce observations but had larger changes between months. Chromium and nickel predictions show diminishing ability to reproduce observations over both urban and rural areas. Cadmium predictions show the least ability to reproduce observations. Potential causes are examined for the errors in predictions. For errors in lead, manganese and perhaps chromium predictions, aerial suspension and biomass burning are suspected because simulations did not include emissions from these sources. Nickel, cadmium and, to a lower extent, chromium predictions suffer from errors in the emissions that represent current anthropogenic activities. Predicted concentrations of all metals show errors from not including sub-grid processes in meteorological and emission rates. Examples include sea breeze circulation along coastal areas and individual sources in urban areas. These errors reduce the ability to reproduce the time dependence of observations. JF - The Science of the total environment AU - Hutzell, William T AU - Luecken, Deborah J AD - Atmospheric Modeling Division, National Exposure Research Laboratory, US Environmental, Protection Agency, Research Triangle Park, North Carolina 27711, USA. hutzell.bill@epa.gov Y1 - 2008/06/25/ PY - 2008 DA - 2008 Jun 25 SP - 164 EP - 179 VL - 396 IS - 2-3 SN - 0048-9697, 0048-9697 KW - Air Pollutants KW - 0 KW - Metals, Heavy KW - Particulate Matter KW - Index Medicus KW - United States KW - Environmental Monitoring KW - Forecasting KW - Air Pollutants -- analysis KW - Particulate Matter -- analysis KW - Models, Theoretical KW - Metals, Heavy -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69184399?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Fate+and+transport+of+emissions+for+several+trace+metals+over+the+United+States.&rft.au=Hutzell%2C+William+T%3BLuecken%2C+Deborah+J&rft.aulast=Hutzell&rft.aufirst=William&rft.date=2008-06-25&rft.volume=396&rft.issue=2-3&rft.spage=164&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2008.02.020 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-10 N1 - Date created - 2008-05-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.scitotenv.2008.02.020 ER - TY - CPAPER T1 - The Influence of Roadway Configuration on Near-Road Air Quality T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41044815; 4907960 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Baldauf, R AU - Bowker, G AU - Heist, D AU - Perry, S AU - Thoma, E AU - Long, T AU - Hagler, G AU - Khlystov, A AU - Brixey, L Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Air quality KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41044815?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=The+Influence+of+Roadway+Configuration+on+Near-Road+Air+Quality&rft.au=Baldauf%2C+R%3BBowker%2C+G%3BHeist%2C+D%3BPerry%2C+S%3BThoma%2C+E%3BLong%2C+T%3BHagler%2C+G%3BKhlystov%2C+A%3BBrixey%2C+L&rft.aulast=Baldauf&rft.aufirst=R&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Spatially- and Temporally-Resolved Measurement of Roadway Air Pollution Using a Zero-Emissions Electric Vehicle T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41041526; 4908023 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Hagler, G AU - Thoma, E AU - Mitchell, W AU - Thompson, E AU - Kinsey, J AU - Baldauf, R Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Air pollution KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41041526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=Spatially-+and+Temporally-Resolved+Measurement+of+Roadway+Air+Pollution+Using+a+Zero-Emissions+Electric+Vehicle&rft.au=Hagler%2C+G%3BThoma%2C+E%3BMitchell%2C+W%3BThompson%2C+E%3BKinsey%2C+J%3BBaldauf%2C+R&rft.aulast=Hagler&rft.aufirst=G&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of EPA OTM 10 for Landfill Applications, Interim Report T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41041370; 4907942 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Thoma, E AU - Thorneloe, S AU - Green, R AU - Hater, G AU - Hashmonay, R AU - Chase, M AU - Modrak, M AU - Goldsmith, D Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Landfills KW - Waste disposal sites KW - EPA KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41041370?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=Development+of+EPA+OTM+10+for+Landfill+Applications%2C+Interim+Report&rft.au=Thoma%2C+E%3BThorneloe%2C+S%3BGreen%2C+R%3BHater%2C+G%3BHashmonay%2C+R%3BChase%2C+M%3BModrak%2C+M%3BGoldsmith%2C+D&rft.aulast=Thoma&rft.aufirst=E&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Aspects Related to Controlling and Quantifying Cr and Cr(6) T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41041360; 4907753 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Serageldin, M Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Emission control KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41041360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=Aspects+Related+to+Controlling+and+Quantifying+Cr+and+Cr%286%29&rft.au=Serageldin%2C+M&rft.aulast=Serageldin&rft.aufirst=M&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Impact of Meteorology, Traffic Characteristics, and Distance from Roadway on Roadside Concentrations of Ultrafine Particulate Matter T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41041062; 4907836 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Hagler, G AU - Thoma, E AU - Long, T AU - Baldauf, R AU - Snow, R Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Particulate matter KW - Roadsides KW - Traffic KW - Meteorology KW - Suspended particulate matter KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41041062?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=Impact+of+Meteorology%2C+Traffic+Characteristics%2C+and+Distance+from+Roadway+on+Roadside+Concentrations+of+Ultrafine+Particulate+Matter&rft.au=Hagler%2C+G%3BThoma%2C+E%3BLong%2C+T%3BBaldauf%2C+R%3BSnow%2C+R&rft.aulast=Hagler&rft.aufirst=G&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Forensic Link Between Ambient Air Monitoring Filters and Radiation Detection Analysis to Benefit Homeland Security T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41039280; 4907651 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Musick, D Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Filters KW - Security KW - Radiation KW - Forensic science KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41039280?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=The+Forensic+Link+Between+Ambient+Air+Monitoring+Filters+and+Radiation+Detection+Analysis+to+Benefit+Homeland+Security&rft.au=Musick%2C+D&rft.aulast=Musick&rft.aufirst=D&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling Approaches for Characterizing Pollutant Concentrations Near Roads T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41035655; 4907959 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Cook, R AU - Bailey, C AU - Baldauf, R Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Pollutants KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41035655?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=Modeling+Approaches+for+Characterizing+Pollutant+Concentrations+Near+Roads&rft.au=Cook%2C+R%3BBailey%2C+C%3BBaldauf%2C+R&rft.aulast=Cook&rft.aufirst=R&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - AERMOD Sensitivity to the Choice of Surface Characteristics T2 - 101st Annual Conference and Exhibition of the Air and Waste Management Association AN - 41034404; 4907636 JF - 101st Annual Conference and Exhibition of the Air and Waste Management Association AU - Brode, R AU - Wesson, K AU - Thurman, J AU - Tillerson, C Y1 - 2008/06/24/ PY - 2008 DA - 2008 Jun 24 KW - Models KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41034404?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.atitle=AERMOD+Sensitivity+to+the+Choice+of+Surface+Characteristics&rft.au=Brode%2C+R%3BWesson%2C+K%3BThurman%2C+J%3BTillerson%2C+C&rft.aulast=Brode&rft.aufirst=R&rft.date=2008-06-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=101st+Annual+Conference+and+Exhibition+of+the+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractonline.com/viewer/browseOptions.asp?MKey={EDF17668- D85D-4ADF-BB4B-795DC0621B8B}&AKey={B2B3355E-B6DC-4154-ABE7-63E874668 9A8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Comparison of estrogen-responsive plasma protein biomarkers and reproductive endpoints in sheepshead minnows exposed to 17 beta -trenbolone AN - 19301299; 8259316 AB - Protein profiling can be used for detection of biomarkers that can be applied diagnostically to screen chemicals for endocrine modifying activity. In previous studies, mass spectral analysis revealed four peptides (2950.5, 2972.5, 3003.4, 3025.5m/z) in the plasma of estrogen agonist-treated male and gravid female sheepshead minnows (Cyprinodon variegatus, SHM), which served as distinct estrogenic biomarkers. In this study, a 21-day reproductive assay with adult SHM was conducted to investigate possible dose-related effects of the synthetic androgen, 17 beta -trenbolone, on expression of these four estrogen-responsive peptides. In addition, the response of the peptide biomarkers were compared to traditional reproductive endpoints of fecundity, histopathology, secondary sex characteristics, length, weight, hepatosomatic index, female gonadosomatic index and plasma vitellogenin (VTG) levels. Fish were continuously exposed to 0.005, 0.05, and 5.0 mu g/l, a solvent control (triethylene glycol, TEG), and a seawater control (SW) using an intermittent flow-through dosing system. Plasma was analyzed for the presence of the four peptide biomarkers by MALDI-TOF MS and VTG protein by quantitative ELISA. Male fish from the trenbolone treatments and controls showed no expression of the four peptide biomarkers or measurable levels of VTG. The estrogen-responsive biomarkers and plasma VTG were constitutively expressed in females from the SW, TEG, 0.005 and 0.05 mu g/l exposures. All four peptide biomarkers were significantly reduced (p<0.0002 to p<0.005) at the 5.0 mu g/l treatment level which corresponded with significant reductions in fecundity and changes in ovarian morphology. A distinct but non-significant reduction in VTG was also observed in female fish from the 5.0 mu g/l treatment. Results of this study suggest application of these estrogen-responsive protein biomarkers may be a cost effective alternative to fecundity measures which are labor intensive and expensive to conduct. JF - Aquatic Toxicology AU - Hemmer, MJ AU - Cripe, G M AU - Hemmer, B L AU - Goodman, L R AU - Salinas, KA AU - Fournie, J W AU - Walker, C C AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, FL 32561, USA, hemmer.michael@epa.gov Y1 - 2008/06/23/ PY - 2008 DA - 2008 Jun 23 SP - 128 EP - 136 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 88 IS - 2 SN - 0166-445X, 0166-445X KW - Sheepshead minnow KW - Aqualine Abstracts; Pollution Abstracts; Toxicology Abstracts; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - trenbolone KW - Histopathology KW - Secondary sexual characters KW - Biomarkers KW - Freshwater KW - Freshwater fish KW - Sex hormones KW - Weight KW - Marine environment KW - Assay KW - triethylene glycol KW - Bioindicators KW - Enzyme-linked immunosorbent assay KW - Sexual Reproduction KW - Fecundity KW - Fish physiology KW - Peptides KW - Fish KW - Cyprinodon variegatus KW - estrogens KW - Chemicals KW - Spectral Analysis KW - Seawater KW - fecundity KW - Plasma proteins KW - Gonadosomatic index KW - Estrogens KW - Solvents KW - biomarkers KW - Vitellogenin KW - Morphology KW - Proteins KW - Reproduction KW - Androgens KW - X 24310:Pharmaceuticals KW - P 1000:MARINE POLLUTION KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - Q1 08344:Reproduction and development KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19301299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Toxicology&rft.atitle=Comparison+of+estrogen-responsive+plasma+protein+biomarkers+and+reproductive+endpoints+in+sheepshead+minnows+exposed+to+17+beta+-trenbolone&rft.au=Hemmer%2C+MJ%3BCripe%2C+G+M%3BHemmer%2C+B+L%3BGoodman%2C+L+R%3BSalinas%2C+KA%3BFournie%2C+J+W%3BWalker%2C+C+C&rft.aulast=Hemmer&rft.aufirst=MJ&rft.date=2008-06-23&rft.volume=88&rft.issue=2&rft.spage=128&rft.isbn=&rft.btitle=&rft.title=Aquatic+Toxicology&rft.issn=0166445X&rft_id=info:doi/10.1016%2Fj.aquatox.2008.04.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Gonadosomatic index; Fecundity; Fish physiology; Secondary sexual characters; Histopathology; Reproduction; Biomarkers; Freshwater fish; Sex hormones; Plasma proteins; trenbolone; Enzyme-linked immunosorbent assay; Estrogens; Marine environment; Vitellogenin; Solvents; triethylene glycol; biomarkers; Androgens; Chemicals; fecundity; Bioindicators; Seawater; Morphology; Proteins; estrogens; Weight; Spectral Analysis; Assay; Fish; Peptides; Sexual Reproduction; Cyprinodon variegatus; Freshwater DO - http://dx.doi.org/10.1016/j.aquatox.2008.04.001 ER - TY - JOUR T1 - Environmental mass spectrometry: emerging contaminants and current issues. AN - 71670209; 18498180 JF - Analytical chemistry AU - Richardson, Susan D AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, Athens, Georgia 30605, USA. Y1 - 2008/06/15/ PY - 2008 DA - 2008 Jun 15 SP - 4373 EP - 4402 VL - 80 IS - 12 KW - Environmental Pollutants KW - 0 KW - Pharmaceutical Preparations KW - Water KW - 059QF0KO0R KW - Index Medicus KW - Water -- analysis KW - Animals KW - Humans KW - Nanostructures -- analysis KW - Pharmaceutical Preparations -- analysis KW - Environment KW - Mass Spectrometry -- methods KW - Environmental Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71670209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Environmental+mass+spectrometry%3A+emerging+contaminants+and+current+issues.&rft.au=Richardson%2C+Susan+D&rft.aulast=Richardson&rft.aufirst=Susan&rft.date=2008-06-15&rft.volume=80&rft.issue=12&rft.spage=4373&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=1520-6882&rft_id=info:doi/10.1021%2Fac800660d LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-08 N1 - Date created - 2008-06-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1021/ac800660d ER - TY - JOUR T1 - Occurrence of contaminant accumulation in lead pipe scales from domestic drinking-water distribution systems. AN - 69294873; 18613340 AB - Previously, contaminants, such as AI, As, and Ra, have been shown to accumulate in drinking-water distribution system solids. Accumulated contaminants could be periodically released back into the water supply causing elevated levels at consumers taps, going undetected by most current regulatory monitoring practices and consequently constituting a hidden risk. The objective of this study was to determine the occurrence of over 40 major scale constituents, regulated metals, and other potential metallic inorganic contaminants in drinking-water distribution system Pb (lead) or Pb-lined service lines. The primary method of analysis was inductively coupled plasma-atomic emission spectroscopy, following complete decomposition of scale material. Contaminants and scale constituents were categorized by their average concentrations, and many metals of potential health concern were found to occur at levels sufficient to result in elevated levels at the consumer's taps if they were to be mobilized. The data indicate distinctly nonconservative behavior for many inorganic contaminants in drinking-water distribution systems. This finding suggests an imminent need for further research into the transport and fate of contaminants throughout drinking-water distribution system pipes, as well as a re-evaluation of monitoring protocols in order to more accurately determine the scope and levels of potential consumer exposure. JF - Environmental science & technology AU - Schock, Michael R AU - Hyland, Robert N AU - Welch, Meghan M AD - United States Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Water Supply and Water Resources Division, Cincinnati, Ohio 45268, USA. schock.michael@epa.gov Y1 - 2008/06/15/ PY - 2008 DA - 2008 Jun 15 SP - 4285 EP - 4291 VL - 42 IS - 12 SN - 0013-936X, 0013-936X KW - Water Pollutants, Chemical KW - 0 KW - Lead KW - 2P299V784P KW - Index Medicus KW - Water Pollutants, Chemical -- analysis KW - Water Supply KW - Lead -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69294873?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Occurrence+of+contaminant+accumulation+in+lead+pipe+scales+from+domestic+drinking-water+distribution+systems.&rft.au=Schock%2C+Michael+R%3BHyland%2C+Robert+N%3BWelch%2C+Meghan+M&rft.aulast=Schock&rft.aufirst=Michael&rft.date=2008-06-15&rft.volume=42&rft.issue=12&rft.spage=4285&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-10 N1 - Date created - 2008-07-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Modulation of pulmonary inflammatory responses and antimicrobial defenses in mice exposed to diesel exhaust AN - 19705714; 8259044 AB - Diesel exhaust (DE) is a major component of urban air pollution and has been shown to increase the severity of infectious and allergic lung disease. The purpose of this study was to evaluate the effects of DE exposure on pulmonary inflammation, mediator production and antimicrobial defenses in an exposure model that had previously been shown to increase susceptibility to influenza. BALB/c mice were exposed to filtered air, or to DE diluted to yield 0.5 or 2 mg /m super(3) of diesel exhaust particles (DEP) for 4 h per day for 1 or 5 days. Immediately and 18 h after one or five diesel exposures mice were euthanized to assess both immediate and delayed effects. DE exposure for 5 days at either concentration caused higher neutrophil numbers and lesion scoring compared to air controls. Intracellular adhesion molecule-1 (ICAM-1), which recruits inflammatory cells and is an entry site for rhinoviruses was increased immediately after 1 or 5 days of DE exposure. Several inflammatory and immune cytokines (TNF-a, MIP-2, IL-6, IFN-g, and IL-13) were also upregulated at various time points and concentrations. In contrast, clara cell secretory protein (CCSP), surfactant protein A (SP-A), and surfactant protein D (SP-D) which are important host defense molecules, were significantly decreased at both the message and protein level with DE exposure. We conclude that exposure to moderate and high occupational levels of DE caused an increase in lung injury and inflammation, and a decrease in host defense molecules, which could result in increased susceptibility to respiratory pathogens. JF - Toxicology and Applied Pharmacology AU - Gowdy, K AU - Krantz, Q T AU - Daniels, M AU - Linak, W P AU - Jaspers, I AU - Gilmour, MI AD - National Health and Environmental Effects Research Laboratory, United States Environmental Protection Agency, RTP, NC 27711, USA, gilmour.ian@epa.gov Y1 - 2008/06/15/ PY - 2008 DA - 2008 Jun 15 SP - 310 EP - 319 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 229 IS - 3 SN - 0041-008X, 0041-008X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts; Health & Safety Science Abstracts; Pollution Abstracts; Toxicology Abstracts KW - Interleukin 6 KW - Injuries KW - Animal models KW - surfactant protein D KW - Particulates KW - influenza KW - Influenza KW - Interleukin 13 KW - surfactant protein A KW - intercellular adhesion molecule 1 KW - Lesions KW - Rhinovirus KW - Occupational exposure KW - Exhaust emissions KW - Urban areas KW - g-Interferon KW - Lung diseases KW - Leukocytes (neutrophilic) KW - Mice KW - Pathogens KW - Tumor necrosis factor-a KW - Clara cell secretory protein KW - Exhausts KW - Inflammation KW - Air pollution KW - Lung KW - Proteins KW - adhesion KW - Diesel KW - Surfactants KW - Diesel engines KW - antimicrobial agents KW - A 01340:Antibiotics & Antimicrobials KW - V 22410:Animal Diseases KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19705714?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Modulation+of+pulmonary+inflammatory+responses+and+antimicrobial+defenses+in+mice+exposed+to+diesel+exhaust&rft.au=Gowdy%2C+K%3BKrantz%2C+Q+T%3BDaniels%2C+M%3BLinak%2C+W+P%3BJaspers%2C+I%3BGilmour%2C+MI&rft.aulast=Gowdy&rft.aufirst=K&rft.date=2008-06-15&rft.volume=229&rft.issue=3&rft.spage=310&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2008.01.040 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Interleukin 6; g-Interferon; Injuries; Leukocytes (neutrophilic); Lung diseases; Animal models; surfactant protein D; Pathogens; Tumor necrosis factor-a; Inflammation; Exhausts; Clara cell secretory protein; Influenza; Air pollution; Interleukin 13; surfactant protein A; intercellular adhesion molecule 1; Diesel; Occupational exposure; Mice; Particulates; influenza; Lung; Proteins; Lesions; adhesion; Diesel engines; Surfactants; antimicrobial agents; Urban areas; Exhaust emissions; Rhinovirus DO - http://dx.doi.org/10.1016/j.taap.2008.01.040 ER - TY - CPAPER T1 - Loss of Virus-specific Memory T Cells in Coxsackievirus B3 and B4-infected Mice T2 - 2008 Federation of Clinical Immunology Societies Conference (FOCIS 2008) AN - 41052283; 4911251 JF - 2008 Federation of Clinical Immunology Societies Conference (FOCIS 2008) AU - Li, Lu AU - Dufour, Alfred Y1 - 2008/06/05/ PY - 2008 DA - 2008 Jun 05 KW - Mice KW - Memory cells KW - Lymphocytes T KW - Immunological memory KW - Coxsackievirus B3 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41052283?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Federation+of+Clinical+Immunology+Societies+Conference+%28FOCIS+2008%29&rft.atitle=Loss+of+Virus-specific+Memory+T+Cells+in+Coxsackievirus+B3+and+B4-infected+Mice&rft.au=Li%2C+Lu%3BDufour%2C+Alfred&rft.aulast=Li&rft.aufirst=Lu&rft.date=2008-06-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Federation+of+Clinical+Immunology+Societies+Conference+%28FOCIS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.focisnet.org/meetings/am08/FOCIS_2008_Program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Relationship of plasma sex steroid concentrations in female fathead minnows to reproductive success and population status AN - 19300499; 8257743 AB - Concentration and/or production of sex steroids such as 17 beta -estradiol (E2) and testosterone (T) in fish have commonly been measured in field studies concerned with endocrine-active chemicals. There is a reasonable mechanistic basis for using E2 or T as biomarkers, as chemicals can alter steroid production through both direct and indirect effects on the hypothalamic-pituitary-gonadal (HPG) axis. There is uncertainty, however, as to what changes in steroid status may mean relative to apical endpoints, such as reproduction, that directly affect population status. In this study, we analyzed data from fathead minnow (Pimephales promelas) reproduction studies in which decreases in fecundity were associated with depressed steroid production as a result of chemical exposure. Although the chemicals acted on the HPG axis through different mechanisms, reproductive effects appeared to be expressed through a common pathway, depression of vitellogenin production in females. Plasma concentrations of E2 or T in the females were significantly, positively correlated with fecundity. Linear regression models describing the relationship between E2 or T concentrations and relative fecundity were linked to a population model to predict population trajectories of fathead minnows exposed to chemicals that inhibit steroid production. For example, a population existing at carrying capacity and exposed to a chemical stressor(s) that causes a 50% decrease in E2 production was predicted to exhibit a 92% decrease in population size over a 5-year period. Results of our analysis illustrate a conceptual framework whereby a commonly measured biomarker, sex steroid status, could be linked to individual- and population-level effects in fish. JF - Aquatic Toxicology AU - Ankley, G T AU - Miller, D H AU - Jensen, K M AU - Villeneuve, D L AU - Martinovic, D AD - Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, MN 55804 USA, ankley.gerald@epa.gov Y1 - 2008/06/02/ PY - 2008 DA - 2008 Jun 02 SP - 69 EP - 74 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 88 IS - 1 SN - 0166-445X, 0166-445X KW - Fathead minnow KW - Aqualine Abstracts; Pollution Abstracts; Toxicology Abstracts; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Biomarkers KW - Freshwater KW - Freshwater fish KW - Sex hormones KW - Hypothalamic-pituitary-gonadal axis KW - Exposure KW - Populations KW - Bioindicators KW - Depression KW - Fathead Minnows KW - depression KW - Sexual Reproduction KW - carrying capacity KW - Model Studies KW - Testosterone KW - Fecundity KW - Water Pollution Effects KW - Fish KW - Chemicals KW - Pollution effects KW - steroids KW - Models KW - fecundity KW - Carrying Capacity KW - Regression analysis KW - 17 beta -Estradiol KW - Steroids KW - Data processing KW - Carrying capacity KW - Steroid hormones KW - biomarkers KW - Pimephales promelas KW - Vitellogenin KW - Population status KW - Reproduction KW - Females KW - population status KW - Breeding success KW - X 24310:Pharmaceuticals KW - P 2000:FRESHWATER POLLUTION KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - Q1 08344:Reproduction and development KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19300499?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Toxicology&rft.atitle=Relationship+of+plasma+sex+steroid+concentrations+in+female+fathead+minnows+to+reproductive+success+and+population+status&rft.au=Ankley%2C+G+T%3BMiller%2C+D+H%3BJensen%2C+K+M%3BVilleneuve%2C+D+L%3BMartinovic%2C+D&rft.aulast=Ankley&rft.aufirst=G&rft.date=2008-06-02&rft.volume=88&rft.issue=1&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Aquatic+Toxicology&rft.issn=0166445X&rft_id=info:doi/10.1016%2Fj.aquatox.2008.03.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Fecundity; Pollution effects; Females; Biomarkers; Freshwater fish; Steroids; Breeding success; Sex hormones; Depression; Data processing; Carrying capacity; Steroid hormones; biomarkers; Models; Hypothalamic-pituitary-gonadal axis; Testosterone; Vitellogenin; Population status; Regression analysis; 17 beta -Estradiol; Reproduction; Bioindicators; fecundity; Chemicals; steroids; depression; carrying capacity; population status; Carrying Capacity; Exposure; Water Pollution Effects; Fish; Fathead Minnows; Populations; Sexual Reproduction; Model Studies; Pimephales promelas; Freshwater DO - http://dx.doi.org/10.1016/j.aquatox.2008.03.005 ER - TY - JOUR T1 - Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants. AN - 70768301; 18433959 AB - Physiologically-based pharmacokinetic (PBPK) models are being developed to evaluate whether humans in early life are more or less susceptible to adverse effects than adults from exposure to chemicals because of reduced renal clearance. To support the development of such models, data on the rates of glomerular filtration, tubular secretion, tubular reabsorption, and renal blood flow in neonates and infants were compiled and summarized. All three processes are deficient in the newborn with varying maturation rates during the first months and years of life. Glomerular filtration rate (GFR) has traditionally been the primary indicator of kidney function, and in full-term neonates (<1-month-old) is about 30% of the adult level, subsequently approaching adult rates between 6 months and 1 year of age. Tubular secretion is around 25% of adult levels at birth, and increases more slowly and more variably than GFR, not approaching adult levels until 1-5 years of age. Limited data on renal plasma flow indicate neonatal rates of only 10-20% of adult values that rapidly increase to 50% by 6 months, and then approach adult levels by 1-2 years of age. Examples of PBPK model representations of renal clearance for chemicals that are primarily cleared by the kidneys are discussed in terms of their use in evaluating early life stage susceptibility. JF - Regulatory toxicology and pharmacology : RTP AU - DeWoskin, Robert S AU - Thompson, Chad M AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Mail Drop B243-01, Research Triangle Park, NC 27711, USA. dewoskin.rob@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 66 EP - 86 VL - 51 IS - 1 SN - 0273-2300, 0273-2300 KW - Environmental Pollutants KW - 0 KW - Xenobiotics KW - Index Medicus KW - Rats KW - Infant KW - Kidney Function Tests KW - Animals, Newborn KW - Animals KW - Humans KW - Adult KW - Infant, Newborn KW - Metabolic Clearance Rate KW - Child KW - Adolescent KW - Child, Preschool KW - Xenobiotics -- pharmacokinetics KW - Kidney -- metabolism KW - Models, Biological KW - Environmental Pollutants -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70768301?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.atitle=Renal+clearance+parameters+for+PBPK+model+analysis+of+early+lifestage+differences+in+the+disposition+of+environmental+toxicants.&rft.au=DeWoskin%2C+Robert+S%3BThompson%2C+Chad+M&rft.aulast=DeWoskin&rft.aufirst=Robert&rft.date=2008-06-01&rft.volume=51&rft.issue=1&rft.spage=66&rft.isbn=&rft.btitle=&rft.title=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.issn=02732300&rft_id=info:doi/10.1016%2Fj.yrtph.2008.02.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-31 N1 - Date created - 2008-05-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.yrtph.2008.02.005 ER - TY - JOUR T1 - Maternal exposure to water disinfection by-products during gestation and risk of hypospadias. AN - 70765672; 18032532 AB - The use of chlorine for water disinfection results in the formation of numerous contaminants called disinfection by-products (DBPs), which may be associated with birth defects, including urinary tract defects. We used Arkansas birth records (1998-2002) to conduct a population-based case-control study investigating the relationship between hypospadias and two classes of DBPs, trihalomethanes (THM) and haloacetic acids (HAA). We utilised monitoring data, spline regression and geographical information systems (GIS) to link daily concentrations of these DBPs from 263 water utilities to 320 cases and 614 controls. We calculated ORs for hypospadias and exposure to DBPs between 6 and 16 weeks' gestation, and conducted subset analyses for exposure from ingestion, and metrics incorporating consumption, showering and bathing. We found no increase in risk when women in the highest tertiles of exposure were compared to those in the lowest for any DBP. When ingestion alone was used to assess exposure among a subset of 40 cases and 243 controls, the intermediate tertiles of exposure to total THM and the five most common HAA had ORs of 2.11 (95% CI 0.89 to 5.00) and 2.45 (95% CI 1.06 to 5.67), respectively, compared to women with no exposure. When exposure to total THM from consumption, showering and bathing exposures was evaluated, we found an OR of 1.96 (95% CI 0.65 to 6.42) for the highest tertile of exposure and weak evidence of a dose-response relationship. Our results provide little evidence for a positive relationship between DBP exposure during gestation and an increased risk of hypospadias but emphasise the necessity of including individual-level data when assessing exposure to DBPs. JF - Occupational and environmental medicine AU - Luben, T J AU - Nuckols, J R AU - Mosley, B S AU - Hobbs, C AU - Reif, J S AD - National Center for Environmental Assessment, Office of Research and Development, US Environmental Protection Agency, MC B-243-01, Research Triangle Park, North Carolina 27711, USA. luben.tom@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 420 EP - 429 VL - 65 IS - 6 KW - Fluoroacetates KW - 0 KW - Trihalomethanes KW - Water Pollutants, Chemical KW - Chlorine KW - 4R7X1O2820 KW - Index Medicus KW - Disinfection KW - Humans KW - Environmental Exposure -- analysis KW - Infant, Newborn KW - Arkansas -- epidemiology KW - Fluoroacetates -- analysis KW - Trihalomethanes -- analysis KW - Pregnancy KW - Maternal-Fetal Exchange KW - Water Supply -- analysis KW - Fluoroacetates -- toxicity KW - Case-Control Studies KW - Trihalomethanes -- toxicity KW - Epidemiological Monitoring KW - Environmental Exposure -- adverse effects KW - Chlorine -- chemistry KW - Male KW - Environmental Monitoring -- methods KW - Female KW - Hypospadias -- chemically induced KW - Water Pollutants, Chemical -- analysis KW - Water Pollutants, Chemical -- toxicity KW - Prenatal Exposure Delayed Effects -- chemically induced KW - Water Purification KW - Hypospadias -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70765672?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+and+environmental+medicine&rft.atitle=Maternal+exposure+to+water+disinfection+by-products+during+gestation+and+risk+of+hypospadias.&rft.au=Luben%2C+T+J%3BNuckols%2C+J+R%3BMosley%2C+B+S%3BHobbs%2C+C%3BReif%2C+J+S&rft.aulast=Luben&rft.aufirst=T&rft.date=2008-06-01&rft.volume=65&rft.issue=6&rft.spage=420&rft.isbn=&rft.btitle=&rft.title=Occupational+and+environmental+medicine&rft.issn=1470-7926&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-04 N1 - Date created - 2008-05-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Carbon monoxide reversibly alters iron homeostasis and respiratory epithelial cell function. AN - 70742489; 18203974 AB - The dissociation of iron from heme is a major factor in iron metabolism and the cellular concentrations of the metal correlate with heme degradation. We tested the hypotheses that (1) exposure to a product of heme catabolism, carbon monoxide (CO), alters iron homeostasis in the lung and in cultured respiratory epithelial cells; (2) this response includes both decreased uptake and increased release of cell metal; and (3) the effects of CO on cell function track changes in metal homeostasis. In rats exposed to 50 ppm CO for 24 hours, non-heme iron concentrations decreased in the lung and increased in the liver. In respiratory epithelial cells cultured at air-liquid interface, CO exposure decreased cell non-heme iron and ferritin concentrations within 2 hours and the effect was fully reversible. CO significantly depressed iron uptake by epithelial cells, despite increased expression of divalent metal transporter-1, while iron release was elevated. The loss of non-heme iron after CO reduced cellular oxidative stress, blocked the release of the proinflammatory mediator (interleukin-8), and interfered with cell cycle protein expression. We conclude that CO reduces the iron content of the lung through both the metal uptake and release mechanisms. This loss of cellular iron after CO is in line with certain biological effects of the gas that have been implicated in the protection of cell viability. JF - American journal of respiratory cell and molecular biology AU - Ghio, Andrew J AU - Stonehuerner, Jacqueline G AU - Dailey, Lisa A AU - Richards, Judy H AU - Madden, Michael D AU - Deng, Zhongping AU - Nguyen, N-B AU - Callaghan, Kimberly D AU - Yang, Funmei AU - Piantadosi, Claude A AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, United States Environmental Protection Agency, Research Triangle Park, North Carolina, USA. ghio.andy@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 715 EP - 723 VL - 38 IS - 6 KW - Antimetabolites KW - 0 KW - Antioxidants KW - Interleukin-8 KW - Siderophores KW - Heme KW - 42VZT0U6YR KW - Carbon Monoxide KW - 7U1EE4V452 KW - Ferritins KW - 9007-73-2 KW - Iron KW - E1UOL152H7 KW - Acetaldehyde KW - GO1N1ZPR3B KW - Deferoxamine KW - J06Y7MXW4D KW - Index Medicus KW - Animals KW - Siderophores -- metabolism KW - Humans KW - Bronchoalveolar Lavage KW - Acetaldehyde -- metabolism KW - Child KW - Cell Proliferation KW - Deferoxamine -- metabolism KW - Rats KW - Rats, Sprague-Dawley KW - Antioxidants -- metabolism KW - Ferritins -- metabolism KW - Heme -- chemistry KW - Oxidative Stress KW - Interleukin-8 -- metabolism KW - Heme -- metabolism KW - Male KW - Cell Line KW - Epithelial Cells -- metabolism KW - Carbon Monoxide -- pharmacology KW - Antimetabolites -- pharmacology KW - Epithelial Cells -- cytology KW - Epithelial Cells -- drug effects KW - Antimetabolites -- metabolism KW - Respiratory Mucosa -- cytology KW - Respiratory Mucosa -- drug effects KW - Homeostasis KW - Carbon Monoxide -- metabolism KW - Iron -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70742489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+respiratory+cell+and+molecular+biology&rft.atitle=Carbon+monoxide+reversibly+alters+iron+homeostasis+and+respiratory+epithelial+cell+function.&rft.au=Ghio%2C+Andrew+J%3BStonehuerner%2C+Jacqueline+G%3BDailey%2C+Lisa+A%3BRichards%2C+Judy+H%3BMadden%2C+Michael+D%3BDeng%2C+Zhongping%3BNguyen%2C+N-B%3BCallaghan%2C+Kimberly+D%3BYang%2C+Funmei%3BPiantadosi%2C+Claude+A&rft.aulast=Ghio&rft.aufirst=Andrew&rft.date=2008-06-01&rft.volume=38&rft.issue=6&rft.spage=715&rft.isbn=&rft.btitle=&rft.title=American+journal+of+respiratory+cell+and+molecular+biology&rft.issn=1535-4989&rft_id=info:doi/10.1165%2Frcmb.2007-0179OC LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-19 N1 - Date created - 2008-05-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1165/rcmb.2007-0179OC ER - TY - JOUR T1 - Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid. AN - 69419293; 18467677 AB - Health concerns have been raised because perfluorooctanoic acid (PFOA) is commonly found in the environment and can be detected in humans. In rodents, PFOA is a carcinogen and a developmental toxicant. PFOA is a peroxisome proliferator-activated receptor alpha (PPARalpha) activator; however, PFOA is capable of inducing heptomegaly in the PPARalpha-null mouse. To study the mechanism associated with PFOA toxicity, wild-type and PPARalpha-null mice were orally dosed for 7 days with PFOA (1 or 3 mg/kg) or the PPARalpha agonist Wy14,643 (50 mg/kg). Gene expression was evaluated using commercial microarrays. In wild-type mice, PFOA and Wy14,643 induced changes consistent with activation of PPARalpha. PFOA-treated wild-type mice deviated from Wy14,643-exposed mice with respect to genes involved in xenobiotic metabolism. In PFOA-treated null mice, changes were observed in transcripts related to fatty acid metabolism, inflammation, xenobiotic metabolism, and cell cycle regulation. Hence, a component of the PFOA response was found to be independent of PPARalpha. Although the signaling pathways responsible for these effects are not readily apparent, overlapping gene regulation by additional PPAR isoforms could account for changes related to fatty acid metabolism and inflammation, whereas regulation of xenobiotic metabolizing genes is suggestive of constitutive androstane receptor activation. JF - Toxicologic pathology AU - Rosen, Mitchell B AU - Abbott, Barbara D AU - Wolf, Douglas C AU - Corton, J Christopher AU - Wood, Carmen R AU - Schmid, Judith E AU - Das, Kaberi P AU - Zehr, Robert D AU - Blair, Eric T AU - Lau, Christopher AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Reproductive Toxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. rosen.mitch@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 592 EP - 607 VL - 36 IS - 4 KW - Caprylates KW - 0 KW - Environmental Pollutants KW - Fluorocarbons KW - PPAR alpha KW - Pyrimidines KW - pirinixic acid KW - 86C4MRT55A KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Animals KW - Oligonucleotide Array Sequence Analysis KW - Pyrimidines -- toxicity KW - Mice KW - Reverse Transcriptase Polymerase Chain Reaction KW - Male KW - Mice, Knockout KW - Gene Expression -- drug effects KW - Gene Expression Profiling KW - Fluorocarbons -- pharmacokinetics KW - Liver -- pathology KW - Environmental Pollutants -- toxicity KW - Liver -- drug effects KW - Fluorocarbons -- toxicity KW - Liver -- metabolism KW - Caprylates -- toxicity KW - PPAR alpha -- metabolism KW - Caprylates -- pharmacokinetics KW - PPAR alpha -- genetics KW - Environmental Pollutants -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69419293?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+pathology&rft.atitle=Gene+profiling+in+the+livers+of+wild-type+and+PPARalpha-null+mice+exposed+to+perfluorooctanoic+acid.&rft.au=Rosen%2C+Mitchell+B%3BAbbott%2C+Barbara+D%3BWolf%2C+Douglas+C%3BCorton%2C+J+Christopher%3BWood%2C+Carmen+R%3BSchmid%2C+Judith+E%3BDas%2C+Kaberi+P%3BZehr%2C+Robert+D%3BBlair%2C+Eric+T%3BLau%2C+Christopher&rft.aulast=Rosen&rft.aufirst=Mitchell&rft.date=2008-06-01&rft.volume=36&rft.issue=4&rft.spage=592&rft.isbn=&rft.btitle=&rft.title=Toxicologic+pathology&rft.issn=1533-1601&rft_id=info:doi/10.1177%2F0192623308318208 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-20 N1 - Date created - 2008-08-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1177/0192623308318208 ER - TY - JOUR T1 - Comparative hepatic effects of perfluorooctanoic acid and WY 14,643 in PPAR-alpha knockout and wild-type mice. AN - 69419269; 18467680 AB - Perfluorooctanoic acid (PFOA) is a chemical used in the production of fluoropolymers. Its persistence in the environment and presence in humans and wildlife has raised health concerns. Liver tumor induction by PFOA is thought to be mediated in rodents by PPAR-alpha. A recent US EPA scientific advisory board questioned the contribution of PPAR-alpha in PFOA-induced liver tumors. Liver response in CD-1, SV/129 wild-type (WT), and PPAR-alpha knockout (KO) SV/129 mice was evaluated after seven daily treatments of PFOA-NH4(+) (1, 3, or 10 mg/kg, p.o.) or the prototype PPARalpha-agonist Wyeth 14,643 (WY, 50 mg/kg). Livers were examined by light and electron microscopy. Proliferation was quantified after PCNA immunostaining. PFOA treatment induced a dose-dependent increase in hepatocyte hypertrophy and labeling index (LI) similar to WY in WT mice. Ultrastructural alterations of peroxisome proliferation were similar between WY-treated and 10 mg/kg PFOA-treated WT mice. KO mice had a dose-dependent increase in hepatocyte vacuolation but increased LI only at 10 mg PFOA/kg. WY-treated KO mice were not different from KO control. These data suggest that PPAR-alpha is required for WY- and PFOA-induced cellular alterations in WT mouse liver. Hepatic enlargement observed in KO mice may be due to an accumulation of cytoplasmic vacuoles that contain PFOA. JF - Toxicologic pathology AU - Wolf, Douglas C AU - Moore, Tanya AU - Abbott, Barbara D AU - Rosen, Mitchell B AU - Das, Kaberi P AU - Zehr, Robert D AU - Lindstrom, Andrew B AU - Strynar, Mark J AU - Lau, Christopher AD - Environmental Carcinogenesis Division, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. wolf.doug@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 632 EP - 639 VL - 36 IS - 4 KW - Caprylates KW - 0 KW - Environmental Pollutants KW - Fluorocarbons KW - PPAR alpha KW - Pyrimidines KW - pirinixic acid KW - 86C4MRT55A KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Cell Proliferation -- drug effects KW - Animals KW - Hepatocytes -- drug effects KW - Hepatocytes -- ultrastructure KW - Dose-Response Relationship, Drug KW - Mice KW - Organ Size -- drug effects KW - Mice, Knockout KW - Hepatocytes -- metabolism KW - Fluorocarbons -- pharmacokinetics KW - Environmental Pollutants -- toxicity KW - Fluorocarbons -- toxicity KW - Caprylates -- toxicity KW - Liver -- metabolism KW - Pyrimidines -- blood KW - Pyrimidines -- pharmacokinetics KW - PPAR alpha -- agonists KW - PPAR alpha -- genetics KW - Environmental Pollutants -- pharmacokinetics KW - Liver -- ultrastructure KW - Caprylates -- blood KW - Liver -- drug effects KW - Pyrimidines -- toxicity KW - Fluorocarbons -- blood KW - PPAR alpha -- physiology KW - Caprylates -- pharmacokinetics KW - Environmental Pollutants -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69419269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+pathology&rft.atitle=Comparative+hepatic+effects+of+perfluorooctanoic+acid+and+WY+14%2C643+in+PPAR-alpha+knockout+and+wild-type+mice.&rft.au=Wolf%2C+Douglas+C%3BMoore%2C+Tanya%3BAbbott%2C+Barbara+D%3BRosen%2C+Mitchell+B%3BDas%2C+Kaberi+P%3BZehr%2C+Robert+D%3BLindstrom%2C+Andrew+B%3BStrynar%2C+Mark+J%3BLau%2C+Christopher&rft.aulast=Wolf&rft.aufirst=Douglas&rft.date=2008-06-01&rft.volume=36&rft.issue=4&rft.spage=632&rft.isbn=&rft.btitle=&rft.title=Toxicologic+pathology&rft.issn=1533-1601&rft_id=info:doi/10.1177%2F0192623308318216 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-20 N1 - Date created - 2008-08-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1177/0192623308318216 ER - TY - JOUR T1 - An approach for evaluating the effectiveness of various ozone air quality standards for protecting trees. AN - 69395156; 18157645 AB - We demonstrate an approach for evaluating the level of protection attained using a variety of forms and levels of past, current, and proposed Air Quality Standards (AQSs). The U.S. Clean Air Act requires the establishment of ambient air quality standards to protect health and public welfare. However, determination of attainment of these standards is based on ambient pollutant concentrations rather than prevention of adverse effects. To determine if a given AQS protected against adverse effects on vegetation, hourly ozone concentrations were adjusted to create exposure levels that "just attain" a given standard. These exposures were used in combination with a physiologically-based tree growth model to account for the interactions of climate and ozone. In the evaluation, we used ozone concentrations from two 6-year time periods from the San Bernardino Mountains in California. There were clear differences in the level of vegetation protection achieved with the various AQSs. Based on modeled plant growth, the most effective standards were the California 8-hr average maximum of 70 ppb and a seasonal, cumulative, concentration-weighted index (SUM06), which if attained, resulted in annual growth reductions of 1% or less. Least effective was the 1-hr maximum of 120 ppb which resulted in a 7% annual reduction. We conclude that combining climate, exposure scenarios, and a process-based plant growth simulator was a useful approach for evaluating effectiveness of current or proposed air quality standards, or evaluating the form and/or level of a standard based on preventing adverse growth effects. JF - Environmental management AU - Hogsett, William E AU - Tingey, David T AU - Lee, E Henry AU - Beedlow, Peter A AU - Andersen, Christian P AD - U.S. EPA, Office of Research and Development, National Environmental and Health Effects Laboratory, Western Ecology Division, Corvallis, Oregon 97333, USA. hogsett.william@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 937 EP - 948 VL - 41 IS - 6 SN - 0364-152X, 0364-152X KW - Air Pollutants KW - 0 KW - Ozone KW - 66H7ZZK23N KW - Index Medicus KW - Computer Simulation KW - Air Pollution -- prevention & control KW - Population Dynamics KW - Humans KW - Climate KW - Models, Biological KW - Ozone -- analysis KW - Pinus ponderosa -- metabolism KW - Ozone -- poisoning KW - Air -- standards KW - Air Pollutants -- analysis KW - Pinus ponderosa -- growth & development KW - Air -- analysis KW - Air Pollutants -- poisoning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69395156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+management&rft.atitle=An+approach+for+evaluating+the+effectiveness+of+various+ozone+air+quality+standards+for+protecting+trees.&rft.au=Hogsett%2C+William+E%3BTingey%2C+David+T%3BLee%2C+E+Henry%3BBeedlow%2C+Peter+A%3BAndersen%2C+Christian+P&rft.aulast=Hogsett&rft.aufirst=William&rft.date=2008-06-01&rft.volume=41&rft.issue=6&rft.spage=937&rft.isbn=&rft.btitle=&rft.title=Environmental+management&rft.issn=0364152X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-22 N1 - Date created - 2008-08-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Investigating compensation and recovery of fathead minnow (Pimephales promelas) exposed to 17alpha-ethynylestradiol with metabolite profiling. AN - 69276055; 18589986 AB - 1H NMR spectroscopy was used to profile metabolite changes in the livers of fathead minnows (Pimephales promelas) exposed to the synthetic estrogen 17alpha-ethynylestradiol (EE2) via a continuous flow water exposure. Fish were exposed to either 10 or 100 ng EE2/L for 8 days, followed by an 8 day depuration phase. Livers were collected after days 1, 4, and 8 of the exposure, and at the end of the depuration phase. Analysis of polar extracts of the liver revealed a greater impact of EE2 on males than females, with metabolite profiles of the former assuming similarities with those of the females (i.e., feminization) early in the exposure. Biochemical effects observed in the males included changes in metabolites relating to energetics (e.g., glycogen, glucose, and lactate) and liver toxicity (creatine and bile acids). In addition, amino acids associated with vitellogenin (VTG) synthesis increased in livers of EE2-exposed males, a finding consistent with increased plasma concentrations of the lipoprotein in the fish. Using partial least-squares discriminant analysis (PLS-DA), the response trajectories of the males at both exposure concentrations were compared. This revealed an apparent ability of the fish to compensate for the presence of EE2 later in the exposure, and to partially recover from its effects after the chemical was removed. JF - Environmental science & technology AU - Ekman, D R AU - Teng, Q AU - Villeneuve, D L AU - Kahl, M D AU - Jensen, K M AU - Durhan, E J AU - Ankley, G T AU - Collette, T W AD - Ecosystems Research Division, U.S. EPA, 960 College Station Road, Athens, Georgia 30605, USA. ekman.drew@epa.gov Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 SP - 4188 EP - 4194 VL - 42 IS - 11 SN - 0013-936X, 0013-936X KW - Estrogens KW - 0 KW - Vitellogenins KW - Lactic Acid KW - 33X04XA5AT KW - Glutamic Acid KW - 3KX376GY7L KW - Betaine KW - 3SCV180C9W KW - Ethinyl Estradiol KW - 423D2T571U KW - Glycogen KW - 9005-79-2 KW - Glucose KW - IY9XDZ35W2 KW - Alanine KW - OF5P57N2ZX KW - Index Medicus KW - Animals KW - Vitellogenins -- blood KW - Glutamic Acid -- metabolism KW - Glycogen -- metabolism KW - Betaine -- metabolism KW - Alanine -- metabolism KW - Glucose -- metabolism KW - Male KW - Lactic Acid -- metabolism KW - Female KW - Liver -- drug effects KW - Cyprinidae -- physiology KW - Liver -- metabolism KW - Ethinyl Estradiol -- toxicity KW - Feminization -- chemically induced KW - Estrogens -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69276055?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Investigating+compensation+and+recovery+of+fathead+minnow+%28Pimephales+promelas%29+exposed+to+17alpha-ethynylestradiol+with+metabolite+profiling.&rft.au=Ekman%2C+D+R%3BTeng%2C+Q%3BVilleneuve%2C+D+L%3BKahl%2C+M+D%3BJensen%2C+K+M%3BDurhan%2C+E+J%3BAnkley%2C+G+T%3BCollette%2C+T+W&rft.aulast=Ekman&rft.aufirst=D&rft.date=2008-06-01&rft.volume=42&rft.issue=11&rft.spage=4188&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-31 N1 - Date created - 2008-07-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A synthesis of climate-change effects on aquatic invasive species. Introduction. AN - 69256174; 18577080 JF - Conservation biology : the journal of the Society for Conservation Biology AU - Bierwagen, Britta G AU - Rahel, Frank J AU - Thomas, Roxanne AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW, Washington, D.C. 20460, USA. bierwagen.britta@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 518 EP - 520 VL - 22 IS - 3 KW - Water KW - 059QF0KO0R KW - Index Medicus KW - Environmental Monitoring KW - Demography KW - Public Policy KW - Ecosystem KW - Plants -- metabolism KW - Greenhouse Effect KW - Climate KW - Conservation of Natural Resources UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69256174?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Conservation+biology+%3A+the+journal+of+the+Society+for+Conservation+Biology&rft.atitle=A+synthesis+of+climate-change+effects+on+aquatic+invasive+species.+Introduction.&rft.au=Bierwagen%2C+Britta+G%3BRahel%2C+Frank+J%3BThomas%2C+Roxanne&rft.aulast=Bierwagen&rft.aufirst=Britta&rft.date=2008-06-01&rft.volume=22&rft.issue=3&rft.spage=518&rft.isbn=&rft.btitle=&rft.title=Conservation+biology+%3A+the+journal+of+the+Society+for+Conservation+Biology&rft.issn=1523-1739&rft_id=info:doi/10.1111%2Fj.1523-1739.2008.00958.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-27 N1 - Date created - 2008-06-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1523-1739.2008.00958.x ER - TY - JOUR T1 - Integrated monitoring and information systems for managing aquatic invasive species in a changing climate. AN - 69255779; 18577087 AB - Changes in temperature, precipitation, and other climatic drivers and sea-level rise will affect populations of existing native and non-native aquatic species and the vulnerability of aquatic environments to new invasions. Monitoring surveys provide the foundation for assessing the combined effects of climate change and invasions by providing baseline biotic and environmental conditions, although the utility of a survey depends on whether the results are quantitative or qualitative, and other design considerations. The results from a variety of monitoring programs in the United States are available in integrated biological information systems, although many include only non-native species, not native species. Besides including natives, we suggest these systems could be improved through the development of standardized methods that capture habitat and physiological requirements and link regional and national biological databases into distributed Web portals that allow drawing information from multiple sources. Combining the outputs from these biological information systems with environmental data would allow the development of ecological-niche models that predict the potential distribution or abundance of native and non-native species on the basis of current environmental conditions. Environmental projections from climate models can be used in these niche models to project changes in species distributions or abundances under altered climatic conditions and to identify potential high-risk invaders. There are, however, a number of challenges, such as uncertainties associated with projections from climate and niche models and difficulty in integrating data with different temporal and spatial granularity. Even with these uncertainties, integration of biological and environmental information systems, niche models, and climate projections would improve management of aquatic ecosystems under the dual threats of biotic invasions and climate change. JF - Conservation biology : the journal of the Society for Conservation Biology AU - Lee, Henry AU - Reusser, Deborah A AU - Olden, Julian D AU - Smith, Scott S AU - Graham, Jim AU - Burkett, Virginia AU - Dukes, Jeffrey S AU - Piorkowski, Robert J AU - McPhedran, John AD - Western Ecology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, 2111 SE Marine Science Drive, Newport, OR 97365, USA. lee.henry@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 575 EP - 584 VL - 22 IS - 3 KW - Water KW - 059QF0KO0R KW - Index Medicus KW - Demography KW - Greenhouse Effect KW - Conservation of Natural Resources -- methods KW - Models, Biological KW - Ecosystem KW - Databases, Factual -- standards KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69255779?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Conservation+biology+%3A+the+journal+of+the+Society+for+Conservation+Biology&rft.atitle=Integrated+monitoring+and+information+systems+for+managing+aquatic+invasive+species+in+a+changing+climate.&rft.au=Lee%2C+Henry%3BReusser%2C+Deborah+A%3BOlden%2C+Julian+D%3BSmith%2C+Scott+S%3BGraham%2C+Jim%3BBurkett%2C+Virginia%3BDukes%2C+Jeffrey+S%3BPiorkowski%2C+Robert+J%3BMcPhedran%2C+John&rft.aulast=Lee&rft.aufirst=Henry&rft.date=2008-06-01&rft.volume=22&rft.issue=3&rft.spage=575&rft.isbn=&rft.btitle=&rft.title=Conservation+biology+%3A+the+journal+of+the+Society+for+Conservation+Biology&rft.issn=1523-1739&rft_id=info:doi/10.1111%2Fj.1523-1739.2008.00955.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-27 N1 - Date created - 2008-06-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1523-1739.2008.00955.x ER - TY - JOUR T1 - Capacity of management plans for aquatic invasive species to integrate climate change. AN - 69254265; 18577086 AB - The consequences of climate change will affect aquatic ecosystems, including aquatic invasive species (AIS) that are already affecting these ecosystems. Effects on AIS include range shifts and more frequent overwintering of species. These effects may create new challenges for AIS management. We examined available U.S. state AIS management plans to assess each program's capacity to adapt to climate-change effects. We scored the adaptive capacity of AIS management plans on the basis of whether they addressed potential impacts resulting from climate change; demonstrated a capacity to adapt to changing conditions; provided for monitoring strategies; provided for plan revisions; and described funding for implementation. Most plans did not mention climate change specifically, but some did acknowledge climatic boundaries of species and ecosystem sensitivities to changing conditions. Just under half the plans mentioned changing environmental conditions as a factor, most frequently as part of research activities. Activities associated with monitoring showed the highest capacity to include information on changing conditions, and future revisions to management plans are likely to be the easiest avenue through which to address climate-change effects on AIS management activities. Our results show that programs have the capacity to incorporate information about climate-change effects and that the adaptive-management framework may be an appropriate approach. JF - Conservation biology : the journal of the Society for Conservation Biology AU - Bierwagen, Britta G AU - Thomas, Roxanne AU - Kane, Austin AD - Global Change Research Program, National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue NW, Washington, D.C. 20460, USA. bierwagen.britta@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 568 EP - 574 VL - 22 IS - 3 KW - Water KW - 059QF0KO0R KW - Index Medicus KW - United States KW - Animals KW - Ecosystem KW - Greenhouse Effect KW - Environmental Monitoring -- standards KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69254265?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Conservation+biology+%3A+the+journal+of+the+Society+for+Conservation+Biology&rft.atitle=Capacity+of+management+plans+for+aquatic+invasive+species+to+integrate+climate+change.&rft.au=Bierwagen%2C+Britta+G%3BThomas%2C+Roxanne%3BKane%2C+Austin&rft.aulast=Bierwagen&rft.aufirst=Britta&rft.date=2008-06-01&rft.volume=22&rft.issue=3&rft.spage=568&rft.isbn=&rft.btitle=&rft.title=Conservation+biology+%3A+the+journal+of+the+Society+for+Conservation+Biology&rft.issn=1523-1739&rft_id=info:doi/10.1111%2Fj.1523-1739.2008.00954.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-27 N1 - Date created - 2008-06-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1523-1739.2008.00954.x ER - TY - JOUR T1 - Alternative test methods in inhalation toxicology: challenges and opportunities. AN - 69207868; 18486462 AB - Requirements under the new European Union rules regarding Registration, Evaluation & Authorization of Chemicals (REACH) necessitate widespread toxicological safety testing of existing and new chemicals. Given the enormity of new and already in-service chemicals that fall under this new rule, obtaining inhalation toxicity testing data has unique challenges when compared to most biotesting regimes due to the complexity, time and expense involved in conducting standardized inhalation assessments of whole animals. A number of in vitro approaches have been used to obtain respiratory system-related information, but there is no universal or accepted test system to replace inhalation exposure studies. There are many considerations that must be satisfied before adopting any single in vitro bioassay or battery of such assays to substitute for whole animal inhalation data. These considerations relate mostly to the relevance of the bioassay(s) regarding selection of bioassay cell type(s), dose, and fundamental study procedures. There are data in the literature although these have not been well-assessed for such applications, and there exist perhaps more relevant unpublished data in the private sector that could provide guidance on this issue. The formation of a coalition of scientists to assess current knowledge and perhaps to consider a basic comparative study where consensus approaches (with frank discussions of their strengths and weaknesses) would be invaluable to the testing community and to the ultimate protection of human health. In May 2007, a Congress of government, industry, and academic scientists met at the Federal Institute for Risk Assessment (BfR), Berlin, on the subject of Alternative Test Methods in Inhalation Toxicology. The stimulus for the meeting arose from the European Union's (EU) recent implementation of the new REACH safety testing requirements for commercial chemicals and products. Attendees at the meeting presented a panoply of data and perspectives on the state of the science on alternative testing methods and how these might aid safety assessments of inhaled materials. The focus of many presentations was on the fundamental attributes of inhalation toxicology and how these are translated or otherwise addressed in alternative in vitro test methods. There was recognition of the needs and the potential for progress through collaboration, but there remains a clear need for continued discussion and proactive support to a broad-based comparative study. The present discussion provides one perspective of this complex issue and how the science community might collaborate to develop acceptable alternative approaches based in science that have utility in inhalation toxicological assessments. JF - Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie AU - Costa, Daniel L AD - Pulmonary Toxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. costa.dan@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 105 EP - 109 VL - 60 IS - 2-3 SN - 0940-2993, 0940-2993 KW - Xenobiotics KW - 0 KW - Index Medicus KW - Animals KW - Government Regulation KW - European Union KW - Consensus Development Conferences as Topic KW - Risk Assessment KW - Xenobiotics -- administration & dosage KW - Xenobiotics -- classification KW - Inhalation Exposure KW - Animal Testing Alternatives -- legislation & jurisprudence KW - Tissue Culture Techniques KW - Biological Assay KW - Animal Testing Alternatives -- methods KW - Toxicity Tests -- methods KW - Xenobiotics -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69207868?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Experimental+and+toxicologic+pathology+%3A+official+journal+of+the+Gesellschaft+fur+Toxikologische+Pathologie&rft.atitle=Alternative+test+methods+in+inhalation+toxicology%3A+challenges+and+opportunities.&rft.au=Costa%2C+Daniel+L&rft.aulast=Costa&rft.aufirst=Daniel&rft.date=2008-06-01&rft.volume=60&rft.issue=2-3&rft.spage=105&rft.isbn=&rft.btitle=&rft.title=Experimental+and+toxicologic+pathology+%3A+official+journal+of+the+Gesellschaft+fur+Toxikologische+Pathologie&rft.issn=09402993&rft_id=info:doi/10.1016%2Fj.etp.2008.01.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-17 N1 - Date created - 2008-06-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.etp.2008.01.001 ER - TY - CPAPER T1 - Detection of Mycobacterium avium subsp. paratuberculosis in Drinking Water and Biofilms Using Quantitative PCR T2 - 108th General Meeting of the American Society for Microbiology AN - 41003279; 4885652 JF - 108th General Meeting of the American Society for Microbiology AU - Beumer, A AU - King, D AU - Pfaller, S L Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Drinking water KW - Biofilms KW - Polymerase chain reaction KW - Paratuberculosis KW - Nucleotide sequence KW - Mycobacterium avium KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41003279?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Detection+of+Mycobacterium+avium+subsp.+paratuberculosis+in+Drinking+Water+and+Biofilms+Using+Quantitative+PCR&rft.au=Beumer%2C+A%3BKing%2C+D%3BPfaller%2C+S+L&rft.aulast=Beumer&rft.aufirst=A&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identifying Sources of Fecal Contamination in Streams Associated with Chicken Farms T2 - 108th General Meeting of the American Society for Microbiology AN - 41001017; 4885589 JF - 108th General Meeting of the American Society for Microbiology AU - Lee, Y AU - Molina, M AU - Willis, J AU - Domingo, J Santo AU - Lu, J. 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4885620 JF - 108th General Meeting of the American Society for Microbiology AU - Adcock, N J AU - Sivaganesan, M AU - Yu, A K AU - Brown, J D AU - Stallknecht, D E AU - Rice, E W Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Influenza KW - Viruses KW - Fowl plague KW - Phages KW - Bacteriophages KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40998110?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=The+Use+of+Bacteriophage+as+Surrogates+for+Avian+Influenza+Viruses+in+Persistence+Studies+in+Water&rft.au=Adcock%2C+N+J%3BSivaganesan%2C+M%3BYu%2C+A+K%3BBrown%2C+J+D%3BStallknecht%2C+D+E%3BRice%2C+E+W&rft.aulast=Adcock&rft.aufirst=N&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Interlaboratory Validation and Comparison of Methods for the Detection and Enumeration of Escherichia coli and Enterococci in Combined Sewer Overflows (CSO) T2 - 108th General Meeting of the American Society for Microbiology AN - 40997975; 4885602 JF - 108th General Meeting of the American Society for Microbiology AU - Oshiro, R K AU - Chambers, Y T AU - Chandler, K AU - Smith, M A Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Combined sewer overflows KW - Sewers KW - Overflow KW - Escherichia coli KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40997975?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Interlaboratory+Validation+and+Comparison+of+Methods+for+the+Detection+and+Enumeration+of+Escherichia+coli+and+Enterococci+in+Combined+Sewer+Overflows+%28CSO%29&rft.au=Oshiro%2C+R+K%3BChambers%2C+Y+T%3BChandler%2C+K%3BSmith%2C+M+A&rft.aulast=Oshiro&rft.aufirst=R&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Laboratory Evaluations of the Enterococcus qPCR Method for Recreational Water Quality Testing: Method Performance and Sources of Uncertainty in Quantitative Measurements T2 - 108th General Meeting of the American Society for Microbiology AN - 40996775; 4885089 JF - 108th General Meeting of the American Society for Microbiology AU - Haugland, R A AU - Siefring, S AU - Varma, M AU - Wymer, L Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Recreation areas KW - Water quality KW - Recreational waters KW - Enterococcus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40996775?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Laboratory+Evaluations+of+the+Enterococcus+qPCR+Method+for+Recreational+Water+Quality+Testing%3A+Method+Performance+and+Sources+of+Uncertainty+in+Quantitative+Measurements&rft.au=Haugland%2C+R+A%3BSiefring%2C+S%3BVarma%2C+M%3BWymer%2C+L&rft.aulast=Haugland&rft.aufirst=R&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Detection and Quantification of Human Fecal Pollution with Real-Time PCR T2 - 108th General Meeting of the American Society for Microbiology AN - 40994235; 4886065 JF - 108th General Meeting of the American Society for Microbiology AU - Shanks, O C AU - Kelty, C A AU - White, K AU - Sivaganesan, M AU - Domingo, J Santo AU - Varma, M AU - Haugland, R A Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Fecal coliforms KW - Polymerase chain reaction KW - Pollution KW - Pollution detection KW - Nucleotide sequence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40994235?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Detection+and+Quantification+of+Human+Fecal+Pollution+with+Real-Time+PCR&rft.au=Shanks%2C+O+C%3BKelty%2C+C+A%3BWhite%2C+K%3BSivaganesan%2C+M%3BDomingo%2C+J+Santo%3BVarma%2C+M%3BHaugland%2C+R+A&rft.aulast=Shanks&rft.aufirst=O&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Performance Assessment of Human-Specific PCR Microbial Source Tracking Assays T2 - 108th General Meeting of the American Society for Microbiology AN - 40993980; 4885076 JF - 108th General Meeting of the American Society for Microbiology AU - Kelty, C A AU - Blannon, J AU - White, K AU - Meckes, M AU - Shanks, O C Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Performance assessment KW - Polymerase chain reaction KW - Tracking KW - Nucleotide sequence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40993980?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Performance+Assessment+of+Human-Specific+PCR+Microbial+Source+Tracking+Assays&rft.au=Kelty%2C+C+A%3BBlannon%2C+J%3BWhite%2C+K%3BMeckes%2C+M%3BShanks%2C+O+C&rft.aulast=Kelty&rft.aufirst=C&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identification of Active Bacterial Communities in Drinking Water Using 16S rRNA-Based Sequence Analyses T2 - 108th General Meeting of the American Society for Microbiology AN - 40993090; 4884528 JF - 108th General Meeting of the American Society for Microbiology AU - Revetta, R P AU - Pemberton, A AU - Domingo, J. 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Santo Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Drinking water KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40993090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Identification+of+Active+Bacterial+Communities+in+Drinking+Water+Using+16S+rRNA-Based+Sequence+Analyses&rft.au=Revetta%2C+R+P%3BPemberton%2C+A%3BDomingo%2C+J.+W.+Santo&rft.aulast=Revetta&rft.aufirst=R&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Optimal Growth Conditions and Viability of Mycobacterium bovis (BCG) for the Performance Evaluation for Disinfectants with Tuberculocidal Claims T2 - 108th General Meeting of the American Society for Microbiology AN - 40991438; 4884650 JF - 108th General Meeting of the American Society for Microbiology AU - Hasan, J A AU - Duncan, M J AU - Tomasino, S F Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Growth conditions KW - Disinfectants KW - BCG KW - Growth KW - Mycobacterium bovis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40991438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Optimal+Growth+Conditions+and+Viability+of+Mycobacterium+bovis+%28BCG%29+for+the+Performance+Evaluation+for+Disinfectants+with+Tuberculocidal+Claims&rft.au=Hasan%2C+J+A%3BDuncan%2C+M+J%3BTomasino%2C+S+F&rft.aulast=Hasan&rft.aufirst=J&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of Enterococci and Bacteroidales Fecal Indicator Bacteria in a Lake Michigan Tributary by Real-Time Quantitative PCR T2 - 108th General Meeting of the American Society for Microbiology AN - 40991253; 4884628 JF - 108th General Meeting of the American Society for Microbiology AU - Chern, E C AU - Varma, M AU - Shively, D AU - Byappanahalli, M AU - Whitman, R AU - Zepp, R AU - Haugland, R Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - USA, Michigan L. KW - Fecal coliforms KW - Lakes KW - Polymerase chain reaction KW - Tributaries KW - Nucleotide sequence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40991253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Analysis+of+Enterococci+and+Bacteroidales+Fecal+Indicator+Bacteria+in+a+Lake+Michigan+Tributary+by+Real-Time+Quantitative+PCR&rft.au=Chern%2C+E+C%3BVarma%2C+M%3BShively%2C+D%3BByappanahalli%2C+M%3BWhitman%2C+R%3BZepp%2C+R%3BHaugland%2C+R&rft.aulast=Chern&rft.aufirst=E&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of 16S rDNA and Metagenomic Sequences Revealed Microbial Community and Host-Specific Sequences of Canadian Geese Feces T2 - 108th General Meeting of the American Society for Microbiology AN - 40991202; 4884525 JF - 108th General Meeting of the American Society for Microbiology AU - Lu, J. AU - Domingo, J. W. Santo AU - Edge, T AU - Hill, S Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Fecal coliforms KW - RRNA 16S KW - Feces KW - Aquatic birds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40991202?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Analysis+of+16S+rDNA+and+Metagenomic+Sequences+Revealed+Microbial+Community+and+Host-Specific+Sequences+of+Canadian+Geese+Feces&rft.au=Lu%2C+J.%3BDomingo%2C+J.+W.+Santo%3BEdge%2C+T%3BHill%2C+S&rft.aulast=Lu&rft.aufirst=J.&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A New Electropositive Filter for Concentrating Enterovirus, Adenovirus, and Norovirus from Large Volumes of Water T2 - 108th General Meeting of the American Society for Microbiology AN - 40987765; 4883173 JF - 108th General Meeting of the American Society for Microbiology AU - Karim, M R AU - Rhodes, E R AU - Brinkman, N AU - Wymer, L AU - Fout, G Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Filters KW - Adenovirus KW - Norovirus KW - Enterovirus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40987765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=A+New+Electropositive+Filter+for+Concentrating+Enterovirus%2C+Adenovirus%2C+and+Norovirus+from+Large+Volumes+of+Water&rft.au=Karim%2C+M+R%3BRhodes%2C+E+R%3BBrinkman%2C+N%3BWymer%2C+L%3BFout%2C+G&rft.aulast=Karim&rft.aufirst=M&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In Vitro Cell Culture and Real-Time Reverse-Transcriptase PCR-Based Assays to Detect Infective Toxoplasma gondii Oocysts T2 - 108th General Meeting of the American Society for Microbiology AN - 40986367; 4883197 JF - 108th General Meeting of the American Society for Microbiology AU - Augustine, S A J AU - Villegas, L F AU - Ware, M W AU - Hayes, S L AU - See, M J AU - Dubey, J P AU - Villegas, E N Y1 - 2008/06/01/ PY - 2008 DA - 2008 Jun 01 KW - Cell culture KW - Oocysts KW - Polymerase chain reaction KW - Nucleotide sequence KW - Toxoplasma gondii KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40986367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=In+Vitro+Cell+Culture+and+Real-Time+Reverse-Transcriptase+PCR-Based+Assays+to+Detect+Infective+Toxoplasma+gondii+Oocysts&rft.au=Augustine%2C+S+A+J%3BVillegas%2C+L+F%3BWare%2C+M+W%3BHayes%2C+S+L%3BSee%2C+M+J%3BDubey%2C+J+P%3BVillegas%2C+E+N&rft.aulast=Augustine&rft.aufirst=S+A&rft.date=2008-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=108th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/browseOptions.asp?MKey={47CAD92C -66A0-4310-9655-24A3F4FB5BD5}&AKey={32093528-52DC-4EBE-9D80-29DAD84C 92CE} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Nanotechnology and industrial ecology AN - 37119895; 3859187 JF - Journal of industrial ecology AU - Clift, Roland AU - Lloyd, Shannon AU - Karn, Barbara AU - Allenby, Braden R AU - Rejeski, Dave AU - Randles, Sally AU - Hunt, Geoffrey AU - Shatkin, Jo Anne AU - Seager, Thomas P AU - Linkov, Igor AU - MacCormack, Tyson J AU - Goss, Greg G AU - Reijnders, Lucas AU - Fiedeler, Ulrich AU - Eckelman, Matthew J AU - Zimmerman, Julie B AU - Anastas, Paul T AU - Sengül, Hatice AU - Theis, Thomas L AU - Ghosh, Siddhartha AU - Kushnir, Duncan AU - Sandén, Björn A AU - Healy, Meagan L AU - Dahlben, Lindsay J AU - Isaacs, Jacqueline A AU - Khanna, Vikas AU - Bakshi, Bhavik R AU - Lee, L James AU - Ok, Zeynep D AU - Benneyan, James C AU - Wardak, Ahson AU - Gorman, Michael E AU - Swami, Nathan AU - Deshpande, Shilpa AU - Helland, Aasgeir AU - Kastenholz, Hans AU - Siegrist, Michael AU - Smith, Sara E. Smiley AU - Hosgood, H Dean AU - Michelson, Evan S AU - Stowe, Meredith H AU - Joshi, Satish AD - University of Surrey ; US Environmental Protection Agency ; Arizona State University ; University of Manchester ; St Mary's University College ; University of Alberta ; University of Amsterdam ; Österreichische Akademie der Wissenschaften ; Yale University ; University of Illinois, Chicago ; Chalmers University of Technology ; Northeastern University ; Ohio State University ; University of Virginia ; Michigan State University Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 259 EP - 489 VL - 12 IS - 3 SN - 1088-1980, 1088-1980 KW - Economics KW - New technology KW - Production systems KW - Ecosystems KW - Energy utilization KW - Manufacturing KW - Regulation KW - Hazardous products KW - Systems analysis KW - Sustainability KW - Nanotechnology KW - Ecology KW - Industrial production KW - Decision making KW - Risk KW - Attitudes KW - Life cycles KW - Industrial management KW - Research methods KW - Environmental impact studies KW - Consumption KW - Pollution KW - Modelling UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37119895?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+industrial+ecology&rft.atitle=Nanotechnology+and+industrial+ecology&rft.au=Clift%2C+Roland%3BLloyd%2C+Shannon%3BKarn%2C+Barbara%3BAllenby%2C+Braden+R%3BRejeski%2C+Dave%3BRandles%2C+Sally%3BHunt%2C+Geoffrey%3BShatkin%2C+Jo+Anne%3BSeager%2C+Thomas+P%3BLinkov%2C+Igor%3BMacCormack%2C+Tyson+J%3BGoss%2C+Greg+G%3BReijnders%2C+Lucas%3BFiedeler%2C+Ulrich%3BEckelman%2C+Matthew+J%3BZimmerman%2C+Julie+B%3BAnastas%2C+Paul+T%3BSeng%C3%BCl%2C+Hatice%3BTheis%2C+Thomas+L%3BGhosh%2C+Siddhartha%3BKushnir%2C+Duncan%3BSand%C3%A9n%2C+Bj%C3%B6rn+A%3BHealy%2C+Meagan+L%3BDahlben%2C+Lindsay+J%3BIsaacs%2C+Jacqueline+A%3BKhanna%2C+Vikas%3BBakshi%2C+Bhavik+R%3BLee%2C+L+James%3BOk%2C+Zeynep+D%3BBenneyan%2C+James+C%3BWardak%2C+Ahson%3BGorman%2C+Michael+E%3BSwami%2C+Nathan%3BDeshpande%2C+Shilpa%3BHelland%2C+Aasgeir%3BKastenholz%2C+Hans%3BSiegrist%2C+Michael%3BSmith%2C+Sara+E.+Smiley%3BHosgood%2C+H+Dean%3BMichelson%2C+Evan+S%3BStowe%2C+Meredith+H%3BJoshi%2C+Satish&rft.aulast=Clift&rft.aufirst=Roland&rft.date=2008-06-01&rft.volume=12&rft.issue=3&rft.spage=259&rft.isbn=&rft.btitle=&rft.title=Journal+of+industrial+ecology&rft.issn=10881980&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Collection of 20 articles N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - Nanotechnology; 6397 10242 3872 554 971; 3858; 12474 971; 4325 3851 971; 12434; 4044 3858 8560 9511 4309; 8662 12622; 10277 10257 4722 12224 971; 7665 6431; 10742; 6383 7625; 11035; 10919; 7396 3245 971; 8162 8163; 3322 6071 1542 11325; 5750 10286; 9818; 4276 4249 2805 3872 554 971; 2805 3872 554 971; 1378 10404 ER - TY - JOUR T1 - The road to green nanotechnology AN - 37119343; 3858952 JF - Journal of industrial ecology AU - Karn, Barbara AD - US Environmental Protection Agency Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 263 EP - 266 VL - 12 IS - 3 SN - 1088-1980, 1088-1980 KW - Economics KW - Industrial production KW - New technology KW - Sustainability KW - Environmental protection KW - Nanotechnology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37119343?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+industrial+ecology&rft.atitle=The+road+to+green+nanotechnology&rft.au=Karn%2C+Barbara&rft.aulast=Karn&rft.aufirst=Barbara&rft.date=2008-06-01&rft.volume=12&rft.issue=3&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=Journal+of+industrial+ecology&rft.issn=10881980&rft_id=info:doi/10.1111%2Fj.1530-9290.2008.00045.x LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - Nanotechnology; 4339; 12434; 8662 12622; 6397 10242 3872 554 971 DO - http://dx.doi.org/10.1111/j.1530-9290.2008.00045.x ER - TY - JOUR T1 - Altered gene expression in the brain and liver of female fathead minnows Pimephales promelas Rafinesque exposed to fadrozole AN - 21015451; 8386637 AB - The fathead minnow Pimephales promelas is a small fish species widely used for ecotoxicology research and regulatory testing in North America. This study used a 2000 gene oligonucleotide microarray to evaluate the effects of the aromatase inhibitor, fadrozole, on gene expression in the liver and brain tissue of exposed females. Reproductive measures, plasma vitellogenin and gene expression data for the brain isoform of aromatase (cytP19B), vitellogenin precursors and transferrin provided evidence supporting the efficacy of the fadrozole exposure. Unsupervised analysis of the microarray results identified 20 genes in brain and 41 in liver as significantly up-regulated and seven genes in brain and around 45 in liver as significantly down-regulated. Differentially expressed genes were associated with a broad spectrum of biological functions, many with no obvious relationship to aromatase inhibition. However, in brain, fadrozole exposure elicited significant up-regulation of several genes involved in the cholesterol synthesis, suggesting it as a potentially affected pathway. Gene ontology-based analysis of expression changes in liver suggested overall down-regulation of protein biosynthesis. While real-time polymerase chain reaction analyses supported some of the microarray responses, others could not be verified. Overall, results of this study provide a foundation for developing novel hypotheses regarding the system-wide effects of fadrozole, and other chemical stressors with similar modes of action, on fish biology. JF - Journal of Fish Biology AU - Villeneuve, D L AU - Knoebl, I AU - Larkin, P AU - Miracle, AL AU - Carter, B J AU - Denslow, N D AU - Ankley, G T AD - US EPA, ORD, NHEERL, Mid-Continent Ecology Division, 6201 Congdon Blvd, Duluth, MN 55804, U.S.A., villeneuve.dan@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 2281 EP - 2340 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 72 IS - 9 SN - 0022-1112, 0022-1112 KW - Genetics Abstracts; CSA Neurosciences Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - North America KW - Biosynthesis KW - Data processing KW - Protein biosynthesis KW - Nucleotide sequence KW - Brain KW - Environmental impact KW - Cholesterol KW - Freshwater KW - Freshwater fish KW - Oligonucleotides KW - Gene expression KW - Pimephales promelas KW - Transferrin KW - Aromatase KW - Ecotoxicology KW - Vitellogenin KW - Liver KW - Polymerase chain reaction KW - Inhibitors KW - Females KW - N3 11023:Neurogenetics KW - Q5 08504:Effects on organisms KW - Q1 08344:Reproduction and development KW - G 07700:Molecular Genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21015451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Fish+Biology&rft.atitle=Altered+gene+expression+in+the+brain+and+liver+of+female+fathead+minnows+Pimephales+promelas+Rafinesque+exposed+to+fadrozole&rft.au=Villeneuve%2C+D+L%3BKnoebl%2C+I%3BLarkin%2C+P%3BMiracle%2C+AL%3BCarter%2C+B+J%3BDenslow%2C+N+D%3BAnkley%2C+G+T&rft.aulast=Villeneuve&rft.aufirst=D&rft.date=2008-06-01&rft.volume=72&rft.issue=9&rft.spage=2281&rft.isbn=&rft.btitle=&rft.title=Journal+of+Fish+Biology&rft.issn=00221112&rft_id=info:doi/10.1111%2Fj.1095-8649.2008.01897.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-09-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Gene expression; Biosynthesis; Ecotoxicology; Nucleotide sequence; Environmental impact; Brain; Inhibitors; Females; Freshwater fish; Transferrin; Protein biosynthesis; Data processing; Aromatase; Vitellogenin; Liver; Polymerase chain reaction; Cholesterol; Oligonucleotides; Pimephales promelas; North America; Freshwater DO - http://dx.doi.org/10.1111/j.1095-8649.2008.01897.x ER - TY - JOUR T1 - Multilateral Protection of Large Lakes AN - 21014948; 8334662 AB - Late last year, by Lake Victoria's north shore in Kampala, Uganda, the 53 member states of the Commonwealth of Nations signed an agreement that lays out a shared understanding of climate change and the policies needed to address it (http://www.thecommonwealth.org/ documenf/34293/35144/173014/climateactionplan.htm). While the plan is a critical step forward for sustainability, Victoria is more than a backdrop: it is the world's second-largest freshwater lake and an important ecosystem that has supported considerable biodiversity (http://biology.mcgill.ca/faculty/chapman/articles/108_BioScience. pdf); still serves as a crucial resource for the region in terms of food, water, and livelihoods (http://www.eac.int/LVDP/basin.htm); and forms a boundary between Uganda, Kenya, and Tanzania. And, as with most other lacustrine ecosystems with international borders, it is bedeviled by a long list of environmental problems, including climate change. Successful ecosystem management of such water bodies hinges on the ability of neighboring countries to work together, adapting to environmental impacts through multilateral institutions or regimes. JF - Environment (Washington DC) AU - Haugland, J AD - U.S. Environmental Protection Agency's Great Lakes National Program Office, USA Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 3 VL - 50 IS - 3 SN - 0013-9157, 0013-9157 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts; Sustainability Science Abstracts; Aqualine Abstracts KW - Environmental Effects KW - shores KW - Resource management KW - Tanzania KW - Ecosystems KW - water bodies KW - Freshwater lakes KW - freshwater lakes KW - Uganda, Kampala KW - Climate change KW - Climatic changes KW - Shores KW - Biological diversity KW - Biodiversity KW - Ecological Effects KW - Lakes KW - Ecosystem management KW - Climatic Changes KW - sustainability KW - Environmental impact KW - Uganda KW - Institutions KW - Africa, Victoria L. KW - Foods KW - Boundaries KW - AQ 00001:Water Resources and Supplies KW - Q5 08523:Conservation, wildlife management and recreation KW - M2 551.583:Variations (551.583) KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21014948?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environment+%28Washington+DC%29&rft.atitle=Multilateral+Protection+of+Large+Lakes&rft.au=Haugland%2C+J&rft.aulast=Haugland&rft.aufirst=J&rft.date=2008-06-01&rft.volume=50&rft.issue=3&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Environment+%28Washington+DC%29&rft.issn=00139157&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Resource management; Freshwater lakes; Climatic changes; Environmental impact; Ecosystem management; Biodiversity; Climate change; shores; Lakes; water bodies; freshwater lakes; Biological diversity; sustainability; Environmental Effects; Foods; Ecosystems; Boundaries; Shores; Climatic Changes; Institutions; Ecological Effects; Africa, Victoria L.; Tanzania; Uganda, Kampala; Uganda ER - TY - JOUR T1 - Tier risk assessments of biopesticides AN - 20957420; 8354518 AB - Pesticides manufactured from naturally-occuring substances (e.g., pheromones), microorganisms (e.g., Bacillus thuringiensis) and genetically-modified organisms are designated as biopesticides. They are distinguished from conventional chemical pesticides by their unique modes of action, low volume use, target species specificity or natural occurrence, and are important components in IPM strategies. Before a pesticide is registered in the U.S., critical science-based risk assessments of pesticides are conducted, which help to provide public confidence. The Office of Pesticide Programs (OPP) in the (U.S. Environmental Protection Agency (US EPA) uses the standard tiered risk assessment paradigm of analyzing hazards and exposures to assess pesticidal risks to human health and to the environment. Under a tiered structure, potential risks are determined first from estimates of hazard and exposure under "worst-case" scenarios (Tier I). Subsequent testing (Tiers II, III and IV) may be required to assess adverse effects under more realistic conditions and when lower-tiered studies suggest potentially unacceptable risks. These estimates are developed from a synthesis of test results, intended uses and the open literature to fulfill data requirements addressing the primary disciplines of product analysis and manufacturing, mammalian health and ecological/environmental effects. The U.S. EPA has over 30 years of regulatory experience in preparing risk assessments for registering biopesticides. In 1984, the U.S. EPA first published pesticide data requirements for all pesticides, subsequently these requirements have been modified periodically to refine the risk assessment and eliminate unnecessary testing for biopesticides. The biopesticide data requirements were recently updated, clarified and revised in December 2007. The poster presentation will provide an overview of a risk assessment, relevant definitions and updated revisions of the current data requirements for the registration of a biopesticide. JF - Phytopathology AU - Tomimatsu, G S AU - Schneider, W R AD - U.S. Environmental Protection Agency, OPPTS/OPP/BPPD, Washington, DC 20460, USA Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 1 VL - 98 IS - 6 SN - 0031-949X, 0031-949X KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology; Biotechnology and Bioengineering Abstracts KW - Risk assessment KW - Data processing KW - Pheromones KW - Genetically engineered microorganisms KW - Bacillus thuringiensis KW - Reviews KW - Pesticides KW - Environmental effects KW - Side effects KW - W 30925:Genetic Engineering KW - A 01360:Plant Diseases KW - J 02420:Plant Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20957420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Phytopathology&rft.atitle=Tier+risk+assessments+of+biopesticides&rft.au=Tomimatsu%2C+G+S%3BSchneider%2C+W+R&rft.aulast=Tomimatsu&rft.aufirst=G&rft.date=2008-06-01&rft.volume=98&rft.issue=6&rft.spage=S157&rft.isbn=&rft.btitle=&rft.title=Phytopathology&rft.issn=0031949X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Data processing; Pheromones; Genetically engineered microorganisms; Reviews; Pesticides; Environmental effects; Side effects; Bacillus thuringiensis ER - TY - JOUR T1 - Dynamic evaluation of regional air quality models: Assessing changes in O sub(3) stemming from changes in emissions and meteorology AN - 20924835; 8341785 AB - Regional-scale air quality models are used to estimate the response of air pollutants to potential emission control strategies as part of the decision-making process. Traditionally, the model-predicted pollutant concentrations are evaluated for the ''base case'' to assess a model's ability to reproduce past observations. Dynamic evaluation approaches, which evaluate a model's ability to accurately simulate air quality changes from given changes in emissions, are critically important to regulatory applications. Here, we investigate approaches to evaluate the Community Multiscale Air Quality (CMAQ) model's predicted ozone (O sub(3)) response to large NO sub(x) emission reductions associated with the NO sub(x) State Implementation Plan (SIP) Call and on-road mobile emissions. This case has the advantages that emission changes associated with the NO sub(x) SIP Call can be well characterized and substantial changes are observed in O sub(3) levels. To consider the modeled response to emission changes in light of the strong meteorological influences on O sub(3), two time periods after the NO sub(x) SIP Call are included with very different meteorological conditions. The sensitivity to chemical mechanisms is also considered by including simulations with the CB4, SAPRC, and CB05 chemical mechanisms. The evaluation results suggest that the air quality model predictions underestimate the O sub(3) reductions observed after the NO sub(x) SIP Call was implemented. While the emission estimate uncertainties may also be a factor, the results suggest that the contribution of long-range transport of O sub(3) and precursors is underpredicted, especially when using the CB4 chemical mechanism. Further investigation of the chemical mechanisms' ability to characterize tropospheric chemistry aloft is recommended. Results based on the most recent CMAQ version 4.6 with CB05 and updated emission inventories show incremental improvements to the modeled O sub(3) response to NO sub(x) emission reductions. JF - Atmospheric Environment AU - Gilliland, AB AU - Hogrefe, C AU - Pinder, R W AU - Godowitch, J M AU - Foley, K L AU - Rao, ST AD - Air Resources Laboratory, National Oceanic and Atmospheric Administration, Research Triangle Park, NC 27711, USA, gilliland.alice@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 5110 EP - 5123 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 20 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - Air pollution control KW - Air quality KW - Ozone in troposphere KW - Emission inventories KW - Emissions KW - Meteorology KW - Meteorological conditions KW - Ozone KW - Atmospheric pollution KW - Simulation KW - Troposphere KW - Emission control KW - Air quality models KW - Tropospheric chemistry KW - Air pollution KW - Long-range transport KW - Numerical simulations KW - Atmospheric chemistry KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20924835?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Dynamic+evaluation+of+regional+air+quality+models%3A+Assessing+changes+in+O+sub%283%29+stemming+from+changes+in+emissions+and+meteorology&rft.au=Gilliland%2C+AB%3BHogrefe%2C+C%3BPinder%2C+R+W%3BGodowitch%2C+J+M%3BFoley%2C+K+L%3BRao%2C+ST&rft.aulast=Gilliland&rft.aufirst=AB&rft.date=2008-06-01&rft.volume=42&rft.issue=20&rft.spage=5110&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2008.02.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Ozone in troposphere; Long-range transport; Atmospheric pollution; Atmospheric pollution models; Numerical simulations; Meteorology; Air quality; Meteorological conditions; Tropospheric chemistry; Air quality models; Ozone; Air pollution; Emission inventories; Atmospheric chemistry; Emissions; Troposphere; Simulation; Air pollution control; Emission control DO - http://dx.doi.org/10.1016/j.atmosenv.2008.02.018 ER - TY - JOUR T1 - Water-remoteness for grazing relief in Australian arid-lands AN - 20915579; 8297886 AB - Commercial grazing is possible over much of arid Australia due to a high density of artificial watering points. The broadscale supplementation of drinking water has not only enhanced densities of sheep (Ovies aries), cattle (Bos taurus, Bos indicus) and goats (Capra hircus), but has also contributed to increased populations of native kangaroos (Macropus spp.) since pre-European times. Empirical data are compiled to identify threshold distances from water containing 95% of a population of grazing animals. For sheep the proposed threshold is 3km, 6km for cattle and 7km for red kangaroos. Despite clear evidence of water-focussed grazing, evidence of decreased biodiversity in relation to distance to water is scant and conflicting between studies. Reasons for this include the limited power of sampling designs and further research is required to establish the value of water-remote areas as grazing-relief refuges and to demonstrate that the recovery of grazing sensitive species is achievable after grazing relief has been restored. An eastern Australian case study indicates that within some large areas used for commercial pastoralism, the density of water points is such that there is nowhere further than 7km from water. Where water-remote areas persist, their maintenance should be paramount. In the context of rangeland pastoralism and high densities of water points, de-stocking and water-point closure over large areas will be the most effective means of achieving grazing relief and will require strategic land acquisition. JF - Biological Conservation AU - Fensham, R J AU - Fairfax, R J AD - Environmental Protection Agency, Mt. Coot-tha Road, Toowong, Qld. 4066, Australia, rod.fensham@epa.qld.gov.au Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 1447 EP - 1460 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 141 IS - 6 SN - 0006-3207, 0006-3207 KW - Sustainability Science Abstracts; Ecology Abstracts KW - grazing KW - Grazing KW - Capra hircus KW - Biological diversity KW - Biodiversity KW - Bos taurus KW - Maintenance KW - Supplementation KW - case studies KW - Rangelands KW - Cattle KW - Bos indicus KW - Conservation KW - Australia KW - sheep KW - Macropus KW - Sampling KW - Drinking water KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20915579?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Conservation&rft.atitle=Water-remoteness+for+grazing+relief+in+Australian+arid-lands&rft.au=Fensham%2C+R+J%3BFairfax%2C+R+J&rft.aulast=Fensham&rft.aufirst=R&rft.date=2008-06-01&rft.volume=141&rft.issue=6&rft.spage=1447&rft.isbn=&rft.btitle=&rft.title=Biological+Conservation&rft.issn=00063207&rft_id=info:doi/10.1016%2Fj.biocon.2008.03.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Rangelands; Grazing; Biodiversity; Conservation; Sampling; Drinking water; Supplementation; case studies; Cattle; grazing; Biological diversity; sheep; Maintenance; Bos indicus; Capra hircus; Macropus; Bos taurus; Australia DO - http://dx.doi.org/10.1016/j.biocon.2008.03.016 ER - TY - JOUR T1 - Evaluation of a direct personal coarse particulate matter monitor AN - 20873680; 8298388 AB - One aspect of the North Carolina Adult Asthma and Environment study (NCAAES) was to evaluate personal exposures to coarse particulate matter (PM sub(1) sub(0) sub(-) sub(2) sub(.) sub(5)) and their associated variability. As part of this, we examined the ability of a community-based monitor to act as a surrogate for an individual's true exposure to this size fraction in linked health effect studies. To assess personal exposures to various particulate matter (PM) size fractions, a personal PM monitor was evaluated. This monitor featured a multi-stage cascade impactor that allowed for the simultaneous collection of PM sub(1) sub(0) sub(-) sub(2) sub(.) sub(5) and PM sub(2) sub(.) sub(5) size fractions. The monitor was evaluated for collocated bias and comparability with a dichotomous (dichot) sampler (device for dividing aerosol PM population into two size fractions during sampling) at an outdoor monitoring site. Results of this evaluation indicated that the prototype was capable of agreement within +/-20% of that provided by the reference methodology as well as 20% daily precision for PM sub(1) sub(0) sub(-) sub(2) sub(.) sub(5) mass measurements. JF - Atmospheric Environment AU - Case, M W AU - Williams, R AU - Yeatts, K AU - Chen, F-L AU - Scott, J AU - Svendsen, E AU - Devlin, R B AD - United States Environmental Protection Agency (EPA), Human Studies Facility, 104 Mason Farm Road, Chapel Hill, Research Triangle Park, NC 27599, USA, mwcase@mebtel.net Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 4446 EP - 4452 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 19 SN - 1352-2310, 1352-2310 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Particle size KW - USA, North Carolina KW - Pollution monitoring KW - Aerosols KW - Atmospheric pollution KW - prototypes KW - Aerosol samplers KW - Asthma KW - Particulates KW - Respiratory diseases KW - community involvement KW - Air pollution KW - Particulate matter in atmosphere KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20873680?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Evaluation+of+a+direct+personal+coarse+particulate+matter+monitor&rft.au=Case%2C+M+W%3BWilliams%2C+R%3BYeatts%2C+K%3BChen%2C+F-L%3BScott%2C+J%3BSvendsen%2C+E%3BDevlin%2C+R+B&rft.aulast=Case&rft.aufirst=M&rft.date=2008-06-01&rft.volume=42&rft.issue=19&rft.spage=4446&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2008.02.023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Particulate matter in atmosphere; Atmospheric pollution; Aerosol samplers; Asthma; Particle size; Air pollution; Pollution monitoring; Aerosols; prototypes; Respiratory diseases; Particulates; community involvement; USA, North Carolina DO - http://dx.doi.org/10.1016/j.atmosenv.2008.02.023 ER - TY - JOUR T1 - Modeling effects of natural flow restoration on metals fate and transport in a mountain stream impacted by mine waste AN - 20865680; 8307349 AB - The effects of natural flow restoration on metals fate and transport in the Upper Tenmile Creek Watershed, Montana, were modeled using the Water Quality Analysis Simulation Program developed by the U.S. Environmental Protection Agency (USEPA). This 50-km super(2) watershed has over 150 historic abandoned mines, including mine waste rock and tailings, as well as adits discharging acid mine drainage, and is the primary drinking water supply for the City of Helena. Water supply diversions almost completely dewater some stream reaches during summer low flows, but the city is considering a new drinking water source and restoration of natural flows in Tenmile Creek as part of acid mine drainage remediation and broader aquatic habitat restoration. One dimensional steady-state simulation of total recoverable cadmium, copper, lead, and zinc in the mainstem was performed, and the model was calibrated to June 2000 base-flow data. Representative low-flows in August and high-flow snowmelt conditions in June were modeled using mean monthly natural flow estimates from the U.S. Geological Survey and representative USEPA metals concentrations data. The modeling showed that total recoverable metals concentrations, and especially loads, can vary significantly among input locations and over time in the watershed. Some data gaps limit evaluation of variability and increase uncertainty in several locations. Model results indicated, however, that natural low- and high-flow restoration by itself can reduce some metals concentrations in the mainstem compared to June 2000 values, which were influenced by significant water diversion. Some values (such as Zn) may still exceed standards during natural August low flow due to the remaining high concentrations and loads in the primary inputs to the mainstem. Others (such as Cu) can increase during high flow due to remaining mine waste sources and loading of particulate Cu associated with erosion and transport of solids. Greater than 50% reduction in concentrations and loads from some of the main tributaries may be necessary to meet all standards, especially for potential particulate loads with higher flows in June. JF - Journal of the American Water Resources Association AU - Caruso, B S AU - Cox, T J AD - Wetlands and Watersheds Unit, USEPA Region 8, 1595 Wynkoop St, Denver, Colorado 80202, USA, caruso.brian@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 535 EP - 551 VL - 44 IS - 3 SN - 1093-474X, 1093-474X KW - Pollution Abstracts; Aqualine Abstracts; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts; Water Resources Abstracts KW - Acidic wastes KW - Bioremediation KW - Heavy metals KW - Water resources KW - Freshwater KW - Water quality KW - Watersheds KW - Water supplies KW - Lead KW - Mountains KW - Radioactive waste disposal underground KW - Tributaries KW - Metals KW - Acid Mine Drainage KW - Environmental protection KW - Model Studies KW - Stream flow KW - EPA KW - Numerical simulations KW - Habitat improvement KW - Natural Flow KW - Mine Wastes KW - Drainage water KW - Snow melting KW - geological surveys KW - Particulates KW - Streams KW - Mine tailings KW - Drinking Water KW - Mining wastes KW - Metal concentrations KW - USA, Florida, Tenmile Creek KW - Water sources KW - USA, Montana KW - Urban areas KW - Drainage KW - Low Flow KW - Simulation KW - Water supply KW - Erosion KW - Water wells KW - Drinking water KW - AQ 00007:Industrial Effluents KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - ENA 16:Renewable Resources-Water KW - Q5 08521:Mechanical and natural changes KW - M2 556.12:Precipitation (556.12) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20865680?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Modeling+effects+of+natural+flow+restoration+on+metals+fate+and+transport+in+a+mountain+stream+impacted+by+mine+waste&rft.au=Caruso%2C+B+S%3BCox%2C+T+J&rft.aulast=Caruso&rft.aufirst=B&rft.date=2008-06-01&rft.volume=44&rft.issue=3&rft.spage=535&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2008.00180.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Heavy metals; Habitat improvement; Water resources; Watersheds; Tributaries; Mine tailings; Lead; Drainage water; Water supply; Stream flow; Snow melting; Radioactive waste disposal underground; Erosion; Numerical simulations; Drainage; Water sources; Water quality; Environmental protection; Metals; Bioremediation; Acidic wastes; geological surveys; Simulation; Particulates; Streams; Water supplies; Mountains; EPA; Mining wastes; Metal concentrations; Water wells; Drinking water; Urban areas; Drinking Water; Acid Mine Drainage; Natural Flow; Low Flow; Mine Wastes; Model Studies; USA, Florida, Tenmile Creek; USA, Montana; Freshwater DO - http://dx.doi.org/10.1111/j.1752-1688.2008.00180.x ER - TY - JOUR T1 - Observed and modeled seasonal trends in dissolved and particulate Cu, Fe, Mn, and Zn in a mining-impacted stream AN - 20860601; 8298947 AB - North Fork Clear Creek (NFCC) in Colorado, an acid-mine drainage (AMD) impacted stream, was chosen to examine the distribution of dissolved and particulate Cu, Fe, Mn, and Zn in the water column, with respect to seasonal hydrologic controls. NFCC is a high-gradient stream with discharge directly related to snowmelt and strong seasonal storms. Additionally, conditions in the stream cause rapid precipitation of large amounts of hydrous iron oxides (HFO) that sequester metals. Because AMD-impacted systems are complex, geochemical modeling may assist with predictions and/or confirmations of processes occurring in these environments. This research used Visual-MINTEQ to determine if field data collected over a two and one-half year study would be well represented by modeling with a currently existing model, while limiting the number of processes modeled and without modifications to the existing model's parameters. Observed distributions between dissolved and particulate phases in the water column varied greatly among the metals, with average dissolved fractions being >90% for Mn, ~75% for Zn, ~30% for Cu, and <10% for Fe. A strong seasonal trend was observed for the metals predominantly in the dissolved phase (Mn and Zn), with increasing concentrations during base-flow conditions and decreasing concentrations during spring-runoff. This trend was less obvious for Cu and Fe. Within hydrologic seasons, storm events significantly influenced in-stream metals concentrations. The most simplified modeling, using solely sorption to HFO, gave predicted percentage particulate Cu results for most samples to within a factor of two of the measured values, but modeling data were biased toward over-prediction. About one-half of the percentage particulate Zn data comparisons fell within a factor of two, with the remaining data being under-predicted. Slightly more complex modeling, which included dissolved organic carbon (DOC) as a solution phase ligand, significantly reduced the positive bias between observed and predicted percentage particulate Cu, while inclusion of hydrous manganese oxide (HMO) yielded model results more representative of the observed percentage particulate Zn. These results indicate that there is validity in the use of an existing model, without alteration and with typically collected water chemistry data, to describe complex natural systems, but that processes considered optimal for one metal might not be applicable for all metals in a given water sample. JF - Water Research AU - Butler, BA AU - Ranville, J F AU - Ross, P E AD - Colorado School of Mines, Golden, CO 80401, USA, Barbara.Butler@epa.gov Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 3135 EP - 3145 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl] VL - 42 IS - 12 SN - 0043-1354, 0043-1354 KW - Pollution Abstracts; Aqualine Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Sustainability Science Abstracts; Water Resources Abstracts KW - Iron oxides KW - Water sampling KW - Water Analysis KW - Particulates KW - Freshwater KW - Streams KW - Storms KW - Hydrologic Models KW - Sulfur dioxide KW - Zinc KW - manganese oxides KW - Dissolved organic carbon KW - Seasonal variations KW - Manganese KW - Metals KW - Sorption KW - Seasonal Distribution KW - Drainage KW - Geochemistry KW - River discharge KW - Manganese oxides KW - ASW, USA, Florida, New Estuary, North Fork KW - USA, Colorado KW - Snowmelt KW - water column KW - drainage water KW - Iron KW - Ligands KW - SW 5010:Network design KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - AQ 00002:Water Quality KW - Q5 08501:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20860601?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Research&rft.atitle=Observed+and+modeled+seasonal+trends+in+dissolved+and+particulate+Cu%2C+Fe%2C+Mn%2C+and+Zn+in+a+mining-impacted+stream&rft.au=Butler%2C+BA%3BRanville%2C+J+F%3BRoss%2C+P+E&rft.aulast=Butler&rft.aufirst=BA&rft.date=2008-06-01&rft.volume=42&rft.issue=12&rft.spage=3135&rft.isbn=&rft.btitle=&rft.title=Water+Research&rft.issn=00431354&rft_id=info:doi/10.1016%2Fj.watres.2008.03.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Sorption; Iron oxides; River discharge; Particulates; Manganese oxides; Dissolved organic carbon; Manganese; Iron; Ligands; Metals; Water sampling; Drainage; Geochemistry; Storms; Sulfur dioxide; manganese oxides; Snowmelt; drainage water; water column; Seasonal variations; Seasonal Distribution; Hydrologic Models; Water Analysis; Zinc; Streams; USA, Colorado; ASW, USA, Florida, New Estuary, North Fork; Freshwater DO - http://dx.doi.org/10.1016/j.watres.2008.03.004 ER - TY - JOUR T1 - Comparing trophic position of stream fishes using stable isotope and gut contents analyses AN - 20445630; 9126738 AB - Rybczynski SM, Walters DM, Fritz KM, Johnson BR. Comparing trophic position of stream fishes using stable isotope and gut contents analyses.Ecology of Freshwater Fish 2008: 17: 199-206. [copy 2007 The Authors. Journal compilation [copy 2007 Blackwell MunksgaardAbstract-Stable isotope analysis (SIA) and gut contents analysis (GCA) are commonly used in food web studies, but few studies analyse these data in concert. We used SIA ( delta 15N) and GCA (% composition) to identify diets and trophic position (TP) of six stream fishes and to compare TP estimates between methods. Ordination analysis of gut contents identified two primary trophic groups, omnivores and predators. Significant differences in TPGCA and TPSIA were similar in direction among-species and among-trophic groups; neither method detected seasonal changes in omnivore diets. Within-species TPGCA and TPSIA were similar except for one omnivore. TPGCA was less variable than TPSIA for predators, but variation between methods was similar for omnivores. While both methods were equally robust at discriminating trophic groups of fishes, TPSIA is less laborious to estimate and may facilitate cross-stream comparisons of food web structure and energy flow. JF - Ecology of Freshwater Fish AU - Rybczynski, S M AU - Walters, D M AU - Fritz, K M AU - Johnson, B R AD - U.S. Environmental Protection Agency, National Exposure Research Laboratory, Ecological Exposure Research Division, Cincinnati, OH, USA, rybczysm@muohio.edu Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 199 EP - 206 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 17 IS - 2 SN - 0906-6691, 0906-6691 KW - Ecology Abstracts; ASFA 1: Biological Sciences & Living Resources KW - diet KW - delta 15N KW - omnivory KW - nongame fish KW - feeding habits KW - Diets KW - Isotopes KW - Omnivores KW - Predators KW - Freshwater KW - Freshwater fish KW - Streams KW - Pisces KW - Energy flow KW - Digestive tract KW - Trophic structure KW - Nitrogen isotopes KW - Ordination KW - Seasonal variations KW - Food webs KW - Q1 08482:Ecosystems and energetics KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20445630?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecology+of+Freshwater+Fish&rft.atitle=Comparing+trophic+position+of+stream+fishes+using+stable+isotope+and+gut+contents+analyses&rft.au=Rybczynski%2C+S+M%3BWalters%2C+D+M%3BFritz%2C+K+M%3BJohnson%2C+B+R&rft.aulast=Rybczynski&rft.aufirst=S&rft.date=2008-06-01&rft.volume=17&rft.issue=2&rft.spage=199&rft.isbn=&rft.btitle=&rft.title=Ecology+of+Freshwater+Fish&rft.issn=09066691&rft_id=info:doi/10.1111%2Fj.1600-0633.2007.00289.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Energy flow; Omnivores; Trophic structure; Nitrogen isotopes; Freshwater fish; Seasonal variations; Food webs; Diets; Isotopes; Digestive tract; Predators; Ordination; Streams; Pisces; Freshwater DO - http://dx.doi.org/10.1111/j.1600-0633.2007.00289.x ER - TY - JOUR T1 - Quantification of Phenol, Phenyl Glucuronide, and Phenyl Sulfate in Blood of Unanesthetized Rainbow Trout by Online Microdialysis Sampling AN - 20251828; 8883082 AB - Free concentrations of phenol (PH), phenyl glucuronide (PG), and phenyl sulfate (PS) were measured in the bloodstream of unanesthetized rainbow trout by online microdialysis (MD) sampling. Preliminary studies were conducted to optimize the MD system and evaluate three retrodialysis calibration standards: p-nitrophenyl glucuronide (PNPG), p-nitrophenyl sulfate (PNPS), and [14C]-phenol (14C-PH). PG and PNPG exhibited nearly identical dialyzing properties in vitro (saline and plasma) and in vivo (muscle tissue and dorsal aorta). A similar result was obtained for PS and PNPS. In vivo studies were therefore performed using PNPG, PNPS, and 14C-PH as retrodialysis calibrators for PG, PS, and PH, respectively. The utility of MD sampling for kinetic studies with fish was investigated by implanting MD probes into the dorsal aorta of spinally transected rainbow trout. Each fish was then exposed to PH in water in a respirometer-metabolism chamber. The free concentration of PH in blood reached a steady-state level within 12 h of initiating the exposure. A steady state for PS was generally established within 24 h, while free concentrations of PG tended to increase throughout the exposure. Terminal plasma samples were dialyzed using the same probe employed in each experiment. Analyte concentrations determined in this manner were in good agreement with calculated in vivo values. The methods described in this study can be used to collect kinetic data sets of high temporal resolution while eliminating artifacts often associated with conventional blood sampling methods. JF - Toxicology Mechanisms and Methods AU - Nichols, John W AU - Hoffman, Alex D AU - Fitzsimmons, Patrick N AU - Lien, Gregory J AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, U.S. Environmental Protection Agency, Duluth, Minnesota Y1 - 2008/06// PY - 2008 DA - June 2008 SP - 405 EP - 412 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk] VL - 18 IS - 5 SN - 1537-6516, 1537-6516 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Toxicology Abstracts KW - Data processing KW - Aorta KW - Probes KW - Muscles KW - Oncorhynchus mykiss KW - Phenols KW - Sulfate KW - Microdialysis KW - Blood KW - Serological studies KW - Fish physiology KW - Kinetics KW - p-Nitrophenyl KW - p-nitrophenyl sulfate KW - Sampling KW - Toxicology KW - Q5 08504:Effects on organisms KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20251828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+Mechanisms+and+Methods&rft.atitle=Quantification+of+Phenol%2C+Phenyl+Glucuronide%2C+and+Phenyl+Sulfate+in+Blood+of+Unanesthetized+Rainbow+Trout+by+Online+Microdialysis+Sampling&rft.au=Nichols%2C+John+W%3BHoffman%2C+Alex+D%3BFitzsimmons%2C+Patrick+N%3BLien%2C+Gregory+J&rft.aulast=Nichols&rft.aufirst=John&rft.date=2008-06-01&rft.volume=18&rft.issue=5&rft.spage=405&rft.isbn=&rft.btitle=&rft.title=Toxicology+Mechanisms+and+Methods&rft.issn=15376516&rft_id=info:doi/10.1080%2F15376510701511935 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Blood; Serological studies; Fish physiology; Sampling; Toxicology; Phenols; Microdialysis; Data processing; Aorta; Kinetics; Muscles; Probes; p-nitrophenyl sulfate; p-Nitrophenyl; Sulfate; Oncorhynchus mykiss DO - http://dx.doi.org/10.1080/15376510701511935 ER - TY - JOUR T1 - Improved real-time PCR assays for the detection of fecal indicator bacteria in surface waters with different instrument and reagent systems AN - 20241805; 8271061 AB - Previously reported and redesigned primer and probe assays were evaluated for the quantitative analysis of the fecal indicator bacterial groups, Enterococcus and Bacteroidetes with three realtime PCR instrument and reagent systems. The efficiency and sensitivity of the original assays varied between systems in analyses of DNA extracts from pure cultures of Enterococcus faecalis and Bacteroides fragilis, whereas the modified assays gave more consistent results. Distinctions between original and modified assays also occurred in analyses of known spike levels of E. faecalis and B. fragilis cells on filters with diverse surface water retentates. Percentages of samples causing PCR failures due to inhibition were lower using the modified assays. The accuracy and precision of spiked bacteria measurements were also generally higher, although mean measurements of both target organisms were still significantly different between systems (p < 0.05). The accuracy and precision of spiked bacteria measurements by both modified assays were further improved using a new sample matrix control spike consisting of cultured Lactococcus lactis cells and a reference assay for this organism. Corrections provided by the L. lactis assay eliminated significant differences in E. faecalis measurements between all three systems and between two of the three systems in B. fragilis measurements. JF - Journal of Water and Health AU - Siefring, S AU - Varma, M AU - Atikovic, E AU - Wymer, L AU - Haugland, R A AD - U.S. Environmental Protection Agency (EPA), National Exposure Research Laboratory, Cincinnati, OH, USA, hsugland.rich@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 225 EP - 238 VL - 6 IS - 2 SN - 1477-8920, 1477-8920 KW - Microbiology Abstracts B: Bacteriology; Aqualine Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Environment Abstracts; Water Resources Abstracts KW - Bacteroides fragilis KW - Fecal coliforms KW - Assay KW - Polymerase chain reaction KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - A 01300:Methods KW - SW 2010:Control of water on the surface KW - ENA 07:General KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20241805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+and+Health&rft.atitle=Improved+real-time+PCR+assays+for+the+detection+of+fecal+indicator+bacteria+in+surface+waters+with+different+instrument+and+reagent+systems&rft.au=Siefring%2C+S%3BVarma%2C+M%3BAtikovic%2C+E%3BWymer%2C+L%3BHaugland%2C+R+A&rft.aulast=Siefring&rft.aufirst=S&rft.date=2008-06-01&rft.volume=6&rft.issue=2&rft.spage=225&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+and+Health&rft.issn=14778920&rft_id=info:doi/10.2166%2Fwh.2008.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Fecal coliforms; Assay; Bacteroides fragilis DO - http://dx.doi.org/10.2166/wh.2008.022 ER - TY - JOUR T1 - A comparison of single and multiple habitat protocols for collecting macroinvertebrates in wadeable streams AN - 20226761; 8307352 AB - In 2003, we compared two benthic macroinvertebrate sampling methods that are used for rapid biological assessment of wadeable streams. A single habitat method using kick sampling in riffles and runs was compared to a multiple habitat method that sampled all available habitats in proportion of occurrence. Both methods were performed side-by-side at 41 sites in lower gradient streams of the Piedmont and Northern Pied-mont ecoregions of the United States, where riffle habitat is less abundant. Differences in sampling methods were examined using similarity indices, two multimetric indices [the family-level Virginia Stream Condition Index (VSCI) and the species-level Macroinvertebrate Biotic Integrity Index (MBII)], their component metrics, and bioassessment endpoints based on each index. Index scores were highly correlated between single and mul-tiple habitat field methods, and sampling method comparability, based on comparison of similarities between and within sampling methods, was particularly high for species level data. The VSCI scores and values of most of its component metrics were not significantly higher for one particular method, but relationships between single and multiple habitat values were highly variable for percent Ephemeroptera, percent chironomids, and percent Plecoptera and Trichoptera (Hydropsychidae excluded). A similar level of variability in the relationship was observed for the MBII and most of its metrics, but Ephemeroptera richness, percent individuals in the dominant five taxa, and Hilsenhoff Biotic Index scores all exhibited differences in values between single and multiple habitat field methods. When applied to multiple habitat samples, the MBII exhibited greater precision, higher index scores, and higher assessment categories than when applied to single habitat samples at the same sites. In streams with limited or no riffle habitats, the multiple habitat method should provide an adequate sample for biological assessment, and at sites with abundant riffle habitat, little difference would be expected between the single and multiple habitat field methods. Thus, in geographic areas with a wide variety of stream types, the multiple habitat method may be more desirable. Even so, the variability in the relationship between single and multiple habitat methods indicates that the data are not interchangeable, and we suggest that any change in sampling method should be accompanied by a recalibration of any existing assessment tool (e.g., multimetric index) with data collected using the new method, regardless of taxonomic level. JF - Journal of the American Water Resources Association AU - Blocksom, KA AU - Autrey, B C AU - Passmore, M AU - Reynolds, L AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, 26 W. Martin Luther King Drive, Cincinnati, Ohio 45268, USA, blocksom.karen@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 577 EP - 593 VL - 44 IS - 3 SN - 1093-474X, 1093-474X KW - Aqualine Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources; Environment Abstracts; Water Resources Abstracts; Entomology Abstracts KW - Variability KW - Plecoptera KW - Water resources KW - Macroinvertebrates KW - taxa KW - Streams KW - Hydropsychidae KW - Comparative studies KW - Habitats KW - Assessments KW - Ephemeroptera KW - taxonomy KW - Sampling KW - Aquatic insects KW - Trichoptera KW - Data processing KW - USA, Virginia KW - Habitat KW - Insects KW - Aquatic Habitats KW - Taxonomy KW - Zoobenthos KW - Riffles KW - Sampling methods KW - AQ 00001:Water Resources and Supplies KW - Q1 08462:Benthos KW - Z 05340:Ecology and Behavior KW - Q2 09127:General papers on resources KW - SW 0835:Streamflow and runoff KW - M3 1010:Issues in Sustainable Development KW - ENA 16:Renewable Resources-Water KW - Q5 08501:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20226761?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=A+comparison+of+single+and+multiple+habitat+protocols+for+collecting+macroinvertebrates+in+wadeable+streams&rft.au=Blocksom%2C+KA%3BAutrey%2C+B+C%3BPassmore%2C+M%3BReynolds%2C+L&rft.aulast=Blocksom&rft.aufirst=KA&rft.date=2008-06-01&rft.volume=44&rft.issue=3&rft.spage=577&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2008.00183.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Comparative studies; Water resources; Taxonomy; Sampling; Habitat; Zoobenthos; Aquatic insects; Data processing; Streams; taxonomy; taxa; Sampling methods; Variability; Habitats; Assessments; Aquatic Habitats; Macroinvertebrates; Insects; Riffles; Hydropsychidae; Plecoptera; Ephemeroptera; Trichoptera; USA, Virginia DO - http://dx.doi.org/10.1111/j.1752-1688.2008.00183.x ER - TY - JOUR T1 - Detection and Assessment of Ecosystem Regime Shifts from Fisher Information AN - 20056980; 8612094 AB - Ecosystem regime shifts, which are long-term system reorganizations, have profound implications for sustainability. There is a great need for indicators of regime shifts, particularly methods that are applicable to data from real systems. We have developed a form of Fisher information that measures dynamic order in complex systems. Here we propose the use of Fisher information as a means of: (1) detecting dynamic regime shifts in ecosystems, and (2) assessing the quality of the shift in terms of intensity and pervasiveness. Intensity is reflected by the degree of change in dynamic order, as determined by Fisher information, and pervasiveness is a reflection of how many observable variables are affected by the change. We present a new robust methodology to calculate Fisher information from time series field data. We demonstrate the use of Fisher information to detect regime shifts on a model for a shallow lake. Next, we use Fisher information to analyze marine ecosystem response to physical changes using real time-series data of a coastal marine ecosystem, the North Pacific Ocean. JF - Ecology and Society AU - Karunanithi, A T AU - Cabezas, H AU - Frieden, B R AU - Pawlowski, C W AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Cincinnati, OH 45268, USA Y1 - 2008/06// PY - 2008 DA - Jun 2008 VL - 13 IS - 1 SN - 1708-3087, 1708-3087 KW - Pollution Abstracts; Ecology Abstracts; Sustainability Science Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Hydrological Regime KW - Resource management KW - Ecosystems KW - Indicators KW - Freshwater KW - Models KW - Lakes KW - IN, North Pacific KW - Assessments KW - Marine environment KW - sustainability KW - Marine ecosystems KW - Environmental monitoring KW - Marine KW - Data processing KW - time series analysis KW - Brackish KW - Inland water environment KW - Model Studies KW - marine ecosystems KW - Oceans KW - Q5 08523:Conservation, wildlife management and recreation KW - SW 0850:Lakes KW - Q2 09123:Conservation KW - P 2000:FRESHWATER POLLUTION KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20056980?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecology+and+Society&rft.atitle=Detection+and+Assessment+of+Ecosystem+Regime+Shifts+from+Fisher+Information&rft.au=Karunanithi%2C+A+T%3BCabezas%2C+H%3BFrieden%2C+B+R%3BPawlowski%2C+C+W&rft.aulast=Karunanithi&rft.aufirst=A&rft.date=2008-06-01&rft.volume=13&rft.issue=1&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Ecology+and+Society&rft.issn=17083087&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Resource management; Marine environment; Inland water environment; Lakes; Data processing; Oceans; Marine ecosystems; Models; marine ecosystems; time series analysis; sustainability; Hydrological Regime; Assessments; Ecosystems; Indicators; Model Studies; IN, North Pacific; Freshwater; Brackish; Marine ER - TY - JOUR T1 - Do 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline data support the conclusion of threshold carcinogenic effects? AN - 19896656; 8313018 AB - The objectives of this paper are to (1) reexamine the data that were used to support the conclusion of a threshold effect for 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline (MeIQx)-induced initiation and carcinogenicity at low doses in the rat liver, and (2) discuss issues and uncertainties about assessing cancer risk at low doses. Our analysis is part of an effort to understand proper interpretation and modeling of data related to cancer mechanisms and is not an effort to develop a risk assessment for this compound. The data reanalysis presented herein shows that the low-dose initiation activity of MeIQx, which can be found in cooked meat, cannot be dismissed. It is argued that the threshold effect for carcinogenic agents cannot be determined by statistical non-significance alone; more relevant biological information is required. A biologically motivated procedure is proposed for data analyses. The concept and procedure that are appropriate for analyzing MeIQx data are equally applicable to other compounds with comparable data. JF - Stochastic Environmental Research and Risk Assessment AU - Chen, Chao AU - Guyton, Kate Z AD - U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW, Mail code 8623-D, Washington, DC, 20460, USA, chen.chao@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 487 EP - 494 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 22 IS - 4 SN - 1436-3240, 1436-3240 KW - Toxicology Abstracts KW - Risk assessment KW - Meat KW - Data processing KW - Statistics KW - Carcinogenicity KW - Risk factors KW - quinoxaline KW - Liver KW - Stochasticity KW - Cancer KW - X 24320:Food Additives & Contaminants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19896656?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Stochastic+Environmental+Research+and+Risk+Assessment&rft.atitle=Do+2-amino-3%2C8-dimethylimidazo%5B4%2C5-f%5D+quinoxaline+data+support+the+conclusion+of+threshold+carcinogenic+effects%3F&rft.au=Chen%2C+Chao%3BGuyton%2C+Kate+Z&rft.aulast=Chen&rft.aufirst=Chao&rft.date=2008-06-01&rft.volume=22&rft.issue=4&rft.spage=487&rft.isbn=&rft.btitle=&rft.title=Stochastic+Environmental+Research+and+Risk+Assessment&rft.issn=14363240&rft_id=info:doi/10.1007%2Fs00477-007-0150-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Meat; Risk assessment; Statistics; Data processing; Carcinogenicity; Risk factors; Liver; quinoxaline; Stochasticity; Cancer DO - http://dx.doi.org/10.1007/s00477-007-0150-1 ER - TY - JOUR T1 - Health assessment of phosgene: Approaches for derivation of reference concentration AN - 19814454; 8258228 AB - This paper describes the derivation of the chronic reference concentration (RfC) for human inhalation of phosgene that was recently added to the Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) data base (U.S. EPA, 2005. Toxicological Review of Phosgene: In Support of Summary Information on the Integrated Risk Information System (IRIS). Available online at: ). The RfC is an estimate of daily phosgene exposure to the human population that is likely to be without appreciable risk of deleterious effects during a lifetime. [For this and other definitions relevant to EPA risk assessments refer to the glossary of terms in the US EPA IRIS website (http://www.epa.gov/IRIS).] Phosgene is a potential environmental pollutant that is primarily used as a catalyst in the polyurethane industry. It is a gas at room temperature, and in aqueous solution it rapidly hydrolyzes to CO sub(2) and HCl. In the absence of chronic human health effects information and lifetime animal cancer bioassays, the RfC is based on two 12-week inhalation studies in F344 rats which measured immune response and pulmonary effects, respectively. The immune response study showed impaired clearance of bacteria that was administered into the lungs of rats immediately after exposure to phosgene at concentrations of 0.1, 0.2 and 0.5ppm. It also showed that the immune response in uninfected rats was stimulated by phosgene exposure at all concentrations. The pulmonary effects study showed a progressive concentration-related thickening and inflammation in the bronchiolar regions of the lung that was mild at 0.1ppm and severe at 1.0ppm. An increase in collagen content, as observed with histological collagen stains, was observed at 0.2ppm and above. Though there is considerable uncertainty associated with the species and exposure duration employed, this endpoint is considered an indication of chronic lung injury of potential relevance to humans. Three different approaches for RfC derivation were taken in analyzing these studies: (1) the traditional NOAEL/LOAEL method; (2) the benchmark dose (BMD); and (3) the categorical regression for the analysis of severity-graded pulmonary damage data using the recently revised USEPA CatReg software. The BMD approach was selected as the method of choice to determine the RfC for phosgene because it has several advantages compared to the NOAEL/LOAEL: (1) it is not restricted to the set of doses used in the experiments; (2) the result is not dependent on sample size; (3) it incorporates information on statistical uncertainty. The CatReg approach allowed the incorporation of data on the severity of the pathological lesions, and therefore it complemented the other approaches. The BMD approach could not be applied to the immune response data because it was not possible to define an adverse effect level for bacterial resistance. However, NOAEL/LOAEL values for immune responses were consistent with benchmark dose levels derived from lung pathology data and used in the derivation of the RfC. The preferred RfC method and derivation involved dividing the benchmark dose from the collagen staining data (0.03mg/m super(3)) by a composite uncertainty factor of 100: RfC=0.03/100=3E-4mg/m super(3). JF - Regulatory Toxicology and Pharmacology AU - Gift, J S AU - McGaughy, R AU - Singh, D V AU - Sonawane, B AD - Office of Research and Development, United States Environmental Protection Agency, 1200 Pennsylvania Avenue, Washington, DC 20460, USA, Singh.dharm@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 98 EP - 107 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 51 IS - 1 SN - 0273-2300, 0273-2300 KW - phosgene KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts KW - Inhalation KW - Risk assessment KW - Statistics KW - Injuries KW - Stains KW - Collagen KW - Computer programs KW - software KW - Bone mineral density KW - Pollutants KW - polyurethane KW - Catalysts KW - Data bases KW - Temperature effects KW - Data processing KW - Temperature KW - Cancer KW - Inflammation KW - EPA KW - Databases KW - USA KW - Bioassays KW - benchmarks KW - Lung KW - Reviews KW - Immune response KW - Carbon dioxide KW - Side effects KW - Information systems KW - X 24310:Pharmaceuticals KW - H 14000:Toxicology KW - R2 23060:Medical and environmental health KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19814454?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+Toxicology+and+Pharmacology&rft.atitle=Health+assessment+of+phosgene%3A+Approaches+for+derivation+of+reference+concentration&rft.au=Gift%2C+J+S%3BMcGaughy%2C+R%3BSingh%2C+D+V%3BSonawane%2C+B&rft.aulast=Gift&rft.aufirst=J&rft.date=2008-06-01&rft.volume=51&rft.issue=1&rft.spage=98&rft.isbn=&rft.btitle=&rft.title=Regulatory+Toxicology+and+Pharmacology&rft.issn=02732300&rft_id=info:doi/10.1016%2Fj.yrtph.2008.03.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Inhalation; Temperature effects; Data processing; Statistics; Injuries; Stains; Cancer; Inflammation; Collagen; Databases; Computer programs; software; Bone mineral density; Pollutants; Lung; Reviews; polyurethane; Immune response; Catalysts; Carbon dioxide; phosgene; Side effects; Information systems; Temperature; EPA; Bioassays; benchmarks; Data bases; USA DO - http://dx.doi.org/10.1016/j.yrtph.2008.03.004 ER - TY - JOUR T1 - Complex issues with examining diesel exhaust toxicity: Is the task getting easier or harder? AN - 19811224; 8752147 AB - Petroleum diesel exhaust (DE) exposure has been linked to several health effects including lung cancer. The role of de in the cardiopulmonary effects associated with particulate matter (PM) exposures is unclear; this uncertainty drives current research efforts to better understand how the de exerts toxicity. Several issues present complexities to the design of de health effects research. One issue is to better establish the health effects and biological responses from de exposure. Lung responses have been examined with variable findings with controlled exposures, but to date relatively little is known about cardiovascular responses. Additionally, induction of other health effects from de exposure has been examined mainly through either controlled nonhuman animal model exposures or epidemiological approaches. Due to changing regulations and technology to achieve compliance with regulatory standards, de from more modern emissions contains less PM and certain gases, making comparisons to older emissions complicated. In addition, the gas phase contains proportionally more mass than the PM phase, presenting technological problems in terms of the collection of the de for future studies and across- laboratory comparison. Therefore, in order to study the toxicity of DE, whole exhaust (PM and gases) exposures should ideally be performed, at least as part of establishing the role that the PM or gases may play in the biological responses being examined. JF - Experimental and Toxicologic Pathology AU - Madden, Michael C AD - US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Human Studies Division, Research Triangle Park, NC 27711, USA, madden.michael@epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 135 EP - 140 PB - Elsevier GmbH, Office Jena, P.O. Box 100537 Jena D-07705 Germany, [mailto:journals@elsevier.com], [URL:http://www.elsevier.de/] VL - 60 IS - 2-3 SN - 0940-2993, 0940-2993 KW - Toxicology Abstracts KW - Diesel exhaust KW - Bioassay KW - Mutagenicity KW - Allergy KW - Inflammation KW - Susceptibility KW - Emission regulations KW - Gases KW - Cardiovascular system KW - Petroleum KW - Particulate matter KW - Animal models KW - Diesel KW - Toxicity KW - Exhausts KW - Lung cancer KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19811224?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Experimental+and+Toxicologic+Pathology&rft.atitle=Complex+issues+with+examining+diesel+exhaust+toxicity%3A+Is+the+task+getting+easier+or+harder%3F&rft.au=Madden%2C+Michael+C&rft.aulast=Madden&rft.aufirst=Michael&rft.date=2008-06-01&rft.volume=60&rft.issue=2-3&rft.spage=135&rft.isbn=&rft.btitle=&rft.title=Experimental+and+Toxicologic+Pathology&rft.issn=09402993&rft_id=info:doi/10.1016%2Fj.etp.2008.01.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-04-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Cardiovascular system; Gases; Petroleum; Particulate matter; Animal models; Diesel; Toxicity; Lung cancer; Exhausts DO - http://dx.doi.org/10.1016/j.etp.2008.01.002 ER - TY - JOUR T1 - Application of membrane separation technology in minitype electroplating park wastewater reuse AN - 19763117; 9049026 AB - The feasibility of membrane separation technology in minitype electroplating park water reuse was investigated via analysis of a case. It was demonstrated that it is feasible for electroplating waste water reuse by membrane separation technology, which resolved local shortage situations of water resources and is of definite extrapolability. The system had been running statle for 21 days. Effluent was 10.25m super(3)/h, rejection for salt was 98% and the recovery rate was about 6.4%. The product water could be recirculated to electroplating puoduct line. JF - Technology of Water Treatment AU - Chen, J-F AU - Wu, Z-Y AU - Lou, Y-N AU - Luo, W-F AD - Yuhuan County EPA, Yuhuan 317600, China Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 91 VL - 34 IS - 6 SN - 1000-3770, 1000-3770 KW - Aqualine Abstracts; Water Resources Abstracts KW - Water Reuse KW - Membranes KW - Effluents KW - Impaired Water Use KW - Salts KW - Parks KW - Water Treatment KW - Electroplating KW - Water Resources KW - SW 3040:Wastewater treatment processes KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19763117?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Technology+of+Water+Treatment&rft.atitle=Application+of+membrane+separation+technology+in+minitype+electroplating+park+wastewater+reuse&rft.au=Chen%2C+J-F%3BWu%2C+Z-Y%3BLou%2C+Y-N%3BLuo%2C+W-F&rft.aulast=Chen&rft.aufirst=J-F&rft.date=2008-06-01&rft.volume=34&rft.issue=6&rft.spage=91&rft.isbn=&rft.btitle=&rft.title=Technology+of+Water+Treatment&rft.issn=10003770&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-03-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Impaired Water Use; Salts; Water Reuse; Membranes; Parks; Water Treatment; Electroplating; Effluents; Water Resources ER - TY - JOUR T1 - The effects of river floodwaters on floodplain wetland water quality and diatom assemblages AN - 19554041; 8702733 AB - We investigated the effects of river floodpulses on the water chemistry and diatom assemblages in a floodplain wetland. During the two year study period (November 2003-September 2005), the river and wetland exhibited three periods of surface hydrologic connectivity. The impacts of flooding depended on flood magnitude and duration. Both the long/high magnitude and short/high magnitude floods thoroughly mixed river and wetland waters, with conductivity, total nitrogen, and total phosphorus in the wetland decreasing to levels similar to the river. In contrast, the short/low magnitude flood did not mix water chemistry. Wetland conductivity, total nitrogen, and total phosphorus remained elevated. Changes in algal biomass followed changes in water chemistry with the high magnitude floods producing conditions unfavorable for algal growth. Algal biomass decreased in the wetland coinciding with the two high magnitude floods. Increases in algal biomass coincided with the short/low magnitude flood. Wetland and river water column diatom assemblages were dominated by periphytic taxa. The diatom assemblage in the river and wetland were distinct, except during the short/high magnitude flood. During this period, floodwaters brought diatoms into the wetland and both systems were dominated by planktonic centric taxa. Similar diatom taxa were observed in the wetland water column assemblage and the assemblage collected in settling chambers, although their relative abundances varied. Shifts in the settling diatom assemblage coincided with periods of flooding, indicating that river floodwaters leave a discernable signal within this assemblage. Our findings indicate that caution should be exercised when using diatom-based bioassessment in frequently flooded wetlands as the wetland diatom assemblage is influenced by river floodwaters and changes may depend on the duration and magnitude of flooding. JF - Wetlands AU - Weilhoefer, Christine L AU - Pan, Yangdong AU - Eppard, Sara AD - 1Present address: Western Ecology Division, US EPA, 2111 SE Marine Science Drive, Newport, Oregon, USA 97365 E-mail:, weilhoefer.christineatepamail.epa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 473 EP - 486 PB - Society of Wetland Scientists, P.O. Box 1897 VL - 28 IS - 2 SN - 0277-5212, 0277-5212 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Pollution Abstracts; Ecology Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 1: Biological Sciences & Living Resources KW - algae KW - floodplain KW - floodpulse KW - nitrogen KW - phosphorus KW - sediment trap KW - water quality KW - Bacillariophyceae KW - Phosphorus KW - Diatoms KW - Phytoplankton KW - taxa KW - Freshwater KW - flood plains KW - Water quality KW - Water column KW - Growth KW - Floods KW - Environmental effects KW - Wetlands KW - Sedimentation KW - Floodwater KW - Algae KW - Rivers KW - water chemistry KW - Biomass KW - Flood Plains KW - Flood plains KW - River water KW - Flooding KW - water column KW - Water chemistry KW - Nitrogen KW - Q1 08462:Benthos KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution KW - D 04040:Ecosystem and Ecology Studies KW - Q2 09171:Dynamics of lakes and rivers KW - K 03450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19554041?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Wetlands&rft.atitle=The+effects+of+river+floodwaters+on+floodplain+wetland+water+quality+and+diatom+assemblages&rft.au=Weilhoefer%2C+Christine+L%3BPan%2C+Yangdong%3BEppard%2C+Sara&rft.aulast=Weilhoefer&rft.aufirst=Christine&rft.date=2008-06-01&rft.volume=28&rft.issue=2&rft.spage=473&rft.isbn=&rft.btitle=&rft.title=Wetlands&rft.issn=02775212&rft_id=info:doi/10.1672%2F07-114.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Rivers; Growth; Flood plains; River water; Environmental effects; Flooding; Phytoplankton; Wetlands; Water quality; Floods; Phosphorus; Diatoms; Biomass; Water chemistry; Water column; Nitrogen; Algae; water quality; water chemistry; water column; taxa; flood plains; Flood Plains; Sedimentation; Floodwater; Bacillariophyceae; Freshwater DO - http://dx.doi.org/10.1672/07-114.1 ER - TY - JOUR T1 - Resuspension of Particulate Matter from Carpet Due to Human Activity AN - 19545934; 8590023 AB - This work investigated the resuspension and subsequent translocation of particulate matter (PM) from carpeted flooring surfaces due to walking. In addition, the effect of HVAC systems and ceiling fans on mixing and/or translocation of resuspended PM was studied. Testing took place both in a residence with a well-worn, soiled carpet and in an environmental test chamber. Prescribed walking occurred with PM measurements taken at multiple sampling heights. Scanning electron microscopy (SEM) of carpet fibers was used to determine the fraction of dust available for resuspension. These data, in conjunction with resuspended mass concentrations from this study, were used to generate emission factors by particle size for walking on both new and worn carpet. Carpet loading does not affect the emission factor, indicating that the amount of resuspended PM is directly proportional to the available PM in the carpet. While relative humidity (RH) plays an important role in resuspension from new carpets, with high RH enhancing resuspension, it has the opposite affect with old carpets, with increased RH decreasing resuspension. With the HVAC system on, translocated particles 1.2 m horizontally from the source had number concentrations of approximately 20-40% of those at the source. With a ceiling fan on, extensive mixing was noted with little difference seen in particle resuspension by height. With the ceiling fan off, there was very little mixing present and particle size varied substantially by height. JF - Aerosol Science & Technology AU - Rosati, Jacky A AU - Thornburg, Jonathan AU - Rodes, Charles AD - U.S. Environmental Protection Agency, Office of Research and Development, Research Triangle Park, North Carolina, USA Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 472 EP - 482 PB - Taylor & Francis, 325 Chestnut Street Suite 800 Philadelphia PA 19106 USA, [URL:http://www.taylorandfrancis.com/] VL - 42 IS - 6 SN - 0278-6826, 0278-6826 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Relative humidity KW - Particle size KW - Aerosols KW - Humidity KW - Particulates KW - Dust KW - Microscopy KW - Emission measurements KW - Emissions KW - Human factors KW - translocation KW - Electron microscopy KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19545934?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerosol+Science+%26+Technology&rft.atitle=Resuspension+of+Particulate+Matter+from+Carpet+Due+to+Human+Activity&rft.au=Rosati%2C+Jacky+A%3BThornburg%2C+Jonathan%3BRodes%2C+Charles&rft.aulast=Rosati&rft.aufirst=Jacky&rft.date=2008-06-01&rft.volume=42&rft.issue=6&rft.spage=472&rft.isbn=&rft.btitle=&rft.title=Aerosol+Science+%26+Technology&rft.issn=02786826&rft_id=info:doi/10.1080%2F02786820802187069 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Particulates; Emissions; Particle size; translocation; Humidity; Aerosols; Human factors; Microscopy; Emission measurements; Dust; Relative humidity; Electron microscopy DO - http://dx.doi.org/10.1080/02786820802187069 ER - TY - JOUR T1 - Meta-analysis of benzene exposure and non-Hodgkin lymphoma: biases could mask an important association AN - 19532092; 8202617 AB - OBJECTIVES: Benzene is a widely recognised cause of leukaemia but its association with non-Hodgkin's lymphoma (NHL) is less well established. The goal of this project is to review the current published literature on this association. METHODS: We performed a meta-analysis of cohort and case-control studies of benzene exposure and NHL and a meta-analysis of NHL and refinery work, a potential source of benzene exposure. RESULTS: In 22 studies of benzene exposure, the summary relative risk for NHL was 1.22 (95% CI 1.02 to 1.47; one-sided p value = 0.01). When studies that likely included unexposed subjects in the "exposed" group were excluded, the summary relative risk increased to 1.49 (95% CI 1.12 to 1.97, n = 13), and when studies based solely on self-reported work history were excluded, the relative risk rose to 2.12 (95% CI 1.11 to 4.02, n = 6). In refinery workers, the summary relative risk for NHL in all 21 studies was 1.21 (95% CI 1.00 to 1.46; p = 0.02). When adjusted for the healthy worker effect, this relative risk estimate increased to 1.42 (95% CI 1.19 to 1.69). CONCLUSIONS: The finding of elevated relative risks in studies of both benzene exposure and refinery work provides further evidence that benzene exposure causes NHL. In addition, the finding of increased relative risks after removing studies that included unexposed or lesser exposed workers in "exposed" cohorts, and increased relative risk estimates after adjusting for the healthy worker effect, suggest that effects of benzene on NHL might be missed in occupational studies if these biases are not accounted for. JF - Occupational and Environmental Medicine AU - Steinmaus, C AU - Smith, A H AU - Jones, R M AU - Smith, M T AD - School of Public Health, University of California, Berkeley, California, USA Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, California, USA Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 371 EP - 378 PB - B M J Publishing Group, B.M.A. House Tavistock Sq. London WC1H 9JR UK VL - 65 IS - 6 SN - 1351-0711, 1351-0711 KW - Risk Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts; Immunology Abstracts KW - Risk assessment KW - Historical account KW - Refineries KW - Benzene KW - Workers KW - Non-Hodgkin's lymphoma KW - Leukemia KW - Reviews KW - Occupational exposure KW - R2 23080:Industrial and labor KW - F 06955:Immunomodulation & Immunopharmacology KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19532092?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+and+Environmental+Medicine&rft.atitle=Meta-analysis+of+benzene+exposure+and+non-Hodgkin+lymphoma%3A+biases+could+mask+an+important+association&rft.au=Steinmaus%2C+C%3BSmith%2C+A+H%3BJones%2C+R+M%3BSmith%2C+M+T&rft.aulast=Steinmaus&rft.aufirst=C&rft.date=2008-06-01&rft.volume=65&rft.issue=6&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Occupational+and+Environmental+Medicine&rft.issn=13510711&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Leukemia; Non-Hodgkin's lymphoma; Workers; Reviews; Benzene; Historical account; Refineries; Occupational exposure ER - TY - JOUR T1 - Liver Genomic Responses to Ciguatoxin: Evidence for Activation of Phase I and Phase II Detoxification Pathways following an Acute Hypothermic Response in Mice AN - 19530243; 8204098 AB - Ciguatoxins (CTX) are polyether neurotoxins that target voltage-gated sodium channels and are responsible for ciguatera, the most common fish-borne food poisoning in humans. This study characterizes the global transcriptional response of mouse liver to a symptomatic dose (0.26 ng/g) of the highly potent Pacific ciguatoxin-1 (P-CTX-1). At 1 h post-exposure 2.4% of features on a 44K whole genome array were differentially expressed (p less than or equal to 0.0001), increasing to 5.2% at 4 h and decreasing to 1.4% by 24 h post-CTX exposure. Data were filtered (|fold change| greater than or equal to 1.5 and p less than or equal to 0.0001 in at least one time point) and a trend set of 1550 genes were used for further analysis. Early gene expression was likely influenced prominently by an acute 4 degree C decline in core body temperature by 1 h, which resolved by 8 h following exposure. An initial downregulation of 32 different solute carriers, many involved in sodium transport, was observed. Differential gene expression in pathways involving eicosanoid biosynthesis and cholesterol homeostasis was also noted. Cytochrome P450s (Cyps) were of particular interest due to their role in xenobiotic metabolism. Twenty-seven genes, mostly members of Cyp2 and Cyp4 families, showed significant changes in expression. Many Cyps underwent an initial downregulation at 1 h but were quickly and strongly upregulated at 4 and 24 h post-exposure. In addition to Cyps, increases in several glutathione S-transferases were observed, an indication that both phase I and phase II metabolic reactions are involved in the hepatic response to CTX in mice. JF - Toxicological Sciences AU - Morey, Jeanine S AU - Ryan, James C AU - Bottein Dechraoui, Marie-Yasmine AU - Rezvani, Amir H AU - Levin, Edward D AU - Gordon, Christopher J AU - Ramsdell, John S AU - Van Dolah, Frances M AD - Marine Biotoxins Program, NOAA Center for Coastal Environmental Health and Biomolecular Research, Charleston, South Carolina 29414. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710. Neurotoxicology Division, U. S. EPA, National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina 27711 Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 298 EP - 310 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 103 IS - 2 SN - 1096-6080, 1096-6080 KW - Genetics Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts KW - Detoxification KW - Genomes KW - Sodium channels (voltage-gated) KW - eicosanoids KW - Body temperature KW - Xenobiotics KW - Homeostasis KW - Glutathione transferase KW - Solutes KW - I, Pacific KW - genomics KW - Biosynthesis KW - Data processing KW - Temperature KW - Food poisoning KW - Transcription KW - Mice KW - Cholesterol KW - Food contamination KW - cholesterol KW - Ciguatera KW - Channels KW - Sodium KW - polyethers KW - Cytochrome KW - Liver KW - Ciguatoxin KW - Cytochrome P450 KW - Neurotoxins KW - Metabolism KW - X 24320:Food Additives & Contaminants KW - G 07870:Mammals KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19530243?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Liver+Genomic+Responses+to+Ciguatoxin%3A+Evidence+for+Activation+of+Phase+I+and+Phase+II+Detoxification+Pathways+following+an+Acute+Hypothermic+Response+in+Mice&rft.au=Morey%2C+Jeanine+S%3BRyan%2C+James+C%3BBottein+Dechraoui%2C+Marie-Yasmine%3BRezvani%2C+Amir+H%3BLevin%2C+Edward+D%3BGordon%2C+Christopher+J%3BRamsdell%2C+John+S%3BVan+Dolah%2C+Frances+M&rft.aulast=Morey&rft.aufirst=Jeanine&rft.date=2008-06-01&rft.volume=103&rft.issue=2&rft.spage=298&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Genomes; Detoxification; Data processing; Sodium channels (voltage-gated); Body temperature; eicosanoids; Transcription; Food poisoning; Cholesterol; Homeostasis; Glutathione transferase; Ciguatera; Solutes; polyethers; Liver; Cytochrome P450; Ciguatoxin; genomics; Neurotoxins; Metabolism; Biosynthesis; Temperature; Mice; Xenobiotics; Food contamination; cholesterol; Sodium; Channels; Cytochrome; I, Pacific ER - TY - JOUR T1 - Brazilian Free-tailed Bats as Insect Pest Regulators in Transgenic and Conventional Cotton Crops AN - 19528520; 8228588 AB - During the past 12000 years agricultural systems have transitioned from natural habitats to conventional agricultural regions and recently to large areas of genetically engineered (GE) croplands. This GE revolution occurred for cotton in a span of slightly more than a decade during which a switch occurred in major cotton production areas from growing 100% conventional cotton to an environment in which 95% transgenics are grown. Ecological interactions between GE targeted insects and other insectivorous insects have been investigated. However, the relationships between ecological functions (such as herbivory and ecosystem transport) and agronomic benefits of avian or mammalian insectivores in the transgenic environment generally remain unclear, although the importance of some agricultural pest management services provided by insectivorous species such as the Brazilian free-tailed bat, Tadarida brasiliensis, have been recognized. We developed a dynamic model to predict regional-scale ecological functions in agricultural food webs by using the indicators of insect pest herbivory measured by cotton boll damage and insect emigration from cotton. In the south-central Texas Winter Garden agricultural region we find that the process of insectivory by bats has a considerable impact on both the ecology and valuation of harvest in Bacillus thuringiensis (Bt) transgenic and non-transgenic cotton crops. Predation on agricultural pests by insectivorous bats may enhance the economic value of agricultural systems by reducing the frequency of required spraying and delaying the ultimate need for new pesticides. In the Winter Garden region, the presence of large numbers of insectivorous bats yields a regional summer dispersion of adult pest insects from Bt cotton that is considerably reduced from the moth emigration when bats are absent in either transgenic or non-transgenic crops. This regional decrease of pest numbers impacts insect herbivory on a transcontinental scale. With a few exceptions, we find that the agronomics of both Bt and conventional cotton production is more profitable when large numbers of insectivorous bats are present. JF - Ecological Applications AU - Federico, P AU - Hallam, T G AU - McCracken, G F AU - Purucker, ST AU - Grant, W E AU - Correa-Sandoval, AN AU - Westbrook, J K AU - Medellin, R A AU - Cleveland, C J AU - Sansone, C G AU - Lopez, JD Jr AU - Betke, M AU - Moreno-Valdez, A AU - Kunz, TH AD - Ecosystems Research Division, National Exposure Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, 960 College Station Road, Athens, Georgia 30605 USA, thallam@utk.edu Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 826 EP - 837 VL - 18 IS - 4 SN - 1051-0761, 1051-0761 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology; Biotechnology and Bioengineering Abstracts; Sustainability Science Abstracts; Entomology Abstracts; Ecology Abstracts KW - Emigration KW - Crop KW - Cotton KW - Bacillus thuringiensis KW - Predation KW - Herbivory KW - Tadarida brasiliensis KW - Pest control KW - Habitat KW - Spraying KW - Crops KW - Models KW - Genetic engineering KW - Economics KW - Pesticides KW - Insectivores KW - Pests KW - Food webs KW - J 02410:Animal Diseases KW - W 30925:Genetic Engineering KW - Z 05340:Ecology and Behavior KW - M3 1010:Issues in Sustainable Development KW - G 07800:Plants and Algae KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19528520?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Applications&rft.atitle=Brazilian+Free-tailed+Bats+as+Insect+Pest+Regulators+in+Transgenic+and+Conventional+Cotton+Crops&rft.au=Federico%2C+P%3BHallam%2C+T+G%3BMcCracken%2C+G+F%3BPurucker%2C+ST%3BGrant%2C+W+E%3BCorrea-Sandoval%2C+AN%3BWestbrook%2C+J+K%3BMedellin%2C+R+A%3BCleveland%2C+C+J%3BSansone%2C+C+G%3BLopez%2C+JD+Jr%3BBetke%2C+M%3BMoreno-Valdez%2C+A%3BKunz%2C+TH&rft.aulast=Federico&rft.aufirst=P&rft.date=2008-06-01&rft.volume=18&rft.issue=4&rft.spage=826&rft.isbn=&rft.btitle=&rft.title=Ecological+Applications&rft.issn=10510761&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Crop; Emigration; Cotton; Herbivory; Predation; Pest control; Spraying; Habitat; Crops; Models; Genetic engineering; Pesticides; Economics; Insectivores; Pests; Food webs; Bacillus thuringiensis; Tadarida brasiliensis ER - TY - JOUR T1 - Applying a Reverse Auction to Reduce Stormwater Runoff AN - 19403009; 8702020 JF - Ambio AU - Thurston, Hale W AU - Taylor, Michael A AU - Roy, Allison AU - Morrison, Matthew AU - Shuster, William D AU - Templeton, Joshua AU - Clagett, Matthew AU - Cabezas, Heriberto AD - Hale W. Thurston US EPA Office of Research and Development National Risk Management Research Laboratory Sustainable Technology Division/ Sustainable Environments Branch 26 W. Martin Luther King Drive Cincinnati, OH 45268, USA, thurston.haleatepa.gov Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 326 EP - 327 PB - Royal Swedish Academy of Sciences VL - 37 IS - 4 SN - 0044-7447, 0044-7447 KW - Meteorological & Geoastrophysical Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Storm Runoff KW - Rainfall runoff KW - Cadmium KW - AQ 00001:Water Resources and Supplies KW - SW 0835:Streamflow and runoff KW - M2 556.16:Runoff (556.16) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19403009?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ambio&rft.atitle=Applying+a+Reverse+Auction+to+Reduce+Stormwater+Runoff&rft.au=Thurston%2C+Hale+W%3BTaylor%2C+Michael+A%3BRoy%2C+Allison%3BMorrison%2C+Matthew%3BShuster%2C+William+D%3BTempleton%2C+Joshua%3BClagett%2C+Matthew%3BCabezas%2C+Heriberto&rft.aulast=Thurston&rft.aufirst=Hale&rft.date=2008-06-01&rft.volume=37&rft.issue=4&rft.spage=326&rft.isbn=&rft.btitle=&rft.title=Ambio&rft.issn=00447447&rft_id=info:doi/10.1579%2F0044-7447%282008%29372.0.CO%3B2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Rainfall runoff; Storm Runoff; Cadmium DO - http://dx.doi.org/10.1579/0044-7447(2008)37[326:AARATR]2.0.CO;2 ER - TY - JOUR T1 - An index of compositional dissimilarity between observed and expected assemblages AN - 19401395; 8694712 AB - The reference-condition approach to bioassessment often uses the observed/expected (O/E) ratio to indicate anthropogenic alteration of aquatic macroinvertebrates, fish, or periphyton assemblages. Given a list of taxa found at greater than or equal to 1 minimally disturbed reference sites, E is the number of those taxa that would expected in a sampled assemblage if the sampled stream were in reference condition, and O is the number of those taxa observed in the sample. An O/E value significantly <1.0 indicates that a stream has lost taxa relative to its reference-condition expectation, possibly because of anthropogenic stress. However, the O/E index can be insensitive to stress-induced shifts in taxonomic composition that leave assemblage richness unchanged. As an alternative to O/E, I propose using BC, an adaptation of Bray-Curtis distance, to measure the compositional dissimilarity between an observed and expected assemblage directly. I compared the performance of BC and O/E at 5685 stream and lake sites throughout the contiguous 48 states of the US using 1 of 10 River Invertebrate Prediction and Classification system (RIVPACS)-type models to predict expected assemblages. Percentages of independently determined nonreference sites that were declared to be nonreference by BC exceeded the percentage declared to be nonreference by O/E by an average of 6 to 16 percentage points, depending on whether the 2 indices included low-probability taxa, whether a 1-sided or 2-sided O/E criterion was used to declare nonreference, and whether predictive or null models were used to predict expected assemblages. Correlations between BC scores and anthropogenic stressor variables were stronger than correlations between O/E scores and anthropogenic stressor variables in 18 of 25 cases. In contrast to O/E, BC can include low-probability taxa without reducing its power to detect nonreference conditions. JF - Journal of the North American Benthological Society AU - Van Sickle, John AD - National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, 200 SW 35th St., Corvallis, Oregon 97333 USA Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 227 EP - 235 PB - Allen Press, Inc., 810 East Tenth St. VL - 27 IS - 2 SN - 0887-3593, 0887-3593 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts; ASFA 1: Biological Sciences & Living Resources KW - predictive model KW - reference condition KW - macroinvertebrate assemblage KW - bioassessment KW - O/E KW - Rivers KW - Prediction KW - Classification systems KW - Adaptations KW - Anthropogenic factors KW - Stress KW - Streams KW - Models KW - Lakes KW - Periphyton KW - Zoobenthos KW - Q1 08422:Environmental effects KW - D 04040:Ecosystem and Ecology Studies KW - K 03320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19401395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+North+American+Benthological+Society&rft.atitle=An+index+of+compositional+dissimilarity+between+observed+and+expected+assemblages&rft.au=Van+Sickle%2C+John&rft.aulast=Van+Sickle&rft.aufirst=John&rft.date=2008-06-01&rft.volume=27&rft.issue=2&rft.spage=227&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+North+American+Benthological+Society&rft.issn=08873593&rft_id=info:doi/10.1899%2F07-111.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Classification systems; Prediction; Adaptations; Anthropogenic factors; Periphyton; Zoobenthos; Rivers; Lakes; Stress; Streams; Models DO - http://dx.doi.org/10.1899/07-111.1 ER - TY - JOUR T1 - Experimental study on activated carbon adsorbing hydroquinone AN - 19397989; 8373971 AB - Under static condition, hydroquinone-containing wastewater was treated by activated carbon, the adsorption effects of activated carbon for hydroquinone -containing wastewater under different conditions were compared, meanwhile, the influences of pH value, activated carbon dosage, oscillation time, temperature, concentration of hydroquinone, oscillation velocity and electrolyte of the wastewater on adsorption effect were determined. The results of the test showed that: under the condition that, the dosage of activated carbon was 35 g/L, the pH value was 6.5, the oscillation time was 3.5 h, the temperature was about 35 degree C, the best treatment effect of hydroquinone-containing wastewater whose mass concentration was 100 mg/L was obtained, the removal rate reached 99%. JF - Industrial Water & Wastewater AU - Yang, K AD - Environmental Protection Agency of Yanshi in Henan Province, Yanshi 471900, China, yk1207@sina.com Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - 62 EP - 64 VL - 39 IS - 3 SN - 1009-2455, 1009-2455 KW - Aqualine Abstracts KW - Electrolytes KW - Industrial Wastewater KW - Adsorption KW - Temperature KW - Industrial Water KW - Hydrogen Ion Concentration KW - Velocity KW - Wastewater KW - Activated Carbon KW - AQ 00007:Industrial Effluents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19397989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Water+%26+Wastewater&rft.atitle=Experimental+study+on+activated+carbon+adsorbing+hydroquinone&rft.au=Yang%2C+K&rft.aulast=Yang&rft.aufirst=K&rft.date=2008-06-01&rft.volume=39&rft.issue=3&rft.spage=62&rft.isbn=&rft.btitle=&rft.title=Industrial+Water+%26+Wastewater&rft.issn=10092455&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Electrolytes; Industrial Wastewater; Industrial Water; Temperature; Adsorption; Velocity; Hydrogen Ion Concentration; Wastewater; Activated Carbon ER - TY - JOUR T1 - Environmental impact of atmospheric NH sub(3) emissions under present and future conditions in the eastern United States AN - 1520387160; 19639861 AB - Recent regulations require large-scale emission reductions of NO sub(x) and SO sub(2) in the eastern United States. These emission changes will alter the partitioning of ammonia between the gas and particle phases. Furthermore, ammonia emissions are expected to increase in the future. How will these changes impact the contribution of ammonia to inorganic particulate matter and nitrogen deposition? We use a chemical transport model and emission scenarios representing years 2001, 2010, and 2020 to estimate the future change of the sensitivity of iPM sub(2.5) to ammonia emission reductions and change in nitrogen deposition to ecosystems. We find that during winter conditions, particulate matter concentrations in several locations in the Midwestern US continue to have significant sensitivity to NH sub(3) emissions. In addition, the total nitrogen deposition near NH sub(3) emission sources increases 10-40% JF - Geophysical Research Letters AU - Pinder, R W AU - Gilliland, AB AU - Dennis, R L AD - Atmospheric Modeling Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA. Y1 - 2008/06// PY - 2008 DA - Jun 2008 SP - [np] PB - American Geophysical Union, 2000 Florida Ave., N.W. Washington DC 20009 United States VL - 35 IS - 12 SN - 0094-8276, 0094-8276 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - ammonia KW - nitrogen deposition KW - particulate matter KW - Sensitivity KW - Atmospheric pollution models KW - Ecosystems KW - Ammonia KW - Chemical transport KW - Environmental impact KW - Ammonia content of atmosphere KW - Emission control KW - Particulates KW - Suspended particulate matter KW - Ecosystem disturbance KW - Winter KW - USA KW - Sulfur dioxide KW - Nitrogen deposition KW - Particulate matter emissions KW - Ammonia emissions KW - Emissions KW - Nitrogen compounds KW - Oxides KW - Nitrogen KW - M2 551.510.42:Air Pollution (551.510.42) KW - Q2 09188:Atmospheric chemistry KW - P 0000:AIR POLLUTION KW - O 2050:Chemical Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1520387160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geophysical+Research+Letters&rft.atitle=Environmental+impact+of+atmospheric+NH+sub%283%29+emissions+under+present+and+future+conditions+in+the+eastern+United+States&rft.au=Pinder%2C+R+W%3BGilliland%2C+AB%3BDennis%2C+R+L&rft.aulast=Pinder&rft.aufirst=R&rft.date=2008-06-01&rft.volume=35&rft.issue=12&rft.spage=%5Bnp%5D&rft.isbn=&rft.btitle=&rft.title=Geophysical+Research+Letters&rft.issn=00948276&rft_id=info:doi/10.1029%2F2008GL033732 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Environmental impact; Suspended particulate matter; Nitrogen compounds; Ecosystem disturbance; Oxides; Atmospheric pollution models; Nitrogen deposition; Ecosystems; Particulate matter emissions; Ammonia emissions; Ammonia content of atmosphere; Sensitivity; Sulfur dioxide; Ammonia; Chemical transport; Emissions; Emission control; Particulates; Winter; Nitrogen; USA DO - http://dx.doi.org/10.1029/2008GL033732 ER - TY - JOUR T1 - Leaching behavior of mineral processing waste: Comparison of batch and column investigations AN - 19683155; 8289259 AB - In this study, a comparison of laboratory batch and column experiments on metal release profile from a mineral processing waste (MPW) is presented. Batch (equilibrium) and column (dynamic) leaching tests were conducted on ground MPW at different liquid-solid ratios (LS) to determine the mechanisms controlling metal release. Additionally, the effect of pH on metal release is also discussed. It was observed that acidic pH conditions induced dissolution of As, Zn and Cu. Negligible leaching at alkaline pH was observed. However, Se depicted amphoteric behavior with high release at low and high pH. The batch and column data showed that As and Se release increased with LS ratio, while that of Cu and Zn increased initially and tapered towards equilibrium values at high LS ratios. The results on metal release from the MPW suggested that dissolution of the metal was the controlling mechanism. Leaching profiles from the batch and column data corresponded well for most LS ratios. This is most likely due to the acidic character of the waste, minimal changes in pH during the column operation and granular structure of the waste. From a waste management perspective, low cost batch equilibrium studies in lieu of high cost column experiments can be used for decision making on its disposal only when the waste exhibits characteristics similar to the mineral processing waste. JF - Journal of Hazardous Materials AU - Al-Abed AU - Jegadeesan, G AU - Purandare, J AU - Allen, D AD - U.S. Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, OH 45268, United States, al-abed.souhail@epa.gov Y1 - 2008/05/30/ PY - 2008 DA - 2008 May 30 SP - 1088 EP - 1092 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 153 IS - 3 SN - 0304-3894, 0304-3894 KW - Pollution Abstracts; Toxicology Abstracts KW - Metals KW - Leaching KW - Data processing KW - Laboratory testing KW - Copper KW - Decision making KW - Zinc KW - mineral processing KW - Dissolution KW - Waste disposal KW - pH effects KW - Minerals KW - pH KW - X 24360:Metals KW - P 4000:WASTE MANAGEMENT UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19683155?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hazardous+Materials&rft.atitle=Leaching+behavior+of+mineral+processing+waste%3A+Comparison+of+batch+and+column+investigations&rft.au=Al-Abed%3BJegadeesan%2C+G%3BPurandare%2C+J%3BAllen%2C+D&rft.aulast=Al-Abed&rft.aufirst=&rft.date=2008-05-30&rft.volume=153&rft.issue=3&rft.spage=1088&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hazardous+Materials&rft.issn=03043894&rft_id=info:doi/10.1016%2Fj.jhazmat.2007.09.063 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Decision making; Metals; Data processing; Leaching; Zinc; Dissolution; Copper; Minerals; pH effects; Laboratory testing; mineral processing; Waste disposal; pH DO - http://dx.doi.org/10.1016/j.jhazmat.2007.09.063 ER - TY - CPAPER T1 - Home on the Big River, Part II: Great River Habitat Quality Indices T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40947809; 4858814 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Taylor, Debra L AU - Pearson, Mark S AU - Angradi, Theodore R AU - Bolgrien, David W AU - Hill, Brian H AU - Jicha, Terri M AU - Moffett, Mary F Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - USA, Indiana, Great R. KW - New Zealand, South I., Kahurangi Natl. Park, Big R. KW - Habitat KW - Rivers KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40947809?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Home+on+the+Big+River%2C+Part+II%3A+Great+River+Habitat+Quality+Indices&rft.au=Taylor%2C+Debra+L%3BPearson%2C+Mark+S%3BAngradi%2C+Theodore+R%3BBolgrien%2C+David+W%3BHill%2C+Brian+H%3BJicha%2C+Terri+M%3BMoffett%2C+Mary+F&rft.aulast=Taylor&rft.aufirst=Debra&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Using Propensity Scores to Infer Cause-Effect Relationships in Observational Data T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40947381; 4858800 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Yuan, Lester L AU - Pollard, Amina I AU - Carlisle, Daren M Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Cause-effect relationships KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40947381?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Using+Propensity+Scores+to+Infer+Cause-Effect+Relationships+in+Observational+Data&rft.au=Yuan%2C+Lester+L%3BPollard%2C+Amina+I%3BCarlisle%2C+Daren+M&rft.aulast=Yuan&rft.aufirst=Lester&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Use of Survey Data to Estimate Nutrient Export in the Mississippi River Basin T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40947178; 4858819 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Hill, Brian H AU - Jicha, Terri M AU - Herlihy, Alan T AU - Bolgrien, David W AU - Paulsen, Stephen G Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - USA, Mississippi R. basin KW - Exports KW - River basins KW - Nutrients KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40947178?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=The+Use+of+Survey+Data+to+Estimate+Nutrient+Export+in+the+Mississippi+River+Basin&rft.au=Hill%2C+Brian+H%3BJicha%2C+Terri+M%3BHerlihy%2C+Alan+T%3BBolgrien%2C+David+W%3BPaulsen%2C+Stephen+G&rft.aulast=Hill&rft.aufirst=Brian&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analyzing Causes of Undesirable Effects in Streams Using USEPA's CADDIS Web Site T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40945957; 4858929 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Norton, Susan Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Streams KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40945957?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Analyzing+Causes+of+Undesirable+Effects+in+Streams+Using+USEPA%27s+CADDIS+Web+Site&rft.au=Norton%2C+Susan&rft.aulast=Norton&rft.aufirst=Susan&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Combining Correlated Stressor Variables to Clarify Stressor Effects T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40945592; 4858799 DE: JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Van Sickle, John Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40945592?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Combining+Correlated+Stressor+Variables+to+Clarify+Stressor+Effects&rft.au=Van+Sickle%2C+John&rft.aulast=Van+Sickle&rft.aufirst=John&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Predictive Model for Anti-Degradation Monitoring of the Delaware River Mainstem T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40945131; 4858937 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Blocksom, Karen AU - Flotemersch, Joseph E AU - Limbeck, Robert L AU - Silldorff, Erik Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - USA, Delaware R. KW - Rivers KW - Models KW - Prediction KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40945131?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=A+Predictive+Model+for+Anti-Degradation+Monitoring+of+the+Delaware+River+Mainstem&rft.au=Blocksom%2C+Karen%3BFlotemersch%2C+Joseph+E%3BLimbeck%2C+Robert+L%3BSilldorff%2C+Erik&rft.aulast=Blocksom&rft.aufirst=Karen&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Macroinvertebrate Protocol and Index Development for Puerto Rico Mountain Streams: Effects of an Elevation Gradient T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40943653; 4858744 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Kurtenbach, James P Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Caribbean Sea, Greater Antilles, Puerto Rico KW - Streams KW - Mountains KW - Environmental effects KW - Zoobenthos KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40943653?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Macroinvertebrate+Protocol+and+Index+Development+for+Puerto+Rico+Mountain+Streams%3A+Effects+of+an+Elevation+Gradient&rft.au=Kurtenbach%2C+James+P&rft.aulast=Kurtenbach&rft.aufirst=James&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Urbanization Eliminates Ephemeral and Intermittent Stream Length and Increases Perennial Flow T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40943411; 4858770 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Roy, Allison H AU - Dybas, Angel L AU - Fritz, Ken M AU - Lubbers, Hannah R Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Urbanization KW - Streams KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40943411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Urbanization+Eliminates+Ephemeral+and+Intermittent+Stream+Length+and+Increases+Perennial+Flow&rft.au=Roy%2C+Allison+H%3BDybas%2C+Angel+L%3BFritz%2C+Ken+M%3BLubbers%2C+Hannah+R&rft.aulast=Roy&rft.aufirst=Allison&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Ecological Consequences of Antibiotic Exposure to Periphyton in Naturally Colonizing Stream Mesocosms T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40937792; 4859055 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Quinlan, Erin L AU - Nietch, Christopher T AU - Lazorchak, James M Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Antibiotics KW - Periphyton KW - Streams KW - Mesocosms KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40937792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Ecological+Consequences+of+Antibiotic+Exposure+to+Periphyton+in+Naturally+Colonizing+Stream+Mesocosms&rft.au=Quinlan%2C+Erin+L%3BNietch%2C+Christopher+T%3BLazorchak%2C+James+M&rft.aulast=Quinlan&rft.aufirst=Erin&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of Four Sampling Gears to Collect Invasive Benthic Invertebrates in the St. Louis Harbor, Duluth MN T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40937675; 4859028 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - West, Corlis W AU - Kelly, John R AU - Hoffman, Joel C AU - Trebitz, Anett S AU - Peterson, Gregory S AU - Grigorovich, Igor Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - USA, Minnesota, Duluth KW - Invertebrates KW - Harbors KW - Sampling KW - Manganese KW - Zoobenthos KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40937675?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Comparison+of+Four+Sampling+Gears+to+Collect+Invasive+Benthic+Invertebrates+in+the+St.+Louis+Harbor%2C+Duluth+MN&rft.au=West%2C+Corlis+W%3BKelly%2C+John+R%3BHoffman%2C+Joel+C%3BTrebitz%2C+Anett+S%3BPeterson%2C+Gregory+S%3BGrigorovich%2C+Igor&rft.aulast=West&rft.aufirst=Corlis&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Vulnerabilities of Reference Locations to Interacting Anthropogenic Stressors of Urbanization and Climate Change T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40937347; 4859321 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Bierwagen, Britta G AU - Gerritsen, Jeroen AU - Hamilton, Anna T Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Urbanization KW - Climatic changes KW - Vulnerability KW - Anthropogenic factors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40937347?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Vulnerabilities+of+Reference+Locations+to+Interacting+Anthropogenic+Stressors+of+Urbanization+and+Climate+Change&rft.au=Bierwagen%2C+Britta+G%3BGerritsen%2C+Jeroen%3BHamilton%2C+Anna+T&rft.aulast=Bierwagen&rft.aufirst=Britta&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Updating Invertebrate Trait Classification with Empirically-Defined Environmental Optima T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40936844; 4859211 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Pollard, Amina I AU - Yuan, Lester L AU - Carlisle, Daren M Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Invertebrates KW - Classification KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40936844?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Updating+Invertebrate+Trait+Classification+with+Empirically-Defined+Environmental+Optima&rft.au=Pollard%2C+Amina+I%3BYuan%2C+Lester+L%3BCarlisle%2C+Daren+M&rft.aulast=Pollard&rft.aufirst=Amina&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Path Analyses to Assess the Effects of Nutrients, Light and Sediment Fines on Periphyton and on Invertebrate and Fish Metrics T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40936548; 4858846 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Griffith, Michael B AU - Daniel, F Bernard Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Nutrients KW - Invertebrates KW - Periphyton KW - Sediment pollution KW - Light effects KW - Abiotic factors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40936548?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Path+Analyses+to+Assess+the+Effects+of+Nutrients%2C+Light+and+Sediment+Fines+on+Periphyton+and+on+Invertebrate+and+Fish+Metrics&rft.au=Griffith%2C+Michael+B%3BDaniel%2C+F+Bernard&rft.aulast=Griffith&rft.aufirst=Michael&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Delineating Resource Sheds in Aquatic Ecosystems T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40934004; 4859012 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Raikow, David F AU - Atkinson, Joseph AU - Croley II, Tom Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Aquatic ecosystems KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40934004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Delineating+Resource+Sheds+in+Aquatic+Ecosystems&rft.au=Raikow%2C+David+F%3BAtkinson%2C+Joseph%3BCroley+II%2C+Tom&rft.aulast=Raikow&rft.aufirst=David&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Integration of DNA Barcoding Approaches into Aquatic Bioassessments T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40933488; 4859241 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Jackson, Suzanne AU - Bagley, Mark AU - Friedman, Ellen AU - Turcsanyi, Istvan AU - Swenson, Stephanie AU - Roth, Annette AU - Driskell, Amy AU - Weight, Lee Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Integration KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40933488?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Integration+of+DNA+Barcoding+Approaches+into+Aquatic+Bioassessments&rft.au=Jackson%2C+Suzanne%3BBagley%2C+Mark%3BFriedman%2C+Ellen%3BTurcsanyi%2C+Istvan%3BSwenson%2C+Stephanie%3BRoth%2C+Annette%3BDriskell%2C+Amy%3BWeight%2C+Lee&rft.aulast=Jackson&rft.aufirst=Suzanne&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Are Bryophytes Useful Indicators of Hydrologic Permanence in Forested Headwater Streams? T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40933465; 4859329 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Fritz, Ken M Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Streams KW - Permanence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40933465?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=Are+Bryophytes+Useful+Indicators+of+Hydrologic+Permanence+in+Forested+Headwater+Streams%3F&rft.au=Fritz%2C+Ken+M&rft.aulast=Fritz&rft.aufirst=Ken&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Dark Side of Subsidies: Quantifying Exposure of Riparian Predators to Contaminants Via Stream Insects T2 - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AN - 40933207; 4859351 JF - 56th Annual Meeting of the North American Benthological Society (NABS 2008) AU - Walters, David M AU - Fritz, Ken M AU - Otter, Ryan Y1 - 2008/05/25/ PY - 2008 DA - 2008 May 25 KW - Predators KW - Subsidies KW - Insects KW - Contaminants KW - Streams KW - Aquatic insects KW - Rivers KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40933207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.atitle=The+Dark+Side+of+Subsidies%3A+Quantifying+Exposure+of+Riparian+Predators+to+Contaminants+Via+Stream+Insects&rft.au=Walters%2C+David+M%3BFritz%2C+Ken+M%3BOtter%2C+Ryan&rft.aulast=Walters&rft.aufirst=David&rft.date=2008-05-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+North+American+Benthological+Society+%28NABS+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://nabs.confex.com/nabs/2008/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model. AN - 71639775; 18489778 AB - Bioactivity profiling using high-throughput in vitro assays can reduce the cost and time required for toxicological screening of environmental chemicals and can also reduce the need for animal testing. Several public efforts are aimed at discovering patterns or classifiers in high-dimensional bioactivity space that predict tissue, organ or whole animal toxicological endpoints. Supervised machine learning is a powerful approach to discover combinatorial relationships in complex in vitro/in vivo datasets. We present a novel model to simulate complex chemical-toxicology data sets and use this model to evaluate the relative performance of different machine learning (ML) methods. The classification performance of Artificial Neural Networks (ANN), K-Nearest Neighbors (KNN), Linear Discriminant Analysis (LDA), Naïve Bayes (NB), Recursive Partitioning and Regression Trees (RPART), and Support Vector Machines (SVM) in the presence and absence of filter-based feature selection was analyzed using K-way cross-validation testing and independent validation on simulated in vitro assay data sets with varying levels of model complexity, number of irrelevant features and measurement noise. While the prediction accuracy of all ML methods decreased as non-causal (irrelevant) features were added, some ML methods performed better than others. In the limit of using a large number of features, ANN and SVM were always in the top performing set of methods while RPART and KNN (k = 5) were always in the poorest performing set. The addition of measurement noise and irrelevant features decreased the classification accuracy of all ML methods, with LDA suffering the greatest performance degradation. LDA performance is especially sensitive to the use of feature selection. Filter-based feature selection generally improved performance, most strikingly for LDA. We have developed a novel simulation model to evaluate machine learning methods for the analysis of data sets in which in vitro bioassay data is being used to predict in vivo chemical toxicology. From our analysis, we can recommend that several ML methods, most notably SVM and ANN, are good candidates for use in real world applications in this area. JF - BMC bioinformatics AU - Judson, Richard AU - Elloumi, Fathi AU - Setzer, R Woodrow AU - Li, Zhen AU - Shah, Imran AD - National Center for Computational Toxicology, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. judson.richard@epa.gov Y1 - 2008/05/19/ PY - 2008 DA - 2008 May 19 SP - 241 VL - 9 KW - Index Medicus KW - Sensitivity and Specificity KW - Reproducibility of Results KW - Artificial Intelligence KW - Algorithms KW - Toxicity Tests -- methods KW - Pattern Recognition, Automated -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71639775?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+bioinformatics&rft.atitle=A+comparison+of+machine+learning+algorithms+for+chemical+toxicity+classification+using+a+simulated+multi-scale+data+model.&rft.au=Judson%2C+Richard%3BElloumi%2C+Fathi%3BSetzer%2C+R+Woodrow%3BLi%2C+Zhen%3BShah%2C+Imran&rft.aulast=Judson&rft.aufirst=Richard&rft.date=2008-05-19&rft.volume=9&rft.issue=&rft.spage=241&rft.isbn=&rft.btitle=&rft.title=BMC+bioinformatics&rft.issn=1471-2105&rft_id=info:doi/10.1186%2F1471-2105-9-241 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-27 N1 - Date created - 2008-06-04 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Nat Genet. 2000 Mar;24(3):236-44 [10700175] J Toxicol Environ Health B Crit Rev. 2010 Feb;13(2-4):51-138 [20574894] Bioinformatics. 2000 May;16(5):412-24 [10871264] Comput Chem. 2001 Dec;26(1):5-14 [11765851] Toxicol Pathol. 2002 Jan-Feb;30(1):41-53 [11890475] Science. 2003 Apr 11;300(5617):294-5 [12690189] Bioinformatics. 2003 Jul 1;19(10):1179-82 [12835259] Bioinformatics. 2003 Jul 1;19(10):1183-93 [12835260] Bioinformatics. 2003 Jul 1;19(10):1194-200 [12835261] Lancet. 2003 Nov 1;362(9394):1439-44 [14602436] Clin Pharmacokinet. 2003;42(15):1331-57 [14674787] Nat Rev Genet. 2004 Apr;5(4):262-75 [15131650] Biochem Pharmacol. 2004 Jun 1;67(11):2141-65 [15135310] Science. 2004 Nov 12;306(5699):1138-9 [15542455] Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):261-6 [15625110] Bioinformatics. 2005 Mar 1;21(5):631-43 [15374862] Trends Biotechnol. 2005 Jun;23(6):299-307 [15922082] Bioinformatics. 2005 Aug 1;21(15):3301-7 [15905277] Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):393-7 [15982691] Comb Chem High Throughput Screen. 2005 Nov;8(7):577-87 [16305355] Comb Chem High Throughput Screen. 2005 Nov;8(7):589-94 [16305356] Nat Chem Biol. 2005 Dec;1(7):389-97 [16370374] J Chem Inf Model. 2006 Jan-Feb;46(1):158-67 [16426052] J Toxicol Sci. 2006 Feb;31(1):23-34 [16538041] Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3153-8 [16492761] Toxicol Sci. 2006 Aug;92(2):476-89 [16731579] Nat Biotechnol. 2006 Jul;24(7):805-15 [16841068] J Chem Inf Model. 2006 Jul-Aug;46(4):1549-62 [16859287] Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8 [16864780] Arch Toxicol. 2006 Sep;80(9):580-604 [16598496] BMC Bioinformatics. 2006;7:387 [16919171] BMC Bioinformatics. 2006;7:407 [16959042] Science. 2006 Sep 29;313(5795):1929-35 [17008526] Bioinformatics. 2006 Oct 1;22(19):2430-6 [16870934] Toxicol Sci. 2007 Jan;95(1):5-12 [16963515] Toxicol Sci. 2007 Jul;98(1):5-38 [17569696] J Biol Chem. 2000 May 19;275(20):15122-7 [10748001] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1186/1471-2105-9-241 ER - TY - JOUR T1 - Perfluorinated compounds in house dust from Ohio and North Carolina, USA. AN - 71670595; 18546718 AB - The perfluoroalkyl acids (PFAAs), including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS), have come under increasing scrutiny due to their persistence, global distribution, and toxicity. Given that their human exposure routes remain poorly characterized, the potential role of house dust needs to be more completely evaluated. In this study, new methods for the analysis of 10 PFAAs and three fluorinated telomer alcohols (FTOHs) were developed for dust samples collected from homes (n = 102) and day care centers (n = 10) in Ohio and North Carolina in 2000-2001. FTOHs were measured by GC/ MS and PFAAs were analyzed by LC-MS/MS. PFOS and PFOA were the most prominent compounds detected, occurring in over 95% of the samples at median concentrations of 201 and 142 ng/g of dust, respectively. Maximal concentrations of PFOS were 12 100 ng/g (95th percentile, 2240 ng/g), PFOA 1960 ng/g (95th percentile, 1200 ng/g), and perfluorohexanesulfonate (PFHS) 35 700 ng/g (95th percentile, 2300 ng/g). The 8:2 FTOH, which is volatile and can degrade to PFOA, had a maximum concentration of 1660 ng/g dust (95th percentile, 669 ng/g). These results indicate that perfluorinated compounds are present in house dust at levels that may represent an important pathway for human exposure. JF - Environmental science & technology AU - Strynar, Mark J AU - Lindstrom, Andrew B AD - Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. Y1 - 2008/05/15/ PY - 2008 DA - 2008 May 15 SP - 3751 EP - 3756 VL - 42 IS - 10 SN - 0013-936X, 0013-936X KW - Dust KW - 0 KW - Fluorocarbons KW - Index Medicus KW - Spectrometry, Mass, Electrospray Ionization KW - North Carolina KW - Chromatography, Liquid KW - Quality Control KW - Ohio KW - Fluorocarbons -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71670595?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Perfluorinated+compounds+in+house+dust+from+Ohio+and+North+Carolina%2C+USA.&rft.au=Strynar%2C+Mark+J%3BLindstrom%2C+Andrew+B&rft.aulast=Strynar&rft.aufirst=Mark&rft.date=2008-05-15&rft.volume=42&rft.issue=10&rft.spage=3751&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-11-17 N1 - Date created - 2008-06-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - Assessment of a Point-of-Use Ultrafiltration System for Turbidity and Microbial Pathogen Removal T2 - 2008 World Environmental and Water Resources Congress AN - 40974762; 4871405 JF - 2008 World Environmental and Water Resources Congress AU - Patterson, Craig L AU - Tzillah, Aisha AU - Duffie, Jack AU - Muhammad, Nur Y1 - 2008/05/13/ PY - 2008 DA - 2008 May 13 KW - Turbidity KW - Pathogens KW - Ultrafiltration UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40974762?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+World+Environmental+and+Water+Resources+Congress&rft.atitle=Assessment+of+a+Point-of-Use+Ultrafiltration+System+for+Turbidity+and+Microbial+Pathogen+Removal&rft.au=Patterson%2C+Craig+L%3BTzillah%2C+Aisha%3BDuffie%2C+Jack%3BMuhammad%2C+Nur&rft.aulast=Patterson&rft.aufirst=Craig&rft.date=2008-05-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+World+Environmental+and+Water+Resources+Congress&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/EWRI08_FINALProgramComplete4-23-08.p df LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Impact of Nanoparticles on the Removal of Organic Pollutants by Activated Carbon Adsorption T2 - 2008 World Environmental and Water Resources Congress AN - 40973420; 4871343 JF - 2008 World Environmental and Water Resources Congress AU - Jasper, Anthony J AU - Patterson, Craig L AU - Sinha, Rajib AU - Krishnan, Radha AU - Sorial, George A Y1 - 2008/05/13/ PY - 2008 DA - 2008 May 13 KW - Pollutant removal KW - Activated carbon KW - Adsorption KW - Pollutants KW - Nanoparticles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40973420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+World+Environmental+and+Water+Resources+Congress&rft.atitle=Impact+of+Nanoparticles+on+the+Removal+of+Organic+Pollutants+by+Activated+Carbon+Adsorption&rft.au=Jasper%2C+Anthony+J%3BPatterson%2C+Craig+L%3BSinha%2C+Rajib%3BKrishnan%2C+Radha%3BSorial%2C+George+A&rft.aulast=Jasper&rft.aufirst=Anthony&rft.date=2008-05-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+World+Environmental+and+Water+Resources+Congress&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/EWRI08_FINALProgramComplete4-23-08.p df LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - SSOAP A USEPA Toolbox for SSO Analysis and Control Planning T2 - 2008 World Environmental and Water Resources Congress AN - 40972455; 4871777 JF - 2008 World Environmental and Water Resources Congress AU - Lai, Fu-hsiung (Dennis) AU - Vallabhaneni, Srinivas Y1 - 2008/05/13/ PY - 2008 DA - 2008 May 13 KW - Maintenance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40972455?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+World+Environmental+and+Water+Resources+Congress&rft.atitle=SSOAP+A+USEPA+Toolbox+for+SSO+Analysis+and+Control+Planning&rft.au=Lai%2C+Fu-hsiung+%28Dennis%29%3BVallabhaneni%2C+Srinivas&rft.aulast=Lai&rft.aufirst=Fu-hsiung&rft.date=2008-05-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+World+Environmental+and+Water+Resources+Congress&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/EWRI08_FINALProgramComplete4-23-08.p df LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Variations in High-Intensity Precipitation under Climate Changes in the LMRB and Implications for Drinking Water Supply Security T2 - 2008 World Environmental and Water Resources Congress AN - 40967632; 4871291 JF - 2008 World Environmental and Water Resources Congress AU - Yang, Y Jeffrey AU - Haught, Roy C AU - Neal, Jill AU - Lee, Joo-Youp AU - Keener, Tim Y1 - 2008/05/13/ PY - 2008 DA - 2008 May 13 KW - Rainfall KW - Security KW - Drinking water KW - Precipitation KW - Water supplies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40967632?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+World+Environmental+and+Water+Resources+Congress&rft.atitle=Variations+in+High-Intensity+Precipitation+under+Climate+Changes+in+the+LMRB+and+Implications+for+Drinking+Water+Supply+Security&rft.au=Yang%2C+Y+Jeffrey%3BHaught%2C+Roy+C%3BNeal%2C+Jill%3BLee%2C+Joo-Youp%3BKeener%2C+Tim&rft.aulast=Yang&rft.aufirst=Y&rft.date=2008-05-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+World+Environmental+and+Water+Resources+Congress&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/EWRI08_FINALProgramComplete4-23-08.p df LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of Glass Bead and Multimedia Filtration for Turbidity and Microbial Pathogen Removal T2 - 2008 World Environmental and Water Resources Congress AN - 40967337; 4871342 JF - 2008 World Environmental and Water Resources Congress AU - Patterson, Craig L AU - Haught, Roy C AU - Bromley, David AU - Muhammad, Nur AU - Sinha, Rajib Y1 - 2008/05/13/ PY - 2008 DA - 2008 May 13 KW - Turbidity KW - Pathogens KW - Filtration KW - Glass beads UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40967337?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+World+Environmental+and+Water+Resources+Congress&rft.atitle=Comparison+of+Glass+Bead+and+Multimedia+Filtration+for+Turbidity+and+Microbial+Pathogen+Removal&rft.au=Patterson%2C+Craig+L%3BHaught%2C+Roy+C%3BBromley%2C+David%3BMuhammad%2C+Nur%3BSinha%2C+Rajib&rft.aulast=Patterson&rft.aufirst=Craig&rft.date=2008-05-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+World+Environmental+and+Water+Resources+Congress&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/EWRI08_FINALProgramComplete4-23-08.p df LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - EPAs Ongoing Green Infrastructure Research T2 - 2008 World Environmental and Water Resources Congress AN - 40960694; 4871720 JF - 2008 World Environmental and Water Resources Congress AU - Borst, Michael AU - OConnor, Thomas Patrick AU - Selvakumar, Ariamalar Y1 - 2008/05/13/ PY - 2008 DA - 2008 May 13 KW - EPA KW - Infrastructure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40960694?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+World+Environmental+and+Water+Resources+Congress&rft.atitle=EPAs+Ongoing+Green+Infrastructure+Research&rft.au=Borst%2C+Michael%3BOConnor%2C+Thomas+Patrick%3BSelvakumar%2C+Ariamalar&rft.aulast=Borst&rft.aufirst=Michael&rft.date=2008-05-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+World+Environmental+and+Water+Resources+Congress&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/EWRI08_FINALProgramComplete4-23-08.p df LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Chlorine Decay and DBP Formation under different Flow Regions in PVC and Ductile Iron Pipes: Preliminary Results on the Role of Flow Velocity and Radial Mass Transfer T2 - 2008 World Environmental and Water Resources Congress AN - 40953484; 4871601 JF - 2008 World Environmental and Water Resources Congress AU - Yang, Y Jeffrey AU - Haught, Roy C AU - Impellitteri, Christopher A AU - Clark, Robert M AU - Schupp, Don AU - Panguluri, Srinivas AU - Krishnan, Radha Y1 - 2008/05/13/ PY - 2008 DA - 2008 May 13 KW - Pipes KW - Decay KW - Iron KW - Chlorine KW - Velocity KW - Mass transfer UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40953484?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+World+Environmental+and+Water+Resources+Congress&rft.atitle=Chlorine+Decay+and+DBP+Formation+under+different+Flow+Regions+in+PVC+and+Ductile+Iron+Pipes%3A+Preliminary+Results+on+the+Role+of+Flow+Velocity+and+Radial+Mass+Transfer&rft.au=Yang%2C+Y+Jeffrey%3BHaught%2C+Roy+C%3BImpellitteri%2C+Christopher+A%3BClark%2C+Robert+M%3BSchupp%2C+Don%3BPanguluri%2C+Srinivas%3BKrishnan%2C+Radha&rft.aulast=Yang&rft.aufirst=Y&rft.date=2008-05-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+World+Environmental+and+Water+Resources+Congress&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/EWRI08_FINALProgramComplete4-23-08.p df LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Energy Efficient Recovery and Dehydration of Ethanol from Fermentation Broths by Membrane Assisted Vapor Stripping Technology T2 - 30th Symposium on Biotechnology for Fuels and Chemicals AN - 41012988; 4889410 JF - 30th Symposium on Biotechnology for Fuels and Chemicals AU - Vane, L M AU - Alvarez, F R AU - Huang, I AU - Baker, R W Y1 - 2008/05/04/ PY - 2008 DA - 2008 May 04 KW - Ethanol KW - Fermentation KW - Vapors KW - Membranes KW - Technology KW - Energy efficiency KW - Dehydration UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41012988?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=30th+Symposium+on+Biotechnology+for+Fuels+and+Chemicals&rft.atitle=Energy+Efficient+Recovery+and+Dehydration+of+Ethanol+from+Fermentation+Broths+by+Membrane+Assisted+Vapor+Stripping+Technology&rft.au=Vane%2C+L+M%3BAlvarez%2C+F+R%3BHuang%2C+I%3BBaker%2C+R+W&rft.aulast=Vane&rft.aufirst=L&rft.date=2008-05-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=30th+Symposium+on+Biotechnology+for+Fuels+and+Chemicals&rft.issn=&rft_id=info:doi/ L2 - http://www.simhq.org/meetings/30symp/30SympProgramFront.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dispersant Effectiveness as a Function of Energy Dissipation Rate in an Experimental Wave Tank T2 - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AN - 40910644; 4843601 JF - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AU - Venosa, Albert D AU - Lee, Kenneth AU - Boufadel, Michel AU - Li, Zhengkai AU - Kepkay, Paul AU - King, Thomas Y1 - 2008/05/04/ PY - 2008 DA - 2008 May 04 KW - Energy dissipation KW - Dispersants KW - Waves KW - Wave tanks KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40910644?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.atitle=Dispersant+Effectiveness+as+a+Function+of+Energy+Dissipation+Rate+in+an+Experimental+Wave+Tank&rft.au=Venosa%2C+Albert+D%3BLee%2C+Kenneth%3BBoufadel%2C+Michel%3BLi%2C+Zhengkai%3BKepkay%2C+Paul%3BKing%2C+Thomas&rft.aulast=Venosa&rft.aufirst=Albert&rft.date=2008-05-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iosc.org/docs/2008_IOSC_Final_program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Flexibility on U.S. EPA Oil Spill Prevention Measures to Accommodate Small Capacity Multisector Stakeholders T2 - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AN - 40910530; 4843529 JF - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AU - Fleming, Patricia Y1 - 2008/05/04/ PY - 2008 DA - 2008 May 04 KW - USA KW - Stakeholders KW - Prevention KW - EPA KW - Oil spills KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40910530?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.atitle=Flexibility+on+U.S.+EPA+Oil+Spill+Prevention+Measures+to+Accommodate+Small+Capacity+Multisector+Stakeholders&rft.au=Fleming%2C+Patricia&rft.aulast=Fleming&rft.aufirst=Patricia&rft.date=2008-05-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iosc.org/docs/2008_IOSC_Final_program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Summary of the Literature on the Use of Commercial Bioremediation Agents for Cleanup of Oil-Contaminated Environments T2 - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AN - 40909776; 4843680 JF - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AU - Nichols, William J AU - Scientist, Environmental AU - Zhu, Xueqing Y1 - 2008/05/04/ PY - 2008 DA - 2008 May 04 KW - Bioremediation KW - Pollution control KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40909776?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.atitle=Summary+of+the+Literature+on+the+Use+of+Commercial+Bioremediation+Agents+for+Cleanup+of+Oil-Contaminated+Environments&rft.au=Nichols%2C+William+J%3BScientist%2C+Environmental%3BZhu%2C+Xueqing&rft.aulast=Nichols&rft.aufirst=William&rft.date=2008-05-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iosc.org/docs/2008_IOSC_Final_program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - How to List a New Product on the National Oil and Hazardous Pollution, Subpart J Product Schedule T2 - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AN - 40909456; 4843579 JF - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AU - DeHaven, Leigh AU - Tirrell, Rebecca Y1 - 2008/05/04/ PY - 2008 DA - 2008 May 04 KW - Oil pollution KW - Oil spills KW - Pollution KW - New products KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40909456?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.atitle=How+to+List+a+New+Product+on+the+National+Oil+and+Hazardous+Pollution%2C+Subpart+J+Product+Schedule&rft.au=DeHaven%2C+Leigh%3BTirrell%2C+Rebecca&rft.aulast=DeHaven&rft.aufirst=Leigh&rft.date=2008-05-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iosc.org/docs/2008_IOSC_Final_program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Review of Oil Spill Incidents Reported to the National Response Center from Onshore Oil Production Facilities T2 - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AN - 40908011; 4843564 JF - 20th Triennial International Oil Spill Conference on Prevention, Preparedness, Response and Restoration (IOSC 2008) AU - Howard, Mark Y1 - 2008/05/04/ PY - 2008 DA - 2008 May 04 KW - Reviews KW - Oil spills KW - Oil production KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40908011?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.atitle=Review+of+Oil+Spill+Incidents+Reported+to+the+National+Response+Center+from+Onshore+Oil+Production+Facilities&rft.au=Howard%2C+Mark&rft.aulast=Howard&rft.aufirst=Mark&rft.date=2008-05-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=20th+Triennial+International+Oil+Spill+Conference+on+Prevention%2C+Preparedness%2C+Response+and+Restoration+%28IOSC+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iosc.org/docs/2008_IOSC_Final_program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Developmental neurotoxicity testing in vitro: models for assessing chemical effects on neurite outgrowth. AN - 71651596; 18403021 AB - In vitro models may be useful for the rapid toxicological screening of large numbers of chemicals for their potential to produce toxicity. Such screening could facilitate prioritization of resources needed for in vivo toxicity testing towards those chemicals most likely to result in adverse health effects. Cell cultures derived from nervous system tissue have proven to be powerful tools for elucidating cellular and molecular mechanisms of nervous system development and function, and have been used to understand the mechanism of action of neurotoxic chemicals. Recently, it has been suggested that in vitro models could be used to screen for chemical effects on critical cellular events of neurodevelopment, including differentiation and neurite growth. This review examines the use of neuronal cell cultures as an in vitro model of neurite outgrowth. Examples of the cell culture systems that are commonly used to examine the effects of chemicals on neurite outgrowth are provided, along with a description of the methods used to quantify this neurodevelopmental process in vitro. Issues relating to the relevance of the methods and models currently used to assess neurite outgrowth are discussed in the context of hazard identification and chemical screening. To demonstrate the utility of in vitro models of neurite outgrowth for the evaluation of large numbers of chemicals, efforts should be made to: (1) develop a set of reference chemicals that can be used as positive and negative controls for comparing neurite outgrowth between model systems, (2) focus on cell cultures of human origin, with emphasis on the emerging area of neural progenitor cells, and (3) use high-throughput methods to quantify endpoints of neurite outgrowth. JF - Neurotoxicology AU - Radio, Nicholas M AU - Mundy, William R AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protections Agency (USEPA), B105-06 Research Triangle Park, NC 27711, USA. Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 361 EP - 376 VL - 29 IS - 3 SN - 0161-813X, 0161-813X KW - Index Medicus KW - Stem Cells -- drug effects KW - Cells, Cultured KW - Humans KW - Stem Cells -- ultrastructure KW - Cell Line KW - Neurites -- ultrastructure KW - Neurites -- drug effects KW - Neurites -- pathology KW - Neurotoxicity Syndromes -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71651596?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Developmental+neurotoxicity+testing+in+vitro%3A+models+for+assessing+chemical+effects+on+neurite+outgrowth.&rft.au=Radio%2C+Nicholas+M%3BMundy%2C+William+R&rft.aulast=Radio&rft.aufirst=Nicholas&rft.date=2008-05-01&rft.volume=29&rft.issue=3&rft.spage=361&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/10.1016%2Fj.neuro.2008.02.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-25 N1 - Date created - 2008-06-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.neuro.2008.02.011 ER - TY - JOUR T1 - Temporal variation in the estrogenicity of a sewage treatment plant effluent and its biological significance. AN - 71638498; 18522128 AB - Daily variation in the estrogenic activity of effluent released by a modern sewage treatment plant (STP) was measured and its effects on the physiology, behavior, and reproductive success of male fish were evaluated. As measured by an estrogen receptor binding assay, the daily estrogenic activity of this effluent was both high and extremely variable (42 +/- 25.4 [mean +/- SD] ng 17beta-estradiol (E2) equivalents/L; n = 18). Liver VTG mRNA expression in male fathead minnows (FHM) covaried with the binding assay estimates, suggesting that these fluctuations are biologically relevant. Tests which exposed male FHMs to either fluctuating levels of E2, a constant concentration of E2 (time-weighted to reflect average concentrations), or control (no E2) demonstrated that while the estrogenic activity of this effluent was detrimental to male spawning success, the fact that its concentration varied in a daily manner was without additional influence. The variability of the effluent's estrogenicity suggests that studies concerned with the effects of STP effluents should collect multiple daily samples and then test them on an appropriate time-weighted basis. JF - Environmental science & technology AU - Martinović, Dalma AU - Denny, Jeffrey S AU - Schmieder, Patricia K AU - Ankley, Gerald T AU - Sorensen, Peter W AD - Department of Fisheries, Wildlife, and Conservation Biology, 1980 Folwell Avenue, University of Minnesota, St. Paul, Minnesota 55108, USA. martinovic.dalma@epa.gov Y1 - 2008/05/01/ PY - 2008 DA - 2008 May 01 SP - 3421 EP - 3427 VL - 42 IS - 9 SN - 0013-936X, 0013-936X KW - Estrogens KW - 0 KW - Industrial Waste KW - RNA, Messenger KW - Receptors, Estrogen KW - Sewage KW - Vitellogenins KW - Water Pollutants, Chemical KW - Index Medicus KW - Vitellogenins -- chemistry KW - Animals KW - RNA, Messenger -- metabolism KW - Water Pollutants, Chemical -- analysis KW - Cyprinidae KW - Fishes KW - Receptors, Estrogen -- metabolism KW - Time Factors KW - Protein Binding KW - Male KW - Estrogens -- metabolism KW - Waste Disposal, Fluid -- methods KW - Water Purification -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71638498?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Temporal+variation+in+the+estrogenicity+of+a+sewage+treatment+plant+effluent+and+its+biological+significance.&rft.au=Martinovi%C4%87%2C+Dalma%3BDenny%2C+Jeffrey+S%3BSchmieder%2C+Patricia+K%3BAnkley%2C+Gerald+T%3BSorensen%2C+Peter+W&rft.aulast=Martinovi%C4%87&rft.aufirst=Dalma&rft.date=2008-05-01&rft.volume=42&rft.issue=9&rft.spage=3421&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-22 N1 - Date created - 2008-06-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Primary and secondary contributions to ambient PM in the midwestern United States. AN - 71638471; 18522110 AB - Ambient PM2.5 samples were collected in five midwestern United States cities throughout 2004: East St. Louis, Illinois; Detroit Michigan; Cincinnati, Ohio; Bondville, Illinois; and Northbrook, Illinois. Monthly composites were analyzed using chemical derivatization coupled with GC-MS analysis to estimate the contributions of several sources to the total ambient organic carbon. A chemical mass balance (CMB) approach was used to estimate contributions from several primary sources. An additional, organic tracer-based technique was employed to estimate secondary contributions, including secondary organic carbon derived from isoprene, alpha-pinene, beta-caryophyllene, and toluene. The sum of these contributions was compared with the total organic carbon measured at each sampling site, and reasonable carbon mass balances were observed for four of the five sites. In Bondville, Northbrook, Cincinnati, and Detroit a strong correlation was observed between the sum of the estimated primary and secondary contributions and the measured organic carbon (R2 = 0.73). The estimated secondary organic carbon concentrations were observed to vary considerably with season, with the strongest contributions coming from isoprene and alpha-pinene during the summer. While further research is required, there is some evidence that the contribution estimates for alpha-pinene, beta-caryophyllene, and toluene SOC may to some degree represent the contributions from the broader classes of monoterpenes, sesquiterpenes, and aromatics. JF - Environmental science & technology AU - Lewandowski, Michael AU - Jaoui, Mohammed AU - Offenberg, John H AU - Kleindienst, Tadeusz E AU - Edney, Edward O AU - Sheesley, Rebecca J AU - Schauer, James J AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. lewandowski.michael@epa.gov Y1 - 2008/05/01/ PY - 2008 DA - 2008 May 01 SP - 3303 EP - 3309 VL - 42 IS - 9 SN - 0013-936X, 0013-936X KW - Air Pollutants KW - 0 KW - Organic Chemicals KW - Particulate Matter KW - Carbon KW - 7440-44-0 KW - Index Medicus KW - Air Pollution KW - Gas Chromatography-Mass Spectrometry -- methods KW - Particle Size KW - Seasons KW - Organic Chemicals -- analysis KW - Models, Statistical KW - Midwestern United States KW - Carbon -- analysis KW - Carbon -- chemistry KW - Time Factors KW - Environmental Monitoring -- methods KW - Models, Theoretical KW - Air Pollutants -- analysis KW - Particulate Matter -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71638471?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Primary+and+secondary+contributions+to+ambient+PM+in+the+midwestern+United+States.&rft.au=Lewandowski%2C+Michael%3BJaoui%2C+Mohammed%3BOffenberg%2C+John+H%3BKleindienst%2C+Tadeusz+E%3BEdney%2C+Edward+O%3BSheesley%2C+Rebecca+J%3BSchauer%2C+James+J&rft.aulast=Lewandowski&rft.aufirst=Michael&rft.date=2008-05-01&rft.volume=42&rft.issue=9&rft.spage=3303&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-22 N1 - Date created - 2008-06-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Development of species sensitivity distributions for wildlife using interspecies toxicity correlation models. AN - 71632980; 18522132 AB - Species sensitivity distributions (SSD) are probability distributions of chemical toxicity of multiple species and have had limited application in wildlife risk assessment because of relatively small data sets of wildlife toxicity values. Interspecies correlation estimation (ICE) models predict the acute toxicity to untested taxa from known toxicity of a single surrogate species. ICE models were used to predict toxicity values to wildlife species and generate SSDs for 23 chemicals using four avian surrogates. The hazard levels associated with the fifth percentile of the distribution (HD5) were compared for ICE SSDs and independent SSDs created with measured data. SSDs were composed of either avian only or avian and mammalian taxa. ICE HD5s were within 5-fold of 90% of measured HD5s and were generally higher than measured HD5s. The first percentile of the distribution (HD1) and the fifth percentile of the lower confidence limit (HDL) of ICE SSDs produced values that were not significantly different from measured HD5s. Using a bird surrogate to predicttoxicity to birds and the Norway rat to predict toxicity to mammals improved some estimates of ICE HD5s compared with those generated using only bird surrogates. These results indicate that ICE models can be used to generate SSDs comparable to those derived from measured wildlife toxicity data and provide robust estimates of the HD5. JF - Environmental science & technology AU - Awkerman, Jill A AU - Raimondo, Sandy AU - Barron, Mace G AD - U.S. Environmental Protection Agency, Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, Florida 32561, USA. awkerman.jill@epa.gov Y1 - 2008/05/01/ PY - 2008 DA - 2008 May 01 SP - 3447 EP - 3452 VL - 42 IS - 9 SN - 0013-936X, 0013-936X KW - Environmental Pollutants KW - 0 KW - Water Pollutants KW - Index Medicus KW - Sensitivity and Specificity KW - Rats KW - Ecosystem KW - Probability KW - Animals KW - Water Pollutants -- analysis KW - Databases, Factual KW - Sample Size KW - Environmental Pollutants -- analysis KW - Birds KW - Species Specificity KW - Risk Assessment KW - Models, Theoretical KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71632980?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Development+of+species+sensitivity+distributions+for+wildlife+using+interspecies+toxicity+correlation+models.&rft.au=Awkerman%2C+Jill+A%3BRaimondo%2C+Sandy%3BBarron%2C+Mace+G&rft.aulast=Awkerman&rft.aufirst=Jill&rft.date=2008-05-01&rft.volume=42&rft.issue=9&rft.spage=3447&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-22 N1 - Date created - 2008-06-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Brownfields: a local environmental health opportunity? AN - 71630786; 18517156 JF - Journal of environmental health AU - Carroll, Ann AD - Office of Brownfields & Land Revitalization, U.S. EPA, Washington, DC 20460, USA. carroll.ann@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 59 EP - 60 VL - 70 IS - 9 SN - 0022-0892, 0022-0892 KW - Hazardous Waste KW - 0 KW - Index Medicus KW - United States KW - Financing, Government KW - City Planning -- methods KW - Urban Renewal -- organization & administration KW - United States Environmental Protection Agency KW - Public Health KW - Humans KW - Urban Renewal -- methods KW - City Planning -- organization & administration KW - Environmental Pollution -- prevention & control KW - Hazardous Waste -- prevention & control KW - Environmental Health -- organization & administration KW - Community Participation KW - Environmental Health -- methods KW - Local Government UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71630786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+health&rft.atitle=Brownfields%3A+a+local+environmental+health+opportunity%3F&rft.au=Carroll%2C+Ann&rft.aulast=Carroll&rft.aufirst=Ann&rft.date=2008-05-01&rft.volume=70&rft.issue=9&rft.spage=59&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+health&rft.issn=00220892&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-23 N1 - Date created - 2008-06-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Estimating national landfill methane emissions: an application of the 2006 Intergovernmental Panel on Climate Change Waste Model in Panama. AN - 71621983; 18512440 AB - This paper estimates national methane emissions from solid waste disposal sites in Panama over the time period 1990-2020 using both the 2006 Intergovernmental Panel on Climate Change (IPCC) Waste Model spreadsheet and the default emissions estimate approach presented in the 1996 IPCC Good Practice Guidelines. The IPCC Waste Model has the ability to calculate emissions from a variety of solid waste disposal site types, taking into account country- or region-specific waste composition and climate information, and can be used with a limited amount of data. Countries with detailed data can also run the model with country-specific values. The paper discusses methane emissions from solid waste disposal; explains the differences between the two methodologies in terms of data needs, assumptions, and results; describes solid waste disposal circumstances in Panama; and presents the results of this analysis. It also demonstrates the Waste Model's ability to incorporate landfill gas recovery data and to make projections. The former default method methane emissions estimates are 25 Gg in 1994, and range from 23.1 Gg in 1990 to a projected 37.5 Gg in 2020. The Waste Model estimates are 26.7 Gg in 1994, ranging from 24.6 Gg in 1990 to 41.6 Gg in 2020. Emissions estimates for Panama produced by the new model were, on average, 8% higher than estimates produced by the former default methodology. The increased estimate can be attributed to the inclusion of all solid waste disposal in Panama (as opposed to only disposal in managed landfills), but the increase was offset somewhat by the different default factors and regional waste values between the 1996 and 2006 IPCC guidelines, and the use of the first-order decay model with a time delay for waste degradation in the IPCC Waste Model. JF - Journal of the Air & Waste Management Association (1995) AU - Weitz, Melissa AU - Coburn, Jeffrey B AU - Salinas, Edgar AD - U.S. Environmental Protection Agency, Washington, DC 20460, USA. weitz.melissa@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 636 EP - 640 VL - 58 IS - 5 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Methane KW - OP0UW79H66 KW - Index Medicus KW - Panama KW - Greenhouse Effect KW - Government Agencies KW - Algorithms KW - Forecasting KW - Conservation of Natural Resources KW - Methane -- analysis KW - Refuse Disposal -- statistics & numerical data KW - Air Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71621983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Estimating+national+landfill+methane+emissions%3A+an+application+of+the+2006+Intergovernmental+Panel+on+Climate+Change+Waste+Model+in+Panama.&rft.au=Weitz%2C+Melissa%3BCoburn%2C+Jeffrey+B%3BSalinas%2C+Edgar&rft.aulast=Weitz&rft.aufirst=Melissa&rft.date=2008-05-01&rft.volume=58&rft.issue=5&rft.spage=636&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-18 N1 - Date created - 2008-06-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of weekly exposure to anatoxin-a and nicotine on operant performance of rats. AN - 71617252; 18387783 AB - This study examined the effects of acute and weekly administration of anatoxin-a and nicotine on operant performance. Anatoxin-a is a potent nicotinic receptor agonist produced by cyanobacteria, which are found in fresh waters throughout the world. Anatoxin-a is a potential human health hazard and has been responsible for numerous deaths of wildlife, livestock and domestic animals. Remarkably little is known, however, about the effects of anatoxin-a on behavior. Nicotine, the psychomotor stimulant in tobacco, has many well-documented behavioral effects, which often diminish (i.e. tolerance develops) when it is given daily. Male Long Evans rats initially were trained to respond under a multiple variable-ratio 30-response variable-interval 60-s (mult VR-30 VI 60-s) schedule of food reinforcement. They were then divided into 12 groups of 8 that received four weekly subcutaneous injections of anatoxin-a (0.05-0.2 mg/kg), nicotine (0.125-1.8 mg/kg), or vehicle 5-min prior to testing. When initially administered, each compound decreased response rates and reinforcement rates in both components of the multiple schedule. Substantial tolerance developed to the disruptive effects of nicotine with weekly administration. Tolerance also developed to the effects of anatoxin-a, although to a lesser degree; the highest dose severely decreased performance with little evidence of recovery. In conjunction with prior findings, these results suggest the behavioral effects of anatoxin-a and nicotine are similar, but not identical, and that relatively infrequent (episodic) administration can produce tolerance. JF - Neurotoxicology and teratology AU - Jarema, K A AU - Poling, A AU - MacPhail, R C AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, U. S. Environmental Protection Agency, 109 TW Alexander Drive B105-04, Research Triangle Park, NC 27711, USA. jarema.kimberly@epa.gov PY - 2008 SP - 220 EP - 227 VL - 30 IS - 3 SN - 0892-0362, 0892-0362 KW - Nicotinic Agonists KW - 0 KW - Tropanes KW - Nicotine KW - 6M3C89ZY6R KW - anatoxin a KW - 80023A73NK KW - Index Medicus KW - Rats KW - Animals KW - Reinforcement Schedule KW - Dose-Response Relationship, Drug KW - Male KW - Conditioning, Operant -- drug effects KW - Nicotinic Agonists -- toxicity KW - Psychomotor Performance -- drug effects KW - Nicotine -- toxicity KW - Tropanes -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71617252?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+teratology&rft.atitle=Effects+of+weekly+exposure+to+anatoxin-a+and+nicotine+on+operant+performance+of+rats.&rft.au=Jarema%2C+K+A%3BPoling%2C+A%3BMacPhail%2C+R+C&rft.aulast=Jarema&rft.aufirst=K&rft.date=2008-05-01&rft.volume=30&rft.issue=3&rft.spage=220&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2008.02.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-29 N1 - Date created - 2008-05-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.ntt.2008.02.001 ER - TY - JOUR T1 - Codependencies of reactive air toxic and criteria pollutants on emission reductions. AN - 71614529; 18512446 AB - It is important to understand the effects of emission controls on concentrations of ozone, fine particulate matter (PM2.5), and hazardous air pollutants (HAPs) simultaneously, to evaluate the full range of health, ecosystem, and economic effects. Until recently, the capability to simultaneously evaluate interrelated atmospheric pollutants ("one atmosphere" analysis) was unavailable to air quality managers. In this work, we use an air quality model to examine the potential effect of three emission reductions on concentrations of ozone, PM2.5, and four important HAPs (formaldehyde, acetaldehyde, acrolein, and benzene) over a domain centered on Philadelphia for 12-day episodes in July and January 2001. Although NO(x) controls are predicted to benefit PM2.5 concentrations and sometimes benefit ozone, they have only a small effect on formaldehyde, slightly increase acetaldehyde and acrolein, and have no effect on benzene in the July episode. Concentrations of all pollutants except benzene increase slightly with NO(x) controls in the January simulation. Volatile organic compound controls alone are found to have a small effect on ozone and PM2.5, a less than linear effect on decreasing aldehydes, and an approximately linear effect on acrolein and benzene in summer, but a slightly larger than linear effect on aldehydes and acrolein in winter. These simulations indicate the difficulty in assessing how toxic air pollutants might respond to emission reductions aimed at decreasing criteria pollutants such as ozone and PM2.5. JF - Journal of the Air & Waste Management Association (1995) AU - Luecken, Deborah J AU - Cimorelli, Alan J AD - Atmospheric Modeling Division, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. luecken.deborah@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 693 EP - 701 VL - 58 IS - 5 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Oxidants, Photochemical KW - Particulate Matter KW - Ozone KW - 66H7ZZK23N KW - Acetaldehyde KW - GO1N1ZPR3B KW - Index Medicus KW - Ozone -- analysis KW - Oxidants, Photochemical -- analysis KW - Models, Statistical KW - Acetaldehyde -- analysis KW - Air Pollution -- prevention & control KW - Air Pollutants -- analysis KW - Air Pollutants -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71614529?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Codependencies+of+reactive+air+toxic+and+criteria+pollutants+on+emission+reductions.&rft.au=Luecken%2C+Deborah+J%3BCimorelli%2C+Alan+J&rft.aulast=Luecken&rft.aufirst=Deborah&rft.date=2008-05-01&rft.volume=58&rft.issue=5&rft.spage=693&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-18 N1 - Date created - 2008-06-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Computational toxicology--a state of the science mini review. AN - 70500004; 18065772 AB - Advances in computer sciences and hardware combined with equally significant developments in molecular biology and chemistry are providing toxicology with a powerful new tool box. This tool box of computational models promises to increase the efficiency and the effectiveness by which the hazards and risks of environmental chemicals are determined. Computational toxicology focuses on applying these tools across many scales, including vastly increasing the numbers of chemicals and the types of biological interactions that can be evaluated. In addition, knowledge of toxicity pathways gathered within the tool box will be directly applicable to the study of the biological responses across a range of dose levels, including those more likely to be representative of exposures to the human population. Progress in this field will facilitate the transformative shift called for in the recent report on toxicology in the 21st century by the National Research Council. This review surveys the state of the art in many areas of computational toxicology and points to several hurdles that will be important to overcome as the field moves forward. Proof-of-concept studies need to clearly demonstrate the additional predictive power gained from these tools. More researchers need to become comfortable working with both the data generating tools and the computational modeling capabilities, and regulatory authorities must show a willingness to the embrace new approaches as they gain scientific acceptance. The next few years should witness the early fruits of these efforts, but as the National Research Council indicates, the paradigm shift will take a long term investment and commitment to reach full potential. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Kavlock, Robert J AU - Ankley, Gerald AU - Blancato, Jerry AU - Breen, Michael AU - Conolly, Rory AU - Dix, David AU - Houck, Keith AU - Hubal, Elaine AU - Judson, Richard AU - Rabinowitz, James AU - Richard, Ann AU - Setzer, R Woodrow AU - Shah, Imran AU - Villeneuve, Daniel AU - Weber, Eric AD - National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. kavlock.robert@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 14 EP - 27 VL - 103 IS - 1 KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - Environmental Pollutants -- toxicity KW - Quantitative Structure-Activity Relationship KW - Models, Molecular KW - Dose-Response Relationship, Drug KW - Environmental Pollutants -- chemistry KW - Drug Design KW - Environmental Pollutants -- pharmacokinetics KW - Genomics KW - Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70500004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Computational+toxicology--a+state+of+the+science+mini+review.&rft.au=Kavlock%2C+Robert+J%3BAnkley%2C+Gerald%3BBlancato%2C+Jerry%3BBreen%2C+Michael%3BConolly%2C+Rory%3BDix%2C+David%3BHouck%2C+Keith%3BHubal%2C+Elaine%3BJudson%2C+Richard%3BRabinowitz%2C+James%3BRichard%2C+Ann%3BSetzer%2C+R+Woodrow%3BShah%2C+Imran%3BVilleneuve%2C+Daniel%3BWeber%2C+Eric&rft.aulast=Kavlock&rft.aufirst=Robert&rft.date=2008-05-01&rft.volume=103&rft.issue=1&rft.spage=14&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=1096-0929&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-08 N1 - Date created - 2008-04-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR. AN - 70488158; 18281256 AB - A number of perfluorinated alkyl acids including perfluorooctanoic acid (PFOA) elicit effects similar to peroxisome proliferator chemicals (PPC) in mouse and rat liver. There is strong evidence that PPC cause many of their effects linked to liver cancer through the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR alpha). To determine the role of PPAR alpha in mediating PFOA transcriptional events, we compared the transcript profiles of the livers of wild-type or PPAR alpha-null mice exposed to PFOA or the PPAR alpha agonist WY-14,643 (WY). After 7 days of exposure, 85% or 99.7% of the genes altered by PFOA or WY exposure, respectively were dependent on PPAR alpha. The PPAR alpha-independent genes regulated by PFOA included those involved in lipid homeostasis and xenobiotic metabolism. Many of the lipid homeostasis genes including acyl-CoA oxidase (Acox1) were also regulated by WY in a PPAR alpha-dependent manner. The increased expression of these genes in PPAR alpha-null mice may be partly due to increases in PPAR gamma expression upon PFOA exposure. Many of the identified xenobiotic metabolism genes are known to be under control of the nuclear receptor CAR (constitutive activated/androstane receptor) and the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2). There was excellent correlation between the transcript profile of PPAR alpha-independent PFOA genes and those of activators of CAR including phenobarbital and 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene (TCPOBOP) but not those regulated by the Nrf2 activator, dithiol-3-thione. These results indicate that PFOA alters most genes in wild-type mouse liver through PPAR alpha, but that a subset of genes are regulated by CAR and possibly PPAR gamma in the PPAR alpha-null mouse. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Rosen, Mitchell B AU - Lee, Janice S AU - Ren, Hongzu AU - Vallanat, Beena AU - Liu, Jie AU - Waalkes, Michael P AU - Abbott, Barbara D AU - Lau, Christopher AU - Corton, J Christopher AD - NHEERL/ORD, U.S. EPA, Research Triangle Park, North Carolina 27711, USA. Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 46 EP - 56 VL - 103 IS - 1 KW - Caprylates KW - 0 KW - Fluorocarbons KW - PPAR alpha KW - Pyrimidines KW - RNA, Messenger KW - Receptors, Cytoplasmic and Nuclear KW - Transcription Factors KW - constitutive androstane receptor KW - pirinixic acid KW - 86C4MRT55A KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Animals KW - Transcription, Genetic -- drug effects KW - Pyrimidines -- toxicity KW - Mice KW - Reverse Transcriptase Polymerase Chain Reaction KW - Mice, Knockout KW - Receptors, Cytoplasmic and Nuclear -- physiology KW - Transcription Factors -- physiology KW - Transcription Factors -- metabolism KW - Fluorocarbons -- toxicity KW - Caprylates -- toxicity KW - Liver -- metabolism KW - RNA, Messenger -- genetics KW - PPAR alpha -- genetics KW - Gene Expression Profiling KW - Liver -- drug effects KW - Receptors, Cytoplasmic and Nuclear -- metabolism KW - PPAR alpha -- metabolism KW - PPAR alpha -- physiology KW - Genomics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70488158?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Toxicogenomic+dissection+of+the+perfluorooctanoic+acid+transcript+profile+in+mouse+liver%3A+evidence+for+the+involvement+of+nuclear+receptors+PPAR+alpha+and+CAR.&rft.au=Rosen%2C+Mitchell+B%3BLee%2C+Janice+S%3BRen%2C+Hongzu%3BVallanat%2C+Beena%3BLiu%2C+Jie%3BWaalkes%2C+Michael+P%3BAbbott%2C+Barbara+D%3BLau%2C+Christopher%3BCorton%2C+J+Christopher&rft.aulast=Rosen&rft.aufirst=Mitchell&rft.date=2008-05-01&rft.volume=103&rft.issue=1&rft.spage=46&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=1096-0929&rft_id=info:doi/10.1093%2Ftoxsci%2Fkfn025 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-08 N1 - Date created - 2008-04-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/toxsci/kfn025 ER - TY - JOUR T1 - Modeling small-scale spills of aqueous solutions in the indoor environment. AN - 70428527; 17913356 AB - A mass transfer model is proposed to estimate the rates of chemical emissions from aqueous solutions spilled on hard surfaces inside buildings. The model is presented in two forms: a set of four ordinary differential equations and a simplified exact solution. The latter can be implemented in a spreadsheet. User input includes ten parameters, which represent either the properties of the source or those of the building. All of them can be readily obtained. The proposed model is tested against and in good agreement with the measurements of simulated spill events in a room-sized environmental chamber. This model can be used by emergency response planners to estimate the time history of contaminant concentrations in indoor air. JF - Journal of hazardous materials AU - Guo, Zhishi AU - Sparks, Leslie E AU - Roache, Nancy F AD - US EPA, Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, NC 27711, USA. guo.zhishi@epa.gov Y1 - 2008/05/01/ PY - 2008 DA - 2008 May 01 SP - 444 EP - 453 VL - 153 IS - 1-2 SN - 0304-3894, 0304-3894 KW - Air Pollutants KW - 0 KW - Solutions KW - Acetone KW - 1364PS73AF KW - Ammonia KW - 7664-41-7 KW - Index Medicus KW - Floors and Floorcoverings KW - Temperature KW - Volatilization KW - Disaster Planning KW - Air Pollution, Indoor -- analysis KW - Accidents KW - Ammonia -- analysis KW - Acetone -- analysis KW - Air Pollutants -- analysis KW - Models, Theoretical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70428527?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+hazardous+materials&rft.atitle=Modeling+small-scale+spills+of+aqueous+solutions+in+the+indoor+environment.&rft.au=Guo%2C+Zhishi%3BSparks%2C+Leslie+E%3BRoache%2C+Nancy+F&rft.aulast=Guo&rft.aufirst=Zhishi&rft.date=2008-05-01&rft.volume=153&rft.issue=1-2&rft.spage=444&rft.isbn=&rft.btitle=&rft.title=Journal+of+hazardous+materials&rft.issn=03043894&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-02 N1 - Date created - 2008-03-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Higher Environmental Relative Moldiness Index (ERMIsm) values measured in Detroit homes of severely asthmatic children. AN - 70381218; 18280542 AB - Sieved vacuum bag dust from the homes of 143 children in Detroit was analyzed by mold specific quantitative PCR (MSQPCR) and the Environmental Relative Moldiness Index (ERMIsm) was calculated for each home. Children living in these homes were grouped as non-asthmatic (n=83), moderately asthmatic (n=28) and severely asthmatic (n=32) based on prescription medication usage for their asthma management (none, occasional and daily, respectively). The mean ERMI for each group of homes was 6.2 for non-asthmatic, 6.3 for moderately asthmatic and 8.2 for severely asthmatic children. The ERMI values in the homes of severely asthmatic children were significantly greater compared to the non-asthmatics (p=0.04 in Wilcoxon Rank-sum test). Aspergillus niger and Aspergillus unguis were the primary mold species that distinguished severely asthmatic children's homes and non-asthmatic children's homes (p<0.05; Wilcoxon Rank-sum test). The determination of the home's ERMI values may aid in prioritizing home remediation efforts, particularly in those children who are at increased risk for asthma exacerbation. JF - The Science of the total environment AU - Vesper, Stephen AU - McKinstry, Craig AU - Haugland, Richard AU - Neas, Lucas AU - Hudgens, Edward AU - Heidenfelder, Brooke AU - Gallagher, Jane AD - National Exposure Research Laboratory (NERL), United States Environmental Protection Agency, Cincinnati, OH 45268, USA. vesper.stephen@epa.gov Y1 - 2008/05/01/ PY - 2008 DA - 2008 May 01 SP - 192 EP - 196 VL - 394 IS - 1 SN - 0048-9697, 0048-9697 KW - Air Pollutants KW - 0 KW - Dust KW - Index Medicus KW - Environmental Monitoring KW - Humans KW - Epidemiological Monitoring KW - Child KW - Michigan -- epidemiology KW - Fungi -- classification KW - Asthma -- epidemiology KW - Air Pollution, Indoor -- analysis KW - Housing KW - Dust -- analysis KW - Air Pollutants -- classification KW - Air Pollutants -- isolation & purification KW - Fungi -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70381218?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Higher+Environmental+Relative+Moldiness+Index+%28ERMIsm%29+values+measured+in+Detroit+homes+of+severely+asthmatic+children.&rft.au=Vesper%2C+Stephen%3BMcKinstry%2C+Craig%3BHaugland%2C+Richard%3BNeas%2C+Lucas%3BHudgens%2C+Edward%3BHeidenfelder%2C+Brooke%3BGallagher%2C+Jane&rft.aulast=Vesper&rft.aufirst=Stephen&rft.date=2008-05-01&rft.volume=394&rft.issue=1&rft.spage=192&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2008.01.031 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-28 N1 - Date created - 2008-03-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.scitotenv.2008.01.031 ER - TY - JOUR T1 - Computational molecular modeling for evaluating the toxicity of environmental chemicals: prioritizing bioassay requirements. AN - 69199144; 18470285 AB - The human health risk from exposure to environmental chemicals often must be evaluated when relevant elements of the preferred data are unavailable. Therefore, strategies are needed that can predict this information and prioritize the outstanding data requirements for the risk evaluation. Many modes of molecular toxicity require the chemical or one of its biotransformation products to interact with specific biologic macromolecules (i.e., proteins and DNA). Molecular modeling approaches may be adapted to study the interactions of environmental chemicals with biomolecular targets. In this commentary we provide an overview of the challenges that arise from applying molecular modeling tools developed and commonly used for pharmaceutical discovery to the problem of predicting the potential toxicities of environmental chemicals. The use of molecular modeling tools to predict the unintended health and environmental consequences of environmental chemicals differs strategically from the use of the same tools in the pharmaceutical discovery process in terms of the goals and potential applications. It also requires consideration of the greater diversity of chemical space and binding affinity domains than is covered by pharmaceuticals. Molecular modeling methods offer one of several complementary approaches to evaluate the risk to human health and the environment as a result of exposure to environmental chemicals. These tools can streamline the hazard assessment process by simulating possible modes of action and providing virtual screening tools that can help prioritize bioassay requirements. Tailoring these strategies to the particular challenges presented by environmental chemical interactions make them even more effective. JF - Environmental health perspectives AU - Rabinowitz, James R AU - Goldsmith, Michael-Rock AU - Little, Stephen B AU - Pasquinelli, Melissa A AD - National Center for Computational Toxicology, US Environmental Protection Agency, Research Triangle Park, NC, USA. Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 573 EP - 577 VL - 116 IS - 5 SN - 0091-6765, 0091-6765 KW - Hazardous Substances KW - 0 KW - Index Medicus KW - prioritizing bioassays KW - docking KW - enrichment KW - molecular modeling KW - high-throughput screening KW - false negatives KW - computational toxicology KW - virtual screening KW - Computer Simulation KW - Risk Assessment -- methods KW - Structure-Activity Relationship KW - Hazardous Substances -- adverse effects KW - Models, Molecular KW - Biological Assay KW - Hazardous Substances -- analysis KW - Hazardous Substances -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69199144?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Computational+molecular+modeling+for+evaluating+the+toxicity+of+environmental+chemicals%3A+prioritizing+bioassay+requirements.&rft.au=Rabinowitz%2C+James+R%3BGoldsmith%2C+Michael-Rock%3BLittle%2C+Stephen+B%3BPasquinelli%2C+Melissa+A&rft.aulast=Rabinowitz&rft.aufirst=James&rft.date=2008-05-01&rft.volume=116&rft.issue=5&rft.spage=573&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.11077 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-25 N1 - Date created - 2008-05-12 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Endocrinology. 1997 Sep;138(9):4022-5 [9275094] Chem Res Toxicol. 1996 Dec;9(8):1240-8 [8951225] J Comput Chem. 2005 Jul 15;26(9):915-31 [15841474] J Med Chem. 2005 Jun 16;48(12):4111-9 [15943484] Proteins. 2005 Aug 15;60(3):333-40 [15971202] Toxicol Lett. 2006 Jul 1;164(2):104-12 [16563668] Proteins. 2006 Oct 1;65(1):15-26 [16862531] BMC Struct Biol. 2006;6:19 [16995956] Curr Med Chem. 2006;13(25):2995-3003 [17073642] Toxicol Sci. 2007 Jan;95(1):5-12 [16963515] Adv Clin Chem. 2007;43:131-76 [17249383] Nat Rev Drug Discov. 2007 Mar;6(3):220-30 [17330071] Curr Opin Chem Biol. 2001 Aug;5(4):375-82 [11470599] Proteins. 2002 Jun 1;47(4):409-43 [12001221] Curr Opin Chem Biol. 2002 Aug;6(4):447-52 [12133719] Drug Discov Today. 2004 Mar 15;9(6):276-85 [15003246] Science. 2004 Mar 19;303(5665):1813-8 [15031495] Drug Discov Today. 2004 Aug 1;9(15):659-69 [15279849] Nat Biotechnol. 2004 Aug;22(8):1039-45 [15286657] Science. 1992 Aug 21;257(5073):1078-82 [1509259] Drug Metab Rev. 2005;37(1):41-213 [15747500] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1289/ehp.11077 ER - TY - JOUR T1 - Source apportionment of particulate matter in the U.S. and associations with lung inflammatory markers. AN - 69190674; 18464055 AB - Size-fractionated particulate matter (PM) samples were collected from six U.S. cities and chemically analyzed as part of the Multiple Air Pollutant Study. Particles were administered to cultured lung cells and the production of three different proinflammatory markers was measured to explore the association between the health effect markers and PM. Ultrafine, fine, and coarse PM samples were collected between December 2003 and May 2004 over a 4-wk period in each city. Filters were pooled for each city and the PM samples were extracted then analyzed for trace metals, ions, and elemental carbon. Particle extracts were applied to cultured human primary airway epithelial cells, and the secreted levels of interleukin-8 (IL-8), heme oxygenase-1, and cyclooxygenase-2 were measured 1 and 24 h following exposure. Fine PM sources were quantified by the chemical mass balance (CMB) model. The relationship between toxicological measures, PM sources, and individual species were evaluated using linear regression. Ultrafine and fine PM mass were associated with increases in IL-8 (r(2) = .80 for ultrafine and r(2) = .52 for fine). Sources of fine PM and their relative contributions varied across the sampling sites and a strong linear association was observed between IL-8 and secondary sulfate from coal combustion (r(2) = .79). Ultrafine vanadium, lead, copper, and sulfate were also associated with increases in IL-8. Increases in inflammatory markers were not observed for coarse PM mass and source markers. These findings suggest that certain PM size fractions and sources are associated with markers of lung injury or inflammation. JF - Inhalation toxicology AU - Duvall, Rachelle M AU - Norris, Gary A AU - Dailey, Lisa A AU - Burke, Janet M AU - McGee, John K AU - Gilmour, M Ian AU - Gordon, Terry AU - Devlin, Robert B AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. duvall.rachelle@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 671 EP - 683 VL - 20 IS - 7 KW - Air Pollutants KW - 0 KW - Biomarkers KW - Interleukin-8 KW - Metals KW - Nitrates KW - Particulate Matter KW - RNA, Messenger KW - Sulfates KW - Heme Oxygenase-1 KW - EC 1.14.14.18 KW - Cyclooxygenase 2 KW - EC 1.14.99.1 KW - Index Medicus KW - United States KW - Sulfates -- analysis KW - Humans KW - Particle Size KW - Lung -- cytology KW - Metals -- analysis KW - Cities KW - RNA, Messenger -- metabolism KW - Cells, Cultured KW - Nitrates -- toxicity KW - Sulfates -- toxicity KW - Biomarkers -- metabolism KW - Inflammation -- metabolism KW - Nitrates -- analysis KW - Metals -- toxicity KW - Particulate Matter -- toxicity KW - Epithelial Cells -- metabolism KW - Epithelial Cells -- drug effects KW - Cyclooxygenase 2 -- genetics KW - Interleukin-8 -- genetics KW - Heme Oxygenase-1 -- genetics KW - Air Pollutants -- analysis KW - Particulate Matter -- analysis KW - Air Pollutants -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69190674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inhalation+toxicology&rft.atitle=Source+apportionment+of+particulate+matter+in+the+U.S.+and+associations+with+lung+inflammatory+markers.&rft.au=Duvall%2C+Rachelle+M%3BNorris%2C+Gary+A%3BDailey%2C+Lisa+A%3BBurke%2C+Janet+M%3BMcGee%2C+John+K%3BGilmour%2C+M+Ian%3BGordon%2C+Terry%3BDevlin%2C+Robert+B&rft.aulast=Duvall&rft.aufirst=Rachelle&rft.date=2008-05-01&rft.volume=20&rft.issue=7&rft.spage=671&rft.isbn=&rft.btitle=&rft.title=Inhalation+toxicology&rft.issn=1091-7691&rft_id=info:doi/10.1080%2F08958370801935117 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-29 N1 - Date created - 2008-05-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/08958370801935117 ER - TY - JOUR T1 - An enzyme-linked immunosorbent assay for the determination of dioxins in contaminated sediment and soil samples. AN - 69157067; 18313102 AB - A 96-microwell enzyme-linked immunosorbent assay (ELISA) method was evaluated to determine PCDDs/PCDFs in sediment and soil samples from an EPA Superfund site. Samples were prepared and analyzed by both the ELISA and a gas chromatography/high resolution mass spectrometry (GC/HRMS) method. Comparable method precision, accuracy, and detection level (8 ng kg(-1)) were achieved by the ELISA method with respect to GC/HRMS. However, the extraction and cleanup method developed for the ELISA requires refinement for the soil type that yielded a waxy residue after sample processing. Four types of statistical analyses (Pearson correlation coefficient, paired t-test, nonparametric tests, and McNemar's test of association) were performed to determine whether the two methods produced statistically different results. The log-transformed ELISA-derived 2,3,7,8-tetrachlorodibenzo-p-dioxin values and log-transformed GC/HRMS-derived TEQ values were significantly correlated (r=0.79) at the 0.05 level. The median difference in values between ELISA and GC/HRMS was not significant at the 0.05 level. Low false negative and false positive rates (<10%) were observed for the ELISA when compared to the GC/HRMS at 1,000 ng TEQ kg(-1). The findings suggest that immunochemical technology could be a complementary monitoring tool for determining concentrations at the 1,000 ng TEQ kg(-1) action level for contaminated sediment and soil. The ELISA could also be used in an analytical triage approach to screen and rank samples prior to instrumental analysis. JF - Chemosphere AU - Emon, Jeanette M Van AU - Chuang, Jane C AU - Lordo, Robert A AU - Schrock, Mary E AU - Nichkova, Mikaela AU - Gee, Shirley J AU - Hammock, Bruce D AD - US Environmental Protection Agency, National Exposure Research Laboratory, P.O. Box 93478, Las Vegas, NV 89193-3478, USA. VanEmon.Jeanette@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 95 EP - 103 VL - 72 IS - 1 SN - 0045-6535, 0045-6535 KW - Dioxins KW - 0 KW - Soil Pollutants KW - Index Medicus KW - Gas Chromatography-Mass Spectrometry KW - Geologic Sediments -- chemistry KW - Enzyme-Linked Immunosorbent Assay -- methods KW - Dioxins -- analysis KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69157067?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=An+enzyme-linked+immunosorbent+assay+for+the+determination+of+dioxins+in+contaminated+sediment+and+soil+samples.&rft.au=Emon%2C+Jeanette+M+Van%3BChuang%2C+Jane+C%3BLordo%2C+Robert+A%3BSchrock%2C+Mary+E%3BNichkova%2C+Mikaela%3BGee%2C+Shirley+J%3BHammock%2C+Bruce+D&rft.aulast=Emon&rft.aufirst=Jeanette+M&rft.date=2008-05-01&rft.volume=72&rft.issue=1&rft.spage=95&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2008.01.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-05 N1 - Date created - 2008-04-30 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Environ Sci Technol. 2002 Sep 1;36(17):3700-5 [12322740] Anal Chem. 2004 Apr 1;76(7):1948-56 [15053656] Toxicol Sci. 2006 Oct;93(2):223-41 [16829543] Chemosphere. 2007 Jan;66(2):234-42 [16860850] Chemosphere. 2007 Apr;67(9):S344-9 [17223171] Toxicology. 1987 Sep;45(3):229-43 [3629609] Anal Chem. 1998 Mar 15;70(6):1092-9 [9530001] J Anim Sci. 1998 Jan;76(1):134-41 [9464894] Environ Health Perspect. 2002 Jul;110(7):625-8 [12117637] Chemosphere. 2002 Mar;46(9-10):1471-6 [12002478] J AOAC Int. 2001 Jan-Feb;84(1):125-33 [11234798] Toxicol Ind Health. 1997 Nov-Dec;13(6):759-68 [9399421] Environ Health Perspect. 1998 Dec;106(12):775-92 [9831538] Anal Bioanal Chem. 2006 May;385(2):357-66 [16598456] Anal Bioanal Chem. 2006 Jun;385(4):742-52 [16741774] Anal Chem. 2007 Apr 1;79(7):2945-51 [17343366] Chemosphere. 2007 Apr;67(9):S96-108 [17258267] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.chemosphere.2008.01.012 ER - TY - JOUR T1 - Verification of dioxin formation in a catalytic oxidizer. AN - 69157054; 18334262 AB - Emissions and inlet concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDF) have been measured from a catalytic oxidizer and a thermal oxidizer. The catalyst inlet temperature was 427 degrees C. The thermal oxidizer operating temperature was 791 degrees C. Data of the toxic dioxin and furan congeners are reported. Important results of this field study are: (1) the catalytic oxidizer in this study produced an increase in PCDD/PCDF congener concentration of almost 10-fold from the inlet to the outlet (stack), thus verifying results of a previous study that evaluated only PCDD/PCDF emissions. All congeners increased from inlet to the stack. (2) The thermal oxidizer had little effect on PCDD/PCDF levels. There was a decrease in four of the congeners and an increase in 13 congeners. (3) Ambient air was the main source of PCDD/PCDFs in the stack emissions of the thermal oxidizer in this study. Laboratory investigations are needed to understand how PCDD/PCDFs are formed (and emitted) under conditions of this study. JF - Chemosphere AU - Hart, John R AD - California EPA, Department of Toxic Substances Control, P.O. Box 806, Sacramento, CA 95812-0806, USA. jhart1@dtsc.ca.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 75 EP - 78 VL - 72 IS - 1 SN - 0045-6535, 0045-6535 KW - Benzofurans KW - 0 KW - Polychlorinated Dibenzodioxins KW - Polymers KW - polychlorodibenzofuran KW - Index Medicus KW - Oxidation-Reduction KW - Catalysis KW - Polychlorinated Dibenzodioxins -- analogs & derivatives KW - Polychlorinated Dibenzodioxins -- chemistry KW - Polymers -- chemistry KW - Benzofurans -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69157054?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Verification+of+dioxin+formation+in+a+catalytic+oxidizer.&rft.au=Hart%2C+John+R&rft.aulast=Hart&rft.aufirst=John&rft.date=2008-05-01&rft.volume=72&rft.issue=1&rft.spage=75&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2008.01.058 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-05 N1 - Date created - 2008-04-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.chemosphere.2008.01.058 ER - TY - JOUR T1 - Methylmercury and omega-3 fatty acids: co-occurrence of dietary sources with emphasis on fish and shellfish. AN - 69119082; 17996230 AB - Despite many claims of broad benefits, especially for in utero development, derived from the consumption of fish as a source of omega-3 fatty acids, individual species of fish and shellfish provide substantially varied levels of these fatty acids. Likewise, mean methylmercury (MeHg) concentrations for fish and shellfish species differ by greater than an order of magnitude. Consideration of within-species variability would increase this variation farther. Exposures to both MeHg and to the omega-3 fatty acids reflect dietary choices including species consumed, frequency of consumption, and portion size. In view of these sources of variability, data on dietary patterns and blood mercury (microg/L) among women of child-bearing age (e.g., 16-49 years) provided an indication of exposures in the United States. Utilizing data from the National Health and Nutrition Examination Survey (NHANES) for survey years 1999--2002, calculated consumption of MeHg and omega-3 fatty acids from fish and shellfish have been estimated based on results from 3614 women who provided 30-day dietary recall and 24-hours records. Statistics from NHANES when appropriately weighted are representative of the US population. The association between dietary MeHg from fish and shellfish and dietary fish intake yielded a Pearson correlation of 0.68. The Pearson correlation between estimated 30-day intake from fish/shellfish consumption for omega-3 fatty acids and MeHg was 0.66. Evaluation of the most commonly consumed fish and shellfish species as sources of MeHg and omega-3 fatty acids indicated that salmon followed by shrimp are principal sources of omega-3 fatty acids and are lesser sources of MeHg, in contrast with tuna which provides omega-3 fatty acids, but considerably higher levels of MeHg. These data can be used to guide selection of individual fish and shellfish species that are higher in omega-3 content and low in MeHg concentrations. This more refined dietary approach contrasts with generic recommendations that simply advise increasing fish consumption as a path toward improving cardiovascular health and providing benefits for in utero development or avoiding fish altogether. JF - Environmental research AU - Mahaffey, Kathryn R AU - Clickner, Robert P AU - Jeffries, Rebecca A AD - United States Environmental Protection Agency, 1200 Pennsylvania Ave, NW, Washington, DC 20460, USA. mahaffey.kate@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 20 EP - 29 VL - 107 IS - 1 SN - 0013-9351, 0013-9351 KW - Fatty Acids, Omega-3 KW - 0 KW - Methylmercury Compounds KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - Diet Records KW - Environmental Exposure -- statistics & numerical data KW - Humans KW - Adult KW - Middle Aged KW - Adolescent KW - Female KW - Mercury -- blood KW - Seafood -- adverse effects KW - Seafood -- statistics & numerical data KW - Methylmercury Compounds -- administration & dosage KW - Fatty Acids, Omega-3 -- administration & dosage KW - Diet -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69119082?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+research&rft.atitle=Methylmercury+and+omega-3+fatty+acids%3A+co-occurrence+of+dietary+sources+with+emphasis+on+fish+and+shellfish.&rft.au=Mahaffey%2C+Kathryn+R%3BClickner%2C+Robert+P%3BJeffries%2C+Rebecca+A&rft.aulast=Mahaffey&rft.aufirst=Kathryn&rft.date=2008-05-01&rft.volume=107&rft.issue=1&rft.spage=20&rft.isbn=&rft.btitle=&rft.title=Environmental+research&rft.issn=00139351&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-22 N1 - Date created - 2008-04-18 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Environ Res. 2009 Jan;109(1):131-2; discussion 133-4 [19027108] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - High sensitivity of children to swimming-associated gastrointestinal illness: results using a rapid assay of recreational water quality. AN - 69112948; 18379427 AB - Culture-based methods of monitoring fecal pollution in recreational waters require 24 to 48 hours to obtain results. This delay leads to potentially inaccurate management decisions regarding beach safety. We evaluated the quantitative polymerase chain reaction (QPCR) as a faster method to assess recreational water quality and predict swimming-associated illnesses. We enrolled visitors at 4 freshwater Great Lakes beaches, and contacted them 10 to 12 days later to ask about health symptoms experienced since the visit. Water at the beaches was polluted by point sources that carried treated sewage. We tested water samples daily for Enterococcus using QPCR and membrane filtration (EPA Method 1600). We completed 21,015 interviews and tested 1359 water samples. Enterococcus QPCR cell equivalents (CEs) were positively associated with swimming-associated gastrointestinal (GI) illness (adjusted odds ratio per 1 log10 QPCR CE =1.26; 95% confidence interval = 1.06-1.51). The association between GI illness and QPCR CE was stronger among children aged 10 years and below (1.69; 1.24-2.30). Nonenteric illnesses were not consistently associated with Enterococcus QPCR CE exposure, although rash and earache occurred more frequently among swimmers. Enterococcus QPCR CE exposure was more strongly associated with GI illness than Enterococcus measured by membrane filtration. Measurement of the indicator bacteria Enterococci in recreational water using a rapid QPCR method predicted swimming-associated GI illness at freshwater beaches polluted by sewage discharge. Children at 10 years or younger were at greater risk for GI illness following exposure. JF - Epidemiology (Cambridge, Mass.) AU - Wade, Timothy J AU - Calderon, Rebecca L AU - Brenner, Kristen P AU - Sams, Elizabeth AU - Beach, Michael AU - Haugland, Richard AU - Wymer, Larry AU - Dufour, Alfred P AD - US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Chapel Hill, NC 27711, USA. wade.tim@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 375 EP - 383 VL - 19 IS - 3 SN - 1044-3983, 1044-3983 KW - Index Medicus KW - Feces -- microbiology KW - Humans KW - Infant, Newborn KW - Models, Statistical KW - Child KW - Water Pollution -- adverse effects KW - Child, Preschool KW - Infant KW - Prospective Studies KW - Adult KW - Middle Aged KW - Epidemiological Monitoring KW - Adolescent KW - Environmental Monitoring -- methods KW - Female KW - Male KW - Bathing Beaches KW - Swimming KW - Enterococcus -- isolation & purification KW - Fresh Water -- microbiology KW - Polymerase Chain Reaction -- methods KW - Gastrointestinal Diseases -- microbiology KW - Water Microbiology KW - Gastrointestinal Diseases -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69112948?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+%28Cambridge%2C+Mass.%29&rft.atitle=High+sensitivity+of+children+to+swimming-associated+gastrointestinal+illness%3A+results+using+a+rapid+assay+of+recreational+water+quality.&rft.au=Wade%2C+Timothy+J%3BCalderon%2C+Rebecca+L%3BBrenner%2C+Kristen+P%3BSams%2C+Elizabeth%3BBeach%2C+Michael%3BHaugland%2C+Richard%3BWymer%2C+Larry%3BDufour%2C+Alfred+P&rft.aulast=Wade&rft.aufirst=Timothy&rft.date=2008-05-01&rft.volume=19&rft.issue=3&rft.spage=375&rft.isbn=&rft.btitle=&rft.title=Epidemiology+%28Cambridge%2C+Mass.%29&rft.issn=10443983&rft_id=info:doi/10.1097%2FEDE.0b013e318169cc87 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-31 N1 - Date created - 2008-04-17 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Epidemiology. 2009 Jan;20(1):156-7; author reply 157 [19234407] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/EDE.0b013e318169cc87 ER - TY - JOUR T1 - Net anthropogenic phosphorus inputs: spatial and temporal variability in the Chesapeake Bay region AN - 21254476; 11718834 AB - We estimated net anthropogenic phosphorus inputs (NAPI) in the Chesapeake Bay region. NAPI is an index of phosphorus pollution potential. NAPI was estimated by quantifying all phosphorus inputs and outputs for each county. Inputs include fertilizer applications and non-food phosphorus uses, while trade of food and feed can be an input or an output. The average of 1987, 1992, 1997, and 2002 NAPI for individual counties ranged from 0.02 to 78.46kgPha super(-1)year super(-1). The overall area-weighted average NAPI for 266 counties in the region was 4.52kgPha super(-1[) year super(-1), indicating a positive net phosphorus input that can accumulate in the landscape or can pollute the water. Large positive NAPI values were associated with agricultural and developed land cover. County area-weighted NAPI increased from 4.43 to 4.94kgPha super(-1)year super(-1) between 1987 and 1997 but decreased slightly to 4.86 kgPha super(-1)ye ar super(-1) by 2002. Human population density, livestock unit density, and percent row crop land combined to explain 83% of the variability in NAPI among counties. Around 10% of total NAPI entering the Chesapeake Bay watershed is discharged into Chesapeake Bay. The developed land component of NAPI had a strong direct correlation with measured phosphorus discharges from major rivers draining to the Bay (R super(2)=0.81), however, the correlation with the simple percentage of developed land was equally strong. Our results help identify the sources of P in the landscape and evaluate the utility of NAPI as a predictor of water quality. JF - Biogeochemistry AU - Russell, Marc J AU - Weller, Donald E AU - Jordan, Thomas E AU - Sigwart, Kevin J AU - Sullivan, Kathryn J AD - Smithsonian Environmental Research Center, Edgewater, MD, USA, russell.marc@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 285 EP - 304 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 88 IS - 3 SN - 0168-2563, 0168-2563 KW - Ecology Abstracts; Sustainability Science Abstracts; Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - Water Pollution KW - water quality KW - Variability KW - Marine Environment KW - Phosphorus KW - Population density KW - Anthropogenic factors KW - human population density KW - Freshwater KW - Watersheds KW - Water quality KW - Crops KW - spatial distribution KW - Fertilizers KW - Brackishwater environment KW - Cadmium KW - Pollution KW - Rivers KW - anthropogenic factors KW - Biogeochemistry KW - Temporal variations KW - Density KW - Landscape KW - Estuaries KW - River discharge KW - Brackish KW - Human Population KW - ANW, USA, Chesapeake Bay KW - Water pollution KW - Livestock KW - Fertilizer application KW - Foods KW - Fertilizer applications KW - Pollution Index KW - Feeds KW - Q5 08503:Characteristics, behavior and fate KW - D 04070:Pollution KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution KW - Q2 09181:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21254476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biogeochemistry&rft.atitle=Net+anthropogenic+phosphorus+inputs%3A+spatial+and+temporal+variability+in+the+Chesapeake+Bay+region&rft.au=Russell%2C+Marc+J%3BWeller%2C+Donald+E%3BJordan%2C+Thomas+E%3BSigwart%2C+Kevin+J%3BSullivan%2C+Kathryn+J&rft.aulast=Russell&rft.aufirst=Marc&rft.date=2008-05-01&rft.volume=88&rft.issue=3&rft.spage=285&rft.isbn=&rft.btitle=&rft.title=Biogeochemistry&rft.issn=01682563&rft_id=info:doi/10.1007%2Fs10533-008-9212-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Fertilizers; Temporal variations; Biogeochemistry; Estuaries; River discharge; Anthropogenic factors; Population density; Brackishwater environment; Water pollution; Rivers; Landscape; Fertilizer applications; Phosphorus; Water quality; Watersheds; Crops; Pollution; water quality; anthropogenic factors; human population density; Livestock; Fertilizer application; spatial distribution; Cadmium; Feeds; Water Pollution; Foods; Marine Environment; Variability; Density; Human Population; Pollution Index; ANW, USA, Chesapeake Bay; Brackish; Freshwater DO - http://dx.doi.org/10.1007/s10533-008-9212-9 ER - TY - JOUR T1 - Noise and health in the Greater Rotterdam Area AN - 21112071; 10958946 AB - In the Greater Rotterdam Area a second study to Noise and Health has been carried out in 2007 and 2008. In 2003 a first study was carried out and that study reported that around 12 percent of the people living in the Greater Rotterdam Area were highly annoyed by noise mainly caused by traffic. The number of people sleep was disturbed and suffered high blood pressure were reported and amounted to 6 percent for sleep disturbance and 3 percent were suffering hypertension. The 2003 study took place within the regularly framework of the Rotterdam Regional Council of Governments Environmental Monitoring program, a program that reports yearly the environmental performance indicators in the Greater Rotterdam Area. Beside this yearly report a theme report is published. Last year's theme reports were published about Air Quality and Energy. In 2007 the board of this program decided that in 2008 the theme should be Noise and Health. The 2008 study is not only an update of the 2003 study but is more detailed and more comprehensive as well, and based on recent insights in health effects, caused by long lasting noise too. JF - Journal of the Acoustical Society of America AU - Wolfert, H AD - DCMR EPA, P.O. Box 843, sGravelandseweg 565, 3100AV Schiedam, Netherlands, henk.wolfert@dcmr.nl Y1 - 2008/05// PY - 2008 DA - May 2008 VL - 123 IS - 5 SN - 0001-4966, 0001-4966 KW - Pollution Abstracts KW - Environmental monitoring KW - Pollution monitoring KW - disturbance KW - Noise levels KW - Netherlands, Rotterdam KW - Air quality KW - traffic KW - councils KW - hypertension KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21112071?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Acoustical+Society+of+America&rft.atitle=Noise+and+health+in+the+Greater+Rotterdam+Area&rft.au=Wolfert%2C+H&rft.aulast=Wolfert&rft.aufirst=H&rft.date=2008-05-01&rft.volume=123&rft.issue=5&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Acoustical+Society+of+America&rft.issn=00014966&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Netherlands, Rotterdam; Noise levels; Air quality; hypertension; Pollution monitoring; Environmental monitoring; disturbance; councils; traffic ER - TY - JOUR T1 - A Simple and Rapid Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry Method to Screen Fish Plasma Samples for Estrogen- Responsive Biomarkers AN - 21058869; 8188782 AB - In the present study, we describe and evaluate the performance of a simple and rapid mass spectral method for screening fish plasma for estrogen- responsive biomarkers using matrix-assisted laser desorption/ionization (MALDI) time of flight mass spectrometry coupled with a short-term fish assay. Adult male sheepshead minnows (Cyprinodon variegatus) were placed into aquaria consisting of vehicle control and the following estrogen agonist treatments: 17 beta -estradiol (0.00625, 0.0125, 0.025, 0.05, 0.1, 0.2, 0.5, and 1.0 mu g/L, 4-tert-pentylphenol (100 mu g/L), methoxychlor (6 and 12 mu g/L), and bisphenol A (100 and 1,000 mu g/L). Treatments with chlorpyrifos (80 mu g/L) and endosulfan (0.6 mu g/L) served as nonestrogenic negative controls. Test concentrations were maintained using an intermittent flow- through dosing apparatus. Plasma was obtained from individuals, diluted and applied to an inert surface, and analyzed by MALDI. Multiple protein peaks, ranging from 2.9 to 12.9 kDa, were identified as markers of estrogenic effects when comparing estrogen-treated and control fish using interpercentile reference values. A binary classification tree model was constructed from plasma protein profiles of the vehicle control and the 0.2 mu g/L of 17 beta -estradiol treatments and then used to evaluate all samples. Treatments with the estrogen agonists 17 beta -estradiol, 4-tert- pentylphenol, methoxychlor, and bisphenol-A generated reproducible diagnostic biomarkers based on the presence of specific estrogen-responsive plasma proteins. The controls and nonestrogenic compounds chlorpyrifos and endosulfan did not produce this estrogen-responsive protein profile. A no- observed-effect level for 17 beta -estradiol at 0.025 mu g/L was estimated from concentration-response exposures. The MALDI method described here provides a straightforward, sensitive, and specific tool to screen chemicals for estrogenic activity. JF - Environmental Toxicology and Chemistry AU - Salinas, Kimberly A AU - Hemmer, Michael J AU - Harris, Peggy S AU - Walker, Calvin C AD - U.S. Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Gulf Ecology Division, Gulf Breeze, Florida Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 1175 EP - 1183 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 27 IS - 5 SN - 0730-7268, 0730-7268 KW - Pollution Abstracts; Toxicology Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Endocrine-disrupting compounds KW - Protein profiling KW - Matrix-assisted laser desorption/ionization KW - Sheepshead minnow KW - Estrogen KW - Biomarkers KW - Freshwater fish KW - Mass spectroscopy KW - Sex hormones KW - Aquaria KW - Classification KW - Bioindicators KW - Endosulfan KW - Chlorpyrifos KW - Profiles KW - Methoxychlor KW - Fish KW - Lasers KW - Ionization KW - Cyprinodon variegatus KW - estrogens KW - Chemicals KW - Mass Spectrometry KW - Mass spectrometry KW - Models KW - Bisphenol A KW - Plasma proteins KW - 17 beta -Estradiol KW - Screening KW - Estrogens KW - Geochemistry KW - estrogenic activity KW - biomarkers KW - Pesticides KW - Proteins KW - X 24390:Radioactive Materials KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - Q5 08502:Methods and instruments KW - Q1 08343:Taxonomy and morphology KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21058869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=A+Simple+and+Rapid+Matrix-Assisted+Laser+Desorption%2FIonization+Time+of+Flight+Mass+Spectrometry+Method+to+Screen+Fish+Plasma+Samples+for+Estrogen-+Responsive+Biomarkers&rft.au=Salinas%2C+Kimberly+A%3BHemmer%2C+Michael+J%3BHarris%2C+Peggy+S%3BWalker%2C+Calvin+C&rft.aulast=Salinas&rft.aufirst=Kimberly&rft.date=2008-05-01&rft.volume=27&rft.issue=5&rft.spage=1175&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F07-226.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Screening; Classification; Geochemistry; Pesticides; Lasers; Biomarkers; Freshwater fish; Mass spectroscopy; Sex hormones; Estrogens; biomarkers; estrogenic activity; Endosulfan; Models; Aquaria; Plasma proteins; Chlorpyrifos; Bisphenol A; Methoxychlor; 17 beta -Estradiol; Ionization; Chemicals; Bioindicators; Mass spectrometry; Proteins; estrogens; Mass Spectrometry; Profiles; Fish; Cyprinodon variegatus DO - http://dx.doi.org/10.1897/07-226.1 ER - TY - JOUR T1 - Influence of land use and watershed characteristics on protozoa contamination in a potential drinking water resources reservoir AN - 20946350; 8294066 AB - Relative changes in the microbial quality of Lake Texoma, on the border of Texas and Oklahoma, were investigated by monitoring protozoan pathogens, fecal indicators, and factors influencing the intensity of the microbiological contamination of surface water reservoirs. The watershed serves rural agricultural communities active in cattle ranching, recreation, and is a potential drinking water source. A total of 193 surface water samples were tested over a 27-month period to determine levels of parasite contamination. The overall occurrence of Cryptosporidium oocysts was higher in both frequency and concentration than Giardia cysts. Cryptosporidium oocysts were found in 99% and Giardia cysts in 87% of the samples. Although Cryptosporidium and Giardia occurrence were significantly but not strongly correlated, all other correlation coefficients including turbidity and total dissolved solids were non-significant. Statistically supportable seasonal variations were found suggesting that Cryptosporidium and Giardia were higher in summer and fall than in other seasons of the year. While Cryptosporidium levels were correlated with rainfall, this was not the case with Giardia. The maximum numbers for both protozoan parasites were detected from a site impacted by cattle ranching during calving season. Restriction fragment length polymorphism analysis was used for confirmation of Cryptosporidium in surface waters influenced by agricultural discharges. As we had expected, oocysts were of the bovine type indicating that the Cryptosporidium parvum detected in surface waters perhaps came from cattle living in the watershed. JF - Water Research AU - Keeley, A AU - Faulkner, B R AD - US Environmental Protection Agency, 919 Kerr Research Drive, Ada, OK 74820, USA, keeley.ann@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 2803 EP - 2813 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl] VL - 42 IS - 10-11 SN - 0043-1354, 0043-1354 KW - Aqualine Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - USA, Oklahoma, Texoma L. KW - Parasites KW - Water reservoirs KW - Contamination KW - Surface water KW - Rainfall KW - Ranching KW - Surface Water KW - Watersheds KW - Calving KW - USA, Oklahoma KW - Giardia KW - Lakes KW - Reservoirs KW - Seasonal variations KW - Oocysts KW - Restriction fragment length polymorphism KW - Pathogens KW - Endoparasites KW - Cysts KW - Land use KW - Cryptosporidium parvum KW - Cattle KW - Recreation KW - Protozoa KW - Cryptosporidium KW - Microorganisms KW - USA, Texas KW - Drinking water KW - Turbidity KW - Q2 09241:General KW - SW 3060:Water treatment and distribution KW - K 03450:Ecology KW - AQ 00004:Water Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20946350?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Research&rft.atitle=Influence+of+land+use+and+watershed+characteristics+on+protozoa+contamination+in+a+potential+drinking+water+resources+reservoir&rft.au=Keeley%2C+A%3BFaulkner%2C+B+R&rft.aulast=Keeley&rft.aufirst=A&rft.date=2008-05-01&rft.volume=42&rft.issue=10-11&rft.spage=2803&rft.isbn=&rft.btitle=&rft.title=Water+Research&rft.issn=00431354&rft_id=info:doi/10.1016%2Fj.watres.2008.02.028 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Parasites; Water reservoirs; Ranching; Pathogens; Cysts; Watersheds; Endoparasites; Turbidity; Calving; Oocysts; Contamination; Surface water; Rainfall; Restriction fragment length polymorphism; Land use; Lakes; Recreation; Protozoa; Drinking water; Seasonal variations; Cattle; Giardia; Cryptosporidium; Microorganisms; Surface Water; Reservoirs; Cryptosporidium parvum; USA, Oklahoma; USA, Oklahoma, Texoma L.; USA, Texas DO - http://dx.doi.org/10.1016/j.watres.2008.02.028 ER - TY - JOUR T1 - Biomarker induction in tropical fish species on the Northwest Shelf of Australia by produced formation water AN - 20775979; 8103721 AB - Normal operation of oil well platforms results in the discharge of produced formation water (PFW). The expression of CYP1A, CYP2M1- and 2K1-like proteins was examined for use as possible biomarkers of PFW exposure. A pilot study on the Northwest Shelf of Australia had indicated that PFW contamination possibly contributes to induction of CYP1A-like proteins in Gold-Spotted Trevally (Carangoides fulvoguttatus). The pilot study samples were re-examined for CYP1A, and, in addition, CYP2K1/2M1-like proteins. In a subsequent caged fish study in the same location a second species, Stripey seaperch (Lutjanus carponotatus), caught at a clean site, were distributed to three caging sites in a PFW gradient from the Harriet A production platform: A (near-field), B (far-field) and C (a non-impacted reference site). Fish were sampled at time (T) T=0, T=3 and T=10 days. Significant increases of CYP1A, one CYP2K1- and two CYP2M1-like proteins were noted at Site A at T=10d. For another CYP2K1-like protein, a significant increase was observed at Site A only at T=3d. These results support a previous study indicating that CYP1A protein is sensitive to PFW exposure. Importantly, statistically significant environmental induction of both CYP2M1- and CYP2K1-like proteins in tropical fish due to PFW exposure had not previously been described and induction of enzymes in the CYP2 family suggest new biomarkers for PFW. In addition, the novel response of one CYP2K-like protein requires further verification, but offers promise for improved monitoring of sub-lethal responses in marine organisms. JF - Marine Environmental Research AU - Zhu, S AU - King, S C AU - Haasch, M L AD - National Center for Natural Products Research, Pharmacology Department, School of Pharmacy, The University of Mississippi, 347 Faser, University, MS 38677-1848, United States, Haasch.Mary@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 315 EP - 324 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 65 IS - 4 SN - 0141-1136, 0141-1136 KW - Pollution Abstracts; Toxicology Abstracts; Oceanic Abstracts KW - Contamination KW - Carangoides KW - Statistical analysis KW - Pollution effects KW - Biomarkers KW - Freshwater KW - Oil KW - Australia KW - Oil wells KW - Bioindicators KW - Marine KW - Lutjanus carponotatus KW - Tropical fish KW - River discharge KW - Enzymes KW - tropical fishes KW - biomarkers KW - CYP1A protein KW - Production platforms KW - Offshore structures KW - Proteins KW - Marine organisms KW - Pollution control KW - O 4080:Pollution - Control and Prevention KW - P 1000:MARINE POLLUTION KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20775979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Environmental+Research&rft.atitle=Biomarker+induction+in+tropical+fish+species+on+the+Northwest+Shelf+of+Australia+by+produced+formation+water&rft.au=Zhu%2C+S%3BKing%2C+S+C%3BHaasch%2C+M+L&rft.aulast=Zhu&rft.aufirst=S&rft.date=2008-05-01&rft.volume=65&rft.issue=4&rft.spage=315&rft.isbn=&rft.btitle=&rft.title=Marine+Environmental+Research&rft.issn=01411136&rft_id=info:doi/10.1016%2Fj.marenvres.2007.11.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Offshore structures; Production platforms; River discharge; Tropical fish; Marine organisms; Pollution effects; Biomarkers; Oil wells; Pollution control; Oil; CYP1A protein; Contamination; Statistical analysis; Enzymes; biomarkers; Bioindicators; Proteins; tropical fishes; Lutjanus carponotatus; Carangoides; Australia; Marine; Freshwater DO - http://dx.doi.org/10.1016/j.marenvres.2007.11.007 ER - TY - JOUR T1 - Characterization of the effects of inhaled perchloroethylene on sustained attention in rats performing a visual signal detection task AN - 20721523; 8258570 AB - The aliphatic hydrocarbon perchloroethylene (PCE) has been associated with neurobehavioral dysfunction including reduced attention in humans. The current study sought to assess the effects of inhaled PCE on sustained attention in rats performing a visual signal detection task (SDT). Due to its similarities in physiological effect to toluene and trichloroethylene (TCE), two other commonly used volatile organic compounds (VOCs) known to reduce attention in rats, we hypothesized (1) that acute inhalation of PCE (0, 500, 1000, 1500 ppm) would disrupt performance of the SDT in rats; (2) that impaired accuracy would result from changes in attention to the visual signal; and (3) that these acute effects would diminish upon repetition of exposure. PCE impaired performance of the sustained attention task as evidenced by reduced accuracy [P(correct): 500 to 1500 ppm], elevated response time [RT: 1000 and 1500 ppm] and reduced number of trials completed [1500 ppm]. These effects were concentration-related and either increased (RT and trial completions) or remained constant [P(correct)] across the 60-min test session. The PCE-induced reduction in accuracy was primarily due to an increase in false alarms, a pattern consistent with reduced attention to the signal. A repeat of the exposures resulted in smaller effects on these performance measures. Thus, like toluene and TCE, inhaled PCE acutely impaired sustained attention in rats, and its potency weakened upon repetition of the exposure. JF - Neurotoxicology and Teratology AU - Oshiro, WM AU - Krantz, Q T AU - Bushnell, P J AD - National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, 27711, United States, oshiro.wendy@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 167 EP - 174 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 30 IS - 3 SN - 0892-0362, 0892-0362 KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - Inhalation KW - Acute effects KW - Repetition KW - Hydrocarbons KW - Visual perception KW - Toluene KW - volatile organic compounds KW - Tetrachloroethylene KW - Trichloroethylene KW - Attention task KW - N3 11028:Neuropharmacology & toxicology KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20721523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Characterization+of+the+effects+of+inhaled+perchloroethylene+on+sustained+attention+in+rats+performing+a+visual+signal+detection+task&rft.au=Oshiro%2C+WM%3BKrantz%2C+Q+T%3BBushnell%2C+P+J&rft.aulast=Oshiro&rft.aufirst=WM&rft.date=2008-05-01&rft.volume=30&rft.issue=3&rft.spage=167&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2008.01.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Acute effects; Inhalation; Repetition; Visual perception; Hydrocarbons; Toluene; volatile organic compounds; Trichloroethylene; Tetrachloroethylene; Attention task DO - http://dx.doi.org/10.1016/j.ntt.2008.01.002 ER - TY - JOUR T1 - A modified light transmission visualization method for DNAPL saturation measurements in 2-D models AN - 20708194; 8185979 AB - In this research, a light transmission visualization (LTV) method was used to quantify dense non-aqueous phase liquids (DNAPL) saturation in two-dimensional (2-D), two fluid phase systems. The method is an expansion of earlier LTV methods and takes into account both absorption and refraction light theories. Based on this method, DNAPL and water saturations can rapidly be obtained point wise across sand-packed 2-D flow chambers without the need to develop a calibration curve. A single point calibration step is, however, needed when dyed DNAPL is used to account for the change in the transmission factor at the dyed DNAPL-water interface. The method was applied to measure, for the first time, undyed DNAPL saturation in small 2-D chambers. Known amounts of DNAPL, modeled by tetrachloroethylene (PCE), were added to the chamber and these amounts were compared to results obtained by this LTV method. Strong correlation existed between results obtained based on this method and the known PCE amounts with an R super(2) value of 0.993. Similar experiments conducted using dyed PCE showed a stronger correlation between results obtained by this LTV method and the known amounts of dyed PCE added to the chamber with an R super(2) value of 0.999. The method was also used to measure dyed PCE saturation in a large 2-D model following sparging experiments. Results obtained from image analyses following each sparging event were compared to results obtained by two independent techniques, namely gas chromatography-mass spectrometry (GC/MS) analyses and carbon column extraction. There was a good agreement between the results obtained by this LTV method and those obtained by the two independent techniques when experiments were carried out under stable light source conditions and errors in mass balance were minor. The method presented here can be expanded to measure fluid contents in three fluid phase systems and provide a non-destructive, non-intrusive tool to investigate changes in DNAPL architecture and flow characteristics in laboratory experiments. JF - Advances in Water Resources AU - Bob, M M AU - Brooks, M C AU - Mravik, S C AU - Wood, AL AD - National Risk Management Research Laboratory, Groundwater and Ecosystem Restoration Division, Subsurface Protection and Remediation Branch, 919 Kerr Research Dr., Ada, OK 74820, United States, bob.mustafa@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 727 EP - 742 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 31 IS - 5 SN - 0309-1708, 0309-1708 KW - Water Resources Abstracts; Aqualine Abstracts; Meteorological & Geoastrophysical Abstracts KW - Laboratories KW - Correlations KW - Architecture KW - Expansion KW - Saturation KW - Spectrometry KW - Model Studies KW - Flow Characteristics KW - Carbon KW - Calibrations KW - Nonaqueous Phase Liquids KW - Absorption KW - Laboratory experiments KW - Light transmission KW - SW 0810:General KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - M2 551.508:Instruments (551.508) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20708194?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Water+Resources&rft.atitle=A+modified+light+transmission+visualization+method+for+DNAPL+saturation+measurements+in+2-D+models&rft.au=Bob%2C+M+M%3BBrooks%2C+M+C%3BMravik%2C+S+C%3BWood%2C+AL&rft.aulast=Bob&rft.aufirst=M&rft.date=2008-05-01&rft.volume=31&rft.issue=5&rft.spage=727&rft.isbn=&rft.btitle=&rft.title=Advances+in+Water+Resources&rft.issn=03091708&rft_id=info:doi/10.1016%2Fj.advwatres.2008.01.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Nonaqueous Phase Liquids; Saturation; Model Studies; Calibrations; Absorption; Carbon; Laboratories; Flow Characteristics; Expansion; Correlations; Light transmission; Spectrometry; Architecture; Laboratory experiments DO - http://dx.doi.org/10.1016/j.advwatres.2008.01.016 ER - TY - JOUR T1 - Inferential model estimates of ammonia dry deposition in the vicinity of a swine production facility AN - 20693751; 8185719 AB - This project investigates NH sub(3) dry deposition around a commercial swine production facility in eastern North Carolina. Passive diffusion-tube samplers were used to measure weekly integrated NH sub(3) concentrations at 22 locations along horizontal gradients from the barn/lagoon emissions complex (source) out to a distance of 700m. A two-layer canopy compensation point model was used to predict bi-directional NH sub(3) exchange within a 500m circular buffer surrounding the source. The model takes into account differences in soil and vegetation emission potential, as well as canopy physical characteristics, among three primary surfaces surrounding the site: forest, crops spray fertilized with swine waste, and other fertilized crops. Between June 2003 and July 2005, mean observed NH sub(3) concentrations ranged from 169.0 mu g NH sub(3)m super(-) super(3) at a distance of 10m from the source to 7.1 and 13.0 mu g NH sub(3)m super(-) super(3) at 612 and 698m in the predominant upwind and downwind directions, respectively. Median predicted dry deposition rates ranged from 145kg NH sub(3)-Nha super(-) super(1)yr super(-) super(1) at 10m from the source to 16kg NH sub(3)-Nha super(-) super(1)yr super(-) super(1) at 500m, which is reversible reaction .5x wet deposition of NH sub(4) super(+)-N. Assuming a steady-state emission factor of 7.0kg NH sub(3)animal super(-) super(1)yr super(-) super(1) and a median population of 4900 animals, NH sub(3) dry deposition over the nearest 500m from the barn/lagoon complex accounted for 10.4% (3567kg NH sub(3)) of annual emissions (34,300kgNH sub(3)). A model sensitivity analysis shows that predicted deposition rates are more sensitive to assumptions regarding cuticular uptake relative to soil and vegetation emission potentials. JF - Atmospheric Environment AU - Walker, J AU - Spence, P AU - Kimbrough, S AU - Robarge, W AD - National Risk Management Research Laboratory, Air Pollution Prevention and Control Division, 109 TW Alexander Dr., Mail Drop E305-02, Research Triangle Park, NC 27711, USA, walker.johnt@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 3407 EP - 3418 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 14 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - USA, North Carolina KW - Atmospheric pollution models KW - Forests KW - Animal husbandry KW - Lagoons KW - Crops KW - Soil KW - Fertilizers KW - Model sensitivity KW - sensitivity analysis KW - Emissions KW - Wind KW - Ammonia KW - Sprays KW - Vegetation KW - Ammonia content of atmosphere KW - Wet deposition KW - Forest canopy KW - Dry deposition KW - canopies KW - P 0000:AIR POLLUTION KW - M2 551.5:General (551.5) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20693751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Inferential+model+estimates+of+ammonia+dry+deposition+in+the+vicinity+of+a+swine+production+facility&rft.au=Walker%2C+J%3BSpence%2C+P%3BKimbrough%2C+S%3BRobarge%2C+W&rft.aulast=Walker&rft.aufirst=J&rft.date=2008-05-01&rft.volume=42&rft.issue=14&rft.spage=3407&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.06.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Model sensitivity; Forest canopy; Atmospheric pollution models; Ammonia content of atmosphere; Wet deposition; Dry deposition; Animal husbandry; Ammonia; Sprays; Vegetation; Forests; Lagoons; Crops; Soil; Fertilizers; sensitivity analysis; Emissions; Wind; canopies; USA, North Carolina DO - http://dx.doi.org/10.1016/j.atmosenv.2007.06.004 ER - TY - JOUR T1 - Perfluorooctanoic Acid-Induced Immunomodulation in Adult C57BL/6J or C57BL/6N Female Mice AN - 20691821; 8204344 AB - Background: Perfluorooctanoic acid (PFOA), an environmentally persistent compound of regulatory concern, has been reported to reduce antibody responses in mice at a single dose. Objective: The aim of this study was to evaluate PFOA effects on humoral and cellular immunity using standard assays for assessing immune function, and to derive dose-response data. Methods: C57BL/6J mice received 0 or 30 mg PFOA/kg/day for 10 days; half of the exposed groups were switched to vehicle and half continued on PFOA for five days. C57BL/6N mice received 0-30 mg/kg/day of PFOA in drinking water for 15 days. Mice were immunized with sheep red blood cells or sensitized to bovine serum albumin in Freund's complete adjuvant on day 10 of exposure; immune responses were determined 1 day post-exposure. Results: We found that 30 mg PFOA/kg/day given for 10 or 15 days reduced IgM synthesis; serum collected 1 day postexposure contained 8.4 x 10 super(4) or 2.7 x 10 super(5) ng PFOA/mL, respectively. IgM synthesis was suppressed at exposures greater than or equal to 3.75 mg PFOA/kg/day in a dose-dependent manner, and IgG titers were elevated at 3.75 and 7.5 mg PFOA/kg/day. Serum PFOA at 3.75 mg/kg/day was 7.4 x 10 super(4) ng/mL 1 day postexposure, or 150-fold greater than the levels reported in individuals living near a PFOA production site. Using a second-degree polynomial model, we calculated a benchmark dose of 3 mg/kg/day, with a lower bound (95% confidence limit) of 1.75 mg/kg/day. Cell-mediated function was not affected. Conclusions: IgM antibodies were suppressed after PFOA exposure. The margin of exposure for reduced IgM antibody synthesis was approximately 150 for highly exposed human populations. JF - Environmental Health Perspectives AU - DeWitt, J C AU - Copeland, C B AU - Strynar, MJ AU - Luebke, R W AD - U.S. Environmental Protection Agency, MD B143-01, 109 TW Alexander Dr., Research Triangle Park, NC 27711 USA, luebke.robert@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 644 EP - 650 VL - 116 IS - 5 SN - 0091-6765, 0091-6765 KW - Toxicology Abstracts KW - Sheep red blood cells KW - Immunity (cell-mediated) KW - Bovine serum albumin KW - Immunoglobulin G KW - perfluorooctanoic acid KW - Adjuvants KW - Immune response KW - Drinking water KW - Immunomodulation KW - Immunoglobulin M KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20691821?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Perfluorooctanoic+Acid-Induced+Immunomodulation+in+Adult+C57BL%2F6J+or+C57BL%2F6N+Female+Mice&rft.au=DeWitt%2C+J+C%3BCopeland%2C+C+B%3BStrynar%2C+MJ%3BLuebke%2C+R+W&rft.aulast=DeWitt&rft.aufirst=J&rft.date=2008-05-01&rft.volume=116&rft.issue=5&rft.spage=644&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.10896 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Sheep red blood cells; Bovine serum albumin; Immunity (cell-mediated); Immunoglobulin G; perfluorooctanoic acid; Immune response; Adjuvants; Drinking water; Immunomodulation; Immunoglobulin M DO - http://dx.doi.org/10.1289/ehp.10896 ER - TY - JOUR T1 - Particulate matter, oxidative stress and neurotoxicity AN - 20206857; 8298825 AB - Particulate matter (PM), a component of air pollution has been epidemiologically associated with sudden deaths, cardiovascular and respiratory illnesses. The effects are more pronounced in patients with pre-existing conditions such as asthma, diabetes or obstructive pulmonary disorders. Clinical and experimental studies have historically focused on the cardiopulmonary effects of PM. However, since PM particles carry numerous biocontaminants that are capable of triggering free radical production and cytokine release, the possibility that PM may affect organs systems sensitive to oxidative stress must be considered. Four independent studies that summarize the neurochemical and neuropathological changes found in the brains of PM exposed animals are described here. These were recently presented at two 2007 symposia sponsored by the Society of Toxicology (Charlotte, NC) and the International Neurotoxicology Association (Monterey, CA). JF - Neurotoxicology AU - MohanKumar, SMJ AU - Campbell, A AU - Block, M AU - Veronesi, B AD - National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC, United States, mohankumrs@cvm.msu.edu Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 478 EP - 487 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 29 IS - 3 SN - 0161-813X, 0161-813X KW - Pollution Abstracts; CSA Neurosciences Abstracts; Toxicology Abstracts KW - Mortality KW - Historical account KW - Free radicals KW - Particulate matter KW - Brain KW - Asthma KW - Particulates KW - Respiratory diseases KW - Organs KW - oxidative stress KW - Air pollution KW - Diabetes mellitus KW - diabetes mellitus KW - Oxidative stress KW - Lung KW - USA, California, Monterey KW - Neurotoxicity KW - Toxicology KW - X 24310:Pharmaceuticals KW - P 0000:AIR POLLUTION KW - N3 11024:Neuroimmunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20206857?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Particulate+matter%2C+oxidative+stress+and+neurotoxicity&rft.au=MohanKumar%2C+SMJ%3BCampbell%2C+A%3BBlock%2C+M%3BVeronesi%2C+B&rft.aulast=MohanKumar&rft.aufirst=SMJ&rft.date=2008-05-01&rft.volume=29&rft.issue=3&rft.spage=478&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/10.1016%2Fj.neuro.2007.12.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Diabetes mellitus; Air pollution; Lung; Oxidative stress; Free radicals; Neurotoxicity; Particulate matter; Brain; Asthma; Historical account; Mortality; diabetes mellitus; Respiratory diseases; Particulates; Organs; Toxicology; oxidative stress; USA, California, Monterey DO - http://dx.doi.org/10.1016/j.neuro.2007.12.004 ER - TY - JOUR T1 - Making water reuse more sustainable AN - 20029334; 8352134 AB - BY 2025, at least 3.5 billion people (48 percent of the world's population) are projected to live in water-stressed conditions. Water scarcity is well known in the arid southwest U.S., but is even occurring in the normally water-plentiful southeast (e.g., Florida and Georgia). Today, conservation measures are increasingly viewed as long-range options -- taking shorter showers, using low-flush toilets, reduced watering frequency, xeriscaping, etc. Currently in the U.S., public and domestic uses represent only about 12 percent of total water demand. In places like Florida, about 50 to 70 percent of potable water consumption is used outside, principally for irrigation. JF - Biocycle AU - Bastian, R AU - O'Connor, G AU - Elliott, H AD - USEPA's Office of Wastewater Management in Washington, D.C., USA Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 51 EP - 55 VL - 49 IS - 5 SN - 0276-5055, 0276-5055 KW - Aqualine Abstracts; Sustainability Science Abstracts; Water Resources Abstracts KW - Water Reuse KW - Water Management KW - USA, Florida KW - Potable Water KW - Sustainable development KW - world population KW - water demand KW - Water Demand KW - Water Scarcity KW - Irrigation KW - scarcity KW - USA, Georgia KW - Water reuse KW - Conservation KW - Water wells KW - Irrigation Water KW - Drinking water KW - AQ 00001:Water Resources and Supplies KW - M3 1010:Issues in Sustainable Development KW - SW 1060:Conservation in agricultural use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20029334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biocycle&rft.atitle=Making+water+reuse+more+sustainable&rft.au=Bastian%2C+R%3BO%27Connor%2C+G%3BElliott%2C+H&rft.aulast=Bastian&rft.aufirst=R&rft.date=2008-05-01&rft.volume=49&rft.issue=5&rft.spage=51&rft.isbn=&rft.btitle=&rft.title=Biocycle&rft.issn=02765055&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - world population; Irrigation; Sustainable development; Water wells; Conservation; scarcity; water demand; Drinking water; Water reuse; Water Reuse; Water Management; Water Scarcity; Water Demand; Potable Water; Irrigation Water; USA, Florida; USA, Georgia ER - TY - JOUR T1 - Polymorphic microsatellite loci from northern and Mexican corn rootworms (Insecta: Coleoptera: Chrysomelidae) and cross-amplification with other Diabrotica spp. AN - 19801357; 8226159 AB - The northern corn rootworm (Diabrotica barberi) and Mexican corn rootworm (Diabrotica virgifera zeae) are significant agricultural pests. For the northern corn rootworm, and to a lesser extent, the Mexican corn rootworm, high resolution molecular markers are needed. Here we present 14 polymorphic microsatellite loci isolated from libraries constructed using pooled northern and Mexican corn rootworm genomic DNA. Polymorphism in other Diabrotica, including the banded cucumber beetle, southern corn rootworm and western corn rootworm, is described. JF - Molecular Ecology Resources AU - Waits, Eric R AU - Stolz, Uwe AD - Molecular Ecology Research Branch, National Exposure Research Laboratory, US Environmental Protection Agency, 26 W. Martin Luther King Drive, Cincinnati, OH 45268, USA, waits.eric@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 707 EP - 709 PB - Wiley-Blackwell Publishing Ltd. VL - 8 IS - 3 SN - 1755-098X, 1755-098X KW - Biochemistry Abstracts 2: Nucleic Acids; Genetics Abstracts; Ecology Abstracts; Entomology Abstracts KW - Diabrotica KW - Mexican corn rootworm KW - microsatellites KW - northern corn rootworm KW - Diabrotica KW - Coleoptera KW - Diabrotica virgifera zeae KW - Diabrotica barberi KW - Microsatellites KW - genomics KW - Pests KW - Chrysomelidae KW - Insecta KW - D 04040:Ecosystem and Ecology Studies KW - G 07750:Ecological & Population Genetics KW - Z 05360:Genetics and Evolution KW - N 14845:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19801357?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+Ecology+Resources&rft.atitle=Polymorphic+microsatellite+loci+from+northern+and+Mexican+corn+rootworms+%28Insecta%3A+Coleoptera%3A+Chrysomelidae%29+and+cross-amplification+with+other+Diabrotica+spp.&rft.au=Waits%2C+Eric+R%3BStolz%2C+Uwe&rft.aulast=Waits&rft.aufirst=Eric&rft.date=2008-05-01&rft.volume=8&rft.issue=3&rft.spage=707&rft.isbn=&rft.btitle=&rft.title=Molecular+Ecology+Resources&rft.issn=1755098X&rft_id=info:doi/10.1111%2Fj.1471-8286.2007.02056.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Microsatellites; Pests; genomics; Diabrotica; Coleoptera; Diabrotica virgifera zeae; Diabrotica barberi; Insecta; Chrysomelidae DO - http://dx.doi.org/10.1111/j.1471-8286.2007.02056.x ER - TY - JOUR T1 - Field and laboratory performance characteristics of a new protocol for sampling riverine macroinvertebrate assemblages AN - 19644328; 8235874 AB - Measurement and estimation of performance characteristics (i.e. precision, bias, performance range, interferences and sensitivity) are often neglected in the development and use of biological sampling methods. However, knowledge of this information is critical in enabling potential users to assess data quality and make comparisons among different sampling methods. In this study, the performance characteristics were evaluated for both the field and laboratory components of a new large river macroinvertebrate bioassessment protocol (mLR-BP) for non-wadeable streams. We sampled 19 sites across two depth classes, collecting three replicate samples at each site and sorting three 300-organism subsamples from each sample. The replicate samples provided data for estimates of precision in the laboratory and field, and abiotic variables allowed for measurements of overall sensitivity. Precision and performance range differed between shallow and deep sites, particularly for the field component. As compared with precision measured in other studies of bioassessment methods, the field component of the mLR-BP performed similarly, particularly in shallow sites. Based on the measures of combined field and laboratory sensitivity, this protocol should be able to detect differences of approximately 20-25% in the metrics evaluated in this study, if used for bioassessment in similar types of rivers. With all sites and the field and laboratory components combined, metrics were most responsive to a gradient of urban land cover but also showed some relationship with agricultural land cover. However, metric responsiveness does not necessarily correlate with precision, and metric selection can influence the performance characteristics of the method. Overall, the sampling protocol shows great utility for bioassessment and monitoring of non-wadeable rivers, as well as for measuring the success of restoration efforts. In addition, the design of this study provides a template for estimating performance characteristics in other non-wadeable systems. JF - River Research and Applications AU - Blocksom, Karen A AU - Flotemersch, Joseph E AD - U.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Cincinnati, OH 45268, USA, blocksom.karen@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 373 EP - 387 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk] VL - 24 IS - 4 SN - 1535-1459, 1535-1459 KW - Aqualine Abstracts; Ecology Abstracts; Entomology Abstracts; ASFA 1: Biological Sciences & Living Resources; Water Resources Abstracts KW - Macroinvertebrates KW - Freshwater KW - Streams KW - Utilities KW - Agricultural land KW - Sampling KW - Rivers KW - Biological surveys KW - Laboratories KW - Methodology KW - Performance Evaluation KW - Precision KW - Monitoring KW - Zoobenthos KW - Biological sampling KW - AQ 00001:Water Resources and Supplies KW - Q1 08382:Ecological techniques and apparatus KW - Z 05340:Ecology and Behavior KW - D 04040:Ecosystem and Ecology Studies KW - SW 7060:Research facilities UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19644328?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=River+Research+and+Applications&rft.atitle=Field+and+laboratory+performance+characteristics+of+a+new+protocol+for+sampling+riverine+macroinvertebrate+assemblages&rft.au=Blocksom%2C+Karen+A%3BFlotemersch%2C+Joseph+E&rft.aulast=Blocksom&rft.aufirst=Karen&rft.date=2008-05-01&rft.volume=24&rft.issue=4&rft.spage=373&rft.isbn=&rft.btitle=&rft.title=River+Research+and+Applications&rft.issn=15351459&rft_id=info:doi/10.1002%2Frra.1073 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Biological surveys; Rivers; Sampling; Biological sampling; Zoobenthos; Methodology; Agricultural land; Streams; Performance Evaluation; Laboratories; Precision; Macroinvertebrates; Monitoring; Utilities; Freshwater DO - http://dx.doi.org/10.1002/rra.1073 ER - TY - JOUR T1 - On Indoor Air Pollution Hazards and Prevention Measures AN - 19568989; 8832171 AB - Indoor air quality directly affect people's health, interior decoration and furniture in various sheet so that the use of formaldehyde and other organic matter to indoor pollution getting worse. This paper analyses the source of indoor air pollutants, and the air and human health hazards, outlining the improvement in air quality and indoor air pollution prevention and treatment methods. JF - Environmental Science and Management AU - Zhijin, X AU - Qingbo, C AD - Hailun Environmental Protection Agency, Hailun 152300, China Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 89 EP - 90 PB - China Journal, [mailto:bfhj@vip.163.com], [URL:http://bfhj.chinajournal.net.cn] VL - 33 IS - 5 SN - 1673-1212, 1673-1212 KW - Pollution Abstracts KW - Indoor air pollution KW - Organic matter KW - Environmental health KW - Formaldehyde KW - Air quality KW - Public health KW - Air pollution KW - Hazards KW - prevention KW - Indoor environments KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19568989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+and+Management&rft.atitle=On+Indoor+Air+Pollution+Hazards+and+Prevention+Measures&rft.au=Zhijin%2C+X%3BQingbo%2C+C&rft.aulast=Zhijin&rft.aufirst=X&rft.date=2008-05-01&rft.volume=33&rft.issue=5&rft.spage=89&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+and+Management&rft.issn=16731212&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Hazards; Air pollution; Organic matter; Indoor air pollution; prevention; Formaldehyde; Environmental health; Air quality; Indoor environments; Public health ER - TY - JOUR T1 - Electrocatalytic dechlorination of a PCB congener at a palladized granular-graphite-packed electrode: Reaction equilibrium and mechanism AN - 19558229; 8751975 AB - Our previous study on the electrocatalytic dechlorination of 2- chlorobiphenyl at a Pd-loaded granular graphite-packed electrode demonstrated that the process did not follow the first-order kinetics. The rate constant varied with the applied potential at the beginning, but later became irrelevant to the potential. The electrocatalytic kinetic was investigated in this study, in which several experiments were conducted to dechlorinate 2- chlorobiphenyl using a Pd-loaded granular graphite-packed electrode at different potentials and in methanol-water solutions. Analysis of the experimental results reveals that the electrocatalytic process had reached equilibrium in these experiments. The apparent equilibrium constants, as well as the rate constants for the overall forward and backward reactions, were related to the applied potential. These relationships follow the Tafel equation, but the apparent charge transfer coefficients are very small values. The potential dependence of the overall rate constants suggests a reaction mechanism in which the electrocatalytic reaction is the rate- determining step. The influence of methanol on (together with the potential dependence of) the overall rate constants and the apparent equilibrium constant suggests a Langmuir-Hinshelwood mechanism. JF - Applied Catalysis B: Environmental AU - Fang, Yuanxiang AU - Al-Abed, Souhail R AD - National Risk Management Research Laboratory, USEPA, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, United States, al-abed.souhail@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 327 EP - 334 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 80 IS - 3-4 SN - 0926-3373, 0926-3373 KW - Pollution Abstracts KW - Dechlorination KW - Kinetics KW - Electrodes KW - PCB compounds KW - Catalysis KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19558229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Catalysis+B%3A+Environmental&rft.atitle=Electrocatalytic+dechlorination+of+a+PCB+congener+at+a+palladized+granular-graphite-packed+electrode%3A+Reaction+equilibrium+and+mechanism&rft.au=Fang%2C+Yuanxiang%3BAl-Abed%2C+Souhail+R&rft.aulast=Fang&rft.aufirst=Yuanxiang&rft.date=2008-05-01&rft.volume=80&rft.issue=3-4&rft.spage=327&rft.isbn=&rft.btitle=&rft.title=Applied+Catalysis+B%3A+Environmental&rft.issn=09263373&rft_id=info:doi/10.1016%2Fj.apcatb.2007.11.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Dechlorination; Kinetics; Electrodes; PCB compounds; Catalysis DO - http://dx.doi.org/10.1016/j.apcatb.2007.11.021 ER - TY - JOUR T1 - A calcium-based invasion risk assessment for zebra and quagga mussels (Dreissena spp) AN - 19487079; 8572837 AB - We used calcium concentration data from over 3000 stream and river sites across the contiguous United States to classify ecoreglons relative to their risk for Drelssena species invasion. We defined risk based on calcium concentrations as: very low ( 28 mg L super(-1)). Ecoregions comprising 9.4% and 11.3% of land area were classified as very low risk and low risk, respectively. These areas included New England, most of the southeast, and westem portions of the Pacific Northwest High-risk ecoregions comprised 58.9% of land area. Ecoregions with highly variable calcium concentrations comprised 19.8% of land area; none could be classified as moderate risk. The majority of Dreissena occurrences (excluding the Great Lakes) were located In high-risk ecoregions, and most exceptions occurred in highiy variable ecoregions. In low-risk ecoregions, mussels occurred in large rivers flowing from high-calcium regions. Our map provides guidance for the allocation of management resources. JF - Frontiers in Ecology and the Environment AU - Whlttier, T R AU - Ringold, P L AU - Herllhy, A T AU - Plerson, S M AD - Department of Fisheries and Wildlle, Oregon State University, Corvallis, OR 97333, USA, whittier.thom@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 180 EP - 184 VL - 6 IS - 4 SN - 1540-9295, 1540-9295 KW - Ecology Abstracts; Sustainability Science Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Risk assessment KW - Rivers KW - Geographical distribution KW - Data processing KW - Calcium KW - Freshwater KW - ANW, USA, New England KW - Dreissena KW - Streams KW - INE, USA, Pacific Northwest KW - Ecosystem disturbance KW - Freshwater molluscs KW - Lakes KW - Risk factors KW - North America, Great Lakes KW - invasive species KW - Risk groups KW - Introduced species KW - M3 1010:Issues in Sustainable Development KW - Q1 08262:Geographical distribution KW - Q5 08521:Mechanical and natural changes KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19487079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Frontiers+in+Ecology+and+the+Environment&rft.atitle=A+calcium-based+invasion+risk+assessment+for+zebra+and+quagga+mussels+%28Dreissena+spp%29&rft.au=Whlttier%2C+T+R%3BRingold%2C+P+L%3BHerllhy%2C+A+T%3BPlerson%2C+S+M&rft.aulast=Whlttier&rft.aufirst=T&rft.date=2008-05-01&rft.volume=6&rft.issue=4&rft.spage=180&rft.isbn=&rft.btitle=&rft.title=Frontiers+in+Ecology+and+the+Environment&rft.issn=15409295&rft_id=info:doi/10.1890%2F070073 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Lakes; Geographical distribution; Freshwater molluscs; Calcium; Introduced species; Ecosystem disturbance; Rivers; Risk assessment; Data processing; Risk factors; Risk groups; Streams; invasive species; Dreissena; North America, Great Lakes; ANW, USA, New England; INE, USA, Pacific Northwest; Freshwater DO - http://dx.doi.org/10.1890/070073 ER - TY - JOUR T1 - Economic Evaluation of the US Environmental Protection Agency's SunWise Program: Sun Protection Education for Young Children AN - 19480482; 8202797 AB - OBJECTIVE. The SunWise School Program is a school-based sun safety education program that was developed by the US Environmental Protection Agency and aims to teach children how to protect themselves from overexposure to the sun. The objectives of this study were to assess the health benefits of the SunWise School Program and use economic analysis to determine the program's net benefits and cost-effectiveness. METHODS. Standard cost/benefit and cost-effectiveness analysis methods were used. Intervention costs were measured as program costs estimated to be incurred by the US government, which funds SunWise, using 3 funding scenarios. Health outcomes were measured as skin cancer cases and premature mortalities averted and quality-adjusted life-years saved. These health outcomes were modeled using an effectiveness evaluation of SunWise based on pretest and posttest surveys administered to students who participated in the program and the Environmental Protection Agency's peer-reviewed Atmospheric and Health Effects Framework model. Costs averted were measured as direct medical costs and costs of productivity losses averted as a result of SunWise. Net benefits were measured as the difference between costs averted and program costs. RESULTS. Economic analysis indicated that if the SunWise School Program continues through 2015 at current funding levels, then it should avert >50 premature deaths, nearly 11000 skin cancer cases, and 960 quality-adjusted life-years (undiscounted) among its participants. For every dollar invested in SunWise, between approximately $2 and $4 in medical care costs and productivity losses are saved, depending on the funding scenario. CONCLUSIONS. From a cost/benefit and cost-effectiveness perspective, it is worthwhile to educate children about sun safety; small to modest behavioral impacts may result in significant reductions in skin cancer incidence and mortality. JF - Pediatrics AU - Kyle, Jessica W AU - Hammitt, James K AU - Lim, Henry W AU - Geller, Alan C AU - Hall-Jordan, Luke H AU - Maibach, Edward W AU - De Fabo, Edward C AU - Wagner, Mark C AD - ICF International, Washington, DC. Center for Risk Analysis, Harvard University, Boston, Massachusetts. Department of Dermatology, Henry Ford Hospital, Detroit, Michigan. Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts. US Environmental Protection Agency, Washington, DC. Center of Excellence in Climate Change Communication Research, Department of Communication, George Mason University, Fairfax, Virginia. Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, George Washington University Medical Center, Washington, DC Y1 - 2008/05// PY - 2008 DA - May 2008 SP - e1074 EP - e1084 PB - American Academy of Pediatrics, 141 Northwest Point Blvd. Elk Grove Village IL 60007-1098 USA, [mailto:journals@aap.org], [URL:http://www.aap.org] VL - 121 IS - 5 SN - 0031-4005, 0031-4005 KW - Health & Safety Science Abstracts KW - Cost-benefit analysis KW - schools KW - intervention KW - Economics KW - Sun KW - Mortality KW - Skin KW - Children KW - Cancer KW - EPA KW - Education KW - USA KW - funds KW - economic analysis KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19480482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatrics&rft.atitle=Economic+Evaluation+of+the+US+Environmental+Protection+Agency%27s+SunWise+Program%3A+Sun+Protection+Education+for+Young+Children&rft.au=Kyle%2C+Jessica+W%3BHammitt%2C+James+K%3BLim%2C+Henry+W%3BGeller%2C+Alan+C%3BHall-Jordan%2C+Luke+H%3BMaibach%2C+Edward+W%3BDe+Fabo%2C+Edward+C%3BWagner%2C+Mark+C&rft.aulast=Kyle&rft.aufirst=Jessica&rft.date=2008-05-01&rft.volume=121&rft.issue=5&rft.spage=e1074&rft.isbn=&rft.btitle=&rft.title=Pediatrics&rft.issn=00314005&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA; Cancer; schools; Sun; Cost-benefit analysis; Mortality; Skin; EPA; Children; economic analysis; Education; Economics; intervention; funds ER - TY - JOUR T1 - Comparability of a regional and state survey: effects on fish IBI assessment for West Virginia, U.S.A. AN - 19472900; 8168548 AB - Probability-based survey designs are now being investigated to allow condition to be assessed for a discrete population of watershed management units and to infer probability of impairment to other unsampled watersheds. Results can be used to focus further monitoring and restoration efforts. Fish community data and index of biotic integrity (IBI) development were compared between the 1993 and 1998 Environmental Monitoring and Assessment Program Mid-Atlantic Integrated Assessment (EMAP-MAIA) survey and a West Virginia Regional EMAP (WV REMAP) survey conducted in 2001-2002. Both designs were based on probability surveys, but the EMAP design treated streams as a continuous linear network comprising an infinite population of points, while the REMAP design used a discrete set of watershed outlets as defined by 12-digit Hydrologic Cataloging Units (HUC12) as the sample population. The comparability of the watershed-based WV REMAP survey design results with the linear network-based EMAP-MAIA survey results for West Virginia was affected by the different size range of watershed areas included in each target population. Once similar watershed area ranges were considered by narrowing the size range included in the West Virginia EMAP-MAIA data set, virtually identical cumulative distribution functions for fish IBI scores were obtained. The reduced variability in reference conditions obtained by applying a restricted range of watershed areas allowed us to detect and correct for ecoregional differences in fish IBI metrics and scores, after excluding the biogeographically distinct Potomac River drainage basin located in the Central Appalachian Ridge and Valley Ecoregion. JF - Hydrobiologia AU - Detenbeck, Naomi E AU - Cincotta, Daniel A AD - US Environmental Protection Agency (US EPA), 27 Tarzwell Drive, Narragansett, RI, 02882, USA, detenbeck.naomi@epa.gov Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 279 EP - 300 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de] VL - 603 IS - 1 SN - 0018-8158, 0018-8158 KW - Pollution Abstracts; Sustainability Science Abstracts; Ecology Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Basins KW - Freshwater KW - Watersheds KW - Freshwater fish KW - Streams KW - Restoration KW - USA, Maryland, Potomac R. KW - River basin management KW - Rivers KW - Biological surveys KW - Environmental monitoring KW - valleys KW - Biogeography KW - Drainage KW - River basins KW - USA, West Virginia KW - ridges KW - Environmental conditions KW - D 04070:Pollution KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - Q1 08602:Surveying and prospecting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19472900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Hydrobiologia&rft.atitle=Comparability+of+a+regional+and+state+survey%3A+effects+on+fish+IBI+assessment+for+West+Virginia%2C+U.S.A.&rft.au=Detenbeck%2C+Naomi+E%3BCincotta%2C+Daniel+A&rft.aulast=Detenbeck&rft.aufirst=Naomi&rft.date=2008-05-01&rft.volume=603&rft.issue=1&rft.spage=279&rft.isbn=&rft.btitle=&rft.title=Hydrobiologia&rft.issn=00188158&rft_id=info:doi/10.1007%2Fs10750-008-9278-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Biological surveys; Biogeography; River basins; Freshwater fish; Environmental conditions; Watersheds; River basin management; Restoration; Rivers; Drainage; Basins; Streams; ridges; valleys; USA, Maryland, Potomac R.; USA, West Virginia; Freshwater DO - http://dx.doi.org/10.1007/s10750-008-9278-3 ER - TY - JOUR T1 - Distribution of total and methylmercury in different ecosystem compartments in the Everglades; implications for mercury bioaccumulation AN - 1316372976; 2013-025808 AB - We analyzed Hg species distribution patterns among ecosystem compartments in the Everglades at the landscape level in order to explore the implications of Hg distribution for Hg bioaccumulation and to investigate major biogeochemical processes that are pertinent to the observed Hg distribution patterns. At an Everglade-wide scale, THg concentrations were significantly increased in the following order: periphyton < flocculent material (floc) < soil, while relatively high MeHg concentrations were observed in floc and periphyton. Differences in the methylation potential, THg concentration, and MeHg retention capacity could explain the relatively high MeHg concentrations in floc and periphyton. The MeHg/THg ratio was higher for water than for soil, floc, or periphyton probably due to high dissolved organic carbon (DOC) concentrations present in the Everglades. Mosquitofish THg positively correlated with periphyton MeHg and DOC-normalized water MeHg. The relative THg and MeHg distribution patterns among ecosystem compartments favor Hg bioaccumulation in the Everglades. Abstract Copyright (2008) Elsevier, B.V. JF - Environmental Pollution (1987) AU - Liu, Guangliang AU - Cai, Yong AU - Philippi, Thomas AU - Kalla, Peter AU - Scheidt, Daniel AU - Richards, Jennifer AU - Scinto, Leonard AU - Appleby, Charlie Y1 - 2008/05// PY - 2008 DA - May 2008 SP - 257 EP - 265 PB - Elsevier, Barking VL - 153 IS - 2 SN - 0269-7491, 0269-7491 KW - United States KW - ecosystems KW - Florida KW - bioaccumulation KW - conservation KW - carbon KW - organic carbon KW - mercury KW - soils KW - concentration KW - toxic materials KW - patterns KW - Everglades KW - surface water KW - solutes KW - pollution KW - correlation KW - organo-metallics KW - distribution KW - methylmercury KW - metals KW - seasonal variations KW - landscapes KW - water resources KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1316372976?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Pollution+%281987%29&rft.atitle=Distribution+of+total+and+methylmercury+in+different+ecosystem+compartments+in+the+Everglades%3B+implications+for+mercury+bioaccumulation&rft.au=Liu%2C+Guangliang%3BCai%2C+Yong%3BPhilippi%2C+Thomas%3BKalla%2C+Peter%3BScheidt%2C+Daniel%3BRichards%2C+Jennifer%3BScinto%2C+Leonard%3BAppleby%2C+Charlie&rft.aulast=Liu&rft.aufirst=Guangliang&rft.date=2008-05-01&rft.volume=153&rft.issue=2&rft.spage=257&rft.isbn=&rft.btitle=&rft.title=Environmental+Pollution+%281987%29&rft.issn=02697491&rft_id=info:doi/10.1016%2Fj.envpol.2007.08.030 L2 - http://www.sciencedirect.com/science/journal/02697491 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2013-01-01 N1 - Document feature - illus. incl. 5 tables, sketch map N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2013-03-14 N1 - CODEN - ENVPAF N1 - SubjectsTermNotLitGenreText - bioaccumulation; carbon; concentration; conservation; correlation; distribution; ecosystems; Everglades; Florida; landscapes; mercury; metals; methylmercury; organic carbon; organo-metallics; patterns; pollution; seasonal variations; soils; solutes; surface water; toxic materials; United States; water resources DO - http://dx.doi.org/10.1016/j.envpol.2007.08.030 ER - TY - CPAPER T1 - Fumigant Emission Physical Factors and Measures for Mitigating Exposure Incidences T2 - 18th Conference on Atmospheric Biogeosciences AN - 40849379; 4817348 JF - 18th Conference on Atmospheric Biogeosciences AU - Rothman, Gabriel S Y1 - 2008/04/28/ PY - 2008 DA - 2008 Apr 28 KW - Mitigation KW - Fumigants KW - Emissions KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40849379?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=18th+Conference+on+Atmospheric+Biogeosciences&rft.atitle=Fumigant+Emission+Physical+Factors+and+Measures+for+Mitigating+Exposure+Incidences&rft.au=Rothman%2C+Gabriel+S&rft.aulast=Rothman&rft.aufirst=Gabriel&rft.date=2008-04-28&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=18th+Conference+on+Atmospheric+Biogeosciences&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/28Hurricanes/techprogram/programexpanded_494 .htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Great Lakes National Program Office - Program Introduction and Recent Initiatives. T2 - 42nd Annual Meeting of the North-Central Section, Geological Society of America (GSA 2008) AN - 40913358; 4842469 JF - 42nd Annual Meeting of the North-Central Section, Geological Society of America (GSA 2008) AU - Bolen, Bill Y1 - 2008/04/23/ PY - 2008 DA - 2008 Apr 23 KW - North America, Great Lakes KW - Lakes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40913358?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=42nd+Annual+Meeting+of+the+North-Central+Section%2C+Geological+Society+of+America+%28GSA+2008%29&rft.atitle=Great+Lakes+National+Program+Office+-+Program+Introduction+and+Recent+Initiatives.&rft.au=Bolen%2C+Bill&rft.aulast=Bolen&rft.aufirst=Bill&rft.date=2008-04-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=42nd+Annual+Meeting+of+the+North-Central+Section%2C+Geological+Society+of+America+%28GSA+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2008NC/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of NLCD Products at EPA to Map Ecological Goods and Services T2 - 2008 Annual Meeting of the Association of American Geographers (AAG 2008) AN - 40876527; 4828453 JF - 2008 Annual Meeting of the Association of American Geographers (AAG 2008) AU - Wickham, James Y1 - 2008/04/15/ PY - 2008 DA - 2008 Apr 15 KW - EPA KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40876527?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2008%29&rft.atitle=Use+of+NLCD+Products+at+EPA+to+Map+Ecological+Goods+and+Services&rft.au=Wickham%2C+James&rft.aulast=Wickham&rft.aufirst=James&rft.date=2008-04-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=53 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Energy and the Spatial Distribution of Corn Ethanol Supply T2 - 2008 Annual Meeting of the Association of American Geographers (AAG 2008) AN - 40864123; 4824830 JF - 2008 Annual Meeting of the Association of American Geographers (AAG 2008) AU - Gamas, Julia Andrea Y1 - 2008/04/15/ PY - 2008 DA - 2008 Apr 15 KW - Ethanol KW - Corn KW - Spatial distribution KW - Energy KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40864123?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2008%29&rft.atitle=Energy+and+the+Spatial+Distribution+of+Corn+Ethanol+Supply&rft.au=Gamas%2C+Julia+Andrea&rft.aulast=Gamas&rft.aufirst=Julia&rft.date=2008-04-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/index.cfm?mtgID=53 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In Vitro Toxicity Screening by Transcription Factor Activity Profiling T2 - 14th Annual Conference and Exhibition of the Society for Biomolecular Sciences AN - 40955510; 4869408 JF - 14th Annual Conference and Exhibition of the Society for Biomolecular Sciences AU - Houck, Keith AU - Dix, David AU - Romanov, Sergei AU - Medvedev, Alexander AU - Gambarian, Maria AU - Poltoratskaya, Natalia AU - Moeser, Matt AU - Medvedeva, Liubov AU - Gambarian, Mikhail AU - Diatchenko, Luda AU - Makarov, Sergei Y1 - 2008/04/06/ PY - 2008 DA - 2008 Apr 06 KW - Toxicity KW - Transcription factors KW - Screening KW - Profiling UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40955510?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Annual+Conference+and+Exhibition+of+the+Society+for+Biomolecular+Sciences&rft.atitle=In+Vitro+Toxicity+Screening+by+Transcription+Factor+Activity+Profiling&rft.au=Houck%2C+Keith%3BDix%2C+David%3BRomanov%2C+Sergei%3BMedvedev%2C+Alexander%3BGambarian%2C+Maria%3BPoltoratskaya%2C+Natalia%3BMoeser%2C+Matt%3BMedvedeva%2C+Liubov%3BGambarian%2C+Mikhail%3BDiatchenko%2C+Luda%3BMakarov%2C+Sergei&rft.aulast=Houck&rft.aufirst=Keith&rft.date=2008-04-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Annual+Conference+and+Exhibition+of+the+Society+for+Biomolecular+Sciences&rft.issn=&rft_id=info:doi/ L2 - http://www.sbsonline.org/sbscon/2008/pdf/Poster_guide.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-25 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Recovering from Contamination: Accessing Treatment and Decontamination Information with EPAs Water Contaminant Information Tool (WCIT) T2 - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AN - 40820246; 4805138 JF - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AU - Apodaca, Lori E AU - Beumel, Gregory A Y1 - 2008/04/02/ PY - 2008 DA - 2008 Apr 02 KW - Decontamination KW - EPA KW - Contaminants KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40820246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.atitle=Recovering+from+Contamination%3A+Accessing+Treatment+and+Decontamination+Information+with+EPAs+Water+Contaminant+Information+Tool+%28WCIT%29&rft.au=Apodaca%2C+Lori+E%3BBeumel%2C+Gregory+A&rft.aulast=Apodaca&rft.aufirst=Lori&rft.date=2008-04-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.newwa.org/PDF/April%202008%20ProgramFINAL.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Energy Management, How to Save Money $$ T2 - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AN - 40819280; 4805106 JF - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AU - Turgeon, Jason Y1 - 2008/04/02/ PY - 2008 DA - 2008 Apr 02 KW - Energy KW - Economics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40819280?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.atitle=Energy+Management%2C+How+to+Save+Money+%24%24&rft.au=Turgeon%2C+Jason&rft.aulast=Turgeon&rft.aufirst=Jason&rft.date=2008-04-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.newwa.org/PDF/April%202008%20ProgramFINAL.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Developing a Consequence Management Plan for a Contamination Warning System T2 - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AN - 40816389; 4805140 JF - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AU - Fencil, Jeffrey Y1 - 2008/04/02/ PY - 2008 DA - 2008 Apr 02 KW - Warning systems KW - Management plans KW - Contamination KW - Environment management KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40816389?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.atitle=Developing+a+Consequence+Management+Plan+for+a+Contamination+Warning+System&rft.au=Fencil%2C+Jeffrey&rft.aulast=Fencil&rft.aufirst=Jeffrey&rft.date=2008-04-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.newwa.org/PDF/April%202008%20ProgramFINAL.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - WARN Update: What You Need to Do T2 - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AN - 40816162; 4805141 JF - Spring Joint Regionial Conference and Exhibition of the New England Water Works Association (NEWWA 2008) AU - Reilly, J Kevin Y1 - 2008/04/02/ PY - 2008 DA - 2008 Apr 02 KW - Security KW - Emergencies KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40816162?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.atitle=WARN+Update%3A+What+You+Need+to+Do&rft.au=Reilly%2C+J+Kevin&rft.aulast=Reilly&rft.aufirst=J&rft.date=2008-04-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Spring+Joint+Regionial+Conference+and+Exhibition+of+the+New+England+Water+Works+Association+%28NEWWA+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.newwa.org/PDF/April%202008%20ProgramFINAL.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Metal release from bottom sediments of Ocoee Lake No. 3, a primary catchment area for the Ducktown mining district AN - 849007523; 2011-016669 JF - Journal of Environmental Quality AU - Lee, Giehyeon AU - Faure, Gunter AU - Bigham, Jerry M AU - Williams, David J Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 344 EP - 352 PB - American Society of Agronomy, [and] Crop Science Society of America, [and] Soil Science Society of America, Madison, WI VL - 37 IS - 2 SN - 0047-2425, 0047-2425 KW - United States KW - hydrology KW - sorption KW - Ocoee Lake KW - desorption KW - acid mine drainage KW - pollutants KW - Ducktown mining district KW - pollution KW - Ducktown Tennessee KW - Polk County Tennessee KW - limnology KW - Tennessee KW - sediments KW - lacustrine environment KW - drainage basins KW - trace metals KW - pH KW - heavy metals KW - lake sediments KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/849007523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Quality&rft.atitle=Metal+release+from+bottom+sediments+of+Ocoee+Lake+No.+3%2C+a+primary+catchment+area+for+the+Ducktown+mining+district&rft.au=Lee%2C+Giehyeon%3BFaure%2C+Gunter%3BBigham%2C+Jerry+M%3BWilliams%2C+David+J&rft.aulast=Lee&rft.aufirst=Giehyeon&rft.date=2008-04-01&rft.volume=37&rft.issue=2&rft.spage=344&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Quality&rft.issn=00472425&rft_id=info:doi/10.2134%2Fjeq2007.0223 L2 - http://jeq.scijournals.org/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 41 N1 - PubXState - WI N1 - Document feature - illus. incl. 4 tables N1 - Last updated - 2012-06-07 N1 - CODEN - JEVQAA N1 - SubjectsTermNotLitGenreText - acid mine drainage; desorption; drainage basins; Ducktown mining district; Ducktown Tennessee; heavy metals; hydrology; lacustrine environment; lake sediments; limnology; Ocoee Lake; pH; Polk County Tennessee; pollutants; pollution; sediments; sorption; Tennessee; trace metals; United States DO - http://dx.doi.org/10.2134/jeq2007.0223 ER - TY - JOUR T1 - Tide-induced seawater-groundwater circulation in shallow beach aquifers AN - 756291720; 2010-081531 AB - In this paper, we investigated the tide-induced seawater-groundwater circulation in shallow beach aquifers using the finite element model MARUN. The numerical solutions were generalized using a dimensionless formulation. From a dimensionless tidal period and a dimensionless beach slope of 10%, we obtained results that apply to a wide range of beach permeabilities from 10 (super -4) m/s to 10 (super -3) m/s, beach slopes from 3.16% to 31.6%, tidal amplitude (0.3m-2m) and period (diurnal or semidiurnal). The numerical simulations demonstrated the following: The maximum Darcy velocity always occurs at the intersection of the watertable and the beach surface. The offshore beach groundwater is almost stagnant compared with the onshore groundwater flow, which may explain the previous observations that the major portion of the seaward groundwater seepage usually occurs in the shallow part of the submerged beach. The outflow from the seepage face accounts for 41-97% (average 55%) of the outflow from the intertidal zone. The amount of seawater infiltrating into the intertidal zone in a tidal cycle increases with the beach permeability and decreases when the inland recharge increases, and ranges from 35.5 m (super 3) yr (super -1) m (super -1) to 505.8 m (super 3) yr (super -1) m (super -1) for all the cases considered. Smaller beach slopes, smaller inland freshwater recharges, and/or greater beach permeability lead to larger saltwater plumes in the intertidal zone of the beach. The results are in line with the existing results of field observations and numerical simulations by previous researchers. JF - Journal of Hydrology AU - Li, Hailong AU - Boufadel, Michel C AU - Weaver, James W Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 211 EP - 224 PB - Elsevier, Amsterdam VL - 352 IS - 1-2 SN - 0022-1694, 0022-1694 KW - solute transport KW - sea water KW - numerical models KW - MARUN KW - data processing KW - seepage KW - ground water KW - aquifers KW - tides KW - finite element analysis KW - beaches KW - recharge KW - intertidal environment KW - transport KW - digital simulation KW - coastal environment KW - shallow aquifers KW - hydraulic conductivity KW - permeability KW - coastal aquifers KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/756291720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hydrology&rft.atitle=Tide-induced+seawater-groundwater+circulation+in+shallow+beach+aquifers&rft.au=Li%2C+Hailong%3BBoufadel%2C+Michel+C%3BWeaver%2C+James+W&rft.aulast=Li&rft.aufirst=Hailong&rft.date=2008-04-01&rft.volume=352&rft.issue=1-2&rft.spage=211&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hydrology&rft.issn=00221694&rft_id=info:doi/10.1016%2Fj.jhydrol.2008.01.013 L2 - http://www.sciencedirect.com/science/journal/00221694 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2010-01-01 N1 - Document feature - illus. incl. 2 tables N1 - SuppNotes - Based on Publisher-supplied data; includes appendix N1 - Last updated - 2012-06-07 N1 - CODEN - JHYDA7 N1 - SubjectsTermNotLitGenreText - aquifers; beaches; coastal aquifers; coastal environment; data processing; digital simulation; finite element analysis; ground water; hydraulic conductivity; intertidal environment; MARUN; numerical models; permeability; recharge; sea water; seepage; shallow aquifers; solute transport; tides; transport DO - http://dx.doi.org/10.1016/j.jhydrol.2008.01.013 ER - TY - JOUR T1 - Physical and chemical characterization of residential oil boiler emissions. AN - 70768564; 18504987 AB - The toxicity of emissions from the combustion of home heating oil coupled with the regional proximity and seasonal use of residential oil boilers (ROB) is an important public health concern. Yet scant physical and chemical information about the emissions from this source is available for climate and air quality modeling and for improving our understanding of aerosol-related human health effects. The gas- and particle-phase emissions from an active ROB firing distillate fuel oil (commonly known as diesel fuel) were evaluated to address this deficiency. Ion chromatography of impactor samples showed that the ultrafine ROB aerosol emissions were approximately 45% (w/w) sulfate. Gas chromatography-mass spectrometry detected various n-alkanes at trace levels, sometimes in accumulation mode particles, and out of phase with the size distributions of aerosol mass and sulfate. The carbonaceous matter in the ROB aerosol was primarily light-adsorbing elemental carbon. Gas chromatography-atomic emission spectroscopy measured a previously unrecognized organosulfur compound group in the ROB aerosol emissions. High-resolution transmission electron microscopy of ROB soot indicated the presence of a highly ordered primary particle nanostructure embedded in larger aggregates. Organic gas emissions were measured using EPA Methods TO-15 and TO-11A. The ROB emitted volatile oxygenates (8 mg/(kg of oil burned)) and olefins (5 mg/(kg of oil burned)) mostly unrelated to the base fuel composition. In the final analysis, the ROB tested was a source of numerous hazardous air pollutants as defined in the Clean Air Act Amendments. Approximations conducted using emissions data from the ROB tests show relatively low contributions to a regional-level anthropogenic emissions inventory for volitile organic compounds, PM2.5, and SO2 mass. JF - Environmental science & technology AU - Hays, Michael D AU - Beck, Lee AU - Barfield, Pamela AU - Lavrich, Richard J AU - Dong, Yuanji AU - Vander Wal, Randy L AD - National Risk Management Research Laboratory, United States Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. hays.michael@epa.gov Y1 - 2008/04/01/ PY - 2008 DA - 2008 Apr 01 SP - 2496 EP - 2502 VL - 42 IS - 7 SN - 0013-936X, 0013-936X KW - Oils KW - 0 KW - Sulfur KW - 70FD1KFU70 KW - Index Medicus KW - Particle Size KW - Gas Chromatography-Mass Spectrometry KW - Sulfur -- chemistry KW - Microscopy, Electron, Scanning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70768564?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Physical+and+chemical+characterization+of+residential+oil+boiler+emissions.&rft.au=Hays%2C+Michael+D%3BBeck%2C+Lee%3BBarfield%2C+Pamela%3BLavrich%2C+Richard+J%3BDong%2C+Yuanji%3BVander+Wal%2C+Randy+L&rft.aulast=Hays&rft.aufirst=Michael&rft.date=2008-04-01&rft.volume=42&rft.issue=7&rft.spage=2496&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-21 N1 - Date created - 2008-05-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat. AN - 70383984; 18096570 AB - Many chemicals released into the environment are capable of disrupting normal sex steroid balance, including the oral contraceptive ethinyl estradiol (EE) and the plastic monomer bisphenol A (BPA). EE and BPA are reported to impair reproductive organ development in laboratory animals; however, effects of lower doses of these chemicals have been debated. The goal of the current study was to determine whether relatively low oral doses of EE or BPA would alter male reproductive morphology and associated hormone levels of Long Evans hooded rat. Dams were gavaged with corn oil vehicle, EE (0.05-50 mug/kg/day) or BPA (2, 20, and 200 mug/kg/day) during pregnancy through lactation from gestational day 7 to postnatal day (PND) 18. Anogenital distance was measured at PND2 and nipple retention was measured at PND14 in male pups. Male offspring were euthanized beginning at PND150, and sera and organs were collected for analyses. Adult body weight was significantly decreased in males exposed to 50 mug EE/kg/day. Developmental EE exposure reduced androgen-dependent tissue weights in a dose-dependent fashion; for example, seminal vesicle and paired testes weights were reduced with >/= 5 mug EE/kg/day. Epididymal sperm counts were also significantly decreased with 50 mug EE/kg/day. In contrast, treatment with 2, 20, or 200 mug BPA/kg/day or EE at 0.05-1.5 mug/kg/day did not significantly affect any male endpoint in the current study. These results demonstrate that developmental exposure to oral micromolar doses of EE can permanently disrupt the reproductive tract of the male rat. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Howdeshell, Kembra L AU - Furr, Johnathan AU - Lambright, Christy R AU - Wilson, Vickie S AU - Ryan, Bryce C AU - Gray, L Earl AD - US Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Reproductive Toxicology Division, Research Triangle Park, North Carolina 27711, USA. howdeshell.kembra@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 371 EP - 382 VL - 102 IS - 2 KW - Benzhydryl Compounds KW - 0 KW - Environmental Pollutants KW - Estrogens KW - Phenols KW - Ethinyl Estradiol KW - 423D2T571U KW - bisphenol A KW - MLT3645I99 KW - Index Medicus KW - Anal Canal -- abnormalities KW - Anal Canal -- drug effects KW - Animals KW - Rats, Long-Evans KW - Dose-Response Relationship, Drug KW - Epididymis -- pathology KW - Testis -- pathology KW - Spermatozoa -- pathology KW - Seminal Vesicles -- drug effects KW - Seminal Vesicles -- pathology KW - Maternal Exposure KW - Pregnancy KW - Anal Canal -- pathology KW - Rats KW - Animals, Newborn KW - Testis -- drug effects KW - Sperm Count KW - Spermatozoa -- drug effects KW - Body Weight -- drug effects KW - Epididymis -- drug effects KW - Female KW - Male KW - Organ Size -- drug effects KW - Prenatal Exposure Delayed Effects -- pathology KW - Lactation -- drug effects KW - Environmental Pollutants -- toxicity KW - Genitalia, Male -- drug effects KW - Prenatal Exposure Delayed Effects -- chemically induced KW - Genitalia, Male -- pathology KW - Genitalia, Male -- abnormalities KW - Phenols -- toxicity KW - Ethinyl Estradiol -- toxicity KW - Estrogens -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70383984?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Gestational+and+lactational+exposure+to+ethinyl+estradiol%2C+but+not+bisphenol+A%2C+decreases+androgen-dependent+reproductive+organ+weights+and+epididymal+sperm+abundance+in+the+male+long+evans+hooded+rat.&rft.au=Howdeshell%2C+Kembra+L%3BFurr%2C+Johnathan%3BLambright%2C+Christy+R%3BWilson%2C+Vickie+S%3BRyan%2C+Bryce+C%3BGray%2C+L+Earl&rft.aulast=Howdeshell&rft.aufirst=Kembra&rft.date=2008-04-01&rft.volume=102&rft.issue=2&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=1096-0929&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-10 N1 - Date created - 2008-03-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Saga of a sperm fertility biomarker. AN - 70361116; 18215478 AB - A decade ago a novel sperm protein associated with the fertility of sperm was discovered by quantifying individual proteins in the sperm membrane proteome of cauda epididymal sperm from rats exposed to epididymal toxicants that compromised the fertility of these sperm. Upon identification, this protein (SP22) was found to a ubiquitous, highly conserved protein never before observed in the male reproductive tract. The expression of SP22 in sperm appears driven by a testis specific mRNA transcript, and the molecule is translocated from the cytoplasmic droplet of rete testis sperm to the equatorial segment of epididymal and ejaculated sperm. The appearance of SP22 mRNA and protein coincide with the formation of pachytene spermatocytes and round spermatids, respectively, and given this testis ontogeny of SP22, we validated its use as a biomarker of fertility by extending our studies to toxicants that target spermiogenesis. Studies of both epididymal and testicular toxicants now have demonstrated that compromised SP22 gene expression is sensitive and correlated with fertility. Importantly, this applies to ejaculated sperm as well as epididymal sperm. With the goal of developing a user-friendly diagnostic assay for SP22 on epididymal and ejaculated sperm, we are attempting to identify exposed, functional domains of the protein. For this, we have generated antibodies to both full length and truncated SP22 recombinants, as well as antibodies to synthetic SP22 peptides. Each antibody has been characterized for its ability to inhibit fertilization both in utero and in vitro. Linear epitope mapping has been done for each antibody, and synthetic peptides corresponding to each epitope have been used in competition experiments designed to elucidate exposure on the sperm surface and function. Most of the linear epitopes identified appear to be exposed although there are relative differences in the degree of their exposure. Interestingly, one of the exposed epitopes does not appear to be functional, at least by itself. Many more domains of the molecule need to be studied, but based on our findings with the epitopes already identified, it seems a combinatorial targeting strategy may be beneficial. If one assumes that the protein's role in fertility resides in a single exposed epitope, or some combination of exposed epitopes, such targeting may also ultimately lead to successful modulation of the fertilizing potential of sperm. JF - Animal reproduction science AU - Klinefelter, Gary R AD - United States Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Reproductive Toxicology Division, MD#72, Research Triangle Park, NC 27711, USA. klinefelter.gary@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 90 EP - 103 VL - 105 IS - 1-2 SN - 0378-4320, 0378-4320 KW - Biomarkers KW - 0 KW - Epitopes KW - Microtubule-Associated Proteins KW - RNA, Messenger KW - Index Medicus KW - Animals KW - Testis -- metabolism KW - Reproducibility of Results KW - Humans KW - Rabbits KW - Amino Acid Sequence KW - Mice KW - RNA, Messenger -- genetics KW - Rats KW - RNA, Messenger -- metabolism KW - Molecular Sequence Data KW - Gene Expression Regulation KW - Epitopes -- immunology KW - Female KW - Male KW - Spermatozoa -- physiology KW - Microtubule-Associated Proteins -- genetics KW - Microtubule-Associated Proteins -- physiology KW - Microtubule-Associated Proteins -- immunology KW - Fertility -- physiology KW - Spermatozoa -- ultrastructure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70361116?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Animal+reproduction+science&rft.atitle=Saga+of+a+sperm+fertility+biomarker.&rft.au=Klinefelter%2C+Gary+R&rft.aulast=Klinefelter&rft.aufirst=Gary&rft.date=2008-04-01&rft.volume=105&rft.issue=1-2&rft.spage=90&rft.isbn=&rft.btitle=&rft.title=Animal+reproduction+science&rft.issn=03784320&rft_id=info:doi/10.1016%2Fj.anireprosci.2007.11.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-23 N1 - Date created - 2008-03-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.anireprosci.2007.11.021 ER - TY - JOUR T1 - Thyroid disrupting chemicals: mechanisms and mixtures. AN - 70351857; 18217984 AB - Environmental contaminants are known to act as thyroid disrupting chemicals (TDCs). Broadly defined, TDCs are xenobiotics that alter the structure or function of the thyroid gland, alter regulatory enzymes associated with thyroid hormone (TH) homeostasis or change circulating or tissue concentrations of THs. For THs, homeostasis is defined as the normal range of THs and TSH in circulation and tissues. TDCs include a wide range chemical structures that act through a variety of mechanisms. Concern about TDCs has increased because of the critical role that thyroid hormones play in brain development. A major uncertainty regarding the endocrine disrupting potential of environmental xenobiotics is the potential for additive, antagonistic or synergistic effects following exposure to mixtures. In addition, there are a number of uncertainties in both interpretation and extrapolation of results from studies of TDC mixtures. Extrapolation of data from laboratory animals to humans is tempered by uncertainty in how the mechanism(s)-of-action of the TDCs may differ between species. The variety of mechanisms by which TDCs alter thyroid homeostasis also yields a difficulty in determining at what level of biological organization to cumulate effects. Should it be at the molecular level, which could be chemical class specific or at the level of a downstream consequence (e.g. circulating hormone levels, brain biochemistry and behaviour) which would be mechanism-independent? To date, the limited data from TDC mixture studies suggest that dose addition is reasonably accurate in predicting the effects on serum T4 concentrations. Assessing the health risks of thyroid disruption by environmental xenobiotics will need to include an improved understanding of how divergent mechanisms alter THs and consequent adverse impacts on nervous system development. JF - International journal of andrology AU - Crofton, Kevin M AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. crofton.kevin@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 209 EP - 223 VL - 31 IS - 2 KW - Endocrine Disruptors KW - 0 KW - Thyroid Hormones KW - Index Medicus KW - Animals KW - Humans KW - Thyroid Hormones -- metabolism KW - Endocrine Disruptors -- toxicity KW - Thyroid Gland -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70351857?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+andrology&rft.atitle=Thyroid+disrupting+chemicals%3A+mechanisms+and+mixtures.&rft.au=Crofton%2C+Kevin+M&rft.aulast=Crofton&rft.aufirst=Kevin&rft.date=2008-04-01&rft.volume=31&rft.issue=2&rft.spage=209&rft.isbn=&rft.btitle=&rft.title=International+journal+of+andrology&rft.issn=1365-2605&rft_id=info:doi/10.1111%2Fj.1365-2605.2007.00857.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-04 N1 - Date created - 2008-03-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1365-2605.2007.00857.x ER - TY - JOUR T1 - Early life and adult exposure to isoflavones and breast cancer risk. AN - 69240520; 18569328 AB - Soy and red-clover isoflavones are commonly consumed within the diet or as a dietary supplement due to a range of presumed beneficial health benefits. These isoflavones are thought to protect against heart diseases as well as breast and other types of cancer. Isoflavones are structurally similar to estrogens and may act as estrogen agonists or antagonists by binding to estrogen receptors. Because of an increased use of isoflavones in processed foods and dietary supplements as well as the greater consumption of soy products, dietary intakes of isoflavones are increasing in children and adolescents in North America. Estrogens are a known component of numerous hormone related cancers including breast cancer. It is with these facts in mind that we review the existing epidemiological and experimental animal studies for a resolution to a proposed correlation between increased isoflavone consumption and breast cancer. There is conflicting evidence from epidemiological, intervention and experimental animal studies regarding the chemopreventing effects of soy isoflavones in breast cancer. Isoflavones are weak estrogens and their effect depends upon the dose, time of exposure and species involved. It would, therefore, not be safe to indisputably accept soy or red-clover as a source of isoflavone resource to prevent breast cancer. JF - Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews AU - Tomar, Rajpal S AU - Shiao, Renee AD - Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, California 94612, USA. rtomar@oehha.ca.gov PY - 2008 SP - 113 EP - 173 VL - 26 IS - 2 KW - Isoflavones KW - 0 KW - Phytoestrogens KW - Selective Estrogen Receptor Modulators KW - Index Medicus KW - Animals KW - Consumer Product Safety KW - Dose-Response Relationship, Drug KW - Risk Factors KW - Humans KW - Disease Models, Animal KW - Dietary Supplements KW - Time Factors KW - Species Specificity KW - Female KW - Isoflavones -- administration & dosage KW - Soybeans -- chemistry KW - Breast Neoplasms -- prevention & control KW - Isoflavones -- adverse effects KW - Breast Neoplasms -- epidemiology KW - Trifolium -- chemistry KW - Phytoestrogens -- adverse effects KW - Phytoestrogens -- administration & dosage KW - Risk Assessment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69240520?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.atitle=Early+life+and+adult+exposure+to+isoflavones+and+breast+cancer+risk.&rft.au=Tomar%2C+Rajpal+S%3BShiao%2C+Renee&rft.aulast=Tomar&rft.aufirst=Rajpal&rft.date=2008-04-01&rft.volume=26&rft.issue=2&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+science+and+health.+Part+C%2C+Environmental+carcinogenesis+%26+ecotoxicology+reviews&rft.issn=1532-4095&rft_id=info:doi/10.1080%2F10590500802074256 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-10 N1 - Date created - 2008-06-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/10590500802074256 ER - TY - JOUR T1 - Mercury oxidation promoted by a selective catalytic reduction catalyst under simulated Powder River Basin coal combustion conditions. AN - 69118664; 18422035 AB - A bench-scale reactor consisting of a natural gas burner and an electrically heated reactor housing a selective catalytic reduction (SCR) catalyst was constructed for studying elemental mercury (Hg(o)) oxidation under SCR conditions. A low sulfur Powder River Basin (PRB) subbituminous coal combustion fly ash was injected into the entrained-flow reactor along with sulfur dioxide (SO2), nitrogen oxides (NOx), hydrogen chloride (HCl), and trace Hg(o). Concentrations of Hg(o) and total mercury (Hg) upstream and downstream of the SCR catalyst were measured using a Hg monitor. The effects of HCl concentration, SCR operating temperature, catalyst space velocity, and feed rate of PRB fly ash on Hg(o) oxidation were evaluated. It was observed that HCl provides the source of chlorine for Hg(o) oxidation under simulated PRB coal-fired SCR conditions. The decrease in Hg mass balance closure across the catalyst with decreasing HCl concentration suggests that transient Hg capture on the SCR catalyst occurred during the short test exposure periods and that the outlet speciation observed may not be representative of steady-state operation at longer exposure times. Increasing the space velocity and operating temperature of the SCR led to less Hg(o) oxidized. Introduction of PRB coal fly ash resulted in slightly decreased outlet oxidized mercury (Hg2+) as a percentage of total inlet Hg and correspondingly resulted in an incremental increase in Hg capture. The injection of ammonia (NH3) for NOx reduction by SCR was found to have a strong effect to decrease Hg oxidation. The observations suggest that Hg(o) oxidation may occur near the exit region of commercial SCR reactors. Passage of flue gas through SCR systems without NH3 injection, such as during the low-ozone season, may also impact Hg speciation and capture in the flue gas. JF - Journal of the Air & Waste Management Association (1995) AU - Lee, Chun W AU - Serre, Shannon D AU - Zhao, Yongxin AU - Lee, Sung Jun AU - Hastings, Thomas W AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, NC 27711, USA. lee.chun-wai@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 484 EP - 493 VL - 58 IS - 4 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Coal KW - Nitrogen Compounds KW - Sulfur Dioxide KW - 0UZA3422Q4 KW - Sulfur KW - 70FD1KFU70 KW - Mercury KW - FXS1BY2PGL KW - Hydrochloric Acid KW - QTT17582CB KW - Index Medicus KW - Oxidation-Reduction KW - Power Plants KW - Temperature KW - Catalysis KW - Rivers KW - Air Pollution -- prevention & control KW - Mercury -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69118664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Mercury+oxidation+promoted+by+a+selective+catalytic+reduction+catalyst+under+simulated+Powder+River+Basin+coal+combustion+conditions.&rft.au=Lee%2C+Chun+W%3BSerre%2C+Shannon+D%3BZhao%2C+Yongxin%3BLee%2C+Sung+Jun%3BHastings%2C+Thomas+W&rft.aulast=Lee&rft.aufirst=Chun&rft.date=2008-04-01&rft.volume=58&rft.issue=4&rft.spage=484&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-09-17 N1 - Date created - 2008-04-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Great Lakes National Program Office; program introduction and recent initiatives AN - 50533714; 2009-012882 AB - Great Lakes National Program Office: Program Introduction and Emerging Intiatives William (Bill) Bolen, USEPA, Great Lakes National Program Office, Chicago, Illinois This presentation will focus on introducing the audience to the Great Lakes National Program Office (GLNPO) including the Office's Mission Statement, Goals and Objectives, Organizational Structure, and Primary Partnering Agencies. Further detail will be provided specifically on the recent GLNPO initiatives involving the Great Lakes Legacy Act, Remedial Action Plans and Areas of Concern, Rapid Response to Invasive Species, and the utilization of the Lake Guardian for Homeland Security and Response Readiness. JF - Abstracts with Programs - Geological Society of America AU - Bolen, Bill AU - Anonymous Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 30 PB - Geological Society of America (GSA), Boulder, CO VL - 40 IS - 5 SN - 0016-7592, 0016-7592 KW - protection KW - programs KW - North America KW - natural resources KW - Great Lakes region KW - conservation KW - government agencies KW - U. S. Environmental Protection Agency KW - Great Lakes KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50533714?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Great+Lakes+National+Program+Office%3B+program+introduction+and+recent+initiatives&rft.au=Bolen%2C+Bill%3BAnonymous&rft.aulast=Bolen&rft.aufirst=Bill&rft.date=2008-04-01&rft.volume=40&rft.issue=5&rft.spage=30&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, North-Central Section, 42nd annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2009-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - conservation; government agencies; Great Lakes; Great Lakes region; natural resources; North America; programs; protection; U. S. Environmental Protection Agency ER - TY - JOUR T1 - Building model analysis applications with the Joint Universal Parameter IdenTification and Evaluation of Reliability (JUPITER) API AN - 50128353; 2009-098713 AB - The open-source, public domain JUPITER (Joint Universal Parameter IdenTification and Evaluation of Reliability) API (Application Programming Interface) provides conventions and Fortran-90 modules to develop applications (computer programs) for analyzing process models. The input and output conventions allow application users to access various applications and the analysis methods they embody with a minimum of time and effort. Process models simulate, for example, physical, chemical, and (or) biological systems of interest using phenomenological, theoretical, or heuristic approaches. The types of model analyses supported by the JUPITER API include, but are not limited to, sensitivity analysis, data needs assessment, calibration, uncertainty analysis, model discrimination, and optimization. The advantages provided by the JUPITER API for users and programmers allow for rapid programming and testing of new ideas. Application-specific coding can be in languages other than the Fortran-90 of the API. This article briefly describes the capabilities and utility of the JUPITER API, lists existing applications, and uses UCODE_2005 as an example. JF - Computers & Geosciences AU - Banta, Edward R AU - Hill, Mary C AU - Poeter, Eileen AU - Doherty, John E AU - Babendreier, Justin Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 310 EP - 319 PB - Elsevier, Amsterdam VL - 34 IS - 4 SN - 0098-3004, 0098-3004 KW - geology KW - computer programs KW - technology KW - JUPITER Program KW - Joint Universal Parameter IdenTification and Evaluation of Reliability KW - data processing KW - applications KW - simulation KW - 15:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50128353?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Computers+%26+Geosciences&rft.atitle=Building+model+analysis+applications+with+the+Joint+Universal+Parameter+IdenTification+and+Evaluation+of+Reliability+%28JUPITER%29+API&rft.au=Banta%2C+Edward+R%3BHill%2C+Mary+C%3BPoeter%2C+Eileen%3BDoherty%2C+John+E%3BBabendreier%2C+Justin&rft.aulast=Banta&rft.aufirst=Edward&rft.date=2008-04-01&rft.volume=34&rft.issue=4&rft.spage=310&rft.isbn=&rft.btitle=&rft.title=Computers+%26+Geosciences&rft.issn=00983004&rft_id=info:doi/10.1016%2Fj.cageo.2007.03.016 L2 - http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5840&_auth=y&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e5198452fad934c6346f38b57511c8e0 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2009-01-01 N1 - Document feature - illus. incl. 1 table N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - applications; computer programs; data processing; geology; Joint Universal Parameter IdenTification and Evaluation of Reliability; JUPITER Program; simulation; technology DO - http://dx.doi.org/10.1016/j.cageo.2007.03.016 ER - TY - JOUR T1 - Cancer premiums and latency effects: a risk tradeoff approach for valuing reductions in fatal cancer risks AN - 37019645; 3801300 AB - Many studies estimate individuals' values for avoiding fatality risks; however, most value-of-statistical-life studies focus on accident-related deaths. Consequently, little is known about preferences for avoiding other fatal risks, such as cancer. Cancer may engender strong feelings of dread, leading to a 'cancer premium,' but cancer latency periods may have the opposite effect. Using a national survey, we elicit relative preferences for avoiding fatal cancer and auto-accident risks. We find strong preferences for avoiding cancer risks. With a 5-year latency, they are valued roughly three times greater than immediate accident risks, declining to 50% greater for a 25-year latency. Reprinted by permission of Springer JF - Journal of risk and uncertainty AU - Houtven, George Van AU - Sullivan, Melonie B AU - Dockins, Chris AD - RTI International ; Institute for Family Centered Services, Richmond ; US Environmental Protection Agency Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 179 EP - 199 VL - 36 IS - 2 SN - 0895-5646, 0895-5646 KW - Sociology KW - Value theory KW - Survey data KW - Medical research KW - U.S.A. KW - Life expectancy KW - Cancer KW - Risk theory UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37019645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+risk+and+uncertainty&rft.atitle=Cancer+premiums+and+latency+effects%3A+a+risk+tradeoff+approach+for+valuing+reductions+in+fatal+cancer+risks&rft.au=Houtven%2C+George+Van%3BSullivan%2C+Melonie+B%3BDockins%2C+Chris&rft.aulast=Houtven&rft.aufirst=George&rft.date=2008-04-01&rft.volume=36&rft.issue=2&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=Journal+of+risk+and+uncertainty&rft.issn=08955646&rft_id=info:doi/10.1007%2Fs11166-008-9032-2 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 7886 10902; 1939 3617 6220; 11040 11035; 13242 13234 2523 4577 3872 554 971; 7397 8291 3409 6306; 12427 12429; 433 293 14 DO - http://dx.doi.org/10.1007/s11166-008-9032-2 ER - TY - JOUR T1 - Variations in base-flow nitrate flux in a first-order stream and riparian zone AN - 21022294; 8175631 AB - Nonpoint source pollution, which contributes to contamination of surface waters, is difficult to control. Some pollutants, particularly nitrate (NO super(-) sub(3)), are predominantly transmitted through ground water. Riparian buffer zones have the potential to remove contaminants from ground water and reduce the amount of NO super(-) sub(3) that enters surface water. This is a justification for setting aside vegetated buffer strips along waterways. Many riparian zone hydrologic models assume uniform ground-water flow through organic-rich soil under reducing conditions, leading to effective removal of ground-water NO super(-) sub(3) prior to discharge into a stream. However, in a small first-order stream in the mid-Atlantic coastal plain, base-flow generation was highly variable (spatially and temporally). Average base-flow NO super(-) sub(3) loads were greater in winter than summer, and higher during a wetter year than in dryer years. Specific sections of the stream consistently received greater amounts of high NO super(-) sub(3) ground water than others. Areas within the riparian zone responsible for most of the NO super(-) sub(3) exported from the watershed are termed "critical areas." Over this 5-year study, most of the NO super(-) sub(3) exported during base flow originated from a critical area comprising less than 10% of the total riparian zone land area. Allocation of resources to address and improve mitigation function in critical areas should be a priority for continued riparian zone research. JF - Journal of the American Water Resources Association AU - Angier, J T AU - McCarty, G W AD - USDA/ARS-ANRI, Environmental Quality Laboratory, Beltsville Agricultural Research Center-- West, Building 007, Room 214, 10300 Baltimore Avenue, Beltsville, Maryland 20705, USA, Angier.Jonathan@EPA.gov Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 367 EP - 380 VL - 44 IS - 2 SN - 1093-474X, 1093-474X KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Meteorological & Geoastrophysical Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Resource management KW - Surface water KW - buffers KW - Water resources KW - Groundwater Pollution KW - Watersheds KW - Streams KW - Soil KW - mitigation KW - Hydrologic Models KW - Pollutants KW - plains KW - Hydrologic models KW - resource allocation KW - Riparian zone KW - Nitrates KW - Base flow KW - Groundwater flow KW - Nonpoint Pollution Sources KW - River discharge KW - Nonpoint pollution KW - Water pollution KW - winter KW - summer KW - Groundwater pollution KW - Waterways KW - Groundwater KW - M2 556:General (556) KW - SW 3020:Sources and fate of pollution KW - P 1000:MARINE POLLUTION KW - Q2 09171:Dynamics of lakes and rivers KW - AQ 00002:Water Quality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21022294?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Variations+in+base-flow+nitrate+flux+in+a+first-order+stream+and+riparian+zone&rft.au=Angier%2C+J+T%3BMcCarty%2C+G+W&rft.aulast=Angier&rft.aufirst=J&rft.date=2008-04-01&rft.volume=44&rft.issue=2&rft.spage=367&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2007.00153.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Resource management; Nitrates; Pollutants; Riparian zone; River discharge; Groundwater pollution; Water resources; Watersheds; Water pollution; Base flow; Groundwater flow; Hydrologic models; resource allocation; Surface water; buffers; Nonpoint pollution; Streams; Soil; mitigation; winter; summer; plains; Groundwater; Hydrologic Models; Nonpoint Pollution Sources; Groundwater Pollution; Waterways DO - http://dx.doi.org/10.1111/j.1752-1688.2007.00153.x ER - TY - JOUR T1 - The influence of suburban land use on habitat and biotic integrity of coastal Rhode Island streams AN - 21002167; 8168272 AB - Watershed land use in suburban areas can affect stream biota through degradation of instream habitat, water quality, and riparian vegetation. By monitoring stream biotic communities in various geographic regions, we can better understand and conserve our watershed ecosystems. The objective of this study was to examine the relationship between watershed land use and the integrity of benthic invertebrate communities in eight streams that were assessed over a 3-year period (2001-2003). Sites were selected from coastal Rhode Island watersheds along a residential land-use gradient (4-59%). Using the rapid bioassessment protocol, we collected biological, physicochemical, habitat, and nutrient data from wadeable stream reaches and compared metrics of structure and integrity. Principal component analyses showed significant negative correlation of indicators for stream physicochemical, habitat, and instream biodiversity with increasing residential land use (RLU) in the watershed. The physicochemical variables that were most responsive to percent RLU were conductivity, instream habitat, nitrate, and dissolved inorganic nitrogen (DIN). The positive correlation of DIN with percent RLU indicated an anthropogenic source of pollution affecting the streams. The biotic composition of the streams shifted from sensitive to insensitive taxa as percent RLU increased; the most responsive biological variables were percent Ephemeroptera, percent Scrapers, percent Insects, and the Hilsenhoff biotic index. These data show the importance of land management and conservation at the watershed scale to sustaining the biotic integrity of coastal stream ecosystems. JF - Environmental Monitoring and Assessment AU - Lussier, Suzanne M AU - da Silva, Sara N AU - Charpentier, Michael AU - Heltshe, James F AU - Cormier, Susan M AU - Klemm, Donald J AU - Chintala, Marnita AU - Jayaraman, Saro AD - U.S. Environmental Protection Agency, 27 Tarzwell Drive, Narragansett, RI, 02882, USA, lussier.suzanne@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 119 EP - 136 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de] VL - 139 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Pollution Abstracts; Ecology Abstracts; Entomology Abstracts; Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - water quality KW - Pollution monitoring KW - Resource management KW - Ecosystems KW - Biological diversity KW - Biodiversity KW - insects KW - Watersheds KW - Streams KW - invertebrates KW - Biota KW - Ephemeroptera KW - Aquatic insects KW - Pollution KW - Environmental monitoring KW - Nitrates KW - principal components analysis KW - Habitat KW - Land use KW - Conservation KW - Zoobenthos KW - Nitrogen KW - D 04070:Pollution KW - Z 05340:Ecology and Behavior KW - M3 1010:Issues in Sustainable Development KW - Q2 09184:Composition of water KW - P 1000:MARINE POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21002167?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=The+influence+of+suburban+land+use+on+habitat+and+biotic+integrity+of+coastal+Rhode+Island+streams&rft.au=Lussier%2C+Suzanne+M%3Bda+Silva%2C+Sara+N%3BCharpentier%2C+Michael%3BHeltshe%2C+James+F%3BCormier%2C+Susan+M%3BKlemm%2C+Donald+J%3BChintala%2C+Marnita%3BJayaraman%2C+Saro&rft.aulast=Lussier&rft.aufirst=Suzanne&rft.date=2008-04-01&rft.volume=139&rft.issue=1-3&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-007-9820-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Pollution monitoring; Resource management; Biodiversity; Habitat; Zoobenthos; Watersheds; Aquatic insects; Land use; Streams; Pollution; Nitrogen; water quality; Ecosystems; Nitrates; principal components analysis; Biological diversity; insects; invertebrates; Biota; Conservation; Ephemeroptera DO - http://dx.doi.org/10.1007/s10661-007-9820-1 ER - TY - JOUR T1 - Fecal source tracking by antibiotic resistance analysis on a watershed exhibiting low resistance AN - 20961584; 8168263 AB - The ongoing development of microbial source tracking has made it possible to identify contamination sources with varying accuracy, depending on the method used. The purpose of this study was to test the efficiency of the antibiotic resistance analysis (ARA) method under low resistance by tracking the fecal sources at Turkey Creek, Oklahoma exhibiting this condition. The resistance patterns of 772 water-isolates, tested with nine antibiotics, were analyzed by discriminant analysis (DA) utilizing a five-source library containing 2250 isolates. The library passed various representativeness tests; however, two of the pulled-sample tests suggested insufficient sampling. The resubstitution test of the library individual sources showed significant isolate misclassification with an average rate of correct classification (ARCC) of 58%. These misclassifications were explained by low antibiotic resistance (Wilcoxon test P < 0.0001). Seasonal DA of stream E. coli isolates for the pooled sources human/livestock/deer indicated that in fall, the human source dominated (P < 0.0001) at a rate of 56%, and that human and livestock respective contributions in winter (35 and 39%), spring (43 and 40%), and summer (37 and 35%) were similar. Deer scored lower (17-28%) than human and livestock at every season. The DA was revised using results from a misclassification analysis to provide a perspective of the effect caused by low antibiotic resistance and a more realistic determination of the fecal source rates at Turkey Creek. The revision increased livestock rates by 13-14% (0.04 less than or equal to P less than or equal to 0.06), and decreased human and deer by 6-7%. Negative misclassification into livestock was significant (0.04 less than or equal to P less than or equal to 0.06). Low antibiotic resistance showed the greatest effect in this category. JF - Environmental Monitoring and Assessment AU - Olivas, Yolanda AU - Faulkner, Barton R AD - P.O. BOX 1198, Ada, OK, 74820, USA, olivas.yolanda@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 15 EP - 25 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de] VL - 139 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Pollution Abstracts; Microbiology Abstracts B: Bacteriology; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts KW - Contamination KW - Antibiotics KW - Microbial contamination KW - Watersheds KW - Dopamine KW - Resistance KW - Classification KW - Libraries KW - Escherichia coli KW - Seasonal variability KW - Seasonal variations KW - Antibiotic resistance KW - deer KW - Testing Procedures KW - Environmental monitoring KW - Pathogenic bacteria KW - Control resistance KW - winter KW - Monitoring KW - antibiotic resistance KW - Streams KW - USA, Oklahoma KW - Sulfur dioxide KW - Meteorological literature KW - Water springs KW - Sampling KW - Deer KW - Tracking KW - Livestock KW - summer KW - Environmental conditions KW - Q5 08503:Characteristics, behavior and fate KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution KW - M2 551.5:General (551.5) KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20961584?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=Fecal+source+tracking+by+antibiotic+resistance+analysis+on+a+watershed+exhibiting+low+resistance&rft.au=Olivas%2C+Yolanda%3BFaulkner%2C+Barton+R&rft.aulast=Olivas&rft.aufirst=Yolanda&rft.date=2008-04-01&rft.volume=139&rft.issue=1-3&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-007-9805-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Pathogenic bacteria; Classification; Antibiotics; Microbial contamination; Environmental conditions; Watersheds; Tracking; Control resistance; Dopamine; Contamination; Sampling; Streams; Antibiotic resistance; Livestock; Meteorological literature; Seasonal variability; winter; Sulfur dioxide; antibiotic resistance; Water springs; summer; Seasonal variations; deer; Testing Procedures; Resistance; Libraries; Monitoring; Deer; Escherichia coli; USA, Oklahoma DO - http://dx.doi.org/10.1007/s10661-007-9805-0 ER - TY - JOUR T1 - Dietary Uptake Models Used for Modeling the Bioaccumulation of Organic Contaminants in Fish AN - 20898327; 8188733 AB - Numerous models have been developed to predict the bioaccumulation of organic chemicals in fish. Although chemical dietary uptake can be modeled using assimilation efficiencies, bioaccumulation models fall into two distinct groups. The first group implicitly assumes that assimilation efficiencies describe the net chemical exchanges between fish and their food. These models describe chemical elimination as a lumped process that is independent of the fish's egestion rate or as a process that does not require an explicit fecal excretion term. The second group, however, explicitly assumes that assimilation efficiencies describe only actual chemical uptake and formulates chemical fecal and gill excretion as distinct, thermodynamically driven processes. After reviewing the derivations and assumptions of the algorithms that have been used to describe chemical dietary uptake of fish, their application, as implemented in 16 published bioaccumulation models, is analyzed for largemouth bass (Micropterus salmoides), walleye (Sander vitreus = Stizostedion vitreum), and rainbow trout (Oncorhynchus mykiss) that bioaccumulate an unspecified, poorly metabolized, hydrophobic chemical possessing a log K sub(OW) of 6.5 (i.e., a chemical similar to a pentachlorobiphenyl). JF - Environmental Toxicology and Chemistry AU - Barber, MCraig AD - Ecosystems Research Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, 960 College Station Road, Athens, Georgia 30605-2700 Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 755 EP - 777 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 27 IS - 4 SN - 0730-7268, 0730-7268 KW - Pollution Abstracts; Toxicology Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Bioaccumulation KW - Model KW - Dietary uptake KW - Assimilation efficiencies KW - Fish KW - Chemicals KW - Micropterus salmoides KW - Food KW - Algorithms KW - Hydrophobicity KW - Freshwater fish KW - Marine fish KW - Absorption KW - PCB KW - Toxicology KW - Gills KW - Modelling KW - Salmon KW - Diets KW - Geochemistry KW - Oncorhynchus mykiss KW - Stizostedion vitreum KW - Model Studies KW - Foods KW - Trout KW - walleye KW - Excretion KW - Contaminants KW - Q5 08503:Characteristics, behavior and fate KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - Q1 08425:Nutrition and feeding habits KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20898327?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=Dietary+Uptake+Models+Used+for+Modeling+the+Bioaccumulation+of+Organic+Contaminants+in+Fish&rft.au=Barber%2C+MCraig&rft.aulast=Barber&rft.aufirst=MCraig&rft.date=2008-04-01&rft.volume=27&rft.issue=4&rft.spage=755&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F07-462.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Marine fish; Bioaccumulation; Geochemistry; Excretion; Freshwater fish; Gills; Toxicology; Modelling; Food; Algorithms; Hydrophobicity; Contaminants; PCB; Diets; Chemicals; Salmon; Foods; Trout; Absorption; walleye; Model Studies; Micropterus salmoides; Oncorhynchus mykiss; Stizostedion vitreum DO - http://dx.doi.org/10.1897/07-462.1 ER - TY - JOUR T1 - Modeling urban and regional aerosols-Application of the CMAQ-UCD Aerosol Model to Tampa, a coastal urban site AN - 20896101; 8186010 AB - The University of California at Davis (UCD) aerosol module, an internally mixed, sectional aerosol model with dynamic mass transfer between the gas and particle phases, has been coupled to the Community Multiscale Air Quality (CMAQ) model. This paper describes the application of the CMAQ-UCD model to simulate air quality in Tampa, a large city with a population of 2M on the west coast of Florida, USA. Modeled aerosol size and composition distributions are evaluated against size-segregated ambient measurements of SO sub(4) super(2) super(-), NH sub(4) super(+), NO sub(3) super(-), Na super(+), and Cl super(-) collected at three Tampa-area sites during May 2002, and against semi-continuous HNO sub(3) and total aerosol SO sub(4) super(2) super(-), NH sub(4) super(+), NO sub(3) super(-), and Cl super(-) measurements collected at a single site. Sea-salt emissions over the open ocean and the surf zone are parameterized as a function of modeled wind speed and relative humidity. Modeled total aerosol sulfate and ammonium concentrations and size distributions agree with measurements, with an overall normalized mean bias (NMB) of 2% and -23% and normalized mean error (NME) of 46% and 38%, respectively, and correctly identifying the size bin in which the peak concentration is observed. Sea-salt size distributions are also simulated well, with the distribution dominated by the coarse mode and total aerosol sodium and chloride NMB of -2% and 17% and NME of 32% and 38%. Though the model correctly identifies that nitrate is predominantly in the coarse (D sub(p)>2.5 mu m) size sections, aerosol nitrate concentrations are underpredicted by a factor of two. The availability of highly time-resolved measurements provides a unique opportunity to evaluate the model's partitioning of total nitrate and the simulation of chloride depletion as a function of particle size. JF - Atmospheric Environment AU - Nolte, C G AU - Bhave, P V AU - Arnold, J R AU - Dennis, R L AU - Zhang, K M AU - Wexler, A S AD - Air Resources Laboratory, National Oceanic and Atmospheric Administration, Research Triangle Park, NC, USA, nolte.chris@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 3179 EP - 3191 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 42 IS - 13 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts KW - Relative humidity KW - Atmospheric pollution models KW - Aerosol models KW - Chlorides KW - Air quality KW - Particulates KW - Wind speed KW - Emission measurements KW - Emissions KW - Body size KW - Urban areas KW - Modelling KW - Ammonium compounds KW - Particle size KW - Aerosols KW - Atmospheric pollution KW - Nitrates KW - ASW, USA, Florida, Tampa KW - Velocity KW - Simulation KW - Humidity KW - Sodium KW - Coastal zone KW - Numerical simulations KW - USA, California, Davis KW - Oceans KW - INE, USA, West Coast KW - Mass transfer KW - Size distribution KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - Q5 08501:General KW - O 2050:Chemical Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20896101?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Modeling+urban+and+regional+aerosols-Application+of+the+CMAQ-UCD+Aerosol+Model+to+Tampa%2C+a+coastal+urban+site&rft.au=Nolte%2C+C+G%3BBhave%2C+P+V%3BArnold%2C+J+R%3BDennis%2C+R+L%3BZhang%2C+K+M%3BWexler%2C+A+S&rft.aulast=Nolte&rft.aufirst=C&rft.date=2008-04-01&rft.volume=42&rft.issue=13&rft.spage=3179&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.12.059 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Particle size; Relative humidity; Coastal zone; Aerosols; Body size; Mass transfer; Size distribution; Ammonium compounds; Modelling; Wind speed; Atmospheric pollution; Atmospheric pollution models; Numerical simulations; Aerosol models; Air quality; Nitrates; Chlorides; Humidity; Simulation; Velocity; Particulates; Sodium; Oceans; Emissions; Emission measurements; Urban areas; USA, California, Davis; INE, USA, West Coast; ASW, USA, Florida, Tampa DO - http://dx.doi.org/10.1016/j.atmosenv.2007.12.059 ER - TY - JOUR T1 - Understanding of hydraulic properties from configurations of stochastically distributed fracture networks AN - 20863112; 8235707 AB - A systematic investigation of the effect of configurations of stochastically distributed fracture networks on hydraulic behaviour for fractured rock masses could provide either quantitative or qualitative correlation between the structural configuration of the fracture network and its corresponding hydraulic behaviour, and enhance our understanding of appropriate application of groundwater flow and contaminant transport modelling in fractured rock masses. In this study, the effect of block sizes, intersection angles of fracture sets, standard deviations of fracture orientation, and fracture densities on directional block hydraulic conductivity and representative elementary volume is systematically investigated in two dimensions by implementing a numerical discrete fracture fluid flow model and incorporating stochastically distributed fracture configurations. It is shown from this investigation that the configuration of a stochastically distributed fracture network has a significant quantitative or qualitative effect on the hydraulic behaviour of fractured rock masses. Compared with the deterministic fracture configurations that have been extensively dealt with in a previous study, this investigation is expected to be more practical and adequate, since fracture geometry parameters are inherently stochastically distributed in the field. Moreover, the methodology and approach presented in this study may be generally applied to any fracture system in investigating the hydraulic behaviours from configurations of the fracture system while establishing a bridge from the discrete fracture network flow modelling to equivalent continuum modelling in fractured rock masses. JF - Hydrological Processes AU - Wang, Mingyu AU - Kulatilake, P H S W AD - Center for Subsurface Modeling Support, US EPA Robert S. Kerr Environmental Research Center, 919 Kerr Research Dr., Ada, OK 74820, USA,; wang.mingyu@epa.gov] mingyuwpan@yahoo.com Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 1125 EP - 1135 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk], [URL:http://www.wiley.com/] VL - 22 IS - 8 SN - 0885-6087, 0885-6087 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts KW - Hydraulic conductivity KW - Geologic Fractures KW - Hydraulics KW - Hydrologic analysis KW - Density KW - Groundwater flow KW - Correlations KW - Hydrologic Models KW - Pollutants KW - Standard Deviation KW - Networks KW - Groundwater Movement KW - Fluid flow KW - Hydraulic Properties KW - M2 556.38:Groundwater Basins (556.38) KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20863112?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Hydrological+Processes&rft.atitle=Understanding+of+hydraulic+properties+from+configurations+of+stochastically+distributed+fracture+networks&rft.au=Wang%2C+Mingyu%3BKulatilake%2C+P+H+S+W&rft.aulast=Wang&rft.aufirst=Mingyu&rft.date=2008-04-01&rft.volume=22&rft.issue=8&rft.spage=1125&rft.isbn=&rft.btitle=&rft.title=Hydrological+Processes&rft.issn=08856087&rft_id=info:doi/10.1002%2Fhyp.6667 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Hydraulic conductivity; Hydrologic analysis; Groundwater flow; Correlations; Fluid flow; Hydraulics; Geologic Fractures; Hydrologic Models; Standard Deviation; Pollutants; Density; Networks; Groundwater Movement; Hydraulic Properties DO - http://dx.doi.org/10.1002/hyp.6667 ER - TY - JOUR T1 - The potential for monolayers to reduce the evaporation of water from large water storages AN - 20851547; 8254447 AB - In the laboratory, molecularly thick films of compounds such as hexadecanol and octadecanol have been shown to retard the evaporation of water. While such monolayers offer the prospect of an economical solution to the evaporative loss of water from storages there are practical difficulties arising mainly from the short lifetimes of these monolayers on the water surface. This review article describes the relevant laboratory experiments and results, and then discusses the problems that have arisen in field applications. It is clear that better monolayer materials are required and that better methods of monolayer distribution would also be helpful. Although no resolution of these difficulties is available at present it is hoped that a better understanding of the problems will stimulate further research. JF - Agricultural Water Management AU - Barnes, G T AD - National Centre for Engineering in Agriculture (NCEA), The University of Southern Queensland, Toowoomba, Queensland 4350, Australia, g.barnes@uq.edu.au Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 339 EP - 353 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 95 IS - 4 SN - 0378-3774, 0378-3774 KW - Water Resources Abstracts; Meteorological & Geoastrophysical Abstracts KW - Water Management KW - Evaporation KW - Laboratories KW - Water storage KW - Storage KW - Water management KW - Evaporation Control KW - Reviews KW - Water Storage KW - Laboratory experiments KW - Films KW - M2 556.13:Evaporation/Evapotranspiration (556.13) KW - SW 7060:Research facilities UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20851547?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Agricultural+Water+Management&rft.atitle=The+potential+for+monolayers+to+reduce+the+evaporation+of+water+from+large+water+storages&rft.au=Barnes%2C+G+T&rft.aulast=Barnes&rft.aufirst=G&rft.date=2008-04-01&rft.volume=95&rft.issue=4&rft.spage=339&rft.isbn=&rft.btitle=&rft.title=Agricultural+Water+Management&rft.issn=03783774&rft_id=info:doi/10.1016%2Fj.agwat.2007.12.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Laboratories; Reviews; Evaporation; Water Management; Storage; Films; Water Storage; Evaporation Control; Laboratory experiments; Water storage; Water management DO - http://dx.doi.org/10.1016/j.agwat.2007.12.003 ER - TY - JOUR T1 - Species action plans for threatened species in Sweden AN - 20804662; 10919116 AB - In cooperation with government agencies and the Swedish Species Information Centre, Per S-G was project leader designing the work with national species action plans (NAPs; or "recovery plans") for threatened species in Sweden 2004-2010. Seven interim targets of environmental quality objectives adopted by the Swedish Parliament explicitly address threatened species, and six of them NAPs to be introduced no later than in 2005-2006. Four of these six targets were achieved on time: i.e. for species in limnic environments, wetlands, forests, and in the agricultural landscape. Those for threatened species in montaneous environments and marine+coastal habitats, respectively, were not achieved on time. The seventh interim target states that due to improved conservation status, the fraction of red-listed species classified as threatened in 2015 is at least 30% smaller than in yr 2000. In total between 219 and 270 NAPs are needed. JF - Entomologisk Tidskrift AU - Ehnstroem, B AU - Sjoegrn-Gulve, P AD - The Swedish Environmental Protection Agency, Dept of Natural Resources, SE-106 48 Stockholm, Sweden, per.sjogren-gulve@naturvardsverket.se Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 210 VL - 129 IS - 4 SN - 0013-886X, 0013-886X KW - Entomology Abstracts; Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Cooperation KW - Landscape KW - Information centres KW - Forests KW - agricultural land KW - Rare species KW - Habitat KW - threatened species KW - Planning KW - Nature conservation KW - Conservation KW - Environmental quality KW - Wetlands KW - Governments KW - Sweden KW - Government agencies KW - Q1 08463:Habitat community studies KW - Z 05340:Ecology and Behavior KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20804662?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Entomologisk+Tidskrift&rft.atitle=Species+action+plans+for+threatened+species+in+Sweden&rft.au=Ehnstroem%2C+B%3BSjoegrn-Gulve%2C+P&rft.aulast=Ehnstroem&rft.aufirst=B&rft.date=2008-04-01&rft.volume=129&rft.issue=4&rft.spage=210&rft.isbn=&rft.btitle=&rft.title=Entomologisk+Tidskrift&rft.issn=0013886X&rft_id=info:doi/ LA - Swedish DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Planning; Information centres; Nature conservation; Governments; Wetlands; Rare species; Cooperation; Landscape; Environmental quality; Forests; Conservation; Habitat; threatened species; agricultural land; Government agencies; Sweden ER - TY - JOUR T1 - Alien species importance in native vegetation along wadeable streams, John Day River basin, Oregon, USA AN - 20690824; 8170254 AB - We evaluated the importance of alien species in existing vegetation along wadeable streams of a large, topographically diverse river basin in eastern Oregon, USA; sampling 165 plots (30 x 30 m) across 29 randomly selected 1-km stream reaches. Plots represented eight streamside community types associated with varying elevation, precipitation, and landform. Mantel comparisons, non-metric multidimensional scaling (NMS), and Spearman correlation identified relationships of alien species (n = 60) distribution and relative alien cover (RAC) to native species (n = 355) composition, 28 vegetation descriptors, 31 environmental variables, and 30 disturbance conditions. Alien species occurred in 93% of sample plots, in all community types, and along all sampled stream reaches; with RAC ranging from 0.1% to 47% and 1 to 24 alien species occurring along individual stream reaches. Alien richness and RAC were positively related to native diversity where invasion was limited (RAC 5%). RAC differed among community types: greatest in arid associations (shrubland/grassland), followed by associations with limited tree canopy cover (meadows, dry forest), and lowest in moist, closed forest associations; suggesting differences in invasion status or vulnerabilities to alien invasion among community types. Alien species, as a group had wider ecological amplitude than natives, and species composition among community types was less distinct when both alien and natives were considered compared to native species only. RAC was negatively related to elevation, precipitation, and tree cover; while positive relationships of RAC occurred with grazing pressure, upstream watershed size, stream order, overall level of exogenous disturbance, limited vegetated buffer, agriculture in the upstream watershed, floodplain or south facing slope locations, and proximity to roads. Taken together, these results suggest possible ecological consequences to streamside vegetation related to alien species and identify indicators of conditions, where invasion may be greatest, offering potential for informing decisions for monitoring and managing alien species. JF - Plant Ecology AU - Magee, Teresa K AU - Ringold, Paul L AU - Bollman, Michael A AD - Dynamac Corporation, 200 SW 35th Street, Corvallis, OR, 97333, USA, magee.teresa@epa.gov Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 287 EP - 307 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 195 IS - 2 SN - 1385-0237, 1385-0237 KW - Ecology Abstracts; Water Resources Abstracts KW - River Basins KW - Trees KW - Vegetation KW - River basins KW - Precipitation KW - Watersheds KW - Streams KW - Indigenous species KW - Grasslands KW - Meadows KW - Elevation KW - USA, Oregon KW - Scaling KW - SW 0835:Streamflow and runoff KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20690824?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Ecology&rft.atitle=Alien+species+importance+in+native+vegetation+along+wadeable+streams%2C+John+Day+River+basin%2C+Oregon%2C+USA&rft.au=Magee%2C+Teresa+K%3BRingold%2C+Paul+L%3BBollman%2C+Michael+A&rft.aulast=Magee&rft.aufirst=Teresa&rft.date=2008-04-01&rft.volume=195&rft.issue=2&rft.spage=287&rft.isbn=&rft.btitle=&rft.title=Plant+Ecology&rft.issn=13850237&rft_id=info:doi/10.1007%2Fs11258-007-9330-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Streams; Vegetation; Watersheds; River Basins; Trees; Elevation; Precipitation; Scaling; Grasslands; USA, Oregon; River basins; Indigenous species; Meadows DO - http://dx.doi.org/10.1007/s11258-007-9330-9 ER - TY - JOUR T1 - The link between international trade and the global distribution of invasive alien species AN - 20658430; 8167832 AB - Invasive alien species (IAS) exact large biodiversity and economic costs and are a significant component of human-induced, global environmental change. Previous studies looking at the variation in alien species across regions have been limited geographically or taxonomically or have not considered economics. We used a global invasive species database to regress IAS per-country on a suite of socioeconomic, ecological, and biogeographical variables. We varied the countries included in the regression tree analyses, in order to explore whether certain outliers were biasing the results, and in most of the cases, merchandise imports was the most important explanatory variable. The greater the degree of international trade, the higher the number of IAS. We also found a positive relationship between species richness and the number of invasives, in accord with other investigations at large spatial scales. Island status (overall), country area, latitude, continental position (New World versus Old World) or other measures of human disturbance (e.g., GDP per capita, population density) were not found to be important determinants of a country's degree of biological invasion, contrary to previous studies. Our findings also provide support to the idea that more resources for combating IAS should be directed at the introduction stage and that novel trade instruments need to be explored to account for this environmental externality. JF - Biological Invasions AU - Westphal, Michael I AU - Browne, Michael AU - MacKinnon, Kathy AU - Noble, Ian AD - Office of International Affairs, United States Environmental Protection Agency, Washington, DC, 20460, USA, mwestphal@worldbank.org Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 391 EP - 398 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 10 IS - 4 SN - 1387-3547, 1387-3547 KW - Sustainability Science Abstracts; Ecology Abstracts KW - Population density KW - Biodiversity KW - Islands KW - GDP KW - Economics KW - Invasions KW - Introduced species KW - Species richness KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20658430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Invasions&rft.atitle=The+link+between+international+trade+and+the+global+distribution+of+invasive+alien+species&rft.au=Westphal%2C+Michael+I%3BBrowne%2C+Michael%3BMacKinnon%2C+Kathy%3BNoble%2C+Ian&rft.aulast=Westphal&rft.aufirst=Michael&rft.date=2008-04-01&rft.volume=10&rft.issue=4&rft.spage=391&rft.isbn=&rft.btitle=&rft.title=Biological+Invasions&rft.issn=13873547&rft_id=info:doi/10.1007%2Fs10530-007-9138-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Economics; Invasions; Population density; Species richness; Islands; GDP; Introduced species; Biodiversity DO - http://dx.doi.org/10.1007/s10530-007-9138-5 ER - TY - JOUR T1 - Parametric distance weighting of landscape influence on streams AN - 20623486; 8169516 AB - We present a parametric model for estimating the areas within watersheds whose land use best predicts indicators of stream ecological condition. We regress a stream response variable on the distance-weighted proportion of watershed area that has a specific land use, such as agriculture. Distance weighting functions model the declining influence of landscape elements as a function of their flowpath distances, first to the stream channel (to-stream distance), and then down the channel to the location at which stream condition was sampled (in-stream distance). Model parameters specify different distance scales over which to-stream and in-stream influences decline. As an example, we predict an index of biotic integrity (IBI) for the fish communities in 50 small streams of the Willamette Basin of Oregon, USA, from distance-weighted proportions of agricultural or urban land use in their watersheds. The weighting functions of best-fitting models (R super(2) = 0.57) represent landscape influence on IBI as extending upstream tens of kilometers along the stream channel network, while declining nearly to zero beyond a distance of 30 m from the channel. Our example shows how parametric distance weighting can identify the distance scales, and hence the approximate areas within watersheds, for which land use is most strongly associated with a stream response variable. In addition, distance-weighting parameters offer a simple and direct language for comparing the scales of landscape influence on streams across different land uses and stream ecosystem components. JF - Landscape Ecology AU - Van Sickle, John AU - Burch Johnson, Colleen AD - U.S. Environmental Protection Agency, 200 SW 35th St., Corvallis, OR, 97333, USA, VanSickle.John@epa.gov Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 427 EP - 438 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 23 IS - 4 SN - 0921-2973, 0921-2973 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Sustainability Science Abstracts; Ecology Abstracts KW - Land Use KW - Ecosystems KW - Indicators KW - Basins KW - Freshwater KW - Watersheds KW - Streams KW - Models KW - Networks KW - Landscape KW - River discharge KW - Land use KW - Model Studies KW - Channels KW - INE, USA, Oregon KW - Scales KW - Language KW - Fish Populations KW - AQ 00001:Water Resources and Supplies KW - SW 5010:Network design KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - Q2 09171:Dynamics of lakes and rivers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20623486?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Landscape+Ecology&rft.atitle=Parametric+distance+weighting+of+landscape+influence+on+streams&rft.au=Van+Sickle%2C+John%3BBurch+Johnson%2C+Colleen&rft.aulast=Van+Sickle&rft.aufirst=John&rft.date=2008-04-01&rft.volume=23&rft.issue=4&rft.spage=427&rft.isbn=&rft.btitle=&rft.title=Landscape+Ecology&rft.issn=09212973&rft_id=info:doi/10.1007%2Fs10980-008-9200-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-08-19 N1 - SubjectsTermNotLitGenreText - River discharge; Watersheds; Land use; Scales; Landscape; Basins; Language; Streams; Models; Channels; Land Use; Ecosystems; Indicators; Networks; Fish Populations; Model Studies; INE, USA, Oregon; Freshwater DO - http://dx.doi.org/10.1007/s10980-008-9200-4 ER - TY - JOUR T1 - Estuarine Phytoplankton Responses to Hurricanes and Tropical Storms with Different Characteristics (Trajectory, Rainfall, Winds) AN - 20620275; 9321543 AB - We examined the short-term (<1 month post-storm) impact of storms [Tropical Storm (TS) Helene in 2000, Hurricane (H) Isabel in 2003, H Alex, Tropical Depression (TD) Bonnie and TS Charley in 2004] varying in their trajectory, wind and rainfall characteristics, on water column structure, nutrients, and phytoplankton biomass in North Carolina's Neuse R. Estuary (NRE). Data are presented from two sampling programs, ModMon (biweekly) and FerryMon (measurements made every 3 min daily). Helene's winds mixed the previously stratified water column, delivering sediment-bound nutrients to the euphotic zone, and localized freshwater input from Helene was also evident. Mean chlorophyll a concentrations in the mesohaline portion of the NRE, where N was strongly limiting before the storm (molar DIN:DIP < 1), more than doubled after the storm. Unlike with Helene, the water column was well mixed before passage of Isabel, and nutrient concentrations were high. As a result, minimal impact on phytoplankton biomass was detected despite Isabel's high winds and significant freshwater input. In fact, conditions became less favorable for phytoplankton growth after the storm. Alex was fast moving and relatively small, but its winds were sufficient to mix the water column. Although data from ModMon suggest that chlorophyll a was only slightly higher after passage of Alex, FerryMon detected an ephemeral bloom that was missed by ModMon. Overall, these results suggest that relatively small tropical storms and hurricanes can lead to significant increases in phytoplankton biomass. However, the phytoplankton response depends on both the characteristics of a particular storm and the physical-chemical conditions of the water column before storm passage. Finally, the ephemeral bloom that developed as a result of Alex, the strong response of phytoplankton in the mesohaline portion of the estuary to nutrient inputs, and their patchiness on several other occasions suggests that storms may create "hot spots" for trophic transfer and biogeochemical dynamics in estuaries. Adaptive sampling is necessary to capture these features and to fully understand the impact of perturbations such as storms on estuarine ecosystem functioning. JF - Estuaries and Coasts AU - Wetz, Michael S AU - Paerl, Hans W AD - Environmental Sciences Division, U.S. Environmental Protection Agency, Research Triangle Park, Durham, NC 27711, USA, wetz@email.unc.edu Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 419 EP - 429 PB - Estuarine Research Federation, 490 Chippingwood Dr. No. 2 Port Republic MD 20676-2140 USA VL - 31 IS - 2 SN - 1559-2723, 1559-2723 KW - Ecology Abstracts; Aqualine Abstracts; Water Resources Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Meteorological & Geoastrophysical Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 1: Biological Sciences & Living Resources KW - Phytoplankton KW - Estuary KW - Storms KW - Nutrients KW - Mixing KW - Freshwater input KW - Chlorophylls KW - Algal blooms KW - Chlorophyll KW - Hot spots KW - Rainfall KW - Water column KW - Wind KW - Depression KW - Freshwater environments KW - Estuaries KW - Brackish KW - Biomass KW - Tropical depressions KW - Nutrient concentrations KW - Growth KW - Brackishwater environment KW - Sampling KW - Coasts KW - ANW, USA, North Carolina KW - Euphotic zone KW - Data processing KW - Hurricanes KW - O 1070:Ecology/Community Studies KW - AQ 00001:Water Resources and Supplies KW - M2 551.468:Coastal Oceanography (551.468) KW - D 04040:Ecosystem and Ecology Studies KW - Q2 09261:General KW - Q1 08481:Productivity KW - SW 0815:Precipitation KW - K 03320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20620275?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuaries+and+Coasts&rft.atitle=Estuarine+Phytoplankton+Responses+to+Hurricanes+and+Tropical+Storms+with+Different+Characteristics+%28Trajectory%2C+Rainfall%2C+Winds%29&rft.au=Wetz%2C+Michael+S%3BPaerl%2C+Hans+W&rft.aulast=Wetz&rft.aufirst=Michael&rft.date=2008-04-01&rft.volume=31&rft.issue=2&rft.spage=419&rft.isbn=&rft.btitle=&rft.title=Estuaries+and+Coasts&rft.issn=15592723&rft_id=info:doi/10.1007%2Fs12237-008-9034-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Algal blooms; Chlorophylls; Hurricanes; Growth; Estuaries; Brackishwater environment; Phytoplankton; Biomass; Tropical depressions; Euphotic zone; Chlorophyll; Depression; Data processing; Hot spots; Freshwater environments; Rainfall; Nutrients; Water column; Sampling; Nutrient concentrations; Wind; Coasts; Storms; ANW, USA, North Carolina; Brackish DO - http://dx.doi.org/10.1007/s12237-008-9034-y ER - TY - JOUR T1 - Neurobehavioral toxicology of pyrethroid insecticides in adult animals: A critical review AN - 20571163; 8093572 AB - Pyrethroids are pesticides with high selectivity for insects. In order to identify strengths and gaps in the database for pyrethroid neurobehavioral toxicology, we have critically analyzed the data from peer-reviewed literature. This review includes dose-response data that have been recently generated demonstrating consistent findings for low-dose, acute, oral exposure to pyrethroids in small rodents. All pyrethroids tested (i.e., about twenty compounds), regardless of structure, produce a decrease in motor activity in a variety of test protocols. The range of relative potencies varies more than two orders of magnitude, and thresholds for motor activity were found well below doses that produce overt signs of poisoning. Six compounds (allethrin, permethrin, cis-permethrin, deltamethrin, cypermethrin, and fenvalerate) impair schedule-controlled operant responding, seven compounds (pyrethrum, bifenthrin, S-bioallethrin, permethrin, beta -cyfluthrin, cypermethrin, and deltamethrin) decrease grip strength, and two compounds (deltamethrin and alpha -cypermethrin) produce incoordination using the rotarod. In addition, while compounds lacking an alpha -cyano group (e.g., cismethrin, permethrin, bifenthrin) induce an increase in acoustic-evoked startle response amplitude, cyano compounds (e.g., deltamethrin, cypermethrin, cyfluthrin) produce the opposite outcome. Other endpoints (e.g., tremor intensity, sensory response) have been only occasionally explored. A synthesis of the neurobehavioral evidence relating to the action of pyrethroids indicates that some differences in the experimental findings across compounds are also present in the low-effective dose range. For risk assessment purposes, a strategy that takes into account data from an array of neurobehavioral endpoints is needed to capture the heterogeneity of pyrethroid-induced adverse effects and accurately inform policy decisions. JF - Neurotoxicology and Teratology AU - Wolansky, MJ AU - Harrill, JA AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, USEPA, RTP, NC, United States, mjwolansky@gmail.com Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 55 EP - 78 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 30 IS - 2 SN - 0892-0362, 0892-0362 KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - Risk assessment KW - Data processing KW - Fenvalerate KW - Cypermethrin KW - Operant conditioning KW - Poisoning KW - Permethrin KW - Deltamethrin KW - Databases KW - Startle response KW - Insecticides KW - Reviews KW - Motor activity KW - Pesticides KW - tremor KW - Pyrethroids KW - Side effects KW - N3 11028:Neuropharmacology & toxicology KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20571163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Neurobehavioral+toxicology+of+pyrethroid+insecticides+in+adult+animals%3A+A+critical+review&rft.au=Wolansky%2C+MJ%3BHarrill%2C+JA&rft.aulast=Wolansky&rft.aufirst=MJ&rft.date=2008-04-01&rft.volume=30&rft.issue=2&rft.spage=55&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2007.10.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Fenvalerate; Data processing; Operant conditioning; Cypermethrin; Poisoning; Permethrin; Deltamethrin; Databases; Insecticides; Startle response; Motor activity; Reviews; Pesticides; Pyrethroids; tremor; Side effects DO - http://dx.doi.org/10.1016/j.ntt.2007.10.005 ER - TY - JOUR T1 - Acute postnatal exposure to brominated diphenylether 47 delays neuromotor ontogeny and alters motor activity in mice AN - 20568144; 8093210 AB - Polybrominated diphenyl ethers (PBDEs) are widely used commercial flame retardants that are accumulating in the environment. PBDEs may interfere with the development of key biological systems, thus leaving children vulnerable to functional impairments in adulthood. There is a growing literature of animal studies that show subtle changes in motor and cognitive function following acute or repeated perinatal exposure to PBDEs. 2,2',4,4'-Brominated diphenyl ether (BDE 47), a very stable PBDE congener, has been shown to accumulate in humans, perhaps as a breakdown product of other PBDEs. The current study examined developmental milestones in male C57BL/6 mice exposed to a single oral dose of BDE 47 (0, 1, 10, or 30 mg /kg) on postnatal day (PND) 10. Behavioral endpoints assessing sensory and motor maturation were examined on PNDs 12, 14, 16, 18, 32, and 88. Motor activity was also examined at 2 and 4 months in a separate group of mice. BDE 47 exposure (particularly the highest dose) significantly increased body weight on PND 47 and thereafter. There was altered ontogeny in a few measures of neuromotor development; however, other developmental milestones and sensory responses were not altered. Motor activity was altered at both 2 and 4 months, with BDE 47-treated mice (all dose groups) displaying pronounced hyperactivity at 4 months. These data indicate that acute exposure to BDE 47 during postnatal development may produce subtle changes in the development of neuromotor systems that may alter adult behavior. JF - Neurotoxicology and Teratology AU - Gee, J R AU - Moser, V C AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, United States, Moser.ginger@epa.gov Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 79 EP - 87 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 30 IS - 2 SN - 0892-0362, 0892-0362 KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - polybrominated diphenyl ethers KW - Perinatal exposure KW - Body weight KW - Cognitive ability KW - Motor activity KW - diphenyl ether KW - Ontogeny KW - Congeners KW - Fire retardant chemicals KW - Children KW - Hyperactivity KW - N3 11003:Developmental neuroscience KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20568144?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Acute+postnatal+exposure+to+brominated+diphenylether+47+delays+neuromotor+ontogeny+and+alters+motor+activity+in+mice&rft.au=Gee%2C+J+R%3BMoser%2C+V+C&rft.aulast=Gee&rft.aufirst=J&rft.date=2008-04-01&rft.volume=30&rft.issue=2&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2007.11.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - polybrominated diphenyl ethers; Body weight; Perinatal exposure; Cognitive ability; diphenyl ether; Motor activity; Congeners; Ontogeny; Fire retardant chemicals; Children; Hyperactivity DO - http://dx.doi.org/10.1016/j.ntt.2007.11.001 ER - TY - JOUR T1 - Environmental protection Agency's (Guyana) role in sea turtle conservation AN - 20421830; 9094418 AB - The decline of sea turtles in Guyana began during the 1960s, when predominantly female turtles were targets for hunters for their eggs and meat. Additionally, many turtles were entangled in fishing nets. These were the two main threats which led to concern for the protection of sea turtles in Guyana. The Guyana Marine Turtle Conservation Society (GMTCS) was the first Non-Governmental Organization established for the protection and conservation of marine turtles. Established in April 14, 2000, its vision includes promoting the establishment of a proposed protected area of approximately 90-mile stretch of beach along the north-west coast of Guyana, called Shell Beach and "managing this ecosystem to promote the conservation and sustainable utilization of the resources of the area for the benefit of all stakeholders." Shell Beach is the nesting ground for four of the world's eight species of marine turtles, namely: Leatherback (Dermochelys coriacea), Olive Ridley (Lepidochelys olivacea), Green (Chelonia mydas) and the Hawksbill (Eretmochelys imbricata). In addition, a Memorandum of Understanding was signed between the Environmental Protection Agency (EPA)-Guyana and GMTCS in August 2003. This collaboration provides for data collection by the GMTCS and joint analysis of this data by the EPA. The objectives of the data analysis are to compare the activities and the number of hatchlings produced by each species of turtle throughout the nesting season (March-August annually). The analysis focuses on the number of turtles observed; number of nests; number of false crawls; number of turtles returned and the number of unseen turtles. Of the data analyzed, the greatest number of green turtle nests was noted in April of 2005 where 46 nests were counted. Leatherbacks are the most commonly observed species, and nesting remained at high levels (eg. 275 nests were recorded for 2005). The number of hawksbills are smaller in representation for this year, 17 were observed as compared to 8 in the previous year. The Olive-Ridley is rarer, only two were observed in 2004, one nest recorded. The month of June is the peak of the season where the greatest numbers of turtles are encountered and the greatest number of nests are recorded as well. Over the five years (2001-2005), the greatest number of turtles was observed in 2005 and the greatest number of nests was seen in 2004. In terms of turtles hatched, the year 2004 had the highest number of turtle hatchlings (3066). However, this number declined to 1,714 in 2005. Of all the species, leatherbacks produced the greatest number of hatchlings over the 5 year period. No hatchlings were observed in 2002. It is our hope that with continued monitoring of the beach by the GMTCS, sea turtles will continue to nest at the beach. With constant research and monitoring, there should be a decline in poaching and slaughter of adult females. The EPA of Guyana and GMTCS will continue to work closely to analyze data from the nesting beaches and to share information for decision-making and management of marine turtles in Guyana and around the world. The EPA and GMTCS would like to express sincere gratitude to the organisations as well as to the Sea Turtle Symposium for your generous donations in order to make this day possible. JF - NOAA Technical Memorandum NMFS SEFSC AU - Saheed, DSA AD - Environmental Protection Agency (Guyana) - 263 Earl's Avenue Subryanville Georgetown Guyana A2 - Rees, Alan F A2 - Frick, Michael A2 - Panagopoulou, Aliki A2 - Williams, Kris Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 247 PB - National Marine Fisheries Service - SEFSC, Miami Laboratory - Sea Turtle Program 75 Virginia Beach Drive Miami FL 33149 USA IS - 569 KW - Green turtle KW - Hawksbill KW - Leatherback KW - Olive ridley KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - NMFS-SEFSC-569 KW - Marine KW - ASW, Guyana KW - Beaches KW - Fishing nets KW - Aquatic reptiles KW - Data collections KW - Eretmochelys imbricata KW - Coastal zone management KW - Lepidochelys olivacea KW - Shore protection KW - Interspecific relationships KW - Breeding sites KW - Chelonia mydas KW - Nesting KW - Nature conservation KW - Reproductive behaviour KW - Dermochelys coriacea KW - Q5 08523:Conservation, wildlife management and recreation KW - O 4090:Conservation and Environmental Protection KW - Q1 08423:Behaviour KW - Q2 09124:Coastal zone management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20421830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=NOAA+Technical+Memorandum+NMFS+SEFSC&rft.atitle=Environmental+protection+Agency%27s+%28Guyana%29+role+in+sea+turtle+conservation&rft.au=Saheed%2C+DSA&rft.aulast=Saheed&rft.aufirst=DSA&rft.date=2008-04-01&rft.volume=&rft.issue=569&rft.spage=247&rft.isbn=&rft.btitle=&rft.title=NOAA+Technical+Memorandum+NMFS+SEFSC&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-03-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Beaches; Shore protection; Fishing nets; Breeding sites; Interspecific relationships; Nesting; Aquatic reptiles; Nature conservation; Data collections; Reproductive behaviour; Coastal zone management; Lepidochelys olivacea; Chelonia mydas; Dermochelys coriacea; Eretmochelys imbricata; ASW, Guyana; Marine ER - TY - JOUR T1 - Development and test application of a screening-level mercury fate model and tool for evaluating wildlife exposure risk for surface waters with mercury-contaminated sediments (SERAFM) AN - 20205064; 7941178 AB - Complex chemical cycling of mercury in aquatic ecosystems means that tracing the linkage between anthropogenic and natural loadings of mercury to watersheds and water bodies and associated concentrations in the environment are difficult to establish without the assistance of numerical models that describe biogeochemical controls on mercury distribution and availability to organisms. This paper presents an overview of a process-based, steady-state model developed for state and water quality managers and scientists to assist in ecological risk assessments for mercury in aquatic environments. SERAFM (Spreadsheet-based Ecological Risk Assessment for the Fate of Mercury) incorporates the chemical, physical, and biological processes governing mercury transport and fate in a surface water including atmospheric deposition, watershed transport and transformation, solid transport and cycling within the water body, and water body mercury processes. This modelling framework was designed to assist risk assessors in evaluating wildlife risk at the screening-level for an aquatic ecosystem with mercury-contaminated sediments. An example application of the model that is used to inform a regional risk assessment is presented in this manuscript. In the example provided, hazard quotients for exposed wildlife and humans are calculated by the model for three scenarios: historical case of mercury-contaminated sediments, required clean-up levels to protect the most sensitive species, and background conditions. The spreadsheet structure of SERAFM permits dismantling and reassembling of specific sub-modules, while maintaining transparency to permit flexibility in use and application. JF - Environmental Modelling & Software AU - Knightes, C D AD - Office of Research and Development, National Exposure Research Laboratory, Ecosystems Research Division, 960 College Station Road, Athens, GA, USA, knightes.chris@epa.gov Y1 - 2008/04// PY - 2008 DA - April 2008 SP - 495 EP - 510 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 23 IS - 4 SN - 1364-8152, 1364-8152 KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts; Aqualine Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Biotechnology and Bioengineering Abstracts KW - Transformation KW - water quality KW - Ecosystems KW - Surface Water KW - Water quality KW - Watersheds KW - Toxicity tests KW - transparency KW - software KW - Numerical models KW - Biogeochemistry KW - Wildlife KW - Aquatic ecosystems KW - Aquatic environment KW - Model Studies KW - Pollutant deposition KW - Water management KW - Load Distribution KW - Mercury KW - Risk assessment KW - water bodies KW - Surface water KW - Risks KW - Models KW - Computer programs KW - Assessments KW - Sediment pollution KW - Mathematical models KW - Sediments KW - Risk KW - Reviews KW - aquatic ecosystems KW - Mercury transport KW - W 30950:Waste Treatment & Pollution Clean-up KW - M2 551.510.42:Air Pollution (551.510.42) KW - Q2 09264:Sediments and sedimentation KW - P 0000:AIR POLLUTION KW - SW 3030:Effects of pollution KW - AQ 00008:Effects of Pollution KW - Q5 08502:Methods and instruments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20205064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Modelling+%26+Software&rft.atitle=Development+and+test+application+of+a+screening-level+mercury+fate+model+and+tool+for+evaluating+wildlife+exposure+risk+for+surface+waters+with+mercury-contaminated+sediments+%28SERAFM%29&rft.au=Knightes%2C+C+D&rft.aulast=Knightes&rft.aufirst=C&rft.date=2008-04-01&rft.volume=23&rft.issue=4&rft.spage=495&rft.isbn=&rft.btitle=&rft.title=Environmental+Modelling+%26+Software&rft.issn=13648152&rft_id=info:doi/10.1016%2Fj.envsoft.2007.07.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Sediment pollution; Mathematical models; Surface water; Biogeochemistry; Water management; Mercury; Watersheds; Toxicity tests; Risks; Risk assessment; Transformation; Wildlife; Water quality; Aquatic ecosystems; Sediments; Aquatic environment; Models; Computer programs; software; Reviews; Numerical models; Ecosystems; Mercury transport; water quality; water bodies; transparency; Pollutant deposition; aquatic ecosystems; Risk; Assessments; Load Distribution; Surface Water; Model Studies DO - http://dx.doi.org/10.1016/j.envsoft.2007.07.002 ER - TY - JOUR T1 - A method for evaluating spatially-resolved NO sub(x) emissions using Kalman filter inversion, direct sensitivities, and space-based NO sub(2) observations AN - 20128947; 10078245 AB - An inverse modeling method was developed and tested for identifying possible biases in emission inventories using satellite observations. The relationships between emission inputs and modeled ambient concentrations were estimated using sensitivities calculated with the decoupled direct method in three dimensions (DDM-3D) implemented within the framework of the Community Multiscale Air Quality (CMAQ) regional model. As a case study to test the approach, the method was applied to regional ground-level NO sub(x) emissions in the southeastern United States as constrained by the Scanning Imaging Absorption Spectrometer for Atmospheric Chartography (SCIAMACHY) satellite derived observations of NO sub(2) column densities. A controlled QUOTATION_MARKpseudodataQUOTATION_MARK scenario with a known solution was used to establish that the methodology can achieve the correct solution, and the approach was then applied to a summer 2004 period where the satellite data are available. The results indicate that emissions biases differ in urban and rural areas of the southeast. The method suggested slight downward (less than 10%) adjustment to urban emissions, while rural region results were found to be highly sensitive to NO sub(x) processes in the upper troposphere. As such, the bias in the rural areas is likely not solely due to biases in the ground-level emissions. It was found that CMAQ was unable to predict the significant level of NO sub(2) in the upper troposphere that was observed during the NASA Intercontinental Chemical Transport Experiment (INTEX) measurement campaign. The reasons for the underestimation likely include combination of a lack of lightning emissions and a short modeled lifetime of NO sub(x) aloft. Therefore, the best correlation between satellite observations and modeled NO sub(2) column densities, as well as comparison to ground-level observations of NO sub(2), was obtained from performing the inverse while accounting for the significant presence of NO sub(2) in the upper troposphere not captured by the regional model. JF - Atmospheric Chemistry and Physics Discussions AU - Napelenok, S L AU - Pinder, R W AU - Gilliland, AB AU - Martin, R V AD - Atmospheric Sciences Modeling Division, Air Resources Laboratory, National Oceanic and Atmospheric Administration, in partnership with the United States Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, NC 27711, USA Y1 - 2008/04/01/ PY - 2008 DA - 2008 Apr 01 SP - 6469 EP - 6499 PB - European Geophysical Society, Max-Planck-Str. 13 Katlenburg-Lindau Germany VL - 8 IS - 2 SN - 1680-7367, 1680-7367 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - Emission inventories KW - Absorption KW - Emissions KW - Sensitivity KW - Atmospheric pollution KW - Chemical transport KW - Satellite instrumentation KW - Inversions KW - lightning KW - Inversion KW - Atmospheric chemistry KW - Lightning KW - Correlations KW - Remote sensing KW - Air quality KW - USA, Southeast KW - Emission measurements KW - Urban areas KW - Kalman filter KW - Troposphere KW - Satellites KW - case studies KW - Satellite data KW - Regional-scale models KW - summer KW - Rural areas KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20128947?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Chemistry+and+Physics+Discussions&rft.atitle=A+method+for+evaluating+spatially-resolved+NO+sub%28x%29+emissions+using+Kalman+filter+inversion%2C+direct+sensitivities%2C+and+space-based+NO+sub%282%29+observations&rft.au=Napelenok%2C+S+L%3BPinder%2C+R+W%3BGilliland%2C+AB%3BMartin%2C+R+V&rft.aulast=Napelenok&rft.aufirst=S&rft.date=2008-04-01&rft.volume=8&rft.issue=2&rft.spage=6469&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Chemistry+and+Physics+Discussions&rft.issn=16807367&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA, Southeast; Emissions; Satellites; Remote sensing; Troposphere; Air quality; Sensitivity; Rural areas; Chemical transport; Absorption; Inversion; summer; Emission measurements; Atmospheric chemistry; Emission inventories; case studies; lightning; Urban areas; Satellite data; Atmospheric pollution models; Regional-scale models; Atmospheric pollution; Lightning; Kalman filter; Satellite instrumentation; Inversions; Correlations ER - TY - JOUR T1 - A protocol for assessing applications to selectively clear vegetation in Australia AN - 20049922; 8809727 AB - Broadscale clearance of native vegetation has been outlawed in most Australian states but there may be provisions for selective thinning to redress increases in woody vegetation (vegetation thickening) under existing legislation. A procedure described here for Queensland, Australia allows selective thinning in most vegetation types where vegetation thickening is demonstrated by changes in woody cover determined from time- series aerial photography. Before selective thinning would be allowed, thickening has to be demonstrated by a greater than 30% woody cover increase relative to the cover on the earliest aerial photograph. Retention thresholds prohibit the clearing of all mature trees and require that immature trees are retained according to prescribed densities. These thresholds are developed from field data and are specific to broad structural types of vegetation. Thinning is precluded from some vegetation types and the structural types of vegetation defining retention densities can be identified throughout Queensland with the assistance of a Regional Ecosystem mapping coverage. The procedure is compared with an alternative prepared for New South Wales. The Queensland procedure only allows selective thinning where vegetation thickening can be demonstrated and it is argued that the retention thresholds are designed to maintain the ecological integrity of the native vegetation. By contrast, the procedure for New South Wales has the potential for widespread application and will substantially undermine biodiversity values given that it allows a radical change of land-use including cropping. The Queensland procedure is equitable for applicants, provides landholders with a tenable management option to redress vegetation thickening, but is sufficiently prescriptive to preserve the character of the natural vegetation. The procedure forms the basis of an operational policy in Queensland. JF - Land Use Policy AU - Fensham, R J AD - Queensland Herbarium, Environmental Protection Agency, Mt Coot-tha Road, Toowong, Queensland 4066, Australia, rod.fensham@epa.qld.gov.au Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 249 EP - 258 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 25 IS - 2 SN - 0264-8377, 0264-8377 KW - Ecology Abstracts; Sustainability Science Abstracts KW - thinning KW - Trees KW - Australia, Queensland KW - Biodiversity KW - Biological diversity KW - Aerial photography KW - Mapping KW - Data processing KW - woody plants KW - Vegetation KW - Thinning KW - natural vegetation KW - Australia, New South Wales KW - Natural vegetation KW - Legislation KW - Radicals KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20049922?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Land+Use+Policy&rft.atitle=A+protocol+for+assessing+applications+to+selectively+clear+vegetation+in+Australia&rft.au=Fensham%2C+R+J&rft.aulast=Fensham&rft.aufirst=R&rft.date=2008-04-01&rft.volume=25&rft.issue=2&rft.spage=249&rft.isbn=&rft.btitle=&rft.title=Land+Use+Policy&rft.issn=02648377&rft_id=info:doi/10.1016%2Fj.landusepol.2007.07.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Australia, Queensland; Australia, New South Wales; Vegetation; thinning; Trees; Aerial photography; Legislation; Biological diversity; Mapping; woody plants; natural vegetation; Thinning; Natural vegetation; Radicals; Data processing; Biodiversity DO - http://dx.doi.org/10.1016/j.landusepol.2007.07.001 ER - TY - JOUR T1 - Deciphering Naturally Occurring Pb Contamination Impacting Drinking Water Wells: Shaker Village Catchment, Maine AN - 19808667; 8681379 AB - Trace Pb concentrations in groundwater within glacial deposits across Maine fluctuate considerably. Deciphering the distribution and sources of naturally occurring Pb in groundwater with only the use of conventional anomaly identification techniques presents a challenge. In a representative catchment, a coupled Markov chain Monte Carlo (MCMC) model conditioned by 46 boreholes permits a visualization of a complex of ancient braided stream channels, possibly containing recurrent elevated groundwater Pb over 15 is a subset of g L- 1. Stable Pb isotopes are reported to aid the source definition of dispersed groundwater Pb in the outwash deposits. JF - Environmental Forensics AU - Sidle, W C AU - Allen, Derrick AD - United States Environmental Protection Agency, National Risk and Management Research Laboratory, Cincinnati, OH Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 197 EP - 204 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 9 IS - 2 SN - 1527-5922, 1527-5922 KW - Pollution Abstracts; Water Resources Abstracts KW - Monte Carlo simulation KW - Isotopes KW - Contamination KW - villages KW - Lead KW - Drinking Water KW - Permits KW - Catchment Areas KW - Outwash KW - Braided Streams KW - Channels KW - Markov Process KW - boreholes KW - Catchments KW - Water wells KW - USA, Maine KW - Groundwater KW - Drinking water KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19808667?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Forensics&rft.atitle=Deciphering+Naturally+Occurring+Pb+Contamination+Impacting+Drinking+Water+Wells%3A+Shaker+Village+Catchment%2C+Maine&rft.au=Sidle%2C+W+C%3BAllen%2C+Derrick&rft.aulast=Sidle&rft.aufirst=W&rft.date=2008-04-01&rft.volume=9&rft.issue=2&rft.spage=197&rft.isbn=&rft.btitle=&rft.title=Environmental+Forensics&rft.issn=15275922&rft_id=info:doi/10.1080%2F15275920802122072 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Monte Carlo simulation; Channels; Isotopes; boreholes; Contamination; Catchments; Water wells; villages; Drinking water; Groundwater; Lead; Markov Process; Drinking Water; Catchment Areas; Outwash; Braided Streams; Permits; USA, Maine DO - http://dx.doi.org/10.1080/15275920802122072 ER - TY - JOUR T1 - Increased Transcription of Immune and Metabolic Pathways in Naive and Allergic Mice Exposed to Diesel Exhaust AN - 19705936; 8090212 AB - Diesel exhaust (DE) has been shown to enhance allergic sensitization in animals following high-dose instillation or chronic inhalation exposure scenarios. The purpose of this study was to determine if short-term exposures to diluted DE enhance allergic immune responses to antigen, and identify possible mechanisms using microarray technology. BALB/c mice were exposed to filtered air or diluted DE to yield particle concentrations of 500 or 2000 mu g/m super(3) 4 h/day on days 0-4. Mice were immunized intranasally with ovalbumin (OVA) antigen or saline on days 0-2, challenged on day 18 with OVA or saline, and all mice were challenged with OVA on day 28. Mice were necropsied either 4 h after the last DE exposure on day 4, or 18, 48, and 96 h after the last challenge. Immunological endpoints included OVA-specific serum IgE, biochemical and cellular profiles of bronchoalveolar lavage (BAL), and cytokine production in the BAL. OVA-immunized mice exposed to both concentrations of DE had increased eosinophils, neutrophils, lymphocytes, and interleukin-6 (high dose only) post-challenge compared with OVA control, whereas DE/saline exposure yielded increases in neutrophils at the high dose only. Transcriptional microarray analysis 4 h after the last DE exposure demonstrated distinct gene expression profiles for the high-dose DE/OVA and DE/saline groups. DE/OVA induced oxidative stress and metabolism pathways, whereas DE in the absence of immunization modulated cell cycle control, growth and differentiation, G-proteins, and cell adhesion pathways. This study shows for the first time early changes in gene expression induced by the combination of DE inhalation and mucosal immunization, which resulted in stronger development of allergic eosinophilia. JF - Toxicological Sciences AU - Stevens, Tina AU - Krantz, Quentin T AU - Linak, William P AU - Hester, Susan AU - Gilmour, MIan AD - Curriculum of Toxicology, University of North Carolina, Chapel Hill, North Carolina 27599. Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory. Air Pollution and Prevention Control Division, National Risk Management Research Laboratory. Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711 Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 359 EP - 370 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 102 IS - 2 SN - 1096-6080, 1096-6080 KW - Biochemistry Abstracts 2: Nucleic Acids; Toxicology Abstracts; Immunology Abstracts KW - Interleukin 6 KW - Inhalation KW - Ovalbumin KW - Mucosa KW - Cell cycle KW - Lymphocytes KW - Leukocytes (eosinophilic) KW - DNA microarrays KW - Oxidative metabolism KW - Gene expression KW - Differentiation KW - Hypersensitivity KW - Bronchus KW - Oxidative stress KW - Metabolic pathways KW - Leukocytes (neutrophilic) KW - Transcription KW - Guanine nucleotide-binding protein KW - Eosinophilia KW - Alveoli KW - Immunization KW - Cell adhesion KW - Exhausts KW - Immunoglobulin E KW - Diesel KW - F 06955:Immunomodulation & Immunopharmacology KW - N 14810:Methods KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19705936?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Increased+Transcription+of+Immune+and+Metabolic+Pathways+in+Naive+and+Allergic+Mice+Exposed+to+Diesel+Exhaust&rft.au=Stevens%2C+Tina%3BKrantz%2C+Quentin+T%3BLinak%2C+William+P%3BHester%2C+Susan%3BGilmour%2C+MIan&rft.aulast=Stevens&rft.aufirst=Tina&rft.date=2008-04-01&rft.volume=102&rft.issue=2&rft.spage=359&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Inhalation; Interleukin 6; Ovalbumin; Cell cycle; Mucosa; Leukocytes (eosinophilic); Lymphocytes; DNA microarrays; Oxidative metabolism; Gene expression; Differentiation; Hypersensitivity; Bronchus; Oxidative stress; Metabolic pathways; Leukocytes (neutrophilic); Guanine nucleotide-binding protein; Transcription; Eosinophilia; Immunization; Alveoli; Exhausts; Cell adhesion; Immunoglobulin E; Diesel ER - TY - JOUR T1 - Lack of Alterations in Thyroid Hormones Following Exposure to Polybrominated Diphenyl Ether 47 during a Period of Rapid Brain Development in Mice AN - 19611961; 8590543 AB - Thyroid alterations have been shown to occur following exposure to polybrominated diphenyl ether (PBDE) mixtures, possibly indicating that disruptions in thyroid hormone levels may underlie behavior deficits observed in animals following postnatal PBDE exposure. This study determined whether acute postnatal exposure to PBDE-47 would alter thyroid hormones. Mice were dosed with PBDE-47 on postnatal day 10, and serum collected either 1, 5, or 10 days after the dose. No effect was observed on thyroxine and triiodothyronine levels at any age examined. This suggests that the neurological abnormalities reported in mice exposed to PBDE-47 are not due to acute changes in circulating thyroid hormones at these observed periods. JF - Drug and Chemical Toxicology AU - Gee, Jillian R AU - Hedge, Joan M AU - Moser, Virginia C AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina, USA Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 245 EP - 254 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 31 IS - 2 SN - 0148-0545, 0148-0545 KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Thyroid hormones KW - polybrominated diphenyl ethers KW - Age KW - Thyroxine KW - Brain KW - Triiodothyronine KW - X 24310:Pharmaceuticals KW - N3 11003:Developmental neuroscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19611961?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Drug+and+Chemical+Toxicology&rft.atitle=Lack+of+Alterations+in+Thyroid+Hormones+Following+Exposure+to+Polybrominated+Diphenyl+Ether+47+during+a+Period+of+Rapid+Brain+Development+in+Mice&rft.au=Gee%2C+Jillian+R%3BHedge%2C+Joan+M%3BMoser%2C+Virginia+C&rft.aulast=Gee&rft.aufirst=Jillian&rft.date=2008-04-01&rft.volume=31&rft.issue=2&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=Drug+and+Chemical+Toxicology&rft.issn=01480545&rft_id=info:doi/10.1080%2F01480540701873194 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Thyroid hormones; Age; polybrominated diphenyl ethers; Brain; Thyroxine; Triiodothyronine DO - http://dx.doi.org/10.1080/01480540701873194 ER - TY - JOUR T1 - Common Loon Survival Rates and Mercury in New England and Wisconsin AN - 19554580; 8701396 AB - Bioaccumulation of toxic environmental mercury may affect the vital rates of piscivores such as the common loon (Gavia immer). Although immediate effects of mercury on early development or reproduction can be determined from short-term field studies or dosing experiments, long-term effects on survival for a long-lived species such as the common loon must be discerned from large, long-term observational data sets. We analyzed band-resight and mercury data for 776 adult loons in Wisconsin and New England, USA, from 1991 to 2001 to 1) estimate annual survival rates and 2) investigate the relation between mercury exposure and survival. The model-averaged estimate of apparent survival was 0.87, whereas the approximate survival rate (accounting for movement) was 0.92. We found no differences in apparent survival by geographic location or sex and no relation between survival and mercury. Power analyses showed that we were only likely to detect differences in survival .3%. Small differences in survival (<3%), which may be important to loon population viability, were unlikely to be detected in our dataset. JF - Journal of Wildlife Management AU - Mitro, Matthew G AU - Evers, David C AU - Meyer, Michael W AU - Piper, Walter H AD - United States Environmental Protection Agency, Atlantic Ecology Division, 27 Tarzwell Drive, Narragansett, RI 02882, USA Y1 - 2008/04// PY - 2008 DA - Apr 2008 SP - 665 EP - 673 PB - Wildlife Society, 5410 Grosvenor Lane VL - 72 IS - 3 SN - 0022-541X, 0022-541X KW - Pollution Abstracts; Ecology Abstracts KW - common loon KW - Gavia immer KW - mercury effects KW - New England KW - populations KW - survival KW - Wisconsin KW - Wildlife management KW - Data processing KW - Survival KW - USA, Wisconsin KW - Long-term effects KW - Bioaccumulation KW - USA, New England KW - Mercury KW - Reproduction KW - P 6000:TOXICOLOGY AND HEALTH KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19554580?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Management&rft.atitle=Common+Loon+Survival+Rates+and+Mercury+in+New+England+and+Wisconsin&rft.au=Mitro%2C+Matthew+G%3BEvers%2C+David+C%3BMeyer%2C+Michael+W%3BPiper%2C+Walter+H&rft.aulast=Mitro&rft.aufirst=Matthew&rft.date=2008-04-01&rft.volume=72&rft.issue=3&rft.spage=665&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Management&rft.issn=0022541X&rft_id=info:doi/10.2193%2F2006-551 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Long-term effects; Wildlife management; Bioaccumulation; Data processing; Mercury; Survival; Reproduction; survival; Gavia immer; USA, New England; USA, Wisconsin DO - http://dx.doi.org/10.2193/2006-551 ER - TY - CPAPER T1 - National Environmental Information Exchange Network T2 - 2008 Ground Water Summit (#5095) AN - 40799389; 4795898 JF - 5095) AU - Sterling, Doreen Y1 - 2008/03/30/ PY - 2008 DA - 2008 Mar 30 KW - Environmental information KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40799389?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=5095%29&rft.atitle=National+Environmental+Information+Exchange+Network&rft.au=Sterling%2C+Doreen&rft.aulast=Sterling&rft.aufirst=Doreen&rft.date=2008-03-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=5095%29&rft.issn=&rft_id=info:doi/ L2 - http://ngwa.confex.com/ngwa/2008gws/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Using Watershed Management to Implement Total Maximum Daily Loads T2 - 2008 Conference on 21st Century Watershed Technology: Improving Water Quality (ASABE 2008) AN - 40826725; 4804898 JF - 2008 Conference on 21st Century Watershed Technology: Improving Water Quality (ASABE 2008) AU - Brasier, Francoise M Y1 - 2008/03/29/ PY - 2008 DA - 2008 Mar 29 KW - Watersheds KW - River basin management KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40826725?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Conference+on+21st+Century+Watershed+Technology%3A+Improving+Water+Quality+%28ASABE+2008%29&rft.atitle=Using+Watershed+Management+to+Implement+Total+Maximum+Daily+Loads&rft.au=Brasier%2C+Francoise+M&rft.aulast=Brasier&rft.aufirst=Francoise&rft.date=2008-03-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Conference+on+21st+Century+Watershed+Technology%3A+Improving+Water+Quality+%28ASABE+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asabe.org/meetings/water2008/technicalprogram.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - National Hydrography Dataset Plus (NHDPlus). T2 - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AN - 40828884; 4804894 JF - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AU - Wortman, Santina AU - Dewald, Tommy Y1 - 2008/03/17/ PY - 2008 DA - 2008 Mar 17 KW - Hydrography KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40828884?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.atitle=National+Hydrography+Dataset+Plus+%28NHDPlus%29.&rft.au=Wortman%2C+Santina%3BDewald%2C+Tommy&rft.aulast=Wortman&rft.aufirst=Santina&rft.date=2008-03-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/San_Mateo2008/index.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Spatial Trends in Surface Water Chemistry: Implications for the Biotic Ligand Model. T2 - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AN - 40827441; 4804746 JF - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AU - Carleton, James Y1 - 2008/03/17/ PY - 2008 DA - 2008 Mar 17 KW - Surface water KW - Models KW - Ligands KW - Surface chemistry KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40827441?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.atitle=Spatial+Trends+in+Surface+Water+Chemistry%3A+Implications+for+the+Biotic+Ligand+Model.&rft.au=Carleton%2C+James&rft.aulast=Carleton&rft.aufirst=James&rft.date=2008-03-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/San_Mateo2008/index.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - National Hydrography Dataset Plus (NHDPlus) Applications Sampler. T2 - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AN - 40826429; 4804791 JF - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AU - Dewald, Tommy Y1 - 2008/03/17/ PY - 2008 DA - 2008 Mar 17 KW - Hydrography KW - Samplers KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40826429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.atitle=National+Hydrography+Dataset+Plus+%28NHDPlus%29+Applications+Sampler.&rft.au=Dewald%2C+Tommy&rft.aulast=Dewald&rft.aufirst=Tommy&rft.date=2008-03-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/San_Mateo2008/index.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - BASINS 4.0 (Open Source GIS): Better Assessment Science Integrating Point and Non-point Sources. T2 - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AN - 40823821; 4804879 JF - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AU - Carleton, James AU - Partington, Ed AU - Wellman, Marjorie AU - Wells, David AU - Kittle, Jack AU - Duda, Paul Y1 - 2008/03/17/ PY - 2008 DA - 2008 Mar 17 KW - Nonpoint pollution KW - Geographic information systems KW - Basins KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40823821?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.atitle=BASINS+4.0+%28Open+Source+GIS%29%3A+Better+Assessment+Science+Integrating+Point+and+Non-point+Sources.&rft.au=Carleton%2C+James%3BPartington%2C+Ed%3BWellman%2C+Marjorie%3BWells%2C+David%3BKittle%2C+Jack%3BDuda%2C+Paul&rft.aulast=Carleton&rft.aufirst=James&rft.date=2008-03-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/San_Mateo2008/index.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - e-Estuary: Developing a Decision-Support System for Coastal Management. T2 - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AN - 40822761; 4804841 JF - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AU - Detenbeck, Naomi AU - Pelletier, M C AU - Abdelrhman, M AU - Rego, S AU - Nixon, M Y1 - 2008/03/17/ PY - 2008 DA - 2008 Mar 17 KW - Decision support systems KW - Coastal zone management KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40822761?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.atitle=e-Estuary%3A+Developing+a+Decision-Support+System+for+Coastal+Management.&rft.au=Detenbeck%2C+Naomi%3BPelletier%2C+M+C%3BAbdelrhman%2C+M%3BRego%2C+S%3BNixon%2C+M&rft.aulast=Detenbeck&rft.aufirst=Naomi&rft.date=2008-03-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/San_Mateo2008/index.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Landscape Metrics Rendered by Hydrological Proximity to Sites on the Mississippi, Missouri, and Ohio Rivers. T2 - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AN - 40818592; 4804711 JF - Fifth American Water Resources Association Spring Specialty Conference on GIS and Water Resources AU - Nawrocki, Tatiana AU - Starry, Matthew AU - Moffett, Mary AU - Bolgrien, David Y1 - 2008/03/17/ PY - 2008 DA - 2008 Mar 17 KW - USA, Missouri KW - USA, Kentucky, Ohio R. KW - USA, Mississippi KW - River discharge KW - Landscape KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40818592?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.atitle=Landscape+Metrics+Rendered+by+Hydrological+Proximity+to+Sites+on+the+Mississippi%2C+Missouri%2C+and+Ohio+Rivers.&rft.au=Nawrocki%2C+Tatiana%3BStarry%2C+Matthew%3BMoffett%2C+Mary%3BBolgrien%2C+David&rft.aulast=Nawrocki&rft.aufirst=Tatiana&rft.date=2008-03-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Fifth+American+Water+Resources+Association+Spring+Specialty+Conference+on+GIS+and+Water+Resources&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/San_Mateo2008/index.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Developmental Toxicity Of Perfluorooctane Sulfonate (PFOS) is Not Dependent on Expression of Peroxisome Proliferator-Activated Receptor-Alpha (PPARa) in the Mouse. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40861469; 4813274 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Abbott, B D AU - Wolf, C J AU - Das, K P AU - Lau, C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Sulfonates KW - Peroxisome proliferator-activated receptors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40861469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Developmental+Toxicity+Of+Perfluorooctane+Sulfonate+%28PFOS%29+is+Not+Dependent+on+Expression+of+Peroxisome+Proliferator-Activated+Receptor-Alpha+%28PPARa%29+in+the+Mouse.&rft.au=Abbott%2C+B+D%3BWolf%2C+C+J%3BDas%2C+K+P%3BLau%2C+C&rft.aulast=Abbott&rft.aufirst=B&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Vinclozolin (V) Induces Reproductive Malformations and Infertility When Administered during Sexual but Not Gonadal Differentiation. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40861398; 4813260 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Gray, L E AU - Furr, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Infertility KW - Differentiation KW - Vinclozolin KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40861398?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Vinclozolin+%28V%29+Induces+Reproductive+Malformations+and+Infertility+When+Administered+during+Sexual+but+Not+Gonadal+Differentiation.&rft.au=Gray%2C+L+E%3BFurr%2C+J&rft.aulast=Gray&rft.aufirst=L&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Uncertainty Analysis of Human Extrapolations by Use of a PBPK Model for 1,2-Dichloroethane (DCE). T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40861267; 4813225 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Schlosser, P M AU - Barton, H A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40861267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Uncertainty+Analysis+of+Human+Extrapolations+by+Use+of+a+PBPK+Model+for+1%2C2-Dichloroethane+%28DCE%29.&rft.au=Schlosser%2C+P+M%3BBarton%2C+H+A&rft.aulast=Schlosser&rft.aufirst=P&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Integration of Toxicogenomics Data into Mode of Action Analyses for Cancer Risk Assessment. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40861130; 4813239 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Keshava, C AU - Keshava, N AU - Flowers, L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Cancer KW - Risk assessment KW - Integration KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40861130?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Integration+of+Toxicogenomics+Data+into+Mode+of+Action+Analyses+for+Cancer+Risk+Assessment.&rft.au=Keshava%2C+C%3BKeshava%2C+N%3BFlowers%2C+L&rft.aulast=Keshava&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Transcriptional Responses in Thyroid Tissues from Rats Treated with a Tumorigenic and a Non-tumorigenic Triazole Conazole Fungicide. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40860834; 4813220 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Hester, S AU - Nesnow, S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Fungicides KW - Thyroid KW - Rats KW - Triazoles KW - Transcription KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40860834?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Transcriptional+Responses+in+Thyroid+Tissues+from+Rats+Treated+with+a+Tumorigenic+and+a+Non-tumorigenic+Triazole+Conazole+Fungicide.&rft.au=Hester%2C+S%3BNesnow%2C+S&rft.aulast=Hester&rft.aufirst=S&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Adverse Heath Outcomes in Adult Offspring of Rats Undernourished in Utero Strain Comparison for Use in Developmental Origins of Health and Disease (DOHaD) Toxicity Studies. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40859611; 4813281 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Ellis-Hutchings, R AU - Grey, B AU - Norwood, J AU - Judy, R AU - Lau, C AU - Rogers, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Offspring KW - Heaths KW - Rats KW - Progeny KW - Strains KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40859611?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Adverse+Heath+Outcomes+in+Adult+Offspring+of+Rats+Undernourished+in+Utero+Strain+Comparison+for+Use+in+Developmental+Origins+of+Health+and+Disease+%28DOHaD%29+Toxicity+Studies.&rft.au=Ellis-Hutchings%2C+R%3BGrey%2C+B%3BNorwood%2C+J%3BJudy%2C+R%3BLau%2C+C%3BRogers%2C+J&rft.aulast=Ellis-Hutchings&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mode of Action Frameworks for Risk Assessment: Challenges and Opportunities for Progress. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40859563; 4813237 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Guyton, K Z AU - Barone, S AU - Brown, R C AU - Euling, S Y AU - Jinot, J AU - Makris, S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40859563?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Mode+of+Action+Frameworks+for+Risk+Assessment%3A+Challenges+and+Opportunities+for+Progress.&rft.au=Guyton%2C+K+Z%3BBarone%2C+S%3BBrown%2C+R+C%3BEuling%2C+S+Y%3BJinot%2C+J%3BMakris%2C+S&rft.aulast=Guyton&rft.aufirst=K&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mutagenic Mode of Action for Carcinogenicity: Comments on EPAs Draft Framework. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40859249; 4813238 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Hofmann, E L AU - Schoeny, R S AU - Putzrath, R M AU - Chu, M M AU - Cimino, M C AU - Dearfield, K L AU - Kligerman, A AU - Keshava, C AU - Keshava, N AU - McCarroll, N AU - Owen, R D Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - EPA KW - Carcinogenicity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40859249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Mutagenic+Mode+of+Action+for+Carcinogenicity%3A+Comments+on+EPAs+Draft+Framework.&rft.au=Hofmann%2C+E+L%3BSchoeny%2C+R+S%3BPutzrath%2C+R+M%3BChu%2C+M+M%3BCimino%2C+M+C%3BDearfield%2C+K+L%3BKligerman%2C+A%3BKeshava%2C+C%3BKeshava%2C+N%3BMcCarroll%2C+N%3BOwen%2C+R+D&rft.aulast=Hofmann&rft.aufirst=E&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Polycyclic Aromatic Hydrocarbon (PAH) Mixtures: Assessment of Cancer Risk Using a Proposed Relative Potency Factor (RPF) Approach. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40859204; 4813236 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Flowers, L AU - Carlson-Lynch, H AU - Gehlhaus, M AU - Hogan, K AU - Keshava, C AU - McClure, P AU - Rice, G AU - Stickney, J AU - Strong, J AU - Teuschler, L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Cancer KW - Polycyclic aromatic hydrocarbons KW - Risk assessment KW - Aromatic hydrocarbons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40859204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Polycyclic+Aromatic+Hydrocarbon+%28PAH%29+Mixtures%3A+Assessment+of+Cancer+Risk+Using+a+Proposed+Relative+Potency+Factor+%28RPF%29+Approach.&rft.au=Flowers%2C+L%3BCarlson-Lynch%2C+H%3BGehlhaus%2C+M%3BHogan%2C+K%3BKeshava%2C+C%3BMcClure%2C+P%3BRice%2C+G%3BStickney%2C+J%3BStrong%2C+J%3BTeuschler%2C+L&rft.aulast=Flowers&rft.aufirst=L&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Data-Derived Uncertainty Factor Approach in the Revised N-Methyl Carbamate Cumulative Risk Assessment. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40857207; 4813235 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Lowit, A AU - Reaves, M E AU - Setzer, R W AU - Moser, V C AU - Miller, D J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40857207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Data-Derived+Uncertainty+Factor+Approach+in+the+Revised+N-Methyl+Carbamate+Cumulative+Risk+Assessment.&rft.au=Lowit%2C+A%3BReaves%2C+M+E%3BSetzer%2C+R+W%3BMoser%2C+V+C%3BMiller%2C+D+J&rft.aulast=Lowit&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Fetal Testosterone Levels are Differentially Affected in Male Sprague Dawley and Wistar Rats after in Utero Exposure to Diethylhexyl Phthalate: A Dose Response Study. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40856678; 4813257 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Wilson, V S AU - Howdeshell, K L AU - Lambright, C S AU - Furr, J AU - Gray, L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Phthalates KW - Prenatal experience KW - Rats KW - Testosterone KW - Intrauterine exposure KW - Fetuses KW - Sex hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40856678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Fetal+Testosterone+Levels+are+Differentially+Affected+in+Male+Sprague+Dawley+and+Wistar+Rats+after+in+Utero+Exposure+to+Diethylhexyl+Phthalate%3A+A+Dose+Response+Study.&rft.au=Wilson%2C+V+S%3BHowdeshell%2C+K+L%3BLambright%2C+C+S%3BFurr%2C+J%3BGray%2C+L&rft.aulast=Wilson&rft.aufirst=V&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparing Pharmacokinetic Models for Perfluorooctanoic Acid in Mice. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40856607; 4813223 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Barton, H A AU - Lou, I AU - Lau, C AU - Hanson, R G AU - Lindstrom, A B AU - Strynar, M J AU - Setzer, R W Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Mice KW - Pharmacokinetics KW - Perfluorooctanoic acid KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40856607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Comparing+Pharmacokinetic+Models+for+Perfluorooctanoic+Acid+in+Mice.&rft.au=Barton%2C+H+A%3BLou%2C+I%3BLau%2C+C%3BHanson%2C+R+G%3BLindstrom%2C+A+B%3BStrynar%2C+M+J%3BSetzer%2C+R+W&rft.aulast=Barton&rft.aufirst=H&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Creation and Implementation of Data Resources Supporting Integrated Science Assessments of Criteria Air Pollutants T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40856466; 4813080 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Woodall, G M AU - Lorang, E AU - Luben, T AU - Wichers, L B AU - Ross, M AU - White, L D AU - Hassett-Sipple, B AU - Walsh, D Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Air pollution KW - Pollutants KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40856466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Creation+and+Implementation+of+Data+Resources+Supporting+Integrated+Science+Assessments+of+Criteria+Air+Pollutants&rft.au=Woodall%2C+G+M%3BLorang%2C+E%3BLuben%2C+T%3BWichers%2C+L+B%3BRoss%2C+M%3BWhite%2C+L+D%3BHassett-Sipple%2C+B%3BWalsh%2C+D&rft.aulast=Woodall&rft.aufirst=G&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of Normal Human Colon Cell Cultures to Identify Unregulated Disinfection By-Products (DBPs) with Carcinogenic Potential. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40846639; 4811920 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Jones, C AU - Thai, S AU - Ward, W AU - Moyer, M AU - DeAngelo, A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Disinfection KW - Byproducts KW - Carcinogenicity KW - Cell culture KW - Colon KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40846639?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Development+of+Normal+Human+Colon+Cell+Cultures+to+Identify+Unregulated+Disinfection+By-Products+%28DBPs%29+with+Carcinogenic+Potential.&rft.au=Jones%2C+C%3BThai%2C+S%3BWard%2C+W%3BMoyer%2C+M%3BDeAngelo%2C+A&rft.aulast=Jones&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dose-dependent Distribution and Elimination of Cis- and Trans-permethrin in the Rat T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40844950; 4811865 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Scollon, E J AU - Starr, J M AU - Hughes, M F AU - Tornero-Velez, R AU - Wheeler, H M AU - Ross, D G AU - DeVito, M J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Pharmacokinetics KW - Disposition KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40844950?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Dose-dependent+Distribution+and+Elimination+of+Cis-+and+Trans-permethrin+in+the+Rat&rft.au=Scollon%2C+E+J%3BStarr%2C+J+M%3BHughes%2C+M+F%3BTornero-Velez%2C+R%3BWheeler%2C+H+M%3BRoss%2C+D+G%3BDeVito%2C+M+J&rft.aulast=Scollon&rft.aufirst=E&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cardiovascular and Other Health Effects Associated with Arsenic Exposure in Inner Mongolia, China T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40844803; 4811770 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Mumford, J L AU - Xia, Y AU - Mo, J. AU - Wade, T AU - Li, Y. AU - Wu, K. AU - Sanders, W Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - China, People's Rep. KW - China, People's Rep., Inner Mongolia KW - Arsenic KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40844803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Cardiovascular+and+Other+Health+Effects+Associated+with+Arsenic+Exposure+in+Inner+Mongolia%2C+China&rft.au=Mumford%2C+J+L%3BXia%2C+Y%3BMo%2C+J.%3BWade%2C+T%3BLi%2C+Y.%3BWu%2C+K.%3BSanders%2C+W&rft.aulast=Mumford&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Curious History of Antimony and its Relevance to Human Risk Assessment. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40844635; 4811768 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Jowa, L AU - Howd, R Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Risk assessment KW - Historical account KW - Antimony KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40844635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=The+Curious+History+of+Antimony+and+its+Relevance+to+Human+Risk+Assessment.&rft.au=Jowa%2C+L%3BHowd%2C+R&rft.aulast=Jowa&rft.aufirst=L&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tissue Distribution and Urinary Excretion of Inorganic Arsenic and its Methylated Metabolites in C57BL/6 Mice Following Subchronic Exposure to Arsenate (ASV) in Drinking Water T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40844532; 4811759 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Kenyon, E M AU - Hughes, M F AU - Adair, B AU - Highfill, J AU - Crecelius, E A AU - Clewell, H J AU - Yager, J W Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Excretion KW - Metabolites KW - Mice KW - Drinking water KW - Arsenates KW - Arsenic KW - Urine KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40844532?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Tissue+Distribution+and+Urinary+Excretion+of+Inorganic+Arsenic+and+its+Methylated+Metabolites+in+C57BL%2F6+Mice+Following+Subchronic+Exposure+to+Arsenate+%28ASV%29+in+Drinking+Water&rft.au=Kenyon%2C+E+M%3BHughes%2C+M+F%3BAdair%2C+B%3BHighfill%2C+J%3BCrecelius%2C+E+A%3BClewell%2C+H+J%3BYager%2C+J+W&rft.aulast=Kenyon&rft.aufirst=E&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In Vivo Dermal Absorption of Pyrethroids in the Rat T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40844178; 4811867 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Hughes, M F AU - Edwards, B C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Pyrethroids KW - Absorption KW - Skin KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40844178?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=In+Vivo+Dermal+Absorption+of+Pyrethroids+in+the+Rat&rft.au=Hughes%2C+M+F%3BEdwards%2C+B+C&rft.aulast=Hughes&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of Risk Characterizations under the U.S. High Production Volume (HPV) Challenge Program. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40843372; 4812459 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Szilagyi, M AU - Seed, J AU - Henry, T AU - Scarano, L AU - Nguyen, N AU - Locke, D AU - Fehrenbacher, C AU - Townsend, M AU - Hernandez, O Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - USA KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40843372?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Development+of+Risk+Characterizations+under+the+U.S.+High+Production+Volume+%28HPV%29+Challenge+Program.&rft.au=Szilagyi%2C+M%3BSeed%2C+J%3BHenry%2C+T%3BScarano%2C+L%3BNguyen%2C+N%3BLocke%2C+D%3BFehrenbacher%2C+C%3BTownsend%2C+M%3BHernandez%2C+O&rft.aulast=Szilagyi&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of an Amphibian Life Cycle Assay for Endocrine Disruptor Testing. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40843056; 4812741 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Olmstead, A W AU - Korte, J AU - Holcombe, G AU - Kosian, P AU - Bennett, B AU - Woodis, K AU - Ostazeski, S AU - Lindberg-Livingston, A AU - Leland, I AU - Degitz, S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Life cycle KW - Endocrine disruptors KW - Amphibians KW - Endocrinology KW - Amphibiotic species KW - Developmental stages KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40843056?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Development+of+an+Amphibian+Life+Cycle+Assay+for+Endocrine+Disruptor+Testing.&rft.au=Olmstead%2C+A+W%3BKorte%2C+J%3BHolcombe%2C+G%3BKosian%2C+P%3BBennett%2C+B%3BWoodis%2C+K%3BOstazeski%2C+S%3BLindberg-Livingston%2C+A%3BLeland%2C+I%3BDegitz%2C+S&rft.aulast=Olmstead&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Atrazine (ATR), Deisopropylatrazine (DIA), and Diaminochlorotriazine (DACT) on the Hypothalamic-Pituitary-Adrenal (HPA) Axis in Female Rats. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40843005; 4812733 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Fraites, M P AU - Laws, S C AU - Ferrell, J AU - Buckalew, A AU - Cooper, R Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Atrazine KW - Herbicides KW - Rats KW - Hypothalamic-pituitary-adrenal axis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40843005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Effects+of+Atrazine+%28ATR%29%2C+Deisopropylatrazine+%28DIA%29%2C+and+Diaminochlorotriazine+%28DACT%29+on+the+Hypothalamic-Pituitary-Adrenal+%28HPA%29+Axis+in+Female+Rats.&rft.au=Fraites%2C+M+P%3BLaws%2C+S+C%3BFerrell%2C+J%3BBuckalew%2C+A%3BCooper%2C+R&rft.aulast=Fraites&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Consequences of Prenatal PFOA Exposure on Mouse Mammary Gland Growth and Development in F1 and F2 Offspring. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842954; 4812699 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - White, S S AU - Hines, E P AU - Stanko, J P AU - Fenton, S E Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Offspring KW - Prenatal experience KW - Progeny KW - Mammary gland KW - Glands KW - Growth KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Consequences+of+Prenatal+PFOA+Exposure+on+Mouse+Mammary+Gland+Growth+and+Development+in+F1+and+F2+Offspring.&rft.au=White%2C+S+S%3BHines%2C+E+P%3BStanko%2C+J+P%3BFenton%2C+S+E&rft.aulast=White&rft.aufirst=S&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Subchronic Episodic Exposure of Rats to Diesel Plus Ozone Induces Minimal Cardiopulmonary Effects. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842633; 4812020 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Schladweiler, M C AU - Ledbetter, A D AU - Shannahan, J AU - Wallenborn, J AU - Nyska, A AU - Malarkey, D AU - Richards, J AU - Tong, H AU - Devlin, R B AU - Kodavanti, U P Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Ozone KW - Rats KW - Diesel KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842633?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Subchronic+Episodic+Exposure+of+Rats+to+Diesel+Plus+Ozone+Induces+Minimal+Cardiopulmonary+Effects.&rft.au=Schladweiler%2C+M+C%3BLedbetter%2C+A+D%3BShannahan%2C+J%3BWallenborn%2C+J%3BNyska%2C+A%3BMalarkey%2C+D%3BRichards%2C+J%3BTong%2C+H%3BDevlin%2C+R+B%3BKodavanti%2C+U+P&rft.aulast=Schladweiler&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Selenium - Development of a Health Protective Concentration in Drinking Water. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842342; 4812475 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Fan, A M AU - Wang, Y AU - Howd, R A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Selenium KW - Drinking water KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842342?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Selenium+-+Development+of+a+Health+Protective+Concentration+in+Drinking+Water.&rft.au=Fan%2C+A+M%3BWang%2C+Y%3BHowd%2C+R+A&rft.aulast=Fan&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Review of the Role of Peroxisome Proliferators as Mediatiors of Environmental Toxicants during Development. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842301; 4812471 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Iyer, P AU - Donald, J M AU - Zeise, L AU - Golub, M S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Reviews KW - Toxicants KW - Peroxisomes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842301?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=A+Review+of+the+Role+of+Peroxisome+Proliferators+as+Mediatiors+of+Environmental+Toxicants+during+Development.&rft.au=Iyer%2C+P%3BDonald%2C+J+M%3BZeise%2C+L%3BGolub%2C+M+S&rft.aulast=Iyer&rft.aufirst=P&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Screening-Level Hazard Characterization of High Production Volume Chemicals. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842282; 4812458 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Sonawane, M AU - Henry, T AU - Townsend, M AU - Hernandez, O Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Chemicals KW - Hazards KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Screening-Level+Hazard+Characterization+of+High+Production+Volume+Chemicals.&rft.au=Sonawane%2C+M%3BHenry%2C+T%3BTownsend%2C+M%3BHernandez%2C+O&rft.aulast=Sonawane&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Current Challenges for Carcinogen Risk Assessment. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842249; 4812448 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Hammerstrom, K AU - Flowers, L AU - Hogan, K AU - Keshava, C AU - Sams, R AU - Wong, D AU - Kadry, A M AU - Vandenberg, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Risk assessment KW - Carcinogens KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Current+Challenges+for+Carcinogen+Risk+Assessment.&rft.au=Hammerstrom%2C+K%3BFlowers%2C+L%3BHogan%2C+K%3BKeshava%2C+C%3BSams%2C+R%3BWong%2C+D%3BKadry%2C+A+M%3BVandenberg%2C+J&rft.aulast=Hammerstrom&rft.aufirst=K&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Human Health Risk Assessment for Exposure to Polychlorinated Biphenyls in Contaminated Buildings. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842177; 4812477 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Wong-Yim, P AU - Wade, M AU - Davis, B AU - DiBasio, K AU - Taras, T Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Risk assessment KW - Buildings KW - PCB KW - Polychlorinated biphenyls KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842177?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Human+Health+Risk+Assessment+for+Exposure+to+Polychlorinated+Biphenyls+in+Contaminated+Buildings.&rft.au=Wong-Yim%2C+P%3BWade%2C+M%3BDavis%2C+B%3BDiBasio%2C+K%3BTaras%2C+T&rft.aulast=Wong-Yim&rft.aufirst=P&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An Approach for Toluene Chronic and 8-Hour Reference Exposure Levels with Benchmark Dose Analysis for Color Vision Impairment and Pbpk Models for Adult-Child Variability. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842153; 4812473 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Wang, A A AU - Dodge, D AU - Blaisdell, R Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Vision KW - Toluene KW - Benchmarks KW - Color vision KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842153?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=An+Approach+for+Toluene+Chronic+and+8-Hour+Reference+Exposure+Levels+with+Benchmark+Dose+Analysis+for+Color+Vision+Impairment+and+Pbpk+Models+for+Adult-Child+Variability.&rft.au=Wang%2C+A+A%3BDodge%2C+D%3BBlaisdell%2C+R&rft.aulast=Wang&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Vapor Intrusion to Indoor Air at a Site with Polycyclic Aromatic Hydrocarbons in Shallow Soil. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842099; 4812550 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Taras, T AU - LaPierre, A AU - Wade, M AU - Wong-Yim, P AU - Davis, B AU - Dalrymple, M AU - Polisini, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Soil KW - Polycyclic aromatic hydrocarbons KW - Vapors KW - Aromatic hydrocarbons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Vapor+Intrusion+to+Indoor+Air+at+a+Site+with+Polycyclic+Aromatic+Hydrocarbons+in+Shallow+Soil.&rft.au=Taras%2C+T%3BLaPierre%2C+A%3BWade%2C+M%3BWong-Yim%2C+P%3BDavis%2C+B%3BDalrymple%2C+M%3BPolisini%2C+J&rft.aulast=Taras&rft.aufirst=T&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dose-Response Comparisons of Single vs. Repeated Exposures in Developmental Toxicity Studies. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842047; 4812500 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Davis, J A AU - Gift, J S AU - Woodall, G M AU - Narotsky, M AU - Foureman, G L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Dose-response effects KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842047?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Dose-Response+Comparisons+of+Single+vs.+Repeated+Exposures+in+Developmental+Toxicity+Studies.&rft.au=Davis%2C+J+A%3BGift%2C+J+S%3BWoodall%2C+G+M%3BNarotsky%2C+M%3BFoureman%2C+G+L&rft.aulast=Davis&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Power to Detect a Difference: Determining Sample Size Requirements for Evaluation of Reproductive/Developmental Effects from Exposure to Complex Mixtures of Disinfection Byproducts. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40842036; 4812508 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Simmons, J AU - Dingus, C AU - Teuschler, L K AU - Rice, G E AU - Narotsky, M G Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Disinfection KW - Byproducts KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40842036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=The+Power+to+Detect+a+Difference%3A+Determining+Sample+Size+Requirements+for+Evaluation+of+Reproductive%2FDevelopmental+Effects+from+Exposure+to+Complex+Mixtures+of+Disinfection+Byproducts.&rft.au=Simmons%2C+J%3BDingus%2C+C%3BTeuschler%2C+L+K%3BRice%2C+G+E%3BNarotsky%2C+M+G&rft.aulast=Simmons&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Estimating Acceptable Levels of Exposure to Airborne Sensory Irritants using the RD50. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841889; 4812472 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Alexeeff, G V AU - Marty, M A AU - Salmon, A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Airborne sensing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841889?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Estimating+Acceptable+Levels+of+Exposure+to+Airborne+Sensory+Irritants+using+the+RD50.&rft.au=Alexeeff%2C+G+V%3BMarty%2C+M+A%3BSalmon%2C+A&rft.aulast=Alexeeff&rft.aufirst=G&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - U.S. EPA Integrated Risk Information System (IRIS) Reassessment of 1,1,2,2-Tetrachloroethane. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841834; 4812454 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Patton, G W AU - Berner, T Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - USA KW - Information systems KW - EPA KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841834?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=U.S.+EPA+Integrated+Risk+Information+System+%28IRIS%29+Reassessment+of+1%2C1%2C2%2C2-Tetrachloroethane.&rft.au=Patton%2C+G+W%3BBerner%2C+T&rft.aulast=Patton&rft.aufirst=G&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Rats, Monkeys, and Humans: Comparing Points of Departure for use in the Derivation of a Reference Concentration for 2-Hexanone. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841803; 4812452 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Persad, A S AU - Berner, T O AU - Stedeford, T Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Rats KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Rats%2C+Monkeys%2C+and+Humans%3A+Comparing+Points+of+Departure+for+use+in+the+Derivation+of+a+Reference+Concentration+for+2-Hexanone.&rft.au=Persad%2C+A+S%3BBerner%2C+T+O%3BStedeford%2C+T&rft.aulast=Persad&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of Physiological Parameters in Adult Rats and Mice for Populating an ACCESS Database. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841720; 4812421 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Sonawane, B R AU - Johns, D AU - Thompson, C AU - Barton, H AU - Hattis, D AU - Tardif, R AU - Krishnan, K Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Mice KW - Rats KW - Physiology KW - Databases KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Evaluation+of+Physiological+Parameters+in+Adult+Rats+and+Mice+for+Populating+an+ACCESS+Database.&rft.au=Sonawane%2C+B+R%3BJohns%2C+D%3BThompson%2C+C%3BBarton%2C+H%3BHattis%2C+D%3BTardif%2C+R%3BKrishnan%2C+K&rft.aulast=Sonawane&rft.aufirst=B&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Exploring Genetic Polymorphisms in Xenobiotic Metabolizing Enzymes that may Affect Response to Environmental Toxicants. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841470; 4812689 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Johns, D AU - Guyton, K Z AU - Sonawane, B AU - Ginsberg, G Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Xenobiotics KW - Toxicants KW - Enzymes KW - Gene polymorphism KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841470?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Exploring+Genetic+Polymorphisms+in+Xenobiotic+Metabolizing+Enzymes+that+may+Affect+Response+to+Environmental+Toxicants.&rft.au=Johns%2C+D%3BGuyton%2C+K+Z%3BSonawane%2C+B%3BGinsberg%2C+G&rft.aulast=Johns&rft.aufirst=D&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Integrated Risk Information System Health Assessment of PBDE Congeners. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841395; 4812446 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Donohue, J M AU - Galal-Gorchev, H AU - Jones, S J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Information systems KW - Congeners KW - Brominated hydrocarbons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Integrated+Risk+Information+System+Health+Assessment+of+PBDE+Congeners.&rft.au=Donohue%2C+J+M%3BGalal-Gorchev%2C+H%3BJones%2C+S+J&rft.aulast=Donohue&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling the Pharmacokinetics of Perfluorooctanoic Acid during Gestation and Lactation in Mice. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841311; 4812435 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Rodriguez, C E AU - Barton, H A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Mice KW - Pharmacokinetics KW - Perfluorooctanoic acid KW - Lactation KW - Gestation KW - Pregnancy KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841311?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Modeling+the+Pharmacokinetics+of+Perfluorooctanoic+Acid+during+Gestation+and+Lactation+in+Mice.&rft.au=Rodriguez%2C+C+E%3BBarton%2C+H+A&rft.aulast=Rodriguez&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Characterization of CYPS in the Metabolism of All Trans Retinoic Acid by Liver Microsomes from Mice Treated with Conazoles. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841277; 4812411 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Chen, P AU - Padgett, W T AU - Tanya, M AU - Winnik, W AU - Thai, S AU - Hester, S D AU - Nesnow, S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Metabolism KW - Mice KW - Liver KW - Retinoic acid KW - Microsomes KW - Ribosomes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841277?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Characterization+of+CYPS+in+the+Metabolism+of+All+Trans+Retinoic+Acid+by+Liver+Microsomes+from+Mice+Treated+with+Conazoles.&rft.au=Chen%2C+P%3BPadgett%2C+W+T%3BTanya%2C+M%3BWinnik%2C+W%3BThai%2C+S%3BHester%2C+S+D%3BNesnow%2C+S&rft.aulast=Chen&rft.aufirst=P&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identification of Early Molecular Events Upon Peroxisome Proliferator Exposure in the Rodent Liver. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40841085; 4812520 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Ren, H AU - Vallanat, B AU - Corton, J C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Liver KW - Rodents KW - Peroxisomes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40841085?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Identification+of+Early+Molecular+Events+Upon+Peroxisome+Proliferator+Exposure+in+the+Rodent+Liver.&rft.au=Ren%2C+H%3BVallanat%2C+B%3BCorton%2C+J+C&rft.aulast=Ren&rft.aufirst=H&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Data for the Development of Drinking Water Health Advisory for N-Nitrosodimethylamine. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40840908; 4812460 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Kueberuwa, S S AU - Davidson, K A AU - Opresko, D M Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Drinking water KW - N-Nitrosodimethylamine KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40840908?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Data+for+the+Development+of+Drinking+Water+Health+Advisory+for+N-Nitrosodimethylamine.&rft.au=Kueberuwa%2C+S+S%3BDavidson%2C+K+A%3BOpresko%2C+D+M&rft.aulast=Kueberuwa&rft.aufirst=S&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sodium Dimethyldithiocarbamate (DMDC) Effects on GnRH Neuronal Activation and the Luteinizing Hormone Surge. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40840902; 4812722 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Goldman, J M AU - Murr, A S AU - Cooper, R L AU - Buckalew, A R Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Sodium KW - Hormones KW - Gonadotropin-releasing hormone KW - Luteinizing hormone KW - Surges KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40840902?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Sodium+Dimethyldithiocarbamate+%28DMDC%29+Effects+on+GnRH+Neuronal+Activation+and+the+Luteinizing+Hormone+Surge.&rft.au=Goldman%2C+J+M%3BMurr%2C+A+S%3BCooper%2C+R+L%3BBuckalew%2C+A+R&rft.aulast=Goldman&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Understanding Mode of Action Data and Uncertainty in the Characterization of Cancer Risk Associated with Naphthalene-Induced Toxicity. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40840183; 4812449 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Backus, G S AU - McClure, P AU - Keshava, C AU - Flowers, L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Cancer KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40840183?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Understanding+Mode+of+Action+Data+and+Uncertainty+in+the+Characterization+of+Cancer+Risk+Associated+with+Naphthalene-Induced+Toxicity.&rft.au=Backus%2C+G+S%3BMcClure%2C+P%3BKeshava%2C+C%3BFlowers%2C+L&rft.aulast=Backus&rft.aufirst=G&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Microcystin-LR: Suggestive Evidence of Carcinogenicity. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40840160; 4812456 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Hawkins, B S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Carcinogenicity KW - Microcystin-LR KW - Biological poisons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40840160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Microcystin-LR%3A+Suggestive+Evidence+of+Carcinogenicity.&rft.au=Hawkins%2C+B+S&rft.aulast=Hawkins&rft.aufirst=B&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Technical Challenges Associated with Assessing the In Vitro Pulmonary Toxicity of Carbon Nanotubes T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40840029; 4812161 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Snyder, R J AU - Zucker, R AU - Jaskot, R AU - Dreher, K Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Nanotechnology KW - Carbon KW - Lung KW - Nanotubes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40840029?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Technical+Challenges+Associated+with+Assessing+the+In+Vitro+Pulmonary+Toxicity+of+Carbon+Nanotubes&rft.au=Snyder%2C+R+J%3BZucker%2C+R%3BJaskot%2C+R%3BDreher%2C+K&rft.aulast=Snyder&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differences in Metabolism and Aromatase Activity in a Fish and a Rat Species Treated with Atrazine. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40840017; 4812410 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Mills, L J AU - Gutjahr-Gobell, R AU - Jayaraman, S AU - Zaroogian, G AU - Laws, S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Metabolism KW - Atrazine KW - Herbicides KW - Aromatase KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40840017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Differences+in+Metabolism+and+Aromatase+Activity+in+a+Fish+and+a+Rat+Species+Treated+with+Atrazine.&rft.au=Mills%2C+L+J%3BGutjahr-Gobell%2C+R%3BJayaraman%2C+S%3BZaroogian%2C+G%3BLaws%2C+S&rft.aulast=Mills&rft.aufirst=L&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mechanisms of Nanodiamond Particle Induced IL-8 Expression in Human Airway Epithelial Cells T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839888; 4812146 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Silbajoris, R AU - Huang, M AU - Cheng, W AU - Dailey, L A AU - Saxena, R K AU - Bromberg, P A AU - Samet, J M Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Particulates KW - Epithelial cells KW - Interleukin 8 KW - Respiratory tract KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839888?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Mechanisms+of+Nanodiamond+Particle+Induced+IL-8+Expression+in+Human+Airway+Epithelial+Cells&rft.au=Silbajoris%2C+R%3BHuang%2C+M%3BCheng%2C+W%3BDailey%2C+L+A%3BSaxena%2C+R+K%3BBromberg%2C+P+A%3BSamet%2C+J+M&rft.aulast=Silbajoris&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Aging on the Cardiovascular and Thermoregulatory Response to Toluene in the Brown Norway Rat T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839873; 4812127 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Gordon, C J AU - Becker, P AU - Mack, C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Norway KW - Aging KW - Toluene KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839873?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Effects+of+Aging+on+the+Cardiovascular+and+Thermoregulatory+Response+to+Toluene+in+the+Brown+Norway+Rat&rft.au=Gordon%2C+C+J%3BBecker%2C+P%3BMack%2C+C&rft.aulast=Gordon&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Molecular and Genomic Insights into the Nrf2-Regulated Oxidative Stress Response: Impact on Carcinogenesis. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839773; 4813383 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Corton, C AU - Kensler, T Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Carcinogenesis KW - Oxidative stress KW - Genomics KW - Ecosystem disturbance KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839773?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Molecular+and+Genomic+Insights+into+the+Nrf2-Regulated+Oxidative+Stress+Response%3A+Impact+on+Carcinogenesis.&rft.au=Corton%2C+C%3BKensler%2C+T&rft.aulast=Corton&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Iprodione Delays Male Rat Pubertal Development, Reducing Serum Testosterone and Ex Vivo Testosterone Production. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839751; 4812727 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Blystone, C R AU - Lambright, C S AU - Cardon, M C AU - Furr, J AU - Wilson, V S AU - Gray, L E Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Testosterone KW - Iprodione KW - Sex hormones KW - Serum KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Iprodione+Delays+Male+Rat+Pubertal+Development%2C+Reducing+Serum+Testosterone+and+Ex+Vivo+Testosterone+Production.&rft.au=Blystone%2C+C+R%3BLambright%2C+C+S%3BCardon%2C+M+C%3BFurr%2C+J%3BWilson%2C+V+S%3BGray%2C+L+E&rft.aulast=Blystone&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Pulmonary Toxicity Testing of Nanoparticles. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839659; 4813517 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Lai, D Y Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity testing KW - Lung KW - Nanoparticles KW - Bioaccumulation KW - Pollution indicators KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839659?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Pulmonary+Toxicity+Testing+of+Nanoparticles.&rft.au=Lai%2C+D+Y&rft.aulast=Lai&rft.aufirst=D&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Disposition and Health Effects of Chlorotriazine Metabolites in the Pregnant Rat and her Offspring. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839548; 4813475 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Fenton, S E AU - Rayner, J L AU - Stanko, J P AU - Barr, D L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Offspring KW - Metabolites KW - Progeny KW - Disposition KW - Pregnancy KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839548?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Disposition+and+Health+Effects+of+Chlorotriazine+Metabolites+in+the+Pregnant+Rat+and+her+Offspring.&rft.au=Fenton%2C+S+E%3BRayner%2C+J+L%3BStanko%2C+J+P%3BBarr%2C+D+L&rft.aulast=Fenton&rft.aufirst=S&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Propiconazole-Induced Carcinogenesis: Role of Oxidative Stress. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839396; 4812257 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Bruno, M E AU - Chen, P AU - Moore, T AU - Nesnow, S AU - Ge, Y. Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Oxidative stress KW - Carcinogenesis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839396?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Propiconazole-Induced+Carcinogenesis%3A+Role+of+Oxidative+Stress.&rft.au=Bruno%2C+M+E%3BChen%2C+P%3BMoore%2C+T%3BNesnow%2C+S%3BGe%2C+Y.&rft.aulast=Bruno&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Application of the 10% Minimum Elicitation Threshold to Quantitative Assessment of Dermal Sensitization Risk to Hexavalent Chromium using the Repeat Open Application Test in Humans. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40839166; 4812543 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - McMahon, T AU - Chen, J AU - Liccione, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Chromium KW - Skin KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40839166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Application+of+the+10%25+Minimum+Elicitation+Threshold+to+Quantitative+Assessment+of+Dermal+Sensitization+Risk+to+Hexavalent+Chromium+using+the+Repeat+Open+Application+Test+in+Humans.&rft.au=McMahon%2C+T%3BChen%2C+J%3BLiccione%2C+J&rft.aulast=McMahon&rft.aufirst=T&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Influence of Particulate Air Pollutants on Allergic Sensitization in Animal Models. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40838955; 4813499 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Gilmour, M Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Particulates KW - Animal models KW - Air pollution KW - Pollutants KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40838955?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=The+Influence+of+Particulate+Air+Pollutants+on+Allergic+Sensitization+in+Animal+Models.&rft.au=Gilmour%2C+M&rft.aulast=Gilmour&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Toxicology and Senescence: Baseline Variability and Toluene Effects on Motor Function in Aging Brown Norway Rats. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40838933; 4812481 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - MacPhail, R C AU - Farmer, J D AU - Jarema, K A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Norway KW - Aging KW - Senescence KW - Toluene KW - Toxicology KW - Rats KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40838933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Toxicology+and+Senescence%3A+Baseline+Variability+and+Toluene+Effects+on+Motor+Function+in+Aging+Brown+Norway+Rats.&rft.au=MacPhail%2C+R+C%3BFarmer%2C+J+D%3BJarema%2C+K+A&rft.aulast=MacPhail&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of Toxicity Associated with Oral Exposure to Chlordecone: Comparison of Points of Departure for use in the Derivation of an Oral Reference Dose (RfD). T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40838825; 4812453 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Newhouse, K AU - Berner, T AU - Mukerjee, D AU - Follansbee, M Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Chlordecone KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40838825?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Evaluation+of+Toxicity+Associated+with+Oral+Exposure+to+Chlordecone%3A+Comparison+of+Points+of+Departure+for+use+in+the+Derivation+of+an+Oral+Reference+Dose+%28RfD%29.&rft.au=Newhouse%2C+K%3BBerner%2C+T%3BMukerjee%2C+D%3BFollansbee%2C+M&rft.aulast=Newhouse&rft.aufirst=K&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Quantitative Model for Xenobiotic Metabolizing Enzyme (XME) Induction Regulated by the Pregnane X Receptor (PXR). T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40838739; 4812432 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Luke, N S AU - DeVito, M J AU - Shah, I AU - El-Masri, H Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Xenobiotics KW - Enzymes KW - Pregnane X receptors KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40838739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=A+Quantitative+Model+for+Xenobiotic+Metabolizing+Enzyme+%28XME%29+Induction+Regulated+by+the+Pregnane+X+Receptor+%28PXR%29.&rft.au=Luke%2C+N+S%3BDeVito%2C+M+J%3BShah%2C+I%3BEl-Masri%2C+H&rft.aulast=Luke&rft.aufirst=N&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Where Do We Stand on Chlorotriazine Residuals? Current State of the Science and Regulation. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40838362; 4813474 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Mahfouz, A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Herbicides KW - Disposition KW - Degradation products KW - Chlorophyll KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40838362?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Where+Do+We+Stand+on+Chlorotriazine+Residuals%3F+Current+State+of+the+Science+and+Regulation.&rft.au=Mahfouz%2C+A&rft.aulast=Mahfouz&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Current and Future Use of Mechanistically-Based Models and Mode of Action in Human Health Risk Assessment. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40838301; 4813503 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Sams, R AU - Keshava, N AU - El-Masri, H Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Risk assessment KW - Models KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40838301?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Current+and+Future+Use+of+Mechanistically-Based+Models+and+Mode+of+Action+in+Human+Health+Risk+Assessment.&rft.au=Sams%2C+R%3BKeshava%2C+N%3BEl-Masri%2C+H&rft.aulast=Sams&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Proteomics in Ecotoxicology: Protein Expression Profiling to Screen Chemicals for Androgenic Activity. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40838085; 4812300 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Hemmer, M J AU - Salinas, K A AU - Harris, P A AU - Ng, J W AU - Walker, C C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Ecotoxicology KW - Chemicals KW - Proteomics KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40838085?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Proteomics+in+Ecotoxicology%3A+Protein+Expression+Profiling+to+Screen+Chemicals+for+Androgenic+Activity.&rft.au=Hemmer%2C+M+J%3BSalinas%2C+K+A%3BHarris%2C+P+A%3BNg%2C+J+W%3BWalker%2C+C+C&rft.aulast=Hemmer&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects on Hepatic Deiodinase 1 and Thyroid Hormone Levels in Perinatally Exposed Rats to a PBDE Commercial Mixture. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837852; 4812745 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Szabo, D T AU - Richardson, V M AU - Diliberto, J J AU - Ross, D AU - Kodavanti, P AU - Birnbaum, L S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Hormones KW - Thyroid hormones KW - Rats KW - Iodide peroxidase KW - Liver KW - Brominated hydrocarbons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837852?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Effects+on+Hepatic+Deiodinase+1+and+Thyroid+Hormone+Levels+in+Perinatally+Exposed+Rats+to+a+PBDE+Commercial+Mixture.&rft.au=Szabo%2C+D+T%3BRichardson%2C+V+M%3BDiliberto%2C+J+J%3BRoss%2C+D%3BKodavanti%2C+P%3BBirnbaum%2C+L+S&rft.aulast=Szabo&rft.aufirst=D&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Exacerbation of Atherosclerosis Following Exposure to Various Combustion Source Particles T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837608; 4811992 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Floyd, H S AU - Haykal-Coates, N AU - Dreher, K L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Particulates KW - Combustion KW - Arteriosclerosis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837608?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Exacerbation+of+Atherosclerosis+Following+Exposure+to+Various+Combustion+Source+Particles&rft.au=Floyd%2C+H+S%3BHaykal-Coates%2C+N%3BDreher%2C+K+L&rft.aulast=Floyd&rft.aufirst=H&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Drug Effects on the Locomotor Activity of Larval Zebrafish T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837439; 4811944 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Irons, T D AU - MacPhail, R AU - Hunter, D L AU - Padilla, S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Larvae KW - Drugs KW - Locomotor activity KW - Freshwater fish KW - Danio rerio KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837439?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Drug+Effects+on+the+Locomotor+Activity+of+Larval+Zebrafish&rft.au=Irons%2C+T+D%3BMacPhail%2C+R%3BHunter%2C+D+L%3BPadilla%2C+S&rft.aulast=Irons&rft.aufirst=T&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Incorporation of Mode of Action into Mechanistically-Based Quantitative Models. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837374; 4813504 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Keshava, N AU - El-Masri, H Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837374?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Incorporation+of+Mode+of+Action+into+Mechanistically-Based+Quantitative+Models.&rft.au=Keshava%2C+N%3BEl-Masri%2C+H&rft.aulast=Keshava&rft.aufirst=N&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of Genomics Data at the US EPA for Predictive and Mechanistic Toxicology. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837304; 4813488 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Dix, D J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - EPA KW - Toxicology KW - Genomics KW - Prediction KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837304?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Use+of+Genomics+Data+at+the+US+EPA+for+Predictive+and+Mechanistic+Toxicology.&rft.au=Dix%2C+D+J&rft.aulast=Dix&rft.aufirst=D&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Residential Pesticide Study: Evaluation of Residual Organochlorine Pesticides Around Residential Properties in California. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837249; 4812478 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Bosan, W AU - Jones, J AU - Oudiz, D AU - Morris, R AU - Hinojosa, J AU - Fair, S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - USA, California KW - Pesticides (organochlorine) KW - Organochlorine compounds KW - Chlorine compounds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Residential+Pesticide+Study%3A+Evaluation+of+Residual+Organochlorine+Pesticides+Around+Residential+Properties+in+California.&rft.au=Bosan%2C+W%3BJones%2C+J%3BOudiz%2C+D%3BMorris%2C+R%3BHinojosa%2C+J%3BFair%2C+S&rft.aulast=Bosan&rft.aufirst=W&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Comparison of Animal and Human Data Used in Deriving a Carbon Tetrachloride Reference Concentration. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837216; 4812451 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Rieth, S AU - Scott, C S AU - Cooper, G S Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Carbon tetrachloride KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837216?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=A+Comparison+of+Animal+and+Human+Data+Used+in+Deriving+a+Carbon+Tetrachloride+Reference+Concentration.&rft.au=Rieth%2C+S%3BScott%2C+C+S%3BCooper%2C+G+S&rft.aulast=Rieth&rft.aufirst=S&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of a Peri-Juvenille Exposure of 2,4-Dichlorophenoxyacetic Acid (2,4-D) on Thyroid Function and Reproductive Development in the Male Wistar Rat. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40837118; 4812732 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Stoker, T AU - Zorrilla, L AU - Jeffay, S AU - Cooper, R AU - Gibson, E Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - 2,4-Dichlorophenoxyacetic acid KW - Thyroid KW - 2,4-D KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40837118?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Effect+of+a+Peri-Juvenille+Exposure+of+2%2C4-Dichlorophenoxyacetic+Acid+%282%2C4-D%29+on+Thyroid+Function+and+Reproductive+Development+in+the+Male+Wistar+Rat.&rft.au=Stoker%2C+T%3BZorrilla%2C+L%3BJeffay%2C+S%3BCooper%2C+R%3BGibson%2C+E&rft.aulast=Stoker&rft.aufirst=T&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Determination of a Southern California Regional Background Arsenic Concentration in Soil T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40836840; 4812839 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Chernoff, G AU - Bosan, W AU - Oudiz, D Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - USA, California KW - Soil KW - Arsenic KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40836840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Determination+of+a+Southern+California+Regional+Background+Arsenic+Concentration+in+Soil&rft.au=Chernoff%2C+G%3BBosan%2C+W%3BOudiz%2C+D&rft.aulast=Chernoff&rft.aufirst=G&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Full-Genome Analysis of Alternative Splicing in Mouse Liver after Hepatotoxicant Exposure. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40836744; 4812663 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Vallanat, B AU - Lee, J S AU - Ward, W AU - Ren, H AU - Rosen, M AU - Hester, S AU - Nesnow, S AU - Lau, C AU - Delker, D AU - Corton, J C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Liver KW - Alternative splicing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40836744?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Full-Genome+Analysis+of+Alternative+Splicing+in+Mouse+Liver+after+Hepatotoxicant+Exposure.&rft.au=Vallanat%2C+B%3BLee%2C+J+S%3BWard%2C+W%3BRen%2C+H%3BRosen%2C+M%3BHester%2C+S%3BNesnow%2C+S%3BLau%2C+C%3BDelker%2C+D%3BCorton%2C+J+C&rft.aulast=Vallanat&rft.aufirst=B&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Xenobiotic Metabolism Research and its Application to Human and Ecological Exposure and Risk Assessment. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40836391; 4812513 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Kenneke, J F AU - Mazur, C S AU - Henderson, W M AU - Garrison, A W AU - Ritger, S E AU - Sack, T J AU - Brown, C C AU - Avants, J K Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Risk assessment KW - Metabolism KW - Xenobiotics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40836391?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Xenobiotic+Metabolism+Research+and+its+Application+to+Human+and+Ecological+Exposure+and+Risk+Assessment.&rft.au=Kenneke%2C+J+F%3BMazur%2C+C+S%3BHenderson%2C+W+M%3BGarrison%2C+A+W%3BRitger%2C+S+E%3BSack%2C+T+J%3BBrown%2C+C+C%3BAvants%2C+J+K&rft.aulast=Kenneke&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of Iron Sequestration in Host Response to Particles and Fibers. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40835408; 4813396 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Ghio, A J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Particulates KW - Fibers KW - Iron KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40835408?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Role+of+Iron+Sequestration+in+Host+Response+to+Particles+and+Fibers.&rft.au=Ghio%2C+A+J&rft.aulast=Ghio&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Neurotoxicants on Proliferation and Viability of Immortalized Human Cortical Neural Progenitor Cells. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40835194; 4813391 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Breier, J M AU - Mundy, W R AU - Shafer, T J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Cell proliferation KW - Neural stem cells KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40835194?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Effects+of+Neurotoxicants+on+Proliferation+and+Viability+of+Immortalized+Human+Cortical+Neural+Progenitor+Cells.&rft.au=Breier%2C+J+M%3BMundy%2C+W+R%3BShafer%2C+T+J&rft.aulast=Breier&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Aorta, but Not Lung or Heart, is the Target of Subchronic Diesel-Induced Injury and Inflammation T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40835077; 4812006 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Thomas, R AU - Schladweiler, M C AU - Ledbetter, A D AU - Shannahan, J AU - Wallenborn, J AU - Nyska, A AU - Malarkey, D AU - Richards, J H AU - Jaskot, R AU - Kodavanti, U P Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Lung KW - Injuries KW - Heart KW - Inflammation KW - Aorta KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40835077?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=The+Aorta%2C+but+Not+Lung+or+Heart%2C+is+the+Target+of+Subchronic+Diesel-Induced+Injury+and+Inflammation&rft.au=Thomas%2C+R%3BSchladweiler%2C+M+C%3BLedbetter%2C+A+D%3BShannahan%2C+J%3BWallenborn%2C+J%3BNyska%2C+A%3BMalarkey%2C+D%3BRichards%2C+J+H%3BJaskot%2C+R%3BKodavanti%2C+U+P&rft.aulast=Thomas&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evidence of Autoimmune-Related Effects of Trichloroethylene in Studies in Mice and Humans. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40834821; 4812322 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Cooper, G S AU - Makris, S L AU - Jinot, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Solvents KW - Mice KW - Trichloroethylene KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40834821?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Evidence+of+Autoimmune-Related+Effects+of+Trichloroethylene+in+Studies+in+Mice+and+Humans.&rft.au=Cooper%2C+G+S%3BMakris%2C+S+L%3BJinot%2C+J&rft.aulast=Cooper&rft.aufirst=G&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Acute Exposure to Particulate Matter (PM) in a Rat Model of Heart Failure T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40834813; 4812013 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Carll, A P AU - Haykal-Coates, N AU - Winsett, D W AU - Rowan, W H AU - Ledbetter, A D AU - Richards, J H AU - Farraj, A K AU - Costa, D L AU - Watkinson, W P Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Particulate matter KW - Heart diseases KW - Suspended particulate matter KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40834813?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Acute+Exposure+to+Particulate+Matter+%28PM%29+in+a+Rat+Model+of+Heart+Failure&rft.au=Carll%2C+A+P%3BHaykal-Coates%2C+N%3BWinsett%2C+D+W%3BRowan%2C+W+H%3BLedbetter%2C+A+D%3BRichards%2C+J+H%3BFarraj%2C+A+K%3BCosta%2C+D+L%3BWatkinson%2C+W+P&rft.aulast=Carll&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Benzo[a]Pyrene-7,8-Quinone Forms Covalent-DNA Adducts In Vitro but None Were Detected in the Lungs or Livers of Strain A/J Mice In Vivo. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40834759; 4812246 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Nesnow, S AU - Padgett, W AU - Nelson, G AU - Winnik, W AU - Lambert, G AU - George, M H AU - Ross, J A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Lung KW - Mice KW - Liver KW - Adducts KW - Strains KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40834759?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Benzo%5Ba%5DPyrene-7%2C8-Quinone+Forms+Covalent-DNA+Adducts+In+Vitro+but+None+Were+Detected+in+the+Lungs+or+Livers+of+Strain+A%2FJ+Mice+In+Vivo.&rft.au=Nesnow%2C+S%3BPadgett%2C+W%3BNelson%2C+G%3BWinnik%2C+W%3BLambert%2C+G%3BGeorge%2C+M+H%3BRoss%2C+J+A&rft.aulast=Nesnow&rft.aufirst=S&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparing Gene Expression Patterns in Blood and Lung Tissue of Immunologically-Challenged Rats Exposed to Concentrated Airborne Particulates T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40833493; 4812830 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Reif, D AU - Heidenfelder, B AU - Hubal, E AU - Harkema, J R AU - Gallagher, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Airborne particulates KW - Lung KW - Rats KW - Gene expression KW - Blood KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40833493?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Comparing+Gene+Expression+Patterns+in+Blood+and+Lung+Tissue+of+Immunologically-Challenged+Rats+Exposed+to+Concentrated+Airborne+Particulates&rft.au=Reif%2C+D%3BHeidenfelder%2C+B%3BHubal%2C+E%3BHarkema%2C+J+R%3BGallagher%2C+J&rft.aulast=Reif&rft.aufirst=D&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - ToxRefDB: Classifying ToxCast Phase I Chemicals Utilizing Structured Toxicity Information T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40833241; 4811461 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Martin, M T AU - Judson, R AU - McLaurin, K AU - Rotroff, D AU - Dellarco, V AU - Mendez, E AU - Reaves, M AU - Dix, D J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Chemicals KW - Information processing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40833241?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=ToxRefDB%3A+Classifying+ToxCast+Phase+I+Chemicals+Utilizing+Structured+Toxicity+Information&rft.au=Martin%2C+M+T%3BJudson%2C+R%3BMcLaurin%2C+K%3BRotroff%2C+D%3BDellarco%2C+V%3BMendez%2C+E%3BReaves%2C+M%3BDix%2C+D+J&rft.aulast=Martin&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Functionally Charged Nanosize Particles Differentially Activate BV2 Microglia T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40833114; 4812204 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Veronesi, B AU - Liu, L AU - Hester, S AU - Ward, W AU - Tajuba, J AU - Pooler, M AU - Swartz, C AU - Saleh, N AU - Lowry, G V AU - Simon, S A Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Particulates KW - Microglia KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40833114?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Functionally+Charged+Nanosize+Particles+Differentially+Activate+BV2+Microglia&rft.au=Veronesi%2C+B%3BLiu%2C+L%3BHester%2C+S%3BWard%2C+W%3BTajuba%2C+J%3BPooler%2C+M%3BSwartz%2C+C%3BSaleh%2C+N%3BLowry%2C+G+V%3BSimon%2C+S+A&rft.aulast=Veronesi&rft.aufirst=B&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Changes in mRNA Expression Profiles in Rat Cortex and Striatum Following Sub-Chronic Toluene Exposure T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832858; 4811389 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Johnstone, A F AU - Hester, S D AU - Boyes, W K AU - Bushnell, P J AU - Meacham, C A AU - Shafer, T J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toluene KW - Gene expression KW - Cortex KW - Neostriatum KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832858?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Changes+in+mRNA+Expression+Profiles+in+Rat+Cortex+and+Striatum+Following+Sub-Chronic+Toluene+Exposure&rft.au=Johnstone%2C+A+F%3BHester%2C+S+D%3BBoyes%2C+W+K%3BBushnell%2C+P+J%3BMeacham%2C+C+A%3BShafer%2C+T+J&rft.aulast=Johnstone&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Acute Inhalation of 2,2,4-trimethylpentane Alters Visual Evoked Potentials and Signal Detection Behavior of Rats T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832785; 4811370 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Boyes, W K AU - Degn, L L AU - Bercegeay, M AU - Oshiro, W AU - Krantz, T AU - Bushnell, P J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Inhalation KW - Rats KW - Visual evoked potentials KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Acute+Inhalation+of+2%2C2%2C4-trimethylpentane+Alters+Visual+Evoked+Potentials+and+Signal+Detection+Behavior+of+Rats&rft.au=Boyes%2C+W+K%3BDegn%2C+L+L%3BBercegeay%2C+M%3BOshiro%2C+W%3BKrantz%2C+T%3BBushnell%2C+P+J&rft.aulast=Boyes&rft.aufirst=W&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Carbaryl-Induced Cholinesterase Inhibition and Dosimetry in Young and Adult Rats T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832752; 4811278 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Moser, V C AU - Phillips, P M AU - McDaniel, K L AU - Graff, J E AU - Lowit, A B AU - Reaves, E AU - Setzer, W AU - Herr, D W Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Cholinesterase KW - Rats KW - Dosimetry KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832752?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Carbaryl-Induced+Cholinesterase+Inhibition+and+Dosimetry+in+Young+and+Adult+Rats&rft.au=Moser%2C+V+C%3BPhillips%2C+P+M%3BMcDaniel%2C+K+L%3BGraff%2C+J+E%3BLowit%2C+A+B%3BReaves%2C+E%3BSetzer%2C+W%3BHerr%2C+D+W&rft.aulast=Moser&rft.aufirst=V&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Changes in Mitogen-Activated Protein Kinase in Cerebellar Granule Neuronal Cultures by Polybrominated Diphenyl Ethers. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832389; 4812570 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Fan, C AU - Kodavanti, P R Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Polybrominated diphenyl ethers KW - MAP kinase KW - Cerebellum KW - Granules KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832389?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Changes+in+Mitogen-Activated+Protein+Kinase+in+Cerebellar+Granule+Neuronal+Cultures+by+Polybrominated+Diphenyl+Ethers.&rft.au=Fan%2C+C%3BKodavanti%2C+P+R&rft.aulast=Fan&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Expression Profiling of Five Rat Strains Reveal Transcriptional Modes in the Antigen Processing Pathway T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832354; 4811506 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Ward, W AU - Schladweiler, M AU - Ledbetter, A AU - Kodavanti, U Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Transcription KW - Antigen processing KW - Antigens KW - Profiling KW - Strains KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832354?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Expression+Profiling+of+Five+Rat+Strains+Reveal+Transcriptional+Modes+in+the+Antigen+Processing+Pathway&rft.au=Ward%2C+W%3BSchladweiler%2C+M%3BLedbetter%2C+A%3BKodavanti%2C+U&rft.aulast=Ward&rft.aufirst=W&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Toxicity Data Landscape for Environmental Chemicals T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832277; 4811459 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Judson, R AU - Richard, A AU - Dix, D AU - Houck, K AU - Martin, M AU - Kavlock, R AU - Vicki, D AU - Holderman, T AU - Tan, S AU - Carpenter, T AU - Smith, E Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Chemicals KW - Landscape KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832277?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=The+Toxicity+Data+Landscape+for+Environmental+Chemicals&rft.au=Judson%2C+R%3BRichard%2C+A%3BDix%2C+D%3BHouck%2C+K%3BMartin%2C+M%3BKavlock%2C+R%3BVicki%2C+D%3BHolderman%2C+T%3BTan%2C+S%3BCarpenter%2C+T%3BSmith%2C+E&rft.aulast=Judson&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Recent Developments in the US EPAs Integrated Risk Information System (IRIS) Program. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832124; 4812447 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Kadry, A M AU - Hammerstrom, K AU - Strong, J AU - Vandenberg, J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Information systems KW - EPA KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Recent+Developments+in+the+US+EPAs+Integrated+Risk+Information+System+%28IRIS%29+Program.&rft.au=Kadry%2C+A+M%3BHammerstrom%2C+K%3BStrong%2C+J%3BVandenberg%2C+J&rft.aulast=Kadry&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of a Physiologically-Based Pharmacokinetic (PBPK) Model for the Inhalation of 2,2,4-trimethylpentane (TMP) in Long Evans Rats. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832032; 4812427 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - El-Masri, H A AU - Simmons, J AU - Pegram, R A AU - Harrison, R A AU - Yavanhxay, J AU - Dowd, S AU - Evans, M V Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Inhalation KW - Pharmacokinetics KW - Rats KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Development+of+a+Physiologically-Based+Pharmacokinetic+%28PBPK%29+Model+for+the+Inhalation+of+2%2C2%2C4-trimethylpentane+%28TMP%29+in+Long+Evans+Rats.&rft.au=El-Masri%2C+H+A%3BSimmons%2C+J%3BPegram%2C+R+A%3BHarrison%2C+R+A%3BYavanhxay%2C+J%3BDowd%2C+S%3BEvans%2C+M+V&rft.aulast=El-Masri&rft.aufirst=H&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tolerance to Anatoxin-a and Nicotine on Operant Behavior: A Search for Mechanisms T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40832004; 4811372 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Jarema, K A AU - Farmer, J D AU - MacPhail, R C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Nicotine KW - Operant conditioning KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40832004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Tolerance+to+Anatoxin-a+and+Nicotine+on+Operant+Behavior%3A+A+Search+for+Mechanisms&rft.au=Jarema%2C+K+A%3BFarmer%2C+J+D%3BMacPhail%2C+R+C&rft.aulast=Jarema&rft.aufirst=K&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differential Cardiac Arrhythmia Profiles in Hypertensive and Normal Rats after Emission Source Particulate Exposure T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40831339; 4812014 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Farraj, A K AU - Winsett, D W AU - Haykal-Coates, N AU - Hazari, M S AU - Carll, A P AU - Ledbetter, A D AU - Costa, D L Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Particulates KW - Emissions KW - Rats KW - Arrhythmia KW - Heart KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40831339?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Differential+Cardiac+Arrhythmia+Profiles+in+Hypertensive+and+Normal+Rats+after+Emission+Source+Particulate+Exposure&rft.au=Farraj%2C+A+K%3BWinsett%2C+D+W%3BHaykal-Coates%2C+N%3BHazari%2C+M+S%3BCarll%2C+A+P%3BLedbetter%2C+A+D%3BCosta%2C+D+L&rft.aulast=Farraj&rft.aufirst=A&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - ToxCast: Developing Predictive Signatures of Chemically Induced Toxicity T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40831189; 4811460 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Kavlock, R J AU - Dix, D J AU - Houck, K AU - Judson, R AU - Knudsen, T AU - Martin, M AU - Richard, A AU - Setzer, W Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Prediction KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40831189?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=ToxCast%3A+Developing+Predictive+Signatures+of+Chemically+Induced+Toxicity&rft.au=Kavlock%2C+R+J%3BDix%2C+D+J%3BHouck%2C+K%3BJudson%2C+R%3BKnudsen%2C+T%3BMartin%2C+M%3BRichard%2C+A%3BSetzer%2C+W&rft.aulast=Kavlock&rft.aufirst=R&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Application of in Silico Toxicant-Target Approach to Screening a Chemical Library for Estrogenicity T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40830624; 4811470 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Rabinowitz, J AU - Little, S AU - Goldsmith, M Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Estrogens KW - Screening KW - Sex hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40830624?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Application+of+in+Silico+Toxicant-Target+Approach+to+Screening+a+Chemical+Library+for+Estrogenicity&rft.au=Rabinowitz%2C+J%3BLittle%2C+S%3BGoldsmith%2C+M&rft.aulast=Rabinowitz&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Acute Behavioral Effects of Inhaled Perchloroethylene in Rats are Directly Related to its Concentration in the Brain. T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40830322; 4811369 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Oshiro, W M AU - Krantz, Q T AU - Kenyon, E M AU - Bushnell, P J Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Perchloroethylene KW - Brain KW - Rats KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40830322?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Acute+Behavioral+Effects+of+Inhaled+Perchloroethylene+in+Rats+are+Directly+Related+to+its+Concentration+in+the+Brain.&rft.au=Oshiro%2C+W+M%3BKrantz%2C+Q+T%3BKenyon%2C+E+M%3BBushnell%2C+P+J&rft.aulast=Oshiro&rft.aufirst=W&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A QSTR Analysis of CWAs Using Commercial QSTR Models: DEREK and TOPKAT T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40828206; 4811471 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Moudgal, C J AU - Sparks, M Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40828206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=A+QSTR+Analysis+of+CWAs+Using+Commercial+QSTR+Models%3A+DEREK+and+TOPKAT&rft.au=Moudgal%2C+C+J%3BSparks%2C+M&rft.aulast=Moudgal&rft.aufirst=C&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gene Expression Profiling of Xenobiotic Metabolizing Enzymes (XMEs) through the Life Stages of the Male C57BL/6 Mouse T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40827992; 4811403 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Lee, J S AU - Ward, W AU - Ren, H AU - Grindstaff, R AU - George, M AU - Delker, D AU - Corton, J C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Xenobiotics KW - Enzymes KW - Gene expression KW - Developmental stages KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40827992?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Gene+Expression+Profiling+of+Xenobiotic+Metabolizing+Enzymes+%28XMEs%29+through+the+Life+Stages+of+the+Male+C57BL%2F6+Mouse&rft.au=Lee%2C+J+S%3BWard%2C+W%3BRen%2C+H%3BGrindstaff%2C+R%3BGeorge%2C+M%3BDelker%2C+D%3BCorton%2C+J+C&rft.aulast=Lee&rft.aufirst=J&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In Silico Studies of the ToxCast Chemicals Interacting with Biomolecular Targets T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40827088; 4811469 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Goldsmith, M R AU - Little, S B AU - Houck, K A AU - Dix, D J AU - Rabinowitz, J R Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Chemicals KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40827088?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=In+Silico+Studies+of+the+ToxCast+Chemicals+Interacting+with+Biomolecular+Targets&rft.au=Goldsmith%2C+M+R%3BLittle%2C+S+B%3BHouck%2C+K+A%3BDix%2C+D+J%3BRabinowitz%2C+J+R&rft.aulast=Goldsmith&rft.aufirst=M&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An in Silico Approach to Assessing Risk of 1-bromo-2-chloroethane T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40826312; 4811480 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Wang, N Y AU - Lambert, J C Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Bioinformatics KW - Toxicology KW - Computer applications KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40826312?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=An+in+Silico+Approach+to+Assessing+Risk+of+1-bromo-2-chloroethane&rft.au=Wang%2C+N+Y%3BLambert%2C+J+C&rft.aulast=Wang&rft.aufirst=N&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Computational Framework for Systems-Based Analysis of Developmental Toxicity T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40826237; 4811462 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Knudsen, T B AU - Singh, A V AU - Kavlock, R J AU - Dix, D J AU - Judson, R S AU - Martin, M T AU - Dellarco, V L AU - Mendez, E AU - Reaves, E Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Computer applications KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40826237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Computational+Framework+for+Systems-Based+Analysis+of+Developmental+Toxicity&rft.au=Knudsen%2C+T+B%3BSingh%2C+A+V%3BKavlock%2C+R+J%3BDix%2C+D+J%3BJudson%2C+R+S%3BMartin%2C+M+T%3BDellarco%2C+V+L%3BMendez%2C+E%3BReaves%2C+E&rft.aulast=Knudsen&rft.aufirst=T&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Subchronic Toxicity of Inhaled Toluene in Rats: Oxidative Stress Markers in Brain T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40825744; 4811543 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Moore-Smith, D A AU - Richards, J H AU - Samsam, T E AU - Evansky, P AU - Bushnell, P J AU - Kodavanti, P R Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Toxicity KW - Brain KW - Toluene KW - Oxidative stress KW - Rats KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40825744?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Subchronic+Toxicity+of+Inhaled+Toluene+in+Rats%3A+Oxidative+Stress+Markers+in+Brain&rft.au=Moore-Smith%2C+D+A%3BRichards%2C+J+H%3BSamsam%2C+T+E%3BEvansky%2C+P%3BBushnell%2C+P+J%3BKodavanti%2C+P+R&rft.aulast=Moore-Smith&rft.aufirst=D&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Proteomic Profiling of Cultured Human Bladder Cells after Trivalent Arsenical Exposures T2 - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AN - 40825657; 4811519 JF - 47th Annual Meeting of the Society of Toxicology (SOT 2008) AU - Ortiz, P A AU - Wallace, K AU - Winnik, W Y1 - 2008/03/16/ PY - 2008 DA - 2008 Mar 16 KW - Proteomics KW - Urinary bladder KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40825657?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.atitle=Proteomic+Profiling+of+Cultured+Human+Bladder+Cells+after+Trivalent+Arsenical+Exposures&rft.au=Ortiz%2C+P+A%3BWallace%2C+K%3BWinnik%2C+W&rft.aulast=Ortiz&rft.aufirst=P&rft.date=2008-03-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=47th+Annual+Meeting+of+the+Society+of+Toxicology+%28SOT+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.toxicology.org/ai/meet/am2008/it_planner.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite. AN - 70376526; 18191166 AB - Chronic drinking water exposure to inorganic arsenic and its metabolites increases tumor frequency in the skin of K6/ODC transgenic mice. To identify potential biomarkers and modes of action for this skin tumorigenicity, we characterized gene expression profiles from analysis of K6/ODC mice administered 0, 0.05, 0.25, 1.0 and 10 ppm sodium arsenite in their drinking water for 4 weeks. Following exposure, total RNA was isolated from mouse skin and processed to biotin-labeled cRNA for microarray analyses. Skin gene expression was analyzed with Affymetrix Mouse Genome 430A 2.0 GeneChips, and pathway analysis was conducted with DAVID (NIH), Ingenuity Systems and MetaCore's GeneGo. Differential expression of several key genes was verified through qPCR. Only the highest dose (10 ppm) resulted in significantly altered KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways, including MAPK, regulation of actin cytoskeleton, Wnt, Jak-Stat, Tight junction, Toll-like, phosphatidylinositol and insulin signaling pathways. Approximately 20 genes exhibited a dose response, including several genes known to be associated with carcinogenesis or tumor progression including cyclin D1, CLIC4, Ephrin A1, STAT3 and DNA methyltransferase 3a. Although transcription changes in all identified genes have not previously been linked to arsenic carcinogenesis, their association with carcinogenesis in other systems suggests that these genes may play a role in the early stages of arsenic-induced skin carcinogenesis and can be considered potential biomarkers. JF - Toxicology and applied pharmacology AU - Ahlborn, Gene J AU - Nelson, Gail M AU - Ward, William O AU - Knapp, Geremy AU - Allen, James W AU - Ouyang, Ming AU - Roop, Barbara C AU - Chen, Yan AU - O'Brien, Thomas AU - Kitchin, Kirk T AU - Delker, Don A AD - United States Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Environmental Carcinogenesis Division, Research Triangle Park, NC 27711, USA. Y1 - 2008/03/15/ PY - 2008 DA - 2008 Mar 15 SP - 400 EP - 416 VL - 227 IS - 3 SN - 0041-008X, 0041-008X KW - Arsenites KW - 0 KW - Sodium Compounds KW - sodium arsenite KW - 48OVY2OC72 KW - Index Medicus KW - Gene Expression -- drug effects KW - Animals KW - Dose-Response Relationship, Drug KW - Mice KW - Mice, Transgenic KW - Skin Neoplasms -- genetics KW - Gene Expression Profiling KW - Skin -- drug effects KW - Skin Neoplasms -- chemically induced KW - Skin -- metabolism KW - Arsenites -- toxicity KW - Sodium Compounds -- toxicity KW - Cell Transformation, Neoplastic -- chemically induced KW - Cell Transformation, Neoplastic -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70376526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Dose+response+evaluation+of+gene+expression+profiles+in+the+skin+of+K6%2FODC+mice+exposed+to+sodium+arsenite.&rft.au=Ahlborn%2C+Gene+J%3BNelson%2C+Gail+M%3BWard%2C+William+O%3BKnapp%2C+Geremy%3BAllen%2C+James+W%3BOuyang%2C+Ming%3BRoop%2C+Barbara+C%3BChen%2C+Yan%3BO%27Brien%2C+Thomas%3BKitchin%2C+Kirk+T%3BDelker%2C+Don+A&rft.aulast=Ahlborn&rft.aufirst=Gene&rft.date=2008-03-15&rft.volume=227&rft.issue=3&rft.spage=400&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.10.029 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-05 N1 - Date created - 2008-03-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2007.10.029 ER - TY - JOUR T1 - Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide. AN - 70372474; 18164361 AB - Conazoles are azole-containing fungicides that are used in agriculture and medicine. Conazoles can induce follicular cell adenomas of the thyroid in rats after chronic bioassay. The goal of this study was to identify pathways and networks of genes that were associated with thyroid tumorigenesis through transcriptional analyses. To this end, we compared transcriptional profiles from tissues of rats treated with a tumorigenic and a non-tumorigenic conazole. Triadimefon, a rat thyroid tumorigen, and myclobutanil, which was not tumorigenic in rats after a 2-year bioassay, were administered in the feed to male Wistar/Han rats for 30 or 90 days similar to the treatment conditions previously used in their chronic bioassays. Thyroid gene expression was determined using high density Affymetrix GeneChips (Rat 230_2). Gene expression was analyzed by the Gene Set Expression Analyses method which clearly separated the tumorigenic treatments (tumorigenic response group (TRG)) from the non-tumorigenic treatments (non-tumorigenic response group (NRG)). Core genes from these gene sets were mapped to canonical, metabolic, and GeneGo processes and these processes compared across group and treatment time. Extensive analyses were performed on the 30-day gene sets as they represented the major perturbations. Gene sets in the 30-day TRG group had over representation of fatty acid metabolism, oxidation, and degradation processes (including PPARgamma and CYP involvement), and of cell proliferation responses. Core genes from these gene sets were combined into networks and found to possess signaling interactions. In addition, the core genes in each gene set were compared with genes known to be associated with human thyroid cancer. Among the genes that appeared in both rat and human data sets were: Acaca, Asns, Cebpg, Crem, Ddit3, Gja1, Grn, Jun, Junb, and Vegf. These genes were major contributors in the previously developed network from triadimefon-treated rat thyroids. It is postulated that triadimefon induces oxidative response genes and activates the nuclear receptor, Ppargamma, initiating transcription of gene products and signaling to a series of genes involved in cell proliferation. JF - Toxicology and applied pharmacology AU - Hester, Susan D AU - Nesnow, Stephen AD - Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. hester.susan@epa.gov Y1 - 2008/03/15/ PY - 2008 DA - 2008 Mar 15 SP - 357 EP - 369 VL - 227 IS - 3 SN - 0041-008X, 0041-008X KW - Antifungal Agents KW - 0 KW - Carcinogens KW - Nitriles KW - Triazoles KW - systhane KW - triadimefon KW - 1HW039CJF0 KW - Index Medicus KW - Rats KW - Animals KW - Transcription, Genetic -- drug effects KW - Oligonucleotide Array Sequence Analysis KW - Rats, Wistar KW - Male KW - Gene Expression Profiling KW - Antifungal Agents -- toxicity KW - Triazoles -- toxicity KW - Thyroid Gland -- drug effects KW - Antifungal Agents -- chemistry KW - Carcinogens -- chemistry KW - Carcinogens -- toxicity KW - Triazoles -- chemistry KW - Nitriles -- toxicity KW - Nitriles -- chemistry KW - Thyroid Gland -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70372474?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Transcriptional+responses+in+thyroid+tissues+from+rats+treated+with+a+tumorigenic+and+a+non-tumorigenic+triazole+conazole+fungicide.&rft.au=Hester%2C+Susan+D%3BNesnow%2C+Stephen&rft.aulast=Hester&rft.aufirst=Susan&rft.date=2008-03-15&rft.volume=227&rft.issue=3&rft.spage=357&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.10.030 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-05 N1 - Date created - 2008-03-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2007.10.030 ER - TY - JOUR T1 - Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDS/PCDFS and PCBS AN - 20565840; 8094509 AB - The toxic equivalency factor (TEF) approach was employed to compare immunotoxic potency of mixtures containing polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls relative to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), using the antibody response to sheep erythrocytes (SRBC). Mixture-1 (MIX-1) contained TCDD, 1,2,3,7,8-pentachlorodibenzo-p-dioxin (PeCDD), 2,3,7,8-tetrachlorodibenzofuran (TCDF), 1,2,3,7,8-pentachlorodibenzofuran (1-PeCDF), 2,3,4,7,8-pentachlorodibenzofuran (4-PeCDF), and 1,2,3,4,6,7,8,9-octachlorodibenzofuran (OCDF). Mixture-2 (MIX-2) contained MIX-1 and the following PCBs, 3,3',4,4'-tetrachlorobiphenyl (IUPAC No. 77), 3,3',4,4',5-pentachlorobiphenyl (126), 3,3',4,4',5,5N-hexachlorobiphenyl (169), 2,3,3',4,4'-pentachlorobiphenyl (105), 2,3',4,4',5-pentachlorobiphenyl (118), and 2,3,3',4,4',5-hexachlorobiphenyl (156). The mixture compositions were based on relative chemical concentrations in food and human tissues. TCDD equivalents (TEQ) of the mixture were estimated using relative potency factors from hepatic enzyme induction in mice [DeVito, M.J., Diliberto, J.J., Ross, D.G., Menache, M.G., Birnbaum, L.S., 1997. Dose-response relationships for polyhalogenated dioxins and dibenzofurans following subchronic treatment in mice. I .CYP1A1 and CYP1A2 enzyme activity in liver, lung and skin. Toxicol. Appl. Pharmacol. 130, 197-208; DeVito, M.J., Menache, G., Diliberto, J.J., Ross, D.G., Birnbaum L.S., 2000. Dose-response relationships for induction of CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin in female mice following subchronic exposure to polychlorinated biphenyls. Toxicol. Appl. Pharmacol. 167, 157-172] Female mice received 0, 1.5, 15, 150 or 450 ng TCDD/kg/day or approximately 0, 1.5, 15, 150 or 450 ng TEQ/kg/day of MIX-1 or MIX-2 by gavage 5 days per week for 13 weeks. Mice were immunized 3 days after the last exposure and 4 days later, body, spleen, thymus, and liver weights were measured, and antibody response to SRBCs was observed. Exposure to TCDD, MIX-1, and MIX-2 suppressed the antibody response in a dose-dependent manner. Two-way ANOVA indicated no differences in the response between TCDD and the mixtures for body weight, spleen /body weight and decreased antibody responses. The results support the use of the TEF methodology and suggest that immune suppression by dioxin-like chemicals may be of concern at or near background human exposures. JF - Toxicology and Applied Pharmacology AU - Smialowicz, R J AU - DeVito, MJ AU - Williams, W C AU - Birnbaum, L S AD - National Health, and Environmental Effects, Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA, devito.mike@epa.gov Y1 - 2008/03/15/ PY - 2008 DA - 2008 Mar 15 SP - 477 EP - 484 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 227 IS - 3 SN - 0041-008X, 0041-008X KW - Pollution Abstracts; Toxicology Abstracts; Immunology Abstracts KW - Food KW - Erythrocytes KW - 3,3',4,4',5-Pentachlorobiphenyl KW - enzymatic activity KW - Dioxins KW - Body weight KW - Dose-response effects KW - PCDF KW - sheep KW - body weight KW - PCB compounds KW - PCDD KW - PCB KW - Skin KW - CYP1A2 protein KW - Thymus KW - Spleen KW - Enzymes KW - TCDD KW - Polychlorinated dibenzofurans KW - Mice KW - Antibody response KW - polychlorinated biphenyls KW - Lung KW - Dibenzofuran KW - Liver KW - Dibenzo-p-dioxin KW - Cytochrome P450 KW - Dioxin KW - Immunosuppression KW - F 06955:Immunomodulation & Immunopharmacology KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20565840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Relative+potency+based+on+hepatic+enzyme+induction+predicts+immunosuppressive+effects+of+a+mixture+of+PCDDS%2FPCDFS+and+PCBS&rft.au=Smialowicz%2C+R+J%3BDeVito%2C+MJ%3BWilliams%2C+W+C%3BBirnbaum%2C+L+S&rft.aulast=Smialowicz&rft.aufirst=R&rft.date=2008-03-15&rft.volume=227&rft.issue=3&rft.spage=477&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.11.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - CYP1A2 protein; Skin; Food; Erythrocytes; Thymus; 3,3',4,4',5-Pentachlorobiphenyl; Polychlorinated dibenzofurans; TCDD; Enzymes; Spleen; Antibody response; polychlorinated biphenyls; Body weight; Dibenzofuran; Lung; Dose-response effects; Dibenzo-p-dioxin; Liver; Cytochrome P450; Dioxin; PCB; Immunosuppression; enzymatic activity; Mice; Dioxins; PCDF; sheep; PCB compounds; body weight; PCDD DO - http://dx.doi.org/10.1016/j.taap.2007.11.018 ER - TY - CPAPER T1 - Asthmatic Human Serum IgE-Reactivity with Mold Extracts T2 - 2008 Annual Meeting of the American Academy of Allergy Asthma and Immunology AN - 40734606; 4763582 JF - 2008 Annual Meeting of the American Academy of Allergy Asthma and Immunology AU - Ward, M D W AU - Chung, Y AU - Svendsen, E AU - Yeatts, K AU - Peden, D AU - Neas, L AU - Devlin, R Y1 - 2008/03/14/ PY - 2008 DA - 2008 Mar 14 KW - Molds KW - Asthma KW - Serum KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40734606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Annual+Meeting+of+the+American+Academy+of+Allergy+Asthma+and+Immunology&rft.atitle=Asthmatic+Human+Serum+IgE-Reactivity+with+Mold+Extracts&rft.au=Ward%2C+M+D+W%3BChung%2C+Y%3BSvendsen%2C+E%3BYeatts%2C+K%3BPeden%2C+D%3BNeas%2C+L%3BDevlin%2C+R&rft.aulast=Ward&rft.aufirst=M+D&rft.date=2008-03-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Meeting+of+the+American+Academy+of+Allergy+Asthma+and+Immunology&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/?mkey=%7B4F6F2478%2DD5DF%2D49CD% 2D8D8E%2DDF42F8952832%7D LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Chlorinated Compounds Case Study: Grants Chlorinated Solvents Plume Site T2 - 18th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AN - 40808638; 4795684 JF - 18th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AU - Appaji, Sai S Y1 - 2008/03/10/ PY - 2008 DA - 2008 Mar 10 KW - Case studies KW - Plumes KW - Grants KW - Solvents KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40808638?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=18th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Chlorinated+Compounds+Case+Study%3A+Grants+Chlorinated+Solvents+Plume+Site&rft.au=Appaji%2C+Sai+S&rft.aulast=Appaji&rft.aufirst=Sai&rft.date=2008-03-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=18th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.aehs.com/conferences/westcoast/pdfs/WC08Prelim.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Recommendations for Improved Characterization of the Groundwater Vapor Intrusion Source Term T2 - 18th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AN - 40808111; 4795734 JF - 18th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AU - Schuver, Henry Y1 - 2008/03/10/ PY - 2008 DA - 2008 Mar 10 KW - Vapors KW - Ground water KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40808111?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=18th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Recommendations+for+Improved+Characterization+of+the+Groundwater+Vapor+Intrusion+Source+Term&rft.au=Schuver%2C+Henry&rft.aulast=Schuver&rft.aufirst=Henry&rft.date=2008-03-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=18th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.aehs.com/conferences/westcoast/pdfs/WC08Prelim.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Risk Management Issues during Indoor Air and Sub-Slab Soil Gas Investigation for Vapor Intrusion T2 - 18th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AN - 40798442; 4795758 JF - 18th Annual AEHS Meeting and West Coast Conference on Soils, Sediments and Water AU - Abbasi, Rafat Y1 - 2008/03/10/ PY - 2008 DA - 2008 Mar 10 KW - Soil KW - Vapors KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40798442?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=18th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Risk+Management+Issues+during+Indoor+Air+and+Sub-Slab+Soil+Gas+Investigation+for+Vapor+Intrusion&rft.au=Abbasi%2C+Rafat&rft.aulast=Abbasi&rft.aufirst=Rafat&rft.date=2008-03-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=18th+Annual+AEHS+Meeting+and+West+Coast+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.aehs.com/conferences/westcoast/pdfs/WC08Prelim.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Distribution of Colored Dissolved Organic Matter (CDOM) and Salinity along the Southern New England Coast from Aircraft Remote Sensing. T2 - 2008 Ocean Sciences Meeting AN - 40820653; 4798938 JF - 2008 Ocean Sciences Meeting AU - Keith, D J AU - Kuhn-Hines, A Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - USA, New England KW - Aircraft KW - Dissolved organic matter KW - Remote sensing KW - Salinity effects KW - Coasts KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40820653?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=The+Distribution+of+Colored+Dissolved+Organic+Matter+%28CDOM%29+and+Salinity+along+the+Southern+New+England+Coast+from+Aircraft+Remote+Sensing.&rft.au=Keith%2C+D+J%3BKuhn-Hines%2C+A&rft.aulast=Keith&rft.aufirst=D&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Multiple Regression Models for Hindcasting and Forecasting Midsummer Hypoxia in the Gulf of Mexico. T2 - 2008 Ocean Sciences Meeting AN - 40811027; 4799404 JF - 2008 Ocean Sciences Meeting AU - Greene, R M AU - Lehrter, J C AU - Hagy, J D Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Mexico Gulf KW - Hypoxia KW - Regression analysis KW - Models KW - Prediction KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40811027?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Multiple+Regression+Models+for+Hindcasting+and+Forecasting+Midsummer+Hypoxia+in+the+Gulf+of+Mexico.&rft.au=Greene%2C+R+M%3BLehrter%2C+J+C%3BHagy%2C+J+D&rft.aulast=Greene&rft.aufirst=R&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differential Growth Rates of Symbiodinium Isolates Exposed to the Combined Effects of Elevated Temperature and Ultraviolet Radiation T2 - 2008 Ocean Sciences Meeting AN - 40810371; 4798634 JF - 2008 Ocean Sciences Meeting AU - Rogers, J E AU - Marcovich, M AU - Cross, R AU - Galleher, S Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - U.V. radiation KW - Temperature effects KW - Growth rate KW - Abiotic factors KW - Symbiodinium KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40810371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Differential+Growth+Rates+of+Symbiodinium+Isolates+Exposed+to+the+Combined+Effects+of+Elevated+Temperature+and+Ultraviolet+Radiation&rft.au=Rogers%2C+J+E%3BMarcovich%2C+M%3BCross%2C+R%3BGalleher%2C+S&rft.aulast=Rogers&rft.aufirst=J&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Application of a Watershed Nitrogen Loading Model to Forty-Nine (49) Medium Sized Southern New England Embayment Type Estuaries T2 - 2008 Ocean Sciences Meeting AN - 40806577; 4797176 JF - 2008 Ocean Sciences Meeting AU - Latimer, J S AU - Mickinney, R AU - Cicchetti, G AU - Charpentier, M Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - USA, New England KW - Watersheds KW - Estuaries KW - Nitrogen KW - Models KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40806577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Application+of+a+Watershed+Nitrogen+Loading+Model+to+Forty-Nine+%2849%29+Medium+Sized+Southern+New+England+Embayment+Type+Estuaries&rft.au=Latimer%2C+J+S%3BMickinney%2C+R%3BCicchetti%2C+G%3BCharpentier%2C+M&rft.aulast=Latimer&rft.aufirst=J&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Quantitative Evaluation of a Multi-Trophic Level Ecosystem Model for Population Dynamics of the Invasive Species Bythotrephes Longimanus in Lake Michigan T2 - 2008 Ocean Sciences Meeting AN - 40806274; 4798261 JF - 2008 Ocean Sciences Meeting AU - Miller, D H AU - Kreis Jr, R G AU - Huang, W AU - Xia, X Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - USA, Michigan L. KW - Invasive species KW - Lakes KW - Population dynamics KW - Introduced species KW - Ecosystem models KW - Bythotrephes longimanus KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40806274?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Quantitative+Evaluation+of+a+Multi-Trophic+Level+Ecosystem+Model+for+Population+Dynamics+of+the+Invasive+Species+Bythotrephes+Longimanus+in+Lake+Michigan&rft.au=Miller%2C+D+H%3BKreis+Jr%2C+R+G%3BHuang%2C+W%3BXia%2C+X&rft.aulast=Miller&rft.aufirst=D&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The use of Dated Sediment Cores to Describe the History of Contaminant Loads to Systems: A Case Study of Mercury Fluxes to Lake Michigan T2 - 2008 Ocean Sciences Meeting AN - 40806193; 4797247 JF - 2008 Ocean Sciences Meeting AU - Rossmann, R Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - USA, Michigan L. KW - Case studies KW - Mercury KW - Historical account KW - Sediment pollution KW - Lake deposits KW - Contaminants KW - Cores KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40806193?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=The+use+of+Dated+Sediment+Cores+to+Describe+the+History+of+Contaminant+Loads+to+Systems%3A+A+Case+Study+of+Mercury+Fluxes+to+Lake+Michigan&rft.au=Rossmann%2C+R&rft.aulast=Rossmann&rft.aufirst=R&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Primary Production, Bacterioplankton Production, and Community Respiration on the Northern Gulf of Mexico Continental Shelf: Linkage to Hypoxia. T2 - 2008 Ocean Sciences Meeting AN - 40805439; 4796639 JF - 2008 Ocean Sciences Meeting AU - Murrell, M C AU - Vickery, S S AU - Stanley, R S AU - Lehrter, J C AU - Kurtz, J C AU - Hagy, J D AU - Schaeffer, B A Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Mexico Gulf KW - Hypoxia KW - Respiration KW - Primary production KW - Bacterioplankton KW - Biological production KW - Nannoplankton KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40805439?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Primary+Production%2C+Bacterioplankton+Production%2C+and+Community+Respiration+on+the+Northern+Gulf+of+Mexico+Continental+Shelf%3A+Linkage+to+Hypoxia.&rft.au=Murrell%2C+M+C%3BVickery%2C+S+S%3BStanley%2C+R+S%3BLehrter%2C+J+C%3BKurtz%2C+J+C%3BHagy%2C+J+D%3BSchaeffer%2C+B+A&rft.aulast=Murrell&rft.aufirst=M&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Can Fast Repetition Rate Fluorometry and Satellite Ocean Color Data be Combined to Examine Gulf of Mexico Hypoxia? T2 - 2008 Ocean Sciences Meeting AN - 40803766; 4798170 JF - 2008 Ocean Sciences Meeting AU - Kurtz, J C AU - Miller, R L Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Mexico Gulf KW - Hypoxia KW - Remote sensing KW - Satellites KW - Oceans KW - Repetition KW - Color KW - Fluorometry KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40803766?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Can+Fast+Repetition+Rate+Fluorometry+and+Satellite+Ocean+Color+Data+be+Combined+to+Examine+Gulf+of+Mexico+Hypoxia%3F&rft.au=Kurtz%2C+J+C%3BMiller%2C+R+L&rft.aulast=Kurtz&rft.aufirst=J&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Coupled Biological-Physical Processes Affecting Hypoxia in the Northern Gulf of Mexico. T2 - 2008 Ocean Sciences Meeting AN - 40803690; 4796641 JF - 2008 Ocean Sciences Meeting AU - Hagy, J D AU - Murrell, M C AU - Lehrter, J C AU - Stanley, R S AU - Schaeffer, B A Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Mexico Gulf KW - Hypoxia KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40803690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Coupled+Biological-Physical+Processes+Affecting+Hypoxia+in+the+Northern+Gulf+of+Mexico.&rft.au=Hagy%2C+J+D%3BMurrell%2C+M+C%3BLehrter%2C+J+C%3BStanley%2C+R+S%3BSchaeffer%2C+B+A&rft.aulast=Hagy&rft.aufirst=J&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Hypoxia on Animal Burrow Construction and Consequent Effects on Sediment Redox Profiles. T2 - 2008 Ocean Sciences Meeting AN - 40803577; 4799398 JF - 2008 Ocean Sciences Meeting AU - Weissberger, E J AU - Coiro, L L AU - Davey, E W Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Hypoxia KW - Sediment pollution KW - Sediment chemistry KW - Burrowing organisms KW - Zoobenthos KW - Redox reactions KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40803577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Effects+of+Hypoxia+on+Animal+Burrow+Construction+and+Consequent+Effects+on+Sediment+Redox+Profiles.&rft.au=Weissberger%2C+E+J%3BCoiro%2C+L+L%3BDavey%2C+E+W&rft.aulast=Weissberger&rft.aufirst=E&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Does Temperature Structure Phytoplankton Community Composition in the Ross Sea, Antarctica? T2 - 2008 Ocean Sciences Meeting AN - 40803372; 4796370 JF - 2008 Ocean Sciences Meeting AU - Shields, A R AU - Peloquin, J A AU - Smith, Jr., W. O. Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Ross Sea KW - Antarctica KW - Community composition KW - Phytoplankton KW - Temperature effects KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40803372?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Does+Temperature+Structure+Phytoplankton+Community+Composition+in+the+Ross+Sea%2C+Antarctica%3F&rft.au=Shields%2C+A+R%3BPeloquin%2C+J+A%3BSmith%2C+Jr.%2C+W.+O.&rft.aulast=Shields&rft.aufirst=A&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Photobiogeochemistry of Sargassum: A Potentially Important Source of Chromophoric Dissolved Organic Matter in the Upper Ocean T2 - 2008 Ocean Sciences Meeting AN - 40802641; 4797702 JF - 2008 Ocean Sciences Meeting AU - Zepp, R G AU - Shank, G C AU - Vahatalo, A AU - Bartels, E AU - Jones, R P Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Upper ocean KW - Dissolved organic matter KW - Sargassum KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40802641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Photobiogeochemistry+of+Sargassum%3A+A+Potentially+Important+Source+of+Chromophoric+Dissolved+Organic+Matter+in+the+Upper+Ocean&rft.au=Zepp%2C+R+G%3BShank%2C+G+C%3BVahatalo%2C+A%3BBartels%2C+E%3BJones%2C+R+P&rft.aulast=Zepp&rft.aufirst=R&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dynamics of Phytoplankton, Detritus, and Colored Dissolved Organic Matter in Hypoxic and Non-Hypoxic Gulf of Mexico Waters. T2 - 2008 Ocean Sciences Meeting AN - 40802555; 4796645 JF - 2008 Ocean Sciences Meeting AU - Schaeffer, B A AU - Hagy, J AU - Kurtz, J AU - Murrell, M AU - Smith, G Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Mexico Gulf KW - Hypoxia KW - Dissolved organic matter KW - Phytoplankton KW - Detritus KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40802555?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Dynamics+of+Phytoplankton%2C+Detritus%2C+and+Colored+Dissolved+Organic+Matter+in+Hypoxic+and+Non-Hypoxic+Gulf+of+Mexico+Waters.&rft.au=Schaeffer%2C+B+A%3BHagy%2C+J%3BKurtz%2C+J%3BMurrell%2C+M%3BSmith%2C+G&rft.aulast=Schaeffer&rft.aufirst=B&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Factors Influencing Nitrogen-Chlorophyll Relationships for Ten Estuaries on the U.S. Atlantic and Gulf of Mexico Coasts T2 - 2008 Ocean Sciences Meeting AN - 40801914; 4798463 JF - 2008 Ocean Sciences Meeting AU - Dettmann, E H Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - USA KW - Mexico Gulf KW - Estuaries KW - Coasts KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40801914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Factors+Influencing+Nitrogen-Chlorophyll+Relationships+for+Ten+Estuaries+on+the+U.S.+Atlantic+and+Gulf+of+Mexico+Coasts&rft.au=Dettmann%2C+E+H&rft.aulast=Dettmann&rft.aufirst=E&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Landscape Indicators of Watershed Impairment - Nutrients. T2 - 2008 Ocean Sciences Meeting AN - 40801577; 4799369 JF - 2008 Ocean Sciences Meeting AU - Russell, M J AU - Weller, D E AU - Jordan, T E Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Nutrients KW - Watersheds KW - Landscape KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40801577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Landscape+Indicators+of+Watershed+Impairment+-+Nutrients.&rft.au=Russell%2C+M+J%3BWeller%2C+D+E%3BJordan%2C+T+E&rft.aulast=Russell&rft.aufirst=M&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Estimating Response Times of Oceans to Mercury Emission Reductions and Implications for Exposure from Marine Fish. T2 - 2008 Ocean Sciences Meeting AN - 40801246; 4799295 JF - 2008 Ocean Sciences Meeting AU - Sunderland, E M AU - Mason, R P AU - Selin, N E AU - Strode, S AU - Krabbenhoft, D P Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Mercury KW - Oceans KW - Emission control KW - Marine fishes KW - Pollution indicators KW - Response time KW - Toxicity testing KW - Marine fish KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40801246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Estimating+Response+Times+of+Oceans+to+Mercury+Emission+Reductions+and+Implications+for+Exposure+from+Marine+Fish.&rft.au=Sunderland%2C+E+M%3BMason%2C+R+P%3BSelin%2C+N+E%3BStrode%2C+S%3BKrabbenhoft%2C+D+P&rft.aulast=Sunderland&rft.aufirst=E&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Variability of the Diffuse Downwelling Irradiance in Gulf of Mexico Hypoxic and Non-Hypoxic Waters. T2 - 2008 Ocean Sciences Meeting AN - 40800339; 4796644 JF - 2008 Ocean Sciences Meeting AU - Rivord, J AU - Schaeffer, B A Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - Mexico Gulf KW - Hypoxia KW - Irradiance KW - Downwelling KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40800339?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Variability+of+the+Diffuse+Downwelling+Irradiance+in+Gulf+of+Mexico+Hypoxic+and+Non-Hypoxic+Waters.&rft.au=Rivord%2C+J%3BSchaeffer%2C+B+A&rft.aulast=Rivord&rft.aufirst=J&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sediment Metabolism on the Louisiana Continental Shelf. T2 - 2008 Ocean Sciences Meeting AN - 40799236; 4796642 JF - 2008 Ocean Sciences Meeting AU - Lehrter, J AU - Devereux, R AU - Eldridge, P AU - Beddick, D AU - Fry, B Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - USA, Louisiana KW - Metabolism KW - Sediment pollution KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40799236?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Sediment+Metabolism+on+the+Louisiana+Continental+Shelf.&rft.au=Lehrter%2C+J%3BDevereux%2C+R%3BEldridge%2C+P%3BBeddick%2C+D%3BFry%2C+B&rft.aulast=Lehrter&rft.aufirst=J&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Resuspended Sediments can Contribute to the Establishment and Maintenance of Hypoxia on the Louisiana Continental Shelf. T2 - 2008 Ocean Sciences Meeting AN - 40798681; 4796646 JF - 2008 Ocean Sciences Meeting AU - Beddick, Jr., D. L. AU - Devereux, R AU - Eldridge, P M AU - Lehrter, J C AU - Yates, D F Y1 - 2008/03/02/ PY - 2008 DA - 2008 Mar 02 KW - USA, Louisiana KW - Hypoxia KW - Resuspended sediments KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40798681?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Ocean+Sciences+Meeting&rft.atitle=Resuspended+Sediments+can+Contribute+to+the+Establishment+and+Maintenance+of+Hypoxia+on+the+Louisiana+Continental+Shelf.&rft.au=Beddick%2C+Jr.%2C+D.+L.%3BDevereux%2C+R%3BEldridge%2C+P+M%3BLehrter%2C+J+C%3BYates%2C+D+F&rft.aulast=Beddick&rft.aufirst=Jr.&rft.date=2008-03-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Ocean+Sciences+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aslo.org/orlando2008/sessionlist.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species. AN - 71644835; 17990945 AB - The research presented here is part of a larger study of the molecular mode of action of endocrine-disrupting chemicals targeting the hypothalamic-pituitary-gonadal axis in zebrafish (Danio rerio). It addresses several issues critical to microarray application in aquatic ecotoxicology: experimental design, microarray scanning, gene expression intensity distribution, and the effect of experimental parameters on the zebrafish transcriptome. Expression profiles from various tissues of individual zebrafish exposed to 17alpha-ethinylestradiol (30 ng/L), fadrozole (25 micro.g/L), or 17beta-trenbolone (3.0 microg/L) for 48 or 96 h were examined with the Agilent Oligo Microarray (G2518A). As a flexible and efficient alternative to the designs commonly used in microarray studies, an unbalanced incomplete block design was found to be well suited for this work, as evidenced by high data reproducibility, low microarray-to-microarray variability, and little gene-specific dye bias. Random scanner noise had little effect on data reproducibility. A low-level, slightly variable Cyanine 3 (Cy3) contaminant was revealed by hyperspectral imaging, suggesting fluorescence contamination as a potential contributor to the large variance associated with weakly expressed genes. Expression intensities of zebrafish genes were skewed toward the lower end of their distribution range, and more weakly expressed genes tended to have larger variances. Tissue type, followed in descending order by gender, chemical treatment, and exposure duration, had the greatest effect on the overall gene expression profiles, a finding potentially critical to experimental design optimization. Overall, congruence was excellent between quantitative polymerase chain reaction results and microarray profiles of 13 genes examined across a subset of 20 pairs of ovarian samples. These findings will help to improve applications of microarrays in future ecotoxicological studies. JF - Environmental toxicology and chemistry AU - Wang, Rong-Lin AU - Biales, Adam AU - Bencic, David AU - Lattier, David AU - Kostich, Mitch AU - Villeneuve, Dan AU - Ankley, Gerald T AU - Lazorchak, Jim AU - Toth, Greg AD - Ecological Exposure Research Division, National Exposure Research Laboratory, US Environmental Protection Agency, Cincinnati, Ohio 45268, USA. wang.rong-lin@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 652 EP - 663 VL - 27 IS - 3 SN - 0730-7268, 0730-7268 KW - Water Pollutants, Chemical KW - 0 KW - Zebrafish Proteins KW - Ethinyl Estradiol KW - 423D2T571U KW - Fadrozole KW - H3988M64PU KW - Trenbolone Acetate KW - RUD5Y4SV0S KW - Index Medicus KW - Trenbolone Acetate -- toxicity KW - Animals KW - Testis -- metabolism KW - Brain -- drug effects KW - Ovary -- drug effects KW - Brain -- metabolism KW - Ethinyl Estradiol -- toxicity KW - Zebrafish Proteins -- metabolism KW - Ovary -- metabolism KW - Testis -- drug effects KW - Fadrozole -- toxicity KW - Zebrafish Proteins -- genetics KW - Female KW - Male KW - Oligonucleotide Array Sequence Analysis KW - Zebrafish -- metabolism KW - Water Pollutants, Chemical -- toxicity KW - Transcription, Genetic KW - Zebrafish -- genetics KW - Gene Expression Profiling -- methods KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71644835?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=DNA+microarray+application+in+ecotoxicology%3A+experimental+design%2C+microarray+scanning%2C+and+factors+affecting+transcriptional+profiles+in+a+small+fish+species.&rft.au=Wang%2C+Rong-Lin%3BBiales%2C+Adam%3BBencic%2C+David%3BLattier%2C+David%3BKostich%2C+Mitch%3BVilleneuve%2C+Dan%3BAnkley%2C+Gerald+T%3BLazorchak%2C+Jim%3BToth%2C+Greg&rft.aulast=Wang&rft.aufirst=Rong-Lin&rft.date=2008-03-01&rft.volume=27&rft.issue=3&rft.spage=652&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-28 N1 - Date created - 2008-06-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Temporal and spatial variation in solar radiation and photoenhanced toxicity risks of spilled oil in Prince William Sound, Alaska, USA. AN - 71619172; 17983275 AB - Solar irradiance (W/m2) and downwelling diffuse attenuation coefficients (Kd; 1/m) were determined in several locations in Prince William Sound (AK, USA) between April 2003 and December 2005 to assess temporal and spatial variation in solar radiation and the risks of photo-enhanced toxicity from spilled oil. Weekly irradiance measurements of surface visible light, ultraviolet B (UVB), and ultraviolet A (UVA) radiation in Valdez (AK, USA) followed expected trends of maximum solar irradiance at each summer solstice and minimum values at each winter solstice. Variation from weekly maximum expected surface irradiances was attributed to large variations in environmental conditions over the 142-week monitoring period. Season and proximity to glacial meltwater were significant determinants of Kd, with 1% attenuation depths ranging from 0.4 to 15 m (UVB and UVA) and from 0.5 to 28 m (visible light). The probability of photo-enhanced toxicity risks estimated from UVA dosimetry decreased with increasing water depth, with higher risks during spring and summer and lower risks during fall and winter. These results demonstrate substantial temporal and spatial variation in solar radiation in Prince William Sound and the potential for significant season- and location-specific photo-enhanced toxicity risks from spilled oil. JF - Environmental toxicology and chemistry AU - Barron, Mace G AU - Vivian, Deborah AU - Yee, Susan H AU - Diamond, Steve A AD - Gulf Ecology Division, US Environmental Protection Agency, Gulf Breeze, Florida 32561, USA. barron.mace@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 727 EP - 736 VL - 27 IS - 3 SN - 0730-7268, 0730-7268 KW - Fuel Oils KW - 0 KW - Water Pollutants, Chemical KW - Index Medicus KW - Environmental Monitoring KW - Ecosystem KW - Oceans and Seas KW - Ultraviolet Rays KW - Seasons KW - Alaska KW - Time Factors KW - Arctic Regions KW - Water Pollutants, Chemical -- toxicity KW - Sunlight KW - Fuel Oils -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71619172?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Temporal+and+spatial+variation+in+solar+radiation+and+photoenhanced+toxicity+risks+of+spilled+oil+in+Prince+William+Sound%2C+Alaska%2C+USA.&rft.au=Barron%2C+Mace+G%3BVivian%2C+Deborah%3BYee%2C+Susan+H%3BDiamond%2C+Steve+A&rft.aulast=Barron&rft.aufirst=Mace&rft.date=2008-03-01&rft.volume=27&rft.issue=3&rft.spage=727&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-28 N1 - Date created - 2008-06-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Toxicity equivalency values for polychlorinated biphenyl mixtures. AN - 71616526; 17967071 AB - For aquatic, avian, and mammalian species, dioxin equivalency values (TEQs) were computed for Aroclor, Clophen, Kanechlor, Chlorofen, Sovol, Delor, Phenoclor, and Chinese polychlorinated biphenyl (PCB) mixtures by using World Health Organization toxicity equivalency factors (TEFs) and compound-specific compositional data for PCBs, polychlorinated dibenzo-p-dioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) for the individual mixtures. The TEQs were similar across the different PCB product lines for mixtures of similar chlorine content. Depending on the PCB mixture, the polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) in the mixture contributed anywhere from 0 to 96% of the total TEQs, and the impact of PCDD/Fs was greatest for the fish TEQs. In comparison to the dioxin-like PCBs, few measurements have been performed for PCDD/Fs in the commercial PCB products. JF - Environmental toxicology and chemistry AU - Burkhard, Lawrence P AU - Lukasewycz, Marta T AD - Mid-Continent Ecology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Duluth, Minnesota 55804, USA. burkhard.lawrence@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 529 EP - 534 VL - 27 IS - 3 SN - 0730-7268, 0730-7268 KW - Complex Mixtures KW - 0 KW - Environmental Pollutants KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - Environmental Monitoring KW - Animals KW - World Health Organization KW - Mammals KW - Medical Informatics KW - Fishes KW - Birds KW - Environmental Pollutants -- toxicity KW - Polychlorinated Biphenyls -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71616526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Toxicity+equivalency+values+for+polychlorinated+biphenyl+mixtures.&rft.au=Burkhard%2C+Lawrence+P%3BLukasewycz%2C+Marta+T&rft.aulast=Burkhard&rft.aufirst=Lawrence&rft.date=2008-03-01&rft.volume=27&rft.issue=3&rft.spage=529&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-28 N1 - Date created - 2008-06-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - DNA microarray-based ecotoxicological biomarker discovery in a small fish model species. AN - 71615251; 17990946 AB - As potential biomarkers, gene classifiers are gene expression signatures or patterns capable of distinguishing biological samples belonging to different classes or conditions. This is the second of two papers on profiling gene expression in zebrafish (Danio rerio) treated with endocrine-disrupting chemicals of different modes of action, with a focus on comparative analysis of microarray data for gene classifier discovery. Various combinations of gene feature selection/class prediction algorithms were evaluated, with the use of microarray data organized by a chemical stressor or tissue type, for their accuracy in determining the class memberships of independent test samples. Two-way clustering of gene classifiers and treatment conditions offered another alternative to assess the performance of these potential biomarkers. Both gene feature selection methods and class prediction algorithms were shown to be important in identifying successful gene classifiers. The genetic algorithm and support vector machine yielded classifiers with the best prediction accuracy, regardless of sample size, nature of class prediction, and data complexity. A chemical stressor significantly altering the expression of a greater number of genes tended to generate gene classifiers with better performance. All combinations of gene feature selection/class prediction algorithms performed similarly well with data of high signal to noise ratio. Gene classifier discovery and application on the basis of individual sampling and sample data pooling, respectively, were found to enhance class predictions. Gene expression profiles of the top gene classifiers, identified from both microarray and quantitative polymerase chain reaction assays, displayed greater similarity between fadrozole and 17beta-trenbolone than either one to 17alpha-ethinylestradiol. These gene classifiers could serve as potential biomarkers of exposure to specific classes of endocrine disruptors. JF - Environmental toxicology and chemistry AU - Wang, Rong-Lin AU - Bencic, David AU - Biales, Adam AU - Lattier, David AU - Kostich, Mitch AU - Villeneuve, Dan AU - Ankley, Gerald T AU - Lazorchak, Jim AU - Toth, Greg AD - Ecological Exposure Research Division, National Exposure Research Lab, US Environmental Protection Agency, Cincinnati, Ohio 45268, USA. wang.rong-lin@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 664 EP - 675 VL - 27 IS - 3 SN - 0730-7268, 0730-7268 KW - Biomarkers KW - 0 KW - Water Pollutants, Chemical KW - Zebrafish Proteins KW - Ethinyl Estradiol KW - 423D2T571U KW - Fadrozole KW - H3988M64PU KW - Trenbolone Acetate KW - RUD5Y4SV0S KW - Index Medicus KW - Trenbolone Acetate -- toxicity KW - Animals KW - Testis -- metabolism KW - Brain -- drug effects KW - Ovary -- drug effects KW - Brain -- metabolism KW - Ethinyl Estradiol -- toxicity KW - Zebrafish Proteins -- metabolism KW - Environmental Monitoring KW - Gene Expression Profiling KW - Ovary -- metabolism KW - Testis -- drug effects KW - Fadrozole -- toxicity KW - Gene Expression Regulation KW - Zebrafish Proteins -- genetics KW - Female KW - Male KW - Oligonucleotide Array Sequence Analysis KW - Zebrafish -- metabolism KW - Water Pollutants, Chemical -- toxicity KW - Biomarkers -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71615251?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=DNA+microarray-based+ecotoxicological+biomarker+discovery+in+a+small+fish+model+species.&rft.au=Wang%2C+Rong-Lin%3BBencic%2C+David%3BBiales%2C+Adam%3BLattier%2C+David%3BKostich%2C+Mitch%3BVilleneuve%2C+Dan%3BAnkley%2C+Gerald+T%3BLazorchak%2C+Jim%3BToth%2C+Greg&rft.aulast=Wang&rft.aufirst=Rong-Lin&rft.date=2008-03-01&rft.volume=27&rft.issue=3&rft.spage=664&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-28 N1 - Date created - 2008-06-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Tobacco and pregnancy: overview of exposures and effects. AN - 70473924; 18383133 AB - This opening article will review the epidemiology of the effects of cigarette smoking and other forms of tobacco exposure on human development. Sources of exposure described include cigarettes and other forms of smoked tobacco, secondhand (environmental) tobacco smoke, several forms of smokeless tobacco, and nicotine from nicotine replacement therapy. Exposure is immense and worldwide, most of it due to smoking, but in some parts of the world and in some populations, smoking is exceeded by smokeless tobacco use. Nicotine and carbon monoxide exposure are of large concern, but cigarette smoke contains over 4000 chemical constituents and additives including known carcinogens, toxic heavy metals, and many chemicals untested for developmental toxicity. The impact of tobacco on human development will be reviewed. Fertility, conception, survival of the conceptus, most phases and aspects of development studied to date, as well as postnatal survival and health are adversely impacted by maternal tobacco use or exposure. Effects in surviving offspring are probably life-long, and are still being elucidated. It is hoped that this review and those to follow in this issue will serve to keep a focus on the critical and continuing problem of tobacco use impacting human development. JF - Birth defects research. Part C, Embryo today : reviews AU - Rogers, John M AD - Developmental Biology Branch, Reproductive Toxicology Division, United States Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. rogers.john@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 1 EP - 15 VL - 84 IS - 1 KW - Tobacco Smoke Pollution KW - 0 KW - Index Medicus KW - Humans KW - Fetal Development KW - Female KW - Pregnancy KW - Pregnancy Complications KW - Tobacco Smoke Pollution -- adverse effects KW - Smoking -- adverse effects KW - Maternal Exposure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70473924?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+C%2C+Embryo+today+%3A+reviews&rft.atitle=Tobacco+and+pregnancy%3A+overview+of+exposures+and+effects.&rft.au=Rogers%2C+John+M&rft.aulast=Rogers&rft.aufirst=John&rft.date=2008-03-01&rft.volume=84&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+C%2C+Embryo+today+%3A+reviews&rft.issn=1542-9768&rft_id=info:doi/10.1002%2Fbdrc.20119 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-29 N1 - Date created - 2008-04-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/bdrc.20119 ER - TY - JOUR T1 - Resolving local-scale emissions for modeling air quality near roadways. AN - 70451377; 18376647 AB - A large body of literature published in recent years suggests increased health risk due to exposure of people to air pollution in close proximity to roadways. As a result, there is a need to more accurately represent the spatial concentration gradients near roadways to develop mitigation strategies. In this paper, we present a practical, readily adaptable methodology, using a "bottom-up" approach to develop a detailed highway vehicle emission inventory that includes emissions for individual road links. This methodology also takes advantage of geographic information system (GIS) software to improve the spatial accuracy of the activity information obtained from a Travel Demand Model. In addition, we present an air quality modeling application of this methodology in New Haven, CT. This application uses a hybrid modeling approach, in which a regional grid-based model is used to characterize average local ambient concentrations, and a Gaussian dispersion model is used to provide texture within the modeling domain because of spatial gradients associated with highway vehicle emissions and other local sources. Modeling results show substantial heterogeneity of pollutant concentrations within the modeling domain and strong spatial gradients associated with roadways, particularly for pollutants dominated by direct emissions. JF - Journal of the Air & Waste Management Association (1995) AU - Cook, Rich AU - Isakov, Vlad AU - Touma, Jawad S AU - Benjey, William AU - Thurman, James AU - Kinnee, Ellen AU - Ensley, Darrell AD - Office of Transportation and Air Quality, U.S. Environmental Protection Agency, Ann Arbor, MI, USA. Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 451 EP - 461 VL - 58 IS - 3 SN - 1096-2247, 1096-2247 KW - Air Pollutants, Occupational KW - 0 KW - Vehicle Emissions KW - Index Medicus KW - Environmental Monitoring KW - Environmental Health KW - Circadian Rhythm KW - Data Interpretation, Statistical KW - Models, Statistical KW - Connecticut KW - Air Pollution -- analysis KW - Air Pollutants, Occupational -- analysis KW - Vehicle Emissions -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70451377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Resolving+local-scale+emissions+for+modeling+air+quality+near+roadways.&rft.au=Cook%2C+Rich%3BIsakov%2C+Vlad%3BTouma%2C+Jawad+S%3BBenjey%2C+William%3BThurman%2C+James%3BKinnee%2C+Ellen%3BEnsley%2C+Darrell&rft.aulast=Cook&rft.aufirst=Rich&rft.date=2008-03-01&rft.volume=58&rft.issue=3&rft.spage=451&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-23 N1 - Date created - 2008-04-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Cardiopulmonary responses of intratracheally instilled tire particles and constituent metal components. AN - 70432645; 18368618 AB - Tire and brake wear particles contain transition metals, and contribute to near-road PM. We hypothesized that acute cardiopulmonary injury from respirable tire particles (TP) will depend on the amount of soluble metals. Respirable fractions of two types of TP (TP1 and TP2) were analyzed for water and acid-leachable metals using ICP-AES. Both TP types contained a variety of transition metals, including zinc (Zn), copper (Cu), aluminum, and iron. Zn and Cu were detected at high levels in water-soluble fractions (TP2 > TP1). Male Wistar Kyoto rats (12-14 wk) were intratracheally instilled, in the first study, with saline, TP1 or TP2 (5 mg/kg), and in the second study, with soluble Zn, Cu (0.5 micromol/kg), or both. Pulmonary toxicity and cardiac mitochondrial enzymes were analyzed 1 d, 1 wk, or 4 wk later for TP and 4 or 24 h later for metals. Increases in lavage fluid markers of inflammation and injury were observed at d 1 (TP2 > TP1), but these changes reversed by wk 1. No effects on cardiac enzymes were noted with either TP. Exposure of rats to soluble Zn and Cu caused marked pulmonary inflammation and injury but temporal differences were apparent (Cu effects peaked at 4 h and Zn at 24 h). Instillation of Zn, Cu, and Zn + Cu decreased the activity of cardiac aconitase, isocitrate dehydrogenase, succinate dehydrogenase, cytochrome-c-oxidase and superoxide dismutase suggesting mitochondrial oxidative stress. The observed acute pulmonary toxicity of TP could be due to the presence of water soluble Zn and Cu. At high concentrations these metals may induce cardiac oxidative stress. JF - Inhalation toxicology AU - Gottipolu, Reddy R AU - Landa, Edward R AU - Schladweiler, Mette C AU - McGee, John K AU - Ledbetter, Allen D AU - Richards, Judy H AU - Wallenborn, Grace J AU - Kodavanti, Urmila P AD - National Research Council, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA. Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 473 EP - 484 VL - 20 IS - 5 KW - Metals KW - 0 KW - Particulate Matter KW - Index Medicus KW - Rats KW - Animals KW - Rats, Inbred WKY KW - Particle Size KW - Injections, Spinal KW - Bronchoalveolar Lavage Fluid -- cytology KW - Male KW - Particulate Matter -- toxicity KW - Pneumonia -- chemically induced KW - Metals -- administration & dosage KW - Particulate Matter -- administration & dosage KW - Mitochondria, Heart -- drug effects KW - Mitochondria, Heart -- metabolism KW - Mitochondria, Heart -- pathology KW - Pneumonia -- pathology KW - Pneumonia -- metabolism KW - Metals -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70432645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inhalation+toxicology&rft.atitle=Cardiopulmonary+responses+of+intratracheally+instilled+tire+particles+and+constituent+metal+components.&rft.au=Gottipolu%2C+Reddy+R%3BLanda%2C+Edward+R%3BSchladweiler%2C+Mette+C%3BMcGee%2C+John+K%3BLedbetter%2C+Allen+D%3BRichards%2C+Judy+H%3BWallenborn%2C+Grace+J%3BKodavanti%2C+Urmila+P&rft.aulast=Gottipolu&rft.aufirst=Reddy&rft.date=2008-03-01&rft.volume=20&rft.issue=5&rft.spage=473&rft.isbn=&rft.btitle=&rft.title=Inhalation+toxicology&rft.issn=1091-7691&rft_id=info:doi/10.1080%2F08958370701858427 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-11 N1 - Date created - 2008-03-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/08958370701858427 ER - TY - JOUR T1 - U.S. EPA's Indoor Air Quality programs and CARE. AN - 70405482; 18348394 JF - Journal of environmental health AU - O'Connor, Dennis AD - Office of Radiation and Indoor Air, U.S. Environmental Protection Agency, USA. Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 60 EP - 61 VL - 70 IS - 7 SN - 0022-0892, 0022-0892 KW - Index Medicus KW - United States KW - Asthma -- etiology KW - United States Environmental Protection Agency KW - Humans KW - Government Programs KW - Community Participation KW - Asthma -- prevention & control KW - Community-Institutional Relations KW - Air Pollution, Indoor -- adverse effects KW - Air Pollution, Indoor -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70405482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+health&rft.atitle=U.S.+EPA%27s+Indoor+Air+Quality+programs+and+CARE.&rft.au=O%27Connor%2C+Dennis&rft.aulast=O%27Connor&rft.aufirst=Dennis&rft.date=2008-03-01&rft.volume=70&rft.issue=7&rft.spage=60&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+health&rft.issn=00220892&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-08 N1 - Date created - 2008-03-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Microarray analysis of toxicogenomic effects of triclosan on Staphylococcus aureus. AN - 70381157; 18210102 AB - For the first time, a genome-wide transcriptional analysis was performed to elucidate the cellular response of Staphylococcus aureus to triclosan. Our results indicate that the effects of triclosan are widespread on metabolism, affecting many vital cellular processes. Triclosan downregulated the transcription of genes involved in virulence factor and energy metabolism such as amino acid, carbohydrate, lipid transport, and metabolism, while multidrug resistance genes, coenzyme transport, and metabolism and transcription genes were upregulated. Furthermore, triclosan downregulated the transcription of genes encoding major lipid metabolism enzymes such as 3-hydroxyacyl-CoA dehydrogenase, acetyl-CoA acetyltransferase, acetyl-CoA synthetase, and acetyl-CoA carboxylase, which all play essential roles in S. aureus lipid metabolism. It is interesting to note that the expression of the enoyl-ACP reductase gene, fabI, was not changed after exposure of S. aureus with 0.05 microM triclosan at 10 and 60 min in our study. This work also implies that triclosan may kill S. aureus by interfering with its ability to form cell membranes. Another important implication of our result is that S. aureus may generate resistance factors under triclosan stress. JF - Applied microbiology and biotechnology AU - Jang, Hyeung-Jin AU - Chang, Matthew Wook AU - Toghrol, Freshteh AU - Bentley, William E AD - Center for Biosystems Research, University of Maryland Biotechnology Institute, College Park, MD 20742, USA. jang.hyeungjin@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 695 EP - 707 VL - 78 IS - 4 SN - 0175-7598, 0175-7598 KW - Anti-Bacterial Agents KW - 0 KW - Bacterial Proteins KW - Triclosan KW - 4NM5039Y5X KW - Index Medicus KW - Gene Expression Profiling KW - Bacterial Proteins -- genetics KW - Transcription, Genetic -- drug effects KW - Bacterial Proteins -- metabolism KW - Molecular Sequence Data KW - Gene Expression Regulation, Bacterial -- drug effects KW - Anti-Bacterial Agents -- pharmacology KW - Reverse Transcriptase Polymerase Chain Reaction KW - Genome, Bacterial -- drug effects KW - Triclosan -- pharmacology KW - Staphylococcus aureus -- genetics KW - Staphylococcus aureus -- growth & development KW - Microarray Analysis KW - Staphylococcus aureus -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70381157?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+microbiology+and+biotechnology&rft.atitle=Microarray+analysis+of+toxicogenomic+effects+of+triclosan+on+Staphylococcus+aureus.&rft.au=Jang%2C+Hyeung-Jin%3BChang%2C+Matthew+Wook%3BToghrol%2C+Freshteh%3BBentley%2C+William+E&rft.aulast=Jang&rft.aufirst=Hyeung-Jin&rft.date=2008-03-01&rft.volume=78&rft.issue=4&rft.spage=695&rft.isbn=&rft.btitle=&rft.title=Applied+microbiology+and+biotechnology&rft.issn=01757598&rft_id=info:doi/10.1007%2Fs00253-008-1349-x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-17 N1 - Date created - 2008-03-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s00253-008-1349-x ER - TY - JOUR T1 - Complete inhibition of spontaneous activity in neuronal networks in vitro by deltamethrin and permethrin. AN - 70353610; 18304643 AB - Types I and II pyrethroid insecticides cause temporally distinct decreases in voltage-gated sodium channel (VGSC) inactivation rates that are proposed to underlie their characteristic differences in toxicity signs. How alterations in VGSC channel function give rise to the characteristic differences in signs of pyrethroid intoxication is not completely understood, particularly those changes that occur in functional networks of interconnected neurons. To characterize better pyrethroid actions at the network level, effects of the Type I pyrethroid permethrin (PM) and the Type II pyrethroid deltamethrin (DM) on spontaneous glutamate network-dependent spikes and bursts were investigated in primary cultures of frontal cortex or spinal cord neurons grown on microelectrode arrays (MEAs). Fast GABAergic transmission was blocked by BIC, and concentration-dependent effects of DM (1nM to 5microM) and PM (10nM to 50microM) were examined. Both compounds caused concentration-dependent reductions in the network spike and burst rates. DM was more potent than PM, with IC(50) values of approximately 0.13 and approximately 4microM for inhibition of spike rate in cortical and spinal cord neurons, respectively. Both compounds decreased the percentage of spikes that occurred within a burst and increased the interspike interval within bursts. Onset of effects was rapid, but recovery from total activity loss was not readily achievable. Individual neurons responded heterogeneously; activity of most declined monophasically, but activity in others exhibited biphasic responses with increases followed by decreases in activity. In spinal cord, DM caused a greater number of biphasic responses (29%) than PM (10%). These results demonstrate that both DM and PM inhibit activity of glutamatergic networks, but with different potencies. JF - Neurotoxicology AU - Shafer, T J AU - Rijal, S O AU - Gross, G W AD - Neurotoxicology Division, MD-B105-05, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. shafer.tim@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 203 EP - 212 VL - 29 IS - 2 SN - 0161-813X, 0161-813X KW - Insecticides KW - 0 KW - Nitriles KW - Pyrethrins KW - decamethrin KW - 2JTS8R821G KW - Glutamic Acid KW - 3KX376GY7L KW - Permethrin KW - 509F88P9SZ KW - Index Medicus KW - Animals KW - Mice, Inbred ICR KW - Glutamic Acid -- metabolism KW - Excitatory Postsynaptic Potentials -- drug effects KW - Dose-Response Relationship, Drug KW - Cells, Cultured KW - Microarray Analysis KW - Mice KW - Time Factors KW - Microelectrodes KW - Insecticides -- toxicity KW - Spinal Nerves -- metabolism KW - Cerebral Cortex -- drug effects KW - Neurons -- metabolism KW - Spinal Nerves -- drug effects KW - Cerebral Cortex -- metabolism KW - Pyrethrins -- toxicity KW - Nerve Net -- embryology KW - Neurons -- drug effects KW - Neural Inhibition KW - Permethrin -- toxicity KW - Spinal Nerves -- embryology KW - Cerebral Cortex -- embryology KW - Nerve Net -- drug effects KW - Nerve Net -- metabolism KW - Nitriles -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70353610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Complete+inhibition+of+spontaneous+activity+in+neuronal+networks+in+vitro+by+deltamethrin+and+permethrin.&rft.au=Shafer%2C+T+J%3BRijal%2C+S+O%3BGross%2C+G+W&rft.aulast=Shafer&rft.aufirst=T&rft.date=2008-03-01&rft.volume=29&rft.issue=2&rft.spage=203&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/10.1016%2Fj.neuro.2008.01.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-05 N1 - Date created - 2008-03-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.neuro.2008.01.002 ER - TY - JOUR T1 - Comparison of arsenic content in pelletized poultry house waste and biosolids fertilizer. AN - 70338523; 18023841 AB - Managers of human biosolids have been incorporating the practice of waste pelletization for use as fertilizer since the mid 1920s, and waste pelletization has recently been embraced by some poultry producers as a way to move nutrients away from saturated agricultural land. However, the presence of arsenic in pelletized poultry house waste (PPHW) resulting from the use of organoarsenical antimicrobial drugs in poultry production raises concerns regarding additional incremental population exposures. Arsenic concentrations were determined in PPHW and pelletized biosolids fertilizer (PBF) samples. Pellets were processed using strong acid microwave digestion and analyzed by graphite furnace atomic absorption spectroscopy. The mean arsenic concentration in PPHW (20.1 ppm) fell within the lower part of the range of previously report arsenic concentrations in unpelletized poultry house waste. Arsenic concentrations in PBF, the source of which is less clear than for PPHW, were approximately a factor of 5 times lower than those in PPHW, with a mean concentration of 4.1 ppm. The pelletization and sale of these biological waste fertilizers present new pathways of exposure to arsenic in consumer populations who would otherwise not come into contact with these wastes. Arsenic exposures in humans resulting from use of these fertilizer pellets should be quantified to avoid potential unintended negative consequences of managing wastes through pelletization. JF - Chemosphere AU - Nachman, Keeve E AU - Mihalic, Jana N AU - Burke, Thomas A AU - Geyh, Alison S AD - National Center for Environmental Economics, Office of Policy, Economics and Innovation, United States Environmental Protection Agency, 1200 Pennsylvania Avenue, N.W., EPA West 4339-M, MC 1809T, Washington, DC 20460, USA. nachman.keeve@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 500 EP - 506 VL - 71 IS - 3 SN - 0045-6535, 0045-6535 KW - Fertilizers KW - 0 KW - Manure KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Environmental Monitoring KW - Animals KW - Poultry KW - Humans KW - Manure -- analysis KW - Arsenic -- analysis KW - Waste Disposal, Fluid KW - Fertilizers -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70338523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Comparison+of+arsenic+content+in+pelletized+poultry+house+waste+and+biosolids+fertilizer.&rft.au=Nachman%2C+Keeve+E%3BMihalic%2C+Jana+N%3BBurke%2C+Thomas+A%3BGeyh%2C+Alison+S&rft.aulast=Nachman&rft.aufirst=Keeve&rft.date=2008-03-01&rft.volume=71&rft.issue=3&rft.spage=500&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-10 N1 - Date created - 2008-02-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Arsenic speciation in marine fish and shellfish from American Samoa. AN - 70338344; 18023847 AB - We speciated arsenic compounds in marine fish and shellfish from two islands of the United States Territory of American Samoa in the South Pacific, and found that inorganic arsenic occurred as a minor fraction. The proportion of inorganic arsenic was generally far below the levels of prevailing assumptions typically used in human health risk assessments when only total arsenic is analysed. Fish and shellfish were collected from Tutuila and Ofu between May 2001 and March 2002 (n=383 individual specimens, with 117 composites); sites were selected based on habitat type and were representative of those frequented by local fishers. These islands have moderately developed reef fish fisheries among artisanal fishers, are far removed from any industrial or mining sources of arsenic, and presented an opportunity to study arsenic variations in marine biota from un-impacted environments. Target species were from various trophic levels and are among those frequently harvested for human consumption. We found evidence that arsenic concentrated in some marine species, but did not tend to follow classic trophic patterns for biomagnification or bioaccumulation. For the majority of samples, inorganic arsenic was less than 0.5% of total arsenic, with only a few samples in the range of 1-5%, the latter being mollusks which are recognized to have unusually high arsenic levels in general. This work supports the importance of speciation analysis for arsenic, because of the ubiquitous occurrence of arsenic in the environment, and its variable toxicity depending on chemical form. JF - Chemosphere AU - Peshut, Peter J AU - Morrison, R John AU - Brooks, Barbara A AD - American Samoa Environmental Protection Agency, P.O. Box PPA, Utulei Office Building, Pago Pago, AS 96799, USA. pjp617@uow.edu.au Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 484 EP - 492 VL - 71 IS - 3 SN - 0045-6535, 0045-6535 KW - Water Pollutants, Chemical KW - 0 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Environmental Monitoring KW - Animals KW - American Samoa KW - Arsenic -- metabolism KW - Crustacea -- metabolism KW - Bivalvia -- metabolism KW - Seafood -- analysis KW - Fishes -- metabolism KW - Water Pollutants, Chemical -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70338344?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Arsenic+speciation+in+marine+fish+and+shellfish+from+American+Samoa.&rft.au=Peshut%2C+Peter+J%3BMorrison%2C+R+John%3BBrooks%2C+Barbara+A&rft.aulast=Peshut&rft.aufirst=Peter&rft.date=2008-03-01&rft.volume=71&rft.issue=3&rft.spage=484&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-10 N1 - Date created - 2008-02-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The role of protein binding of trivalent arsenicals in arsenic carcinogenesis and toxicity. AN - 70329017; 18164070 AB - Three of the most plausible biological theories of arsenic carcinogenesis are protein binding, oxidative stress and altered DNA methylation. This review presents the role of trivalent arsenicals binding to proteins in arsenic carcinogenesis. Using vacuum filtration based receptor dissociation binding techniques, the lifetimes of unidentate (<1s), bidentate (1-2min) and tridentate (1-2h) arsenite containing peptide binding complexes were estimated. According to our experimental data some of the protein targets to which arsenite may bind in vivo include tubulin, poly(ADP-ribose)polymerase (PARP-1), thioredoxin reductase, estrogen receptor-alpha, arsenic(+3)methyltransferase and Keap-1. Arsenite binding to tubulin can lead to several of the genetic effects observed after arsenic exposures (aneuploidy, polyploidy and mitotic arrests). Among many other possible arsenite binding sites are rat hemoglobin, the DNA repair enzyme xeroderma pigmentosum protein A (XPA), and other C2H2, C3H and C4 zinc finger proteins including members of the steroid receptor superfamily (e.g. glucocorticoid receptor). Macromolecules to which arsenite does not bind to include calf thymus DNA, mixed Type II-A histones and bovine H3/H4 histone. Although all six tested arsenicals released iron from ferritin, radioactive arsenite did not bind to the protein horse ferritin. JF - Journal of inorganic biochemistry AU - Kitchin, Kirk T AU - Wallace, Kathleen AD - Environmental Carcinogenesis Division, Mail Drop B143-06, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. kitchin.kirk@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 532 EP - 539 VL - 102 IS - 3 SN - 0162-0134, 0162-0134 KW - Proteins KW - 0 KW - Methyltransferases KW - EC 2.1.1.- KW - Poly(ADP-ribose) Polymerases KW - EC 2.4.2.30 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Animals KW - Humans KW - Neoplasms -- chemically induced KW - Methyltransferases -- metabolism KW - Protein Binding KW - Poly(ADP-ribose) Polymerases -- metabolism KW - Models, Biological KW - Neoplasms -- metabolism KW - Arsenic -- toxicity KW - Arsenic -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70329017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+inorganic+biochemistry&rft.atitle=The+role+of+protein+binding+of+trivalent+arsenicals+in+arsenic+carcinogenesis+and+toxicity.&rft.au=Kitchin%2C+Kirk+T%3BWallace%2C+Kathleen&rft.aulast=Kitchin&rft.aufirst=Kirk&rft.date=2008-03-01&rft.volume=102&rft.issue=3&rft.spage=532&rft.isbn=&rft.btitle=&rft.title=Journal+of+inorganic+biochemistry&rft.issn=01620134&rft_id=info:doi/10.1016%2Fj.jinorgbio.2007.10.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-16 N1 - Date created - 2008-02-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.jinorgbio.2007.10.021 ER - TY - JOUR T1 - Evaluation of evidence for infection as a mode of action for induction of rat lymphoma. AN - 70326639; 18095346 AB - The European Food Safety Authority (EFSA) released a 2006 report questioning the relationship of aspartame exposure with increased incidence of lymphomas/leukemias in a European Ramazzini Foundation (ERF) rat study. The EFSA report suggested that the lymphoma/leukemia findings were most likely explained by infection in the rat colony. The ERF has also conducted the only available long-term oral study of methyl tertiary-butyl ether (MTBE). Thus, using the EFSA report as support, some have now raised questions about the human relevance of MTBE-associated hemolymphoreticular tumors reported by the ERF in female rats as well as whether their incidence was elevated above background levels. In this report, we discuss the hypothesized mode of action (MOA) of infection-induced lymphoma and its relevance to MTBE-associated lymphomas. We address the relationship of rat strain and study duration to lymphoma susceptibility and review evidence of low background rates of this tumor in control animals at the ERF, similar survival rates for female rats at the ERF and National Toxicology Program (NTP), and chemical- and gender-specificity of tumor induction for this type of tumor in studies at the ERF. We find that the background incidence of hemolymphoreticular tumors in female rats in the MTBE study is consistent with contemporaneous studies at the ERF and that there is an exposure-related effect, which is unlikely to be due to infections. We examine more recent tumor classification schemes for lymphomas, which support the combination of lymphoblastic leukemias and lymphomas reported by Belpoggi et al. ([1995] Toxicol Ind Health 11:119-149; [1998] Eur J Oncol 3:201-206). Published 2007 Wiley-Liss, Inc. JF - Environmental and molecular mutagenesis AU - Caldwell, Jane C AU - Jinot, Jennifer AU - DeVoney, Danielle AU - Gift, Jeff S AD - National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC, USA. caldwell.jane@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 155 EP - 164 VL - 49 IS - 2 SN - 0893-6692, 0893-6692 KW - Carcinogens KW - 0 KW - Methyl Ethers KW - methyl tert-butyl ether KW - 29I4YB3S89 KW - Index Medicus KW - Rats KW - Animals KW - Leukemia -- etiology KW - Lymphoma -- etiology KW - Methyl Ethers -- toxicity KW - Carcinogens -- toxicity KW - Infection -- complications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70326639?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+and+molecular+mutagenesis&rft.atitle=Evaluation+of+evidence+for+infection+as+a+mode+of+action+for+induction+of+rat+lymphoma.&rft.au=Caldwell%2C+Jane+C%3BJinot%2C+Jennifer%3BDeVoney%2C+Danielle%3BGift%2C+Jeff+S&rft.aulast=Caldwell&rft.aufirst=Jane&rft.date=2008-03-01&rft.volume=49&rft.issue=2&rft.spage=155&rft.isbn=&rft.btitle=&rft.title=Environmental+and+molecular+mutagenesis&rft.issn=08936692&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-24 N1 - Date created - 2008-02-25 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Environ Mol Mutagen. 2009 Jan;50(1):4-5; author reply 6-9 [19107900] Environ Mol Mutagen. 2009 Jan;50(1):1-3; author reply 6-9 [19107899] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - An evaluation of the mode of action framework for mutagenic carcinogens case study: Cyclophosphamide. AN - 70325581; 18240158 AB - In response to the 2005 revised US Environmental Protection Agency (EPA) Cancer Guidelines, a Risk Assessment Forum's Technical Panel has devised a strategy in which genetic toxicology data combined with other information are assessed to determine whether a carcinogen operates through a mutagenic mode of action (MOA). This information is necessary for EPA to decide whether age-dependent adjustment factors (ADAFs) should be applied to the cancer risk assessment. A decision tree has been developed as a part of this approach and outlines the critical steps for analyzing a compound for carcinogenicity through a mutagenic MOA (e.g., data analysis, determination of mutagenicity in animals and in humans). Agents, showing mutagenicity in animals and humans, proceed through the Agency's framework analysis for MOAs. Cyclophosphamide (CP), an antineoplastic agent, which is carcinogenic in animals and humans and mutagenic in vitro and in vivo, was selected as a case study to illustrate how the framework analysis would be applied to prove that a carcinogen operates through a mutagenic MOA. Consistent positive results have been seen for mutagenic activity in numerous in vitro assays, in animals (mice, rats, and hamsters) and in humans. Accordingly, CP was processed through the framework analysis and key steps leading to tumor formation were identified as follows: metabolism of the parent compound to alkylating metabolites, DNA damage followed by induction of multiple adverse genetic events, cell proliferation, and bladder tumors. Genetic changes in rats (sister chromatid exchanges at 0.62 mg/kg) can commence within 30 min and in cancer patients, chromosome aberrations at 35 mg/kg are seen by 1 hr, well within the timeframe and tumorigenic dose range for early events. Supporting evidence is also found for cell proliferation, indicating that mutagenicity, associated with cytotoxicity, leads to a proliferative response, which occurs early (48 hr) in the process of tumor induction. Overall, the weight of evidence evaluation supports CP acting through a mutagenic MOA. In addition, no data were found that an alternative MOA might be operative. Therefore, the cancer guidelines recommend a linear extrapolation for the risk assessment. Additionally, data exist showing that CP induces mutagenicity in fetal blood and in the peripheral blood of pediatric patients; thus, the ADAFs would be applied. Published 2008 Wiley-Liss, Inc. JF - Environmental and molecular mutagenesis AU - McCarroll, Nancy AU - Keshava, Nagalakshmi AU - Cimino, Michael AU - Chu, Margaret AU - Dearfield, Kerry AU - Keshava, Channa AU - Kligerman, Andrew AU - Owen, Russell AU - Protzel, Alberto AU - Putzrath, Resha AU - Schoeny, Rita AD - Health Effects Division, Office of Pesticide Programs (OPP), US Environmental Protection Agency, Washington, DC 20460, USA. mccarroll.nancy@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 117 EP - 131 VL - 49 IS - 2 SN - 0893-6692, 0893-6692 KW - Carcinogens KW - 0 KW - Mutagens KW - Cyclophosphamide KW - 8N3DW7272P KW - Index Medicus KW - Animals KW - Mutagenicity Tests KW - Humans KW - Guidelines as Topic KW - Neoplasms -- chemically induced KW - Carcinogens -- toxicity KW - Mutagens -- toxicity KW - Cyclophosphamide -- toxicity KW - Risk Assessment -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70325581?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+and+molecular+mutagenesis&rft.atitle=An+evaluation+of+the+mode+of+action+framework+for+mutagenic+carcinogens+case+study%3A+Cyclophosphamide.&rft.au=McCarroll%2C+Nancy%3BKeshava%2C+Nagalakshmi%3BCimino%2C+Michael%3BChu%2C+Margaret%3BDearfield%2C+Kerry%3BKeshava%2C+Channa%3BKligerman%2C+Andrew%3BOwen%2C+Russell%3BProtzel%2C+Alberto%3BPutzrath%2C+Resha%3BSchoeny%2C+Rita&rft.aulast=McCarroll&rft.aufirst=Nancy&rft.date=2008-03-01&rft.volume=49&rft.issue=2&rft.spage=117&rft.isbn=&rft.btitle=&rft.title=Environmental+and+molecular+mutagenesis&rft.issn=08936692&rft_id=info:doi/10.1002%2Fem.20372 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-24 N1 - Date created - 2008-02-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/em.20372 ER - TY - JOUR T1 - Difficulty of mode of action determination for trichloroethylene: An example of complex interactions of metabolites and other chemical exposures. AN - 70323777; 17973308 AB - The mode(s) of action (MOA) of a pollutant for adverse health effects may be dependent on the mixture of metabolites resulting from exposure to a single agent and may also be affected by coexposure to pollutants that have similar targets or affected pathways. Trichloroethylene (TCE) can be an useful example for illustration of the complexity coexposure can present to elucidation of the MOA of an agent. TCE exposure has been associated with increased risk of liver and kidney cancer in both laboratory animal and epidemiologic studies. There are a number of TCE metabolites that could play a role in the induction of these effects. Coexposures of other chemicals with TCE typically occurs as a result of environmental cocontamination that include its own metabolites, such as trichloroacetic acid, dichloroacetic acid, and other pollutants with similar metabolites such as perchloroethylene. Behaviors such as alcohol consumption can also potentially modify TCE toxicity through similar MOAs. The U.S. Environmental Protection Agency (EPA)'s 2001 draft TCE risk assessment, Trichloroethylene (TCE) Health Risk Assessment: Synthesis and Characterization, concluded that it was difficult to determine which of the metabolites of TCE may be responsible for these effects, what key events in their hypothesized MOAs are involved, and the relevance of some of the hypothesized MOAs to humans. Since the publication of U.S. EPA's draft TCE assessment, several studies have been conducted to understand the effects of coexposures to TCE. They cover both pharmacodynamic and pharmacokinetic considerations. This article highlights some of the recently published scientific literature on toxicological interactions between TCE, its metabolites, and other coexposures, including solvents, haloacetates, and ethanol. These studies give insight into both the potential MOAs of TCE exposure itself and putative modulators of TCE toxicity, and illustrate the difficulties encountered in determining the MOAs and modulators of toxicity for pollutants with such complex metabolism and coexposures. JF - Environmental and molecular mutagenesis AU - Caldwell, Jane C AU - Keshava, Nagalakshmi AU - Evans, Marina V AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, USA. caldwell.jane@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 142 EP - 154 VL - 49 IS - 2 SN - 0893-6692, 0893-6692 KW - Acetates KW - 0 KW - Solvents KW - Trichloroethylene KW - 290YE8AR51 KW - Ethanol KW - 3K9958V90M KW - Chloroform KW - 7V31YC746X KW - Carbon Tetrachloride KW - CL2T97X0V0 KW - Index Medicus KW - Animals KW - Drug Interactions KW - Humans KW - Ethanol -- toxicity KW - Chloroform -- toxicity KW - Carbon Tetrachloride -- toxicity KW - Acetates -- toxicity KW - Risk Assessment KW - Solvents -- toxicity KW - Trichloroethylene -- pharmacokinetics KW - Solvents -- pharmacokinetics KW - Trichloroethylene -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70323777?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+and+molecular+mutagenesis&rft.atitle=Difficulty+of+mode+of+action+determination+for+trichloroethylene%3A+An+example+of+complex+interactions+of+metabolites+and+other+chemical+exposures.&rft.au=Caldwell%2C+Jane+C%3BKeshava%2C+Nagalakshmi%3BEvans%2C+Marina+V&rft.aulast=Caldwell&rft.aufirst=Jane&rft.date=2008-03-01&rft.volume=49&rft.issue=2&rft.spage=142&rft.isbn=&rft.btitle=&rft.title=Environmental+and+molecular+mutagenesis&rft.issn=08936692&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-24 N1 - Date created - 2008-02-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Understanding mechanisms of toxicity: insights from drug discovery research. AN - 70311256; 18063003 AB - Toxicology continues to rely heavily on use of animal testing for prediction of potential for toxicity in humans. Where mechanisms of toxicity have been elucidated, for example endocrine disruption by xenoestrogens binding to the estrogen receptor, in vitro assays have been developed as surrogate assays for toxicity prediction. This mechanistic information can be combined with other data such as exposure levels to inform a risk assessment for the chemical. However, there remains a paucity of such mechanistic assays due at least in part to lack of methods to determine specific mechanisms of toxicity for many toxicants. A means to address this deficiency lies in utilization of a vast repertoire of tools developed by the drug discovery industry for interrogating the bioactivity of chemicals. This review describes the application of high-throughput screening assays as experimental tools for profiling chemicals for potential for toxicity and understanding underlying mechanisms. The accessibility of broad panels of assays covering an array of protein families permits evaluation of chemicals for their ability to directly modulate many potential targets of toxicity. In addition, advances in cell-based screening have yielded tools capable of reporting the effects of chemicals on numerous critical cell signaling pathways and cell health parameters. Novel, more complex cellular systems are being used to model mammalian tissues and the consequences of compound treatment. Finally, high-throughput technology is being applied to model organism screens to understand mechanisms of toxicity. However, a number of formidable challenges to these methods remain to be overcome before they are widely applicable. Integration of successful approaches will contribute towards building a systems approach to toxicology that will provide mechanistic understanding of the effects of chemicals on biological systems and aid in rationale risk assessments. JF - Toxicology and applied pharmacology AU - Houck, Keith A AU - Kavlock, Robert J AD - National Center for Computational Toxicology, Office Research and Development, United Stated Environmental Protection Agency, Research Triangle Park, NC 27711, USA. houck.keith@epa.gov Y1 - 2008/03/01/ PY - 2008 DA - 2008 Mar 01 SP - 163 EP - 178 VL - 227 IS - 2 SN - 0041-008X, 0041-008X KW - Index Medicus KW - Animals KW - Humans KW - Data Interpretation, Statistical KW - Drug Evaluation, Preclinical KW - Drug Design KW - Pharmacology -- trends KW - Drug-Related Side Effects and Adverse Reactions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70311256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Understanding+mechanisms+of+toxicity%3A+insights+from+drug+discovery+research.&rft.au=Houck%2C+Keith+A%3BKavlock%2C+Robert+J&rft.aulast=Houck&rft.aufirst=Keith&rft.date=2008-03-01&rft.volume=227&rft.issue=2&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-31 N1 - Date created - 2008-02-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Pesticide loadings of select organophosphate and pyrethroid pesticides in urban public housing. AN - 70307856; 17495869 AB - We investigated the magnitude and distribution of pyrethroid and organophosphate pesticide loadings within public housing dwellings in Boston, Massachusetts and compared the results using various sampling methods. We collected dust matrices from living room and kitchen in 42 apartments and analyzed for eleven pyrethoids (e.g., permethrin and cyfluthrin) and two organophosphates (chlorpyrifos and diazinon) in house dust using GC/MS. Agreement between sampling methods were evaluated using Spearman correlations and Kappa statistics. Permethrin and chlorpyrifos were detected in kitchen floor wipes in all homes, followed in frequency of detects by diazinon (98%), cypermethrin (90%) and cyfluthrin (71%). At least six pesticides were detected in kitchen floor wipes in the majority of the homes (range 3-8). Positive and statistically significant correlations among dust matrices were observed between kitchen floor wipes and living room vacuum dust, including for diazinon (r=0.62) and cyfluthrin (r=0.69). Detection of several pesticides including banned or restricted use products in some public housing units, underscore the need for alternative pest management strategies that embrace the safe and judicious use of pest control products. JF - Journal of exposure science & environmental epidemiology AU - Julien, Rhona AU - Adamkiewicz, Gary AU - Levy, Jonathan I AU - Bennett, Deborah AU - Nishioka, Marcia AU - Spengler, John D AD - Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA. julien.rhona@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 167 EP - 174 VL - 18 IS - 2 KW - Air Pollutants KW - 0 KW - Dust KW - Insecticides KW - Organophosphates KW - Pesticides KW - Pyrethrins KW - Index Medicus KW - Pest Control -- legislation & jurisprudence KW - Floors and Floorcoverings KW - Air Pollution, Indoor -- analysis KW - Humans KW - Boston KW - Air Pollutants -- analysis KW - Longitudinal Studies KW - Urban Population KW - Quality Control KW - Pest Control -- methods KW - Pyrethrins -- administration & dosage KW - Pyrethrins -- analysis KW - Organophosphates -- administration & dosage KW - Dust -- analysis KW - Insecticides -- administration & dosage KW - Organophosphates -- analysis KW - Insecticides -- analysis KW - Public Housing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70307856?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+exposure+science+%26+environmental+epidemiology&rft.atitle=Pesticide+loadings+of+select+organophosphate+and+pyrethroid+pesticides+in+urban+public+housing.&rft.au=Julien%2C+Rhona%3BAdamkiewicz%2C+Gary%3BLevy%2C+Jonathan+I%3BBennett%2C+Deborah%3BNishioka%2C+Marcia%3BSpengler%2C+John+D&rft.aulast=Julien&rft.aufirst=Rhona&rft.date=2008-03-01&rft.volume=18&rft.issue=2&rft.spage=167&rft.isbn=&rft.btitle=&rft.title=Journal+of+exposure+science+%26+environmental+epidemiology&rft.issn=1559-064X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-10-22 N1 - Date created - 2008-02-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Predicting maternal rat and pup exposures: how different are they? AN - 70275753; 18024990 AB - Risk and safety assessments for early life exposures to environmental chemicals or pharmaceuticals based on cross-species extrapolation would greatly benefit from information on chemical dosimetry in the young. Although relevant toxicity studies involve exposures during multiple life stages, the mother's exposure dose is frequently used for extrapolation of rodent toxicity findings to humans and represents a substantial source of uncertainty. A compartmental pharmacokinetic model augmented with biological information on factors changing during lactation and early postweaning was developed. The model uses adult pharmacokinetics, milk distribution, and relevant postnatal biology to predict dosimetry in the young for chemicals. The model addressed three dosing strategies employed in toxicity studies (gavage, constant ppm diet, and adjusted ppm diet) and the impact of different pharmacokinetic properties such as rates of clearance, milk distribution, and volume of distribution on the pup exposure doses and internal dosimetry. Developmental delays in clearance and recirculation of chemical in excreta from the pup to mother were evaluated. Following comparison with data for two chemicals, predictions were made for theoretical chemicals with a range of characteristics. Pup exposure was generally lower than the mother's with a shorter half-life, lower milk transfer, larger volume of distribution, and gavage dosing, while higher with longer half-life, higher milk transfer, smaller volume of distribution, and dietary exposures. The present model demonstrated pup exposures do not always parallel the mother's. The model predictions can be used to help design early life toxicity and pharmacokinetic studies and better interpret study findings. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Yoon, Miyoung AU - Barton, Hugh A AD - National Research Council Research Associateship Program at U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27709, USA. Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 15 EP - 32 VL - 102 IS - 1 SN - 1096-6080, 1096-6080 KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - Aging -- metabolism KW - Animals KW - Age Factors KW - Reproducibility of Results KW - Body Burden KW - Intubation, Gastrointestinal KW - Tissue Distribution KW - Risk Assessment KW - Pregnancy KW - Rats KW - Body Weight KW - Eating KW - Animals, Newborn KW - Milk -- metabolism KW - Half-Life KW - Diet KW - Female KW - Environmental Pollutants -- toxicity KW - Computer Simulation KW - Lactation -- metabolism KW - Toxicity Tests -- methods KW - Models, Biological KW - Environmental Pollutants -- administration & dosage KW - Environmental Pollutants -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70275753?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Predicting+maternal+rat+and+pup+exposures%3A+how+different+are+they%3F&rft.au=Yoon%2C+Miyoung%3BBarton%2C+Hugh+A&rft.aulast=Yoon&rft.aufirst=Miyoung&rft.date=2008-03-01&rft.volume=102&rft.issue=1&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-10 N1 - Date created - 2008-02-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Differences in allergenic potential of food extracts following oral exposure in mice reflect differences in digestibility: potential approaches to safety assessment. AN - 70274524; 18033772 AB - An animal model for food allergy is needed to assess genetically modified food crops for potential allergenicity. The ideal model must produce allergic antibody (IgE) to proteins differentially according to known allergenicity before being used to accurately identify potential allergens among novel proteins. The oral route is the most relevant for exposure to food antigens, and a protein's stability to digestion is a current risk assessment tool based on this natural route. However, normal laboratory animals do not mount allergic responses to proteins administered orally due to oral tolerance, an immunologic mechanism which specifically suppresses IgE. To circumvent oral tolerance and evoke differential IgE responses to a panel of allergenic and nonallergenic food extracts, female C3H/HeJ mice were exposed subcutaneously or orally with cholera toxin as an adjuvant. All foods elicited IgE by the subcutaneous route. Oral exposure, however, resulted in IgE to allergens (peanut, Brazil nut, and egg white) but not to nonallergens (spinach and turkey), provided that the dose and exposures were limited. Additionally, in vitro digestibility assays demonstrated the presence of digestion-stable proteins in the allergenic food extracts but not in the nonallergenic foods. Our results suggest that the subcutaneous route is inadequate to distinguish allergens from nonallergens, but oral exposure under the appropriate experimental conditions will result in differential allergic responses in accordance with known allergenicity. Moreover, those foods containing digestion-resistant proteins provoke allergic responses in this model, supporting the current use of pepsin resistance in the decision tree for potential allergenicity assessment. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Bowman, Christal C AU - Selgrade, Maryjane K AD - Immunotoxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. bowman.christal@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 100 EP - 109 VL - 102 IS - 1 SN - 1096-6080, 1096-6080 KW - Adjuvants, Immunologic KW - 0 KW - Dietary Proteins KW - Immunoglobulin E KW - 37341-29-0 KW - Cholera Toxin KW - 9012-63-9 KW - Pepsin A KW - EC 3.4.23.1 KW - Index Medicus KW - Administration, Oral KW - Animals KW - Peanut Hypersensitivity -- physiopathology KW - Protein Denaturation KW - Disease Models, Animal KW - Egg Hypersensitivity -- immunology KW - Mice KW - Nut Hypersensitivity -- physiopathology KW - Risk Assessment KW - Adjuvants, Immunologic -- administration & dosage KW - Dose-Response Relationship, Immunologic KW - Peanut Hypersensitivity -- immunology KW - Cholera Toxin -- administration & dosage KW - Injections, Subcutaneous KW - Mice, Inbred C3H KW - Time Factors KW - Egg Hypersensitivity -- physiopathology KW - Pepsin A -- metabolism KW - Female KW - Nut Hypersensitivity -- immunology KW - Digestion KW - Dietary Proteins -- metabolism KW - Dietary Proteins -- administration & dosage KW - Immunoglobulin E -- blood KW - Food Hypersensitivity -- physiopathology KW - Food Hypersensitivity -- immunology KW - Food, Genetically Modified KW - Immune Tolerance KW - Dietary Proteins -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70274524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Differences+in+allergenic+potential+of+food+extracts+following+oral+exposure+in+mice+reflect+differences+in+digestibility%3A+potential+approaches+to+safety+assessment.&rft.au=Bowman%2C+Christal+C%3BSelgrade%2C+Maryjane+K&rft.aulast=Bowman&rft.aufirst=Christal&rft.date=2008-03-01&rft.volume=102&rft.issue=1&rft.spage=100&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-10 N1 - Date created - 2008-02-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Speciation, characterization, and mobility of As, Se, and Hg in flue gas desulphurization residues. AN - 69149073; 18441822 AB - Flue gas from coal combustion contains significant amounts of volatile toxic trace elements such as arsenic (As), selenium (Se), and mercury (Hg). The capture of these elements in the flue gas desulphurization (FGD) scrubber unit has resulted in generation of a metal-laden residue. With increasing reuse of the FGD residues in beneficial applications, it is important to determine metal speciation and mobilityto understand the environmental impact of its reuse. In this paper, we report the solid phase speciation of As, Se, and Hg in FGD residues using X-ray absorption spectroscopy (XAS), X-ray fluorescence spectroscopy (XRF), and sequential chemical extraction (SCE) techniques. The SCE results combined with XRF data indicated a strong possibility of As association with iron oxides, whereas Se was distributed among all geochemical phases. Hg appeared to be mainly distributed in the strong-complexed phase. XRF images also suggested a strong association of Hg with Fe oxide materials within FGD residues. XAS analysis indicated that As existed in its oxidized state (As(V)), whereas Se and Hg was observed in primarily reduced states as selenite (Se(IV)) and Hg(I), respectively. The results from the SCE and variable pH leaching tests indicated that the labile fractions of As, Se, and Hg were fairly low and thus suggestive of their stability in the FGD residues. However, the presence of a fine fraction enriched in metal content in the FGD residue suggested that size fractionation is important in assessing the environmental risks associated with their reuse. JF - Environmental science & technology AU - Al-Abed, Souhail R AU - Jegadeesan, Gautham AU - Scheckel, Kirk G AU - Tolaymat, Thabet AD - National Risk Management Research Laboratory, United States Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, Ohio 45268, USA. al-abed.souhail@epa.gov Y1 - 2008/03/01/ PY - 2008 DA - 2008 Mar 01 SP - 1693 EP - 1698 VL - 42 IS - 5 SN - 0013-936X, 0013-936X KW - Gases KW - 0 KW - Mercury KW - FXS1BY2PGL KW - Selenium KW - H6241UJ22B KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - X-Rays KW - Fluorescence KW - Spectrum Analysis -- methods KW - Selenium -- chemistry KW - Mercury -- classification KW - Arsenic -- chemistry KW - Selenium -- classification KW - Mercury -- chemistry KW - Arsenic -- classification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69149073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Speciation%2C+characterization%2C+and+mobility+of+As%2C+Se%2C+and+Hg+in+flue+gas+desulphurization+residues.&rft.au=Al-Abed%2C+Souhail+R%3BJegadeesan%2C+Gautham%3BScheckel%2C+Kirk+G%3BTolaymat%2C+Thabet&rft.aulast=Al-Abed&rft.aufirst=Souhail&rft.date=2008-03-01&rft.volume=42&rft.issue=5&rft.spage=1693&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-31 N1 - Date created - 2008-04-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Assessment of landfill leachate volume and concentrations of cyanide and fluoride during phytoremediation AN - 50617740; 2008-114419 JF - Bioremediation Journal AU - Kang, Dong-Hee AU - Tsao, David AU - Wang-Cahill, Fan AU - Rock, Steve AU - Schwab, A P AU - Banks, M K Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 32 EP - 45 PB - Taylor & Francis, Philadelphia, PA VL - 12 IS - 1 SN - 1088-9868, 1088-9868 KW - halides KW - Spermatophyta KW - topsoil KW - fluorides KW - degradation KW - landfills KW - rhizosphere KW - Dicotyledoneae KW - remediation KW - ground water KW - bioaccumulation KW - Platanus KW - toxicity KW - leachate KW - Salix KW - phytoremediation KW - chemical composition KW - Fraxinus KW - soils KW - concentration KW - Plantae KW - pollutants KW - pollution KW - rates KW - migration of elements KW - bioremediation KW - trees KW - waste disposal KW - cyanides KW - Angiospermae KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50617740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioremediation+Journal&rft.atitle=Assessment+of+landfill+leachate+volume+and+concentrations+of+cyanide+and+fluoride+during+phytoremediation&rft.au=Kang%2C+Dong-Hee%3BTsao%2C+David%3BWang-Cahill%2C+Fan%3BRock%2C+Steve%3BSchwab%2C+A+P%3BBanks%2C+M+K&rft.aulast=Kang&rft.aufirst=Dong-Hee&rft.date=2008-03-01&rft.volume=12&rft.issue=1&rft.spage=32&rft.isbn=&rft.btitle=&rft.title=Bioremediation+Journal&rft.issn=10889868&rft_id=info:doi/10.1080%2F10889860701866297 L2 - http://www.informaworld.com/smpp/title~content=t713400853 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 50 N1 - PubXState - PA N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Angiospermae; bioaccumulation; bioremediation; chemical composition; concentration; cyanides; degradation; Dicotyledoneae; fluorides; Fraxinus; ground water; halides; landfills; leachate; migration of elements; phytoremediation; Plantae; Platanus; pollutants; pollution; rates; remediation; rhizosphere; Salix; soils; Spermatophyta; topsoil; toxicity; trees; waste disposal DO - http://dx.doi.org/10.1080/10889860701866297 ER - TY - JOUR T1 - Benthic fluxes of mercury species in a lagoon environment (Grado Lagoon, northern Adriatic Sea, Italy) AN - 50472808; 2009-036265 AB - The role of the major biogeochemical processes in Hg cycling at the sediment-water interface was investigated in the Grado Lagoon (Northern Adriatic Sea). This wetland system has been extensively contaminated from the Idrija Hg Mine (Slovenia) through the Isonzo River suspended load carried by tidal fluxes. Three approaches were used to study the sediment-water exchange of total Hg (THg), methylmercury (MeHg), reactive Hg (RHg) and dissolved gaseous Hg (DGHg): (1) estimation of diffusive fluxes from porewater and overlying water concentrations, (2) measurements of benthic fluxes using a deployed light benthic chamber in situ and (3) measurements of benthic fluxes during oxic-anoxic transition with a laboratory incubation experiment. The THg solid phase, ranging between 9.5 and 14.4 mu g g (super -1) , showed slight variability with depth and time. Conversely, MeHg contents were highest (up to 21.9 ng g (super -1) ) at the surface; they tended to decrease to nearly zero concentration with depth, thus suggesting that MeHg production and accumulation occur predominantly just below the sediment-water interface. Porewater MeHg concentrations (0.9-7.9 ng L (super -1) , 0.15-15% of THg) varied seasonally; higher contents were observed in the warmer period. The MeHg diffusive fluxes (up to 17 ng m (super -2) day (super -1) ) were similar to those in the nearby Gulf of Trieste [Covelli, S., Horvat, M., Faganeli, J., Brambati, A., 1999. Porewater distribution and benthic flux of mercury and methylmercury in the Gulf of Trieste (Northern Adriatic Sea). Estuar. Coast. Shelf Sci. 48, 415-428], although the lagoon sediments contained four-fold higher THg concentrations. Conversely, the THg diffusive fluxes in the lagoon (up to 110 ng m (super -2) day (super -1) ) were one- to two-fold higher than those previously estimated for the Gulf of Trieste. The diurnal MeHg benthic fluxes were highest in summer at both sites (41,000 and 33,000 ng m (super -2) day (super -1) at the fishfarm and in the open lagoon, respectively), thus indicating the influence of temperature on microbial processes. The diurnal variations of dissolved THg and especially MeHg were positively correlated with O (sub 2) and inversely with DIC, suggesting an important influence of benthic photosynthetic activities on lagoon benthic Hg cycling, possibly through the production of organic matter promptly available for methylation. The results from the dark chamber incubated in the laboratory showed that the regeneration of dissolved THg was slightly affected by the oxic-anoxic transition. Conversely, the benthic flux of MeHg was up to 15-fold higher in sediments overlain by O (sub 2) depleted waters. In the anoxic phase, the MeHg fluxes proceeded in parallel with Fe fluxes and the methylated form reached approximately 100% of dissolved THg. The MeHg is mostly released into overlying water (mean recycling efficiency of 89%) until the occurrence of sulphide inhibition, due to scavenging of the available Hg substrate for methylation. The results suggest that sediments in the Grado Lagoon, especially during anoxic events, should be considered as a primary source of MeHg for the water column. JF - Applied Geochemistry AU - Covelli, Stefano AU - Faganeli, Jadran AU - De Vittor, Cinzia AU - Predonzani, Sergio AU - Acquavita, Alessandro AU - Horvat, Milena A2 - Gustin, Mae Sexauer A2 - Kolker, Allan A2 - Gardfeldt, Katarina Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 529 EP - 546 PB - Elsevier, Oxford-New York-Beijing VL - 23 IS - 3 SN - 0883-2927, 0883-2927 KW - photosynthesis KW - Adriatic Sea KW - Europe KW - ecosystems KW - environmental analysis KW - Italy KW - Friuli-Venezia Giulia Italy KW - Southern Europe KW - ground water KW - water-rock interaction KW - Gulf of Trieste KW - movement KW - chemical composition KW - water pollution KW - mercury KW - mercury ores KW - shore features KW - experimental studies KW - Slovenia KW - acid mine drainage KW - pollutants KW - surface water KW - photochemistry KW - Trieste Italy KW - pollution KW - Idrija Mine KW - organo-metallics KW - East Mediterranean KW - methylmercury KW - wetlands KW - metals KW - metal ores KW - Mediterranean Sea KW - lagoons KW - pore water KW - Grado Lagoon KW - lake sediments KW - 02B:Hydrochemistry KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50472808?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Geochemistry&rft.atitle=Benthic+fluxes+of+mercury+species+in+a+lagoon+environment+%28Grado+Lagoon%2C+northern+Adriatic+Sea%2C+Italy%29&rft.au=Covelli%2C+Stefano%3BFaganeli%2C+Jadran%3BDe+Vittor%2C+Cinzia%3BPredonzani%2C+Sergio%3BAcquavita%2C+Alessandro%3BHorvat%2C+Milena&rft.aulast=Covelli&rft.aufirst=Stefano&rft.date=2008-03-01&rft.volume=23&rft.issue=3&rft.spage=529&rft.isbn=&rft.btitle=&rft.title=Applied+Geochemistry&rft.issn=08832927&rft_id=info:doi/10.1016%2Fj.apgeochem.2007.12.011 L2 - http://www.sciencedirect.com/science/journal/08832927 LA - English DB - GeoRef N1 - Conference title - Transport and fate of mercury in the environment N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2009-01-01 N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - acid mine drainage; Adriatic Sea; chemical composition; East Mediterranean; ecosystems; environmental analysis; Europe; experimental studies; Friuli-Venezia Giulia Italy; Grado Lagoon; ground water; Gulf of Trieste; Idrija Mine; Italy; lagoons; lake sediments; Mediterranean Sea; mercury; mercury ores; metal ores; metals; methylmercury; movement; organo-metallics; photochemistry; photosynthesis; pollutants; pollution; pore water; shore features; Slovenia; Southern Europe; surface water; Trieste Italy; water pollution; water-rock interaction; wetlands DO - http://dx.doi.org/10.1016/j.apgeochem.2007.12.011 ER - TY - JOUR T1 - Land degradation and poverty AN - 36859229; 3530459 JF - Geographical research AU - Conacher, Arthur AU - De, Nguyen Van AU - Douglas, Ian AU - McMorrow, Julia AU - Lindley, Sarah AU - Binh, Dao Kim Nguyen Thuy AU - Van, Tran Thi AU - Thanh, Le Huu AU - Tho, Nguyen AU - Phuong, Le T.V. AU - Trung, Nguyen Dai AU - Verdoodt, Ann AU - Dusar, Michiel AU - Van, Tran Tan AU - Ranst, Eric Van AU - Rowntree, K M AU - Fox, R C AU - Konstadakopulos, Dimitrios AU - Hue, Le Thi Van AU - Scott, Steffanie AU - Fisher, Robert AU - Hirsch, Philip AD - University of Western Australia ; Vietnamese Academy of Science and Technology ; University of Manchester ; Vietnam National University ; Ho Chi Minh City Environmental Protection Agency ; Vietnam Institute of Geosciences and Mineral Resources ; Ghent University ; Royal Belgian Institute of Natural Sciences ; Rhodes University ; University of the West of England, Bristol ; Hanoi University of Science ; University of Waterloo ; University of Sydney Y1 - 2008/03// PY - 2008 DA - Mar 2008 VL - 46 IS - 1 SN - 1745-5863, 1745-5863 KW - Sociology KW - Economics KW - Agriculture KW - Cultivation practices KW - Environmental degradation KW - Social organization KW - Learning KW - Causal analysis KW - Soil erosion KW - Resource depletion KW - Knowledge KW - Land use KW - Socioeconomic development KW - Poverty KW - Developing countries KW - Farming methods KW - Local communities KW - Rural areas UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36859229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geographical+research&rft.atitle=Land+degradation+and+poverty&rft.au=Conacher%2C+Arthur%3BDe%2C+Nguyen+Van%3BDouglas%2C+Ian%3BMcMorrow%2C+Julia%3BLindley%2C+Sarah%3BBinh%2C+Dao+Kim+Nguyen+Thuy%3BVan%2C+Tran+Thi%3BThanh%2C+Le+Huu%3BTho%2C+Nguyen%3BPhuong%2C+Le+T.V.%3BTrung%2C+Nguyen+Dai%3BVerdoodt%2C+Ann%3BDusar%2C+Michiel%3BVan%2C+Tran+Tan%3BRanst%2C+Eric+Van%3BRowntree%2C+K+M%3BFox%2C+R+C%3BKonstadakopulos%2C+Dimitrios%3BHue%2C+Le+Thi+Van%3BScott%2C+Steffanie%3BFisher%2C+Robert%3BHirsch%2C+Philip&rft.aulast=Conacher&rft.aufirst=Arthur&rft.date=2008-03-01&rft.volume=46&rft.issue=1&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Geographical+research&rft.issn=17455863&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Collection of 7 articles N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 4314 4313 4309; 12051 12058; 9962; 7217 7201 4025; 2085 971 2088 10642 2688 2449 10404; 7495 2603; 7073; 4814; 3082; 7278 12929 7073; 11878 9003; 827; 10957 10958 4642; 11156 1247; 3480 2958 12092; 11987 3483 ER - TY - JOUR T1 - Erosion and nutrient loss on sloping land under intense cultivation in Southern Vietnam AN - 36857347; 3530133 AB - To help improve the well-being of the local people, a joint Vietnamese-UK team set out to establish a way of estimating soil and nutrient losses under different land management scenarios, using field data extrapolated through remote sensing and GIS, to obtain catchment-wide estimates of the impact of land cover change. Immigration from remote provinces to the Dong Phu District of Binh Phuóc Province, about 120 km north of Ho Chi Minh City, has led to disruption of soil surface stability on easily eroded clayey sandstones, creating rapid nutrient depletion that affects crop yields and siltation in the channel of the Rach Rat river downstream. The poor farmers of the areas see crop yields drop dramatically after two or three years of cultivation due to the fertility decline. Soil loss varies dramatically between wet season and dry season and with ground cover. Erosion bridge measurements showed a mean loss of 85.2 t ha-1 y-1 under cassava saplings with cashew nuts, 43.3 t ha-1 y-1 on uncultivated land and 41.7 t ha-1 y-1 under mature cassava. The rates of erosion were higher than those reported in many other parts of Vietnam, reflecting the high erodibility of the friable sandy soils on the steep side-slopes of the Rach Rat catchment. However, although the actual measurements provide better soil loss data than estimates based on the parameters of soil loss equations, a large number of measurement sites is needed to provide adequate coverage of the crop and slope combinations in this dissected terrain for good prediction using GIS and remote sensing. Reprinted by permission of Blackwell Publishers JF - Geographical research AU - De, Nguyen Van AU - Douglas, Ian AU - McMorrow, Julia AU - Lindley, Sarah AU - Binh, Dao Kim Nguyen Thuy AU - Van, Tran Thi AU - Thanh, Le Huu AU - Tho, Nguyen AD - Vietnamese Academy of Science and Technology ; University of Manchester ; Vietnam National University ; Ho Chi Minh City Environmental Protection Agency Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 4 EP - 16 VL - 46 IS - 1 SN - 1745-5863, 1745-5863 KW - Sociology KW - Economics KW - Cultivation practices KW - Measurement KW - Poverty KW - Crop yield KW - Soil erosion KW - Nutrition KW - Land use KW - Vietnam KW - Geographical information systems UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36857347?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geographical+research&rft.atitle=Erosion+and+nutrient+loss+on+sloping+land+under+intense+cultivation+in+Southern+Vietnam&rft.au=De%2C+Nguyen+Van%3BDouglas%2C+Ian%3BMcMorrow%2C+Julia%3BLindley%2C+Sarah%3BBinh%2C+Dao+Kim+Nguyen+Thuy%3BVan%2C+Tran+Thi%3BThanh%2C+Le+Huu%3BTho%2C+Nguyen&rft.aulast=De&rft.aufirst=Nguyen&rft.date=2008-03-01&rft.volume=46&rft.issue=1&rft.spage=4&rft.isbn=&rft.btitle=&rft.title=Geographical+research&rft.issn=17455863&rft_id=info:doi/10.1111%2Fj.1745-5871.2007.00487.x LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 7217 7201 4025; 12051 12058; 8808; 3054 796 10242 3872 554 971; 3082; 7854; 5472 6537 6515; 9962; 449 393 30 DO - http://dx.doi.org/10.1111/j.1745-5871.2007.00487.x ER - TY - JOUR T1 - Local knowledge and economic realities affecting soil erosion in the rach rat catchment, Vietnam AN - 36853651; 3530134 AB - Several parts of Binh Phuóc Province, southern Vietnam, suffer from degraded soils and vegetation as a result of both natural erosion of weak mud rocks and sandstones and intensive human activity, especially through land clearing for agriculture on unstable slopes, deforestation, and abandonment of poor farmland. The underlying cause of this land degradation has been the farming habits of migrants of varying ethnic groups who have settled in the area since 1980. The indigenous farming knowledge of these people and the role of that knowledge in soil erosion were examined by a series of household surveys. They enabled farming practices to be related to ground cover established from a 2002 Landsat 7 ETM (Enhanced Thematic Mapper), and erosion data from a series of erosion bridge measurements. A GIS (Geographical Information System) approach was piloted as a means of identifying areas vulnerable to erosion. This could then be combined with the understanding of farming practices to reveal the relative roles of farmer behaviour, crop cover, and slope and soil characteristics in the erosion process. Land use, local people's knowledge and economic realities are the main factors, as well as natural conditions, that drive this land degradation. Reprinted by permission of Blackwell Publishers JF - Geographical research AU - Binh, Dao Kim Nguyen Thuy AU - Phuong, Le T.V. AU - Douglas, Ian AU - De, Nguyen Van AU - McMorrow, Julia AU - Lindley, Sarah AU - Van, Tran Thi AU - Thanh, Le Huu AU - Tho, Nguyen AD - Vietnamese Academy of Science and Technology ; University of Manchester ; Vietnam National University ; Ho Chi Minh City Environmental Protection Agency Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 17 EP - 26 VL - 46 IS - 1 SN - 1745-5863, 1745-5863 KW - Sociology KW - Economics KW - Environmental degradation KW - Surveys KW - Economic activity KW - Soil erosion KW - Ethnic groups KW - Farming methods KW - Vietnam KW - Indigenous knowledge UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36853651?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geographical+research&rft.atitle=Local+knowledge+and+economic+realities+affecting+soil+erosion+in+the+rach+rat+catchment%2C+Vietnam&rft.au=Binh%2C+Dao+Kim+Nguyen+Thuy%3BPhuong%2C+Le+T.V.%3BDouglas%2C+Ian%3BDe%2C+Nguyen+Van%3BMcMorrow%2C+Julia%3BLindley%2C+Sarah%3BVan%2C+Tran+Thi%3BThanh%2C+Le+Huu%3BTho%2C+Nguyen&rft.aulast=Binh&rft.aufirst=Dao+Kim+Nguyen&rft.date=2008-03-01&rft.volume=46&rft.issue=1&rft.spage=17&rft.isbn=&rft.btitle=&rft.title=Geographical+research&rft.issn=17455863&rft_id=info:doi/10.1111%2Fj.1745-5871.2007.00488.x LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12051 12058; 4814; 6310 7073; 4314 4313 4309; 4424; 12429; 3872 554 971; 449 393 30 DO - http://dx.doi.org/10.1111/j.1745-5871.2007.00488.x ER - TY - JOUR T1 - The applicaton of project aging appraisal mathematical model in channels of Guhai water-lifting project AN - 21018276; 8428313 AB - In the recent 30 years of the Guhai water-lifting project, shortage middle arid zone society and the economic development it has made great contribution to since the outly was shortage for a long time, the project facility cannot obtain the immediate service, aging day by day. To make a quantitive and science appraisal for project aging state, the aging appraisal mathematical model was built on the basis of long-term pratice and mathematical theory knowledge. It is the scientific decision-making basis for further reform and plan-making in channels of Guhai water-lifting project. JF - Ningxia Engineering Technology AU - Du, Y AU - Zhang, L AD - Ningxia Guhai Administrative Office of Water-lifting, Zhongning 755100, China Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 86 EP - 91 VL - 7 IS - 1 SN - 1671-7244, 1671-7244 KW - Aqualine Abstracts; Water Resources Abstracts KW - Mathematical Models KW - Arid Zone KW - Aging KW - Economic Development KW - Decision Making KW - Appraisals KW - Channels KW - AQ 00005:Underground Services and Water Use KW - SW 6010:Structures UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21018276?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ningxia+Engineering+Technology&rft.atitle=The+applicaton+of+project+aging+appraisal+mathematical+model+in+channels+of+Guhai+water-lifting+project&rft.au=Du%2C+Y%3BZhang%2C+L&rft.aulast=Du&rft.aufirst=Y&rft.date=2008-03-01&rft.volume=7&rft.issue=1&rft.spage=86&rft.isbn=&rft.btitle=&rft.title=Ningxia+Engineering+Technology&rft.issn=16717244&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-09-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Aging; Appraisals; Channels; Mathematical Models; Arid Zone; Economic Development; Decision Making ER - TY - JOUR T1 - Talk about Water Conservancy Science and Technology Periodical Management to Periodical Development AN - 20915585; 8374045 AB - Talking about the meaning of water conservancy science and technology periodicals management, analysis on the questions of periodicals management at present. From Politics, science, society benefit and economic benefit, the measurement of strengthening water conservancy science and technology periodicals management has been put forward. JF - Water Conservancy Science and Technology and Economy AU - Liu, Y-N AD - Editorial Office of Water Conservancy Science and Technology and Economy, Harbin 150001, China Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 256 EP - 257 VL - 14 IS - 3 SN - 1006-7175, 1006-7175 KW - Aqualine Abstracts KW - Benefits KW - Technology KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20915585?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Conservancy+Science+and+Technology+and+Economy&rft.atitle=Talk+about+Water+Conservancy+Science+and+Technology+Periodical+Management+to+Periodical+Development&rft.au=Liu%2C+Y-N&rft.aulast=Liu&rft.aufirst=Y-N&rft.date=2008-03-01&rft.volume=14&rft.issue=3&rft.spage=256&rft.isbn=&rft.btitle=&rft.title=Water+Conservancy+Science+and+Technology+and+Economy&rft.issn=10067175&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Benefits; Technology ER - TY - JOUR T1 - Human Influences on Water Quality in Great Lakes Coastal Wetlands AN - 20896350; 8157358 AB - A better understanding of relationships between human activities and water chemistry is needed to identify and manage sources of anthropogenic stress in Great Lakes coastal wetlands. The objective of the study described in this article was to characterize relationships between water chemistry and multiple classes of human activity (agriculture, population and development, point source pollution, and atmospheric deposition). We also evaluated the influence of geomorphology and biogeographic factors on stressor-water quality relationships. We collected water chemistry data from 98 coastal wetlands distributed along the United States shoreline of the Laurentian Great Lakes and GIS-based stressor data from the associated drainage basin to examine stressor-water quality relationships. The sampling captured broad ranges (1.5-2 orders of magnitude) in total phosphorus (TP), total nitrogen (TN), dissolved inorganic nitrogen (DIN), total suspended solids (TSS), chlorophyll a (Chl a), and chloride; concentrations were strongly correlated with stressor metrics. Hierarchical partitioning and all-subsets regression analyses were used to evaluate the independent influence of different stressor classes on water quality and to identify best predictive models. Results showed that all categories of stress influenced water quality and that the relative influence of different classes of disturbance varied among water quality parameters. Chloride exhibited the strongest relationships with stressors followed in order by TN, Chl a, TP, TSS, and DIN. In general, coarse scale classification of wetlands by morphology (three wetland classes: riverine, protected, open coastal) and biogeography (two ecoprovinces: Eastern Broadleaf Forest [EBF] and Laurentian Mixed Forest [LMF]) did not improve predictive models. This study provides strong evidence of the link between water chemistry and human stress in Great Lakes coastal wetlands and can be used to inform management efforts to improve water quality in Great Lakes coastal ecosystems. JF - Environmental Management AU - Morrice, John A AU - Danz, Nicholas P AU - Regal, Ronald R AU - Kelly, John R AU - Niemi, Gerald J AU - Reavie, Euan D AU - Hollenhorst, Tom AU - Axler, Richard P AU - Trebitz, Anett S AU - Cotter, Anne M AU - Peterson, Gregory S AD - U.S. Environmental Protection Agency, 6201 Congdon Boulevard, Duluth, MN, 55804, USA, morrice.john@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 347 EP - 357 PB - Springer-Verlag, 175 Fifth Ave. New York NY 10010 USA, [mailto:orders@springer-ny.com] VL - 41 IS - 3 SN - 0364-152X, 0364-152X KW - Pollution Abstracts; Sustainability Science Abstracts; Ecology Abstracts; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Meteorological & Geoastrophysical Abstracts KW - water quality KW - Ecosystems KW - Forests KW - Man-induced effects KW - Chloride KW - Water quality KW - point source pollution KW - Lakes KW - Geomorphology KW - Wetlands KW - Freshwater pollution KW - Atmospheric pollution KW - anthropogenic factors KW - Biogeography KW - Water Quality KW - Stress KW - Model Studies KW - Water management KW - Human factors KW - Nitrogen KW - Agriculture KW - Prediction KW - Chlorides KW - Anthropogenic factors KW - Mixed Forests KW - Regression analysis KW - Sampling KW - water chemistry KW - Drainage KW - Water pollution KW - USA KW - North America, Great Lakes KW - Morphology KW - geomorphology KW - Water chemistry KW - Q5 08503:Characteristics, behavior and fate KW - D 04070:Pollution KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development KW - SW 3020:Sources and fate of pollution KW - O 4080:Pollution - Control and Prevention KW - M2 556.11:Water properties (556.11) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20896350?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Management&rft.atitle=Human+Influences+on+Water+Quality+in+Great+Lakes+Coastal+Wetlands&rft.au=Morrice%2C+John+A%3BDanz%2C+Nicholas+P%3BRegal%2C+Ronald+R%3BKelly%2C+John+R%3BNiemi%2C+Gerald+J%3BReavie%2C+Euan+D%3BHollenhorst%2C+Tom%3BAxler%2C+Richard+P%3BTrebitz%2C+Anett+S%3BCotter%2C+Anne+M%3BPeterson%2C+Gregory+S&rft.aulast=Morrice&rft.aufirst=John&rft.date=2008-03-01&rft.volume=41&rft.issue=3&rft.spage=347&rft.isbn=&rft.btitle=&rft.title=Environmental+Management&rft.issn=0364152X&rft_id=info:doi/10.1007%2Fs00267-007-9055-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Prediction; Water management; Biogeography; Anthropogenic factors; Man-induced effects; Wetlands; Water quality; Water pollution; Freshwater pollution; Regression analysis; Forests; Stress; Chloride; Water chemistry; Nitrogen; Agriculture; Atmospheric pollution; Geomorphology; Ecosystems; Drainage; water quality; anthropogenic factors; water chemistry; Chlorides; point source pollution; Lakes; Morphology; geomorphology; Human factors; Water Quality; Sampling; Mixed Forests; Model Studies; USA; North America, Great Lakes DO - http://dx.doi.org/10.1007/s00267-007-9055-5 ER - TY - JOUR T1 - Overwintering habitats of migratory juvenile American shad in Chesapeake Bay AN - 20882393; 8150373 AB - We describe overwintering habitats of age-0 American shad in the lower Chesapeake Bay estuary through analyses of multiple, complementary data sets, including bottom-trawls of the Virginia portion of Chesapeake Bay and its tributaries, stable isotope analysis of American shad and common prey items, and stomach content analysis. This is the first detailed description of overwintering habitats used by young American shad during their first migration to the Atlantic Ocean. American shad generally migrated from their freshwater rearing habitat during November and December and migrated to the ocean during February through March. American shad were captured in all of Virginia's tributaries and along Chesapeake Bay's western coast. These fish were caught in relatively cool waters (5-9 degree C) over a wide range of salinities (0.1-27.5). Strong selection for certain temperatures or salinities was not apparent. Stomach content and stable isotope analyses demonstrated that juveniles were feeding in the estuary, growing on a diet of estuarine calanoid copepods, mysid shrimps, and larval fishes. The stable isotope data were used to describe temperature- and size-cued migration from fresh water. Temperature was an important cue affecting both the timing and the rate of migration. Further, American shad exhibited at least three different size-related migration behaviors: most juveniles emigrated from the freshwater rearing habitat at 2-5 g (ca. 55-75 mm fork length); other juveniles emigrated at a size of 2 g or less and rapidly moved into the lower estuary; and finally, a few juveniles remained in the upper estuary and did not emigrate until they were 5 g or larger. A few American shad were captured with anomalous stable isotope signatures, which may be explained by migration into the Chesapeake Bay estuary from an adjacent system. JF - Environmental Biology of Fishes AU - Hoffman, Joel C AU - Limburg, Karin E AU - Bronk, Deborah A AU - Olney, John E AD - Mid-Continent Ecology Division, 6201 Congdon Blvd, Duluth, MN, 55804, USA, Hoffman.Joel@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 329 EP - 345 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 81 IS - 3 SN - 0378-1909, 0378-1909 KW - Ecology Abstracts; Oceanic Abstracts KW - Isotopes KW - Freshwater KW - Migration KW - ANW, USA, Virginia KW - Copepoda KW - Tributaries KW - Fish culture KW - Temperature effects KW - Marine KW - Decapoda KW - Freshwater environments KW - Overwintering KW - Estuaries KW - Brackish KW - Habitat KW - Inland water environment KW - ANW, USA, Chesapeake Bay KW - A, Atlantic KW - Stomach content KW - Oceans KW - Migrations KW - Marine aquaculture KW - Freshwater aquaculture KW - O 1070:Ecology/Community Studies KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20882393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Biology+of+Fishes&rft.atitle=Overwintering+habitats+of+migratory+juvenile+American+shad+in+Chesapeake+Bay&rft.au=Hoffman%2C+Joel+C%3BLimburg%2C+Karin+E%3BBronk%2C+Deborah+A%3BOlney%2C+John+E&rft.aulast=Hoffman&rft.aufirst=Joel&rft.date=2008-03-01&rft.volume=81&rft.issue=3&rft.spage=329&rft.isbn=&rft.btitle=&rft.title=Environmental+Biology+of+Fishes&rft.issn=03781909&rft_id=info:doi/10.1007%2Fs10641-007-9204-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Decapoda; Copepoda; ANW, USA, Chesapeake Bay; ANW, USA, Virginia; A, Atlantic; Estuaries; Migrations; Overwintering; Freshwater aquaculture; Fish culture; Tributaries; Inland water environment; Marine aquaculture; Stomach content; Migration; Habitat; Isotopes; Freshwater environments; Oceans; Temperature effects; Marine; Brackish; Freshwater DO - http://dx.doi.org/10.1007/s10641-007-9204-y ER - TY - JOUR T1 - Ecosystem and decomposer effects on litter dynamics along an old field to old-growth forest successional gradient AN - 20852440; 8287234 AB - Identifying the biotic (e.g. decomposers, vegetation) and abiotic (e.g. temperature, moisture) mechanisms controlling litter decomposition is key to understanding ecosystem function, especially where variation in ecosystem structure due to successional processes may alter the strength of these mechanisms. To identify these controls and feedbacks, I measured mass loss and N flux in herbaceous, leaf, and wood litter along a successional gradient of ecosystem types (old field, transition forest, old-growth forest) while manipulating detritivore access to litter. Ecosystem type, litter type, and decomposers contributed directly and interactively to decomposition. Litter mass loss and N accumulation was higher while litter C:N remained lower in old-growth forests than in either old fields or transition forest. Old-growth forests influenced litter dynamics via microclimate (coolest and wettest) but also, apparently, through a decomposer community adapted to consuming the large standing stocks of leaf litter, as indicated by rapid leaf litter loss. In all ecosystem types, mass loss of herbaceous litter was greater than leaf litter which, in turn was greater than wood. However, net N loss from wood litter was faster than expected, suggesting localized N flux effects of wood litter. Restricting detritivore access to litter reduced litter mass loss and slowed the accumulation of N in litter, suggesting that macro-detritivores affect both physical and chemical characteristics of litter through selective grazing. These data suggest that the distinctive litter loss rates and efficient N cycling observed in old-growth forest ecosystems are not likely to be realized soon after old fields are restored to forested ecosystems. JF - Acta Oecologica AU - Mayer, P M Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 222 EP - 230 PB - Editions Scientifiques et Medicales Elsevier, 23 rue Linois 75724 Paris cedex 15 France, [URL:http://www.elsevier.fr] VL - 33 IS - 2 SN - 1146-609X, 1146-609X KW - Sustainability Science Abstracts; Ecology Abstracts KW - Temperature effects KW - Grazing KW - Forests KW - Decomposition KW - Leaf litter KW - Old fields KW - Microclimate KW - detritivores KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20852440?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+Oecologica&rft.atitle=Ecosystem+and+decomposer+effects+on+litter+dynamics+along+an+old+field+to+old-growth+forest+successional+gradient&rft.au=Mayer%2C+P+M&rft.aulast=Mayer&rft.aufirst=P&rft.date=2008-03-01&rft.volume=33&rft.issue=2&rft.spage=222&rft.isbn=&rft.btitle=&rft.title=Acta+Oecologica&rft.issn=1146609X&rft_id=info:doi/10.1016%2Fj.actao.2007.11.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Forests; Old fields; Leaf litter; detritivores; Decomposition; Grazing; Microclimate; Temperature effects DO - http://dx.doi.org/10.1016/j.actao.2007.11.001 ER - TY - JOUR T1 - Modeling and testing of reactive contaminant transport in drinking water pipes: Chlorine response and implications for online contaminant detection AN - 20816912; 8185196 AB - A modified one-dimensional Danckwerts convection-dispersion-reaction (CDR) model is numerically simulated to explain the observed chlorine residual loss for a ''slug'' of reactive contaminants instantaneously introduced into a drinking water pipe of assumed no or negligible wall demand. In response to longitudinal dispersion, a contaminant propagates into the bulk phase where it reacts with disinfectants in the water. This process generates a U-shaped pattern of chlorine residual loss in a time-series concentration plot. Numerical modeling indicates that the residual loss curve geometry (i.e., slope, depth, and width) is a function of several variables such as axial Peclet number, reaction rate constants, molar fraction of the fast- and slow-reacting contaminants, and the quasi-steady-state chlorine decay inside the ''slug'' which serves as a boundary condition of the CDR model. Longitudinal dispersion becomes dominant for less reactive contaminants. Pilot-scale pipe flow experiments for a non-reactive sodium fluoride tracer and the fast-reacting aldicarb, a pesticide, were conducted under turbulent flow conditions (Re=9020 and 25,000). Both the experimental results and the CDR modeling are in agreement showing a close relationship among the aldicarb contaminant ''slug'', chlorine residual loss and its variations, and a concentration increase of chloride as the final reaction product. Based on these findings, the residual loss curve and its geometry are useful tools to identify the presence of a contaminant ''slug'' and infer its reactive properties in adaptive contaminant detections. JF - Water Research AU - Jeffrey Yang, Y AU - Goodrich, JA AU - Clark, R M AU - Li, SY AD - US EPA National Risk Management Research Laboratory, 26W Martin Luther King Drive, Cincinnati, OH 45268, USA, yang.jeff@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 1397 EP - 1412 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 42 IS - 6-7 SN - 0043-1354, 0043-1354 KW - Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Chlorides KW - Tracers KW - Disinfectants KW - Drinking Water KW - Pollutants KW - Fluoride KW - Decay KW - Slopes KW - Pilot Plants KW - Pipes KW - Mathematical models KW - boundary conditions KW - Model Studies KW - Sodium KW - Pesticides KW - Chlorination KW - Drinking water KW - Contaminants KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - AQ 00004:Water Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20816912?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Research&rft.atitle=Modeling+and+testing+of+reactive+contaminant+transport+in+drinking+water+pipes%3A+Chlorine+response+and+implications+for+online+contaminant+detection&rft.au=Jeffrey+Yang%2C+Y%3BGoodrich%2C+JA%3BClark%2C+R+M%3BLi%2C+SY&rft.aulast=Jeffrey+Yang&rft.aufirst=Y&rft.date=2008-03-01&rft.volume=42&rft.issue=6-7&rft.spage=1397&rft.isbn=&rft.btitle=&rft.title=Water+Research&rft.issn=00431354&rft_id=info:doi/10.1016%2Fj.watres.2007.10.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Pipes; Mathematical models; Chlorides; boundary conditions; Sodium; Tracers; Disinfectants; Fluoride; Pesticides; Chlorination; Decay; Contaminants; Drinking water; Drinking Water; Pollutants; Pilot Plants; Slopes; Model Studies DO - http://dx.doi.org/10.1016/j.watres.2007.10.009 ER - TY - JOUR T1 - Indicator Systems AN - 20720434; 8271020 AB - While reviewing a paper submitted for publication in this journal, I was surprised by the fact that it proposed not just a bioindicator, but a bioindicator system, including a monitoring design, a data-retrieval and processing system, and a rudimentary data analysis plan. It was a pleasant surprise because it seems to be the exception in the indicator literature, rather than the rule. This experience brought to mind a discussion with a presenter at the 14 super(th) International Conference on Environmental Bioindicators, who had described what appeared to be an innovative and powerful bioindicator but had no idea how to bring it out of the lab and into the field-monitoring program of her government agency. JF - Environmental Bioindicators AU - Messer, J J AD - National Center for Environmental Assessment, United States Environmental Protection Agency, B-243-01, Research Triangle Park, NC 27711, USA, messer.jay@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 1 EP - 2 VL - 3 IS - 1 SN - 1555-5275, 1555-5275 KW - Ecology Abstracts KW - Data processing KW - Conferences KW - Indicator species KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20720434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Bioindicators&rft.atitle=Indicator+Systems&rft.au=Messer%2C+J+J&rft.aulast=Messer&rft.aufirst=J&rft.date=2008-03-01&rft.volume=3&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Environmental+Bioindicators&rft.issn=15555275&rft_id=info:doi/10.1080%2F15555270801922051 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Data processing; Conferences; Indicator species DO - http://dx.doi.org/10.1080/15555270801922051 ER - TY - JOUR T1 - Use of REMPI-TOFMS for real-time measurement of trace aromatics during operation of aircraft ground equipment AN - 20688312; 8184896 AB - Emissions of aromatic air toxics from aircraft ground equipment (AGE) were measured with a resonance enhanced multiphoton ionization-time of flight mass spectrometry (REMPI-TOFMS) system consisting of a pulsed solid state laser for photoionization and a TOFMS for mass discrimination. This instrument was capable of characterizing turbine emissions and the effect of varying load operations on pollutant production. REMPI-TOFMS is capable of high selectivity and low detection limits (part per trillion to part per billion) in real time (1s resolution). Hazardous air pollutants and criteria pollutants were measured during startups and idle and full load operations. Measurements of compounds such as benzene, toluene, ethylbenzene, xylenes, styrene, and polycyclic aromatic hydrocarbons compared well with standard methods. Startup emissions from the AGE data showed persistent concentrations of pollutants, unlike those from a diesel generator, where a sharp spike in emissions rapidly declined to steady state levels. The time-resolved responses of air toxics concentrations varied significantly by source, complicating efforts to minimize these emissions with common operating prescriptions. The time-resolved measurements showed that pollutant concentrations decline (up to 5x) in a species-specific manner over the course of multiple hours of operation, complicating determination of accurate and precise emission factors via standard extractive sampling. Correlations of air toxic concentrations with more commonly measured pollutants such as CO or PM were poor due to the relatively greater changes in the measured toxics' concentrations. JF - Atmospheric Environment AU - Gullett, B AU - Touati, A AU - Oudejans, L AD - Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, NC 27711, USA, gullett.brian@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 2117 EP - 2128 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 9 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Age KW - Toluene KW - Correlations KW - Mass spectrometry KW - Benzene KW - Atmospheric pollution by diesel engines KW - Aircraft KW - Emission standards KW - Emission measurements KW - Emissions KW - Aircraft engine exhaust emission KW - Polycyclic aromatic hydrocarbons in atmosphere KW - Styrene KW - Atmospheric pollution KW - Aircraft observations KW - Polycyclic aromatic hydrocarbon emissions KW - Air pollution KW - Turbines KW - polycyclic aromatic hydrocarbons KW - Lasers KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20688312?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Use+of+REMPI-TOFMS+for+real-time+measurement+of+trace+aromatics+during+operation+of+aircraft+ground+equipment&rft.au=Gullett%2C+B%3BTouati%2C+A%3BOudejans%2C+L&rft.aulast=Gullett&rft.aufirst=B&rft.date=2008-03-01&rft.volume=42&rft.issue=9&rft.spage=2117&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.11.056 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution by diesel engines; Atmospheric pollution; Aircraft observations; Correlations; Mass spectrometry; Aircraft engine exhaust emission; Lasers; Polycyclic aromatic hydrocarbons in atmosphere; Polycyclic aromatic hydrocarbon emissions; Styrene; Age; Toluene; Benzene; Air pollution; Turbines; Aircraft; Emissions; Emission measurements; Emission standards; polycyclic aromatic hydrocarbons DO - http://dx.doi.org/10.1016/j.atmosenv.2007.11.056 ER - TY - JOUR T1 - Comparison of particulate sulfate and nitrate at collocated CASTNET and IMPROVE sites in the eastern US AN - 20686978; 8184900 AB - Airborne concentration measurements of particulate SO sub(4) super(2) super(-) and NO sub(3) super(-) from two networks, the Clean Air Status and Trends Network (CASTNET) and Interagency Monitoring of PROtected Visual Environments (IMPROVE) Network, are compared at 10 collocated sites in the eastern US for the period 1990 through fall of 2006. CASTNET samples are comprised one nominal 168-h sample per week versus 24-h IMPROVE samples collected twice a week or every third day. To permit comparison, CASTNET and IMPROVE concentration data are matched by week and composed into paired seasonal mean concentration values. CASTNET and IMPROVE seasonal mean SO sub(4) super(2) super(-) and NO sub(3) super(-) concentrations are highly correlated, with respective correlation coefficients of 0.97 and 0.91. Two sites with marine influence display large median relative biases (MRBs) for NO sub(3) super(-) (-42% and -102%) and smaller MRBs for SO sub(4) super(2) super(-) (-14% and -17%), indicating seasonal mean CASTNET concentrations to be biased higher than corresponding collocated values from IMPROVE at these two sites. Statistically significant median biases (MBs) and MRBs are present for comparisons of seasonal mean CASTNET and IMPROVE SO sub(4) super(2) super(-) concentrations, indicating seasonal mean CASTNET SO sub(4) super(2) super(-) concentrations to be biased 4-7% higher than collocated values from IMPROVE. Larger and more variable MRBs are present for comparisons of seasonal mean CASTNET and IMPROVE NO sub(3) super(-) concentrations. For the 10 collocated sites considered in the current study, MRBs between site-specific seasonal mean CASTNET and IMPROVE NO sub(3) super(-) concentrations range between 39% and -102%, and between 39% and -25% when marine sites are excluded. For the ensemble of all paired sites, the summertime MRB of 44% indicates that CASTNET NO sub(3) super(-) concentrations are biased low, consistent with volatilization losses of particulate NO sub(3) super(-) in the CASTNET sampler at high temperatures and low ambient NO sub(3) super(-) concentrations that are typical during summer. These results should be considered prior to combining data from the CASTNET and IMPROVE (and possibly Chemical Speciation Network, CSN) networks for obtaining more aerially comprehensive representations of the atmosphere or for comparison with air quality model predictions. Biases in particulate SO sub(4) super(2) super(-) and NO sub(3) super(-) concentrations from collocated CASTNET and IMPROVE sites are likely due in part to differences in the configurations of the samplers employed by the two networks (e.g., presence or absence of size-selective inlets). JF - Atmospheric Environment AU - Sickles, JE AU - Shadwick, D S AD - ORD, NERL, Research Triangle Park, NC 27711, USA, sickles.joseph@epa.gov Y1 - 2008/03// PY - 2008 DA - March 2008 SP - 2062 EP - 2073 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 42 IS - 9 SN - 1352-2310, 1352-2310 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Pollution Abstracts; Oceanic Abstracts; Meteorological & Geoastrophysical Abstracts KW - Sulfates KW - Chemical composition KW - Nitrates KW - Statistical analysis KW - Correlations KW - Air quality KW - Particulates KW - Atmosphere KW - Air quality models KW - USA KW - High temperatures KW - Sulfur dioxide KW - Chemical speciation KW - Atmospheric chemistry KW - summer KW - Coastal inlets KW - Seasonal variations KW - high temperature KW - Q2 09188:Atmospheric chemistry KW - P 0000:AIR POLLUTION KW - M2 551.5:General (551.5) KW - O 2050:Chemical Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20686978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Comparison+of+particulate+sulfate+and+nitrate+at+collocated+CASTNET+and+IMPROVE+sites+in+the+eastern+US&rft.au=Sickles%2C+JE%3BShadwick%2C+D+S&rft.aulast=Sickles&rft.aufirst=JE&rft.date=2008-03-01&rft.volume=42&rft.issue=9&rft.spage=2062&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.11.051 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Chemical composition; Nitrates; Chemical speciation; Atmospheric chemistry; Coastal inlets; Particulates; High temperatures; Correlations; Statistical analysis; Air quality models; Sulfates; Sulfur dioxide; summer; Air quality; Atmosphere; Seasonal variations; high temperature; USA DO - http://dx.doi.org/10.1016/j.atmosenv.2007.11.051 ER - TY - JOUR T1 - Indoor and outdoor concentrations of organic and inorganic molecular markers: Source apportionment of PM sub(2) sub(.) sub(5) using low-volume samples AN - 20686948; 8184690 AB - Concentrations of PM sub(2) sub(.) sub(5), elemental carbon (EC), organic carbon (OC), 30 organic source markers (13 alkanes, 14 polycyclic aromatic hydrocarbons and ketones, and 3 hopanes) and 19 inorganic source markers are reported from residential indoor, residential outdoor, and ambient microenvironments from a nine home pilot study conducted in Tampa, Florida. Mean daily PM sub(2) sub(.) sub(5) concentrations were 9.3 mu gm super(-) super(3) for residential indoor, 11.3 mu gm super(-) super(3) for residential outdoor, and 12.7 mu gm super(-) super(3) for ambient microenvironments. The EPA Chemical Mass Balance Model (CMB8.2) was used for source apportionment of PM sub(2) sub(.) sub(5) residential outdoor samples. Four main sources of PM sub(2) sub(.) sub(5) were identified: sulfate (55+/-6%) (average outdoor PM sub(2) sub(.) sub(5)+/-S.D.), gasoline-powered motor vehicles (32+/-4%), diesel-powered vehicles (8+/-2%), and road dust (5+/-1%). JF - Atmospheric Environment AU - Olson, DA AU - Turlington, J AU - Duvall, R M AU - McDow AU - Stevens, C D AU - Williams, R AD - United States Environmental Protection Agency, Research Triangle Park, NC 27711, USA, olson.david@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 1742 EP - 1751 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 8 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Sulfates KW - Atmospheric pollution models KW - Motor vehicles KW - Organic carbon KW - Dust KW - Carbon KW - Polycyclic aromatic hydrocarbons in indoor air KW - Atmospheric chemistry models KW - Polycyclic aromatic hydrocarbons in atmosphere KW - Particulate matter in indoor air KW - Particle size KW - Atmospheric pollution KW - USA, Florida, Tampa KW - Atmospheric pollution by motor vehicles KW - EPA KW - Ketones KW - microenvironments KW - Residential areas KW - polycyclic aromatic hydrocarbons KW - Indoor environments KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20686948?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Indoor+and+outdoor+concentrations+of+organic+and+inorganic+molecular+markers%3A+Source+apportionment+of+PM+sub%282%29+sub%28.%29+sub%285%29+using+low-volume+samples&rft.au=Olson%2C+DA%3BTurlington%2C+J%3BDuvall%2C+R+M%3BMcDow%3BStevens%2C+C+D%3BWilliams%2C+R&rft.aulast=Olson&rft.aufirst=DA&rft.date=2008-03-01&rft.volume=42&rft.issue=8&rft.spage=1742&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.11.035 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution models; Polycyclic aromatic hydrocarbons in indoor air; Atmospheric pollution; Atmospheric chemistry models; Polycyclic aromatic hydrocarbons in atmosphere; Atmospheric pollution by motor vehicles; Particulate matter in indoor air; Sulfates; Particle size; EPA; Ketones; Carbon; microenvironments; Motor vehicles; Organic carbon; Residential areas; polycyclic aromatic hydrocarbons; Indoor environments; Dust; USA, Florida, Tampa DO - http://dx.doi.org/10.1016/j.atmosenv.2007.11.035 ER - TY - JOUR T1 - Topology matters: Network topology affects outcomes from community ecology neutral models AN - 20658625; 8102458 AB - Topology affects outcomes of processes in planar networks. Hexagon tessellations have different performance than, and are often superior to, square tessellations in applications such as fluid dynamics, percolation theory, self-avoiding walks, survey sample design, and quantization. Hexagon tessellations and square tessellations using both von Neumann and Moore neighborhoods were examined as a network topology for neutral ecology community models, following the simulation approach of Graham Bell. These models, which assume identical life history and movement properties for each individual of each species, produce collective properties of communities, such as abundance distributions, range distributions, spatial variation in abundance, species-area curves, and spatial variation in species composition, that match many empirical patterns. The simulations in this study varied the dispersal rate but kept birth, death, and immigration rates constant. For these experiments, ending community populations, species richness, Shannon diversity, and Simpson diversity were clearly different for the different topologies, but the relationship between the topologies varied as the dispersal rate changed. Empirical distributions of the performance measures also showed clear differences among topologies. The interaction of topology with dispersal, spatial boundary effects, and other parameters of these models appears to be quite complex and warrants further research. JF - Computers, Environment and Urban Systems AU - White, D AU - Kiester, A R AD - 200 SW 35th Street, Corvallis, OR 97333, USA, white.denis@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 165 EP - 171 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 32 IS - 2 SN - 0198-9715, 0198-9715 KW - Sustainability Science Abstracts KW - Mortality KW - Immigration KW - life history KW - Simulation KW - fluid dynamics KW - dispersal KW - Ecology KW - spatial distribution KW - species richness KW - abundance KW - Urban areas KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20658625?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Computers%2C+Environment+and+Urban+Systems&rft.atitle=Topology+matters%3A+Network+topology+affects+outcomes+from+community+ecology+neutral+models&rft.au=White%2C+D%3BKiester%2C+A+R&rft.aulast=White&rft.aufirst=D&rft.date=2008-03-01&rft.volume=32&rft.issue=2&rft.spage=165&rft.isbn=&rft.btitle=&rft.title=Computers%2C+Environment+and+Urban+Systems&rft.issn=01989715&rft_id=info:doi/10.1016%2Fj.compenvurbsys.2007.11.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Ecology; Mortality; spatial distribution; Immigration; species richness; life history; Simulation; fluid dynamics; dispersal; Urban areas; abundance DO - http://dx.doi.org/10.1016/j.compenvurbsys.2007.11.002 ER - TY - JOUR T1 - Pyrethroid modulation of spontaneous neuronal excitability and neurotransmission in hippocampal neurons in culture AN - 20655011; 8103378 AB - Pyrethroid insecticides have potent actions on voltage-gated sodium channels (VGSC), inhibiting inactivation and increasing channel open times. These are thought to underlie, at least in part, the clinical symptoms of pyrethroid intoxication. However, disruption of neuronal activity at higher levels of organization is less well understood. In order to characterize pyrethroid effects on neurotransmitter release and neuronal excitability in glutamatergic networks, we examined the effects of deltamethrin (DM) and permethrin (PM) on neuronal activity in hippocampal neuronal cultures using patch-clamp and microelectrode array (MEA) recordings. In the presence of inhibitors of GABA receptors, spontaneous excitatory post-synaptic currents (sEPSCs) and spontaneous spike rates were reduced in a concentration-dependent manner by both DM and PM. IC sub(5) sub(0) values were 0.037 and 0.70 mu M for inhibition of sEPSCs and 0.60 and 21.8 mu M for inhibition of spontaneous spike rate by DM and PM, respectively. Both compounds altered burst activity by decreasing the number of spikes during spontaneous bursting, the number of sEPSCs within a bursting release event and the duration of sEPSC bursts while increasing both the interspike interval and the time between sEPSCs. Exposure of neurons to the VGSC-specific modulator veratridine had effects similar to both DM and PM, while inhibition of voltage-gated calcium channels had no effect on spontaneous spike rates. In the absence of GABA receptor antagonists, both DM and PM increased spontaneous spike rates. Altogether, these data demonstrate that DM and PM disrupt network activity in vitro, largely via a VGSC-dependent mechanism. JF - Neurotoxicology AU - Meyer, DA AU - Carter, J M AU - Johnstone, AFM AU - Shafer, T J AD - MD B105-05, NHEERL, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, United States, shafer.tim@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 213 EP - 225 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 29 IS - 2 SN - 0161-813X, 0161-813X KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - Intoxication KW - Sodium channels (voltage-gated) KW - Hippocampus KW - Permethrin KW - Cell culture KW - Calcium channels (voltage-gated) KW - Excitability KW - Firing pattern KW - Deltamethrin KW - Antagonists KW - gamma -Aminobutyric acid receptors KW - Neuromodulation KW - Firing rate KW - Glutamatergic transmission KW - Insecticides KW - Neurotransmission KW - veratridine KW - Neurons KW - Pyrethroids KW - Neurotransmitter release KW - Microelectrodes KW - N3 11028:Neuropharmacology & toxicology KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20655011?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Pyrethroid+modulation+of+spontaneous+neuronal+excitability+and+neurotransmission+in+hippocampal+neurons+in+culture&rft.au=Meyer%2C+DA%3BCarter%2C+J+M%3BJohnstone%2C+AFM%3BShafer%2C+T+J&rft.aulast=Meyer&rft.aufirst=DA&rft.date=2008-03-01&rft.volume=29&rft.issue=2&rft.spage=213&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/10.1016%2Fj.neuro.2007.11.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Intoxication; Sodium channels (voltage-gated); Hippocampus; Permethrin; Cell culture; Calcium channels (voltage-gated); Excitability; Firing pattern; Antagonists; Deltamethrin; gamma -Aminobutyric acid receptors; Glutamatergic transmission; Firing rate; Neuromodulation; Insecticides; Neurotransmission; veratridine; Neurons; Pyrethroids; Neurotransmitter release; Microelectrodes DO - http://dx.doi.org/10.1016/j.neuro.2007.11.005 ER - TY - JOUR T1 - The Effect of Ambient Air Pollution during Early Pregnancy on Fetal Ultrasonic Measurements during Mid-Pregnancy AN - 20601422; 8113094 AB - Background: Over the past decade there has been mounting evidence that ambient air pollution during pregnancy influences fetal growth. Objectives: This study was designed to examine possible associations between fetal ultrasonic measurements collected from 15.623 scans (13-26 weeks gestation) and ambient air pollution during early pregnancy. Methods: We calculated mothers' average monthly exposures over the first 4 months of pregnancy for the following pollutants: paniculate matter < 10 mu m aerodynamic diameter (PM sub(10)), ozone, nitrogen dioxide, and sulfur dioxide. We examined associations with fetal femur length (FL), biparietal diameter (BPD), head circumference (HC), and abdominal circumference (AC). Final analyses included scans from only those women within 2 km of an air pollution monitoring site. We controlled for long-term trend, season, temperature, gestation, mother's age, socioeconomic status, and fetal sex. Results: A reduction in fetal AC was associated with O sub(3) during days 31-60 [-1.42 mm; 95% confidence interval (CI), -2.74 to -0.09], SO sub(2) during days 61-90 (-1.67 mm; 95% CI, -2.94 to -0.40), and PM sub(10) during days 91-120 (-0.78 mm; 95% CI, -1.49 to -0.08). Other results showed a reduction in BPD (-0.68 mm; 95% CI, -1.09 to -0.27) associated with SO sub(2) during days 0-30, a reduction in HC (-1.02 mm; 95% CI, -1.78 to -0.26) associated with PM sub(10) during days 91-120, and a reduction in FL associated with PM sub(10) during days 0-30 (-0.28 mm; 95% CI, -0.48 to -0.08) and 91-120 (-0.23; 95% CI, -0.42 to -0.04). Conclusion: We found strong effects of ambient air pollution on ultrasound measures. Future research, including more individually detailed data, is needed to confirm our results. JF - Environmental Health Perspectives AU - Hansen, CA AU - Barnett, A G AU - Pritchard, G AD - National Center for Environmental Assessment, U.S. Environmental Protection Agency, Mail Drop B243-01, Research Triangle Park, NC 27711, USA, Hansen.Craig@epamail.epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 362 EP - 369 VL - 116 IS - 3 SN - 0091-6765, 0091-6765 KW - Health & Safety Science Abstracts; Pollution Abstracts; Toxicology Abstracts KW - Pollution monitoring KW - Age KW - Socioeconomics KW - Pollution effects KW - Femur KW - Nitrogen dioxide KW - Sulfur dioxide KW - Pollutants KW - Aerodynamics KW - Gestation KW - Ultrasound KW - Adenylate cyclase KW - Ozone KW - Temperature effects KW - Temperature KW - Fetuses KW - Pregnancy KW - Air pollution KW - Socio-economic aspects KW - Ultrasonics KW - X 24490:Other KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20601422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=The+Effect+of+Ambient+Air+Pollution+during+Early+Pregnancy+on+Fetal+Ultrasonic+Measurements+during+Mid-Pregnancy&rft.au=Hansen%2C+CA%3BBarnett%2C+A+G%3BPritchard%2C+G&rft.aulast=Hansen&rft.aufirst=CA&rft.date=2008-03-01&rft.volume=116&rft.issue=3&rft.spage=362&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.10720 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Age; Femur; Fetuses; Pregnancy; Air pollution; Nitrogen dioxide; Socio-economic aspects; Sulfur dioxide; Pollutants; Ultrasonics; Gestation; Ultrasound; Ozone; Adenylate cyclase; Pollution monitoring; Aerodynamics; Temperature; Pollution effects; Socioeconomics DO - http://dx.doi.org/10.1289/ehp.10720 ER - TY - JOUR T1 - Identification of regime shifts in time series using neighborhood statistics AN - 20597329; 8096109 AB - Sudden and significant changes in biotic and abiotic variables have been observed across a variety of systems. The identification of such regime shifts in time series includes both model-fitting and statistical approaches. We introduce two methods that use state- or measurement-space neighborhood statistics to pick out regime shifts. Analysis of simulated and real data sets shows that these methods can be an effective means of identifying regime shifts for single variable as well as multivariable time series. In addition, these methods can be used on systems with non-equilibrium steady states. However, care must be taken in interpreting results as these methods do respond to changes in time series that are not consistent with the regime shift concept. JF - Ecological Complexity AU - Pawlowski, C W AU - Cabezas, H AD - 26 W. Martin Luther King Dr., Cincinnati, OH 45268, United States, cabezas.heriberto@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 30 EP - 36 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 5 IS - 1 SN - 1476-945X, 1476-945X KW - Ecology Abstracts KW - Mathematical models KW - Statistical analysis KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20597329?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Complexity&rft.atitle=Identification+of+regime+shifts+in+time+series+using+neighborhood+statistics&rft.au=Pawlowski%2C+C+W%3BCabezas%2C+H&rft.aulast=Pawlowski&rft.aufirst=C&rft.date=2008-03-01&rft.volume=5&rft.issue=1&rft.spage=30&rft.isbn=&rft.btitle=&rft.title=Ecological+Complexity&rft.issn=1476945X&rft_id=info:doi/10.1016%2Fj.ecocom.2007.07.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Statistical analysis; Mathematical models DO - http://dx.doi.org/10.1016/j.ecocom.2007.07.005 ER - TY - JOUR T1 - Perfluoroalkyl Acids and Related Chemistries-Toxicokinetics and Modes of Action AN - 20565121; 8043228 AB - The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are important chemicals that have numerous consumer and industrial applications. However, recent discoveries that some of these compounds have global distribution, environmental persistence, presence in humans and wildlife, as well as toxicity in laboratory animal models, have generated considerable scientific, regulatory, and public interest on an international scale. The Society of Toxicology Contemporary Concepts in Toxicology Symposium, entitled "Perfluoroalkyl Acids and Related Chemistries: Toxicokinetics and Modes-of-Action Workshop" was held February 14-16, 2007 at the Westin Arlington Gateway, Arlington, VA. In addition to the Society of Toxicology, this symposium was sponsored by 3M Company, DuPont, Plastics Europe, and the U.S. Environmental Protection Agency. The objectives of this 3-day meeting were to (1) provide an overview of PFAA toxicity and description of recent findings with the sulfonates, carboxylates, and telomer alcohols; (2) address the toxicokinetic profiles of various PFAAs among animal models and humans, and the biological processes that are responsible for these observations; (3) examine the possible modes of action that determine the PFAA toxicities observed in animal models, and their relevance to human health risks; and (4) identify the critical research needs and strategies to fill the existing informational gaps that hamper risk assessment of these chemicals. This report summarizes the discourse that occurred during the symposium. JF - Toxicological Sciences AU - Andersen, Melvin E AU - Butenhoff, John L AU - Chang, Shu-Ching AU - Farrar, David G AU - Kennedy, Gerald LJr AU - Lau, Christopher AU - Olsen, Geary W AU - Seed, Jennifer AU - Wallace, Kendall B AD - The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709. Medical Department, 3M Company, St. Paul, Minnesota 55144. IneosChlor, Manchester, UK. DuPont Haskell Laboratories, DuPont, Newark, Delaware 19714. Reproduction Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711. Risk Assessment Division, Office of Pollution Prevention and Toxics, U.S. Environmental Protection Agency, Washington, DC 20460. Department of Biochemistry and Molecular Biology, School of Medicine, University of Minnesota, Duluth, Minnesota 55812 Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 3 EP - 14 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 102 IS - 1 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Risk assessment KW - Conferences KW - Wildlife KW - Laboratory animals KW - Animal models KW - Toxicity KW - Salts KW - Industrial applications KW - Reviews KW - Acids KW - alcohols KW - Consumers KW - Plastics KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20565121?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Perfluoroalkyl+Acids+and+Related+Chemistries-Toxicokinetics+and+Modes+of+Action&rft.au=Andersen%2C+Melvin+E%3BButenhoff%2C+John+L%3BChang%2C+Shu-Ching%3BFarrar%2C+David+G%3BKennedy%2C+Gerald+LJr%3BLau%2C+Christopher%3BOlsen%2C+Geary+W%3BSeed%2C+Jennifer%3BWallace%2C+Kendall+B&rft.aulast=Andersen&rft.aufirst=Melvin&rft.date=2008-03-01&rft.volume=102&rft.issue=1&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Conferences; Wildlife; Animal models; Laboratory animals; Toxicity; Salts; Industrial applications; Acids; Reviews; alcohols; Consumers; Plastics ER - TY - JOUR T1 - Environmental Technology Verification (ETV) test of dioxin emission monitors AN - 19901105; 8638341 AB - The performance of four dioxin emission monitors, including two long-term sampling devices, the Dioxin-MonitoringSystem (DMS) and AMESA (the adsorption method for sampling dioxins and furans), and two semireal-time continuous monitors, the resonance ionization with multimirror photon accumulation time- of-flight mass spectrometer (RIMMPA-TOFMS) and the jet resonance-enhanced multiphoton ionization (jet-REMPI) system were tested. A package boiler burning a simulated chlorinated hazardous waste was used for a total of nine tests. Reference samples were collected during each test and analyzed for polychlorinated dibenzodioxins and dibenzofurans (PCDDs/Fs) using gas chromatography mass spectrometry. The PCDD/F concentrations of the reference samples measured by EPA Method 23 ranged from 0.9 to 6.0 ng toxic equivalence (TEQ)/dry standard cubic meter. The relative accuracies achieved by DMS, AMESA, and jet-REMPI varied from 22.6% to 78.2%, with 100% data completeness. The RIMMPA-TOFMS produced no quantifiable results due to various difficulties associated with the instrument during the testing. The two long-term samplers were easy to install and operate and provided a cumulative, averaged emission for the sampling period. The operations of the two semi-real-time continuous monitors were relatively complex, but one of them provided on-site, real-time data for PCDD/F emissions from measurement of a TEQ correlative indicator compound. This article summarizes results from the individual Environmental Technology Verification reports for the four dioxin monitors. JF - Journal of Material Cycles and Waste Management AU - Lee, Chun Wai AU - Tabor, Dennis G AU - Cowen, Kenneth A AD - Air Pollution Prevention and Control Division (E305-01), National Risk Management Research Laboratory, Office of Research and Development, United States Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, NC 27711, USA, lee.chun-wai@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 38 EP - 45 PB - Springer-Verlag, 3-13 Hongo 3-chrome, Bunkyo-ku Tokyo 113-0033 Japan, [URL:http://www.springerlink.com] VL - 10 IS - 1 SN - 1438-4957, 1438-4957 KW - Toxicology Abstracts; Pollution Abstracts KW - Continuous emission monitor KW - Dioxins KW - PCDDs/Fs KW - POPs KW - Incineration emissions This work was presented KW - in part KW - at the Fourth International Conference on Combustion KW - Incineration/Pyrolysis and Emission Control (i-CIPEC) KW - polychlorinated dibenzodioxins KW - Photons KW - Mass spectrometry KW - Mass spectroscopy KW - Waste management KW - Gas chromatography KW - Emissions KW - Sampling KW - PCDD KW - Packaging KW - Data processing KW - Boilers KW - burning KW - Furans KW - Samplers KW - EPA KW - Dibenzofuran KW - Adsorption KW - Burning KW - Ionization KW - Hazardous wastes KW - Dioxin KW - Technology KW - P 0000:AIR POLLUTION KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19901105?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Material+Cycles+and+Waste+Management&rft.atitle=Environmental+Technology+Verification+%28ETV%29+test+of+dioxin+emission+monitors&rft.au=Lee%2C+Chun+Wai%3BTabor%2C+Dennis+G%3BCowen%2C+Kenneth+A&rft.aulast=Lee&rft.aufirst=Chun&rft.date=2008-03-01&rft.volume=10&rft.issue=1&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Journal+of+Material+Cycles+and+Waste+Management&rft.issn=14384957&rft_id=info:doi/10.1007%2Fs10163-007-0196-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - polychlorinated dibenzodioxins; Data processing; Photons; Furans; Samplers; Mass spectroscopy; Dibenzofuran; Gas chromatography; Adsorption; Sampling; Burning; Ionization; Dioxin; Mass spectrometry; Boilers; burning; Dioxins; Waste management; EPA; Emissions; PCDD; Hazardous wastes; Technology; Packaging DO - http://dx.doi.org/10.1007/s10163-007-0196-7 ER - TY - JOUR T1 - Assessing Habitat Quality of Mount Hope Bay and Narragansett Bay Using Growth, RNA:DNA, and Feeding Habits of Caged Juvenile Winter Flounder (Pseudopleuronectes americanus Walbaum) AN - 19691174; 8704478 AB - Somatic growth rates, RNA:DNA, and feeding habits of juvenile Pseudopleuronectes americanus (Winter Flounder) were used to asses small-scale spatio-temporal variations in the habitat quality of Mount Hope Bay and Narragan-sett Bay, RI. Three successive caging experiments (14-16 d each) were conducted with flounder (initial size = 25-35 mm total length) in June and July 2003 in shallow water habitats (20 degree C. Benthic core samples indicated that food availability was greatest at Spar Island and was attributable to the numerical dominance of Crepidula fornicata Linnaeus (slipper limpet) during the early summer. Moreover, stomach contents of flounder reflected differences in prey species composition, whereby individuals from Spar Island consumed a higher percentage of molluscs relative to the other sites, where the preferred prey items were harpacticoid copepods and small decapods (primarily brachyuran crabs). Despite the observed discrepancies in feeding habits across sites, the extent of stomach fullness for flounder did not vary spatially (mean fullness = 44-49% across sites). It is concluded that the somatic growth, RNA:DNA, and feeding behavior of juvenile flounder in Mount Hope Bay and Narragansett Bay varies significantly across small spatio-temporal scales in response to changes in dissolved oxygen and thermal conditions. JF - Northeastern Naturalist AU - Meng, Lesa AU - Taylor, David L AU - Serbst, Jonathan AU - Powell, JChristopher AD - 1US Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Laboratory, Atlantic Ecology Division, 27 Tarzwell Drive, Narragansett, RI 02882. Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 35 EP - 56 PB - Allen Press, Inc., 810 East Tenth St. VL - 15 IS - 1 SN - 1092-6194, 1092-6194 KW - Ecology Abstracts; ASFA Aquaculture Abstracts; Biochemistry Abstracts 2: Nucleic Acids; ASFA 1: Biological Sciences & Living Resources KW - Food organisms KW - PSW, Antarctica, Antarctic Peninsula, Graham Land, Hope Bay KW - ANW, USA, Virginia, Hog I. KW - Food availability KW - Dissolved oxygen KW - Marine fish KW - Islands KW - Feeding behaviour KW - Pseudopleuronectes americanus KW - Copepoda KW - Species composition KW - Mollusca KW - Feeding behavior KW - Prey KW - Temperature effects KW - Growth rate KW - Marine KW - Feeding KW - Decapoda KW - Pleuronectiformes KW - Crepidula fornicata KW - Water temperature KW - Habitat KW - Dominance KW - Stomach content KW - Community composition KW - Hypoxia KW - ANW, USA, Rhode Island, Narragansett Bay KW - Marine molluscs KW - Stomach KW - Q3 08583:Shellfish culture KW - Q1 08583:Shellfish culture KW - D 04040:Ecosystem and Ecology Studies KW - N 14845:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19691174?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Northeastern+Naturalist&rft.atitle=Assessing+Habitat+Quality+of+Mount+Hope+Bay+and+Narragansett+Bay+Using+Growth%2C+RNA%3ADNA%2C+and+Feeding+Habits+of+Caged+Juvenile+Winter+Flounder+%28Pseudopleuronectes+americanus+Walbaum%29&rft.au=Meng%2C+Lesa%3BTaylor%2C+David+L%3BSerbst%2C+Jonathan%3BPowell%2C+JChristopher&rft.aulast=Meng&rft.aufirst=Lesa&rft.date=2008-03-01&rft.volume=15&rft.issue=1&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=Northeastern+Naturalist&rft.issn=10926194&rft_id=info:doi/10.1656%2F1092-6194%282008%29152.0.CO%3B2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Growth rate; Temperature effects; Marine fish; Stomach content; Food organisms; Community composition; Feeding behaviour; Marine molluscs; Dissolved oxygen; Feeding; Food availability; Water temperature; Habitat; Dominance; Islands; Hypoxia; Species composition; Feeding behavior; Prey; Stomach; Pleuronectiformes; Decapoda; Crepidula fornicata; Pseudopleuronectes americanus; Copepoda; Mollusca; PSW, Antarctica, Antarctic Peninsula, Graham Land, Hope Bay; ANW, USA, Virginia, Hog I.; ANW, USA, Rhode Island, Narragansett Bay; Marine DO - http://dx.doi.org/10.1656/1092-6194(2008)15[35:AHQOMH]2.0.CO;2 ER - TY - JOUR T1 - Verification results of jet resonance-enhanced multiphoton ionization as a real-time PCDD/F emission monitor AN - 19552554; 8638342 AB - A jet resonance-enhanced multiphoton ionization (REMPI) monitor was tested on a hazardous-waste-fired boiler for its ability to determine concentrations of polychlorinated dibenzodioxins and dibenzofurans (PCDDs/Fs). Jet REMPI is a real-time instrument capable of highly selective and sensitive (from parts per billion to parts per trillion) detection of a broad range of aromatic compounds, including a number of air toxic compounds. The PCDD/F toxic equivalency (TEQ) value was derived from a predetermined correlation (R super(2) = 0.74) with monochlorobenzene (MClBz). This relationship was applied to nine subsequent jet REMPI on-line measurements of MClBz and parallel, standard extractive sampling for PCDD/F TEQ. For high waste-firing rates, with a range of PCDD/F TEQ values between 3.9 and 6.0 ng TEQ/m super(3), the TEQ values predicted by jet REMPI had a relative difference of 26% with the standard EPA Method 23 results. At low waste-firing rates (0.9-1.6 ng TEQ/m super(3)), the relative difference increased to 219%. This limited testing shows that jet REMPI has promise as an on-line diagnostic monitor, providing feedback on the effects on PCDD/F emissions of operating parameter changes such as fuel feed interruptions or air pollution control failures. JF - Journal of Material Cycles and Waste Management AU - Gullett, Brian AU - Oudejans, Lukas AU - Touati, Abderrahmane AU - Ryan, Shawn AU - Tabor, Dennis AD - U.S. Environmental Protection Agency (E305-01), Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, NC 27711, USA, gullett.brian@epa.gov Y1 - 2008/03// PY - 2008 DA - Mar 2008 SP - 32 EP - 37 PB - Springer-Verlag, 3-13 Hongo 3-chrome, Bunkyo-ku Tokyo 113-0033 Japan, [URL:http://www.springerlink.com] VL - 10 IS - 1 SN - 1438-4957, 1438-4957 KW - Pollution Abstracts KW - Air pollution control KW - Boilers KW - EPA KW - Aromatic compounds KW - Emissions KW - PCDD KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19552554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Material+Cycles+and+Waste+Management&rft.atitle=Verification+results+of+jet+resonance-enhanced+multiphoton+ionization+as+a+real-time+PCDD%2FF+emission+monitor&rft.au=Gullett%2C+Brian%3BOudejans%2C+Lukas%3BTouati%2C+Abderrahmane%3BRyan%2C+Shawn%3BTabor%2C+Dennis&rft.aulast=Gullett&rft.aufirst=Brian&rft.date=2008-03-01&rft.volume=10&rft.issue=1&rft.spage=32&rft.isbn=&rft.btitle=&rft.title=Journal+of+Material+Cycles+and+Waste+Management&rft.issn=14384957&rft_id=info:doi/10.1007%2Fs10163-007-0195-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - EPA; Aromatic compounds; Emissions; Air pollution control; Boilers; PCDD DO - http://dx.doi.org/10.1007/s10163-007-0195-8 ER - TY - JOUR T1 - Thermoregulation and its influence on toxicity assessment. AN - 70356356; 18096291 AB - The thermoregulatory system of laboratory rodents is susceptible to a variety of chemical toxicants. Because temperature directly affects the reaction of virtually all biological processes, it is critical to consider how changes in the thermoregulatory response to a toxicant may affect physiological, behavioral, and pathological endpoints. Researchers in industry and government laboratories are often faced with addressing how changes in body temperature of their experimental subjects may affect the outcome of a particular toxicity test and/or screening panel. However, many toxicologists are either unaware of the importance or ignore the potential impact of a toxic-induced change in body temperature. This paper endeavors to summarize the importance of thermoregulation in the study of toxicology and propose recommendations for thermometry that researchers may utilize in their toxicological studies. JF - Toxicology AU - Gordon, Christopher J AU - Spencer, Pamela J AU - Hotchkiss, Jon AU - Miller, Diane B AU - Hinderliter, Paul M AU - Pauluhn, Juergen AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, B105-04, U.S. Environmental Protection Agency, 109 S.T.W. Alexander Drive, Research Triangle Park, NC 27711, USA. gordon.christopher@epa.gov Y1 - 2008/02/28/ PY - 2008 DA - 2008 Feb 28 SP - 87 EP - 97 VL - 244 IS - 2-3 SN - 0300-483X, 0300-483X KW - Index Medicus KW - Animals, Newborn KW - Animals KW - Hypothermia -- physiopathology KW - Humans KW - Thermometers KW - Hypothermia -- chemically induced KW - Body Temperature Regulation -- drug effects KW - Body Temperature Regulation -- physiology KW - Toxicity Tests UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70356356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Thermoregulation+and+its+influence+on+toxicity+assessment.&rft.au=Gordon%2C+Christopher+J%3BSpencer%2C+Pamela+J%3BHotchkiss%2C+Jon%3BMiller%2C+Diane+B%3BHinderliter%2C+Paul+M%3BPauluhn%2C+Juergen&rft.aulast=Gordon&rft.aufirst=Christopher&rft.date=2008-02-28&rft.volume=244&rft.issue=2-3&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-09 N1 - Date created - 2008-03-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Chlorpyrifos transformation by aqueous chlorine in the presence of bromide and natural organic matter. AN - 70319012; 18237132 AB - The aqueous chlorination of chlorpyrifos (CP) was investigated in the presence of bromide and natural organic matter (NOM), which were identified as naturally occurring aqueous constituents that could affect CP transformation rates to the toxic product chlorpyrifos oxon (CPO). Bromide can be oxidized by chlorine to form hypobromous acid (HOBr), which was found to oxidize CP at a rate that was 3 orders of magnitude faster than was the case with chlorine: k HOBr,CP=1.14 (+/-0.21)x10(9) M(-1) h(-1) and k HOCl,CP=1.72x10(6) M(-1) h(-1), respectively. Similar to previous findings with the hypochlorite ion, hypobromite (OBr-) was found to accelerate the hydrolysis of CP and CPO: kOBr,CP=965 (+/-110) M(-1) h(-1) and kOBr,CPO=1390 (+/-160) M(-1) h(-1), respectively. Treated water from the Athens-Clarke County (ACC) water treatment plant in Athens, GA, was used in some of the experiments as a NOM source. A mechanistic model was used to adequately predict the loss of CP as well as the formation of CPO and the hydrolysis product 3,5,6-trichloro-2-pyridinol (TCP) in the presence of the ACC water. JF - Journal of agricultural and food chemistry AU - Duirk, Stephen E AU - Tarr, J Christopher AU - Collette, Timothy W AD - Office of Research and Development, National Exposure Research Laboratory, U.S. Environmental Protection AGency, Athens, GA 30605, USA. duirk.stephen@epa.gov Y1 - 2008/02/27/ PY - 2008 DA - 2008 Feb 27 SP - 1328 EP - 1335 VL - 56 IS - 4 SN - 0021-8561, 0021-8561 KW - Bromides KW - 0 KW - Insecticides KW - Solutions KW - Water KW - 059QF0KO0R KW - Chlorine KW - 4R7X1O2820 KW - Chlorpyrifos KW - JCS58I644W KW - Index Medicus KW - Oxidation-Reduction KW - Kinetics KW - Water -- chemistry KW - Hydrolysis KW - Insecticides -- metabolism KW - Chlorpyrifos -- chemistry KW - Bromides -- chemistry KW - Insecticides -- chemistry KW - Models, Chemical KW - Chlorine -- chemistry KW - Chlorpyrifos -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70319012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Chlorpyrifos+transformation+by+aqueous+chlorine+in+the+presence+of+bromide+and+natural+organic+matter.&rft.au=Duirk%2C+Stephen+E%3BTarr%2C+J+Christopher%3BCollette%2C+Timothy+W&rft.aulast=Duirk&rft.aufirst=Stephen&rft.date=2008-02-27&rft.volume=56&rft.issue=4&rft.spage=1328&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/10.1021%2Fjf072468s LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-18 N1 - Date created - 2008-02-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1021/jf072468s ER - TY - CPAPER T1 - Evaluation of the Differential Method for PM10- 2.5 Mass Concentration Measurement T2 - 7th International Symposium on Advanced Environmental Monitoring (ISAEM 2008) AN - 40788738; 4789128 DE: JF - 7th International Symposium on Advanced Environmental Monitoring (ISAEM 2008) AU - Chen, Fu-Lin AU - Vanderpool, Robert AU - Williams, Ronald AU - Dimmick, Fred Y1 - 2008/02/25/ PY - 2008 DA - 2008 Feb 25 KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40788738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=7th+International+Symposium+on+Advanced+Environmental+Monitoring+%28ISAEM+2008%29&rft.atitle=Evaluation+of+the+Differential+Method+for+PM10-+2.5+Mass+Concentration+Measurement&rft.au=Chen%2C+Fu-Lin%3BVanderpool%2C+Robert%3BWilliams%2C+Ronald%3BDimmick%2C+Fred&rft.aulast=Chen&rft.aufirst=Fu-Lin&rft.date=2008-02-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=7th+International+Symposium+on+Advanced+Environmental+Monitoring+%28ISAEM+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://ademrc.org/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The U.S. EPAs Support for Environmental Rapid Risk Assessment (SERRA) Database and its Application to Biothreat DoseResponse Data T2 - 6th Annual ASM Biodefense and Emerging Diseases Research Meeting AN - 40828473; 4809090 JF - 6th Annual ASM Biodefense and Emerging Diseases Research Meeting AU - Taft, S AU - Nichols, T AU - Baumel, I AU - Hines, S AU - Taylor, M AU - SonichMullin, C AU - McKean, D Y1 - 2008/02/24/ PY - 2008 DA - 2008 Feb 24 KW - USA KW - Risk assessment KW - EPA KW - Data processing KW - Databases KW - Environmental assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40828473?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=6th+Annual+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=The+U.S.+EPAs+Support+for+Environmental+Rapid+Risk+Assessment+%28SERRA%29+Database+and+its+Application+to+Biothreat+DoseResponse+Data&rft.au=Taft%2C+S%3BNichols%2C+T%3BBaumel%2C+I%3BHines%2C+S%3BTaylor%2C+M%3BSonichMullin%2C+C%3BMcKean%2C+D&rft.aulast=Taft&rft.aufirst=S&rft.date=2008-02-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=6th+Annual+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/documents/2008Program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Is mean squared error a consistent indicator of accuracy for spatially structured demographic models? AN - 20597419; 8096725 AB - Animal demographic models are used in many disciplines and it is well-understood that their results and interpretation depend greatly on their structure and complexity. However, when models are constructed using data compiled from multiple sources it is difficult to objectively assess optimal structure and complexity. We explore the use of mean squared error (MSE) to identify optimal model structure. To illustrate, we compare the performance of a single-patch model versus a two-patch model for a migratory songbird in a spatially structured environment. In the single-patch model, mean fecundity across patches is estimated, and movement between patches is ignored. In the two-patch model, patch-specific reproductive rates are estimated, which requires the estimation and use of rates of movement between patches. MSE performed well as an indicator of optimal model structure, consistently conforming to our intuition about which model should be preferred under different combinations of model parameters. We show that (1) when dispersal offsets patch-specific demography, the single-patch model will always be favored, (2) with good estimates of vital rates, only modest sample sizes for dispersal are required to make the two-patch model more accurate, and (3) the same factors that result in large bias in the simple model also result in large sampling error for the two-patch model. Finally, our analyses also suggest that erroneous conclusions about optimal model complexity can be reached when additional structure is added to an already poorly parameterized model and we recommend a stepwise approach to the study of model complexity. JF - Ecological Modelling AU - Etterson, MA AU - Nagy, L R AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, MN 55804, United States, etterson.matthew@epa.gov Y1 - 2008/02/24/ PY - 2008 DA - 2008 Feb 24 SP - 202 EP - 208 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 211 IS - 1-2 SN - 0304-3800, 0304-3800 KW - Sustainability Science Abstracts; Ecology Abstracts KW - Mathematical models KW - Recruitment KW - Models KW - Demography KW - Fecundity KW - Sampling KW - Dispersal KW - M3 1010:Issues in Sustainable Development KW - D 04030:Models, Methods, Remote Sensing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20597419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecological+Modelling&rft.atitle=Is+mean+squared+error+a+consistent+indicator+of+accuracy+for+spatially+structured+demographic+models%3F&rft.au=Etterson%2C+MA%3BNagy%2C+L+R&rft.aulast=Etterson&rft.aufirst=MA&rft.date=2008-02-24&rft.volume=211&rft.issue=1-2&rft.spage=202&rft.isbn=&rft.btitle=&rft.title=Ecological+Modelling&rft.issn=03043800&rft_id=info:doi/10.1016%2Fj.ecolmodel.2007.09.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Models; Demography; Dispersal; Recruitment; Mathematical models; Sampling; Fecundity DO - http://dx.doi.org/10.1016/j.ecolmodel.2007.09.002 ER - TY - JOUR T1 - Analysis of perfluorinated carboxylic acids in soils II: optimization of chromatography and extraction. AN - 70262411; 18201708 AB - With the objective of detecting and quantitating low concentrations of perfluorinated carboxylic acids (PFCAs), including perfluorooctanoic acid (PFOA), in soils, we compared the analytical suitability of liquid chromatography columns containing three different stationary phases, two different liquid chromatography-tandem mass spectrometry (LC/MS/MS) systems, and eight combinations of sample-extract pretreatments, extractions and cleanups on three test soils. For the columns and systems we tested, we achieved the greatest analytical sensitivity for PFCAs using a column with a C(18) stationary phase in a Waters LC/MS/MS. In this system we achieved an instrument detection limit for PFOA of 270 ag/microL, equating to about 14 fg of PFOA on-column. While an elementary acetonitrile/water extraction of soils recovers PFCAs effectively, natural soil organic matter also dissolved in the extracts commonly imparts significant noise that appears as broad, multi-nodal, asymmetric peaks that coelute with several PFCAs. The intensity and elution profile of this noise is highly variable among soils and it challenges detection of low concentrations of PFCAs by decreasing the signal-to-noise contrast. In an effort to decrease this background noise, we investigated several methods of pretreatment, extraction and cleanup, in a variety of combinations, that used alkaline and unbuffered water, acetonitrile, tetrabutylammonium hydrogen sulfate, methyl-tert-butyl ether, dispersed activated carbon and solid-phase extraction. For the combined objectives of complete recovery and minimization of background noise, we have chosen: (1) alkaline pretreatment; (2) extraction with acetonitrile/water; (3) evaporation to dryness; (4) reconstitution with tetrabutylammonium-hydrogen-sulfate ion-pairing solution; (5) ion-pair extraction to methyl-tert-butyl ether; (6) evaporation to dryness; (7) reconstitution with 60/40 acetonitrile/water (v/v); and (8) analysis by LC/MS/MS. Using this method, we detected in all three of our test soils, endogenous concentrations of all of our PFCA analytes, C(6) through C(10)-the lowest concentrations being roughly 30 pg/g of dry soil for perfluorinated hexanoic and decanoic acids in an agricultural soil. JF - Journal of chromatography. A AU - Washington, John W AU - Henderson, W Matthew AU - Ellington, J Jackson AU - Jenkins, Thomas M AU - Evans, John J AD - United States Environmental Protection Agency, National Exposure Research Laboratory, 960 College Station Road, Athens, GA 30605, USA. Washington.John@epa.gov Y1 - 2008/02/15/ PY - 2008 DA - 2008 Feb 15 SP - 21 EP - 32 VL - 1181 IS - 1-2 SN - 0021-9673, 0021-9673 KW - Caprylates KW - 0 KW - Fluorocarbons KW - Soil Pollutants KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Tandem Mass Spectrometry KW - Chemical Fractionation -- methods KW - Chromatography, Liquid -- methods KW - Fluorocarbons -- analysis KW - Caprylates -- analysis KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70262411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chromatography.+A&rft.atitle=Analysis+of+perfluorinated+carboxylic+acids+in+soils+II%3A+optimization+of+chromatography+and+extraction.&rft.au=Washington%2C+John+W%3BHenderson%2C+W+Matthew%3BEllington%2C+J+Jackson%3BJenkins%2C+Thomas+M%3BEvans%2C+John+J&rft.aulast=Washington&rft.aufirst=John&rft.date=2008-02-15&rft.volume=1181&rft.issue=1-2&rft.spage=21&rft.isbn=&rft.btitle=&rft.title=Journal+of+chromatography.+A&rft.issn=00219673&rft_id=info:doi/10.1016%2Fj.chroma.2007.12.042 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-25 N1 - Date created - 2008-02-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.chroma.2007.12.042 ER - TY - JOUR T1 - Multi-laboratory testing of a screening method for world trade center (WTC) collapse dust. AN - 70153909; 18022215 AB - The September 11, 2001 attack on the World Trade Center (WTC) covered a large area of downtown New York City with dust and debris. This paper describes the testing of an analytical method designed to evaluate whether sampled dust contains dust that may have originated from the collapse of the WTC. Using dust samples collected from locations affected and not affected (referred to as 'background' locations) by the collapse, a scanning electron microscopy (SEM) analysis method was developed to screen for three materials that are believed to be present in large quantities in WTC dusts: slag wool, concrete, and gypsum. An inter-laboratory evaluation of the method was implemented by having eight laboratories analyze a number of 'blind' dust samples, consisting of confirmed background dust and confirmed background dust spiked with varying amounts of dust affected by the WTC collapse. The levels of gypsum and concrete in the spiked samples were indistinguishable from the levels in the background samples. Measurements of slag wool in dust demonstrated potential for distinguishing between spiked and background samples in spite of considerable within and between laboratory variability. Slag wool measurements appear to be sufficiently sensitive to distinguish dust spiked with 5% WTC-affected dust from 22 out of 25 background dust samples. Additional development work and inter-laboratory testing of the slag wool component will be necessary to improve the precision and accuracy of the method and reduce inter- and intra-laboratory variability from levels observed in the inter-laboratory evaluation. JF - The Science of the total environment AU - Rosati, Jacky A AU - Bern, Amy M AU - Willis, Robert D AU - Blanchard, Fredrick T AU - Conner, Teri L AU - Kahn, Henry D AU - Friedman, David AD - U.S. Environmental Protection Agency, Office of Research and Development (ORD), Research Triangle Park, NC 27711, USA. rosati.jacky@epa.gov Y1 - 2008/02/15/ PY - 2008 DA - 2008 Feb 15 SP - 514 EP - 519 VL - 390 IS - 2-3 SN - 0048-9697, 0048-9697 KW - Air Pollutants KW - 0 KW - Dental Cements KW - Dust KW - Calcium Sulfate KW - WAT0DDB505 KW - Index Medicus KW - Environmental Exposure -- adverse effects KW - Microscopy, Electron, Scanning KW - Dental Cements -- analysis KW - Dust -- analysis KW - Calcium Sulfate -- analysis KW - Air Pollutants -- analysis KW - September 11 Terrorist Attacks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70153909?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Multi-laboratory+testing+of+a+screening+method+for+world+trade+center+%28WTC%29+collapse+dust.&rft.au=Rosati%2C+Jacky+A%3BBern%2C+Amy+M%3BWillis%2C+Robert+D%3BBlanchard%2C+Fredrick+T%3BConner%2C+Teri+L%3BKahn%2C+Henry+D%3BFriedman%2C+David&rft.aulast=Rosati&rft.aufirst=Jacky&rft.date=2008-02-15&rft.volume=390&rft.issue=2-3&rft.spage=514&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=00489697&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-08 N1 - Date created - 2007-12-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Tissue dosimetry, metabolism and excretion of pentavalent and trivalent dimethylated arsenic in mice after oral administration AN - 19525056; 8092362 AB - Dimethylarsinic acid (DMA(V)) is a rat bladder carcinogen and the major urinary metabolite of administered inorganic arsenic in most mammals. This study examined the disposition of pentavalent and trivalent dimethylated arsenic in mice after acute oral administration. Adult female mice were administered [ super(1) super(4)C]-DMA(V) (0.6 or 60 mg As/kg) and sacrificed serially over 24 h. Tissues and excreta were collected for analysis of radioactivity. Other mice were administered unlabeled DMA(V) (0.6 or 60 mg As/kg) or dimethylarsinous acid (DMA(III)) (0.6 mg As/kg) and sacrificed at 2 or 24 h. Tissues (2 h) and urine (24 h) were collected and analyzed for arsenicals. Absorption, distribution and excretion of [ super(1) super(4)C]-DMA(V) were rapid, as radioactivity was detected in tissues and urine at 0.25 h. For low dose DMA(V) mice, there was a greater fractional absorption of DMA(V) and significantly greater tissue concentrations of radioactivity at several time points. Radioactivity distributed greatest to the liver (1-2% of dose) and declined to less than 0.05% in all tissues examined at 24 h. Urinary excretion of radioactivity was significantly greater in the 0.6 mg As/kg DMA(V) group. Conversely, fecal excretion of radioactivity was significantly greater in the high dose group. Urinary metabolites of DMA(V) included DMA(III), trimethylarsine oxide (TMAO), dimethylthioarsinic acid and trimethylarsine sulfide. Urinary metabolites of DMA(III) included TMAO, dimethylthioarsinic acid and trimethylarsine sulfide. DMA(V) was also excreted by DMA(III)-treated mice, showing its sensitivity to oxidation. TMAO was detected in tissues of the high dose DMA(V) group. The low acute toxicity of DMA(V) in the mouse appears to be due in part to its minimal retention and rapid elimination. JF - Toxicology and Applied Pharmacology AU - Hughes, M F AU - Devesa, V AU - Adair, B M AU - Conklin, S D AU - Creed, J T AU - Styblo, M AU - Kenyon, E M AU - Thomas, D J AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC 27711, USA, hughes.michaelf@epa.gov Y1 - 2008/02/15/ PY - 2008 DA - 2008 Feb 15 SP - 26 EP - 35 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 227 IS - 1 SN - 0041-008X, 0041-008X KW - Genetics Abstracts; Toxicology Abstracts KW - Arsenic KW - Urinary bladder KW - Dosimetry KW - Oral administration KW - Disposition KW - Metabolites KW - Carcinogens KW - Acute toxicity KW - Sulfide KW - Urine KW - Oxidation KW - Liver KW - oxides KW - Excretion KW - Radioactivity KW - dimethylarsinic acid KW - X 24390:Radioactive Materials KW - G 07870:Mammals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19525056?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Tissue+dosimetry%2C+metabolism+and+excretion+of+pentavalent+and+trivalent+dimethylated+arsenic+in+mice+after+oral+administration&rft.au=Hughes%2C+M+F%3BDevesa%2C+V%3BAdair%2C+B+M%3BConklin%2C+S+D%3BCreed%2C+J+T%3BStyblo%2C+M%3BKenyon%2C+E+M%3BThomas%2C+D+J&rft.aulast=Hughes&rft.aufirst=M&rft.date=2008-02-15&rft.volume=227&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.10.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Arsenic; Urinary bladder; Dosimetry; Oral administration; Metabolites; Disposition; Acute toxicity; Carcinogens; Sulfide; Urine; Oxidation; Liver; oxides; Excretion; Radioactivity; dimethylarsinic acid DO - http://dx.doi.org/10.1016/j.taap.2007.10.011 ER - TY - CPAPER T1 - EPA Water Sense and Outdoor Water Use Technologies. T2 - 2008 Sustainable Water Sources: Conservation and Resources Planning Conference and Exposition AN - 40772531; 4785149 JF - 2008 Sustainable Water Sources: Conservation and Resources Planning Conference and Exposition AU - Sieber, Roy Y1 - 2008/02/10/ PY - 2008 DA - 2008 Feb 10 KW - EPA KW - Water use KW - Technology KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40772531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Sustainable+Water+Sources%3A+Conservation+and+Resources+Planning+Conference+and+Exposition&rft.atitle=EPA+Water+Sense+and+Outdoor+Water+Use+Technologies.&rft.au=Sieber%2C+Roy&rft.aulast=Sieber&rft.aufirst=Roy&rft.date=2008-02-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Sustainable+Water+Sources%3A+Conservation+and+Resources+Planning+Conference+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - http://reports.awwa.org:8082/ReportServer?/Conference+Reports/Print+Pr ogram+Report&Conference=WS8&rs:Command=Render&rs:Format=PDF LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - New Directions in Product Labeling: WaterSense T2 - 2008 Sustainable Water Sources: Conservation and Resources Planning Conference and Exposition AN - 40767175; 4785051 JF - 2008 Sustainable Water Sources: Conservation and Resources Planning Conference and Exposition AU - Tanner, Stephanie L AU - Sieber, Roy Y1 - 2008/02/10/ PY - 2008 DA - 2008 Feb 10 KW - Water conservation KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767175?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Sustainable+Water+Sources%3A+Conservation+and+Resources+Planning+Conference+and+Exposition&rft.atitle=New+Directions+in+Product+Labeling%3A+WaterSense&rft.au=Tanner%2C+Stephanie+L%3BSieber%2C+Roy&rft.aulast=Tanner&rft.aufirst=Stephanie&rft.date=2008-02-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Sustainable+Water+Sources%3A+Conservation+and+Resources+Planning+Conference+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - http://reports.awwa.org:8082/ReportServer?/Conference+Reports/Print+Pr ogram+Report&Conference=WS8&rs:Command=Render&rs:Format=PDF LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of an Intensity Error Model for Affymetrix GeneChips using a Wholly-Defined, Control Dataset. T2 - 2008 Meeting of the Association of Biomolecular Resource Facilities (ABRF 2008) AN - 40790200; 4789272 JF - 2008 Meeting of the Association of Biomolecular Resource Facilities (ABRF 2008) AU - Ward, B AU - Vallanat, B Y1 - 2008/02/09/ PY - 2008 DA - 2008 Feb 09 KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40790200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2008+Meeting+of+the+Association+of+Biomolecular+Resource+Facilities+%28ABRF+2008%29&rft.atitle=Evaluation+of+an+Intensity+Error+Model+for+Affymetrix+GeneChips+using+a+Wholly-Defined%2C+Control+Dataset.&rft.au=Ward%2C+B%3BVallanat%2C+B&rft.aulast=Ward&rft.aufirst=B&rft.date=2008-02-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2008+Meeting+of+the+Association+of+Biomolecular+Resource+Facilities+%28ABRF+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/viewer/?mkey=%7B07D7989D-B414-4476-9074 -4FD60E6FFD4E%7D LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Contaminant concentrations in whole-body fish and shellfish from US estuaries AN - 759320580; 13770319 AB - Persistent bioaccumulative and toxic (PBT) pollutants are chemical contaminants that pose risks to ecosystems and human health. For these reasons, available tissue contaminant data from the US EPA Environmental Monitoring and Assessment Program's National Coastal Assessment were examined to estimate to what areal extent PBTs are found in US estuarine resources. The data document composite, whole-body tissue chemical concentrations for 736 sampling sites across Northeast, Southeast, Gulf of Mexico, and West Coast estuaries. Tissue chemical concentrations were compared to US EPA non-cancer risk guidelines for recreational fishers, because of a lack of ecological guidelines for these chemical concentrations. Samples were analyzed for 23 PAH compounds, 21 PCB congeners, 6 DDT derivatives and metabolites, 14 chlorinated pesticides (other than DDT) and 13 metals, including mercury. Total PCBs were found to exceed recreational fisher guidelines most frequently (31% of samples evaluated), followed by mercury (29%), total PAHs (21%), and DDT and its metabolites, DDD and DDE (11%). Toxaphene, cadmium and dieldrin were found but in fewer than 1% of the samples. JF - Environmental Monitoring and Assessment AU - Harvey, James AU - Harwell, Linda AU - Summers, JKevin AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Gulf Ecology Division, US Environmental Protection Agency, 1 Sabine Island Drive, Gulf Breeze, FL, 32561-5299, USA, harvey.jim@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 403 EP - 412 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 137 IS - 1-3 SN - 0167-6369, 0167-6369 KW - ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts; Aqualine Abstracts; Water Resources Abstracts; Pollution Abstracts KW - Metabolites KW - Lead KW - ASW, Mexico Gulf KW - Risk KW - USA KW - Pollutants KW - Assessments KW - DDT KW - Mercury KW - Standards KW - Monitoring KW - SW 3030:Effects of pollution KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759320580?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Monitoring+and+Assessment&rft.atitle=Contaminant+concentrations+in+whole-body+fish+and+shellfish+from+US+estuaries&rft.au=Harvey%2C+James%3BHarwell%2C+Linda%3BSummers%2C+JKevin&rft.aulast=Harvey&rft.aufirst=James&rft.date=2008-02-01&rft.volume=137&rft.issue=1-3&rft.spage=403&rft.isbn=&rft.btitle=&rft.title=Environmental+Monitoring+and+Assessment&rft.issn=01676369&rft_id=info:doi/10.1007%2Fs10661-007-9776-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Risk; Assessments; Pollutants; DDT; Mercury; Metabolites; Standards; Monitoring; Lead; ASW, Mexico Gulf; USA DO - http://dx.doi.org/10.1007/s10661-007-9776-1 ER - TY - JOUR T1 - Dose-related effects following oral exposure of 2,4-dinitrotoluene on the Western fence lizard, Sceloporus occidentalis. AN - 70412690; 18348623 AB - 2,4-dintitrotoluene (2,4-DNT) is an explosive frequently found in the soil of military installations. Because reptiles can be common on these sites, ecological risk assessments for compounds such as 2,4-DNT could be improved with toxicity data specific to reptiles. Western fence lizards, Sceloporus occidentalis, were used to develop a laboratory toxicity model for reptiles. A hierarchical approach was used; acute to subchronic studies were conducted to provide toxicity data relevant to short- and long-term exposures. First, a modified median lethal dose (LD50) study was conducted on male and female lizards using a stage-wise probit model. The LD50 was 577 mg/kg for female and 380 mg/kg for male lizards. Subsequently, a subacute experiment was conducted to further assess 2,4-DNT toxicity to male lizards and to define exposure levels for a longer term, subchronic study. The subchronic study was conducted for 60 consecutive days; male lizards were exposed to 0, 9, 15, 25, 42, 70 mg/kg/d. Dose-dependent mortality was observed in the three highest dose groups (25, 42, and 70 mg/kg/d); all other animals survived the study duration. Benchmark dose model calculations based on mortality indicated a 5% effect level of 15.8 mg/kg/d. At study termination, a gross necropsy was performed, organ weights were taken, and blood was collected for clinical and hematological analysis. Body weight, kidney weight, food consumption, postdose observations, and blood chemistries all were found to be significantly different from controls at doses above 9 mg/kg/d. Also, preliminary results suggest behavioral observations, and reduced food consumption may be a sensitive indicator of toxicity. The present study indicates Sceloporus occidentalis is suitable for evaluating toxicity of compounds to reptilian species. JF - Environmental toxicology and chemistry AU - Suski, Jamie G AU - Salice, Christopher AU - Houpt, John T AU - Bazar, Matthew A AU - Talent, Larry G AD - US Army Center for Health Promotion and Preventive Medicine, Aberdeen Proving Ground, MD 21010, USA. suski.jamie@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 352 EP - 359 VL - 27 IS - 2 SN - 0730-7268, 0730-7268 KW - Dinitrobenzenes KW - 0 KW - Environmental Pollutants KW - 2,4-dinitrotoluene KW - 6741D310ED KW - Index Medicus KW - Administration, Oral KW - Animals KW - Drug Administration Schedule KW - Dose-Response Relationship, Drug KW - Lethal Dose 50 KW - Male KW - Environmental Pollutants -- pharmacology KW - Dinitrobenzenes -- administration & dosage KW - Lizards KW - Dinitrobenzenes -- pharmacology KW - Environmental Pollutants -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70412690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Dose-related+effects+following+oral+exposure+of+2%2C4-dinitrotoluene+on+the+Western+fence+lizard%2C+Sceloporus+occidentalis.&rft.au=Suski%2C+Jamie+G%3BSalice%2C+Christopher%3BHoupt%2C+John+T%3BBazar%2C+Matthew+A%3BTalent%2C+Larry+G&rft.aulast=Suski&rft.aufirst=Jamie&rft.date=2008-02-01&rft.volume=27&rft.issue=2&rft.spage=352&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F07-149R.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-01 N1 - Date created - 2008-03-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1897/07-149R.1 ER - TY - JOUR T1 - Cross-species comparison of conazole fungicide metabolites using rat and rainbow trout (Onchorhynchus mykiss) hepatic microsomes and purified human CYP 3A4. AN - 70377042; 18323127 AB - Ecological risk assessment frequently relies on cross-species extrapolation to predict acute toxicity from chemical exposures. A major concern for environmental risk characterization is the degree of uncertainty in assessing xenobiotic biotransformation processes. Although inherently complex, metabolite identification is critical to risk assessment since the product(s) formed may pose a greater toxicological threat than the parent molecule. This issue is further complicated by differences observed in metabolic transformation pathways among species. Conazoles represent an important class of azole fungicides that are widely used in both pharmaceutical and agricultural applications. The antifungal property of conazoles occurs via complexation with the cytochrome P450 monooxygenases (CYP) responsible for mediating fungal cell wall synthesis. This mode of action has cause for concern regarding the potential adverse impact of conazoles on the broad spectrum of CYP-based processes within mammalian and aquatic species. In this study, in vitro metabolic profiles were determined for thirteen conazole fungicides using rat and rainbow trout (Oncorhynchus mykiss) liver microsomes and purified human CYP 3A4. Results showed that 10 out of the 13 conazoles tested demonstrated identical metabolite profiles among rat and trout microsomes, and these transformations were well conserved via both aromatic and aliphatic hydroxylation and carbonyl reduction processes. Furthermore, nearly all metabolites detected in the rat and trout microsomal assays were detected within the human CYP 3A4 assays. These results indicate a high degree of metabolic conservation among species with an equivalent isozyme activity of human CYP 3A4 being present in both the rat and trout, and provides insight into xenobiotic biotransformations needed for accurate risk assessment. JF - Environmental science & technology AU - Mazur, Christopher S AU - Kenneke, John F AD - U.S. EPA, National Exposure Research Laboratory, Ecosystems Research Division, 960 College Station Rd., Athens, GA 30605, USA. mazur.chris@epa.gov Y1 - 2008/02/01/ PY - 2008 DA - 2008 Feb 01 SP - 947 EP - 954 VL - 42 IS - 3 SN - 0013-936X, 0013-936X KW - Fungicides, Industrial KW - 0 KW - Triazoles KW - propiconazole KW - 142KW8TBSR KW - triadimefon KW - 1HW039CJF0 KW - CYP3A4 protein, human KW - EC 1.14.13.67 KW - Cytochrome P-450 CYP3A KW - EC 1.14.14.1 KW - Index Medicus KW - Rats KW - Mass Spectrometry KW - Animals KW - Rats, Sprague-Dawley KW - Humans KW - Reference Standards KW - Chromatography, Liquid KW - Triazoles -- chemistry KW - Triazoles -- metabolism KW - Species Specificity KW - Male KW - Cytochrome P-450 CYP3A -- isolation & purification KW - Fungicides, Industrial -- chemistry KW - Microsomes, Liver -- metabolism KW - Fungicides, Industrial -- metabolism KW - Oncorhynchus mykiss -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70377042?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Cross-species+comparison+of+conazole+fungicide+metabolites+using+rat+and+rainbow+trout+%28Onchorhynchus+mykiss%29+hepatic+microsomes+and+purified+human+CYP+3A4.&rft.au=Mazur%2C+Christopher+S%3BKenneke%2C+John+F&rft.aulast=Mazur&rft.aufirst=Christopher&rft.date=2008-02-01&rft.volume=42&rft.issue=3&rft.spage=947&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-12 N1 - Date created - 2008-03-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Comparing surface residue transfer efficiencies to hands using polar and nonpolar fluorescent tracers. AN - 70375666; 18323125 AB - Transfer of chemicals from contaminated surfaces such as foliage, floors, and furniture is a potentially significant source of both occupational exposure and children's residential exposure. Increased understanding of relevant factors influencing transfers from contaminated surfaces to skin and resulting dermal-loading will reduce uncertainty in exposure assessment. In a previously reported study, a fluorescence imaging system was developed, tested, and used to measure transfer of riboflavin residues from surfaces to hands. Parameters evaluated included surface type, surface loading, contact motion, pressure, duration, and skin condition. Results of the initial study indicated that contact duration and pressure were not significant for the range of values tested, but that there are potentially significant differences in transfer efficiencies of different compounds. In the study reported here, experimental methods were refined and additional transfer data were collected. A second fluorescent tracer, Uvitex OB, with very different physicochemical properties than riboflavin, was also evaluated to better characterize the range of transfers that may be expected for a variety of compounds. Fluorescent tracers were applied individually to surfaces and transfers to skin were measured after repeated hand contacts with the surface. Additional trials were conducted to compare transfer of tracers and co-applied pesticide residues. Results of this study indicate that dermal loadings of both tracers increase through the seventh brief contact. Dermal loading of Uvitex tends to increase at a higher rate than dermal loadings of riboflavin. Measurement of co-applied tracer and pesticide suggest results for these two tracers may provide reasonable bounding estimates of pesticide transfer. JF - Environmental science & technology AU - Hubal, Elaine A Cohen AU - Nishioka, Marcia G AU - Ivancic, William A AU - Morara, Michele AU - Egeghy, Peter P AD - National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina 27711, USA. hubal.elaine@epa.gov Y1 - 2008/02/01/ PY - 2008 DA - 2008 Feb 01 SP - 934 EP - 939 VL - 42 IS - 3 SN - 0013-936X, 0013-936X KW - Fluorescent Dyes KW - 0 KW - Pesticides KW - Riboflavin KW - TLM2976OFR KW - Index Medicus KW - Analysis of Variance KW - Skin KW - Humans KW - Riboflavin -- metabolism KW - Fluorescent Dyes -- metabolism KW - Environmental Exposure KW - Hand UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70375666?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Comparing+surface+residue+transfer+efficiencies+to+hands+using+polar+and+nonpolar+fluorescent+tracers.&rft.au=Hubal%2C+Elaine+A+Cohen%3BNishioka%2C+Marcia+G%3BIvancic%2C+William+A%3BMorara%2C+Michele%3BEgeghy%2C+Peter+P&rft.aulast=Hubal&rft.aufirst=Elaine+A&rft.date=2008-02-01&rft.volume=42&rft.issue=3&rft.spage=934&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-12 N1 - Date created - 2008-03-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Linking solid phase speciation of Pb sequestered to birnessite to oral Pb bioaccessibility: implications for soil remediation. AN - 70371977; 18323102 AB - Lead (Pb) sorption onto oxide surfaces in soils may strongly influence the risk posed from incidental ingestion of lead-contaminated soils. In this study, Pb was sorbed to a model soil mineral, birnessite, and was placed in a simulated gastrointestinal tract (in vitro) to simulate the possible effects of ingestion of a soil contaminated with Pb. The changes in Pb speciation were determined using extended X-ray absorption fine structure and X-ray absorption near edge spectroscopy. Birnessite has a very high affinity for Pb with a sorption maximum of 0.59 mol Pb kg(-1) (approximately 12% Pb sorbed by mass) in which there was no detectable bioaccessible Pb (< 0.002%). Surface speciation of the birnessite Pb was determined to be a triple corner sharing complex in the birnessite interlayer. Lead sorbed to Mn oxide in contaminated media will have a very low (approximately equal to 0) Pb bioaccessibility and present little risk associated with incidental ingestion of soil. These results suggest that birnessite, and other Mn oxides would be powerful remediation tools for Pb-contaminated media because of their high affinity for Pb. JF - Environmental science & technology AU - Beak, Douglas G AU - Basta, Nicholas T AU - Scheckel, Kirk G AU - Traina, Samuel J AD - School of Environment and Natural Resources, Ohio State University, 2021 Coffey Rd, Columbus, Ohio 43210, USA. beak.douglas@epa.gov Y1 - 2008/02/01/ PY - 2008 DA - 2008 Feb 01 SP - 779 EP - 785 VL - 42 IS - 3 SN - 0013-936X, 0013-936X KW - Oxides KW - 0 KW - Soil KW - birnessite KW - Lead KW - 2P299V784P KW - Manganese KW - 42Z2K6ZL8P KW - Index Medicus KW - Manganese -- metabolism KW - X-Ray Diffraction KW - Fourier Analysis KW - Biological Availability KW - Lead -- isolation & purification KW - Environmental Restoration and Remediation KW - Lead -- metabolism KW - Oxides -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70371977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Linking+solid+phase+speciation+of+Pb+sequestered+to+birnessite+to+oral+Pb+bioaccessibility%3A+implications+for+soil+remediation.&rft.au=Beak%2C+Douglas+G%3BBasta%2C+Nicholas+T%3BScheckel%2C+Kirk+G%3BTraina%2C+Samuel+J&rft.aulast=Beak&rft.aufirst=Douglas&rft.date=2008-02-01&rft.volume=42&rft.issue=3&rft.spage=779&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-12 N1 - Date created - 2008-03-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Continuous and semicontinuous monitoring techniques for particulate matter mass and chemical components: a synthesis of findings from EPA's Particulate Matter Supersites Program and related studies. AN - 70361180; 18318336 AB - The U.S. Environmental Protection Agency (EPA) established the Particulate Matter (PM) Supersites Program to provide key stakeholders (government and private sector) with significantly improved information needed to develop effective and efficient strategies for reducing PM on urban and regional scales. All Supersites projects developed and evaluated methods and instruments, and significant advances have been made and applied within these programs to yield new insights to our understanding of PM accumulation in air as well as improved source-receptor relationships. The tested methods include a variety of continuous and semicontinuous instruments typically with a time resolution of an hour or less. These methods often overcome many of the limitations associated with measuring atmospheric PM mass concentrations by daily filter-based methods (e.g., potential positive or negative sampling artifacts). Semicontinuous coarse and ultrafine mass measurement methods also were developed and evaluated. Other semicontinuous monitors tested measured the major components of PM such as nitrate, sulfate, ammonium, organic and elemental carbon, trace elements, and water content of the aerosol as well as methods for other physical properties of PM, such as number concentration, size distribution, and particle density. Particle mass spectrometers, although unlikely to be used in national routine monitoring networks in the foreseeable future because of their complex technical requirements and cost, are mentioned here because of the wealth of new information they provide on the size-resolved chemical composition of atmospheric particles on a near continuous basis. Particle mass spectrometers likely represent the greatest advancement in PM measurement technology during the last decade. The improvements in time resolution achieved by the reported semicontinuous methods have proven to be especially useful in characterizing ambient PM, and are becoming essential in allowing scientists to investigate sources of particulate pollution and to probe into the dynamics and mechanisms of aerosol formation in the atmosphere. JF - Journal of the Air & Waste Management Association (1995) AU - Solomon, Paul A AU - Sioutas, Constantinos AD - U.S. Environmental Protection Agency, Office of Research and Development, Las Vegas, NV, USA. solomon.paul@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 164 EP - 195 VL - 58 IS - 2 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Particulate Matter KW - Water KW - 059QF0KO0R KW - Carbon KW - 7440-44-0 KW - Index Medicus KW - Water -- analysis KW - United States KW - Mass Spectrometry KW - United States Environmental Protection Agency KW - Particle Size KW - Environmental Restoration and Remediation KW - Carbon -- analysis KW - Air Pollutants -- analysis KW - Particulate Matter -- analysis KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70361180?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Continuous+and+semicontinuous+monitoring+techniques+for+particulate+matter+mass+and+chemical+components%3A+a+synthesis+of+findings+from+EPA%27s+Particulate+Matter+Supersites+Program+and+related+studies.&rft.au=Solomon%2C+Paul+A%3BSioutas%2C+Constantinos&rft.aulast=Solomon&rft.aufirst=Paul&rft.date=2008-02-01&rft.volume=58&rft.issue=2&rft.spage=164&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-09 N1 - Date created - 2008-03-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Science linking environmental contaminant exposures with fertility and reproductive health impacts in the adult female. AN - 70348356; 18308071 AB - To broadly review the recent literature linking environmental factors and adult female reproductive health for the UCSF-CHE Summit on Environmental Challenges to Reproductive Health and Fertility. Reviewed articles indexed in PubMed from 1999-2007 addressing environment and puberty, menstrual and ovarian function, fertility, and menopause. The strongest evidence of environmental contaminant exposures interfering with healthy reproductive function in adult females is for heavy metals, particularly lead. Compounds that can influence hormone function, including pesticides and persistent pollutants, are also associated with risk. The pattern of effects for these endocrine-active compounds is often complex, with no clear dose response, but alterations in function and poor reproductive health outcomes are observed. From a clinical perspective, most modifiable risk appears to be associated with exposures in unique populations (contaminated fish consumers) or occupational groups (farmworkers). Many compounds have demonstrated increased risks for reproductive health impairment in women, but the literature is largely cross-sectional in nature and too sparse or inconclusive to support causal inference. Reproductive function in adult females is impaired by lead exposure. Pesticides and persistent pollutants can alter hormone function resulting in adverse reproductive health effects. Coordinated research is needed to address contaminant effects across the life span. JF - Fertility and sterility AU - Mendola, Pauline AU - Messer, Lynne C AU - Rappazzo, Kristen AD - US EPA, Human Studies Division, National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina 27711, USA. pim9@cdc.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - e81 EP - e94 VL - 89 IS - 2 Suppl KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - Humans KW - Adult KW - Environmental Exposure KW - Female KW - Reproductive Medicine -- trends KW - Environmental Pollutants -- toxicity KW - Environmental Health -- trends KW - Infertility, Female -- chemically induced KW - Fertility -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70348356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fertility+and+sterility&rft.atitle=Science+linking+environmental+contaminant+exposures+with+fertility+and+reproductive+health+impacts+in+the+adult+female.&rft.au=Mendola%2C+Pauline%3BMesser%2C+Lynne+C%3BRappazzo%2C+Kristen&rft.aulast=Mendola&rft.aufirst=Pauline&rft.date=2008-02-01&rft.volume=89&rft.issue=2+Suppl&rft.spage=e81&rft.isbn=&rft.btitle=&rft.title=Fertility+and+sterility&rft.issn=1556-5653&rft_id=info:doi/10.1016%2Fj.fertnstert.2007.12.036 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-09 N1 - Date created - 2008-02-29 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment On: Fertil Steril. 2008 Feb;89(2 Suppl):e95 [18308072] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.fertnstert.2007.12.036 ER - TY - JOUR T1 - The effect of environmental chemicals on human health. AN - 70345463; 18308056 JF - Fertility and sterility AU - Birnbaum, Linda S AD - Experimental Toxicology Division, US EPA/NHEERL, Research Triangle Park, North Carolina 27709, USA. Birnbaum.Linda@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 1 VL - 89 IS - 2 Suppl KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - Animals KW - Humans KW - Environmental Pollutants -- toxicity KW - Environmental Health -- trends KW - Health Status UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70345463?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fertility+and+sterility&rft.atitle=The+effect+of+environmental+chemicals+on+human+health.&rft.au=Birnbaum%2C+Linda+S&rft.aulast=Birnbaum&rft.aufirst=Linda&rft.date=2008-02-01&rft.volume=89&rft.issue=2+Suppl&rft.spage=e31&rft.isbn=&rft.btitle=&rft.title=Fertility+and+sterility&rft.issn=1556-5653&rft_id=info:doi/10.1016%2Fj.fertnstert.2007.12.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-09 N1 - Date created - 2008-02-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.fertnstert.2007.12.022 ER - TY - JOUR T1 - A summary of total mercury concentrations in flora and fauna near common contaminant sources in the Gulf of Mexico. AN - 70344606; 17980902 AB - Total mercury concentrations are summarized for environmental media and biota collected from near-coastal areas, several impacted by contaminant sources common to the Gulf of Mexico. Water, sediment, fish, blue crabs, oysters, clams, mussels, periphyton and seagrasses were collected during 1993-2002 from targeted areas affected by point and non-point source contaminants. Mean concentrations in water and sediment were 0.02 (+/-1 standard deviation=0.06) microg l(-1) and 96.3 (230.8) ng g(-1) dry wt, respectively. Mean total mercury concentrations in fish, blue crabs, brackish clams and mussels were significantly greater than those in sediment, seagrass, colonized periphyton and oysters. Concentrations (ng g(-1) dry wt) averaged 23.1 (two seagrass species), 220.1 (oysters), 287.8 (colonized periphyton), 604.0 (four species of freshwater mussels), 772.4 (brackish clam), 857.9 (blue crabs) and 933.1 (nine fish species). Spatial, intraspecific and interspecific variability in results limited most generalizations concerning the relative mercury contributions of different stressor types. However, concentrations were significantly greater for some biota collected from areas receiving wastewater discharges and golf course runoff (fish), agricultural runoff (oysters) and urban stormwater runoff (colonized periphyton and sediment). Marine water quality criteria and proposed sediment quality guidelines were exceeded in 1-12% of total samples. At least one seafood consumption guideline, criteria or screening value were exceeded in edible tissues of blue crabs (6% total samples) and nine fish species (8-33% total samples) but all residues were less than the US Federal Drug Administration action limit of 1.0 ppm and the few reported toxic effect concentrations available for the targeted biota. JF - Chemosphere AU - Lewis, M AU - Chancy, C AD - United States Environmental Protection Agency, National Health and Environmental Effects, Research Laboratory, Gulf Ecology Division, Gulf Breeze, FL 32561, USA. lewis.michael@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 2016 EP - 2024 VL - 70 IS - 11 SN - 0045-6535, 0045-6535 KW - Environmental Pollutants KW - 0 KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - Environmental Monitoring KW - Oceans and Seas KW - Animals KW - Geologic Sediments -- analysis KW - Florida KW - Alabama KW - Hydrocharitaceae KW - Alismatidae -- metabolism KW - Environmental Pollutants -- metabolism KW - Mercury -- metabolism KW - Invertebrates -- metabolism KW - Mercury -- analysis KW - Food Contamination -- analysis KW - Seafood -- analysis KW - Fishes -- metabolism KW - Environmental Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70344606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=A+summary+of+total+mercury+concentrations+in+flora+and+fauna+near+common+contaminant+sources+in+the+Gulf+of+Mexico.&rft.au=Lewis%2C+M%3BChancy%2C+C&rft.aulast=Lewis&rft.aufirst=M&rft.date=2008-02-01&rft.volume=70&rft.issue=11&rft.spage=2016&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-20 N1 - Date created - 2008-03-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Potentiation of pulmonary reflex response to capsaicin 24h following whole-body acrolein exposure is mediated by TRPV1. AN - 70260222; 17950047 AB - Pulmonary C-fibers are stimulated by irritant air pollutants producing apnea, bronchospasm, and decrease in HR. Chemoreflex responses resulting from C-fiber activation are sometimes mediated by TRPV1 and release of substance P. While acrolein has been shown to stimulate C-fibers, the persistence of acrolein effects and the role of C-fibers in these responses are unknown. These experiments were designed to determine the effects of whole-body acrolein exposure and pulmonary chemoreflex response post-acrolein. Rats were exposed to either air or 3 ppm acrolein for 3 h while ventilatory function and HR were measured; 1-day later response to capsaicin challenge was measured in anesthetized rats. Rats experienced apnea and decrease in HR upon exposure to acrolein, which was not affected by either TRPV1 antagonist or NK(1)R antagonist pretreatment. Twenty-four hours later, capsaicin caused apnea and bronchoconstriction in control rats, which was potentiated in rats exposed to acrolein. Pretreatment with TRPV1 antagonist or NK(1)R antagonist prevented potentiation of apneic response and bronchoconstriction 24h post-exposure. These data suggest that although potentiation of pulmonary chemoreflex response 24h post-acrolein is mediated by TRPV1 and release of substance P, cardiopulmonary inhibition during whole-body acrolein exposure is mediated through other mechanisms. JF - Respiratory physiology & neurobiology AU - Hazari, Mehdi S AU - Rowan, William H AU - Winsett, Darrell W AU - Ledbetter, Allen D AU - Haykal-Coates, Najwa AU - Watkinson, William P AU - Costa, Daniel L AD - Curriculum in Toxicology, University of North Carolina, Chapel Hill, NC 27599-7270, United States. hazari.mehdi@epa.gov Y1 - 2008/02/01/ PY - 2008 DA - 2008 Feb 01 SP - 160 EP - 171 VL - 160 IS - 2 SN - 1569-9048, 1569-9048 KW - Air Pollutants KW - 0 KW - Irritants KW - Receptors, Neurokinin-1 KW - Sensory System Agents KW - TRPV Cation Channels KW - TRPV1 receptor KW - Substance P KW - 33507-63-0 KW - Acrolein KW - 7864XYD3JJ KW - Capsaicin KW - S07O44R1ZM KW - Index Medicus KW - Animals KW - Sensory System Agents -- administration & dosage KW - Pulmonary Ventilation -- physiology KW - Respiratory System -- metabolism KW - Respiratory Mechanics -- drug effects KW - Substance P -- metabolism KW - Respiration -- drug effects KW - Receptors, Neurokinin-1 -- metabolism KW - Nerve Fibers, Unmyelinated -- drug effects KW - Pulmonary Ventilation -- drug effects KW - Rats KW - Air Pollutants -- pharmacology KW - Reflex -- physiology KW - Rats, Sprague-Dawley KW - Receptors, Neurokinin-1 -- drug effects KW - Reflex -- drug effects KW - Nerve Fibers, Unmyelinated -- metabolism KW - Respiratory System -- cytology KW - Respiratory Mechanics -- physiology KW - Drug Synergism KW - Sensory System Agents -- pharmacology KW - Male KW - Respiratory System -- drug effects KW - Acrolein -- pharmacology KW - TRPV Cation Channels -- metabolism KW - Chemoreceptor Cells -- physiology KW - Capsaicin -- administration & dosage KW - Chemoreceptor Cells -- drug effects KW - Irritants -- pharmacology KW - Capsaicin -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70260222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Respiratory+physiology+%26+neurobiology&rft.atitle=Potentiation+of+pulmonary+reflex+response+to+capsaicin+24h+following+whole-body+acrolein+exposure+is+mediated+by+TRPV1.&rft.au=Hazari%2C+Mehdi+S%3BRowan%2C+William+H%3BWinsett%2C+Darrell+W%3BLedbetter%2C+Allen+D%3BHaykal-Coates%2C+Najwa%3BWatkinson%2C+William+P%3BCosta%2C+Daniel+L&rft.aulast=Hazari&rft.aufirst=Mehdi&rft.date=2008-02-01&rft.volume=160&rft.issue=2&rft.spage=160&rft.isbn=&rft.btitle=&rft.title=Respiratory+physiology+%26+neurobiology&rft.issn=15699048&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-06 N1 - Date created - 2008-02-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Quantitative PCR for detection and enumeration of genetic markers of bovine fecal pollution. AN - 70254349; 18065617 AB - Accurate assessment of health risks associated with bovine (cattle) fecal pollution requires a reliable host-specific genetic marker and a rapid quantification method. We report the development of quantitative PCR assays for the detection of two recently described bovine feces-specific genetic markers and a method for the enumeration of these markers using a Markov chain Monte Carlo approach. Both assays exhibited a range of quantification from 25 to 2 x 10(6) copies of target DNA, with a coefficient of variation of <2.1%. One of these assays can be multiplexed with an internal amplification control to simultaneously detect the bovine-specific genetic target and presence of amplification inhibitors. The assays detected only cattle fecal specimens when tested against 204 fecal DNA extracts from 16 different animal species and also demonstrated a broad distribution among individual bovine samples (98 to 100%) collected from five geographically distinct locations. The abundance of each bovine-specific genetic marker was measured in 48 individual samples and compared to quantitative PCR-enumerated quantities of rRNA gene sequences representing total Bacteroidetes, Bacteroides thetaiotaomicron, and enterococci in the same specimens. Acceptable assay performance combined with the prevalence of DNA targets across different cattle populations provides experimental evidence that these quantitative assays will be useful in monitoring bovine fecal pollution in ambient waters. JF - Applied and environmental microbiology AU - Shanks, Orin C AU - Atikovic, Emina AU - Blackwood, A Denene AU - Lu, Jingrang AU - Noble, Rachel T AU - Domingo, Jorge Santo AU - Seifring, Shawn AU - Sivaganesan, Mano AU - Haugland, Richard A AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, 26 West Martin Luther King Drive, Cincinnati, OH 45268, USA. shanks.orin@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 745 EP - 752 VL - 74 IS - 3 KW - DNA Primers KW - 0 KW - DNA, Bacterial KW - DNA, Ribosomal KW - Genetic Markers KW - Index Medicus KW - Animals KW - Cattle KW - Plasmids -- genetics KW - DNA, Bacterial -- isolation & purification KW - Markov Chains KW - Monte Carlo Method KW - DNA, Ribosomal -- analysis KW - DNA, Bacterial -- analysis KW - Species Specificity KW - Genes, rRNA KW - Water Pollution -- analysis KW - Feces -- microbiology KW - Genetic Markers -- genetics KW - Polymerase Chain Reaction -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70254349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Quantitative+PCR+for+detection+and+enumeration+of+genetic+markers+of+bovine+fecal+pollution.&rft.au=Shanks%2C+Orin+C%3BAtikovic%2C+Emina%3BBlackwood%2C+A+Denene%3BLu%2C+Jingrang%3BNoble%2C+Rachel+T%3BDomingo%2C+Jorge+Santo%3BSeifring%2C+Shawn%3BSivaganesan%2C+Mano%3BHaugland%2C+Richard+A&rft.aulast=Shanks&rft.aufirst=Orin&rft.date=2008-02-01&rft.volume=74&rft.issue=3&rft.spage=745&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=1098-5336&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-04 N1 - Date created - 2008-02-04 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Appl Environ Microbiol. 2005 Jun;71(6):3041-8 [15933000] Water Res. 2005 Feb;39(4):559-68 [15707628] Appl Environ Microbiol. 2005 Jun;71(6):3184-91 [15933020] Appl Environ Microbiol. 2006 Jun;72(6):4012-9 [16751510] Appl Environ Microbiol. 2006 Jun;72(6):4054-60 [16751515] Appl Environ Microbiol. 2006 Jun;72(6):4214-24 [16751534] J Microbiol Methods. 2006 Aug;66(2):321-30 [16469400] Appl Environ Microbiol. 2006 Aug;72(8):5537-46 [16885307] Appl Environ Microbiol. 2006 Aug;72(8):5610-4 [16885315] Environ Sci Technol. 2007 Mar 15;41(6):1856-62 [17410775] Appl Environ Microbiol. 2007 Apr;73(8):2416-22 [17209067] J Water Health. 2008 Jun;6(2):225-37 [18209285] J Appl Microbiol. 1998 Dec;85 Suppl 1:83S-89S [21182696] Appl Environ Microbiol. 2000 Apr;66(4):1587-94 [10742246] Appl Environ Microbiol. 2000 Oct;66(10):4571-4 [11010920] Nucleic Acids Res. 2001 Jan 1;29(1):181-4 [11125085] Syst Appl Microbiol. 2000 Dec;23(4):556-62 [11249026] Appl Environ Microbiol. 2002 Mar;68(3):1165-72 [11872464] Appl Environ Microbiol. 2003 Aug;69(8):4714-9 [12902262] Water Res. 2003 Sep;37(16):3978-82 [12909116] Nucleic Acids Res. 2003 Oct 15;31(20):e123 [14530456] Nucleic Acids Res. 1988 Aug 11;16(15):7351-67 [3045756] BMJ. 1991 Dec 7;303(6815):1444-5 [1773151] Nature. 1992 Oct 8;359(6395):557-8 [1383831] Nucleic Acids Res. 1994 Nov 11;22(22):4673-80 [7984417] J Infect Dis. 1999 Oct;180(4):1275-81 [10479158] Appl Environ Microbiol. 2005 Jun;71(6):3179-83 [15933019] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Sensory irritation response in rats: modeling, analysis and validation. AN - 70215415; 17914657 AB - Inhaled gases can cause respiratory depression by irritating (stimulating) nerves in the nasal cavity. Respiratory depression, in turn, decreases the rate of delivery of those gases to the stimulated nerves, potentially leading to a complex feedback response. In order to better understand how the nervous system responds to such chemicals, a mathematical model is created to describe how the presence of irritants affects respiration in the rat. The ordinary differential equation model describes the dosimetry of these reactive gases in the respiratory tract, with particular focus on the physiology of the upper respiratory tract, and on the neurological control of respiration rate due to signaling from the irritant-responsive nerves in the nasal cavity. The ventilation equation is altered to account for an apparent change in dynamics between the initial ventilation decrease and the recovery to steady state as seen in formaldehyde exposure data. Further, the model is evaluated and improved through optimization of particular parameters to describe formaldehyde-induced respiratory response data and through sensitivity analysis. The model predicts the formaldehyde data well, and hence the model is thought to be a reasonable description of the physiological system of sensory irritation. The model is also expected to translate well to other irritants. JF - Bulletin of mathematical biology AU - Yokley, Karen A AU - Tran, Hien AU - Schlosser, Paul M AD - Center for Research in Scientific Computation and Department of Mathematics, North Carolina State University, Raleigh, NC, USA. yokley.karen@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 555 EP - 588 VL - 70 IS - 2 SN - 0092-8240, 0092-8240 KW - Gases KW - 0 KW - Irritants KW - Formaldehyde KW - 1HG84L3525 KW - Index Medicus KW - Trigeminal Nerve -- physiopathology KW - Animals KW - Hypoventilation -- veterinary KW - Computer Simulation KW - Neuroepithelial Cells -- drug effects KW - Dose-Response Relationship, Drug KW - Neuroepithelial Cells -- physiology KW - Hypoventilation -- physiopathology KW - Feedback, Physiological KW - Respiratory System -- innervation KW - Pulmonary Ventilation -- drug effects KW - Respiratory System -- physiopathology KW - Gases -- toxicity KW - Trigeminal Nerve -- drug effects KW - Rats KW - Inhalation Exposure KW - Hypoventilation -- etiology KW - Formaldehyde -- toxicity KW - Respiratory System -- drug effects KW - Irritants -- toxicity KW - Sensation -- drug effects KW - Respiration -- drug effects KW - Models, Biological KW - Sensation -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70215415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+mathematical+biology&rft.atitle=Sensory+irritation+response+in+rats%3A+modeling%2C+analysis+and+validation.&rft.au=Yokley%2C+Karen+A%3BTran%2C+Hien%3BSchlosser%2C+Paul+M&rft.aulast=Yokley&rft.aufirst=Karen&rft.date=2008-02-01&rft.volume=70&rft.issue=2&rft.spage=555&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+mathematical+biology&rft.issn=00928240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-11 N1 - Date created - 2008-01-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Impact of submersible pumps on Pb constituents in residential wells. AN - 70212306; 17503192 AB - Dissolved Pb in 51 domestic wells screened from 18 to 48 m in glacial tills and outwash deposits were examined in conjunction with the characteristics of their corresponding submersible pump. Pb concentrations, ranging from 0.8 to 24.9 microg l(-1), entering residential water supplies were measured during 2001-2004 in the Royal watershed, Maine. Principal component analyses assisted the weighting of pump age, well screen depth, and draw time variables. Preliminary Pb sequestration significance in the boreholes was predicted from geochemical speciation and synchrotron XAS analyses. Nascent 207Pb/206Pb and 208Pb/206Pb isotope analyses assisted the discrimination of possibly leached Pb from submersible pump materials among geogenic sources. JF - Environmental geochemistry and health AU - Sidle, W C AU - Li, P AD - National Risk Management Research Laboratory, Water Supply & Water Resources Division, U.S. Environmental Protection Agency, 26 West Martin Luther King Blvd, Cincinnati, OH 45268, USA. sidle.william@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 1 EP - 9 VL - 30 IS - 1 SN - 0269-4042, 0269-4042 KW - Isotopes KW - 0 KW - Water Pollutants KW - Lead KW - 2P299V784P KW - Index Medicus KW - Maine KW - Water Supply -- analysis KW - Water Pollutants -- analysis KW - Lead -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70212306?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+geochemistry+and+health&rft.atitle=Impact+of+submersible+pumps+on+Pb+constituents+in+residential+wells.&rft.au=Sidle%2C+W+C%3BLi%2C+P&rft.aulast=Sidle&rft.aufirst=W&rft.date=2008-02-01&rft.volume=30&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Environmental+geochemistry+and+health&rft.issn=02694042&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-24 N1 - Date created - 2008-01-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Chemosphere (Oxford) AN - 50584809; 2008-117943 JF - Chemosphere (Oxford) AU - Solo-Gabriele, Helena M AU - Townsend, Timothy G AU - Khan, Bernine I AU - Dubey, Brajesh AU - Jambeck, Jenna AU - Cai, Yong Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 1930 EP - 1931 PB - Elsevier VL - 70 IS - 10 SN - 0045-6535, 0045-6535 KW - United States KW - toxic materials KW - copper KW - regulations KW - landfills KW - prediction KW - pollution KW - Florida KW - ground water KW - aquifers KW - models KW - arsenates KW - metals KW - chemical properties KW - waste disposal KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50584809?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere+%28Oxford%29&rft.atitle=Chemosphere+%28Oxford%29&rft.au=Solo-Gabriele%2C+Helena+M%3BTownsend%2C+Timothy+G%3BKhan%2C+Bernine+I%3BDubey%2C+Brajesh%3BJambeck%2C+Jenna%3BCai%2C+Yong&rft.aulast=Solo-Gabriele&rft.aufirst=Helena&rft.date=2008-02-01&rft.volume=70&rft.issue=10&rft.spage=1930&rft.isbn=&rft.btitle=&rft.title=Chemosphere+%28Oxford%29&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2007.10.064 L2 - http://www.sciencedirect.com/science/journal/00456535 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 8 N1 - SuppNotes - For reference to original see Saxe, Jennifer K., Wannamaker, Eric J., and Conklin, Scott W., Chemosphere, Vol. 66, No. 3, p. 496-504, 2007 N1 - Last updated - 2012-06-07 N1 - CODEN - CMSHAF N1 - SubjectsTermNotLitGenreText - aquifers; arsenates; chemical properties; copper; Florida; ground water; landfills; metals; models; pollution; prediction; regulations; toxic materials; United States; waste disposal DO - http://dx.doi.org/10.1016/j.chemosphere.2007.10.064 ER - TY - JOUR T1 - Calculation of elapsed decimal time for tracing studies AN - 50583907; 2008-118384 AB - Calculation of time of travel from tracing studies in hydrologic systems is critical to establishing pollutant arrival times from points of inflow to points outflow, calculating subsurface flow velocities, and determining other important transport parameters such as longitudinal dispersion. In addition, breakthrough curve modeling demands accurate time of travel calculations if model results are to have any realistic meaning. However, accurate time of travel calculations are very difficult for long tracer tests in which sampling schedules are not consistent, or when there are major disruptions such as may occur when adverse weather conditions cause automatic sampling equipment to fail. Long and inconsistent sampling times may be accurately converted to decimal times of travel by converting the conventionally recorded Coordinated Universal Time for sampling date and time event to a baseline time standard. By converting to a baseline time standard, all recorded dates and times are linked to the established baseline standard so that each succeeding sampling date and time are correctly determined relative to the previous sampling date and time and to the injection date and time. Abstract Copyright, Journal compilation. JF - Ground Water AU - Field, Malcolm S Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 156 EP - 159 PB - National Ground Water Association, Westerville, OH VL - 46 IS - 1 SN - 0017-467X, 0017-467X KW - concentration KW - monitoring KW - pollutants KW - injection KW - coordinated universal time KW - pollution KW - migration of elements KW - preferential flow KW - measurement KW - ground water KW - aquifers KW - models KW - sampling KW - traveltime KW - tracers KW - velocity KW - breakthrough curves KW - arrival time KW - 21:Hydrogeology KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50583907?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ground+Water&rft.atitle=Calculation+of+elapsed+decimal+time+for+tracing+studies&rft.au=Field%2C+Malcolm+S&rft.aulast=Field&rft.aufirst=Malcolm&rft.date=2008-02-01&rft.volume=46&rft.issue=1&rft.spage=156&rft.isbn=&rft.btitle=&rft.title=Ground+Water&rft.issn=0017467X&rft_id=info:doi/10.1111%2Fj.1745-6584.2007.00400.x LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2016, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 10 N1 - PubXState - OH N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2016-11-17 N1 - CODEN - GRWAAP N1 - SubjectsTermNotLitGenreText - aquifers; arrival time; breakthrough curves; concentration; coordinated universal time; ground water; injection; measurement; migration of elements; models; monitoring; pollutants; pollution; preferential flow; sampling; tracers; traveltime; velocity DO - http://dx.doi.org/10.1111/j.1745-6584.2007.00400.x ER - TY - JOUR T1 - Comparison of (super 85) Kr and (super 3) H apparent ground-water ages for source water vulnerability in the Collyer River catchment, Maine AN - 50542938; 2009-007735 AB - Apparent ground-water ages as determined by the noble gas isotope (super 85) Kr and the water isotope (super 3) H are compared. Refined gas extraction methodology at the wellhead permits efficient collection of Kr for (super 85) Kr isotope enrichment. (super 85) Kr isochrones elucidate areas of much younger ground-water ages than (super 3) H. Declining (super 3) H activities in the catchment prevent its correlation with the youngest measured (super 85) Kr ages. Source water for most drinking water supplies in the Collyer River catchment is recharged within 40 years BP (2004). Mean-age (tau ) transport modeling suggests uncertainty of ground-water ages is greatest in the central basin area. JF - Journal of the American Water Resources Association AU - Sidle, William C Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 14 EP - 26 PB - American Water Resources Association, Middleburg, VA VL - 44 IS - 1 SN - 1093-474X, 1093-474X KW - United States KW - methods KW - isotopes KW - fresh water KW - techniques KW - tritium KW - He-3 KW - drinking water KW - stable isotopes KW - ground water KW - Kr-85 KW - radioactive isotopes KW - noble gases KW - age KW - drainage basins KW - helium KW - Cumberland County Maine KW - krypton KW - Collyer River basin KW - sample preparation KW - recharge KW - hydrogen KW - Maine KW - instruments KW - 21:Hydrogeology KW - 02D:Isotope geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50542938?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Comparison+of+%28super+85%29+Kr+and+%28super+3%29+H+apparent+ground-water+ages+for+source+water+vulnerability+in+the+Collyer+River+catchment%2C+Maine&rft.au=Sidle%2C+William+C&rft.aulast=Sidle&rft.aufirst=William&rft.date=2008-02-01&rft.volume=44&rft.issue=1&rft.spage=14&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2007.00129.x L2 - http://www.wiley.com/bw/journal.asp?ref=1093-474X&site=1 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 42 N1 - PubXState - VA N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - age; Collyer River basin; Cumberland County Maine; drainage basins; drinking water; fresh water; ground water; He-3; helium; hydrogen; instruments; isotopes; Kr-85; krypton; Maine; methods; noble gases; radioactive isotopes; recharge; sample preparation; stable isotopes; techniques; tritium; United States DO - http://dx.doi.org/10.1111/j.1752-1688.2007.00129.x ER - TY - JOUR T1 - Arsenic concentration in the soils of the Brenta Plain (northern Italy); mapping the probability of exceeding contamination thresholds AN - 50509816; 2009-024323 AB - Traditional geochemical mapping is of little help when the uncertainty associated with the estimated values at unsampled locations is required to support decision making. In the Brenta Plain in Northeastern Italy (1350 km (super 2) ), soils are characterized by a pedo-geochemical background value for arsenic which is higher (36 mg kg (super -1) ) than the regulatory threshold (20 mg kg (super -1) ), and it can prove difficult to distinguish between geogenic enrichment and anthropogenic pollution. A simple indicator kriging with varying local means calibrated on the soil map 1:50,000 was used to infer the local conditional cumulative distribution function (ccdf) of As concentration in topsoil (0-40 cm) and subsoil (70-120 cm). The use of local uncertainty models based on the estimated ccdf allowed the assessment of the probabilities to exceed critical thresholds. At the probability levels corresponding to the observed marginal probabilities of values above the regulatory threshold, and using the local background values as reference thresholds, it was found that As concentrations exceed these values at 9 and 7% of the interpolated locations, respectively, for topsoil and subsoil. The computation of the top enrichment factor (TEF), calculated as the ratio between topsoil and subsoil estimated concentrations, and its combination with the probability map of exceeding the usual background value for topsoil, allowed the identification of areas affected by anthropogenic As enrichment, which characterize about 6% of the study area. JF - Journal of Geochemical Exploration AU - Ungaro, F AU - Ragazzi, F AU - Cappellin, R AU - Giandon, P A2 - Bech, Jaume A2 - Bini, Claudio Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 117 EP - 131 PB - Elsevier, Amsterdam-New York VL - 96 IS - 2-3 SN - 0375-6742, 0375-6742 KW - topsoil KW - enrichment KW - kriging KW - mapping KW - Europe KW - alluvial plains KW - environmental analysis KW - Italy KW - Southern Europe KW - geochemical indicators KW - spatial distribution KW - probability KW - chemical composition KW - geochemistry KW - soils KW - pollutants KW - human activity KW - background level KW - statistical analysis KW - arsenic KW - pollution KW - models KW - Brenta Plain KW - soil pollution KW - metals KW - Veneto Italy KW - fluvial features KW - 02C:Geochemistry of rocks, soils, and sediments KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50509816?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geochemical+Exploration&rft.atitle=Arsenic+concentration+in+the+soils+of+the+Brenta+Plain+%28northern+Italy%29%3B+mapping+the+probability+of+exceeding+contamination+thresholds&rft.au=Ungaro%2C+F%3BRagazzi%2C+F%3BCappellin%2C+R%3BGiandon%2C+P&rft.aulast=Ungaro&rft.aufirst=F&rft.date=2008-02-01&rft.volume=96&rft.issue=2-3&rft.spage=117&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geochemical+Exploration&rft.issn=03756742&rft_id=info:doi/10.1016%2Fj.gexplo.2007.03.006 L2 - http://www.sciencedirect.com/science/journal/03756742 LA - English DB - GeoRef N1 - Conference title - International conference on behalf of the European Geosciences Union; session SSS17 "Trace elements in soils; baseline levels and imbalance" N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2009-01-01 N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2012-06-07 N1 - CODEN - JGCEAT N1 - SubjectsTermNotLitGenreText - alluvial plains; arsenic; background level; Brenta Plain; chemical composition; enrichment; environmental analysis; Europe; fluvial features; geochemical indicators; geochemistry; human activity; Italy; kriging; mapping; metals; models; pollutants; pollution; probability; soil pollution; soils; Southern Europe; spatial distribution; statistical analysis; topsoil; Veneto Italy DO - http://dx.doi.org/10.1016/j.gexplo.2007.03.006 ER - TY - JOUR T1 - Predicting estuarine sediment metal concentrations and inferred ecological conditions; an information theoretical approach AN - 50234100; 2009-081427 JF - Journal of Environmental Quality AU - Hollister, Jeffrey W AU - August, Peter V AU - Paul, John E AU - Walker, Henry A Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 234 EP - 244 PB - American Society of Agronomy, [and] Crop Science Society of America, [and] Soil Science Society of America, Madison, WI VL - 37 IS - 1 SN - 0047-2425, 0047-2425 KW - United States KW - numerical models KW - numerical analysis KW - sedimentation KW - pollution KW - Eastern U.S. KW - environmental analysis KW - estuarine sedimentation KW - Atlantic region KW - sediments KW - New England KW - coastal environment KW - ecology KW - estuarine environment KW - heavy metals KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50234100?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Quality&rft.atitle=Predicting+estuarine+sediment+metal+concentrations+and+inferred+ecological+conditions%3B+an+information+theoretical+approach&rft.au=Hollister%2C+Jeffrey+W%3BAugust%2C+Peter+V%3BPaul%2C+John+E%3BWalker%2C+Henry+A&rft.aulast=Hollister&rft.aufirst=Jeffrey&rft.date=2008-02-01&rft.volume=37&rft.issue=1&rft.spage=234&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Quality&rft.issn=00472425&rft_id=info:doi/10.2134%2Fjeq2007.0105 L2 - http://jeq.scijournals.org/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 42 N1 - PubXState - WI N1 - Document feature - illus. incl. 7 tables, sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - JEVQAA N1 - SubjectsTermNotLitGenreText - Atlantic region; coastal environment; Eastern U.S.; ecology; environmental analysis; estuarine environment; estuarine sedimentation; heavy metals; New England; numerical analysis; numerical models; pollution; sedimentation; sediments; United States DO - http://dx.doi.org/10.2134/jeq2007.0105 ER - TY - JOUR T1 - Relationships Among Exceedences of Sediment Guidelines, the Results of Ambient Sediment Toxicity Tests, and Community Metrics in Estuarine Systems AN - 21296978; 11900166 AB - To use bioassessments to help diagnose or identify the specific environmental stressors affecting estuaries, we need a better understanding of the relationships among sediment chemistry guidelines, ambient toxicity tests, and community metrics. However, this relationship is not simple because metrics generally assess the responses at the community level of biological organization whereas sediment guidelines and ambient toxicity tests generally assess or are based on the responses at the organism level. The relationship may be further complicated by the influence of other chemical and physical variables that affect the bioavailability and toxicity of chemical contaminants in the environment. Between 1990 and 1993, the U.S. Environmental Protection Agency (USEPA) conducted an Environmental Monitoring and Assessment Program (EMAP) survey of estuarine sites in the Virginian Province of the eastern United States. The surveys collected data on benthic assemblages, physical and chemical habitat characteristics, and sediment chemistry and toxicity. We characterized these estuarine sites as affected by sediment contamination based on the exceedence of sediment guidelines or on ambient sediment toxicity tests (i.e., 10-day Ampelisca abdita survival). Then, benthic invertebrate metrics were compared among affected and unaffected sites to identify metrics sensitive to the contamination. A number of benthic invertebrate metrics differed between groups of sites segregated using the organism-level measures whereas other metrics did not. The difference among metrics appears to depend on the sensitivity of the individual metrics to the stressor gradient represented by metals or persistent organic toxics in sediments because the insensitive metrics do not effectively quantify the changes in the benthic invertebrate assemblage associated with these stressors. The significant relationships suggest that a relationship exists between the organism-level effects assessed by chemistry or ambient toxicity tests and the community-level effects assessed by community metrics and that the organism-level effects are predictive, to some extent, of community-level effects. JF - Estuaries and Coasts AU - Griffith, Michael B AU - Kravitz, Michael AD - U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, 26 W. Martin Luther King Drive (M.S. A-110), Cincinnati, OH, 45268, USA, griffith.michael@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 101 EP - 114 PB - Estuarine Research Federation, 490 Chippingwood Dr. Port Republic MD 20676-2140 USA VL - 31 IS - 1 SN - 1559-2723, 1559-2723 KW - Toxicology Abstracts; Aqualine Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Pollution Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Oceanic Abstracts KW - toxicity testing KW - Contamination KW - Habitat selection KW - invertebrates KW - ANW, USA, Virginian Province KW - Bioavailability KW - Ampelisca abdita KW - Sediment Contamination KW - Cadmium KW - Testing Procedures KW - Environmental monitoring KW - Sensitivity KW - Metals KW - Sediment chemistry KW - Estuaries KW - Brackish KW - Surveys KW - sediment chemistry KW - Habitat KW - EPA KW - Coastal zone KW - environmental stress KW - Water Pollution Effects KW - Standards KW - survival KW - Contaminants KW - Pollution monitoring KW - Survival KW - Pollution effects KW - Invertebrates KW - Estuarine sedimentation KW - Assessments KW - guidelines KW - Pollutant persistence KW - Chemical pollution KW - Coasts KW - Sediment pollution KW - Data processing KW - Toxicity KW - Sediments KW - Estuarine chemistry KW - USA KW - Zoobenthos KW - Q1 08462:Benthos KW - O 4020:Pollution - Organisms/Ecology/Toxicology KW - P 1000:MARINE POLLUTION KW - Q2 09187:Geochemistry of sediments KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - X 24360:Metals KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21296978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuaries+and+Coasts&rft.atitle=Relationships+Among+Exceedences+of+Sediment+Guidelines%2C+the+Results+of+Ambient+Sediment+Toxicity+Tests%2C+and+Community+Metrics+in+Estuarine+Systems&rft.au=Griffith%2C+Michael+B%3BKravitz%2C+Michael&rft.aulast=Griffith&rft.aufirst=Michael&rft.date=2008-02-01&rft.volume=31&rft.issue=1&rft.spage=101&rft.isbn=&rft.btitle=&rft.title=Estuaries+and+Coasts&rft.issn=15592723&rft_id=info:doi/10.1007%2Fs12237-007-9003-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Sediment pollution; Pollutant persistence; Pollution effects; Estuarine sedimentation; Zoobenthos; Habitat selection; Estuarine chemistry; Environmental monitoring; Sediment chemistry; Metals; Data processing; Contamination; Estuaries; Survival; Toxicity; Habitat; Sediments; Bioavailability; Cadmium; Contaminants; Coasts; toxicity testing; Pollution monitoring; Sensitivity; sediment chemistry; invertebrates; EPA; Coastal zone; guidelines; environmental stress; Chemical pollution; survival; Testing Procedures; Assessments; Water Pollution Effects; Surveys; Sediment Contamination; Standards; Invertebrates; Ampelisca abdita; ANW, USA, Virginian Province; USA; Brackish DO - http://dx.doi.org/10.1007/s12237-007-9003-x ER - TY - JOUR T1 - A Dynamic Model of an Estuarine Invasion by a Non-Native Seagrass AN - 21286124; 11900177 AB - Mathematical and simulation models provide an excellent tool for examining and predicting biological invasions in time and space; however, traditional models do not incorporate dynamic rates of population growth, which limits their realism. We developed a spatially explicit simulation model that allows patch or population growth rate to change with population size through the incorporation of field data. We used the model to evaluate the invasion of a west coast estuary by the non-indigenous Japanese eelgrass, Zostera japonica (Zosteraceae). Specifically, we tested the relative importance of stochastic, abiotic disturbance, interspecific competition, and vegetative and seedling survival. Our model predicted that vegetative shoot and seedling survival limited by competition are the most important limiting factors for Z. japonica growth, although stochastic disturbance was also a limiting factor. Population cycles and patchy distribution were also predicted, with the eelgrass apparently coexisting with the competitor. The model should be applicable to a variety of invasive species, with various types of disturbance and limiting factors. JF - Estuaries and Coasts AU - Almasi, Kama N AU - Eldridge, Peter M AD - U.S. Environmental Protection Agency-Coastal Ecology Branch, WED/CEB, 2111 S.E. Marine Science Drive, Newport, OR, 97365, USA Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 163 EP - 176 PB - Estuarine Research Federation, 490 Chippingwood Dr. Port Republic MD 20676-2140 USA VL - 31 IS - 1 SN - 1559-2723, 1559-2723 KW - Aqualine Abstracts; Ecology Abstracts; Sustainability Science Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Water Resources Abstracts; Oceanic Abstracts KW - population number KW - Population Dynamics KW - Population growth KW - Population dynamics KW - Zosteraceae KW - Marine plants (see also marine algae, seaweeds) KW - Exotic Species KW - shoots KW - disturbance KW - Estuaries KW - Brackish KW - Ecosystem disturbance KW - Model Studies KW - Coastal zone KW - invasions KW - Seedlings KW - Sea grass KW - survival KW - Zostera japonica KW - INW, Japan KW - Survival KW - Models KW - population growth KW - invasive species KW - Coasts KW - Growth rate KW - Seagrasses KW - Mathematical models KW - Simulation KW - Limiting factors KW - Limiting Factors KW - Introduced species KW - Patchiness KW - competition KW - AQ 00001:Water Resources and Supplies KW - Q1 08463:Habitat community studies KW - O 4090:Conservation and Environmental Protection KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - SW 0890:Estuaries KW - Q5 08521:Mechanical and natural changes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21286124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuaries+and+Coasts&rft.atitle=A+Dynamic+Model+of+an+Estuarine+Invasion+by+a+Non-Native+Seagrass&rft.au=Almasi%2C+Kama+N%3BEldridge%2C+Peter+M&rft.aulast=Almasi&rft.aufirst=Kama&rft.date=2008-02-01&rft.volume=31&rft.issue=1&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Estuaries+and+Coasts&rft.issn=15592723&rft_id=info:doi/10.1007%2Fs12237-007-9024-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Growth rate; Mathematical models; Estuaries; Sea grass; Limiting factors; Population dynamics; Introduced species; Patchiness; Ecosystem disturbance; Population growth; Survival; Seedlings; Coasts; Models; population number; disturbance; Seagrasses; Simulation; Coastal zone; population growth; shoots; invasive species; invasions; survival; competition; Marine plants (see also marine algae, seaweeds); Exotic Species; Population Dynamics; Limiting Factors; Model Studies; Zosteraceae; Zostera japonica; INW, Japan; Brackish DO - http://dx.doi.org/10.1007/s12237-007-9024-5 ER - TY - JOUR T1 - Role of Environmental Factors in the Timing of Puberty AN - 21227531; 8041874 AB - Puberty-timing measures have historically been used as indicators of adequate nutrition and growth. More recently, these measures have been examined in relation to exposure to estrogenic or antiandrogenic agents, as well as other environmental factors. The scientific community has debated whether puberty timing is occurring earlier today than in the mid-1900s in the United States and, if so, whether environmental factors play a role; however, no one has asked a multidisciplinary panel to resolve this question. Thus, a multidisciplinary expert panel jointly sponsored by the US Environmental Protection Agency, the National Institute of Environmental Health Sciences, and Serono Symposia International was convened to examine the evidence of a secular trend, identify potential environmental factors of concern, and identify research needs regarding environmental factors and puberty timing at "The Role of Environmental Factors on the Timing and Progression of Puberty" workshop. The majority of the panelists concluded that the girls' data are sufficient to suggest a secular trend toward earlier breast development onset and menarche from 1940 to 1994 but that the boys' data are insufficient to suggest a trend during this same period. The weight-of-the-evidence evaluation of human and animal studies suggest that endocrine-disrupting chemicals, particularly the estrogen mimics and antiandrogens, and body fat are important factors associated in altered puberty timing. A change in the timing of puberty markers was considered adverse from a public health perspective. The panel recommended research areas to further our understanding of the relationships among environmental factors, puberty-timing outcomes, and other reproductive and adult disease at the individual and population levels. JF - Pediatrics AU - Euling, Susan Y AU - Selevan, Sherry G AU - Pescovitz, Ora Hirsch AU - Skakkebaek, Niels E AD - National Center for Environmental Assessment, Office of Research and Development, US Environmental Protection Agency, Washington, DC. Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana. University Department of Growth and Reproduction, Rigshospitalet, Blegdamsvej, Copenhagen, Denmark Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - S167 EP - S171 PB - American Academy of Pediatrics, 141 Northwest Point Blvd. Elk Grove Village IL 60007-1098 USA, [mailto:journals@aap.org], [URL:http://www.aap.org] VL - 121 IS - Supplement_3 SN - 0031-4005, 0031-4005 KW - Health & Safety Science Abstracts KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21227531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatrics&rft.atitle=Role+of+Environmental+Factors+in+the+Timing+of+Puberty&rft.au=Euling%2C+Susan+Y%3BSelevan%2C+Sherry+G%3BPescovitz%2C+Ora+Hirsch%3BSkakkebaek%2C+Niels+E&rft.aulast=Euling&rft.aufirst=Susan&rft.date=2008-02-01&rft.volume=121&rft.issue=Supplement_3&rft.spage=S167&rft.isbn=&rft.btitle=&rft.title=Pediatrics&rft.issn=00314005&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Reproductive Toxicity of Vinclozolin in the Fathead Minnow: Confirming An Anti-Androgenic Mode of Action AN - 20846841; 8031519 AB - The objective of the present study was to characterize responses of the reproductive endocrine system of the fathead minnow (Pimephales promelas) to the fungicide vinclozolin (VZ), using a 21-d reproduction assay, and a shorter-term (approximately two weeks) test in which fish were cotreated with the VZ (a putative anti-androgen) and the androgen 17 beta -trenbolone (TB). Effects on fecundity, gonadal histology, secondary sexual characteristics, reproductive hormones, and relative abundance of androgen receptor (AR) and 11 beta -hydroxysteroid dehydrogenase (11 beta HSD) mRNA transcripts were evaluated in one or both of these studies. Fecundity of VZ-exposed fish was decreased in a concentration-dependent manner in the 21-d test, culminating in complete reproductive failure at a concentration of 700 mu g/L. Exposure to VZ decreased expression of male secondary sexual characteristics- an effect typical of anti-androgens. The finding that exposure of females to TB-induced expression of prominent, male-like tubercles, which could be effectively blocked with VZ, provides powerful evidence of the anti-androgenic activity of VZ in vivo. In the two experiments VZ produced several responses possibly indicative of compensation or adaptation of the fish to the anti-androgen, including increases in gonad weight, AR and 11 beta HSD mRNA transcript abundance, and ex vivo gonadal production of testosterone and 11- ketotestosterone. Overall, our results demonstrate that the model anti- androgen VZ, which also is an environmental contaminant, impairs reproductive success of fathead minnows and elicits endocrine responses consistent with an anti-androgenic mode of action. JF - Environmental Toxicology and Chemistry AU - Martinovicacute, Dalma AU - Blake, Lindsey S AU - Durhan, Elizabeth J AU - Greene, Katie J AU - Kahl, Michael D AU - Jensen, Kathleen M AU - Makynen, Elizabeth A AU - Villeneuve, Daniel L AU - Ankley, Gerald T AD - Mid-Continent Ecology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, 6201 Congdon Boulevard, Duluth, Minnesota 55804 Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 478 EP - 488 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 27 IS - 2 SN - 0730-7268, 0730-7268 KW - Biochemistry Abstracts 2: Nucleic Acids; Pollution Abstracts; Toxicology Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Fish KW - Vinclozolin KW - Anti-androgen KW - Endocrine disruption KW - Reproduction KW - Abundance KW - Freshwater fish KW - Hormones KW - Toxicity tests KW - Sex hormones KW - 11 beta -Hydroxysteroid dehydrogenase KW - Exposure KW - Assay KW - Endocrine system KW - Pollution indicators KW - Testing Procedures KW - Fathead Minnows KW - Sexual Reproduction KW - Testosterone KW - Fecundity KW - Fish physiology KW - Endocrinology KW - Contaminants KW - abundance KW - Reproductive failure KW - Models KW - fecundity KW - Pollutants KW - gonads KW - Mode of Action KW - Adaptations KW - relative abundance KW - Toxicity KW - Androgen receptors KW - Pimephales promelas KW - Histology KW - Fungicides KW - Gonads KW - Androgens KW - Breeding success KW - Q5 08504:Effects on organisms KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - N 14830:RNA KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20846841?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=Reproductive+Toxicity+of+Vinclozolin+in+the+Fathead+Minnow%3A+Confirming+An+Anti-Androgenic+Mode+of+Action&rft.au=Martinovicacute%2C+Dalma%3BBlake%2C+Lindsey+S%3BDurhan%2C+Elizabeth+J%3BGreene%2C+Katie+J%3BKahl%2C+Michael+D%3BJensen%2C+Kathleen+M%3BMakynen%2C+Elizabeth+A%3BVilleneuve%2C+Daniel+L%3BAnkley%2C+Gerald+T&rft.aulast=Martinovicacute&rft.aufirst=Dalma&rft.date=2008-02-01&rft.volume=27&rft.issue=2&rft.spage=478&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F07-206R.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Fecundity; Fish physiology; Endocrinology; Fungicides; Reproduction; Freshwater fish; Pollution indicators; Toxicity tests; Sex hormones; Adaptations; Vinclozolin; Reproductive failure; Abundance; Toxicity; Hormones; Models; Androgen receptors; 11 beta -Hydroxysteroid dehydrogenase; Testosterone; Gonads; Endocrine system; Contaminants; Breeding success; Androgens; fecundity; gonads; Histology; relative abundance; abundance; Testing Procedures; Mode of Action; Pollutants; Exposure; Assay; Fathead Minnows; Fish; Sexual Reproduction; Pimephales promelas DO - http://dx.doi.org/10.1897/07-206R.1 ER - TY - JOUR T1 - Observable indicators of the sensitivity of PM sub(2) sub(.) sub(5) nitrate to emission reductions-Part I: Derivation of the adjusted gas ratio and applicability at regulatory-relevant time scales AN - 20690725; 8184275 AB - Chemical transport models have frequently been used to evaluate the impacts of emission reductions on inorganic PM sub(2) sub(.) sub(5). However, such models are limited in their accuracy by uncertain estimates of the spatial and temporal characterization of emissions and meteorology. Site-specific observations can more accurately characterize the distribution of pollutants, but cannot predict the effectiveness of emission controls. In this research, we use equilibrium theory and a chemical transport model to find observable indicators that are robust predictors of the change in PM sub(2) sub(.) sub(5) nitrate due to changes in NH sub(3), SO sub(2), and NO sub(x) emissions. Two conditions are necessary: (1) the indicator must be valid at both instantaneous equilibrium and regulatory (daily and monthly) time-scales and (2) the indicator must be able to explain the majority of the spatial and temporal variance in the PM sub(2) sub(.) sub(5) nitrate sensitivity. We find that the ratio of free ammonia to total nitrate meets these conditions during the winter in the Eastern United States. This observable ratio can be used to predict the percent change in PM sub(2) sub(.) sub(5) nitrate due to SO sub(2) and NH sub(3) emissions reductions with nearly zero bias when compared with an emission driven chemical transport model. This permits a novel method for estimating the effectiveness of emission control strategies. The chemical transport model can be used to derive the relationship between the observed concentrations and the change in nitrate due to emission changes. Then observations can be used to apply that relationship to specific locations of interest. JF - Atmospheric Environment AU - Pinder, R W AU - Dennis, R L AU - Bhave, P V AD - Air Resources Laboratory, National Oceanic and Atmospheric Administration, US EPA Mail Drop E243-01, Research Triangle Park, NC 27711, USA, pinder.rob@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 1275 EP - 1286 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 6 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Particle size KW - Atmospheric pollution models KW - Atmospheric pollution KW - Particulate air pollutants KW - Nitrates KW - Ammonia KW - Ammonia content of atmosphere KW - Emission control KW - USA KW - Sulfur dioxide KW - winter KW - Emissions KW - Meteorology KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20690725?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Observable+indicators+of+the+sensitivity+of+PM+sub%282%29+sub%28.%29+sub%285%29+nitrate+to+emission+reductions-Part+I%3A+Derivation+of+the+adjusted+gas+ratio+and+applicability+at+regulatory-relevant+time+scales&rft.au=Pinder%2C+R+W%3BDennis%2C+R+L%3BBhave%2C+P+V&rft.aulast=Pinder&rft.aufirst=R&rft.date=2008-02-01&rft.volume=42&rft.issue=6&rft.spage=1275&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.10.039 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Particulate air pollutants; Atmospheric pollution; Atmospheric pollution models; Ammonia content of atmosphere; Meteorology; Particle size; winter; Sulfur dioxide; Nitrates; Ammonia; Emissions; Emission control; USA DO - http://dx.doi.org/10.1016/j.atmosenv.2007.10.039 ER - TY - JOUR T1 - Observable indicators of the sensitivity of PM sub(2) sub(.) sub(5) nitrate to emission reductions-Part II: Sensitivity to errors in total ammonia and total nitrate of the CMAQ-predicted non-linear effect of SO sub(2) emission reductions AN - 20688958; 8184274 AB - The inorganic aerosol system of sulfate, nitrate, and ammonium can respond non-linearly to changes in precursor sulfur dioxide (SO sub(2)) emissions. The potential increase in nitrate, when sulfate is reduced and the associated ammonia is released, can negate the sulfate mass reduction. Current regional-scale air quality models do not reproduce the present-day levels of total ammonia and total nitrate, leading to possible errors in the air quality model predictions of future nitrate concentrations. The objective of this study is to quantify the effects of errors in the total-ammonia and total-nitrate budgets on nitrate relative response (RR), defined as the percent change in particulate nitrate stemming from reductions in SO sub(2) emissions. This objective is addressed through three sensitivity studies using the Community Multiscale Air Quality model (CMAQ). These studies assess the sensitivity of the nitrate RR (%) to (1) errors in ammonia emissions, (2) errors in the heterogeneous production of nitrate from N sub(2)O sub(5), and (3) errors in the NO sub(X) emissions. The results indicate that nitrate RRs due to SO sub(2) emission reductions are much more sensitive to errors in the total-ammonia budget than to errors in the total-nitrate budget. The sensitivity of the nitrate RR to NO sub(X) emissions is only moderate and is due primarily to the effect of NO sub(X) changes on sulfate production, rather than on total nitrate. Also, a strong relationship was found between the nitrate RR and the Adjusted Gas Ratio (free ammonia adjusted for the degree of sulfate neutralization divided by total nitrate). JF - Atmospheric Environment AU - Dennis, R L AU - Bhave, P V AU - Pinder, R W AD - Atmospheric Sciences Modeling Division, National Oceanic and Atmospheric Administration, US EPA Mail Drop E243-01, Research Triangle Park, NC 27711, USA, Robin.Dennis@noaa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 1287 EP - 1300 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 42 IS - 6 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Sulfates KW - Sulfur in aerosols KW - Air quality KW - Particulates KW - Sulfur dioxide KW - Ammonia emissions KW - Emissions KW - Neutralization KW - budgets KW - Particle size KW - Ammonium KW - Aerosols KW - Atmospheric pollution KW - Nitrates KW - Sulfur emissions KW - Ammonia KW - Ammonia content of atmosphere KW - Emission control KW - Air quality models KW - Particulate matter emissions KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20688958?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Observable+indicators+of+the+sensitivity+of+PM+sub%282%29+sub%28.%29+sub%285%29+nitrate+to+emission+reductions-Part+II%3A+Sensitivity+to+errors+in+total+ammonia+and+total+nitrate+of+the+CMAQ-predicted+non-linear+effect+of+SO+sub%282%29+emission+reductions&rft.au=Dennis%2C+R+L%3BBhave%2C+P+V%3BPinder%2C+R+W&rft.aulast=Dennis&rft.aufirst=R&rft.date=2008-02-01&rft.volume=42&rft.issue=6&rft.spage=1287&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.10.036 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Sulfur in aerosols; Atmospheric pollution; Sulfur emissions; Particulate matter emissions; Ammonia emissions; Ammonia content of atmosphere; Air quality models; Sulfates; Particle size; Ammonium; Aerosols; Nitrates; Ammonia; Air quality; Emission control; Particulates; Sulfur dioxide; Emissions; budgets; Neutralization DO - http://dx.doi.org/10.1016/j.atmosenv.2007.10.036 ER - TY - JOUR T1 - Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites AN - 20629813; 8169358 AB - A physiologically-based pharmacokinetic (PBPK) model was developed to estimate levels of arsenic and its metabolites in human tissues and urine after oral exposure to arsenate (As super(V)), arsenite (As super(III)) or organoarsenical pesticides. The model consists of interconnected individual PBPK models for inorganic arsenic (As super(V) and As super(III)), monomethylarsenic acid (MMA super(V)), and, dimethylarsenic acid (DMA super(V)). Reduction of MMA super(V) and DMA super(V) to their respective trivalent forms also occurs in the lung, liver, and kidney including excretion in urine. Each submodel was constructed using flow limited compartments describing the mass balance of the chemicals in GI tract (lumen and tissue), lung, liver, kidney, muscle, skin, heart, and brain. The choice of tissues was based on physiochemical properties of the arsenicals (solubility), exposure routes, target tissues, and sites for metabolism. Metabolism of inorganic arsenic in liver was described as a series of reduction and oxidative methylation steps incorporating the inhibitory influence of metabolites on methylation. The inhibitory effects of As super(III) on the methylation of MMA super(III) to DMA, and MMA super(III) on the methylation of As super(III) to MMA were modeled as noncompetitive. To avoid the uncertainty inherent in estimation of many parameters from limited human data, a priori independent parameter estimates were derived using data from diverse experimental systems with priority given to data derived using human cells and tissues. This allowed the limited data for human excretion of arsenicals in urine to be used to estimate only parameters that were most sensitive to this type of data. Recently published urinary excretion data, not previously used in model development, are also used to evaluate model predictions. JF - Journal of Pharmacokinetics and Biopharmaceutics AU - El-Masri, Hisham A AU - Kenyon, Elaina M AD - U. S. Environmental Protection Agency, MD-B143-01, Research Triangle Park, NC, 27711, USA, el-masri.hisham@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 31 EP - 68 PB - Springer New York LLC VL - 35 IS - 1 SN - 1567-567X, 1567-567X KW - Toxicology Abstracts KW - Arsenic KW - Solubility KW - Skin KW - Brain KW - Muscles KW - Arsenite KW - Cardiac muscle KW - Metabolites KW - Development KW - Pharmacokinetics KW - Lung KW - Urine KW - Pesticides KW - Kidney KW - Liver KW - Excretion KW - Gastrointestinal tract KW - Methylation KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20629813?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Pharmacokinetics+and+Biopharmaceutics&rft.atitle=Development+of+a+human+physiologically+based+pharmacokinetic+%28PBPK%29+model+for+inorganic+arsenic+and+its+mono-+and+di-methylated+metabolites&rft.au=El-Masri%2C+Hisham+A%3BKenyon%2C+Elaina+M&rft.aulast=El-Masri&rft.aufirst=Hisham&rft.date=2008-02-01&rft.volume=35&rft.issue=1&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Journal+of+Pharmacokinetics+and+Biopharmaceutics&rft.issn=1567567X&rft_id=info:doi/10.1007%2Fs10928-007-9075-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Arsenic; Skin; Solubility; Arsenite; Muscles; Brain; Cardiac muscle; Metabolites; Development; Pharmacokinetics; Urine; Lung; Pesticides; Liver; Kidney; Excretion; Gastrointestinal tract; Methylation DO - http://dx.doi.org/10.1007/s10928-007-9075-z ER - TY - JOUR T1 - The relationship of maternal and fetal toxicity in developmental toxicology bioassays with notes on the biological significance of the ''no observed adverse effect level'' AN - 20600713; 8103558 AB - Standard developmental toxicology bioassays are designed to identify agents with the potential to induce adverse effects and include dose levels that induce maternal toxicity. The work reported here was undertaken to evaluate the relationship of maternal and fetal toxicity. It constitutes an analysis of 125 developmental toxicity bioassays in the mouse, rat, and rabbit conducted by the National Toxicology Program. Although varying by species, general findings include: (1) most lowest observable adverse effect levels (LOAELs) were determined by reduced maternal gestational weight gain or fetal weight at term. (2) Maternal weight reductions are associated with reduced food intake for a variety of dissimilar test agents. (3) Lower fetal weights were associated with reduced maternal weight gains late in gestation. (4) The degree of fetal weight reduction is correlated with the extent of the maternal weight loss. In a substantial number of the studies, reduced fetal weights at term may, therefore, be due to maternal undernutrition caused by general toxicity rather than direct developmental insult. Consequently, such test agents may be erroneously classified as primary developmental toxicants. Experimental approaches to test the hypothesis that maternal undernutrition in standard developmental toxicology bioassays may be responsible for significant term fetal weight decrements are discussed. JF - Reproductive Toxicology AU - Chernoff, N AU - Rogers, E H AU - Gage, MI AU - Francis, B M AD - ORD, National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC 27711, USA, chernoff.neil@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 192 EP - 202 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 25 IS - 2 SN - 0890-6238, 0890-6238 KW - Health & Safety Science Abstracts; Toxicology Abstracts KW - Undernutrition KW - Toxicants KW - Toxicity KW - Fetuses KW - Body weight loss KW - Bioassays KW - Body weight KW - Food intake KW - Gestation KW - Body weight gain KW - Side effects KW - H 14000:Toxicology KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20600713?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reproductive+Toxicology&rft.atitle=The+relationship+of+maternal+and+fetal+toxicity+in+developmental+toxicology+bioassays+with+notes+on+the+biological+significance+of+the+%27%27no+observed+adverse+effect+level%27%27&rft.au=Chernoff%2C+N%3BRogers%2C+E+H%3BGage%2C+MI%3BFrancis%2C+B+M&rft.aulast=Chernoff&rft.aufirst=N&rft.date=2008-02-01&rft.volume=25&rft.issue=2&rft.spage=192&rft.isbn=&rft.btitle=&rft.title=Reproductive+Toxicology&rft.issn=08906238&rft_id=info:doi/10.1016%2Fj.reprotox.2007.12.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Body weight loss; Undernutrition; Toxicants; Food intake; Gestation; Toxicity; Body weight gain; Side effects; Fetuses; Bioassays; Body weight DO - http://dx.doi.org/10.1016/j.reprotox.2007.12.001 ER - TY - JOUR T1 - Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener AN - 20542146; 8091857 AB - Polybrominated diphenyl ethers (PBDEs) are a class of polyhalogenated aromatic compounds commercially used as fire retardants in consumer products. These compounds have been shown to decrease thyroid hormone concentrations in rodents after acute exposures. This study examines the ability of 2,2',4,4'-tetrabromodiphenyl ether (BDE 47) to decrease circulating thyroid hormone concentrations and pairs this with BDE 47-induced effects on genes involved in thyroid hormone homeostasis. Female C57BL/6 mice (9 weeks old) were orally administered 3, 10, or 100 mg/kg/day of BDE 47 for 4 days. Animals were euthanized 24 h after the final dose (day 5) and liver, kidney, and serum were collected for analysis. BDE 47 caused a significant 43% decrease at 100 mg/kg/day in serum total thyroxine (T sub(4)) concentrations. There was no increase in hepatic T sub(4)-glucuronidation activity, but significant increases in hepatic Ugt1a1, Ugt1a7, and Ugt2b5 mRNA expression accompany significant decreases in T sub(4) concentrations at 100 mg/kg/day of BDE 47. Induction of PROD activity occurred at the lowest dose (3 mg/kg /day). Cyp2b10 mRNA expression also increased significantly at 10 and 100 mg/kg/day. These key findings show that BDE activates the nuclear receptor, CAR. Decreases in Mdr1a mRNA expression also occurred at the lowest dose administered (3 mg/kg/day BDE 47). BDE 47 exposure also decreased hepatic transthyretin and monocarboxylate transporter 8 (Mct8) mRNA expression, suggesting that while induction of UGTs may be partly responsible for T sub(4) decreases, other mechanisms are also involved. No effects were seen in the kidney. We conclude that changes in hepatic UGTs and transporters may be involved in decreases in circulating T sub(4) following BDE 47 exposure. JF - Toxicology and Applied Pharmacology AU - Richardson, V M AU - Staskal, D F AU - Ross, D G AU - Diliberto, J J AU - DeVito, MJ AU - Birnbaum, L S AD - ORD, NHEERL, ETD 109 TW Alexander Dr. MD B143-01 Research Triangle Park, NC 27711, USA, richardson.vicki@epa.gov Y1 - 2008/02/01/ PY - 2008 DA - 2008 Feb 01 SP - 244 EP - 250 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 226 IS - 3 SN - 0041-008X, 0041-008X KW - Toxicology Abstracts KW - Fires KW - transthyretin KW - Nuclear receptors KW - Oral administration KW - Homeostasis KW - Gene expression KW - Thyroid hormones KW - polybrominated diphenyl ethers KW - Aromatic compounds KW - Kidney KW - Liver KW - Thyroxine KW - Congeners KW - Multidrug resistance KW - Consumers KW - Ethers KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20542146?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Possible+mechanisms+of+thyroid+hormone+disruption+in+mice+by+BDE+47%2C+a+major+polybrominated+diphenyl+ether+congener&rft.au=Richardson%2C+V+M%3BStaskal%2C+D+F%3BRoss%2C+D+G%3BDiliberto%2C+J+J%3BDeVito%2C+MJ%3BBirnbaum%2C+L+S&rft.aulast=Richardson&rft.aufirst=V&rft.date=2008-02-01&rft.volume=226&rft.issue=3&rft.spage=244&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.09.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Fires; transthyretin; Nuclear receptors; Oral administration; Homeostasis; Gene expression; Thyroid hormones; polybrominated diphenyl ethers; Aromatic compounds; Thyroxine; Liver; Kidney; Congeners; Consumers; Multidrug resistance; Ethers DO - http://dx.doi.org/10.1016/j.taap.2007.09.015 ER - TY - JOUR T1 - Iron Homeostasis in the Lung Following Asbestos Exposure AN - 20474612; 8011958 AB - Human exposure to asbestos can cause a wide variety of pulmonary diseases, including pneumoconiosis (i.e., asbestosis). This lung injury is mediated by oxidant generation which increases with the concentration of iron associated with the asbestos. Iron from host sources is complexed by the surface of these fibrous silicates following introduction into the lower respiratory tract. Using bronchoalveolar lavage from unexposed and exposed workers, we demonstrate that asbestos disrupts the normal iron homeostasis in the lungs. Based on these findings, we propose a model of oxidative stress and human lung injury after asbestos exposure. JF - Antioxidants and Redox Signaling AU - Ghio, A J AU - Stonehuerner, J AU - Richards, J AU - Devlin, R B AD - HSD, NHEERL, USEPA Campus Box 7315 104 Mason Farm Road Chapel Hill, North Carolina 27599-7315, USA, ghio.andy@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 371 EP - 377 VL - 10 IS - 2 SN - 1523-0864, 1523-0864 KW - Toxicology Abstracts KW - Asbestos KW - Antioxidants KW - Injuries KW - Silicic acid KW - Lung diseases KW - Pneumoconiosis KW - Homeostasis KW - Asbestosis KW - Alveoli KW - Models KW - Bronchus KW - Oxidative stress KW - Iron KW - Oxidants KW - Signal transduction KW - Respiratory tract KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20474612?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antioxidants+and+Redox+Signaling&rft.atitle=Iron+Homeostasis+in+the+Lung+Following+Asbestos+Exposure&rft.au=Ghio%2C+A+J%3BStonehuerner%2C+J%3BRichards%2C+J%3BDevlin%2C+R+B&rft.aulast=Ghio&rft.aufirst=A&rft.date=2008-02-01&rft.volume=10&rft.issue=2&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Antioxidants+and+Redox+Signaling&rft.issn=15230864&rft_id=info:doi/10.1089%2Fars.2007.1909 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Asbestos; Antioxidants; Injuries; Silicic acid; Pneumoconiosis; Lung diseases; Homeostasis; Alveoli; Asbestosis; Models; Bronchus; Oxidative stress; Iron; Oxidants; Respiratory tract; Signal transduction DO - http://dx.doi.org/10.1089/ars.2007.1909 ER - TY - JOUR T1 - A Hierarchical Clustering Methodology for the Estimation of Toxicity AN - 20275010; 8883065 AB - A quantitative structure-activity relationship (QSAR) methodology based on hierarchical clustering was developed to predict toxicological endpoints. This methodology utilizes Ward's method to divide a training set into a series of structurally similar clusters. The structural similarity is defined in terms of 2-D physicochemical descriptors (such as connectivity and E-state indices). A genetic algorithm-based technique is used to generate statistically valid QSAR models for each cluster (using the pool of descriptors described above). The toxicity for a given query compound is estimated using the weighted average of the predictions from the closest cluster from each step in the hierarchical clustering assuming that the compound is within the domain of applicability of the cluster. The hierarchical clustering methodology was tested using a Tetrahymena pyriformis acute toxicity data set containing 644 chemicals in the training set and with two prediction sets containing 339 and 110 chemicals. The results from the hierarchical clustering methodology were compared to the results from several different QSAR methodologies. JF - Toxicology Mechanisms and Methods AU - Martin, Todd M AU - Harten, Paul AU - Venkatapathy, Raghuraman AU - Das, Shashikala AU - Young, Douglas M AD - Sustainable Technology Division, National Risk Management Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Cincinnati, OH, USA Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 251 EP - 266 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 18 IS - 2-3 SN - 1537-6516, 1537-6516 KW - Toxicology Abstracts KW - Data processing KW - Tetrahymena pyriformis KW - Statistical analysis KW - Acute toxicity KW - Structure-activity relationships KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20275010?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+Mechanisms+and+Methods&rft.atitle=A+Hierarchical+Clustering+Methodology+for+the+Estimation+of+Toxicity&rft.au=Martin%2C+Todd+M%3BHarten%2C+Paul%3BVenkatapathy%2C+Raghuraman%3BDas%2C+Shashikala%3BYoung%2C+Douglas+M&rft.aulast=Martin&rft.aufirst=Todd&rft.date=2008-02-01&rft.volume=18&rft.issue=2-3&rft.spage=251&rft.isbn=&rft.btitle=&rft.title=Toxicology+Mechanisms+and+Methods&rft.issn=15376516&rft_id=info:doi/10.1080%2F15376510701857353 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Data processing; Statistical analysis; Acute toxicity; Structure-activity relationships; Tetrahymena pyriformis DO - http://dx.doi.org/10.1080/15376510701857353 ER - TY - JOUR T1 - Toxicity Data Informatics: Supporting a New Paradigm for Toxicity Prediction AN - 20250344; 8883054 AB - Chemical toxicity data at all levels of description, from treatment-level dose response data to a high-level summarized toxicity 'endpoint,' effectively circumscribe, enable, and limit predictive toxicology approaches and capabilities. Several new and evolving public data initiatives focused on the world of chemical toxicity information -as represented here by ToxML (Toxicology XML standard), DSSTox (Distributed Structure-Searchable Toxicity Database Network), and ACToR (Aggregated Computational Toxicology Resource) -are contributing to the creation of a more unified, mineable, and modelable landscape of public toxicity data. These projects address different layers in the spectrum of toxicological data representation and detail and, additionally, span diverse domains of toxicology and chemistry in relation to industry and environmental regulatory concerns. For each of the three projects, data standards are the key to enabling 'read-across' in relation to toxicity data and chemical-indexed information. In turn, 'read-across' capability enables flexible data mining, as well as meaningful aggregation of lower levels of toxicity information to summarized, modelable endpoints spanning sufficient areas of chemical space for building predictive models. By means of shared data standards and transparent and flexible rules for data aggregation, these and related public data initiatives are effectively spanning the divides among experimental toxicologists, computational modelers, and the world of chemically indexed, publicly available toxicity information. JF - Toxicology Mechanisms and Methods AU - Richard, Ann M AU - Yang, Chihae AU - Judson, Richard S AD - National Center for Computational Toxicology, U.S. Environmental Protection Agency, Research Triangle Park, NC Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 103 EP - 118 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 18 IS - 2-3 SN - 1537-6516, 1537-6516 KW - Toxicology Abstracts KW - Databases KW - Computer programs KW - Data processing KW - Informatics KW - Landscape KW - Toxicity KW - Computer applications KW - Models KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20250344?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+Mechanisms+and+Methods&rft.atitle=Toxicity+Data+Informatics%3A+Supporting+a+New+Paradigm+for+Toxicity+Prediction&rft.au=Richard%2C+Ann+M%3BYang%2C+Chihae%3BJudson%2C+Richard+S&rft.aulast=Richard&rft.aufirst=Ann&rft.date=2008-02-01&rft.volume=18&rft.issue=2-3&rft.spage=103&rft.isbn=&rft.btitle=&rft.title=Toxicology+Mechanisms+and+Methods&rft.issn=15376516&rft_id=info:doi/10.1080%2F15376510701857452 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Computer programs; Databases; Data processing; Informatics; Landscape; Toxicity; Computer applications; Models DO - http://dx.doi.org/10.1080/15376510701857452 ER - TY - JOUR T1 - Effects of low dissolved oxygen on organisms used in freshwater sediment toxicity tests AN - 20203438; 8098903 AB - Minimum dissolved oxygen requirements are part of standard guidelines for toxicity testing of freshwater sediments with several benthic invertebrates, but the data underlying these requirements are somewhat sparse. We exposed three common test organisms to ranges of dissolved oxygen concentrations to determine their responses in 10-d exposures, relative to published guidelines for sediment toxicity tests. The oligochaete, Lumbriculus variegatus, showed 100% survival in all exposures down to the lowest concentration tested, 0.7mg O sub(2)l super(-) super(1). Midge (Chironomus dilutus) larva showed a more pronounced response; while survival was less than 90% only below 1.0mg O sub(2)l super(-) super(1), the biomass endpoint showed EC sub(5) sub(0), EC sub(2) sub(0), and EC sub(1) sub(0) values of 1.00 (0.91-1.10), 1.41 (1.16-1.71), and 1.67 (1.25-2.24) mg O sub(2)l super(-) super(1). The amphipod, Hyalella azteca, showed no adverse effects at concentrations as low as 2.12mg O sub(2)l super(-) super(1). The combination of these data with other literature data suggest that DO minima in current North American 10-d sediment test guidelines are reasonable. JF - Chemosphere AU - Mattson, V R AU - Russell Hockett, J AU - Highland, T L AU - Ankley, G T AU - Mount AD - Office of Research and Development, National Health and Environmental Effects Laboratory, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, MN 55804, USA, mount.dave@epa.gov Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 1840 EP - 1844 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 70 IS - 10 SN - 0045-6535, 0045-6535 KW - Pollution Abstracts; Aqualine Abstracts; Entomology Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Oligochaetes KW - toxicity testing KW - Toxicity tests KW - invertebrates KW - Dissolved oxygen KW - Exposure KW - Sediment Contamination KW - Pollution indicators KW - Testing Procedures KW - North America KW - Sediment chemistry KW - test organisms KW - Freshwater environments KW - Test organisms KW - Biomass KW - Inland water environment KW - Chironomus KW - Standards KW - survival KW - Toxicity testing KW - Survival KW - Oligochaeta KW - guidelines KW - Sediment pollution KW - Amphipods KW - Dissolved Oxygen KW - Toxicity KW - Sediments KW - Hyalella azteca KW - Lumbriculus variegatus KW - Bioaccumulation KW - Zoobenthos KW - Side effects KW - Q5 08503:Characteristics, behavior and fate KW - Q1 08462:Benthos KW - Q2 09264:Sediments and sedimentation KW - Z 05320:Physiology, Anatomy, and Biochemistry KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20203438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Effects+of+low+dissolved+oxygen+on+organisms+used+in+freshwater+sediment+toxicity+tests&rft.au=Mattson%2C+V+R%3BRussell+Hockett%2C+J%3BHighland%2C+T+L%3BAnkley%2C+G+T%3BMount&rft.aulast=Mattson&rft.aufirst=V&rft.date=2008-02-01&rft.volume=70&rft.issue=10&rft.spage=1840&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2007.08.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Sediment chemistry; Sediment pollution; Bioaccumulation; Test organisms; Zoobenthos; Inland water environment; Pollution indicators; Toxicity tests; Dissolved oxygen; Freshwater environments; Survival; Toxicity; Biomass; Toxicity testing; Side effects; Sediments; toxicity testing; test organisms; guidelines; survival; invertebrates; Oligochaetes; Testing Procedures; Amphipods; Exposure; Dissolved Oxygen; Sediment Contamination; Standards; Hyalella azteca; Lumbriculus variegatus; Chironomus; Oligochaeta; North America DO - http://dx.doi.org/10.1016/j.chemosphere.2007.08.006 ER - TY - JOUR T1 - Bifidobacteria in Feces and Environmental Waters AN - 19996329; 8032712 AB - Bifidobacteria have been recommended as potential indicators of human fecal pollution in surface waters even though very little is known about their presence in nonhuman fecal sources. The objective of this research was to shed light on the occurrence and molecular diversity of this fecal indicator group in different animals and environmental waters. Genus- and species-specific 16S rRNA gene PCR assays were used to study the presence of bifidobacteria among 269 fecal DNA extracts from 32 different animals. Twelve samples from three wastewater treatment plants and 34 water samples from two fecally impacted watersheds were also tested. The species-specific assays showed that Bifidobacterium adolescentis, B. bifidum, B. dentium, and B. catenulatum had the broadest host distribution (11.9 to 17.4%), whereas B. breve, B. infantis, and B. longum were detected in fewer than 3% of all fecal samples. Phylogenetic analysis of 356 bifidobacterial clones obtained from different animal feces showed that ca. 67% of all of the sequences clustered with cultured bifidobacteria, while the rest formed a supercluster with low sequence identity (i.e., 97% similarity) contained 53 fecal sequences from seven different animal hosts, suggesting the cosmopolitan distribution of members of this clade. In contrast, two clades containing B. thermophilum and B. boum clustered exclusively with 37 and 18 pig fecal clones, respectively, suggesting host specificity. Using species-specific assays, bifidobacteria were detected in only two of the surface water DNA extracts, although other fecal anaerobic bacteria were detected in these waters. Overall, the results suggest that the use of bifidobacterial species as potential markers to monitor human fecal pollution in natural waters may be questionable. JF - Applied and Environmental Microbiology AU - Lamendella, Regina AU - Domingo, Jorge WSanto AU - Kelty, Catherine AU - Oerther, Daniel B AD - Department of Environmental Engineering, University of Cincinnati, Cincinnati, Ohio 45220. U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, 26 Martin Luther King Drive, MS-387, Cincinnati, Ohio 45268 Y1 - 2008/02/01/ PY - 2008 DA - 2008 Feb 01 SP - 575 EP - 584 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 74 IS - 3 SN - 0099-2240, 0099-2240 KW - Pollution Abstracts; Ecology Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology; Water Resources Abstracts KW - Water sampling KW - Water Analysis KW - Surface water KW - Indicators KW - Surface Water KW - Watersheds KW - Wastewater treatment KW - Assay KW - Polymerase chain reaction KW - Feces KW - Pollution KW - Anaerobic bacteria KW - Phylogeny KW - Host specificity KW - Fecal coliforms KW - Bifidobacterium adolescentis KW - Anaerobic Bacteria KW - Natural Waters KW - Microorganisms KW - DNA KW - host specificity KW - rRNA 16S KW - D 04070:Pollution KW - SW 3040:Wastewater treatment processes KW - P 2000:FRESHWATER POLLUTION KW - A 01450:Environmental Pollution & Waste Treatment KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19996329?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Bifidobacteria+in+Feces+and+Environmental+Waters&rft.au=Lamendella%2C+Regina%3BDomingo%2C+Jorge+WSanto%3BKelty%2C+Catherine%3BOerther%2C+Daniel+B&rft.aulast=Lamendella&rft.aufirst=Regina&rft.date=2008-02-01&rft.volume=74&rft.issue=3&rft.spage=575&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Phylogeny; Host specificity; Surface water; Polymerase chain reaction; Watersheds; Feces; Wastewater treatment; rRNA 16S; Pollution; Anaerobic bacteria; Fecal coliforms; Water sampling; DNA; host specificity; Natural Waters; Water Analysis; Microorganisms; Indicators; Assay; Surface Water; Anaerobic Bacteria; Bifidobacterium adolescentis ER - TY - JOUR T1 - Quantifying fungal viability in air and water samples using quantitative PCR after treatment with propidium monoazide (PMA) AN - 19802639; 8091385 AB - A method is described to discriminate between live and dead cells of the infectious fungi Aspergillus fumigatus, Aspergillus flavus, Aspergillus terreus, Mucor racemosus, Rhizopus stolonifer and Paecilomyces variotii. To test the method, conidial suspensions were heat inactivated at 85 super(o)C or held at 5 super(o)C (controls) for 1 h. Polycarbonate filters (25 mm diameter, 0.8 mu m pore size) were placed on ''welled'' slides (14 mm diameter) and the filters treated with either PBS or PMA. Propidium monoazide (PMA), which enters dead cells but not live cells, was incubated with cell suspensions, exposed to blue wavelength light-emitting diodes (LED) to inactivate remaining PMA and secure intercalation of PMA with DNA of dead cells. Treated cells were extracted and the live and dead cells evaluated with quantitative PCR (QPCR). After heat treatment and DNA modification with PMA, all fungal species tested showed an approximate 100- to 1000-fold difference in cell viability estimated by QPCR analysis which was consistent with estimates of viability based on culturing. JF - Journal of Microbiological Methods AU - Vesper, S AU - McKinstry, C AU - Hartmann, C AU - Neace, M AU - Yoder, S AU - Vesper, A AD - United States (US) Environmental Protection Agency, 26 West M.L. King Ave., M.L. 314, Cincinnati, OH 45268, United States, vesper.stephen@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 180 EP - 184 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 72 IS - 2 SN - 0167-7012, 0167-7012 KW - Biochemistry Abstracts 2: Nucleic Acids; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Cell suspensions KW - Aspergillus flavus KW - Phorbol esters KW - Fungi KW - Mucor racemosus KW - Filters KW - Pores KW - Heat KW - Aspergillus fumigatus KW - Polymerase chain reaction KW - Paecilomyces variotii KW - Wavelength KW - Intercalation KW - Aspergillus terreus KW - Rhizopus stolonifer KW - Heat treatments KW - polycarbonate KW - A 01450:Environmental Pollution & Waste Treatment KW - K 03300:Methods KW - N 14810:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19802639?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=Quantifying+fungal+viability+in+air+and+water+samples+using+quantitative+PCR+after+treatment+with+propidium+monoazide+%28PMA%29&rft.au=Vesper%2C+S%3BMcKinstry%2C+C%3BHartmann%2C+C%3BNeace%2C+M%3BYoder%2C+S%3BVesper%2C+A&rft.aulast=Vesper&rft.aufirst=S&rft.date=2008-02-01&rft.volume=72&rft.issue=2&rft.spage=180&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2007.11.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Cell suspensions; Filters; Pores; Phorbol esters; Heat; Fungi; Polymerase chain reaction; Intercalation; Wavelength; Heat treatments; polycarbonate; Aspergillus flavus; Aspergillus fumigatus; Mucor racemosus; Paecilomyces variotii; Rhizopus stolonifer; Aspergillus terreus DO - http://dx.doi.org/10.1016/j.mimet.2007.11.017 ER - TY - JOUR T1 - Testing Antimicrobial Paint Efficacy on Gypsum Wallboard Contaminated with Stachybotrys chartarum AN - 19606691; 8502031 AB - The goal of this research was to reduce occupant exposure to indoor mold through the efficacy testing of antimicrobial paints. An accepted method for handling Stachybotrys chartarum-contaminated gypsum wallboard (GWB) is removal and replacement. This practice is also recommended for water-damaged or mold-contaminated GWB but is not always followed completely. The efficacy of antimicrobial paints to eliminate or control mold regrowth on surfaces can be tested easily on nonporous surfaces. The testing of antimicrobial efficacy on porous surfaces found in the indoor environment, such as gypsum wallboard, can be more complicated and prone to incorrect conclusions regarding residual organisms. The mold S. chartarum has been studied for toxin production and its occurrence in water-damaged buildings. Research to control its growth using seven different antimicrobial paints and two commonly used paints on contaminated, common gypsum wallboard was performed in laboratory testing at high relative humidity. The results indicate differences in antimicrobial efficacy for the period of testing, and that proper cleaning and resurfacing of GWB with an antimicrobial paint can be an option in those unique circumstances when removal may not be possible. JF - Journal of Occupational and Environmental Hygiene AU - Menetrez, M Y AU - Foarde, K K AU - Webber, T D AU - Dean, T R AU - Betancourt, D A AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Air Pollution Prevention and Control Division, Research Triangle Park, North Carolina Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 63 EP - 66 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 5 IS - 2 SN - 1545-9624, 1545-9624 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Health & Safety Science Abstracts KW - Relative humidity KW - regrowth KW - Laboratory testing KW - Humidity KW - Molds KW - Stachybotrys chartarum KW - Buildings KW - Toxins KW - Stachybotrys KW - gypsum KW - Indoor environments KW - antimicrobial agents KW - Paints KW - Environmental hygiene KW - A 01340:Antibiotics & Antimicrobials KW - H 14000:Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19606691?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Hygiene&rft.atitle=Testing+Antimicrobial+Paint+Efficacy+on+Gypsum+Wallboard+Contaminated+with+Stachybotrys+chartarum&rft.au=Menetrez%2C+M+Y%3BFoarde%2C+K+K%3BWebber%2C+T+D%3BDean%2C+T+R%3BBetancourt%2C+D+A&rft.aulast=Menetrez&rft.aufirst=M&rft.date=2008-02-01&rft.volume=5&rft.issue=2&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Hygiene&rft.issn=15459624&rft_id=info:doi/10.1080%2F15459620701778762 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Relative humidity; gypsum; Molds; Toxins; Environmental hygiene; Paints; regrowth; Laboratory testing; Humidity; Indoor environments; Buildings; antimicrobial agents; Stachybotrys; Stachybotrys chartarum DO - http://dx.doi.org/10.1080/15459620701778762 ER - TY - JOUR T1 - Dechlorination kinetics of monochlorobiphenyls by Fe/Pd: Effects of solvent, temperature, and PCB concentration AN - 19559323; 8751890 AB - Well-known, yet undefined, changes in the conditions and activity of palladized zerovalent iron (Fe/Pd) over an extended period of time hindered a careful study of dechlorination kinetics in long-term experiments. A short- term experimental method was, therefore, developed to study the effects of temperature and solvent on the dechlorination of monochlorobiphenyls (MCBs), 2-chlorobiphenyl (2-ClBP), in particular by Fe/Pd. The experiments started with specified initial conditions and lasted only for 10 min. The average value (k) of the first-order rate constant for the dechlorination of 2- ClBP was 0.13 +/- 0.03 L m super(-2) h super(-1), not significantly different from the average values for 3-chlorobiphenyl and 4-chlorobiphenyl. The apparent activation energy was 20 +/- 4 kJ mol super(-1) and 17 +/- 7 kJ mol super(-1), in a temperature range between 4 degree C and 60 degree C, for the dechlorination of 2-ClBP using two batches of Fe/Pd catalyst. The k values decreased significantly in mixtures with a methanol concentration higher than 10%. The values of the rate constant were slightly influenced by the initial concentrations in the experiments at a low temperature and in a solution with a high methanol concentration. The concentration dependence was described with a Langmuir equation, based on the Langmuir-Hinshelwood mechanism that includes an adsorption step of a single species preceding a rate-determining catalytic reaction. JF - Applied Catalysis B: Environmental AU - Fang, Yuanxiang AU - Al-Abed, Souhail R AD - U.S. Environmental Protection Agency, National Risk Management Research Laboratory, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA, al-abed.souhail@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 371 EP - 380 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 78 IS - 3-4 SN - 0926-3373, 0926-3373 KW - Pollution Abstracts KW - Dechlorination KW - Temperature KW - Solvents KW - Bioaccumulation KW - Kinetics KW - low temperature KW - Adsorption KW - Catalysts KW - Iron KW - Catalysis KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19559323?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Catalysis+B%3A+Environmental&rft.atitle=Dechlorination+kinetics+of+monochlorobiphenyls+by+Fe%2FPd%3A+Effects+of+solvent%2C+temperature%2C+and+PCB+concentration&rft.au=Fang%2C+Yuanxiang%3BAl-Abed%2C+Souhail+R&rft.aulast=Fang&rft.aufirst=Yuanxiang&rft.date=2008-02-01&rft.volume=78&rft.issue=3-4&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Applied+Catalysis+B%3A+Environmental&rft.issn=09263373&rft_id=info:doi/10.1016%2Fj.apcatb.2007.09.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Dechlorination; Bioaccumulation; Kinetics; Adsorption; low temperature; Solvents; Temperature; Catalysts; Iron; Catalysis DO - http://dx.doi.org/10.1016/j.apcatb.2007.09.009 ER - TY - JOUR T1 - Calibration of subsurface batch and reactive-transport models involving complex biogeochemical processes AN - 1287378608; 2013-018808 AB - In this study, the calibration of subsurface batch and reactive-transport models involving complex biogeochemical processes was systematically evaluated. Two hypothetical nitrate biodegradation scenarios were developed and simulated in numerical experiments to evaluate the performance of three calibration search procedures: a multi-start non-linear regression algorithm (i.e. multi-start Levenberg-Marquardt), a global search heuristic (i.e. particle swarm optimization), and a hybrid algorithm that combines the particle swarm procedure with a regression-based "polishing" step. Graphical analysis of the selected calibration problems revealed heterogeneous regions of extreme parameter sensitivity and insensitivity along with abundant numbers of local minima. These characteristics hindered the performance of the multi-start non-linear regression technique, which was generally the least effective of the considered algorithms. In most cases, the global search and hybrid methods were capable of producing improved model fits at comparable computational expense. In other cases, the multi-start and hybrid calibration algorithms yielded comparable fitness values but markedly differing parameter estimates and associated uncertainty measures. Abstract Copyright (2008) Elsevier, B.V. JF - Advances in Water Resources AU - Matott, L Shawn AU - Rabideau, Alan J Y1 - 2008/02// PY - 2008 DA - February 2008 SP - 269 EP - 286 PB - Elsevier, Oxford VL - 31 IS - 2 SN - 0309-1708, 0309-1708 KW - dispersivity KW - degradation KW - calibration KW - simulation KW - manganese KW - iron KW - transport KW - denitrification KW - reactive transport KW - reduction KW - algorithms KW - geochemistry KW - uncertainty KW - functions KW - concentration KW - biodegradation KW - numerical models KW - sulfates KW - pollutants KW - biochemistry KW - statistical analysis KW - pollution KW - optimization KW - nitrates KW - advection KW - aquifers KW - saturation KW - metals KW - regression analysis KW - particles KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1287378608?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Water+Resources&rft.atitle=Calibration+of+subsurface+batch+and+reactive-transport+models+involving+complex+biogeochemical+processes&rft.au=Matott%2C+L+Shawn%3BRabideau%2C+Alan+J&rft.aulast=Matott&rft.aufirst=L&rft.date=2008-02-01&rft.volume=31&rft.issue=2&rft.spage=269&rft.isbn=&rft.btitle=&rft.title=Advances+in+Water+Resources&rft.issn=03091708&rft_id=info:doi/10.1016%2Fj.advwatres.2007.08.005 L2 - http://www.sciencedirect.com/science/journal/03091708 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2013-01-01 N1 - Number of references - 106 N1 - Document feature - illus. incl. 12 tables N1 - Last updated - 2013-02-14 N1 - SubjectsTermNotLitGenreText - advection; algorithms; aquifers; biochemistry; biodegradation; calibration; concentration; degradation; denitrification; dispersivity; functions; geochemistry; iron; manganese; metals; nitrates; numerical models; optimization; particles; pollutants; pollution; reactive transport; reduction; regression analysis; saturation; simulation; statistical analysis; sulfates; transport; uncertainty DO - http://dx.doi.org/10.1016/j.advwatres.2007.08.005 ER - TY - JOUR T1 - Mechanism of asthmatic exacerbation by ambient air pollution particles AN - 1069194870; 16579975 AB - In the previous two to three decades, the prevalence of asthma has risen in numerous countries of the world. Correlating with this elevated prevalence of asthma, societies have observed increased air pollution from specific sources. Studies have implicated certain pollutants in asthmatic exacerbation. Particulate matter (PM) is the pollutant most frequently identified with worsening of this airway disease. PM is a temporally and spatially shifting suspension of solids and liquids originating from both natural and anthropogenic sources. Exposures to elevated levels of PM have been associated with asthmatic exacerbations by employing a diverse array of end points, including respiratory symptoms, use of medication, medical visits, emergency room visits, hospital admissions and pulmonary function decrements. Pertinent to worsening of asthma by ambient air PM, there are other particle-associated exposures that similarly precipitate asthmatic exacerbations. These include traffic-associated pollutants, diesel exhaust, emissions from gas and wood stoves, burning of biomass and environmental tobacco smoke. It is widely accepted that the biological effects exerted by all particle exposures result from oxidative stress. This stimulates cell signaling, transcription factor activation and mediator release in the respiratory tract, culminating in inflammation. Other postulated mechanisms for asthmatic exacerbation following PM exposure include an impact on the incidence of infections and adjuvant effects. JF - Expert Review of Respiratory Medicine AU - Ghio, Andrew J AD - Human Studies Division, NHEERL, USEPA, Research Triangle Park, NC 27711, USA., ghio.andy@epa.gov Y1 - 2008/02// PY - 2008 DA - Feb 2008 SP - 109 EP - 118 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 2 IS - 1 SN - 1747-6348, 1747-6348 KW - Pollution Abstracts KW - Air pollution KW - Asthma KW - Biomass KW - Infection KW - Particulates KW - Respiratory diseases KW - Respiratory function KW - Respiratory tract KW - Wood KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1069194870?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Respiratory+Medicine&rft.atitle=Mechanism+of+asthmatic+exacerbation+by+ambient+air+pollution+particles&rft.au=Ghio%2C+Andrew+J&rft.aulast=Ghio&rft.aufirst=Andrew&rft.date=2008-02-01&rft.volume=2&rft.issue=1&rft.spage=109&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Respiratory+Medicine&rft.issn=17476348&rft_id=info:doi/10.1586%2F17476348.2.1.109 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Number of references - 123 N1 - Last updated - 2012-12-03 N1 - SubjectsTermNotLitGenreText - Air pollution; Wood; Asthma; Respiratory function; Respiratory diseases; Particulates; Biomass; Infection; Respiratory tract DO - http://dx.doi.org/10.1586/17476348.2.1.109 ER - TY - JOUR T1 - Genotoxicity of 10 cigarette smoke condensates in four test systems: comparisons between assays and condensates. AN - 70219719; 18006367 AB - The particulate fraction of cigarette smoke, cigarette smoke condensate (CSC), is genotoxic in many short-term in vitro tests and is carcinogenic in rodents. However, no study has evaluated a series of CSCs prepared from a diverse set of cigarettes and produced with different smoking machine regimens in several short-term genotoxicity tests. Here we report on the genotoxicity of 10 CSCs prepared from commercial cigarettes that ranged from ultra-low tar per cigarette (14.5 mg) as determined by the Federal Trade Commission (FTC) smoking regimen, a reference cigarette blended to be representative of a U.S. FTC-regimen low-tar cigarette, and experimental cigarettes constructed of single tobacco types. CSCs were tested in the presence of rat liver S9 in the Salmonella plate-incorporation assay using frameshift strains TA98 and YG1041; in micronucleus and comet assays in L5178Y/Tk(+/-) 7.3.2C mouse lymphoma cells, and in CHO-K(1) cells for chromosome aberrations. All 10 CSCs were mutagenic in both strains of Salmonella, and the rank order of their mutagenic potencies was similar. Their mutagenic potencies in Salmonella spanned 7-fold when expressed as rev/mug CSC but 158-fold when expressed as rev/mg nicotine; the range of genotoxic potencies of the CSCs in the other assays was similar regardless of how the data were expressed. All 10 CSCs induced micronuclei with a 3-fold range in their potency. All but one CSC induced DNA damage over a 20-fold range, and all but one CSC induced chromosome aberrations over a 4-fold range. There was no relation among the genotoxic potencies of the CSCs across the assays, and a qualitative advantage of the addition of the other assays to the Salmonella assay was not supported by our findings. Although consideration of nicotine levels may improve the relevance of the quantitative data obtained in the Salmonella and possibly comet assays, compensatory smoking habits and other factors may make the data from the assays used here have qualitative but not quantitative value in assessing risk of cigarette types and cigarette smoking to human health. JF - Mutation research AU - DeMarini, David M AU - Gudi, Ramadevi AU - Szkudlinska, Anna AU - Rao, Meena AU - Recio, Leslie AU - Kehl, Margaret AU - Kirby, Paul E AU - Polzin, Gregory AU - Richter, Patricia A AD - Environmental Carcinogenesis Division, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Y1 - 2008/01/31/ PY - 2008 DA - 2008 Jan 31 SP - 15 EP - 29 VL - 650 IS - 1 SN - 0027-5107, 0027-5107 KW - Mutagens KW - 0 KW - Smoke KW - Index Medicus KW - Animals KW - Mutagenicity Tests KW - Cricetulus KW - CHO Cells KW - Mice KW - Cricetinae KW - Smoke -- adverse effects KW - Tobacco KW - Mutagens -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70219719?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mutation+research&rft.atitle=Genotoxicity+of+10+cigarette+smoke+condensates+in+four+test+systems%3A+comparisons+between+assays+and+condensates.&rft.au=DeMarini%2C+David+M%3BGudi%2C+Ramadevi%3BSzkudlinska%2C+Anna%3BRao%2C+Meena%3BRecio%2C+Leslie%3BKehl%2C+Margaret%3BKirby%2C+Paul+E%3BPolzin%2C+Gregory%3BRichter%2C+Patricia+A&rft.aulast=DeMarini&rft.aufirst=David&rft.date=2008-01-31&rft.volume=650&rft.issue=1&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Mutation+research&rft.issn=00275107&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-01 N1 - Date created - 2008-01-18 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: Mutat Res. 2008;652(2):208 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Sampling household surfaces for pesticide residues: comparison between a press sampler and solvent-moistened wipes. AN - 70104249; 17900665 AB - A modified Press Sampler was evaluated to determine the efficiency of pesticide transfer from household surfaces to collection disks as compared to wiping with a solvent-moistened gauze pad. Organophosphate (OP), pyrazole, and pyrethroid pesticides were applied to three hard flooring materials and carpet at two loading rates. Surfaces were dried and press sampled using C(18), 100% cotton or polyurethane foam (PUF) for either 2 or 10 min or wiped with isopropanol-moistened gauze pads. Transfer efficiencies (TE, %) were calculated as a fraction of surface loadings captured simultaneously on foil deposition coupons. The highest mean TEs (17-55%) for the Press Sampler were observed for OPs from hard surfaces to C(18), considering both contact times. Cotton and PUF transferred 6-27% and 5-30% of OPs, respectively. Corresponding mean TEs for pyrazole and pyrethroid pesticides were only 3% (C(18)), 2-3% (cotton) and 1-2% (PUF). Wipes of hard surfaces removed 84-97% of all pesticides while wipes of carpet removed 31-39%, much higher than transferred to any Press Sampler materials. The mean TEs suggested that the extent of pesticide residue transfer was affected by surface type, pesticide class, and sampling procedure. Wiping was more efficient than press sampling for pesticide surface residue measurements, particularly for loading rates typical of residences. JF - The Science of the total environment AU - Bernard, Craig E AU - Berry, Maurice R AU - Wymer, Larry J AU - Melnyk, Lisa Jo AD - US Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, 26 West Martin Luther King Drive, Cincinnati, Ohio 45268, USA. Y1 - 2008/01/25/ PY - 2008 DA - 2008 Jan 25 SP - 514 EP - 521 VL - 389 IS - 2-3 SN - 0048-9697, 0048-9697 KW - Environmental Pollutants KW - 0 KW - Pesticide Residues KW - Solvents KW - Index Medicus KW - Equipment Design KW - Surface Properties KW - Solvents -- chemistry KW - Housing -- standards KW - Pesticide Residues -- analysis KW - Environmental Pollutants -- analysis KW - Environmental Monitoring -- methods KW - Environmental Monitoring -- instrumentation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70104249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Sampling+household+surfaces+for+pesticide+residues%3A+comparison+between+a+press+sampler+and+solvent-moistened+wipes.&rft.au=Bernard%2C+Craig+E%3BBerry%2C+Maurice+R%3BWymer%2C+Larry+J%3BMelnyk%2C+Lisa+Jo&rft.aulast=Bernard&rft.aufirst=Craig&rft.date=2008-01-25&rft.volume=389&rft.issue=2-3&rft.spage=514&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=00489697&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-01 N1 - Date created - 2007-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Risks to aquatic organisms posed by human pharmaceutical use. AN - 70101786; 17936335 AB - In order to help prioritize future research efforts within the US, risks associated with exposure to human prescription pharmaceutical residues in wastewater were estimated from marketing and pharmacological data. Masses of 371 active pharmaceutical ingredients (APIs) dispensed in the US in 2004 were estimated from marketing data, and then divided by therapeutic dose rate to normalize for potency. Metabolic inactivation of the 50 most dispensed APIs was estimated from published data, and active metabolites were tabulated. Comparing maximum likely average wastewater concentrations of API-associated activity to exposure rates that produce therapeutic effects in humans suggests that the threat to healthy human adults from aquatic exposure is low, even when likely mixture effects are considered. Comparing predicted wastewater concentrations to human therapeutic plasma concentrations suggests that some APIs may be present at sufficient concentrations to affect organisms which eliminate them inefficiently. Comparing predicted antimicrobial concentrations to published minimum inhibitory concentrations suggests that antibacterial APIs in wastewater, but probably not antifungal APIs, may select for low-level antimicrobial resistance. The taxonomic distribution of molecular targets of the 50 most dispensed APIs suggests that potential effects of some APIs are likely restricted to vertebrates, while other APIs can probably affect many eukaryotic and prokaryotic clades. JF - The Science of the total environment AU - Kostich, Mitchell S AU - Lazorchak, James M AD - Ecological Exposure Research Division, U.S. Environmental Protection Agency, 26 W. Martin Luther King Drive, Cincinnati, OH 45268, USA. kostich.mitchell@epa.gov Y1 - 2008/01/25/ PY - 2008 DA - 2008 Jan 25 SP - 329 EP - 339 VL - 389 IS - 2-3 SN - 0048-9697, 0048-9697 KW - Pharmaceutical Preparations KW - 0 KW - Water Pollutants, Chemical KW - Index Medicus KW - Animals KW - Humans KW - Risk Assessment KW - Water Microbiology -- standards KW - Water Pollutants, Chemical -- analysis KW - Water Pollutants, Chemical -- toxicity KW - Environmental Exposure -- analysis KW - Pharmaceutical Preparations -- analysis KW - Models, Theoretical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70101786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Risks+to+aquatic+organisms+posed+by+human+pharmaceutical+use.&rft.au=Kostich%2C+Mitchell+S%3BLazorchak%2C+James+M&rft.aulast=Kostich&rft.aufirst=Mitchell&rft.date=2008-01-25&rft.volume=389&rft.issue=2-3&rft.spage=329&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=00489697&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-01 N1 - Date created - 2007-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - Information Tools to Help Anticipate and Adapt to the Effects of Climate Change on Water Quality T2 - 20th Conference on Climate Variability and Change (CVC 2008) AN - 40726418; 4769282 JF - 20th Conference on Climate Variability and Change (CVC 2008) AU - Scheraga, Joel Y1 - 2008/01/20/ PY - 2008 DA - 2008 Jan 20 KW - Climatic changes KW - Water quality KW - Environmental effects KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40726418?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=20th+Conference+on+Climate+Variability+and+Change+%28CVC+2008%29&rft.atitle=Information+Tools+to+Help+Anticipate+and+Adapt+to+the+Effects+of+Climate+Change+on+Water+Quality&rft.au=Scheraga%2C+Joel&rft.aulast=Scheraga&rft.aufirst=Joel&rft.date=2008-01-20&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=20th+Conference+on+Climate+Variability+and+Change+%28CVC+2008%29&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/88Annual/techprogram/programexpanded_438.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of Ambient Ozone and Precursor Monitoring Data in New Orleans and Baton Rouge, Louisiana before and after Hurricane Katrina T2 - 15th Joint Conference on the Applications of Air Pollution Meteorology with Air and Waste Management Association AN - 40721000; 4762075 JF - 15th Joint Conference on the Applications of Air Pollution Meteorology with Air and Waste Management Association AU - Sather, Mark E Y1 - 2008/01/20/ PY - 2008 DA - 2008 Jan 20 KW - USA, Louisiana KW - USA, Louisiana, Baton Rouge KW - USA, Louisiana, New Orleans KW - Ozone KW - Hurricanes KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40721000?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=15th+Joint+Conference+on+the+Applications+of+Air+Pollution+Meteorology+with+Air+and+Waste+Management+Association&rft.atitle=Analysis+of+Ambient+Ozone+and+Precursor+Monitoring+Data+in+New+Orleans+and+Baton+Rouge%2C+Louisiana+before+and+after+Hurricane+Katrina&rft.au=Sather%2C+Mark+E&rft.aulast=Sather&rft.aufirst=Mark&rft.date=2008-01-20&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=15th+Joint+Conference+on+the+Applications+of+Air+Pollution+Meteorology+with+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/88Annual/techprogram/programexpanded_441.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An Evaluation of the WRF-CMAQ Experimental Air Quality Forecast Model for the Summer of 2007 T2 - 15th Joint Conference on the Applications of Air Pollution Meteorology with Air and Waste Management Association AN - 40720999; 4762009 JF - 15th Joint Conference on the Applications of Air Pollution Meteorology with Air and Waste Management Association AU - Eder, Brian K AU - Mathur, R AU - Kang, D AU - Yu, S. Y1 - 2008/01/20/ PY - 2008 DA - 2008 Jan 20 KW - Air quality KW - Summer KW - Models KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40720999?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=15th+Joint+Conference+on+the+Applications+of+Air+Pollution+Meteorology+with+Air+and+Waste+Management+Association&rft.atitle=An+Evaluation+of+the+WRF-CMAQ+Experimental+Air+Quality+Forecast+Model+for+the+Summer+of+2007&rft.au=Eder%2C+Brian+K%3BMathur%2C+R%3BKang%2C+D%3BYu%2C+S.&rft.aulast=Eder&rft.aufirst=Brian&rft.date=2008-01-20&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=15th+Joint+Conference+on+the+Applications+of+Air+Pollution+Meteorology+with+Air+and+Waste+Management+Association&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/88Annual/techprogram/programexpanded_441.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Origins and temporal scales of hypoxia on the Louisiana shelf: Importance of benthic and sub-pycnocline water metabolism AN - 20874190; 8183914 AB - Hypoxic-to-anoxic conditions (2-0 mg O sub(2) l super(-) super(1)) occur in the bottom waters of the northern Gulf of Mexico on the Louisiana shelf west of the Mississippi river delta during late spring and summer where the rate of oxygen consumption exceeds its rate of input from physical transport plus photosynthetic generation. Although consumption of oxygen in the water column primarily via oxic respiration is an important process, the loss of oxygen at and near the seafloor may also be an important sink contributing to seasonal low oxygen conditions in the relatively shallow overlying waters in this region. Associated with the flux of oxygen into the sediments is the flux of nutrients out of the sediments from the remineralization of sedimentary organic matter via a number of possible electron acceptors. The nutrients that are released from the sediment can potentially stimulate further primary production. This can lead to generation of oxygen in the water column and production of organic matter, much of which can be transported to the seafloor where it again becomes a sink for oxygen. A non-steady-state data driven numeric benthic-pelagic model was developed to investigate the role of sediment and water-column metabolism in the development of hypoxia on the Louisiana shelf. The model simulations bare out the importance of sediment oxygen demand as the primary sink for oxygen at the beginning and end of a hypoxic event on the shelf, but once hypoxia has developed, the sediments, now isolated from the oxygen-rich surface waters, are driven into a more anoxic mode, becoming more dependent on sulfate and metal reduction. As a result, the bottom water near the pycnocline becomes the major sink for oxygen. Model simulations also suggest that there is a delay of several weeks between metabolite production (especially ammonium) and its efflux from the sediments. Thus the maximum sediment ammonium export occurs in September and October in time to fuel autumnal phytoplankton production, thereby continuing a biogeochemical cycle that expands the temporal and spatial scales of hypoxia on the Louisiana shelf. JF - Marine Chemistry AU - Eldridge, P M AU - Morse, J W AD - Pacific Coastal Ecology Branch, US Environmental Protection Agency, 2111 S. E. Marine Science Dr., Newport, OR 97365, United States, eldridge.pete@epa.gov Y1 - 2008/01/16/ PY - 2008 DA - 2008 Jan 16 SP - 159 EP - 171 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 108 IS - 3-4 SN - 0304-4203, 0304-4203 KW - Pollution Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 2: Ocean Technology Policy & Non-Living Resources; Oceanic Abstracts KW - Sulfates KW - ASW, USA, Louisiana KW - Bottom water KW - Photosynthesis KW - Heavy metals KW - Fuels KW - Phytoplankton KW - Nutrients KW - Primary production KW - Water column KW - Remineralization KW - ASW, USA, Mississippi R. Delta KW - Sedimentation KW - Ocean floor KW - Ammonium compounds KW - Rivers KW - Oxygen consumption KW - Ammonium KW - Sediment chemistry KW - nutrients KW - Oxygen KW - Sediment-water interface KW - Metabolism KW - Surface water KW - Respiration KW - Metabolites KW - pycnoclines KW - Models KW - Sediment transport KW - Marine KW - Data processing KW - Organic matter KW - Simulation KW - Sediments KW - Sulfate KW - ASW, Mexico Gulf KW - Hypoxia KW - water column KW - O 1070:Ecology/Community Studies KW - Q2 09264:Sediments and sedimentation KW - P 1000:MARINE POLLUTION KW - K 03450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20874190?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Chemistry&rft.atitle=Origins+and+temporal+scales+of+hypoxia+on+the+Louisiana+shelf%3A+Importance+of+benthic+and+sub-pycnocline+water+metabolism&rft.au=Eldridge%2C+P+M%3BMorse%2C+J+W&rft.aulast=Eldridge&rft.aufirst=P&rft.date=2008-01-16&rft.volume=108&rft.issue=3-4&rft.spage=159&rft.isbn=&rft.btitle=&rft.title=Marine+Chemistry&rft.issn=03044203&rft_id=info:doi/10.1016%2Fj.marchem.2007.11.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Oxygen consumption; Sediment chemistry; Bottom water; Sediment-water interface; Hypoxia; Sediment transport; Ocean floor; Sedimentation; Ammonium compounds; Rivers; Ammonium; Data processing; Heavy metals; Surface water; Respiration; Fuels; Organic matter; Phytoplankton; pycnoclines; Nutrients; Metabolites; Primary production; Sediments; Water column; Sulfate; Models; Remineralization; Metabolism; Sulfates; Photosynthesis; Simulation; nutrients; Oxygen; water column; ASW, Mexico Gulf; ASW, USA, Louisiana; ASW, USA, Mississippi R. Delta; Marine DO - http://dx.doi.org/10.1016/j.marchem.2007.11.009 ER - TY - JOUR T1 - A reproducible method for determination of nitrocellulose in soil. AN - 70446327; 18371744 AB - A reproducible analytical method for determination of nitrocellulose in soil is described. The new method provides the precision and accuracy needed for quantitation of nitrocellulose in soils to enable worker safety on contaminated sites. The method utilizes water and ethanol washes to remove co-contaminants, acetone extraction of nitrocellulose, and base hydrolysis of the extract to reduce nitrate groups. The hydrolysate is then neutralized and analyzed by ion chromatography for determination of free nitrate and nitrite. A variety of bases for hydrolysis and acids for neutralization were evaluated, with 5N sodium hydroxide and carbon dioxide giving the most complete hydrolysis and interference-free neutralization, respectively. The concentration of nitrocellulose in the soil is calculated from the concentrations of nitrate and nitrite and the weight percentage of nitrogen content in nitrocellulose. The laboratory detection limit for the analysis is 10mg/kg. The method acceptance range for recovery of nitrocellulose from control samples is 78-105%. JF - Talanta AU - Macmillan, Denise K AU - Majerus, Chelsea R AU - Laubscher, Randy D AU - Shannon, John P AD - Engineer Research and Development Center, Environmental Laboratory, 3909 Halls Ferry Road, Vicksburg, MS 39180, USA. macmillan.denise@epa.gov Y1 - 2008/01/15/ PY - 2008 DA - 2008 Jan 15 SP - 1026 EP - 1031 VL - 74 IS - 4 KW - Soil Pollutants KW - 0 KW - Collodion KW - 9004-70-0 KW - Index Medicus KW - Reproducibility of Results KW - Hydrolysis KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70446327?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Talanta&rft.atitle=A+reproducible+method+for+determination+of+nitrocellulose+in+soil.&rft.au=Macmillan%2C+Denise+K%3BMajerus%2C+Chelsea+R%3BLaubscher%2C+Randy+D%3BShannon%2C+John+P&rft.aulast=Macmillan&rft.aufirst=Denise&rft.date=2008-01-15&rft.volume=74&rft.issue=4&rft.spage=1026&rft.isbn=&rft.btitle=&rft.title=Talanta&rft.issn=1873-3573&rft_id=info:doi/10.1016%2Fj.talanta.2007.08.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-08-26 N1 - Date created - 2008-03-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.talanta.2007.08.013 ER - TY - JOUR T1 - 1997-2007; the first example of a long-term geochemical monitoring; results and perspectives from the Umbria region seismic area AN - 919636095; 2012-016844 JF - Geophysical Research Abstracts AU - Bonfanti, P AU - Bovini, S AU - Italiano, F AU - Lemmi, M AU - Martinelli, G AU - Anonymous Y1 - 2008 PY - 2008 DA - 2008 SP - EGU2008 EP - A-10038 PB - Copernicus GmbH on behalf of the European Geosciences Union (EGU), Katlenburg-Lindau VL - 10 SN - 1029-7006, 1029-7006 KW - history KW - monitoring KW - seismicity KW - earthquake prediction KW - geochemical methods KW - Umbria-Marche earthquakes 1997 KW - geochemistry KW - earthquakes KW - carbon dioxide KW - 19:Seismology KW - 02C:Geochemistry of rocks, soils, and sediments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/919636095?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geophysical+Research+Abstracts&rft.atitle=1997-2007%3B+the+first+example+of+a+long-term+geochemical+monitoring%3B+results+and+perspectives+from+the+Umbria+region+seismic+area&rft.au=Bonfanti%2C+P%3BBovini%2C+S%3BItaliano%2C+F%3BLemmi%2C+M%3BMartinelli%2C+G%3BAnonymous&rft.aulast=Bonfanti&rft.aufirst=P&rft.date=2008-01-01&rft.volume=10&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Geophysical+Research+Abstracts&rft.issn=10297006&rft_id=info:doi/ L2 - http://www.copernicus.org/EGU/gra/gra.html LA - English DB - GeoRef N1 - Conference title - European Geosciences Union general assembly 2008 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - carbon dioxide; earthquake prediction; earthquakes; geochemical methods; geochemistry; history; monitoring; seismicity; Umbria-Marche earthquakes 1997 ER - TY - JOUR T1 - A vulnerability evaluation framework for geological storage of carbon dioxide AN - 911676117; 2012-004035 AB - Carbon dioxide capture and storage has been identified as one of several approaches with the potential to address climate change. Storage technologies include geologic sequestration, ocean storage, and mineral carbonation. Of these, geological storage (GS), the process of injecting captured carbon dioxide into deep subsurface rock formations for long-term storage, has been identified as the most technically feasible approach. While a large body of literature indicates that GS is a viable technology that can be conducted in a safe manner, it is important that this technology be developed in concert with a comprehensive and systematic approach to ensure the protection of human health and the environment. With that in mind, the U.S. Environmental Protection Agency developed a Vulnerability Evaluation Framework (VEF) to systematically identify those geologic characteristics and other conditions that could increase the potential for adverse impacts from GS projects. The VEF was developed to provide policymakers, stakeholders, industry, and the public with a transparent framework to evaluate vulnerabilities of GS systems. It is based on a review of available GS literature, applicable technical knowledge, and consultation with experts. The VEF has a number of potential applications, including providing permitting assistance (guidance) to regulators, informing site-specific risk assessments and risk management decisions, identifying potential vulnerabilities that could affect siting decisions and possibly constrain carbon dioxide reservoir capacities, and informing and prioritizing approaches to measurement, monitoring, and verification. The VEF is focused on the three main parts of GS systems: the injection zone, the confining system, and the carbon dioxide stream. It takes a step-wise approach to evaluating these system attributes and then identifies potential impact categories that should be considered. The VEF first identifies and provides approaches to evaluate key geologic attributes of GS systems that could influence (i.e., increase or decrease) the vulnerability to leakage or pressure changes. It then provides an approach to define the area that should be evaluated for adverse impacts associated with leakage or pressure changes. Finally, the VEF identifies receptors that could be adversely impacted if leakage or pressure changes were to occur. These include receptors within the broad impact categories of human health and welfare, the atmosphere, ecological receptors (e.g., terrestrial and aquatic organisms), surface water and groundwater, and the physical environment. The assessment of vulnerabilities to leakage, pressure changes, and the potential impacts to receptors are described in a series of detailed decision-support flowcharts. JF - International Geological Congress, Abstracts = Congres Geologique International, Resumes AU - Karimjee, Anhar AU - Ritter, Kaylene AU - Anonymous Y1 - 2008 PY - 2008 DA - 2008 EP - Abstract 1353149 PB - [International Geological Congress], [location varies] VL - 33 KW - safety KW - carbon sequestration KW - underground storage KW - underground installations KW - pollution KW - risk assessment KW - greenhouse gases KW - evaluation KW - carbon dioxide KW - air pollution KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911676117?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Geological+Congress%2C+Abstracts+%3D+Congres+Geologique+International%2C+Resumes&rft.atitle=A+vulnerability+evaluation+framework+for+geological+storage+of+carbon+dioxide&rft.au=Karimjee%2C+Anhar%3BRitter%2C+Kaylene%3BAnonymous&rft.aulast=Karimjee&rft.aufirst=Anhar&rft.date=2008-01-01&rft.volume=33&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Geological+Congress%2C+Abstracts+%3D+Congres+Geologique+International%2C+Resumes&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - 33rd international geological congress N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by International Geological Congress Organizational Committee N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-06-07 N1 - CODEN - IGABBY N1 - SubjectsTermNotLitGenreText - air pollution; carbon dioxide; carbon sequestration; evaluation; greenhouse gases; pollution; risk assessment; safety; underground installations; underground storage ER - TY - JOUR T1 - Mechanochemical origin of carbon dioxide from sedimentary rocks AN - 864946423; 2011-037315 JF - Geophysical Research Abstracts AU - Pizzullo, S AU - Italiano, F AU - Martinelli, G AU - Plescia, P AU - Anonymous Y1 - 2008 PY - 2008 DA - 2008 SP - EGU2008 EP - A-10454 PB - Copernicus GmbH on behalf of the European Geosciences Union (EGU), Katlenburg-Lindau VL - 10 SN - 1029-7006, 1029-7006 KW - experimental studies KW - lattice KW - aragonite KW - shear stress KW - mechanism KW - gases KW - carbon dioxide KW - genesis KW - laboratory studies KW - sedimentary rocks KW - polymorphism KW - calcium carbonate KW - tectonics KW - greenhouse gases KW - geochemistry KW - carbonates KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864946423?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geophysical+Research+Abstracts&rft.atitle=Mechanochemical+origin+of+carbon+dioxide+from+sedimentary+rocks&rft.au=Pizzullo%2C+S%3BItaliano%2C+F%3BMartinelli%2C+G%3BPlescia%2C+P%3BAnonymous&rft.aulast=Pizzullo&rft.aufirst=S&rft.date=2008-01-01&rft.volume=10&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Geophysical+Research+Abstracts&rft.issn=10297006&rft_id=info:doi/ L2 - http://www.copernicus.org/EGU/gra/gra.html LA - English DB - GeoRef N1 - Conference title - European Geosciences Union general assembly 2008 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - aragonite; calcium carbonate; carbon dioxide; carbonates; experimental studies; gases; genesis; geochemistry; greenhouse gases; laboratory studies; lattice; mechanism; polymorphism; sedimentary rocks; shear stress; tectonics ER - TY - JOUR T1 - Chattanooga Creek site NAPL and creosote remediation utilizing AquaBlok (super R) low permeability thin capping approach AN - 755153851; 2010-078308 JF - AIPG Annual Meeting - Program AU - Collins, John A AU - Hull, John AU - Zeller, Craig AU - Valkenburg, John AU - Murphy, Barbara H AU - Font, Robert Y1 - 2008 PY - 2008 DA - 2008 SP - 38 PB - American Institute of Professional Geologists, [varies] VL - 45 KW - United States KW - water quality KW - creosote KW - reclamation KW - AquaBlock KW - Tennessee River KW - non-aqueous phase liquids KW - Chattanooga Creek KW - Tennessee KW - Chattanooga Tennessee KW - waste disposal KW - coal tar KW - permeability KW - disposal barriers KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/755153851?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIPG+Annual+Meeting+-+Program&rft.atitle=Chattanooga+Creek+site+NAPL+and+creosote+remediation+utilizing+AquaBlok+%28super+R%29+low+permeability+thin+capping+approach&rft.au=Collins%2C+John+A%3BHull%2C+John%3BZeller%2C+Craig%3BValkenburg%2C+John%3BMurphy%2C+Barbara+H%3BFont%2C+Robert&rft.aulast=Collins&rft.aufirst=John&rft.date=2008-01-01&rft.volume=45&rft.issue=&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=AIPG+Annual+Meeting+-+Program&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - American Institute of Professional Geologists 45th annual meeting, Arizona Hydrological Society 21st annual symposium, 3rd International Professional Geology conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Last updated - 2012-06-07 N1 - CODEN - #07078 N1 - SubjectsTermNotLitGenreText - AquaBlock; Chattanooga Creek; Chattanooga Tennessee; coal tar; creosote; disposal barriers; non-aqueous phase liquids; permeability; reclamation; Tennessee; Tennessee River; United States; waste disposal; water quality ER - TY - JOUR T1 - A pilot study of activity-based real-time airborne particle sampling for eronite and particle size at six villages in Cappadocia, Turkey AN - 742917618; 2010-054860 AB - From 4 to 16 April 2008, researchers from the University of Hawaii, University of Iowa, Ankara University, Hacettepe University, the U.S. Environmental Protection Agency (EPA), the U.S. Geological Survey (USGS), and Purdue University, conducted an environmental assessment of erionite, a human and animal carcinogen, in Cappadocia, Turkey. As part of this study personal (10 liters per minute, lpm), high volume (16 cubic feet per minute, cfm) and activity-based real-time (1 cfm) air sampling for air particulates was conducted at 6 villages in Cappadocia. The six villages included: Sarihidir, Karain, Tuzkoy, Nar, Boyali, and Karlik. Sites where sampling was conducted included: Mosques, homes, schools, and community centers. Preliminary analyses of the real-time data show that there was an increase in particulate concentration from the least amount of airborne particulate in the mosques to the most in the community centers. In addition, the particle size distribution profiles, ranging from 0.1 to 5.0 mu m could be characterized based on the sampling site and simulated work activities. Prior research suggests that the physiochemical and micro-morphologic characteristics of erionite, including particle size, may be a factor in the development of mesothelioma, a rare form of lung cancer world-wide, yet common in this region of Turkey. The findings from this pilot study may provide guidance in controlling exposures to erionite and prevent adverse health outcomes to those who live and work in this region of Turkey. JF - International Geological Congress, Abstracts = Congres Geologique International, Resumes AU - McGlothlin, James AU - Albrecht, William AU - Dogan, A Umran AU - Dogan, Meral AU - Miller, Aubrey AU - Brass, Brian AU - Nutt, Connie AU - Akkus, Murat AU - Michael, Carbone AU - Anonymous Y1 - 2008 PY - 2008 DA - 2008 EP - Abstract 1397041 PB - [International Geological Congress], [location varies] VL - 33 KW - silicates KW - geologic hazards KW - Tuzkoy Turkey KW - Cappadocia KW - environmental analysis KW - air pollution KW - carcinogens KW - size distribution KW - sampling KW - zeolite group KW - Boyali Turkey KW - framework silicates KW - Karlik Turkey KW - Asia KW - Middle East KW - Nar Turkey KW - erionite KW - pollutants KW - Sarihidir Turkey KW - grain size KW - Turkey KW - pollution KW - Karain Turkey KW - particles KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742917618?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Geological+Congress%2C+Abstracts+%3D+Congres+Geologique+International%2C+Resumes&rft.atitle=A+pilot+study+of+activity-based+real-time+airborne+particle+sampling+for+eronite+and+particle+size+at+six+villages+in+Cappadocia%2C+Turkey&rft.au=McGlothlin%2C+James%3BAlbrecht%2C+William%3BDogan%2C+A+Umran%3BDogan%2C+Meral%3BMiller%2C+Aubrey%3BBrass%2C+Brian%3BNutt%2C+Connie%3BAkkus%2C+Murat%3BMichael%2C+Carbone%3BAnonymous&rft.aulast=McGlothlin&rft.aufirst=James&rft.date=2008-01-01&rft.volume=33&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Geological+Congress%2C+Abstracts+%3D+Congres+Geologique+International%2C+Resumes&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - 33rd international geological congress N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by International Geological Congress Organizational Committee N1 - Date revised - 2010-01-01 N1 - Last updated - 2012-06-07 N1 - CODEN - IGABBY N1 - SubjectsTermNotLitGenreText - air pollution; Asia; Boyali Turkey; Cappadocia; carcinogens; environmental analysis; erionite; framework silicates; geologic hazards; grain size; Karain Turkey; Karlik Turkey; Middle East; Nar Turkey; particles; pollutants; pollution; sampling; Sarihidir Turkey; silicates; size distribution; Turkey; Tuzkoy Turkey; zeolite group ER - TY - JOUR T1 - Geomechanical issues related to the safe disposal of the radioactive waste at the Waste Isolation Pilot Plant AN - 742909262; 2010-052029 AB - INTRODUCTION The Waste Isolation Pilot Plant (WIPP) is a deep mined geologic repository located at a depth of 655 meters in the lower half of 600 meters thick, bedded salt deposit known as the Salado Formation. The WIPP facility is designed to store and isolate radioactive waste for 10,000-year regulatory period. This paper discusses the geomechanical issues which can potentially influence the performance and integrity of the WIPP. BACKGROUND The WIPP disposal system is composed of natural and engineered barriers. The primary natural barrier (the Salado) contains mainly halite with intercalation of laterally persistent thin layers of anhydrite, clay and polyhalite. The WIPP repository is composed of eight panels, each subdivided into seven identical rooms. Horizontal access drifts connect the disposal area with four vertical shafts. The average extraction ratio for the waste disposal area is expected to be less than 30. GEOMECHANICAL REVIEW OF THE WIPP REPOSITORY: The pre-mining stress field at the WIPP site is considered to be lithostatic (14.8MP) and isotropic. Mining disturbs the stress equilibrium and creates a gradient in the stress field. Halite of the Salado Formation behaves as a plastic material and exhibits time dependent deformation known as creep. Creep in the salt is driven by deviatoric stress. At a higher strain rates, which is associated with redistribution of stress can initiate brittle behavior in the salt and generate fractures and cracks approximately 3 to 4m deep and all around the cavity openings and this zone is known as Disturbed Rock Zone. GEOMECHANICAL ISSUES: Geomechanical issues represent changes in the mechanical field. Based on the origin, mechanics and developmental phase of the repository these issues can be divided into two main groups. These are grouped as "stability based", in which structural stability during operation is the primary concern, and "release based", which take place after the repository is closed and sealed. Released based issues include human intrusions as the main mechanism for release of radioactive materials to the accessible environment. Impact of these issues in two different phases are described below. Pre-decommissioning period : Creep in response to mining is considered to be the primary driving force for rock deformation and instability in this period. Geomechanical changes are primarily related to fracturing and displacement, shallow spall, clay slippage, roof fall and sag, floor heave, pillar movement and surface subsidence. Structural stability and life of the underground workings are affected by these changes. Post-decommissioning period: Release of radioactive materials by human intrusion includes mining, drilling, cuttings, caving, spalling, fluid injection and solution mining. Each of these activities has geomechanical significance in relation to fracturing, displacement, shear strength, mechanical inhomogeneity and movement towards the accessible environment. JF - International Geological Congress, Abstracts = Congres Geologique International, Resumes AU - Ghose, Shankar AU - Anonymous Y1 - 2008 PY - 2008 DA - 2008 EP - Abstract 1257885 PB - [International Geological Congress], [location varies] VL - 33 KW - United States KW - halides KW - shear strength KW - geologic hazards KW - Eddy County New Mexico KW - stability KW - New Mexico KW - land subsidence KW - displacements KW - radioactive waste KW - fractures KW - sedimentary rocks KW - chlorides KW - thickness KW - Waste Isolation Pilot Plant KW - heterogeneity KW - disposal barriers KW - Salado Formation KW - chemically precipitated rocks KW - Paleozoic KW - human activity KW - stress KW - deformation KW - Permian KW - evaporites KW - halite KW - Upper Permian KW - safety KW - creep KW - waste disposal KW - salt KW - pillars KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742909262?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Geological+Congress%2C+Abstracts+%3D+Congres+Geologique+International%2C+Resumes&rft.atitle=Geomechanical+issues+related+to+the+safe+disposal+of+the+radioactive+waste+at+the+Waste+Isolation+Pilot+Plant&rft.au=Ghose%2C+Shankar%3BAnonymous&rft.aulast=Ghose&rft.aufirst=Shankar&rft.date=2008-01-01&rft.volume=33&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Geological+Congress%2C+Abstracts+%3D+Congres+Geologique+International%2C+Resumes&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - 33rd international geological congress N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by International Geological Congress Organizational Committee N1 - Date revised - 2010-01-01 N1 - Last updated - 2012-06-07 N1 - CODEN - IGABBY N1 - SubjectsTermNotLitGenreText - chemically precipitated rocks; chlorides; creep; deformation; displacements; disposal barriers; Eddy County New Mexico; evaporites; fractures; geologic hazards; halides; halite; heterogeneity; human activity; land subsidence; New Mexico; Paleozoic; Permian; pillars; radioactive waste; safety; Salado Formation; salt; sedimentary rocks; shear strength; stability; stress; thickness; United States; Upper Permian; waste disposal; Waste Isolation Pilot Plant ER - TY - JOUR T1 - Fine-scale simulations of aeolian sediment dispersion in a small area in the northern Chihuahuan Desert AN - 742908966; 2010-042767 JF - Journal of Geophysical Research AU - Bowker, George E AU - Gillette, Dale A AU - Bergametti, Gilles AU - Marticorena, Beatrice AU - Heist, David K Y1 - 2008 PY - 2008 DA - 2008 EP - Citation F02S11 PB - American Geophysical Union, Washington, DC VL - 113 IS - F2 SN - 0148-0227, 0148-0227 KW - eolian features KW - sand KW - orientation KW - North America KW - dunes KW - dispersivity KW - sediment transport KW - erosion KW - clastic sediments KW - fines KW - vegetation KW - simulation KW - deserts KW - northern Chihuahuan Desert KW - Chihuahuan Desert KW - transport KW - quantitative analysis KW - deposition KW - sediments KW - velocity KW - wind transport KW - 23:Geomorphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742908966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research&rft.atitle=Fine-scale+simulations+of+aeolian+sediment+dispersion+in+a+small+area+in+the+northern+Chihuahuan+Desert&rft.au=Bowker%2C+George+E%3BGillette%2C+Dale+A%3BBergametti%2C+Gilles%3BMarticorena%2C+Beatrice%3BHeist%2C+David+K&rft.aulast=Bowker&rft.aufirst=George&rft.date=2008-01-01&rft.volume=113&rft.issue=F2&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research&rft.issn=01480227&rft_id=info:doi/10.1029%2F2007JF000748 L2 - http://www.agu.org/journals/jgr/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2010-01-01 N1 - Number of references - 27 N1 - PubXState - DC N1 - Document feature - illus. incl. 2 tables N1 - SuppNotes - Part of a special section on Aeolian processes; field observations and modeling, edited by Lancaster, N. N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Chihuahuan Desert; clastic sediments; deposition; deserts; dispersivity; dunes; eolian features; erosion; fines; North America; northern Chihuahuan Desert; orientation; quantitative analysis; sand; sediment transport; sediments; simulation; transport; vegetation; velocity; wind transport DO - http://dx.doi.org/10.1029/2007JF000748 ER - TY - JOUR T1 - Capillary electrophoresis with laser-induced fluorescence: environmental applications. AN - 70488447; 18392568 AB - Capillary electrophoresis (CE), especially free-zone CE, offers a relatively simple separation with moderate selectivity based on the mobility of ions in solution. Laser-induced fluorescence (LIF) detection, an extremely sensitive technique, can be coupled with a variety of separation conditions to achieve sensitive and quantitative results. When these techniques are combined, CE/LIF provides the sensitivity and increased selectivity that makes trace level environmental analysis of fluorescent compounds possible at or below levels typical for gas chromatography (GC)/mass spectrometry (MS). We offer a panoramic review of the role of these tools in solving environmental and related analytical problems before providing a detailed experimental protocol. JF - Methods in molecular biology (Clifton, N.J.) AU - Riddick, Lee AU - Brumley, William C AD - National Exposure Research Laboratory, Environmental Sciences Division, US Environmental Protection Agency, Office of Research and Development, Las Vegas, NV, USA. Y1 - 2008 PY - 2008 DA - 2008 SP - 119 EP - 134 VL - 384 SN - 1064-3745, 1064-3745 KW - Fluoresceins KW - 0 KW - Index Medicus KW - Fluorescence KW - Specimen Handling KW - Solid Phase Extraction KW - Environment KW - Lasers KW - Electrophoresis, Capillary -- methods KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70488447?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Methods+in+molecular+biology+%28Clifton%2C+N.J.%29&rft.atitle=Capillary+electrophoresis+with+laser-induced+fluorescence%3A+environmental+applications.&rft.au=Riddick%2C+Lee%3BBrumley%2C+William+C&rft.aulast=Riddick&rft.aufirst=Lee&rft.date=2008-01-01&rft.volume=384&rft.issue=&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=Methods+in+molecular+biology+%28Clifton%2C+N.J.%29&rft.issn=10643745&rft_id=info:doi/10.1007%2F978-1-59745-376-9_6 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-07 N1 - Date created - 2008-04-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/978-1-59745-376-9_6 ER - TY - JOUR T1 - Analysis of the enantiomers of chiral pesticides and other pollutants in environmental samples by capillary electrophoresis. AN - 70483885; 18392570 AB - The generic method described here involves typical capillary electrophoresis (CE) techniques, with the addition of cyclodextrin chiral selectors to the electrolyte for enantiomer separation and also, in the case of neutral analytes, the further addition of a micelle-forming compound such as sodium dodecyl sulfate (SDS) for separation by the micellar electrokinetic chromatography (MEKC) mode of CE. This generic method has broad application for the separation and analysis of enantiomers of chiral pesticides and other small molecules in a variety of environmental matrices. Aqueous samples such as surface water are analyzed after simple filtration, but centrifugation is sometimes necessary for soil-water slurry samples. Soils and sediment must be extracted with a polar organic solvent such as methanol, which needs only to be evaporated to near dryness, diluted with water, and filtered before CE analysis. Simple borate or phosphate-based buffers are usually used in the CE electrolyte. The method must be optimized for the electrolyte composition, including the correct chiral selector and its concentration, as well as for column conditions and instrumental variables such as voltage. Specific methodologies for application of this generic CE method to follow the enantioselective microbial transformation of ruelene, a neutral organophosphorus insecticide, dichlorprop, an ionic phenoxyalkanoic acid herbicide, and bromochloroacetic acid, a drinking water disinfection byproduct, are provided. JF - Methods in molecular biology (Clifton, N.J.) AU - Garrison, Arthur W AU - Schmitt-Kopplin, Philippe AU - Avants, Jimmy K AD - US Environmental Protection Agency, National Exposure Research Laboratory, Athens, GA, USA. Y1 - 2008 PY - 2008 DA - 2008 SP - 157 EP - 170 VL - 384 SN - 1064-3745, 1064-3745 KW - Acetates KW - 0 KW - Environmental Pollutants KW - Organophosphorus Compounds KW - Pesticides KW - 2,4-Dichlorophenoxyacetic Acid KW - 2577AQ9262 KW - bromochloroacetic acid KW - 5589-96-8 KW - dichlorprop KW - J7YV2RKO6Q KW - crufomate KW - V82Q65924L KW - Index Medicus KW - Organophosphorus Compounds -- analysis KW - Acetates -- analysis KW - 2,4-Dichlorophenoxyacetic Acid -- analysis KW - Stereoisomerism KW - Reproducibility of Results KW - Acetates -- chemistry KW - Organophosphorus Compounds -- chemistry KW - Rivers -- chemistry KW - Quality Control KW - 2,4-Dichlorophenoxyacetic Acid -- analogs & derivatives KW - Pesticides -- chemistry KW - Pesticides -- analysis KW - Environmental Pollutants -- chemistry KW - Environmental Pollutants -- analysis KW - Electrophoresis, Capillary -- standards KW - Electrophoresis, Capillary -- methods KW - Electrophoresis, Capillary -- instrumentation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70483885?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Methods+in+molecular+biology+%28Clifton%2C+N.J.%29&rft.atitle=Analysis+of+the+enantiomers+of+chiral+pesticides+and+other+pollutants+in+environmental+samples+by+capillary+electrophoresis.&rft.au=Garrison%2C+Arthur+W%3BSchmitt-Kopplin%2C+Philippe%3BAvants%2C+Jimmy+K&rft.aulast=Garrison&rft.aufirst=Arthur&rft.date=2008-01-01&rft.volume=384&rft.issue=&rft.spage=157&rft.isbn=&rft.btitle=&rft.title=Methods+in+molecular+biology+%28Clifton%2C+N.J.%29&rft.issn=10643745&rft_id=info:doi/10.1007%2F978-1-59745-376-9_8 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-07 N1 - Date created - 2008-04-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/978-1-59745-376-9_8 ER - TY - JOUR T1 - Long-term land application of biosolids-a case study. AN - 70343030; 18309211 AB - Impact of long-term land application of biosolids on groundwater and soil quality of an application site, which had been operated for 8-15 years, was evaluated in this study. During and after the biosolids application, biosolids-amended soil, groundwater, and background soil samples were collected mainly for pathogen, nitrogen, phosphorus, and heavy metal analyses. Soil test data showed that there was no heavy metal accumulation in the biosolids-amended soil even after 10 years of biosolids application. Similar results were also observed from the groundwater samples in which the heavy metal concentrations in all groundwater samples were well below the maximum contamination levels of the drinking water standards. In addition, bacteriological levels of the soil and groundwater samples were close to the background level and below the permissible limits, respectively, thereby showing no pathogen contamination. However, nitrate-nitrogen contamination of the groundwater was occasionally observed probably due to an excess loading of the biosolids in the past. This problem can be alleviated by applying biosolids at agronomic rates so that no excess nitrogen is available for leaching down to the groundwater. JF - Water science and technology : a journal of the International Association on Water Pollution Research AU - Surampalli, R Y AU - Lai, K C K AU - Banerji, S K AU - Smith, J AU - Tyagi, R D AU - Lohani, B N AD - US EPA, PO Box 17-2141, Kansas City, Kansas 66117, USA. surampalli.rao@epamail.epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 345 EP - 352 VL - 57 IS - 3 SN - 0273-1223, 0273-1223 KW - Environmental Pollutants KW - 0 KW - Sewage KW - Soil KW - Water KW - 059QF0KO0R KW - Index Medicus KW - Environmental Pollutants -- pharmacology KW - Environmental Pollutants -- chemistry KW - Time Factors KW - Water -- analysis KW - Agriculture KW - Sewage -- adverse effects KW - Water -- chemistry KW - Soil -- analysis KW - Sewage -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70343030?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+science+and+technology+%3A+a+journal+of+the+International+Association+on+Water+Pollution+Research&rft.atitle=Long-term+land+application+of+biosolids-a+case+study.&rft.au=Surampalli%2C+R+Y%3BLai%2C+K+C+K%3BBanerji%2C+S+K%3BSmith%2C+J%3BTyagi%2C+R+D%3BLohani%2C+B+N&rft.aulast=Surampalli&rft.aufirst=R&rft.date=2008-01-01&rft.volume=57&rft.issue=3&rft.spage=345&rft.isbn=&rft.btitle=&rft.title=Water+science+and+technology+%3A+a+journal+of+the+International+Association+on+Water+Pollution+Research&rft.issn=02731223&rft_id=info:doi/10.2166%2Fwst.2008.024 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-24 N1 - Date created - 2008-02-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.2166/wst.2008.024 ER - TY - JOUR T1 - The role of particulate matter-associated zinc in cardiac injury in rats. AN - 70206218; 18197293 AB - Exposure to particulate matter (PM) has been associated with increased cardiovascular morbidity; however, causative components are unknown. Zinc is a major element detected at high levels in urban air. We investigated the role of PM-associated zinc in cardiac injury. We repeatedly exposed 12- to 14-week-old male Wistar Kyoto rats intratracheally (1x/week for 8 or 16 weeks) to a) saline (control); b) PM having no soluble zinc (Mount St. Helens ash, MSH); or c) whole-combustion PM suspension containing 14.5 microg/mg of water-soluble zinc at high dose (PM-HD) and d ) low dose (PM-LD), e) the aqueous fraction of this suspension (14.5 microg/mg of soluble zinc) (PM-L), or f ) zinc sulfate (rats exposed for 8 weeks received double the concentration of all PM components of rats exposed for 16 weeks). Pulmonary inflammation was apparent in all exposure groups when compared with saline (8 weeks > 16 weeks). PM with or without zinc, or with zinc alone caused small increases in focal subepicardial inflammation, degeneration, and fibrosis. Lesions were not detected in controls at 8 weeks but were noted at 16 weeks. We analyzed mitochondrial DNA damage using quantitative polymerase chain reaction and found that all groups except MSH caused varying degrees of damage relative to control. Total cardiac aconitase activity was inhibited in rats receiving soluble zinc. Expression array analysis of heart tissue revealed modest changes in mRNA for genes involved in signaling, ion channels function, oxidative stress, mitochondrial fatty acid metabolism, and cell cycle regulation in zinc but not in MSH-exposed rats. These results suggest that water-soluble PM-associated zinc may be one of the causal components involved in PM cardiac effects. JF - Environmental health perspectives AU - Kodavanti, Urmila P AU - Schladweiler, Mette C AU - Gilmour, Peter S AU - Wallenborn, J Grace AU - Mandavilli, Bhaskar S AU - Ledbetter, Allen D AU - Christiani, David C AU - Runge, Marschall S AU - Karoly, Edward D AU - Costa, Daniel L AU - Peddada, Shyamal AU - Jaskot, Richard AU - Richards, Judy H AU - Thomas, Ronald AU - Madamanchi, Nageswara R AU - Nyska, Abraham AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27710, USA. kodavanti.urmila@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 13 EP - 20 VL - 116 IS - 1 SN - 0091-6765, 0091-6765 KW - Air Pollutants KW - 0 KW - DNA, Mitochondrial KW - Particulate Matter KW - Aconitate Hydratase KW - EC 4.2.1.3 KW - Zinc KW - J41CSQ7QDS KW - Index Medicus KW - zinc KW - mitochondria KW - cardiac gene expression profile KW - particulate matter KW - aconitase KW - air pollution KW - Animals KW - Rats, Inbred WKY KW - Oligonucleotide Array Sequence Analysis KW - Aconitate Hydratase -- metabolism KW - DNA Damage KW - Inflammation -- chemically induced KW - Lung -- pathology KW - Rats KW - Gene Expression Profiling KW - Lung -- drug effects KW - Mitochondria, Heart -- metabolism KW - Bronchoalveolar Lavage Fluid -- cytology KW - Male KW - DNA, Mitochondrial -- genetics KW - Inflammation -- pathology KW - Particulate Matter -- toxicity KW - Heart Diseases -- chemically induced KW - Zinc -- toxicity KW - Heart Diseases -- genetics KW - Heart Diseases -- metabolism KW - Air Pollutants -- toxicity KW - Heart Diseases -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70206218?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=The+role+of+particulate+matter-associated+zinc+in+cardiac+injury+in+rats.&rft.au=Kodavanti%2C+Urmila+P%3BSchladweiler%2C+Mette+C%3BGilmour%2C+Peter+S%3BWallenborn%2C+J+Grace%3BMandavilli%2C+Bhaskar+S%3BLedbetter%2C+Allen+D%3BChristiani%2C+David+C%3BRunge%2C+Marschall+S%3BKaroly%2C+Edward+D%3BCosta%2C+Daniel+L%3BPeddada%2C+Shyamal%3BJaskot%2C+Richard%3BRichards%2C+Judy+H%3BThomas%2C+Ronald%3BMadamanchi%2C+Nageswara+R%3BNyska%2C+Abraham&rft.aulast=Kodavanti&rft.aufirst=Urmila&rft.date=2008-01-01&rft.volume=116&rft.issue=1&rft.spage=13&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.10379 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-25 N1 - Date created - 2008-01-16 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Jpn Circ J. 1987 May;51(5):573-88 [3626016] Toxicol Sci. 2007 Jul;98(1):231-9 [17434951] Biol Trace Elem Res. 1993 Feb;36(2):203-8 [7681312] Am J Physiol. 1999 Sep;277(3 Pt 2):H956-62 [10484416] Biofactors. 2004;20(3):139-45 [15665384] Biochemistry (Mosc). 2005 Feb;70(2):128-36 [15807649] Biochem Biophys Res Commun. 2005 Jul 8;332(3):853-8 [15913554] Environ Health Perspect. 2005 Nov;113(11):1561-8 [16263512] Toxicol Appl Pharmacol. 2006 Feb 15;211(1):41-52 [16005037] J Biol Inorg Chem. 2006 Mar;11(2):131-8 [16391944] Bioinformatics. 2006 Apr 1;22(7):897-9 [16455752] Toxicol Sci. 2006 May;91(1):237-46 [16449252] Proc Soc Exp Biol Med. 1999 Dec;222(3):263-73 [10601885] J Nutr. 2000 Feb;130(2S Suppl):489S-492S [10721936] Sci Total Environ. 2000 Apr 17;249(1-3):85-101 [10813449] J Nutr. 2000 May;130(5S Suppl):1455S-8S [10801959] Toxicol Appl Pharmacol. 2000 Jul 15;166(2):111-9 [10896852] Methods. 2000 Oct;22(2):135-47 [11020328] Brain Res. 2000 Dec 1;885(1):45-52 [11121528] Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2317-22 [11226237] Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11749-54 [11573009] Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12325-7 [11675482] J Cell Sci. 2001 Nov;114(Pt 22):4051-61 [11739637] Nucleic Acids Res. 2002 Jan 1;30(1):207-10 [11752295] Methods Mol Biol. 2002;197:159-76 [12013794] Free Radic Biol Med. 2002 Jun 15;32(12):1237-43 [12057761] Toxicol Sci. 2002 Nov;70(1):73-85 [12388837] Toxicol Sci. 2003 Feb;71(2):237-45 [12563109] Biotechniques. 2003 Feb;34(2):374-8 [12613259] Life Sci. 2000 Jun 30;67(6):627-34 [12659168] J Neurochem. 2003 May;85(3):563-70 [12694382] Environ Health Perspect. 2003 Jun;111(7):972-80 [12782501] Toxicol Appl Pharmacol. 2003 Aug 15;191(1):86-93 [12915106] Circulation. 2004 Jan 6;109(1):71-7 [14676145] Biochemistry. 2004 Mar 30;43(12):3301-9 [15035601] Environ Health Perspect. 2004 May;112(7):792-8 [15159208] Environ Int. 2004 Oct;30(8):1009-17 [15337346] Environ Sci Technol. 2004 Aug 1;38(15):4206-14 [15352462] Genome Biol. 2004;5(10):R80 [15461798] J Nutr. 1984 May;114(5):813-22 [6327957] Lab Anim Sci. 1986 Jun;36(3):256-61 [3724050] J Trace Elem Med Biol. 2006;20(1):3-18 [16632171] Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1419-41 [16987000] J Toxicol Environ Health A. 2006 Nov;69(22):2011-32 [17074742] Biogerontology. 2006 Oct-Dec;7(5-6):399-408 [17048072] J Biol Chem. 2006 Nov 17;281(46):34803-9 [16980308] Clin Occup Environ Med. 2006;5(4):849-64 [17110296] Neurochem Int. 2007 Mar;50(4):591-600 [17250928] Environ Health Perspect. 2007 Jan;115(1):13-9 [17366813] Biometals. 2007 Jun;20(3-4):549-64 [17205209] Sci Total Environ. 1988 Jan;68:25-43 [3363319] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1289/ehp.10379 ER - TY - JOUR T1 - What can epidemiology tell us about risks at low doses? AN - 70172493; 18159960 AB - Puskin, J. S. What Can Epidemiology Tell Us about Risks at Low Doses? Radiat. Res. 169, 122-124 (2008). Limitations on statistical power preclude direct detection and quantification of radiogenic cancer risks at very low (environmental) levels of low-LET radiation through epidemiological studies. Given this limitation and our incomplete understanding of cellular processes leading to radiation carcinogenesis, an "effective threshold" in the dose range of interest for radiation protection cannot yet be ruled out. Ongoing epidemiological studies of chronically exposed individuals receiving very low daily doses of radiation can be used, however, together with radiobiological data, to critically test whether such a threshold is plausible. JF - Radiation research AU - Puskin, J S AD - Radiation Protection Division, U.S. Environmental Protection Agency, Washington, DC 20460, USA. puskin.jerome@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 122 EP - 124 VL - 169 IS - 1 SN - 0033-7587, 0033-7587 KW - Index Medicus KW - Space life sciences KW - Humans KW - Risk Assessment -- statistics & numerical data KW - Environmental Exposure -- statistics & numerical data KW - Dose-Response Relationship, Radiation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70172493?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiation+research&rft.atitle=What+can+epidemiology+tell+us+about+risks+at+low+doses%3F&rft.au=Puskin%2C+J+S&rft.aulast=Puskin&rft.aufirst=J&rft.date=2008-01-01&rft.volume=169&rft.issue=1&rft.spage=122&rft.isbn=&rft.btitle=&rft.title=Radiation+research&rft.issn=00337587&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-15 N1 - Date created - 2007-12-27 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Radiat Res. 2008 Jul;170(1):139-40; author reply 140-1 [18582162] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Multimedia measurements and activity patterns in an observational pilot study of nine young children. AN - 70158642; 17851450 AB - A pilot observational exposure study was performed to evaluate methods for collecting multimedia measurements (air, dust, food, urine) and activity patterns to assess potential exposures of young children to pesticides in their homes. Nine children (mean age=5 years) and their caregivers participated in this study, performed in the Duval County, Florida, in collaboration with the Centers for Disease Control and Prevention and the Duval County Health Department. For all nine children, the total time reported for sleeping and napping ranged from 9.5 to 14 h per day, indoor quiet time from 0 to 5.5 h per day, indoor active time from 0.75 to 5.5 h per day, outdoor quiet time from 0 to 1.5 h per day, and outdoor active time from 0.5 to 6.5 h per day. Each home had one to three pesticide products present, with aerosols being most common. Pesticide inventories, however, were not useful for predicting pesticide levels in the home. Synthetic pyrethroids were the most frequently identified active ingredients in the products present in each home. Fifteen pesticide active ingredients were measured in the application area wipes (not detected (ND) to 580 ng/cm(2)), 13 in the play area wipes (ND-117 ng/cm(2)), and 14 in the indoor air samples (ND-378 ng/m(3)) and the socks (ND-1000 ng/cm(2)). Cis-permethrin, trans-permethrin, and cypermethrin were measured in all nine homes. Chlorpyrifos was measured in all nine homes even though it was not reported used by the participants. All urine samples contained measurable concentrations of 3-phenoxybenzoic acid (3-PBA). The median 3-PBA urinary concentration for the nine children was 2.2 mug/l. A wide variety of pesticide active ingredients were measured in these nine homes at median concentrations that were often higher than reported previously in similar studies. These data highlight the need for additional observational studies in regions where pesticides are used in order to understand the factors that affect young children's exposures and the education/mitigation strategies that can be used to reduce children's exposures. JF - Journal of exposure science & environmental epidemiology AU - Tulve, Nicolle S AU - Egeghy, Peter P AU - Fortmann, Roy C AU - Whitaker, Donald A AU - Nishioka, Marcia G AU - Naeher, Luke P AU - Hilliard, Aaron AD - National Exposure Research Laboratory, US EPA, MD-E205-04, Research Triangle Park, NC 27711, USA. tulve.nicolle@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 31 EP - 44 VL - 18 IS - 1 KW - Environmental Pollutants KW - 0 KW - Pesticides KW - Pyrethrins KW - cypermethrin KW - 1TR49121NP KW - Permethrin KW - 509F88P9SZ KW - Index Medicus KW - Humans KW - Food Contamination KW - Pilot Projects KW - Child KW - Geography KW - Time Factors KW - Florida KW - Risk Assessment KW - Child, Preschool KW - Environmental Pollutants -- toxicity KW - Pyrethrins -- urine KW - Pyrethrins -- toxicity KW - Pesticides -- urine KW - Environmental Exposure KW - Permethrin -- urine KW - Environmental Pollutants -- urine KW - Permethrin -- toxicity KW - Pesticides -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70158642?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+exposure+science+%26+environmental+epidemiology&rft.atitle=Multimedia+measurements+and+activity+patterns+in+an+observational+pilot+study+of+nine+young+children.&rft.au=Tulve%2C+Nicolle+S%3BEgeghy%2C+Peter+P%3BFortmann%2C+Roy+C%3BWhitaker%2C+Donald+A%3BNishioka%2C+Marcia+G%3BNaeher%2C+Luke+P%3BHilliard%2C+Aaron&rft.aulast=Tulve&rft.aufirst=Nicolle&rft.date=2008-01-01&rft.volume=18&rft.issue=1&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Journal+of+exposure+science+%26+environmental+epidemiology&rft.issn=1559-064X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-18 N1 - Date created - 2007-12-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Modeling population exposures to outdoor sources of hazardous air pollutants. AN - 70153129; 17878926 AB - Accurate assessment of human exposures is an important part of environmental health effects research. However, most air pollution epidemiology studies rely upon imperfect surrogates of personal exposures, such as information based on available central-site outdoor concentration monitoring or modeling data. In this paper, we examine the limitations of using outdoor concentration predictions instead of modeled personal exposures for over 30 gaseous and particulate hazardous air pollutants (HAPs) in the US. The analysis uses the results from an air quality dispersion model (the ASPEN or Assessment System for Population Exposure Nationwide model) and an inhalation exposure model (the HAPEM or Hazardous Air Pollutant Exposure Model, Version 5), applied by the US. Environmental protection Agency during the 1999 National Air Toxic Assessment (NATA) in the US. Our results show that the total predicted chronic exposure concentrations of outdoor HAPs from all sources are lower than the modeled ambient concentrations by about 20% on average for most gaseous HAPs and by about 60% on average for most particulate HAPs (mainly, due to the exclusion of indoor sources from our modeling analysis and lower infiltration of particles indoors). On the other hand, the HAPEM/ASPEN concentration ratio averages for onroad mobile source exposures were found to be greater than 1 (around 1.20) for most mobile-source related HAPs (e.g. 1, 3-butadiene, acetaldehyde, benzene, formaldehyde) reflecting the importance of near-roadway and commuting environments on personal exposures to HAPs. The distribution of the ratios of personal to ambient concentrations was found to be skewed for a number of the VOCs and reactive HAPs associated with major source emissions, indicating the importance of personal mobility factors. We conclude that the increase in personal exposures from the corresponding predicted ambient levels tends to occur near locations where there are either major emission sources of HAPs or when individuals are exposed to either on- or nonroad sources of HAPs during their daily activities. These findings underscore the importance of applying exposure-modeling methods, which incorporate information on time-activity, commuting, and exposure factors data, for the purposes of assigning exposures in air pollution health studies. JF - Journal of exposure science & environmental epidemiology AU - Ozkaynak, Halûk AU - Palma, Ted AU - Touma, Jawad S AU - Thurman, James AD - National Exposure Research Laboratory, US Environmental Protection Agency, NC 27711, USA. ozkaynak.haluk@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 45 EP - 58 VL - 18 IS - 1 KW - Air Pollutants KW - 0 KW - Hazardous Substances KW - Organic Chemicals KW - Index Medicus KW - United States KW - Population Groups KW - United States Environmental Protection Agency KW - Particle Size KW - Humans KW - Volatilization KW - Time Factors KW - Models, Biological KW - Air Movements KW - Risk Assessment KW - Public Health KW - Organic Chemicals -- toxicity KW - Environmental Exposure KW - Organic Chemicals -- analysis KW - Air Pollutants -- analysis KW - Air Pollutants -- toxicity KW - Hazardous Substances -- analysis KW - Hazardous Substances -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70153129?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+exposure+science+%26+environmental+epidemiology&rft.atitle=Modeling+population+exposures+to+outdoor+sources+of+hazardous+air+pollutants.&rft.au=Ozkaynak%2C+Hal%C3%BBk%3BPalma%2C+Ted%3BTouma%2C+Jawad+S%3BThurman%2C+James&rft.aulast=Ozkaynak&rft.aufirst=Hal%C3%BBk&rft.date=2008-01-01&rft.volume=18&rft.issue=1&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Journal+of+exposure+science+%26+environmental+epidemiology&rft.issn=1559-064X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-18 N1 - Date created - 2007-12-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Exposure of Americans to polybrominated diphenyl ethers. AN - 70153084; 17426733 AB - Polybrominated diphenyl ethers, PBDEs, are a class of brominated flame retardants that, like other persistent organic pollutants (POPs), have been found in humans, wildlife, and biota worldwide. Unlike other POPs, however, the key routes of human exposure are not thought to be food and fish, but rather are from their use in household consumer products, and to the high levels of PBDEs found in house dust. The exposure of Americans to PBDEs was systematically evaluated in this study. First, exposure media data on PBDE congeners were compiled. Then, an adult intake dose was derived using exposure factors in combination with these data. The exposure pathways evaluated included food and water ingestion, inhalation, and ingestion and dermal contact to house dust. These intakes were converted to a body burden using a simple pharmacokinetic (PK) model. The predicted body burdens were compared with representative profiles of PBDEs in blood and milk. The adult intake dose of total PBDEs was estimated to be 7.7 ng/kg body weight/day, and children's estimated intakes were higher at 49.3 ng/kg/day for ages 1-5, 14.4 ng/kg/day for 6-11, and 9.1 ng/kg/day for 12-19. The much higher dose for the child age 1-5 was due to the doubling of dust ingestion from 50 to 100 mg/day. The predicted adult body burden of total PBDEs was 33.8 ng/kg lipid weight (lwt), compared to representative measurements in blood and milk at 64.0 and 93.7 ng/g lwt, respectively Most of this apparent underprediction in total concentration was due to an underprediction of the key congener, BDE 47. The value for BDE 47 half-life in the body was identified as the variable most likely in error in this exercise. Other congener predictions compared well with measurements, suggesting general validity with the approach. An important finding from this assessment is that the food intake estimate of about 1.3 ng/kg/day (of the 7.7 ng/kg/day total) cannot explain current US body burdens; exposures to PBDEs in house dust accounted for 82% of the overall estimated intakes. JF - Journal of exposure science & environmental epidemiology AU - Lorber, Matthew AD - Office of Research and Development, United States Environmental Protection Agency, 1200 Pennsylvania Ave, NW, Washington, DC, USA. lorber.matthew@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 2 EP - 19 VL - 18 IS - 1 KW - Dust KW - 0 KW - Flame Retardants KW - Lipids KW - Polybrominated Biphenyls KW - Index Medicus KW - United States KW - Animals KW - Housing KW - Air Pollution, Indoor KW - Body Burden KW - Humans KW - Risk Assessment KW - Eating KW - Public Health KW - Flame Retardants -- pharmacokinetics KW - Time Factors KW - Flame Retardants -- toxicity KW - Lipids -- blood KW - Polybrominated Biphenyls -- blood KW - Lipids -- pharmacokinetics KW - Polybrominated Biphenyls -- pharmacokinetics KW - Environmental Exposure KW - Polybrominated Biphenyls -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70153084?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+exposure+science+%26+environmental+epidemiology&rft.atitle=Exposure+of+Americans+to+polybrominated+diphenyl+ethers.&rft.au=Lorber%2C+Matthew&rft.aulast=Lorber&rft.aufirst=Matthew&rft.date=2008-01-01&rft.volume=18&rft.issue=1&rft.spage=2&rft.isbn=&rft.btitle=&rft.title=Journal+of+exposure+science+%26+environmental+epidemiology&rft.issn=1559-064X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-18 N1 - Date created - 2007-12-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Mechanistic considerations for formaldehyde-induced bronchoconstriction involving S-nitrosoglutathione reductase. AN - 70152244; 18097950 AB - Inhalation of formaldehyde vapor has long been suspected of producing airway pathophysiology such as asthma and hyperresponsivity, presumably via irritant mechanisms. Recent studies on asthma and airway biology implicate changes in nitric oxide (NO) disposition in the adverse effects of formaldehyde, principally because enzymatic reduction of the endogenous bronchodilator S-nitrosoglutathione (GSNO) is dependent upon GSNO reductase (formally designated as alcohol dehydrogenase-3, ADH3), which also serves as the primary enzyme for cellular detoxification of formaldehyde. Considering recent evidence that regulation of bronchodilators like GSNO might play a more important role in asthma than inflammation per se, formaldehyde also needs to be considered as influencing ADH3-mediated GSNO catabolism. This is due to changes in ADH3 cofactors and thiol redox state among several potential mechanisms. Data suggest that deregulation of GSNO turnover provides a plausible, enzymatically based mechanism by which formaldehyde might exacerbate asthma and induce bronchoconstriction. JF - Journal of toxicology and environmental health. Part A AU - Thompson, Chad M AU - Grafström, Roland C AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, USA. Y1 - 2008 PY - 2008 DA - 2008 SP - 244 EP - 248 VL - 71 IS - 3 SN - 1528-7394, 1528-7394 KW - Disinfectants KW - 0 KW - Formaldehyde KW - 1HG84L3525 KW - Aldehyde Oxidoreductases KW - EC 1.2.- KW - formaldehyde dehydrogenase, glutathione-independent KW - EC 1.2.1.46 KW - Index Medicus KW - Animals KW - Humans KW - Disinfectants -- adverse effects KW - Aldehyde Oxidoreductases -- physiology KW - Asthma -- enzymology KW - Formaldehyde -- adverse effects KW - Aldehyde Oxidoreductases -- metabolism KW - Asthma -- chemically induced KW - Bronchoconstriction -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70152244?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Mechanistic+considerations+for+formaldehyde-induced+bronchoconstriction+involving+S-nitrosoglutathione+reductase.&rft.au=Thompson%2C+Chad+M%3BGrafstr%C3%B6m%2C+Roland+C&rft.aulast=Thompson&rft.aufirst=Chad&rft.date=2008-01-01&rft.volume=71&rft.issue=3&rft.spage=244&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-10 N1 - Date created - 2007-12-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Potential new approaches for children's inhalation risk assessment. AN - 70151550; 18097946 AB - The U.S. Environmental Protection Agency (EPA) practice of risk assessment is moving toward more thoroughly considering children's unique susceptibilities and exposure potential. Childhood is assessed as a sequence of life stages that reflects the fact that as humans develop, windows of susceptibility may appear that lead to enhanced sensitivity to exposure of environmental agents, while changes in behavior and physiology may increase exposure and dose. The U.S. EPA developed guidance in the past few years that addresses some aspects of increased susceptibility and exposure and dose. However, when it comes to considering inhalation exposure, dose, and risk, current U.S. EPA practice does not explicitly address children. The purpose here is to begin studying the adequacy of practice for children's health and to explore possible next steps in developing new methods to more accurately assess life-stage-specific differences. The existing guidelines and policies used to address potentially unique susceptibilities of children for inhaled environmental chemicals were considered, as well as what may be learned from examples of approaches that have been applied by state agencies (such as the California Environmental Protection Agency) or in the literature, to incorporate potentially unique susceptibilities and exposures to children. Finally, there is a discussion of possible approaches for considering inhalation exposure and susceptibility in U.S. EPA risk assessments. JF - Journal of toxicology and environmental health. Part A AU - Firestone, Michael AU - Sonawane, Babasaheb AU - Barone, Stanley AU - Salmon, Andrew G AU - Brown, Joseph P AU - Hattis, Dale AU - Woodruff, Tracey AD - Office of Children's Health Protection and Environmental Education, U.S. Environmental Protection Agency, Washington, DC 20460, USA. firestone.michael@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 208 EP - 217 VL - 71 IS - 3 SN - 1528-7394, 1528-7394 KW - Air Pollutants KW - 0 KW - Carcinogens KW - Index Medicus KW - United States KW - Animals KW - Humans KW - Adult KW - Male KW - Female KW - Pregnancy KW - Child, Preschool KW - United States Environmental Protection Agency KW - Inhalation Exposure KW - Disease Models, Animal KW - Risk Assessment -- methods KW - Air Pollutants -- adverse effects KW - Neoplasms -- etiology KW - Prenatal Exposure Delayed Effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70151550?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Potential+new+approaches+for+children%27s+inhalation+risk+assessment.&rft.au=Firestone%2C+Michael%3BSonawane%2C+Babasaheb%3BBarone%2C+Stanley%3BSalmon%2C+Andrew+G%3BBrown%2C+Joseph+P%3BHattis%2C+Dale%3BWoodruff%2C+Tracey&rft.aulast=Firestone&rft.aufirst=Michael&rft.date=2008-01-01&rft.volume=71&rft.issue=3&rft.spage=208&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-10 N1 - Date created - 2007-12-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Cancer mortality in a Chinese population exposed to hexavalent chromium in drinking water. AN - 70149690; 18091413 AB - In 1987, investigators in Liaoning Province, China, reported that mortality rates for all cancer, stomach cancer, and lung cancer in 1970-1978 were higher in villages with hexavalent chromium (Cr+6)-contaminated drinking water than in the general population. The investigators reported rates, but did not report statistical measures of association or precision. Using reports and other communications from investigators at the local Jinzhou Health and Anti-Epidemic Station, we obtained data on Cr+6 contamination of groundwater and cancer mortality in 9 study regions near a ferrochromium factory. We estimated: (1) person-years at risk in the study regions, based on census and population growth rate data, (2) mortality counts, based on estimated person-years at risk and previously reported mortality rates, and (3) rate ratios and 95% confidence intervals. The all-cancer mortality rate in the combined 5 study regions with Cr+6-contaminated water was negligibly elevated in comparison with the rate in the 4 combined study regions without contaminated water (rate ratio = 1.13; 95% confidence interval = 0.86-1.46), but was somewhat more elevated in comparison with the whole province (1.23; 0.97-1.53). Stomach cancer mortality in the regions with contaminated water was more substantially elevated in comparison with the regions without contaminated water (1.82; 1.11-2.91) and the whole province (1.69; 1.12-2.44). Lung cancer mortality was slightly elevated in comparison with the unexposed study regions (1.15; 0.62-2.07), and more strongly elevated in comparison with the whole province (1.78; 1.03-2.87). Mortality from other cancers combined was not elevated in comparison with either the unexposed study regions (0.86; 0.53-1.36) or the whole province (0.92; 0.58-1.38). While these data are limited, they are consistent with increased stomach cancer risk in a population exposed to Crz=6 in drinking water. JF - Epidemiology (Cambridge, Mass.) AU - Beaumont, James J AU - Sedman, Richard M AU - Reynolds, Stephen D AU - Sherman, Claire D AU - Li, Ling-Hong AU - Howd, Robert A AU - Sandy, Martha S AU - Zeise, Lauren AU - Alexeeff, George V AD - California Environmental Protection Agency, Office of Environmental Health Hazard Assessment, Sacramento and Oakland, California 95812-4010, USA. jbeaumont@oehha.ca.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 12 EP - 23 VL - 19 IS - 1 SN - 1044-3983, 1044-3983 KW - Water Pollutants, Chemical KW - 0 KW - Chromium KW - 0R0008Q3JB KW - chromium hexavalent ion KW - 18540-29-9 KW - Index Medicus KW - Odds Ratio KW - Humans KW - China -- epidemiology KW - Retrospective Studies KW - Water Supply -- analysis KW - Water Pollutants, Chemical -- analysis KW - Stomach Neoplasms -- mortality KW - Chromium -- analysis KW - Water Pollutants, Chemical -- toxicity KW - Lung Neoplasms -- mortality KW - Chromium -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70149690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+%28Cambridge%2C+Mass.%29&rft.atitle=Cancer+mortality+in+a+Chinese+population+exposed+to+hexavalent+chromium+in+drinking+water.&rft.au=Beaumont%2C+James+J%3BSedman%2C+Richard+M%3BReynolds%2C+Stephen+D%3BSherman%2C+Claire+D%3BLi%2C+Ling-Hong%3BHowd%2C+Robert+A%3BSandy%2C+Martha+S%3BZeise%2C+Lauren%3BAlexeeff%2C+George+V&rft.aulast=Beaumont&rft.aufirst=James&rft.date=2008-01-01&rft.volume=19&rft.issue=1&rft.spage=12&rft.isbn=&rft.btitle=&rft.title=Epidemiology+%28Cambridge%2C+Mass.%29&rft.issn=10443983&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-15 N1 - Date created - 2007-12-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Epidemiology. 2008 Jan;19(1):1-2 [18091410] Epidemiology. 2008 Jan;19(1):24-6 [18091414] Epidemiology. 2009 Jul;20(4):627-8; author reply 628 [19525697] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The afterlife of drugs and the role of pharmEcovigilance. AN - 69819258; 19026025 AB - The prescribing and usage of medications (for both humans and domestic animals) have ramifications extending far beyond the traditional objectives of conventional medical care. The healthcare industry has an environmental footprint that includes the active pharmaceutical ingredients (APIs) from medications, residues of which can establish themselves as environmental pollutants. This occurs by a variety of routes, but primarily from excretion, bathing and disposal. Many parallels exist between healthcare and the protection and remediation of the environment, spanning the stages from symptomology and diagnosis to treatment. The critical role played by pharmacovigilance in healthcare has a counterpart with the ecological environment. The term ecopharmacovigilance has been used with respect to the unforeseen consequences APIs can have once they enter the environment. We propose that conventional pharmacovigilance could be expanded to encompass environmental concerns--a concept we term pharmEcovigilance--as a way to unify the parallel but interconnected needs for protecting both human and ecological health.To convey the scope of a pharmEcovigilance programme, we provide an overview of the occurrence of APIs as environmental pollutants, their ramifications for human health and the environment and some of the ways in which their impact could be reduced or minimized. The major areas discussed include: (i) the routes by which APIs become contaminants in the environment; (ii) the hazards of leftover drugs as a result of stockpiling and from disposal to sewage, which can also eventually contribute to the contamination of drinking water; (iii) why drugs accumulate unused; and (iv) the benefits for humans and the environment that could accrue from reducing the accumulation of leftover drugs and the subsequent introduction of APIs into the environment. A broad spectrum of actions could be taken by prescribers (including veterinarians) and the healthcare industry at large (including manufacturers and insurers) to reduce the release or introduction of APIs to the environment. Most significantly, however, a major reason to consider implementing a pharmEcovigilance programme--beyond reducing the environmental footprint of healthcare--is the previously unforeseen collateral benefit in making further progress in optimizing the delivery, effectiveness, outcomes and cost of healthcare, as well as improving safety for humans, pets and wildlife. For this reason, the relationships that healthcare professionals and patients have with medications might also include consideration of pharmEcovigilance. Like any profession that deals with chemicals, perhaps a major challenge to be faced is how to ensure the sustainability (and minimize the life cycle exposure hazards) of a chemical-based, chemical-centric society in the most cost-effective and safest manner. Given that the medical community is a major source of numerous 'exotic' chemical pollutants in the environment (with thousands of chemically distinct APIs in current use), albeit at very low levels, an imperative could be created for designing and implementing approaches for reducing and controlling this source of pollution. With reduced wastage of medications, in part driven by appropriate or rational prescribing and dispensing, the ecological footprint of medicine could be greatly reduced, with concomitant improvements in many aspects of healthcare. JF - Drug safety AU - Daughton, Christian G AU - Ruhoy, Ilene Sue AD - Environmental Chemistry Branch, National Exposure Research Laboratory, US Environmental Protection Agency, Las Vegas, Nevada 89119, USA. daughton.christian@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1069 EP - 1082 VL - 31 IS - 12 SN - 0114-5916, 0114-5916 KW - Environmental Pollutants KW - 0 KW - Prescription Drugs KW - Index Medicus KW - Refuse Disposal -- methods KW - Humans KW - Physician's Role KW - Environmental Pollutants -- adverse effects KW - Environmental Pollution -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69819258?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Drug+safety&rft.atitle=The+afterlife+of+drugs+and+the+role+of+pharmEcovigilance.&rft.au=Daughton%2C+Christian+G%3BRuhoy%2C+Ilene+Sue&rft.aulast=Daughton&rft.aufirst=Christian&rft.date=2008-01-01&rft.volume=31&rft.issue=12&rft.spage=1069&rft.isbn=&rft.btitle=&rft.title=Drug+safety&rft.issn=01145916&rft_id=info:doi/10.2165%2F0002018-200831120-00004 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-03-05 N1 - Date created - 2008-11-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.2165/0002018-200831120-00004 ER - TY - JOUR T1 - Evaluation of the role of peroxisome proliferator-activated receptor alpha (PPARalpha) in mouse liver tumor induction by trichloroethylene and metabolites. AN - 69790165; 18821149 AB - Trichloroethylene (TCE) is an industrial solvent and a widespread environmental contaminant. Induction of liver cancer in mice by TCE is thought to be mediated by two metabolites, dichloroacetate (DCA) and trichloroacetate (TCA), both of which are themselves mouse liver carcinogens. TCE, TCA, and DCA are relatively weak peroxisome proliferators (PP), a group of rodent hepatocarcinogens that activate a nuclear receptor, PP-activated receptor alpha (PPARalpha. The objective of this review is to assess the weight of evidence (WOE) that PPARalpha is or is not mechanistically involved in mouse liver tumor induction by TCE and metabolites. Based on similarities of TCE and TCA to typical PP, including dose-response characteristics showing PPARalpha-dependent responses coincident with liver tumor induction and abolishment of TCE and TCA effects in PPARalpha-null mice, the WOE supports the hypothesis that PPARalpha plays a dominant role in TCE- and TCA-induced hepatocarcinogenesis. Data indicates that the MOA for DCA tumor induction is PPARalpha-independent. Uncertainties remain regarding the genesis of the TCE-induced tumors. In contrast to the TCA-induced tumors, which have molecular features similar to those induced by typical PP, there is evidence, albeit weak, that TCE tumors arise by a mode of action (MOA) different from that of TCA tumors, based largely on dissimilarities in molecular markers found in TCE versus TCA-induced tumors. In summary, the WOE indicates that TCA-induced liver tumors arise by a PPARalpha-dependent MOA. Although the TCE MOA is likely dominated by a PPARalpha-dependent contribution from TCA, the contribution of a PPARalpha-independent MOA from DCA cannot be ruled out. JF - Critical reviews in toxicology AU - Corton, J Christopher AD - National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. corton.chris@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 857 EP - 875 VL - 38 IS - 10 KW - Environmental Pollutants KW - 0 KW - Peroxisome Proliferator-Activated Receptors KW - Trichloroethylene KW - 290YE8AR51 KW - Trichloroacetic Acid KW - 5V2JDO056X KW - Dichloroacetic Acid KW - 9LSH52S3LQ KW - Tetrachloroethylene KW - TJ904HH8SN KW - Index Medicus KW - Animals KW - Dichloroacetic Acid -- toxicity KW - Trichloroacetic Acid -- metabolism KW - Trichloroacetic Acid -- toxicity KW - Tetrachloroethylene -- metabolism KW - Dichloroacetic Acid -- metabolism KW - Mice KW - Tetrachloroethylene -- toxicity KW - Trichloroethylene -- metabolism KW - Liver Neoplasms -- pathology KW - Liver Neoplasms -- metabolism KW - Environmental Pollutants -- metabolism KW - Environmental Pollutants -- toxicity KW - Liver Neoplasms -- chemically induced KW - Peroxisome Proliferator-Activated Receptors -- metabolism KW - Trichloroethylene -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69790165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Critical+reviews+in+toxicology&rft.atitle=Evaluation+of+the+role+of+peroxisome+proliferator-activated+receptor+alpha+%28PPARalpha%29+in+mouse+liver+tumor+induction+by+trichloroethylene+and+metabolites.&rft.au=Corton%2C+J+Christopher&rft.aulast=Corton&rft.aufirst=J&rft.date=2008-01-01&rft.volume=38&rft.issue=10&rft.spage=857&rft.isbn=&rft.btitle=&rft.title=Critical+reviews+in+toxicology&rft.issn=1547-6898&rft_id=info:doi/10.1080%2F10408440802209796 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-01-19 N1 - Date created - 2008-11-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/10408440802209796 ER - TY - JOUR T1 - Application of QSARs and VFARs to the rapid risk assessment process at US EPA. AN - 69660187; 18853303 AB - With continued development of new chemicals and genetically engineered microbes as potential agents for terrorism and industrial development, there is a great need for the continued development and application of quantitative structure activity relationships (QSARs) and virulence factor activity relationships (VFARs). Development and application of QSARs and VFARs will facilitate efficient and streamlined use of dwindling resources and assessment of risks associated with exposures to chemical and biological agents. To facilitate the continued development of QSARs and VFARs at US Environmental Protection Agency, a two day workshop was organized June 20-21, 2006, in Cincinnati, OH, USA. This article summarizes the workshop report by highlighting the importance of continued QSAR research, the current state of VFAR science, and the guidance provided to the National Homeland Security Research Center and National Risk Management Research Laboratory by an expert panel for the continued use and development of computational approaches. JF - SAR and QSAR in environmental research AU - Moudgal, C J AU - Young, D AU - Nichols, T AU - Martin, T AU - Harten, P AU - Venkatapathy, R AU - Stelma, G AU - Siddhanti, S AU - Baier-Anderson, C AU - Wolfe, M AD - US EPA, TCAD, NHSRC, ENSV/IO, Kansas City, KS, USA. moudgal.chandrika@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 579 EP - 587 VL - 19 IS - 5-6 KW - Environmental Pollutants KW - 0 KW - Virulence Factors KW - Index Medicus KW - United States KW - United States Environmental Protection Agency KW - Environmental Health KW - Humans KW - Databases, Factual KW - Information Management KW - Environmental Pollutants -- toxicity KW - Quantitative Structure-Activity Relationship KW - Safety Management -- methods KW - Virulence Factors -- toxicity KW - Risk Assessment -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69660187?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=SAR+and+QSAR+in+environmental+research&rft.atitle=Application+of+QSARs+and+VFARs+to+the+rapid+risk+assessment+process+at+US+EPA.&rft.au=Moudgal%2C+C+J%3BYoung%2C+D%3BNichols%2C+T%3BMartin%2C+T%3BHarten%2C+P%3BVenkatapathy%2C+R%3BStelma%2C+G%3BSiddhanti%2C+S%3BBaier-Anderson%2C+C%3BWolfe%2C+M&rft.aulast=Moudgal&rft.aufirst=C&rft.date=2008-01-01&rft.volume=19&rft.issue=5-6&rft.spage=579&rft.isbn=&rft.btitle=&rft.title=SAR+and+QSAR+in+environmental+research&rft.issn=1029-046X&rft_id=info:doi/10.1080%2F10629360802348944 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-12-19 N1 - Date created - 2008-10-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/10629360802348944 ER - TY - JOUR T1 - Integrated disinfection by-products (DBP) mixtures research: gene expression alterations in primary rat hepatocyte cultures exposed to DBP mixtures formed by chlorination and ozonation/postchlorination. AN - 69321710; 18636392 AB - Large-scale differential gene expression analysis was used to examine the biological effects of disinfected surface waters on cultured rat hepatocytes. Source water from East Fork Lake (Harsha Lake), a reservoir on the Little Miami River in Ohio, was spiked with iodide and bromide and disinfected by chlorination or ozonation/postchlorination. The chlorinated and ozonated/postchlorinated waters were concentrated, respectively, 136- and 124-fold (full strength) by reverse-osmosis membrane techniques. Volatile disinfection by-products (DBP) lost during concentration were restored to the extent possible. Primary rat hepatocytes were exposed to either full-strength or 1:10 or 1:20 dilutions of the concentrates for 24 h and assayed for cytotoxicity and gene expression alterations. The full-strength concentrates were cytotoxic, whereas the diluted samples exhibited no detectable cytotoxicity. Differential gene expression analysis provided evidence for the underlying causes of the severe cytotoxicity observed in rat hepatocytes treated with the full-strength ozonation/postchlorination concentrate (e.g., cell cycle arrest, metabolic stasis, oxidative stress). Many gene expression responses were shared among the hepatocyte cultures treated with dilutions of the ozonation/ postchlorination and chlorination concentrates. The shift in the character of the response between the full-strength concentrates and the diluted samples indicated a threshold for toxicity. A small subset of gene expression changes was identified that was observed in the response of hepatocytes to peroxisome proliferators, phthalate esters, and haloacetic acids, suggesting a peroxisome proliferative response. JF - Journal of toxicology and environmental health. Part A AU - Crosby, Lynn M AU - Simmons, Jane Ellen AU - Ward, William O AU - Moore, Tanya M AU - Morgan, Kevin T AU - Deangelo, Anthony B AD - U.S. Environmental Protection Agency/University of North Carolina-Chapel Hill Cooperative Training Program, Research Triangle Park, North Carolina 27711, USA. Y1 - 2008 PY - 2008 DA - 2008 SP - 1195 EP - 1215 VL - 71 IS - 17 SN - 1528-7394, 1528-7394 KW - Chlorine Compounds KW - 0 KW - Disinfectants KW - Water Pollutants, Chemical KW - Ozone KW - 66H7ZZK23N KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Cells, Cultured KW - Male KW - Chlorine Compounds -- toxicity KW - Hepatocytes -- drug effects KW - Chlorine Compounds -- pharmacology KW - Water Pollutants, Chemical -- pharmacology KW - Halogenation KW - Water Pollutants, Chemical -- analysis KW - Water Pollutants, Chemical -- toxicity KW - Gene Expression Regulation -- drug effects KW - Hepatocytes -- enzymology KW - Disinfectants -- toxicity KW - Ozone -- toxicity KW - Hepatocytes -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69321710?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Integrated+disinfection+by-products+%28DBP%29+mixtures+research%3A+gene+expression+alterations+in+primary+rat+hepatocyte+cultures+exposed+to+DBP+mixtures+formed+by+chlorination+and+ozonation%2Fpostchlorination.&rft.au=Crosby%2C+Lynn+M%3BSimmons%2C+Jane+Ellen%3BWard%2C+William+O%3BMoore%2C+Tanya+M%3BMorgan%2C+Kevin+T%3BDeangelo%2C+Anthony+B&rft.aulast=Crosby&rft.aufirst=Lynn&rft.date=2008-01-01&rft.volume=71&rft.issue=17&rft.spage=1195&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802182581 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-24 N1 - Date created - 2008-07-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15287390802182581 ER - TY - JOUR T1 - Integrated disinfection by-products mixtures research: disinfection of drinking waters by chlorination and ozonation/postchlorination treatment scenarios. AN - 69319241; 18636388 AB - This article describes disinfection of the same source water by two commonly used disinfection treatment scenarios for purposes of subsequent concentration, chemical analysis, and toxicological evaluation. Accompanying articles in this issue of the Journal of Toxicology and Environmental Health describe concentration of these finished waters by reverse osmosis techniques, chemical characterization of the resulting disinfection by-product (DBP) concentrates, in vivo and in vitro toxicological results, and risk assessment methods developed to analyze data from this project. This project, called the "Four Lab Study," involved participation of scientists from four laboratories/centers of the U.S. Environmental Protection Agency Office of Research and Development as well as extramural collaborators from the water industry and academia. One of the two finished waters was prepared by conventional treatment and disinfected by chlorination. The other finished water was also prepared by conventional treatment and disinfected by ozonation followed by chlorination (ozonation/postchlorination). Chlorination conditions of dose, time and temperature were similar for both treatment scenarios, allowing for a comparison. Both finished waters had acceptably low levels of particulates and bacteria, representative pH and chlorine levels, and contained numerous DBP. Known effects of ozonation were observed in that, relative to the water that was chlorinated only, the ozonated/postchlorinated water had lower concentrations of total organic halogen, trihalomethanes (THM), haloacetic acids (HAA), and higher concentrations of bromate, and aldehydes. JF - Journal of toxicology and environmental health. Part A AU - Miltner, Richard J AU - Speth, Thomas F AU - Richardson, Susan D AU - Krasner, Stuart W AU - Weinberg, Howard S AU - Simmons, Jane Ellen AD - National Risk Management Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, USA. miltner.richard@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1133 EP - 1148 VL - 71 IS - 17 SN - 1528-7394, 1528-7394 KW - Disinfectants KW - 0 KW - Hydrocarbons, Halogenated KW - Water Pollutants, Chemical KW - Ozone KW - 66H7ZZK23N KW - Index Medicus KW - United States KW - Animals KW - Filtration KW - Humans KW - Risk Assessment KW - Water Supply -- analysis KW - Hydrocarbons, Halogenated -- toxicity KW - United States Environmental Protection Agency KW - Halogenation KW - Water Pollutants, Chemical -- analysis KW - Water Pollutants, Chemical -- toxicity KW - Disinfectants -- metabolism KW - Hydrocarbons, Halogenated -- analysis KW - Water Purification -- methods KW - Ozone -- chemistry KW - Disinfectants -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69319241?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Integrated+disinfection+by-products+mixtures+research%3A+disinfection+of+drinking+waters+by+chlorination+and+ozonation%2Fpostchlorination+treatment+scenarios.&rft.au=Miltner%2C+Richard+J%3BSpeth%2C+Thomas+F%3BRichardson%2C+Susan+D%3BKrasner%2C+Stuart+W%3BWeinberg%2C+Howard+S%3BSimmons%2C+Jane+Ellen&rft.aulast=Miltner&rft.aufirst=Richard&rft.date=2008-01-01&rft.volume=71&rft.issue=17&rft.spage=1133&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802182060 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-24 N1 - Date created - 2008-07-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15287390802182060 ER - TY - JOUR T1 - Research issues underlying the four-lab study: integrated disinfection by-products mixtures research. AN - 69319140; 18636387 AB - Chemical disinfection of drinking water is a major public health triumph of the 20th century, resulting in significant decreases in morbidity and mortality from waterborne diseases. Disinfection by-products (DBP) are chemicals formed by the reaction of oxidizing disinfectants with inorganic and organic materials in the source water. To address potential health concerns that cannot be answered directly by toxicological research on individual DBPs or defined DBP mixtures, scientists residing within the various organizations of the U.S. Environmental Protection Agency's Office of Research and Development (the National Health and Environmental Effects Research Laboratory, the National Risk Management Research Laboratory, the National Exposure Research Laboratory, and the National Center for Environmental Assessment) engaged in joint investigation of environmentally realistic complex mixtures of DBP. Research on complex mixtures of DBP is motivated by three factors: (a) DBP exposure is ubiquitous to all segments of the population; (b) some positive epidemiologic studies are suggestive of potential developmental, reproductive, or carcinogenic health effects in humans exposed to DBP; and (c) significant amounts of the material that makes up the total organic halide portion of the DBP have not been identified. The goal of the Integrated Disinfection Byproducts Mixtures Research Project (the 4Lab Study) is provision of sound, defensible, experimental data on environmentally relevant mixtures of DBP and an improved estimation of the potential health risks associated with exposure to the mixtures of DBP formed during disinfection of drinking water. A phased research plan was developed and implemented. The present series of articles provides the results from the first series of experiments. JF - Journal of toxicology and environmental health. Part A AU - Simmons, Jane Ellen AU - Richardson, Susan D AU - Teuschler, Linda K AU - Miltner, Richard J AU - Speth, Thomas F AU - Schenck, Kathleen M AU - Hunter, E Sidney AU - Rice, Glenn AD - National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC, USA. Simmons.Jane@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1125 EP - 1132 VL - 71 IS - 17 SN - 1528-7394, 1528-7394 KW - Disinfectants KW - 0 KW - Index Medicus KW - United States KW - Animals KW - United States Environmental Protection Agency KW - Humans KW - Interprofessional Relations KW - Public Health KW - Disinfectants -- chemistry KW - Water Supply KW - Water Purification -- methods KW - Disinfectants -- analysis KW - Research Design KW - Disinfectants -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69319140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Research+issues+underlying+the+four-lab+study%3A+integrated+disinfection+by-products+mixtures+research.&rft.au=Simmons%2C+Jane+Ellen%3BRichardson%2C+Susan+D%3BTeuschler%2C+Linda+K%3BMiltner%2C+Richard+J%3BSpeth%2C+Thomas+F%3BSchenck%2C+Kathleen+M%3BHunter%2C+E+Sidney%3BRice%2C+Glenn&rft.aulast=Simmons&rft.aufirst=Jane&rft.date=2008-01-01&rft.volume=71&rft.issue=17&rft.spage=1125&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802181906 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-24 N1 - Date created - 2008-07-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15287390802181906 ER - TY - JOUR T1 - The induction of hepatocellular neoplasia by trichloroacetic acid administered in the drinking water of the male B6C3F1 mouse. AN - 69247892; 18569617 AB - The prevalence (percent of animals with a tumor) and multiplicity (number of tumors per animal) of hepatocellular neoplasia in the male B6C3F1 mouse exposed to trichloroacetic acid (TCA) in the drinking water were determined. Male mice were exposed to 0.05, 0.5, and 5 g/L TCA for 60 wk (Study 1), to 4.5 g/L TCA for 104 wk (Study 2) and to 0.05 and 0.5 g/L TCA for 104 wk (Study 3). Time-weighted mean daily doses measured for the low, medium, and high dose groups were consistent over the three studies, 6-8, 58-68, and 572-602 mg/kg-d for the 0.05, 0.5, and the 4.5-5 g/L treatment groups, respectively. No significant changes in animal survival were noted across the studies. A significant increase in the prevalence and multiplicity of hepatocellular tumors was found in the 58-68 and 572-602 mg/kg/d TCA dose groups. Nonhepatoproliferative changes (cytoplasmic alterations, inflammation, and necrosis) in mice treated with TCA were mild and dose related. A TCA-induced increase in liver palmitoyl CoA oxidase activity, a marker of peroxisome proliferation, correlated with tumor induction. A linear association was found between peroxisome proliferation and tumor induction. Sporadic increases in the labeling index of nuclei outside of proliferative lesions were observed at carcinogenic doses throughout the studies. Given that there are no compelling data demonstrating genotoxic activity of either TCA or any metabolite, data are consistent with an epigenetic mode of action. The studies provide dose-response data on the development of hepatocellular neoplasia in male mice over a lifetime exposure to TCA. A no-observed-effect-level (NOEL) of 6 mg/kg/d was calculated for neoplastic and nonproliferative liver pathology. JF - Journal of toxicology and environmental health. Part A AU - DeAngelo, Anthony B AU - Daniel, F Bernard AU - Wong, Diana M AU - George, Michael H AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina 27709, USA. deangelo.anthony@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1056 EP - 1068 VL - 71 IS - 16 SN - 1528-7394, 1528-7394 KW - Caustics KW - 0 KW - Trichloroacetic Acid KW - 5V2JDO056X KW - Oxidoreductases KW - EC 1.- KW - L-Lactate Dehydrogenase KW - EC 1.1.1.27 KW - palmitoyl CoA oxidase KW - EC 1.3.3.- KW - Index Medicus KW - Severity of Illness Index KW - Administration, Oral KW - Animals KW - Regression Analysis KW - Kidney -- pathology KW - Dose-Response Relationship, Drug KW - Kidney -- drug effects KW - Spleen -- pathology KW - Mice KW - Body Weight -- drug effects KW - L-Lactate Dehydrogenase -- blood KW - Spleen -- drug effects KW - Male KW - Organ Size -- drug effects KW - Liver Neoplasms, Experimental -- classification KW - Caustics -- administration & dosage KW - Liver Neoplasms, Experimental -- pathology KW - Trichloroacetic Acid -- toxicity KW - Liver Neoplasms, Experimental -- metabolism KW - Trichloroacetic Acid -- administration & dosage KW - Caustics -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69247892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=The+induction+of+hepatocellular+neoplasia+by+trichloroacetic+acid+administered+in+the+drinking+water+of+the+male+B6C3F1+mouse.&rft.au=DeAngelo%2C+Anthony+B%3BDaniel%2C+F+Bernard%3BWong%2C+Diana+M%3BGeorge%2C+Michael+H&rft.aulast=DeAngelo&rft.aufirst=Anthony&rft.date=2008-01-01&rft.volume=71&rft.issue=16&rft.spage=1056&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802111952 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-07-10 N1 - Date created - 2008-06-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15287390802111952 ER - TY - CONF T1 - Causes, Prevention, and Mitigation Workgroup report. AN - 69199026; 18461770 JF - Advances in experimental medicine and biology AU - Perovich, Gina AU - Dortch, Quay AU - Goodrich, James AU - Berger, Paul S AU - Brooks, Justin AU - Evens, Terence J AU - Gobler, Christopher J AU - Graham, Jennifer AU - Hyde, James AU - Karner, Dawn AU - O'Shea, Dennis AU - Paul, Valerie AU - Paerl, Hans AU - Piehler, Michael AU - Rosen, Barry H AU - Santelmann, Mary AU - Tester, Pat AU - Westrick, Judy Y1 - 2008 PY - 2008 DA - 2008 SP - 185 EP - 215 VL - 619 KW - Bacterial Toxins KW - 0 KW - Marine Toxins KW - Microcystins KW - cyanobacterial toxin KW - Index Medicus KW - Greenhouse Effect KW - Food Chain KW - Fresh Water -- microbiology KW - Humans KW - Microcystins -- toxicity KW - Research Design KW - Models, Biological KW - Microcystins -- analysis KW - Water Supply -- economics KW - Ecosystem KW - Marine Toxins -- analysis KW - Water Supply -- analysis KW - Public Health KW - Bacterial Toxins -- analysis KW - Environmental Monitoring -- economics KW - Seawater -- microbiology KW - Bacterial Toxins -- toxicity KW - Environmental Monitoring -- methods KW - Marine Toxins -- toxicity KW - Cyanobacteria -- pathogenicity KW - Cyanobacteria -- isolation & purification KW - Eutrophication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69199026?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Advances+in+experimental+medicine+and+biology&rft.atitle=Causes%2C+Prevention%2C+and+Mitigation+Workgroup+report.&rft.au=Perovich%2C+Gina%3BDortch%2C+Quay%3BGoodrich%2C+James%3BBerger%2C+Paul+S%3BBrooks%2C+Justin%3BEvens%2C+Terence+J%3BGobler%2C+Christopher+J%3BGraham%2C+Jennifer%3BHyde%2C+James%3BKarner%2C+Dawn%3BO%27Shea%2C+Dennis%3BPaul%2C+Valerie%3BPaerl%2C+Hans%3BPiehler%2C+Michael%3BRosen%2C+Barry+H%3BSantelmann%2C+Mary%3BTester%2C+Pat%3BWestrick%2C+Judy&rft.aulast=Perovich&rft.aufirst=Gina&rft.date=2008-01-01&rft.volume=619&rft.issue=&rft.spage=185&rft.isbn=&rft.btitle=&rft.title=Advances+in+experimental+medicine+and+biology&rft.issn=00652598&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-18 N1 - Date created - 2008-05-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CONF T1 - Occurrence of Cyanobacterial Harmful Algal Blooms Workgroup report. AN - 69198990; 18461765 JF - Advances in experimental medicine and biology AU - Sinclair, James L AU - Hall, Sherwood AU - Berkman, Julie A Hambrook AU - Boyer, Greg AU - Burkholder, JoAnn AU - Burns, John AU - Carmichael, Wayne AU - DuFour, Al AU - Frazier, William AU - Morton, Steve L AU - O'Brien, Eric AU - Walker, Steven Y1 - 2008 PY - 2008 DA - 2008 SP - 45 EP - 103 VL - 619 KW - Bacterial Toxins KW - 0 KW - Marine Toxins KW - Microcystins KW - cyanobacterial toxin KW - Index Medicus KW - United States KW - Ecosystem KW - Public Health KW - Fresh Water -- microbiology KW - Humans KW - Microcystins -- toxicity KW - Bacterial Toxins -- chemistry KW - Seawater -- microbiology KW - Bacterial Toxins -- toxicity KW - Microcystins -- chemistry KW - Marine Toxins -- toxicity KW - Marine Toxins -- chemistry KW - Cyanobacteria -- pathogenicity KW - Cyanobacteria -- isolation & purification KW - Eutrophication KW - Cyanobacteria -- classification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69198990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Advances+in+experimental+medicine+and+biology&rft.atitle=Occurrence+of+Cyanobacterial+Harmful+Algal+Blooms+Workgroup+report.&rft.au=Sinclair%2C+James+L%3BHall%2C+Sherwood%3BBerkman%2C+Julie+A+Hambrook%3BBoyer%2C+Greg%3BBurkholder%2C+JoAnn%3BBurns%2C+John%3BCarmichael%2C+Wayne%3BDuFour%2C+Al%3BFrazier%2C+William%3BMorton%2C+Steve+L%3BO%27Brien%2C+Eric%3BWalker%2C+Steven&rft.aulast=Sinclair&rft.aufirst=James&rft.date=2008-01-01&rft.volume=619&rft.issue=&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Advances+in+experimental+medicine+and+biology&rft.issn=00652598&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-18 N1 - Date created - 2008-05-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CONF T1 - Risk Assessment Workgroup report. AN - 69196343; 18461791 AB - The Risk Assessment Work Group focused on six charge questions related to CHABS, cyanobacteria and their toxins. The charge questions covered the following topics: Research needed to reduce uncertainty in establishing health based guidelines. Research that minimize the cost and maximize the benefits of various regulatory approaches. Exposure pathways for receptors of concern. Data available to support the derivation of health-based guideline values for harmful cyanobacterial algal blooms. Ecological services that guidelines or regulations should protect? A framework for making risk management determinations that incorporates consideration of the characteristics of CHABs, the risk for human health, ecosystem viability, and the costs and benefits of CHABs detection and management? The Work Group concluded that there is a considerable amount of human case-study data and information from animal studies to demonstrate that cyanobacterial toxins pose a hazard to humans, domestic animals, wildlife, and the ecosystem. However, the data on dose-response are limited and confounded by a lack of sufficient pure toxin to conduct most of the toxicological studies that will be needed in order to answer remaining questions on risk, and to provide the data for quantitative dose-response analysis. The Work Group recommended that research on purification or synthesis of pure toxin must be accomplished before the large scale studies to establish dose-response relationships will be possible. As the necessary-pure toxins become available, the Work Group recommended that studies be prioritized by the impact that they will have on reducing the uncertainty in the risk assessment in order to minimize the research costs and maximize the risk assessment benefits. Use of quantitative structure activity relationships (QSAR) and toxicity equivalency factor studies are also recommended as approaches for filling dose-response data gaps. The Work Group recognized that CHABs rarely introduce single toxins into the water supply. Under CHAB conditions, affected water is likely to contain a variety of toxins in varying concentrations that may change over the duration of the bloom. Accordingly, research on cyanotoxin interactions is needed, along with the development of risk assessment approaches for CHAB mixtures. The development of simple, accurate analytical methods that can be utilized by most analytical laboratories or used in the field was recognized as a major data need for establishing exposure potential and monitoring bloom conditions. Most currently available methods are time-consuming and/or costly. Human exposure to cyanobacterial toxins can occur through ingestion of contaminated drinking water, plus dermal contact and/or inhalation of aerosols while bathing and showering in tap water. Treatment can reduce the concentrations of both the toxins and the bacteria in the treated water but there is still much to be learned about the effectiveness of most treatment technologies on cyanobacteria and toxin removal. Human exposure to cyanobacteria and their toxins also occurs through incidental ingestion, dermal contact, and inhalation of aerosols during recreational use of surface waters, ingestion of contaminated fish and other foods of aquatic origin, and/or BGAS supplements. Establishing intakes and duration parameters for these exposure scenarios will facilitate the application of risk assessment approaches to these situations. JF - Advances in experimental medicine and biology AU - Donohue, Joyce AU - Orme-Zavaleta, Jennifer AU - Burch, Michael AU - Dietrich, Daniel AU - Hawkins, Belinda AU - Lloyd, Tony AU - Munns, Wayne AU - Steevens, Jeffery AU - Steffensen, Dennis AU - Stone, Dave AU - Tango, Peter Y1 - 2008 PY - 2008 DA - 2008 SP - 759 EP - 829 VL - 619 KW - Bacterial Toxins KW - 0 KW - Marine Toxins KW - Microcystins KW - cyanobacterial toxin KW - Index Medicus KW - United States KW - Animals KW - United States Environmental Protection Agency KW - Environmental Health KW - Humans KW - Research Design KW - United Kingdom KW - Risk Assessment KW - Ecosystem KW - World Health Organization KW - Water Supply -- analysis KW - Water Supply -- standards KW - Risk Management KW - Australia KW - Water Supply -- legislation & jurisprudence KW - New Zealand KW - Models, Theoretical KW - Marine Toxins -- analysis KW - Cyanobacteria -- pathogenicity KW - Bacterial Toxins -- analysis KW - Eutrophication KW - Marine Toxins -- administration & dosage KW - Microcystins -- toxicity KW - Microcystins -- administration & dosage KW - Bacterial Toxins -- toxicity KW - Bacterial Toxins -- administration & dosage KW - Microcystins -- analysis KW - Marine Toxins -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69196343?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Advances+in+experimental+medicine+and+biology&rft.atitle=Risk+Assessment+Workgroup+report.&rft.au=Donohue%2C+Joyce%3BOrme-Zavaleta%2C+Jennifer%3BBurch%2C+Michael%3BDietrich%2C+Daniel%3BHawkins%2C+Belinda%3BLloyd%2C+Tony%3BMunns%2C+Wayne%3BSteevens%2C+Jeffery%3BSteffensen%2C+Dennis%3BStone%2C+Dave%3BTango%2C+Peter&rft.aulast=Donohue&rft.aufirst=Joyce&rft.date=2008-01-01&rft.volume=619&rft.issue=&rft.spage=759&rft.isbn=&rft.btitle=&rft.title=Advances+in+experimental+medicine+and+biology&rft.issn=00652598&rft_id=info:doi/10.1007%2F978-0-387-75865-7_35 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-18 N1 - Date created - 2008-05-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/978-0-387-75865-7_35 ER - TY - CONF T1 - Analytical Methods Workgroup report. AN - 69196210; 18461779 JF - Advances in experimental medicine and biology AU - de la Cruz, Armah A AU - Rublee, Parke AU - Hungerford, James M AU - Zimba, Paul V AU - Wilhelm, Steven W AU - Meriluoto, Jussi A O AU - Echols, Kathy AU - Meyer, Michael T AU - Stelma, Gerard AU - Mandeville, Rosemonde AU - Lawton, Linda AU - Sivonen, Kaarina AU - Furey, Ambrose Y1 - 2008 PY - 2008 DA - 2008 SP - 469 EP - 481 VL - 619 KW - Bacterial Toxins KW - 0 KW - Marine Toxins KW - Microcystins KW - cyanobacterial toxin KW - Index Medicus KW - United States KW - Public Health KW - Fresh Water -- analysis KW - Fresh Water -- microbiology KW - Humans KW - Reference Standards KW - Environmental Monitoring -- standards KW - Environmental Monitoring -- methods KW - Risk Assessment KW - Environmental Monitoring -- instrumentation KW - Bacterial Toxins -- standards KW - Marine Toxins -- analysis KW - Cyanobacteria -- pathogenicity KW - Cyanobacteria -- isolation & purification KW - Marine Toxins -- standards KW - Bacterial Toxins -- analysis KW - Eutrophication KW - Microcystins -- toxicity KW - Microcystins -- standards KW - Bacterial Toxins -- toxicity KW - Microcystins -- analysis KW - Marine Toxins -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69196210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Advances+in+experimental+medicine+and+biology&rft.atitle=Analytical+Methods+Workgroup+report.&rft.au=de+la+Cruz%2C+Armah+A%3BRublee%2C+Parke%3BHungerford%2C+James+M%3BZimba%2C+Paul+V%3BWilhelm%2C+Steven+W%3BMeriluoto%2C+Jussi+A+O%3BEchols%2C+Kathy%3BMeyer%2C+Michael+T%3BStelma%2C+Gerard%3BMandeville%2C+Rosemonde%3BLawton%2C+Linda%3BSivonen%2C+Kaarina%3BFurey%2C+Ambrose&rft.aulast=de+la+Cruz&rft.aufirst=Armah&rft.date=2008-01-01&rft.volume=619&rft.issue=&rft.spage=469&rft.isbn=&rft.btitle=&rft.title=Advances+in+experimental+medicine+and+biology&rft.issn=00652598&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-18 N1 - Date created - 2008-05-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CONF T1 - Cyanotoxins Workgroup report. AN - 69194900; 18461775 JF - Advances in experimental medicine and biology AU - Pegram, Rex A AU - Nichols, Tonya AU - Etheridge, Stacey AU - Humpage, Andrew AU - LeBlanc, Susan AU - Love, Adam AU - Neilan, Brett AU - Pflugmacher, Stephan AU - Runnegar, Maria AU - Thacker, Robert Y1 - 2008 PY - 2008 DA - 2008 SP - 317 EP - 381 VL - 619 KW - Bacterial Toxins KW - 0 KW - Marine Toxins KW - Microcystins KW - cyanobacterial toxin KW - cylindrospermopsin KW - 2JIZ556BA3 KW - Uracil KW - 56HH86ZVCT KW - Index Medicus KW - Animals KW - Uracil -- analogs & derivatives KW - Fresh Water -- microbiology KW - Humans KW - Reference Standards KW - Environmental Monitoring -- standards KW - Research Design KW - Pharmacokinetics KW - Risk Assessment KW - Public Health KW - Ecotoxicology KW - Fresh Water -- analysis KW - Polymerase Chain Reaction -- methods KW - Uracil -- toxicity KW - Uracil -- analysis KW - Environmental Monitoring -- methods KW - Cyanobacteria -- pathogenicity KW - Marine Toxins -- standards KW - Eutrophication KW - Microcystins -- pharmacokinetics KW - Microcystins -- toxicity KW - Microcystins -- standards KW - Microcystins -- analysis KW - Marine Toxins -- pharmacokinetics KW - Bacterial Toxins -- standards KW - Marine Toxins -- analysis KW - Cyanobacteria -- isolation & purification KW - Bacterial Toxins -- analysis KW - Bacterial Toxins -- pharmacokinetics KW - Bacterial Toxins -- toxicity KW - Cyanobacteria -- genetics KW - Marine Toxins -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69194900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Advances+in+experimental+medicine+and+biology&rft.atitle=Cyanotoxins+Workgroup+report.&rft.au=Pegram%2C+Rex+A%3BNichols%2C+Tonya%3BEtheridge%2C+Stacey%3BHumpage%2C+Andrew%3BLeBlanc%2C+Susan%3BLove%2C+Adam%3BNeilan%2C+Brett%3BPflugmacher%2C+Stephan%3BRunnegar%2C+Maria%3BThacker%2C+Robert&rft.aulast=Pegram&rft.aufirst=Rex&rft.date=2008-01-01&rft.volume=619&rft.issue=&rft.spage=317&rft.isbn=&rft.btitle=&rft.title=Advances+in+experimental+medicine+and+biology&rft.issn=00652598&rft_id=info:doi/10.1007%2F978-0-387-75865-7_15 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-18 N1 - Date created - 2008-05-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/978-0-387-75865-7_15 ER - TY - JOUR T1 - Collaboration between monitoring authorities, regulatory authorities and test facilities on GLP principles provides confidence in data quality with an emphasis on sound science. GLP: an example of a focused effort that paid off. AN - 66710287; 19351996 AB - The herbicide atrazine has been the subject of numerous studies investigating its potential effects on amphibians. The United States Environmental Protection Agency (EPA) required the atrazine registrant to conduct a tiered study approach. Tier I of the studies involved laboratory studies to determine whether atrazine affects amphibian gonadal development. Several good laboratory practice (GLP) inspections were conducted during the Tier 1 atrazine amphibian study entitled "Response of larval Xenopus laevis to atrazine exposure: assessment of metamorphosis and gonadal morphology". These inspections were conducted on each of the in-life (Phase 1) test facilities (TF), i.e., Wildlife International (WLI) Ltd. (Easton, Md, USA) and the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB) (Berlin, Germany). All of the inspections were conducted in conjunction with the EPA GLP monitoring authority (MA), the Office of Enforcement, Compliance and Assurance (OECA) as well as auditors from the regulatory authority (RA) Office of Pesticide Programs (OPP). The inspection of the German facility also included representatives of the German equivalent of OECA. In Phase II of the Tier 1 study, tissue samples collected by both IGB and WLI during Phase I were prepared for histology and reviewed by a veterinary pathologist at the Experimental Pathology Laboratory (Vienna, Virginia, USA). The cooperation between the MA, RA and the TF allowed OPP to ensure the GLP principles were being followed as well as allowing everyone involved to bring up some higher level science issues associated with the study execution. JF - Annali dell'Istituto superiore di sanita AU - Grim, Betsy AU - Steeger, Thomas AD - United States Environmental Protection Agency, Office of Pesticide Programs, 1200 Pennsylvania Avenue, NW, Washington, DC 20460, USA. Grim.betsy@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 359 EP - 362 VL - 44 IS - 4 SN - 0021-2571, 0021-2571 KW - Herbicides KW - 0 KW - Atrazine KW - QJA9M5H4IM KW - Index Medicus KW - United States KW - Animals KW - Amphibians KW - Germany KW - Clinical Laboratory Techniques -- standards KW - Social Control, Formal KW - Research -- standards KW - Research Design -- standards KW - Interdisciplinary Communication KW - Herbicides -- toxicity KW - Atrazine -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66710287?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annali+dell%27Istituto+superiore+di+sanita&rft.atitle=Collaboration+between+monitoring+authorities%2C+regulatory+authorities+and+test+facilities+on+GLP+principles+provides+confidence+in+data+quality+with+an+emphasis+on+sound+science.+GLP%3A+an+example+of+a+focused+effort+that+paid+off.&rft.au=Grim%2C+Betsy%3BSteeger%2C+Thomas&rft.aulast=Grim&rft.aufirst=Betsy&rft.date=2008-01-01&rft.volume=44&rft.issue=4&rft.spage=359&rft.isbn=&rft.btitle=&rft.title=Annali+dell%27Istituto+superiore+di+sanita&rft.issn=00212571&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-06-22 N1 - Date created - 2009-04-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Assessment of toxicity potential of metallic elements in discarded electronics: a case study of mobile phones in China. AN - 66679331; 19202883 AB - The electronic waste (e-waste) is increasingly flooding Asia, especially China. E-waste could precipitate a growing volume of toxic input to the local environment if it was not handed properly. This makes the evaluation of environmental impact from electronics an essentially important task for the life cycle assessment (LCA) and the end-of-life management of electronic products. This study presented a quantitative investigation on the environmental performance of typical electronics. Two types of disposed mobile phones (MPs), as a representative of consumer electronics, were evaluated in terms of toxicity potential indicator (TPI) with an assumption of worst-case scenario. It is found that the composition and the percentages of constituents in MPs are similar. More than 20 metallic elements make up 35 wt.%-40 wt.% of the total weight, of which 12 elements are identified to be highly hazardous and 12 are less harmful. With the TPI technique, the environmental performance of Pb is attributed to be 20.8 mg(-1). The total TPIs of metallic elements in the old and new type MP is 255,403 and 127,639 units, respectively, which is equivalent to the effect of releasing 6.14 and 12.28 g Pb into the environment. The average TPI of the old and new type MP is 4.1 and 4.5 mg(-1), respectively, which suggests a similar eco-efficiency per unit mass. The new model of MP is more eco-effective than the old one, which is not due to a reduction in the type of hazardous elements, but rather due to a significant miniaturization of the package with less weight. A single MP can have a considerable toxicity to the environment as referred to Pb, which suggests a major concern for the environmental impact of the total e-waste with a huge quantity and a heavy mass in China. JF - Journal of environmental sciences (China) AU - Wu, B Y AU - Chan, Y C AU - Middendorf, A AU - Gu, X AU - Zhong, H W AD - EPA Centre, City University of Hong Kong, 83#, Tat Chee Avenue, Kowloon, Hong Kong 852, China. Y1 - 2008 PY - 2008 DA - 2008 SP - 1403 EP - 1408 VL - 20 IS - 11 SN - 1001-0742, 1001-0742 KW - Industrial Waste KW - 0 KW - Metals KW - Index Medicus KW - China KW - Electronics KW - Cell Phones KW - Metals -- analysis KW - Metals -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66679331?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+sciences+%28China%29&rft.atitle=Assessment+of+toxicity+potential+of+metallic+elements+in+discarded+electronics%3A+a+case+study+of+mobile+phones+in+China.&rft.au=Wu%2C+B+Y%3BChan%2C+Y+C%3BMiddendorf%2C+A%3BGu%2C+X%3BZhong%2C+H+W&rft.aulast=Wu&rft.aufirst=B&rft.date=2008-01-01&rft.volume=20&rft.issue=11&rft.spage=1403&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+sciences+%28China%29&rft.issn=10010742&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-03-19 N1 - Date created - 2009-02-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The U.S. Environmental Protection Agency's Particulate Matter Supersites Program: an integrated synthesis of scientific findings and policy- and health-relevant insights. AN - 66675255; 19202992 JF - Journal of the Air & Waste Management Association (1995) AU - Solomon, Paul A AU - Hopke, Philip K AD - National Exposure Research Laboratory, Office of Research and Development at EPA, Las Vegas, NV, USA. solomon.paul@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - S1 EP - S2 VL - 58 IS - 13 Suppl SN - 1096-2247, 1096-2247 KW - Particulate Matter KW - 0 KW - Index Medicus KW - United States KW - United States Environmental Protection Agency -- legislation & jurisprudence KW - Public Health KW - Air Pollution -- prevention & control KW - Particulate Matter -- standards KW - Air Pollution -- legislation & jurisprudence KW - Public Policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/66675255?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=The+U.S.+Environmental+Protection+Agency%27s+Particulate+Matter+Supersites+Program%3A+an+integrated+synthesis+of+scientific+findings+and+policy-+and+health-relevant+insights.&rft.au=Solomon%2C+Paul+A%3BHopke%2C+Philip+K&rft.aulast=Solomon&rft.aufirst=Paul&rft.date=2008-01-01&rft.volume=58&rft.issue=13+Suppl&rft.spage=S1&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-03-05 N1 - Date created - 2009-02-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - An Oceans Manifesto: The Present Global Crisis AN - 60491495; 201005459 AB - Ever-increasing challenges test the health of the oceans and amplify the global impact of their ecological deterioration. Though government policy, economics, and multilateral engagement have begun to address environmental concerns, the creation of a Global Environment Organization, in combination with grassroots activism, would provide a viable framework for moving forward. (View). Adapted from the source document. JF - The Fletcher Forum of World Affairs AU - Sielen, Alan B AD - EPA, Washington, DC Y1 - 2008/01// PY - 2008 DA - January 2008 PB - The Fletcher School, Tufts University, Medford MA VL - 32 IS - 1 SN - 1046-1868, 1046-1868 KW - Multilateralism KW - International Cooperation KW - Oceans KW - Environmental Degradation KW - Governance KW - article KW - 9063: international relations; international relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60491495?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Fletcher+Forum+of+World+Affairs&rft.atitle=An+Oceans+Manifesto%3A+The+Present+Global+Crisis&rft.au=Sielen%2C+Alan+B&rft.aulast=Sielen&rft.aufirst=Alan&rft.date=2008-01-01&rft.volume=32&rft.issue=1&rft.spage=&rft.isbn=&rft.btitle=&rft.title=The+Fletcher+Forum+of+World+Affairs&rft.issn=10461868&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2010-02-03 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Oceans; Environmental Degradation; International Cooperation; Governance; Multilateralism ER - TY - JOUR T1 - Expert input on science and technology in policy development AN - 58792987; 2008-206681 AB - Science and technology are crucial to Africa's development, but the majority of African Parliaments lack many resources to provide their Members with scientific and technological information. Responding to a request from several African parliamentary delegations, including some organized by the Commonwealth Parliamentary Association, the Parliamentary Office of Science and Technology in the United Kingdom Parliament has started a programme to help African Parliaments build capacity in this critical area. Adapted from the source document. JF - The Parliamentarian AU - Nath, Chandrika AD - Parliamentary Office of Science and Technology of the United Kingdom Parliament Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 49 EP - 50 PB - Commonwealth Parliamentary Association, London UK VL - 89 IS - 1 SN - 0031-2282, 0031-2282 KW - Science and technology policy - Technology and technology policy KW - Science and technology policy - Science and science policy and research KW - Parliament KW - Africa KW - Science KW - United Kingdom KW - Technology KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58792987?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Parliamentarian&rft.atitle=Expert+input+on+science+and+technology+in+policy+development&rft.au=Nath%2C+Chandrika&rft.aulast=Nath&rft.aufirst=Chandrika&rft.date=2008-01-01&rft.volume=89&rft.issue=1&rft.spage=49&rft.isbn=&rft.btitle=&rft.title=The+Parliamentarian&rft.issn=00312282&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2008-11-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Technology; Parliament; Science; Africa; United Kingdom ER - TY - JOUR T1 - Viruses in ground water AN - 51238537; 2008-073909 JF - NATO Science for Peace and Security Series C: Environmental Security AU - Berger, Philip Y1 - 2008 PY - 2008 DA - 2008 SP - 131 EP - 149 PB - Springer, Dordrecht VL - Unnumbered SN - 1871-4668, 1871-4668 KW - United States KW - fractured materials KW - water quality KW - regulations KW - karst hydrology KW - karst KW - ground water KW - pump tests KW - Oregon KW - coarse-grained materials KW - coliform bacteria KW - Jackson County North Carolina KW - Henderson County Illinois KW - bedrock KW - concentration KW - water supply KW - Illinois KW - matrix KW - Michigan Upper Peninsula KW - pollution KW - porous materials KW - aquifers KW - Umatilla County Oregon KW - case studies KW - Chippewa County Michigan KW - Juniata County Pennsylvania KW - Chester County Pennsylvania KW - North Carolina KW - bacteria KW - viruses KW - Michigan KW - Pennsylvania KW - water wells KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51238537?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=NATO+Science+for+Peace+and+Security+Series+C%3A+Environmental+Security&rft.atitle=Viruses+in+ground+water&rft.au=Berger%2C+Philip&rft.aulast=Berger&rft.aufirst=Philip&rft.date=2008-01-01&rft.volume=Unnumbered&rft.issue=&rft.spage=131&rft.isbn=1402068003&rft.btitle=&rft.title=NATO+Science+for+Peace+and+Security+Series+C%3A+Environmental+Security&rft.issn=18714668&rft_id=info:doi/ L2 - http://www.springerlink.com/content/119861 LA - English DB - GeoRef N1 - Conference title - NATO advanced research workshop in Dangerous pollutants (xenobiotics) in urban water cycle N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 58 N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - aquifers; bacteria; bedrock; case studies; Chester County Pennsylvania; Chippewa County Michigan; coarse-grained materials; coliform bacteria; concentration; fractured materials; ground water; Henderson County Illinois; Illinois; Jackson County North Carolina; Juniata County Pennsylvania; karst; karst hydrology; matrix; Michigan; Michigan Upper Peninsula; North Carolina; Oregon; Pennsylvania; pollution; porous materials; pump tests; regulations; Umatilla County Oregon; United States; viruses; water quality; water supply; water wells ER - TY - JOUR T1 - The San Pedro River; a case study for examining past landscape change and forecasting hydrological and biological response to urban growth and land-use change AN - 51014071; 2008-088328 JF - U. S. Geological Survey Circular AU - Kepner, William G AU - Boykin, Kenneth G AU - Semmens, Darius J AU - Goodrich, David C AU - Watts, Christopher J AU - Guertin, D Phillip Y1 - 2008 PY - 2008 DA - 2008 SP - 39 EP - 40 PB - U. S. Geological Survey, Reston, VA SN - 1067-084X, 1067-084X KW - United States KW - Sonora Mexico KW - hydrology KW - spatial data KW - landform evolution KW - San Pedro River basin KW - urbanization KW - models KW - case studies KW - habitat KW - Mexico KW - geographic information systems KW - Arizona KW - fluvial features KW - drainage basins KW - information systems KW - ecology KW - landscapes KW - USGS KW - remote sensing KW - 23:Geomorphology KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51014071?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=U.+S.+Geological+Survey+Circular&rft.atitle=The+San+Pedro+River%3B+a+case+study+for+examining+past+landscape+change+and+forecasting+hydrological+and+biological+response+to+urban+growth+and+land-use+change&rft.au=Kepner%2C+William+G%3BBoykin%2C+Kenneth+G%3BSemmens%2C+Darius+J%3BGoodrich%2C+David+C%3BWatts%2C+Christopher+J%3BGuertin%2C+D+Phillip&rft.aulast=Kepner&rft.aufirst=William&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=39&rft.isbn=&rft.btitle=&rft.title=U.+S.+Geological+Survey+Circular&rft.issn=1067084X&rft_id=info:doi/ L2 - http://pubs.usgs.gov/circ/1322/ LA - English DB - GeoRef N1 - Conference title - Workshop on Facing tomorrow's challenges along the U. S.-Mexico border N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - VA N1 - Document feature - sketch maps N1 - SuppNotes - Accessed on April 25, 2008 N1 - Last updated - 2014-03-14 N1 - SubjectsTermNotLitGenreText - Arizona; case studies; drainage basins; ecology; fluvial features; geographic information systems; habitat; hydrology; information systems; landform evolution; landscapes; Mexico; models; remote sensing; San Pedro River basin; Sonora Mexico; spatial data; United States; urbanization; USGS ER - TY - JOUR T1 - Automated Geospatial Watershed Assessment (AGWA); a GIS-based hydrologic modeling tool for watershed assessment and analysis AN - 51011382; 2008-088333 JF - U. S. Geological Survey Circular AU - Guertin, D Phillip AU - Goodrich, David C AU - Kepner, William G AU - Semmens, Darius J AU - Hernandez, Mariano AU - Burns, Shea AU - Cate, Averill AU - Levick, Lainie AU - Miller, Scott N Y1 - 2008 PY - 2008 DA - 2008 SP - 49 EP - 50 PB - U. S. Geological Survey, Reston, VA SN - 1067-084X, 1067-084X KW - soils KW - hydrology KW - land cover KW - spatial data KW - data processing KW - watersheds KW - mapping KW - digital terrain models KW - Automated Geospatial Watershed Assessment KW - computer programs KW - geographic information systems KW - information systems KW - USGS KW - land use KW - digitization KW - 21:Hydrogeology KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51011382?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=U.+S.+Geological+Survey+Circular&rft.atitle=Automated+Geospatial+Watershed+Assessment+%28AGWA%29%3B+a+GIS-based+hydrologic+modeling+tool+for+watershed+assessment+and+analysis&rft.au=Guertin%2C+D+Phillip%3BGoodrich%2C+David+C%3BKepner%2C+William+G%3BSemmens%2C+Darius+J%3BHernandez%2C+Mariano%3BBurns%2C+Shea%3BCate%2C+Averill%3BLevick%2C+Lainie%3BMiller%2C+Scott+N&rft.aulast=Guertin&rft.aufirst=D&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=49&rft.isbn=&rft.btitle=&rft.title=U.+S.+Geological+Survey+Circular&rft.issn=1067084X&rft_id=info:doi/ L2 - http://pubs.usgs.gov/circ/1322/ LA - English DB - GeoRef N1 - Conference title - Workshop on Facing tomorrow's challenges along the U. S.-Mexico border N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 6 N1 - PubXState - VA N1 - Document feature - illus. N1 - SuppNotes - Accessed on April 25, 2008 N1 - Last updated - 2014-03-14 N1 - SubjectsTermNotLitGenreText - Automated Geospatial Watershed Assessment; computer programs; data processing; digital terrain models; digitization; geographic information systems; hydrology; information systems; land cover; land use; mapping; soils; spatial data; USGS; watersheds ER - TY - JOUR T1 - Contemporary digital land-cover mapping for the American Southwest; the Southwest Regional Gap Analysis Project AN - 51010922; 2008-088329 JF - U. S. Geological Survey Circular AU - Lowry, John AU - Kepner, William G AU - Boykin, Kenneth G AU - Thomas, Kathryn A AU - Schrupp, Donald L AU - Comer, Pat Y1 - 2008 PY - 2008 DA - 2008 SP - 41 EP - 42 PB - U. S. Geological Survey, Reston, VA SN - 1067-084X, 1067-084X KW - United States KW - land cover KW - biodiversity KW - cartography KW - mapping KW - landforms KW - vegetation KW - Southwestern U.S. KW - satellite methods KW - geographic information systems KW - digital cartography KW - Gap Analysis Program KW - information systems KW - ecology KW - landscapes KW - USGS KW - land use KW - remote sensing KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51010922?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=U.+S.+Geological+Survey+Circular&rft.atitle=Contemporary+digital+land-cover+mapping+for+the+American+Southwest%3B+the+Southwest+Regional+Gap+Analysis+Project&rft.au=Lowry%2C+John%3BKepner%2C+William+G%3BBoykin%2C+Kenneth+G%3BThomas%2C+Kathryn+A%3BSchrupp%2C+Donald+L%3BComer%2C+Pat&rft.aulast=Lowry&rft.aufirst=John&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=U.+S.+Geological+Survey+Circular&rft.issn=1067084X&rft_id=info:doi/ L2 - http://pubs.usgs.gov/circ/1322/ LA - English DB - GeoRef N1 - Conference title - Workshop on Facing tomorrow's challenges along the U. S.-Mexico border N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - VA N1 - Document feature - sketch map N1 - SuppNotes - Accessed on April 25, 2008 N1 - Last updated - 2014-03-14 N1 - SubjectsTermNotLitGenreText - biodiversity; cartography; digital cartography; ecology; Gap Analysis Program; geographic information systems; information systems; land cover; land use; landforms; landscapes; mapping; remote sensing; satellite methods; Southwestern U.S.; United States; USGS; vegetation ER - TY - JOUR T1 - Real-time and delayed analysis of tree and shrub cores as indicators of subsurface volatile organic compound contamination, Durham Meadows Superfund Site, Durham, Connecticut, August 29, 2006 AN - 51005899; 2008-093339 AB - This study examined volatile organic compound concentrations in cores from trees and shrubs for use as indicators of vadose-zone contamination or potential vapor intrusion by volatile organic compounds into buildings at the Durham Meadows Superfund Site, Durham, Connecticut. The study used both (1) real-time tree- and shrub-core analysis, which involved field heating the core samples for 5 to 10 minutes prior to field analysis, and (2) delayed analysis, which involved allowing the gases in the cores to equilibrate with the headspace gas in the sample vials unheated for 1 to 2 days prior to analysis. General correspondence was found between the two approaches, indicating that preheating and field analysis of vegetation cores is a viable approach to real-time monitoring of subsurface volatile organic compounds. In most cases, volatile organic compounds in cores from trees and shrubs at the Merriam Manufacturing Company property showed a general correspondence to the distribution of volatile organic compounds detected in a soil-gas survey, despite the fact that most of the soil-gas survey data in close proximity to the relevant trees were collected about 3 years prior to the tree-core collection. Most of the trees cored at the Durham Meadows Superfund Site, outside of the Merriam Manufacturing Company property, contained no volatile organic compounds and were in areas where indoor air sampling and soil-gas sampling showed little or no volatile organic compound concentrations. An exception was tree DM11, which contained barely detectable concentrations of trichloroethene near a house where previous investigations found low concentrations of trichloroethene (0.13 to 1.2 parts per billion by volume) in indoor air and 7.7 micrograms per liter of trichloroethene in the ground water. JF - Scientific Investigations Report AU - Vroblesky, Don A AU - Willey, Richard E AU - Clifford, Scott AU - Murphy, James J Y1 - 2008 PY - 2008 DA - 2008 SP - 12 PB - U. S. Geological Survey, Reston, VA SN - 2328-031X, 2328-031X KW - United States KW - chlorinated hydrocarbons KW - Durham Connecticut KW - unsaturated zone KW - vegetation KW - environmental analysis KW - cores KW - sampling KW - halogenated hydrocarbons KW - USGS KW - Superfund sites KW - pollutants KW - pollution KW - indicators KW - Connecticut KW - volatiles KW - organic compounds KW - soil pollution KW - volatile organic compounds KW - surveys KW - Durham Meadows Superfund Site KW - Middlesex County Connecticut KW - trichloroethylene KW - soil gases KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51005899?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Vroblesky%2C+Don+A%3BWilley%2C+Richard+E%3BClifford%2C+Scott%3BMurphy%2C+James+J&rft.aulast=Vroblesky&rft.aufirst=Don&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Real-time+and+delayed+analysis+of+tree+and+shrub+cores+as+indicators+of+subsurface+volatile+organic+compound+contamination%2C+Durham+Meadows+Superfund+Site%2C+Durham%2C+Connecticut%2C+August+29%2C+2006&rft.title=Real-time+and+delayed+analysis+of+tree+and+shrub+cores+as+indicators+of+subsurface+volatile+organic+compound+contamination%2C+Durham+Meadows+Superfund+Site%2C+Durham%2C+Connecticut%2C+August+29%2C+2006&rft.issn=2328031X&rft_id=info:doi/ L2 - http://www.usgs.pubs LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 17 N1 - PubXState - VA N1 - Document feature - illus. incl. 4 tables, sketch maps N1 - SuppNotes - Accessed on May 28, 2008; Prepared in cooperation with the U.S. Environmental Protection Agency N1 - Last updated - 2014-09-18 N1 - SubjectsTermNotLitGenreText - chlorinated hydrocarbons; Connecticut; cores; Durham Connecticut; Durham Meadows Superfund Site; environmental analysis; halogenated hydrocarbons; indicators; Middlesex County Connecticut; organic compounds; pollutants; pollution; sampling; soil gases; soil pollution; Superfund sites; surveys; trichloroethylene; United States; unsaturated zone; USGS; vegetation; volatile organic compounds; volatiles ER - TY - JOUR T1 - Sedimentation history of Halfway Creek Marsh, Upper Mississippi River National Wildlife and Fish Refuge, Wisconsin, 1846-2006 AN - 51003367; 2008-093337 AB - The history of overbank sedimentation in the vicinity of Halfway Creek Marsh near La Crosse, Wis., was examined during 2005-06 by the U.S. Geological Survey and University of Wisconsin-Madison as part of a broader study of sediment and nutrient loadings to the Upper Mississippi River bottomlands by the U.S. Environmental Protection Agency, U.S. Fish and Wildlife Service, and U.S. Geological Survey. Historical sedimentation patterns and rates were interpreted from field-scale topographic surveys and sediment cores collected from the marsh and upstream flood plains. Historical maps and aerial photographs were used to establish the timing of disturbances and to document changes in channel patterns after Euro-American settlement (post 1846). Episodic overbank sedimentation patterns and rates were linked to watershed agricultural activity, large floods, artificial levee construction, channel alterations, and dam failures over the past 160 years. These forces affected sedimentation on and between levees, the development of alluvial fans and flood-plain splays, and the general pattern of flood-plain sedimentation through the upper and lower marsh. Historical overbank deposits, episodically deposited after about 1860, are as much as 6 feet thick in the upper marsh and as much as 4 feet thick in the lower marsh, representing a total volume of approximately 1.8 million cubic yards. JF - Scientific Investigations Report AU - Fitzpatrick, Faith A AU - Knox, James C AU - Schubauer-Berigan, Joseph P Y1 - 2008 PY - 2008 DA - 2008 SP - 40 PB - U. S. Geological Survey, Reston, VA KW - Upper Mississippi River National Wildlife and Fish Refuge KW - United States KW - hydrology KW - water quality KW - Upper Mississippi Valley KW - sediment transport KW - Mississippi Valley KW - marshes KW - loading KW - floodplains KW - surface water KW - sedimentation KW - watersheds KW - Halfway Creek Marsh KW - nutrients KW - mires KW - sediments KW - fluvial features KW - aerial photography KW - Wisconsin KW - USGS KW - remote sensing KW - 06A:Sedimentary petrology KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51003367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Fitzpatrick%2C+Faith+A%3BKnox%2C+James+C%3BSchubauer-Berigan%2C+Joseph+P&rft.aulast=Fitzpatrick&rft.aufirst=Faith&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Sedimentation+history+of+Halfway+Creek+Marsh%2C+Upper+Mississippi+River+National+Wildlife+and+Fish+Refuge%2C+Wisconsin%2C+1846-2006&rft.title=Sedimentation+history+of+Halfway+Creek+Marsh%2C+Upper+Mississippi+River+National+Wildlife+and+Fish+Refuge%2C+Wisconsin%2C+1846-2006&rft.issn=&rft_id=info:doi/ L2 - http://pubs.usgs.gov/sir/2007/5209/ http://pubs.usgs.gov/sir/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 37 N1 - PubXState - VA N1 - Document feature - illus. incl. sects., 2 tables, sketch maps N1 - SuppNotes - Accessed on May 28, 2008; Prepared in cooperation with U.S. Environmental Protection Agency N1 - Last updated - 2012-06-07 N1 - CODEN - #06439 N1 - SubjectsTermNotLitGenreText - aerial photography; floodplains; fluvial features; Halfway Creek Marsh; hydrology; loading; marshes; mires; Mississippi Valley; nutrients; remote sensing; sediment transport; sedimentation; sediments; surface water; United States; Upper Mississippi River National Wildlife and Fish Refuge; Upper Mississippi Valley; USGS; water quality; watersheds; Wisconsin ER - TY - JOUR T1 - Environmental chemistry, ecotoxocity, and fate of lambda-cyhalothrin AN - 50619180; 2008-111676 JF - Reviews of Environmental Contamination and Toxicology AU - He, Li-Ming AU - Troiano, John AU - Wang, Albert AU - Goh, Kean Y1 - 2008 PY - 2008 DA - 2008 SP - 71 EP - 91 PB - Springer, New York, NY VL - 195 SN - 0179-5953, 0179-5953 KW - soils KW - water quality KW - concentration KW - biodegradation KW - Plantae KW - photochemistry KW - pollution KW - hydrolysis KW - adsorption KW - solubility KW - lambda-cyhalothrin KW - biota KW - bioaccumulation KW - organic compounds KW - toxicity KW - photolysis KW - agrochemicals KW - runoff KW - sediments KW - pesticides KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50619180?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reviews+of+Environmental+Contamination+and+Toxicology&rft.atitle=Environmental+chemistry%2C+ecotoxocity%2C+and+fate+of+lambda-cyhalothrin&rft.au=He%2C+Li-Ming%3BTroiano%2C+John%3BWang%2C+Albert%3BGoh%2C+Kean&rft.aulast=He&rft.aufirst=Li-Ming&rft.date=2008-01-01&rft.volume=195&rft.issue=&rft.spage=71&rft.isbn=&rft.btitle=&rft.title=Reviews+of+Environmental+Contamination+and+Toxicology&rft.issn=01795953&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 67 N1 - PubXState - NY N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - adsorption; agrochemicals; bioaccumulation; biodegradation; biota; concentration; hydrolysis; lambda-cyhalothrin; organic compounds; pesticides; photochemistry; photolysis; Plantae; pollution; runoff; sediments; soils; solubility; toxicity; water quality ER - TY - JOUR T1 - Early-warning monitoring for water security; evaluation of water-quality variability in a distribution system AN - 50616121; 2008-111860 JF - Scientific Investigations Report AU - Baker, R J AU - Vowinkel, E F AU - Bukhari, Z AU - McKenna, S A AU - Janke, R J A2 - Buxton, Herbert T. A2 - Griffin, Dale W. A2 - Pierce, Brenda S. Y1 - 2008 PY - 2008 DA - 2008 SP - 18 EP - 19 PB - U. S. Geological Survey, Reston, VA KW - hydrology KW - water quality KW - survey organizations KW - monitoring KW - U. S. Geological Survey KW - government agencies KW - water management KW - U. S. Environmental Protection Agency KW - pollution KW - drinking water KW - variations KW - warning systems KW - water pollution KW - USGS KW - instruments KW - public health KW - 21:Hydrogeology KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50616121?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scientific+Investigations+Report&rft.atitle=Early-warning+monitoring+for+water+security%3B+evaluation+of+water-quality+variability+in+a+distribution+system&rft.au=Baker%2C+R+J%3BVowinkel%2C+E+F%3BBukhari%2C+Z%3BMcKenna%2C+S+A%3BJanke%2C+R+J&rft.aulast=Baker&rft.aufirst=R&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=18&rft.isbn=&rft.btitle=&rft.title=Scientific+Investigations+Report&rft.issn=&rft_id=info:doi/ L2 - http://pubs.usgs.gov/sir/2008/5022/ http://pubs.usgs.gov/sir/ LA - English DB - GeoRef N1 - Conference title - Second national conference on USGS health-related research N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - VA N1 - SuppNotes - Accessed on July 1, 2008 N1 - Last updated - 2012-06-07 N1 - CODEN - #06439 N1 - SubjectsTermNotLitGenreText - drinking water; government agencies; hydrology; instruments; monitoring; pollution; public health; survey organizations; U. S. Environmental Protection Agency; U. S. Geological Survey; USGS; variations; warning systems; water management; water pollution; water quality ER - TY - JOUR T1 - Exposure and effects of dioxins on birds; a case study using tree swallows AN - 50614994; 2008-111873 JF - Scientific Investigations Report AU - Custer, Thomas W AU - Custer, Christine M AU - Rosiu, Cornell J A2 - Buxton, Herbert T. A2 - Griffin, Dale W. A2 - Pierce, Brenda S. Y1 - 2008 PY - 2008 DA - 2008 SP - 24 EP - 25 PB - U. S. Geological Survey, Reston, VA KW - toxic materials KW - Chordata KW - living taxa KW - pollutants KW - pollution KW - bioavailability KW - dioxins KW - biota KW - case studies KW - Aves KW - organic compounds KW - ecology KW - Vertebrata KW - USGS KW - Tetrapoda KW - Tachycineta bicolor KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50614994?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scientific+Investigations+Report&rft.atitle=Exposure+and+effects+of+dioxins+on+birds%3B+a+case+study+using+tree+swallows&rft.au=Custer%2C+Thomas+W%3BCuster%2C+Christine+M%3BRosiu%2C+Cornell+J&rft.aulast=Custer&rft.aufirst=Thomas&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=24&rft.isbn=&rft.btitle=&rft.title=Scientific+Investigations+Report&rft.issn=&rft_id=info:doi/ L2 - http://pubs.usgs.gov/sir/2008/5022/ http://pubs.usgs.gov/sir/ LA - English DB - GeoRef N1 - Conference title - Second national conference on USGS health-related research N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - VA N1 - SuppNotes - Accessed on July 1, 2008 N1 - Last updated - 2012-06-07 N1 - CODEN - #06439 N1 - SubjectsTermNotLitGenreText - Aves; bioavailability; biota; case studies; Chordata; dioxins; ecology; living taxa; organic compounds; pollutants; pollution; Tachycineta bicolor; Tetrapoda; toxic materials; USGS; Vertebrata ER - TY - JOUR T1 - Mapping mercury sensitivity of aquatic ecosystems across the contiguous United States AN - 50613669; 2008-111877 JF - Scientific Investigations Report AU - Krabbenhoft, David P AU - Booth, Nathan L AU - Saltman, Tamara A2 - Buxton, Herbert T. A2 - Griffin, Dale W. A2 - Pierce, Brenda S. Y1 - 2008 PY - 2008 DA - 2008 SP - 26 EP - 27 PB - U. S. Geological Survey, Reston, VA KW - United States KW - food chains KW - pollutants KW - pollution KW - mapping KW - ecosystems KW - bioavailability KW - organo-metallics KW - biota KW - spatial distribution KW - geographic information systems KW - methylmercury KW - deposition KW - metals KW - information systems KW - USGS KW - aquatic environment KW - mercury KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50613669?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scientific+Investigations+Report&rft.atitle=Mapping+mercury+sensitivity+of+aquatic+ecosystems+across+the+contiguous+United+States&rft.au=Krabbenhoft%2C+David+P%3BBooth%2C+Nathan+L%3BSaltman%2C+Tamara&rft.aulast=Krabbenhoft&rft.aufirst=David&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Scientific+Investigations+Report&rft.issn=&rft_id=info:doi/ L2 - http://pubs.usgs.gov/sir/2008/5022/ http://pubs.usgs.gov/sir/ LA - English DB - GeoRef N1 - Conference title - Second national conference on USGS health-related research N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - VA N1 - SuppNotes - Accessed on July 1, 2008 N1 - Last updated - 2012-06-07 N1 - CODEN - #06439 N1 - SubjectsTermNotLitGenreText - aquatic environment; bioavailability; biota; deposition; ecosystems; food chains; geographic information systems; information systems; mapping; mercury; metals; methylmercury; organo-metallics; pollutants; pollution; spatial distribution; United States; USGS ER - TY - JOUR T1 - Polybrominated diphenyl ethers (PBDEs) in sediment by salinity and land-use type from Australia AN - 50605446; 2008-114331 JF - Environment International AU - Toms, Leisa-Maree L AU - Mortimer, Munro AU - Symons, Robert K AU - Paepke, Olaf AU - Mueller, Jochen F Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 58 EP - 66 PB - Elsevier, New York-Oxford VL - 34 IS - 1 SN - 0160-4120, 0160-4120 KW - salinity KW - urban environment KW - bioaccumulation KW - ethers KW - PBDEs KW - sediments KW - Australia KW - soils KW - concentration KW - toxic materials KW - food chains KW - Australasia KW - pollutants KW - human activity KW - pollution KW - biota KW - flame retardants KW - polybrominated diphenyl ethers KW - organic compounds KW - industrial waste KW - risk assessment KW - waste disposal KW - aquatic environment KW - point sources KW - land use KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50605446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environment+International&rft.atitle=Polybrominated+diphenyl+ethers+%28PBDEs%29+in+sediment+by+salinity+and+land-use+type+from+Australia&rft.au=Toms%2C+Leisa-Maree+L%3BMortimer%2C+Munro%3BSymons%2C+Robert+K%3BPaepke%2C+Olaf%3BMueller%2C+Jochen+F&rft.aulast=Toms&rft.aufirst=Leisa-Maree&rft.date=2008-01-01&rft.volume=34&rft.issue=1&rft.spage=58&rft.isbn=&rft.btitle=&rft.title=Environment+International&rft.issn=01604120&rft_id=info:doi/10.1016%2Fj.envint.2007.07.003 L2 - http://www.sciencedirect.com/science/journal/01604120 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 39 N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - aquatic environment; Australasia; Australia; bioaccumulation; biota; concentration; ethers; flame retardants; food chains; human activity; industrial waste; land use; organic compounds; PBDEs; point sources; pollutants; pollution; polybrominated diphenyl ethers; risk assessment; salinity; sediments; soils; toxic materials; urban environment; waste disposal DO - http://dx.doi.org/10.1016/j.envint.2007.07.003 ER - TY - JOUR T1 - Are environmental exposures to chlorophenoxy herbicides associated with adverse human health effects? AN - 50594310; 2008-116638 JF - Scientific Investigations Report AU - Schreinemachers, Dina M A2 - Helterbrand, W. Steve A2 - Sieverling, Jennifer B. Y1 - 2008 PY - 2008 DA - 2008 SP - 34 EP - 35 PB - U. S. Geological Survey, Reston, VA KW - United States KW - pollutants KW - herbicides KW - agriculture KW - pollution KW - diseases KW - biomarkers KW - environmental effects KW - chlorophenoxy KW - pesticides KW - USGS KW - public health KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50594310?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scientific+Investigations+Report&rft.atitle=Are+environmental+exposures+to+chlorophenoxy+herbicides+associated+with+adverse+human+health+effects%3F&rft.au=Schreinemachers%2C+Dina+M&rft.aulast=Schreinemachers&rft.aufirst=Dina&rft.date=2008-01-01&rft.volume=&rft.issue=&rft.spage=34&rft.isbn=&rft.btitle=&rft.title=Scientific+Investigations+Report&rft.issn=&rft_id=info:doi/ L2 - http://pubs.usgs.gov/sir/2008/5074/ http://pubs.usgs.gov/sir/ LA - English DB - GeoRef N1 - Conference title - U. S. Geological Survey Seventh biennial geographic information science workshop N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - PubXState - VA N1 - SuppNotes - Accessed on Aug. 18, 2008 N1 - Last updated - 2012-06-07 N1 - CODEN - #06439 N1 - SubjectsTermNotLitGenreText - agriculture; biomarkers; chlorophenoxy; diseases; environmental effects; herbicides; pesticides; pollutants; pollution; public health; United States; USGS ER - TY - JOUR T1 - CO (sub 2) degassing over seismic areas; the role of mechanochemical production at the study case of Central Apennines AN - 50586350; 2008-118331 JF - Pure and Applied Geophysics AU - Italiano, F AU - Martinelli, G AU - Plescia, P A2 - Perez, Nemesio M. A2 - Gurrieri, Sergio A2 - King, Chi-Yu A2 - Taran, Yuri Y1 - 2008 PY - 2008 DA - 2008 SP - 75 EP - 94 PB - Birkhaeuser, Basel VL - 165 IS - 1 SN - 0033-4553, 0033-4553 KW - Tuscany Italy KW - magmatism KW - Central Apennines KW - mantle KW - Europe KW - Marches Italy KW - Italy KW - Southern Europe KW - gases KW - carbon dioxide KW - geothermal fields KW - Larderello KW - Apennines KW - seismicity KW - volume KW - Umbria Italy KW - energy KW - degassing KW - 19:Seismology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50586350?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pure+and+Applied+Geophysics&rft.atitle=CO+%28sub+2%29+degassing+over+seismic+areas%3B+the+role+of+mechanochemical+production+at+the+study+case+of+Central+Apennines&rft.au=Italiano%2C+F%3BMartinelli%2C+G%3BPlescia%2C+P&rft.aulast=Italiano&rft.aufirst=F&rft.date=2008-01-01&rft.volume=165&rft.issue=1&rft.spage=75&rft.isbn=&rft.btitle=&rft.title=Pure+and+Applied+Geophysics&rft.issn=00334553&rft_id=info:doi/10.1007%2Fs00024-007-0291-7 L2 - http://link.springer.de/link/service/journals/00024/index.htm LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 47 N1 - Document feature - illus. incl. 5 tables, geol. sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - PAGYAV N1 - SubjectsTermNotLitGenreText - Apennines; carbon dioxide; Central Apennines; degassing; energy; Europe; gases; geothermal fields; Italy; Larderello; magmatism; mantle; Marches Italy; seismicity; Southern Europe; Tuscany Italy; Umbria Italy; volume DO - http://dx.doi.org/10.1007/s00024-007-0291-7 ER - TY - JOUR T1 - Impervious surface impacts to runoff and sediment discharge under laboratory rainfall simulation AN - 50584133; 2008-099067 AB - Urbanization of watersheds previously managed for agricultural uses results in hydrologic changes associated with increased flooding and erosion. Few studies have been conducted to quantify these effects under controlled conditions and standard rainfall simulation methodologies have not been previously established. In this study, a laboratory rainfall simulation procedure was developed and utilized to evaluate hydrologic and sheet erosional responses to various configurations of impervious surface cover at the small scale. Runoff and sediment losses from a sloped (5%) cascade of soil boxes having 50% impervious cover located at the top of the slope or at the bottom of the slope, or having 0% impervious cover were measured. Results indicate that the 50% upslope impervious treatment generated sediment at 3-5 times the rate of the 50% downslope impervious treatment. Upslope impervious cover resulted in initially lower water runoff rates than channel development, but this effect narrowed or reversed with continued rainfall. These results suggest that upslope impervious surfaces may represent a larger total on-site erosion risk than equivalent impervious surfaces located at lower positions along the slope, especially under high antecedent soil moisture and/or high intensity rainfall. JF - Catena (Giessen) AU - Pappas, E A AU - Smith, D R AU - Huang, C AU - Shuster, W D AU - Bonta, J V Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 146 EP - 152 PB - Elsevier VL - 72 IS - 1 SN - 0341-8162, 0341-8162 KW - United States KW - hydrology KW - central Ohio KW - experimental studies KW - impermeable surfaces KW - Coshocton County Ohio KW - rainfall KW - watersheds KW - unsaturated zone KW - urbanization KW - simulation KW - physical models KW - laboratory studies KW - Coshocton Ohio KW - hydrologic cycle KW - land use KW - Ohio KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50584133?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Catena+%28Giessen%29&rft.atitle=Impervious+surface+impacts+to+runoff+and+sediment+discharge+under+laboratory+rainfall+simulation&rft.au=Pappas%2C+E+A%3BSmith%2C+D+R%3BHuang%2C+C%3BShuster%2C+W+D%3BBonta%2C+J+V&rft.aulast=Pappas&rft.aufirst=E&rft.date=2008-01-01&rft.volume=72&rft.issue=1&rft.spage=146&rft.isbn=&rft.btitle=&rft.title=Catena+%28Giessen%29&rft.issn=03418162&rft_id=info:doi/10.1016%2Fj.catena.2007.05.001 L2 - http://www.sciencedirect.com/science/journal/03418162 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2008-01-01 N1 - Number of references - 21 N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - CODEN - CIJPD3 N1 - SubjectsTermNotLitGenreText - central Ohio; Coshocton County Ohio; Coshocton Ohio; experimental studies; hydrologic cycle; hydrology; impermeable surfaces; laboratory studies; land use; Ohio; physical models; rainfall; simulation; United States; unsaturated zone; urbanization; watersheds DO - http://dx.doi.org/10.1016/j.catena.2007.05.001 ER - TY - JOUR T1 - Globally elevated titanium, tantalum, and niobium (TITAN) in ocean island basalts with high (super 3) He/ (super 4) He AN - 50540183; 2009-008340 AB - We report evidence for a global Ti, Ta, and Nb (TITAN) enriched reservoir sampled by ocean island basalts (OIBs) with high (super 3) He/ (super 4) He ratios, an isotopic signature associated with the deep mantle. Excesses of Ti (and to a lesser degree Nb and Ta) correlate remarkably well with (super 3) He/ (super 4) He in a data set of global OIBs, demonstrating that a major element signature is associated with the high (super 3) He/ (super 4) He mantle. Additionally, we find that OIBs with high (super 3) He/ (super 4) He ratios have moderately radiogenic (super 187) Os/ (super 188) Os (>0.135). The TITAN enrichment and radiogenic (super 187) Os/ (super 188) Os in high (super 3) He/ (super 4) He OIBs indicate that they are melts of a mantle domain that hosts a nonprimitive (nonchondritic) component. The observation of TITAN enrichment in the high (super 3) He/ (super 4) He mantle may be important in balancing the Earth's budget for the TITAN elements. Understanding the origin of the TITAN enrichment is important for constraining the evolution of the enigmatic high (super 3) He/ (super 4) He mantle domain. JF - Geochemistry, Geophysics, Geosystems - G3 AU - Jackson, Matthew G AU - Hart, Stanley R AU - Saal, Alberto E AU - Shimizu, Nobumichi AU - Kurz, Mark D AU - Blusztajn, Jerzy S AU - Skovgaard, Anna C Y1 - 2008 PY - 2008 DA - 2008 EP - Citation Q04027 PB - American Geophysical Union and The Geochemical Society VL - 9 IS - 4 KW - volcanic rocks KW - isotopes KW - igneous rocks KW - mantle KW - Os-188/Os-187 KW - platinum group KW - stable isotopes KW - major elements KW - noble gases KW - metamorphic rocks KW - basalts KW - FOZO KW - helium KW - tantalum KW - trace elements KW - geochemistry KW - isotope ratios KW - global KW - niobium KW - titanium KW - metals KW - focus zone KW - osmium KW - He-4/He-3 KW - ocean-island basalts KW - eclogite KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50540183?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geochemistry%2C+Geophysics%2C+Geosystems+-+G3&rft.atitle=Globally+elevated+titanium%2C+tantalum%2C+and+niobium+%28TITAN%29+in+ocean+island+basalts+with+high+%28super+3%29+He%2F+%28super+4%29+He&rft.au=Jackson%2C+Matthew+G%3BHart%2C+Stanley+R%3BSaal%2C+Alberto+E%3BShimizu%2C+Nobumichi%3BKurz%2C+Mark+D%3BBlusztajn%2C+Jerzy+S%3BSkovgaard%2C+Anna+C&rft.aulast=Jackson&rft.aufirst=Matthew&rft.date=2008-01-01&rft.volume=9&rft.issue=4&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Geochemistry%2C+Geophysics%2C+Geosystems+-+G3&rft.issn=1525-2027&rft_id=info:doi/10.1029%2F2007GC001876 L2 - http://g-cubed.org LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2009-01-01 N1 - Number of references - 104 N1 - Document feature - illus. incl. 3 tables N1 - SuppNotes - Includes appendices N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - basalts; eclogite; focus zone; FOZO; geochemistry; global; He-4/He-3; helium; igneous rocks; isotope ratios; isotopes; major elements; mantle; metals; metamorphic rocks; niobium; noble gases; ocean-island basalts; Os-188/Os-187; osmium; platinum group; stable isotopes; tantalum; titanium; trace elements; volcanic rocks DO - http://dx.doi.org/10.1029/2007GC001876 ER - TY - JOUR T1 - Environmental fate and toxicology of carbaryl AN - 50441489; 2009-046527 JF - Reviews of Environmental Contamination and Toxicology AU - Gunasekara, Amrith S AU - Rubin, Andrew L AU - Goh, Kean S AU - Spurlock, Frank C AU - Tjeerdema, Ronald S Y1 - 2008 PY - 2008 DA - 2008 SP - 95 EP - 121 PB - Springer, New York, NY VL - 196 SN - 0179-5953, 0179-5953 KW - soils KW - chlorinated hydrocarbons KW - insecticides KW - degradation KW - metabolism KW - surface water KW - pollution KW - organochlorine pesticides KW - solubility KW - biota KW - bioaccumulation KW - habitat KW - organic compounds KW - detection KW - chemical properties KW - halogenated hydrocarbons KW - risk assessment KW - carbaryl KW - carbamates KW - pesticides KW - kinetics KW - microorganisms KW - dynamic properties KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50441489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reviews+of+Environmental+Contamination+and+Toxicology&rft.atitle=Environmental+fate+and+toxicology+of+carbaryl&rft.au=Gunasekara%2C+Amrith+S%3BRubin%2C+Andrew+L%3BGoh%2C+Kean+S%3BSpurlock%2C+Frank+C%3BTjeerdema%2C+Ronald+S&rft.aulast=Gunasekara&rft.aufirst=Amrith&rft.date=2008-01-01&rft.volume=196&rft.issue=&rft.spage=95&rft.isbn=&rft.btitle=&rft.title=Reviews+of+Environmental+Contamination+and+Toxicology&rft.issn=01795953&rft_id=info:doi/10.1007%2F978-0-3878-78444-1_4 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 32 N1 - PubXState - NY N1 - Document feature - illus. incl. 6 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - bioaccumulation; biota; carbamates; carbaryl; chemical properties; chlorinated hydrocarbons; degradation; detection; dynamic properties; habitat; halogenated hydrocarbons; insecticides; kinetics; metabolism; microorganisms; organic compounds; organochlorine pesticides; pesticides; pollution; risk assessment; soils; solubility; surface water DO - http://dx.doi.org/10.1007/978-0-3878-78444-1_4 ER - TY - JOUR T1 - Enumeration and characterization of bacteria indigenous to a shallow water-table aquifer AN - 50428412; 2009-049893 JF - Benchmark Papers in Hydrology AU - Wilson, John T AU - McNabb, James F AU - Balkwill, David L AU - Ghiorse, William C A2 - Anderson, Mary P. Y1 - 2008 PY - 2008 DA - 2008 SP - 500 EP - 508 PB - IAHS Press, Centre for Ecology and Hydrology, Wallingford VL - 3 SN - 1993-4572, 1993-4572 KW - United States KW - chlorinated hydrocarbons KW - Pontotoc County Oklahoma KW - chlorobenzene KW - floodplains KW - ground water KW - decontamination KW - halogenated hydrocarbons KW - ecology KW - water pollution KW - biodegradation KW - pollutants KW - Lula Oklahoma KW - pollution KW - aquifers KW - case studies KW - water table KW - volatiles KW - organic compounds KW - Oklahoma KW - bacteria KW - volatile organic compounds KW - fluvial features KW - shallow aquifers KW - aquatic environment KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50428412?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Benchmark+Papers+in+Hydrology&rft.atitle=Enumeration+and+characterization+of+bacteria+indigenous+to+a+shallow+water-table+aquifer&rft.au=Wilson%2C+John+T%3BMcNabb%2C+James+F%3BBalkwill%2C+David+L%3BGhiorse%2C+William+C&rft.aulast=Wilson&rft.aufirst=John&rft.date=2008-01-01&rft.volume=3&rft.issue=&rft.spage=500&rft.isbn=&rft.btitle=&rft.title=Benchmark+Papers+in+Hydrology&rft.issn=19934572&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 20 N1 - Document feature - illus. incl. 2 tables N1 - SuppNotes - Reprinted from Ground Water, Vol. 21, p. 134-142, 1983 N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - aquatic environment; aquifers; bacteria; biodegradation; case studies; chlorinated hydrocarbons; chlorobenzene; decontamination; ecology; floodplains; fluvial features; ground water; halogenated hydrocarbons; Lula Oklahoma; Oklahoma; organic compounds; pollutants; pollution; Pontotoc County Oklahoma; shallow aquifers; United States; volatile organic compounds; volatiles; water pollution; water table ER - TY - JOUR T1 - Global 3-D land-ocean-atmosphere model for mercury; present-day versus preindustrial cycles and anthropogenic enrichment factors for deposition AN - 50256702; 2009-080198 JF - Global Biogeochemical Cycles AU - Selin, Noelle E AU - Jacob, Daniel J AU - Yantosca, Robert M AU - Strode, Sarah AU - Jaegle, Lyatt AU - Sunderland, Elsie M Y1 - 2008 PY - 2008 DA - 2008 EP - Citation GB2011 PB - American Geophysical Union, Washington, DC VL - 22 IS - 2 SN - 0886-6236, 0886-6236 KW - United States KW - soils KW - three-dimensional models KW - human activity KW - atmosphere KW - atmospheric precipitation KW - geochemical cycle KW - volatilization KW - quantitative analysis KW - deposition KW - metals KW - world ocean KW - mercury KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50256702?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+Biogeochemical+Cycles&rft.atitle=Global+3-D+land-ocean-atmosphere+model+for+mercury%3B+present-day+versus+preindustrial+cycles+and+anthropogenic+enrichment+factors+for+deposition&rft.au=Selin%2C+Noelle+E%3BJacob%2C+Daniel+J%3BYantosca%2C+Robert+M%3BStrode%2C+Sarah%3BJaegle%2C+Lyatt%3BSunderland%2C+Elsie+M&rft.aulast=Selin&rft.aufirst=Noelle&rft.date=2008-01-01&rft.volume=22&rft.issue=2&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Global+Biogeochemical+Cycles&rft.issn=08866236&rft_id=info:doi/10.1029%2F2007GB003040 L2 - http://www.agu.org/journals/gb/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2009-01-01 N1 - PubXState - DC N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - atmosphere; atmospheric precipitation; deposition; geochemical cycle; human activity; mercury; metals; quantitative analysis; soils; three-dimensional models; United States; volatilization; world ocean DO - http://dx.doi.org/10.1029/2007GB003040 ER - TY - JOUR T1 - Redesign of the 2005 Pollution Abatement Costs and Expenditure Survey AN - 37257673; 3927062 AB - This paper presents the results of a comprehensive redevelopment and evaluation effort led by the U.S. Environmental Protection Agency (EPA) to assess the accuracy of the responses to the Pollution Abatement Costs and Expenditures (PACE) survey. The data collected by the PACE survey is important because it is the only comprehensive source of pollution abatement costs and expenditures related to environmental protection in the U.S. manufacturing sector. The PACE Survey has been administered over twenty times since 1973, yet until now, the accuracy of the survey responses has never been formally evaluated. The methods used to evaluate the survey include one-on-one interviews and site visits with manufacturing facilities to develop independent cost estimates which were compared to reported survey responses. Overall this study finds, assuming a reasonable margin of error, that the PACE survey responses reflect actual pollution abatement capital expenditures and operating costs. In addition, these interactions with facilities had a major impact on the design of the 2005 PACE survey and are also discussed in this paper. Reprinted by permission of IOS Press JF - Journal of economic and social measurement AU - Gallaher, M P AU - Morgan, C L AU - Shadbegian, R J AD - US Environmental Protection Agency Y1 - 2008 PY - 2008 DA - 2008 SP - 309 EP - 360 VL - 33 IS - 4 SN - 0747-9662, 0747-9662 KW - Economics KW - Political Science KW - Emissions trading KW - Cost analysis KW - Surveys KW - U.S.A. KW - Industrial pollution KW - Environmental policy KW - Pollution control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37257673?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+economic+and+social+measurement&rft.atitle=Redesign+of+the+2005+Pollution+Abatement+Costs+and+Expenditure+Survey&rft.au=Gallaher%2C+M+P%3BMorgan%2C+C+L%3BShadbegian%2C+R+J&rft.aulast=Gallaher&rft.aufirst=M&rft.date=2008-01-01&rft.volume=33&rft.issue=4&rft.spage=309&rft.isbn=&rft.btitle=&rft.title=Journal+of+economic+and+social+measurement&rft.issn=07479662&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - Emissions trading; 9819 9818; 12429; 6392 9818; 2920 971 2934 3883; 4336 5574 10472; 433 293 14 ER - TY - JOUR T1 - Providing a framework for accountability and learning in environmental research AN - 36980485; 3778616 JF - Administration [Dublin] AU - O'Leary, Gerard AU - Boyle, Richard AU - Donlon, Brian AU - Sheils, Lisa AD - Environmental Protection Agency ; Institute of Public Administration Y1 - 2008 PY - 2008 DA - 2008 SP - 159 EP - 170 VL - 55 IS - 4 SN - 0001-8325, 0001-8325 KW - Political Science KW - Environment KW - Learning KW - Public administration KW - Accountability KW - Environmental protection UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36980485?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Administration+%5BDublin%5D&rft.atitle=Providing+a+framework+for+accountability+and+learning+in+environmental+research&rft.au=O%27Leary%2C+Gerard%3BBoyle%2C+Richard%3BDonlon%2C+Brian%3BSheils%2C+Lisa&rft.aulast=O%27Leary&rft.aufirst=Gerard&rft.date=2008-01-01&rft.volume=55&rft.issue=4&rft.spage=159&rft.isbn=&rft.btitle=&rft.title=Administration+%5BDublin%5D&rft.issn=00018325&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 7278 12929 7073; 4309; 525 9705; 4339; 10424 567 ER - TY - JOUR T1 - Modelling mercury deposition through latent space-time processes AN - 36839916; 3521912 AB - The paper provides a space-time process model for total wet mercury deposition. Key methodological features that are introduced include direct modelling of deposition rather than of expected deposition, the utilization of precipitation information (there is no deposition without precipitation) without having to construct a precipitation model and the handling of point masses at 0 in the distributions of both precipitation and deposition. The result is a specification that enables spatial interpolation and temporal prediction of deposition as well as aggregation in space or time to see patterns and trends in deposition. We use weekly deposition monitoring data from the National Atmospheric Deposition Program-Mercury Deposition Network for 2003 restricted to the eastern USA and Canada. Our spatiotemporal hierarchical model allows us to interpolate to arbitrary locations and, hence, to an arbitrary grid, enabling weekly deposition surfaces (with associated uncertainties) for this region. It also allows us to aggregate weekly depositions at coarser, quarterly and annual, temporal levels. Reprinted by permission of Blackwell Publishers JF - Journal of the Royal Statistical Society AU - Rappold, A G AU - Gelfand, A E AU - Holland, D M AD - US Environmental Protection Agency ; Duke University Y1 - 2008 PY - 2008 DA - 2008 SP - 187 EP - 206 VL - 57 IS - 2 SN - 0035-9254, 0035-9254 KW - Economics KW - Sociology KW - Mercury KW - Metals KW - Canada KW - Environmental economics KW - Distribution KW - Statistical models KW - Geology KW - U.S.A. KW - Spatial models UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36839916?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Royal+Statistical+Society&rft.atitle=Modelling+mercury+deposition+through+latent+space-time+processes&rft.au=Rappold%2C+A+G%3BGelfand%2C+A+E%3BHolland%2C+D+M&rft.aulast=Rappold&rft.aufirst=A&rft.date=2008-01-01&rft.volume=57&rft.issue=2&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Royal+Statistical+Society&rft.issn=00359254&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12230 8163; 4316 4025; 5476 8573 11325; 7985 8101; 3641 12233; 12106 8163; 433 293 14; 75 293 14 ER - TY - JOUR T1 - Why have traffic fatalities declined in industrialised countries? Implications for pedestrians and vehicle occupants AN - 36803684; 3506114 AB - This paper examines the relationship between traffic fatalities and income for vehicle occupants and pedestrians and investigates factors underlying the decline in fatalities per vehicle kilometre travelled (VKT) using panel data for 32 countries from 1963-2002. Results suggest the downward-sloping portion of the curve relating traffic fatalities per capita to per capita income is due primarily to improved pedestrian safety (Kopits and Cropper, 2005a). More detailed models shed light on factors influencing pedestrian fatalities/VKT but some of the long-term improvement remains unexplained. Declines in occupant fatalities/VKT are explained primarily by reductions in alcohol abuse, improved medical services, and fewer young drivers. JF - Journal of transport economics and policy AU - Kopits, E AU - Cropper, M AD - US Environmental Protection Agency ; University of Maryland Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 129 EP - 154 VL - 42 IS - 1 SN - 0022-5258, 0022-5258 KW - Economics KW - Industrialized countries KW - Safety KW - Transport economics KW - Road accidents KW - Road transport KW - U.S.A. KW - Panel data KW - Cross-national analysis KW - Traffic UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36803684?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+transport+economics+and+policy&rft.atitle=Why+have+traffic+fatalities+declined+in+industrialised+countries%3F+Implications+for+pedestrians+and+vehicle+occupants&rft.au=Kopits%2C+E%3BCropper%2C+M&rft.aulast=Kopits&rft.aufirst=E&rft.date=2008-01-01&rft.volume=42&rft.issue=1&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=Journal+of+transport+economics+and+policy&rft.issn=00225258&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12940 4025; 11229; 11086 12937; 11080 524; 12889 12937; 9144 8160 8163; 3060 971; 6427 2958 12092; 433 293 14 ER - TY - JOUR T1 - Turkey Fecal Microbial Community Structure and Functional Gene Diversity Revealed by 16S rRNA Gene and Metagenomic Sequences AN - 21116854; 11331105 AB - The primary goal of this study was to better understand the microbial composition and functional genetic diversity associated with turkey fecal communities. To achieve this, 16S rRNA gene and metagenomic clone libraries were sequenced from turkey fecal samples. The analysis of 382 16S rRNA gene sequences showed that the most abundant bacteria were closely related to Lactobacillales (47%), Bacillales (31%), and Clostridiales (11%). Actinomycetales, Enterobacteriales, and Bacteroidales sequences were also identified, but represented a smaller part of the community. The analysis of 379 metagenomic sequences showed that most clones were similar to bacterial protein sequences (58%). Bacteriophage (10%) and avian viruses (3%) sequences were also represented. Of all metagenomic clones potentially encoding for bacterial proteins, most were similar to low G+C Gram-positive bacterial proteins, particularly from Lactobacillales (50%), Bacillales (11%), and Clostridiales (8%). Bioinformatic analyses suggested the presence of genes encoding for membrane proteins, lipoproteins, hydrolases, and functional genes associated with the metabolism of nitrogen and sulfur containing compounds. The results from this study further confirmed the predominance of Firmicutes in the avian gut and highlight the value of coupling 16S rRNA gene and metagenomic sequencing data analysis to study the microbial composition of avian fecal microbial communities. JF - Journal of Microbiology AU - Lu, J AU - Domingo, J S AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, MS-387, Cincinnati, OH, USA Y1 - 2008 PY - 2008 DA - 2008 SP - 469 EP - 477 VL - 46 IS - 5 SN - 1225-8873, 1225-8873 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Genetics Abstracts; Microbiology Abstracts B: Bacteriology; Biochemistry Abstracts 2: Nucleic Acids KW - Sulfur KW - Phages KW - Data processing KW - Actinomycetales KW - Genetic diversity KW - Firmicutes KW - Membrane proteins KW - hydrolase KW - Digestive tract KW - Community structure KW - Lipoproteins KW - Clostridiales KW - Bioinformatics KW - rRNA 16S KW - Metabolism KW - Nitrogen KW - V 22410:Animal Diseases KW - N 14815:Nucleotide Sequence KW - J 02430:Symbiosis, Antibiosis & Phages KW - G 07760:Viruses & Phages KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21116854?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiology&rft.atitle=Turkey+Fecal+Microbial+Community+Structure+and+Functional+Gene+Diversity+Revealed+by+16S+rRNA+Gene+and+Metagenomic+Sequences&rft.au=Lu%2C+J%3BDomingo%2C+J+S&rft.aulast=Lu&rft.aufirst=J&rft.date=2008-01-01&rft.volume=46&rft.issue=5&rft.spage=469&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiology&rft.issn=12258873&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Phages; Sulfur; Data processing; Genetic diversity; Membrane proteins; hydrolase; Digestive tract; Community structure; Lipoproteins; Bioinformatics; rRNA 16S; Metabolism; Nitrogen; Actinomycetales; Clostridiales; Firmicutes ER - TY - JOUR T1 - Mode of Action Frameworks: A Critical Analysis AN - 21063026; 8609888 AB - Mode of action (MOA) information is increasingly being applied in human health risk assessment. The MOA can inform issues such as the relevance of observed effects in laboratory animals to humans, and the variability of response within the human population. Several collaborative groups have developed frameworks for analyzing and utilizing MOA information in human health risk assessment of environmental carcinogens and toxins, including the International Programme on Chemical Safety, International Life Sciences Institute, and U.S. Environmental Protection Agency. With the goal of identifying gaps and opportunities for progress, we critically evaluate several of these MOA frameworks. Despite continued improvement in incorporating biological data in human health risk assessment, several notable challenges remain. These include articulation of the significant role of scientific judgment in establishing an MOA and its relevance to humans. In addition, binary (yes/no) decisions can inappropriately exclude consideration of data that may nonetheless be informative to the overall assessment of risk. Indeed, the frameworks lack a broad consideration of known causes of human disease and the potential for chemical effects to act additively with these as well as endogenous background processes. No integrated analysis of the impact of multiple MOAs over the same dose range, or of varying MOAs at different life stages, is included. Separate consideration of each MOA and outcome limits understanding of how multiple metabolites, modes, and toxicity pathways contribute to the toxicological profile of the chemical. An extension of the analyses across outcomes with common modes is also needed. JF - Journal of Toxicology and Environmental Health, Part B: Critical Reviews AU - Guyton, Kathryn Z AU - Barone Jr, Stanley AU - Brown, Rebecca C AU - Euling, Susan Y AU - Jinot, Jennifer AU - Makris, Susan AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, USA Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 16 EP - 31 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 11 IS - 1 SN - 1093-7404, 1093-7404 KW - Toxicology Abstracts KW - Risk assessment KW - Data processing KW - Information processing KW - Laboratory animals KW - Developmental stages KW - Metabolites KW - Toxicity KW - Carcinogens KW - Toxins KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21063026?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+B%3A+Critical+Reviews&rft.atitle=Mode+of+Action+Frameworks%3A+A+Critical+Analysis&rft.au=Guyton%2C+Kathryn+Z%3BBarone+Jr%2C+Stanley%3BBrown%2C+Rebecca+C%3BEuling%2C+Susan+Y%3BJinot%2C+Jennifer%3BMakris%2C+Susan&rft.aulast=Guyton&rft.aufirst=Kathryn&rft.date=2008-01-01&rft.volume=11&rft.issue=1&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+B%3A+Critical+Reviews&rft.issn=10937404&rft_id=info:doi/10.1080%2F10937400701600321 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Data processing; Information processing; Laboratory animals; Developmental stages; Metabolites; Carcinogens; Toxicity; Toxins DO - http://dx.doi.org/10.1080/10937400701600321 ER - TY - JOUR T1 - Collection of ambient particulate matter by porous vegetation barriers: Sampling and characterization methods AN - 21021842; 8431086 AB - Sampling and characterization methods for assessing the effect of vegetative barriers on particulate matter (PM10) concentrations and functional group composition were developed and applied in a case study. Ambient PM10 was concurrently sampled upwind and downwind of a hawthorn hedge at a rural location in the UK. Fourier transform infrared (FTIR) spectra of PM10 samples were collected to characterize the functional group composition. Absorbances associated with sulfate, nitrate, ammonium, aliphatic carbon-hydrogen, and carbonyl functional groups were observed in the FTIR spectra. Calculations with gravimetric measurements show that the hedge collects PM10 mass with a collection efficiency of 34% on average. FTIR results suggest that individual functional groups might exhibit different behavior in the hedge, but further method development and sampling is necessary to calculate functional group results with more confidence. Current results show the potential of using hedges to mitigate ambient concentrations of airborne PM10, and applying these methods to a more statistically robust sample size is anticipated to aid in elucidating physico-chemical mechanisms driving collection of PM10 by hedge elements. JF - Journal of Aerosol Science AU - Tiwary, Abhishek AU - Reff, Adam AU - Colls, Jeremy J AD - School of Chemical Engineering and Analytical Sciences, Environment and Sustainable Technology Division, The University of Manchester, P.O. Box 88, Sackville St., Manchester M60 1QD, UK, reff.adam@epa.gov Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 40 EP - 47 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 39 IS - 1 SN - 0021-8502, 0021-8502 KW - Pollution Abstracts KW - Sulfates KW - Particulates KW - carbonyl compounds KW - Wind KW - British Isles KW - Ammonium KW - Aerosols KW - Nitrates KW - Physicochemical properties KW - Vegetation KW - case studies KW - Fourier transforms KW - Rural areas KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21021842?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Aerosol+Science&rft.atitle=Collection+of+ambient+particulate+matter+by+porous+vegetation+barriers%3A+Sampling+and+characterization+methods&rft.au=Tiwary%2C+Abhishek%3BReff%2C+Adam%3BColls%2C+Jeremy+J&rft.aulast=Tiwary&rft.aufirst=Abhishek&rft.date=2008-01-01&rft.volume=39&rft.issue=1&rft.spage=40&rft.isbn=&rft.btitle=&rft.title=Journal+of+Aerosol+Science&rft.issn=00218502&rft_id=info:doi/10.1016%2Fj.jaerosci.2007.09.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - British Isles; Particulates; Fourier transforms; Aerosols; Nitrates; Wind; Physicochemical properties; Sulfates; Vegetation; carbonyl compounds; Rural areas; case studies; Ammonium DO - http://dx.doi.org/10.1016/j.jaerosci.2007.09.011 ER - TY - JOUR T1 - Water quality trading in the United States: trading programs and one-time offset agreements AN - 21009563; 8045188 AB - This paper provides a systematic overview of water quality trading programs and one-time offset agreements in the USA. The primary source of information for this overview is a detailed database, collected and compiled by a team of researchers at Dartmouth College. Details discussed include: sources of the pollutant, types of pollutants traded, legal liability, main regulatory drivers, market structure, trading ratios, transaction and administrative costs and difficulties encountered in trading. We find that trading has often been explored as a way to meet more stringent discharge limits or watershed-wide caps. The most common type of trading program in the United States is between point sources and non-point sources. Point sources are usually held liable for non-point source reductions. The pollutants most commonly traded in the USA are nutrients such as phosphorus and nitrogen and almost all offset and trading programs focus on one pollutant only. However, market structures, trading ratios and other details of the trading framework vary widely among programs. No single characteristic appears to be a good predictor of a successful trading program. JF - Water Policy AU - Morgan, C AU - Wolverton, A AD - US EPA, National Center for Environmental Economics, 1200 Pennsylvania Av., NW, MC 1809T, Washington, DC, 20460, USA, morgan.cynthia@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 73 EP - 93 VL - 10 IS - 1 SN - 1366-7017, 1366-7017 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts KW - water policy KW - water quality KW - Water Quality KW - Nonpoint Pollution Sources KW - Phosphorus KW - Nutrients KW - Nonpoint pollution KW - Water quality KW - Liability KW - Education establishments KW - Water pollution KW - nutrients KW - Databases KW - USA KW - Education KW - Pollutants KW - Structure KW - Nitrogen KW - Water policy KW - Q5 08503:Characteristics, behavior and fate KW - M2 556.5:Surface Water Hydrology (556.5) KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - Q2 09184:Composition of water KW - SW 3020:Sources and fate of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21009563?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Policy&rft.atitle=Water+quality+trading+in+the+United+States%3A+trading+programs+and+one-time+offset+agreements&rft.au=Morgan%2C+C%3BWolverton%2C+A&rft.aulast=Morgan&rft.aufirst=C&rft.date=2008-01-01&rft.volume=10&rft.issue=1&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Water+Policy&rft.issn=13667017&rft_id=info:doi/10.2166%2Fwp.2007.028 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Liability; Water quality; Education establishments; Water pollution; Water policy; water policy; nutrients; water quality; Phosphorus; Nonpoint pollution; Nitrogen; Databases; Education; Pollutants; Structure; Nonpoint Pollution Sources; Water Quality; Nutrients; USA DO - http://dx.doi.org/10.2166/wp.2007.028 ER - TY - JOUR T1 - Assessment of caudal fin clip as a non-lethal technique for predicting muscle tissue mercury concentrations in largemouth bass AN - 20992572; 8366007 JF - Environmental Chemistry AU - Ryba, SA AU - Lake, J L AU - Serbst, J R AU - Libby, AD AU - Ayvazian, S AD - National Health and Environmental Effects Research Laboratory-Atlantic Ecology Division, Office of Research and Development, United States Environmental Protection Agency, 27 Tarzwell Dr., Narragansett, RI 02882, USA, ryba.stephan@epa.gov Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 200 EP - 203 PB - CSIRO Publishing, PO Box 1139 150 Oxford Street Collingwood Vic. 3066 Australia, [mailto:publishing@csiro.au] VL - 5 IS - 3 SN - 1448-2517, 1448-2517 KW - Largemouth bass KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - bioavailability KW - largemouth bass KW - mercury KW - metals KW - non KW - lethal methods KW - Tissues KW - Micropterus salmoides KW - Muscles KW - Pollution effects KW - Freshwater KW - Freshwater fish KW - Bioaccumulation KW - Analytical techniques KW - Mercury KW - P 2000:FRESHWATER POLLUTION KW - Q5 08504:Effects on organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20992572?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Chemistry&rft.atitle=Assessment+of+caudal+fin+clip+as+a+non-lethal+technique+for+predicting+muscle+tissue+mercury+concentrations+in+largemouth+bass&rft.au=Ryba%2C+SA%3BLake%2C+J+L%3BSerbst%2C+J+R%3BLibby%2C+AD%3BAyvazian%2C+S&rft.aulast=Ryba&rft.aufirst=SA&rft.date=2008-01-01&rft.volume=5&rft.issue=3&rft.spage=200&rft.isbn=&rft.btitle=&rft.title=Environmental+Chemistry&rft.issn=14482517&rft_id=info:doi/10.1071%2FEN08017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Analytical techniques; Muscles; Pollution effects; Mercury; Freshwater fish; Tissues; Bioaccumulation; Micropterus salmoides; Freshwater DO - http://dx.doi.org/10.1071/EN08017 ER - TY - JOUR T1 - Food of the Desert Eagle Owl, Bubo ascalaphus Savigny, 1809, in Siwa Oasis, Western Desert, Egypt AN - 20976944; 8572201 AB - The diet of the Desert Eagle Owl (Bubo ascalaphus Savigny, 1809) is poorly known compared to its European counterpart, the Eurasian Eagle Owl (Bubo bubo (Linnaeus, 1758)). Previous studies have concentrated on the western and north-western parts of its distribution (Morocco: Lesne & Thevenot 1981; Algeria: Boukhamza et al. 1994; Tunis: Alaya & NOUIRA 2007; Libya: Niethammer 1963) or on the eastern part, the Middle East (Syria: Shehab 2004; Saudi Arabia: Evans & Bates 1993; Jordan: Rifai et al. 2000). From Egypt, JAnossy & Schmidt (1970) have given some information on a few pellets collected at Saqqara, close to Cairo, Goodman (1986) has described the contents of a few putative Eagle Owl pellets from the Sinai Peninsula, and Goodman (1990) has analysed pellets from Kharga Oasis. JF - Zoology in the Middle East AU - Sandor, AD AU - Orban, Z AD - Environmental Protection Agency, str. Podeni 10, Targu Mures, 540253, Romania, adsandor@gmail.com Y1 - 2008 PY - 2008 DA - 2008 SP - 107 EP - 109 VL - 44 SN - 0939-7140, 0939-7140 KW - Ecology Abstracts KW - Diets KW - Deserts KW - Food KW - Bubo bubo KW - Bubo KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20976944?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zoology+in+the+Middle+East&rft.atitle=Food+of+the+Desert+Eagle+Owl%2C+Bubo+ascalaphus+Savigny%2C+1809%2C+in+Siwa+Oasis%2C+Western+Desert%2C+Egypt&rft.au=Sandor%2C+AD%3BOrban%2C+Z&rft.aulast=Sandor&rft.aufirst=AD&rft.date=2008-01-01&rft.volume=44&rft.issue=&rft.spage=107&rft.isbn=&rft.btitle=&rft.title=Zoology+in+the+Middle+East&rft.issn=09397140&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Bubo; Bubo bubo; Deserts; Diets; Food ER - TY - JOUR T1 - Front-loading Urban Stormwater Management for Success - A Perspective Incorporating Current Studies on the Implementation of Retrofit Low-impact Development AN - 20960126; 11054995 AB - Recent work into the implementation of low-impact development (LID) suggests that a decentralized, source-control approach has the potential to significantly reduce urban stormwater runoff quantity. The practice of retrofit stormwater management is currently dominated by demonstration projects, and some additional momentum is required to spur adoption and upscaling of LID practices so that the scale of this management approach can better match the scale of disturbance. This momentum may be provided in part by targeted research into effectiveness of stormwater best management practices insofar as research accounts for cost and effectiveness (e.g., water quality benefits, and actual stormwater capture) under a variety of climate conditions. We posit that the factors of increasing public participation in stormwater management; engaging local agencies and non-governmental organizations (NGOs); application of proven source control methods to mitigate runoff formation; and science-based, comprehensive monitoring strategies are all important to the sustainable implementation of retrofit low-impact development. From the perspective of Federal researchers and local NGOs, this paper presents features, objectives, and costs of recent efforts to properly scale demonstration projects and broader LID initiatives. JF - Cities and the Environment AU - Shuster, W D AU - Morrison, MA AU - Webb, R AD - US Environmental Protection Agency, USA Y1 - 2008 PY - 2008 DA - 2008 VL - 1 IS - 2 KW - Sustainability Science Abstracts KW - water quality KW - disturbance KW - nongovernmental organizations KW - Sustainable development KW - Public participation KW - best practices KW - Stormwater runoff KW - Urban areas KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20960126?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cities+and+the+Environment&rft.atitle=Front-loading+Urban+Stormwater+Management+for+Success+-+A+Perspective+Incorporating+Current+Studies+on+the+Implementation+of+Retrofit+Low-impact+Development&rft.au=Shuster%2C+W+D%3BMorrison%2C+MA%3BWebb%2C+R&rft.aulast=Shuster&rft.aufirst=W&rft.date=2008-01-01&rft.volume=1&rft.issue=2&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Cities+and+the+Environment&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - nongovernmental organizations; Public participation; Sustainable development; Urban areas; water quality; disturbance; best practices; Stormwater runoff ER - TY - JOUR T1 - Drinking water public right-to-know requirements in the United States AN - 20935893; 8208493 AB - The United States Environmental Protection Agency implements a national drinking-water program under the authority of the Federal Safe Drinking Water Act. Amendments to the Act in 1996 added new provisions to enhance consumer understanding of drinking-water issues. Notification requirements associated with annual consumer confidence reports, source water assessments and state compliance reports are intended to enhance the public's knowledge of the quality of their drinking water. Water utilities are also subject to public notification requirements to provide more timely information to consumers in response to violations of health standards. These right-to-know requirements are intended to build the public's confidence, but communicating with consumers can be challenging for both utility managers and government leaders. This paper discusses the need for timely communication, the challenge of providing information when there is uncertainty in the science and the importance of preparing to respond to critical incidents. Because surveys have shown that other members of the community may have better access to consumers or are more trusted, it is important for water utilities to establish relationships with the media and the local public health community. JF - Journal of Water and Health AU - Blette, V AD - Office of Ground Water and Drinking Water, United States Environmental Protection Agency, 1200 Pennsylvania Avenue, N.W., MC 4601M, Washington, DC 20460, USA, blette.veronica@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 43 EP - 52 VL - 6 SN - 1477-8920, 1477-8920 KW - Aqualine Abstracts; Water Resources Abstracts KW - Compliance KW - Surveys KW - Environmental Protection KW - Utilities KW - USA KW - Drinking Water KW - Public Health KW - Assessments KW - Water Requirements KW - Standards KW - AQ 00008:Effects of Pollution KW - SW 4050:Water law and institutions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20935893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+and+Health&rft.atitle=Drinking+water+public+right-to-know+requirements+in+the+United+States&rft.au=Blette%2C+V&rft.aulast=Blette&rft.aufirst=V&rft.date=2008-01-01&rft.volume=6&rft.issue=&rft.spage=43&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+and+Health&rft.issn=14778920&rft_id=info:doi/10.2166%2Fwh.2008.031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Public Health; Drinking Water; Assessments; Compliance; Surveys; Environmental Protection; Standards; Water Requirements; Utilities; USA DO - http://dx.doi.org/10.2166/wh.2008.031 ER - TY - JOUR T1 - Speciation and Localization of Arsenic in White and Brown Rice Grains AN - 20933988; 8125928 AB - Synchrotron-based X-ray fluorescence (S-XRF) was utilized to locate arsenic (As) in polished (white) and unpolished (brown) rice grains from the United States, China, and Bangladesh. In white rice As was generally dispersed throughout the grain, the bulk of which constitutes the endosperm. In brown rice As was found to be preferentially localized at the surface, in the region corresponding to the pericarp and aleurone layer. Copper, iron, manganese, and zinc localization followed that of arsenic in brown rice, while the location for cadmium and nickel was distinctly different, showing relatively even distribution throughout the endosperm. The localization of As in the outer grain of brown rice was confirmed by laser ablation ICP-MS. Arsenic speciation of all grains using spatially resolved X-ray absorption near edge structure ( mu -XANES) and bulk extraction followed by anion exchange HPLC-ICP-MS revealed the presence of mainly inorganic As and dimethylarsinic acid (DMA). However, the two techniques indicated different proportions of inorganic:organic As species. A wider survey of whole grain speciation of white (n = 39) and brown (n = 45) rice samples from numerous sources (field collected, supermarket survey, and pot trials) showed that brown rice had a higher proportion of inorganic arsenic present than white rice. Furthermore, the percentage of DMA present in the grain increased along with total grain arsenic. JF - Environmental Science & Technology AU - Feldmann, Joerg AU - Scheckel, Kirk G AU - Williams, Paul N AU - Raab, Andrea AU - Lombi, Enzo AU - Zhu, Yongguan AU - Islam, Rafiql AU - Meharg, Andrew A AD - School of Biological Sciences, University of Aberdeen, Cruickshank Boulevard, St Machar Drive, Aberdeen, AB24 3UU, U.K., Plant and Soil Science Laboratory, Department of Agricultural Science, Faculty of Life Science, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, 5995 Centre Hill Avenue, Cincinnati, Ohio 45224, School of Physical Sciences, University of Aberdeen, Meston Building, Meston Walk, Aberdeen, AB24 3UE, U.K., Research Centre for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 1051 EP - 1057 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 4 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Molecular structure KW - Arsenic KW - Fluorescence KW - Anions KW - Heavy metals KW - Nickel KW - Oryza sativa KW - Copper KW - Crops KW - USA KW - Absorption spectroscopy KW - Zinc KW - Absorption KW - China, People's Rep. KW - Iron KW - Manganese KW - Ion exchange KW - Bangladesh KW - Ablation KW - Q5 08503:Characteristics, behavior and fate KW - P 5000:LAND POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20933988?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Speciation+and+Localization+of+Arsenic+in+White+and+Brown+Rice+Grains&rft.au=Feldmann%2C+Joerg%3BScheckel%2C+Kirk+G%3BWilliams%2C+Paul+N%3BRaab%2C+Andrea%3BLombi%2C+Enzo%3BZhu%2C+Yongguan%3BIslam%2C+Rafiql%3BMeharg%2C+Andrew+A&rft.aulast=Feldmann&rft.aufirst=Joerg&rft.date=2008-01-01&rft.volume=42&rft.issue=4&rft.spage=1051&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes702212p LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Molecular structure; Absorption spectroscopy; Arsenic; Heavy metals; Nickel; Ion exchange; Ablation; Anions; Fluorescence; Zinc; Absorption; Copper; Manganese; Iron; Crops; Oryza sativa; USA; China, People's Rep.; Bangladesh DO - http://dx.doi.org/10.1021/es702212p ER - TY - JOUR T1 - Mercury Mass Budget Estimates and Cycling Seasonality in the Florida Everglades AN - 20931823; 8133668 AB - We estimated the mass budget for mercury (Hg) seasonally deposited into the Florida Everglades and investigated seasonality of Hg cycling by analyzing data obtained for water, soil, flocculent detrital material (floc), periphyton, and mosquitofish collected throughout the Everglades freshwater marshes in the 2005 dry and wet seasons. Higher wet season total Hg (THg) in soil, floc, and periphyton agreed with greater Hg amounts entering these compartments during the wet season, probably owing to substantially greater Hg deposition in the wet season than in the dry season. Seasonal differences were absent for THg in surface water. Methylmercury (MeHg) showed mixed seasonal patterns, with higher water and soil MeHg and lower periphyton MeHg in the dry season but no seasonality for floc MeHg. Seasonal variations in Hg deposition, MeHg production and transport, and mass of ecosystem compartments could be responsible for the seasonality of MeHg cycling. Higher mosquitofish THg, higher bioaccumulation factors, and higher biomagnification factors from periphyton to mosquitofish were observed in the wet season than in the dry season, indicating that the wet season is more favorable for Hg bioaccumulation. The mass budget estimation agreed with this result. JF - Environmental Science & Technology AU - Cai, Yong AU - Kalla, Peter AU - Gaiser, Evelyn AU - Liu, Guangliang AU - Appleby, Charlie AU - Scinto, Leonard J AU - Richards, Jennifer AU - Scheidt, Daniel AD - Department of Chemistry & Biochemistry, Florida International University, Miami, Florida 33199, Southeast Environmental Research Center, Florida International University, Miami, Florida 33199, Science and Ecosystem Support Division, U.S. Environmental Protection Agency, Region 4, Athens, Georgia 30605, Water Management Division, U.S. Environmental Protection Agency, Region 4, Athens, Georgia 30605 Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 1954 EP - 1960 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 6 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts KW - Seasonal Variations KW - Ecosystems KW - Surface water KW - Biological Magnification KW - Surface Water KW - Freshwater KW - Freshwater fish KW - Soil KW - Sulfur dioxide KW - Rainy season KW - Dimethylmercury KW - budgets KW - Seasonal variations KW - Seasonality KW - Methylmercury KW - Methyl mercury KW - USA, Florida, Everglades KW - Data processing KW - Freshwater environments KW - dry season KW - Marshes KW - Bioaccumulation KW - Deposition KW - Mercury KW - Periphyton KW - Dry season KW - Q5 08503:Characteristics, behavior and fate KW - P 2000:FRESHWATER POLLUTION KW - SW 3030:Effects of pollution KW - K 03450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20931823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Mercury+Mass+Budget+Estimates+and+Cycling+Seasonality+in+the+Florida+Everglades&rft.au=Cai%2C+Yong%3BKalla%2C+Peter%3BGaiser%2C+Evelyn%3BLiu%2C+Guangliang%3BAppleby%2C+Charlie%3BScinto%2C+Leonard+J%3BRichards%2C+Jennifer%3BScheidt%2C+Daniel&rft.aulast=Cai&rft.aufirst=Yong&rft.date=2008-01-01&rft.volume=42&rft.issue=6&rft.spage=1954&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes7022994 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Seasonality; Methyl mercury; Bioaccumulation; Rainy season; Mercury; Marshes; Periphyton; Dry season; Freshwater fish; Soil; Data processing; Surface water; Freshwater environments; Dimethylmercury; Seasonal variations; Methylmercury; Sulfur dioxide; dry season; budgets; Seasonal Variations; Ecosystems; Deposition; Biological Magnification; Surface Water; USA, Florida, Everglades; Freshwater DO - http://dx.doi.org/10.1021/es7022994 ER - TY - JOUR T1 - An Organotin Mixture Found in Polyvinyl Chloride (PVC) Pipe is not Immunotoxic to Adult Sprague-Dawley Rats AN - 20927674; 8024681 AB - Organotin compounds used in polyvinyl chloride (PVC) pipe production are of concern to the U.S. Environmental Protection Agency (EPA) because they leach from supply pipes into drinking water and are reported multisystem toxicants. Immune function was assessed in male Sprague-Dawley rats exposed to the mixture of organotins used in PVC pipe production. Although several of these organotins are reported immunotoxicants, their immuno-toxicity as a mixture when given by drinking water has not been evaluated. Adult male rats were given drinking water for 28 d containing a mixture of dibutyltin dichloride (DBTC), dimethyltin dichloride (DMTC), monobutyltin trichloride (MBT), and monomethyltin trichloride (MMT) in a 2:2:1:1 ratio, respectively, at 3 different concentrations (5:5:2.5:2.5, 10:10:5:5, or 20:20:10:10 mg organotin/L), MMT alone (20 or 40 mg MMT/L), or plain water as a control. Delayed-type hypersensitivity, antibody synthesis, and natural killer cell cytotoxicity were evaluated in separate endpoint groups (n = 8/dose; 24/endpoint) immediately after exposure ended. The evaluated immune functions were not affected by the mixture or by MMT alone. Our data suggest that immunotoxicity is unlikely to result from the concentration of organotins present in drinking water delivered via PVC pipes, as the concentrations used were several orders of magnitude higher than those expected to leach from PVC pipes. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - DeWitt, J C AU - Copeland, C B AU - Luebke, R W AD - U.S. Environmental Protection Agency, MDB143-01, 109 TW Alexander Drive, Research Triangle Park, NC 27711, USA, luebke.robert@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 276 EP - 282 VL - 71 IS - 3-4 SN - 1528-7394, 1528-7394 KW - Toxicology Abstracts; Immunology Abstracts KW - Dibutyltin KW - Organotin KW - Toxicants KW - Natural killer cells KW - polyvinyl chloride KW - Cytotoxicity KW - Antibodies KW - Immunotoxicity KW - Hypersensitivity (delayed) KW - MMT KW - Immune response KW - Monobutyltin KW - Drinking water KW - Organotin compounds KW - F 06955:Immunomodulation & Immunopharmacology KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20927674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=An+Organotin+Mixture+Found+in+Polyvinyl+Chloride+%28PVC%29+Pipe+is+not+Immunotoxic+to+Adult+Sprague-Dawley+Rats&rft.au=DeWitt%2C+J+C%3BCopeland%2C+C+B%3BLuebke%2C+R+W&rft.aulast=DeWitt&rft.aufirst=J&rft.date=2008-01-01&rft.volume=71&rft.issue=3-4&rft.spage=276&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390701613025 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Dibutyltin; Organotin; Toxicants; polyvinyl chloride; Natural killer cells; Immunotoxicity; Antibodies; Cytotoxicity; Hypersensitivity (delayed); MMT; Immune response; Drinking water; Monobutyltin; Organotin compounds DO - http://dx.doi.org/10.1080/15287390701613025 ER - TY - JOUR T1 - Simulating the vapour phase air/water exchange of p,p'-DDE, p,p'-DDT, lindane, and 2,3,7,8-tetrachlorodibenzodioxin AN - 20892514; 8399678 AB - Uncertainties in our understanding of gaseous air/water exchange have emerged as major sources of concern in efforts to construct global and regional mass balances of both the green house gas carbon dioxide and semi-volatile persistent, bioaccumulative and toxic chemicals. Hoff et al. (1996) suggested that these uncertainties result from a lack of understanding of the overall gaseous air/water mass transport process as well as imprecision in our ability to perform the necessary physicochemical property measurements of the gaseous species of interest. In this work, nine low to intermediate wind speed-dependent mass transport models were evaluated as to their suitability for simulating air/water gaseous exchange of 2,3,7,8-TCDD, p,p'-DDT, p,p'-DDE and lindane. In addition, two physicochemical property estimation procedures were examined over an environmental temperature range of 0 to 40 degree C and compared with observations reported elsewhere in the literature. Findings from the work included: (1) the gaseous air/water exchange paradigm published by Mackay and Yeun (1983) appears to be the most robust, (2) models derived from environmental SF sub(6) exchange data may generate upper limits for overall mass transfer coefficients but also may overestimate gaseous air/water exchange for compounds with small Henry's Law constants, and (3) neither the property estimation procedures outlined by Paasiverta et al. (1999) nor those by Hilal et al. (2003) are suitable for all physicochemical property estimates; instead, combinations of property estimation procedures from both may be most useful. JF - Chemical Speciation and Bioavailability AU - Loux, N T AD - US EPA/ORD/NERL/ERD, 960 College Station Road, Athens, GA 30605-2700, USA, loux.nick@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 77 EP - 92 VL - 20 IS - 2 SN - 0954-2299, 0954-2299 KW - Pollution Abstracts KW - Physicochemical properties KW - Temperature KW - mass transport KW - Lindane KW - Bioavailability KW - Bioaccumulation KW - Australia, Queensland, Mackay KW - Chemical speciation KW - Water wells KW - Air-water interactions KW - Carbon dioxide KW - water exchange KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20892514?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemical+Speciation+and+Bioavailability&rft.atitle=Simulating+the+vapour+phase+air%2Fwater+exchange+of+p%2Cp%27-DDE%2C+p%2Cp%27-DDT%2C+lindane%2C+and+2%2C3%2C7%2C8-tetrachlorodibenzodioxin&rft.au=Loux%2C+N+T&rft.aulast=Loux&rft.aufirst=N&rft.date=2008-01-01&rft.volume=20&rft.issue=2&rft.spage=77&rft.isbn=&rft.btitle=&rft.title=Chemical+Speciation+and+Bioavailability&rft.issn=09542299&rft_id=info:doi/10.3184%2F095422908X322842 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Australia, Queensland, Mackay; water exchange; Air-water interactions; Physicochemical properties; Lindane; mass transport; Carbon dioxide; Chemical speciation; Bioaccumulation; Temperature; Bioavailability; Water wells DO - http://dx.doi.org/10.3184/095422908X322842 ER - TY - JOUR T1 - Copper-Doped Silica Materials Silanized With Bis-(Triethoxy Silyl Propyl)-Tetra Sulfide for Mercury Vapor Capture AN - 20884956; 8378325 AB - The use of Cu-S sites for Hg capture from the gas phase has been successfully applied to a silica-based platform using an S4 organic polysulfane and copper sulfate. The maximum fixed-bed equilibrium capacity achieved using these materials was 19 789 kg Hg.g super(-1) sorbent for a material with 2.5 wt % Cu and 6 wt % S. An optimal S level was determined to be around 3 wt % because enhancement of capacity was only 18% when increasing from this 3 to 6 wt %. The rate of adsorption in pure beds ranged from 0.6 to 1.6 kg Hg.min super(-1) depending on the inlet concentration. Differences in breakthrough times suggest that material deposition is not uniform. When compared to two other platforms, commercially available Darco HG-LH and previously tested Fe-Cu-S4 nanoaggregates, the Si-1 material performed the best in fixed-bed testing. During entrained-flow testing, a steady-state Hg removal of 82% was achieved using Si-1 at injection rates of both 6 x 10 super(- 5) and 1.2 x 10 super(-4) g.L super(-1).h super(-1). The lack of increase in Hg removal when the injection rate is doubled suggests that pore accessibility is the rate-controlling step during dynamic Hg capture. A calculation of the approximate pore usage based on injection testing helped confirm this observation. During injection testing, the performance of Si-1 was only diminished 10% when exposed to 20 ppm SO sub(3). This is an encouraging result for flue-gas applications where SO sub(3) levels range from 1 to 40 ppm. Testing demonstrated that Si-1 is stable when exposed to leaching conditions after concrete blending and cement impregnation. This is an important aspect to consider for injection because the sale of fly ash for concrete is a key cost-recovery tool for power plants. JF - Energy & Fuels AU - Bhattacharyya, D AU - Hua, D AU - Meyer, DE AU - Hutson, N D AU - Meeks, N AU - Sikdar, S AD - Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky 40506, U.S. Environmental Protection Agency Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 2290 EP - 2298 PB - American Chemical Society, [mailto:service@acs.org] VL - 22 IS - 4 SN - 0887-0624, 0887-0624 KW - Pollution Abstracts KW - Leaching KW - Cement KW - Fuels KW - Sulfides KW - Fly ash KW - Concrete KW - Sorbents KW - Vapors KW - silica KW - Adsorption KW - Power plants KW - Mercury KW - copper sulfate KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20884956?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Energy+%26+Fuels&rft.atitle=Copper-Doped+Silica+Materials+Silanized+With+Bis-%28Triethoxy+Silyl+Propyl%29-Tetra+Sulfide+for+Mercury+Vapor+Capture&rft.au=Bhattacharyya%2C+D%3BHua%2C+D%3BMeyer%2C+DE%3BHutson%2C+N+D%3BMeeks%2C+N%3BSikdar%2C+S&rft.aulast=Bhattacharyya&rft.aufirst=D&rft.date=2008-01-01&rft.volume=22&rft.issue=4&rft.spage=2290&rft.isbn=&rft.btitle=&rft.title=Energy+%26+Fuels&rft.issn=08870624&rft_id=info:doi/10.1021%2Fef8001873 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Leaching; Cement; Fuels; Sulfides; Fly ash; Concrete; Vapors; Sorbents; silica; Power plants; Adsorption; Mercury; copper sulfate DO - http://dx.doi.org/10.1021/ef8001873 ER - TY - JOUR T1 - Source Apportionment and Spatial Distributions of Coarse Particles During the Regional Air Pollution Study AN - 20820514; 8220699 AB - To identify the coarse particle sources and to estimate the variability in their contributions to coarse particle mass (CPM) concentrations across the St. Louis metropolitan area, positive matrix factorization (PMF) was applied to historic ambient coarse particle compositional data from 10 Regional Air Pollution Study/Regional Air Monitoring System (RAPS/RAMS) monitoring sites in St. Louis. Coarse particles in this study had aerodynamic sizes between 2.4 and 20 km. The sources were qualitatively identified, and the source contributions were quantitatively estimated. Nine sources were identified for 8 of the 10 sampling sites (except rural sites 122 and 124) including soil, cement kiln/quarry, iron and steel, motor vehicle, incinerator, pigment plant, primary/secondary lead smelter, zinc smelter, and copper production, respectively. At site 122, five sources were identified as soil, cement kiln/quarry, motor vehicle, incinerator, and zinc smelter. At site 124, six sources were identified as soil, cement kiln/quarry, motor vehicle, incinerator, primary/secondary lead smelter, and zinc smelter. Soil was the largest coarse particle source across the study area (6.15 kg/m super(3), 29.3%). Cement kiln/quarry, iron and steel, and motor vehicle sources were the other large contributions to the coarse particles mass (5.27 kg/m super(3), 25.1%; 3.53 kg/m super(3), 16.8%; 2.72 kg/m super(3), 12.9%). The results of this study suggest there can be significant potential for exposure misclassification in time-series epidemiologic studies when regressing health outcomes against source contributions if they were to be estimated at a single central monitoring site. JF - Environmental Science & Technology AU - Pinto, Joseph P AU - Hopke, Philip K AU - Hwang, Injo AD - Department of Chemical and Biomolecular Engineering, Clarkson University, Potsdam, New York 13699-5708 and U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711 Y1 - 2008 PY - 2008 DA - 2008 SP - 3524 EP - 3530 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 10 SN - 0013-936X, 0013-936X KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Atmospheric pollution variations KW - Atmospheric pollution KW - Quarrying KW - Spatial distribution KW - Atmospheric pollution monitoring KW - Motor vehicles KW - Environmental sciences KW - Particulates KW - Atmospheric pollution data KW - Smelters KW - Atmospheric pollution by motor vehicles KW - Lead KW - Air pollution KW - Soil KW - Zinc KW - Incinerators KW - Steel KW - Mining KW - Iron KW - Rural areas KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20820514?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Source+Apportionment+and+Spatial+Distributions+of+Coarse+Particles+During+the+Regional+Air+Pollution+Study&rft.au=Pinto%2C+Joseph+P%3BHopke%2C+Philip+K%3BHwang%2C+Injo&rft.aulast=Pinto&rft.aufirst=Joseph&rft.date=2008-01-01&rft.volume=42&rft.issue=10&rft.spage=3524&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes0716204 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution variations; Atmospheric pollution; Atmospheric pollution monitoring; Spatial distribution; Environmental sciences; Atmospheric pollution data; Atmospheric pollution by motor vehicles; Quarrying; Motor vehicles; Particulates; Smelters; Lead; Soil; Air pollution; Zinc; Incinerators; Mining; Steel; Iron; Rural areas DO - http://dx.doi.org/10.1021/es0716204 ER - TY - JOUR T1 - Invasion of the Upper Mississippi River system by saltwater amphipods AN - 20819949; 10978942 AB - Zoobenthic surveys of the large rivers of the Upper Mississippi River basin (Missouri, Upper Mississippi, and Ohio Rivers) in 2004-2006 revealed new invasions by euryhaline amphipods. The gammarid amphipods Echinogammarus ischnus and Gammantis tigrinus were discovered in the Ohio and Upper Mississippi Rivers in 2004. The corophiid amphipod Apocorophium lacustre was first found in the Ohio River in 1996, and first detected in the Upper Mississippi River in 2005. None of these invaders was collected in the Missouri River. The presence of breeding adults of all three species suggests they are permanently established in the Ohio and Upper Mississippi. The range and occurrence of all three species increased in the basin from 2004 through 2006. The contribution of the three invaders to total amphipod catch in the Upper Mississippi River increased from 23 % in 2005 and 2006. The establishment of nonindigenous amphipods will likely contribute to alterations of food webs and native faunal diversity in the invaded rivers. JF - Fundamental and Applied Limnology/Archiv fuer Hydrobiologie AU - Angradi, T R AU - Emery, E B AU - Wooten AD - United States Environmental Protection Agency; Office of Research and Development; National Health and Environmental Effects Research Laboratory; Mid-Continent Ecology Division, 6201 Congdon Boulevard; Duluth; MN USA, angradi.theodore@epa.gov A2 - Grigorovich, IA (ed) Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 67 EP - 77 VL - 173 IS - 1 SN - 1863-9135, 1863-9135 KW - Water Resources Abstracts; Aqualine Abstracts; ASFA 1: Biological Sciences & Living Resources KW - River Basins KW - River Systems KW - Ecological distribution KW - Limnology KW - USA, , Ohio R. KW - Freshwater KW - Food Chains KW - Gammarus tigrinus KW - Biological collections KW - Substrate preferences KW - USA, Missouri KW - Rivers KW - USA, Missouri R. KW - Apocorophium lacustre KW - Amphipods KW - Surveys KW - USA, Mississippi R. basin KW - North America, Mississippi R. KW - USA, Kentucky, Ohio R. KW - USA, Mississippi R KW - Echinogammarus ischnuss KW - Introduced species KW - Zoobenthos KW - AQ 00001:Water Resources and Supplies KW - Q1 08462:Benthos KW - SW 0835:Streamflow and runoff UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20819949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fundamental+and+Applied+Limnology%2FArchiv+fuer+Hydrobiologie&rft.atitle=Invasion+of+the+Upper+Mississippi+River+system+by+saltwater+amphipods&rft.au=Angradi%2C+T+R%3BEmery%2C+E+B%3BWooten&rft.aulast=Angradi&rft.aufirst=T&rft.date=2008-01-01&rft.volume=173&rft.issue=1&rft.spage=67&rft.isbn=&rft.btitle=&rft.title=Fundamental+and+Applied+Limnology%2FArchiv+fuer+Hydrobiologie&rft.issn=18639135&rft_id=info:doi/10.1127%2F1863-9135%2F2008%2F0173-0067 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-10-01 N1 - SuppNotes - Physical medium: Printed matter N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Substrate preferences; Biological collections; Ecological distribution; Zoobenthos; Introduced species; Rivers; Food Chains; River Basins; River Systems; Amphipods; Surveys; Limnology; Gammarus tigrinus; Apocorophium lacustre; Echinogammarus ischnuss; USA, Missouri R.; North America, Mississippi R.; USA, Missouri; USA, Kentucky, Ohio R.; USA, , Ohio R.; USA, Mississippi R; USA, Mississippi R. basin; Freshwater DO - http://dx.doi.org/10.1127/1863-9135/2008/0173-0067 ER - TY - JOUR T1 - Digital image analysis of Zostera marina leaf injury AN - 20812749; 8182141 AB - Current methods for assessing leaf injury in Zostera marina (eelgrass) utilize subjective indexes for desiccation injury and wasting disease. Because of the subjective nature of these measures, they are inherently imprecise making them difficult to use in quantifying complex leaf injuries from multiple sources. We have developed a method using color digital photography of eelgrass leaves which are then manipulated using image processing programs and analyzed using geographic digital image analysis. The resulting false color images are then assigned by the user into uninjured and injured groupings which may then be reported as a percentage of leaf area affected. If images are rectified, leaf area (cm super(2)) of injured and uninjured leaf segments may be determined. Although this method is time consuming and still requires some subjective judgments, it does allow for precise analysis of highly complex leaf injuries and has the potential to be a substantial improvement over existing leaf injury indexes. JF - Aquatic Botany AU - Boese, B L AU - Clinton, P J AU - Dennis, D AU - Golden, R C AU - Kim, B AD - Pacific Coastal Ecology Branch, 2111 SE Marine Science Drive, Newport, OR 97365, USA, boese.bruce@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 87 EP - 90 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 88 IS - 1 SN - 0304-3770, 0304-3770 KW - ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; Water Resources Abstracts; Ecology Abstracts KW - Marine KW - Leaf area KW - Injuries KW - Marinas KW - Leaves KW - Drying KW - Image processing KW - Color KW - Marine plants (see also marine algae, seaweeds) KW - Sea grass KW - Diseases KW - Desiccation KW - Zostera marina KW - Photography KW - O 1070:Ecology/Community Studies KW - Q1 08226:Physiology, biochemistry, biophysics KW - SW 0810:General KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20812749?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Botany&rft.atitle=Digital+image+analysis+of+Zostera+marina+leaf+injury&rft.au=Boese%2C+B+L%3BClinton%2C+P+J%3BDennis%2C+D%3BGolden%2C+R+C%3BKim%2C+B&rft.aulast=Boese&rft.aufirst=B&rft.date=2008-01-01&rft.volume=88&rft.issue=1&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Aquatic+Botany&rft.issn=03043770&rft_id=info:doi/10.1016%2Fj.aquabot.2007.08.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Injuries; Leaves; Image processing; Sea grass; Desiccation; Photography; Leaf area; Color; Marine plants (see also marine algae, seaweeds); Marinas; Drying; Diseases; Zostera marina; Marine DO - http://dx.doi.org/10.1016/j.aquabot.2007.08.016 ER - TY - JOUR T1 - Overview: Workshop on Children's Inhalation Dosimetry and Health Effects for Risk Assessment AN - 20735509; 8024670 AB - There has been increased emphasis and effort in recent years to expand the scope of human health risk assessments to more specifically include consideration of children's environmental health (NRC, 1993; EO, 1997; U.S. EPA, 1995, 2006a). It is important to consider children's risk because children may experience adverse health effects that are different from adults, in terms of both the nature of the effect and the dose-response relationship, due to growth and development, and the concomitant cellular proliferation and differentiation, which continue through puberty (Selevan et al., 2000). Children may also experience different exposures to environmental hazards due to unique, child-specific behaviors, such as breast feeding, crawling, playing outdoors, and consuming oxygen and nutrients at rates needed by a growing organism (U.S. EPA, 2006b). JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Foos, B AU - Sonawane, B AD - U.S. Environmental Protection Agency, Office of Children's Health Protection and Environmental Education, 1200 Pennsylvania Ave., NW, MC 1107A, Washington, DC 20460, USA, foos.brenda@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 147 EP - 148 VL - 71 IS - 3-4 SN - 1528-7394, 1528-7394 KW - Health & Safety Science Abstracts; Risk Abstracts; Toxicology Abstracts KW - breast feeding KW - Risk assessment KW - Inhalation KW - Environmental health KW - Nutrients KW - environmental hazards KW - Differentiation KW - Dose-response effects KW - Breast feeding KW - Conferences KW - Dosimetry KW - Children KW - nutrients KW - EPA KW - Oxygen KW - USA KW - Reviews KW - Puberty KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20735509?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Overview%3A+Workshop+on+Children%27s+Inhalation+Dosimetry+and+Health+Effects+for+Risk+Assessment&rft.au=Foos%2C+B%3BSonawane%2C+B&rft.aulast=Foos&rft.aufirst=B&rft.date=2008-01-01&rft.volume=71&rft.issue=3-4&rft.spage=147&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390701597855 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Inhalation; Risk assessment; Oxygen; Differentiation; Conferences; Dose-response effects; Reviews; Dosimetry; Nutrients; Breast feeding; Children; Puberty; nutrients; breast feeding; EPA; Environmental health; environmental hazards; USA DO - http://dx.doi.org/10.1080/15287390701597855 ER - TY - JOUR T1 - Evaluation of the physical stability, groundwater seepage control, and faunal changes associated with an AquaBlok(r) sediment cap AN - 20733222; 8904018 AB - Active sediment caps are being considered for addressing contaminated sediment areas in surface-water bodies. A demonstration of an active cap designed to reduce advective transport of contaminants using AquaBlok(r) (active cap material) was initiated in a small study area of the Anacostia River in Washington, D.C. The cap remained physically stable, demonstrated the ability to divert groundwater flow, and was recolonized with native organisms after 30 months of monitoring following cap placement. However, the long-term performance of active caps associated with harsh environmental conditions, hydrogeological settings, and subsurface gas production needs to be further evaluated. JF - Remediation AU - Barth, Edwin F AU - Reible, Danny AU - Bullard, Andrew AD - US EPA's Office of Research and Development, Cincinnati, Ohio Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 63 EP - 70 PB - John Wiley & Sons, 111 River Street Hoboken NJ 07030 USA, [mailto:custserv@wiley.com] VL - 18 IS - 4 SN - 1051-5658, 1051-5658 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Pollution Abstracts KW - Sediment pollution KW - Pollution monitoring KW - Seepage Control KW - Bioremediation KW - Surface water KW - Pollution dispersion KW - Sediments KW - Evaluation KW - USA, Washington KW - Performance Evaluation KW - Pollutants KW - Remediation KW - Ground water KW - Sediment Contamination KW - seepages KW - Groundwater KW - Monitoring KW - Environmental conditions KW - Groundwater Movement KW - USA, Washington D.C., Anacostia R. KW - Pollution control KW - Q5 08503:Characteristics, behavior and fate KW - SW 3010:Identification of pollutants KW - P 2000:FRESHWATER POLLUTION KW - Q2 09183:Physics and chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20733222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Remediation&rft.atitle=Evaluation+of+the+physical+stability%2C+groundwater+seepage+control%2C+and+faunal+changes+associated+with+an+AquaBlok%28r%29+sediment+cap&rft.au=Barth%2C+Edwin+F%3BReible%2C+Danny%3BBullard%2C+Andrew&rft.aulast=Barth&rft.aufirst=Edwin&rft.date=2008-01-01&rft.volume=18&rft.issue=4&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=Remediation&rft.issn=10515658&rft_id=info:doi/10.1002%2Frem.20183 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Pollution monitoring; Sediment pollution; Pollution dispersion; Ground water; Sediments; Pollution control; Bioremediation; Surface water; seepages; Environmental conditions; Evaluation; Performance Evaluation; Seepage Control; Pollutants; Remediation; Sediment Contamination; Monitoring; Groundwater; Groundwater Movement; USA, Washington; USA, Washington D.C., Anacostia R. DO - http://dx.doi.org/10.1002/rem.20183 ER - TY - JOUR T1 - Disinfection Processes and Stability Refinements to Biosolids Treatment Technologies AN - 20730271; 8173877 AB - This paper reviews the current United States sewage sludge disinfection regulations and their associated practices; discusses the limitations of the practices; the criteria employed in evaluating a new (innovative or alternative) disinfection process, and notes both some processes recently evaluated and ones evaluated. The United States regulations are designed to protect human health by minimizing the contact of humans with pathogenic microorganisms. Two types of disinfection processes are employed. Processes like pasteurization are employed to reduce pathogens below their analytical detection limits, while processes like anaerobic digestion are combined with requirements for organic matter reduction and access restrictions. Issues with the present disinfection alternatives such as their only being concerned with the presence or absence of certain pathogens like enteric viruses or Ascaris sp. are discussed and remedies suggested. Similarly, several of the current options for measuring vector attractiveness (stability) such as volatile solids reduction are in need of improvement. Work is underway to evaluate bacterial enzymatic activity and biochemical oxygen demand as possible measures of vector attractiveness. Innovative and alternative methods for disinfection are frequently proposed and it is important to understand how the stressors employed by the process contribute to its reduction of pathogenic bacteria, viruses, protozoa, and parasites. For example with an alkaline disinfection process it may be possible to utilize the beneficial effects of time, temperature, pH, chemical agents like ammonia, and pressure. A two-phase and batch thermophilic anaerobic digestion system, however, is able to utilize the benefits of high temperature, high levels of volatile fatty acids, and free ammonia to accomplish a large reduction of pathogens. Vermicomposting and a process that uses a fumigant are currently under evaluation by the U.S. Environmental Protection Agency and briefly discussed. JF - Practice Periodical of Hazardous, Toxic, and Radioactive Waste Management AU - Smith, JE Jr AU - Surampalli, R Y AU - Reimers, R S AU - Tyagi, R D AU - Lohani, B N AD - U.S. Environmental Protection Agency, P.O. Box 172141, Kansas City, KS 66117, USA, surampalli.rao@epa.gov Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 10 EP - 17 VL - 12 IS - 1 SN - 1090-025X, 1090-025X KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Aqualine Abstracts KW - Ammonia KW - Ascaris KW - Disinfection KW - USA KW - A 01450:Environmental Pollution & Waste Treatment KW - K 03400:Human Diseases KW - J 02320:Cell Biology KW - AQ 00008:Effects of Pollution KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20730271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Practice+Periodical+of+Hazardous%2C+Toxic%2C+and+Radioactive+Waste+Management&rft.atitle=Disinfection+Processes+and+Stability+Refinements+to+Biosolids+Treatment+Technologies&rft.au=Smith%2C+JE+Jr%3BSurampalli%2C+R+Y%3BReimers%2C+R+S%3BTyagi%2C+R+D%3BLohani%2C+B+N&rft.aulast=Smith&rft.aufirst=JE&rft.date=2008-01-01&rft.volume=12&rft.issue=1&rft.spage=10&rft.isbn=&rft.btitle=&rft.title=Practice+Periodical+of+Hazardous%2C+Toxic%2C+and+Radioactive+Waste+Management&rft.issn=1090025X&rft_id=info:doi/10.1061%2F%28ASCE%291090-025X%282008%2912%3A1%2810%29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Disinfection; Ascaris; USA DO - http://dx.doi.org/10.1061/(ASCE)1090-025X(2008)12:1(10) ER - TY - JOUR T1 - Effects of spatial extent on landscape structure and sediment metal concentration relationships in small estuarine systems of the United States' Mid-Atlantic Coast AN - 20727540; 8148196 AB - Prior studies exploring the quantitative relationship between landscape structure metrics and the ecological condition of receiving waters have used a variety of sampling units (e.g., a watershed, or a buffer around a sampling station) at a variety of spatial scales to generate landscape metrics resulting in little consensus on which scales best describe land-water relationships. Additionally, the majority of these studies have focused on freshwater systems and it is not clear whether results are transferable to estuarine and marine systems. We examined how sampling unit scale controls the relationship between landscape structure and sediment metal concentrations in small estuarine systems in the Mid-Atlantic region of the United States. We varied the spatial extent of the contributing watersheds used to calculate landscape structure and assessed linear relationships between estuarine sediment metal concentrations and the total area of developed and agricultural lands at each scale. Area of developed lands was consistently related to sediment metals while total agricultural land was not. Developed land had strongest associations with lead and copper; weakest with arsenic and chromium; and moderate associations with cadmium, mercury, and zinc. Local (i.e., less than 15-20 km from a sampling station) land uses have a greater impact than more distant land uses on the amount of toxic metals reaching estuarine sediments. JF - Landscape Ecology AU - Hollister, Jeffrey W AU - August, Peter V AU - Paul, John F AD - Office of Research and Development, US Environmental Protection Agency, 27 Tarzwell Drive, Narragansett, RI, 02882, USA, Hollister.Jeff@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 91 EP - 106 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de] VL - 23 SN - 0921-2973, 0921-2973 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources; Sustainability Science Abstracts; Ecology Abstracts KW - Arsenic KW - Heavy metals KW - Landscape KW - Brackish KW - Pollution effects KW - Estuarine sedimentation KW - Watersheds KW - Sediments KW - Lead KW - Land use KW - Agricultural land KW - Mercury KW - ANW, USA, Mid-Atlantic Region KW - Sampling KW - Q5 08503:Characteristics, behavior and fate KW - Q2 09264:Sediments and sedimentation KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20727540?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Landscape+Ecology&rft.atitle=Effects+of+spatial+extent+on+landscape+structure+and+sediment+metal+concentration+relationships+in+small+estuarine+systems+of+the+United+States%27+Mid-Atlantic+Coast&rft.au=Hollister%2C+Jeffrey+W%3BAugust%2C+Peter+V%3BPaul%2C+John+F&rft.aulast=Hollister&rft.aufirst=Jeffrey&rft.date=2008-01-01&rft.volume=23&rft.issue=&rft.spage=91&rft.isbn=&rft.btitle=&rft.title=Landscape+Ecology&rft.issn=09212973&rft_id=info:doi/10.1007%2Fs10980-007-9143-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Arsenic; Heavy metals; Mercury; Pollution effects; Estuarine sedimentation; Watersheds; Land use; Agricultural land; Landscape; Sampling; Lead; Sediments; ANW, USA, Mid-Atlantic Region; Brackish DO - http://dx.doi.org/10.1007/s10980-007-9143-1 ER - TY - JOUR T1 - Selecting and Evaluating Native Plants for Region-Specific Phytotoxicity Testing AN - 20627963; 8031529 AB - In this study, we evaluated methodology to determine risks to terrestrial native plant species from potential herbicide drift, focusing on 1) selection of native species for testing, 2) growth of these species, and 3) variability in herbicide response among native species and compared with crop plants. Native plant species were selected for initial testing on the basis of spatial analysis, which indicated that species from Illinois, USA, were at potential risk for off-target effects of herbicide drift. On the basis of preliminary seed germination tests, 5 native plant species (Andropogon gerardi, Polygonum lapathifolium, Solidago canadensis, Symphyotrichum lateriflorum, and Tridens flavus) were selected for comparison with crops grown in Illinois, normally used in the US Environmental Protection Agency's (USEPA's) Vegetative Vigor Test (Avena sativa, Daucus carota, Glycine max, Solanum lycopersicon, and Zea mays), or both. When treated with low concentrations of a test herbicide, sulfometuron methyl, 2 native species, P. lapathifolium and S. canadensis, were as sensitive as the 5 crop species. The effective herbicide concentrations producing a 25% reduction in shoot dry weight (EC25) for these species, ranged from 0.00015 to 0.0014 times a field application concentration of 52 g/ha active ingredient of sulfometuron methyl. S. lateriflorum and T. flavus were less sensitive than the other native species, whereas A. gerardi was tolerant to sulfometuron methyl with no growth reduction at any herbicide concentration tested. This study indicated that native species can be successfully selected and grown, used in the suite of species used in the USEPA's phytotoxicity test to assess risks of chemical herbicides to nontarget plants. It also showed (with a limited number of species) that native species varied more in sensitivity to simulated herbicide drift than crop species often used in phytotoxicity testing and that a Weibull function was useful to calculate EC25 values when low concentrations of herbicides was used. JF - Integrated Environmental Assessment and Management AU - Olszyk, David AU - Pfleeger, Thomas AU - Lee, EHenry AU - Burdick, Connie AU - King, George AU - Plocher, Milton AU - Kern, Jeffrey AD - US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Western Ecology Division, 200 SW 35th Street, Corvallis, Oregon 97333, olszyk.david@epa.gov Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 105 EP - 117 PB - Society of Environmental Toxicology and Chemistry (SETAC), 1010 North 12th Avenue Pensacola FL 32501-3367 USA, [mailto:setac@setac.org], [URL:http://www.setac.org] VL - 4 IS - 1 SN - 1551-3777, 1551-3777 KW - Pollution Abstracts; Ecology Abstracts KW - Herbicide KW - Sulfometuron methyl KW - Risk assessment KW - Lycopersicon KW - Andropogon KW - Plant protection KW - Polygonum lapathifolium KW - Solanum KW - Glycine max KW - Crops KW - Zea mays KW - Tridens flavus KW - Seed germination KW - shoots KW - Cadmium KW - spatial analysis KW - USA, Illinois KW - seed germination KW - Herbicides KW - Daucus carota KW - Solidago canadensis KW - Shoots KW - EPA KW - Indigenous species KW - Drift KW - Avena sativa KW - Phytotoxicity KW - P 6000:TOXICOLOGY AND HEALTH KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20627963?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Integrated+Environmental+Assessment+and+Management&rft.atitle=Selecting+and+Evaluating+Native+Plants+for+Region-Specific+Phytotoxicity+Testing&rft.au=Olszyk%2C+David%3BPfleeger%2C+Thomas%3BLee%2C+EHenry%3BBurdick%2C+Connie%3BKing%2C+George%3BPlocher%2C+Milton%3BKern%2C+Jeffrey&rft.aulast=Olszyk&rft.aufirst=David&rft.date=2008-01-01&rft.volume=4&rft.issue=1&rft.spage=105&rft.isbn=&rft.btitle=&rft.title=Integrated+Environmental+Assessment+and+Management&rft.issn=15513777&rft_id=info:doi/10.1897%2FIEAM_2007-044.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Shoots; Indigenous species; Plant protection; Drift; Seed germination; Phytotoxicity; Herbicides; Crops; spatial analysis; EPA; seed germination; shoots; Cadmium; Lycopersicon; Zea mays; Andropogon; Tridens flavus; Polygonum lapathifolium; Avena sativa; Solanum; Daucus carota; Solidago canadensis; Glycine max; USA, Illinois DO - http://dx.doi.org/10.1897/IEAM_2007-044.1 ER - TY - JOUR T1 - Examination of Arsenic Speciation in Sulfidic Solutions Using X-ray Absorption Spectroscopy AN - 20601457; 8107584 AB - Both thioarsenites and thioarsenates have been demonstrated to exist in sulfidic waters, yet there is uncertainty regarding the geochemical conditions that govern the formation of these arsenic species. The purpose of this research was to use advanced spectroscopy techniques, speciation modeling, and chromatography to elucidate the chemical speciation of arsenic in sulfidic solutions initially containing arsenite and sulfide. Results of X-ray absorption spectroscopy (XAS) show that experimental solutions contained mixtures of arsenite and thioarsenites with increasing substitution of sulfur for oxygen on arsenic as the sulfide concentration increased. Experimental samples showed no evidence of polymeric arsenic species, or transformation of thioarsenites to thioarsenates. The arsenic speciation measured using XAS was similar to predictions obtained from a thermodynamic model for arsenic speciation, excluding thioarsenate species in sulfidic systems. Our data cast some doubt on the application of chromatographic methods for determining thioarsenates and thioarsenites (or mixtures) in natural waters in cases where the arsenic oxidation state cannot be independently verified. The same chromatographic peak positions proposed for thioarsenates can be explained by thioarsenite species. Furthermore, sample dilution was shown to change the species distribution and care should be taken to avoid sample dilution prior to chromatographic analysis. JF - Environmental Science & Technology AU - Wilkin, Richard T AU - Ford, Robert G AU - Beak, Douglas G AU - Kelly, Shelly D AD - National Risk Management Research Laboratory, U.S. Environmental Protection Agency, 919 Kerr Research Drive, Ada, Oklahoma 74820 Y1 - 2008 PY - 2008 DA - 2008 SP - 1643 EP - 1650 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 5 SN - 0013-936X, 0013-936X KW - Pollution Abstracts KW - Sulfur KW - Arsenic KW - Thermodynamics KW - Chromatography KW - Sulfides KW - Geochemistry KW - Spectroscopy KW - Oxygen KW - Absorption spectroscopy KW - Chemical speciation KW - Oxidation KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20601457?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Examination+of+Arsenic+Speciation+in+Sulfidic+Solutions+Using+X-ray+Absorption+Spectroscopy&rft.au=Wilkin%2C+Richard+T%3BFord%2C+Robert+G%3BBeak%2C+Douglas+G%3BKelly%2C+Shelly+D&rft.aulast=Wilkin&rft.aufirst=Richard&rft.date=2008-01-01&rft.volume=42&rft.issue=5&rft.spage=1643&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes071858s LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Sulfur; Oxygen; Absorption spectroscopy; Arsenic; Thermodynamics; Chromatography; Chemical speciation; Oxidation; Geochemistry; Sulfides; Spectroscopy DO - http://dx.doi.org/10.1021/es071858s ER - TY - JOUR T1 - Technical Challenges Involved in Implementation of VOC Reactivity-Based Control of Ozone AN - 20601378; 8107580 AB - Controlling VOC emissions on the basis of their individual contribution to ozone formation has been subject to extensive discussion and research in past years, and the concept has gained some acceptance in the air pollution community for certain product categories and industrial operations. Despite its potential to decrease ozone formation, there are some technical challenges that still remain before we can confidently apply the concept of reactivity in the most beneficial manner to reduce ozone concentrations. The goal of this paper is to (1) assess how existing science in this area supports the use of reactivity, particularly, the maximum incremental reactivity, for VOC control under a national policy application and (2) identify where uncertainties exist that could affect such a policy. Box model and air quality model results are used to show that there are ways to describe a chemical's reactivity that are relatively robust across large geographic areas. Modeling results also indicate that the choice of metric is important in determining the potential benefits and detriments of a reactivity-based emission control policy. JF - Environmental Science & Technology AU - Mebust, M R AU - Luecken, D J AD - U.S. Environmental Protection Agency, MD E243-03, Research Triangle Park, North Carolina 27709 Y1 - 2008 PY - 2008 DA - 2008 SP - 1615 EP - 1622 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 5 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; Sustainability Science Abstracts KW - Air quality KW - Air pollution control KW - Emission control KW - Air pollution KW - Emissions KW - Volatile organic compounds KW - Ozone KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20601378?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Technical+Challenges+Involved+in+Implementation+of+VOC+Reactivity-Based+Control+of+Ozone&rft.au=Mebust%2C+M+R%3BLuecken%2C+D+J&rft.aulast=Mebust&rft.aufirst=M&rft.date=2008-01-01&rft.volume=42&rft.issue=5&rft.spage=1615&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes071036v LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Air pollution; Emissions; Emission control; Air pollution control; Air quality; Volatile organic compounds; Ozone DO - http://dx.doi.org/10.1021/es071036v ER - TY - JOUR T1 - Impact of an Updated Carbon Bond Mechanism on Predictions from the CMAQ Modeling System: Preliminary Assessment AN - 20597921; 8106668 AB - An updated and expanded version of the Carbon Bond mechanism (CB05) has been incorporated into the Community Multiscale Air Quality (CMAQ) modeling system to more accurately simulate wintertime, pristine, and high-altitude situations. The CB05 mechanism has nearly 2 times the number of reactions relative to the previous version of the Carbon Bond mechanism (CB-IV). While the expansions do provide more detailed treatment of urban areas, most of the new reactions involve biogenics, toxics, and species potentially important to particulate formation and acid deposition. Model simulations were performed using the CB05 and the CB-IV mechanisms for the winter and summer of 2001. For winter with the CB05 mechanism, ozone, aerosol nitrate, and aerosol sulfate concentrations were within 1% of the results obtained with the CB-IV mechanism. Organic carbon concentrations were within 2% of the results obtained with the CB-IV mechanism. However, formaldehyde and hydrogen peroxide concentrations were lower by 25% and 32%, respectively, during winter with the CB05 mechanism. For the summer, ozone concentrations increased by 8% with the CB05 mechanism relative to the CB-IV mechanism. The aerosol sulfate, aerosol nitrate, and organic carbon concentrations with the CB05 mechanism decreased by 8%, 2%, and 10%, respectively. The formaldehyde and hydrogen peroxide concentrations with the CB05 mechanism were lower by 12% and 47%, respectively, during summer. Model performance with the CB05 mechanism improved at high-altitude conditions and in rural areas for ozone. Model performance also improved for organic carbon with the CB05 mechanism. JF - Journal of Applied Meteorology and Climatology AU - Sarwar, G AU - Luecken, D AU - Yarwood, G AU - Whitten, G Z AU - Carter, WPL AD - Atmospheric Modeling Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, sarwargolam@epa.gov Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 3 EP - 14 PB - American Meteorological Society, 45 Beacon St. Boston MA 02108-3693 USA VL - 47 IS - 1 SN - 1558-8424, 1558-8424 KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Pollution Abstracts; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts KW - Sulfates KW - Organic carbon KW - Formaldehyde KW - Air quality KW - Particulate matter in urban air KW - Hydrogen KW - Carbon KW - Ozone concentration KW - Climatology KW - Urban areas KW - Ozone KW - Modelling KW - Aerosols KW - Atmospheric pollution KW - Nitrates KW - Organic aerosols in atmosphere KW - Sulfate aerosols KW - Pollutant deposition KW - winter KW - Numerical simulations KW - hydrogen peroxide KW - summer KW - Urban atmospheric pollution KW - Rural areas KW - Q2 09243:Structure, mechanics and thermodynamics KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20597921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology+and+Climatology&rft.atitle=Impact+of+an+Updated+Carbon+Bond+Mechanism+on+Predictions+from+the+CMAQ+Modeling+System%3A+Preliminary+Assessment&rft.au=Sarwar%2C+G%3BLuecken%2C+D%3BYarwood%2C+G%3BWhitten%2C+G+Z%3BCarter%2C+WPL&rft.aulast=Sarwar&rft.aufirst=G&rft.date=2008-01-01&rft.volume=47&rft.issue=1&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology+and+Climatology&rft.issn=15588424&rft_id=info:doi/10.1175%2F2007JAMC1393.1 L2 - http://ams.allenpress.com/perlserv/?request=get-abstract&doi=10.1175%2F2007JAMC1393.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Aerosols; Organic carbon; Climatology; Modelling; Ozone; Atmospheric pollution; Numerical simulations; Organic aerosols in atmosphere; Ozone concentration; Urban atmospheric pollution; Particulate matter in urban air; Air quality; Sulfate aerosols; Hydrogen; Rural areas; Sulfates; Nitrates; Formaldehyde; Pollutant deposition; Carbon; winter; hydrogen peroxide; summer; Urban areas DO - http://dx.doi.org/10.1175/2007JAMC1393.1 ER - TY - JOUR T1 - Preface: Marine and coastal applications in landscape ecology AN - 20580245; 8148194 AB - Landscape ecology traditionally has been limited to the study of terrestrial systems; however, the questions and methods defining the science are equally relevant for marine and coastal systems. The reciprocal relationship between spatial pattern and ecological processes and the overarching effect of scale on this relationship was being explored in some marine and coastal settings as the general discipline of landscape ecology was evolving throughout the latter two decades of the last century. As with all components of the biosphere, an understanding of these relationships is critical for successful management of marine and coastal systems. In these systems, widely dispersed field or ship-based observations and lack of broad scale data have historically precluded quantification of large-scale patterns and processes and hindered management efforts. However, relatively recent advances in geographic information systems, remote sensing and computer technologies have begun to address these issues and are now permitting assessments of pattern and process in oceans. The intent of this special issue is to highlight research that is adapting the tools of landscape ecology to answer ecological questions within marine and coastal systems, to address the unique challenges faced in these landscapes, and to stimulate an exchange of ideas and solutions to common problems. Inspiration for this special issue of Landscape Ecology began with a special session on 'Marine and Coastal Applications in Landscape Ecology' that was held at the 19th Annual Symposium of the United States Regional Association of the International Association for Landscape Ecology, March 31-April 2, 2004 in Las Vegas, Nevada. JF - Landscape Ecology AU - Hinchey, Elizabeth K AU - Nicholson, Matthew C AU - Zajac, Roman N AU - Irlandi, Elizabeth A AD - Purdue University, 77 West Jackson Blvd. (G-17J), Chicago, IL, 60604, USA, hinchey.elizabeth@epa.gov Y1 - 2008/01// PY - 2008 DA - January 2008 SP - 1 EP - 5 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 23 SN - 0921-2973, 0921-2973 KW - Ecology Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Oceanic Abstracts KW - Marine KW - Computers KW - Ecological distribution KW - Landscape KW - Remote sensing KW - Brackish KW - USA, Nevada, Las Vegas KW - USA, Nevada KW - Biosphere KW - Freshwater KW - Coastal zone management KW - Coastal zone KW - Interspecific relationships KW - Oceans KW - Geographic information systems KW - O 1070:Ecology/Community Studies KW - D 04040:Ecosystem and Ecology Studies KW - Q2 09124:Coastal zone management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20580245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Landscape+Ecology&rft.atitle=Preface%3A+Marine+and+coastal+applications+in+landscape+ecology&rft.au=Hinchey%2C+Elizabeth+K%3BNicholson%2C+Matthew+C%3BZajac%2C+Roman+N%3BIrlandi%2C+Elizabeth+A&rft.aulast=Hinchey&rft.aufirst=Elizabeth&rft.date=2008-01-01&rft.volume=23&rft.issue=&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Landscape+Ecology&rft.issn=09212973&rft_id=info:doi/10.1007%2Fs10980-007-9141-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-25 N1 - SubjectsTermNotLitGenreText - Coastal zone; Interspecific relationships; Ecological distribution; Remote sensing; Coastal zone management; Computers; Oceans; Landscape; Geographic information systems; Biosphere; USA, Nevada, Las Vegas; USA, Nevada; Freshwater; Brackish; Marine DO - http://dx.doi.org/10.1007/s10980-007-9141-3 ER - TY - JOUR T1 - Theoretical and Experimental Approaches to Address Possible Thresholds of Response in Carcinogenicity AN - 20453250; 9128575 AB - The determination and utilization of the actual low dose-response relationship for chemical carcinogens has long interested toxicologists, experimental pathologists, modelers and risk assessors. To date, no unequivocal examples of carcinogenic thresholds in humans are known. However, at least 5 examples of thresholds of preneoplastic foci or tumors have been observed in animals. The two largest dose-response studies utilized 20,880 mice (2-acetylaminofluorene) and 7,200 rainbow trout fry (aflatoxins). In both of these studies linear relationships were observed for DNA adducts and for liver tumors. A threshold relationship was observed for 2- acetylaminofluorene induced mouse urinary bladder cancer. Other comprehensive dose-response studies have examined the chemicals 2-amino-3,8- dimethylimidazo[4,5-f]-quinoxaline, 2-amino-1-methyl-6-phenolimidazo[4,5- b]pyridine and diethylnitrosamine. Taken collectively, the DNA adduct data for these 6 well studied chemicals are fairly linear. The foci and tumor data show either supralinear, linear or threshold curves, making it difficult to generalize. All the 6 studied chemicals cause multiple biological effects including genotoxicity, cytotoxicity and cell proliferation in complex dose and time dependent patterns that are not fully understood. We do know that there are multiple possible biological defenses (at least 7 pharmacokinetic and 7 pharmacodynamic) against the development of cancer. Currently, we have limited scientific and regulatory understanding of chemicals that act simultaneously or sequentially via both linear and nonlinear carcinogenic pathways (genotoxic and nongenotoxic). If an 100% experimental approach is used to elucidate the dose-response of chemicals of dual carcinogenic dose- response properties (linear and non linear), this would require studying 2 or more such chemicals in a large scale coordinated fashion employing at least 1,000 animals, 5 different treatment groups, 7 different study parameters and 8 different scientific disciplines. JF - Genes and Environment AU - Kitchin, Kirk T AD - Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 150 EP - 159 PB - The Japanese Environmental Mutagen Society VL - 30 IS - 4 SN - 1880-7046, 1880-7046 KW - Toxicology Abstracts; Genetics Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Sustainability Science Abstracts KW - cancer KW - threshold KW - dose-response KW - genotoxic KW - mutagenic KW - biological effects KW - tumors KW - Carcinogens KW - urinary bladder KW - Carcinogenicity KW - Dose-response effects KW - Pharmacodynamics KW - DNA adducts KW - Data processing KW - Urinary bladder KW - Genotoxicity KW - Aflatoxins KW - Diethylnitrosamine KW - Oncorhynchus mykiss KW - Mice KW - Tumors KW - Pharmacokinetics KW - Cancer KW - Cytotoxicity KW - DNA KW - Liver KW - Cell proliferation KW - X 24370:Natural Toxins KW - M3 1010:Issues in Sustainable Development KW - N 14820:DNA Metabolism & Structure KW - G 07730:Development & Cell Cycle UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20453250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Genes+and+Environment&rft.atitle=Theoretical+and+Experimental+Approaches+to+Address+Possible+Thresholds+of+Response+in+Carcinogenicity&rft.au=Kitchin%2C+Kirk+T&rft.aulast=Kitchin&rft.aufirst=Kirk&rft.date=2008-01-01&rft.volume=30&rft.issue=4&rft.spage=150&rft.isbn=&rft.btitle=&rft.title=Genes+and+Environment&rft.issn=18807046&rft_id=info:doi/10.3123%2Fjemsge.30.150 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-04-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - DNA adducts; Data processing; Urinary bladder; Genotoxicity; Aflatoxins; Diethylnitrosamine; Tumors; Carcinogens; Cancer; Pharmacokinetics; Cytotoxicity; Carcinogenicity; Dose-response effects; Liver; Cell proliferation; Pharmacodynamics; biological effects; Mice; tumors; urinary bladder; DNA; Oncorhynchus mykiss DO - http://dx.doi.org/10.3123/jemsge.30.150 ER - TY - JOUR T1 - The role of power generation technology in mitigating global climate change AN - 20400924; 9069865 AB - Anthropogenic emissions of greenhouse gases, especially carbon dioxide, CO sub(2) have led to increasing atmospheric concentrations which are mostly responsible for the roughly 0.8 degree C global warming the Earth has experienced since the Industrial Revolution. With industrial activity and population expected to increase throughout the rest of the century, large increases in greenhouse gas emissions are projected, with additional and potentially substantial subsequent global warming predicted. Using a powerful PC-based global climate model, global warming is projected for two business as usual cases, as well as simple yet instructive scenarios in which major programs are initiated to limit CO sub(2) emissions. This paper provides a brief overview of the forces driving CO sub(2) emissions, how different CO sub(2) emission trajectories could affect temperature this century, with a focus on power generation mitigation options, and research and development priorities. While much literature exists on various aspects of this subject, this paper aims to provide a succinct integration of our best knowledge of the projected warming the Earth is likely to experience in the decades ahead, the emission reductions that may be needed to constrain this warming to tolerable levels, and the technologies potentially available to help achieve these emission reductions. JF - Duke Environmental Law & Policy Forum AU - Princiotta, F AD - Air Pollution Prevention and Control Division, National Risk Management Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, USA PY - 2008 SP - 251 VL - 18 IS - 2 SN - 1064-3958, 1064-3958 KW - Sustainability Science Abstracts; Pollution Abstracts; Environment Abstracts KW - anthropogenic factors KW - Climatic changes KW - Temperature KW - Emission control KW - Greenhouse effect KW - environmental law KW - mitigation KW - Electric power generation KW - Emissions KW - Global warming KW - Industrial areas KW - Greenhouse gases KW - Carbon dioxide KW - Research programs KW - Technology KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20400924?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Duke+Environmental+Law+%26+Policy+Forum&rft.atitle=The+role+of+power+generation+technology+in+mitigating+global+climate+change&rft.au=Princiotta%2C+F&rft.aulast=Princiotta&rft.aufirst=F&rft.date=2008-01-01&rft.volume=18&rft.issue=2&rft.spage=251&rft.isbn=&rft.btitle=&rft.title=Duke+Environmental+Law+%26+Policy+Forum&rft.issn=10643958&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-03-01 N1 - Last updated - 2015-12-16 N1 - SubjectsTermNotLitGenreText - anthropogenic factors; Climatic changes; Temperature; Greenhouse effect; Emission control; environmental law; mitigation; Electric power generation; Emissions; Global warming; Industrial areas; Carbon dioxide; Greenhouse gases; Research programs; Technology ER - TY - JOUR T1 - A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards AN - 20345040; 9023293 AB - Background In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potential differences in the amplification performance of plasmid DNA compared to genomic DNA standards are often ignored in calibration calculations and in some cases impossible to characterize. A flexible statistical method that can account for uncertainty between plasmid and genomic DNA targets, replicate testing, and experiment-to-experiment variability is needed to estimate calibration curve parameters such as intercept and slope. Here we report the use of a Bayesian approach to generate calibration curves for the enumeration of target DNA from genomic DNA samples using absolute plasmid DNA standards. Results Instead of the two traditional methods (classical and inverse), a Monte Carlo Markov Chain (MCMC) estimation was used to generate single, master, and modified calibration curves. The mean and the percentiles of the posterior distribution were used as point and interval estimates of unknown parameters such as intercepts, slopes and DNA concentrations. The software WinBUGS was used to perform all simulations and to generate the posterior distributions of all the unknown parameters of interest. Conclusion The Bayesian approach defined in this study allowed for the estimation of DNA concentrations from environmental samples using absolute standard curves generated by real-time qPCR. The approach accounted for uncertainty from multiple sources such as experiment-to-experiment variation, variability between replicate measurements, as well as uncertainty introduced when employing calibration curves generated from absolute plasmid DNA standards. JF - BMC Bioinformatics AU - Sivaganesan, Mano AU - Seifring, Shawn AU - Varma, Manju AU - Haugland, Richard A AU - Shanks, Orin C AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, 26 West Martin Luther King Drive, Cincinnati, OH 45268, USA, sivaganesan.mano@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 120 PB - BioMed Central Ltd., Middlesex House VL - 9 KW - Genetics Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Biotechnology and Bioengineering Abstracts KW - Computer programs KW - software KW - Statistics KW - Bayesian analysis KW - Polymerase chain reaction KW - genomics KW - Bioinformatics KW - Plasmids KW - G 07880:Human Genetics KW - N 14810:Methods KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20345040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Bioinformatics&rft.atitle=A+Bayesian+method+for+calculating+real-time+quantitative+PCR+calibration+curves+using+absolute+plasmid+DNA+standards&rft.au=Sivaganesan%2C+Mano%3BSeifring%2C+Shawn%3BVarma%2C+Manju%3BHaugland%2C+Richard+A%3BShanks%2C+Orin+C&rft.aulast=Sivaganesan&rft.aufirst=Mano&rft.date=2008-01-01&rft.volume=9&rft.issue=&rft.spage=120&rft.isbn=&rft.btitle=&rft.title=BMC+Bioinformatics&rft.issn=1471-2105&rft_id=info:doi/10.1186%2F1471-2105-9-120 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-03-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Computer programs; software; Statistics; Bayesian analysis; Polymerase chain reaction; Bioinformatics; genomics; Plasmids DO - http://dx.doi.org/10.1186/1471-2105-9-120 ER - TY - JOUR T1 - An experimental study of fire and moisture stress on the survivorship of savanna eucalypt seedlings AN - 20282477; 8938963 AB - Eucalyptus melanophloia and E. populnea dominate large areas of savanna in eastern Australia. Under aboriginal management, fires probably occurred under a broad range of conditions, but under pastoral management, burning is avoided when soil moisture is low. This experiment subjected E. melanophloia and E. populnea seedlings to burning and moisture stress, to examine whether this change in burning regime could affect seedling survivorship. The findings suggest survivorship rates are 87-93% for unstressed seedlings with relatively large lignotubers (>12 mm super(2) plan area) and 56-66% for unstressed seedlings with small lignotubers. There was no substantial interactive effect between moisture stress and burning for E. melanophloia, but such an interaction was apparent for E. populnea, such that moisture stress multiplied the effect of burning. The timing of burning in relation to soil-moisture conditions may have an enduring effect on woodland structure where E. populnea is dominant. E. melanophloia seedlings are more resistant to burning, especially with moisture stress, and fire may not be limiting structural development in woodlands where this species dominates. However, a more detailed understanding of species demography is required, including the conditions required for germination, causes of seedling mortality and the time taken for seedlings to develop fire resistance in the field. JF - Australian Journal of Botany AU - Fensham, R J AU - Fairfax, R J AU - Buckley, Y M AD - Queensland Herbarium, Environmental Protection Agency, Mt Coot-tha Road, Toowong, Qld 4066, Australia, rod.fensham@epa.qld.gov.au Y1 - 2008 PY - 2008 DA - 2008 SP - 693 EP - 697 PB - CSIRO Publishing, PO Box 1139 150 Oxford Street Collingwood Vic. 3066 Australia, [mailto:publishing@csiro.au], [URL:http://www.publish.csiro.au/] VL - 56 IS - 8 SN - 0067-1924, 0067-1924 KW - Ecology Abstracts; Sustainability Science Abstracts KW - demography KW - Germination KW - Fires KW - Mortality KW - botany KW - Stress KW - Survival KW - burning KW - Eucalyptus KW - Savannahs KW - Australia KW - Seedlings KW - Burning KW - Soil moisture KW - germination KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20282477?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Australian+Journal+of+Botany&rft.atitle=An+experimental+study+of+fire+and+moisture+stress+on+the+survivorship+of+savanna+eucalypt+seedlings&rft.au=Fensham%2C+R+J%3BFairfax%2C+R+J%3BBuckley%2C+Y+M&rft.aulast=Fensham&rft.aufirst=R&rft.date=2008-01-01&rft.volume=56&rft.issue=8&rft.spage=693&rft.isbn=&rft.btitle=&rft.title=Australian+Journal+of+Botany&rft.issn=00671924&rft_id=info:doi/10.1071%2FBT08152 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Germination; Mortality; Savannahs; Fires; Survival; Stress; Seedlings; Burning; demography; botany; Soil moisture; burning; germination; Eucalyptus; Australia DO - http://dx.doi.org/10.1071/BT08152 ER - TY - JOUR T1 - A convective flow biofilter for the biofiltration of contaminants at sub-low concentrations AN - 20265822; 8903992 AB - Biofiltration of contaminants at concentrations below a certain level (sub-low concentrations) is not as effective as at higher concentrations, which leads to incomplete removal of the contaminants, because of diffusive mass transfer of the contaminants inside the biofilm and insufficient carbon and energy sources to sustain biomass growth and maintenance. To overcome the limitation of diffusion, this article proposes the concept of convective flow biofilm in which contaminated air flows through the porous biofilm and thus carries the carbon and energy sources to the biomass. The innovative concept of convective flow biofilm was implemented in a convective flow biofilter (CFB), which was built from activated carbon-coated ceramic monoliths by selectively blocking the channel openings. The CFB was tested for 11 weeks for the biofiltration of toluene at inlet concentrations below 100 ppmv. The CFB performed consistently better than the conventional diffusive flow biofilter (DFB), as indicated by the higher removal efficiencies and the higher CO2 productions. The CFB demonstrated up to 30 percent higher removal efficiency and an up to 100 percent higher elimination capacity than the DFB. JF - Remediation AU - Fang, Yuanxiang AU - Govind, Rakesh AD - National Risk Management Research Laboratory, U.S. Environmental Protection Agency Y1 - 2008 PY - 2008 DA - 2008 SP - 95 EP - 107 PB - John Wiley & Sons, 111 River Street Hoboken NJ 07030 USA, [mailto:custserv@wiley.com], [URL:http://www.wiley.com/] VL - 18 IS - 1 SN - 1051-5658, 1051-5658 KW - Pollution Abstracts KW - Bioremediation KW - Toluene KW - Biomass KW - Energy sources KW - Maintenance KW - Ceramics KW - Channels KW - Biofiltration KW - air flow KW - Diffusion KW - Biofilms KW - Contaminants KW - Carbon dioxide KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20265822?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Remediation&rft.atitle=A+convective+flow+biofilter+for+the+biofiltration+of+contaminants+at+sub-low+concentrations&rft.au=Fang%2C+Yuanxiang%3BGovind%2C+Rakesh&rft.aulast=Fang&rft.aufirst=Yuanxiang&rft.date=2008-01-01&rft.volume=18&rft.issue=1&rft.spage=95&rft.isbn=&rft.btitle=&rft.title=Remediation&rft.issn=10515658&rft_id=info:doi/10.1002%2Frem.20154 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Bioremediation; Toluene; Biomass; Energy sources; Maintenance; Biofiltration; Channels; Ceramics; air flow; Diffusion; Biofilms; Carbon dioxide; Contaminants DO - http://dx.doi.org/10.1002/rem.20154 ER - TY - JOUR T1 - Treatment technologies for mercury in soil, waste, and water AN - 20265795; 8903987 AB - Mercury occurs naturally in the environment and can be found in elemental (metallic), inorganic, and organic forms. Modern uses for mercury include chemical manufacturing, thermometers, and lighting (mercury vapor and fluorescent lamps). The chemical and allied products industry group is responsible for the largest quantity of mercury used in the United States. Mercury, particularly the organic methylmercury form, is a potent neurotoxin capable of impairing neurological development in fetuses and young children and of damaging the central nervous system of adults. Mercury regulations span multiple federal and state environmental statutes, as well as multiple agency jurisdictions. In August 2007, the U.S. Environmental Protection Agency's (US EPA's) Office of Superfund Remediation and Technology Innovation (OSRTI) published a report titled Treatment Technologies for Mercury in Soil, Waste, and Water. The report identifies eight treatment technologies and 57 projects, 50 of which provide performance data. This information can help managers at sites with mercury-contaminated media and generators of mercury-contaminated waste and wastewater to identify proven and effective mercury treatment technologies; screen technologies based on application-specific goals, characteristics, and costs; and apply experiences from sites with similar treatment challenges. This article provides a synopsis of the US EPA report, which is available at http://clu-in.org/542R07003. JF - Remediation AU - Otto, Martha AU - Bajpai, Sankalpa AD - Office of Solid Waste and Emergency Response, US EPA Y1 - 2008 PY - 2008 DA - 2008 SP - 21 EP - 28 PB - John Wiley & Sons, 111 River Street Hoboken NJ 07030 USA, [mailto:custserv@wiley.com], [URL:http://www.wiley.com/] VL - 18 IS - 1 SN - 1051-5658, 1051-5658 KW - Water Resources Abstracts; Pollution Abstracts KW - Central nervous system KW - Bioremediation KW - Jurisdiction KW - Lighting KW - jurisdiction KW - Wastewater treatment KW - Soil KW - Vapors KW - Thermometers KW - Regulations KW - Methylmercury KW - Superfund KW - Wastes KW - Environmental Protection KW - Toxicity KW - Children KW - Fetuses KW - EPA KW - USA KW - Water Pollution Effects KW - Remediation KW - Mercury KW - innovations KW - Neurotoxins KW - Technology KW - P 3000:SEWAGE & WASTEWATER TREATMENT KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20265795?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Remediation&rft.atitle=Treatment+technologies+for+mercury+in+soil%2C+waste%2C+and+water&rft.au=Otto%2C+Martha%3BBajpai%2C+Sankalpa&rft.aulast=Otto&rft.aufirst=Martha&rft.date=2008-01-01&rft.volume=18&rft.issue=1&rft.spage=21&rft.isbn=&rft.btitle=&rft.title=Remediation&rft.issn=10515658&rft_id=info:doi/10.1002%2Frem.20150 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-02-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Central nervous system; Methylmercury; Bioremediation; Superfund; Lighting; jurisdiction; Children; Wastewater treatment; Fetuses; Soil; EPA; Vapors; Mercury; innovations; Neurotoxins; Technology; Water Pollution Effects; Jurisdiction; Thermometers; Remediation; Wastes; Environmental Protection; Regulations; Toxicity; USA DO - http://dx.doi.org/10.1002/rem.20150 ER - TY - JOUR T1 - Integrated Disinfection By-Products Research: Assessing Reproductive and Developmental Risks Posed by Complex Disinfection By-Product Mixtures AN - 20253946; 8537161 AB - This article presents a toxicologically-based risk assessment strategy for identifying the individual components or fractions of a complex mixture that are associated with its toxicity. The strategy relies on conventional component-based mixtures risk approaches such as dose addition, response addition, and analyses of interactions. Developmental toxicity data from two drinking-water concentrates containing disinfection by-products (DBP) mixtures were used to illustrate the strategy. The results of this study showed that future studies of DBP concentrates using the Chernoff-Kavlock bioassay need to consider evaluating DBP that are concentrated more than 130-fold and using a rat strain that is more sensitive to chemically-induced pregnancy loss than Sprague-Dawley rats. The results support the planned experimental design of a multigeneration reproductive and developmental study of DBP concentrates. Finally, this article discusses the need for a systematic evaluation of DBP concentrates obtained from multiple source waters and treatment types. The development of such a database could be useful in evaluating whether a specific DBP concentrate is sufficiently similar to tested combinations of source waters and treatment alternatives so that health risks for the former may be estimated using data on the latter. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Rice, G AU - Teuschler, L K AU - Speth, T F AU - Richardson, S D AU - Miltner, R J AU - Schenck, K M AU - Gennings, C AU - Hunter, ES III AU - Narotsky, M G AU - Simmons, JE AD - U.S. Environmental Protection Agency, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA, rice.glenn@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1222 EP - 1234 VL - 71 IS - 17-18 SN - 1528-7394, 1528-7394 KW - Water Resources Abstracts; Environment Abstracts; Toxicology Abstracts; Risk Abstracts; Pollution Abstracts KW - Risk assessment KW - Disinfection KW - Abortion KW - Byproducts KW - Evaluation KW - Rats KW - Drinking Water KW - Public Health KW - Water treatment KW - Data processing KW - Toxicity KW - Pregnancy KW - Risk KW - Databases KW - Bioassays KW - Water Pollution Effects KW - Experimental Design KW - disinfection KW - Drinking water KW - X 24340:Cosmetics, Toiletries & Household Products KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - R2 23060:Medical and environmental health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20253946?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Integrated+Disinfection+By-Products+Research%3A+Assessing+Reproductive+and+Developmental+Risks+Posed+by+Complex+Disinfection+By-Product+Mixtures&rft.au=Rice%2C+G%3BTeuschler%2C+L+K%3BSpeth%2C+T+F%3BRichardson%2C+S+D%3BMiltner%2C+R+J%3BSchenck%2C+K+M%3BGennings%2C+C%3BHunter%2C+ES+III%3BNarotsky%2C+M+G%3BSimmons%2C+JE&rft.aulast=Rice&rft.aufirst=G&rft.date=2008-01-01&rft.volume=71&rft.issue=17-18&rft.spage=1222&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802182649 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Databases; Disinfection; Data processing; Abortion; Toxicity; Rats; Bioassays; Water treatment; Byproducts; disinfection; Drinking water; Pregnancy; Evaluation; Risk; Public Health; Drinking Water; Water Pollution Effects; Experimental Design DO - http://dx.doi.org/10.1080/15287390802182649 ER - TY - JOUR T1 - Integrated Disinfection By-Products Mixtures Research: Concentration by Reverse Osmosis Membrane Techniques of Disinfection By-Products from Water Disinfected by Chlorination and Ozonation/Postchlorination AN - 20252304; 8537156 AB - To conduct the health-effect studies described in subsequent articles in this series, concentrated aqueous mixtures of disinfection by-products were required for the two water treatment trains described in the preceding article (Miltner et al., 2008). To accomplish this, the finished drinking waters from each treatment train were sent through cation-exchange resin columns to remove hardness and free chlorine. Reverse osmosis membranes were then used to concentrate approximately 2400 L of each finished water down to approximately 18 L. The resulting volumetric concentration factors for the chlorinated and ozonated/postchlorinated waters were 136- and 124-fold, respectively. The concentrates were spiked with select disinfection by-products (DBPs) that were lost during the concentration effort The results, along with the rationale for choosing the method of concentration, are presented. After reintroduction of a select list of lost DBPs, the concentration methodology used herein was able to produce concentrates that retained large percentages of the DBPs that were in the initial finished drinking waters. Further, the distributions of the DBPs in the concentrates matched those found in the finished drinking waters. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Speth, T F AU - Miltner, R J AU - Richardson, S D AU - Simmons, JE AD - U.S. Environmental Protection Agency, National Risk Management Research Laboratory, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA, Speth.Thomas@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1149 EP - 1164 VL - 71 IS - 17-18 SN - 1528-7394, 1528-7394 KW - Health & Safety Science Abstracts; Pollution Abstracts; Water Resources Abstracts; Environment Abstracts; Toxicology Abstracts KW - Disinfection KW - Reverse osmosis KW - Byproducts KW - Chlorine KW - Drinking Water KW - Water treatment KW - Water Treatment KW - Ozonation KW - Reintroduction KW - Resins KW - Membranes KW - Hardness KW - Reverse Osmosis KW - disinfection KW - Chlorination KW - Drinking water KW - reintroduction KW - H 3000:Environment and Ecology KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - X 24360:Metals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20252304?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Integrated+Disinfection+By-Products+Mixtures+Research%3A+Concentration+by+Reverse+Osmosis+Membrane+Techniques+of+Disinfection+By-Products+from+Water+Disinfected+by+Chlorination+and+Ozonation%2FPostchlorination&rft.au=Speth%2C+T+F%3BMiltner%2C+R+J%3BRichardson%2C+S+D%3BSimmons%2C+JE&rft.aulast=Speth&rft.aufirst=T&rft.date=2008-01-01&rft.volume=71&rft.issue=17-18&rft.spage=1149&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802182219 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Reintroduction; Disinfection; Resins; Reverse osmosis; Water treatment; Chlorine; Chlorination; Drinking water; Ozonation; Membranes; disinfection; Byproducts; reintroduction; Drinking Water; Water Treatment; Hardness; Reverse Osmosis DO - http://dx.doi.org/10.1080/15287390802182219 ER - TY - JOUR T1 - U.S.--Canada Cooperation: The U.S.--Canada Air Quality Agreement AN - 20251388; 8355015 AB - The impetus for the Canada--U.S. Air Quality Agreement was transboundary acid rain in eastern North America. This problem drove the parties to develop a bilateral agreement that not only addressed this issue, but also set up a broad and flexible framework to address other air quality problems. In 2000, the Ozone Annex to reduce smog and its precursor pollutants was negotiated. A transboundary particulate matter (PM) science assessment in 2004 led to the commencement of negotiation of a PM annex in late 2007. Over the course of 15 yr, Canada and the United States also developed innovative cooperative arrangements. Two transboundary airshed dialogues became important sources of practical on-the-ground cooperation in the Georgia Basin-Puget Sound and the Great Lakes Basin. In addition to providing the basis for ongoing international dialogue, these transboundary airshed projects resulted in changes to administrative practices as the parties exchange information and learn from each other in ways that benefit the airshed community. The nature of the Air Quality Agreement also enabled both Canada and the United States to address concerns each has had about specific pollutant sources and to address them in ways that avoided confrontation and resulted in air quality improvements for people living in the airsheds. Case studies of three of the "informal consultations" that have occurred under the agreement are described: where discussions occurred around a power plant in Michigan, a power plant in Saskatchewan, and a steel mill in Ontario. More than an agreement, this relationship has built a capacity to deal with common problems. Fostering such a relationship with its implicit transfer of knowledge and experience has opened doors for discussions on a new Clean Air framework in Canada and joint analyses of cross-border sulfur dioxide (SO sub(2)) and nitrogen oxides (NO sub(X)) emissions caps and trading. US experience with cap and trading is highlighted for background and context. The flexibility inherent in the agreement provides a platform for future air quality issues and continued communication without borders. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - McLean, B AU - Barton, J AD - Office of Atmospheric Programs, US Environmental Protection Agency, 1200 Pennsylvania Avenue, 6204J, Washington, DC 20460, USA, mclean.brian@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 564 EP - 569 VL - 71 IS - 9-10 SN - 1528-7394, 1528-7394 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts; Environment Abstracts; Toxicology Abstracts KW - Sulfur in atmosphere KW - Cooperation KW - Particulate matter KW - Communication KW - Basins KW - Air quality KW - Particulates KW - Ozone in troposphere KW - Sulfur dioxide KW - North America, Great Lakes Basin KW - Pollutants KW - lake basins KW - Trans-boundary pollution KW - Sound KW - Power plants KW - oxides KW - Smog KW - Steel KW - cooperatives KW - Ozone KW - Atmospheric pollution KW - Acid rain KW - Canada, Saskatchewan KW - USA, Georgia KW - Nitrogen oxides KW - Metal industry KW - case studies KW - Air pollution KW - Communications KW - Acid precipitation KW - Nitrogen KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - X 24490:Other KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20251388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=U.S.--Canada+Cooperation%3A+The+U.S.--Canada+Air+Quality+Agreement&rft.au=McLean%2C+B%3BBarton%2C+J&rft.aulast=McLean&rft.aufirst=B&rft.date=2008-01-01&rft.volume=71&rft.issue=9-10&rft.spage=564&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390801997567 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Acid rain; Cooperation; Particulate matter; Communication; Basins; Sulfur dioxide; Pollutants; Power plants; Sound; oxides; Steel; Smog; Nitrogen; Ozone; Ozone in troposphere; Atmospheric pollution; Acid precipitation; Sulfur in atmosphere; Air quality; Particulates; Metal industry; Nitrogen oxides; Air pollution; case studies; Communications; Trans-boundary pollution; lake basins; cooperatives; North America, Great Lakes Basin; Canada, Saskatchewan; USA, Georgia DO - http://dx.doi.org/10.1080/15287390801997567 ER - TY - JOUR T1 - Catch me if you can - the misapplication of the federal statute of limitations to Clean Air Act PSD permit program violations AN - 20237819; 8491959 AB - One of the most important goals of the federal Clean Air Act (CAA) is the maintenance of minimum air quality standards throughout the nation. The air quality standards are known as the National Ambient Air Quality Standards (NAAQS) and cover criteria pollutants, such as nitrogen oxides, sulfur dioxides, and ozone. The Prevention of Significant Deterioration (PSD) permit program, first enacted by Congress in 1977, is one of the United States government's key tools for maintaining minimum air quality in areas already meeting the NAAQS. The PSD program requires that all new or modified major stationary sources obtain a preconstruction permit and apply stringent emissions controls meeting best available control technology (BACT). Sources that construct or modify major stationary sources without complying with the PSD requirements are subject to enforcement by citizens and the United States Environmental Protection Agency (EPA), the federal regulatory body charged with implementing the PSD program. Defendants of PSD lawsuits increasingly raise as a defense to penalties the application of the five year federal statute of limitations. Since the CAA does not contain an explicit statute of limitations provision, courts generally apply the federal statute of limitations to PSD penalty claims. Defendants seeking dismissal of those claims generally argue that PSD violations are one-time events occurring at the time of construction of new or modified sources. Under this theory, penalties will be barred if the court finds that the unpermitted construction occurred more than five years prior to the Sling of the complaint. On the other hand, citizens and the government, seeking to properly punish wrongdoers and deter future PSD violations, argue that the requirement to have a PSD permit and apply BACT for a new or modified source continues until a source meets those requirements. Under this continuing violation theory, a plaintiff can seek penalties for the five years prior to the filing of the complaint even if the violation first accrued more than five years prior to the commencement of the lawsuit. In recent years, numerous courts ruling on the issue have been sharply divided as to whether PSD violations are one-time events or ongoing violations for statute of limitations purposes. Indeed, the only two circuit courts to rule directly on the issue, the Sixth and Eleventh Circuits, are also divided on the issue. In these two circuit court cases, the same plaintiffs, the National Parks Conservation Ass'n and Sierra Club, sued the Tennessee Valley Authority (TVA) claiming PSD violations at different TVA power plants. This Article examines these numerous court cases, describes the history and nuances of the PSD program, and ultimately takes the position that those courts finding that PSD violations are continuing in nature are correct based upon the broad remedial goals and statutory language of the CAA, the legislative history of the PSD program, EPA's interpretation of the PSD program, and other considerations. JF - Environmental Law (Portland) AU - Lieben, I AD - United States Environmental Protection Agency in San Francisco, California, USA Y1 - 2008 PY - 2008 DA - 2008 SP - 667 EP - 710 VL - 38 IS - 3 SN - 0046-2276, 0046-2276 KW - Pollution Abstracts; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts; Environment Abstracts KW - Historical account KW - courts KW - Sulfur in atmosphere KW - Air quality KW - Clean Air Act KW - Ozone in troposphere KW - Stationary sources KW - prevention KW - Power plants KW - Congresses KW - Atmospheric pollution KW - valleys KW - Congress KW - Emission control KW - Nitrogen oxides KW - Maintenance KW - Environmental protection KW - Air quality standards KW - USA, Tennessee KW - EPA KW - USA KW - Conservation KW - Litigation KW - Legislation KW - Technology KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20237819?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Law+%28Portland%29&rft.atitle=Catch+me+if+you+can+-+the+misapplication+of+the+federal+statute+of+limitations+to+Clean+Air+Act+PSD+permit+program+violations&rft.au=Lieben%2C+I&rft.aulast=Lieben&rft.aufirst=I&rft.date=2008-01-01&rft.volume=38&rft.issue=3&rft.spage=667&rft.isbn=&rft.btitle=&rft.title=Environmental+Law+%28Portland%29&rft.issn=00462276&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Clean Air Act; Air quality standards; Ozone in troposphere; Congresses; Atmospheric pollution; Sulfur in atmosphere; Conservation; Air quality; Environmental protection; Historical account; valleys; Congress; courts; Emission control; Nitrogen oxides; Maintenance; EPA; Stationary sources; Power plants; prevention; Litigation; Legislation; Technology; USA, Tennessee; USA ER - TY - JOUR T1 - Percutaneous Absorption of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) from Soil AN - 20233910; 8840881 AB - Eight dermal absorption experiments (two in vivo six in vitro) and one intravenous experiment were conducted using 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) either neat (high dose at similar to 250 mu g/cm super(2) and low dose at 10 ng/cm super(2)) or sorted on a low organic soil (LOS) or high organic soil (HOS) at 1 ppm (10 ng TCDD/10 mg soil/cm super(2)). After 96 h the percent of applied dose absorbed (PADA) for the neat low dose was 78% in vivo (rat) and 76% in vitro (rat). PADA for the equivalent TCDD dose sorbed on LOS were 16.3% (rat in vivo), 7.7% (rat in vitro) and 2.4% (human in vitro). The PADA for TCDD sorbed on HOS (1 ppm) was 1.0% (rat in vitro). Generally, rat skin was observed to be three to four times more permeable to TCDD than human skin. At steady state, the dermal flux of TCDD in neat form, sorbed on LOS at 1 ppm, and sorbed on HOS at 1 ppm (all in vitro, rat) was 120,0.007, and 0.0007 ng/cm super(2)/h, respectively (ratio = 1.7 x 10 super(5):10:1). Making adjustments to account for differences between in vitro and in vivo results and adjusting for application to monolayer loads, the 24-h TCDD absorption for human skin is estimated as 1.9% from LOS (1 ppm) and 0.24% from HOS (1 ppm). JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Roy, T A AU - Hammerstrom, K AU - Schaum, J AD - U.S. EPA, National Center for Environmental Assessment, Washington, DC, USA, schaum.john@epamail.epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1509 EP - 1515 VL - 71 IS - 23-24 SN - 1528-7394, 1528-7394 KW - Toxicology Abstracts; Environment Abstracts KW - Soil KW - Intravenous administration KW - Skin KW - organic soils KW - Absorption KW - TCDD KW - Soils (organic) KW - X 24350:Industrial Chemicals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20233910?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Percutaneous+Absorption+of+2%2C3%2C7%2C8-Tetrachlorodibenzo-p-dioxin+%28TCDD%29+from+Soil&rft.au=Roy%2C+T+A%3BHammerstrom%2C+K%3BSchaum%2C+J&rft.aulast=Roy&rft.aufirst=T&rft.date=2008-01-01&rft.volume=71&rft.issue=23-24&rft.spage=1509&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802349875 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Soil; Intravenous administration; Skin; TCDD; Soils (organic); organic soils; Absorption DO - http://dx.doi.org/10.1080/15287390802349875 ER - TY - JOUR T1 - Integrated Disinfection By-Products Research: Salmonella Mutagenicity of Water Concentrates Disinfected by Chlorination and Ozonation/Postchlorination AN - 20232418; 8537158 AB - Although chemical disinfection of drinking water is a highly protective public health practice, the disinfection process is known to produce toxic contaminants. Epidemiological studies associate chlorinated drinking water with quantitatively increased risks of rectal, kidney, and bladder cancer. One study found a significant exposure-response association between water mutagenicity and relative risk for bladder and kidney cancer. A number of studies found that several types of disinfection processes increase the level of mutagens detected by the Salmonella assay. As part of a comprehensive study to examine chlorinated and ozonated/postchlorinated drinking water for toxicological contaminants, the Salmonella mutagenicity assay was used to screen both volatile and nonvolatile organic components. The assay also compared the use of reverse osmosis and XAD resin procedures for concentrating the nonvolatile components. Companion papers provide the results from other toxicological assays and chemical analysis of the drinking water samples. The volatile components of the ozonated/postchlorinated and chlorinated water samples and a trihalomethane mixture were mutagenic to a Salmonella tester strain transfected with a rat theta-class glutathione S-transferase and predominantly nonmutagenic in the control strain. In this study, the nonvolatile XAD concentrate of the untreated water possessed a low level of mutagenic activity. However, compared to the levels of mutagenicity in the finished water XAD concentrates, the contribution from the settled source water was minimal. The mutagenicity seen in the reverse osmosis concentrates was < 50% of that seen in the XAD concentrates. Overall, mutagenic responses were similar to those observed in other North American studies and provide evidence that the pilot plant produced disinfection by-products similar to that seen in other studies. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Claxton, L D AU - Pegram, R AU - Schenck, K M AU - Simmons, JE AU - Warren, SH AD - Mail Drop B143-08, Environmental Carcinogenesis Division, U.S. EPA, Research, Triangle Park, NC 27709, USA, claxton.larry@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1187 EP - 1194 VL - 71 IS - 17-18 SN - 1528-7394, 1528-7394 KW - Microbiology Abstracts B: Bacteriology; Water Resources Abstracts; Environment Abstracts; Toxicology Abstracts KW - Risk assessment KW - Disinfection KW - Mutagens KW - Rectum KW - Reverse osmosis KW - Byproducts KW - Glutathione transferase KW - Strain KW - Public health KW - Drinking Water KW - Dose-response effects KW - Assay KW - Ozonation KW - North America KW - Mutagenicity KW - Resins KW - Kidneys KW - Reverse Osmosis KW - Cancer KW - Risk KW - Volatiles KW - Trihalomethanes KW - disinfection KW - Kidney KW - Chlorination KW - Contaminants KW - Drinking water KW - Salmonella KW - X 24340:Cosmetics, Toiletries & Household Products KW - SW 3060:Water treatment and distribution KW - J 02400:Human Diseases KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20232418?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Integrated+Disinfection+By-Products+Research%3A+Salmonella+Mutagenicity+of+Water+Concentrates+Disinfected+by+Chlorination+and+Ozonation%2FPostchlorination&rft.au=Claxton%2C+L+D%3BPegram%2C+R%3BSchenck%2C+K+M%3BSimmons%2C+JE%3BWarren%2C+SH&rft.aulast=Claxton&rft.aufirst=L&rft.date=2008-01-01&rft.volume=71&rft.issue=17-18&rft.spage=1187&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802182508 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Mutagens; Disinfection; Resins; Mutagenicity; Reverse osmosis; Rectum; Glutathione transferase; Cancer; Public health; Volatiles; Trihalomethanes; Dose-response effects; Chlorination; Drinking water; Contaminants; Ozonation; Byproducts; disinfection; Kidney; Risk; Drinking Water; Assay; Kidneys; Reverse Osmosis; Strain; Salmonella; North America DO - http://dx.doi.org/10.1080/15287390802182508 ER - TY - JOUR T1 - Integrated Disinfection By-Products Mixtures Research: Assessment of Developmental Toxicity in Sprague-Dawley Rats Exposed to Concentrates of Water Disinfected by Chlorination and Ozonation/Postchlorination AN - 20231250; 8537160 AB - Epidemiological and animal toxicity studies have raised concerns regarding possible adverse health effects of disinfection by-products (DBPs) found in drinking water. The classes and concentrations of DBPs are influenced by the choice of disinfection process (e.g., chlorination, ozonation) as well as source water characteristics (e.g., pH, total organic carbon, bromide content). Disinfected waters were found to contain more than 500 compounds, many of which remain unidentified. Therefore, a "whole-mixture" approach was used to evaluate the toxic potential of alternative disinfection scenarios. An in vivo developmental toxicity screen was used to evaluate the adverse developmental effects of the complex mixtures produced by two different disinfection processes. Water was obtained from East Fork Lake, Ohio; spiked with iodide and bromide; and disinfected either by chlorination or by ozonation/postchlorination, producing finished drinking water suitable for human consumption. These waters were concentrated approximately 130-fold by reverse osmosis membrane techniques. To the extent possible, volatile DBPs lost in the concentration process were spiked back into the concentrates. These concentrates were then provided as drinking water to Sprague-Dawley rats on gestation days 6-16; controls received boiled, distilled, deionized water. The dams (19-20 per group) were allowed to deliver and their litters were examined on postnatal days (PD) 1 and 6. All dams delivered normally, with parturition occurring significantly earlier in the ozonation/postchlorination group. However, no effects on prenatal survival, postnatal survival, or pup weight were evident. Skeletal examination of the PD-6 pups also revealed no treatment effects. Thus, 6130-fold higher concentrates of both ozonated/postchlorinated and chlorinated water appeared to exert no adverse developmental effects in this study. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Narotsky, M G AU - Best, D S AU - Rogers, E H AU - McDonald, A AU - Sey, Y M AU - Simmons, JE AD - NHEERL (MD-67), U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA, narotsky.michael@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1216 EP - 1221 VL - 71 IS - 17-18 SN - 1528-7394, 1528-7394 KW - Environment Abstracts; Toxicology Abstracts KW - Disinfection KW - Reverse osmosis KW - Byproducts KW - Parturition KW - Survival KW - bromides KW - Lakes KW - Water treatment KW - Dams KW - total organic carbon KW - Gestation KW - pH effects KW - Ozonation KW - Litter KW - Toxicity KW - USA, Colorado, Fork L. KW - Volatiles KW - disinfection KW - Chlorination KW - USA, Ohio KW - survival KW - Drinking water KW - X 24320:Food Additives & Contaminants KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20231250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Integrated+Disinfection+By-Products+Mixtures+Research%3A+Assessment+of+Developmental+Toxicity+in+Sprague-Dawley+Rats+Exposed+to+Concentrates+of+Water+Disinfected+by+Chlorination+and+Ozonation%2FPostchlorination&rft.au=Narotsky%2C+M+G%3BBest%2C+D+S%3BRogers%2C+E+H%3BMcDonald%2C+A%3BSey%2C+Y+M%3BSimmons%2C+JE&rft.aulast=Narotsky&rft.aufirst=M&rft.date=2008-01-01&rft.volume=71&rft.issue=17-18&rft.spage=1216&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802182623 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Disinfection; Litter; Reverse osmosis; Parturition; Survival; Toxicity; bromides; Lakes; Volatiles; total organic carbon; Gestation; Chlorination; Drinking water; pH effects; Ozonation; Water treatment; Dams; Byproducts; disinfection; survival; USA, Ohio; USA, Colorado, Fork L. DO - http://dx.doi.org/10.1080/15287390802182623 ER - TY - JOUR T1 - Integrated Disinfection By-Products Mixtures Research: Comprehensive Characterization of Water Concentrates Prepared from Chlorinated and Ozonated/Postchlorinated Drinking Water AN - 20231237; 8537157 AB - This article describes the disinfection by-product (DBP) characterization portion of a series of experiments designed for comprehensive chemical and toxicological evaluation of two drinking-water concentrates containing highly complex mixtures of DBPs. This project, called the Four Lab Study, involved the participation of scientists from four laboratories and centers of the U.S. Environmental Protection Agency (EPA) Office of Research and Development, along with collaborators from the water industry and academia, and addressed toxicologjc effects of complex DBP mixtures, with an emphasis on reproductive and developmental effects that are associated with DBP exposures in epidemiologic studies. Complex mixtures of DBPs from two different disinfection schemes (chlorination and ozonation/postchlorination) were concentrated successfully, while maintaining a water matrix suitable for animal studies. An array of chlorinated/brominated/iodinated DBPs was created. The DBPs were relatively stable over the course of the animal experiments, and a significant portion of the halogenated DBPs formed in the drinking water was accounted for through a comprehensive qualitative and quantitative identification approach. DBPs quantified included priority DBPs that are not regulated but have been predicted to produce adverse health effects, as well as those currently regulated in the United States and those targeted during implementation of the Information Collection Rule. New by-products were also reported for the first time. These included previously undetected and unreported bromo- and chloroacids, iodinated compounds, bromo- and iodophenols, and bromoalkyltins. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Richardson, S D AU - Thruston, AD Jr AU - Krasner, S W AU - Weinberg, H S AU - Miltner, R J AU - Schenck, K M AU - Narotsky, M G AU - McKague, AB AU - Simmons, JE AD - U.S. EPA, National Exposure Research Laboratory, 960 College Station Rd., Athens, GA 30605, USA, richardson.susan@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1165 EP - 1186 VL - 71 IS - 17-18 SN - 1528-7394, 1528-7394 KW - Health & Safety Science Abstracts; Pollution Abstracts; Water Resources Abstracts; Environment Abstracts; Toxicology Abstracts KW - Disinfection KW - Laboratories KW - Byproducts KW - Environmental Protection KW - Evaluation KW - EPA KW - USA KW - Drinking Water KW - Water treatment KW - disinfection KW - Priorities KW - Chlorination KW - Drinking water KW - Research programs KW - Ozonation KW - H 3000:Environment and Ecology KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - X 24320:Food Additives & Contaminants KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20231237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Integrated+Disinfection+By-Products+Mixtures+Research%3A+Comprehensive+Characterization+of+Water+Concentrates+Prepared+from+Chlorinated+and+Ozonated%2FPostchlorinated+Drinking+Water&rft.au=Richardson%2C+S+D%3BThruston%2C+AD+Jr%3BKrasner%2C+S+W%3BWeinberg%2C+H+S%3BMiltner%2C+R+J%3BSchenck%2C+K+M%3BNarotsky%2C+M+G%3BMcKague%2C+AB%3BSimmons%2C+JE&rft.aulast=Richardson&rft.aufirst=S&rft.date=2008-01-01&rft.volume=71&rft.issue=17-18&rft.spage=1165&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390802182417 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Disinfection; Chlorination; Drinking water; Ozonation; EPA; Water treatment; Byproducts; disinfection; Research programs; Evaluation; Drinking Water; Laboratories; Priorities; Environmental Protection; USA DO - http://dx.doi.org/10.1080/15287390802182417 ER - TY - JOUR T1 - Speciation and Atmospheric Abundance of Organic Compounds in PM2.5 from the New York City Area. I. Sampling Network, Sampler Evaluation, Molecular Level Blank Evaluation AN - 20046116; 8589984 AB - This study demonstrates an approach for evaluating a molecular level sampling and analysis protocol for organic marker compounds at the high picogram m-3 (ppt) to low nanogram m-3 (ppb) mass concentrations in urban and background receptor sites. The Speciation of Organics for Apportionment of PM2.5 in the New York City Area (SOAP) project was conducted from May 2002 to May 2003 at four sites in New York City, New Jersey, and Connecticut. Its chief objectives were to expand the chemical characterization of organic compounds and to estimate the source contributions of carbonaceous fine particles at urban and background monitoring sites. Two major challenges were faced in order to successfully implement the SOAP sampling network. First, collection of adequate fine PM mass was necessary for successful quantitation of organic marker compounds. Second, sufficiently low blank levels were required for each marker compound for accurate identification and quantitation needed for source-receptor modeling. Initial field tests of representative samplers designed for sampling PM chemical species indicated insufficient sample mass collection, unless analytical sensitivity for organic markers could be greatly improved. Adequate PM mass was collected using a Tisch TE-1202 sampler that operated at a much higher flow rate (113 lpm). Preliminary field tests also revealed unacceptably high travel blank levels for n-alkanes and carboxylic acids. The mass of organic marker compounds observed on travel blank filters was reduced significantly by shipping filters in sealed filter holders. Further evaluation of the Tisch TE-1202 sampler also demonstrated the sampler was free of organic components and impactor grease upstream of the filter. These features also reduced the contribution of carbonaceous species to system blanks and therefore, to the total mass collected. As a result, blank levels for hopanes, PAHs, and dicarboxylic acids were below limits of detection (LOD), and n-alkanes (C25 to C32), n-alkanoic acids (C12, C14, C16, and C18), and phthalic acid exhibited acceptable low levels in all SOAP blanks ranging from 1 to 10 times the limit of detection for each compound class. Overall, adequate sample mass and sufficiently low blank levels were achieved successfully with the SOAP fine particle collection protocol. JF - Aerosol Science & Technology AU - McDow, Stephen R AU - Mazurek, Monica A AU - Li, Min AU - Alter, Lee AU - Graham, John AU - Felton, H Dirk AU - McKenna, Thomas AU - Pietarinen, Charles AU - Leston, Alan AU - Bailey, Steve AU - Argao, Sania W Tong AD - Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, U.S. EPA, Research Triangle Park, North Carolina, USA Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 50 EP - 63 PB - Taylor & Francis, 325 Chestnut Street Suite 800 Philadelphia PA 19106 USA, [URL:http://www.taylorandfrancis.com/] VL - 42 IS - 1 SN - 0278-6826, 0278-6826 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Travel KW - USA, New Jersey KW - USA, Connecticut KW - Particulate matter in urban air KW - Particulates KW - Flow rates KW - upstream KW - USA, New York, New York City KW - Chemical speciation KW - Urban areas KW - Particle size KW - Sensitivity KW - Aerosols KW - Atmospheric pollution KW - Organic compounds in atmosphere KW - Filters KW - Carboxylic acids KW - Urban atmospheric pollution KW - abundance KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20046116?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerosol+Science+%26+Technology&rft.atitle=Speciation+and+Atmospheric+Abundance+of+Organic+Compounds+in+PM2.5+from+the+New+York+City+Area.+I.+Sampling+Network%2C+Sampler+Evaluation%2C+Molecular+Level+Blank+Evaluation&rft.au=McDow%2C+Stephen+R%3BMazurek%2C+Monica+A%3BLi%2C+Min%3BAlter%2C+Lee%3BGraham%2C+John%3BFelton%2C+H+Dirk%3BMcKenna%2C+Thomas%3BPietarinen%2C+Charles%3BLeston%2C+Alan%3BBailey%2C+Steve%3BArgao%2C+Sania+W+Tong&rft.aulast=McDow&rft.aufirst=Stephen&rft.date=2008-01-01&rft.volume=42&rft.issue=1&rft.spage=50&rft.isbn=&rft.btitle=&rft.title=Aerosol+Science+%26+Technology&rft.issn=02786826&rft_id=info:doi/10.1080%2F02786820701787936 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA, New York, New York City; USA, New Jersey; USA, Connecticut; Filters; Urban areas; Travel; Particle size; Particulates; Aerosols; Chemical speciation; Carboxylic acids; upstream; abundance; Sensitivity; Flow rates; Urban atmospheric pollution; Particulate matter in urban air; Atmospheric pollution; Organic compounds in atmosphere DO - http://dx.doi.org/10.1080/02786820701787936 ER - TY - JOUR T1 - Occurrence, Synthesis, and Mammalian Cell Cytotoxicity and Genotoxicity of Haloacetamides: An Emerging Class of Nitrogenous Drinking Water Disinfection Byproducts AN - 20009331; 7988275 AB - The haloacetamides, a class of emerging nitrogenous drinking water disinfection byproduct (DBPs), were analyzed for their chronic cytotoxicity and for the induction of genomic DNA damage in Chinese hamster ovary cells. The rank order for cytotoxicity of 13 haloacetamides was DIAcAm > IAcAm > BAcAm > TBAcAm > BIAcAm > DBCAcAm > CIAcAm > BDCAcAm > DBAcAm > BCAcAm > CAcAm > DCAcAm > TCAcAm. The rank order of their genotoxicity was TBAcAm > DIAcAm [asymptotic to] IAcAm > BAcAm > DBCAcAm > BIAcAm > BDCAcAm > CIAcAm > BCAcAm > DBAcAm > CAcAm > TCAcAm. DCAcAm was not genotoxic. Cytotoxicity and genotoxicity were primarily determined by the leaving tendency of the halogens and followed the order I > Br >> Cl. With the exception of brominated trihaloacetamides, most of the toxicity rank order was consistent with structure-activity relationship expectations. For di- and trihaloacetamides, the presence of at least one good leaving halogen group (I or Br but not Cl) appears to be critical for significant toxic activity. Log P was not a factor for monohaloacetamides but may play a role in the genotoxicity of trihaloacetamides and possible activation of dihaloacetamides by intracellular GSH and -SH compounds. With the advent of the U.S. EPA Stage 2 DBP regulations, water utilities are considering the use of disinfectants that are alternatives to chlorine. The use of these alternative disinfectants will shift the distribution of DBP chemical classes. The emergence of new, highly toxic iodinated, nitrogenous DBPs, as illustrated by the discovery of bromoiodoacetamide as a new DBP, underscores the importance of comparative toxicity studies to assist in the overall goal of safer drinking water practice. JF - Environmental Science & Technology AU - Plewa, Michael J AU - Muellner, Mark G AU - Richardson, Susan D AU - Fasano, Francesca AU - Buettner, Katherine M AU - Woo, Yin-Tak AU - McKague, ABruce AU - Wagner, Elizabeth D AD - College of Agricultural, Consumer and Environmental Sciences, Department of Crop Sciences, University of Illinois at Urbana-Champaign, 1101 West Peabody Drive, Urbana, Illinois 61801, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Athens, Georgia 30605, Risk Assessment Division, Office of Pollution Prevention and Toxics, U.S. Environmental Protection Agency, Washington, DC 20460 Y1 - 2008 PY - 2008 DA - 2008 SP - 955 EP - 961 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 3 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Water Resources Abstracts KW - Byproducts KW - USA KW - Genotoxicity KW - Toxicity KW - P 2000:FRESHWATER POLLUTION KW - N 14820:DNA Metabolism & Structure KW - SW 3060:Water treatment and distribution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20009331?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Occurrence%2C+Synthesis%2C+and+Mammalian+Cell+Cytotoxicity+and+Genotoxicity+of+Haloacetamides%3A+An+Emerging+Class+of+Nitrogenous+Drinking+Water+Disinfection+Byproducts&rft.au=Plewa%2C+Michael+J%3BMuellner%2C+Mark+G%3BRichardson%2C+Susan+D%3BFasano%2C+Francesca%3BBuettner%2C+Katherine+M%3BWoo%2C+Yin-Tak%3BMcKague%2C+ABruce%3BWagner%2C+Elizabeth+D&rft.aulast=Plewa&rft.aufirst=Michael&rft.date=2008-01-01&rft.volume=42&rft.issue=3&rft.spage=955&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes071754h LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Genotoxicity; Toxicity; USA DO - http://dx.doi.org/10.1021/es071754h ER - TY - JOUR T1 - Pilot Plant Testing of Elemental Mercury Reemission from a Wet Scrubber AN - 19997992; 8019189 AB - This paper is to discuss the recent observations of elemental mercury (Hg super(0)) reemissions from a pilot-scale limestone wet scrubber. Simulated flue gas was generated by burning natural gas in a down-fired furnace and doped with 2000 ppm of sulfur dioxide (SO sub(2)). Mercuric chloride (HgCl sub(2)) solution was delivered to the scrubber at a controlled rate to simulate the absorption of ionized mercury (Hg super(2+)). Testing results have shown that, after Hg super(2+) was injected, elevated Hg super(0) concentrations were soon detected both in the scrubber effluent flue gas and the hold tank air, which reflected the occurrence of Hg super(0) reemissions in both places. When the HgCl sub(2) feed was stopped, the Hg super(0) reemission continued for more than 2 h. In addition, a significant Hg super(0) reemission was also detected outside the scrubber loop. In an attempt to understand the Hg super(0) reemission increase across the wet scrubber system under transient and steady states and to understand the underlying relationship with the mercury complexes retained in the wet scrubber system, a mercury reemission model was developed. With this model, it was found that the Hg super(0) reemission rate under the current testing conditions can be simulated by a first-order reaction, and only a portion of Hg.S(IV) complexes retained in the slurry were participating in the reemission reaction. JF - Energy & Fuels AU - Chang, John CS AU - Zhao, Yongxin AD - U.S. Environmental Protection Agency, National Risk Management Research Laboratory, Air Pollution Prevention and Control Division (MD-E305-03), Research Triangle Park, North Carolina 27711 Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 338 EP - 342 PB - American Chemical Society, [mailto:service@acs.org] VL - 22 IS - 1 SN - 0887-0624, 0887-0624 KW - Pollution Abstracts KW - Limestone KW - Chlorides KW - Flue gas KW - Air pollution control KW - Effluents KW - burning KW - Natural gas KW - Sulfur dioxide KW - Furnaces KW - Slurries KW - Scrubbers KW - Absorption KW - Mercury KW - Pollution control equipment KW - Feeds KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19997992?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Energy+%26+Fuels&rft.atitle=Pilot+Plant+Testing+of+Elemental+Mercury+Reemission+from+a+Wet+Scrubber&rft.au=Chang%2C+John+CS%3BZhao%2C+Yongxin&rft.aulast=Chang&rft.aufirst=John&rft.date=2008-01-01&rft.volume=22&rft.issue=1&rft.spage=338&rft.isbn=&rft.btitle=&rft.title=Energy+%26+Fuels&rft.issn=08870624&rft_id=info:doi/10.1021%2Fef700355q LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Limestone; Flue gas; Chlorides; Air pollution control; burning; Effluents; Natural gas; Sulfur dioxide; Furnaces; Scrubbers; Slurries; Absorption; Mercury; Pollution control equipment; Feeds DO - http://dx.doi.org/10.1021/ef700355q ER - TY - JOUR T1 - Comparative Absorption and Bioaccumulation of Polybrominated Diphenyl Ethers following Ingestion via Dust and Oil in Male Rats AN - 19883778; 8133778 AB - Household dust has been implicated as a major source of polybrominated diphenyl ether (PBDE) exposure in humans. This finding has important implications for young children, who tend to ingest more dust than adults and may be more susceptible to some of the putative developmental effects of PBDEs. Absorption parameters of PBDEs from ingested dust are unknown; therefore, the objectives of this study were to determine and to compare the uptake of PBDEs from either household dust (NIST Standard Reference Material 2585) or a corn oil solution. Male rats were administered dust or corn oil doses at 1 or 6 mu g of PBDEs kg super(-1) body wt in the diet for 21 days (n = 4 rats per group). The concentrations of 15 PBDEs were measured in adipose tissue and liver from each treatment group and showed that bioconcentration was congener dependent, but for the majority of congeners, the concentrations did not differ with either dose level or dose vehicle. Hepatic Cyp2b1 and 2b2 mRNA expression increased in rats receiving the higher PBDE doses, suggesting potential effects on metabolic activity. Retention of PBDEs in tissues ranged from <5% of the dose for BDE-209 to 70% for BDEs-47, 100, and 153 but generally did not differ between the high dust and high oil treatment groups. Excretion via the feces was significantly lower in the high oil dosed rats suggesting differences in absorption, excretion, and/or metabolism. The present study shows that PBDEs in dust are readily bioavailable and are biologically active, as indicated by increased transcription of hepatic enzymes. JF - Environmental Science & Technology AU - Birnbaum, Linda S AU - Richardson, Vicki AU - Smith, David J AU - Hakk, Heldur AU - Diliberto, Janet J AU - Stapleton, Heather M AU - Huwe, Janice K AD - United States Department of Agriculture (USDA), Agricultural Research Service (ARS) Biosciences Research Laboratory, Fargo, North Dakota 58105, United States Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Experimental Toxicology Division, Research Triangle Park, North Carolina Y1 - 2008 PY - 2008 DA - 2008 SP - 2694 EP - 2700 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 7 SN - 0013-936X, 0013-936X KW - Toxicology Abstracts KW - Diets KW - Enzymes KW - Transcription KW - Children KW - Dust KW - Gene expression KW - Oil KW - polybrominated diphenyl ethers KW - Bioaccumulation KW - Liver KW - Adipose tissue KW - Congeners KW - Excretion KW - Feces KW - Metabolism KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19883778?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Comparative+Absorption+and+Bioaccumulation+of+Polybrominated+Diphenyl+Ethers+following+Ingestion+via+Dust+and+Oil+in+Male+Rats&rft.au=Birnbaum%2C+Linda+S%3BRichardson%2C+Vicki%3BSmith%2C+David+J%3BHakk%2C+Heldur%3BDiliberto%2C+Janet+J%3BStapleton%2C+Heather+M%3BHuwe%2C+Janice+K&rft.aulast=Birnbaum&rft.aufirst=Linda&rft.date=2008-01-01&rft.volume=42&rft.issue=7&rft.spage=2694&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes702644k LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-05-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Diets; Transcription; Enzymes; Children; Dust; Oil; Gene expression; polybrominated diphenyl ethers; Bioaccumulation; Liver; Congeners; Adipose tissue; Excretion; Feces; Metabolism DO - http://dx.doi.org/10.1021/es702644k ER - TY - JOUR T1 - Influence of Trophic Position and Spatial Location on Polychlorinated Biphenyl (PCB) Bioaccumulation in a Stream Food Web AN - 19875640; 8133719 AB - We tested the ability of delta super(15)N-derived trophic position (TP) to predict polychlorinated biphenyl (PCB) concentrations in a historically contaminated stream (Twelvemile Creek, SC). We analyzed sediment, four types of organic matter, 27 macroinvertebrate taxa, and 25 fish species from six sites spanning 25 stream km. [sigma]PCBs were high across sites (mean fish = 2505 ng g super(-1) wet), with little spatial variation in concentrations within a trophic level. [sigma]PCBs (wet weight) were significantly positively correlated with TP (r super(2) = 0.56) and lipids (r super(2) = 0.44), and concentrations increased 1-2 orders of magnitude among trophic levels. After adjusting for lipids, we calculated a food web magnification factor of 1.6 for [sigma]PCBs, which is low compared to marine and lentic food webs. The predictive power of TP for individual congeners increased with K sub(ow) (octanol-water partition coefficient), with regression slope similar to 0.48 and r super(2) similar to 0.70 for K sub(ow) > 6.5. The proportion of high K sub(ow) compounds increased with distance from the source and with trophic position. Spatial variation in congener patterns was high, in contrast to marine and lentic systems where variation is typically low. JF - Environmental Science & Technology AU - Johnson, Brent R AU - Walters, David M AU - Fritz, Ken M AU - Lazorchak, James M AU - McCormick, Frank H AD - National Exposure Research Laboratory, U.S. Environmental Protection Agency, 26 W. MLK Blvd., Cincinnati, Ohio 45268 Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 2316 EP - 2322 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 7 SN - 0013-936X, 0013-936X KW - Toxicology Abstracts; Pollution Abstracts; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts KW - Prediction KW - Historical account KW - Polychlorinated Biphenyls KW - Lipids KW - Pollution effects KW - taxa KW - Streams KW - Spatial variations KW - spatial distribution KW - Food Chains KW - spatial variations KW - Organic Matter KW - Congeners KW - Slopes KW - food webs KW - PCB compounds KW - PCB KW - Food webs KW - Sediment pollution KW - Sediment chemistry KW - Organic matter KW - octanol-water partition coefficients KW - Sediments KW - Trophic levels KW - Trophic Level KW - polychlorinated biphenyls KW - Bioaccumulation KW - Fish KW - Zoobenthos KW - O 4020:Pollution - Organisms/Ecology/Toxicology KW - P 1000:MARINE POLLUTION KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19875640?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Influence+of+Trophic+Position+and+Spatial+Location+on+Polychlorinated+Biphenyl+%28PCB%29+Bioaccumulation+in+a+Stream+Food+Web&rft.au=Johnson%2C+Brent+R%3BWalters%2C+David+M%3BFritz%2C+Ken+M%3BLazorchak%2C+James+M%3BMcCormick%2C+Frank+H&rft.aulast=Johnson&rft.aufirst=Brent&rft.date=2008-01-01&rft.volume=42&rft.issue=7&rft.spage=2316&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes0715849 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Prediction; Spatial variations; Sediment chemistry; Bioaccumulation; Organic matter; Pollution effects; Zoobenthos; Trophic levels; Food webs; PCB; spatial variations; polychlorinated biphenyls; Lipids; Congeners; octanol-water partition coefficients; Streams; Sediments; Historical account; Sediment pollution; spatial distribution; taxa; PCB compounds; food webs; Trophic Level; Food Chains; Organic Matter; Polychlorinated Biphenyls; Fish; Slopes DO - http://dx.doi.org/10.1021/es0715849 ER - TY - JOUR T1 - U.S. Regulation of the Effects of Sound on Marine Life: Noaa's Mandates and Use of Scientific Information AN - 19801965; 8852778 AB - Within the United States, the Marine Mammal Protection Act of 1972 and the Endangered Species Act of 1973 prohibit purposeful or incidental "take" of numerous marine, coastal, and anadromous species. These two statutes give the National Oceanic and Atmospheric Administration (NOAA) a mandate and the authority to protect numerous species of marine mammals, sea turtles, marine and anadromous fish, molluscs, and coral from activities conducted by government agencies, corporations, academic institutions, and private individuals. This paper summarizes the primary approaches NOAA uses to assess the effects of sound on these aquatic species and to regulate those effects based on the scientific evidence available. JF - Bioacoustics AU - Southall, B AU - Johnson, C AU - Scholik, A AU - Adams, T AU - Harrison, J AU - Hollingshead, K AD - National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Office of Science and Technology, Ocean Acoustics Program, 1315 East-West Highway SSMC3, Silver Spring, MD 20910, USA, brandon.southall@noaa.gov Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 275 EP - 278 VL - 17 IS - 1-3 SN - 0952-4622, 0952-4622 KW - Mollusks KW - Animal Behavior Abstracts; Ecology Abstracts; Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts KW - Marine KW - Acoustics KW - Anadromous species KW - Aquatic reptiles KW - turtles KW - Ecosystem disturbance KW - USA KW - anadromous species KW - Coral reefs KW - Marine mammals KW - Legal aspects KW - marine mammals KW - Coral KW - Endangered species KW - Marine molluscs KW - Corals KW - Governments KW - Mollusca KW - Government agencies KW - Bioacoustics KW - Noise (sound) KW - Y 25040:Behavioral Ecology KW - Q5 08523:Conservation, wildlife management and recreation KW - Q2 09123:Conservation KW - O 4090:Conservation and Environmental Protection KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08423:Behaviour UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19801965?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioacoustics&rft.atitle=U.S.+Regulation+of+the+Effects+of+Sound+on+Marine+Life%3A+Noaa%27s+Mandates+and+Use+of+Scientific+Information&rft.au=Southall%2C+B%3BJohnson%2C+C%3BScholik%2C+A%3BAdams%2C+T%3BHarrison%2C+J%3BHollingshead%2C+K&rft.aulast=Southall&rft.aufirst=B&rft.date=2008-01-01&rft.volume=17&rft.issue=1-3&rft.spage=275&rft.isbn=&rft.btitle=&rft.title=Bioacoustics&rft.issn=09524622&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-01-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Legal aspects; Anadromous species; Marine mammals; Aquatic reptiles; Coral; Marine molluscs; Governments; Ecosystem disturbance; Noise (sound); Endangered species; Corals; Bioacoustics; anadromous species; Acoustics; Coral reefs; marine mammals; turtles; Government agencies; Mollusca; USA; Marine ER - TY - JOUR T1 - Marine Mammal Noise-Exposure Criteria: Initial Scientific Recommendations AN - 19796978; 8852777 AB - A panel of experts from behavioral, physiological, and physical disciplines in acoustic research was convened to review the expanding literature on marine mammal (cetacean and pinniped) hearing and behavioral responses to sound and predict exposure levels above which adverse effects are expected. Two effect categories were considered: injury and behavioral disturbance. Proposed criteria for these effects were segregated according to categories of functional hearing types of major species groups and exposure types. The panel achieved many of its objectives but acknowledges limitations in the criteria because of sparseness or absence of critical data. JF - Bioacoustics AU - Southall, B L AU - Bowles, A E AU - Ellison, W T AU - Finneran, J J AU - Gentry, R L AU - Greene, CR Jr AU - Kastak, D AU - Ketten AU - Miller, J H AU - Nachtigall, P E AU - Richardson, W J AU - Thomas, JA AU - Tyack, P L AD - National Oceanic and Atmospheric Administration (NOAA), National Marine Fisheries Service, Office of Science and Technology, Marine Ecosystems Division, Ocean Acoustics Program, 1315 East-West Highway, Silver Spring, MD 20910-6233, USA, Brandon.Southall@noaa.gov Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 273 EP - 274 VL - 17 IS - 1-3 SN - 0952-4622, 0952-4622 KW - Cetaceans KW - Pinnipeds KW - Animal Behavior Abstracts; Ecology Abstracts; ASFA Marine Biotechnology Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts KW - Marine KW - Data processing KW - Injuries KW - Acoustics KW - Behaviour KW - Pinnipedia KW - Man-induced effects KW - Ecosystem disturbance KW - Reviews KW - Marine mammals KW - Sound KW - Cetacea KW - Hearing KW - Side effects KW - Bioacoustics KW - Noise (sound) KW - Y 25040:Behavioral Ecology KW - D 04040:Ecosystem and Ecology Studies KW - O 4080:Pollution - Control and Prevention KW - Q1 08423:Behaviour KW - Q5 08521:Mechanical and natural changes KW - Q4 27720:Technology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19796978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioacoustics&rft.atitle=Marine+Mammal+Noise-Exposure+Criteria%3A+Initial+Scientific+Recommendations&rft.au=Southall%2C+B+L%3BBowles%2C+A+E%3BEllison%2C+W+T%3BFinneran%2C+J+J%3BGentry%2C+R+L%3BGreene%2C+CR+Jr%3BKastak%2C+D%3BKetten%3BMiller%2C+J+H%3BNachtigall%2C+P+E%3BRichardson%2C+W+J%3BThomas%2C+JA%3BTyack%2C+P+L&rft.aulast=Southall&rft.aufirst=B&rft.date=2008-01-01&rft.volume=17&rft.issue=1-3&rft.spage=273&rft.isbn=&rft.btitle=&rft.title=Bioacoustics&rft.issn=09524622&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-01-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Injuries; Marine mammals; Behaviour; Man-induced effects; Ecosystem disturbance; Noise (sound); Data processing; Acoustics; Reviews; Sound; Hearing; Side effects; Bioacoustics; Pinnipedia; Cetacea; Marine ER - TY - JOUR T1 - Assessing The Health Effects and Risks Associated with Children's Inhalation Exposures--Asthma and Allergy AN - 19790688; 8024673 AB - Adults and children may have different reactions to inhalation exposures due to differences in target tissue doses following similar exposures, and/or different stages in lung growth and development. In the case of asthma and allergy both the developing immune system and initial encounters with common allergens contribute to this differential susceptibility. Asthma, the most common chronic childhood disease, has significant public health impacts and is characterized by chronic lung inflammation, reversible airflow obstruction, and immune sensitization to allergens. Animal studies described here suggest that air pollutants exacerbate asthma symptoms and may also play a role in disease induction. Changes characteristic of asthma were observed in rhesus monkeys sensitized to house dust mite antigen (HDMA) as infants and exposed repeatedly thereafter to ozone (O sub(3)) and HDMA. O sub(3) exposure compromised airway growth and development and exacerbated the allergen response to favor intermittent airway obstruction and wheeze. In Brown Norway rats a variety of air pollutants enhanced sensitization to HDMA such that symptoms elicited in response to subsequent allergen challenge were more severe. Although useful for assessing air pollutants effects on initial sensitization, the rodent immune system is immature at birth relative to humans, making this model less useful for studying differential effects between adults and children. Because computational models available to address children's inhalation exposures are limited, default adjustments and their associated uncertainty will continue to be used in children's inhalation risk assessment. Because asthma is a complex (multiple genes, phenotypes, organ systems) disease, this area is ripe for systems biology approaches. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Selgrade, MJK AU - Plopper, C G AU - Gilmour, MI AU - Conolly, R B AU - Foos, BSP AD - MD-B143-01, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA, selgrade.maryjane@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 196 EP - 207 VL - 71 IS - 3-4 SN - 1528-7394, 1528-7394 KW - House dust mite KW - Rhesus macaque KW - Rhesus monkey KW - Entomology Abstracts; Pollution Abstracts; Risk Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts; Immunology Abstracts KW - Inhalation KW - Risk assessment KW - immune system KW - Immune system KW - Animal models KW - Respiratory diseases KW - Development KW - Allergies KW - Public health KW - Rats KW - air flow KW - Hypersensitivity KW - Pollutants KW - Allergens KW - Macaca mulatta KW - Dermatophagoides pteronyssinus KW - Ozone KW - Respiratory tract KW - Mathematical models KW - Asthma KW - Children KW - Organs KW - Inflammation KW - Air pollution KW - Birth KW - House dust KW - Lung KW - Mites KW - Norway KW - rodents KW - Infants KW - F 06925:Hypersensitivity KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health KW - Z 05330:Reproduction and Development KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19790688?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Assessing+The+Health+Effects+and+Risks+Associated+with+Children%27s+Inhalation+Exposures--Asthma+and+Allergy&rft.au=Selgrade%2C+MJK%3BPlopper%2C+C+G%3BGilmour%2C+MI%3BConolly%2C+R+B%3BFoos%2C+BSP&rft.aulast=Selgrade&rft.aufirst=MJK&rft.date=2008-01-01&rft.volume=71&rft.issue=3-4&rft.spage=196&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390701597897 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Inhalation; Mathematical models; Immune system; Animal models; Asthma; Development; Children; Inflammation; Public health; Birth; Hypersensitivity; Pollutants; Lung; Allergens; Respiratory tract; Infants; Ozone; immune system; Respiratory diseases; Organs; Allergies; Rats; Air pollution; air flow; House dust; Mites; rodents; Macaca mulatta; Dermatophagoides pteronyssinus; Norway DO - http://dx.doi.org/10.1080/15287390701597897 ER - TY - JOUR T1 - Trends in total Vibrio spp. and Vibrio vulnificus concentrations in the eutrophic Neuse River Estuary, North Carolina, during storm events AN - 19755782; 8564711 AB - Vibrio spp. are ubiquitous members of aquatic microbial food webs that can be pathogenic to humans and a range of other organisms. Previously published predictive models for Vibrio spp. concentrations in estuarine and coastal waters, based only on salinity and temperature, are 70 to 75% accurate during 'normal' conditions (e.g. not during storms or drought). We have conducted a preliminary comparison of the output from this type of model to the natural concentrations of both total Vibrio spp. and the potentially pathogenic Vibrio vulnificus when measured during tropical storms. Water samples were collected in situ from a deployed platform in the Neuse River Estuary (NRE), North Carolina, USA, during 2 storm events: Hurricane Ophelia and Tropical Storm Ernesto. Total Vibrio spp. concentrations were measured using culture-based methods and V. vulnificus levels were determined using a newly developed, rapid quantitative polymerase chain reaction (QPCR) assay. Results were analyzed in relation to environmental parameters and to concentrations of the fecal indicator bacteria Escherichia coli (EC) and Enterococcus spp. (ENT). Total concentrations of Vibrio spp. in the NRE were often orders of magnitude higher than those predicted by a previously published model. These large deviations from model predictions may indicate contributions from storm forcing (e.g. resuspension, surges) that are missing from the calm weather observations used to build these models. JF - Aquatic Microbial Ecology AU - Wetz, Jennifer J AU - Blackwood, ADenene AU - Fries, JStephen AU - Williams, Zachary F AU - Noble, Rachel T AD - Institute of Marine Science, University of North Carolina-Chapel Hill, 3431 Arendell Street, Morehead City, North Carolina 28557, USA super(2)United States Environmental Protection Agency, 1300 Pennsylvania Ave NW, Washington, DC 20005, USA, rtnoble@email.unc.edu Y1 - 2008 PY - 2008 DA - 2008 SP - 141 EP - 149 PB - Inter-Research, Nordbuente 23 Oldendorf/Luhe 21385 Germany, [mailto:ir@int-res.com], [URL:http://www.int-res.com/] VL - 53 IS - 1 SN - 0948-3055, 0948-3055 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA Aquaculture Abstracts; Microbiology Abstracts B: Bacteriology; Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Vibrio spp. KW - Vibrio vulnificus KW - Storm events KW - Sediment resuspension KW - Neuse River Estuary KW - Water-born pathogens KW - Quantitative polymerase chain reaction KW - QPCR KW - Water Analysis KW - Nucleotide sequence KW - Storms KW - Models KW - Salinity effects KW - Escherichia coli KW - Polymerase chain reaction KW - Biological pollutants KW - Droughts KW - Weather forecasting KW - Food webs KW - Rivers KW - Temperature effects KW - Marine KW - ANW, USA, North Carolina KW - Weather KW - Pathogenic bacteria KW - ANW, USA, North Carolina, Neuse Estuary KW - Estuaries KW - Surges KW - Temperature KW - Brackish KW - Coastal waters KW - Tropical depressions KW - Model Studies KW - Hurricanes KW - Vibrio KW - Enterococcus KW - Microorganisms KW - Marine aquaculture KW - AQ 00001:Water Resources and Supplies KW - SW 0835:Streamflow and runoff KW - D 04040:Ecosystem and Ecology Studies KW - Q5 08504:Effects on organisms KW - Q1 08587:Diseases of Cultured Organisms KW - O 5060:Aquaculture KW - Q3 08587:Diseases of Cultured Organisms KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19755782?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Microbial+Ecology&rft.atitle=Trends+in+total+Vibrio+spp.+and+Vibrio+vulnificus+concentrations+in+the+eutrophic+Neuse+River+Estuary%2C+North+Carolina%2C+during+storm+events&rft.au=Wetz%2C+Jennifer+J%3BBlackwood%2C+ADenene%3BFries%2C+JStephen%3BWilliams%2C+Zachary+F%3BNoble%2C+Rachel+T&rft.aulast=Wetz&rft.aufirst=Jennifer&rft.date=2008-01-01&rft.volume=53&rft.issue=1&rft.spage=141&rft.isbn=&rft.btitle=&rft.title=Aquatic+Microbial+Ecology&rft.issn=09483055&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - Pathogenic bacteria; Salinity effects; Nucleotide sequence; Surges; Estuaries; Biological pollutants; Marine aquaculture; Weather forecasting; Tropical depressions; Temperature effects; Rivers; Hurricanes; Weather; Polymerase chain reaction; Coastal waters; Droughts; Storms; Food webs; Models; Vibrio; Water Analysis; Temperature; Microorganisms; Model Studies; Vibrio vulnificus; Enterococcus; Escherichia coli; ANW, USA, North Carolina; ANW, USA, North Carolina, Neuse Estuary; Marine; Brackish ER - TY - JOUR T1 - Human impacts on open ocean mercury concentrations AN - 19677425; 7891523 AB - We develop an empirically constrained multicompartment box model for mercury cycling in open ocean regions to investigate changes in concentrations resulting from anthropogenic perturbations of the global mercury cycle. Using Monte Carlo simulations, we explicitly consider the effects of variability in measured parameters on modeled seawater concentrations. Our simulations show that anthropogenic enrichment in all surface (25%) and deep ocean waters (11%) is lower than global atmospheric enrichment (300-500%) and varies considerably among geographic regions, ranging from >60% in parts of the Atlantic and Mediterranean to -1% in the deep Pacific. Model results indicate that open ocean mercury concentrations do not rapidly equilibrate with atmospheric deposition and on average will increase if anthropogenic emissions remain at their present level. We estimate the temporal lag between changes in atmospheric deposition and ocean mercury concentrations will vary from decades in most of the Atlantic up to centuries in parts of the Pacific. JF - Global Biogeochemical Cycles AU - Sunderland, Elsie M AU - Mason, Robert P AD - U.S. Environmental Protection Agency, Office of Research and Development, Boston, Massachusetts, USA Y1 - 2008/01// PY - 2008 DA - January 2008 PB - American Geophysical Union, 2000 Florida Ave., N.W. Washington DC 20009 USA, [mailto:service@agu.org] VL - 21 IS - 4 SN - 0886-6236, 0886-6236 KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Oceanic Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Ecology Abstracts; Toxicology Abstracts KW - Citation No. GB4022 KW - air-sea exchange KW - mercury KW - ocean KW - preindustrial KW - rivers KW - uncertainty. KW - 4255 Oceanography: General: Numerical modeling (0545 KW - 0560) KW - 4251 Oceanography: General: Marine pollution (0345 KW - 0478) KW - 4260 Oceanography: General: Ocean data assimilation and reanalysis (3225) KW - 0312 Atmospheric Composition and Structure: Air/sea constituent fluxes (3339 KW - 4504). KW - Monte Carlo simulation KW - Seawater KW - Mercury in seawater KW - Anthropogenic factors KW - Statistical analysis KW - Monte Carlo method KW - Mercury cycle KW - Models KW - Human impact KW - Marine environment KW - I, Pacific KW - Emissions KW - Mercury in the atmosphere KW - Atmospheric pollution KW - Biogeochemistry KW - Simulation KW - A, Atlantic KW - Pollutant deposition KW - Numerical simulations KW - MED KW - Oceans KW - Mercury KW - Human factors KW - Q5 08503:Characteristics, behavior and fate KW - P 0000:AIR POLLUTION KW - M2 551.463/.464:Seawater Properties (551.463/.464) KW - D 04040:Ecosystem and Ecology Studies KW - X 24360:Metals KW - Q2 09244:Air-sea coupling KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19677425?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+Biogeochemical+Cycles&rft.atitle=Human+impacts+on+open+ocean+mercury+concentrations&rft.au=Sunderland%2C+Elsie+M%3BMason%2C+Robert+P&rft.aulast=Sunderland&rft.aufirst=Elsie&rft.date=2008-01-01&rft.volume=21&rft.issue=4&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Global+Biogeochemical+Cycles&rft.issn=08866236&rft_id=info:doi/10.1029%2F2006GB002876 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Biogeochemistry; Statistical analysis; Anthropogenic factors; Mercury; Monte Carlo simulation; Marine environment; Oceans; Human impact; Models; Mercury in the atmosphere; Atmospheric pollution; Numerical simulations; Mercury in seawater; Monte Carlo method; Mercury cycle; Pollutant deposition; Seawater; Emissions; Simulation; Human factors; MED; I, Pacific; A, Atlantic DO - http://dx.doi.org/10.1029/2006GB002876 ER - TY - JOUR T1 - Pilot-Scale Experimental and Theoretical Investigations into the Thermal Destruction of a Bacillus anthracis Surrogate Embedded in Building Decontamination Residue Bundles AN - 19645813; 8424236 AB - Bacillus anthracis (B. anthracis) spores were released through the U.S. mail system in 2001, highlighting the need to develop efficacious methods of decontaminating and disposing of materials contaminated with biological agents. Incineration of building decontamination residue is a disposal option for such material, although the complete inactivation of bacterial spores via this technique is not a certainty. Tests revealed that under some circumstances, Geobacillus stearothermophilus (G. stearothermophilus; a surrogate for B. anthracis) spores embedded in building materials remained active after 35 min in a pilot-scale incinerator and survived with internal material bundle temperatures reaching over 500 C. A model was also developed to predict survival of a bacterial spore population undergoing thermal treatment in an incinerator using the thermal destruction kinetic parameters obtained in a laboratory setting. The results of the pilot-scale incinerator experiments are compared to model predictions to assess the accuracy of the model. JF - Environmental Science & Technology AU - Wood, Joseph P AU - Griffin, Nicole AU - Kariher, Peter AU - Betancourt, Doris AU - Lemieux, Paul AD - United States Environmental Protection Agency, Mail Code E343-06, Research Triangle Park, North Carolina 27711 Y1 - 2008 PY - 2008 DA - 2008 SP - 5712 EP - 5717 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 15 SN - 0013-936X, 0013-936X KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology; Pollution Abstracts KW - inactivation KW - Temperature effects KW - Residues KW - Temperature KW - Construction materials KW - Decontamination KW - Survival KW - Air quality KW - Geobacillus KW - Bacillus anthracis KW - Models KW - USA KW - Kinetics KW - Incinerators KW - survival KW - Spores KW - P 0000:AIR POLLUTION KW - A 01450:Environmental Pollution & Waste Treatment KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19645813?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Pilot-Scale+Experimental+and+Theoretical+Investigations+into+the+Thermal+Destruction+of+a+Bacillus+anthracis+Surrogate+Embedded+in+Building+Decontamination+Residue+Bundles&rft.au=Wood%2C+Joseph+P%3BGriffin%2C+Nicole%3BKariher%2C+Peter%3BBetancourt%2C+Doris%3BLemieux%2C+Paul&rft.aulast=Wood&rft.aufirst=Joseph&rft.date=2008-01-01&rft.volume=42&rft.issue=15&rft.spage=5712&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes7021945 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-09-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Kinetics; Survival; Decontamination; Incinerators; Spores; Models; inactivation; Residues; Temperature; Construction materials; Air quality; survival; Geobacillus; Bacillus anthracis; USA DO - http://dx.doi.org/10.1021/es7021945 ER - TY - JOUR T1 - Modeling the Toxicokinetics of Inhaled Toluene in Rats: Influence of Physical Activity and Feeding Status AN - 19603079; 8024679 AB - Toluene is found in petroleum-based fuels and used as a solvent in consumer products and industrial applications. The critical effects following inhalation exposure involve the brain and nervous system in both humans and experimental animals, whether exposure duration is acute or chronic. The goals of this physiologically based pharmacokinetic (PBPK) model development effort were twofold: (1) to evaluate and explain the influence of feeding status and activity level on toluene pharmacokinetics utilizing our own data from toluene-exposed Long Evans (LE) rats, and (2) to evaluate the ability of the model to simulate data from the published literature and explain differing toluene kinetics. Compartments in the model were lung, slowly and rapidly perfused tissue groups, fat, liver, gut, and brain; tissue transport was blood-flow limited and metabolism occurred in the liver. Chemical-specific parameters and initial organ volumes and blood flow rates were obtained from the literature. Sensitivity analysis revealed that the single most influential parameter for our experimental conditions was alveolar ventilation; other moderately influential parameters (depending upon concentration) included cardiac output, rate of metabolism, and blood flow to fat Based on both literature review and sensitivity analysis, other parameters (e.g., partition coefficients and metabolic rate parameters) were either well defined (multiple consistent experimental results with low variability) or relatively noninfluential (e.g. organ volumes). Rats that were weight-maintained compared to free-fed rats in our studies could be modeled with a single set of parameters because feeding status did not have a significant impact on toluene pharmacokinetics. Heart rate (HR) measurements in rats performing a lever-pressing task indicated that the HR increased in proportion to task intensity. For rats acclimated to eating in the lab during the day, both sedentary rats and rats performing the lever-pressing task required different alveolar ventilation rates to successfully predict the data. Model evaluation using data from diverse sources together with statistical evaluation of the resulting fits revealed that the model appropriately predicted blood and brain toluene concentrations with some minor exceptions. These results (1) emphasize the importance of experimental conditions and physiological status in explaining differing kinetic data, and (2) demonstrate the need to consider simulation conditions when estimating internal dose metrics for toxicity studies in which kinetic data were not collected. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Kenyon, E M AU - Benignus, V AU - Eklund, C AU - Highfill, J W AU - Oshiro, WM AU - Samsam, TE AU - Bushnell, P J AD - Experimental Toxicology Division, B143-01, U.S. Environmental Protection Agency, Research Tiangle Park, NC 27711, USA, kenyon.elaina@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 249 EP - 265 VL - 71 IS - 3-4 SN - 1528-7394, 1528-7394 KW - Toxicology Abstracts KW - Inhalation KW - Statistics KW - Ventilation KW - Toluene KW - Physical activity KW - Fuels KW - Heart rate KW - Statistical analysis KW - Metabolic rate KW - Models KW - Nervous system KW - Consumers KW - Feeding KW - Brain KW - Solvents KW - Toxicity KW - Alveoli KW - Pharmacokinetics KW - Digestive tract KW - Industrial applications KW - Lung KW - Kinetics KW - Reviews KW - Liver KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19603079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Modeling+the+Toxicokinetics+of+Inhaled+Toluene+in+Rats%3A+Influence+of+Physical+Activity+and+Feeding+Status&rft.au=Kenyon%2C+E+M%3BBenignus%2C+V%3BEklund%2C+C%3BHighfill%2C+J+W%3BOshiro%2C+WM%3BSamsam%2C+TE%3BBushnell%2C+P+J&rft.aulast=Kenyon&rft.aufirst=E&rft.date=2008-01-01&rft.volume=71&rft.issue=3-4&rft.spage=249&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390701528363 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Inhalation; Feeding; Statistics; Ventilation; Fuels; Physical activity; Toluene; Heart rate; Solvents; Metabolic rate; Brain; Statistical analysis; Toxicity; Pharmacokinetics; Alveoli; Models; Nervous system; Digestive tract; Industrial applications; Lung; Reviews; Kinetics; Liver; Consumers DO - http://dx.doi.org/10.1080/15287390701528363 ER - TY - JOUR T1 - Perfluoroalkyl Acids in the Egg Yolk of Birds from Lake Shihwa, Korea AN - 19577257; 8424253 AB - Concentrations of perfluoroalkyl acids (PFAs) were measured in egg yolks of three species of birds, the little egret (Egretta garzetta), little ringed plover (Charadrius dubius), and parrot bill (Paradoxornis webbiana), collected in and around Lake Shihwa, Korea, which receives wastewaters from an adjacent industrial complex. Mean concentrations of perfluorooctanesulfonate (PFOS) ranged from 185 to 314 ng/g ww and were similar to those reported for bird eggs from other urban areas. Long-chain perfluorocarboxylic acids (PFCAs) were also found in egg yolks often at great concentrations. Mean concentrations of perfluoroundecanoic acid (PFUnA) ranged from 95 to 201 ng/g ww. Perfluorooctanoic acid was detected in 32 of 44 egg samples, but concentrations were 100-fold less than those of PFOS. Relative concentrations of PFAs in all three species were similar with the predominance of PFOS (45-50%). There was a statistically significant correlation between PFUnA and perfluorodecanoic acid in egg yolks (p < 0.05), suggesting a common source of PFCAs. Using measured egg concentrations and diet concentrations, the ecological risk of the PFOS and PFA mixture to birds in Lake Shihwa was evaluated using two different approaches. Estimated hazard quotients were similar between the two approaches. The concentration of PFOS associated with 90th centile in bird eggs was 100-fold less than the lowest observable adverse effect level determined for birds, and those concentrations were 4-fold less than the suggested toxicity reference values. On the basis of limited toxicological data, current concentrations of PFOS are less than what would be expected to have an adverse effect on birds in the Lake Shihwa region. JF - Environmental Science & Technology AU - Lee, Kyu Tae AU - Kannan, Kurunthachalam AU - Kim, Seong Kyu AU - Newsted, John L AU - Giesy, John P AU - Yoo, Hoon AD - National Food Safety and Toxicology Center, Zoology Department and Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan 48824, U.S. EPA, National Exposure Research Laboratory, 960 College Station Road, Athens, Georgia 30605, Wadsworth Center, New York State Department of Health and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, Albany, New York 12201-0509, Institute of Environmental Protection and Safety, NeoEnbiz Co., Rm 1306, Bucheon Daewoo Technopark Bldg. A, Dodang dong 187-7, Bucheon, Gyeonggi, Korea, ENTRIX, Inc., 4295 Okemos Road, Suite 101, Okemos, Michigan 48864, Department of Biomedical and Veterinary Biosciences and Toxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 5821 EP - 5827 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 15 SN - 0013-936X, 0013-936X KW - ASFA 3: Aquatic Pollution & Environmental Quality; Pollution Abstracts; Water Resources Abstracts KW - Korea, Rep., Kyonggi-do, Shihwa L. KW - Bird eggs KW - Eggs KW - Yolk KW - Hazards KW - Lakes KW - Korea, Rep. KW - Urban areas KW - Diets KW - Charadrius dubius KW - Toxicity KW - Aves KW - Dominant species KW - Acids KW - Water Pollution Effects KW - Urban Areas KW - Egretta garzetta KW - Birds KW - Wastewater KW - bird eggs KW - Side effects KW - Aquatic birds KW - Q5 08503:Characteristics, behavior and fate KW - P 2000:FRESHWATER POLLUTION KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19577257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Perfluoroalkyl+Acids+in+the+Egg+Yolk+of+Birds+from+Lake+Shihwa%2C+Korea&rft.au=Lee%2C+Kyu+Tae%3BKannan%2C+Kurunthachalam%3BKim%2C+Seong+Kyu%3BNewsted%2C+John+L%3BGiesy%2C+John+P%3BYoo%2C+Hoon&rft.aulast=Lee&rft.aufirst=Kyu&rft.date=2008-01-01&rft.volume=42&rft.issue=15&rft.spage=5821&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes800447d LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Hazards; Dominant species; Toxicity; Eggs; Aquatic birds; Bird eggs; Yolk; Diets; Lakes; Side effects; bird eggs; Urban areas; Urban Areas; Water Pollution Effects; Acids; Birds; Wastewater; Aves; Charadrius dubius; Egretta garzetta; Korea, Rep., Kyonggi-do, Shihwa L.; Korea, Rep. DO - http://dx.doi.org/10.1021/es800447d ER - TY - JOUR T1 - CProb: A Computational Tool for Conducting Conditional Probability Analysis AN - 19556209; 8605104 AB - Conditional probability is the probability of observing one event given that another event has occurred. In an environmental context, conditional probability helps to assess the association between an environmental contaminant (i.e., the stressor) and the ecological condition of a resource (i.e., the response). These analyses, when combined with controlled experiments and other methodologies, show great promise in evaluating ecological conditions from observational data and in defining water quality and other environmental criteria. Current applications of conditional probability analysis (CPA) are largely done via scripts or cumbersome spreadsheet routines, which may prove daunting to end-users and do not provide access to the underlying scripts. Combining spreadsheets with scripts eases computation through a familiar interface (i.e., Microsoft Excel) and creates a transparent process through full accessibility to the scripts. With this in mind, we developed a software application, CProb, as an Add-in for Microsoft Excel with R, R(D)com Server, and Visual Basic for Applications. CProb calculates and plots scatterplots, empirical cumulative distribution functions, and conditional probability. In this short communication, we describe CPA, our motivation for developing a CPA tool, and our implementation of CPA as a Microsoft Excel Add-in. Further, we illustrate the use of our software with two examples: a water quality example and a landscape example. CProb is freely available for download at http://www.epa.gov/emap/nca/html/regions/cprob. JF - Journal of Environmental Quality AU - Hollister, Jeffrey W AU - Walker, Henry A AU - Paul, John F AD - U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Lab., Atlantic Ecology Div., 27 Tarzwell Drive, Narragansett, RI 02882, Hollister.jeff@epa.gov Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 2392 EP - 2396 PB - American Society of Agronomy, 677 South Segoe Rd Madison WI 53711 USA VL - 37 IS - 6 SN - 0047-2425, 0047-2425 KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - water quality KW - Computer programs KW - Communications KW - Landscape KW - Water quality KW - Environmental factors KW - Q5 08503:Characteristics, behavior and fate KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19556209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Quality&rft.atitle=CProb%3A+A+Computational+Tool+for+Conducting+Conditional+Probability+Analysis&rft.au=Hollister%2C+Jeffrey+W%3BWalker%2C+Henry+A%3BPaul%2C+John+F&rft.aulast=Hollister&rft.aufirst=Jeffrey&rft.date=2008-01-01&rft.volume=37&rft.issue=6&rft.spage=2392&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Quality&rft.issn=00472425&rft_id=info:doi/10.2134%2Fjeq2007.0536 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Water quality; Environmental factors; Computer programs; water quality; Communications; Landscape DO - http://dx.doi.org/10.2134/jeq2007.0536 ER - TY - JOUR T1 - Improved Estimates of Cancer Site-Specific Risks for A-Bomb Survivors AN - 19554553; 8693510 AB - Pawel, D. J., Preston, D. L., Pierce, D. A. and Cologne, J. B. Improved Estimates of Cancer Site-Specific Risks for A-Bomb Survivors. Radiat. Res. 169, 87-98 (2008). Simple methods are investigated for improving summary site-specific radiogenic risk estimates. Estimates in this report are derived from cancer incidence data from the Life Span Study (LSS) cohort of A-bomb survivors that are followed up by the Radiation Effects Research Foundation (RERF). Estimates from the LSS of excess relative risk (ERR) for solid cancer sites have typically been derived separately for each site. Even though the data for this are extensive, the statistical imprecision in site-specific (organ-specific) risk estimates is substantial, and it is clear that a large portion of the site-specific variation in estimates is due to this imprecision. Empirical Bayes (EB) estimates offer a reasonable approach for moderating this variation. The simple version of EB estimates that we applied to the LSS data are weighted averages of a pooled overall estimate of ERR and separately derived site-specific estimates, with weights determined by the data. Results indicate that the EB estimates are most useful for sites such as esophageal or bladder cancer, for which the separately derived ERR estimates are less precise than for other sites. JF - Radiation Research AU - Pawel, David AU - Preston, Dale AU - Pierce, Donald AU - Cologne, John AD - U.S. Environmental Protection Agency, Washington, D.C., pawel.david@epa.gov Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 87 EP - 98 PB - Allen Press, Inc., 810 East Tenth St. VL - 169 IS - 1 SN - 0033-7587, 0033-7587 KW - Toxicology Abstracts KW - Risk assessment KW - Esophagus KW - Data processing KW - Statistics KW - Urinary bladder KW - Bayesian analysis KW - Life span KW - Cancer KW - X 24390:Radioactive Materials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19554553?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiation+Research&rft.atitle=Improved+Estimates+of+Cancer+Site-Specific+Risks+for+A-Bomb+Survivors&rft.au=Pawel%2C+David%3BPreston%2C+Dale%3BPierce%2C+Donald%3BCologne%2C+John&rft.aulast=Pawel&rft.aufirst=David&rft.date=2008-01-01&rft.volume=169&rft.issue=1&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Radiation+Research&rft.issn=00337587&rft_id=info:doi/10.1667%2FRR1092.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Esophagus; Risk assessment; Statistics; Data processing; Bayesian analysis; Urinary bladder; Life span; Cancer DO - http://dx.doi.org/10.1667/RR1092.1 ER - TY - JOUR T1 - Pb isotopes in drinking water: A new strategy for source detection of low Pb sources AN - 19549151; 8681405 AB - Source detection of low concentrations of Pb in water, for instance less than 15 is a subset of g L-1, may require a new methodology as the tolerances of Pb in drinking water are further reduced. It appears that the isotope properties of Pb may aid discrimination among natural sources and anthropogenic sources, including some plumbing materials. Characteristic Pb isotope signatures in a typical rural water supply district, located in Maine, are outlined. For example, unflushed drinking water lines have 207Pb/206Pb (0.850) and 208Pb/206Pb (2.130) signatures similar to Pb solders on pipes with ages of 7-38 years. Whereas reduced Pb concentrations in drinking water lines correlate with naturally distinctive signatures of 207Pb/206Pb (0.785) and 208Pb/206Pb (1.945). JF - Environmental Sciences AU - Sidle, W C AU - Haught, R AD - U. S. Environmental Protection Agency, National Risk Management Research Laboratory, Water Supply & Water Resources Division, Cincinnati, OH, USA Y1 - 2008/01// PY - 2008 DA - Jan 2008 SP - 205 EP - 211 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 5 IS - 3 SN - 1569-3430, 1569-3430 KW - Pollution Abstracts; Water Resources Abstracts KW - Pipes KW - Isotopes KW - Age KW - discrimination KW - anthropogenic factors KW - Water Supply KW - Water supplies KW - Lead KW - Plumbing KW - Drinking Water KW - USA, Maine KW - Drinking water KW - Rural areas KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19549151?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Sciences&rft.atitle=Pb+isotopes+in+drinking+water%3A+A+new+strategy+for+source+detection+of+low+Pb+sources&rft.au=Sidle%2C+W+C%3BHaught%2C+R&rft.aulast=Sidle&rft.aufirst=W&rft.date=2008-01-01&rft.volume=5&rft.issue=3&rft.spage=205&rft.isbn=&rft.btitle=&rft.title=Environmental+Sciences&rft.issn=15693430&rft_id=info:doi/10.1080%2F15693430802149897 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Pipes; Age; Isotopes; discrimination; anthropogenic factors; Drinking water; Water supplies; Lead; Rural areas; Plumbing; Drinking Water; Water Supply; USA, Maine DO - http://dx.doi.org/10.1080/15693430802149897 ER - TY - JOUR T1 - Functionally charged polystyrene particles activate immortalized mouse microglia (BV2): cellular and genomic response AN - 19539341; 8493287 AB - The effect of particle surface charge on the biological activation of immortalized mouse microglia (BV2) was examined. Same size (6850-950 nm) spherical polystyrene microparticles (SPM) with net negative (carboxyl, COOH-) or positive (dimethyl amino, CH sub(3)) sub(2)-N-zeta potentials were exposed to BV2 microglia (5-20 kl/ml). Both stimulated an oxidative burst, increased Caspase 3/7 activity and caused inflammatory cytokine release. Ultrastructure indicated that SPM particles were phagocytosed as single particles but formed large intra-cellular 4-6 kn agglomerates. Microarray analysis indicated that negatively charged SPM-COOH-affected approximately 146 genes while the positively charged SPM-(CH sub(3)) sub(2)-N-affected approximately 2580 genes. Only 30 genes were significantly affected in common. Of the 48 genes associated with oxidative stress pathways, 33 genes were coordinately down-regulated by SPM-(CH sub(3)) sub(2)-N- and up-regulated by SPM-COOH-exposure. Together, these data indicate that functionally charged, inert submicron-size particles differentially activate BV2 microglia along oxidative stress and inflammatory pathways. JF - Nanotoxicology AU - Veronesi, B AU - Tajuba, J AU - Saleh, N AU - Ward, W AU - Hester, S AU - Carter, J AU - Lowry, G V AD - National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC, USA Y1 - 2008 PY - 2008 DA - 2008 SP - 130 EP - 143 VL - 2 IS - 3 SN - 1743-5390, 1743-5390 KW - Genetics Abstracts; Toxicology Abstracts KW - Data processing KW - microparticles KW - Oxidative stress KW - polystyrene KW - Caspase-3 KW - Cytokines KW - genomics KW - Surface charge KW - Microglia KW - Ultrastructure KW - Inflammation KW - G 07720:Immunogenetics KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19539341?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Functionally+charged+polystyrene+particles+activate+immortalized+mouse+microglia+%28BV2%29%3A+cellular+and+genomic+response&rft.au=Veronesi%2C+B%3BTajuba%2C+J%3BSaleh%2C+N%3BWard%2C+W%3BHester%2C+S%3BCarter%2C+J%3BLowry%2C+G+V&rft.aulast=Veronesi&rft.aufirst=B&rft.date=2008-01-01&rft.volume=2&rft.issue=3&rft.spage=130&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=17435390&rft_id=info:doi/10.1080%2F17435390802296347 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-10-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Data processing; microparticles; Oxidative stress; Caspase-3; polystyrene; Cytokines; Surface charge; genomics; Ultrastructure; Microglia; Inflammation DO - http://dx.doi.org/10.1080/17435390802296347 ER - TY - JOUR T1 - Organic Carbon-Water Concentration Quotients (II sub(soc)s and [pi] sub(poc)s): Measuring Apparent Chemical Disequilibria and Exploring the Impact of Black Carbon in Lake Michigan AN - 19535390; 8220713 AB - Chemical concentration quotients measured between water and total organic carbon (TOC) in sediment (II sub(soc)) or suspended particulates ([pi] sub(poc)) in southern Lake Michigan reveal up to 2 orders of magnitude differences for polychlorinated biphenyl (PCB), dibenzo-p-dioxin (PCDD), dibenzofuran (PCDF), and polycyclic aromatic hydrocarbon (PAH) compounds with similar octanol-water partition coefficients (K sub(ow)s). Apparent disequilibria for PAHs, PCDDs, and PCDFs, determined as measured II sub(soc)s or [pi] sub(poc)s divided by their organic carbon equilibrium partitioning values, are significantly greater than disequilibria of PCBs with similar K sub(ow)s. Apparent disequilibria, when adjusted for black carbon content by using published black carbon nonlinear partition coefficients (K sub(f,bc)s) and a Freundlich exponent (n sub(f)) value = 0.7, still exceed equilibrium predictions for the PAHs, PCBs, and PCDDs but with the PCDF disequilibria uniquely below equilibrium. While Monte Carlo analysis of all the variables associated with the black carbon adjusted disequilibria provides wide confidence intervals for individual chemicals, the large class disequilibria differences between PAHs and PCDFs with respect to the PCBs and PCDDs are highly significant. Use of the PCDD K sub(f,bc)s for calculating both the PCDF and PCDD disequilibria eliminates their extreme divergence. On the basis of the complexity of carbonaceous geosorbent effects and the apparent variable degrees of chemical sequestration in particles, the disequilibria can be adjusted by chemical class to meet expected near equilibrium conditions between suspended particles and water in the hypolimnion. Although these adjustments to the disequilibria calculations produce consistent and plausible values, the complexities of variable carbonaceous geosorbent affinities for these chemicals in Lake Michigan presently favor use of measured, rather than a priori modeled, steady-state total organic carbon- water concentration quotients indexed to TOC as biogenic organic carbon. JF - Environmental Science & Technology AU - Lukasewycz, Marta T AU - Burkhard, Lawrence P AU - Cook, Philip M AD - Mid-Continent Ecology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, 6201 Congdon Boulevard, Duluth, Minnesota 55804 Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 3615 EP - 3621 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 10 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts; Meteorological & Geoastrophysical Abstracts KW - Prediction KW - Monte Carlo simulation KW - Salinity variations KW - Polychlorinated Biphenyls KW - Hypolimnions KW - Organic carbon KW - Environmental sciences KW - Statistical analysis KW - Monte Carlo method KW - Particulates KW - Divergence KW - Freshwater KW - Resuspended sediments KW - Lakes KW - Carbon KW - black carbon KW - Total organic carbon KW - PCDF KW - Aromatic hydrocarbons KW - PCB compounds KW - PCDD KW - PCB KW - Hypolimnion KW - Sediment pollution KW - Polycyclic aromatic hydrocarbons KW - Suspended Sediments KW - hypolimnion KW - Polycyclic aromatic hydrocarbons in lake water KW - Organic Carbon KW - Suspended particulate matter KW - Model Studies KW - USA, Michigan KW - USA, Michigan L. KW - Equilibrium KW - polycyclic aromatic hydrocarbons KW - M2 556.55:Lakes, Reservoirs, Ponds (556.55) KW - Q2 09283:Soil mechanics KW - P 2000:FRESHWATER POLLUTION KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19535390?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Organic+Carbon-Water+Concentration+Quotients+%28II+sub%28soc%29s+and+%5Bpi%5D+sub%28poc%29s%29%3A+Measuring+Apparent+Chemical+Disequilibria+and+Exploring+the+Impact+of+Black+Carbon+in+Lake+Michigan&rft.au=Lukasewycz%2C+Marta+T%3BBurkhard%2C+Lawrence+P%3BCook%2C+Philip+M&rft.aulast=Lukasewycz&rft.aufirst=Marta&rft.date=2008-01-01&rft.volume=42&rft.issue=10&rft.spage=3615&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes702652b LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Resuspended sediments; Sediment pollution; Total organic carbon; Organic carbon; Statistical analysis; Aromatic hydrocarbons; Suspended particulate matter; Hypolimnion; PCB; Salinity variations; Polycyclic aromatic hydrocarbons in lake water; Hypolimnions; Environmental sciences; Monte Carlo method; Divergence; Monte Carlo simulation; hypolimnion; Particulates; Lakes; black carbon; PCDF; polycyclic aromatic hydrocarbons; PCB compounds; PCDD; Prediction; Suspended Sediments; Polycyclic aromatic hydrocarbons; Carbon; Equilibrium; Organic Carbon; Polychlorinated Biphenyls; Model Studies; USA, Michigan; USA, Michigan L.; Freshwater DO - http://dx.doi.org/10.1021/es702652b ER - TY - JOUR T1 - Binding of vapour-phase mercury (Hg super(0)) on chemically treated bauxite residues (red mud) AN - 19486431; 8566560 JF - Environmental Chemistry AU - Hutson, Nick D AU - Attwood, Brian C AD - Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA, hutson.nick@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 281 EP - 288 PB - CSIRO Publishing, PO Box 1139 150 Oxford Street Collingwood Vic. 3066 Australia, [mailto:publishing@csiro.au], [URL:http://www.publish.csiro.au/] VL - 5 IS - 4 SN - 1448-2517, 1448-2517 KW - Pollution Abstracts KW - Vapors KW - mud KW - Residues KW - Mercury KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19486431?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Chemistry&rft.atitle=Binding+of+vapour-phase+mercury+%28Hg+super%280%29%29+on+chemically+treated+bauxite+residues+%28red+mud%29&rft.au=Hutson%2C+Nick+D%3BAttwood%2C+Brian+C&rft.aulast=Hutson&rft.aufirst=Nick&rft.date=2008-01-01&rft.volume=5&rft.issue=4&rft.spage=281&rft.isbn=&rft.btitle=&rft.title=Environmental+Chemistry&rft.issn=14482517&rft_id=info:doi/10.1071%2FEN08026 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Vapors; Residues; Mercury; mud DO - http://dx.doi.org/10.1071/EN08026 ER - TY - JOUR T1 - Mercury Concentrations in Salmonids from Western U.S. National Parks and Relationships with Age and Macrophage Aggregates AN - 19477154; 8125975 AB - Mercury accumulation in aquatic foodwebs and its effects on aquatic biota are of growing concern both for the health of the fish and the piscivores that prey upon them. This is of particular concern for western U.S. National Parks because it is known that mountainous and Arctic areas are sinks for some contaminants. The Western Airborne Contaminants Assessment Project seeks, in part, to ascertain mercury concentrations and evaluate effects of contaminants on biota in 14 lakes from 8 National Parks or Preserves. In this paper we report that mercury has accumulated to concentrations in trout that may negatively impact some piscivorous wildlife, indicating potential terrestrial ecosystem effects. Additionally, we show that mercury concentrations increase with age in 4 species of trout, providing evidence of bioaccumulation. Finally, we demonstrate that mercury is associated with tissue damage in the kidney and spleen, as indicated by increases in macrophage aggregates. This finding suggests that mercury, and possibly other contaminants, are negatively affecting the trout that inhabit these remote and protected ecosystems. Our results indicate that mercury is indeed a concern for the U.S. National Parks, from an organismic and potentially an ecosystem perspective. JF - Environmental Science & Technology AU - Kent, Michael L AU - Landers, Dixon H AU - Schwindt, Adam R AU - Fournie, John W AU - Schreck, Carl B AD - Department of Microbiology, Center for Fish Disease Research, 220 Nash Hall, Oregon State University, Corvallis, Oregon 97331, Gulf Ecology Division, U.S. Environmental Protection Agency, Gulf Breeze, Florida, Western Ecology Division, U.S. Environmental Protection Agency, Corvallis, Oregon, Oregon Cooperative Fish and Wildlife Research Unit, U.S. Geological Survey, Corvallis, Oregon Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 1365 EP - 1370 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 4 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Toxicology Abstracts KW - Food organisms KW - Ecosystems KW - Anadromous species KW - national parks KW - Mountains KW - Biota KW - Lakes KW - National Parks KW - Salmonidae KW - Wildlife KW - prey KW - Kidneys KW - Aggregates KW - Trout KW - Water Pollution Effects KW - Mercury KW - terrestrial ecosystems KW - Contaminants KW - Macrophages KW - Age KW - Food KW - National parks KW - Pollution effects KW - Environmental factors KW - Pollutants KW - Assessments KW - Prey KW - Spleen KW - Polar environments KW - PN, Arctic KW - Air pollution KW - USA KW - Terrestrial ecosystems KW - Bioaccumulation KW - Kidney KW - P 2000:FRESHWATER POLLUTION KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19477154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Mercury+Concentrations+in+Salmonids+from+Western+U.S.+National+Parks+and+Relationships+with+Age+and+Macrophage+Aggregates&rft.au=Kent%2C+Michael+L%3BLanders%2C+Dixon+H%3BSchwindt%2C+Adam+R%3BFournie%2C+John+W%3BSchreck%2C+Carl+B&rft.aulast=Kent&rft.aufirst=Michael&rft.date=2008-01-01&rft.volume=42&rft.issue=4&rft.spage=1365&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes702337m LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Macrophages; Food organisms; Bioaccumulation; Anadromous species; Spleen; Mercury; Kidneys; Environmental factors; Aggregates; Age; Food; Wildlife; National parks; Lakes; Terrestrial ecosystems; Kidney; Contaminants; Prey; Ecosystems; Pollution effects; national parks; prey; Polar environments; Mountains; Air pollution; Biota; terrestrial ecosystems; Assessments; Pollutants; National Parks; Trout; Water Pollution Effects; Salmonidae; PN, Arctic; USA DO - http://dx.doi.org/10.1021/es702337m ER - TY - JOUR T1 - Atmospherically Deposited PBDEs, Pesticides, PCBs, and PAHs in Western U.S. National Park Fish: Concentrations and Consumption Guidelines AN - 19473828; 8133722 AB - Concentrations of polybrominated diphenyl ethers (PBDEs), pesticides, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons were measured in 136 fish from 14 remote lakes in 8 western U.S. National Parks/Preserves between 2003 and 2005 and compared to human and wildlife contaminant health thresholds. A sensitive (median detection limit, -18 pg/g wet weight), efficient (61% recovery at 8 ng/g), reproducible (4.1% relative standard deviation (RSD)), and accurate (7% deviation from standard reference material (SRM)) analytical method was developed and validated for these analyses. Concentrations of PCBs, hexachlorobenzene, hexachlorocyclohexanes, DDTs, and chlordanes in western U.S. fish were comparable to or lower than mountain fish recently collected from Europe, Canada, and Asia. Dieldrin and PBDE concentrations were higher than recent measurements in mountain fish and Pacific Ocean salmon. Concentrations of most contaminants in western U.S. fish were 1-6 orders of magnitude below calculated recreational fishing contaminant health thresholds. However, lake average contaminant concentrations in fish exceeded subsistence fishing cancer thresholds in 8 of 14 lakes and wildlife contaminant health thresholds for piscivorous birds in 1of 14 lakes. These results indicate that atmospherically deposited organic contaminants can accumulate in high elevation fish, reaching concentrations relevant to human and wildlife health. JF - Environmental Science & Technology AU - Landers, Dixon H AU - Massey Simonich, Staci L AU - Kent, Michael L AU - Blett, Tamara F AU - Koch, Dan C AU - Schwindt, Adam R AU - Schreck, Carl B AU - Ackerman, Luke K AD - Department of Chemistry, Department of Environmental and Molecular Toxicology, Oregon Cooperative Fish and Wildlife Research UnitU.S. Geological Survey, Department of Fisheries and Wildlife, Center for Fish Disease Research-Department of Microbiology; Oregon State University, Corvallis, Oregon 97331, United States National Park Service, Denver, Colorado 80225, United States Environmental Protection Agency, Corvallis, Oregon 97335 Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 2334 EP - 2341 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 42 IS - 7 SN - 0013-936X, 0013-936X KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts KW - Polychlorinated Biphenyls KW - Anadromous species KW - national parks KW - Pollution effects KW - Freshwater KW - Freshwater fish KW - Public health KW - Mountains KW - Lakes KW - Insecticides KW - Pollutants KW - guidelines KW - ANE, Europe KW - I, Pacific KW - INW, Asia KW - Aromatic hydrocarbons KW - Salmonidae KW - PCB compounds KW - PCB KW - Pollution detection KW - Wildlife KW - Dieldrin KW - Brominated hydrocarbons KW - Cancer KW - USA KW - polybrominated diphenyl ethers KW - Bioaccumulation KW - Recreation KW - Canada KW - Recreation areas KW - Water Pollution Effects KW - Oceans KW - hexachlorocyclohexane KW - Pesticides KW - DDT KW - Fish KW - Standards KW - fishing KW - P 1000:MARINE POLLUTION KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19473828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Atmospherically+Deposited+PBDEs%2C+Pesticides%2C+PCBs%2C+and+PAHs+in+Western+U.S.+National+Park+Fish%3A+Concentrations+and+Consumption+Guidelines&rft.au=Landers%2C+Dixon+H%3BMassey+Simonich%2C+Staci+L%3BKent%2C+Michael+L%3BBlett%2C+Tamara+F%3BKoch%2C+Dan+C%3BSchwindt%2C+Adam+R%3BSchreck%2C+Carl+B%3BAckerman%2C+Luke+K&rft.aulast=Landers&rft.aufirst=Dixon&rft.date=2008-01-01&rft.volume=42&rft.issue=7&rft.spage=2334&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes702348j LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Recreation; Pollution detection; Anadromous species; Dieldrin; DDT; Pesticides; Aromatic hydrocarbons; Pollution effects; Brominated hydrocarbons; Freshwater fish; PCB; Public health; Wildlife; national parks; Cancer; Mountains; Lakes; polybrominated diphenyl ethers; Insecticides; Recreation areas; guidelines; Oceans; hexachlorocyclohexane; fishing; PCB compounds; Bioaccumulation; Pollutants; Polychlorinated Biphenyls; Water Pollution Effects; Standards; Fish; Salmonidae; USA; Canada; ANE, Europe; INW, Asia; I, Pacific; Freshwater DO - http://dx.doi.org/10.1021/es702348j ER - TY - JOUR T1 - Combining Existing Monitoring Sites with a Probability Survey Design-- Examples from U.S. EPA's National Coastal Assessment AN - 19471371; 8237206 AB - U.S. Environmental Protection Agency's (EPA's) National Coastal Assessment was envisioned as a research effort led by EPA's Office of Research and Development to evaluate assessment methods for ecosystem condition monitoring. The program was conducted through strategic partnerships with the coastal states. These states conducted the survey in their waters with a common set of indicators. The resources targeted for initial monitoring were estuarine waters. A flexible probability survey design was used to incorporate, to the extent possible, existing state monitoring program sites. Three criteria were developed to evaluate existing monitoring program sites in the northeastern United States for possible incorporation into the national design: (1) the sites were selected to be representative, (2) the variables sampled at the sites were similar in distribution with variables from a probability design, and (3) the correlation structure of variables was equivalent to that for a probability design. Detailed examples were presented for Long Island Sound water quality sites, New Jersey coastal water quality sites, and Casco Bay, ME, sediment sites to illustrate the approach. JF - Open Environmental & Biological Monitoring Journal AU - Paul, John F AU - Walker, Henry A AU - Galloway, Walter AU - Pesch, Gerald AU - Cobb, Donald AU - Strobel, Charles J AU - Summers, JKevin AU - Charpentier, Michael AU - Heltshe, James AD - National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Mail Drop B343-06, Research Triangle Park, NC 27711 USA Y1 - 2008///0, PY - 2008 DA - 0, 2008 SP - 16 EP - 25 PB - Bentham Science Publishers B.V., P.O. Box 1673 Hilversum 1200 BR The Netherlands VL - 1 KW - Ecology Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources; Pollution Abstracts KW - Survey data KW - probability samples KW - estuaries KW - water quality KW - Coastal states KW - Water quality KW - Islands KW - Biological monitoring KW - Brackishwater environment KW - Environmental monitoring KW - Sediment pollution KW - ANW, USA, Long Island Sound KW - Environmental assessment KW - Estuaries KW - Brackish KW - Coastal waters KW - Sediments KW - Environmental protection KW - EPA KW - Coastal zone KW - ANW, USA, New Jersey KW - ANW, USA, Maine, Casco Bay KW - Environmental conditions KW - Casco KW - Research programs KW - Q5 08503:Characteristics, behavior and fate KW - P 2000:FRESHWATER POLLUTION KW - Q2 09184:Composition of water KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19471371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Open+Environmental+%26+Biological+Monitoring+Journal&rft.atitle=Combining+Existing+Monitoring+Sites+with+a+Probability+Survey+Design--+Examples+from+U.S.+EPA%27s+National+Coastal+Assessment&rft.au=Paul%2C+John+F%3BWalker%2C+Henry+A%3BGalloway%2C+Walter%3BPesch%2C+Gerald%3BCobb%2C+Donald%3BStrobel%2C+Charles+J%3BSummers%2C+JKevin%3BCharpentier%2C+Michael%3BHeltshe%2C+James&rft.aulast=Paul&rft.aufirst=John&rft.date=2008-01-01&rft.volume=1&rft.issue=&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=Open+Environmental+%26+Biological+Monitoring+Journal&rft.issn=1875-0400&rft_id=info:doi/10.2174%2F1875040000801010016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Coastal zone; Coastal states; Environmental assessment; Estuaries; Brackishwater environment; Water quality; Environmental conditions; Environmental protection; Islands; Coastal waters; Sediments; Sediment pollution; water quality; EPA; Biological monitoring; Research programs; Casco; ANW, USA, New Jersey; ANW, USA, Long Island Sound; ANW, USA, Maine, Casco Bay; Brackish DO - http://dx.doi.org/10.2174/1875040000801010016 ER - TY - JOUR T1 - U.S. Air Quality Management: Local, Regional and Global Approaches AN - 19467761; 7965160 AB - The purpose of this article is to review approaches to air quality management (AQM) in the United States. To characterize AQM in the United States, four examples that addressed local, regional, and global scale air pollution are described. These examples include: (1) the Hazardous Air Pollutants (HAPs) program, (2) National Ambient Air Quality Standards (NAAQS) program, (3) "Cap & Trade" programs, and (4) U.S. global pollution control efforts. These four examples were chosen because each presents a different approach to AQM. This was not intended to be a comprehensive description of U.S. AQM programs, but rather representative of selected examples that highlight the themes of this program. Some general principles that are illustrated in the article and are considered important characteristics of U.S. AQM are: Ensure open access to information and transparency in decision making. Develop and sustain a well-trained workforce. Facilitate training, networking, and technology transfer among air quality managers. Integrate planning and coordination of efforts across jurisdictions (across federal, state, and local agencies). Educate and encourage participation of stakeholders. Balance of societal benefits and costs. Apply innovative approaches, where possible. Fund research to improve the scientific basis for problem identification and effective AQM strategy development. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Cote, I AU - Samet, J AU - Vandenberg, J J AD - National Center for Environmental Assessment, U.S. Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460, USA, cote.ila@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 63 EP - 73 VL - 71 IS - 1-2 SN - 1528-7394, 1528-7394 KW - Pollution Abstracts; Toxicology Abstracts KW - networking KW - Coordination KW - Training KW - Technology transfer KW - jurisdiction KW - Air quality standards KW - transparency KW - Air pollution KW - Decision making KW - USA KW - funds KW - Pollutants KW - Reviews KW - stakeholders KW - Pollution control KW - X 24500:Reviews, Legislation, Book & Conference Notices KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19467761?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=U.S.+Air+Quality+Management%3A+Local%2C+Regional+and+Global+Approaches&rft.au=Cote%2C+I%3BSamet%2C+J%3BVandenberg%2C+J+J&rft.aulast=Cote&rft.aufirst=I&rft.date=2008-01-01&rft.volume=71&rft.issue=1-2&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390701557917 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Air pollution; Decision making; Coordination; Pollutants; Reviews; Pollution control; transparency; Air quality standards; networking; funds; Training; Technology transfer; jurisdiction; stakeholders; USA DO - http://dx.doi.org/10.1080/15287390701557917 ER - TY - JOUR T1 - Focusing on Children's Inhalation Dosimetry and Health Effects for Risk Assessment: An Introduction AN - 19465888; 8024671 AB - Substantial effort has been invested in improving children's health risk assessment in recent years. However, the body of scientific evidence in support of children's health assessment is constantly advancing, indicating the need for continual updating of risk assessment methods. Children's inhalation dosimetry and child-specific adverse health effects are of particular concern for risk assessment. When focusing on this topic within children's health, key issues for consideration include (1) epidemiological evidence of adverse effects following children's exposure to air pollution, (2) ontogeny of the lungs and effects on dosimetry, (3) estimation and variability of children's inhalation rates, and (4) current risk assessment methodologies for addressing children. In this article, existing and emerging information relating to these key issues are introduced and discussed in an effort to better understand children's inhalation dosimetry and adverse health effects for risk assessment. While much useful evidence is currently available, additional research and methods are warranted for improved children's health risk assessment. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Foos, B AU - Marty, M AU - Schwartz, J AU - Bennett, W AU - Moya, J AU - Jarabek, A M AU - Salmon, A G AD - U.S. EPA Office of Children's Health Protection and Environmental Education, MC 1107A, 1200 Pennsylvania Avenue, NW, Washington, DC 20460, USA, foos.brenda@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 149 EP - 165 VL - 71 IS - 3-4 SN - 1528-7394, 1528-7394 KW - Health & Safety Science Abstracts; Risk Abstracts; Pollution Abstracts; Toxicology Abstracts KW - Risk assessment KW - Inhalation KW - Dosimetry KW - Children KW - Air pollution KW - Lung KW - Ontogeny KW - Side effects KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19465888?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Focusing+on+Children%27s+Inhalation+Dosimetry+and+Health+Effects+for+Risk+Assessment%3A+An+Introduction&rft.au=Foos%2C+B%3BMarty%2C+M%3BSchwartz%2C+J%3BBennett%2C+W%3BMoya%2C+J%3BJarabek%2C+A+M%3BSalmon%2C+A+G&rft.aulast=Foos&rft.aufirst=B&rft.date=2008-01-01&rft.volume=71&rft.issue=3-4&rft.spage=149&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390701597871 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Air pollution; Inhalation; Risk assessment; Lung; Dosimetry; Ontogeny; Children; Side effects DO - http://dx.doi.org/10.1080/15287390701597871 ER - TY - JOUR T1 - Children's Response to Air Pollutants AN - 19459033; 8024677 AB - It is important to focus on children with respect to air pollution because (1) their lungs are not completely developed, (2) they can have greater exposures than adults, and (3) those exposures can deliver higher doses of different composition that may remain in the lung for greater duration. The undeveloped lung is more vulnerable to assault and less able to fully repair itself when injury disrupts morphogenesis. Children spend more time outside, where concentrations of combustion-generated air pollution are generally higher. Children have higher baseline ventilation rates and are more physically active than adults, thus exposing their lungs to more air pollution. Nasal breathing in adults reduces some pollution concentrations, but children are more typically mouth-breathers--suggesting that the composition of the exposure mixture at the alveolar level may be different Finally, higher ventilation rates and mouth-breathing may pull air pollutants deeper into children's lungs, thereby making clearance slower and more difficult Children also have immature immune systems, which plays a significant role in asthma. The observed consequences of early life exposure to adverse levels of air pollutants include diminished lung function and increased susceptibility to acute respiratory illness and asthma. Exposure to diesel exhaust, in particular, is an area of concern for multiple endpoints, and deserves further research. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Bateson, T F AU - Schwartz, J AD - U.S. EPA NCEA, 1200 Pennsylvania Avenue NW, Mailcode 8623D, Washington, DC 20460, USA, bateson.thomas@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 238 EP - 243 VL - 71 IS - 3-4 SN - 1528-7394, 1528-7394 KW - Health & Safety Science Abstracts; Pollution Abstracts; Toxicology Abstracts; Immunology Abstracts KW - immune system KW - Injuries KW - Ventilation KW - Respiration KW - Immune system KW - Morphogenesis KW - Pollution effects KW - Respiratory diseases KW - Pollutants KW - Respiratory function KW - Asthma KW - Children KW - Alveoli KW - Exhausts KW - Air pollution KW - Lung KW - Diesel KW - Diesel engines KW - F 06955:Immunomodulation & Immunopharmacology KW - X 24490:Other KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19459033?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Children%27s+Response+to+Air+Pollutants&rft.au=Bateson%2C+T+F%3BSchwartz%2C+J&rft.aulast=Bateson&rft.aufirst=T&rft.date=2008-01-01&rft.volume=71&rft.issue=3-4&rft.spage=238&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287390701598234 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Ventilation; Injuries; Immune system; Respiration; Morphogenesis; Asthma; Children; Alveoli; Exhausts; Air pollution; Pollutants; Lung; Diesel; immune system; Pollution effects; Respiratory function; Respiratory diseases; Diesel engines DO - http://dx.doi.org/10.1080/15287390701598234 ER - TY - JOUR T1 - Parameterization of N sub(2)O sub(5) reaction probabilities on the surface of particles containing ammonium, sulfate, and nitrate AN - 19384822; 8566690 AB - A parameterization was developed for the heterogeneous reaction probability ( gamma ) of N sub(2)O sub(5) as a function of temperature, relative humidity (RH), particle composition, and phase state, for use in advanced air quality models. The reaction probabilities on aqueous NH sub(4)HSO sub(4), (NH sub(4)) sub(2)SO sub(4), and NH sub(4)NO sub(3) were modeled statistically using data and uncertainty values compiled from seven different laboratory studies. A separate regression model was fit to laboratory data for dry NH sub(4)HSO sub(4) and (NH sub(4)) sub(2)SO sub(4) particles, yielding lower gamma values than the corresponding aqueous parameterizations. The regression equations reproduced 80% of the laboratory data within a factor of two and 63% within a factor of 1.5. A fixed value was selected for gamma on ice- containing particles based on a review of the literature. The combined parameterization was applied under atmospheric conditions representative of the eastern United States using 3-dimensional fields of temperature, RH, sulfate, nitrate, and ammonium. The resulting spatial distributions of gamma were contrasted with three other parameterizations that have been applied in air quality models in the past and with atmospheric observational determinations of gamma . Our equations lay the foundation for future research that will parameterize the suppression of gamma when inorganic ammoniated particles are mixed or coated with organic material. Our analyses draw attention to a major uncertainty in the available laboratory data at high RH and highlight a critical need for future laboratory measurements of gamma at low temperature and high RH to improve model simulations of N sub(2)O sub(5) hydrolysis during wintertime conditions. JF - Atmospheric Chemistry and Physics AU - Davis, J M AU - Bhave, P V AU - Foley, K M AD - Atmospheric Modeling Division, US Environmental Protection Agency, Research Triangle Park, NC, USA Y1 - 2008 PY - 2008 DA - 2008 SP - 5295 EP - 5311 PB - European Geophysical Society, Max-Planck-Str. 13 37191 Katlenburg-Lindau Germany, [mailto:egs@copernicus.org], [URL:http://www.copernicus.org/] VL - 8 IS - 16 SN - 1680-7316, 1680-7316 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Relative humidity KW - Sulfates KW - Spatial distribution KW - Statistical analysis KW - Air quality KW - Particulates KW - Low temperatures KW - spatial distribution KW - foundations KW - Ammonium KW - Chemical composition KW - Nitrates KW - Regression models KW - Temperature KW - Simulation KW - Humidity KW - Hydrolysis KW - Air quality models KW - USA KW - Numerical simulations KW - Reviews KW - Atmospheric chemistry KW - low temperature KW - Particle composition KW - M2 551.510.42:Air Pollution (551.510.42) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19384822?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Chemistry+and+Physics&rft.atitle=Parameterization+of+N+sub%282%29O+sub%285%29+reaction+probabilities+on+the+surface+of+particles+containing+ammonium%2C+sulfate%2C+and+nitrate&rft.au=Davis%2C+J+M%3BBhave%2C+P+V%3BFoley%2C+K+M&rft.aulast=Davis&rft.aufirst=J&rft.date=2008-01-01&rft.volume=8&rft.issue=16&rft.spage=5295&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Chemistry+and+Physics&rft.issn=16807316&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA; Particulates; Air quality; Nitrates; Sulfates; Temperature; Ammonium; foundations; Humidity; low temperature; Simulation; spatial distribution; Hydrolysis; Reviews; Atmospheric chemistry; Chemical composition; Air quality models; Statistical analysis; Spatial distribution; Relative humidity; Numerical simulations; Low temperatures; Regression models; Particle composition ER - TY - JOUR T1 - Environmental impact assessment taxonomy providing comprehensive coverage of midpoints, endpoints, damages, and areas of protection AN - 19384280; 8567861 AB - Before conducting a comprehensive impact assessment, such as a life cycle impact assessment (LCIA), there is a need to discuss the range of impacts which could and should be included. Up to this point of time, there has not been a comprehensive list of impacts for potential inclusion available. This research builds upon previous work which surveyed a large component of the comprehensive impact assessment field for cataloging and analysis in greater detail and then expanded it to include those midpoints, endpoints, and damages which could be covered in a more comprehensive impact assessment. In this paper, a seminal effort in the form of a meta-model is presented to facilitate an expanded discussion of the taxonomy of this field. Upon using existing models it was apparent the taxonomy needed to be structured to represent midpoint, endpoint, damage, and weighted levels as they relate to areas of protection for the impact assessment phase. Contrary to recent use in the LCIA field, a distinction will be made between an endpoint measure (which is more of a "count" of impacts) and a damage measure (which is a value-weighted aggregation of two or more endpoints). The authors present a representation of all four levels of impact assessment: midpoint, endpoint, damage, and weighted. This taxonomy was developed to include the existing impacts found in LCIA literature, and then expanded to be more comprehensive and include a larger set of impacts than are normally included within LCIA. The authors recognize this is the first of many steps necessary to capture all potential impacts that should be considered when conducting a comprehensive environmental assessment. The intent is to propose a taxonomy that would greatly facilitate the accumulation and communication of empirical and theoretical knowledge gained by offering a standard vocabulary and structure. JF - Journal of Cleaner Production AU - Bare, Jane C AU - Gloria, Thomas P AD - U.S. Environmental Protection Agency, National Risk Management Research Laboratory, Cincinnati, OH 45268, USA, bare.jane@epa.gov Y1 - 2008 PY - 2008 DA - 2008 SP - 1021 EP - 1035 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 16 IS - 10 SN - 0959-6526, 0959-6526 KW - Sustainability Science Abstracts KW - environmental impact assessment KW - Communications KW - life cycle KW - environmental assessment KW - taxonomy KW - Volatile organic compounds KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19384280?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Cleaner+Production&rft.atitle=Environmental+impact+assessment+taxonomy+providing+comprehensive+coverage+of+midpoints%2C+endpoints%2C+damages%2C+and+areas+of+protection&rft.au=Bare%2C+Jane+C%3BGloria%2C+Thomas+P&rft.aulast=Yang&rft.aufirst=Jun&rft.date=2002-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Null&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Communications; environmental impact assessment; life cycle; environmental assessment; taxonomy; Volatile organic compounds DO - http://dx.doi.org/10.1016/j.jclepro.2007.06.001 ER - TY - JOUR T1 - Assessing the public health significance of subsurface-contaminant vapors intruding into indoor air AN - 1400620970; 2013-056407 AB - To assess the public health significance of exposures via the vapor intrusion pathway for exposure a risk assessment was conducted for a common VOC trichloroethylene (TCE) in an unbiased sample of all the contaminated sites within a large geographic setting (northern New Jersey). Probabilistic methods were used to minimize the impact of single point-estimate input values and to help assess the impact of variability and uncertainty in input parameters. Central-tendency probabilistic methods were used to provide an estimate of the most likely exposure point concentrations. The exposure assessment involved 709 TCE-contaminated groundwater sites with 29,856 groundwater samples from 11,210 monitor wells in the state's Hazsite database. The groundwater mapping component focused on the 78 sites with one or more TCE-contaminated wells located on land classified as residential. The extent of groundwater contamination beyond the monitor well locations was estimated (mapped) using generic GIS-based Inverse Distance Weighted methods on a natural-log scale and additional hypothetical 'clean wells'. The risk assessment focused on the 38 sites with one or more hypothetical residences overlying groundwater with a house-plot averaged concentration greater than 2.7 ug/L. The attenuation of vapors generated from the upper-most groundwater was estimated for the 883 hypothetical overlying residential structures using the USEPA's national empirical database of vapor attenuation factors. Receptor characteristics based on county-level statistics are used to estimate adult individual and childhood age-specific exposures using probabilistic "age at move in" techniques and with possible in-utero and lactation exposures. The exposure estimates are combined with central-tendency probabilistic estimates of toxicity (primarily based on NYDOH, 2006a) to estimate central-tendency risks for the cancer and non-cancer outcomes under study (Non-Hodgkin's Lymphoma and Central Nervous System effects). In general the risks are low and highly skewed. Only those few individuals at the highest level of exposure are estimated to be subject to risks of typical concern. However, the methods used include limitations and these results are not likely to be representative of some other areas of the country. Sensitivity and two-dimensional analyses indicate the inputs for vapor attenuation and groundwater concentration dominate the risk estimates. JF - Proceedings - Annual International Conference on Soils, Sediments, Water and Energy AU - Schuver, Henry J Y1 - 2008 PY - 2008 DA - 2008 SP - 416 EP - 450 PB - University of Massachusetts, Amherst, MA VL - 13 KW - United States KW - chlorinated hydrocarbons KW - concentration KW - pollutants KW - statistical analysis KW - pollution KW - observation wells KW - ground water KW - air pollution KW - carcinogens KW - organic compounds KW - toxicity KW - natural attenuation KW - halogenated hydrocarbons KW - probability KW - trichloroethylene KW - New Jersey KW - uncertainty KW - public health KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1400620970?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+-+Annual+International+Conference+on+Soils%2C+Sediments%2C+Water+and+Energy&rft.atitle=Assessing+the+public+health+significance+of+subsurface-contaminant+vapors+intruding+into+indoor+air&rft.au=Schuver%2C+Henry+J&rft.aulast=Schuver&rft.aufirst=Henry&rft.date=2008-01-01&rft.volume=13&rft.issue=&rft.spage=416&rft.isbn=9780978764021&rft.btitle=&rft.title=Proceedings+-+Annual+International+Conference+on+Soils%2C+Sediments%2C+Water+and+Energy&rft.issn=&rft_id=info:doi/ L2 - http://scholarworks.umass.edu/soilsproceedings/vol13/iss1/ http://scholarworks.umass.edu/soilsproceedings/ LA - English DB - GeoRef N1 - Conference title - 23rd annual international conference on Soil, sediments and water N1 - Copyright - GeoRef, Copyright 2016, American Geosciences Institute. N1 - Date revised - 2013-01-01 N1 - Number of references - 83 N1 - PubXState - MA N1 - Document feature - illus. incl. 5 tables N1 - SuppNotes - Includes appendices N1 - Last updated - 2016-10-25 N1 - CODEN - #07501 N1 - SubjectsTermNotLitGenreText - air pollution; carcinogens; chlorinated hydrocarbons; concentration; ground water; halogenated hydrocarbons; natural attenuation; New Jersey; observation wells; organic compounds; pollutants; pollution; probability; public health; statistical analysis; toxicity; trichloroethylene; uncertainty; United States ER - TY - JOUR T1 - Fisherville Mill; a case study; cost effective remediation through collaboration AN - 1400620914; 2013-056387 AB - The Fisherville Mill site is located on the Blackstone River in Grafton, MA. Soil and groundwater are contaminated with chlorinated VOCs and petroleum. The mill and a groundwater recovery system designed to prevent VOCs from migrating to a public water supply well (Well #3) located approximately 1000 feet southwest of the site were destroyed by fire in August 1999. In November 2000, TCE was detected in Well #3. After notification, site investigation efforts focused on evaluating potential migration pathways to Well #3. Based on site investigation results, the USEPA installed a temporary dam to alter groundwater flow directions and reduce risk to Well #3. In Situ Chemical Oxidation (ISCO) using sodium permanganate was selected to decrease TCE concentrations in the source area and provide long-term protection for Well #3. Fisherville Redevelopment Company (FRC) took ownership of the site in 2004. A collaborative approach and strategy was developed between FRC, MassDEP and the Town of Grafton that would encourage significant remedial actions while environmental assessment and engineering activities were ongoing. Work completed includes installation of a #6 oil interception and collection infrastructure, and encapsulation of asbestos impacted debris and lead contaminated soil in flowable fill. JF - Proceedings - Annual International Conference on Soils, Sediments, Water and Energy AU - Ollila, Paul AU - Soukup, Jim AU - Brammer, Dean AU - Nowack, Bette AU - Bernat, Eugene AU - Hultstrom, Eric AU - Tsang, Janis Y1 - 2008 PY - 2008 DA - 2008 SP - 108 EP - 151 PB - University of Massachusetts, Amherst, MA VL - 13 KW - United States KW - chlorinated hydrocarbons KW - aquifer vulnerability KW - water quality KW - contaminant plumes KW - observation wells KW - chemical waste KW - Blackstone River KW - environmental analysis KW - remediation KW - ground water KW - Fisherville Mill Site KW - pump tests KW - permanganate KW - Massachusetts KW - halogenated hydrocarbons KW - pollution KW - optimization KW - cost KW - aquifers KW - volatiles KW - organic compounds KW - volatile organic compounds KW - Grafton Massachusetts KW - trichloroethylene KW - water resources KW - brownfields KW - Worcester County Massachusetts KW - permeability KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1400620914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+-+Annual+International+Conference+on+Soils%2C+Sediments%2C+Water+and+Energy&rft.atitle=Fisherville+Mill%3B+a+case+study%3B+cost+effective+remediation+through+collaboration&rft.au=Ollila%2C+Paul%3BSoukup%2C+Jim%3BBrammer%2C+Dean%3BNowack%2C+Bette%3BBernat%2C+Eugene%3BHultstrom%2C+Eric%3BTsang%2C+Janis&rft.aulast=Ollila&rft.aufirst=Paul&rft.date=2008-01-01&rft.volume=13&rft.issue=&rft.spage=108&rft.isbn=9780978764021&rft.btitle=&rft.title=Proceedings+-+Annual+International+Conference+on+Soils%2C+Sediments%2C+Water+and+Energy&rft.issn=&rft_id=info:doi/ L2 - http://scholarworks.umass.edu/soilsproceedings/vol13/iss1/ http://scholarworks.umass.edu/soilsproceedings/ LA - English DB - GeoRef N1 - Conference title - 23rd annual international conference on Soil, sediments and water N1 - Copyright - GeoRef, Copyright 2016, American Geosciences Institute. N1 - Date revised - 2013-01-01 N1 - Number of references - 12 N1 - PubXState - MA N1 - Document feature - illus. incl. sketch map N1 - Last updated - 2016-10-25 N1 - CODEN - #07501 N1 - SubjectsTermNotLitGenreText - aquifer vulnerability; aquifers; Blackstone River; brownfields; chemical waste; chlorinated hydrocarbons; contaminant plumes; cost; environmental analysis; Fisherville Mill Site; Grafton Massachusetts; ground water; halogenated hydrocarbons; Massachusetts; observation wells; optimization; organic compounds; permanganate; permeability; pollution; pump tests; remediation; trichloroethylene; United States; volatile organic compounds; volatiles; water quality; water resources; Worcester County Massachusetts ER - TY - JOUR T1 - A simple method for the extraction and quantification of photopigments from Symbiodinium spp. AN - 20812090; 8182488 AB - We have developed a simple, mild extraction procedure using methanol which, when coupled with HPLC analysis and diode array detection (DAD), can be used to quantify the major photopigments found in cultured Symbiodinium spp. Extracts were prepared by suspending, fresh or frozen (-70 super(o)C), wet cell pellets in methanol and sonicating or not sonicating the cell suspensions before soaking the cells for 2 h in an ice bath. To assist the soaking process, cell suspensions were vortex mixed at 30 min intervals. After soaking, 0.5 M ammonium acetate buffer was added (1 part buffer to 9 parts methanol) before suspensions were stored over night at -20 super(o)C. Greater than 92% the recoverable pigment was obtained in the initial extraction of the four major photopigments, chlorophyll c, peridinin, diadinoxanthin, and chlorophyll a. Neither sonication nor freezing substantially increased the recovery of photopigments extracted with methanol. Extraction by other commonly used solvents such as acetone or acetone:water with or without freezing and sonication were less effective. JF - Journal of Experimental Marine Biology and Ecology AU - Rogers, JE AU - Marcovich, D AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Gulf Ecology Division, 1 Sabine Island Dr., Gulf Breeze, FL 32561, United States, Rogers.johne@epa.gov Y1 - 2007/12/28/ PY - 2007 DA - 2007 Dec 28 SP - 191 EP - 197 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 353 IS - 2 SN - 0022-0981, 0022-0981 KW - Ecology Abstracts; ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Cell suspensions KW - High-performance liquid chromatography KW - Molecular structure KW - Marine KW - Ice KW - Symbiodinium KW - Chlorophyll KW - Suspension KW - photopigments KW - Methanol KW - Freezing KW - Solvents KW - Phytoplankton KW - Ammonium acetate KW - Primary production KW - Sonication KW - Methodology KW - Acetone KW - Ammonium compounds KW - O 1070:Ecology/Community Studies KW - K 03300:Methods KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08481:Productivity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20812090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.atitle=A+simple+method+for+the+extraction+and+quantification+of+photopigments+from+Symbiodinium+spp.&rft.au=Rogers%2C+JE%3BMarcovich%2C+D&rft.aulast=Rogers&rft.aufirst=JE&rft.date=2007-12-28&rft.volume=353&rft.issue=2&rft.spage=191&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.issn=00220981&rft_id=info:doi/10.1016%2Fj.jembe.2007.08.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Molecular structure; Suspension; Phytoplankton; Primary production; Methodology; Ammonium compounds; High-performance liquid chromatography; Cell suspensions; Ice; Chlorophyll; photopigments; Methanol; Solvents; Freezing; Acetone; Ammonium acetate; Sonication; Symbiodinium; Marine DO - http://dx.doi.org/10.1016/j.jembe.2007.08.022 ER - TY - JOUR T1 - Enantioselective microbial transformation of the phenylpyrazole insecticide fipronil in anoxic sediments. AN - 70073120; 18200855 AB - Fipronil, a chiral insecticide, was biotransformed initially to fipronil sulfide in anoxic sediment slurries following a short lag period. Sulfidogenic or methanogenic sediments transformed fipronil with half-lives of approximately 35 and 40 days, respectively. In all microbially active sediment slurries tested, the transformation of fipronil to fipronil sulfide was enantioselective. In the sulfidogenic sediment slurry, the enantiomeric fraction (EF) of fipronil decreased from an initial racemic EF value of 0.46 to a value of 0.22 during the incubation period of active fipronil transformation, indicating preferential transformation of the S-(+)-enantiomer. A previously unidentified product, 5-amino1-[2,6-dichloro-4-(trifluoromethyl)-phenyl]-4-(trifluoromethylthio)-1-H-pyrazole-3-carboxyamide, or fipronil sulfide-amide, was detected in the sulfidogenic slurries and coincided with the loss of fipronil sulfide. Biota from methanogenic freshwater sediment slurries also transformed fipronil enantioselectively but with a preference for the R-(-)-enantiomer. In all microbially inhibited (autoclaved) sediment slurries tested, no changes in the enantiomeric fractions of fipronil were observed and only low levels (< 5% of the added fipronil) of the fipronil sulfide metabolite were detected. In defined (model) chemical experiments, solutions of pyrite (FeS2) and iron sulfide (FeS) non-enantioselectively transformed fipronil primarily to either 2,6-dichloro-4-(trifluoromethyl)-aniline or to fipronil sulfide and fipronil amide, respectively. This report provides the first experimental evidence of enantioselective microbial transformation of fipronil in a natural environment (soil, water, and sediment) as well as identification of a novel fipronil biotransformation product. JF - Environmental science & technology AU - Jones, W Jack AU - Mazur, Christopher S AU - Kenneke, John F AU - Garrison, A Wayne AD - Ecosystems Research Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, 960 College Station Rd., Athens, Georgia 30605, USA. jones.jack@epa.gov Y1 - 2007/12/15/ PY - 2007 DA - 2007 Dec 15 SP - 8301 EP - 8307 VL - 41 IS - 24 SN - 0013-936X, 0013-936X KW - Insecticides KW - 0 KW - Pyrazoles KW - fipronil KW - QGH063955F KW - Oxygen KW - S88TT14065 KW - Index Medicus KW - Mass Spectrometry KW - Stereoisomerism KW - Chromatography, Gas KW - Biotransformation KW - Pyrazoles -- metabolism KW - Insecticides -- metabolism KW - Oxygen -- chemistry KW - Geologic Sediments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70073120?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Enantioselective+microbial+transformation+of+the+phenylpyrazole+insecticide+fipronil+in+anoxic+sediments.&rft.au=Jones%2C+W+Jack%3BMazur%2C+Christopher+S%3BKenneke%2C+John+F%3BGarrison%2C+A+Wayne&rft.aulast=Jones&rft.aufirst=W&rft.date=2007-12-15&rft.volume=41&rft.issue=24&rft.spage=8301&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-12 N1 - Date created - 2008-01-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Repeating history: pharmaceuticals in the environment. AN - 70065468; 18200843 JF - Environmental science & technology AU - Ankley, Gerald T AU - Brooks, Bryan W AU - Huggett, Duane B AU - Sumpter, John P AD - U.S. EPA, USA. ankley.gerald@epa.gov Y1 - 2007/12/15/ PY - 2007 DA - 2007 Dec 15 SP - 8211 EP - 8217 VL - 41 IS - 24 SN - 0013-936X, 0013-936X KW - Biomarkers KW - 0 KW - Environmental Pollutants KW - Pharmaceutical Preparations KW - Index Medicus KW - Ecosystem KW - Drug Industry KW - Animals KW - Risk Assessment KW - Environmental Pollutants -- toxicity KW - Environmental Pollutants -- analysis KW - Pharmaceutical Preparations -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70065468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Repeating+history%3A+pharmaceuticals+in+the+environment.&rft.au=Ankley%2C+Gerald+T%3BBrooks%2C+Bryan+W%3BHuggett%2C+Duane+B%3BSumpter%2C+John+P&rft.aulast=Ankley&rft.aufirst=Gerald&rft.date=2007-12-15&rft.volume=41&rft.issue=24&rft.spage=8211&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-12 N1 - Date created - 2008-01-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Identification of estrogenic compounds emitted from the combustion of computer printed circuit boards in electronic waste. AN - 70064377; 18200886 AB - Rapid changes in technology have brought about a surge in demand for electronic equipment. Many of these products contain brominated flame-retardants (BFRs) as additives to decrease the rate of combustion, raising concerns about their toxicological risk. In our study, emissions from the combustion of computer-printed circuit boards were evaluated in the T47D-KBluc estrogen-responsive cell line at a series of concentrations. There was significant activity from the emission extract when compared to the positive control, 0.1 nM estradiol. After HPLC fractionation, GC/MS identified ten chemicals which included bisphenol A; the brominated derivates mono-, di-, and tribisphenol, triphenyl phosphate, triphenyl phosphine oxide, 4'-bromo-[1,1'-biphenyl]-4-ol,3,5-dibromo-4-hydroxybiphenyl,3,5-dibromo-2-hydroxybiphenyl, and the oxygenated polyaromatic hydrocarbon benzanthrone. Commercially available samples of these ten compounds were tested. The compound 4'-bromo-[1,1'-biphenyl]-4-ol resulted in dose-dependent significant increases for luciferase activity at concentrations ranging from 0.1 to 10 microM in the T47D-KBluc assay. The chemical also demonstrated an affinity for binding to the estrogen receptor (ER) with an IC50 of 2 x 10(-7) M. To determine the uterotrophic activity, three doses (50, 100, and 200 mg/kg/day) of 4'-bromo-[1,1'-biphenyl]-4-ol were administered to adult ovariectomized Long-Evans rats for 3 days. Treatment of the animals with 200 mg/ kg/day showed an increase in uterine weight Hence one new chemical, released by burning of electrical wastes, was identified which displays estrogenic activity both in vitro and in vivo. However, it was about 1000-fold less potent than ethynyl estradiol. JF - Environmental science & technology AU - Owens, Clyde V AU - Lambright, Christy AU - Bobseine, Kathy AU - Ryan, Bryce AU - Gray, L Earl AU - Gullett, Brian K AU - Wilson, Vickie S AD - National Risk Management Research LaboratoryReproductive Toxicology Division, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. owens.clyde@epa.gov Y1 - 2007/12/15/ PY - 2007 DA - 2007 Dec 15 SP - 8506 EP - 8511 VL - 41 IS - 24 SN - 0013-936X, 0013-936X KW - Estrogens KW - 0 KW - Receptors, Estrogen KW - Index Medicus KW - Rats KW - Animals KW - Rats, Long-Evans KW - Gas Chromatography-Mass Spectrometry KW - Receptors, Estrogen -- metabolism KW - Uterus -- drug effects KW - Female KW - Chromatography, High Pressure Liquid KW - Hot Temperature KW - Estrogens -- pharmacology KW - Estrogens -- metabolism KW - Computers KW - Refuse Disposal KW - Estrogens -- analysis KW - Electronics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70064377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Identification+of+estrogenic+compounds+emitted+from+the+combustion+of+computer+printed+circuit+boards+in+electronic+waste.&rft.au=Owens%2C+Clyde+V%3BLambright%2C+Christy%3BBobseine%2C+Kathy%3BRyan%2C+Bryce%3BGray%2C+L+Earl%3BGullett%2C+Brian+K%3BWilson%2C+Vickie+S&rft.aulast=Owens&rft.aufirst=Clyde&rft.date=2007-12-15&rft.volume=41&rft.issue=24&rft.spage=8506&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-12 N1 - Date created - 2008-01-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Types and quantities of leftover drugs entering the environment via disposal to sewage - Revealed by coroner records AN - 20698167; 8285884 AB - Pharmaceuticals designed for humans and animals often remain unused for a variety of reasons, ranging from expiration to a patient's non-compliance. These leftover, accumulated drugs represent sub-optimal delivery of health care and the potential for environmentally unsound disposal, which can pose exposure risks for humans and wildlife. A major unknown with respect to drugs as pollutants is what fractions of drug residues occurring in the ambient environment result from discarding leftover drugs. To gauge the significance of leftover drugs as potential pollutants, data are needed on the types, quantities, and frequencies with which drugs accumulate. Absence of this data has prevented assessments of the significance of drug accumulation and disposal as a contributing source of drug residues in the environment. One particular source of drug accumulation is those drugs that become ''orphaned'' by the death of a consumer. A new approach to acquiring the data needed to assess the magnitude and extent of drug disposal as a source of environmental pollution is presented by using the inventories of drugs maintained by coroner offices. The data from one metropolitan coroner's office demonstrates proof of concept. Coroner data on leftover drugs are useful for measuring the types and amounts of drugs accumulated by consumers. This inventory also provides an accurate measure of the individual active ingredients actually disposed into sewage by coroners. The types of questions these data can address are presented, and the possible uses of these data for deriving estimates of source contributions from the population at large are discussed. The approach is proposed for nationwide implementation (and automation) to better understand the significance of consumer disposal of medications. JF - Science of the Total Environment AU - Ruhoy, I S AU - Daughton, C G AD - National Exposure Research Laboratory, US Environmental Protection Agency, 944 East Harmon Avenue, Las Vegas, Nevada 89119, United States, daughton.christian@epa.gov Y1 - 2007/12/15/ PY - 2007 DA - 2007 Dec 15 SP - 137 EP - 148 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 388 IS - 1-3 SN - 0048-9697, 0048-9697 KW - Environmental Engineering Abstracts; Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20698167?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Science+of+the+Total+Environment&rft.atitle=Types+and+quantities+of+leftover+drugs+entering+the+environment+via+disposal+to+sewage+-+Revealed+by+coroner+records&rft.au=Ruhoy%2C+I+S%3BDaughton%2C+C+G&rft.aulast=Ruhoy&rft.aufirst=I&rft.date=2007-12-15&rft.volume=388&rft.issue=1-3&rft.spage=137&rft.isbn=&rft.btitle=&rft.title=Science+of+the+Total+Environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2007.08.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2011-12-13 DO - http://dx.doi.org/10.1016/j.scitotenv.2007.08.013 ER - TY - JOUR T1 - Special issue on interpretation of epidemiologic studies of multipollutant ambient air exposure and health effects AN - 877580105; 13653118 JF - Journal of Exposure Science and Environmental Epidemiology AU - Kim, Jee Young AU - Grant, Lester D AU - Burnett, Richard T AD - aU.S. EPA, National Center for Environmental Assessment-RTP Division, Research Triangle Park, North Carolina, USA Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - S1 PB - Nature Publishing Group, The Macmillan Building London N1 9XW UK VL - 17 IS - S2 SN - 1559-0631, 1559-0631 KW - Toxicology Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877580105?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.atitle=Special+issue+on+interpretation+of+epidemiologic+studies+of+multipollutant+ambient+air+exposure+and+health+effects&rft.au=Kim%2C+Jee+Young%3BGrant%2C+Lester+D%3BBurnett%2C+Richard+T&rft.aulast=Kim&rft.aufirst=Jee&rft.date=2007-12-01&rft.volume=17&rft.issue=S2&rft.spage=S1&rft.isbn=&rft.btitle=&rft.title=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.issn=15590631&rft_id=info:doi/10.1038%2Fsj.jes.7500622 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2011-12-14 DO - http://dx.doi.org/10.1038/sj.jes.7500622 ER - TY - JOUR T1 - Influence of exposure error and effect modification by socioeconomic status on the association of acute cardiovascular mortality with particulate matter in Phoenix AN - 877580068; 13653116 AB - Using ZIP code-level mortality data, the association of cardiovascular mortality with PM sub(2.5) and PM sub(10-2.5), measured at a central monitoring site, was determined for three populations at different distances from the monitoring site but with similar numbers of deaths and therefore similar statistical power. The % risk and statistical significance for the association of mortality with PM sub(2.5) fell off with distance from the monitor, as would be expected if exposure error increased with distance. However, the % risk for PM sub(10-2.5) increased in going from the population in Central Phoenix, where the monitoring site was located, to a population in a Middle Ring around Phoenix and fell off in an Outer Ring population. The % risks for the Outer Ring were low for each of the six lag days (0-5) and for the 6-day moving average. The lag structures for PM sub(2.5) and PM sub(10-2.5) also differed for the Central Phoenix and Middle Ring populations. These differences led us to examine the socioeconomic status (SES) of the populations. On the basis of education and income, the population in Central Phoenix had a lower SES than the Middle Ring. Thus, the differences between Central Phoenix and the Middle Ring may be due to effect modification by SES and differences in exposure error. However, the effect modification by SES may be different for thoracic coarse particulate matter (PM) than for fine PM. This study provides new information on the association of PM sub(10-2.5) with cardiovascular mortality. In the Middle Ring, the % risk per 10kg/m super(3) increase in PM sub(10-2.5) concentration (lower and upper 95% confidence levels) for lag day 1 was 3.4 (1.0, 5.8) and for the 6-day distributed-lag was 3.8 (0.3, 7.5). The differences in lag structure for PM sub(2.5) and PM sub(10-2.5) provide evidence that the two particle size classes have health effects that are different and independent. This study also helps explain the high % risks for PM sub(2.5) found for Central Phoenix, 6.6 (1.1, 12.5) for lag day 1, and 11.5 (2.8, 20.9) for the 6-day moving average. The smaller area may have a lower exposure error, and the lower SES population may be more susceptible to fine PM as compared to the larger areas and more heterogeneous populations used in many studies.Journal of Exposure Science and Environmental Epidemiology (2007) 17, S11-S19; doi:10.1038/sj.jes.7500620 JF - Journal of Exposure Science and Environmental Epidemiology AU - Wilson, William E AU - Mar, Therese F AU - Koenig, Jane Q AD - aNational Center for Environmental Assessment, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - S11 EP - S19 PB - Nature Publishing Group, The Macmillan Building London N1 9XW UK VL - 17 IS - S2 SN - 1559-0631, 1559-0631 KW - Toxicology Abstracts; Risk Abstracts KW - Particle size KW - Mortality KW - Statistics KW - Data processing KW - Particulate matter KW - Socioeconomics KW - Particulates KW - Socio-economic aspects KW - Education KW - Epidemiology KW - income KW - Risk factors KW - Thorax KW - Cardiovascular diseases KW - X 24490:Other KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877580068?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.atitle=Influence+of+exposure+error+and+effect+modification+by+socioeconomic+status+on+the+association+of+acute+cardiovascular+mortality+with+particulate+matter+in+Phoenix&rft.au=Wilson%2C+William+E%3BMar%2C+Therese+F%3BKoenig%2C+Jane+Q&rft.aulast=Wilson&rft.aufirst=William&rft.date=2007-12-01&rft.volume=17&rft.issue=S2&rft.spage=S11&rft.isbn=&rft.btitle=&rft.title=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.issn=15590631&rft_id=info:doi/10.1038%2Fsj.jes.7500620 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Particle size; Socio-economic aspects; Mortality; Data processing; Statistics; Epidemiology; Risk factors; Particulate matter; Thorax; Cardiovascular diseases; Education; income; Socioeconomics; Particulates DO - http://dx.doi.org/10.1038/sj.jes.7500620 ER - TY - JOUR T1 - Property changes in aqueous solutions due to surfactant treatment of PCE; implications to geophysical measurements AN - 762680344; 2010-089196 JF - Eos, Transactions, American Geophysical Union AU - Werkema, D D AU - Anonymous Y1 - 2007/12// PY - 2007 DA - December 2007 SP - Abstract NS11B EP - 0499 PB - American Geophysical Union, Washington, DC VL - 88 IS - 52, Suppl. SN - 0096-3941, 0096-3941 KW - chlorinated hydrocarbons KW - concentration KW - experimental studies KW - monitoring KW - oxygen KW - physicochemical properties KW - geophysical methods KW - dye tracers KW - prediction KW - pollution KW - aqueous solutions KW - tetrachloroethylene KW - research KW - remediation KW - ground water KW - aquifers KW - organic compounds KW - dissolved oxygen KW - dissolved materials KW - surfactants KW - halogenated hydrocarbons KW - pH KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762680344?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Eos%2C+Transactions%2C+American+Geophysical+Union&rft.atitle=Property+changes+in+aqueous+solutions+due+to+surfactant+treatment+of+PCE%3B+implications+to+geophysical+measurements&rft.au=Werkema%2C+D+D%3BAnonymous&rft.aulast=THOMAS&rft.aufirst=ROY&rft.date=1976-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=THE+EFFECTS+OF+THREE+METHODS+ON+TEST+ANXIETY+AND+THE+ACHIEVEMENT+TEST+PERFORMANCE+OF+ELEMENTARY+STUDENTS%3A++PROVIDING+TEST-TAKING+INFORMATION%2C+TEST-WISENESS+TRAINING%2C+AND+SYSTEMATIC+DESENSITIZATION.&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - American Geophysical Union 2007 fall meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - PubXState - DC N1 - Last updated - 2012-06-07 N1 - CODEN - EOSTAJ N1 - SubjectsTermNotLitGenreText - aqueous solutions; aquifers; chlorinated hydrocarbons; concentration; dissolved materials; dissolved oxygen; dye tracers; experimental studies; geophysical methods; ground water; halogenated hydrocarbons; monitoring; organic compounds; oxygen; pH; physicochemical properties; pollution; prediction; remediation; research; surfactants; tetrachloroethylene ER - TY - JOUR T1 - Lead hepatotoxicity & potential health effects. AN - 70065528; 18219078 AB - Occupational and environmental exposures to lead (Pb), one of the toxic metal pollutants, is of global concern. Health risks are increasingly associated with environmental exposures to Pb emissions from, for example, the widespread use of leaded gasoline in developing countries. Exposure occurs mainly through the respiratory and gastrointestinal systems, and the ingested and absorbed Pb is stored primarily in soft tissues and bone. Autopsy studies of Pb-exposed patients have shown a large amount (approximately 33%) of the absorbed Pb in soft tissue stored in liver. In addition to neuronal encephalopathy observed in persons after exposure to very high concentrations of Pb, gastrointestinal colic (abdominal pain, constipation, intestinal paralysis) is a consistent early symptom of Pb poisoning in humans. Such severe gastrointestinal effects are consistently observed in patients with a blood Pb range of 30 to 80 microg/dl. Ingestion of Pb is one of the primary causes of its hepatotoxic effects. Hepatocarcinogenic effects of Pb reported in animal toxicology studies have led to new research into the biochemical and molecular aspects of Pb toxicology. Gains in the molecular understanding of Pb effects on hepatic drug metabolizing enzymes, cholesterol metabolism, oxidative stress, and hepatic hyperplasia suggest a potential role for Pb in damaging extrahepatic systems, including the cardiovascular system. This review also discusses the therapeutic potential of chelation therapy in treating Pb-induced hepatotoxicity in animals. JF - The Indian journal of medical research AU - Mudipalli, Anuradha AD - National Center for Environmental Assessment, Office of Research & Development, U.S. EPA, North Carolina 27709, USA. Mudipalli.anu@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 518 EP - 527 VL - 126 IS - 6 SN - 0971-5916, 0971-5916 KW - Chelating Agents KW - 0 KW - Lead KW - 2P299V784P KW - Heme KW - 42VZT0U6YR KW - Cytochrome P-450 Enzyme System KW - 9035-51-2 KW - Cholesterol KW - 97C5T2UQ7J KW - Index Medicus KW - Occupational Exposure KW - Animals KW - Hyperplasia KW - Chelating Agents -- therapeutic use KW - Cholesterol -- metabolism KW - Humans KW - Oxidative Stress -- drug effects KW - Environmental Exposure KW - Disease Models, Animal KW - Cytochrome P-450 Enzyme System -- metabolism KW - Heme -- metabolism KW - Lead Poisoning -- therapy KW - Liver -- pathology KW - Liver -- injuries KW - Liver -- drug effects KW - Lead Poisoning -- pathology KW - Lead -- toxicity KW - Liver -- metabolism KW - Lead Poisoning -- etiology KW - Lead Poisoning -- metabolism KW - Lead -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70065528?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apqdtglobal&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=ProQuest+Dissertations+and+Theses&rft.atitle=RELATION+OF+TEST-TAKING+STRATEGY+AND+SELECTED+FACTORS+TO+OUTCOME+ON+OBJECTIVE+TESTS&rft.au=LANGER%2C+GARY+RICHARD&rft.aulast=LANGER&rft.aufirst=GARY&rft.date=1980-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=ProQuest+Dissertations+and+Theses&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-05-02 N1 - Date created - 2008-01-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Impact of underestimating the effects of cold temperature on motor vehicle start emissions of air toxics in the United States. AN - 70058503; 18200932 AB - Analyses of U.S. Environmental Protection Agency (EPA) certification data, California Air Resources Board surveillance testing data, and EPA research testing data indicated that EPA's MOBILE6.2 emission factor model substantially underestimates emissions of gaseous air toxics occurring during vehicle starts at cold temperatures for light-duty vehicles and trucks meeting EPA Tier 1 and later standards. An unofficial version of the MOBILE6.2 model was created to account for these underestimates. When this unofficial version of the model was used to project emissions into the future, emissions increased by almost 100% by calendar year 2030, and estimated modeled ambient air toxics concentrations increased by 6-84%, depending on the pollutant. To address these elevated emissions, EPA recently finalized standards requiring reductions of emissions when engines start at cold temperatures. JF - Journal of the Air & Waste Management Association (1995) AU - Cook, Richard AU - Touma, Jawad S AU - Fernandez, Antonio AU - Brzezinski, David AU - Bailey, Chad AU - Scarbro, Carl AU - Thurman, James AU - Strum, Madeleine AU - Ensley, Darrell AU - Baldauf, Richard AD - U.S. Environmental Protection Agency, Office of Transportation and Air Quality, National Vehicle and Fuel Emissions Laboratory, Ann Arbor, MI 48103, USA. cook.rich@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 1469 EP - 1479 VL - 57 IS - 12 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Gasoline KW - Vehicle Emissions KW - Index Medicus KW - United States KW - Environmental Monitoring KW - Air Pollution -- analysis KW - Cold Temperature KW - Air Pollutants -- analysis KW - Motor Vehicles KW - Air Pollutants -- chemistry KW - Vehicle Emissions -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70058503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Impact+of+underestimating+the+effects+of+cold+temperature+on+motor+vehicle+start+emissions+of+air+toxics+in+the+United+States.&rft.au=Cook%2C+Richard%3BTouma%2C+Jawad+S%3BFernandez%2C+Antonio%3BBrzezinski%2C+David%3BBailey%2C+Chad%3BScarbro%2C+Carl%3BThurman%2C+James%3BStrum%2C+Madeleine%3BEnsley%2C+Darrell%3BBaldauf%2C+Richard&rft.aulast=Cook&rft.aufirst=Richard&rft.date=2007-12-01&rft.volume=57&rft.issue=12&rft.spage=1469&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-25 N1 - Date created - 2008-01-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Pollution prevention and community environmental health: opening doors through cooperation and partnerships. AN - 70055231; 18189040 JF - Journal of environmental health AU - Lewis, Harry AD - Community Action for a Renewed Environment Program, Office of Pollution Prevention and Toxics Pollution Prevention Division, U.S. Environmental Protection Agency, Washington, DC 20460, USA. lewis.harry@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 45 EP - 46 VL - 70 IS - 5 SN - 0022-0892, 0022-0892 KW - Index Medicus KW - Humans KW - Environmental Pollution -- prevention & control KW - Public Health KW - Environmental Health KW - Conservation of Natural Resources -- methods KW - Community-Institutional Relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70055231?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+health&rft.atitle=Pollution+prevention+and+community+environmental+health%3A+opening+doors+through+cooperation+and+partnerships.&rft.au=Lewis%2C+Harry&rft.aulast=Lewis&rft.aufirst=Harry&rft.date=2007-12-01&rft.volume=70&rft.issue=5&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+health&rft.issn=00220892&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-14 N1 - Date created - 2008-01-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CONF T1 - Panel discussion review: session two--interpretation of observed associations between multiple ambient air pollutants and health effects in epidemiologic analyses. AN - 69061687; 18079769 AB - Air pollution epidemiologic research has often utilized ambient air concentrations measured from centrally located monitors as a surrogate measure of exposure to these pollutants. Associations between these ambient concentrations and health outcomes such as lung function, hospital admissions, and mortality have been examined in short- and long-term cohort studies as well as in time-series and case-crossover studies. The issues related to interpreting the observed associations of ambient air pollutants with health outcomes were discussed at the US EPA sponsored workshop on December 13 and 14, 2006 in Chapel Hill, North Carolina, USA. The second session of this workshop focused on the following topics: (1) statistical methodology and study designs that may improve understanding of multipollutant health effects; (2) ambient concentrations as surrogate measures of pollutant mixtures; and (3) source-focused epidemiologic research. New methodology and approaches to better distinguish the effects of individual pollutants include multicity hierarchical modeling and the use of case-crossover analysis to control for copollutants. An alternative approach is to examine the mixture as a whole using principal component analysis. Another important consideration is to what extent the observed health associations are attributable to individual pollutants, which are often from common sources and are correlated, versus the pollutant mixtures that the pollutants are representing. For example, several ambient air concentrations, such as particulate matter mass, nitrogen dioxide, and carbon monoxide, may be serving as surrogate measures of motor vehicle exhaust. Source apportionment analysis is one method that may allow further advancement in understanding the source components that contribute to multipollutant health effects. JF - Journal of exposure science & environmental epidemiology AU - Kim, Jee Young AU - Burnett, Richard T AU - Neas, Lucas AU - Thurston, George D AU - Schwartz, Joel AU - Tolbert, Paige E AU - Brunekreef, Bert AU - Goldberg, Mark S AU - Romieu, Isabelle Y1 - 2007/12// PY - 2007 DA - December 2007 SP - S83 EP - S89 VL - 17 Suppl 2 KW - Air Pollutants KW - 0 KW - Particulate Matter KW - Index Medicus KW - United States KW - United States Environmental Protection Agency KW - Environmental Health KW - Humans KW - North Carolina KW - Cohort Studies KW - Cross-Over Studies KW - Data Interpretation, Statistical KW - Risk Assessment -- methods KW - Particulate Matter -- toxicity KW - Epidemiologic Studies KW - Environmental Exposure -- analysis KW - Air Pollutants -- analysis KW - Particulate Matter -- analysis KW - Environmental Exposure -- adverse effects KW - Air Pollutants -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69061687?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Journal+of+exposure+science+%26+environmental+epidemiology&rft.atitle=Panel+discussion+review%3A+session+two--interpretation+of+observed+associations+between+multiple+ambient+air+pollutants+and+health+effects+in+epidemiologic+analyses.&rft.au=Kim%2C+Jee+Young%3BBurnett%2C+Richard+T%3BNeas%2C+Lucas%3BThurston%2C+George+D%3BSchwartz%2C+Joel%3BTolbert%2C+Paige+E%3BBrunekreef%2C+Bert%3BGoldberg%2C+Mark+S%3BRomieu%2C+Isabelle&rft.aulast=Kim&rft.aufirst=Jee&rft.date=2007-12-01&rft.volume=17+Suppl+2&rft.issue=&rft.spage=S83&rft.isbn=&rft.btitle=&rft.title=Journal+of+exposure+science+%26+environmental+epidemiology&rft.issn=1559-064X&rft_id=info:doi/10.1038%2Fsj.jes.7500623 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-04-11 N1 - Date created - 2007-12-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1038/sj.jes.7500623 ER - TY - JOUR T1 - Understanding water quality trading: the basics. AN - 69007028; 18049767 AB - The United States has entered a new era in water quality protection: the era of market-based incentives. In January 2003, the United States Environmental Protection Agency (EPA) issued its National Water Quality Trading Policy (Trading Policy) (USEPA, 2003). This action has generated greater interest in water quality trading and has prompted EPA to develop tools and training to assist interested parties in understanding what water quality trading is and what constitutes a successful trading program. JF - Journal of environmental monitoring : JEM AU - Kibler, Virginia M AU - Kasturi, Kavya P AD - Office of Wastewater Management, US Environmental Protection Agency, 1200 Pennsylvania Avenue, NW, MC:4203M, Washington, DC, 20460, USA. kibler.virginia@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 1302 EP - 1305 VL - 9 IS - 12 SN - 1464-0325, 1464-0325 KW - Industrial Waste KW - 0 KW - Index Medicus KW - United States KW - Environment KW - Government Regulation KW - Industry -- legislation & jurisprudence KW - United States Environmental Protection Agency -- legislation & jurisprudence KW - Water Pollution -- legislation & jurisprudence KW - Industrial Waste -- legislation & jurisprudence KW - Water Pollution -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69007028?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+monitoring+%3A+JEM&rft.atitle=Understanding+water+quality+trading%3A+the+basics.&rft.au=Kibler%2C+Virginia+M%3BKasturi%2C+Kavya+P&rft.aulast=Kibler&rft.aufirst=Virginia&rft.date=2007-12-01&rft.volume=9&rft.issue=12&rft.spage=1302&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+monitoring+%3A+JEM&rft.issn=14640325&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-26 N1 - Date created - 2007-11-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Towards quantitative uncertainty assessment for cancer risks: central estimates and probability distributions of risk in dose-response modeling. AN - 68530643; 17905499 AB - Regulatory agencies and the scientific community have been engaged in a long-term effort to strengthen health risk assessment procedures. Recently the momentum of this effort has accelerated to increasing biological information for a variety of toxic compounds and emphasis on the policy goal of broader characterization of scientific uncertainty (in contrast to providing only a single risk estimate). For example, the OMB Regulatory Analysis Guidelines [OMB, 2003. Office of Management and Budget. Circular A-4. Available from: ] suggest that a formal quantitative uncertainty analysis be performed for economic assessments in support of major regulatory analyses, a process that can utilize both expected values and probability distributions for risk estimates. Some efforts have been made in the past to provide probability distributions of risk estimates. In this article, we examine a procedure for constructing probability distributions and expected values of risk estimates using a Bayesian framework. This approach has the advantage of mathematical soundness and computational feasibility, given the Markov chain Monte Carlo software tools that are available today. Importantly, the Bayesian framework can serve as a unifying platform for uncertainty analysis in cancer risk assessment. This paper provides some initial applications of Bayesian methods in quantitative analysis of uncertainty in cancer risk assessment, including implementation with cancer dose-response data sets for two chemicals. The Bayesian expected risk calculations provide an approach to generating a central estimate of risk that does not have the instability problems that have often limited utility of MLE risk estimates. JF - Regulatory toxicology and pharmacology : RTP AU - Kopylev, Leonid AU - Chen, Chao AU - White, Paul AD - National Center of Environmental Assessment, U.S. Environmental Protection Agency, USEPA Office of Research and Development, 1200 Pennsylvania Avenue, NW (8623D), Washington, DC 20460, USA. kopylev.leonid@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 203 EP - 207 VL - 49 IS - 3 SN - 0273-2300, 0273-2300 KW - Index Medicus KW - Animals KW - Dose-Response Relationship, Drug KW - Humans KW - Environmental Exposure -- analysis KW - Algorithms KW - Risk Assessment -- methods KW - Monte Carlo Method KW - Environmental Exposure -- adverse effects KW - Uncertainty KW - Neoplasms -- diagnosis KW - Neoplasms -- chemically induced KW - Bayes Theorem UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68530643?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.atitle=Towards+quantitative+uncertainty+assessment+for+cancer+risks%3A+central+estimates+and+probability+distributions+of+risk+in+dose-response+modeling.&rft.au=Kopylev%2C+Leonid%3BChen%2C+Chao%3BWhite%2C+Paul&rft.aulast=Kopylev&rft.aufirst=Leonid&rft.date=2007-12-01&rft.volume=49&rft.issue=3&rft.spage=203&rft.isbn=&rft.btitle=&rft.title=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.issn=02732300&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-11 N1 - Date created - 2007-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Mercury and stable isotopes of carbon and nitrogen in mink. AN - 68527356; 18020681 AB - Total Hg concentrations and values of stable isotopes (delta(15)N, delta(13)C) in tissues of mink (Mustela vison) captured in Rhode Island (USA) during winters of 1999 to 2004 were statistically distinct based on location. Mink captured in salt marsh environments (salt marsh group mink [SMGM]) had significantly lower mean Hg concentrations in liver and muscle tissue, and significantly higher delta(15)N and delta(13)C values in muscle, than those in corresponding samples of mink from upland freshwater locations (upland group mink [UPGM]). Stomach content samples obtained from the mink carcasses showed that fish, frogs, and crayfish were the dominant food items in UPGM, but in SMGM, fish predominated. Significant correlations were found for total Hg concentrations and stable isotope values between stomach contents and tissues. Comparisons of increases in Hg concentrations and delta(15)N values from stomach contents to muscle tissue showed nonsignificant differences between UPGM and SMGM for Hg concentrations (SMGM, factor of 4.2; UPGM, factor of 3.9) and delta(15)N values (SMGM, difference of 3.9 per thousand; UPGM, difference of 3.1 per thousand). These results suggest that the length of the trophic step and the extent of accumulation of Hg were approximately equal in both mink groups despite the differences in dietary composition and possible differences in accumulation of organic and inorganic Hg. The correspondence of stable isotope values and Hg concentrations between mink tissues and their stomach contents indicates that use of stomach content analysis to identify major prey items, followed by collection and analysis of appropriate field prey, may represent an approach for estimating Hg exposure to mink. JF - Environmental toxicology and chemistry AU - Lake, James L AU - Ryba, Stephan A AU - Serbst, Jonathan AU - Brown, Charles F AU - Gibson, Lori AD - Atlantic Ecology Division-National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Narragansett, Rhode Island 02882, USA. lake.jim@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 2611 EP - 2619 VL - 26 IS - 12 SN - 0730-7268, 0730-7268 KW - Carbon Isotopes KW - 0 KW - Nitrogen Isotopes KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - Stomach -- chemistry KW - Environmental Monitoring KW - Animals KW - Nitrogen Isotopes -- analysis KW - Muscles -- chemistry KW - Reproducibility of Results KW - Mink KW - Carbon Isotopes -- analysis KW - Liver -- chemistry KW - Mercury -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68527356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Mercury+and+stable+isotopes+of+carbon+and+nitrogen+in+mink.&rft.au=Lake%2C+James+L%3BRyba%2C+Stephan+A%3BSerbst%2C+Jonathan%3BBrown%2C+Charles+F%3BGibson%2C+Lori&rft.aulast=Lake&rft.aufirst=James&rft.date=2007-12-01&rft.volume=26&rft.issue=12&rft.spage=2611&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-25 N1 - Date created - 2007-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The complexities of air pollution regulation: the need for an integrated research and regulatory perspective. AN - 68519898; 17609539 AB - The Clean Air Act mandates the U.S. Environmental Protection Agency to periodically reassess existing and new science that underlie the regulation of major ambient pollutants -- particulate matter (PM) and tropospheric ozone being most notable. While toxic effects have been ascribed individually to these and other pollutants in the air, it is clear that mixtures of these contaminants have the potential to interact and thereby influence their overall toxic outcomes. It follows that a more comprehensive assessment of the potential health effects of the air pollution complex might better protect human health; however, traditional regulatory drivers and funding constraints have impeded progress to such a goal. Despite difficulties in empirically conducting studies of complex mixtures of air pollutants and acquiring relevant exposure data, there remains a need to develop integrated, interdisciplinary research and analytical strategies to provide more comprehensive (and relevant) assessments of associated health outcomes and risks. The research and assessment communities are endeavoring to dissect this complexity using varied approaches Here we present five interdisciplinary perspectives of this evolving line of thought among researchers and those who use such data in assessment: (1) analyses that coordinate air quality-health analyses utilizing representative polluted U.S. air sheds to apportion source and component-specific health risks; (2) novel approaches to characterize air quality in terms of emission sources and how emission reduction strategies might effectively impact pollutant levels; (3) insights from present-day studies of effects of single ambient pollutants in animal and controlled clinical toxicology studies and how these are evolving to address air pollution; (4) refinements in epidemiologic health assessments that take advantage of the complexities of existent air quality conditions; and (5) new approaches to integrative analyses to establish the criteria for regulation of PM and other criteria pollutants. As these examples illustrate, implementing multidisciplined and integrative strategies offer the promise of more realistic and relevant science, greater reductions in uncertainty, and improved overall air pollution assessment. The regulatory mandate may lag behind the science, but real gains both in public health benefit and the science to dissect complex problems will result. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Nadadur, Srikanth S AU - Miller, C Andrew AU - Hopke, Philip K AU - Gordon, Terry AU - Vedal, Sverre AU - Vandenberg, John J AU - Costa, Daniel L AD - National Center for Environmental Assessment, US EPA, Research Triangle Park, NC 27711, USA. Nadadurs@niehs.nih.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 318 EP - 327 VL - 100 IS - 2 SN - 1096-6080, 1096-6080 KW - Air Pollutants KW - 0 KW - Particulate Matter KW - Ozone KW - 66H7ZZK23N KW - Index Medicus KW - United States KW - Animals KW - Ozone -- analysis KW - Particle Size KW - Humans KW - Particulate Matter -- adverse effects KW - Particulate Matter -- analysis KW - Ozone -- adverse effects KW - United States Environmental Protection Agency KW - Government Regulation KW - Air Pollution -- adverse effects KW - Air Pollution -- legislation & jurisprudence KW - Biomedical Research -- methods KW - Air Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68519898?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=The+complexities+of+air+pollution+regulation%3A+the+need+for+an+integrated+research+and+regulatory+perspective.&rft.au=Nadadur%2C+Srikanth+S%3BMiller%2C+C+Andrew%3BHopke%2C+Philip+K%3BGordon%2C+Terry%3BVedal%2C+Sverre%3BVandenberg%2C+John+J%3BCosta%2C+Daniel+L&rft.aulast=Nadadur&rft.aufirst=Srikanth&rft.date=2007-12-01&rft.volume=100&rft.issue=2&rft.spage=318&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-20 N1 - Date created - 2007-11-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Tissue distribution and metabolism of benzo[a]pyrene in embryonic and larval medaka (Oryzias latipes). AN - 68518098; 17804863 AB - The need to understand chemical uptake, distribution, and metabolism in embryonic and larval fish derives from the fact that these early life stages often exhibit greater sensitivity to xenobiotic compounds than do adult animals. In this study, a 6-h acute waterborne exposure immediately after fertilization was used to quickly load the egg with benzo[a]pyrene (BaP). This exposure was used to mimic the initial egg concentration of a persistent bioaccumulative toxicant that could result from maternal transfer. We used multiphoton laser scanning microscopy (MPLSM) in combination with conventional analytical chemistry methods to characterize the tissue distribution of BaP and its principal metabolites in medaka embryos and post-hatch larvae. Embryonic metabolism of BaP was evident by MPLSM prior to liver formation or heart development. A major product of this metabolism was identified by liquid chromatography/mass spectrometry as BaP-3-glucuronide. MPLSM showed that metabolites were sequestered within the yolk, biliary system, and gastrointestinal tract. When the gastrointestinal tract became patent a few days after hatch, the metabolites were rapidly eliminated. These findings indicate that some of the earliest embryonic tissues are metabolically competent and that redistribution of BaP and its metabolic products occurs throughout development. Rapid metabolism of BaP substantially reduces the body burden of parent chemical in the developing embryo, potentially reducing toxicity. It remains unclear whether metabolism of BaP in medaka embryos leads to the formation of DNA adducts associated with genotoxic effects or yields metabolites that later lead to other toxicity in juveniles or adults. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Hornung, Michael W AU - Cook, Philip M AU - Fitzsimmons, Patrick N AU - Kuehl, Douglas W AU - Nichols, John W AD - US Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, Duluth, MN 55804, USA. hornung.michael@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 393 EP - 405 VL - 100 IS - 2 SN - 1096-6080, 1096-6080 KW - Carbon Radioisotopes KW - 0 KW - Water Pollutants KW - Benzo(a)pyrene KW - 3417WMA06D KW - Index Medicus KW - Microscopy, Fluorescence KW - Microscopy, Confocal KW - Spectrometry, Mass, Electrospray Ionization KW - Animals KW - Tissue Distribution KW - Chromatography, High Pressure Liquid KW - Embryo, Nonmammalian -- ultrastructure KW - Larva -- metabolism KW - Larva -- ultrastructure KW - Embryo, Nonmammalian -- metabolism KW - Oryzias -- metabolism KW - Benzo(a)pyrene -- pharmacokinetics KW - Embryo, Nonmammalian -- drug effects KW - Oryzias -- embryology KW - Water Pollutants -- pharmacokinetics KW - Larva -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68518098?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Tissue+distribution+and+metabolism+of+benzo%5Ba%5Dpyrene+in+embryonic+and+larval+medaka+%28Oryzias+latipes%29.&rft.au=Hornung%2C+Michael+W%3BCook%2C+Philip+M%3BFitzsimmons%2C+Patrick+N%3BKuehl%2C+Douglas+W%3BNichols%2C+John+W&rft.aulast=Hornung&rft.aufirst=Michael&rft.date=2007-12-01&rft.volume=100&rft.issue=2&rft.spage=393&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-20 N1 - Date created - 2007-11-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Identification of interspecies concordance of mechanisms of arsenic-induced bladder cancer. AN - 68516463; 17720352 AB - Exposure to arsenic causes cancer by inducing a variety of responses that affect the expression of genes associated with numerous biological pathways leading to altered cell growth and proliferation, signaling, apoptosis and oxidative stress response. Affymetrix GeneChip arrays were used to detect gene expression changes following dimethylarsinic acid (DMA) exposure to human bladder cells (UROtsa) or rat bladder cells (MYP3) and rat bladder epithelium in vivo at comparable doses. Using different experimental models coupled with transcriptional profiling allowed investigation of the correlation of mechanisms of DMA-induced toxicity between in vitro and in vivo treatment and across species. Our observations suggest that DMA-induced gene expression in UROtsa cells is distinct from that observed in the MYP3 cells. Principal component analysis shows a more distinct separation by treatment and dose in MYP3 cells as compared to UROtsa cells. However, at the level of pathways and biological networks, DMA affects both common and unique processes in the bladder transitional cells of human and rats. Twelve pathways were found common between human in vitro, rat in vitro and rat in vivo systems. These included signaling pathways involved in adhesion, cellular growth and differentiation. Fifty-five genes found to be commonly expressed between rat in vivo and rat in vitro systems were involved in diverse functions such as cell cycle regulation, lipid metabolism and protein degradation. Many of the genes, processes and pathways have previously been associated with arsenic-induced toxicity. Our finding reiterates and also identifies new biological processes that might provide more information regarding the mechanisms of DMA-induced toxicity. The results of our analysis further suggest that gene expression profiles can address pertinent issues of relevance to risk assessment, namely interspecies extrapolation of mechanistic information as well as comparison of in vitro to in vivo response. JF - Toxicology in vitro : an international journal published in association with BIBRA AU - Sen, Banalata AU - Wolf, Douglas C AU - Turpaz, Yaron AU - Bugrim, Andrej AU - Retief, Jacques AU - Hester, Susan D AD - Environmental Carcinogenesis Division, US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC 27711, USA. sen.banalata@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 1513 EP - 1529 VL - 21 IS - 8 SN - 0887-2333, 0887-2333 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Rats KW - Gene Expression Profiling KW - Animals KW - Rats, Inbred F344 KW - Dose-Response Relationship, Drug KW - Humans KW - Principal Component Analysis KW - Cell Line, Tumor KW - Female KW - Arsenic -- toxicity KW - Urinary Bladder Neoplasms -- metabolism KW - Urinary Bladder Neoplasms -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68516463?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+in+vitro+%3A+an+international+journal+published+in+association+with+BIBRA&rft.atitle=Identification+of+interspecies+concordance+of+mechanisms+of+arsenic-induced+bladder+cancer.&rft.au=Sen%2C+Banalata%3BWolf%2C+Douglas+C%3BTurpaz%2C+Yaron%3BBugrim%2C+Andrej%3BRetief%2C+Jacques%3BHester%2C+Susan+D&rft.aulast=Sen&rft.aufirst=Banalata&rft.date=2007-12-01&rft.volume=21&rft.issue=8&rft.spage=1513&rft.isbn=&rft.btitle=&rft.title=Toxicology+in+vitro+%3A+an+international+journal+published+in+association+with+BIBRA&rft.issn=08872333&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-15 N1 - Date created - 2007-11-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Immunotoxicity: the risk is real. AN - 68513442; 17878151 AB - Several papers published over the last year represent significant progress in closing the gap between rodent immunotoxicity data and human risk and indicate that, at least for the developing immune system, the concern raised by rodent data is justified. The studies reviewed here show that suppression of immune responses in rodents is predictive of suppression of immune responses in humans and that there is a relationship between immune suppression following developmental exposure to the toxicants and enhanced risk of infectious or neoplastic disease in humans. The three cases highlighted here are remarkable in that they all deal with real-world environmental exposures that represent different media -- air (cigarette smoke), water (arsenic), and food (polychlorinated biphenyls [PCBs]) -- and constitute very real risks. Moreover, the arsenic and PCB studies actually demonstrate a quantitative relationship between human exposure and immune suppression. There is evidence that in utero exposure to cigarette smoke and arsenic but not PCBs is associated with increased risk of allergic disease as well. There is clearly potential for designing studies that could address both issues. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Selgrade, Maryjane K AD - US Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, MD B143-01, Research Triangle Park, NC 27711, USA. selgrade.maryjane@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 328 EP - 332 VL - 100 IS - 2 SN - 1096-6080, 1096-6080 KW - Tobacco Smoke Pollution KW - 0 KW - Xenobiotics KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Arsenic -- adverse effects KW - Animals KW - Humans KW - Tobacco Smoke Pollution -- adverse effects KW - Disease Models, Animal KW - Species Specificity KW - Risk Assessment KW - Polychlorinated Biphenyls -- adverse effects KW - Immunosuppression KW - Immune System Diseases -- chemically induced KW - Immune System -- drug effects KW - Immune System -- physiopathology KW - Xenobiotics -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68513442?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Immunotoxicity%3A+the+risk+is+real.&rft.au=Selgrade%2C+Maryjane+K&rft.aulast=Selgrade&rft.aufirst=Maryjane&rft.date=2007-12-01&rft.volume=100&rft.issue=2&rft.spage=328&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-20 N1 - Date created - 2007-11-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Investigation of subsurface flow constructed wetlands and associated geomaterial resources in the Akumal and Reforma regions, Quintana Roo, Mexico AN - 51091514; 2008-032637 JF - Environmental Geology (Berlin) AU - Krekeler, Mark P S AU - Probst, Pete AU - Samsonov, Misha AU - Tselepis, Cynthia M AU - Bates, William AU - Kearns, Lance E AU - Maynard, J Barry Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 709 EP - 726 PB - Springer International, Berlin VL - 53 IS - 4 SN - 0943-0105, 0943-0105 KW - silicates KW - limestone KW - aquifer vulnerability KW - zinc KW - water quality KW - aggregate KW - engineering properties KW - waste water KW - water management KW - lead KW - preferential flow KW - environmental analysis KW - remediation KW - ground water KW - waste management KW - constructed wetlands KW - Akumal Mexico KW - sedimentary rocks KW - mineral composition KW - ecology KW - trace elements KW - chemical composition KW - construction KW - Quintana Roo Mexico KW - montmorillonite KW - soils KW - monitoring KW - aragonite KW - human activity KW - Yucatan Peninsula KW - pollution KW - powder method KW - clay minerals KW - calcite KW - aquifers KW - habitat KW - Mexico KW - wetlands KW - metals KW - sheet silicates KW - carbonate rocks KW - carbonates KW - permeability KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/51091514?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Geology+%28Berlin%29&rft.atitle=Investigation+of+subsurface+flow+constructed+wetlands+and+associated+geomaterial+resources+in+the+Akumal+and+Reforma+regions%2C+Quintana+Roo%2C+Mexico&rft.au=Krekeler%2C+Mark+P+S%3BProbst%2C+Pete%3BSamsonov%2C+Misha%3BTselepis%2C+Cynthia+M%3BBates%2C+William%3BKearns%2C+Lance+E%3BMaynard%2C+J+Barry&rft.aulast=Krekeler&rft.aufirst=Mark+P&rft.date=2007-12-01&rft.volume=53&rft.issue=4&rft.spage=709&rft.isbn=&rft.btitle=&rft.title=Environmental+Geology+%28Berlin%29&rft.issn=09430105&rft_id=info:doi/10.1007%2Fs00254-007-0684-z L2 - http://www.springerlink.com/content/1432-0495/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 56 N1 - Document feature - illus. incl. 4 tables, geol. sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - aggregate; Akumal Mexico; aquifer vulnerability; aquifers; aragonite; calcite; carbonate rocks; carbonates; chemical composition; clay minerals; constructed wetlands; construction; ecology; engineering properties; environmental analysis; ground water; habitat; human activity; lead; limestone; metals; Mexico; mineral composition; monitoring; montmorillonite; permeability; pollution; powder method; preferential flow; Quintana Roo Mexico; remediation; sedimentary rocks; sheet silicates; silicates; soils; trace elements; waste management; waste water; water management; water quality; wetlands; Yucatan Peninsula; zinc DO - http://dx.doi.org/10.1007/s00254-007-0684-z ER - TY - JOUR T1 - Water fluxes and their control on the terrestrial carbon balance; results from a stable isotope study on the Clyde watershed (Scotland) AN - 50852406; 2008-102014 AB - The gradients between precipitation and runoff quantities as well as their water isotopes were used to establish a water balance in the Clyde River Basin (Scotland). This study serves as an example for a European extreme with poorly vegetated land cover and high annual rainfall and presents novel water stable isotope techniques to separate evaporation, interception and transpiration with annual averages of 0.029 km (super 3) a (super -1) , 0.220 km (super 3) a (super -1) and 0.489 km (super 3) a (super -1) , respectively. Transpiration was further used to determine CO (sub 2) uptake of the entire basin and yielded an annual net primary production (NPP) of 352X10 (super 9) g C (Giga gram) or 185.2 g C m (super -2) . Compared to other temperate areas in the world, the Clyde Basin has only half the expected NPP. This lower value likely results from the type of vegetation cover, which consists mostly of grasslands. Subtracting the annual heterotrophic soil respiration flux (R (sub h) ) of 392 Gg (206.1 g C m (super -2) a (super -1) ) from the NPP yielded an annual Net Ecosystem Productivity (NEP) of -40 Gg C, thus showing the Clyde Watershed as a source of CO (sub 2) to the atmosphere. Despite the unusual character of the Clyde Watershed, the study shows that areas with predominant grass and scrub vegetation still have transpirational water losses that by far exceed those of pure evaporation and interception. This infers that vegetation can influence the continental water balances on time scales of years to decades. JF - Applied Geochemistry AU - Barth, Johannes A C AU - Freitag, H AU - Fowler, H J AU - Smith, A P AU - Ingle, C AU - Karim, A A2 - Fortin, Danielle A2 - Pichler, Thomas A2 - Saltikov, Chad Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 2684 EP - 2694 PB - Elsevier, Oxford-New York-Beijing VL - 22 IS - 12 SN - 0883-2927, 0883-2927 KW - isotopes KW - Europe KW - ecosystems KW - vegetation KW - stable isotopes KW - Great Britain KW - carbon dioxide KW - carbon KW - drainage basins KW - water content KW - geochemistry KW - hydrology KW - Western Europe KW - rainfall KW - isotope ratios KW - C-13/C-12 KW - water balance KW - hydrochemistry KW - evapotranspiration KW - United Kingdom KW - Scotland KW - Firth of Clyde KW - grasslands KW - Clyde River basin KW - 02D:Isotope geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50852406?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Geochemistry&rft.atitle=Water+fluxes+and+their+control+on+the+terrestrial+carbon+balance%3B+results+from+a+stable+isotope+study+on+the+Clyde+watershed+%28Scotland%29&rft.au=Barth%2C+Johannes+A+C%3BFreitag%2C+H%3BFowler%2C+H+J%3BSmith%2C+A+P%3BIngle%2C+C%3BKarim%2C+A&rft.aulast=Barth&rft.aufirst=Johannes+A&rft.date=2007-12-01&rft.volume=22&rft.issue=12&rft.spage=2684&rft.isbn=&rft.btitle=&rft.title=Applied+Geochemistry&rft.issn=08832927&rft_id=info:doi/10.1016%2Fj.apgeochem.2007.06.002 L2 - http://www.sciencedirect.com/science/journal/08832927 LA - English DB - GeoRef N1 - Conference title - Biogeochemical gradients; microbes, measurements, and modeling N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2008-01-01 N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - C-13/C-12; carbon; carbon dioxide; Clyde River basin; drainage basins; ecosystems; Europe; evapotranspiration; Firth of Clyde; geochemistry; grasslands; Great Britain; hydrochemistry; hydrology; isotope ratios; isotopes; rainfall; Scotland; stable isotopes; United Kingdom; vegetation; water balance; water content; Western Europe DO - http://dx.doi.org/10.1016/j.apgeochem.2007.06.002 ER - TY - JOUR T1 - Application of site-specific calibration data using the CALUX by XDS bioassay for dioxin-like chemicals in soil and sediment samples AN - 50649566; 2008-103291 JF - Environmental Science & Technology, ES & T AU - Dindal, Amy AU - Thompson, Elizabeth AU - Aume, Laura AU - Billets, Stephen Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 8376 EP - 8382 PB - American Chemical Society, Washington, DC VL - 41 IS - 24 SN - 0013-936X, 0013-936X KW - high-resolution methods KW - chemical analysis KW - pollutants KW - statistical analysis KW - pollution KW - mass spectra KW - calibration KW - dioxins KW - CALUX KW - environmental analysis KW - models KW - sample preparation KW - organic compounds KW - xenobiotic detection systems KW - solvents KW - soil pollution KW - chromatograms KW - XDS KW - sediments KW - quality control KW - chemically activated luciferase gene expression KW - spectra KW - geochemistry KW - 02C:Geochemistry of rocks, soils, and sediments KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50649566?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology%2C+ES+%26+T&rft.atitle=Application+of+site-specific+calibration+data+using+the+CALUX+by+XDS+bioassay+for+dioxin-like+chemicals+in+soil+and+sediment+samples&rft.au=Dindal%2C+Amy%3BThompson%2C+Elizabeth%3BAume%2C+Laura%3BBillets%2C+Stephen&rft.aulast=Dindal&rft.aufirst=Amy&rft.date=2007-12-01&rft.volume=41&rft.issue=24&rft.spage=8376&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology%2C+ES+%26+T&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes071303x L2 - http://pubs.acs.org/journals/esthag/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 15 N1 - PubXState - DC N1 - Document feature - 6 tables N1 - Last updated - 2012-06-07 N1 - CODEN - ESTHAG N1 - SubjectsTermNotLitGenreText - calibration; CALUX; chemical analysis; chemically activated luciferase gene expression; chromatograms; dioxins; environmental analysis; geochemistry; high-resolution methods; mass spectra; models; organic compounds; pollutants; pollution; quality control; sample preparation; sediments; soil pollution; solvents; spectra; statistical analysis; XDS; xenobiotic detection systems DO - http://dx.doi.org/10.1021/es071303x ER - TY - JOUR T1 - Field test of in situ soil amendments at the Tar Creek national priorities list Superfund site AN - 50615199; 2008-111273 JF - Journal of Environmental Quality AU - Brown, S L AU - Compton, H AU - Basta, N T Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 1627 EP - 1634 PB - American Society of Agronomy, [and] Crop Science Society of America, [and] Soil Science Society of America, Madison, WI VL - 36 IS - 6 SN - 0047-2425, 0047-2425 KW - United States KW - soils KW - water quality KW - electrical conductivity KW - Tar Creek Superfund Site KW - Ottawa County Oklahoma KW - water management KW - pollution KW - lead KW - diammonium phosphate KW - remediation KW - Oklahoma KW - soil pollution KW - metals KW - water treatment KW - biosolids KW - tailings KW - heavy metals KW - Superfund sites KW - field studies KW - ammonia compound KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50615199?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Quality&rft.atitle=Field+test+of+in+situ+soil+amendments+at+the+Tar+Creek+national+priorities+list+Superfund+site&rft.au=Brown%2C+S+L%3BCompton%2C+H%3BBasta%2C+N+T&rft.aulast=Brown&rft.aufirst=S&rft.date=2007-12-01&rft.volume=36&rft.issue=6&rft.spage=1627&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Quality&rft.issn=00472425&rft_id=info:doi/10.2134%2Fjeq2007.0018 L2 - http://jeq.scijournals.org/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2008-01-01 N1 - Number of references - 30 N1 - PubXState - WI N1 - Document feature - illus. incl. 4 tables N1 - Last updated - 2012-06-07 N1 - CODEN - JEVQAA N1 - SubjectsTermNotLitGenreText - ammonia compound; biosolids; diammonium phosphate; electrical conductivity; field studies; heavy metals; lead; metals; Oklahoma; Ottawa County Oklahoma; pollution; remediation; soil pollution; soils; Superfund sites; tailings; Tar Creek Superfund Site; United States; water management; water quality; water treatment DO - http://dx.doi.org/10.2134/jeq2007.0018 ER - TY - JOUR T1 - Agricultural pesticides and selected degradation products in five tidal regions and the main stem of Chesapeake Bay, USA AN - 50392767; 2009-067998 AB - Nutrients, sediment, and toxics from water sources and the surrounding airshed are major problems contributing to poor water quality in many regions of the Chesapeake Bay, an important estuary located in the mid-Atlantic region of the United States. During the early spring of 2000, surface water samples were collected for pesticide analysis from 18 stations spanning the Chesapeake Bay. In a separate effort from July to September of 2004, 61 stations within several tidal regions were characterized with respect to 21 pesticides and 11 of their degradation products. Three regions were located on the agricultural Delmarva Peninsula: The Chester, Nanticoke, and Pocomoke Rivers. Two regions were located on the more urban western shore: The Rhode and South Rivers and the Lower Mobjack Bay, including the Back and Poquoson Rivers. In both studies, herbicides and their degradation products were the most frequently detected chemicals. In 2000, atrazine and metolachlor were found at all 18 stations. In 2004, the highest parent herbicide concentrations were found in the upstream region of Chester River. The highest concentration for any analyte in these studies was for the ethane sulfonic acid of metolachlor (MESA) at 2,900 ng/L in the Nanticoke River. The degradation product MESA also had the greatest concentration of any analyte in the Pocomoke River (2,100 ng/L) and in the Chester River (1,200 ng/L). In the agricultural tributaries, herbicide degradation product concentrations were more strongly correlated with salinity than the parent herbicides. In the two nonagricultural watersheds on the western shore, no gradient in herbicide concentrations was observed, indicating the pesticide source to these areas was water from the Bay main stem. JF - Environmental Toxicology and Chemistry AU - McConnell, Laura L AU - Rice, Clifford P AU - Hapeman, Cathleen J AU - Drakeford, Leticia AU - Harman-Fetcho, Jennifer A AU - Bialek, Krystyna AU - Fulton, Michael H AU - Leight, Andrew K AU - Allen, Gregory AU - Collins, Chris Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 2567 EP - 2578 PB - SETAC, Pensacola, FL VL - 26 IS - 12 SN - 0730-7268, 0730-7268 KW - United States KW - water quality KW - Chesapeake Bay KW - degradation KW - rivers and streams KW - watersheds KW - triazines KW - intertidal environment KW - toxicity KW - sediments KW - drainage basins KW - Nanticoke River KW - depositional environment KW - estuarine environment KW - discharge KW - Delmarva Peninsula KW - hydrology KW - concentration KW - pollutants KW - herbicides KW - surface water KW - agriculture KW - pollution KW - metolachlor KW - Pocomoke River KW - Chester River KW - nutrients KW - organic compounds KW - atrazine KW - coastal environment KW - pesticides KW - land use KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50392767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=Agricultural+pesticides+and+selected+degradation+products+in+five+tidal+regions+and+the+main+stem+of+Chesapeake+Bay%2C+USA&rft.au=McConnell%2C+Laura+L%3BRice%2C+Clifford+P%3BHapeman%2C+Cathleen+J%3BDrakeford%2C+Leticia%3BHarman-Fetcho%2C+Jennifer+A%3BBialek%2C+Krystyna%3BFulton%2C+Michael+H%3BLeight%2C+Andrew+K%3BAllen%2C+Gregory%3BCollins%2C+Chris&rft.aulast=McConnell&rft.aufirst=Laura&rft.date=2007-12-01&rft.volume=26&rft.issue=12&rft.spage=2567&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/ L2 - http://www3.interscience.wiley.com/journal/122563640/home?CRETRY=1&SRETRY=0 LA - English DB - GeoRef N1 - Conference title - SETAC North America 26th annual meeting; symposium on Plant uptake of organic chemicals N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 33 N1 - PubXState - FL N1 - Document feature - illus. incl. 2 tables, sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - agriculture; atrazine; Chesapeake Bay; Chester River; coastal environment; concentration; degradation; Delmarva Peninsula; depositional environment; discharge; drainage basins; estuarine environment; herbicides; hydrology; intertidal environment; land use; metolachlor; Nanticoke River; nutrients; organic compounds; pesticides; Pocomoke River; pollutants; pollution; rivers and streams; sediments; surface water; toxicity; triazines; United States; water quality; watersheds ER - TY - JOUR T1 - An open-source community web site to support ground-water model testing AN - 50087663; 2010-019810 JF - Eos, Transactions, American Geophysical Union AU - Kraemer, S R AU - Bakker, M AU - Craig, J R AU - Anonymous Y1 - 2007/12// PY - 2007 DA - December 2007 SP - Abstract H13B EP - 1248 PB - American Geophysical Union, Washington, DC VL - 88 IS - 52, Suppl. SN - 0096-3941, 0096-3941 KW - models KW - laboratory studies KW - experimental studies KW - public policy KW - classification KW - data processing KW - Wiki Wiki KW - World Wide Web KW - ground water KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50087663?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Eos%2C+Transactions%2C+American+Geophysical+Union&rft.atitle=An+open-source+community+web+site+to+support+ground-water+model+testing&rft.au=Kraemer%2C+S+R%3BBakker%2C+M%3BCraig%2C+J+R%3BAnonymous&rft.aulast=Kraemer&rft.aufirst=S&rft.date=2007-12-01&rft.volume=88&rft.issue=52%2C+Suppl.&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Eos%2C+Transactions%2C+American+Geophysical+Union&rft.issn=00963941&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - American Geophysical Union 2007 fall meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - PubXState - DC N1 - Last updated - 2012-06-07 N1 - CODEN - EOSTAJ N1 - SubjectsTermNotLitGenreText - classification; data processing; experimental studies; ground water; laboratory studies; models; public policy; Wiki Wiki; World Wide Web ER - TY - JOUR T1 - High-resolution space-time ozone modeling for assessing trends AN - 36819989; 3510624 JF - Journal of the American Statistical Association AU - Sahu, Sujit K AU - Gelfand, Alan E AU - Holland, David M AD - University of Southampton ; Duke University ; National Exposure Research Laboratory Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 1221 EP - 1234 VL - 102 IS - 480 SN - 0162-1459, 0162-1459 KW - Sociology KW - Monte Carlo simulation KW - Environmentalism KW - Time KW - Model testing KW - Spatial analysis KW - Statistical analysis KW - Statistical methods KW - Space KW - Methodology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36819989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Statistical+Association&rft.atitle=High-resolution+space-time+ozone+modeling+for+assessing+trends&rft.au=Sahu%2C+Sujit+K%3BGelfand%2C+Alan+E%3BHolland%2C+David+M&rft.aulast=Sahu&rft.aufirst=Sujit&rft.date=2007-12-01&rft.volume=102&rft.issue=480&rft.spage=1221&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Statistical+Association&rft.issn=01621459&rft_id=info:doi/10.1198%2F016214507000000031 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12228 10919; 12224 971; 8160 8163; 8268 12265 3865 4025 10214 12224 971 12228 10919; 7994; 4348 4309; 12092; 12756; 12102 971 DO - http://dx.doi.org/10.1198/016214507000000031 ER - TY - JOUR T1 - A Quantitative Real-Time Polymerase Chain Reaction Method for the Analysis of Vitellogenin Transcripts in Model and Nonmodel Fish Species AN - 21034081; 7754542 AB - The measurement of vitellogenin (vtg) gene transcription has been shown to be a reliable indicator of exposure to estrogenic compounds. Unfortunately, the relatively poor molecular characterization of North American fish species has hindered its application to a larger number of ecologically important species. The current research aimed to demonstrate specific amplification of vtg gene transcripts in three model (zebrafish, rainbow trout, and medaka) and six nonmodel (emerald shiner, pearl dace, smallmouth bass, creek chub, white sucker, and golden redhorse) fish species. Quantitative polymerase chain reaction (QPCR) primers for model species were designed from publicly available vtg sequences. Successful amplification of vtg was demonstrated in fish exposed to 17alpha-ethinylestradiol (EE sub(2)) for all model species. Vitellogenin primers for selected nonmodel species were designed from published sequences of closely related species. Multiple primers were developed targeting different regions of the vtg gene. The successful amplification of vtg was confirmed through size and sequence analysis for all nonmodel species with the exception of the white sucker, in which amplifications failed. Furthermore, QPCR primers and conditions were quantitative over five orders of magnitude in at least one species (pearl dace) exposed to 5 ng/L of EE sub(2) for 24 h. The selected species are found in a wide array of ecological habitats that span the United States. Inclusion of vtg transcriptional analysis for wild, ecologically relevant fish in monitoring studies may aid in understanding the extent of estrogenic exposure in aquatic ecosystems across the United States. JF - Environmental Toxicology and Chemistry AU - Biales, Adam D AU - Bencic, David C AU - Lazorchak, Jim L AU - Lattier, David L AD - U.S. Environmental Protection Agency, National Exposure Research Laboratory, Ecological Exposure Research Division, 26 West Martin Luther King Drive, Mail Stop 642, Cincinnati, Ohio 45268 Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 2679 EP - 2686 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 26 IS - 12 SN - 0730-7268, 0730-7268 KW - Pollution Abstracts; Toxicology Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Real time KW - Vitellogenin KW - Endocrine disrupting compounds KW - Estrogen KW - Primers KW - Oryzias latipes KW - Nucleotide sequence KW - Freshwater fish KW - Streams KW - Models KW - Sex hormones KW - Exposure KW - Polymerase chain reaction KW - Toxicology KW - Modelling KW - Phylogeny KW - Geochemistry KW - Transcription KW - Oncorhynchus mykiss KW - Aquatic ecosystems KW - Habitat KW - Model Studies KW - Pearls KW - Danio rerio KW - USA KW - Trout KW - Water Pollution Effects KW - Fish KW - Monitoring KW - aquatic ecosystems KW - Sucker KW - Chubs KW - estrogens KW - P 2000:FRESHWATER POLLUTION KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21034081?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=A+Quantitative+Real-Time+Polymerase+Chain+Reaction+Method+for+the+Analysis+of+Vitellogenin+Transcripts+in+Model+and+Nonmodel+Fish+Species&rft.au=Biales%2C+Adam+D%3BBencic%2C+David+C%3BLazorchak%2C+Jim+L%3BLattier%2C+David+L&rft.aulast=Biales&rft.aufirst=Adam&rft.date=2007-12-01&rft.volume=26&rft.issue=12&rft.spage=2679&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F07-101.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Phylogeny; Nucleotide sequence; Geochemistry; Transcription; Polymerase chain reaction; Freshwater fish; Toxicology; Modelling; Sex hormones; Pearls; Vitellogenin; Primers; Habitat; Aquatic ecosystems; Models; aquatic ecosystems; estrogens; Trout; Exposure; Water Pollution Effects; Fish; Monitoring; Streams; Chubs; Sucker; Model Studies; Danio rerio; Oryzias latipes; Oncorhynchus mykiss; USA DO - http://dx.doi.org/10.1897/07-101.1 ER - TY - JOUR T1 - Avoiding Tragedies of the Intellectual Commons through Integrated Impact Assessments AN - 20900683; 8149322 AB - This paper suggests that an ex ante assessment of future social, environmental, and economic impacts - i.e., an Integrated Impact Assessment, as advocated by the European Commission - might be precisely the sort of interdisciplinary and numerate analytical tool to give administrative reality to the principles of Integrated Water Resources Management (IWRM). For these assessments to be an effective administrative tool for IWRM, the general public must be able to use them to transparently compare environmental, social, and economic values and to compel states to pursue policies consistent with their underlying analyses. In making this argument, this paper compares the use of integrated assessments by the European Union and the United States in addressing mercury pollution. JF - Water Resources Management AU - Pascual, Pasky AD - CREM, US EPA, 1200 Pennsylvania Avenue, MC-8701F, Washington, DC, 20460, USA, pascual.pasky@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 2005 EP - 2013 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 21 IS - 12 SN - 0920-4741, 0920-4741 KW - Pollution Abstracts; Sustainability Science Abstracts; Water Resources Abstracts KW - USA KW - Resource management KW - European Union KW - Assessments KW - Mercury KW - Socioeconomics KW - Water resources KW - Water Resources Management KW - Economic Impact KW - P 9000:ENVIRONMENTAL ACTION KW - M3 1010:Issues in Sustainable Development KW - SW 3020:Sources and fate of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20900683?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Resources+Management&rft.atitle=Avoiding+Tragedies+of+the+Intellectual+Commons+through+Integrated+Impact+Assessments&rft.au=Pascual%2C+Pasky&rft.aulast=Pascual&rft.aufirst=Pasky&rft.date=2007-12-01&rft.volume=21&rft.issue=12&rft.spage=2005&rft.isbn=&rft.btitle=&rft.title=Water+Resources+Management&rft.issn=09204741&rft_id=info:doi/10.1007%2Fs11269-006-9130-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Resource management; Water resources; Socioeconomics; Mercury; Assessments; Water Resources Management; Economic Impact; USA; European Union DO - http://dx.doi.org/10.1007/s11269-006-9130-3 ER - TY - JOUR T1 - Geographic structure, genetic diversity and source tracking of Spartina alterniflora AN - 20765412; 7992656 AB - Aim To examine the distribution and structure of genetic variation among native Spartina alterniflora and to characterize the evolutionary mechanisms underlying the success of non-native S. alterniflora. Location Intertidal marshes along the Atlantic, Gulf and Pacific coasts of North America. Methods amova, parsimony analysis, haplotype networks of chloroplast DNA (cpDNA) sequences, neighbour-joining analysis, Bayesian analysis of population structure, and individual assignment testing were used. Results Low levels of gene flow and geographic patterns of genetic variation were found among native S. alterniflora from the Atlantic and Gulf coasts of North America. The distribution of cpDNA haplotypes indicates that Atlantic coast S. alterniflora are subdivided into 'northern' and 'southern' groups. Variation observed at microsatellite loci further suggests that mid-Atlantic S. alterniflora are differentiated from S. alterniflora found in southern Atlantic and New England coastal marshes. Comparisons between native populations on the Atlantic and Gulf coasts and non-native Pacific coast populations substantiate prior studies demonstrating reciprocal interspecific hybridization in San Francisco Bay. Our results corroborate historical evidence that S. alterniflora was introduced into Willapa Bay from multiple source populations. However, we found that some Willapa Bay S. alterniflora are genetically divergent from putative sources, probably as a result of admixture following secondary contact among previously allopatric native populations. We further recovered evidence in support of models suggesting that S. alterniflora has secondarily spread within Washington State, from Willapa Bay to Grays Harbor. Main conclusions Underlying genetic structure has often been cited as a factor contributing to ecological variation of native S. alterniflora. Patterns of genetic structure within native S. alterniflora may be the result of environmental differences among biogeographical provinces, of migration barriers, or of responses to historical conditions. Interactions among these factors, rather than one single factor, may best explain the distribution of genetic variation among native S. alterniflora. Comprehensive genetic comparisons of native and introduced populations can illustrate how biological invasions may result from dramatically different underlying factors - some of which might otherwise go unrecognized. Demonstrating that invasions can result from several independent or interacting mechanisms is important for improving risk assessment and future forecasting. Further research on S. alterniflora not only may clarify what forces structure native populations, but also may improve the management of non-native populations by enabling post-introduction genetic changes and the rapid evolution of life-history traits to be more successfully exploited. JF - Journal of Biogeography AU - Blum, Michael J AU - Jun Bando, K AU - Katz, M AU - Strong, Donald R AD - US Environmental Protection Agency, National Exposure Research Laboratory, Molecular Ecology Research Branch, Cincinnati, OH 45268, USA, mjblum@tulane.edu Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 2055 EP - 2069 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 34 IS - 12 SN - 0305-0270, 0305-0270 KW - Genetics Abstracts; ASFA Aquaculture Abstracts; Ecology Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Admixture KW - biological invasions KW - hybridization KW - intertidal KW - North America KW - phylogeography KW - secondary spread KW - smooth cordgrass KW - Spartina alterniflora KW - Risk assessment KW - Geographical distribution KW - Bayesian analysis KW - Nucleotide sequence KW - Genetic diversity KW - ANW, USA, New England KW - Migration KW - Models KW - INE, USA, Washington, Willapa Bay KW - Population genetics KW - Haplotypes KW - Gene flow KW - Invasions KW - Coasts KW - Mathematical models KW - Biogeography KW - Interspecific hybridization KW - Microsatellites KW - Aquatic plants KW - Population studies KW - Marshes KW - Coastal zone KW - Chloroplast DNA KW - INE, USA, Washington, Grays Harbor KW - DNA KW - INE, USA, California, San Francisco Bay KW - Population structure KW - Genetic structure KW - Evolution KW - Dispersion KW - Q3 08581:Aquaculture: General KW - Q1 08581:General KW - D 04040:Ecosystem and Ecology Studies KW - G 07750:Ecological & Population Genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20765412?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Biogeography&rft.atitle=Geographic+structure%2C+genetic+diversity+and+source+tracking+of+Spartina+alterniflora&rft.au=Blum%2C+Michael+J%3BJun+Bando%2C+K%3BKatz%2C+M%3BStrong%2C+Donald+R&rft.aulast=Blum&rft.aufirst=Michael&rft.date=2007-12-01&rft.volume=34&rft.issue=12&rft.spage=2055&rft.isbn=&rft.btitle=&rft.title=Journal+of+Biogeography&rft.issn=03050270&rft_id=info:doi/10.1111%2Fj.1365-2699.2007.01764.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Population genetics; Geographical distribution; Coastal zone; Biogeography; Nucleotide sequence; DNA; Aquatic plants; Population structure; Dispersion; Risk assessment; Mathematical models; Bayesian analysis; Microsatellites; Interspecific hybridization; Population studies; Genetic diversity; Marshes; Migration; Models; Chloroplast DNA; Haplotypes; Gene flow; Invasions; Genetic structure; Evolution; Coasts; Spartina alterniflora; INE, USA, Washington, Willapa Bay; INE, USA, Washington, Grays Harbor; INE, USA, California, San Francisco Bay; ANW, USA, New England DO - http://dx.doi.org/10.1111/j.1365-2699.2007.01764.x ER - TY - JOUR T1 - Evaluation of three watershed-scale pesticide environmental transport and fate models AN - 20757176; 7956864 AB - The U.S. Environmental Protection Agency (USEPA) Office of Pesticide Programs (OPP) has completed an evaluation of three watershed-scale simulation models for potential use in Food Quality Protection Act pesticide drinking water exposure assessments. The evaluation may also guide OPP in identifying computer simulation tools that can be used in performing aquatic ecological exposure assessments. Models selected for evaluation were the Soil Water Assessment Tool (SWAT), the Nonpoint Source Model (NPSM), a modified version of the Hydrologic Simulation Program-Fortran (HSPF), and the Pesticide Root Zone Model-Riverine Water Quality (PRZM-RIVWQ) model. Simulated concentrations of the pesticides atrazine, metolachlor, and trifluralin in surface water were compared with field data monitored in the Sugar Creek watershed of Indiana's White River basin by the National Water Quality Assessment (NAWQA) program. The evaluation not only provided USEPA with experience in using watershed models for estimating pesticide concentration in flowing water but also led to the development of improved statistical techniques for assessing model accuracy. Further, it demonstrated the difficulty of representing spatially and temporally variable soil, weather, and pesticide applications with relatively infrequent, spatially fixed, point estimates. It also demonstrated the value of using monitoring and modeling as mutually supporting tools and pointed to the need to design monitoring programs that support modeling. JF - Journal of the American Water Resources Association AU - Parker, R AU - Arnold, J G AU - Barrett, M AU - Burns, L AU - Carrubba, L AU - Neitsch, S L AU - Snyder, N J AU - Srinivasan, R AD - USEPA Office of Pesticide Programs, Washington, DC 20460, USA, parker.ronald@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 1424 EP - 1443 VL - 43 IS - 6 SN - 1093-474X, 1093-474X KW - Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts; Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - water quality KW - Water resources KW - Watersheds KW - Water quality KW - Evaluation KW - Soil KW - Hydrologic Models KW - Agricultural Chemicals KW - Exposure KW - Weather KW - Water Quality KW - River basins KW - Nonpoint pollution KW - Environmental protection KW - USA, Indiana KW - EPA KW - Numerical simulations KW - Monitoring KW - Soil moisture KW - Environment management KW - Pollution monitoring KW - Surface water KW - Statistical analysis KW - USA, Arkansas, White R. KW - Assessments KW - Simulation KW - Herbicides KW - Identification KW - Water pollution KW - USA KW - Atrazine KW - Pesticides KW - Trifluralin KW - Drinking water KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - M2 556.14:Infiltration/Soil Moisture (556.14) KW - Q5 08522:Protective measures and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20757176?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Evaluation+of+three+watershed-scale+pesticide+environmental+transport+and+fate+models&rft.au=Parker%2C+R%3BArnold%2C+J+G%3BBarrett%2C+M%3BBurns%2C+L%3BCarrubba%2C+L%3BNeitsch%2C+S+L%3BSnyder%2C+N+J%3BSrinivasan%2C+R&rft.aulast=Parker&rft.aufirst=R&rft.date=2007-12-01&rft.volume=43&rft.issue=6&rft.spage=1424&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2007.00101.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Pollution monitoring; Pesticides; Water resources; River basins; Identification; Water quality; Watersheds; Environment management; Water pollution; Numerical simulations; Statistical analysis; Soil moisture; Environmental protection; water quality; Weather; Surface water; Simulation; Herbicides; Nonpoint pollution; Soil; EPA; Atrazine; Trifluralin; Drinking water; Evaluation; Agricultural Chemicals; Hydrologic Models; Assessments; Exposure; Water Quality; Monitoring; USA, Indiana; USA, Arkansas, White R.; USA DO - http://dx.doi.org/10.1111/j.1752-1688.2007.00101.x ER - TY - JOUR T1 - Mode of action as a determining factor in additivity models for chemical mixture risk assessment AN - 20724836; 7938623 AB - It is inevitable that in a lifetime humans will be exposed to a diverse array of chemical mixtures through occupational, recreational, and/or domestic activities. These mixtures may be simple, consisting of two or more definable compounds, or may be more complex containing several hundred related congeners and/or unrelated compounds. Due to a paucity of mixtures toxicity data, the estimation of risk of adverse health effects associated with mixtures typically comes from empirical observations of single chemical exposures. Under existing policy, characterizing the relative contribution of each compound depends on identification of the target organ or tissue dose, mode of action, and duration of effect. Currently, there is no consensus on what constitutes a toxic mode or mechanism of action, nor is there a universally accepted framework to determine similarity or independence of mode of action for mixtures risk assessment. This lack of a comprehensive classification paradigm for mode or mechanism of toxic action continues to be a major rate-limiting step in the advancement of mixtures risk assessment. A potential unifying approach to characterizing mode of action involves critical evaluation of data at all levels of biological organization for identification of 'key events'. Development of a biologically plausible weight of evidence description of the key obligatory steps in mechanistic pathways may facilitate selection of the most appropriate component-based mixtures risk assessment approach. Hypothetical case studies are presented to demonstrate the quantitative impact of the choice of dose addition or response addition to estimate risk. JF - Regulatory Toxicology and Pharmacology AU - Lambert, J C AU - Lipscomb, J C AD - Office of Research and Development, National Center for Environmental Assessment, 26 West Martin Luther King Drive (A-110), Cincinnati, OH 45268, USA, Lipscomb.john@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 183 EP - 194 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 49 IS - 3 SN - 0273-2300, 0273-2300 KW - Risk Abstracts; Toxicology Abstracts KW - case studies KW - Risk assessment KW - Classification KW - Recreation areas KW - classification KW - Congeners KW - Toxicity KW - Organs KW - Models KW - R2 23080:Industrial and labor KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20724836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+Toxicology+and+Pharmacology&rft.atitle=Mode+of+action+as+a+determining+factor+in+additivity+models+for+chemical+mixture+risk+assessment&rft.au=Lambert%2C+J+C%3BLipscomb%2C+J+C&rft.aulast=Lambert&rft.aufirst=J&rft.date=2007-12-01&rft.volume=49&rft.issue=3&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Regulatory+Toxicology+and+Pharmacology&rft.issn=02732300&rft_id=info:doi/10.1016%2Fj.yrtph.2007.07.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Classification; Congeners; Toxicity; Models; case studies; Recreation areas; classification; Organs DO - http://dx.doi.org/10.1016/j.yrtph.2007.07.002 ER - TY - JOUR T1 - Ft. McHenry tunnel study: Source profiles and mercury emissions from diesel and gasoline powered vehicles AN - 20690321; 8182562 AB - During the fall of 1998, the US Environmental Protection Agency and the Florida Department of Environmental Protection sponsored a 7-day study at the Ft. McHenry tunnel in Baltimore, MD with the objective of obtaining PM sub(2) sub(.) sub(5) vehicle source profiles for use in atmospheric mercury source apportionment studies. PM sub(2) sub(.) sub(5) emission profiles from gasoline and diesel powered vehicles were developed from analysis of trace elements, polycyclic aromatic hydrocarbons (PAH), and condensed aliphatic hydrocarbons. PM sub(2) sub(.) sub(5) samples were collected using commercially available sampling systems and were extracted and analyzed using conventional well-established methods. Both inorganic and organic profiles were sufficiently unique to mathematically discriminate the contributions from each source type using a chemical mass balance source apportionment approach. However, only the organic source profiles provided unique PAH tracers (e.g., fluoranthene, pyrene, and chrysene) for diesel combustion that could be used to identify source contributions generated using multivariate statistical receptor modeling approaches. In addition, the study found significant emission of gaseous elemental mercury (Hg super(0)), divalent reactive gaseous mercury (RGM), and particulate mercury (Hg(p)) from gasoline but not from diesel powered motor vehicles. Fuel analysis supported the tunnel measurement results showing that total mercury content in all grades of gasoline (284+ /-108ngL super(-) super(1)) was substantially higher than total mercury content in diesel fuel (62+/-37ngL super(-) super(1)) collected contemporaneously at local Baltimore retailers. JF - Atmospheric Environment AU - Landis AU - Lewis, C W AU - Stevens, R K AU - Keeler, G J AU - Dvonch, J T AU - Tremblay, R T AD - Office of Research and Development, Research Triangle Park, NC 27709, USA, landis.matthew@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 8711 EP - 8724 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 38 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - USA, Florida KW - Gasoline KW - Fuels KW - Statistical analysis KW - Mercury sources KW - USA, Maryland, Baltimore KW - Particulates KW - Trace elements KW - Atmospheric pollution by diesel engines KW - Tracers KW - pyrene KW - Emissions KW - Trace elements in atmosphere KW - Polycyclic aromatic hydrocarbons in atmosphere KW - Particle size KW - Mercury in the atmosphere KW - Atmospheric pollution KW - Atmospheric pollution by motor vehicles KW - Polycyclic aromatic hydrocarbon emissions KW - Environmental protection KW - Combustion KW - EPA KW - Particulate matter emissions KW - Mercury emissions KW - polycyclic aromatic hydrocarbons KW - Mercury KW - aromatic hydrocarbons KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20690321?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Ft.+McHenry+tunnel+study%3A+Source+profiles+and+mercury+emissions+from+diesel+and+gasoline+powered+vehicles&rft.au=Landis%3BLewis%2C+C+W%3BStevens%2C+R+K%3BKeeler%2C+G+J%3BDvonch%2C+J+T%3BTremblay%2C+R+T&rft.aulast=Landis&rft.aufirst=&rft.date=2007-12-01&rft.volume=41&rft.issue=38&rft.spage=8711&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.07.028 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Mercury in the atmosphere; Atmospheric pollution; Atmospheric pollution models; Statistical analysis; Mercury sources; Atmospheric pollution by motor vehicles; Environmental protection; Polycyclic aromatic hydrocarbon emissions; Atmospheric pollution by diesel engines; Particulate matter emissions; Mercury emissions; Trace elements in atmosphere; Polycyclic aromatic hydrocarbons in atmosphere; Particle size; Gasoline; Fuels; Particulates; Combustion; Trace elements; EPA; Tracers; pyrene; Emissions; Mercury; polycyclic aromatic hydrocarbons; aromatic hydrocarbons; USA, Florida; USA, Maryland, Baltimore DO - http://dx.doi.org/10.1016/j.atmosenv.2007.07.028 ER - TY - JOUR T1 - An evaluation of the protein mass of particulate matter AN - 20689434; 8182446 AB - This research study provides the characterization of mass percent of protein-based particulate matter in total ambient particulate matter collected in a metropolitan area of NC. The project determined the percentages of protein-based ambient bioaerosols for particles in the 2.5-10 mu m range and for particles in the range of 2.5 mu m or less in 298 samples taken over a six-month period. The analysis of total protein mass was used as an all-inclusive indicator of biologically based aerosols. These organic bioaerosols may have nucleated with inorganic non-biological aerosols, or they may be combined with inert aerosols. The source of these bioaerosols may be any combination of pollen, mold, bacteria, insect debris, fecal matter, or dander, and they may induce irritational, allergic, infectious, and chemical responses in exposed individuals. Ambient samples of PM sub(2) sub(.) sub(5) and PM sub(1) sub(0) sub(-) sub(2) sub(.) sub(5) were analyzed for gravimetric mass and total protein mass. The results for 19 of 24 sample periods indicated that between 1% and 4% of PM sub(1) sub(0) sub(-) sub(2) sub(.) sub(5) and between 1% and 2% of PM sub(2) sub(.) sub(5) mass concentrations were made of ambient protein bioaerosols. (The remaining 5 of 24 sample periods yielded protein results which were below detectable limits.) JF - Atmospheric Environment AU - Menetrez, MY AU - Foarde, K K AU - Dean, T R AU - Betancourt, DA AU - Moore, SA AD - Office of Research and Development, National Risk Management Research Laboratory, Air Pollution Prevention and Control Division, Research Triangle Park, NC 27711, USA, menetrez.marc@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 8264 EP - 8274 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 37 SN - 1352-2310, 1352-2310 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Particle size KW - Aerosols KW - Bioaerosols KW - Atmospheric pollution KW - Particulates KW - Particulate matter in atmosphere KW - pollen KW - Proteins KW - metropolitan areas KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20689434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=An+evaluation+of+the+protein+mass+of+particulate+matter&rft.au=Menetrez%2C+MY%3BFoarde%2C+K+K%3BDean%2C+T+R%3BBetancourt%2C+DA%3BMoore%2C+SA&rft.aulast=Menetrez&rft.aufirst=MY&rft.date=2007-12-01&rft.volume=41&rft.issue=37&rft.spage=8264&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.06.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Particulate matter in atmosphere; Atmospheric pollution; Bioaerosols; Particle size; Aerosols; pollen; Proteins; Particulates; metropolitan areas DO - http://dx.doi.org/10.1016/j.atmosenv.2007.06.021 ER - TY - JOUR T1 - Estimates of the contributions of biogenic and anthropogenic hydrocarbons to secondary organic aerosol at a southeastern US location AN - 20689415; 8182443 AB - An organic tracer-based method containing laboratory and field study components was used to estimate the secondary organic aerosol (SOA) contributions of biogenic and anthropogenic hydrocarbons to ambient organic carbon (OC) concentrations in PM sub(2) sub(.) sub(5) during 2003 in Research Triangle Park, NC. In the laboratory, smog chamber experiments were conducted where isoprene, alpha -pinene, beta -caryophyllene, and toluene were individually irradiated in the presence of NO sub(X). In each experiment, SOA was collected and analyzed for potential tracer compounds, whose concentrations were used to calculate a mass fraction of tracer compounds for each hydrocarbon. In the field, 33 PM sub(2) sub(.) sub(5) samples were collected and analyzed for (1) tracer compounds observed in the laboratory irradiations, (2) levoglucosan, a biomass burning tracer, and (3) total OC. For each of the four hydrocarbons, the SOA contributions to ambient OC concentrations were estimated using the tracer concentrations and the laboratory-derived mass fractions. The estimates show SOA formation from isoprene, alpha -pinene, beta -caryophyllene, and toluene contributed significantly to the ambient OC concentrations. The relative contributions were highly seasonal with biomass burning in the winter accounting for more than 50% of the OC concentrations, while SOA contributions remained low. However, during the 6-month period between May and October, SOA from the precursor hydrocarbons contributed more than 40% of the measured OC concentration. Although the tracer-based method is subject to considerable uncertainty due to the simplification of replacing the complex set of chemical reactions responsible for SOA with a laboratory-derived single-valued mass fraction, the results suggest this approach can be used to identify major sources of SOA which can assist in the development of air quality models. JF - Atmospheric Environment AU - Kleindienst, TE AU - Jaoui, M AU - Lewandowski, M AU - Offenberg, J H AU - Lewis, C W AU - Bhave, P V AU - Edney, E O AD - National Exposure Research Laboratory, Research Triangle Park, NC 27711, USA, kleindienst.tad@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 8288 EP - 8300 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 37 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Combustion products KW - Toluene KW - Organic carbon KW - Air quality KW - Tracers KW - Particulate matter in atmosphere KW - Sulfur dioxide KW - Seasonal variations KW - Particle size KW - Aerosols KW - Smog chambers KW - Atmospheric pollution KW - Laboratory testing KW - anthropogenic factors KW - Organic aerosols in atmosphere KW - Biomass KW - burning KW - Air quality models KW - USA KW - Chemical reactions KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20689415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Estimates+of+the+contributions+of+biogenic+and+anthropogenic+hydrocarbons+to+secondary+organic+aerosol+at+a+southeastern+US+location&rft.au=Kleindienst%2C+TE%3BJaoui%2C+M%3BLewandowski%2C+M%3BOffenberg%2C+J+H%3BLewis%2C+C+W%3BBhave%2C+P+V%3BEdney%2C+E+O&rft.aulast=Kleindienst&rft.aufirst=TE&rft.date=2007-12-01&rft.volume=41&rft.issue=37&rft.spage=8288&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.06.045 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Particulate matter in atmosphere; Smog chambers; Atmospheric pollution; Organic aerosols in atmosphere; Air quality models; Particle size; Aerosols; Laboratory testing; Combustion products; anthropogenic factors; Toluene; Organic carbon; Air quality; burning; Biomass; Tracers; Sulfur dioxide; Chemical reactions; Seasonal variations; USA DO - http://dx.doi.org/10.1016/j.atmosenv.2007.06.045 ER - TY - JOUR T1 - The effects of roadside structures on the transport and dispersion of ultrafine particles from highways AN - 20670377; 8182457 AB - Understanding local-scale transport and dispersion of pollutants emitted from traffic sources is important for urban planning and air quality assessments. Predicting pollutant concentration patterns in complex environments depends on accurate representations of local features (e.g., noise barriers, trees, buildings) affecting near-field air flows. This study examined the effects of roadside barriers on the flow patterns and dispersion of pollutants from a high-traffic highway in Raleigh, North Carolina, USA. The effects of the structures were analyzed using the Quick Urban & Industrial Complex (QUIC) model, an empirically based diagnostic tool which simulates fine-scale wind field and dispersion patterns around obstacles. Model simulations were compared with the spatial distributions of ultrafine particles (UFP) from vehicular emissions measured using a passenger van equipped with a Differential Mobility Analyzer/Condensation Particle Counter. The field site allowed for an evaluation of pollutant concentrations in open terrain, with a noise barrier present near the road, and with a noise barrier and vegetation present near the road. Results indicated that air pollutant concentrations near the road were generally higher in open terrain situations with no barriers present; however, concentrations for this case decreased faster with distance than when roadside barriers were present. The presence of a noise barrier and vegetation resulted in the lowest downwind pollutant concentrations, indicating that the plume under this condition was relatively uniform and vertically well-mixed. Comparison of the QUIC model with the mobile UFP measurements indicated that QUIC reasonably represented pollutant transport and dispersion for each of the study configurations. JF - Atmospheric Environment AU - Bowker, GE AU - Baldauf, R AU - Isakov, V AU - Khlystov, A AU - Petersen, W AD - Office of Research and Development, National Risk Management Research Laboratory, USA, baldauf.richard@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 8128 EP - 8139 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 37 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - USA, North Carolina KW - Atmospheric pollution models KW - Spatial distribution KW - Trees KW - Acoustic waves KW - Pollution dispersion KW - Air quality KW - Particulates KW - Wind fields KW - Urban planning KW - spatial distribution KW - air flow KW - Noise pollution KW - Highways KW - Wind KW - Atmospheric pollution KW - roadsides KW - Noise levels KW - Vegetation KW - Buildings KW - Air pollution KW - traffic KW - Numerical simulations KW - Condensation KW - Dispersion models KW - Dispersion of particles KW - USA, North Carolina, Raleigh KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20670377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=The+effects+of+roadside+structures+on+the+transport+and+dispersion+of+ultrafine+particles+from+highways&rft.au=Bowker%2C+GE%3BBaldauf%2C+R%3BIsakov%2C+V%3BKhlystov%2C+A%3BPetersen%2C+W&rft.aulast=Bowker&rft.aufirst=GE&rft.date=2007-12-01&rft.volume=41&rft.issue=37&rft.spage=8128&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.06.064 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution models; Atmospheric pollution; Numerical simulations; Spatial distribution; Acoustic waves; Air quality; Condensation; Noise pollution; Dispersion of particles; Dispersion models; Wind fields; Trees; roadsides; Pollution dispersion; Noise levels; Vegetation; Particulates; Buildings; Air pollution; Urban planning; air flow; spatial distribution; traffic; Highways; Wind; USA, North Carolina; USA, North Carolina, Raleigh DO - http://dx.doi.org/10.1016/j.atmosenv.2007.06.064 ER - TY - JOUR T1 - Evaluation of the Community Multiscale Air Quality (CMAQ) model version 4.5: Sensitivities impacting model performance AN - 20669593; 8182821 AB - This study examines ozone (O sub(3)) predictions from the Community Multiscale Air Quality (CMAQ) model version 4.5 and discusses potential factors influencing the model results. Daily maximum 8-h average O sub(3) levels are largely underpredicted when observed O sub(3) levels are above 85ppb and overpredicted when they are below 35ppb. Using a clustering approach, model performance was examined separately for several different synoptic regimes. Under the most common synoptic conditions of a typical summertime Bermuda High setup, the model showed good overall performance for O sub(3), while associations have been identified here between other, less frequent, synoptic regimes and the O sub(3) overprediction and underprediction biases. A sensitivity test between the CB-IV and CB05 chemical mechanisms showed that predictions of daily maximum 8-h average O sub(3) using CB05 were on average 7.3% higher than those using CB-IV. Boundary condition (BC) sensitivity tests show that the overprediction biases at low O sub(3) levels are more sensitive to the BC O sub(3) levels near the surface than BC concentrations aloft. These sensitivity tests also show the model performance for O sub(3) improved when using the global GEOS-CHEM BCs instead of default profiles. Simulations using the newest version of the CMAQ model (v4.6) showed a small improvement in O sub(3) predictions, particularly when vertical layers were not collapsed. Collectively, the results suggest that key synoptic weather patterns play a leading role in the prediction biases, and more detailed study of these episodes are needed to identify further modeling improvements. JF - Atmospheric Environment AU - Appel, K W AU - Gilliland, AB AU - Sarwar, G AU - Gilliam, R C AD - Air Resources Laboratory, National Oceanic and Atmospheric Administration, U.S. EPA, 109 T.W. Alexander Drive, Research Triangle Park, NC 27711, USA, Wyat.Appel@noaa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 9603 EP - 9615 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 40 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Weather KW - Atmospheric pollution KW - Simulation KW - Air quality KW - ANW, Atlantic, Bermuda KW - Boundary conditions KW - boundary conditions KW - Ozone in troposphere KW - Numerical simulations KW - Ozone KW - Synoptic conditions KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20669593?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Evaluation+of+the+Community+Multiscale+Air+Quality+%28CMAQ%29+model+version+4.5%3A+Sensitivities+impacting+model+performance&rft.au=Appel%2C+K+W%3BGilliland%2C+AB%3BSarwar%2C+G%3BGilliam%2C+R+C&rft.aulast=Appel&rft.aufirst=K&rft.date=2007-12-01&rft.volume=41&rft.issue=40&rft.spage=9603&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.08.044 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Ozone in troposphere; Atmospheric pollution; Numerical simulations; Air quality; Boundary conditions; Synoptic conditions; Ozone; Weather; Simulation; boundary conditions; ANW, Atlantic, Bermuda DO - http://dx.doi.org/10.1016/j.atmosenv.2007.08.044 ER - TY - JOUR T1 - Calculating physical properties of organic compounds for environmental modeling from molecular structure AN - 20669299; 8147573 AB - Mathematical models for predicting the transport and fate of pollutants in the environment require reactivity parameter values - that is the value of the physical and chemical constants that govern reactivity. Although empirical structure-activity relationships have been developed that allow estimation of some constants, such relationships are generally valid only within limited families of chemicals. The computer program, SPARC, uses computational algorithms based on fundamental chemical structure theory to estimate a large number of chemical reactivity parameters and physical properties for a wide range of organic molecules strictly from molecular structure. Resonance models were developed and calibrated using measured light absorption spectra, whereas electrostatic interaction models were developed using measured ionization pK sub(a)s in water. Solvation models (i.e., dispersion, induction, H-bonding, etc.) have been developed using various measured physical properties data. At the present time, SPARC's physical property models can predict vapor pressure and heat of vaporization (as a function of temperature), boiling point (as a function of pressure), diffusion coefficient (as a function of pressure and temperature), activity coefficient, solubility, partition coefficient and chromatographic retention time as a function of solvent and temperature. This prediction capability crosses chemical family boundaries to cover a broad range of organic compounds. JF - Journal of Computer-Aided Molecular Design AU - Hilal, SH AU - Saravanaraj, AN AU - Whiteside, T AU - Carreira, LA AD - US Environmental Protection Agency, 960 College Station Road, Athens, GA, USA, hilal.said@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 693 EP - 708 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 21 IS - 12 SN - 0920-654X, 0920-654X KW - Biotechnology and Bioengineering Abstracts KW - Temperature effects KW - Protein kinase A KW - Mathematical models KW - Solubility KW - Solvents KW - Algorithms KW - Electrostatic properties KW - Computer applications KW - Light effects KW - Computer programs KW - Vapors KW - Pollutants KW - Heat KW - Boiling KW - Boundaries KW - Osteonectin KW - Organic compounds KW - Diffusion coefficient KW - Pressure KW - Ionization KW - Structure-activity relationships KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20669299?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Computer-Aided+Molecular+Design&rft.atitle=Calculating+physical+properties+of+organic+compounds+for+environmental+modeling+from+molecular+structure&rft.au=Hilal%2C+SH%3BSaravanaraj%2C+AN%3BWhiteside%2C+T%3BCarreira%2C+LA&rft.aulast=Hilal&rft.aufirst=SH&rft.date=2007-12-01&rft.volume=21&rft.issue=12&rft.spage=693&rft.isbn=&rft.btitle=&rft.title=Journal+of+Computer-Aided+Molecular+Design&rft.issn=0920654X&rft_id=info:doi/10.1007%2Fs10822-007-9134-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Temperature effects; Protein kinase A; Solubility; Mathematical models; Algorithms; Solvents; Electrostatic properties; Computer applications; Light effects; Computer programs; Vapors; Pollutants; Boiling; Heat; Boundaries; Osteonectin; Diffusion coefficient; Organic compounds; Pressure; Structure-activity relationships; Ionization DO - http://dx.doi.org/10.1007/s10822-007-9134-y ER - TY - JOUR T1 - Analysis of air quality data near roadways using a dispersion model AN - 20667446; 8182830 AB - We used a dispersion model to analyze measurements made during a field study conducted by the U.S. EPA in July-August 2006, to estimate the impact of traffic emissions on air quality at distances of tens of meters from an eight-lane highway located in Raleigh, NC. The air quality measurements consisted of long path optical measurements of NO at distances of 7 and 17m from the edge of the highway. Sonic anemometers were used to measure wind speed and turbulent velocities at 6 and 20m from the highway. Traffic flow rates were monitored using traffic surveillance cameras. The dispersion model [Venkatram, A., 2004. On estimating emissions through horizontal fluxes. Atmospheric Environment 38, 2439-2446] explained over 60% of the variance of the observed path averaged NO concentrations, and over 90% of the observed concentrations were within a factor of two of the model estimates. Sensitivity tests conducted with the model indicated that the traffic flow rate made the largest contribution to the variance of the observed NO concentrations. The meteorological variable that had the largest impact on the near road NO concentrations was the standard deviation of the vertical velocity fluctuations, sigma sub(w). Wind speed had a relatively minor effect on concentrations. Furthermore, as long as the wind direction was within +/-45 super(o) from the normal to the road, wind direction had little impact on near road concentrations. The measurements did not allow us to draw conclusions on the impact of traffic-induced turbulence on dispersion. The analysis of air quality and meteorological observations resulted in plausible estimates of on-road emission factors for NO. JF - Atmospheric Environment AU - Venkatram, A AU - Isakov, V AU - Thoma, E AU - Baldauf, R AD - MD-E243-04, 109 T.N. Alexander Drive, Research Triangle Park, NC 27711, USA, Isakov.Vlad@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 9481 EP - 9497 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 40 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - Air quality KW - Measuring instruments KW - Flow rates KW - Wind speed KW - Emission measurements KW - Emissions KW - Meteorology KW - Vertical velocities KW - Meteorological observations KW - Sonic anemometers KW - Turbulence KW - Highways KW - Atmospheric pollution KW - Air quality measurements KW - Velocity KW - Wind direction KW - EPA KW - USA KW - traffic KW - Automotive exhaust emissions KW - Dispersion models KW - USA, North Carolina, Raleigh KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20667446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Analysis+of+air+quality+data+near+roadways+using+a+dispersion+model&rft.au=Venkatram%2C+A%3BIsakov%2C+V%3BThoma%2C+E%3BBaldauf%2C+R&rft.aulast=Venkatram&rft.aufirst=A&rft.date=2007-12-01&rft.volume=41&rft.issue=40&rft.spage=9481&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.08.045 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Wind speed; Air quality measurements; Atmospheric pollution models; Atmospheric pollution; Vertical velocities; Air quality; Sonic anemometers; Meteorological observations; Wind direction; Dispersion models; Velocity; Measuring instruments; Flow rates; EPA; traffic; Emissions; Emission measurements; Meteorology; Automotive exhaust emissions; Highways; Turbulence; USA; USA, North Carolina, Raleigh DO - http://dx.doi.org/10.1016/j.atmosenv.2007.08.045 ER - TY - JOUR T1 - The use of air quality forecasts to assess impacts of air pollution on crops: Methodology and case study AN - 20665754; 8182567 AB - It has been reported that ambient ozone (O sub(3)), either alone or in concurrence with acid rain precursors, accounts for up to 90% of US crop losses resulting from exposure to all major air pollutants. Crop damage due to O sub(3) exposure is of particular concern as ambient O sub(3) concentrations remain high in many major food-producing regions. Assessing O sub(3) damage to crops is challenging due to the difficulties in determining the reduction in crop yield that results from exposure to surface O sub(3), for which monitors are limited and mostly deployed in non-rural areas. This work explores the potential benefits of using operational air quality forecast (AQF) data to estimate rural O sub(3) exposure. Using the results from the first nationwide AQF as a case study, we demonstrate how the O sub(3) data provided by AQF can be combined with concurrent crop information to assess O sub(3) damages to soybeans in the United States. We estimate that exposure to ambient O sub(3) reduces the US soybean production by 10% in 2005. JF - Atmospheric Environment AU - Tong, D AU - Mathur, R AU - Schere, K AU - Kang, D AU - Yu, S AD - Air Resources Laboratory, National Oceanic and Atmospheric Administration, US EPA MD E243-03, Research Triangle Park, NC 27111, USA, tong.daniel@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 8772 EP - 8784 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 38 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - crop yield KW - Air quality KW - Crop damage KW - Crops KW - Ozone in troposphere KW - Ozone concentration KW - soybeans KW - Ozone KW - Acid rain KW - Atmospheric pollution KW - Crop yield KW - case studies KW - Air pollution KW - USA KW - Acid precipitation KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20665754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=The+use+of+air+quality+forecasts+to+assess+impacts+of+air+pollution+on+crops%3A+Methodology+and+case+study&rft.au=Tong%2C+D%3BMathur%2C+R%3BSchere%2C+K%3BKang%2C+D%3BYu%2C+S&rft.aulast=Tong&rft.aufirst=D&rft.date=2007-12-01&rft.volume=41&rft.issue=38&rft.spage=8772&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.07.060 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Ozone in troposphere; Atmospheric pollution; Acid precipitation; Crop yield; Ozone concentration; Air quality; Crop damage; Ozone; Air pollution; case studies; Acid rain; crop yield; soybeans; Crops; USA DO - http://dx.doi.org/10.1016/j.atmosenv.2007.07.060 ER - TY - JOUR T1 - Toxicoproteomics and its application to human health risk assessment AN - 20639086; 7955166 AB - Toxicoproteomics is the use of proteomic technologies to better understand environmental and genetic factors, toxic mechanisms, and modes of action in response to acute exposure to toxicants and in the long-term development of diseases caused or influenced by these exposures. Use of toxicoproteomic technologies to identify key biochemical pathways, mechanisms, and bio-markers of exposure and toxicity will decrease the uncertainties that are associated with human health risk assessments. This review provides an overview of toxicoproteomics from human health risk assessment perspectives. Key toxicoproteomic technologies such as 2-D gel-based proteomic methods and toxicoproteomic approaches are described, and examples of applications of these technologies and methodologies in the risk assessment context are presented. The discussion includes a focus on challenges and future directions. JF - Proteomics Clinical Applications AU - Ge, Y AU - Preston, R J AU - Owen, R D AD - Environmental Carcinogenesis Division, B 143-06, US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Research Triangle Park, NC 27711, USA, ge.yue@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 1613 EP - 1624 VL - 1 IS - 12 SN - 1862-8346, 1862-8346 KW - Toxicology Abstracts; Biotechnology and Bioengineering Abstracts KW - Risk assessment KW - Genetic factors KW - Toxicants KW - Reviews KW - proteomics KW - Toxicity KW - W 30900:Methods KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20639086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proteomics+Clinical+Applications&rft.atitle=Toxicoproteomics+and+its+application+to+human+health+risk+assessment&rft.au=Ge%2C+Y%3BPreston%2C+R+J%3BOwen%2C+R+D&rft.aulast=Ge&rft.aufirst=Y&rft.date=2007-12-01&rft.volume=1&rft.issue=12&rft.spage=1613&rft.isbn=&rft.btitle=&rft.title=Proteomics+Clinical+Applications&rft.issn=18628346&rft_id=info:doi/10.1002%2Fprca.200700490 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; Genetic factors; Toxicants; Reviews; Toxicity; proteomics DO - http://dx.doi.org/10.1002/prca.200700490 ER - TY - JOUR T1 - Concentration-dependent accumulation of [ super(3)H]-deltamethrin in sodium channel Na sub(v)1.2/ beta sub(1) expressing Xenopus laevis oocytes AN - 20556367; 7940751 AB - Disruption of neuronal voltage-sensitive sodium channels (VSSCs) by pyrethroid insecticides such as deltamethrin (DLT) has been widely studied using Xenopus laevis oocytes transfected with VSSC. However, the extent of pyrethroid accumulation in VSSC-expressing oocytes is unknown. Therefore, accumulation of [ super(3)H]-DLT in non-transfected, sham (water)-transfected and VSSC (Na sub(v)1.2+ beta sub(1))-transfected oocytes after a 1h exposure was measured using liquid scintillation counting. Successful transfection of Na sub(v)1.2+ beta sub(1) VSSCs in X. laevis oocytes was confirmed by two-electrode voltage-clamp; inward, tetrodotoxin (TTX)-sensitive currents were obtained in 98% of all oocytes examined (n=60 in nine experiments). DLT (1.0 mu M) induced tail currents in all VSSC-transfected oocytes; TTX also blocked these DLT-induced tail currents. In 0.1 mu M DLT solution, non-transfected oocytes accumulated 0.098+/-0.01ppm [ super(3)H]-DLT, sham-transfected oocytes accumulated 0.06+/-0.01ppm DLT, and VSSC-transfected oocytes accumulated 0.050+/-0.009ppm DLT. In 1.0 mu M DLT solution, non-transfected oocytes accumulated 0.62+/-0.08ppm DLT, sham-transfected oocytes accumulated 0.60+/-0.09ppm DLT, and VSSC-transfected oocytes accumulated 0.51+/-0.07ppm DLT. There was a significant difference in DLT accumulation between VSSC-transfected oocytes and non-transfected controls, where the transfected oocytes consistently had less accumulation. JF - Toxicology In Vitro AU - Watkins, JA AU - Meacham, CA AU - Crofton, K M AU - Shafer, T J AD - MD-B105-05, NHEERL, ORD, US Environmental Protection Agency, Research Triangle Park, NC 27711, United States, shafer.tim@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 1672 EP - 1677 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl] VL - 21 IS - 8 SN - 0887-2333, 0887-2333 KW - African clawed frog KW - Toxicology Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Sodium channels (voltage-gated) KW - Amphibiotic species KW - Toxicants KW - Pollution effects KW - Tetrodotoxin KW - Enumeration KW - Freshwater KW - Deltamethrin KW - Xenopus laevis KW - Bioaccumulation KW - Insecticides KW - Transfection KW - Scintillation KW - Oocytes KW - Pyrethroids KW - Ion exchange KW - Q5 08504:Effects on organisms KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20556367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+In+Vitro&rft.atitle=Concentration-dependent+accumulation+of+%5B+super%283%29H%5D-deltamethrin+in+sodium+channel+Na+sub%28v%291.2%2F+beta+sub%281%29+expressing+Xenopus+laevis+oocytes&rft.au=Watkins%2C+JA%3BMeacham%2C+CA%3BCrofton%2C+K+M%3BShafer%2C+T+J&rft.aulast=Watkins&rft.aufirst=JA&rft.date=2007-12-01&rft.volume=21&rft.issue=8&rft.spage=1672&rft.isbn=&rft.btitle=&rft.title=Toxicology+In+Vitro&rft.issn=08872333&rft_id=info:doi/10.1016%2Fj.tiv.2007.05.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Insecticides; Bioaccumulation; Toxicants; Amphibiotic species; Pollution effects; Oocytes; Tetrodotoxin; Ion exchange; Sodium channels (voltage-gated); Transfection; Scintillation; Enumeration; Pyrethroids; Deltamethrin; Xenopus laevis; Freshwater DO - http://dx.doi.org/10.1016/j.tiv.2007.05.002 ER - TY - JOUR T1 - Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-wall carbon nanotubes AN - 20535735; 8017929 AB - Many potential applications in nanotechnology envisage the use of better-dispersed and functionalized preparations of carbon nanotubes. Single-walled carbon nanotubes (SWCNTs) were treated with 1:1 mixtures of concentrated nitric and sulfuric acids for 3 min in a microwave oven under 20 psi pressure followed by extensive dialysis to remove the acids. This treatment resulted in acid functionalized SWCNTs (AF-SWCNTs) that had high negative charge (Zeta potential -40 to -60 mV) and were well dispersed (98% of the particles <150 nm) in aqueous suspensions. In vitro and in vivo toxic effects of SWCNTs and AF-SWCNTs were compared. AF-SWCNTs exerted a strong cytotoxic effect on LA4 mouse lung epithelial cells in culture that could be blocked by prior treatment of the nanotubes with poly L-lysine which neutralized the electric charge and promoted re-agglomeration. AF-SWCNT, but not the unmodified SWCNT preparations, strongly inhibited cell cycling of LA4 cells. Both SWCNTs and AF-SWCNTS were however equally effective in inducing apoptotic responses in LA4 cells as examined using an Annexin V binding assay. Oro-pharyngeal aspiration of AF-SWCNT preparation induced a strong acute inflammatory response in the lungs of CD1 mice, compared to control SWCNTs which caused only a marginal effect. Taken together the results indicate that unlike pristine SWCNTs, acid-functionalized SWCNT preparations exert strong toxic effects in vitro and in vivo and these effects can be reversed by neutralizing their surface charge. JF - Nanotoxicology AU - Saxena, Rajiv K AU - Williams, Wanda AU - McGee, John K AU - Daniels, Mary J AU - Boykin, Elizabeth AU - Gilmour, M Ian AD - Immunotoxicology Branch, ETD, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC, USA Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 291 EP - 300 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 1 IS - 4 SN - 1743-5390, 1743-5390 KW - Toxicology Abstracts KW - Epithelial cells KW - Dialysis KW - Apoptosis KW - Microwave oven KW - L-lysine KW - Cell culture KW - Toxicity KW - Surface charge KW - Inflammation KW - Cytotoxicity KW - Carbon KW - Lung KW - Zeta potential KW - Acids KW - Sulfuric acid KW - nanotubes KW - Pressure KW - Annexin V KW - nanotechnology KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20535735?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Enhanced+in+vitro+and+in+vivo+toxicity+of+poly-dispersed+acid-functionalized+single-wall+carbon+nanotubes&rft.au=Saxena%2C+Rajiv+K%3BWilliams%2C+Wanda%3BMcGee%2C+John+K%3BDaniels%2C+Mary+J%3BBoykin%2C+Elizabeth%3BGilmour%2C+M+Ian&rft.aulast=Saxena&rft.aufirst=Rajiv&rft.date=2007-12-01&rft.volume=1&rft.issue=4&rft.spage=291&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=17435390&rft_id=info:doi/10.1080%2F17435390701803110 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Epithelial cells; Dialysis; Apoptosis; Microwave oven; L-lysine; Cell culture; Surface charge; Toxicity; Inflammation; Cytotoxicity; Carbon; Lung; Acids; Zeta potential; Sulfuric acid; nanotubes; Pressure; Annexin V; nanotechnology DO - http://dx.doi.org/10.1080/17435390701803110 ER - TY - JOUR T1 - Testing impact attenuation on California playground surfaces made of recycled tires AN - 20523920; 8045241 AB - This study was conducted to determine whether rubberized playground surfaces made of recycled tires comply with state-mandated standards for impact attenuation (measured with an accelerometer), and whether their properties change in response to temperature or time. The Head Impact Criterion (HIC) standard of 1000 was found to be a more sensitive indicator of compliance than the G sub(max) standard of 200(g). Of 32 playgrounds tested, 22 (69 percent) failed the HIC standard. As the heights of playground structures increased, so did the likelihood that the rubberized surface below would fail the HIC standard. Rubberized surfaces gave stable readings for the first three months following installation, and higher values in response to increasing surface temperature. An excessively high percentage of playground surfaces made of recycled tires failed the state-mandated standards designed to prevent serious head injury from falls. Future failures might be prevented by requiring installers to perform post-installation testing to verify compliance. JF - International Journal of Injury Control and Safety Promotion AU - Vidair, C AU - Haas, R AU - Schlag, R AD - California Environmental Protection Agency, Office of Environmental Health Hazard Assessment, 1515 Clay Street, 16th Floor, Oakland, CA, USA 94612, cvidair@oehha.ca.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 225 EP - 230 VL - 14 IS - 4 SN - 1745-7300, 1745-7300 KW - Health & Safety Science Abstracts KW - Compliance KW - head injuries KW - accelerometers KW - Temperature KW - Impact analysis KW - Children KW - Recreation areas KW - Tires KW - USA, California KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20523920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Injury+Control+and+Safety+Promotion&rft.atitle=Testing+impact+attenuation+on+California+playground+surfaces+made+of+recycled+tires&rft.au=Vidair%2C+C%3BHaas%2C+R%3BSchlag%2C+R&rft.aulast=Vidair&rft.aufirst=C&rft.date=2007-12-01&rft.volume=14&rft.issue=4&rft.spage=225&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Injury+Control+and+Safety+Promotion&rft.issn=17457300&rft_id=info:doi/10.1080%2F17457300701584290 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - USA, California; Recreation areas; Tires; Compliance; Temperature; accelerometers; head injuries; Impact analysis; Children DO - http://dx.doi.org/10.1080/17457300701584290 ER - TY - JOUR T1 - Resident Attitudes toward Black Bears and Population Recovery in East Texas AN - 20491869; 8043236 AB - A successful species recovery relies on the support of local residents. Our goal was to assess attitudes toward black bears in a location where bears have not existed for several decades. We randomly surveyed East Texas residents to evaluate attitudes toward black bears and a potential bear population recovery. Positive attitudes toward bears were related to sex, age, participation in wildlife-related activities, residential tenure, land ownership, and knowledge about bears. However, substantial proportions of respondents indicated uncertainty regarding their attitudes about black bears and more than one-third of residents were unsure as to whether they supported increasing the local bear population. Lack of knowledge about black bears was the most commonly noted reason for uncertainty. These results suggest that opportunities exist for managers to address existing concerns about bears, assist residents with learning more about bears, and possibly help minimize potential for bear-human conflict. JF - Human Dimensions of Wildlife AU - Morzillo, A T AU - Mertig, A G AU - Garner, N AU - Liu, J AD - Center for Systems Integration and Sustainability, Department of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan, USA, morzillo.anita@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 417 EP - 428 VL - 12 IS - 6 SN - 1087-1209, 1087-1209 KW - Sustainability Science Abstracts KW - conflicts KW - Age KW - Wildlife KW - land ownership KW - attitudes KW - bears KW - USA, Texas KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20491869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+Dimensions+of+Wildlife&rft.atitle=Resident+Attitudes+toward+Black+Bears+and+Population+Recovery+in+East+Texas&rft.au=Morzillo%2C+A+T%3BMertig%2C+A+G%3BGarner%2C+N%3BLiu%2C+J&rft.aulast=Morzillo&rft.aufirst=A&rft.date=2007-12-01&rft.volume=12&rft.issue=6&rft.spage=417&rft.isbn=&rft.btitle=&rft.title=Human+Dimensions+of+Wildlife&rft.issn=10871209&rft_id=info:doi/10.1080%2F10871200701670110 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - USA, Texas; bears; attitudes; conflicts; Wildlife; land ownership; Age DO - http://dx.doi.org/10.1080/10871200701670110 ER - TY - JOUR T1 - A Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Carbofuran in Sprague-Dawley Rats Using the Exposure-Related Dose Estimating Model AN - 20401583; 7746656 AB - Carbofuran (2,3-dihydro-2,2-dimethyl-7-benzofuranyl-N-methylcarbamate), a broad spectrum N-methyl carbamate insecticide, and its metabolite, 3-hydroxycarbofuran, exert their toxicity by reversibly inhibiting acetylcholinesterase (AChE). To characterize AChE inhibition from carbofuran exposure, a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model was developed in the Exposure-Related Dose Estimating Model (ERDEM) platform for the Sprague-Dawley (SD) rat. Experimental estimates of physiological, biochemical, and physicochemical model parameters were obtained or based on data from the open literature. The PBPK/PD model structure included carbofuran metabolism in the liver to 16 known metabolites, enterohepatic circulation of glucuronic acid conjugates, and excretion in urine and feces. Bolus doses by ingestion of 50 mu g/kg and 0.5 mg/kg carbofuran were simulated for the blood and brain AChE activity. The carbofuran ERDEM simulated a half-life of 5.2 h for urinary clearance, and the experimental AChE activity data were reproduced for the blood and brain. Thirty model parameters were found influential to the model outputs and were chosen for perturbation in Monte Carlo simulations to evaluate the impact of their variability on the model predictions. Results of the simulation runs indicated that the minimum AChE activity in the blood ranged from 29.3 to 79.0% (as 5th and 95th percentiles) of the control level with a mean of 55.9% (standard deviation = 15.1%) compared to an experimental value of 63%. The constructed PBPK/PD model for carbofuran in the SD rat provides a foundation for extrapolating to a human model that can be used for future risk assessment. JF - Toxicological Sciences AU - Zhang, Xiaofei AU - Tsang, Andy M AU - Okino, Miles S AU - Power, Frederick W AU - Knaak, James B AU - Harrison, Lynda S AU - Dary, Curtis C AD - General Dynamics Information Technology, Henderson, Nevada 89074. National Exposure Research Laboratory, U.S. Environmental Protection Agency (EPA), Las Vegas, Nevada 89193. Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York 14214 Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 345 EP - 359 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 100 IS - 2 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Monte Carlo simulation KW - Risk assessment KW - Carbofuran KW - Acetylcholinesterase KW - Parkinson's disease KW - Brain KW - Animal models KW - Metabolites KW - Toxicity KW - Pesticides (carbamates) KW - Pharmacokinetics KW - Models KW - Blood KW - Neurodegenerative diseases KW - Insecticides KW - Movement disorders KW - Standard deviation KW - Urine KW - Liver KW - Excretion KW - Feces KW - Pharmacodynamics KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20401583?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=A+Physiologically+Based+Pharmacokinetic%2FPharmacodynamic+Model+for+Carbofuran+in+Sprague-Dawley+Rats+Using+the+Exposure-Related+Dose+Estimating+Model&rft.au=Zhang%2C+Xiaofei%3BTsang%2C+Andy+M%3BOkino%2C+Miles+S%3BPower%2C+Frederick+W%3BKnaak%2C+James+B%3BHarrison%2C+Lynda+S%3BDary%2C+Curtis+C&rft.aulast=Zhang&rft.aufirst=Xiaofei&rft.date=2007-12-01&rft.volume=100&rft.issue=2&rft.spage=345&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Monte Carlo simulation; Carbofuran; Acetylcholinesterase; Parkinson's disease; Animal models; Brain; Metabolites; Toxicity; Pesticides (carbamates); Pharmacokinetics; Models; Neurodegenerative diseases; Blood; Standard deviation; Movement disorders; Insecticides; Urine; Liver; Excretion; Feces; Pharmacodynamics ER - TY - JOUR T1 - Contribution of Allochthonous Carbon to American Shad Production in the Mattaponi River, Virginia, Using Stable Isotopes AN - 19892776; 8027319 AB - Our objective was to quantify the contribution of autochthonous, locally- produced phytoplankton, and allochthonous, terrestrial-derived organic matter (OM) to the production of young-of-year (YOY) American shad (Alosa sapidissima) using stable isotopes. We measured the carbon and nitrogen stable isotope composition of YOY American shad in the tidal fresh water of the Mattaponi River, a tributary in the York River estuary, during three consecutive years. The isotopic ratios of larval American shad varied among years, indicating a switch from reliance on a primarily autochthonous food web pathway during low and moderate discharge years (50-90%; 2002, 2004) to a primarily allochthonous pathway during a high discharge year (< 35% phytoplankton; 2003). Reliance on phytoplankton by larval fish declined exponentially with increasing Mattaponi River discharge. In 2003, juvenile production was also supported by allochthonous OM, though autochthonous phytoplankton accounted for an increasingly large fraction during June through August, up to 40-55%. We also found a long-term, positive relationship between the duration of above average flow during April through June in the Mattaponi River and a corresponding index of juvenile American shad abundance. The largest American shad cohort recorded since 1967 was observed in 2003, a high discharge year. The production of this cohort was largely supported by allochthonous OM. The results suggest an important link between river discharge, energy flow, and recruitment, wherein high discharge favors reliance on terrestrial carbon by YOY American shad, owing to changes in zooplankton diet, macroinvertebrate abundance, or both, and also favors high American shad abundance. JF - Estuaries and Coasts AU - Hoffman, Joel C AU - Bronk, Deborah A AU - Olney, John E AD - Virginia Institute of Marine Science, Post Office Box 1346, Gloucester Point, Virginia 23062, Hoffman.Joel@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 1034 EP - 1048 PB - Estuarine Research Federation, 490 Chippingwood Dr. No. 2 Port Republic MD 20676-2140 USA VL - 30 IS - 6 SN - 1559-2723, 1559-2723 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Isotopes KW - Abundance KW - Phytoplankton KW - Freshwater KW - Primary production KW - ANW, USA, Virginia KW - Carbon KW - Alosa sapidissima KW - USA, Virginia, Mattaponi R. KW - Tributaries KW - Food webs KW - Coasts KW - Rivers KW - Freshwater environments KW - Organic matter KW - Estuaries KW - Zooplankton KW - Recruitment KW - River discharge KW - USA, Virginia, York R. KW - Energy flow KW - Depleted stocks KW - Introduced species KW - Nitrogen KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08442:Population dynamics KW - K 03450:Ecology KW - O 5020:Fisheries and Fishery Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19892776?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuaries+and+Coasts&rft.atitle=Contribution+of+Allochthonous+Carbon+to+American+Shad+Production+in+the+Mattaponi+River%2C+Virginia%2C+Using+Stable+Isotopes&rft.au=Hoffman%2C+Joel+C%3BBronk%2C+Deborah+A%3BOlney%2C+John+E&rft.aulast=Hoffman&rft.aufirst=Joel&rft.date=2007-12-01&rft.volume=30&rft.issue=6&rft.spage=1034&rft.isbn=&rft.btitle=&rft.title=Estuaries+and+Coasts&rft.issn=15592723&rft_id=info:doi/10.1043%2F1559-2723%282007%29302.0.CO%3B2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-03-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Carbon; Organic matter; Recruitment; Depleted stocks; River discharge; Phytoplankton; Introduced species; Tributaries; Primary production; Rivers; Isotopes; Freshwater environments; Zooplankton; Abundance; Estuaries; Energy flow; Food webs; Coasts; Nitrogen; Alosa sapidissima; USA, Virginia, Mattaponi R.; USA, Virginia, York R.; ANW, USA, Virginia; Freshwater DO - http://dx.doi.org/10.1043/1559-2723(2007)30[1034:COACTA]2.0.CO;2 ER - TY - JOUR T1 - Effect of sampling method on diatom composition for use in monitoring and assessing large river condition AN - 19642702; 8235849 AB - Multiple diatom sampling methods exist for the assessment of lotic systems but few comparisons of their application efficacies in monitoring have been conducted. In this study 60 sites were sampled on four large, non-wadeable rivers in Ohio and Kentucky, USA, which varied in depth, flow rate, surrounding land use and hydrologic modification. Four algae sampling methods were tested: three methods U.S. Environmental Protection Agency (U.S. EPA) Environmental Monitoring and Assessment Program (EMAP), U.S. Geological Survey (USGS QUAL and USGS QUAN) collected algae from rocks, debris and sediment in the littoral zone along a 1-2km reach, while one method (USGS PHYTO) consisted of three cross-river phytoplankton grab samples collected from a boat. Physical and chemical data were also collected. Little difference in diatom assemblage composition was found among the EMAP, QUAL and QUAN methods. Although compositionally similar, the PHYTO method collected a substantial proportion of relatively unique diatoms compared to the littoral zone methods. Two disturbance gradients were calculated, one based on 1km upstream land use within a 500m buffer, and the other based on principal component analysis dimension reduction of measured water parameters (PCAWQ). Metrics, generally indicators of eutrophication, were calculated for each sampling method and correlated with the disturbance gradients. After Bonferroni corrections, the EMAP method had six metrics correlated with the PCAWQ, while the PHYTO and QUAL methods each had four correlated metrics. Two QUAN metrics were correlated with the PCAWQ. Few metrics were correlated with the land use measure of disturbance. While the EMAP method had the most correlated metrics, this method, along with QUAL and QUAN methods are time and labour intensive (>1h), relative to the phytoplankton method (<20min). Resource managers may desire to weigh the benefits of two additional metrics with the EMAP method versus the costs associated with increased sampling time and effort. Published in 2007 by John Wiley & Sons, Ltd. JF - River Research and Applications AU - Lane, Charles R AU - Flotemersch, Joseph E AU - Blocksom, Karen A AU - Decelles, Susanna AD - U.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, 26 W Martin Luther King Dr. MS-642, Cincinnati, Ohio 45268, USA, lane.charles@epa.gov Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 1126 EP - 1146 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk] VL - 23 IS - 10 SN - 1535-1459, 1535-1459 KW - Aqualine Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts; Pollution Abstracts; ASFA 1: Biological Sciences & Living Resources; Water Resources Abstracts KW - Land Use KW - Phyto KW - buffers KW - Bacillariophyceae KW - Phytoplankton KW - Freshwater KW - Primary production KW - Algae KW - Environmental monitoring KW - Rivers KW - disturbance KW - principal components analysis KW - River discharge KW - Land use KW - EPA KW - USA, Kentucky KW - Principal components analysis KW - Periphyton KW - Monitoring KW - Eutrophication KW - geological surveys KW - Diatoms KW - Flow rates KW - upstream KW - Boats KW - Assessments KW - Littoral Zone KW - Sampling KW - Littoral zone KW - Sediment pollution KW - Plankton surveys KW - Data processing KW - boats KW - Grabs KW - Sediments KW - USA, Ohio KW - Sampling methods KW - D 04070:Pollution KW - P 2000:FRESHWATER POLLUTION KW - SW 0835:Streamflow and runoff KW - K 03450:Ecology KW - Q1 08481:Productivity KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19642702?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=River+Research+and+Applications&rft.atitle=Effect+of+sampling+method+on+diatom+composition+for+use+in+monitoring+and+assessing+large+river+condition&rft.au=Lane%2C+Charles+R%3BFlotemersch%2C+Joseph+E%3BBlocksom%2C+Karen+A%3BDecelles%2C+Susanna&rft.aulast=Lane&rft.aufirst=Charles&rft.date=2007-12-01&rft.volume=23&rft.issue=10&rft.spage=1126&rft.isbn=&rft.btitle=&rft.title=River+Research+and+Applications&rft.issn=15351459&rft_id=info:doi/10.1002%2Frra.1038 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Rivers; Environmental monitoring; Plankton surveys; Eutrophication; Grabs; River discharge; Phytoplankton; Periphyton; Primary production; Data processing; Diatoms; Land use; Sediments; Boats; Principal components analysis; Sampling; Algae; Littoral zone; Sediment pollution; disturbance; principal components analysis; buffers; boats; geological surveys; Flow rates; EPA; upstream; Sampling methods; Land Use; Littoral Zone; Assessments; Monitoring; Phyto; Bacillariophyceae; USA, Kentucky; USA, Ohio; Freshwater DO - http://dx.doi.org/10.1002/rra.1038 ER - TY - JOUR T1 - Panel discussion review: session three -- issues involved in interpretation of epidemiologic analyses -- statistical modeling AN - 19566379; 8831608 AB - The Clean Air Act mandates that the US Environmental Protection Agency (EPA) develop National Ambient Air Quality Standards for criteria air pollutants and conduct periodic reviews of the standards based on new scientific evidence. In recent reviews, evidence from epidemiologic studies has played a key role. Epidemiologic studies often provide evidence for effects of several air pollutants. Determining whether there are independent effects of the separate pollutants is a challenge. Among the many issues confronting the interpretation of epidemiologic studies of multi-pollutant exposures and health effects are those specifically related to statistical modeling. The EPA convened a workshop on 13 and 14 December 2006 in Chapel Hill, North Carolina, USA, to discuss these and other issues; Session Three of the workshop was devoted specifically to statistical modeling. Prominent statistical modeling issues in epidemiologic studies of air pollution include (1) measurement error across the co-pollutants; (2) correlation and multi-collinearity among the co-pollutants; (3) the timing of the concentration-response function; (4) confounding; and (5) spatial analyses. The views expressed in this paper are those of the authors and do not necessarily reflect the views of policies of the US Environmental Protection Agency. JF - Journal of Exposure Science and Environmental Epidemiology AU - Bateson, T F AU - Coull, BA AU - Hubbell, B AU - Ito, K AU - Jerrett, M AU - Lumley, T AU - Thomas, D AU - Vedal, S AU - Ross, M AD - US Environmental Protection Agency, 1200 Pennsylvania Avenue, NW, Mail Code 8623D, Washington, District of Columbia 20460, USA, bateson.thomas@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - S90 EP - S96 VL - 17 SN - 1559-0631, 1559-0631 KW - Pollution Abstracts KW - spatial analysis KW - USA, North Carolina KW - Air pollution KW - Air quality standards KW - Clean Air Act KW - EPA KW - Reviews KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19566379?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.atitle=Panel+discussion+review%3A+session+three+--+issues+involved+in+interpretation+of+epidemiologic+analyses+--+statistical+modeling&rft.au=Bateson%2C+T+F%3BCoull%2C+BA%3BHubbell%2C+B%3BIto%2C+K%3BJerrett%2C+M%3BLumley%2C+T%3BThomas%2C+D%3BVedal%2C+S%3BRoss%2C+M&rft.aulast=Bateson&rft.aufirst=T&rft.date=2007-12-01&rft.volume=17&rft.issue=&rft.spage=S90&rft.isbn=&rft.btitle=&rft.title=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.issn=15590631&rft_id=info:doi/10.1038%2Fsj.jes.7500631 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Clean Air Act; spatial analysis; Air quality standards; Air pollution; EPA; Reviews; USA, North Carolina DO - http://dx.doi.org/10.1038/sj.jes.7500631 ER - TY - JOUR T1 - Panel discussion review: session four -- assessing biological plausibility of epidemiological findings in air pollution research AN - 19564931; 8831609 AB - In December 2006, the U.S. Environmental Protection Agency (EPA) sponsored a 2-day workshop on "Interpretation of Epidemiologic Studies of Multipollutant Exposure and Health Effects" in Chapel Hill, NC. The final session at this workshop was devoted to assessing the biological plausibility of epidemiological findings with regard to criteria air pollutants. The presentations and the panel contributions of this last session primarily focused on controlled exposure studies and led to wide-ranging discussions, some of which were provocative. The panel summary provides some guidance to future evaluations of the biological plausibility of the epidemiological reports on criteria pollutants and is intended to stimulate thinking, without drawing any definitive conclusions. This paper does not approach, nor was it intended to approach, the more formal analytical approach such as that used in EPA's development of its Science Assessment Document for the criteria pollutants. JF - Journal of Exposure Science and Environmental Epidemiology AU - Brown, J S AU - Graham, JA AU - Chen, L C AU - Postlethwait, E M AU - Ghio, A J AU - Foster, WM AU - Gordon, T AD - U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, B243-01, Research Triangle Park, NC 27711, USA, Brown.James@epa.gov Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - S97 EP - S105 VL - 17 SN - 1559-0631, 1559-0631 KW - Pollution Abstracts KW - Air pollution KW - EPA KW - USA KW - Reviews KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19564931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.atitle=Panel+discussion+review%3A+session+four+--+assessing+biological+plausibility+of+epidemiological+findings+in+air+pollution+research&rft.au=Brown%2C+J+S%3BGraham%2C+JA%3BChen%2C+L+C%3BPostlethwait%2C+E+M%3BGhio%2C+A+J%3BFoster%2C+WM%3BGordon%2C+T&rft.aulast=Brown&rft.aufirst=J&rft.date=2007-12-01&rft.volume=17&rft.issue=&rft.spage=S97&rft.isbn=&rft.btitle=&rft.title=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.issn=15590631&rft_id=info:doi/10.1038%2Fsj.jes.7500632 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Air pollution; EPA; Reviews; USA DO - http://dx.doi.org/10.1038/sj.jes.7500632 ER - TY - JOUR T1 - Identification of Compounds in Water Above a Pollutant Plume by High-Resolution Mass Spectrometry AN - 19551459; 8681356 AB - Identification of compounds in contaminated media is essential for determining sources of pollution and for assessing risks posed by the chemicals to ecosystems or human health. Eighty-five compounds were identified or tentatively identified in a 1-L extract of water sampled above a pollutant plume containing wastes from a chemical plant. Gas chromatography/high-resolution mass spectrometry determined exact masses of apparent molecular ions and the exact masses and RIAs (relative isotopic abundances) of their +1 and +2 isotopic mass peaks, which provided their elemental compositions. Ion compositions, mass spectral libraries, the presence of related compounds, and knowledge of organic chemistry provided tentative identifications, half of which were confirmed by comparison of analyte retention times and mass spectra with those of standards. JF - Environmental Forensics AU - Grange, Andrew H AU - Sovocool, G Wayne AD - United States Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Environmental Sciences Division, Las Vegas, NV Y1 - 2007/12// PY - 2007 DA - Dec 2007 SP - 391 EP - 404 PB - Taylor & Francis, 11 New Fetter Lane London EC4P 4EE UK, [mailto:info@tandf.co.uk], [URL:http://www.tandf.co.uk] VL - 8 IS - 4 SN - 1527-5922, 1527-5922 KW - Pollution Abstracts; Water Resources Abstracts; Meteorological & Geoastrophysical Abstracts KW - Chemicals KW - Mass Spectrometry KW - Water sampling KW - Ecosystems KW - Environmental health KW - Mass spectrometry KW - Public health KW - Pollutants KW - Mass Spectra KW - Chemical Wastes KW - Gas chromatography KW - Meteorological literature KW - Plumes KW - Ions KW - Chemical composition KW - Retention Time KW - Analytical Methods KW - Standards KW - Chemical plants KW - P 2000:FRESHWATER POLLUTION KW - SW 3020:Sources and fate of pollution KW - M2 551.508:Instruments (551.508) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19551459?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Forensics&rft.atitle=Identification+of+Compounds+in+Water+Above+a+Pollutant+Plume+by+High-Resolution+Mass+Spectrometry&rft.au=Grange%2C+Andrew+H%3BSovocool%2C+G+Wayne&rft.aulast=Grange&rft.aufirst=Andrew&rft.date=2007-12-01&rft.volume=8&rft.issue=4&rft.spage=391&rft.isbn=&rft.btitle=&rft.title=Environmental+Forensics&rft.issn=15275922&rft_id=info:doi/10.1080%2F15275920701729340 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Ecosystems; Gas chromatography; Meteorological literature; Mass spectrometry; Chemicals; Ions; Chemical composition; Water sampling; Environmental health; Chemical plants; Plumes; Public health; Mass Spectrometry; Mass Spectra; Pollutants; Analytical Methods; Chemical Wastes; Retention Time; Standards DO - http://dx.doi.org/10.1080/15275920701729340 ER - TY - JOUR T1 - Valuing acid mine drainage remediation in West Virginia: benefit transfer with preference calibration AN - 1611620040; 20789712 AB - Several thousand kilometers of West Virginia streams are degraded by acid mine drainage, and the estimates for cleanup range in the billions of dollars (US$). This article demonstrates the use of a nonmarket valuation technique, benefit transfer, to estimate the benefits of restoring an impaired region of the Cheat River Watershed in West Virginia. Second, we compare two benefit transfer tools that can be used for making decisions about restoration under constrained budgets. We find the annual value of remediation in a two-county region to be between $1.4 and $8.9 million, depending on the estimating model. The results from our research demonstrate the challenges involved in applying benefit transfer to a policy site, as well as the differences in outcome between a simple unit transfer technique and a new preference calibration benefit transfer technique. JF - Environmental Economics and Policy Studies AU - Williamson, James M AU - Thurston, Hale W AU - Heberling, Matthew T AD - United States Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, 26 W, Martin Luther King Drive, Cincinnati, OH, 45268, USA Y1 - 2007/12// PY - 2007 DA - December 2007 SP - 271 EP - 293 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 8 IS - 4 SN - 1432-847X, 1432-847X KW - Pollution Abstracts; Sustainability Science Abstracts; Environment Abstracts KW - Bioremediation KW - Acidic wastes KW - Environmental economics KW - Budgets KW - Watersheds KW - USA, West Virginia KW - Streams KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611620040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Economics+and+Policy+Studies&rft.atitle=Valuing+acid+mine+drainage+remediation+in+West+Virginia%3A+benefit+transfer+with+preference+calibration&rft.au=Williamson%2C+James+M%3BThurston%2C+Hale+W%3BHeberling%2C+Matthew+T&rft.aulast=Williamson&rft.aufirst=James&rft.date=2007-12-01&rft.volume=8&rft.issue=4&rft.spage=271&rft.isbn=&rft.btitle=&rft.title=Environmental+Economics+and+Policy+Studies&rft.issn=1432847X&rft_id=info:doi/10.1007%2FBF03353961 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Number of references - 44 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Acidic wastes; Bioremediation; Environmental economics; Budgets; Watersheds; Streams; USA, West Virginia DO - http://dx.doi.org/10.1007/BF03353961 ER - TY - JOUR T1 - Folate deficiency enhances arsenic effects on expression of genes involved in epidermal differentiation in transgenic K6/ODC mouse skin AN - 19524020; 8181846 AB - Chronic arsenic exposure in humans is associated with cancers of the skin, lung, bladder and other tissues. There is evidence that folate deficiency may increase susceptibility to arsenic effects, including skin lesions. K6/ODC mice develop skin tumors when exposed to 10ppm sodium arsenite for 5 months. In the current study, K6/ODC mice maintained on either a folate deficient or folate sufficient diet were exposed to 0, 1, or 10ppm sodium arsenite in the drinking water for 30 days. Total RNA was isolated from skin samples and gene expression analyzed using Affymetrix Mouse 430 2.0 GeneChips. Data from 24 samples, with 4 mice in each of the 6 treatment groups, were RMA normalized and analyzed by two-way ANOVA using GeneSpring(TM). Top gene ontology (GO) categories for genes responding significantly to both arsenic treatment and folate deficiency include nucleotide metabolism and cell organization and biogenesis. For many of these genes, folate deficiency magnifies the response to arsenic treatment. In particular, expression of markers of epidermal differentiation, e.g., loricrin, small proline rich proteins and involucrin, was significantly reduced by arsenic in the folate sufficient animals, and reduced further or at a lower arsenic dose in the folate deficient animals. In addition, expression of a number of epidermal cell growth/proliferation genes and cellular movement genes was altered. These results indicate that arsenic disrupts the normal balance of cell proliferation and differentiation, and that folate deficiency exacerbates these effects, consistent with the view that folate deficiency is a nutritional susceptibility factor for arsenic-induced skin tumorigenesis. JF - Toxicology AU - Nelson, G M AU - Ahlborn, G J AU - Delker, DA AU - Kitchin, K T AU - O'Brien, T G AU - Chen, Y AU - Kohan, MJ AU - Roop, B C AU - Ward, W O AU - Allen, J W AD - Research Triangle Park, NC, United States, allen.james@epa.gov Y1 - 2007/11/30/ PY - 2007 DA - 2007 Nov 30 SP - 134 EP - 145 PB - Elsevier Science, P.O. Box 85 Limerick Ireland VL - 241 IS - 3 SN - 0300-483X, 0300-483X KW - Genetics Abstracts; Biotechnology and Bioengineering Abstracts; Toxicology Abstracts KW - Diets KW - Proline KW - Arsenic KW - Sodium arsenite KW - Data processing KW - Urinary bladder KW - Tumorigenesis KW - Ornithine decarboxylase KW - Cancer KW - Nucleotides KW - Differentiation KW - RNA KW - Skin diseases KW - Lung KW - Risk factors KW - Cell proliferation KW - Drinking water KW - Folic acid KW - Metabolism KW - W 30925:Genetic Engineering KW - X 24360:Metals KW - G 07730:Development & Cell Cycle UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19524020?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Folate+deficiency+enhances+arsenic+effects+on+expression+of+genes+involved+in+epidermal+differentiation+in+transgenic+K6%2FODC+mouse+skin&rft.au=Nelson%2C+G+M%3BAhlborn%2C+G+J%3BDelker%2C+DA%3BKitchin%2C+K+T%3BO%27Brien%2C+T+G%3BChen%2C+Y%3BKohan%2C+MJ%3BRoop%2C+B+C%3BWard%2C+W+O%3BAllen%2C+J+W&rft.aulast=Nelson&rft.aufirst=G&rft.date=2007-11-30&rft.volume=241&rft.issue=3&rft.spage=134&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2007.08.094 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Diets; Arsenic; Proline; Data processing; Sodium arsenite; Urinary bladder; Tumorigenesis; Ornithine decarboxylase; Nucleotides; Cancer; Differentiation; Skin diseases; RNA; Lung; Risk factors; Folic acid; Drinking water; Cell proliferation; Metabolism DO - http://dx.doi.org/10.1016/j.tox.2007.08.094 ER - TY - JOUR T1 - NMR analysis of male fathead minnow urinary metabolites: A potential approach for studying impacts of chemical exposures AN - 19294468; 7735072 AB - The potential for profiling metabolites in urine from male fathead minnows (Pimephales promelas) to assess chemical exposures was explored using nuclear magnetic resonance (NMR) spectroscopy. Both one-dimensional (1D) and two-dimensional (2D) NMR spectroscopy was used for the assignment of metabolites in urine from unexposed fish. Because fathead minnow urine is dilute, we lyophilized these samples prior to analysis. Furthermore, 1D super(1)H NMR spectra of unlyophilized urine from unexposed male fathead minnow and Sprague-Dawley rat were acquired to qualitatively compare rat and fish metabolite profiles and to provide an estimate of the total urinary metabolite pool concentration difference. As a small proof-of-concept study, lyophilized urine samples from male fathead minnows exposed to three different concentrations of the antiandrogen vinclozolin were analyzed by 1D super(1)H NMR to assess exposure-induced changes. Through a combination of principal components analysis (PCA) and measurements of super(1)H NMR peak intensities, several metabolites were identified as changing with statistical significance in response to exposure. Among those changes occurring in response to exposure to the highest concentration (450 mu g/L) of vinclozolin were large increases in taurine, lactate, acetate, and formate. These increases coincided with a marked decrease in hippurate, a combination potentially indicative of hepatotoxicity. The results of these investigations clearly demonstrate the potential utility of an NMR-based approach for assessing chemical exposures in male fathead minnow, using urine collected from individual fish. JF - Aquatic Toxicology AU - Ekman AU - Teng, Q AU - Jensen, K M AU - Martinovic, D AU - Villeneuve, D L AU - Ankley, G T AU - Collette, T W AD - U.S. EPA, 960 College Station Road, Athens, GA 30605, United States, ekman.drew@epa.gov Y1 - 2007/11/30/ PY - 2007 DA - 2007 Nov 30 SP - 104 EP - 112 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 85 IS - 2 SN - 0166-445X, 0166-445X KW - Toxicology Abstracts; Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Statistics KW - Males KW - Principal Component Analysis KW - Metabolites KW - Spectroscopy KW - Freshwater fish KW - Utilities KW - Exposure KW - Magnetic resonance spectroscopy KW - N.M.R. KW - NMR KW - Chemical pollution KW - Toxicology KW - Bioindicators KW - principal components analysis KW - Vinclozolin KW - Lactate KW - Profiling KW - Fathead Minnows KW - Acetic acid KW - hepatotoxicity KW - Taurine KW - Pimephales promelas KW - antiandrogens KW - Profiles KW - Urine KW - Principal components analysis KW - Acetate KW - Lactic acid KW - Fish KW - Nuclear magnetic resonance KW - Q5 08503:Characteristics, behavior and fate KW - SW 3030:Effects of pollution KW - AQ 00003:Monitoring and Analysis of Water and Wastes KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19294468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Toxicology&rft.atitle=NMR+analysis+of+male+fathead+minnow+urinary+metabolites%3A+A+potential+approach+for+studying+impacts+of+chemical+exposures&rft.au=Ekman%3BTeng%2C+Q%3BJensen%2C+K+M%3BMartinovic%2C+D%3BVilleneuve%2C+D+L%3BAnkley%2C+G+T%3BCollette%2C+T+W&rft.aulast=Ekman&rft.aufirst=&rft.date=2007-11-30&rft.volume=85&rft.issue=2&rft.spage=104&rft.isbn=&rft.btitle=&rft.title=Aquatic+Toxicology&rft.issn=0166445X&rft_id=info:doi/10.1016%2Fj.aquatox.2007.08.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Urine; Lactate; Males; Acetate; Profiling; Nuclear magnetic resonance; Freshwater fish; Toxicology; Taurine; antiandrogens; Statistics; Vinclozolin; Principal components analysis; Magnetic resonance spectroscopy; Lactic acid; N.M.R.; Metabolites; Acetic acid; hepatotoxicity; Bioindicators; principal components analysis; Chemical pollution; NMR; Spectroscopy; Profiles; Exposure; Principal Component Analysis; Fish; Fathead Minnows; Utilities; Pimephales promelas DO - http://dx.doi.org/10.1016/j.aquatox.2007.08.005 ER - TY - JOUR T1 - Estimating 3-dimensional colony surface area of field corals AN - 20496633; 7637003 AB - Colony surface area is a critical descriptor for biological and physical attributes of reef-building (scleractinian, stony) corals. The three-dimensional (3D) size and structure of corals are directly related to many ecosystem values and functions. Most methods to estimate colony surface area have been limited to laboratory settings and cannot be used for field corals. Photographic methods for digital 3D reconstruction were applied here to determine the accuracy of three different approaches for estimating colony surface area of field corals from simple underwater measurements. The approaches include a volumetric size-class method, a hemispherical surrogate and a suite of log-linear models generated from stepwise multiple regression analyses of digitally-reconstructed colonies. For each approach, surface area values were calculated from field measurements of colony size and the accuracy was determined by comparison with digitally-derived values for the same colonies. Accuracy varied among approaches; log-linear models (12% difference) were most accurate, followed by the hemispherical surrogate (17% difference) and size-classes (40% difference). The log-linear and hemispherical surrogate approaches are potentially applicable to at least nine common coral species. The photographic reconstruction method, although time-consuming and not intended for routine application, was shown by comparison with laser-scanned images to provide a highly accurate method for determining 3D colony surface area. JF - Journal of Experimental Marine Biology and Ecology AU - Courtney, LA AU - Fisher, W S AU - Raimondo, S AU - Oliver, L M AU - Davis, W P AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, FL 32561, USA, courtney.lee@epa.gov Y1 - 2007/11/23/ PY - 2007 DA - 2007 Nov 23 SP - 234 EP - 242 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 351 IS - 1-2 SN - 0022-0981, 0022-0981 KW - ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; Ecology Abstracts KW - Scleractinia KW - Marine KW - Colonies KW - Surface area KW - Coral reefs KW - Area KW - Regression analysis KW - Multiple regression analysis KW - Corals KW - Models KW - O 1070:Ecology/Community Studies KW - Q1 08245:Genetics and evolution KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20496633?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.atitle=Estimating+3-dimensional+colony+surface+area+of+field+corals&rft.au=Courtney%2C+LA%3BFisher%2C+W+S%3BRaimondo%2C+S%3BOliver%2C+L+M%3BDavis%2C+W+P&rft.aulast=Courtney&rft.aufirst=LA&rft.date=2007-11-23&rft.volume=351&rft.issue=1-2&rft.spage=234&rft.isbn=&rft.btitle=&rft.title=Journal+of+Experimental+Marine+Biology+and+Ecology&rft.issn=00220981&rft_id=info:doi/10.1016%2Fj.jembe.2007.06.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-11-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Coral reefs; Area; Colonies; Surface area; Regression analysis; Multiple regression analysis; Corals; Models; Scleractinia; Marine DO - http://dx.doi.org/10.1016/j.jembe.2007.06.021 ER - TY - JOUR T1 - New and evolving concepts in the neurotoxicology of lead AN - 20418819; 7786515 AB - Lead (Pb) is a xenobiotic metal with no known essential function in cellular growth, proliferation, or signaling. Decades of research characterizing the toxicology of Pb have shown it to be a potent neurotoxicant, especially during nervous system development. New concepts in the neurotoxicology of Pb include advances in understanding the mechanisms and cellular specificity of Pb. Experimental studies have shown that stress can significantly alter the effects of Pb, effects that could potentially be mediated through alterations in the interactions of glucocorticoids with the mesocorticolimbic dopamine system of the brain. Elevated stress, with corresponding elevated glucocorticoid levels, has been postulated to contribute to the increased levels of many diseases and dysfunctions in low socioeconomic status populations. Cellular models of learning and memory have been utilized to investigate the potential mechanisms of Pb-induced cognitive deficits. Examination of long-term potentiation in the rodent hippocampus has revealed Pb-induced increases in threshold, decreases in magnitude, and shorter retention times of synaptic plasticity. Structural plasticity in the form of adult neurogenesis in the hippocampus is also impacted by Pb exposure. The action of Pb on glutamate release, NMDA receptor function, or structural plasticity may underlie perturbations in synaptic plasticity and contribute to learning impairments. In addition to providing insight into potential mechanisms of Pb-induced cognitive deficits, cellular models offer an opportunity to investigate direct effects of Pb on isolated biological substrates. A target of interest is the 78-kDa molecular chaperone glucose-regulated protein (GRP78). GRP78 chaperones the secretion of the cytokine interleukin-6 (IL-6) by astrocytes. In vitro evidence shows that Pb strongly binds to GRP78, induces GRP78 aggregation, and blocks IL-6 secretion in astroglial cells. These findings provide evidence for a significant chaperone deficiency in Pb-exposed astrocytes in culture. In the long term, chaperone deficiency could underlie protein conformational diseases such as Alzheimer's Disease (AD). Lead exposure in early life has been implicated in subsequent progression of amyloidogenesis in rodents during old age. This exposure resulted in an increase in proteins associated with AD pathology viz., beta-amyloid precursor protein ( beta -APP), and beta-amyloid (A beta ). These four new lines of research comprise compelling evidence that exposures to Pb have adverse effects on the nervous system, that environmental factors increase nervous system susceptibility to Pb, and that exposures in early life may cause neurodegeneration in later life. JF - Toxicology and Applied Pharmacology AU - White, L D AU - Cory-Slechta, DA AU - Gilbert, ME AU - Tiffany-Castiglioni, E AU - Zawia, N H AU - Virgolini, M AU - Rossi-George, A AU - Lasley, S M AU - Qian, Y C AU - Basha, MdR AD - U.S. Environmental Protection Agency, Research Triangle Park, NC, USA, white.lori@epa.gov Y1 - 2007/11/15/ PY - 2007 DA - 2007 Nov 15 SP - 1 EP - 27 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 225 IS - 1 SN - 0041-008X, 0041-008X KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Interleukin 6 KW - N-Methyl-D-aspartic acid receptors KW - Astrocytes KW - Receptor mechanisms KW - Hippocampus KW - Heavy metals KW - Alzheimer's disease KW - Animal models KW - Cell culture KW - Plasticity (synaptic) KW - Lead KW - Memory KW - Neurogenesis KW - Nervous system KW - Dopamine KW - Protein deficiency KW - Long-term potentiation KW - Geriatrics KW - beta -Amyloid KW - Brain KW - Stress KW - Glucocorticoids KW - Glutamic acid receptors (ionotropic) KW - Amyloid precursor protein KW - Socio-economic aspects KW - Neurodegenerative diseases KW - Cognitive ability KW - Chaperones KW - Side effects KW - Signal transduction KW - X 24360:Metals KW - N3 11024:Neuroimmunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20418819?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=New+and+evolving+concepts+in+the+neurotoxicology+of+lead&rft.au=White%2C+L+D%3BCory-Slechta%2C+DA%3BGilbert%2C+ME%3BTiffany-Castiglioni%2C+E%3BZawia%2C+N+H%3BVirgolini%2C+M%3BRossi-George%2C+A%3BLasley%2C+S+M%3BQian%2C+Y+C%3BBasha%2C+MdR&rft.aulast=White&rft.aufirst=L&rft.date=2007-11-15&rft.volume=225&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.08.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Interleukin 6; N-Methyl-D-aspartic acid receptors; Receptor mechanisms; Astrocytes; Heavy metals; Hippocampus; Alzheimer's disease; Animal models; Cell culture; Plasticity (synaptic); Lead; Nervous system; Neurogenesis; Memory; Dopamine; Protein deficiency; Geriatrics; Long-term potentiation; beta -Amyloid; Brain; Stress; Glucocorticoids; Glutamic acid receptors (ionotropic); Amyloid precursor protein; Neurodegenerative diseases; Socio-economic aspects; Cognitive ability; Chaperones; Side effects; Signal transduction DO - http://dx.doi.org/10.1016/j.taap.2007.08.001 ER - TY - CPAPER T1 - Potential Mechanisms in Asbestos-Induced Carcinogenicity: The Role of Reactive Oxygen Species in Adverse Health Effects T2 - 14th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM 2007) AN - 40703402; 4755800 JF - 14th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM 2007) AU - Gwinn, Maureen AU - Guyton, Kate AU - Sonawane, Bob AU - DeVoney, Danielle Y1 - 2007/11/14/ PY - 2007 DA - 2007 Nov 14 KW - Reactive oxygen species KW - Carcinogenicity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40703402?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Annual+Meeting+of+the+Society+for+Free+Radical+Biology+and+Medicine+%28SFRBM+2007%29&rft.atitle=Potential+Mechanisms+in+Asbestos-Induced+Carcinogenicity%3A+The+Role+of+Reactive+Oxygen+Species+in+Adverse+Health+Effects&rft.au=Gwinn%2C+Maureen%3BGuyton%2C+Kate%3BSonawane%2C+Bob%3BDeVoney%2C+Danielle&rft.aulast=Gwinn&rft.aufirst=Maureen&rft.date=2007-11-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Annual+Meeting+of+the+Society+for+Free+Radical+Biology+and+Medicine+%28SFRBM+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/sfrbm2007/Itinerary/SearchResults.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Case Study of Contaminated Groundwater Discharge: How in Situ Tools Link an Evolving Conceptual Site Model with Management Decisions. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40770185; 4778713 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Greenberg, M S AU - Duncan, P AU - Williams, J AU - Black, C AU - Leja, S AU - Wilhelm, L AU - Henry, R G Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Case studies KW - Groundwater pollution KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40770185?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Case+Study+of+Contaminated+Groundwater+Discharge%3A+How+in+Situ+Tools+Link+an+Evolving+Conceptual+Site+Model+with+Management+Decisions.&rft.au=Greenberg%2C+M+S%3BDuncan%2C+P%3BWilliams%2C+J%3BBlack%2C+C%3BLeja%2C+S%3BWilhelm%2C+L%3BHenry%2C+R+G&rft.aulast=Greenberg&rft.aufirst=M&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Ecological Community-Level Responses to Experimental EE-2 and Trenbolone Gradients in Stream Mesocosm Experiments. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40767812; 4778921 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Taulbee, W K AU - Nietch, C AU - Brown, D AU - Flick, R AU - Lazorchak, J AU - Ramakrishnan, B AU - Tompkins, M AU - Smith, M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Trenbolone KW - Streams KW - Mesocosms KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767812?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Ecological+Community-Level+Responses+to+Experimental+EE-2+and+Trenbolone+Gradients+in+Stream+Mesocosm+Experiments.&rft.au=Taulbee%2C+W+K%3BNietch%2C+C%3BBrown%2C+D%3BFlick%2C+R%3BLazorchak%2C+J%3BRamakrishnan%2C+B%3BTompkins%2C+M%3BSmith%2C+M&rft.aulast=Taulbee&rft.aufirst=W&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - EPA Involvement in Risk Assessment at Hanford. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40767670; 4778892 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Gadbois, L E Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - USA, Washington, Hanford KW - Risk assessment KW - EPA KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767670?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=EPA+Involvement+in+Risk+Assessment+at+Hanford.&rft.au=Gadbois%2C+L+E&rft.aulast=Gadbois&rft.aufirst=L&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Overview of Regulatory Tools and Voluntary Stewardship Efforts to Address Pharmaceutical Disposal. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40767472; 4778807 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ruhuy, I Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Reviews KW - Pharmaceuticals KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767472?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Overview+of+Regulatory+Tools+and+Voluntary+Stewardship+Efforts+to+Address+Pharmaceutical+Disposal.&rft.au=Ruhuy%2C+I&rft.aulast=Ruhuy&rft.aufirst=I&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of the Vitellogenin Gene in Early Life Stage Fathead Minnows as an Effective Exposure Indicator for Estrogenic Compounds. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40765069; 4778667 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Lazorchak, J AU - Lattier, D AU - Reddy, T AU - Bencic, D AU - Biales, A AU - Smith, M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Estrogens KW - Vitellogenin KW - Developmental stages KW - Freshwater fish KW - Sex hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40765069?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Induction+of+the+Vitellogenin+Gene+in+Early+Life+Stage+Fathead+Minnows+as+an+Effective+Exposure+Indicator+for+Estrogenic+Compounds.&rft.au=Lazorchak%2C+J%3BLattier%2C+D%3BReddy%2C+T%3BBencic%2C+D%3BBiales%2C+A%3BSmith%2C+M&rft.aulast=Lazorchak&rft.aufirst=J&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bacterial Mortality due to Solar Radiation, Comparing Experimental and Statistical Evidence. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40763396; 4778781 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Frick, W AU - Ge, Z. Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Solar radiation KW - Mortality KW - Statistics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40763396?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Bacterial+Mortality+due+to+Solar+Radiation%2C+Comparing+Experimental+and+Statistical+Evidence.&rft.au=Frick%2C+W%3BGe%2C+Z.&rft.aulast=Frick&rft.aufirst=W&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Optimizing Remedy Decision-Making for Contaminated Sediments under Superfund. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40763264; 4778730 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Logan, M P AU - Evison, L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Superfund KW - Sediment pollution KW - Decision making KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40763264?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Optimizing+Remedy+Decision-Making+for+Contaminated+Sediments+under+Superfund.&rft.au=Logan%2C+M+P%3BEvison%2C+L&rft.aulast=Logan&rft.aufirst=M&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Effect of Dietary and Waterborne Arsenic on Swim-Up Rainbow Trout and Fathead Minnows. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40763120; 4779088 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Hockett, R AU - Erickson, R J AU - Highland, T L AU - Jenson, C T AU - Mount, D R Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Diets KW - Arsenic KW - Freshwater fish KW - Oncorhynchus mykiss KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40763120?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=The+Effect+of+Dietary+and+Waterborne+Arsenic+on+Swim-Up+Rainbow+Trout+and+Fathead+Minnows.&rft.au=Hockett%2C+R%3BErickson%2C+R+J%3BHighland%2C+T+L%3BJenson%2C+C+T%3BMount%2C+D+R&rft.aulast=Hockett&rft.aufirst=R&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Predictive Modeling of Light-Induced Mortality of Enterococci Faecalis in Recreational Waters. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40762965; 4778780 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Zepp, R G AU - Cyterski, M AU - Molina, M AU - Jones, R Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Recreation areas KW - Mortality KW - Light effects KW - Prediction KW - Recreational waters KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40762965?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Predictive+Modeling+of+Light-Induced+Mortality+of+Enterococci+Faecalis+in+Recreational+Waters.&rft.au=Zepp%2C+R+G%3BCyterski%2C+M%3BMolina%2C+M%3BJones%2C+R&rft.aulast=Zepp&rft.aufirst=R&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of Perfluorinated Compounds (PFCs) in Fish Fillet Homogenate by Liquid Chromatography and Tandem Mass Spectrometry. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40762557; 4778545 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Delinsky, A AU - Strynar, M AU - Lindstrom, A AU - Varns, J AU - Nakayama, S AU - Ye, X. Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Mass spectroscopy KW - Liquid chromatography KW - Fish fillets KW - Chromatography KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40762557?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Analysis+of+Perfluorinated+Compounds+%28PFCs%29+in+Fish+Fillet+Homogenate+by+Liquid+Chromatography+and+Tandem+Mass+Spectrometry.&rft.au=Delinsky%2C+A%3BStrynar%2C+M%3BLindstrom%2C+A%3BVarns%2C+J%3BNakayama%2C+S%3BYe%2C+X.&rft.aulast=Delinsky&rft.aufirst=A&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Monitoring of Remedy Effectiveness in Contaminated Sediments Management. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40761787; 4778821 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Greenberg, M S Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Sediment pollution KW - Pollution monitoring KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40761787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Monitoring+of+Remedy+Effectiveness+in+Contaminated+Sediments+Management.&rft.au=Greenberg%2C+M+S&rft.aulast=Greenberg&rft.aufirst=M&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Levels of Synthetic Musk Compounds in Municipal Wastewater for Estimation of Biota Exposure in Receiving Waters. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40761734; 4778791 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Osemwengie, L I Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Biota KW - Municipal wastewater KW - Waste water KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40761734?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Levels+of+Synthetic+Musk+Compounds+in+Municipal+Wastewater+for+Estimation+of+Biota+Exposure+in+Receiving+Waters.&rft.au=Osemwengie%2C+L+I&rft.aulast=Osemwengie&rft.aufirst=L&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - USEPA Office of Water Regulatory Tools to Address Emerging Contaminants in Drinking Water. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40761722; 4778808 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Conerly, O Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Drinking water KW - Contaminants KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40761722?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=USEPA+Office+of+Water+Regulatory+Tools+to+Address+Emerging+Contaminants+in+Drinking+Water.&rft.au=Conerly%2C+O&rft.aulast=Conerly&rft.aufirst=O&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Experts Scientific Workshop on Critical Research and Science Needs for the Development of Recreational Water Quality Criteria. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40761707; 4778784 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ravenscroft, J E Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Recreation areas KW - Water quality KW - Recreational waters KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40761707?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Experts+Scientific+Workshop+on+Critical+Research+and+Science+Needs+for+the+Development+of+Recreational+Water+Quality+Criteria.&rft.au=Ravenscroft%2C+J+E&rft.aulast=Ravenscroft&rft.aufirst=J&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Overview of Emerging Pollutants Issues. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40761676; 4778803 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ohanian, E Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Pollutants KW - Reviews KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40761676?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Overview+of+Emerging+Pollutants+Issues.&rft.au=Ohanian%2C+E&rft.aulast=Ohanian&rft.aufirst=E&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Problem Formulation for Species-Specific Ecological Risk Assessments. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40761594; 4778745 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Brown, P Doelling AU - Pease, A AU - Corbin, M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40761594?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Problem+Formulation+for+Species-Specific+Ecological+Risk+Assessments.&rft.au=Brown%2C+P+Doelling%3BPease%2C+A%3BCorbin%2C+M&rft.aulast=Brown&rft.aufirst=P&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Residue-Effects Database for Polychlorinated Biphenyls, Polychlorinated Dibenzofurans, and Polychlorinated Dibenzo-p-dioxins. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760949; 4779409 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Burkhard, L P AU - Russom, C L AU - Hoff, D J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - PCB KW - Polychlorinated biphenyls KW - Polychlorinated dibenzofurans KW - Databases KW - Dibenzo-p-dioxin KW - Chlorinated hydrocarbons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=A+Residue-Effects+Database+for+Polychlorinated+Biphenyls%2C+Polychlorinated+Dibenzofurans%2C+and+Polychlorinated+Dibenzo-p-dioxins.&rft.au=Burkhard%2C+L+P%3BRussom%2C+C+L%3BHoff%2C+D+J&rft.aulast=Burkhard&rft.aufirst=L&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - US EPA Tools and Databases: Opportunity for Industry to Reapply to Support REACH Compliance. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760842; 4778834 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Libelo, L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Compliance KW - EPA KW - Databases KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760842?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=US+EPA+Tools+and+Databases%3A+Opportunity+for+Industry+to+Reapply+to+Support+REACH+Compliance.&rft.au=Libelo%2C+L&rft.aulast=Libelo&rft.aufirst=L&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Great Lakes Fish Contaminant Laboratory Performance Study. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760796; 4779683 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Murphy, E AU - Backus, S Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - North America, Great Lakes KW - Lakes KW - Contaminants KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760796?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Great+Lakes+Fish+Contaminant+Laboratory+Performance+Study.&rft.au=Murphy%2C+E%3BBackus%2C+S&rft.aulast=Murphy&rft.aufirst=E&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Stochastic Population Model for Narrow Mouthed Toads: Effects of Multiple Stressors on Population Projections. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760708; 4779348 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Salice, C J AU - Rowe, C L AU - Hopkins, W A Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toads KW - Stochasticity KW - Mathematical models KW - Amphibia KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760708?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=A+Stochastic+Population+Model+for+Narrow+Mouthed+Toads%3A+Effects+of+Multiple+Stressors+on+Population+Projections.&rft.au=Salice%2C+C+J%3BRowe%2C+C+L%3BHopkins%2C+W+A&rft.aulast=Salice&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sex Reversal of the Amphibian, Xenopus Tropicalis, Following Larval Exposure to an Aromatase Inhibitor. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760428; 4779437 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Olmstead, A AU - Holcombe, G W AU - Kosian, P A AU - Korte, J J AU - Bennett, B A AU - Woodis, K K AU - Ostazeski, S AU - Degitz, S J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Larvae KW - Amphibians KW - Sex reversal KW - Aromatase KW - Amphibiotic species KW - Inhibitors KW - Xenopus tropicalis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760428?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Sex+Reversal+of+the+Amphibian%2C+Xenopus+Tropicalis%2C+Following+Larval+Exposure+to+an+Aromatase+Inhibitor.&rft.au=Olmstead%2C+A%3BHolcombe%2C+G+W%3BKosian%2C+P+A%3BKorte%2C+J+J%3BBennett%2C+B+A%3BWoodis%2C+K+K%3BOstazeski%2C+S%3BDegitz%2C+S+J&rft.aulast=Olmstead&rft.aufirst=A&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Epa's National Study of Chemical Residues in Lake Fish Tissue Report. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760364; 4779381 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Stahl, L L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Residues KW - Lakes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760364?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Epa%27s+National+Study+of+Chemical+Residues+in+Lake+Fish+Tissue+Report.&rft.au=Stahl%2C+L+L&rft.aulast=Stahl&rft.aufirst=L&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Toxicity Equivalency Values (TEQs) for Polychlorinated Biphenyl Mixtures. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760292; 4779415 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Lukasewycz, M T AU - Burkhard, L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - PCB KW - Polychlorinated biphenyls KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760292?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Toxicity+Equivalency+Values+%28TEQs%29+for+Polychlorinated+Biphenyl+Mixtures.&rft.au=Lukasewycz%2C+M+T%3BBurkhard%2C+L&rft.aulast=Lukasewycz&rft.aufirst=M&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Utility of Genomics and High-Throughput Approaches for the Assessment of Industrial Chemicals and Pesticides. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760276; 4778680 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Henry, T R AU - Holmes, J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Pesticides KW - Chemicals KW - Genomics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760276?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Utility+of+Genomics+and+High-Throughput+Approaches+for+the+Assessment+of+Industrial+Chemicals+and+Pesticides.&rft.au=Henry%2C+T+R%3BHolmes%2C+J&rft.aulast=Henry&rft.aufirst=T&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of a Novel Mechanism of Endocrine Disruption in the Fathead Minnow. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760236; 4779360 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Kahl, M D AU - Blake, L AU - Brodin, J AU - Durhan, E AU - Jensen, K AU - Villeneuve, D AU - Ankley, G AU - Bencic, D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Endocrine disruptors KW - Freshwater fish KW - Endocrinology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760236?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Evaluation+of+a+Novel+Mechanism+of+Endocrine+Disruption+in+the+Fathead+Minnow.&rft.au=Kahl%2C+M+D%3BBlake%2C+L%3BBrodin%2C+J%3BDurhan%2C+E%3BJensen%2C+K%3BVilleneuve%2C+D%3BAnkley%2C+G%3BBencic%2C+D&rft.aulast=Kahl&rft.aufirst=M&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Completion of a Short-Term Reproduction Test for Identifying Endocrine-Disrupting Chemicals. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760215; 4779359 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Jensen, K M AU - Blake, L S AU - Brodin, J D AU - Durhan, E J AU - Hornung, M W AU - Kahl, M D AU - Korte, J J AU - Makynen, E A AU - Martinovic, D AU - Villeneuve, D L AU - Ankley, G T Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Reproduction KW - Chemicals KW - Endocrine disruptors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760215?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Completion+of+a+Short-Term+Reproduction+Test+for+Identifying+Endocrine-Disrupting+Chemicals.&rft.au=Jensen%2C+K+M%3BBlake%2C+L+S%3BBrodin%2C+J+D%3BDurhan%2C+E+J%3BHornung%2C+M+W%3BKahl%2C+M+D%3BKorte%2C+J+J%3BMakynen%2C+E+A%3BMartinovic%2C+D%3BVilleneuve%2C+D+L%3BAnkley%2C+G+T&rft.aulast=Jensen&rft.aufirst=K&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Framework for Application of the Toxicity Equivalence Methodology for PCDDs, PCDFs and PCBs in Ecological Risk Assessment. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760111; 4778592 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Henry, T R AU - Cook, P AU - Cirone, P AU - DeVito, M AU - Duncan, B AU - Pepin, R AU - Schappelle, S AU - Wharton, S Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - Risk assessment KW - PCB KW - PCDF KW - PCDD KW - Polychlorinated biphenyls KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760111?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Framework+for+Application+of+the+Toxicity+Equivalence+Methodology+for+PCDDs%2C+PCDFs+and+PCBs+in+Ecological+Risk+Assessment.&rft.au=Henry%2C+T+R%3BCook%2C+P%3BCirone%2C+P%3BDeVito%2C+M%3BDuncan%2C+B%3BPepin%2C+R%3BSchappelle%2C+S%3BWharton%2C+S&rft.aulast=Henry&rft.aufirst=T&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - USEPA Office of Water Regulatory Tools to Address Emerging Contaminants in the Aquatic Environment. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760039; 4778809 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Eignor, D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Aquatic environment KW - Contaminants KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760039?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=USEPA+Office+of+Water+Regulatory+Tools+to+Address+Emerging+Contaminants+in+the+Aquatic+Environment.&rft.au=Eignor%2C+D&rft.aulast=Eignor&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Panel Session on Addressing Emerging Contaminant Risk. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40760023; 4778806 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ohanian, E AU - Eignor, D AU - Beaman, J AU - Conerly, O Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Contaminants KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760023?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Panel+Session+on+Addressing+Emerging+Contaminant+Risk.&rft.au=Ohanian%2C+E%3BEignor%2C+D%3BBeaman%2C+J%3BConerly%2C+O&rft.aulast=Ohanian&rft.aufirst=E&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Results of a Wildlife Toxicology Workshop Held by the Smithsonian Institution - Identification and Prioritization of Problem Statements. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40759996; 4779309 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Grim, K C AU - Fairbrother, A AU - Monfort, S AU - Tan, S AU - Rattner, B AU - Gerould, S AU - Beasley, V AU - Aguirre, A AU - Rowles, T Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Wildlife KW - Toxicology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40759996?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Results+of+a+Wildlife+Toxicology+Workshop+Held+by+the+Smithsonian+Institution+-+Identification+and+Prioritization+of+Problem+Statements.&rft.au=Grim%2C+K+C%3BFairbrother%2C+A%3BMonfort%2C+S%3BTan%2C+S%3BRattner%2C+B%3BGerould%2C+S%3BBeasley%2C+V%3BAguirre%2C+A%3BRowles%2C+T&rft.aulast=Grim&rft.aufirst=K&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Predicting Chemical Hydrolysis. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40759839; 4779280 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Boethling, R S AU - Meylan, W M AU - Howard, P H Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Hydrolysis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40759839?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Predicting+Chemical+Hydrolysis.&rft.au=Boethling%2C+R+S%3BMeylan%2C+W+M%3BHoward%2C+P+H&rft.aulast=Boethling&rft.aufirst=R&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Water Quality Criteria for Emerging Contaminants: Options and Opportunities. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40759709; 4778811 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Beaman, J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Water quality criteria KW - Contaminants KW - Water quality KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40759709?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Water+Quality+Criteria+for+Emerging+Contaminants%3A+Options+and+Opportunities.&rft.au=Beaman%2C+J&rft.aulast=Beaman&rft.aufirst=J&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Significance of Non-Aqueous Phases in Assessing the Toxicity of Contaminated Sediments. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40759607; 4779209 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Mount, D R AU - Heinis, L J AU - Highland, T L AU - Hockett, R AU - Hoff, D J AU - Jenson, C T AU - Norberg-King, T J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - Sediment pollution KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40759607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=The+Significance+of+Non-Aqueous+Phases+in+Assessing+the+Toxicity+of+Contaminated+Sediments.&rft.au=Mount%2C+D+R%3BHeinis%2C+L+J%3BHighland%2C+T+L%3BHockett%2C+R%3BHoff%2C+D+J%3BJenson%2C+C+T%3BNorberg-King%2C+T+J&rft.aulast=Mount&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Post Remediation Monitoring at Sediment Sites Remediated under the Great Lakes Legacy Act. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40759294; 4778823 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ireland, S AU - Tuchman, M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - North America, Great Lakes KW - Bioremediation KW - Sediment pollution KW - Lakes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40759294?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Post+Remediation+Monitoring+at+Sediment+Sites+Remediated+under+the+Great+Lakes+Legacy+Act.&rft.au=Ireland%2C+S%3BTuchman%2C+M&rft.aulast=Ireland&rft.aufirst=S&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - On-Line Toxicity Monitors and Physical/Chemical Probe Responses to Sodium Fluoroacetate, Potassium Cyanide, and Malathion. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40758944; 4778567 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Allen, J AU - Hall, J AU - Macke, D AU - Muhammed, N AU - Meiners, G Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - Sodium KW - Cyanide KW - Malathion KW - Potassium KW - Probes KW - Potassium cyanide KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40758944?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=On-Line+Toxicity+Monitors+and+Physical%2FChemical+Probe+Responses+to+Sodium+Fluoroacetate%2C+Potassium+Cyanide%2C+and+Malathion.&rft.au=Allen%2C+J%3BHall%2C+J%3BMacke%2C+D%3BMuhammed%2C+N%3BMeiners%2C+G&rft.aulast=Allen&rft.aufirst=J&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Integrative Environmental Assessment via MIRA: Decision Making using Public Health and Ecosystem Indicators. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40758776; 4778284 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Stahl, C AU - Cimorelli, A AU - Nicholson, M AU - Mazzarella, C Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Public health KW - Environmental assessment KW - Decision making KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40758776?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Integrative+Environmental+Assessment+via+MIRA%3A+Decision+Making+using+Public+Health+and+Ecosystem+Indicators.&rft.au=Stahl%2C+C%3BCimorelli%2C+A%3BNicholson%2C+M%3BMazzarella%2C+C&rft.aulast=Stahl&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assessment of Vegetated Agricultural Drainage Ditches for Irrigation Runoff Mitigation in California. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40758494; 4778455 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Denton, D L AU - Moore, M T AU - Cooper, C M AU - Wrysinski, J AU - Robins, P AU - Miller, J L AU - Reece, K AU - Crane, D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - USA, California KW - Irrigation KW - Mitigation KW - Agricultural runoff KW - Drainage KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40758494?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Assessment+of+Vegetated+Agricultural+Drainage+Ditches+for+Irrigation+Runoff+Mitigation+in+California.&rft.au=Denton%2C+D+L%3BMoore%2C+M+T%3BCooper%2C+C+M%3BWrysinski%2C+J%3BRobins%2C+P%3BMiller%2C+J+L%3BReece%2C+K%3BCrane%2C+D&rft.aulast=Denton&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Designing Small Molecules for Biodegradability. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40757727; 4778269 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Boethling, R S AU - Sommer, E AU - DiFiore, D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Biodegradation KW - Biodegradability KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40757727?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Designing+Small+Molecules+for+Biodegradability.&rft.au=Boethling%2C+R+S%3BSommer%2C+E%3BDiFiore%2C+D&rft.aulast=Boethling&rft.aufirst=R&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Metabolomics as a Tool for Discriminating among Adaptive, Compensatory, and Toxic Responses Upon Exposure of Small Fish to EDCs. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40757698; 4778996 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ekman, D R AU - Collette, T W AU - Teng, Q AU - Ankley, G T AU - Martinovic, D AU - Jensen, K M AU - Villeneuve, D L AU - Kahl, M D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Metabolomics KW - Toxicity testing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40757698?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Metabolomics+as+a+Tool+for+Discriminating+among+Adaptive%2C+Compensatory%2C+and+Toxic+Responses+Upon+Exposure+of+Small+Fish+to+EDCs.&rft.au=Ekman%2C+D+R%3BCollette%2C+T+W%3BTeng%2C+Q%3BAnkley%2C+G+T%3BMartinovic%2C+D%3BJensen%2C+K+M%3BVilleneuve%2C+D+L%3BKahl%2C+M+D&rft.aulast=Ekman&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenyl Ethers (PBDEs) in Current and Historical Samples of Avian Eggs from Nesting Sites in Buzzards Bay, MA, USA. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40757277; 4779473 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Jayaraman, S AU - Cantwell, M C AU - Nacci, D E AU - Mostello, C S AU - Nisbet, I C Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - USA KW - USA, Massachusetts, Buzzards Bay KW - PCB KW - Polybrominated diphenyl ethers KW - Historical account KW - Eggs KW - Polychlorinated biphenyls KW - Nesting KW - Reproductive behavior KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40757277?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Polychlorinated+Biphenyls+%28PCBs%29+and+Polybrominated+Diphenyl+Ethers+%28PBDEs%29+in+Current+and+Historical+Samples+of+Avian+Eggs+from+Nesting+Sites+in+Buzzards+Bay%2C+MA%2C+USA.&rft.au=Jayaraman%2C+S%3BCantwell%2C+M+C%3BNacci%2C+D+E%3BMostello%2C+C+S%3BNisbet%2C+I+C&rft.aulast=Jayaraman&rft.aufirst=S&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An Analysis of Ecotoxicity Test Results for Pesticides Available in the ECOTOX Database. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40757163; 4779429 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Russom, C AU - Odenkirchen, E Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Pesticides KW - Databases KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40757163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=An+Analysis+of+Ecotoxicity+Test+Results+for+Pesticides+Available+in+the+ECOTOX+Database.&rft.au=Russom%2C+C%3BOdenkirchen%2C+E&rft.aulast=Russom&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Stressor Identification in Urbanized Watersheds. S.B. Norton, T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756676; 4778945 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ziegler, C R AU - Schofield, K A AU - Varricchione, J T Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Watersheds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756676?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Stressor+Identification+in+Urbanized+Watersheds.+S.B.+Norton%2C&rft.au=Ziegler%2C+C+R%3BSchofield%2C+K+A%3BVarricchione%2C+J+T&rft.aulast=Ziegler&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Determination of Ecologically Relevant Pharmaceuticals and Selected Metabolites in Effl Uent and Surface Water using UPLC/MS/ MS. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756613; 4779075 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Batt, A L AU - Kostich, M AU - Lazorchak, J M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Surface water KW - Metabolites KW - Pharmaceuticals KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756613?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Determination+of+Ecologically+Relevant+Pharmaceuticals+and+Selected+Metabolites+in+Effl+Uent+and+Surface+Water+using+UPLC%2FMS%2F+MS.&rft.au=Batt%2C+A+L%3BKostich%2C+M%3BLazorchak%2C+J+M&rft.aulast=Batt&rft.aufirst=A&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An Overview of U.S. EPAs High Production Volume Challenge Program. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756421; 4779008 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Suski, J G AU - Northrop, R AU - Sonawane, M AU - Henry, T AU - Hernandez, O AU - Townsend, M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - USA KW - EPA KW - Reviews KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756421?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=An+Overview+of+U.S.+EPAs+High+Production+Volume+Challenge+Program.&rft.au=Suski%2C+J+G%3BNorthrop%2C+R%3BSonawane%2C+M%3BHenry%2C+T%3BHernandez%2C+O%3BTownsend%2C+M&rft.aulast=Suski&rft.aufirst=J&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Hypoxia Alters Gene Expression in the Gonads of Zebrafish. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756260; 4779355 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Martinovic, D AU - Villeneuve, D L AU - Kahl, M D AU - Brodin, J D AU - Blake, L S AU - Ankley, G T Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Hypoxia KW - Gonads KW - Gene expression KW - Freshwater fish KW - Danio rerio KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756260?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Hypoxia+Alters+Gene+Expression+in+the+Gonads+of+Zebrafish.&rft.au=Martinovic%2C+D%3BVilleneuve%2C+D+L%3BKahl%2C+M+D%3BBrodin%2C+J+D%3BBlake%2C+L+S%3BAnkley%2C+G+T&rft.aulast=Martinovic&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of an Amphibian Reproductive Assay: Baseline Data on the Tropical Clawed Frog, Xenopus Tropicalis. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756160; 4779438 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Woodis, K K AU - Olmstead, A AU - Bennett, B A AU - Korte, J J AU - Ostazeski, S AU - Degitz, S J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Frogs KW - Amphibians KW - Biological development KW - Amphibiotic species KW - Baseline studies KW - Xenopus tropicalis KW - Anura KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Development+of+an+Amphibian+Reproductive+Assay%3A+Baseline+Data+on+the+Tropical+Clawed+Frog%2C+Xenopus+Tropicalis.&rft.au=Woodis%2C+K+K%3BOlmstead%2C+A%3BBennett%2C+B+A%3BKorte%2C+J+J%3BOstazeski%2C+S%3BDegitz%2C+S+J&rft.aulast=Woodis&rft.aufirst=K&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Adding Ecological Realism to Plant Testing. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756121; 4779452 DE: JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Pfleeger, T G AU - Blakeley-Smith, M AU - Olszyk, D AU - Plocher, M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756121?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Adding+Ecological+Realism+to+Plant+Testing.&rft.au=Pfleeger%2C+T+G%3BBlakeley-Smith%2C+M%3BOlszyk%2C+D%3BPlocher%2C+M&rft.aulast=Pfleeger&rft.aufirst=T&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - HPLC-ICPMS Analysis of Thyroid Hormone and Related Iodinated Compounds in Tissues and Media. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756083; 4779420 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Butterworth, B C AU - Hammermeister, D E AU - Kosian, P A AU - Haselman, J T AU - Degitz, S J AU - Tietge, J E Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Hormones KW - Thyroid hormones KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756083?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=HPLC-ICPMS+Analysis+of+Thyroid+Hormone+and+Related+Iodinated+Compounds+in+Tissues+and+Media.&rft.au=Butterworth%2C+B+C%3BHammermeister%2C+D+E%3BKosian%2C+P+A%3BHaselman%2C+J+T%3BDegitz%2C+S+J%3BTietge%2C+J+E&rft.aulast=Butterworth&rft.aufirst=B&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Amphibian Metamorphosis Assay Thyroid Histopathology: Approach to Reading Studies, Diagnostic Criteria, Severity Grading, and Atlas. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40756055; 4779413 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Grim, K C AU - Touart, L W Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Histopathology KW - Metamorphosis KW - Thyroid KW - Amphibians KW - Atlases KW - Grading KW - Life cycle KW - Amphibiotic species KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40756055?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Amphibian+Metamorphosis+Assay+Thyroid+Histopathology%3A+Approach+to+Reading+Studies%2C+Diagnostic+Criteria%2C+Severity+Grading%2C+and+Atlas.&rft.au=Grim%2C+K+C%3BTouart%2C+L+W&rft.aulast=Grim&rft.aufirst=K&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Overview of Exposure to Dioxin-Like Compounds and PCBs on Developmental, Immunosuppressive, and Hormone-Related Effects in Mammals, Including Humans. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40755970; 4778489 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Birnbaum, L S Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Dioxin KW - PCB KW - Mammals KW - Reviews KW - Polychlorinated biphenyls KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755970?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Overview+of+Exposure+to+Dioxin-Like+Compounds+and+PCBs+on+Developmental%2C+Immunosuppressive%2C+and+Hormone-Related+Effects+in+Mammals%2C+Including+Humans.&rft.au=Birnbaum%2C+L+S&rft.aulast=Birnbaum&rft.aufirst=L&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Thyroid Peroxidase Inhibition as a Tool to Select Chemicals for Testing in Amphibian-Based Thyroid Toxicity Assays. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40755704; 4779333 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Hornung, M W AU - Haselman, J T AU - Tietge, J E AU - Degitz, S E AU - Korte, L M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity testing KW - Thyroid KW - Chemicals KW - Iodide peroxidase KW - Bioaccumulation KW - Pollution indicators KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755704?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Thyroid+Peroxidase+Inhibition+as+a+Tool+to+Select+Chemicals+for+Testing+in+Amphibian-Based+Thyroid+Toxicity+Assays.&rft.au=Hornung%2C+M+W%3BHaselman%2C+J+T%3BTietge%2C+J+E%3BDegitz%2C+S+E%3BKorte%2C+L+M&rft.aulast=Hornung&rft.aufirst=M&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Estimating the Spatial Extent of Potential Secondary Exposure to Pesticides using Allometric Equations. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40755517; 4779140 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Salice, C J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Pesticides KW - Mathematical models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755517?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Estimating+the+Spatial+Extent+of+Potential+Secondary+Exposure+to+Pesticides+using+Allometric+Equations.&rft.au=Salice%2C+C+J&rft.aulast=Salice&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of Arsenic Concentrations in Carcass and Viscera of Swim-Up Rainbow Trout Exposed to Dietary and Waterborne Arsenic. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40755373; 4779089 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Jenson, C T AU - Erickson, R J AU - Highland, T L AU - Hockett, J R AU - Hoff, D J AU - Mount, D R Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Diets KW - Arsenic KW - Viscera KW - Carcasses KW - Oncorhynchus mykiss KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755373?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Comparison+of+Arsenic+Concentrations+in+Carcass+and+Viscera+of+Swim-Up+Rainbow+Trout+Exposed+to+Dietary+and+Waterborne+Arsenic.&rft.au=Jenson%2C+C+T%3BErickson%2C+R+J%3BHighland%2C+T+L%3BHockett%2C+J+R%3BHoff%2C+D+J%3BMount%2C+D+R&rft.aulast=Jenson&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Trilostane on Reproductive Endocrinology of the Fathead Minnow. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40755283; 4779478 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Blake, L S AU - Villeneuve, D L AU - Jensen, K M AU - Martinovic, D AU - Kahl, M D AU - Brodin, J D AU - Makynen, E A AU - Durhan, E J AU - Ankley, G T Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Endocrinology KW - Freshwater fish KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755283?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Effects+of+Trilostane+on+Reproductive+Endocrinology+of+the+Fathead+Minnow.&rft.au=Blake%2C+L+S%3BVilleneuve%2C+D+L%3BJensen%2C+K+M%3BMartinovic%2C+D%3BKahl%2C+M+D%3BBrodin%2C+J+D%3BMakynen%2C+E+A%3BDurhan%2C+E+J%3BAnkley%2C+G+T&rft.aulast=Blake&rft.aufirst=L&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of a Framework for Integrating Tissue Residue-based Toxicity Data into Ecological Risk Assessment. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40755144; 4778962 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Sappington, K AU - Bradbury, S AU - Bridges, T AU - Erickson, R AU - Mount, D AU - Hendriks, J AU - Lanno, R AU - Salazar, M AU - Spry, D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - Risk assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755144?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Development+of+a+Framework+for+Integrating+Tissue+Residue-based+Toxicity+Data+into+Ecological+Risk+Assessment.&rft.au=Sappington%2C+K%3BBradbury%2C+S%3BBridges%2C+T%3BErickson%2C+R%3BMount%2C+D%3BHendriks%2C+J%3BLanno%2C+R%3BSalazar%2C+M%3BSpry%2C+D&rft.aulast=Sappington&rft.aufirst=K&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Moving Beyond a Linear World: Development of a Simplified Modeling Framework for Mercury TMDLs. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40755022; 4779315 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Sunderland, E M AU - Knightes, C D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Mercury KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755022?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Moving+Beyond+a+Linear+World%3A+Development+of+a+Simplified+Modeling+Framework+for+Mercury+TMDLs.&rft.au=Sunderland%2C+E+M%3BKnightes%2C+C+D&rft.aulast=Sunderland&rft.aufirst=E&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Forecasts and Sensitivity of PCB Bioaccumulation in Fish of Lake Hartwell, South Carolina, USA. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40754800; 4778324 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Rashleigh, B AU - Barber, C AU - Walters, D Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - USA, South Carolina KW - Bioaccumulation KW - PCB KW - Lakes KW - Polychlorinated biphenyls KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40754800?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Forecasts+and+Sensitivity+of+PCB+Bioaccumulation+in+Fish+of+Lake+Hartwell%2C+South+Carolina%2C+USA.&rft.au=Rashleigh%2C+B%3BBarber%2C+C%3BWalters%2C+D&rft.aulast=Rashleigh&rft.aufirst=B&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of Markers of Exposure to Copper, Nonylphenol and Atrazine in Daphnia Pulex using Subtractive Hybridization. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40754569; 4779642 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Flick, R AU - Lazorchak, J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Copper KW - Atrazine KW - Herbicides KW - Nonyl phenol KW - Freshwater crustaceans KW - Pollution indicators KW - Toxicity testing KW - Hybridization KW - Daphnia pulex KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40754569?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Development+of+Markers+of+Exposure+to+Copper%2C+Nonylphenol+and+Atrazine+in+Daphnia+Pulex+using+Subtractive+Hybridization.&rft.au=Flick%2C+R%3BLazorchak%2C+J&rft.aulast=Flick&rft.aufirst=R&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Relationships between Sediment Profile Imagery (SPI) and Environmental Variables. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40754521; 4779595 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Boothman, W S AU - Coiro, L AU - Bergen, B J AU - Nelson, W G Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Sediment pollution KW - Environmental factors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40754521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Relationships+between+Sediment+Profile+Imagery+%28SPI%29+and+Environmental+Variables.&rft.au=Boothman%2C+W+S%3BCoiro%2C+L%3BBergen%2C+B+J%3BNelson%2C+W+G&rft.aulast=Boothman&rft.aufirst=W&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Designing Environmentally Friendly Industrial Chemicals. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40754502; 4778270 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Nabholz, J V Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Chemicals KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40754502?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Designing+Environmentally+Friendly+Industrial+Chemicals.&rft.au=Nabholz%2C+J+V&rft.aulast=Nabholz&rft.aufirst=J&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sediment Toxicity Identification and Evaluation (TIE) Phases I, II and III Guidance Document. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40754395; 4779200 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ho, K T AU - Burgess, R M AU - Pelletier, M C AU - Cantwell, M G AU - Serbst, J R AU - Ryba, S A AU - Mount, D R AU - Norberg-King, T J AU - Hockett, R J AU - Perron, M M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - Sediment pollution KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40754395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Sediment+Toxicity+Identification+and+Evaluation+%28TIE%29+Phases+I%2C+II+and+III+Guidance+Document.&rft.au=Ho%2C+K+T%3BBurgess%2C+R+M%3BPelletier%2C+M+C%3BCantwell%2C+M+G%3BSerbst%2C+J+R%3BRyba%2C+S+A%3BMount%2C+D+R%3BNorberg-King%2C+T+J%3BHockett%2C+R+J%3BPerron%2C+M+M&rft.aulast=Ho&rft.aufirst=K&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of a High-Throughput Method for Quantitating Thyroid Gland Follicular Cell Hyperplasia in Amphibian Model Species Xenopus Laevis. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40754347; 4779629 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Haselman, J T AU - Tietge, J E AU - Hornung, M W AU - Degitz, S J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Thyroid KW - Amphibians KW - Hyperplasia KW - Biological development KW - Amphibiotic species KW - Glands KW - Xenopus laevis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40754347?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Development+of+a+High-Throughput+Method+for+Quantitating+Thyroid+Gland+Follicular+Cell+Hyperplasia+in+Amphibian+Model+Species+Xenopus+Laevis.&rft.au=Haselman%2C+J+T%3BTietge%2C+J+E%3BHornung%2C+M+W%3BDegitz%2C+S+J&rft.aulast=Haselman&rft.aufirst=J&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Shifts in Tissue Stable Nitrogen Isotope Ratios Potentially Provide Physical-Traceable Evidence Linking Biochemical Responses to Ecological Consequences. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753854; 4778437 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Shaw-Allen, P L AU - Romanek, C S AU - Jagoe, C H Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Nitrogen isotopes KW - Biochemistry KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753854?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Shifts+in+Tissue+Stable+Nitrogen+Isotope+Ratios+Potentially+Provide+Physical-Traceable+Evidence+Linking+Biochemical+Responses+to+Ecological+Consequences.&rft.au=Shaw-Allen%2C+P+L%3BRomanek%2C+C+S%3BJagoe%2C+C+H&rft.aulast=Shaw-Allen&rft.aufirst=P&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Forecasting Population Impacts using Mechanistic Biomarkers: A Case Study with the Fathead Minnow. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753812; 4778436 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Miller, D H AU - Jensen, K M AU - Villeneuve, D L AU - Kahl, M D AU - Makynen, E A AU - Durhan, E J AU - Ankley, G T Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Case studies KW - Bioindicators KW - Biomarkers KW - Freshwater fish KW - Prediction KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753812?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Forecasting+Population+Impacts+using+Mechanistic+Biomarkers%3A+A+Case+Study+with+the+Fathead+Minnow.&rft.au=Miller%2C+D+H%3BJensen%2C+K+M%3BVilleneuve%2C+D+L%3BKahl%2C+M+D%3BMakynen%2C+E+A%3BDurhan%2C+E+J%3BAnkley%2C+G+T&rft.aulast=Miller&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of In Vivo and In Vitro Chemical Screening Assays for Estrogen-Responsive Protein Biomarker Expression in the Sheepshead Minnow (Cyprinodon variegatus). T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753751; 4778995 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Vickery, S S AU - Harris, P S AU - Salinas, K AU - Walker, C AU - Hemmer, M AU - Ng, J. Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Bioindicators KW - Estrogens KW - Biomarkers KW - Freshwater fish KW - Screening KW - Sex hormones KW - Cyprinodon variegatus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Comparison+of+In+Vivo+and+In+Vitro+Chemical+Screening+Assays+for+Estrogen-Responsive+Protein+Biomarker+Expression+in+the+Sheepshead+Minnow+%28Cyprinodon+variegatus%29.&rft.au=Vickery%2C+S+S%3BHarris%2C+P+S%3BSalinas%2C+K%3BWalker%2C+C%3BHemmer%2C+M%3BNg%2C+J.&rft.aulast=Vickery&rft.aufirst=S&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Using Enantiomer Fractions of Pops to Characterize Contamination, Degradation, and Sources. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753690; 4778406 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Ulrich, E AU - Falconer, R L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Contamination KW - Enantiomers KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Using+Enantiomer+Fractions+of+Pops+to+Characterize+Contamination%2C+Degradation%2C+and+Sources.&rft.au=Ulrich%2C+E%3BFalconer%2C+R+L&rft.aulast=Ulrich&rft.aufirst=E&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Theory and Framework for Environmental Assessment. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753503; 4778279 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Suter, G W AU - Cormier, S M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Environmental assessment KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=A+Theory+and+Framework+for+Environmental+Assessment.&rft.au=Suter%2C+G+W%3BCormier%2C+S+M&rft.aulast=Suter&rft.aufirst=G&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Systematic Approach to Microarray Data Analysis for Biomarker Discovery. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753466; 4778430 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Villeneuve, D L AU - Martinovic, D AU - Ankley, G T AU - Wang, R AU - Knoebl, I AU - Bencic, D C AU - Perkins, E J AU - Vinas, N.G. Reyero Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Bioindicators KW - Data processing KW - Biomarkers KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=A+Systematic+Approach+to+Microarray+Data+Analysis+for+Biomarker+Discovery.&rft.au=Villeneuve%2C+D+L%3BMartinovic%2C+D%3BAnkley%2C+G+T%3BWang%2C+R%3BKnoebl%2C+I%3BBencic%2C+D+C%3BPerkins%2C+E+J%3BVinas%2C+N.G.+Reyero&rft.aulast=Villeneuve&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of Time- And Concentration-Dependent Toxic Effect Models for use in Aquatic Risk Assessments. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753388; 4778253 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Erickson, R J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Risk assessment KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Evaluation+of+Time-+And+Concentration-Dependent+Toxic+Effect+Models+for+use+in+Aquatic+Risk+Assessments.&rft.au=Erickson%2C+R+J&rft.aulast=Erickson&rft.aufirst=R&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - SSDs Derived from Biosurvey Data Provide More Realistic Models of Metal Influences on Invertebrate Populations. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753296; 4779714 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Shaw-Allen, P L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Invertebrates KW - Metals KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753296?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=SSDs+Derived+from+Biosurvey+Data+Provide+More+Realistic+Models+of+Metal+Influences+on+Invertebrate+Populations.&rft.au=Shaw-Allen%2C+P+L&rft.aulast=Shaw-Allen&rft.aufirst=P&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Measured Chemical Concentrations are Key to Interpreting in Vitro Endocrine Disruptor Assay Results. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753255; 4779434 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Sheedy, B R AU - Tapper, M A AU - Denny, J S AU - Kolanczyk, R C AU - Schmieder, P K AU - Toonen, L R AU - Johnson, B J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Endocrine disruptors KW - Endocrinology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753255?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Measured+Chemical+Concentrations+are+Key+to+Interpreting+in+Vitro+Endocrine+Disruptor+Assay+Results.&rft.au=Sheedy%2C+B+R%3BTapper%2C+M+A%3BDenny%2C+J+S%3BKolanczyk%2C+R+C%3BSchmieder%2C+P+K%3BToonen%2C+L+R%3BJohnson%2C+B+J&rft.aulast=Sheedy&rft.aufirst=B&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Social Status Modulates Reproductive Endocrinology and Urine Metabolite Profiles in the Fathead Minnow Males. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753184; 4778541 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Martinovic, D AU - Villeneuve, D L AU - Jensen, K M AU - Blake, L S AU - Kahl, M D AU - Ankley, G T AU - Ekman, D R AU - Teng, Q AU - Collette, T W Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Metabolites KW - Urine KW - Endocrinology KW - Social interactions KW - Freshwater fish KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753184?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Social+Status+Modulates+Reproductive+Endocrinology+and+Urine+Metabolite+Profiles+in+the+Fathead+Minnow+Males.&rft.au=Martinovic%2C+D%3BVilleneuve%2C+D+L%3BJensen%2C+K+M%3BBlake%2C+L+S%3BKahl%2C+M+D%3BAnkley%2C+G+T%3BEkman%2C+D+R%3BTeng%2C+Q%3BCollette%2C+T+W&rft.aulast=Martinovic&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of Weibull Function for Non-Linear Analysis of Effects of Low Levels of Simualted Herbicide Drift on Plants. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753143; 4779404 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Olszyk, D AU - Lee, E AU - Pfleeger, T Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Herbicides KW - Drift KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753143?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Use+of+Weibull+Function+for+Non-Linear+Analysis+of+Effects+of+Low+Levels+of+Simualted+Herbicide+Drift+on+Plants.&rft.au=Olszyk%2C+D%3BLee%2C+E%3BPfleeger%2C+T&rft.aulast=Olszyk&rft.aufirst=D&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Toxicity of Silver Nanoparticles to Daphnia Magna. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40753040; 4779665 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Impellitteri, C AU - Allen, J AU - Macke, D AU - Heckman, L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - Silver KW - Nanoparticles KW - Freshwater crustaceans KW - Daphnia magna KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Toxicity+of+Silver+Nanoparticles+to+Daphnia+Magna.&rft.au=Impellitteri%2C+C%3BAllen%2C+J%3BMacke%2C+D%3BHeckman%2C+L&rft.aulast=Impellitteri&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Water Research Strategy: Research Needed for Aquatic Ecosystem Protection Programs in the Office of Water-US EPA. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40751869; 4778344 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Reiley, M Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Aquatic ecosystems KW - EPA KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40751869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=The+Water+Research+Strategy%3A+Research+Needed+for+Aquatic+Ecosystem+Protection+Programs+in+the+Office+of+Water-US+EPA.&rft.au=Reiley%2C+M&rft.aulast=Reiley&rft.aufirst=M&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identifying Indicators of Reactivity for Chemical Reductants in Anoxic and Anaerobic Sediments. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40751417; 4778411 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Zhang, H AU - Weber, E J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Anoxic sediments KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40751417?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Identifying+Indicators+of+Reactivity+for+Chemical+Reductants+in+Anoxic+and+Anaerobic+Sediments.&rft.au=Zhang%2C+H%3BWeber%2C+E+J&rft.aulast=Zhang&rft.aufirst=H&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Perchlorate Monitoring in California. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40750887; 4778453 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Mayer, K P AU - Holub, R L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - USA, California KW - Perchlorate KW - Perchloric acid KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40750887?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Perchlorate+Monitoring+in+California.&rft.au=Mayer%2C+K+P%3BHolub%2C+R+L&rft.aulast=Mayer&rft.aufirst=K&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gene Expression Biomarkers of Intersexuality in the Amphibian, Xenopus tropicalis. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40750563; 4778534 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Olmstead, A AU - Korte, J J AU - Woodis, K K AU - Bennett, B A AU - Holcombe, G W AU - Kosian, P A AU - Ostazeski, S AU - Degitz, S J AU - Vallanat, B AU - Corton, J Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Bioindicators KW - Amphibians KW - Gene expression KW - Biomarkers KW - Amphibiotic species KW - Xenopus tropicalis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40750563?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Gene+Expression+Biomarkers+of+Intersexuality+in+the+Amphibian%2C+Xenopus+tropicalis.&rft.au=Olmstead%2C+A%3BKorte%2C+J+J%3BWoodis%2C+K+K%3BBennett%2C+B+A%3BHolcombe%2C+G+W%3BKosian%2C+P+A%3BOstazeski%2C+S%3BDegitz%2C+S+J%3BVallanat%2C+B%3BCorton%2C+J&rft.aulast=Olmstead&rft.aufirst=A&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Preliminary Evaluation of the Effects of Coal Fly Ash Amendments on the Toxicity of a Contaminated Marine Sediment. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40750408; 4778486 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Burgess, R M AU - Cantwell, M G AU - Pelletier, M C AU - Ho, K T AU - Serbst, J R AU - Ryba, S A AU - Perron, M M AU - Suuberg, E M AU - Pennell, K G AU - Friedman, C L Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Toxicity KW - Coal KW - Sediment pollution KW - Fly ash KW - Marine pollution KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40750408?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=Preliminary+Evaluation+of+the+Effects+of+Coal+Fly+Ash+Amendments+on+the+Toxicity+of+a+Contaminated+Marine+Sediment.&rft.au=Burgess%2C+R+M%3BCantwell%2C+M+G%3BPelletier%2C+M+C%3BHo%2C+K+T%3BSerbst%2C+J+R%3BRyba%2C+S+A%3BPerron%2C+M+M%3BSuuberg%2C+E+M%3BPennell%2C+K+G%3BFriedman%2C+C+L&rft.aulast=Burgess&rft.aufirst=R&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Review of Bioaccumulation Modeling Approaches for Persistent Organic Pollutants. T2 - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AN - 40750117; 4778318 JF - 28th Annual Meeting of the Society of Environmental Toxicology and Chemistry North America AU - Barber, C AU - Rashleigh, B AU - Munns, W Y1 - 2007/11/11/ PY - 2007 DA - 2007 Nov 11 KW - Bioaccumulation KW - Persistent organic pollutants KW - Reviews KW - Pollutant persistence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40750117?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.atitle=A+Review+of+Bioaccumulation+Modeling+Approaches+for+Persistent+Organic+Pollutants.&rft.au=Barber%2C+C%3BRashleigh%2C+B%3BMunns%2C+W&rft.aulast=Barber&rft.aufirst=C&rft.date=2007-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=28th+Annual+Meeting+of+the+Society+of+Environmental+Toxicology+and+Chemistry+North+America&rft.issn=&rft_id=info:doi/ L2 - http://milwaukee.setac.org/pdf/2007_Abstract_Book.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Cumulative effects of in utero administration of mixtures of ''antiandrogens'' on male rat reproductive development AN - 20911729; 8286061 JF - Toxicology AU - Gray, LE AU - Furr, J AU - Howdeshell, K AU - Hotchkiss, A AU - Wilson, V AU - Rider, C AD - RTD, NHEERL, ORD, USEPA, United Kingdom, gray.earl@epa.gov Y1 - 2007/11/06/ PY - 2007 DA - 2007 Nov 06 SP - 139 EP - 140 PB - Elsevier Science, P.O. Box 85 Limerick Ireland VL - 240 IS - 3 SN - 0300-483X, 0300-483X KW - Toxicology Abstracts KW - antiandrogens KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20911729?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Cumulative+effects+of+in+utero+administration+of+mixtures+of+%27%27antiandrogens%27%27+on+male+rat+reproductive+development&rft.au=Gray%2C+LE%3BFurr%2C+J%3BHowdeshell%2C+K%3BHotchkiss%2C+A%3BWilson%2C+V%3BRider%2C+C&rft.aulast=Gray&rft.aufirst=LE&rft.date=2007-11-06&rft.volume=240&rft.issue=3&rft.spage=139&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2007.06.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-07-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - antiandrogens DO - http://dx.doi.org/10.1016/j.tox.2007.06.021 ER - TY - CPAPER T1 - The U.S. EPAs Multidisciplinary Approach to Examining the Links between Biodiversity and Human Health T2 - 56th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH 2007) AN - 40766597; 4777485 JF - 56th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH 2007) AU - Pongsiri, Montira Y1 - 2007/11/04/ PY - 2007 DA - 2007 Nov 04 KW - USA KW - EPA KW - Biological diversity KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40766597?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=56th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene+%28ASTMH+2007%29&rft.atitle=The+U.S.+EPAs+Multidisciplinary+Approach+to+Examining+the+Links+between+Biodiversity+and+Human+Health&rft.au=Pongsiri%2C+Montira&rft.aulast=Pongsiri&rft.aufirst=Montira&rft.date=2007-11-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=56th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene+%28ASTMH+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/meetings/07abstract/Final_program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Building Healthy Communities for Active Aging: A Public Policy Approach to Improving the Health of Older Adults T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40773911; 4782762 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Sykes, Kathy Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Public policy KW - Aging KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40773911?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=Building+Healthy+Communities+for+Active+Aging%3A+A+Public+Policy+Approach+to+Improving+the+Health+of+Older+Adults&rft.au=Sykes%2C+Kathy&rft.aulast=Sykes&rft.aufirst=Kathy&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - High Pesticide Exposure Events (HPEE): Lessons Learned from the Agricultural Health Study. T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40767816; 4782074 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Allen, Ruth H AU - Mage, David T AU - Kodali, Anuradha Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Pesticides KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767816?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=High+Pesticide+Exposure+Events+%28HPEE%29%3A+Lessons+Learned+from+the+Agricultural+Health+Study.&rft.au=Allen%2C+Ruth+H%3BMage%2C+David+T%3BKodali%2C+Anuradha&rft.aulast=Allen&rft.aufirst=Ruth&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Health Effects of Dioxins T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40767373; 4783518 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - DeVito, Michael Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Dioxin KW - Chlorinated hydrocarbons KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767373?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=Health+Effects+of+Dioxins&rft.au=DeVito%2C+Michael&rft.aulast=DeVito&rft.aufirst=Michael&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Meta-analysis of the Life Style Factors Relevant to Environmental Hazards for the Aging Population T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40764732; 4782746 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Chao, Evelyn AU - McCurdy, Thomas AU - Thomas, Kent AU - Tulve, Nicolle Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Environmental hazards KW - Aging KW - Reviews KW - Hazards KW - Environmental factors KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40764732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=Meta-analysis+of+the+Life+Style+Factors+Relevant+to+Environmental+Hazards+for+the+Aging+Population&rft.au=Chao%2C+Evelyn%3BMcCurdy%2C+Thomas%3BThomas%2C+Kent%3BTulve%2C+Nicolle&rft.aulast=Chao&rft.aufirst=Evelyn&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Exposure to Small Air Particulates (PM2.5) among Asian and Pacific Islander Americans T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40760673; 4782993 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Payne-Sturges, Devon AU - Gee, Gilbert C Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Pacific KW - Particulates KW - Particle size KW - Air exposure KW - Ocean-atmosphere system KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760673?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=Exposure+to+Small+Air+Particulates+%28PM2.5%29+among+Asian+and+Pacific+Islander+Americans&rft.au=Payne-Sturges%2C+Devon%3BGee%2C+Gilbert+C&rft.aulast=Payne-Sturges&rft.aufirst=Devon&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Comprehensive Assessment of Children's Health and Indoor Air Quality in Child Care Settings T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40757190; 4780729 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Brown, Margot AU - Foos, Brenda AU - Knowlton, Carrie AU - Gray, Julia Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Indoor air pollution KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40757190?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=A+Comprehensive+Assessment+of+Children%27s+Health+and+Indoor+Air+Quality+in+Child+Care+Settings&rft.au=Brown%2C+Margot%3BFoos%2C+Brenda%3BKnowlton%2C+Carrie%3BGray%2C+Julia&rft.aulast=Brown&rft.aufirst=Margot&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - EPA's Role in the Collaboration to Support Community-Based Environmental Health Initiatives T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40757138; 4780585 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Gulliford, Jim AU - Brenner, Rob AU - Auer, Charles AU - Jones, Jim Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Community involvement KW - Environmental health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40757138?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=EPA%27s+Role+in+the+Collaboration+to+Support+Community-Based+Environmental+Health+Initiatives&rft.au=Gulliford%2C+Jim%3BBrenner%2C+Rob%3BAuer%2C+Charles%3BJones%2C+Jim&rft.aulast=Gulliford&rft.aufirst=Jim&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Public Health Consequences of Arsenical Antimicrobial Drugs Used in Industrial Poultry Production T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40755184; 4780693 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Nachman, Keeve E Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Public health KW - Poultry KW - Drugs KW - Antimicrobial agents KW - Industrial production KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755184?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=Public+Health+Consequences+of+Arsenical+Antimicrobial+Drugs+Used+in+Industrial+Poultry+Production&rft.au=Nachman%2C+Keeve+E&rft.aulast=Nachman&rft.aufirst=Keeve&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Children's Residential Proximity to Roadways in the Los Angeles, CA Urban Area T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40755117; 4780679 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Miller, Gregory G AU - Axelrad, Daniel A AU - Woodruff, Tracey J Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - USA, California, Los Angeles KW - Urban areas KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755117?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=Children%27s+Residential+Proximity+to+Roadways+in+the+Los+Angeles%2C+CA+Urban+Area&rft.au=Miller%2C+Gregory+G%3BAxelrad%2C+Daniel+A%3BWoodruff%2C+Tracey+J&rft.aulast=Miller&rft.aufirst=Gregory&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An Observational Study on the Potential Exposures of 111 Preschool Children to Phthalates in their Everyday Environments T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40753840; 4780688 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Figueroa, Zaida I AU - Morgan, Marsha K AU - Jones, Paul A AU - Croghan, Carry W AU - Sheldon, Linda S AU - Calafat, Antonia M Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Phthalates KW - Children KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=An+Observational+Study+on+the+Potential+Exposures+of+111+Preschool+Children+to+Phthalates+in+their+Everyday+Environments&rft.au=Figueroa%2C+Zaida+I%3BMorgan%2C+Marsha+K%3BJones%2C+Paul+A%3BCroghan%2C+Carry+W%3BSheldon%2C+Linda+S%3BCalafat%2C+Antonia+M&rft.aulast=Figueroa&rft.aufirst=Zaida&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - EPA Research and Assessment Activities on Climate Change and Human Health T2 - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AN - 40753647; 4780640 JF - 135th Annual Meeting and Exposition of the American Public Health Association (APHA 2007) AU - Grambsch, Anne Y1 - 2007/11/03/ PY - 2007 DA - 2007 Nov 03 KW - Climatic changes KW - EPA KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40753647?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.atitle=EPA+Research+and+Assessment+Activities+on+Climate+Change+and+Human+Health&rft.au=Grambsch%2C+Anne&rft.aulast=Grambsch&rft.aufirst=Anne&rft.date=2007-11-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=135th+Annual+Meeting+and+Exposition+of+the+American+Public+Health+Association+%28APHA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/135am/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Testing antimicrobial cleaner efficacy on gypsum wallboard contaminated with Stachybotrys chartarum AN - 851465945; 14033290 AB - Goal, Scope and Background: Reducing occupant exposure to indoor mold is the goal of this research, through the efficacy testing of antimicrobial cleaners. Often mold contaminated building materials are not properly removed, but instead surface cleaners are applied in an attempt to alleviate the problem. The efficacy of antimicrobial cleaners to remove, eliminate or control mold growth on surfaces can easily be tested on non-porous surfaces. However, the testing of antimicrobial cleaner efficacy on porous surfaces, such as those found in the indoor environment such as gypsum board can be more complicated and prone to incorrect conclusions regarding residual organisms. The mold Stachybotrys chartarum has been found to be associated with idiopathic pulmonary hemorrhage in infants and has been studied for toxin production and its occurrence in water damaged buildings. Growth of S. chartarum on building materials such as gypsum wallboard has been frequently documented. Methods: Research to control S. chartarum growth using 13 separate antimicrobial cleaners on contaminated gypsum wallboard has been performed in laboratory testing. Popular brands of cleaning products were tested by following directions printed on the product packaging. Results: A variety of gypsum wallboard surfaces were used to test these cleaning products at high relative humidity. The results indicate differences in antimicrobial efficacy for the six month period of testing. Discussion: Results for the six types of GWB surfaces varied extensively. However, three cleaning products exhibited significantly better results than others. Lysol All-Purpose Cleaner-Orange Breeze (full strength) demonstrated results which ranked among the best in five of the six surfaces tested. Both Borax and Orange Glo Multipurpose Degreaser demonstrated results which ranked among the best in four of the six surfaces tested. Conclusions: The best antimicrobial cleaner to choose is often dependent on the type of surface to be cleaned of S. chartarum contamination. For Plain GWB, no paint, the best cleaners were Borax, Lysol All-Purpose Cleaner-Orange Breeze (full strength), Orange Glo Multipurpose Degreaser, and Fantastik Orange Action. Recommendations and Perspectives: These results are not meant to endorse the incomplete removal of mold contaminated building materials. However, it is recognized that complete removal may not always be possible and solutions to control mold regrowth may contribute to reduced occupant exposure. Current recommendations of removal and replacement of porous building materials should be followed. It is not the intension of this discussion to endorse any product. Reporting on the performance of these products under the stated conditions was and remains the only purpose. JF - Environmental Science and Pollution Research International AU - Menetrez, Marc Y AU - Foarde, Karin K AU - Webber, Tricia D AU - Dean, Timothy R AU - Betancourt, Doris A AD - Air Pollution Prevention and Control Division, U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, NC, 27711, USA, menetrez.marc@epa.gov Y1 - 2007/11// PY - 2007 DA - November 2007 SP - 523 EP - 528 PB - Ecomed Verlagsgesellschaft AG & Co. KG, Justus-von-Liebig-Strasse 1 Landsberg D-86899 Germany VL - 14 IS - 7 SN - 0944-1344, 0944-1344 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Pollution Abstracts; Environment Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Relative humidity KW - Toxicants KW - Contamination KW - Molds KW - Hemorrhage KW - Toxicity tests KW - Growth KW - gypsum KW - plains KW - Borax KW - Packaging KW - Plains KW - Construction materials KW - Humidity KW - Stachybotrys chartarum KW - Pollution research KW - Toxins KW - Antimicrobial agents KW - Gypsum KW - Lung KW - Indoor environments KW - antimicrobial agents KW - Paints KW - Infants KW - Pollution control KW - A 01450:Environmental Pollution & Waste Treatment KW - Q5 08502:Methods and instruments KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/851465945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+and+Pollution+Research+International&rft.atitle=Testing+antimicrobial+cleaner+efficacy+on+gypsum+wallboard+contaminated+with+Stachybotrys+chartarum&rft.au=Menetrez%2C+Marc+Y%3BFoarde%2C+Karin+K%3BWebber%2C+Tricia+D%3BDean%2C+Timothy+R%3BBetancourt%2C+Doris+A&rft.aulast=Menetrez&rft.aufirst=Marc&rft.date=2007-11-01&rft.volume=14&rft.issue=7&rft.spage=523&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+and+Pollution+Research+International&rft.issn=09441344&rft_id=info:doi/10.1065%2Fespr2007.03.397 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-02-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Relative humidity; Growth; Contamination; Toxicants; Gypsum; Toxicity tests; Borax; Pollution control; Lung; gypsum; Molds; Pollution research; Hemorrhage; Toxins; Infants; Paints; Antimicrobial agents; Plains; Humidity; Construction materials; plains; Indoor environments; antimicrobial agents; Packaging; Stachybotrys chartarum DO - http://dx.doi.org/10.1065/espr2007.03.397 ER - TY - JOUR T1 - Dissolved organic carbon trends resulting from changes in atmospheric deposition chemistry AN - 762682001; 2010-093073 AB - Spatial distribution of DOC trends in data collected from 522 remote lakes and streams in glacial regions of six North European and North American countries is examined, and mechanisms responsible for the distribution are assessed. The relative change in DOC (DOC change per year as a % of the site median) was strongly and inversely related to change in both sulphate concentration and chloride concentration. DOC concentrations have increased in proportion to the rates at which atmospherically deposited anthropogenic S (SO (sub 4) (super -) ) and sea salt (Cl (super -) ) have declined. Increased salt deposition appeared to be critical in explaining the unusual DOC decline in parts of Atlantic Canada. JF - Nature (London) AU - Monteith, Donald T AU - Stoddard, John L AU - Evans, Christopher D AU - de Wit, Heleen A AU - Forsius, Martin AU - Hogasen, Tore AU - Wilander, Anders AU - Skjelkvale, Brit Lisa AU - Jeffries, Dean S AU - Vuorenmaa, Jussi AU - Keller, Bill AU - Kopacek, Jiri AU - Vesely, Josef Y1 - 2007/11// PY - 2007 DA - November 2007 SP - 537 EP - 540 PB - Macmillan Journals, London VL - 450 IS - 7169 SN - 0028-0836, 0028-0836 KW - hydrology KW - North America KW - patterns KW - monitoring KW - surface water KW - rivers and streams KW - lakes KW - atmosphere KW - Europe KW - hydrochemistry KW - dissolved materials KW - deposition KW - carbon KW - organic carbon KW - geochemistry KW - 21:Hydrogeology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762682001?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nature+%28London%29&rft.atitle=Dissolved+organic+carbon+trends+resulting+from+changes+in+atmospheric+deposition+chemistry&rft.au=Monteith%2C+Donald+T%3BStoddard%2C+John+L%3BEvans%2C+Christopher+D%3Bde+Wit%2C+Heleen+A%3BForsius%2C+Martin%3BHogasen%2C+Tore%3BWilander%2C+Anders%3BSkjelkvale%2C+Brit+Lisa%3BJeffries%2C+Dean+S%3BVuorenmaa%2C+Jussi%3BKeller%2C+Bill%3BKopacek%2C+Jiri%3BVesely%2C+Josef&rft.aulast=Monteith&rft.aufirst=Donald&rft.date=2007-11-01&rft.volume=450&rft.issue=7169&rft.spage=537&rft.isbn=&rft.btitle=&rft.title=Nature+%28London%29&rft.issn=00280836&rft_id=info:doi/10.1038%2Fnature06316 L2 - http://www.nature.com/nature/index.html LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from Mineralogical Abstracts, United Kingdom, Twickenham, United Kingdom N1 - Date revised - 2010-01-01 N1 - Number of references - 30 N1 - Document feature - illus. incl. 1 table, sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - atmosphere; carbon; deposition; dissolved materials; Europe; geochemistry; hydrochemistry; hydrology; lakes; monitoring; North America; organic carbon; patterns; rivers and streams; surface water DO - http://dx.doi.org/10.1038/nature06316 ER - TY - JOUR T1 - A review of conflict of interest, competing interest, and bias for toxicologists. AN - 70142224; 18717514 AB - One of the issues often associated with scientific misconduct is conflict of interest. Although there is a lack of uniformity in the definition of conflict of interest, many express concerns that competing interests may bias research methods and the interpretation of data and conclusions. In extreme cases, conflict of interest activity could contribute to scientific misconduct, hinder the training of scientists, delay the dissemination of research results, lead to the harming of human health and the environment, and misdirect society's decisions that rely on science. This article is not a commentary or editorial but an attempt to supply an overview of what has been said, researched, and accomplished in the area of conflict of interest for toxicologists. Discussion of the financial, professional, and philosophical concerns associated with conflict of interest will be followed by brief discussion of general management approaches and the roles of scientists and organizations from all sectors (i.e., academia, industry, non-profit organizations, and government). JF - Toxicology and industrial health AU - Claxton, L D AD - Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. claxton.larry@epa.gov Y1 - 2007/11// PY - 2007 DA - November 2007 SP - 557 EP - 571 VL - 23 IS - 10 SN - 0748-2337, 0748-2337 KW - Index Medicus KW - Biomedical Research KW - Humans KW - Research Support as Topic KW - Conflict of Interest KW - Bias (Epidemiology) KW - Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70142224?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+industrial+health&rft.atitle=A+review+of+conflict+of+interest%2C+competing+interest%2C+and+bias+for+toxicologists.&rft.au=Claxton%2C+L+D&rft.aulast=Claxton&rft.aufirst=L&rft.date=2007-11-01&rft.volume=23&rft.issue=10&rft.spage=557&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+industrial+health&rft.issn=07482337&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-12-16 N1 - Date created - 2008-08-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A method of assessing air toxics concentrations in urban areas using mobile platform measurements. AN - 69049124; 18069452 AB - The objective of this paper is to demonstrate an approach to characterize the spatial variability in ambient air concentrations using mobile platform measurements. This approach may be useful for air toxics assessments in Environmental Justice applications, epidemiological studies, and environmental health risk assessments. In this study, we developed and applied a method to characterize air toxics concentrations in urban areas using results of the recently conducted field study in Wilmington, DE. Mobile measurements were collected over a 4- x 4-km area of downtown Wilmington for three components: formaldehyde (representative of volatile organic compounds and also photochemically reactive pollutants), aerosol size distribution (representing fine particulate matter), and water-soluble hexavalent chromium (representative of toxic metals). These measurements were,used to construct spatial and temporal distributions of air toxics in the area that show a very strong temporal variability, both diurnally and seasonally. An analysis of spatial variability indicates that all pollutants varied significantly by location, which suggests potential impact of local sources. From the comparison with measurements at the central monitoring site, we conclude that formaldehyde and fine particulates show a positive correlation with temperature, which could also be the reason that photochemically generated formaldehyde and fine particulates over the study area correlate well with the fine particulate matter measured at the central site. JF - Journal of the Air & Waste Management Association (1995) AU - Isakov, Vlad AU - Touma, Jawad S AU - Khlystov, Andrey AD - National Oceanic and Atmospheric Administration, Atmospheric Sciences Modeling Division (in Partnership with the U.S. Environmental Protection Agency), Research Triangle Park, NC 27711, USA. Isakov.Vlad@epa.gov Y1 - 2007/11// PY - 2007 DA - November 2007 SP - 1286 EP - 1295 VL - 57 IS - 11 SN - 1096-2247, 1096-2247 KW - Aerosols KW - 0 KW - Particulate Matter KW - Chromium KW - 0R0008Q3JB KW - chromium hexavalent ion KW - 18540-29-9 KW - Formaldehyde KW - 1HG84L3525 KW - Index Medicus KW - Aerosols -- analysis KW - Delaware KW - Chromium -- analysis KW - Particle Size KW - Particulate Matter -- chemistry KW - Particulate Matter -- analysis KW - Formaldehyde -- analysis KW - Cities KW - Air Pollution -- analysis KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69049124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=A+method+of+assessing+air+toxics+concentrations+in+urban+areas+using+mobile+platform+measurements.&rft.au=Isakov%2C+Vlad%3BTouma%2C+Jawad+S%3BKhlystov%2C+Andrey&rft.aulast=Isakov&rft.aufirst=Vlad&rft.date=2007-11-01&rft.volume=57&rft.issue=11&rft.spage=1286&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-17 N1 - Date created - 2007-12-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Relative congener scaling of Polychlorinated dibenzo-p-dioxins and dibenzofurans to estimate building fire contributions in air, surface wipes, and dust samples. AN - 68549833; 18044501 AB - The United States Environmental Protection Agency collected ambient air samples in lower Manhattan for about 9 months following the September 11, 2001 World Trade Center (WTC) attacks. Measurements were made of a host of airborne contaminants including volatile organic compounds, polycyclic aromatic hydrocarbons, asbestos, lead, and other contaminants of concern. The present study focuses on the broad class of polychlorinated dibenzo-p-dioxins (CDDs) and dibenzofurans (CDFs) with specific emphasis on the 17 CDD/CDF congeners that exhibit mammalian toxicity. This work is a statistical study comparing the internal patterns of CDD/CDFs using data from an unambiguous fire event (WTC) and other data sets to help identify their sources. A subset of 29 samples all taken between September 16 and October 31, 2001 were treated as a basis set known to be heavily impacted by the WTC building fire source. A second basis set was created using data from Los Angeles and Oakland, CA as published by the California Air Resources Board (CARB) and treated as the archetypical background pattern for CDD/CDFs. The CARB data had a congener profile appearing similar to background air samples from different locations in America and around the world and in different matrices, such as background soils. Such disparate data would normally be interpreted with a qualitative pattern recognition based on congener bar graphs or other forms of factor or cluster analysis that group similar samples together graphically. The procedure developed here employs aspects of those statistical methods to develop a single continuous output variable per sample. Specifically, a form of variance structure-based cluster analysis is used to group congeners within samples to reduce collinearity in the basis sets, new variables are created based on these groups, and multivariate regression is applied to the reduced variable set to determine a predictive equation. This equation predicts a value for an output variable, OPT: the predicted value of OPT is near zero (0.00) for a background congener profile and near one (1.00) forthe profile characterized by the WTC air profile. Although this empirical method is calibrated with relatively small sets of airborne samples, it is shown to be generalizable to other WTC, fire source, and background air samples as well as other sample matrices including soils, window films and other dust wipes, and bulk dusts. However, given the limited data set examined, the method does not allow further discrimination between the WTC data and the other fire sources. This type of analysis is demonstrated to be useful for complex trace-level data sets with limited data and some below-detection entries. JF - Environmental science & technology AU - Pleil, Joachim D AU - Lorber, Matthew N AD - Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. pleil.joachim@epa.gov Y1 - 2007/11/01/ PY - 2007 DA - 2007 Nov 01 SP - 7286 EP - 7293 VL - 41 IS - 21 SN - 0013-936X, 0013-936X KW - Air Pollutants KW - 0 KW - Benzofurans KW - Dibenzofurans, Polychlorinated KW - Dust KW - Polychlorinated Dibenzodioxins KW - Index Medicus KW - Environmental Monitoring KW - California KW - New York KW - Cluster Analysis KW - September 11 Terrorist Attacks KW - Polychlorinated Dibenzodioxins -- analogs & derivatives KW - Fires KW - Polychlorinated Dibenzodioxins -- analysis KW - Dust -- analysis KW - Air Pollutants -- analysis KW - Benzofurans -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68549833?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Relative+congener+scaling+of+Polychlorinated+dibenzo-p-dioxins+and+dibenzofurans+to+estimate+building+fire+contributions+in+air%2C+surface+wipes%2C+and+dust+samples.&rft.au=Pleil%2C+Joachim+D%3BLorber%2C+Matthew+N&rft.aulast=Pleil&rft.aufirst=Joachim&rft.date=2007-11-01&rft.volume=41&rft.issue=21&rft.spage=7286&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-26 N1 - Date created - 2007-11-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Development of an internal control for evaluation and standardization of a quantitative PCR assay for detection of Helicobacter pylori in drinking water. AN - 68490404; 17905876 AB - Due to metabolic and morphological changes that can prevent Helicobacter pylori cells in water from growing on conventional media, an H. pylori-specific TaqMan quantitative PCR (qPCR) assay was developed that uses a 6-carboxyfluorescein-labeled probe (A. E. McDaniels, L. Wymer, C. Rankin, and R. Haugland, Water Res. 39:4808-4816, 2005). However, proper internal controls are needed to provide an accurate estimate of low numbers of H. pylori in drinking water. In this study, the 135-bp amplicon described by McDaniels et al. was modified at the probe binding region, using PCR mutagenesis. The fragment was incorporated into a single-copy plasmid to serve as a PCR-positive control and cloned into Escherichia coli to serve as a matrix spike. It was shown to have a detection limit of five copies, using a VIC dye-labeled probe. A DNA extraction kit was optimized that allowed sampling of an entire liter of water. Water samples spiked with the recombinant E. coli cells were shown to behave like H. pylori cells in the qPCR assay. The recombinant E. coli cells were optimized to be used at 10 cells/liter of water, where they were shown not to compete with 5 to 3,000 cells of H. pylori in a duplex qPCR assay. Four treated drinking water samples spiked with H. pylori (100 cells) demonstrated similar cycle threshold values if the chlorine disinfectant was first neutralized by sodium thiosulfate. JF - Applied and environmental microbiology AU - Sen, Keya AU - Schable, Nancy A AU - Lye, Dennis J AD - Technical Support Center, Office of Water, U.S. EPA, MLS 140, 26 W ML King Drive, Cincinnati, OH 45268, USA. sen.keya@epa.gov Y1 - 2007/11// PY - 2007 DA - November 2007 SP - 7380 EP - 7387 VL - 73 IS - 22 SN - 0099-2240, 0099-2240 KW - DNA, Bacterial KW - 0 KW - Index Medicus KW - Base Sequence KW - Reproducibility of Results KW - DNA, Bacterial -- isolation & purification KW - DNA, Bacterial -- genetics KW - Reference Standards KW - Molecular Sequence Data KW - Helicobacter pylori -- classification KW - Water Supply -- analysis KW - Water Supply -- standards KW - Polymerase Chain Reaction -- standards KW - Polymerase Chain Reaction -- methods KW - Helicobacter pylori -- genetics KW - Water Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68490404?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Development+of+an+internal+control+for+evaluation+and+standardization+of+a+quantitative+PCR+assay+for+detection+of+Helicobacter+pylori+in+drinking+water.&rft.au=Sen%2C+Keya%3BSchable%2C+Nancy+A%3BLye%2C+Dennis+J&rft.aulast=Sen&rft.aufirst=Keya&rft.date=2007-11-01&rft.volume=73&rft.issue=22&rft.spage=7380&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-11 N1 - Date created - 2007-11-12 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: FEMS Immunol Med Microbiol. 2005 May 1;44(2):157-62 [15866210] Scand J Infect Dis. 1999;31(3):275-9 [10482057] Water Res. 2005 Nov;39(19):4808-16 [16278002] J Appl Microbiol. 1999 Nov;87(5):697-701 [10594710] J Clin Microbiol. 2000 May;38(5):1953-8 [10790127] Epidemiol Rev. 2000;22(2):283-97 [11218379] Microbiol Immunol. 2001;45(7):515-9 [11529557] Appl Environ Microbiol. 2002 Mar;68(3):1436-9 [11872498] Int J Food Microbiol. 2002 Mar 25;74(1-2):37-45 [11929169] Lett Appl Microbiol. 2002;34(6):450-4 [12028428] Appl Environ Microbiol. 2003 Dec;69(12):7462-6 [14660399] Isotopes Environ Health Stud. 2004 Mar;40(1):75-80 [15085986] J Clin Microbiol. 2004 May;42(5):1863-8 [15131141] Lett Appl Microbiol. 2004;39(3):221-5 [15287865] J Clin Microbiol. 2004 Aug;42(8):3613-9 [15297506] J Appl Microbiol. 2004;97(4):690-8 [15357718] Biochem Biophys Res Commun. 1978 Jul 14;83(1):168-71 [212047] Biochem J. 1988 Sep 15;254(3):685-92 [2848494] Lancet. 1991 Jun 22;337(8756):1503-6 [1675369] Scand J Gastroenterol Suppl. 1991;181:58-64 [1866596] J Clin Pathol. 1992 Mar;45(3):228-31 [1556231] Annu Rev Med. 1992;43:135-45 [1580578] J Clin Microbiol. 1992 Sep;30(9):2295-301 [1383268] Appl Environ Microbiol. 1993 Apr;59(4):1231-5 [8489232] Epidemiol Infect. 1993 Dec;111(3):483-90 [8270008] Microbiol Immunol. 1994;38(1):25-30 [8052159] J Clin Microbiol. 1994 Jul;32(7):1663-8 [7929755] J Clin Pathol. 1995 Jul;48(7):662-6 [7560176] Appl Environ Microbiol. 1995 Sep;61(9):3379-84 [7574647] Gastroenterology. 1996 Apr;110(4):1031-5 [8612990] Infect Immun. 1996 Jun;64(6):2331-5 [8675345] J Bacteriol. 1996 Nov;178(21):6145-50 [8892812] Clin Diagn Lab Immunol. 1997 May;4(3):285-90 [9144365] Infect Immun. 1997 Sep;65(9):3672-9 [9284136] Gastroenterology. 1997 Dec;113(6 Suppl):S9-14 [9394753] J Clin Microbiol. 1998 Jan;36(1):191-7 [9431945] Mol Gen Genet. 1998 Mar;257(5):519-28 [9563837] APMIS. 1998 May;106(5):571-9 [9674895] J Appl Microbiol. 1998 Aug;85(2):282-6 [9750301] Mol Microbiol. 1998 Sep;29(5):1137-45 [9767582] Appl Environ Microbiol. 2005 Sep;71(9):5129-37 [16151096] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Nanomaterials and the environment: uses, methods and measurement. AN - 68456276; 17968441 AB - Nanotechnology has emerged as a field of science and engineering which offers many new product possibilities and potential solutions for a variety of problems. Nanomaterials come in many shapes and forms and contribute to potential products that do everything from sense analytes on a molecular level to function as self cleaning surfaces. With new and significant applications, it is likely that nanomaterial containing products may replace many of the products we use on a daily basis, leading to an increased presence of these materials in the environment. This will result in new needs and requirements from detection tools. It is likely that the analytical methods used to monitor nanomaterials in the environment will be very different than those used in risk assessment and exposure studies. This paper briefly outlines the history, impacts, and uses of nanomaterials and discusses possible methods of detection and quantification for environmental samples. The discussions in this article are specific to those matrices relating to wastewaters and sludge. JF - Journal of environmental monitoring : JEM AU - Carl Englert, Brian AD - Environmental Protection Agency, Office of Water, Washington, DC 20460, USA. englert.brian@epa.gov Y1 - 2007/11// PY - 2007 DA - November 2007 SP - 1154 EP - 1161 VL - 9 IS - 11 SN - 1464-0325, 1464-0325 KW - Index Medicus KW - United States KW - United States Food and Drug Administration KW - United States Environmental Protection Agency KW - Particle Size KW - Surface Properties KW - Environmental Monitoring -- methods KW - Nanostructures UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68456276?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+monitoring+%3A+JEM&rft.atitle=Nanomaterials+and+the+environment%3A+uses%2C+methods+and+measurement.&rft.au=Carl+Englert%2C+Brian&rft.aulast=Carl+Englert&rft.aufirst=Brian&rft.date=2007-11-01&rft.volume=9&rft.issue=11&rft.spage=1154&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+monitoring+%3A+JEM&rft.issn=14640325&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-11 N1 - Date created - 2007-10-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - An example of model structure differences using sensitivity analyses in physiologically based pharmacokinetic models of trichloroethylene in humans. AN - 68437748; 17896160 AB - Trichloroethylene (TCE) is an industrial chemical and an environmental contaminant. TCE and its metabolites may be carcinogenic and affect human health. Physiologically based pharmacokinetic (PBPK) models that differ in compartmentalization are developed for TCE metabolism in humans, and the focus of this investigation is to evaluate alternative models. The two models formulated differ in the compartmentalization of metabolites; more specifically, one model has compartments for all chemicals and the other model has only a generalized body compartment for each the metabolites and contains multiple compartments for the parent, TCE. The models are compared through sensitivity analyses in order to selectively discriminate with regards to model structure. Sensitivities to a parameter of cardiac output (Qcc) are calculated, and the more compartmentalized model predictions for excretion show lower sensitivity to changes in this parameter. Values of Qcc used in the sensitivity analyses are specifically chosen to be applicable to adults of ages into the low 60s. Since information about cardiac output across a population is not often incorporated into a PBPK model, the more compartmentalized ("full") model is probably a more appropriate mathematical description of TCE metabolism, but further study may be necessary to decide which model is a more reasonable option if distributional information about Qcc is used. The study is intended to illustrate how sensitivity analysis can be used in order to make appropriate decisions about model development when considering physiological parameters than vary across the population. JF - Bulletin of mathematical biology AU - Yokley, Karen A AU - Evans, Marina V AD - University of North Carolina, Curriculum in Toxicology, Chapel Hill, NC, USA. Yokley.Karen@epamail.epa.gov Y1 - 2007/11// PY - 2007 DA - November 2007 SP - 2591 EP - 2625 VL - 69 IS - 8 SN - 0092-8240, 0092-8240 KW - Carcinogens KW - 0 KW - Trichloroethylene KW - 290YE8AR51 KW - Index Medicus KW - Sensitivity and Specificity KW - Cardiac Output KW - Humans KW - Carcinogens -- pharmacokinetics KW - Mathematics KW - Trichloroethylene -- pharmacokinetics KW - Models, Biological UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68437748?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+mathematical+biology&rft.atitle=An+example+of+model+structure+differences+using+sensitivity+analyses+in+physiologically+based+pharmacokinetic+models+of+trichloroethylene+in+humans.&rft.au=Yokley%2C+Karen+A%3BEvans%2C+Marina+V&rft.aulast=Yokley&rft.aufirst=Karen&rft.date=2007-11-01&rft.volume=69&rft.issue=8&rft.spage=2591&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+mathematical+biology&rft.issn=00928240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-08 N1 - Date created - 2007-10-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - In utero exposure to the environmental androgen trenbolone masculinizes female Sprague-Dawley rats. AN - 68436981; 17931805 AB - Recently, the occurrence of environmental contaminants with androgenic activity has been described from pulp and paper mill effluents and beef feedlot discharges. A synthetic androgen associated with beef production is trenbolone acetate, which is used to promote growth in cattle. A primary metabolite, 17beta Trenbolone (TB), has been characterized as a potent androgen in both in vitro and in vivo studies with rats. The current study was designed to characterize the permanent morphological and functional consequences of prenatal TB exposure on female rats compared with those produced in an earlier study with testosterone propionate (TP). Female rat offspring were exposed to 0mg/day, 0.1mg/day, 0.5mg/day, 1.0mg/day, or 2.0mg/day TB on gestational days 14-19. The 0.5mg/day, 1.0mg/day, or 2.0mg/day TB groups displayed increases in neonatal anogenital distance (AGD) which persisted in the high dose group. Puberty was delayed in the high dose group and there were increased incidences of external genital malformations and the presence of male prostatic tissue in the 0.5mg/day, 1.0mg/day, or 2.0mg/day groups. These changes were associated with amniotic fluid concentrations of TB that compare favorably with concentrations known to be active in both in vitro systems and in fish. JF - Toxicology letters AU - Hotchkiss, A K AU - Furr, J AU - Makynen, E A AU - Ankley, G T AU - Gray, L E AD - Reproductive Toxicology Division, Endocrinology Branch, MD 72, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Y1 - 2007/11/01/ PY - 2007 DA - 2007 Nov 01 SP - 31 EP - 41 VL - 174 IS - 1-3 SN - 0378-4274, 0378-4274 KW - Anabolic Agents KW - 0 KW - Androgens KW - Trenbolone Acetate KW - RUD5Y4SV0S KW - Index Medicus KW - Vagina -- drug effects KW - Rats KW - Maternal-Fetal Exchange KW - Animals KW - Anabolic Agents -- toxicity KW - Rats, Sprague-Dawley KW - Anabolic Agents -- pharmacokinetics KW - Amniotic Fluid -- chemistry KW - Nipples -- drug effects KW - Nipples -- growth & development KW - Vagina -- growth & development KW - Female KW - Pregnancy KW - Trenbolone Acetate -- toxicity KW - Sexual Maturation -- drug effects KW - Trenbolone Acetate -- analogs & derivatives KW - Virilism -- chemically induced KW - Trenbolone Acetate -- pharmacokinetics KW - Androgens -- toxicity KW - Prenatal Exposure Delayed Effects KW - Androgens -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68436981?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+letters&rft.atitle=In+utero+exposure+to+the+environmental+androgen+trenbolone+masculinizes+female+Sprague-Dawley+rats.&rft.au=Hotchkiss%2C+A+K%3BFurr%2C+J%3BMakynen%2C+E+A%3BAnkley%2C+G+T%3BGray%2C+L+E&rft.aulast=Hotchkiss&rft.aufirst=A&rft.date=2007-11-01&rft.volume=174&rft.issue=1-3&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Toxicology+letters&rft.issn=03784274&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-18 N1 - Date created - 2007-10-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Substitution of synthetic chimpanzee androgen receptor for human androgen receptor in competitive binding and transcriptional activation assays for EDC screening. AN - 68432743; 17920789 AB - The potential effect of receptor-mediated endocrine modulators across species is of increasing concern. In attempts to address these concerns, we are developing androgen and estrogen receptor binding assays using recombinant hormone receptors from a number of species across different vertebrate classes. The United States Environmental Protection Agency (USEPA) Office of Science Coordination and Policy (OSCP) requested that we develop a nonhuman mammalian receptor-binding assay for possible use in their Endocrine Disruptor Screening Program (EDSP). Since the chimpanzee androgen receptor is very similar to that of humans and thus possesses properties which could be exploited in future endocrine studies, we synthesized and expressed this gene in eukaryotic expression plasmids, baculovirus expression vectors and replication deficient adenovirus. In all ligand-binding and transcriptional activation assays tested, the chimpanzee receptor performed essentially identically to the human receptor. This suggests that the chimpanzee gene could substitute for the human gene in endocrine screening assays. JF - Toxicology letters AU - Hartig, P C AU - Cardon, M C AU - Lambright, C R AU - Bobseine, K L AU - Gray, L E AU - Wilson, V S AD - Reproductive Toxicology Division, 2525 East Highway 54, MD 72, USEPA, ORD, NHEERL, RTP, NC 27711, United States. hartig.phillip@epa.gov Y1 - 2007/11/01/ PY - 2007 DA - 2007 Nov 01 SP - 89 EP - 97 VL - 174 IS - 1-3 SN - 0378-4274, 0378-4274 KW - AR protein, human KW - 0 KW - Androgens KW - Endocrine Disruptors KW - Receptors, Androgen KW - Recombinant Proteins KW - Metribolone KW - 2C323EGI97 KW - Index Medicus KW - Animals KW - COS Cells KW - Cell Nucleus -- metabolism KW - Humans KW - Transduction, Genetic KW - Biological Assay KW - Metribolone -- metabolism KW - Plasmids KW - Transcriptional Activation KW - Pan troglodytes KW - Adenoviridae -- genetics KW - Baculoviridae -- genetics KW - Genetic Vectors KW - Binding, Competitive KW - Cercopithecus aethiops KW - Androgens -- metabolism KW - Cell Line KW - Recombinant Proteins -- metabolism KW - Receptors, Androgen -- genetics KW - Endocrine Disruptors -- metabolism KW - Receptors, Androgen -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68432743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+letters&rft.atitle=Substitution+of+synthetic+chimpanzee+androgen+receptor+for+human+androgen+receptor+in+competitive+binding+and+transcriptional+activation+assays+for+EDC+screening.&rft.au=Hartig%2C+P+C%3BCardon%2C+M+C%3BLambright%2C+C+R%3BBobseine%2C+K+L%3BGray%2C+L+E%3BWilson%2C+V+S&rft.aulast=Hartig&rft.aufirst=P&rft.date=2007-11-01&rft.volume=174&rft.issue=1-3&rft.spage=89&rft.isbn=&rft.btitle=&rft.title=Toxicology+letters&rft.issn=03784274&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-18 N1 - Date created - 2007-10-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of altered food intake during pubertal development in male and female wistar rats. AN - 68392821; 17728285 AB - The U.S. Environmental Protection Agency is currently validating assays that will be used in a Tier I Screening Battery to detect endocrine disrupting chemicals. A primary concern with the Protocols for the Assessment of Pubertal Development and Thyroid Function in Juvenile Male and Female Rats is that a nonspecific reduction in body weight (BWT) during the exposure period may potentially confound the interpretation of effects on the endocrine endpoints. Wistar rats were underfed 10, 20, 30, or 40% less than the ad libitum food consumed by controls from postnatal days (PNDs) 22 to 42 (females) or PNDs 23 to 53 (males). Terminal BWT of females and males were 2, 4, 12, and 19% and 2, 6, 9, and 19% lower than controls, respectively. In the females, neither the age of pubertal onset nor any of the thyroid hormone endpoints were affected by food restriction (FR) that led to a 12% decrease in BWT. Similarly, none of the male reproductive endpoints examined were altered by FR that led to a 9% BWT decrease. However, decreased triiodothyronine and thyroxin was observed in FR males with a 9% reduced BWT. While these data support the use of the maximum tolerated dose for BWT (10%) for the female protocol, effects on the male thyroid endpoints indicate that a slightly lower limit (25% of ecosystem N or 1,610 kg ha super(-1)). Temporal trends in soil delta super(15)N generally reflected a redistribution of depleted N from the mineral soil to the developing O horizon. Although plants and soil delta super(15)N are coupled over millennial time scales of ecosystem development, our observed divergence between plants and soil suggests that they can be uncoupled during the disturbance-regrowth sequence. The approximate 2ppt decrease in ecosystem delta super(15)N over the century scale suggests significant incorporation of atmospheric N, which was not detected by traditional ecosystem N accounting. Consideration of temporal trends and disturbance legacies can improve our understanding of the influence of broader factors such as climate or N deposition on ecosystem N balances and delta super(15)N. JF - Ecosystems AU - Compton, JE AU - Hooker, T D AU - Perakis, S S AD - U.S. Environmental Protection Agency, NHEERL, Western Ecology Division, 300 SW 35th St, Corvallis, Oregon 97333, USA, compton.jana@epa.gov Y1 - 2007/11// PY - 2007 DA - Nov 2007 SP - 1197 EP - 1208 VL - 10 IS - 7 SN - 1432-9840, 1432-9840 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts; Sustainability Science Abstracts KW - Litter KW - Isotopes KW - Age KW - Pinus strobus KW - Climate KW - Forests KW - Vegetation KW - Soil KW - Agricultural land KW - Terrestrial ecosystems KW - Minerals KW - Nitrogen KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - K 03320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19803430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecosystems&rft.atitle=Ecosystem+N+Distribution+and+delta+super%2815%29N+during+a+Century+of+Forest+Regrowth+after+Agricultural+Abandonment&rft.au=Compton%2C+JE%3BHooker%2C+T+D%3BPerakis%2C+S+S&rft.aulast=Compton&rft.aufirst=JE&rft.date=2007-11-01&rft.volume=10&rft.issue=7&rft.spage=1197&rft.isbn=&rft.btitle=&rft.title=Ecosystems&rft.issn=14329840&rft_id=info:doi/10.1007%2Fs10021-007-9087-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-04-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Soil; Age; Isotopes; Agricultural land; Litter; Terrestrial ecosystems; Climate; Vegetation; Forests; Minerals; Nitrogen; Pinus strobus DO - http://dx.doi.org/10.1007/s10021-007-9087-y ER - TY - JOUR T1 - Transcriptional responses to complex mixtures-A review AN - 19798735; 7939067 AB - Exposure of people to hazardous compounds is primarily through complex environmental mixtures, those that occur through media such as air, soil, water, food, cigarette smoke, and combustion emissions. Microarray technology offers the ability to query the entire genome after exposure to such an array of compounds, permitting a characterization of the biological effects of such exposures. This review summarizes the published literature on the transcriptional profiles resulting from exposure of cells or organisms to complex environmental mixtures such as cigarette smoke, diesel emissions, urban air, motorcycle exhaust, carbon black, jet fuel, and metal ore and fumes. The majority of the mixtures generally up-regulate gene expression, with heme oxygenase 1 and CYP1A1 being up-regulated by all of the mixtures. Most of the mixtures altered the expression of genes involved in oxidative stress response (OH-1, metallothioneins), immune/inflammation response (IL-1b, protein kinase), xenobiotic metabolism (CYP1A1, CYP1B1), coagulation and fibrinolysis (plasminogen activator/inhibitor), proto-oncogenes (FUS1, JUN), heat-shock response (HSP60, HSP70), DNA repair (PCNA, GADD45), structural unit of condensed DNA (Crf15Orf16, DUSP 15), and extracellular matrix degradation (MMP1, 8, 9, 11, 12). Genes involved in aldehyde metabolism, such as ALDH3, appeared to be uniquely modulated by cigarette smoke. Cigarette smoke-exposed populations have been successfully distinguished from control nonexposed populations based on the expression pattern of a subset of genes, thereby demonstrating the utility of this approach in identifying biomarkers of exposure and susceptibility. The analysis of gene-expression data at the pathway and functional level, along with a systems biology approach, will provide a more comprehensive insight into the biological effects of complex mixtures and will improve risk assessment of the same. We suggest critical components of study design and reporting that will achieve this goal. JF - Mutation Research-Reviews in Mutation Research AU - Sen, B AU - Mahadevan, B AU - DeMarini, D M AD - Environmental Carcinogenesis Division, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA, demarini.david@epa.gov Y1 - 2007/11// PY - 2007 DA - Nov 2007 SP - 144 EP - 177 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 636 IS - 1-3 SN - 1383-5742, 1383-5742 KW - Biochemistry Abstracts 2: Nucleic Acids; Genetics Abstracts; Toxicology Abstracts KW - Risk assessment KW - Metallothionein KW - Cigarettes KW - GADD45 protein KW - Fuels KW - Food KW - Interleukin 1 KW - Cigarette smoke KW - DNA microarrays KW - Gene expression KW - Soil KW - Carbon KW - Hsp60 protein KW - plasminogen KW - Proto-oncogenes KW - Metals KW - Data processing KW - Fumes KW - Coagulation KW - Transcription KW - Heme oxygenase (decyclizing) KW - Fibrinolysis KW - biomarkers KW - Exhausts KW - Inflammation KW - Reviews KW - Protein turnover KW - Diesel KW - Cytochrome P450 KW - Metabolism KW - N 14820:DNA Metabolism & Structure KW - G 07710:Chemical Mutagenesis & Radiation KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19798735?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mutation+Research-Reviews+in+Mutation+Research&rft.atitle=Transcriptional+responses+to+complex+mixtures-A+review&rft.au=Sen%2C+B%3BMahadevan%2C+B%3BDeMarini%2C+D+M&rft.aulast=Sen&rft.aufirst=B&rft.date=2007-11-01&rft.volume=636&rft.issue=1-3&rft.spage=144&rft.isbn=&rft.btitle=&rft.title=Mutation+Research-Reviews+in+Mutation+Research&rft.issn=13835742&rft_id=info:doi/10.1016%2Fj.mrrev.2007.08.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Risk assessment; GADD45 protein; Cigarettes; Metallothionein; Food; Fuels; Interleukin 1; Cigarette smoke; DNA microarrays; Soil; Gene expression; Carbon; Hsp60 protein; Proto-oncogenes; plasminogen; Metals; Fumes; Data processing; Coagulation; Transcription; Heme oxygenase (decyclizing); Fibrinolysis; biomarkers; Inflammation; Exhausts; Reviews; Protein turnover; Diesel; Cytochrome P450; Metabolism DO - http://dx.doi.org/10.1016/j.mrrev.2007.08.002 ER - TY - JOUR T1 - Elevated Waves Erode the Western End of the Recently Completed Sand Berm on Dauphin Island, Alabama (U.S.A) AN - 19655900; 8698098 AB - Dauphin island is a microtidal barrier island located approximately 8.0 km offshore from southwestern Alabama (U.S.A.). Morphological changes to the island, brought about by passing tropical storms and hurricanes, have been noted since it was first settled in 1699. On August 29, 2005, Hurricane Katrina (a Category 3 hurricane) made landfall approximately 117 km west of Dauphin Island. Despite the extended distance, the storm impacted the island with waves that completely overwashed and flattened most of the western low-lying areas. The hurricane also segmented Dauphin Island into two distinct barrier islands, the undeveloped Dauphin Island West, and the residentially developed Dauphin Island East. Immediately following the storm, the Town of Dauphin Island recognized the need to take action to protect low-lying residential property on the western segment of Dauphin Island East. Sand berm construction began on January 29, 2007. The 6.4-km-long berm is to provide sufficient time to allow the Town of Dauphin Island to identify and possibly implement a more permanent solution to storm erosion along the low-lying western residential portion of the island before the sand wall will be lost. However, the western end of the sand berm experienced significant erosion due to elevated tides before construction was completed in May 2007. Several segments of the sand berm within this area have been completely lost while other sections are experiencing ongoing erosion. Under these conditions, the Town of Dauphin Island does not have much time to identify and implement one or more long-term solutions to beach erosion and property loss for the western segment of Dauphin Island East. JF - Journal of Coastal Research AU - Froede, Carl R Y1 - 2007/11// PY - 2007 DA - Nov 2007 SP - 1602 EP - 1604 PB - Allen Press, Inc., 810 East Tenth St. VL - 23 IS - 6 SN - 0749-0208, 0749-0208 KW - Sustainability Science Abstracts; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Dauphin Island KW - Hurrican Katrina KW - Storm Waves KW - Sand Berm KW - Eroding Beach KW - Microtidal Barrier Island KW - Coastal research KW - Hurricane landfall KW - Storms KW - Islands KW - Sand KW - Coastal morphology KW - Waves KW - Berms KW - Sedimentation KW - Marine KW - barrier islands KW - Beaches KW - ASW, USA, Alabama, Dauphin I. KW - Construction KW - Beach Erosion KW - Tropical depressions KW - Tides KW - Barrier Islands KW - Hurricanes KW - Erosion KW - towns KW - Barrier islands KW - Beach erosion KW - Q2 09271:Coastal morphology KW - M3 1010:Issues in Sustainable Development KW - O 3050:Sediment Dynamics KW - SW 6010:Structures KW - M2 551.466:Ocean Waves and Tides (551.466) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19655900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Coastal+Research&rft.atitle=Elevated+Waves+Erode+the+Western+End+of+the+Recently+Completed+Sand+Berm+on+Dauphin+Island%2C+Alabama+%28U.S.A%29&rft.au=Froede%2C+Carl+R&rft.aulast=Froede&rft.aufirst=Carl&rft.date=2007-11-01&rft.volume=23&rft.issue=6&rft.spage=1602&rft.isbn=&rft.btitle=&rft.title=Journal+of+Coastal+Research&rft.issn=07490208&rft_id=info:doi/10.2112%2F07A-0019.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Hurricanes; Coastal morphology; Barrier islands; Berms; Sedimentation; Storms; Beach erosion; Tropical depressions; Erosion; Coastal research; Hurricane landfall; barrier islands; Beaches; Islands; Sand; towns; Tides; Construction; Beach Erosion; Waves; Barrier Islands; ASW, USA, Alabama, Dauphin I.; Marine DO - http://dx.doi.org/10.2112/07A-0019.1 ER - TY - CPAPER T1 - Aquifer-Based Ground-Water Management T2 - 2007 Annual Meeting of the Geological Society of America (GSA 2007) AN - 40717803; 4756636 JF - 2007 Annual Meeting of the Geological Society of America (GSA 2007) AU - Wireman, Mike Y1 - 2007/10/28/ PY - 2007 DA - 2007 Oct 28 KW - Ground water KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40717803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Meeting+of+the+Geological+Society+of+America+%28GSA+2007%29&rft.atitle=Aquifer-Based+Ground-Water+Management&rft.au=Wireman%2C+Mike&rft.aulast=Wireman&rft.aufirst=Mike&rft.date=2007-10-28&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Meeting+of+the+Geological+Society+of+America+%28GSA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2007AM/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - What does Geology have to do with It? - Informed Decision Making Regarding Environmental Impacts of Mining T2 - 2007 Annual Meeting of the Geological Society of America (GSA 2007) AN - 40708732; 4756983 JF - 2007 Annual Meeting of the Geological Society of America (GSA 2007) AU - Russell, Carol Cox Y1 - 2007/10/28/ PY - 2007 DA - 2007 Oct 28 KW - Geology KW - Mining KW - Environmental impact KW - Decision making KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40708732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2007+Annual+Meeting+of+the+Geological+Society+of+America+%28GSA+2007%29&rft.atitle=What+does+Geology+have+to+do+with+It%3F+-+Informed+Decision+Making+Regarding+Environmental+Impacts+of+Mining&rft.au=Russell%2C+Carol+Cox&rft.aulast=Russell&rft.aufirst=Carol&rft.date=2007-10-28&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2007+Annual+Meeting+of+the+Geological+Society+of+America+%28GSA+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2007AM/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Studying the effect on system preference by varying coproduct allocation in creating life-cycle inventory. AN - 68488037; 17993161 AB - How one models the input and output data for a life-cycle assessment (LCA) can greatly affect the results. Although much attention has been paid to allocation methodology by researchers in the field, specific guidance is still lacking: Earlier research focused on the effects of applying various allocation schemes to industrial processes when creating life-cycle inventories. To determine the impact of different allocation approaches upon product choice, this study evaluated the gas- and water-phase emissions during the production, distribution, and use of three hypothetical fuel systems (data that represent conventional gasoline and gasoline with 8.7 and 85% ethanol were used as the basis for modeling). This paper presents an explanation of the allocation issue and the results from testing various allocation schemes (weight, volume, market value, energy, and demand-based) when viewed across the entire system. Impact indicators for global warming, ozone depletion, and human health noncancer (water impact) were lower for the ethanol-containing fuels, while impact indicators for acidification, ecotoxicity, eutrophication, human health criteria, and photochemical smog were lower for conventional gasoline (impacts for the water-related human health cancer category showed mixed results). The relative ranking of conventional gasoline in relation to the ethanol-containing fuels was consistent in all instances, suggesting that, in this case study, the choice of allocation methodology had no impact on indicating which fuel has lower environmental impacts. JF - Environmental science & technology AU - Curran, Mary Ann AD - US Environmental Protection Agency, Cincinnati, Ohio 45268, USA. curran.maryann@epa.gov Y1 - 2007/10/15/ PY - 2007 DA - 2007 Oct 15 SP - 7145 EP - 7151 VL - 41 IS - 20 SN - 0013-936X, 0013-936X KW - Environmental Pollutants KW - 0 KW - Petroleum KW - Index Medicus KW - Zea mays KW - Industry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68488037?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Studying+the+effect+on+system+preference+by+varying+coproduct+allocation+in+creating+life-cycle+inventory.&rft.au=Curran%2C+Mary+Ann&rft.aulast=Curran&rft.aufirst=Mary&rft.date=2007-10-15&rft.volume=41&rft.issue=20&rft.spage=7145&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-19 N1 - Date created - 2007-11-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - The Use of Constructed Wetlands for the Treatment of Heavy Metals in Urban Stormwater Runoff T2 - 23rd Annual International Conference on Soils, Sediments and Water AN - 40687368; 4748202 JF - 23rd Annual International Conference on Soils, Sediments and Water AU - Muthukrishnan, Swarna AU - Selvakumar, Ariamalar AU - OConnor, Thomas Y1 - 2007/10/15/ PY - 2007 DA - 2007 Oct 15 KW - Heavy metals KW - Artificial wetlands KW - Stormwater runoff KW - Runoff KW - Wetlands KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40687368?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=23rd+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=The+Use+of+Constructed+Wetlands+for+the+Treatment+of+Heavy+Metals+in+Urban+Stormwater+Runoff&rft.au=Muthukrishnan%2C+Swarna%3BSelvakumar%2C+Ariamalar%3BOConnor%2C+Thomas&rft.aulast=Muthukrishnan&rft.aufirst=Swarna&rft.date=2007-10-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=23rd+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.umasssoils.com/program2007.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Changes to EPAs Spill Prevention, Control, and Countermeasure (SPCC) Program T2 - 23rd Annual International Conference on Soils, Sediments and Water AN - 40685131; 4748303 JF - 23rd Annual International Conference on Soils, Sediments and Water AU - Morash, Melanie Y1 - 2007/10/15/ PY - 2007 DA - 2007 Oct 15 KW - Prevention KW - EPA KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40685131?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=23rd+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Changes+to+EPAs+Spill+Prevention%2C+Control%2C+and+Countermeasure+%28SPCC%29+Program&rft.au=Morash%2C+Melanie&rft.aulast=Morash&rft.aufirst=Melanie&rft.date=2007-10-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=23rd+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.umasssoils.com/program2007.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - US Environmental Protection Agency Response to the Danversport Explosion Site T2 - 23rd Annual International Conference on Soils, Sediments and Water AN - 40683554; 4748304 JF - 23rd Annual International Conference on Soils, Sediments and Water AU - Nalipinski, Mike AU - Bazenas, Ted AU - Wainberg, Dan AU - Young, Catherine AU - Sherrin, Alex Y1 - 2007/10/15/ PY - 2007 DA - 2007 Oct 15 KW - EPA KW - Explosions KW - Environmental protection KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40683554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=23rd+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=US+Environmental+Protection+Agency+Response+to+the+Danversport+Explosion+Site&rft.au=Nalipinski%2C+Mike%3BBazenas%2C+Ted%3BWainberg%2C+Dan%3BYoung%2C+Catherine%3BSherrin%2C+Alex&rft.aulast=Nalipinski&rft.aufirst=Mike&rft.date=2007-10-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=23rd+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.umasssoils.com/program2007.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of MX-treated Salmonella. AN - 70074400; 17925033 AB - Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we describe a general method that can improve microarray analysis of toxicant-exposed cells that uses the intrinsic power of transcriptional coupling and toxicant concentration-expression response data. To illustrate this approach, we characterized changes in global gene expression induced in Salmonella typhimurium TA100 by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), the primary mutagen in chlorinated drinking water. We used the co-expression of genes within an operon and the monotonic increases or decreases in gene expression relative to increasing toxicant concentration to augment our identification of differentially expressed genes beyond Bayesian-t analysis. Operon analysis increased the number of altered genes by 95% from the list identified by a Bayesian t-test of control to the highest concentration of MX. Monotonic analysis added 46% more genes. A functional analysis of the resulting 448 differentially expressed genes yielded functional changes beyond what would be expected from only the mutagenic properties of MX. In addition to gene-expression changes in DNA-damage response, MX induced changes in expression of genes involved in membrane transport and porphyrin metabolism, among other biological processes. The disruption of porphyrin metabolism might be attributable to the structural similarity of MX, which is a chlorinated furanone, to ligands indigenous to the porphyrin metabolism pathway. Interestingly, our results indicate that the lexA regulon in Salmonella, which partially mediates the response to DNA damage, may contain only 60% of the genes present in this regulon in E. coli. In addition, nanH was found to be highly induced by MX and contains a putative lexA regulatory motif in its regulatory region, suggesting that it may be regulated by lexA. Operon and monotonic analyses improved the determination of differentially expressed genes beyond that of Bayesian-t analysis, showing that MX alters cellular metabolism involving pathways other than DNA damage. Because co-expression of similarly functioning genes also occurs in eukaryotes, this method has general applicability for improving analysis of toxicogenomic data. JF - BMC bioinformatics AU - Ward, William O AU - Swartz, Carol D AU - Porwollik, Steffen AU - Warren, Sarah H AU - Hanley, Nancy M AU - Knapp, Geremy W AU - McClelland, Michael AU - DeMarini, David M AD - Environmental Carcinogenesis Division, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. ward.william@epa.gov Y1 - 2007/10/09/ PY - 2007 DA - 2007 Oct 09 SP - 378 VL - 8 KW - Bacterial Proteins KW - 0 KW - Furans KW - Mutagens KW - Transcription Factors KW - 3,4-(dichloro)-5-hydroxy-2(5H)-furanone KW - 766-40-5 KW - Index Medicus KW - Dose-Response Relationship, Drug KW - Operon -- genetics KW - Mutagens -- toxicity KW - Salmonella -- drug effects KW - Bacterial Proteins -- genetics KW - Transcription Factors -- metabolism KW - Bacterial Proteins -- metabolism KW - Furans -- toxicity KW - Salmonella -- metabolism KW - Toxicogenetics -- methods KW - Transcription Factors -- genetics KW - Gene Expression Profiling -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70074400?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+bioinformatics&rft.atitle=Toxicogenomic+analysis+incorporating+operon-transcriptional+coupling+and+toxicant+concentration-expression+response%3A+analysis+of+MX-treated+Salmonella.&rft.au=Ward%2C+William+O%3BSwartz%2C+Carol+D%3BPorwollik%2C+Steffen%3BWarren%2C+Sarah+H%3BHanley%2C+Nancy+M%3BKnapp%2C+Geremy+W%3BMcClelland%2C+Michael%3BDeMarini%2C+David+M&rft.aulast=Ward&rft.aufirst=William&rft.date=2007-10-09&rft.volume=8&rft.issue=&rft.spage=378&rft.isbn=&rft.btitle=&rft.title=BMC+bioinformatics&rft.issn=1471-2105&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-21 N1 - Date created - 2008-02-04 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Mol Microbiol. 2000 Mar;35(6):1560-72 [10760155] Nature. 2004 Dec 16;432(7019):824-8 [15602547] Chem Res Toxicol. 2005 Apr;18(4):619-29 [15833022] Oncogene. 2005 Jun 30;24(28):4572-9 [15824734] Bioinformatics. 2005 Sep 1;21(17):3524-9 [16081476] J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2005;23(2):163-214 [16291527] Environ Mol Mutagen. 2005 Dec;46(4):221-35 [16127667] Environ Mol Mutagen. 2006 Jan;47(1):48-55 [16106442] Mutat Res. 2006 Jan 29;593(1-2):121-42 [16122766] Nucleic Acids Res. 2006;34(2):e8 [16432259] BMC Bioinformatics. 2006;7:19 [16412220] Toxicol Appl Pharmacol. 2006 Apr 15;212(2):146-55 [16122772] BMC Genomics. 2006;7:87 [16630355] Anal Chem. 2006 Sep 15;78(18):6422-32 [16970317] J Bacteriol. 2007 Apr;189(8):3124-32 [17307856] Mutat Res. 1983 May;113(3-4):173-215 [6341825] Mutat Res. 2000 Sep 20;453(1):51-65 [11006412] Mol Cell Biol. 2000 Nov;20(21):8157-67 [11027285] Nucleic Acids Res. 2001 Jan 1;29(1):72-4 [11125053] Bioinformatics. 2001 Jun;17(6):509-19 [11395427] Mutat Res. 2001 Nov 1;483(1-2):1-11 [11600126] Nucleic Acids Res. 2002 Jan 1;30(1):402-4 [11752349] Environ Health Perspect. 2002 Feb;110 Suppl 1:75-87 [11834465] Nucleic Acids Res. 2003 Apr 1;31(7):1869-76 [12655003] Environ Mol Mutagen. 2003;42(1):19-25 [12874809] Science. 2003 Oct 10;302(5643):249-55 [12934013] Bioinformatics. 2003 Nov 22;19(17):2225-36 [14630651] Comput Biol Chem. 2004 Feb;28(1):3-10 [15022635] Bioinformatics. 2004 Jun 12;20(9):1453-4 [14871861] Mutat Res. 1997 Apr 24;390(1-2):171-8 [9150766] Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1486-91 [9990050] Mutat Res. 1999 Apr 26;441(1):145-53 [10224331] J Bacteriol. 2000 Jun;182(12):3490-7 [10852882] N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - Gene Expression Profiling in Aging Rats and Mice Reveals Changes in Xenobiotic Metabolism Genes T2 - 44th Congress of the European Societies of Toxicology AN - 40690348; 4749464 JF - 44th Congress of the European Societies of Toxicology AU - Lee, Janice AU - Wolf, Douglas AU - Allen, James AU - Ward, William AU - Corton, Chris Y1 - 2007/10/07/ PY - 2007 DA - 2007 Oct 07 KW - Aging KW - Metabolism KW - Xenobiotics KW - Mice KW - Rats KW - Gene expression KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40690348?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+Congress+of+the+European+Societies+of+Toxicology&rft.atitle=Gene+Expression+Profiling+in+Aging+Rats+and+Mice+Reveals+Changes+in+Xenobiotic+Metabolism+Genes&rft.au=Lee%2C+Janice%3BWolf%2C+Douglas%3BAllen%2C+James%3BWard%2C+William%3BCorton%2C+Chris&rft.aulast=Lee&rft.aufirst=Janice&rft.date=2007-10-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+Congress+of+the+European+Societies+of+Toxicology&rft.issn=&rft_id=info:doi/ L2 - http://www.eurotox2007.org/downloads/list-of-presentations.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In Vitro Endpoints to Profile Risks Associated with Waste Incineration T2 - 44th Congress of the European Societies of Toxicology AN - 40690032; 4749176 JF - 44th Congress of the European Societies of Toxicology AU - Colacci, Annamaria AU - Vaccari, Monica AU - Silingardi, Paola AU - Horn, Wolfango AU - Mascolo, Maria Grazia AU - Perdichizzi, Stefania AU - Rotondo, Francesca AU - Poluzzi, Vanes AU - Belladonna, Vito AU - Grilli, Sandro Y1 - 2007/10/07/ PY - 2007 DA - 2007 Oct 07 KW - Incineration KW - Wastes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40690032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+Congress+of+the+European+Societies+of+Toxicology&rft.atitle=In+Vitro+Endpoints+to+Profile+Risks+Associated+with+Waste+Incineration&rft.au=Colacci%2C+Annamaria%3BVaccari%2C+Monica%3BSilingardi%2C+Paola%3BHorn%2C+Wolfango%3BMascolo%2C+Maria+Grazia%3BPerdichizzi%2C+Stefania%3BRotondo%2C+Francesca%3BPoluzzi%2C+Vanes%3BBelladonna%2C+Vito%3BGrilli%2C+Sandro&rft.aulast=Colacci&rft.aufirst=Annamaria&rft.date=2007-10-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+Congress+of+the+European+Societies+of+Toxicology&rft.issn=&rft_id=info:doi/ L2 - http://www.eurotox2007.org/downloads/list-of-presentations.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identification of Genes and Pathways Regulated by PPAR- activators using Transcript Profiling: Differences between WY-14,643 and PFOA T2 - 44th Congress of the European Societies of Toxicology AN - 40672714; 4748964 JF - 44th Congress of the European Societies of Toxicology AU - Corton, Chris AU - Rosen, Mitch AU - Ren, Hongzu AU - Vallanat, Beena AU - Abbott, Barbara AU - Lau, Chris Y1 - 2007/10/07/ PY - 2007 DA - 2007 Oct 07 KW - Transcription KW - Profiling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40672714?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+Congress+of+the+European+Societies+of+Toxicology&rft.atitle=Identification+of+Genes+and+Pathways+Regulated+by+PPAR-+activators+using+Transcript+Profiling%3A+Differences+between+WY-14%2C643+and+PFOA&rft.au=Corton%2C+Chris%3BRosen%2C+Mitch%3BRen%2C+Hongzu%3BVallanat%2C+Beena%3BAbbott%2C+Barbara%3BLau%2C+Chris&rft.aulast=Corton&rft.aufirst=Chris&rft.date=2007-10-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+Congress+of+the+European+Societies+of+Toxicology&rft.issn=&rft_id=info:doi/ L2 - http://www.eurotox2007.org/downloads/list-of-presentations.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Changing Paradigm: U.S. EPA's 2005 Guidelines for Cancer Risk Assessment T2 - 44th Congress of the European Societies of Toxicology AN - 40671585; 4748961 JF - 44th Congress of the European Societies of Toxicology AU - Schoeny, Rita Y1 - 2007/10/07/ PY - 2007 DA - 2007 Oct 07 KW - USA KW - Cancer KW - Risk assessment KW - Guidelines KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40671585?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+Congress+of+the+European+Societies+of+Toxicology&rft.atitle=A+Changing+Paradigm%3A+U.S.+EPA%27s+2005+Guidelines+for+Cancer+Risk+Assessment&rft.au=Schoeny%2C+Rita&rft.aulast=Schoeny&rft.aufirst=Rita&rft.date=2007-10-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+Congress+of+the+European+Societies+of+Toxicology&rft.issn=&rft_id=info:doi/ L2 - http://www.eurotox2007.org/downloads/list-of-presentations.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-27 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Microbial sulfate reduction and metal attenuation in pH 4 acid mine water AN - 818638708; 2011-005342 JF - Geochemical Transactions AU - Church, Clinton D AU - Wilkin, Richard T AU - Alpers, Charles N AU - Rye, Robert O AU - McCleskey, R Blaine Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 14 PB - BioMed Central, London VL - 8 IS - 10 SN - 1467-4866, 1467-4866 KW - United States KW - Penn Mine KW - fatty acids KW - lipids KW - copper KW - California KW - anaerobic taxa KW - carboxylic acids KW - cadmium KW - copper ores KW - reduction KW - pH KW - abandoned mines KW - mines KW - sulfate ion KW - acid mine drainage KW - sulfates KW - geomicrobiology KW - oxidation KW - zinc ores KW - pollution KW - hydrogen sulfide KW - organic compounds KW - organic acids KW - biogenic processes KW - nucleic acids KW - metals KW - bacteria KW - metal ores KW - DNA KW - Calaveras County California KW - microorganisms KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/818638708?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Church%2C+Clinton+D%3BWilkin%2C+Richard+T%3BAlpers%2C+Charles+N%3BRye%2C+Robert+O%3BMcCleskey%2C+R+Blaine&rft.aulast=Church&rft.aufirst=Clinton&rft.date=2007-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Microbial+sulfate+reduction+and+metal+attenuation+in+pH+4+acid+mine+water&rft.title=Microbial+sulfate+reduction+and+metal+attenuation+in+pH+4+acid+mine+water&rft.issn=14674866&rft_id=info:doi/10.1186%2F1467-4866-8-10 L2 - http://www.rsc.org/Publishing/Journals/GT/Index.asp LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 75 N1 - Document feature - illus. incl. 4 tables N1 - SuppNotes - Accessed on July 21, 2008 N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - abandoned mines; acid mine drainage; anaerobic taxa; bacteria; biogenic processes; cadmium; Calaveras County California; California; carboxylic acids; copper; copper ores; DNA; fatty acids; geomicrobiology; hydrogen sulfide; lipids; metal ores; metals; microorganisms; mines; nucleic acids; organic acids; organic compounds; oxidation; Penn Mine; pH; pollution; reduction; sulfate ion; sulfates; United States; zinc ores DO - http://dx.doi.org/10.1186/1467-4866-8-10 ER - TY - JOUR T1 - Possible sources of arsenic and its transport mechanism in central Massachusetts AN - 815955374; 2011-001583 AB - A northeasterly trending transect across central Massachusetts, U.S.A., exhibit significantly elevated arsenic levels in its glacial overburden cover. Arsenic data are clustered in the range of 20 to 50 mg/kg although higher values are common occasionally exceeding 500 mg/kg, Ground waters percolating through the overburden (and bedrock as well) show elevated arsenic whenever a reducing environment is encountered, typical values are in the 20 to 500 ppb range or even higher. The uptake mechanism of arsenic by ground water is likely by reductive dissolutions of ferric hydroxide and by a simultaneous release of adsorbed arsenicals. The primary source of arsenic, prior to its sequestration onto ferric hydroxide surfaces in the overburden, is inferred from the multi-elemental correlations of As with Ni, Co, Cu, Zn, Pb, and Mn. Arsenic in the overburden positively correlates with Ni, Mn, and Fe, (Co, Cu, Zn, and Pb were not analyzed). Pond bottom sediments sampled from the area where reducing groundwater discharges into a surface water reservoir are enriched in arsenic (80 to 150 mg/kg) and other metal elements. Correlations with Fe suggest reverse arsenic sequestration by ferric hydroxides at the GW-SW redox interface. Arsenic in the pond bottom sediments positively correlates with Ni, Co, Cu, Zn, and Pb. Zn and Pb are in 100's mg/kg, Cu, Ni, Co are in the 20 to 100 mg/kg range. Higher Zn and Pb values indicate sulfide mineralization which is also supported by field and electron microscope observations. Co, Ni, and As were detected in the bedrock samples as cobaltite-gersdorffite sulfide grains. Whole rock samples of underlying sedimentary and low grade metasedimentary bedrock taken from drill cores have average concentration of Zn and Pb 78 and 51 mg/kg respectively. Concentrations of Ni (73 mg/kg), Co (26 mg/kg), Cu (30 mg/kg) compare with average As of 18 mg/kg. The primary source of arsenic in the central Massachusetts transect appears to be the underlying bedrock, partly mineralized during the low grade regional metamorphism by hydrothermal exhalative processes. JF - Abstracts with Programs - Geological Society of America AU - Hon, Rudolph AU - Brandon, William C AU - Mayo, Matthew AU - Tedder, Newton AU - Anonymous Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 517 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 6 SN - 0016-7592, 0016-7592 KW - United States KW - processes KW - bedrock KW - overburden KW - pollutants KW - arsenic KW - pollution KW - mechanism KW - adsorption KW - solution KW - metasomatism KW - hydrochemistry KW - central Massachusetts KW - transport KW - Massachusetts KW - metals KW - hydrothermal alteration KW - water pollution KW - geochemistry KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/815955374?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Possible+sources+of+arsenic+and+its+transport+mechanism+in+central+Massachusetts&rft.au=Hon%2C+Rudolph%3BBrandon%2C+William+C%3BMayo%2C+Matthew%3BTedder%2C+Newton%3BAnonymous&rft.aulast=Hon&rft.aufirst=Rudolph&rft.date=2007-10-01&rft.volume=39&rft.issue=6&rft.spage=517&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2007 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - adsorption; arsenic; bedrock; central Massachusetts; geochemistry; hydrochemistry; hydrothermal alteration; Massachusetts; mechanism; metals; metasomatism; overburden; pollutants; pollution; processes; solution; transport; United States; water pollution ER - TY - JOUR T1 - Utilizing multiple geophysical techniques to analyze hydrologic controls on riparian meadow complexes in the central Great Basin, NV AN - 815955289; 2011-001601 AB - Riparian meadow systems in the Central Great Basin are of interest because they support the majority of ecosystem diversity in the region. These systems are actively degrading due to incision of the through-going streams, which results in a lowering of the water table and resultant modification of the flora. Bedrock geometry and sediment variability in the meadow complexes are important because of their control on the overall hydrology of the system. We hypothesize that the sediments associated with side-valley alluvial fans and fault-related bedrock steps interact to constrict ground water flow and have a dominant influence on the hydrology. Testing this hypothesis (or alternatives that result from examining the data) is critical in the development of a management plan for protecting and restoring existing meadow complexes. Three geophysical techniques are used in conjunction to analyze the bedrock/sediment interaction involved in the formation of these riparian complexes. Seismic reflection data and seismic refraction tomography data were collected to analyze bedrock structure and topography, while ground penetrating radar (GPR) data were collected to determine the stratigraphic variability. Over 8 kilometers of seismic profiles and over 70 GPR profiles in 6 different riparian meadow complexes were collected over four summers of field work (2003-2006). These data are combined with existing borehole data and field mapping (2007) to ground-truth the geophysical data. These three techniques together are useful because they provide more hydrogeologic information than could be obtained with only one technique. This "data fusion" methodology may also be applied to other geologic and hydrologic settings, such as fluvial or glacial environments. JF - Abstracts with Programs - Geological Society of America AU - Baker, Gregory S AU - Sturtevant, Kristin A AU - Lord, Mark AU - Miller, Jerry AU - Jewett, David AU - Germanoski, Dru AU - Chambers, Jeanne AU - Anonymous Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 520 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 6 SN - 0016-7592, 0016-7592 KW - United States KW - tomography KW - geophysical surveys KW - Basin and Range Province KW - ground-penetrating radar KW - ecosystems KW - refraction methods KW - ground water KW - controls KW - movement KW - glacial environment KW - sediments KW - applications KW - Nevada KW - bedrock KW - North America KW - biodiversity KW - seismic profiles KW - Great Basin KW - geophysical methods KW - radar methods KW - seismic methods KW - geometry KW - riparian environment KW - surveys KW - geophysical profiles KW - fluvial environment KW - central Great Basin KW - 21:Hydrogeology KW - 20:Applied geophysics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/815955289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Utilizing+multiple+geophysical+techniques+to+analyze+hydrologic+controls+on+riparian+meadow+complexes+in+the+central+Great+Basin%2C+NV&rft.au=Baker%2C+Gregory+S%3BSturtevant%2C+Kristin+A%3BLord%2C+Mark%3BMiller%2C+Jerry%3BJewett%2C+David%3BGermanoski%2C+Dru%3BChambers%2C+Jeanne%3BAnonymous&rft.aulast=Baker&rft.aufirst=Gregory&rft.date=2007-10-01&rft.volume=39&rft.issue=6&rft.spage=520&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2007 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - applications; Basin and Range Province; bedrock; biodiversity; central Great Basin; controls; ecosystems; fluvial environment; geometry; geophysical methods; geophysical profiles; geophysical surveys; glacial environment; Great Basin; ground water; ground-penetrating radar; movement; Nevada; North America; radar methods; refraction methods; riparian environment; sediments; seismic methods; seismic profiles; surveys; tomography; United States ER - TY - JOUR T1 - Chlorine inactivation of highly pathogenic avian influenza virus (H5N1). AN - 70083371; 18258010 AB - To determine resistance of highly pathogenic avian influenza (H5N1) virus to chlorination, we exposed allantoic fluid containing 2 virus strains to chlorinated buffer at pH 7 and 8, at 5 degrees C. Free chlorine concentrations typically used in drinking water treatment are sufficient to inactivate the virus by >3 orders of magnitude. JF - Emerging infectious diseases AU - Rice, Eugene W AU - Adcock, Noreen J AU - Sivaganesan, Mano AU - Brown, Justin D AU - Stallknecht, David E AU - Swayne, David E AD - US Environmental Protection Agency, Cincinnati, Ohio 45268, USA. rice.gene@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 1568 EP - 1570 VL - 13 IS - 10 KW - Disinfectants KW - 0 KW - Chlorine KW - 4R7X1O2820 KW - Index Medicus KW - Animals KW - Chickens KW - Halogenation KW - Disinfection -- methods KW - Humans KW - Influenza A Virus, H5N1 Subtype -- drug effects KW - Chlorine -- pharmacology KW - Water Purification -- methods KW - Disinfectants -- pharmacology KW - Virus Inactivation -- drug effects KW - Influenza in Birds -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70083371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Emerging+infectious+diseases&rft.atitle=Chlorine+inactivation+of+highly+pathogenic+avian+influenza+virus+%28H5N1%29.&rft.au=Rice%2C+Eugene+W%3BAdcock%2C+Noreen+J%3BSivaganesan%2C+Mano%3BBrown%2C+Justin+D%3BStallknecht%2C+David+E%3BSwayne%2C+David+E&rft.aulast=Rice&rft.aufirst=Eugene&rft.date=2007-10-01&rft.volume=13&rft.issue=10&rft.spage=1568&rft.isbn=&rft.btitle=&rft.title=Emerging+infectious+diseases&rft.issn=1080-6059&rft_id=info:doi/10.3201%2Feid1310.070323 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-06-25 N1 - Date created - 2008-02-08 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Avian Dis. 1991 Oct-Dec;35(4):974-7 [1838479] Avian Dis. 1993 Jul-Sep;37(3):793-9 [8257373] Emerg Infect Dis. 1999 May-Jun;5(3):461-3 [10341188] Emerg Infect Dis. 2005 Oct;11(10):1515-21 [16318689] Avian Dis. 1990 Apr-Jun;34(2):406-11 [2142420] Emerg Infect Dis. 2006 Nov;12(11):1663-70 [17283615] Avian Dis. 2007 Mar;51(1 Suppl):285-9 [17494568] J Virol. 2004 May;78(9):4892-901 [15078970] Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16936-41 [17075062] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3201/eid1310.070323 ER - TY - JOUR T1 - Assessment of inhalation exposures and potential health risks to the general population that resulted from the collapse of the World Trade Center towers. AN - 69057936; 18076491 AB - In the days following the collapse of the World Trade Center (WTC) towers on September 11, 2001 (9/11), the U.S. Environmental Protection Agency (EPA) initiated numerous air monitoring activities to better understand the ongoing impact of emissions from that disaster. Using these data, EPA conducted an inhalation exposure and human health risk assessment to the general population. This assessment does not address exposures and potential impacts that could have occurred to rescue workers, firefighters, and other site workers, nor does it address exposures that could have occurred in the indoor environment. Contaminants evaluated include particulate matter (PM), metals, polychlorinated biphenyls, dioxins, asbestos, volatile organic compounds, particle-bound polycyclic aromatic hydrocarbons, silica, and synthetic vitreous fibers (SVFs). This evaluation yielded three principal findings. (1) Persons exposed to extremely high levels of ambient PM and its components, SVFs, and other contaminants during the collapse of the WTC towers, and for several hours afterward, were likely to be at risk for acute and potentially chronic respiratory effects. (2) Available data suggest that contaminant concentrations within and near ground zero (GZ) remained significantly elevated above background levels for a few days after 9/11. Because only limited data on these critical few days were available, exposures and potential health impacts could not be evaluated with certainty for this time period. (3) Except for inhalation exposures that may have occurred on 9/11 and a few days afterward, the ambient air concentration data suggest that persons in the general population were unlikely to suffer short-term or long-term adverse health effects caused by inhalation exposures. While this analysis by EPA evaluated the potential for health impacts based on measured air concentrations, epidemiological studies conducted by organizations other than EPA have attempted to identify actual impacts. Such studies have identified respiratory effects in worker and general populations, and developmental effects in newborns whose mothers were near GZ on 9/11 or shortly thereafter. While researchers are not able to identify specific times and even exactly which contaminants are the cause of these effects, they have nonetheless concluded that exposure to WTC contaminants (and/or maternal stress, in the case of developmental effects) resulted in these effects, and have identified the time period including 9/11 itself and the days and few weeks afterward as a period of most concern based on high concentrations of key pollutants in the air and dust. JF - Risk analysis : an official publication of the Society for Risk Analysis AU - Lorber, Matthew AU - Gibb, Herman AU - Grant, Lester AU - Pinto, Joseph AU - Pleil, Joachim AU - Cleverly, David AD - National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., Washington, DC 22314, USA. lorber.mathew@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 1203 EP - 1221 VL - 27 IS - 5 SN - 0272-4332, 0272-4332 KW - Air Pollutants KW - 0 KW - Dioxins KW - Furans KW - Metals, Heavy KW - Polycyclic Aromatic Hydrocarbons KW - Asbestos KW - 1332-21-4 KW - Silicon Dioxide KW - 7631-86-9 KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - United States KW - Asbestos -- analysis KW - Dioxins -- adverse effects KW - Inhalation KW - United States Environmental Protection Agency KW - Silicon Dioxide -- analysis KW - Dioxins -- analysis KW - Humans KW - Environmental Exposure -- analysis KW - Volatilization KW - Polycyclic Aromatic Hydrocarbons -- adverse effects KW - Polychlorinated Biphenyls -- analysis KW - Silicon Dioxide -- adverse effects KW - Risk Assessment KW - Polychlorinated Biphenyls -- adverse effects KW - Metals, Heavy -- analysis KW - Furans -- analysis KW - Metals, Heavy -- adverse effects KW - Environmental Monitoring KW - New York City KW - Public Health KW - Furans -- adverse effects KW - Polycyclic Aromatic Hydrocarbons -- analysis KW - Asbestos -- adverse effects KW - Environmental Exposure -- adverse effects KW - Air Pollutants -- analysis KW - Air Pollutants -- adverse effects KW - September 11 Terrorist Attacks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69057936?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.atitle=Assessment+of+inhalation+exposures+and+potential+health+risks+to+the+general+population+that+resulted+from+the+collapse+of+the+World+Trade+Center+towers.&rft.au=Lorber%2C+Matthew%3BGibb%2C+Herman%3BGrant%2C+Lester%3BPinto%2C+Joseph%3BPleil%2C+Joachim%3BCleverly%2C+David&rft.aulast=Lorber&rft.aufirst=Matthew&rft.date=2007-10-01&rft.volume=27&rft.issue=5&rft.spage=1203&rft.isbn=&rft.btitle=&rft.title=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.issn=02724332&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-27 N1 - Date created - 2007-12-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Uncertainties in the CIIT model for formaldehyde-induced carcinogenicity in the rat: a limited sensitivity analysis-I. AN - 69057567; 18076493 AB - Scientists at the CIIT Centers for Health Research (Conolly et al., 2000, 2003; Kimbell et al., 2001a, 2001b) developed a two-stage clonal expansion model of formaldehyde-induced nasal cancers in the F344 rat that made extensive use of mechanistic information. An inference of their modeling approach was that formaldehyde-induced tumorigenicity could be optimally explained without the role of formaldehyde's mutagenic action. In this article, we examine the strength of this result and modify select features to examine the sensitivity of the predicted dose response to select assumptions. We implement solutions to the two-stage cancer model that are valid for nonhomogeneous models (i.e., models with time-dependent parameters), thus accounting for time dependence in variables. In this reimplementation, we examine the sensitivity of model predictions to pooling historical and concurrent control data, and to lumping sacrificed animals in which tumors were discovered incidentally with those in which death was caused by the tumors. We found the CIIT model results were not significantly altered with the nonhomogeneous solutions. Dose-response predictions below the range of exposures where tumors occurred in the bioassays were highly sensitive to the choice of control data. In the range of exposures where tumors were observed, the model attributed up to 74% of the added tumor probability to formaldehyde's mutagenic action when our reanalysis restricted the use of the National Toxicology Program (NTP) historical control data to only those obtained from inhalation exposures. Model results were insensitive to hourly or daily temporal variations in DNA protein cross-link (DPX) concentration, a surrogate for the dose-metric linked to formaldehyde-induced mutations, prompting us to utilize weekly averages for this quantity. Various other biological and mathematical uncertainties in the model have been retained unmodified in this analysis. These include model specification of initiated cell division and death rates, and uncertainty and variability in the dose response for cell replication rates, issues that will be considered in a future paper. JF - Risk analysis : an official publication of the Society for Risk Analysis AU - Subramaniam, Ravi P AU - Crump, Kenny S AU - Van Landingham, Cynthia AU - White, Paul AU - Chen, Chao AU - Schlosser, Paul M AD - NCEA, ORD, U.S. Environmental Protection Agency, Washington, DC 20460, USA. Subramaniam.Ravi@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 1237 EP - 1254 VL - 27 IS - 5 SN - 0272-4332, 0272-4332 KW - Carcinogens KW - 0 KW - Cross-Linking Reagents KW - Mutagens KW - Formaldehyde KW - 1HG84L3525 KW - Index Medicus KW - Sensitivity and Specificity KW - Animals KW - Probability KW - Cocarcinogenesis KW - DNA Damage KW - Cross-Linking Reagents -- toxicity KW - Carcinoma, Squamous Cell -- chemically induced KW - Mutagens -- toxicity KW - Likelihood Functions KW - Models, Biological KW - Rats KW - Uncertainty KW - Rats, Inbred F344 KW - Carcinoma, Squamous Cell -- pathology KW - Cell Division KW - Nose Neoplasms -- pathology KW - Nose Neoplasms -- chemically induced KW - Carcinogens -- toxicity KW - Formaldehyde -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/69057567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.atitle=Uncertainties+in+the+CIIT+model+for+formaldehyde-induced+carcinogenicity+in+the+rat%3A+a+limited+sensitivity+analysis-I.&rft.au=Subramaniam%2C+Ravi+P%3BCrump%2C+Kenny+S%3BVan+Landingham%2C+Cynthia%3BWhite%2C+Paul%3BChen%2C+Chao%3BSchlosser%2C+Paul+M&rft.aulast=Subramaniam&rft.aufirst=Ravi&rft.date=2007-10-01&rft.volume=27&rft.issue=5&rft.spage=1237&rft.isbn=&rft.btitle=&rft.title=Risk+analysis+%3A+an+official+publication+of+the+Society+for+Risk+Analysis&rft.issn=02724332&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-02-27 N1 - Date created - 2007-12-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - U.S. EPA's Community Action for a Renewed Environment Program and collaboration with CDC/ATSDR. AN - 68410225; 17941404 JF - Journal of environmental health AU - Topper, Henry AD - Community Action for a Renewed Environment Program, Office of Pollution Prevention and Toxic Substances, U.S. Environment Protection Agency, Washington, DC 20460, USA. topper.henry@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 56 EP - 57 VL - 70 IS - 3 SN - 0022-0892, 0022-0892 KW - Index Medicus KW - United States KW - Cooperative Behavior KW - United States Environmental Protection Agency KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Environmental Health KW - Government Programs KW - Community Participation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68410225?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+health&rft.atitle=U.S.+EPA%27s+Community+Action+for+a+Renewed+Environment+Program+and+collaboration+with+CDC%2FATSDR.&rft.au=Topper%2C+Henry&rft.aulast=Topper&rft.aufirst=Henry&rft.date=2007-10-01&rft.volume=70&rft.issue=3&rft.spage=56&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+health&rft.issn=00220892&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-15 N1 - Date created - 2007-10-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Nanotechnology applications and implications research supported by the US Environmental Protection Agency STAR grants program. AN - 68336553; 17909637 AB - Since 2002, the US Environmental Protection Agency (EPA) has been funding research on the environmental aspects of nanotechnology through its Science to Achieve Results (STAR) grants program. In total, more than $25 million has been awarded for 86 research projects on the environmental applications and implications of nanotechnology. In the applications area, grantees have produced promising results in green manufacturing, remediation, sensors, and treatment using nanotechnology and nanomaterials. Although there are many potential benefits of nanotechnology, there has also been increasing concern about the environmental and health effects of nanomaterials, and there are significant gaps in the data needed to address these concerns. Research performed by STAR grantees is beginning to address these needs. JF - Journal of environmental monitoring : JEM AU - Savage, Nora AU - Thomas, Treye A AU - Duncan, Jeremiah S AD - Environmental Engineer, Office of Research and Development, US Environmental Protection Agency, 1200 Pennsylvania Ave, NW, MC 8722F, Washington DC, 20460, USA. savage.nora@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 1046 EP - 1054 VL - 9 IS - 10 SN - 1464-0325, 1464-0325 KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - United States KW - Humans KW - Environmental Exposure KW - Nanostructures KW - Nanotechnology -- economics KW - United States Environmental Protection Agency -- economics KW - Research Support as Topic -- economics KW - Financing, Government -- economics KW - Research Support as Topic -- trends KW - Nanotechnology -- trends KW - Financing, Organized -- economics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68336553?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+monitoring+%3A+JEM&rft.atitle=Nanotechnology+applications+and+implications+research+supported+by+the+US+Environmental+Protection+Agency+STAR+grants+program.&rft.au=Savage%2C+Nora%3BThomas%2C+Treye+A%3BDuncan%2C+Jeremiah+S&rft.aulast=Savage&rft.aufirst=Nora&rft.date=2007-10-01&rft.volume=9&rft.issue=10&rft.spage=1046&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+monitoring+%3A+JEM&rft.issn=14640325&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-25 N1 - Date created - 2007-10-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Raman spectroscopy-based metabolomics for differentiating exposures to triazole fungicides using rat urine. AN - 68325857; 17718537 AB - Normal Raman spectroscopy was evaluated as a metabolomic tool for assessing the impacts of exposure to environmental contaminants, using rat urine collected during the course of a toxicological study. Specifically, one of three triazole fungicides, myclobutanil, propiconazole, or triadimefon, was administered daily via oral gavage to male Sprague-Dawley rats at doses of 300, 300, or 175 mg/kg, respectively. Urine was collected from all three treatment groups and also from vehicle control rats on day six, following five consecutive days of exposure. Spectra were acquired with a CCD-based dispersive Raman spectrometer, using 785-nm diode laser excitation. To optimize the signal-to-noise ratio, urine samples were filtered through a stirred ultrafiltration cell with a 500 nominal molecular weight limit filter to remove large, unwanted urine components that can degrade the spectrum via fluorescence. However, a subsequent investigation suggested that suitable spectra can be obtained in a high-throughput fashion, with little or no Raman-specific sample preparation. For the sake of comparison, a parallel 1H NMR-based metabolomic analysis was also conducted on the unfiltered samples. Results from multivariate data analysis demonstrated that the Raman method compares favorably with NMR in regard to the ability to differentiate responses from these three contaminants. JF - Analytical chemistry AU - Cherney, Daniel P AU - Ekman, Drew R AU - Dix, David J AU - Collette, Timothy W AD - U.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Athens, Georgia 30605, USA. Y1 - 2007/10/01/ PY - 2007 DA - 2007 Oct 01 SP - 7324 EP - 7332 VL - 79 IS - 19 SN - 0003-2700, 0003-2700 KW - Fungicides, Industrial KW - 0 KW - Triazoles KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Filtration KW - Spectrometry, Fluorescence KW - Male KW - Magnetic Resonance Spectroscopy KW - Fungicides, Industrial -- urine KW - Triazoles -- urine KW - Spectrum Analysis, Raman -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68325857?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Raman+spectroscopy-based+metabolomics+for+differentiating+exposures+to+triazole+fungicides+using+rat+urine.&rft.au=Cherney%2C+Daniel+P%3BEkman%2C+Drew+R%3BDix%2C+David+J%3BCollette%2C+Timothy+W&rft.aulast=Cherney&rft.aufirst=Daniel&rft.date=2007-10-01&rft.volume=79&rft.issue=19&rft.spage=7324&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=00032700&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-07 N1 - Date created - 2007-09-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Acute toluene exposure and rat visual function in proportion to momentary brain concentration. AN - 68294033; 17623699 AB - Acute exposure to toluene was assessed in two experiments to determine the relationship between brain toluene concentration and changes in neurophysiological function. The concentration of toluene in brain tissue at the time of assessment was estimated using a physiologically based pharmacokinetic model. Brain neurophysiological function was measured using pattern-elicited visual evoked potentials (VEP) recorded from electrodes located over visual cortex of adult male Long-Evans rats. In the first experiment, VEPs were recorded before and during exposure to control air or toluene at 1000 ppm for 4 h, 2000 ppm for 2 h, 3000 ppm for 1.3 h, or 4000 ppm for 1 h. In the second experiment, VEPs were recorded during and after exposure to clean air or 3000 or 4000 ppm toluene. In both experiments, the response amplitude of the major spectral component of the VEP (F2 at twice the stimulus rate in steady-state responses) was reduced by toluene. A logistic function was fit to baseline-adjusted F2 amplitudes from the first experiment that described a significant relationship between brain toluene concentration and VEP amplitude deficits. In the second experiment, 3000 ppm caused equivalent VEP deficits during or after exposure as a function of estimated brain concentration, but 4000 ppm showed a rapid partial adaptation to the acute effects of toluene after exposure. In general, however, the neurophysiological deficits caused by acute toluene exposure could be described by estimates of the momentary concentration of toluene in the brain at the time of VEP evaluation. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Boyes, William K AU - Bercegeay, Mark AU - Krantz, Quentin Todd AU - Kenyon, Elaina M AU - Bale, Ambuja S AU - Shafer, Timothy J AU - Bushnell, Philip J AU - Benignus, Vernon A AD - Neurotoxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. boyes.william@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 572 EP - 581 VL - 99 IS - 2 SN - 1096-6080, 1096-6080 KW - Trichloroethylene KW - 290YE8AR51 KW - Toluene KW - 3FPU23BG52 KW - Index Medicus KW - Rats KW - Animals KW - Rats, Long-Evans KW - Models, Biological KW - Trichloroethylene -- toxicity KW - Male KW - Evoked Potentials, Visual -- drug effects KW - Toluene -- pharmacokinetics KW - Brain -- metabolism KW - Toluene -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68294033?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Acute+toluene+exposure+and+rat+visual+function+in+proportion+to+momentary+brain+concentration.&rft.au=Boyes%2C+William+K%3BBercegeay%2C+Mark%3BKrantz%2C+Quentin+Todd%3BKenyon%2C+Elaina+M%3BBale%2C+Ambuja+S%3BShafer%2C+Timothy+J%3BBushnell%2C+Philip+J%3BBenignus%2C+Vernon+A&rft.aulast=Boyes&rft.aufirst=William&rft.date=2007-10-01&rft.volume=99&rft.issue=2&rft.spage=572&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-11-29 N1 - Date created - 2007-09-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Perfluoroalkyl acids: a review of monitoring and toxicological findings. AN - 68292222; 17519394 AB - In recent years, human and wildlife monitoring studies have identified perfluoroalkyl acids (PFAA) worldwide. This has led to efforts to better understand the hazards that may be inherent in these compounds, as well as the global distribution of the PFAAs. Much attention has focused on understanding the toxicology of the two most widely known PFAAs, perfluorooctanoic acid, and perfluorooctane sulfate. More recently, research was extended to other PFAAs. There has been substantial progress in understanding additional aspects of the toxicology of these compounds, particularly related to the developmental toxicity, immunotoxicity, hepatotoxicity, and the potential modes of action. This review provides an overview of the recent advances in the toxicology and mode of action for PFAAs, and of the monitoring data now available for the environment, wildlife, and humans. Several avenues of research are proposed that would further our understanding of this class of compounds. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Lau, Christopher AU - Anitole, Katherine AU - Hodes, Colette AU - Lai, David AU - Pfahles-Hutchens, Andrea AU - Seed, Jennifer AD - Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 366 EP - 394 VL - 99 IS - 2 SN - 1096-6080, 1096-6080 KW - Fluorocarbons KW - 0 KW - Hormones KW - Index Medicus KW - Animals KW - Immune System -- drug effects KW - Fetus -- drug effects KW - Liver -- drug effects KW - Humans KW - Hormones -- blood KW - Abnormalities, Drug-Induced -- etiology KW - Male KW - Female KW - Fluorocarbons -- analysis KW - Fluorocarbons -- toxicity KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68292222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Perfluoroalkyl+acids%3A+a+review+of+monitoring+and+toxicological+findings.&rft.au=Lau%2C+Christopher%3BAnitole%2C+Katherine%3BHodes%2C+Colette%3BLai%2C+David%3BPfahles-Hutchens%2C+Andrea%3BSeed%2C+Jennifer&rft.aulast=Lau&rft.aufirst=Christopher&rft.date=2007-10-01&rft.volume=99&rft.issue=2&rft.spage=366&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-11-29 N1 - Date created - 2007-09-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Disposition of bromodichloromethane in humans following oral and dermal exposure. AN - 68289681; 17656487 AB - Exposure to bromodichloromethane (BDCM), one of the most prevalent disinfection byproducts in drinking water, can occur via ingestion of water and by dermal absorption and inhalation during activities such as bathing and showering. The objectives of this research were to assess BDCM pharmacokinetics in human volunteers exposed percutaneously and orally to (13)C-BDCM and to evaluate factors that could affect disposition of BDCM. Among study subjects, CYP2E1 activity varied fourfold; 20% had the glutathione S-transferase theta 1-1 homozygous null genotype; and body fat ranged from 7 to 22%. Subjects were exposed to (13)C-BDCM in water (target concentration of 36 mug/l) via ingestion and by forearm submersion. Blood was collected for up to 24 h and analyzed for (13)C-BDCM by solid-phase microextraction and high-resolution GC-MS. Urine was collected before and after exposure for mutagenicity determinations in Salmonella. After ingestion (mean dose = 146 ng/kg), blood (13)C-BDCM concentrations peaked and declined rapidly, returning to levels near or below the limit of detection (LOD) within 4 h. The T(max) for the oral exposure ranged from 5 to 30 min, and the C(max) ranged from 0.4 to 4.1 ng/l. After the 1 h dermal exposure (estimated mean dose = 155 ng/kg), blood concentrations of (13)C-BDCM ranged from 39 to 170 ng/l and decreased to levels near or below the LOD by 24 h. Peak postdose urine mutagenicity levels that were at least twice that of the predose mean level occurred in 6 of 10 percutaneously exposed subjects and 3 of 8 orally exposed subjects. These results demonstrate a highly significant contribution of dermal absorption to circulating levels of BDCM and confirm the much lower oral contribution, indicating that water uses involving dermal contact can lead to much greater systemic BDCM doses than water ingestion. These data will facilitate development and validation of physiologically based pharmacokinetic models for BDCM in humans. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Leavens, Teresa L AU - Blount, Benjamin C AU - DeMarini, David M AU - Madden, Michael C AU - Valentine, John L AU - Case, Martin W AU - Silva, Lalith K AU - Warren, Sarah H AU - Hanley, Nancy M AU - Pegram, Rex A AD - U.S. EPA, Office of Research and Development (ORD), National Health and Environmental Effects Research Laboratory (NHEERL), Human Studies Division, Chapel Hill, North Carolina 27599, USA. Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 432 EP - 445 VL - 99 IS - 2 SN - 1096-6080, 1096-6080 KW - Trihalomethanes KW - 0 KW - bromodichloromethane KW - 7LN464CH2O KW - Cytochrome P-450 CYP2E1 KW - EC 1.14.13.- KW - Glutathione Transferase KW - EC 2.5.1.18 KW - glutathione transferase T1-1, human KW - Index Medicus KW - Administration, Oral KW - Trihalomethanes -- pharmacokinetics KW - Glutathione Transferase -- physiology KW - Administration, Cutaneous KW - Half-Life KW - Area Under Curve KW - Humans KW - Cytochrome P-450 CYP2E1 -- physiology KW - Models, Biological KW - Trihalomethanes -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68289681?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Disposition+of+bromodichloromethane+in+humans+following+oral+and+dermal+exposure.&rft.au=Leavens%2C+Teresa+L%3BBlount%2C+Benjamin+C%3BDeMarini%2C+David+M%3BMadden%2C+Michael+C%3BValentine%2C+John+L%3BCase%2C+Martin+W%3BSilva%2C+Lalith+K%3BWarren%2C+Sarah+H%3BHanley%2C+Nancy+M%3BPegram%2C+Rex+A&rft.aulast=Leavens&rft.aufirst=Teresa&rft.date=2007-10-01&rft.volume=99&rft.issue=2&rft.spage=432&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-11-29 N1 - Date created - 2007-09-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Identification of dioxin and dioxin-like polychlorbiphenyls in plant tissues and contaminated soils. AN - 68262452; 17482350 AB - The environmental analysis laboratory (EAL) of the Taiwan environmental protection administration (TEPA) has been monitoring certain sites polluted in southern Taiwan by pentachlorophenol manufacture. The analytical results revealed peculiarities in the concentration distributions in plant tissues. There are no available data on dioxin and dioxin-like polychlorbiphenyls (DL-PCBs), which can be taken up from contaminated soils by plant tissues. Thus, the aims of this study were to identify, understand, and to validate these dioxin and DL-PCBs concentrations in plant tissues of the contaminated soils. This research analyzed ten species of plant tissues, including tappa (Boussonetia papyrifera) and common jasmin orange (Murraya paniculata) from sites in southern Taiwan, with different levels of contamination. Dioxin concentrations in these plant tissues ranged from 12.7 to 2919 ng WHO-TEQ(DF)/kg dry weight (d.w.), with average of 463 ng WHO-TEQ(DF)/kg d.w. (n=16). The DL-PCBs concentrations ranged from 0.236 to 1.75 ng WHO-TEQp/kg d.w., with an average of 0.605 ng WHO-TEQp/kg d.w. (n=8). Tappa is one of the most common and fastest growing plants in Taiwan. It also shows the highest tolerance to environmental contaminants and accumulates dioxin and DL-PCBs. This is one of the best species to take up dioxins and DL-PCBs effectively. It can be recommended as a candidate for dioxin and DL-PCB phyto-remediation. These data are useful to evaluate bioaccumulation of dioxin and DL-PCBs, and to study the capability of phyto-remediation in contaminated soils. JF - Journal of hazardous materials AU - Jou, Jin-Juh AU - Chung, Jen-Chir AU - Weng, Ying-Ming AU - Liaw, Shu-Liang AU - Wang, Ming Kuang AD - Environmental Engineering Graduate School, National Central University and Environmental Analysis Laboratory, EPA, Taiwan, ROC. jjjou@mail.niea.gov.tw Y1 - 2007/10/01/ PY - 2007 DA - 2007 Oct 01 SP - 174 EP - 179 VL - 149 IS - 1 SN - 0304-3894, 0304-3894 KW - Benzofurans KW - 0 KW - Dibenzofurans, Polychlorinated KW - Polychlorinated Dibenzodioxins KW - Soil Pollutants KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - Plant Leaves -- metabolism KW - Plant Stems -- metabolism KW - Biodegradation, Environmental KW - Plant Roots -- metabolism KW - Polychlorinated Dibenzodioxins -- analogs & derivatives KW - Plants -- metabolism KW - Soil Pollutants -- metabolism KW - Polychlorinated Biphenyls -- metabolism KW - Polychlorinated Dibenzodioxins -- metabolism KW - Benzofurans -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68262452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+hazardous+materials&rft.atitle=Identification+of+dioxin+and+dioxin-like+polychlorbiphenyls+in+plant+tissues+and+contaminated+soils.&rft.au=Jou%2C+Jin-Juh%3BChung%2C+Jen-Chir%3BWeng%2C+Ying-Ming%3BLiaw%2C+Shu-Liang%3BWang%2C+Ming+Kuang&rft.aulast=Jou&rft.aufirst=Jin-Juh&rft.date=2007-10-01&rft.volume=149&rft.issue=1&rft.spage=174&rft.isbn=&rft.btitle=&rft.title=Journal+of+hazardous+materials&rft.issn=03043894&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-10 N1 - Date created - 2007-09-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The ecological condition of Veracruz, Mexico estuaries. AN - 68255145; 17295108 AB - During June and July, 2002, forty-seven stations were sampled within estuaries along the gulf coast of the state of Veracruz, MX, using a probabilistic survey design and a common set of response indicators. The objective of the study was to collect information to assess the condition of estuarine waters within the state of Veracruz, and to provide data that would strengthen future assessments of Gulf of Mexico estuaries. Samples for water quality, sediment contaminants, sediment toxicity, and benthic populations were collected in a manner consistent with EPA's National Coastal Assessment (NCA). Data were evaluated by comparing indicator measurements to tropical waters threshold values cited in US EPA's National Coastal Condition Report II, 2004, for tropical waters. In Veracruz, 75% of the area sampled rated poor for water quality, attributed primarily to high concentrations reported for chlorophyll a, and dissolved nutrients. One percent of the area exhibited poor sediment quality, based on PAH and metals concentrations. Compared to US estuaries of the Gulf of Mexico, water quality observed in Veracruz estuaries was more affected by nutrient over-enrichment. The probabilitistic nature of the survey design allowed for the comparison of the condition of Veracruz and the US GOM estuaries. JF - Environmental monitoring and assessment AU - Macauley, J M AU - Harwell, L C AU - Alafita, H V AD - Gulf Ecology Division, U.S. EPA, National Health and Environmental Effects Research Laboratory, Gulf Breeze, FL 32561, USA. macauley.john@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 177 EP - 185 VL - 133 IS - 1-3 SN - 0167-6369, 0167-6369 KW - Water KW - 059QF0KO0R KW - Index Medicus KW - Mexico KW - Geologic Sediments KW - Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68255145?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+monitoring+and+assessment&rft.atitle=The+ecological+condition+of+Veracruz%2C+Mexico+estuaries.&rft.au=Macauley%2C+J+M%3BHarwell%2C+L+C%3BAlafita%2C+H+V&rft.aulast=Macauley&rft.aufirst=J&rft.date=2007-10-01&rft.volume=133&rft.issue=1-3&rft.spage=177&rft.isbn=&rft.btitle=&rft.title=Environmental+monitoring+and+assessment&rft.issn=01676369&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-19 N1 - Date created - 2007-09-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Rejoinder: How EPA Research, Policies, and Programs Can Advance Urban Sustainability AN - 61669360; 200822104 AB - The authors, Hecht and Sanders, provide a rejoinder to comments about their article, "How EPA research, policies, and programs can advance urban sustainability.". JF - Sustainability: Science, Practice, & Policy AU - Hecht, Alan D AU - Sanders, William H, III AD - Environmental Protection Agency hecht.alan@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 54 EP - 56 PB - USGS Biological Informatics Office, Reston VA VL - 3 IS - 2 SN - 1548-7733, 1548-7733 KW - Sustainable Development KW - Urban Areas KW - Government Agencies KW - Environmental Policy KW - article KW - 2656: environmental interactions; environmental interactions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/61669360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Sustainability%3A+Science%2C+Practice%2C+%26+Policy&rft.atitle=Rejoinder%3A+How+EPA+Research%2C+Policies%2C+and+Programs+Can+Advance+Urban+Sustainability&rft.au=Hecht%2C+Alan+D%3BSanders%2C+William+H%2C+III&rft.aulast=Hecht&rft.aufirst=Alan&rft.date=2007-10-01&rft.volume=3&rft.issue=2&rft.spage=54&rft.isbn=&rft.btitle=&rft.title=Sustainability%3A+Science%2C+Practice%2C+%26+Policy&rft.issn=15487733&rft_id=info:doi/ L2 - http://ejournal.nbii.org/index.html LA - English DB - Sociological Abstracts N1 - Date revised - 2008-08-07 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Government Agencies; Sustainable Development; Urban Areas; Environmental Policy ER - TY - JOUR T1 - Aquifer-based ground-water management AN - 50644854; 2008-107583 AB - Ground-water management often proceeds without all parties recognizing that they are managing the same aquifer. This has resulted in a fragmented, often ineffective, and sometimes contradictory, non-resource-based approach to ground-water management. Effective ground-water protection and management relies on recognition by state and local governments that there is a common unit of management and therefore common interests in proper management of the resource. It is not logical to attempt to manage a part of an aquifer without sufficient understandings about the entire aquifer. The different local, State and Federal programs that have authority and responsibility for ground-water management should have a common understanding of the nature of the occurrence ground water within their respective areas of jurisdiction. Aquifers and aquifer systems are the natural units of management for ground water just as a stream; lake and watershed are natural units of management for surface water. An aquifer is defined (USGS) as: a geologic formation, group of formations or part of a formation that will yield usable quantities of water to a well or spring. It is obvious from this definition that most geologic formations will function as an aquifer, at least over part of its occurrence. Aquifers have mappable boundaries that are delineated based on geologic features (formation boundaries), hydrologic features (flow system divides) and water quality. Aquifers have hydrologic characteristics/properties that are routinely assessed by standardized methods. Under non-perturbed conditions the total annual recharge to an aquifer is balanced by the total annual discharge from the aquifer. Within an aquifer there are aquifer zones, which can be defined as sub-divisions of aquifers with differing hydrologic conditions. Aquifer zones include recharge and discharge areas and confined vs. unconfined areas. Aquifer zones are ecologically important in identifying ground-water interactions with surface water systems, including wetlands. The USGS and State Geological Surveys have mapped and assessed hundreds of aquifers and aquifer systems in the US. JF - Abstracts with Programs - Geological Society of America AU - Wireman, Mike AU - Anonymous Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 42 EP - 43 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 6 SN - 0016-7592, 0016-7592 KW - United States KW - protection KW - confined aquifers KW - surface water KW - water management KW - mapping KW - properties KW - ground water KW - evaluation KW - aquifers KW - recharge KW - wetlands KW - identification KW - discharge KW - water resources KW - unconfined aquifers KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50644854?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Aquifer-based+ground-water+management&rft.au=Wireman%2C+Mike%3BAnonymous&rft.aulast=Wireman&rft.aufirst=Mike&rft.date=2007-10-01&rft.volume=39&rft.issue=6&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2007 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2008-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - aquifers; confined aquifers; discharge; evaluation; ground water; identification; mapping; properties; protection; recharge; surface water; unconfined aquifers; United States; water management; water resources; wetlands ER - TY - JOUR T1 - Effects of historical sediment loading at Halfway Creek marsh, Upper Mississippi River National Wildlife and Fish Refuge, Wisconsin AN - 50643257; 2008-107532 AB - The sedimentation history of Halfway Creek marsh near La Crosse, Wis. was examined during 2005-06 as part of a broader U.S. Geological Survey, U.S. EPA, U.S. Fish and Wildlife Service, and University of Wisconsin-Madison study of sediment and nutrient loadings to the Upper Mississippi River bottomlands. Historical (1860-2006) sedimentation patterns and rates were interpreted from topographic surveys and sediment cores collected from the marsh and upstream floodplains. Historical maps and aerial photographs were used to establish the timing of disturbances and to document channel changes after Euro-American settlement. Episodic sedimentation patterns and rates were linked to watershed agricultural activity, large floods, artificial levee construction, channel alterations, and dam failures. These activities and events affected sedimentation on and between levees, the development of alluvial fans and floodplain splays, and the general pattern of floodplain sedimentation through the marsh. Episodically deposited historical overbank deposits, mainly composed of silty fine sand, are 1.2-1.8 m thick in the marsh, representing a total volume of approximately 1.38 million cubic meters. Sedimentation rates were highest from 1919-1936 when an average rate of 20,560 m3yr-1 exceeded by about 30 times the 1846-1885 rate of 705 m3yr-1 and exceeded by seven times the 1994-2006 rate of 2,860 m3yr-1. The 1994-2006 sedimentation rate represents the lowest since Euro-American settlement, but sedimentation continues especially on natural levees along the channel of Halfway Creek through the lower marsh. Historical overbank deposits affect modern fluvial processes and wetland/fluvial and vegetation dynamics. System-wide adjustments to historical sediment loading will continue for decades and centuries, mainly during moderate and extreme floods that remobilize stored sediment from upstream channel margins and transport it downstream into the marsh and eventually to the Mississippi River. The impact of human activities, frequency and magnitude of overbank sediment loading events, and continued fluvial adjustments, observed at Halfway Creek Marsh are representative of numerous tributaries that flow into critical back-water marshes along the Upper Mississippi River National Wildlife and Fish Refuge. JF - Abstracts with Programs - Geological Society of America AU - Fitzpatrick, Faith A AU - Knox, James C AU - Schubauer-Berigan, Joseph P AU - Anonymous Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 34 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 6 SN - 0016-7592, 0016-7592 KW - United States KW - Upper Mississippi Valley KW - La Crosse Wisconsin KW - stream transport KW - geologic hazards KW - Mississippi Valley KW - floodplains KW - Halfway Creek Marsh KW - Halfway Creek KW - topography KW - sedimentation rates KW - sediments KW - floods KW - Wisconsin KW - La Crosse County Wisconsin KW - Upper Mississippi River National Wildlife and Fish Refuge KW - sand KW - patterns KW - sediment transport KW - marshes KW - clastic sediments KW - sedimentation KW - agriculture KW - nutrients KW - levees KW - history KW - mires KW - fluvial features KW - 06A:Sedimentary petrology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50643257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Effects+of+historical+sediment+loading+at+Halfway+Creek+marsh%2C+Upper+Mississippi+River+National+Wildlife+and+Fish+Refuge%2C+Wisconsin&rft.au=Fitzpatrick%2C+Faith+A%3BKnox%2C+James+C%3BSchubauer-Berigan%2C+Joseph+P%3BAnonymous&rft.aulast=Fitzpatrick&rft.aufirst=Faith&rft.date=2007-10-01&rft.volume=39&rft.issue=6&rft.spage=34&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2007 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2008-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - agriculture; clastic sediments; floodplains; floods; fluvial features; geologic hazards; Halfway Creek; Halfway Creek Marsh; history; La Crosse County Wisconsin; La Crosse Wisconsin; levees; marshes; mires; Mississippi Valley; nutrients; patterns; sand; sediment transport; sedimentation; sedimentation rates; sediments; stream transport; topography; United States; Upper Mississippi River National Wildlife and Fish Refuge; Upper Mississippi Valley; Wisconsin ER - TY - JOUR T1 - A systematic data-driven approach to evaluating hydraulic capture at Superfund sites in USEPA Region 5 AN - 50642597; 2008-105948 AB - We are developing systematic methods for evaluating monitoring data as part of the CERCLA five-year review process. These methods take advantage of standardized data formats in USEPA's Region 5 guidance for electronic data deliverables (EDDs) adopted in part by 6 of the 10 U.S. EPA regional offices, many state environmental agencies, and other users of environmental data. This presentation focuses on the use of mapping-based techniques to illustrate the likely extent of hydraulic capture by pump and treat systems. The extent of groundwater contaminated above cleanup levels for any contaminant of concern (COC) is mapped as a Composite Target Zone (CTZ). The CTZ is based upon the upper 95% confidence limit (UCL) of recent measurements for each COC at each monitoring point as calculated using PAM intrawell statistical analysis software developed by Subterranean Research. These methods require data for water levels, contaminant concentrations, and pumping rates that can be rapidly manipulated, evaluated for quality control, and summarized into discrete data sets. The mapping uses universal kriging, embedding equations that describe the response of the potentiometric surface to extraction or injection wells and discharge to/from surface water bodies. Particle tracking is used with the mapped surface(s) to approximate capture zones. If a groundwater flow model is available, related mapping techniques can be used to incorporate simulation results as a trend or "drift". Automation of database queries, kriging, and particle-tracking routines enables relatively rapid evaluation of hydraulic capture at multiple time periods, and stochastic (frequentist) approaches. Dozens of discrete time period maps may be evaluated simultaneously to develop capture probability maps. The efficiency and cost-effectiveness of these analyses is dependent upon data standardization and quality review. While automation of mapping can be effective, it does not mitigate the need for thoughtful assessment of the site. For example, analyses can reveal significant concerns unrelated to hydraulic capture, such as conflicts between proposed treatment technologies and the groundwater redox conditions, or capture-related concerns such as inadequate pumping rate data or infelicitous monitoring well locations. JF - Abstracts with Programs - Geological Society of America AU - Cohen, Harvey A AU - Tonkin, Matthew J AU - Wilson, David AU - Dougherty, David E AU - Anonymous Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 18 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 6 SN - 0016-7592, 0016-7592 KW - United States KW - methods KW - digital data KW - monitoring KW - Superfund KW - statistical analysis KW - kriging KW - government agencies KW - U. S. Environmental Protection Agency KW - pollution KW - potentiometric surface KW - mapping KW - ground water KW - evaluation KW - water treatment KW - quality control KW - pump-and-treat KW - water wells KW - water pollution KW - Superfund sites KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50642597?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=A+systematic+data-driven+approach+to+evaluating+hydraulic+capture+at+Superfund+sites+in+USEPA+Region+5&rft.au=Cohen%2C+Harvey+A%3BTonkin%2C+Matthew+J%3BWilson%2C+David%3BDougherty%2C+David+E%3BAnonymous&rft.aulast=Cohen&rft.aufirst=Harvey&rft.date=2007-10-01&rft.volume=39&rft.issue=6&rft.spage=18&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2007 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2008-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - digital data; evaluation; government agencies; ground water; kriging; mapping; methods; monitoring; pollution; potentiometric surface; pump-and-treat; quality control; statistical analysis; Superfund; Superfund sites; U. S. Environmental Protection Agency; United States; water pollution; water treatment; water wells ER - TY - JOUR T1 - What does geology have to do with it? Informed decision making regarding environmental impacts of mining AN - 50560810; 2008-131866 AB - Based upon experiences at the U.S. EPA, this paper will explore systematic evaluation of mineral deposit types to help decision-making by both mining companies (increasing profits) and by regulators (diminishing environmental and human health impacts). Examples of both successes and failures in the understanding of the mechanisms of environmental impacts will illustrate the importance of classification systems such as geoenvironmental models. Practical application of this data could make decision-making more efficient and effective, providing insight into environmental impacts of mineral deposits JF - Abstracts with Programs - Geological Society of America AU - Russell, Carol Cox AU - Anonymous Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 102 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 6 SN - 0016-7592, 0016-7592 KW - United States KW - mining geology KW - classification KW - government agencies KW - U. S. Environmental Protection Agency KW - mechanism KW - decision-making KW - applications KW - mineral resources KW - environmental effects KW - evaluation KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50560810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=What+does+geology+have+to+do+with+it%3F+Informed+decision+making+regarding+environmental+impacts+of+mining&rft.au=Russell%2C+Carol+Cox%3BAnonymous&rft.aulast=Russell&rft.aufirst=Carol&rft.date=2007-10-01&rft.volume=39&rft.issue=6&rft.spage=102&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2007 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2008-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - applications; classification; decision-making; environmental effects; evaluation; government agencies; mechanism; mineral resources; mining geology; U. S. Environmental Protection Agency; United States ER - TY - JOUR T1 - Refinements in source profiles from coal-fired utility boilers based on trace element solubility perspectives AN - 50524023; 2009-014033 AB - In the spring of 2006, the U.S. EPA conducted a study to update source profiles from coal-fired utility boilers. The host facility was a 125 MW, low sulfur (<0.7%), Eastern bituminous coal-fired utility boiler equipped with a cold-side electrostatic precipitator (ESP). Co-located sets of fine fraction (<2.5 micron mass median aerodynamic diameter) particulate matter samples were acquired on three separate days using a dilution sampler system (DSS) from stack sampling ports located at a ground elevation of approximately 40 meters. The DSS dilutes stack emissions (1:35) with clean ambient air, and provides sufficient residence time at near-ambient temperature and pressure to allow condensation and coagulation of particulate matter. While particulate samples were being collected, total gas phase mercury emissions were quantified using a Tekran series 3300 continuous emission monitoring system. The PM2.5 total metal concentrations were determined using energy dispersive X-ray fluorescence (ED-XRF). The water and dilute acid extractable metal concentrations were subsequently quantified using high resolution inductively coupled plasma mass spectrometry (HR-ICPMS). In combination, these total concentration as well as solubility based trace element and mercury emission profiles will produce new insights from source apportionment and environmental impact perspectives. JF - Abstracts with Programs - Geological Society of America AU - Graney, Joseph R AU - Landis, Matthew S AU - Anonymous Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 174 PB - Geological Society of America (GSA), Boulder, CO VL - 39 IS - 6 SN - 0016-7592, 0016-7592 KW - government agencies KW - mass spectra KW - environmental effects KW - bituminous coal KW - air pollution KW - sedimentary rocks KW - quantitative analysis KW - coal KW - X-ray fluorescence spectra KW - spectra KW - particulate materials KW - trace elements KW - mercury KW - high-resolution methods KW - monitoring KW - elevation KW - U. S. Environmental Protection Agency KW - pollution KW - solubility KW - samplers KW - samples KW - ICP mass spectra KW - metals KW - instruments KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50524023?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Refinements+in+source+profiles+from+coal-fired+utility+boilers+based+on+trace+element+solubility+perspectives&rft.au=Graney%2C+Joseph+R%3BLandis%2C+Matthew+S%3BAnonymous&rft.aulast=Graney&rft.aufirst=Joseph&rft.date=2007-10-01&rft.volume=39&rft.issue=6&rft.spage=174&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2007 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2009-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - air pollution; bituminous coal; coal; elevation; environmental effects; government agencies; high-resolution methods; ICP mass spectra; instruments; mass spectra; mercury; metals; monitoring; particulate materials; pollution; quantitative analysis; samplers; samples; sedimentary rocks; solubility; spectra; trace elements; U. S. Environmental Protection Agency; X-ray fluorescence spectra ER - TY - JOUR T1 - Science, risk, and risk assessment and their role(s) supporting environmental risk management AN - 36972943; 3774819 AB - The U.S. Environmental Protection Agency (EPA) fulfills its mission of protecting public health and the environment by, among other things, developing and enforcing regulations that implement environmental laws enacted by Congress. Ensuring that its regulations have a sound analytical foundation reduces both controversy and, to some extent, court challenges, and increases the likelihood of compliance by the regulated community, which is key to achieving real environmental improvement. The environment, risk, and environmental risk are case- or site-specific and too complex to capture fully. EPA uses risk assessment as a key source of scientific information along with other relevant information (e.g., costs) for making good, sound decisions about managing risks to human health and the environment. Risk assessment is a necessary tool used to inform decisions where direct measurements are not possible. While risk assessment involves science and is a scientific activity, it is best described as 'trans-scientific'; normative elements and judgment are inherent. EPA has instituted numerous processes and systems to make risk assessments tractable and feasible, while ensuring their overall quality. This Article reviews risk assessment and its role in risk management decisions, with emphasis on science and policy influences on procedures for conducting such assessments and making such decisions, and vice versa. JF - Environmental law AU - Hetes, Robert G AD - U.S. Environmental Protection Agency Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 1007 EP - 1026 VL - 37 IS - 4 SN - 0046-2276, 0046-2276 KW - Political Science KW - Risk management KW - Law KW - Policy making KW - Empirical research KW - Environmental law KW - Science KW - Environmental policy KW - Environmental protection UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36972943?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+law&rft.atitle=Science%2C+risk%2C+and+risk+assessment+and+their+role%28s%29+supporting+environmental+risk+management&rft.au=Hetes%2C+Robert+G&rft.aulast=Hetes&rft.aufirst=Robert&rft.date=2007-10-01&rft.volume=37&rft.issue=4&rft.spage=1007&rft.isbn=&rft.btitle=&rft.title=Environmental+law&rft.issn=00462276&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 11038 7625; 4329 7253; 9625 9628; 4336 5574 10472; 4200 10902; 11325; 7253; 4339 ER - TY - JOUR T1 - Law, science, and the environment forum: a meeting of the minds AN - 36972910; 3774966 JF - Environmental law AU - Adelman, David E AU - Angelo, Mary Jane AU - Brown, Mark T AU - Brosnan, Deborah M AU - Hetes, Robert G AU - McGarity, Thomas O AU - Ruhl, J B AU - Shapiro, Sidney A AU - Boudreaux, Paul AU - Owen, Dave AU - Brodeen, Elizabeth C AD - University of Arizona ; University of Florida ; Sustainable Ecosystems Institute ; U.S. Environmental Protection Agency ; University of Texas ; Florida State University ; Wake Forest University ; Stetson University ; University of Maine ; Lewis and Clark Law School Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 931 EP - 1239 VL - 37 IS - 4 SN - 0046-2276, 0046-2276 KW - Political Science KW - Agriculture KW - Courts KW - Environmental economics KW - Environmental science KW - Forests KW - Biodiversity KW - Policy making KW - Regulation KW - California KW - Case studies KW - Scientists KW - Environmental law KW - Species KW - Common law KW - Reliability KW - Empirical research KW - Toxicity KW - U.S.A. KW - Environmental policy KW - Science KW - Environmental protection KW - Sustainability KW - Decision making KW - Risk management KW - Government KW - Conservation KW - Agency UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/36972910?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+law&rft.atitle=Law%2C+science%2C+and+the+environment+forum%3A+a+meeting+of+the+minds&rft.au=Adelman%2C+David+E%3BAngelo%2C+Mary+Jane%3BBrown%2C+Mark+T%3BBrosnan%2C+Deborah+M%3BHetes%2C+Robert+G%3BMcGarity%2C+Thomas+O%3BRuhl%2C+J+B%3BShapiro%2C+Sidney+A%3BBoudreaux%2C+Paul%3BOwen%2C+Dave%3BBrodeen%2C+Elizabeth+C&rft.aulast=Adelman&rft.aufirst=David&rft.date=2007-10-01&rft.volume=37&rft.issue=4&rft.spage=931&rft.isbn=&rft.btitle=&rft.title=Environmental+law&rft.issn=00462276&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - SuppNotes - Collection of 10 articles N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 11325; 4329 7253; 11350 10935 13682; 9625 9628; 12807 9818; 12113 4831 1601 8560 9511 4309; 4316 4025; 12434; 11038 7625; 4200 10902; 4339; 2562 7253; 2971 7014 7019 7016 9965; 10742; 2056 10902; 4342 11325; 5551; 656; 1601 8560 9511 4309; 3322 6071 1542 11325; 10761; 2729; 5243 7197 8560 9511 4309; 827; 4336 5574 10472; 433 293 14; 72 433 293 14 ER - TY - JOUR T1 - Mercury Concentration in Frozen Whole-Fish Homogenates Is Insensitive to Holding Time AN - 21001144; 7623470 AB - Current recommended holding times for the analysis of total mercury (Hg) in fish tissue ranges from 28 to 180 days. In 2006, we evaluated the effect of an extended holding time on Hg concentrations by reanalyzing whole-fish wet homogenates that were analyzed originally in 2002 and had been stored frozen at -20 degree C since that time. Seven species, 13-15 samples each, were reanalyzed. Comparisons of concentration differences between 2006 and 2002 indicated that no statistically significant changes in Hg concentrations occurred in any of the seven fish species. These results indicate that wet fish tissue homogenates can be held frozen for at least four years without affecting analytical results, thus extending holding times far beyond those currently recommended. JF - Archives of Environmental Contamination and Toxicology AU - Peterson, Spencer A AU - Peck, David V AU - Sickle, John AU - Hughes, Robert M AD - US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, 200 SW 35th Street, Corvallis, OR, 97333, USA, Peterson.spencer@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 411 EP - 417 PB - Springer-Verlag, 175 Fifth Ave. New York NY 10010 USA, [mailto:orders@springer-ny.com] VL - 53 IS - 3 SN - 0090-4341, 0090-4341 KW - Pollution Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Toxicology Abstracts KW - Contamination KW - Statistical analysis KW - Toxicity KW - Pisces KW - Bioaccumulation KW - Water Pollution Effects KW - Mercury KW - Fish KW - Toxicology KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - AQ 00008:Effects of Pollution KW - X 24360:Metals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21001144?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Environmental+Contamination+and+Toxicology&rft.atitle=Mercury+Concentration+in+Frozen+Whole-Fish+Homogenates+Is+Insensitive+to+Holding+Time&rft.au=Peterson%2C+Spencer+A%3BPeck%2C+David+V%3BSickle%2C+John%3BHughes%2C+Robert+M&rft.aulast=Peterson&rft.aufirst=Spencer&rft.date=2007-10-01&rft.volume=53&rft.issue=3&rft.spage=411&rft.isbn=&rft.btitle=&rft.title=Archives+of+Environmental+Contamination+and+Toxicology&rft.issn=00904341&rft_id=info:doi/10.1007%2Fs00244-006-0237-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Mercury; Toxicology; Statistical analysis; Bioaccumulation; Toxicity; Contamination; Water Pollution Effects; Fish; Pisces DO - http://dx.doi.org/10.1007/s00244-006-0237-6 ER - TY - JOUR T1 - Enhancing hydrological simulation program - FORTRAN model channel hydraulic representation AN - 20993292; 7626246 AB - The hydrological simulation program - FORTRAN (HSPF) is a comprehensive watershed model that employs depth-area-volume-flow relationships known as the hydraulic function table (FTABLE) to represent the hydraulic characteristics of stream channel cross-sections and reservoirs. An accurate FTABLE determination for a stream cross-section site requires an accurate determination of mean flow depth, mean flow width, roughness coefficient, longitudinal bed slope, and length of stream reach. A method that uses regional regression equations to estimate mean flow depth, mean flow width, and roughness coefficient is presented herein. FTABLES generated by the proposed method (Alternative Method) and FTABLES generated by Better Assessment Science Integrating Point and Nonpoint Sources (BASINS) were compared. As a result, the Alternative Method was judged to be an enhancement over the BASINS method. First, the Alternative Method employs a spatially variable roughness coefficient, whereas BASINS employs an arbitrarily selected spatially uniform roughness coefficient. Second, the Alternative Method uses mean flow width and mean flow depth estimated from regional regression equations whereas BASINS uses mean flow width and depth extracted from the National Hydrography Dataset (NHD). Third, the Alternative Method offers an option to use separate roughness coefficients for the in-channel and floodplain sections of compound channels. Fourth, the Alternative Method has higher resolution in the sense that area, volume, and flow data are calculated at smaller depth intervals than the BASINS method. To test whether the Alternative Method enhances channel hydraulic representation over the BASINS method, comparisons of observed and simulated streamflow, flow velocity, and suspended sediment were made for four test watersheds. These comparisons revealed that the method used to estimate the FTABLE has little influence on hydrologic calibration, but greatly influences hydraulic and suspended sediment calibration. The hydrologic calibration results showed that observed versus simulated daily streamflow comparisons had Nash-Sutcliffe efficiencies ranging from 0.50 to 0.61 and monthly comparisons had efficiencies ranging from 0.61 to 0.84. Comparisons of observed and simulated suspended sediments concentrations had model efficiencies ranging from 0.48 to 0.56 for the daily, and 0.28 to 0.70 for the monthly comparisons. The overall results of the hydrological, hydraulic, and suspended sediment concentration comparisons show that the Alternative Method yielded a relatively more accurate FTABLE than the BASINS method. This study concludes that hydraulic calibration enhances suspended sediment simulation performance, but even greater improvement in suspended sediment calibration can be achieved when hydrological simulation performance is improved. Any improvements in hydrological simulation performance are subject to improvements in the temporal and spatial representation of the precipitation data. JF - Journal of the American Water Resources Association AU - Mohamoud, Y M AD - USEPA National Exposure Research Laboratory, 960 College Road, Athens, Georgia 30605, USA, mohamoud.yusuf@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 1280 EP - 1292 VL - 43 IS - 5 SN - 1093-474X, 1093-474X KW - Meteorological & Geoastrophysical Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Aqualine Abstracts; Water Resources Abstracts KW - Hydraulics KW - Precipitation data KW - Water reservoirs KW - Statistical analysis KW - Water resources KW - Watersheds KW - Streams KW - Resuspended sediments KW - Hydrologic Models KW - Calibrations KW - Hydrography KW - Reservoirs KW - Suspended Sediments KW - Hydrologic analysis KW - Mathematical models KW - Streamflow KW - Stream flow KW - Channels KW - Roughness Coefficient KW - Performance Evaluation KW - Flood plains KW - Numerical simulations KW - AQ 00001:Water Resources and Supplies KW - Q2 09142:Methods and instruments KW - SW 6010:Structures KW - M2 556.1:Hydrologic Cycle (556.1) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20993292?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Enhancing+hydrological+simulation+program+-+FORTRAN+model+channel+hydraulic+representation&rft.au=Mohamoud%2C+Y+M&rft.aulast=Mohamoud&rft.aufirst=Y&rft.date=2007-10-01&rft.volume=43&rft.issue=5&rft.spage=1280&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2007.00113.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Channels; Resuspended sediments; Water reservoirs; Flood plains; Mathematical models; Hydrography; Water resources; Watersheds; Stream flow; Precipitation data; Hydrologic analysis; Numerical simulations; Statistical analysis; Reservoirs; Roughness Coefficient; Hydraulics; Performance Evaluation; Suspended Sediments; Hydrologic Models; Calibrations; Streamflow; Streams DO - http://dx.doi.org/10.1111/j.1752-1688.2007.00113.x ER - TY - JOUR T1 - Utilizing the Chemical Mass Balance and Positive Matrix Factorization models to determine influential species and examine possible rotations in receptor modeling results AN - 20673952; 8181714 AB - Data from two of the United States Environmental Protection Agency's Speciation Trends Network fine particulate matter sites within Chicago, Illinois were used to examine the influence that the results and profiles of the Chemical Mass Balance (CMB) receptor model have on the source contributions and profiles of the Positive Matrix Factorization (PMF) model. This was accomplished using the target shape technique, which utilizes a priori information from the CMB source profiles inputted into the PMF model. The target shape methodology involves inputting specific information for the source profiles into the PMF model as it is resolving source profile and contribution matrices. The target shape results demonstrated it is possible to determine in both the CMB and PMF source profiles those species, which do not influence the solutions of either model. A second method utilizing information from the CMB results was used to impose a condition where the Motor Vehicles source never had a zero contribution as was applied to the CMB model. This involved utilizing an edge rotation to rotate the PMF results to yield a different solution without worsening the fit of the original results. The purpose of this work is to achieve a rotation, which produced a PMF solution where all of the Motor Vehicles contributions were greater than zero. Comparing the rotated Motor Vehicles and Sulfates source contributions in PMF to those obtained from CMB showed a better correlation between the PMF Motor Vehicles contributions to the original CMB results than those prior to rotation. JF - Atmospheric Environment AU - Rizzo, MJ AU - Scheff, P A AD - Office of Air Quality Planning and Standards, Air Quality Analysis Division, Air Quality Analysis Group, Research Triangle Park, NC 27711, USA, rizzo.michael@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 6986 EP - 6998 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 33 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - USA, Illinois, Chicago KW - Sulfates KW - Atmospheric pollution models KW - USA, Illinois KW - Motor vehicles KW - Correlations KW - Particulates KW - Atmospheric pollution by motor vehicles KW - Environmental protection KW - EPA KW - Sulfate sources KW - Atmospheric chemistry models KW - P 9000:ENVIRONMENTAL ACTION KW - M2 551.510.42:Air Pollution (551.510.42) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20673952?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Utilizing+the+Chemical+Mass+Balance+and+Positive+Matrix+Factorization+models+to+determine+influential+species+and+examine+possible+rotations+in+receptor+modeling+results&rft.au=Rizzo%2C+MJ%3BScheff%2C+P+A&rft.aulast=Rizzo&rft.aufirst=MJ&rft.date=2007-10-01&rft.volume=41&rft.issue=33&rft.spage=6986&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.05.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Sulfate sources; Atmospheric pollution models; Atmospheric chemistry models; Correlations; Atmospheric pollution by motor vehicles; Environmental protection; Sulfates; EPA; Motor vehicles; Particulates; USA, Illinois, Chicago; USA, Illinois DO - http://dx.doi.org/10.1016/j.atmosenv.2007.05.008 ER - TY - JOUR T1 - The effects of meteorology on ozone in urban areas and their use in assessing ozone trends AN - 20668764; 8181704 AB - The United States Environmental Protection Agency issues periodic reports that describe air quality trends in the US. For some pollutants, such as ozone, both observed and meteorologically adjusted trends are displayed. This paper describes an improved statistical methodology for meteorologically adjusting ozone trends as well as characterizes the relationships between individual meteorological parameters and ozone. A generalized linear model that accommodates the nonlinear effects of the meteorological variables was fit to data collected for 39 major eastern US urban areas. Overall, the model performs very well, yielding R super(2) statistics as high as 0.80. The analysis confirms that ozone is generally increasing with increasing temperature and decreasing with increasing relative humidity. Examination of the spatial gradients of these responses show that the effect of temperature on ozone is most pronounced in the north while the opposite is true of relative humidity. By including HYSPLIT-derived transport wind direction and distance in the model, it is shown that the largest incremental impact of wind direction on ozone occurs along the periphery of the study domain, which encompasses major NO sub(x) emission sources. JF - Atmospheric Environment AU - Camalier, L AU - Cox, W AU - Dolwick, P AD - Planning, and Standards, US Environmental Protection Agency, RTP, NC 27711, USA, Camalier.Louise@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 7127 EP - 7137 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 33 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Relative humidity KW - Meteorological data KW - Ozone measurements KW - Atmospheric pollution models KW - Statistical analysis KW - Air quality KW - Ozone in troposphere KW - Meteorological parameters KW - Emissions KW - Meteorology KW - Ozone KW - Urban areas KW - Atmospheric pollution KW - Temperature KW - Humidity KW - Ozone trends KW - Wind direction KW - Environmental protection KW - EPA KW - USA KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20668764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=The+effects+of+meteorology+on+ozone+in+urban+areas+and+their+use+in+assessing+ozone+trends&rft.au=Camalier%2C+L%3BCox%2C+W%3BDolwick%2C+P&rft.aulast=Camalier&rft.aufirst=L&rft.date=2007-10-01&rft.volume=41&rft.issue=33&rft.spage=7127&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.04.061 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Relative humidity; Meteorological data; Ozone measurements; Atmospheric pollution; Atmospheric pollution models; Statistical analysis; Ozone trends; Air quality; Wind direction; Environmental protection; Ozone in troposphere; Meteorological parameters; Meteorology; EPA; Emissions; Temperature; Humidity; Urban areas; Ozone; USA DO - http://dx.doi.org/10.1016/j.atmosenv.2007.04.061 ER - TY - JOUR T1 - Enhanced mutagenesis of Salmonella tester strains due to deletion of genes other than uvrB AN - 20641217; 7763422 AB - The standard Salmonella mutagenicity (Ames) tester strains are missing 15-119 genes due to the extended (gal-bio-uvrB) mutations that render the strains excision-repair deficient (uvrB). We constructed strains of Salmonella that are homologous to tester strains TA98 and TA100 except that in place of the uvrB deletion, they contain single-gene defects in either uvrB, moaA, moeA, or both uvrB and moeA. We then tested the following mutagens in these strains: 2-acetylaminofluorene, Glu-P-1, 4-aminobiphenyl, benzo[a]pyrene, MX, 1-nitropyrene, 6-hydroxylaminopurine (HAP), and 2-amino-6-hydroxylaminopurine (AHAP). We confirmed in Salmonella a previous finding in Escherichia coli that the enhanced mutagenicity of the purine analogues HAP and AHAP is not due to the deletion of the uvrB gene but due to the deletion of moeA and/or moaA, which are involved in molybdenum cofactor biosynthesis. The spontaneous mutant frequency and induced mutagenic potency of mutagens due to the extended uvrB mutation are due largely to the deletion of uvrB and to some extent of moeA/moaA at the frameshift hisD3052 allele of TA98 but involve other genes in addition to uvrB and moeA/moaA at the base-substitution hisG46 allele of TA100. The extended uvrB mutation does not prevent the detection of mutagens that would have been detected in a strain containing a single uvrB defect. Because of the deletion of moeA/moaA, the extended uvrB deletion generally enhanced spontaneous and induced mutagenicity, especially at the base-substitution allele. This enhanced sensitivity may underlay the severe health effects in humans who have mutations in molybdenum cofactor biosynthesis genes. JF - Environmental and Molecular Mutagenesis AU - Swartz, Carol D AU - Parks, Nick AU - Umbach, David M AU - Ward, William O AU - Schaaper, Roel M AU - Demarini, David M AD - Department of Environmental Science and Engineering, University of North Carolina, Chapel Hill, North Carolina, demarini.david@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 694 EP - 705 PB - John Wiley & Sons, 111 River Street Hoboken NJ 07030 USA, [mailto:custserv@wiley.com], [URL:http://www.wiley.com/] VL - 48 IS - 8 SN - 0893-6692, 0893-6692 KW - Microbiology Abstracts B: Bacteriology; Genetics Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - uvrB gene KW - Mutagens KW - Mutagenicity KW - Molybdenum KW - 1-Nitropyrene KW - Mutant frequency KW - purines KW - Mutagenesis KW - Gene deletion KW - Cofactors KW - Escherichia coli KW - Benzo(a)pyrene KW - Salmonella KW - Mutation KW - N 14840:Antisense, Nucleotide Analogs KW - J 02400:Human Diseases KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20641217?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+and+Molecular+Mutagenesis&rft.atitle=Enhanced+mutagenesis+of+Salmonella+tester+strains+due+to+deletion+of+genes+other+than+uvrB&rft.au=Swartz%2C+Carol+D%3BParks%2C+Nick%3BUmbach%2C+David+M%3BWard%2C+William+O%3BSchaaper%2C+Roel+M%3BDemarini%2C+David+M&rft.aulast=Swartz&rft.aufirst=Carol&rft.date=2007-10-01&rft.volume=48&rft.issue=8&rft.spage=694&rft.isbn=&rft.btitle=&rft.title=Environmental+and+Molecular+Mutagenesis&rft.issn=08936692&rft_id=info:doi/10.1002%2Fem.20343 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - uvrB gene; Mutagens; Mutagenicity; Gene deletion; Cofactors; Molybdenum; 1-Nitropyrene; Benzo(a)pyrene; Mutant frequency; Mutation; purines; Mutagenesis; Escherichia coli; Salmonella DO - http://dx.doi.org/10.1002/em.20343 ER - TY - JOUR T1 - Framework for Metals Risk Assessment AN - 20638788; 7630915 AB - EPA recognized that metals present unique risk assessment issues, and saw the need to develop a framework document that puts forth key scientific principles for metals risk assessments to help ensure consistency in metals assessments across EPA programs and regional offices. This framework, called the ''Framework for Metals Risk Assessment,'' is a science-based document that describes basic principles that address the special attributes and behaviors of metals and metal compounds to be considered when assessing their human health and ecological risks. The Risk Assessment Forum oversaw the development of this document, including input from stakeholders and experts throughout the Agency, and obtained through several expert workshops, followed by peer review by the EPA Science Advisory Board (SAB). The Framework for Metals Risk Assessment document is intended to serve as a guide for all EPA programs and regional offices to supplement or update the policies, practices and guidance they currently use in their respective metals assessments. This framework document is not a prescriptive guide on how any particular type of assessment should be conducted within an EPA program office. Rather, it outlines key metal principles and describes how they should be considered in conducting human health and ecological risk assessments to advance our understanding of metals impact and foster consistency across EPA programs and regions. Although the audience for the framework is primarily intended to be Agency risk assessors, it also will communicate principles and recommendations for metals risk assessment to stakeholders and the public. This framework will be used in conjunction with guidance developed by the programs and regions for site-specific risk assessment, criteria derivation, ranking or categorization and other similar Agency activities related to metals. The Framework for Metals Risk Assessment document is intended to serve as a guide for all EPA programs and regional offices to supplement or update the policies, practices and guidance they currently use in their respective metals assessments. EPA assessments can vary in level of detail from simple, screening analyses to complex, definitive assessments. More complex scientific tools and metal specific methods should be applied as the complexity of the hazard assessment or risk assessment increases. JF - Ecotoxicology and Environmental Safety AU - Fairbrother, A AU - Wenstel, R AU - Sappington, K AU - Wood, W AD - Risk Assessment Forum, US Environmental Protection Agency, Washington, DC 20460, USA, wentsel.randy@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 145 EP - 227 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 68 IS - 2 SN - 0147-6513, 0147-6513 KW - Pollution Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts KW - Risk assessment KW - EPA KW - Metals KW - Reviews KW - Environmental impact KW - stakeholders KW - Public health KW - H 3000:Environment and Ecology KW - X 24360:Metals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20638788?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecotoxicology+and+Environmental+Safety&rft.atitle=Framework+for+Metals+Risk+Assessment&rft.au=Fairbrother%2C+A%3BWenstel%2C+R%3BSappington%2C+K%3BWood%2C+W&rft.aulast=Fairbrother&rft.aufirst=A&rft.date=2007-10-01&rft.volume=68&rft.issue=2&rft.spage=145&rft.isbn=&rft.btitle=&rft.title=Ecotoxicology+and+Environmental+Safety&rft.issn=01476513&rft_id=info:doi/10.1016%2Fj.ecoenv.2007.03.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-11-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Metals; Reviews; EPA; Environmental impact; stakeholders; Public health DO - http://dx.doi.org/10.1016/j.ecoenv.2007.03.015 ER - TY - JOUR T1 - Incorporating Results of Avian Toxicity Tests into a Model of Annual Reproductive Success AN - 20576742; 7724583 AB - Modeling the effects of pesticide exposure on avian populations requires knowledge of how the pesticide changes survival and fecundity rates for the population. Although avian reproduction tests are the primary source of information on reproductive effects in the pesticide risk assessment process, current tests cannot provide a direct estimate of the effects of a pesticide on fecundity rates. We present a mathematical model that integrates information on specific types of effects from reproduction tests with information on avian life history parameters, the timing of pesticide applications, and the temporal pattern of pesticide exposure levels to estimate pesticide effects on annual reproductive success. The model demonstration follows nesting success of females in no-pesticide or pesticide-exposed populations through a breeding season to estimate the mean number of successful broods per female. We demonstrate the model by simulating populations of a songbird exposed to 1 of 2 hypothetical pesticides during a breeding season. Finally, we discuss several issues for improving the quantitative estimation of annual reproductive success. JF - Integrated Environmental Assessment and Management AU - Bennett, R AU - Etterson, M AD - US Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Laboratory, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804 Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 498 EP - 507 PB - Society of Environmental Toxicology and Chemistry (SETAC), 1010 North 12th Avenue Pensacola FL 32501-3367 USA, [mailto:setac@setac.org], [URL:http://www.setac.org] VL - 3 IS - 4 SN - 1551-3777, 1551-3777 KW - Ecology Abstracts; Toxicology Abstracts KW - Avian reproduction test KW - Annual reproductive success KW - Pesticide KW - Population-level assessment KW - Markov chain models KW - Risk assessment KW - Mathematical models KW - Fecundity KW - Life history KW - Pesticides KW - Survival KW - Reproduction KW - Toxicity KW - Breeding success KW - Pesticide applications KW - X 24300:Methods KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20576742?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Integrated+Environmental+Assessment+and+Management&rft.atitle=Incorporating+Results+of+Avian+Toxicity+Tests+into+a+Model+of+Annual+Reproductive+Success&rft.au=Bennett%2C+R%3BEtterson%2C+M&rft.aulast=Bennett&rft.aufirst=R&rft.date=2007-10-01&rft.volume=3&rft.issue=4&rft.spage=498&rft.isbn=&rft.btitle=&rft.title=Integrated+Environmental+Assessment+and+Management&rft.issn=15513777&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Life history; Fecundity; Mathematical models; Pesticides; Survival; Reproduction; Toxicity; Pesticide applications; Breeding success ER - TY - JOUR T1 - Do statistical inferences allowing three alternative decisions give better feedback for environmentally precautionary decision-making? AN - 20558845; 7551616 AB - Environmental policies and guidelines often specify standards for environmental indicators. The first part of this paper argues that, where compliance with these standards is assessed with the help of statistical inference, an inference employing a three-alternatives decision rule can provide more sensible feedback to environmental managers for precautionary decision-making. The second part of the paper shows how a three-alternatives statistical inference about compliance with a percentile standard might be applied to a small number of observations using a non-parametric binomial interval. This interval expression of uncertainty results in the sample size requirements for various percentile ranks becoming explicit. JF - Journal of Environmental Management AU - Goudey, R AD - Environment Protection Authority, Ernest Jones Drive, Macleod, Vic. 3085, Australia, Rob.Goudey@epa.vic.gov.au Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 338 EP - 344 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 85 IS - 2 SN - 0301-4797, 0301-4797 KW - Pollution Abstracts; Sustainability Science Abstracts; Ecology Abstracts KW - Decision making KW - Statistics KW - guidelines KW - Compliance KW - environmental indicators KW - Feedback KW - Environmental policy KW - P 9000:ENVIRONMENTAL ACTION KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20558845?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Management&rft.atitle=Do+statistical+inferences+allowing+three+alternative+decisions+give+better+feedback+for+environmentally+precautionary+decision-making%3F&rft.au=Goudey%2C+R&rft.aulast=Goudey&rft.aufirst=R&rft.date=2007-10-01&rft.volume=85&rft.issue=2&rft.spage=338&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Management&rft.issn=03014797&rft_id=info:doi/10.1016%2Fj.jenvman.2006.10.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Decision making; Statistics; Feedback; Environmental policy; guidelines; Compliance; environmental indicators DO - http://dx.doi.org/10.1016/j.jenvman.2006.10.012 ER - TY - JOUR T1 - Changes in air quality and atmospheric deposition in the eastern United States: 1990-2004 AN - 20551189; 7634964 AB - Data collected in the eastern United States (U.S.) between 1990 and 2004 at 34 dry and paired wet monitoring sites are examined. A goal is to evaluate the air quality impacts occurring between 1990 and 2004 resulting from legislatively mandated changes in emissions. Three 5-year periods, 1990-1994 (P1), 1995-1999 (P2), and 2000-2004 (P3) are considered. Period- to-period changes in selected pollutant metrics are examined, focusing on P1-to-P3 changes. Data are composed from reported weekly measurements into estimates of means for year, site, and season. The mean squared error derived from analysis of variance applied to these means for atmospheric concentration, dry deposition velocity, precipitation rate, and dry, wet and total deposition is used to examine differences between periods for seasons and predefined regional groupings of sites. Results suggest that relationships exist at the current scale between changes in both concentration and deposition of relevant atmospheric pollutants and changes in SO sub(2) emissions that are generally less than 1:1 and that these disparities are more pronounced for SO sub(4) super(2-) (a reaction product) than SO sub(2) (the primary pollutant). Coincident timing and location suggest that legislatively mandated summertime reductions in estimated NOx emissions contributed strongly to observed reductions of atmospheric HNO sub(3) concentration and dry deposition in the eastern U.S. Less than 1:1 relationships are also indicated at the current scale between changes in both concentration and deposition of the relevant measured secondary atmospheric pollutants, HNO sub(3) and NO sub(3) super(-), and changes in NOx emissions. In the face of P1-to-P3 reductions in estimated emissions of both SO sub(2) and NOx, wintertime changes in the sum of atmospheric SO sub(4) super(2-), NO sub(3) super(-), and NH sub(4) super(+) concentrations, relative to those for corresponding SO sub(4) super(2- ) concentrations, range from reductions that are less than 1:1 to actual increases. JF - Journal of Geophysical Research. Atmospheres AU - Sickles II, Joseph E AU - Shadwick, Douglas S AD - Landscape Characterization Branch, Environmental Sciences Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA Y1 - 2007/10// PY - 2007 DA - Oct 2007 PB - American Geophysical Union, 2000 Florida Ave., N.W. Washington DC 20009 USA, [mailto:service@agu.org], [URL:http://www.agu.org] VL - 112 IS - D17 SN - 2169-897X, 2169-897X KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Citation No. D18301 KW - trends KW - dry deposition KW - wet deposition. KW - 0312 Atmospheric Composition and Structure: Air/sea constituent fluxes (3339 KW - 4504) KW - 0300 Atmospheric Composition and Structure KW - 0345 Atmospheric Composition and Structure: Pollution: urban and regional (0305 KW - 0478 KW - 4251) KW - 0305 Atmospheric Composition and Structure: Aerosols and particles (0345 KW - 4801 KW - 4906) KW - 0335 Atmospheric Composition and Structure: Ion chemistry of the atmosphere (2419 KW - 2427) KW - 0365 Atmospheric Composition and Structure: Troposphere: composition and chemistry. KW - Pollution monitoring KW - Atmospheric pollution KW - Rainfall KW - Velocity KW - Air quality KW - Precipitation KW - USA KW - Pollutant deposition KW - Sulfur dioxide KW - Emissions KW - Emission measurements KW - Seasonal variability KW - Dry deposition KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20551189?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research.+Atmospheres&rft.atitle=Changes+in+air+quality+and+atmospheric+deposition+in+the+eastern+United+States%3A+1990-2004&rft.au=Sickles+II%2C+Joseph+E%3BShadwick%2C+Douglas+S&rft.aulast=Sickles+II&rft.aufirst=Joseph&rft.date=2007-10-01&rft.volume=112&rft.issue=D17&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research.+Atmospheres&rft.issn=2169897X&rft_id=info:doi/10.1029%2F2006JD007843 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution; Seasonal variability; Air quality; Precipitation; Dry deposition; Pollution monitoring; Pollutant deposition; Sulfur dioxide; Rainfall; Emission measurements; Emissions; Velocity; USA DO - http://dx.doi.org/10.1029/2006JD007843 ER - TY - JOUR T1 - Seasonal and regional air quality and atmospheric deposition in the eastern United States AN - 20549671; 7635003 AB - The atmospheric concentration, wet deposition, and inferred dry deposition of selected air pollutants reported over two 5-year periods in the 1990s at or near 34 rural Clean Air Status and Trends Network (CASTNET) sites located in the eastern United States (U.S.) are adjusted for known biases, composed into seasonal values, and examined. Several terms are defined for the current study, where OxN is the measured oxidized nitrogen (i.e., airborne OxN is the sum of airborne HNO sub(3) and NO sub(3) super(-), expressed as nitrogen), NH sub(4) is the measured reduced nitrogen (i.e., airborne NH sub(4) is the aerosol NH sub(4) super(+), expressed as nitrogen), N is the sum of measured oxidized and reduced forms of nitrogen, expressed as nitrogen, and S is the measured oxidized sulfur (i.e., airborne S is the sum of airborne SO sub(2) and SO sub(4) super(2-), expressed as sulfur). The atmospheric NH sub(3) concentration is not monitored in the current study. Similar patterns of seasonal and regional behavior are found consistently in both periods. In the east, atmospheric concentration, estimated deposition velocity, precipitation rate, inferred dry deposition, wet deposition, and total (dry plus wet) deposition estimates of each of the monitored chemical constituents display regular seasonal cycles of behavior. High and low seasonal values occur in summer and winter, respectively, for atmospheric concentration and dry deposition of SO sub(4) super(2-), NH sub(4) super(+), O sub(3), HNO sub(3), and N; for dry OxN deposition; for wet S and H super(+) deposition; and for total OxN and N deposition. In contrast, high seasonal values of SO sub(2) concentration and dry deposition, and atmospheric NO sub(3) super(-) concentration occur in winter. In the east, SO sub(2) composes a major portion ([sim]70%) of the atmospheric S concentration and is the dominant (>85%) contributor to dry S deposition. Although aerosol NH sub(4) super(+) represents a major portion of the measured atmospheric N concentration ([sim]67%), HNO sub(3) dominates estimates of both dry OxN (>90%) and N (>75%) deposition. Dry deposition contributes [sim]15%, 38%, and 43% to total deposition of NH sub(4), OxN, and S, and these appear to be conservative estimates. Wet deposition is a major contributor to total deposition, generally peaking in summer or spring. Total S, OxN, and N deposition peak in summer. Although mean O sub(3) concentration is [sim]70% larger in summer than winter, dry O sub(3) deposition estimates in the east are >5 times higher in summer. Within the uncertainty of current conservative estimates, dry deposition of SO sub(4) super(2-), HNO sub(3), OxN, N, and O sub(3) appears to be highest at the high-elevation subset of sites. This underscores the potential importance of dry deposition as a stressor to high-elevation ecosystems in the eastern U.S. JF - Journal of Geophysical Research. Atmospheres AU - Sickles II, Joseph E AU - Shadwick, Douglas S AD - Landscape Characterization Branch, Environmental Sciences Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA Y1 - 2007/10// PY - 2007 DA - Oct 2007 PB - American Geophysical Union, 2000 Florida Ave., N.W. Washington DC 20009 USA, [mailto:service@agu.org], [URL:http://www.agu.org] VL - 112 IS - D17 SN - 2169-897X, 2169-897X KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Citation No. D18302 KW - dry deposition KW - wet deposition KW - total deposition. KW - 0305 Atmospheric Composition and Structure: Aerosols and particles (0345 KW - 4801 KW - 4906) KW - 0312 Atmospheric Composition and Structure: Air/sea constituent fluxes (3339 KW - 4504) KW - 0335 Atmospheric Composition and Structure: Ion chemistry of the atmosphere (2419 KW - 2427) KW - 0345 Atmospheric Composition and Structure: Pollution: urban and regional (0305 KW - 0478 KW - 4251) KW - 0365 Atmospheric Composition and Structure: Troposphere: composition and chemistry. KW - Sulfur KW - Sulfur in aerosols KW - Ecosystems KW - Sulfur in atmosphere KW - Air quality KW - Sulfur dioxide KW - Ozone concentration KW - Seasonal variations KW - Ozone KW - Aerosols KW - Atmospheric pollution KW - Velocity KW - Wet deposition KW - Precipitation KW - Air pollution KW - USA KW - Pollutant deposition KW - winter KW - summer KW - Dry deposition KW - Nitrogen KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20549671?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research.+Atmospheres&rft.atitle=Seasonal+and+regional+air+quality+and+atmospheric+deposition+in+the+eastern+United+States&rft.au=Sickles+II%2C+Joseph+E%3BShadwick%2C+Douglas+S&rft.aulast=Sickles+II&rft.aufirst=Joseph&rft.date=2007-10-01&rft.volume=112&rft.issue=D17&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research.+Atmospheres&rft.issn=2169897X&rft_id=info:doi/10.1029%2F2006JD008356 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Sulfur in aerosols; Atmospheric pollution; Ecosystems; Sulfur in atmosphere; Ozone concentration; Air quality; Precipitation; Wet deposition; Dry deposition; Ozone; Sulfur; Aerosols; Velocity; Air pollution; Pollutant deposition; Sulfur dioxide; winter; summer; Seasonal variations; Nitrogen; USA DO - http://dx.doi.org/10.1029/2006JD008356 ER - TY - JOUR T1 - Adequacy of visually classified particle count statistics from regional stream habitat surveys AN - 20546129; 7626247 AB - Streamlined sampling procedures must be used to achieve a sufficient sample size with limited resources in studies undertaken to evaluate habitat status and potential management-related habitat degradation at a regional scale. At the same time, these sampling procedures must achieve sufficient precision to answer science and policy-relevant questions with an acceptable and statistically quantifiable level of uncertainty. In this paper, we examine precision and sources of error in streambed substrate characterization using data from the Environmental Monitoring and Assessment Program (EMAP) of the U.S. Environmental Protection Agency, which uses a modified "pebble count" method in which particle sizes are visually estimated rather than measured. While the coarse (2 Phi ) size classes used in EMAP have little effect on the precision of estimated geometric mean (D sub(gm)) or median (D sub(50)) particle diameter, variable classification bias among observers can contribute as much as 0.3 Phi , or about 15-20%, to the root-mean-square error (RMSE) of D sub(gm) or D sub(50) estimates. D sub(gm) and D sub(50) estimates based on EMAP data are nearly equal when fine sediments (<2 mm) are excluded, but otherwise can differ by up to a factor of 2 or more, with D sub(gm) < D sub(50) for gravel-bed streams. The RMSE of reach-scale particle size estimates based on visually classified particle count data from EMAP surveys, including variability associated with reoccupying unmarked sample reaches during revisits, is up to five to seven times higher than that reported for traditional measured pebble counts by multiple observers at a plot scale. Nonetheless, a variance partitioning analysis shows that the ratio of among site to revisit variance for several EMAP substrate metrics exceeds 8 for many potential regions of interest, suggesting that the data have adequate precision to be useful in regional assessments of channel morphology, habitat quality, or ecological condition. JF - Journal of the American Water Resources Association AU - Faustini, J M AU - Kaufmann, PR AD - Department of Fisheries and Wildlife, Oregon State University, Corvallis, Oregon 97331, USA, faustini.john@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 1293 EP - 1315 VL - 43 IS - 5 SN - 1093-474X, 1093-474X KW - Aqualine Abstracts; Sustainability Science Abstracts; Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Water Resources Abstracts KW - Particle Size KW - Particulates KW - Freshwater KW - Streams KW - Assessments KW - Classification KW - Substrates KW - Sampling KW - Particle size KW - Biological surveys KW - Rivers KW - Environmental monitoring KW - Surveys KW - Errors KW - Habitat KW - Environmental protection KW - Methodology KW - Channels KW - EPA KW - USA KW - Aquatic Habitats KW - Precision KW - Morphology KW - Q1 08382:Ecological techniques and apparatus KW - AQ 00007:Industrial Effluents KW - M3 1010:Issues in Sustainable Development KW - P 2000:FRESHWATER POLLUTION KW - SW 0835:Streamflow and runoff KW - Q5 08521:Mechanical and natural changes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20546129?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Water+Resources+Association&rft.atitle=Adequacy+of+visually+classified+particle+count+statistics+from+regional+stream+habitat+surveys&rft.au=Faustini%2C+J+M%3BKaufmann%2C+PR&rft.aulast=Faustini&rft.aufirst=J&rft.date=2007-10-01&rft.volume=43&rft.issue=5&rft.spage=1293&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Water+Resources+Association&rft.issn=1093474X&rft_id=info:doi/10.1111%2Fj.1752-1688.2007.00114.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Rivers; Biological surveys; Classification; Habitat; Environmental protection; Methodology; Channels; Particle size; EPA; Morphology; Particulates; Assessments; Aquatic Habitats; Particle Size; Precision; Substrates; Surveys; Sampling; Errors; Streams; USA; Freshwater DO - http://dx.doi.org/10.1111/j.1752-1688.2007.00114.x ER - TY - JOUR T1 - The toxic release inventory: Fact or fiction? A case study of the primary aluminum industry AN - 20503365; 7551612 AB - Since 1989 manufacturing facilities across the USA must report toxic chemical emissions to the EPA's toxic release inventory (TRI). Public release of this information and increased public scrutiny are believed to significantly contribute to the over 45% reduction in toxic chemical releases since inception of the program and to growing support for this type of informational regulation instead of traditional command-and-control. However, prior research indicates a tendency to under-report emissions. We find specific evidence of under-reporting of polycyclic aromatic hydrocarbons (PAH) to the TRI by primary aluminum facilities after promulgation of the industry's maximum available control technology (MACT) standard in 1997. We also find evidence of dislocation of emission overseas due to these regulatory requirements. Additionally, changes in energy prices affected aluminum production and further distort reported PAH emissions levels. This suggests the possibility of more widespread under-reporting that is modulated by various factors, including market conditions and new regulations, and which may partially explain the downward trend in TRI emissions. It also suggests that the quality of TRI data may improve once facilities are subject to monitoring of emissions of a TRI listed pollutant due to command-and-control regulation. JF - Journal of Environmental Management AU - Koehler, DA AU - Spengler, J D AD - 677 Huntington Ave., Boston, MA 02115, USA, Koehler.dinah@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 296 EP - 307 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 85 IS - 2 SN - 0301-4797, 0301-4797 KW - Toxicology Abstracts; Pollution Abstracts; Sustainability Science Abstracts; Ecology Abstracts KW - Manufacturing industry KW - Inventories KW - Polycyclic aromatic hydrocarbons KW - Data processing KW - case studies KW - EPA KW - USA KW - Pollutants KW - Dislocation KW - Energy KW - Aluminum KW - Emissions KW - polycyclic aromatic hydrocarbons KW - Technology KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development KW - X 24360:Metals KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20503365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Management&rft.atitle=The+toxic+release+inventory%3A+Fact+or+fiction%3F+A+case+study+of+the+primary+aluminum+industry&rft.au=Koehler%2C+DA%3BSpengler%2C+J+D&rft.aulast=Koehler&rft.aufirst=DA&rft.date=2007-10-01&rft.volume=85&rft.issue=2&rft.spage=296&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Management&rft.issn=03014797&rft_id=info:doi/10.1016%2Fj.jenvman.2006.09.025 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Inventories; Polycyclic aromatic hydrocarbons; Data processing; Dislocation; Pollutants; Energy; Aluminum; case studies; Manufacturing industry; EPA; Emissions; polycyclic aromatic hydrocarbons; Technology; USA DO - http://dx.doi.org/10.1016/j.jenvman.2006.09.025 ER - TY - JOUR T1 - Characterizing Uncertainty and Variability in Physiologically Based Pharmacokinetic Models: State of the Science and Needs for Research and Implementation AN - 20335695; 7617541 AB - Physiologically based pharmacokinetic (PBPK) models are used in mode-of-action based risk and safety assessments to estimate internal dosimetry in animals and humans. When used in risk assessment, these models can provide a basis for extrapolating between species, doses, and exposure routes or for justifying nondefault values for uncertainty factors. Characterization of uncertainty and variability is increasingly recognized as important for risk assessment; this represents a continuing challenge for both PBPK modelers and users. Current practices show significant progress in specifying deterministic biological models and nondeterministic (often statistical) models, estimating parameters using diverse data sets from multiple sources, using them to make predictions, and characterizing uncertainty and variability of model parameters and predictions. The International Workshop on Uncertainty and Variability in PBPK Models, held 31 Oct-2 Nov 2006, identified the state-of-the-science, needed changes in practice and implementation, and research priorities. For the short term, these include (1) multidisciplinary teams to integrate deterministic and nondeterministic/statistical models; (2) broader use of sensitivity analyses, including for structural and global (rather than local) parameter changes; and (3) enhanced transparency and reproducibility through improved documentation of model structure(s), parameter values, sensitivity and other analyses, and supporting, discrepant, or excluded data. Longer-term needs include (1) theoretical and practical methodological improvements for nondeterministic/statistical modeling; (2) better methods for evaluating alternative model structures; (3) peer-reviewed databases of parameters and covariates, and their distributions; (4) expanded coverage of PBPK models across chemicals with different properties; and (5) training and reference materials, such as cases studies, bibliographies/glossaries, model repositories, and enhanced software. The multidisciplinary dialogue initiated by this Workshop will foster the collaboration, research, data collection, and training necessary to make characterizing uncertainty and variability a standard practice in PBPK modeling and risk assessment. JF - Toxicological Sciences AU - Barton, Hugh A AU - Chiu, Weihsueh A AU - Woodrow Setzer, R AU - Andersen, Melvin E AU - Bailer, AJohn AU - Bois, Frederic Y AU - DeWoskin, Robert S AU - Hays, Sean AU - Johanson, Gunnar AU - Jones, Nancy AU - Loizou, George AU - MacPhail, Robert C AU - Portier, Christopher J AU - Spendiff, Martin AU - Tan, Yu-Mei AD - US EPA, ORD, National Center for Computational Toxicology, RTP, North Carolina 27711, USA Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 395 EP - 402 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 99 IS - 2 SN - 1096-6080, 1096-6080 KW - Health & Safety Science Abstracts; Toxicology Abstracts KW - Chemicals KW - Risk assessment KW - Data collection KW - Mathematical models KW - Training KW - Dosimetry KW - Statistical analysis KW - Data collections KW - Pharmacokinetics KW - transparency KW - case studies KW - Computer programs KW - software KW - Bibliographies KW - sensitivity analysis KW - H 14000:Toxicology KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20335695?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Characterizing+Uncertainty+and+Variability+in+Physiologically+Based+Pharmacokinetic+Models%3A+State+of+the+Science+and+Needs+for+Research+and+Implementation&rft.au=Barton%2C+Hugh+A%3BChiu%2C+Weihsueh+A%3BWoodrow+Setzer%2C+R%3BAndersen%2C+Melvin+E%3BBailer%2C+AJohn%3BBois%2C+Frederic+Y%3BDeWoskin%2C+Robert+S%3BHays%2C+Sean%3BJohanson%2C+Gunnar%3BJones%2C+Nancy%3BLoizou%2C+George%3BMacPhail%2C+Robert+C%3BPortier%2C+Christopher+J%3BSpendiff%2C+Martin%3BTan%2C+Yu-Mei&rft.aulast=Barton&rft.aufirst=Hugh&rft.date=2007-10-01&rft.volume=99&rft.issue=2&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Computer programs; software; Mathematical models; Bibliographies; Dosimetry; Statistical analysis; Data collections; Pharmacokinetics; case studies; transparency; Chemicals; Data collection; Training; sensitivity analysis ER - TY - JOUR T1 - Conservation and economic viability of nature reserves: An emergy evaluation of the Yancheng Biosphere Reserve AN - 20326526; 7637320 AB - Evaluating the ecological and economic benefits of nature reserves in a fair way is a difficult problem confronting not only conservation scientists and managers but also governments and private land owners. Nature reserves and other social and economic land uses must be evaluated on an objective basis to provide an accurate measure of relative benefits for decision-making. The ecological and economic benefits of various land uses can be expressed in equivalent terms using emergy as a common denominator. Emergy synthesis is a biophysical, donor-based method of valuation that we used to assess the ecological-economic system of the Yancheng Biosphere Reserve (YBR) in North Jiangsu Province, China. In this paper, we introduce new emergy measures designed especially to capture the conservation value of natural lands, as well as a measure of the economic viability of nature reserves. The network structure of natural resources, economic production, and conservation activities in Yancheng reserve was examined and compared to the Maipo Nature Reserve (MNR) in Hong Kong, and a salt marsh ecological-engineering system also in Yancheng. This study showed that there is about a 10:1 return on the emergy invested by government in operating the Yancheng Biosphere Reserve, which is a major migratory stop-over and wintering site for the endangered red-crowned crane (Grus japonensis). Only 2.2% of the support for conservation in YBR comes from the private sector compared to 41.4% for MNR. One way to improve social self-sufficiency of the reserve is to develop ecotourism and private donors, which will increase economic vitality and mitigate the intense economic competition for reserve land. JF - Biological Conservation AU - Lu, H AU - Campbell, D AU - Chen, J AU - Qin, P AU - Ren, H AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Atlantic Ecology Division, 27 Tarzwell Drive, Narragansett, RI, USA, luhf@scbg.ac.cn Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 415 EP - 438 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 139 IS - 3-4 SN - 0006-3207, 0006-3207 KW - Sustainability Science Abstracts; Ecology Abstracts KW - Biosphere reserves KW - Salt marshes KW - Economics KW - Recruitment KW - Grus japonensis KW - Conservation KW - Nature reserves KW - Competition KW - Land use KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20326526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Conservation&rft.atitle=Conservation+and+economic+viability+of+nature+reserves%3A+An+emergy+evaluation+of+the+Yancheng+Biosphere+Reserve&rft.au=Lu%2C+H%3BCampbell%2C+D%3BChen%2C+J%3BQin%2C+P%3BRen%2C+H&rft.aulast=Lu&rft.aufirst=H&rft.date=2007-10-01&rft.volume=139&rft.issue=3-4&rft.spage=415&rft.isbn=&rft.btitle=&rft.title=Biological+Conservation&rft.issn=00063207&rft_id=info:doi/10.1016%2Fj.biocon.2007.07.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-11-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Biosphere reserves; Salt marshes; Recruitment; Economics; Conservation; Nature reserves; Competition; Land use; Grus japonensis DO - http://dx.doi.org/10.1016/j.biocon.2007.07.014 ER - TY - JOUR T1 - Serologic evaluation of human microcystin exposure AN - 20303051; 7595642 AB - Microcystins are among the most commonly detected toxins associated with cyanobacteria blooms worldwide. Two episodes of intravenous microcystin exposures occurred among kidney dialysis patients during 1996 and 2001. Analysis of serum samples collected during these episodes suggests that microcystins are detectable as free and bound forms in human serum. Our goal was to characterize the biochemical evidence for human exposure to microcystins, to identify uncertainties associated with interpretation of these observed results, and to identify research needs. We analyzed serum samples using enzyme-linked immunosorbent assay (ELISA) methods to detect free microcystins, and gas chromatography/mass spectrometry (GC/MS) to detect 2-methyl-3-methoxy-4-phenylbutyric acid (MMPB). MMPB is derived from both free and protein-bound microcystins by chemical oxidation, and it appears to represent total microcystins present in serum. We found evidence of free microcystins in patient serum for more than 50 days after the last documented exposure. Serum concentrations of free microcystins were consistently lower than MMPB quantification of total microcystins: free microcystins as measured by ELISA were only 8-51% of total microcystin concentrations as detected by the GC/MS method. After intravenous exposure episodes, we found evidence of microcystins in human serum in free and protein-bound forms, though the nature of the protein-bound forms is uncertain. Free microcystins appear to be a small but variable subset of total microcystins present in human serum. Research is needed to elucidate the human toxicokinetics of microcystins, in part to determine how observed serum concentrations can be used to estimate previous microcystin exposure. JF - Environmental Toxicology AU - Hilborn, E D AU - Carmichael, W W AU - Soares, R M AU - Yuan, M AU - Servaites, J C AU - Barton, H A AU - Azevedo, S M F O AD - United States Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina, hilborn.e@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 459 EP - 463 PB - John Wiley & Sons, 111 River Street Hoboken NJ 07030 USA, [mailto:custserv@wiley.com], [URL:http://www.wiley.com/] VL - 22 IS - 5 SN - 1520-4081, 1520-4081 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Toxicology Abstracts KW - Enzyme-linked immunosorbent assay KW - Intravenous administration KW - Dialysis KW - Gas chromatography KW - Microcystins KW - Oxidation KW - Mass spectroscopy KW - Toxins KW - X 24370:Natural Toxins KW - K 03400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20303051?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology&rft.atitle=Serologic+evaluation+of+human+microcystin+exposure&rft.au=Hilborn%2C+E+D%3BCarmichael%2C+W+W%3BSoares%2C+R+M%3BYuan%2C+M%3BServaites%2C+J+C%3BBarton%2C+H+A%3BAzevedo%2C+S+M+F+O&rft.aulast=Hilborn&rft.aufirst=E&rft.date=2007-10-01&rft.volume=22&rft.issue=5&rft.spage=459&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology&rft.issn=15204081&rft_id=info:doi/10.1002%2Ftox.20287 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Dialysis; Intravenous administration; Enzyme-linked immunosorbent assay; Gas chromatography; Microcystins; Oxidation; Toxins; Mass spectroscopy DO - http://dx.doi.org/10.1002/tox.20287 ER - TY - JOUR T1 - Evaluating virulence of waterborne and clinical Aeromonas isolates using gene expression and mortality in neonatal mice followed by assessing cell culture's ability to predict virulence based on transcriptional response AN - 20138819; 7992341 AB - Aims: To assess the virulence of Aeromonas spp. using two models, a neonatal mouse assay and a mouse intestinal cell culture. Methods and Results: After artificial infection with a variety of Aeromonas spp., mRNA extracts from the two models were processed and hydridized to murine microarrays to determine host gene response. Definition of virulence was determined based on host mRNA production in murine neonatal intestinal tissue and mortality of infected animals. Infections of mouse intestinal cell cultures were then performed to determine whether this simpler model system's mRNA responses correlated to neonatal results and therefore be predictive of virulence of Aeromonas spp. Virulent aeromonads up-regulated transcripts in both models including multiple host defense gene products (chemokines, regulation of transcription and apoptosis and cell signalling). Avirulent species exhibited little or no host response in neonates. Mortality results correlated well with both bacterial dose and average fold change of up-regulated transcripts in the neonatal mice. Conclusions: Cell culture results were less discriminating but showed promise as potentially being able to be predictive of virulence. Jun oncogene up-regulation in murine cell culture is potentially predictive of Aeromonas virulence. Significance and Impact of the Study: Having the ability to determine virulence of waterborne pathogens quickly would potentially assist public health officials to rapidly assess exposure risks. JF - Journal of Applied Microbiology AU - Hayes, S L AU - Rodgers, M R AU - Lye, D J AU - Stelma, G N AU - McKinstry, CA AU - Malard, J M AU - Vesper, S J AD - USEPA, National Risk Management Research Laboratory, Water Supply-Water Resources Division, Cincinnati, OH, USA, hayes.sam@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 811 EP - 820 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 103 IS - 4 SN - 1364-5072, 1364-5072 KW - Genetics Abstracts; Biotechnology and Bioengineering Abstracts; Microbiology Abstracts B: Bacteriology KW - Aeromonas KW - gene expression KW - host response KW - virulence KW - Mortality KW - Chemokines KW - Apoptosis KW - Animal models KW - Transcription KW - Cell culture KW - Pathogens KW - Infection KW - DNA microarrays KW - Public health KW - Gene expression KW - Virulence KW - Oncogenes KW - Intestine KW - Neonates KW - Signal transduction KW - J 02310:Genetics & Taxonomy KW - W 30945:Fermentation & Cell Culture KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20138819?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Microbiology&rft.atitle=Evaluating+virulence+of+waterborne+and+clinical+Aeromonas+isolates+using+gene+expression+and+mortality+in+neonatal+mice+followed+by+assessing+cell+culture%27s+ability+to+predict+virulence+based+on+transcriptional+response&rft.au=Hayes%2C+S+L%3BRodgers%2C+M+R%3BLye%2C+D+J%3BStelma%2C+G+N%3BMcKinstry%2C+CA%3BMalard%2C+J+M%3BVesper%2C+S+J&rft.aulast=Hayes&rft.aufirst=S&rft.date=2007-10-01&rft.volume=103&rft.issue=4&rft.spage=811&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Microbiology&rft.issn=13645072&rft_id=info:doi/10.1111%2Fj.1365-2672.2007.03318.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Mortality; Chemokines; Apoptosis; Animal models; Transcription; Cell culture; Pathogens; Infection; DNA microarrays; Public health; Virulence; Gene expression; Oncogenes; Intestine; Neonates; Signal transduction; Aeromonas DO - http://dx.doi.org/10.1111/j.1365-2672.2007.03318.x ER - TY - JOUR T1 - Comparative global transcription analysis of sodium hypochlorite, peracetic acid, and hydrogen peroxide on Pseudomonas aeruginosa AN - 20031754; 7969989 AB - Disinfectants are routinely used in hospitals and health care facilities for surface sterilization. However, the mechanisms by which these disinfectants kill and the extent to which bacteria, including Pseudomonas aeruginosa, are resistant remains unclear. Consequently, P. aeruginosa nosocomial infections result in considerable casualties and economic hardship. Previously, DNA microarrays were utilized to analyze the genome-wide transcription changes in P. aeruginosa after oxidative antimicrobial (sodium hypochlorite, peracetic acid, and hydrogen peroxide) exposure. Simultaneous analysis of these transcriptome datasets provided a comprehensive understanding of the differential responses to these disinfectants. An analysis of variance, functional classification analysis, metabolic pathway analysis, Venn diagram analysis, and principal component analysis revealed that sodium hypochlorite exposure resulted in more genome-wide changes than either peracetic acid or hydrogen peroxide exposures. JF - Applied Microbiology and Biotechnology AU - Small, David A AU - Chang, Wook AU - Toghrol, Freshteh AU - Bentley, William E AD - US Environmental Protection Agency, Fort Meade, MD, 20755, USA, toghrol.freshteh@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 1093 EP - 1105 PB - Springer-Verlag, Heidelberger Platz 3 Berlin 14197 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 76 IS - 5 SN - 0175-7598, 0175-7598 KW - Microbiology Abstracts B: Bacteriology; Biochemistry Abstracts 2: Nucleic Acids; Biotechnology and Bioengineering Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Sodium hypochlorite KW - Transcription KW - DNA microarrays KW - Sterilization KW - Antimicrobial agents KW - Gene expression KW - Disinfectants KW - Classification KW - Hydrogen peroxide KW - Principal components analysis KW - Nosocomial infection KW - Economics KW - Peracetic acid KW - Metabolic pathways KW - Pseudomonas aeruginosa KW - Hospitals KW - A 01310:Products of Microorganisms KW - J 02400:Human Diseases KW - W 30915:Pharmaceuticals & Vaccines KW - N 14810:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20031754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Microbiology+and+Biotechnology&rft.atitle=Comparative+global+transcription+analysis+of+sodium+hypochlorite%2C+peracetic+acid%2C+and+hydrogen+peroxide+on+Pseudomonas+aeruginosa&rft.au=Small%2C+David+A%3BChang%2C+Wook%3BToghrol%2C+Freshteh%3BBentley%2C+William+E&rft.aulast=Small&rft.aufirst=David&rft.date=2007-10-01&rft.volume=76&rft.issue=5&rft.spage=1093&rft.isbn=&rft.btitle=&rft.title=Applied+Microbiology+and+Biotechnology&rft.issn=01757598&rft_id=info:doi/10.1007%2Fs00253-007-1072-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Sodium hypochlorite; Transcription; DNA microarrays; Sterilization; Antimicrobial agents; Gene expression; Disinfectants; Classification; Hydrogen peroxide; Principal components analysis; Peracetic acid; Economics; Nosocomial infection; Metabolic pathways; Hospitals; Pseudomonas aeruginosa DO - http://dx.doi.org/10.1007/s00253-007-1072-z ER - TY - JOUR T1 - A novel cadherin-like gene from western corn rootworm, Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae), larval midgut tissue AN - 19883090; 7991592 AB - A cadherin-like gene associated with larval midgut tissues was cloned from western corn rootworm (Diabrotica virgifera virgifera: Coleoptera), an economically important agricultural pest in North America and Europe and the primary target pest species for corn hybrids expressing Cry3 toxins from Bacillus thuringiensis (Bt). The full-length cDNA (5371 bp in length) encodes an open reading frame for a 1688 amino acid polypeptide. The putative protein has similar architecture to cadherin-like proteins isolated from lepidopteran midguts that have been shown to bind to Cry1 Bt toxins and have been implicated in Bt resistance. The D. v. virgifera cadherin-like gene is expressed primarily in the larval midgut and regulated during development, with high levels of expression observed in all instars and adults but not pupae. The corresponding genomic sequence spans more than 90 kb and is interspersed with 30 large introns. The genomic organization of the cadherin-like gene for this coleopteran species bears strong resemblance to lepidopteran cadherins suggesting a common molecular basis for susceptibility to Cry3 toxins in Coleoptera. JF - Insect Molecular Biology AU - Sayed, A AU - Nekl, E R AU - Siqueira, HAA AU - Wang, H-C AU - ffrench-Constant, R H AU - Bagley, M AU - Siegfried, B D AD - Dynamac Corporation, c/o US EPA, Cincinnati, OH, USA; , sayed.abu@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 591 EP - 600 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 16 IS - 5 SN - 0962-1075, 0962-1075 KW - Microbiology Abstracts B: Bacteriology; Biochemistry Abstracts 2: Nucleic Acids; Genetics Abstracts; Entomology Abstracts KW - cadherin KW - Diabrotica KW - Bt receptor KW - insect midgut KW - exon KW - intron KW - Amino acids KW - Coleoptera KW - Bacillus thuringiensis KW - Toxins KW - Lepidoptera KW - Cadherin KW - Hybrids KW - Introns KW - Midgut KW - genomics KW - Pests KW - Open reading frames KW - Chrysomelidae KW - Diabrotica virgifera virgifera KW - N 14815:Nucleotide Sequence KW - G 07800:Plants and Algae KW - Z 05360:Genetics and Evolution KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19883090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Insect+Molecular+Biology&rft.atitle=A+novel+cadherin-like+gene+from+western+corn+rootworm%2C+Diabrotica+virgifera+virgifera+%28Coleoptera%3A+Chrysomelidae%29%2C+larval+midgut+tissue&rft.au=Sayed%2C+A%3BNekl%2C+E+R%3BSiqueira%2C+HAA%3BWang%2C+H-C%3Bffrench-Constant%2C+R+H%3BBagley%2C+M%3BSiegfried%2C+B+D&rft.aulast=Sayed&rft.aufirst=A&rft.date=2007-10-01&rft.volume=16&rft.issue=5&rft.spage=591&rft.isbn=&rft.btitle=&rft.title=Insect+Molecular+Biology&rft.issn=09621075&rft_id=info:doi/10.1111%2Fj.1365-2583.2007.00755.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Amino acids; Hybrids; Cadherin; Introns; Pests; genomics; Midgut; Open reading frames; Toxins; Coleoptera; Bacillus thuringiensis; Lepidoptera; Diabrotica virgifera virgifera; Chrysomelidae DO - http://dx.doi.org/10.1111/j.1365-2583.2007.00755.x ER - TY - JOUR T1 - Enhanced concentration and isolation of Cyclospora cayetanensis oocysts from human fecal samples AN - 19879468; 7734772 AB - Cyclospora cayetanensis is the causative agent of cyclosporiasis, an emerging infectious disease. We present a new method for the purification of C. cayetanensis oocysts from feces using a modified detachment solution and Renocal-sucrose gradient sedimentation. This method yields oocysts free from adherent fecal debris and amenable to processing using flow cytometry. JF - Journal of Microbiological Methods AU - Riner, D K AU - Mullin, A S AU - Lucas, SY AU - Cross, J H AU - Lindquist, HDA AD - 26 W. Martin Luther King Dr. Cincinnati, OH 45268, United States, lindquist.alan@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 75 EP - 77 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 71 IS - 1 SN - 0167-7012, 0167-7012 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Biotechnology and Bioengineering Abstracts KW - Flow cytometry KW - Cyclospora cayetanensis KW - Oocysts KW - Infectious diseases KW - Cyclosporiasis KW - Purification KW - Sedimentation KW - Feces KW - K 03300:Methods KW - W 30900:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19879468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=Enhanced+concentration+and+isolation+of+Cyclospora+cayetanensis+oocysts+from+human+fecal+samples&rft.au=Riner%2C+D+K%3BMullin%2C+A+S%3BLucas%2C+SY%3BCross%2C+J+H%3BLindquist%2C+HDA&rft.aulast=Riner&rft.aufirst=D&rft.date=2007-10-01&rft.volume=71&rft.issue=1&rft.spage=75&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2007.06.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Flow cytometry; Infectious diseases; Oocysts; Purification; Cyclosporiasis; Feces; Sedimentation; Cyclospora cayetanensis DO - http://dx.doi.org/10.1016/j.mimet.2007.06.021 ER - TY - JOUR T1 - An integrated culture and real-time PCR method to assess viability of disinfectant treated Bacillus spores using robotics and the MPN quantification method AN - 19879378; 7734739 AB - Using robotics and the MPN technique, a 96-microwell method was developed to compare two procedures for enumeration of viable chlorine-treated B. atrophaeus spores: broth-culture enrichment followed by real-time polymerase chain reaction analysis; and filter plating on agar. Recoveries of chlorine-treated spores were improved by broth enrichment over filter plating, whereas recoveries of non-treated spores were not different in the two procedures. JF - Journal of Microbiological Methods AU - Varughese, E A AU - Wymer, L J AU - Haugland, R A AD - U.S. Environmental Protection Agency, 26 W. Martin Luther King, Cincinnati, OH 45268, United States, varughese.eunice@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 66 EP - 70 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 71 IS - 1 SN - 0167-7012, 0167-7012 KW - Microbiology Abstracts B: Bacteriology; Biotechnology and Bioengineering Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Filters KW - Agar KW - Disinfectants KW - Polymerase chain reaction KW - robotics KW - Spores KW - Bacillus KW - W 30900:Methods KW - A 01300:Methods KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19879378?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=An+integrated+culture+and+real-time+PCR+method+to+assess+viability+of+disinfectant+treated+Bacillus+spores+using+robotics+and+the+MPN+quantification+method&rft.au=Varughese%2C+E+A%3BWymer%2C+L+J%3BHaugland%2C+R+A&rft.aulast=Varughese&rft.aufirst=E&rft.date=2007-10-01&rft.volume=71&rft.issue=1&rft.spage=66&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2007.07.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Filters; Agar; Disinfectants; Polymerase chain reaction; robotics; Spores; Bacillus DO - http://dx.doi.org/10.1016/j.mimet.2007.07.011 ER - TY - JOUR T1 - Rainbow Trout (Oncorhynchus mykiss) and Brook Trout (Salvelinus fontinalis) 7-Day Survival and Growth Test Method AN - 19736240; 7623469 AB - A short-term method was developed in this study for conducting subchronic survival and growth renewal toxicity tests with rainbow trout (Oncorhynchus mykiss) and brook trout (Salvelinus fontinalis). Previously published early life-stage methods for various salmonid species involve test durations of 30 to 90 days. This trout method, however, follows a previously published 7-day fathead minnow (Pimephales promelas) growth method. The tests performed in this study measured subchronic growth and survival effects using standard reference toxicants (ammonium chloride, potassium chloride, phenol, and zinc sulfate), receiving water, and effluent samples. The test results were compared with performance criteria and results for 7-day survival and growth tests with P. promelas to determine the level of comparability between the two species. The results from tests with both salmonid species indicated that this 7-day survival and growth test method using O. mykiss and S. fontinalis provides reproducible results with various reference toxicant materials and can be used successfully to detect potential toxicity in environmental samples. JF - Archives of Environmental Contamination and Toxicology AU - Lazorchak, James M AU - Smith, Mark E AD - Office of Research and Development, National Exposure Research Laboratory, 26 West Martin Luther King Drive, Cincinnati, OH, USA, lazorchak.jim@epa.gov Y1 - 2007/10// PY - 2007 DA - October 2007 SP - 397 EP - 405 PB - Springer-Verlag, 175 Fifth Ave. New York NY 10010 USA, [mailto:orders@springer-ny.com] VL - 53 IS - 3 SN - 0090-4341, 0090-4341 KW - Ecology Abstracts; Toxicology Abstracts; Pollution Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; Aqualine Abstracts KW - Sulfates KW - toxicity testing KW - Toxicants KW - Anadromous species KW - Population dynamics KW - Freshwater fish KW - Toxicity tests KW - Testing Procedures KW - Salmon KW - Ammonium KW - zinc sulfate KW - Potassium KW - Developmental stages KW - Oncorhynchus mykiss KW - Effluents KW - Trout KW - Water Pollution Effects KW - survival KW - Salvelinus fontinalis KW - Chlorides KW - Survival KW - Fontinalis KW - Growth KW - Zinc KW - Materials Testing KW - potassium chloride KW - Toxicity KW - Phenols KW - Pimephales promelas KW - Ammonium chloride KW - D 04070:Pollution KW - O 4020:Pollution - Organisms/Ecology/Toxicology KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - AQ 00008:Effects of Pollution KW - X 24360:Metals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19736240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Environmental+Contamination+and+Toxicology&rft.atitle=Rainbow+Trout+%28Oncorhynchus+mykiss%29+and+Brook+Trout+%28Salvelinus+fontinalis%29+7-Day+Survival+and+Growth+Test+Method&rft.au=Lazorchak%2C+James+M%3BSmith%2C+Mark+E&rft.aulast=Lazorchak&rft.aufirst=James&rft.date=2007-10-01&rft.volume=53&rft.issue=3&rft.spage=397&rft.isbn=&rft.btitle=&rft.title=Archives+of+Environmental+Contamination+and+Toxicology&rft.issn=00904341&rft_id=info:doi/10.1007%2Fs00244-006-0227-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Growth; Toxicants; Anadromous species; Survival; Freshwater fish; Effluents; Population dynamics; Toxicity tests; Phenols; zinc sulfate; Ammonium chloride; Developmental stages; potassium chloride; Toxicity; toxicity testing; Sulfates; Ammonium; Zinc; Chlorides; Potassium; survival; Salmon; Testing Procedures; Trout; Water Pollution Effects; Materials Testing; Fontinalis; Salvelinus fontinalis; Pimephales promelas; Oncorhynchus mykiss DO - http://dx.doi.org/10.1007/s00244-006-0227-8 ER - TY - JOUR T1 - Female-Biased Sex Ratio Arises After Parental Care in the Sexually Dimorphic Waved Albatross (Phoebastria irrorata) AN - 19716920; 8691710 AB - In response to evidence of sexual segregation at foraging grounds as well as male-biased band recoveries, we investigated the ontogeny of the female- biased adult sex ratio in the Waved Albatross (Phoebastria irrorata), an IUCN 'critically endangered species' essentially endemic to Isla Espanola, Galapagos, Ecuador. Using a molecular technique to determine the sex of chicks and adults and known fate analysis of chicks during rearing, we found no evidence of a sex-ratio bias at hatching or fledging in three consecutive years with variable reproductive success. Although male chicks were significantly larger than females at fledging, survival to fledging of a large sample of male and female chicks did not differ. The sex ratio among a cohort of young adults at approximately the age of first breeding (eight years) also did not differ significantly from parity. Differential adult mortality, including male-biased mortality in fisheries, is the most probable cause of a female- biased population sex ratio, and is at least partially responsible for an apparent reduction in the number of breeding pairs of this species. JF - Auk AU - Awkerman, Jill A AU - Westbrock, Mark A AU - Huyvaert, Kathryn P AU - Anderson, David J AD - Department of Biology, Wake Forest University, Winston-Salem, North Carolina 27109, USA, awkerman.jill@epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 1336 EP - 1346 PB - University of California Press, 2000 Center St, Ste 303 VL - 124 IS - 4 SN - 0004-8038, 0004-8038 KW - Waved albatross KW - Animal Behavior Abstracts; Ecology Abstracts; Sustainability Science Abstracts; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources KW - known fate KW - Phoebastria irrorata KW - sex ratio KW - Waved Albatross KW - bycatch KW - provision KW - seabird KW - Sexual dimorphism KW - parity KW - Age KW - Ecuador KW - Survival KW - Parental behaviour KW - young adults KW - breeding KW - Breeding KW - Fisheries KW - ISE, Ecuador KW - Ontogeny KW - Parity KW - Marine KW - Mortality KW - Marine birds KW - Sex ratio KW - hatching KW - Rare species KW - Foraging behaviour KW - Endangered species KW - Reproduction KW - Population structure KW - survival KW - Mortality causes KW - Breeding success KW - O 1070:Ecology/Community Studies KW - M3 1010:Issues in Sustainable Development KW - Y 25060:Ontogeny KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08423:Behaviour UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19716920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Auk&rft.atitle=Female-Biased+Sex+Ratio+Arises+After+Parental+Care+in+the+Sexually+Dimorphic+Waved+Albatross+%28Phoebastria+irrorata%29&rft.au=Awkerman%2C+Jill+A%3BWestbrock%2C+Mark+A%3BHuyvaert%2C+Kathryn+P%3BAnderson%2C+David+J&rft.aulast=Awkerman&rft.aufirst=Jill&rft.date=2007-10-01&rft.volume=124&rft.issue=4&rft.spage=1336&rft.isbn=&rft.btitle=&rft.title=Auk&rft.issn=00048038&rft_id=info:doi/10.1642%2F0004-8038%282007%291242.0.CO%3B2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-12-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Foraging behaviour; Marine birds; Sex ratio; Parental behaviour; Population structure; Rare species; Mortality causes; Breeding success; Parity; Sexual dimorphism; Mortality; Breeding; Endangered species; Survival; Ontogeny; Age; parity; breeding; Fisheries; hatching; Reproduction; sex ratio; survival; young adults; Phoebastria irrorata; Ecuador; ISE, Ecuador; Marine DO - http://dx.doi.org/10.1642/0004-8038(2007)124[1336:FSRAAP]2.0.CO;2 ER - TY - JOUR T1 - DNA-based methods for monitoring invasive species: a review and prospectus AN - 19676048; 7967600 AB - The recent explosion of interest in DNA-based tools for species identification has prompted widespread speculation on the future availability of inexpensive, rapid, and accurate means of identifying specimens and assessing biodiversity. One applied field that may benefit dramatically from the development of such technologies is the detection, identification, and monitoring of invasive species. Recent studies have demonstrated the feasibility of DNA-based tools for such important tasks as confirmation of specimen identity and targeted screening for known or anticipated invaders. However, significant technological hurdles must be overcome before more ambitious applications, including estimation of propagule pressure and comprehensive surveys of complex environmental samples, are to be realized. Here we review existing methods, examine the technical difficulties associated with development of more sophisticated tools, and consider the potential utility of these DNA-based technologies for various applications relevant to invasive species monitoring. JF - Biological Invasions AU - Darling, John A AU - Blum, Michael J AD - US Environmental Protection Agency, 27 West Martin Luther King Boulevard, Cincinnati, OH, 45268, USA, darling.john@epamail.epa.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 751 EP - 765 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany, [mailto:subscriptions@springer.de], [URL:http://www.springer.de/] VL - 9 IS - 7 SN - 1387-3547, 1387-3547 KW - Ecology Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Sustainability Science Abstracts KW - Propagules KW - Reviews KW - Invasions KW - Biodiversity KW - Introduced species KW - Pressure KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - N 14810:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19676048?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Invasions&rft.atitle=DNA-based+methods+for+monitoring+invasive+species%3A+a+review+and+prospectus&rft.au=Darling%2C+John+A%3BBlum%2C+Michael+J&rft.aulast=Darling&rft.aufirst=John&rft.date=2007-10-01&rft.volume=9&rft.issue=7&rft.spage=751&rft.isbn=&rft.btitle=&rft.title=Biological+Invasions&rft.issn=13873547&rft_id=info:doi/10.1007%2Fs10530-006-9079-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Propagules; Reviews; Biodiversity; Invasions; Pressure; Introduced species DO - http://dx.doi.org/10.1007/s10530-006-9079-4 ER - TY - JOUR T1 - Developing Asthma in Childhood from Exposure to Secondhand Tobacco Smoke: Insights from a Meta-Regression AN - 19522899; 7630570 AB - Objective: Studies have identified associations between household secondhand tobacco smoke (SHS) exposure and induction of childhood asthma. However, the true nature and strength of this association remains confounded in many studies, producing inconsistent evidence. To look for sources of potential bias and try to uncover consistent patterns of relative risk estimates (RRs), we conducted a meta-analysis of studies published between 1970 and 2005. Data Sources: Through an extensive literature search, we identified 38 epidemiologic studies of SHS exposure and the development of childhood asthma (that also controlled for atopy history) from 300 potentially relevant articles. Data synthesis: We observed substantial heterogeneity within initial summary RRs of 1.48 [95% confidence interval (CI), 1.32-1.65], 1.25 (1.21-1.30), and 1.21 (1.08-1.36), for ever, current, and incident asthma, respectively. Lack of control for type of atopy history (familial or child) and child's own smoking status within studies and age category altered summary RRs in separate meta-regressions. After adjusting for these confounding characteristics, consistent patterns of association emerged between SHS exposure and childhood asthma induction. Our summary RR of 1.33 (95% CI, 1.14-1.56) from studies of incident asthma among older children (6-18 years of age) is 1.27 times the estimate from studies of younger children and higher than estimates reported in earlier meta-analyses. Conclusions: This new finding indicates that exposure duration may be a more important factor in the induction of asthma than previously understood, and suggests that SHS could be a more fundamental and widespread cause of childhood asthma than some previous meta-analyses have indicated. JF - Environmental Health Perspectives AU - Vork, K L AU - Broadwin, R L AU - Blaisdell, R J AD - Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, 1515 Clay St., 16th Floor, Oakland CA 94612 USA, kvork@oehha.ca.gov Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 1394 EP - 1400 VL - 115 IS - 10 SN - 0091-6765, 0091-6765 KW - Risk Abstracts; Pollution Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts KW - Risk assessment KW - Historical account KW - Age KW - Asthma KW - Respiratory diseases KW - Children KW - Smoke KW - Smoking KW - households KW - Passive smoking KW - Atopy KW - Reviews KW - Tobacco KW - X 24380:Social Poisons & Drug Abuse KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19522899?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Developing+Asthma+in+Childhood+from+Exposure+to+Secondhand+Tobacco+Smoke%3A+Insights+from+a+Meta-Regression&rft.au=Vork%2C+K+L%3BBroadwin%2C+R+L%3BBlaisdell%2C+R+J&rft.aulast=Vork&rft.aufirst=K&rft.date=2007-10-01&rft.volume=115&rft.issue=10&rft.spage=1394&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/10.1289%2Fehp.10155 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Smoke; Smoking; Age; Atopy; Reviews; Tobacco; Asthma; Children; Historical account; households; Passive smoking; Respiratory diseases DO - http://dx.doi.org/10.1289/ehp.10155 ER - TY - JOUR T1 - Biogeography of seed-dispersal syndromes, life-forms and seed sizes among woody rain-forest plants in Australia's subtropics AN - 19463296; 7992628 AB - Aim To enhance our understanding of the evolutionary interactions between seed-dispersal syndromes, life-forms, seed size, and habitat characteristics by studying their association with the regional-scale distributions of subtropical rain-forest plants in the context of climatic gradients. Location South-east Queensland, subtropical eastern Australia (152 degree E, 26 degree S). Methods We classified 250 rain-forest sites into six floristic site-groups based on their woody plant composition. The resulting classification was strongly associated with variation in rainfall. The distribution of species across the floristic site-groups was used to assign 568 species to seven habitat classes (one class for 'widespread' species, with all other species classified according to the site-group within which they were most frequent). Species were also classified for three other categorical life-history factors: three dispersal syndromes based on diaspore morphology (fleshy, wind-assisted, and unadorned); four life-forms (trees, shrubs and small trees, tall climbers, and short and shrubby climbers); and four seed-diameter classes (< 3 mm, greater than or equal to 3 and < 4.5 mm, greater than or equal to 4.5 and < 7 mm, and greater than or equal to 7 mm). We used a basic comparative approach augmented by simple phylogenetically constrained comparisons to assess association between dispersal syndrome, seed size, life-form, and habitat class. Results Across the rain forests of south-east Queensland, the proportion of species with fleshy diaspores or of large stature increases with rainfall. High-rainfall sites also have larger average seed sizes, but the difference in average seed size between high- and low-rainfall sites is small compared with variation within sites. Among species, those with fleshy fruit tend to have larger seeds and to favour high-rainfall sites. Very few small trees produce diaspores adapted for wind-assisted dispersal. On average, species with unadorned diaspores have smaller seeds than those with fleshy diaspores. However, within sites, species with unadorned and fleshy diaspores have similar average seed sizes, and some species with unadorned diaspores from high-rainfall habitats have extremely large seeds. Main conclusions Commonly observed associations between fleshy fruit, larger plants, larger seeds, and productive habitats are apparent within the rain-forest flora of south-east Queensland. However, these associations are generally weak and involve complex interactions. For example, the strong tendency for species with fleshy fruit to have larger seeds than those with unadorned diaspores concealed a significant group of species from wetter forests that produce extremely large seeds and unadorned diaspores. The most widespread species in this study tend to be large plants (particularly robust lianes) and to produce fleshy fruit, but they tend not to have relatively large seeds. The association between large seeds, large plants, fleshy fruit and productive habitats is discussed as part of an evolutionary strategy favouring fitness in populations close to carrying capacity. We review some problems with focusing on establishment chances per seed as the driver towards association between large seeds, large plants and productive rain-forest habitats (the difficult-establishment hypothesis). Instead we suggest that production of large, short-lived seeds by long-lived plants in temporally stable, closed habitats may reflect the limited evolutionary potential for strategies enhancing colonization (e.g. producing large numbers of dormant seeds), thus allowing the establishment benefits of large seeds greater selective influence (the slow-replacement hypothesis). The association of fleshy fruit with large seeds probably reflects the difficulty of dispersing large seeds by other means (the difficult-dispersal hypothesis). JF - Journal of Biogeography AU - Butler, D W AU - Green, R J AU - Lamb, D AU - McDonald, WJF AU - Forster, P I AD - School of Integrative Biology, University of Queensland 4072, Australia, don.butler@epa.qld.gov.au Y1 - 2007/10// PY - 2007 DA - Oct 2007 SP - 1736 EP - 1750 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 34 IS - 10 SN - 0305-0270, 0305-0270 KW - Sustainability Science Abstracts; Ecology Abstracts KW - Australia KW - life-form KW - plant life history KW - Queensland KW - seed dispersal KW - seed size KW - subtropical rain forest KW - Fruits KW - Seed dispersal KW - Seeds KW - Trees KW - Biogeography KW - Dispersal KW - Habitat KW - Evolution KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19463296?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Biogeography&rft.atitle=Biogeography+of+seed-dispersal+syndromes%2C+life-forms+and+seed+sizes+among+woody+rain-forest+plants+in+Australia%27s+subtropics&rft.au=Butler%2C+D+W%3BGreen%2C+R+J%3BLamb%2C+D%3BMcDonald%2C+WJF%3BForster%2C+P+I&rft.aulast=Butler&rft.aufirst=D&rft.date=2007-10-01&rft.volume=34&rft.issue=10&rft.spage=1736&rft.isbn=&rft.btitle=&rft.title=Journal+of+Biogeography&rft.issn=03050270&rft_id=info:doi/10.1111%2Fj.1365-2699.2007.01734.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Seed dispersal; Fruits; Seeds; Biogeography; Trees; Dispersal; Habitat; Evolution DO - http://dx.doi.org/10.1111/j.1365-2699.2007.01734.x ER - TY - JOUR T1 - Gene expression profiling in the lung and liver of PFOA-exposed mouse fetuses. AN - 68206248; 17681415 AB - Perfluorooctanoic acid (PFOA) is a stable perfluoroalkyl acid used to synthesize fluoropolymers during the manufacture of a wide variety of products. Concerns have been raised over the potential health effects of PFOA because it is persistent in the environment and can be detected in blood and other tissues of many animal species, including humans. PFOA has also been shown to induce growth deficits and mortality in murine neonates. To better understand the mechanism of PFOA induced developmental toxicity, lung and liver gene expression profiling was conducted in PFOA-exposed full-term mouse fetuses. Thirty timed-pregnant CD-1 mice were orally dosed from gestation days 1-17 with either 0, 1, 3, 5, or 10mg/(kgday) PFOA in water. At term, fetal lung and liver were collected, total RNA prepared, and samples pooled from three fetuses per litter. Five biological replicates consisting of individual litter samples were then evaluated for each treatment group using Affymetrix mouse 430_2 microarrays. The expression of genes related to fatty acid catabolism was altered in both the fetal liver and lung. In the fetal liver, the effects of PFOA were robust and also included genes associated with lipid transport, ketogenesis, glucose metabolism, lipoprotein metabolism, cholesterol biosynthesis, steroid metabolism, bile acid biosynthesis, phospholipid metabolism, retinol metabolism, proteosome activation, and inflammation. These changes are consistent with transactivation of PPARalpha, although, with regard to bile acid biosynthesis and glucose metabolism, non-PPARalpha related effects were suggested as well. Additional studies will be needed to more thoroughly address the role of PPARalpha, and other nuclear receptors, in PFOA mediated developmental toxicity. JF - Toxicology AU - Rosen, Mitchell B AU - Thibodeaux, Julie R AU - Wood, Carmen R AU - Zehr, Robert D AU - Schmid, Judith E AU - Lau, Christopher AD - Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA. rosen.mitch@epa.gov Y1 - 2007/09/24/ PY - 2007 DA - 2007 Sep 24 SP - 15 EP - 33 VL - 239 IS - 1-2 SN - 0300-483X, 0300-483X KW - Caprylates KW - 0 KW - Environmental Pollutants KW - Fatty Acids KW - Fluorocarbons KW - RNA, Messenger KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Administration, Oral KW - Mice, Inbred Strains KW - Animals KW - RNA, Messenger -- metabolism KW - Oligonucleotide Array Sequence Analysis KW - Dose-Response Relationship, Drug KW - Mice KW - Maternal Exposure KW - Female KW - Pregnancy KW - Fatty Acids -- metabolism KW - Gene Expression Profiling KW - Environmental Pollutants -- toxicity KW - Liver -- drug effects KW - Fetal Development -- physiology KW - Lung -- drug effects KW - Fluorocarbons -- toxicity KW - Lung -- embryology KW - Liver -- metabolism KW - Fetal Development -- drug effects KW - Caprylates -- toxicity KW - Lung -- metabolism KW - Liver -- embryology KW - Gene Expression Regulation, Developmental -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68206248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Gene+expression+profiling+in+the+lung+and+liver+of+PFOA-exposed+mouse+fetuses.&rft.au=Rosen%2C+Mitchell+B%3BThibodeaux%2C+Julie+R%3BWood%2C+Carmen+R%3BZehr%2C+Robert+D%3BSchmid%2C+Judith+E%3BLau%2C+Christopher&rft.aulast=Rosen&rft.aufirst=Mitchell&rft.date=2007-09-24&rft.volume=239&rft.issue=1-2&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-16 N1 - Date created - 2007-08-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Elevated PBDE levels in pet cats: sentinels for humans? AN - 68410815; 17948778 AB - Co-incident with the introduction of polybrominated diphenyl ethers (PBDEs) into household materials nearly 30 years ago, feline hyperthyroidism (FH) has increased dramatically. Risk of developing FH is associated with indoor living and consumption of canned catfood. We hypothesized that increases in FH were, in part, related to increased PBDE exposure, with key routes of exposure being diet and ingestion of house dust. This study was designed to determine whether body burdens of PBDEs in hyperthyroid (HT) cats were greater than that of young or sick non-HT cats. Serum samples and clinical information were collected from 23 cats. Serum and dry and canned cat food were analyzed for PBDEs. A spectrum of BDE congeners was detected in all cats, with BDE-47, 99, 207, and 209 predominating. Mean +/- standard error (and median) cumulative sigma PBDE serum concentrations of young, old non-HT, and HT cats were 4.3 +/- 1.5 (3.5), 10.5 +/- 3.5 (5.9), and 12.7 +/- 3.9 (6.2) ng/mL, respectively. Due to high variability within each group, no association was detected between HT cats and sigma PBDE levels. Indicative of age- or disease-dependent changes in PBDE metabolism, BDE-47/99 ratios were inversely correlated with age, and 47/99 and 100/ 99 ratios in HT cats were significantly lower than those in the other cats. Overall, sigma PBDE levels in cats were 20- to 100-fold greater than median levels in U.S. adults. Our results support the hypothesis that cats are highly exposed to PBDEs; hence, pet cats may serve as sentinels to better assess human exposure and adverse health outcomes related to low-level but chronic PBDE exposure. JF - Environmental science & technology AU - Dye, Janice A AU - Venier, Marta AU - Zhu, Lingyan AU - Ward, Cynthia R AU - Hites, Ronald A AU - Birnbaum, Linda S AD - U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Experimental Toxicology Division, Research Triangle Park, North Carolina 27711, USA. dye.janice@epa.gov Y1 - 2007/09/15/ PY - 2007 DA - 2007 Sep 15 SP - 6350 EP - 6356 VL - 41 IS - 18 SN - 0013-936X, 0013-936X KW - Halogenated Diphenyl Ethers KW - 0 KW - Phenyl Ethers KW - Polybrominated Biphenyls KW - pentabromodiphenyl ether KW - 7REL09ZX35 KW - Index Medicus KW - Animals KW - Drug Residues -- analysis KW - Humans KW - Environmental Exposure -- analysis KW - Cats KW - Animal Feed -- analysis KW - Environmental Exposure -- adverse effects KW - Polybrominated Biphenyls -- blood KW - Cat Diseases -- pathology KW - Cat Diseases -- chemically induced KW - Phenyl Ethers -- toxicity KW - Hyperthyroidism -- pathology KW - Cat Diseases -- blood KW - Polybrominated Biphenyls -- toxicity KW - Phenyl Ethers -- blood KW - Hyperthyroidism -- blood KW - Hyperthyroidism -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68410815?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Elevated+PBDE+levels+in+pet+cats%3A+sentinels+for+humans%3F&rft.au=Dye%2C+Janice+A%3BVenier%2C+Marta%3BZhu%2C+Lingyan%3BWard%2C+Cynthia+R%3BHites%2C+Ronald+A%3BBirnbaum%2C+Linda+S&rft.aulast=Dye&rft.aufirst=Janice&rft.date=2007-09-15&rft.volume=41&rft.issue=18&rft.spage=6350&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-20 N1 - Date created - 2007-10-22 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Environ Sci Technol. 2007 Sep 15;41(18):6319-20 [17948772] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Embayment characteristic time and biology via tidal prism model AN - 20452300; 7547289 AB - Transport time scales are often offered by scientists, and accepted by ecologists, as qualitative indicators of the susceptibility of ecological components within an embayment. However, rigorous quantitative methods were never presented to confirm this intuition. Transport time scales in water bodies are classically based on their physical and chemical aspects rather than their ecological and biological character. The direct connection between a physical time scale and an ecological effect has to be investigated in order to quantitatively relate a transport time scale to ecology. This concept is presented here with some general guidelines and clarifying examples. To be able to relate physical time scales to biological processes, a simple tidal prism model is developed that calculates temporal changes in concentration and the related exposure. This approach provides a quick method to calculate the characteristic time for transport in a large number of embayments, which can also help in classification endeavors. JF - Estuarine, Coastal and Shelf Science AU - Abdelrhman, MA AD - USEPA-AED, abdelrhman.mohamed@epa.gov Y1 - 2007/09/15/ PY - 2007 DA - 2007 Sep 15 SP - 742 EP - 755 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 74 IS - 4 SN - 0272-7714, 0272-7714 KW - Ecology Abstracts; Sustainability Science Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Mathematical models KW - Classification KW - Temporal variations KW - Estuaries KW - Tidal cycles KW - Brackish KW - Tidal models KW - Transport processes KW - Models KW - O 2010:Physical Oceanography KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies KW - Q2 09167:Tides, surges and sea level UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20452300?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Embayment+characteristic+time+and+biology+via+tidal+prism+model&rft.au=Abdelrhman%2C+MA&rft.aulast=Abdelrhman&rft.aufirst=MA&rft.date=2007-09-15&rft.volume=74&rft.issue=4&rft.spage=742&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2007.05.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Mathematical models; Classification; Temporal variations; Tidal cycles; Estuaries; Transport processes; Tidal models; Models; Brackish DO - http://dx.doi.org/10.1016/j.ecss.2007.05.008 ER - TY - CPAPER T1 - 2005 Water Withdrawals in Alabama T2 - 21st Annual Alabama Water Resources Conference AN - 39470348; 4662371 JF - 21st Annual Alabama Water Resources Conference AU - Littlepage, Tom AU - Hutson, Susan AU - Harper, Michael AU - Tinney, Jim Y1 - 2007/09/05/ PY - 2007 DA - 2007 Sep 05 KW - USA, Alabama KW - Droughts KW - Climate KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39470348?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=21st+Annual+Alabama+Water+Resources+Conference&rft.atitle=2005+Water+Withdrawals+in+Alabama&rft.au=Littlepage%2C+Tom%3BHutson%2C+Susan%3BHarper%2C+Michael%3BTinney%2C+Jim&rft.aulast=Littlepage&rft.aufirst=Tom&rft.date=2007-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=21st+Annual+Alabama+Water+Resources+Conference&rft.issn=&rft_id=info:doi/ L2 - http://auei.auburn.edu/conference/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - GIS in Water Resource Management T2 - 21st Annual Alabama Water Resources Conference AN - 39415730; 4662367 JF - 21st Annual Alabama Water Resources Conference AU - Henderson, Phillip AU - Littlepage, Tom Y1 - 2007/09/05/ PY - 2007 DA - 2007 Sep 05 KW - Geographic information systems KW - Water resources KW - Water management KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39415730?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=21st+Annual+Alabama+Water+Resources+Conference&rft.atitle=GIS+in+Water+Resource+Management&rft.au=Henderson%2C+Phillip%3BLittlepage%2C+Tom&rft.aulast=Henderson&rft.aufirst=Phillip&rft.date=2007-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=21st+Annual+Alabama+Water+Resources+Conference&rft.issn=&rft_id=info:doi/ L2 - http://auei.auburn.edu/conference/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Salmon 2100 Project: Options to Protect, Restore, and Enhance Salmon along the West Coast of North America T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39499917; 4660434 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Lackey, Robert Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - North America KW - Salmon KW - Coasts KW - Anadromous species KW - Salmonidae KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39499917?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=The+Salmon+2100+Project%3A+Options+to+Protect%2C+Restore%2C+and+Enhance+Salmon+along+the+West+Coast+of+North+America&rft.au=Lackey%2C+Robert&rft.aulast=Lackey&rft.aufirst=Robert&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Lower Des Plaines River and Chicago Waterway System - Temperature Issues along a Major Urban Waterway T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39499713; 4660394 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Frevert, Toby AU - Twait, Scott Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - USA, Illinois, Chicago KW - Temperature effects KW - Rivers KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39499713?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=Lower+Des+Plaines+River+and+Chicago+Waterway+System+-+Temperature+Issues+along+a+Major+Urban+Waterway&rft.au=Frevert%2C+Toby%3BTwait%2C+Scott&rft.aulast=Frevert&rft.aufirst=Toby&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In-Stream and Watershed Predictors of Genetic Diversity, Effective Population Size and Immigration Across River-Stream Networks T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39478853; 4660292 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Blum, Michael AU - Bagley, Mark AU - Waits, Eric AU - Jackson, Suzanne AU - Daniel, Bernie AU - McCormick, Frank AU - Chaloud, Deborah AU - Lazorchak, James Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - Immigration KW - Watersheds KW - Genetic diversity KW - Population genetics KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39478853?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=In-Stream+and+Watershed+Predictors+of+Genetic+Diversity%2C+Effective+Population+Size+and+Immigration+Across+River-Stream+Networks&rft.au=Blum%2C+Michael%3BBagley%2C+Mark%3BWaits%2C+Eric%3BJackson%2C+Suzanne%3BDaniel%2C+Bernie%3BMcCormick%2C+Frank%3BChaloud%2C+Deborah%3BLazorchak%2C+James&rft.aulast=Blum&rft.aufirst=Michael&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Over-Winter Juvenile Coho Salmon Growth and Survival in a Coastal Oregon Stream Network T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39476610; 4661260 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Wigington, Parker AU - Ebersole, Joseph AU - Colvin, Mike AU - Miller, Bruce AU - Hansen, Bruce AU - Lavigne, Henry AU - Baker, Joan AU - Church, Robbins Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - USA, Oregon KW - Survival KW - Salmon KW - Streams KW - Anadromous species KW - Growth KW - Oncorhynchus kisutch KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39476610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=Over-Winter+Juvenile+Coho+Salmon+Growth+and+Survival+in+a+Coastal+Oregon+Stream+Network&rft.au=Wigington%2C+Parker%3BEbersole%2C+Joseph%3BColvin%2C+Mike%3BMiller%2C+Bruce%3BHansen%2C+Bruce%3BLavigne%2C+Henry%3BBaker%2C+Joan%3BChurch%2C+Robbins&rft.aulast=Wigington&rft.aufirst=Parker&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Stable Isotope Studies on the use of Marine-Derived Nutrients by Coho Salmon Juveniles in an Oregon Coast Range Stream T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39475002; 4661245 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Church, Robbins AU - Ebersole, Joe AU - Wigington, Jim AU - Rensmeyer, Kirk AU - Lavigne, Hank Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - USA, Oregon KW - USA, Coast Range KW - Nutrients KW - Isotopes KW - Salmon KW - Streams KW - Coasts KW - Anadromous species KW - Oncorhynchus kisutch KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39475002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=Stable+Isotope+Studies+on+the+use+of+Marine-Derived+Nutrients+by+Coho+Salmon+Juveniles+in+an+Oregon+Coast+Range+Stream&rft.au=Church%2C+Robbins%3BEbersole%2C+Joe%3BWigington%2C+Jim%3BRensmeyer%2C+Kirk%3BLavigne%2C+Hank&rft.aulast=Church&rft.aufirst=Robbins&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The San Francisco Estuary: Trying to do Ecology in a Constantly Changing Environment T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39464407; 4660458 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Herbold, Bruce AU - Baxter, Randall AU - Breuer, Richard AU - Chotkowski, Michael AU - Culberson, Steven AU - Mueller-Solger, Anke AU - Sommer, Ted AU - Souza, Kelly Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - USA, California, San Francisco Estuary KW - Ecology KW - Estuaries KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39464407?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=The+San+Francisco+Estuary%3A+Trying+to+do+Ecology+in+a+Constantly+Changing+Environment&rft.au=Herbold%2C+Bruce%3BBaxter%2C+Randall%3BBreuer%2C+Richard%3BChotkowski%2C+Michael%3BCulberson%2C+Steven%3BMueller-Solger%2C+Anke%3BSommer%2C+Ted%3BSouza%2C+Kelly&rft.aulast=Herbold&rft.aufirst=Bruce&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assessing the Biological Quality of Streams within the United States T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39433061; 4660315 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Paulsen, Steve Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - USA KW - Streams KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39433061?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=Assessing+the+Biological+Quality+of+Streams+within+the+United+States&rft.au=Paulsen%2C+Steve&rft.aulast=Paulsen&rft.aufirst=Steve&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Variation in Juvenile Coho Salmon End-Of-Summer Size and Abundance: Hierarchical Analysis of Habitat Effects T2 - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AN - 39423503; 4661259 JF - 137th Annual Meeting of the American Fisheries Society (AFS 2007) AU - Ebersole, Joseph AU - Colvin, Mike AU - Wigington, Parker AU - Joan, Baker AU - Church, Robbins AU - Compton, Jana AU - Cairns, Michael AU - LaVigne, Hank Y1 - 2007/09/02/ PY - 2007 DA - 2007 Sep 02 KW - Habitat KW - Abundance KW - Salmon KW - Anadromous species KW - Oncorhynchus kisutch KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39423503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.atitle=Variation+in+Juvenile+Coho+Salmon+End-Of-Summer+Size+and+Abundance%3A+Hierarchical+Analysis+of+Habitat+Effects&rft.au=Ebersole%2C+Joseph%3BColvin%2C+Mike%3BWigington%2C+Parker%3BJoan%2C+Baker%3BChurch%2C+Robbins%3BCompton%2C+Jana%3BCairns%2C+Michael%3BLaVigne%2C+Hank&rft.aulast=Ebersole&rft.aufirst=Joseph&rft.date=2007-09-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=137th+Annual+Meeting+of+the+American+Fisheries+Society+%28AFS+2007%29&rft.issn=&rft_id=info:doi/ L2 - http://web.fisheries.org/sf/images/documents/online_oral_abstracts.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Partitioning, desorption, and dechlorination of a PCB congener in sediment slurry supernatants. AN - 68400496; 17937311 AB - Partitioning and desorption played specific roles in the dechlorination of 2-chlorobiphenyl (2-CIBP) in sediment slurry supernatants, which are suspensions of dissolved organic matter (DOM). In short-term experiments, the partition coefficient (Kp) was related to the apparent dechlorination rate constant. The Kp value (160 L g(DOC)(-1)), which is independent of the DOM concentration, was determined based on the decrease of the apparent rate constant with the increase of the DOM concentration. In the long-term experiments, the overall rate of dechlorination can be described with a two-compartment model. The time constant for the sediment compartment was related to Kp and the desorption rate constant (k(d)). The k(d) value (0.21 h(-1)) was determined based on the decrease of the time constant values with an increasing DOM concentration. The use of DOM suspensions allowed a short time for equilibrium. Separation of the aqueous and DOM phases was not needed due to the dechlorination of 2-CIBP. The fundamental relationships between overall dechlorination rate constant and properties of the contaminant and sediment were established. JF - Environmental science & technology AU - Fang, Yuanxiang AU - Al-Abed, Souhail R AD - National Risk Management Research Laboratory, United States Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, Ohio 45268, USA. Y1 - 2007/09/01/ PY - 2007 DA - 2007 Sep 01 SP - 6253 EP - 6258 VL - 41 IS - 17 SN - 0013-936X, 0013-936X KW - Biphenyl Compounds KW - 0 KW - 2-chlorobiphenyl KW - 2E08SP4D3P KW - Chlorine KW - 4R7X1O2820 KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - Biphenyl Compounds -- chemistry KW - Kinetics KW - Adsorption KW - Geologic Sediments -- chemistry KW - Polychlorinated Biphenyls -- chemistry KW - Water Purification -- methods KW - Chlorine -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68400496?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Partitioning%2C+desorption%2C+and+dechlorination+of+a+PCB+congener+in+sediment+slurry+supernatants.&rft.au=Fang%2C+Yuanxiang%3BAl-Abed%2C+Souhail+R&rft.aulast=Fang&rft.aufirst=Yuanxiang&rft.date=2007-09-01&rft.volume=41&rft.issue=17&rft.spage=6253&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-16 N1 - Date created - 2007-10-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Deciding which chemical mixtures risk assessment methods work best for what mixtures. AN - 68338803; 16997340 AB - The most commonly used chemical mixtures risk assessment methods involve simple notions of additivity and toxicological similarity. Newer methods are emerging in response to the complexities of chemical mixture exposures and effects. Factors based on both science and policy drive decisions regarding whether to conduct a chemical mixtures risk assessment and, if so, which methods to employ. Scientific considerations are based on positive evidence of joint toxic action, elevated human exposure conditions or the potential for significant impacts on human health. Policy issues include legislative drivers that may mandate action even though adequate toxicity data on a specific mixture may not be available and risk assessment goals that impact the choice of risk assessment method to obtain the amount of health protection desired. This paper discusses three important concepts used to choose among available approaches for conducting a chemical mixtures risk assessment: (1) additive joint toxic action of mixture components; (2) toxicological interactions of mixture components; and (3) chemical composition of complex mixtures. It is proposed that scientific support for basic assumptions used in chemical mixtures risk assessment should be developed by expert panels, risk assessment methods experts, and laboratory toxicologists. This is imperative to further develop and refine quantitative methods and provide guidance on their appropriate applications. Risk assessors need scientific support for chemical mixtures risk assessment methods in the form of toxicological data on joint toxic action for high priority mixtures, statistical methods for analyzing dose-response for mixtures, and toxicological and statistical criteria for determining sufficient similarity of complex mixtures. JF - Toxicology and applied pharmacology AU - Teuschler, Linda K AD - U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Cincinnati, OH 45268, USA. teuschler.linda@epa.gov Y1 - 2007/09/01/ PY - 2007 DA - 2007 Sep 01 SP - 139 EP - 147 VL - 223 IS - 2 SN - 0041-008X, 0041-008X KW - Toxins, Biological KW - 0 KW - Index Medicus KW - Animals KW - Humans KW - Algorithms KW - Risk Assessment -- methods KW - Decision Making KW - Food Contamination -- prevention & control KW - Toxins, Biological -- chemistry KW - Food Contamination -- analysis KW - Environmental Exposure -- analysis KW - Toxins, Biological -- poisoning KW - Toxins, Biological -- analysis KW - Environmental Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68338803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Deciding+which+chemical+mixtures+risk+assessment+methods+work+best+for+what+mixtures.&rft.au=Teuschler%2C+Linda+K&rft.aulast=Teuschler&rft.aufirst=Linda&rft.date=2007-09-01&rft.volume=223&rft.issue=2&rft.spage=139&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-30 N1 - Date created - 2007-10-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Experimental and mathematical modeling methods for the investigation of toxicological interactions. AN - 68337581; 16996550 AB - While procedures have been developed and used for many years to assess risk and determine acceptable exposure levels to individual chemicals, most cases of environmental contamination can result in concurrent or sequential exposure to more than one chemical. Toxicological predictions of such combinations must be based on an understanding of the mechanisms of action and interaction of the components of the mixtures. Statistical and experimental methods test the existence of toxicological interactions in a mixture. However, these methods are limited to experimental data ranges for which they are derived, in addition to limitations caused by response differences from experimental animals to humans. Empirical methods such as isobolograms, median-effect principle and response surface methodology (RSM) are based on statistical experimental design and regression of data. For that reason, the predicted response surfaces can be used for extrapolation across dose regions where interaction mechanisms are not anticipated to change. In general, using these methods for predictions can be problematic without including biologically based mechanistic descriptions that can account for dose and species differences. Mechanistically based models, such as physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) models, include explicit descriptions of interaction mechanisms which are related to target tissues levels. These models include dose-dependent mechanistic hypotheses of toxicological interactions which can be tested by model-directed experimental design and used to identify dose regions where interactions are not significant. JF - Toxicology and applied pharmacology AU - El-Masri, Hisham A AD - Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. el-masri.hisham@epa.gov Y1 - 2007/09/01/ PY - 2007 DA - 2007 Sep 01 SP - 148 EP - 154 VL - 223 IS - 2 SN - 0041-008X, 0041-008X KW - Complex Mixtures KW - 0 KW - Hazardous Substances KW - Index Medicus KW - Threshold Limit Values KW - Animals KW - Humans KW - Hazardous Substances -- pharmacokinetics KW - Hazardous Substances -- poisoning KW - Complex Mixtures -- poisoning KW - Complex Mixtures -- pharmacokinetics KW - Drug Interactions KW - Computational Biology -- methods KW - Models, Theoretical UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68337581?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Experimental+and+mathematical+modeling+methods+for+the+investigation+of+toxicological+interactions.&rft.au=El-Masri%2C+Hisham+A&rft.aulast=El-Masri&rft.aufirst=Hisham&rft.date=2007-09-01&rft.volume=223&rft.issue=2&rft.spage=148&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-30 N1 - Date created - 2007-10-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Synthesis of thermally stable carboxymethyl cellulose/metal biodegradable nanocomposites for potential biological applications. AN - 68250793; 17665946 AB - A green approach is described that generates bulk quantities of nanocomposites containing transition metals such as Cu, Ag, In, and Fe at room temperature using a biodegradable polymer, carboxymethyl cellulose (CMC), by reacting respective metal salts with the sodium salt of CMC in aqueous media. These nanocomposites exhibit broader decomposition temperatures when compared with control CMC, and Ag-based CMC nanocomposites exhibit a luminescent property at longer wavelengths. The noble metals such as Au, Pt, and Pd do not react at room temperature with aqueous solutions of CMC, but do so rapidly under microwave irradiation (MW) conditions at 100 degrees C. This environmentally benign approach, which provides facile entry to the production of multiple shaped noble nanostructures without using any toxic reducing agent such as sodium borohydride (NaBH4), hydroxylamine hydrochloride, and so forth, and/or a capping/surfactant agent, and which uses a benign biodegradable polymer CMC, could find widespread technological and medicinal applications. The ensuing nanocomposites derived at room temperature and MW conditions were characterized using scanning electron microscopy, transmission electron microscopy, infrared spectroscopy, UV-visible spectroscopy, X-ray mapping, energy-dispersive analysis, and thermogravimetric analysis. JF - Biomacromolecules AU - Nadagouda, Mallikarjuna N AU - Varma, Rajender S AD - Sustainable Technology Division, U.S. Environmental Protection Agency, National Risk Management Research Laboratory, 26 West Martin Luther King Drive, MS 443, Cincinnati, Ohio 45268, USA. Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 2762 EP - 2767 VL - 8 IS - 9 SN - 1525-7797, 1525-7797 KW - Biocompatible Materials KW - 0 KW - Metals KW - Carboxymethylcellulose Sodium KW - K679OBS311 KW - Index Medicus KW - Biocompatible Materials -- chemistry KW - Fluorescence KW - Temperature KW - Materials Testing KW - Microscopy, Electron, Scanning KW - Nanostructures -- chemistry KW - Carboxymethylcellulose Sodium -- chemistry KW - Metals -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68250793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biomacromolecules&rft.atitle=Synthesis+of+thermally+stable+carboxymethyl+cellulose%2Fmetal+biodegradable+nanocomposites+for+potential+biological+applications.&rft.au=Nadagouda%2C+Mallikarjuna+N%3BVarma%2C+Rajender+S&rft.aulast=Nadagouda&rft.aufirst=Mallikarjuna&rft.date=2007-09-01&rft.volume=8&rft.issue=9&rft.spage=2762&rft.isbn=&rft.btitle=&rft.title=Biomacromolecules&rft.issn=15257797&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-11-28 N1 - Date created - 2007-09-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Impact of smoking and thiocyanate on perchlorate and thyroid hormone associations in the 2001-2002 national health and nutrition examination survey. AN - 68240315; 17805424 AB - Findings from a recent large study suggest that perchlorate at commonly occurring exposure concentrations may decrease thyroid hormone levels in some women. Decreases in thyroid hormone seen with perchlorate exposure could be even greater in people with concomitant exposure to agents such as thiocyanate that may affect the thyroid by mechanisms similar to those of perchlorate. We used data from the National Health and Nutrition Examination Survey to assess the impact of smoking and thiocyanate on the relationship between urinary per-chlorate and serum thyroxine (T(4)) and thyroid-stimulating hormone (TSH). In women with urinary iodine levels or = 100 microg/L or in men. These results suggest that thiocyanate in tobacco smoke and perchlorate interact in affecting thyroid function, and this effect can take place at commonly occurring perchlorate exposures. Agents other than tobacco smoke might cause similar interactions, and further research on these agents could help identify people who are particularly susceptible to perchlorate. JF - Environmental health perspectives AU - Steinmaus, Craig AU - Miller, Mark D AU - Howd, Robert AD - Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, California 94612, USA. csteinmaus@oehha.ca.gov Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 1333 EP - 1338 VL - 115 IS - 9 SN - 0091-6765, 0091-6765 KW - Environmental Pollutants KW - 0 KW - Perchlorates KW - Thiocyanates KW - thiocyanate KW - 302-04-5 KW - Thyrotropin KW - 9002-71-5 KW - Iodine KW - 9679TC07X4 KW - Creatinine KW - AYI8EX34EU KW - Cotinine KW - K5161X06LL KW - Thyroxine KW - Q51BO43MG4 KW - perchlorate KW - VLA4NZX2P4 KW - Index Medicus KW - iodine KW - tobacco smoke KW - thyroid KW - cotinine KW - interactions KW - Cotinine -- urine KW - Creatinine -- urine KW - Thyrotropin -- blood KW - Humans KW - Nutrition Surveys KW - Male KW - Female KW - Thiocyanates -- toxicity KW - Iodine -- urine KW - Environmental Pollutants -- toxicity KW - Perchlorates -- toxicity KW - Smoking -- metabolism KW - Smoking -- adverse effects KW - Thyroxine -- blood KW - Environmental Pollutants -- urine KW - Thiocyanates -- urine KW - Perchlorates -- urine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68240315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Impact+of+smoking+and+thiocyanate+on+perchlorate+and+thyroid+hormone+associations+in+the+2001-2002+national+health+and+nutrition+examination+survey.&rft.au=Steinmaus%2C+Craig%3BMiller%2C+Mark+D%3BHowd%2C+Robert&rft.aulast=Steinmaus&rft.aufirst=Craig&rft.date=2007-09-01&rft.volume=115&rft.issue=9&rft.spage=1333&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-01-15 N1 - Date created - 2007-09-06 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Endocrinology. 1999 Dec;140(12):5705-11 [10579335] J Expo Sci Environ Epidemiol. 2007 Jul;17(4):400-7 [17051137] Eur J Endocrinol. 2002 Feb;146(2):153-61 [11834423] J Occup Environ Med. 2002 May;44(5):393 [12024682] Environ Health Perspect. 2002 Sep;110(9):927-37 [12204829] Thyroid. 2002 Oct;12(10):897-902 [12487772] Clin Endocrinol (Oxf). 2003 Sep;59(3):282-8 [12919150] J Clin Endocrinol Metab. 2004 Jan;89(1):181-7 [14715847] Arch Intern Med. 1984 Mar;144(3):501-3 [6703821] Clin Endocrinol (Oxf). 1985 Mar;22(3):287-92 [3978834] Scand J Clin Lab Invest. 1986 May;46(3):245-51 [3715377] Proc Soc Exp Biol Med. 1988 Apr;187(4):391-7 [3127831] J Intern Med. 1991 May;229(5):407-13 [2040866] Thyroid. 1994 Fall;4(3):327-31 [7833671] N Engl J Med. 1995 Oct 12;333(15):1001-2 [7666896] N Engl J Med. 1995 Oct 12;333(15):964-9 [7666915] J Clin Endocrinol Metab. 1998 Oct;83(10):3401-8 [9768638] Am J Public Health. 1998 Oct;88(10):1503-9 [9772852] J Occup Environ Med. 1999 Apr;41(4):248-60 [10224590] J Occup Environ Med. 1999 May;41(5):409-11 [10337612] N Engl J Med. 1999 Aug 19;341(8):549-55 [10451459] Endocrinology. 1952 May;50(5):537-49 [14936940] Metabolism. 1952 Nov;1(6):533-9 [13002073] J Clin Endocrinol Metab. 2004 Dec;89(12):6077-86 [15579761] Thyroid. 2004 Dec;14(12):1012-9 [15650353] J Clin Endocrinol Metab. 2005 Feb;90(2):700-6 [15572417] Thyroid. 2005 Aug;15(8):917-29 [16131334] J Clin Endocrinol Metab. 2005 Sep;90(9):5489-96 [16148346] Thyroid. 2005 Sep;15(9):963-75 [16187904] Environ Health Perspect. 2005 Nov;113(11):1607-14 [16263519] Pediatrics. 2006 Jan;117(1):161-7 [16396874] Eur J Endocrinol. 2006 Feb;154(2):229-35 [16452535] J Clin Endocrinol Metab. 2006 Jul;91(7):2721-4 [16636123] Annu Rev Nutr. 2006;26:293-322 [16704348] Eur J Endocrinol. 2006 Oct;155(4):495-512 [16990649] Environ Health Perspect. 2006 Dec;114(12):1865-71 [17185277] Thyroid. 2000 Nov;10(11):951-63 [11128722] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate. AN - 68194824; 17576809 AB - The metabolism of (alphaS)-cyano-3-phenoxybenzyl (1R, 3R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate (deltamethrin) and (alphaS)-cyano-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutyrate (esfenvalerate) by rat and human liver microsomes differs with respect to the biotransformation pathway (oxidation versus hydrolysis) responsible for their clearance. This study aims to further explore the species differences in the metabolism of these chemicals. Using a parent depletion approach, rat and human cytochromes P450 (P450s) were screened for their ability to eliminate deltamethrin or esfenvalerate during in vitro incubations. Rat P450 isoforms CYP1A1, CYP2C6, CYP2C11, and CYP3A2 and human P450 isoforms CYP2C8, CYP2C19, and CYP3A5 were capable of metabolizing either pyrethroid. Human CYP2C9 metabolized esfenvalerate but not deltamethrin. Rat and human P450s that metabolize esfenvalerate and deltamethrin do so with similar kinetics. In addition to the liver, a potential site of metabolic elimination of pyrethroids is the blood via serum carboxylesterase (CE) hydrolysis. The serum of rats, but not humans, contains significant quantities of CE. Deltamethrin and esfenvalerate were metabolized effectively by rat serum and a purified rat serum CE. In contrast, neither pyrethroid was metabolized by human serum or purified human serum esterases (acetylcholinesterase and butyrylcholinesterase). These studies suggest that the difference in rates of oxidative metabolism of pyrethroids by rat and human hepatic microsomes is dependent on the expression levels of individual P450 isoforms rather than their specific activity. Furthermore, these studies show that the metabolic elimination of deltamethrin and esfenvalerate in blood may be important to their disposition in rats but not in humans. JF - Drug metabolism and disposition: the biological fate of chemicals AU - Godin, Stephen J AU - Crow, J Allen AU - Scollon, Edward J AU - Hughes, Michael F AU - DeVito, Michael J AU - Ross, Matthew K AD - United States Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Resource Laboratory, Experimental Toxicology Division, Pharmacokinetics Branch, Research Triangle Park, NC 27711, USA. Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 1664 EP - 1671 VL - 35 IS - 9 SN - 0090-9556, 0090-9556 KW - Insecticides KW - 0 KW - Isoenzymes KW - Nitriles KW - Pyrethrins KW - decamethrin KW - 2JTS8R821G KW - Cytochrome P-450 Enzyme System KW - 9035-51-2 KW - Esterases KW - EC 3.1.- KW - fenvalerate KW - Z6MXZ39302 KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Spodoptera KW - Biotransformation KW - Microsomes, Liver -- metabolism KW - Kinetics KW - Humans KW - Species Specificity KW - Hydrolysis KW - Male KW - Isoenzymes -- metabolism KW - Risk Assessment KW - Insecticides -- metabolism KW - Nitriles -- pharmacokinetics KW - Nitriles -- metabolism KW - Insecticides -- pharmacokinetics KW - Esterases -- blood KW - Cytochrome P-450 Enzyme System -- metabolism KW - Pyrethrins -- pharmacokinetics KW - Pyrethrins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68194824?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Drug+metabolism+and+disposition%3A+the+biological+fate+of+chemicals&rft.atitle=Identification+of+rat+and+human+cytochrome+p450+isoforms+and+a+rat+serum+esterase+that+metabolize+the+pyrethroid+insecticides+deltamethrin+and+esfenvalerate.&rft.au=Godin%2C+Stephen+J%3BCrow%2C+J+Allen%3BScollon%2C+Edward+J%3BHughes%2C+Michael+F%3BDeVito%2C+Michael+J%3BRoss%2C+Matthew+K&rft.aulast=Godin&rft.aufirst=Stephen&rft.date=2007-09-01&rft.volume=35&rft.issue=9&rft.spage=1664&rft.isbn=&rft.btitle=&rft.title=Drug+metabolism+and+disposition%3A+the+biological+fate+of+chemicals&rft.issn=00909556&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-12-06 N1 - Date created - 2007-08-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A dosimetric analysis of the acute behavioral effects of inhaled toluene in rats. AN - 68155102; 17548890 AB - Knowledge of the appropriate metric of dose for a toxic chemical facilitates quantitative extrapolation of toxicity observed in the laboratory to the risk of adverse effects in the human population. Here, we utilize a physiologically based toxicokinetic (PBTK) model for toluene, a common volatile organic compound (VOC), to illustrate that its acute behavioral effects in rats can be quantitatively predicted on the basis of its concentration in the brain. Rats previously trained to perform a visual signal detection task for food reward performed the task while inhaling toluene (0, 1200, 1600, 2000, and 2400 ppm in different test sessions). Accuracy and speed of responding were both decreased by toluene; the magnitude of these effects increased with increasing concentration of the vapor and with increasing duration of exposure. Converting the exposure conditions to brain toluene concentration using the PBTK model yielded a family of overlapping curves for each end point, illustrating that the effects of toluene can be described quantitatively by its internal dose at the time of behavioral assessment. No other dose metric, including inhaled toluene concentration, duration of exposure, the area under the curve of either exposure (ppm h), or modeled brain toluene concentration (mg-h/kg), provided unambiguous predictions of effect. Thus, the acute behavioral effects of toluene (and of other VOCs with a similar mode of action) can be predicted for complex exposure scenarios by simulations that estimate the concentration of the VOC in the brain from the exposure scenario. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Bushnell, Philip J AU - Oshiro, Wendy M AU - Samsam, Tracey E AU - Benignus, Vernon A AU - Krantz, Quentin Todd AU - Kenyon, Elaina M AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. bushnell.philip@epa.gov Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 181 EP - 189 VL - 99 IS - 1 SN - 1096-6080, 1096-6080 KW - Solvents KW - 0 KW - Toluene KW - 3FPU23BG52 KW - Index Medicus KW - Reaction Time -- drug effects KW - Animals KW - Rats, Long-Evans KW - Area Under Curve KW - Dose-Response Relationship, Drug KW - Brain -- drug effects KW - Learning -- drug effects KW - Brain -- metabolism KW - Models, Biological KW - Rats KW - Signal Detection, Psychological -- drug effects KW - Attention -- drug effects KW - Administration, Inhalation KW - Male KW - Behavior, Animal -- drug effects KW - Solvents -- toxicity KW - Toluene -- pharmacokinetics KW - Solvents -- pharmacokinetics KW - Toluene -- toxicity KW - Inhalation Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68155102?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=A+dosimetric+analysis+of+the+acute+behavioral+effects+of+inhaled+toluene+in+rats.&rft.au=Bushnell%2C+Philip+J%3BOshiro%2C+Wendy+M%3BSamsam%2C+Tracey+E%3BBenignus%2C+Vernon+A%3BKrantz%2C+Quentin+Todd%3BKenyon%2C+Elaina+M&rft.aulast=Bushnell&rft.aufirst=Philip&rft.date=2007-09-01&rft.volume=99&rft.issue=1&rft.spage=181&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-04 N1 - Date created - 2007-08-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Assessing Progress and Prospects in Coastal Louisiana's Restoration AN - 58759182; 2008-103183 AB - Levee planning, ecosystem restoration, redevelopment, and funding are key components to restoring coastal Louisiana following Hurricane Katrina. Below, the authors analyze recent developments in region and consider ideas and plans for its future. Adapted from the source document. JF - National Wetlands Newsletter AU - Evans, David AU - Ettinger, John AD - Wetlands Division, U.S. Environmental Protection Agency, Washington, D.C. Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 10 EP - 12 PB - Environmental Law Institute, Washington DC VL - 29 IS - 5 SN - 0164-0712, 0164-0712 KW - Environment and environmental policy - Water, waterways, and water management KW - Environment and environmental policy - Weather, climate, and natural disasters KW - Hurricanes KW - Conservation of resources KW - Dams KW - Louisiana KW - Coastal zone management KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58759182?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=National+Wetlands+Newsletter&rft.atitle=Assessing+Progress+and+Prospects+in+Coastal+Louisiana%27s+Restoration&rft.au=Evans%2C+David%3BEttinger%2C+John&rft.aulast=Evans&rft.aufirst=David&rft.date=2007-09-01&rft.volume=29&rft.issue=5&rft.spage=10&rft.isbn=&rft.btitle=&rft.title=National+Wetlands+Newsletter&rft.issn=01640712&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2008-03-05 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Louisiana; Conservation of resources; Coastal zone management; Hurricanes; Dams ER - TY - JOUR T1 - Cost Analysis of Particulate Matter Control Programs -- A Case Study of Tokyo AN - 58758167; 2010-104005 AB - The objectives of this case study were to assess economic costs of existing environmental policies of particulate matter (PM) in Tokyo and compare the costs to ) estimates of benefits developed previously. The purchasing power parity-adjusted one year estimates for the costs of PM pollution control and prevention were: (1) $720 million (USD) for stationary source controls, (2) a range of $690 million to $1.1 billion for diesel motor vehicle controls, (3) $4.2 million for governmental employee salaries, (4) $50 million for governmental financial assistance, and (5) a range of $1.5 billion to $1.9 billion for total costs. Overall these cost results appear more likely to be overestimates than underestimates due to a number of conservative assumptions, in particular for mobile source controls. Using human health and productivity benefits calculated in a previous study to be $38 billion USD, and annualized capital and operating costs from this work, the best net ratio of benefits to costs was 20 to 1. This suggests that Tokyo's PM pollution control policies in total were economically very effective in the past, and that stricter controls or broader regulatory coverage can be justified in the future. Adapted from the source document. JF - Journal of Risk Research AU - Voorhees, A Scott AU - Uchiyama, Iwao AD - Department of Urban and Environmental Engineering, Kyoto University, 5109 Lansdowne Drive, Durham, NC 27712, USA Tel:(919) 541-5509, Fax: (919) 541-5509 voorhees.scott@epa.gov Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 759 EP - 772 PB - Routledge/Taylor & Francis, Abingdon UK VL - 10 IS - 6 SN - 1366-9877, 1366-9877 KW - Economic conditions and policy - Economic theory KW - Environment and environmental policy - Wastes and waste management KW - Manufacturing and heavy industry - Industrial management, production, and productivity KW - Transportation and transportation policy - Roads and land transport KW - Manufacturing and heavy industry - Automotive industry KW - Environment and environmental policy - Pollution and environmental degradation KW - Air pollution, cost, particulate matter, Japan, PM KW - Air pollution KW - Cost KW - Tokyo, Japan KW - Motor vehicles KW - Pollution control in industry KW - Environmental conditions KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58758167?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Risk+Research&rft.atitle=Cost+Analysis+of+Particulate+Matter+Control+Programs+--+A+Case+Study+of+Tokyo&rft.au=Voorhees%2C+A+Scott%3BUchiyama%2C+Iwao&rft.aulast=Voorhees&rft.aufirst=A&rft.date=2007-09-01&rft.volume=10&rft.issue=6&rft.spage=759&rft.isbn=&rft.btitle=&rft.title=Journal+of+Risk+Research&rft.issn=13669877&rft_id=info:doi/10.1080%2F13669870701342561 LA - English DB - PAIS Index N1 - Date revised - 2012-05-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Tokyo, Japan; Environmental conditions; Cost; Air pollution; Pollution control in industry; Motor vehicles DO - http://dx.doi.org/10.1080/13669870701342561 ER - TY - JOUR T1 - A Combined Local and Nonlocal Closure Model for the Atmospheric Boundary Layer. Part II: Application and Evaluation in a Mesoscale Meteorological Model AN - 21054582; 7734652 AB - A new combined local and nonlocal closure atmospheric boundary layer model called the Asymmetric Convective Model, version 2, (ACM2) was described and tested in one-dimensional form and was compared with large-eddy simulations and field data in Part I. Herein, the incorporation of the ACM2 into the fifth-generation Pennsylvania State University-NCAR Mesoscale Model (MM5) is described. Model simulations using the MM5 with the ACM2 are made for the summer of 2004 and evaluated through comparison with surface meteorological measurements, rawinsonde profile measurements, and observed planetary boundary layer (PBL) heights derived from radar wind profilers. Overall model performance is as good as or better than similar MM5 evaluation studies. The MM5 simulations with the ACM2 compare particularly well to PBL heights derived from radar wind profilers during the afternoon hours. The ACM2 is designed to simulate the vertical mixing of any modeled quantity realistically for both meteorological models and air quality models. The next step, to be described in a subsequent article, is to incorporate the ACM2 into the Community Multiscale Air Quality (CMAQ) model for testing and evaluation. JF - Journal of Applied Meteorology and Climatology AU - Pleim, JE AD - Atmospheric Sciences Modeling Division, Air Resources Laboratory, NOAA, Research Triangle Park, NC 27711-0000., pleimjon@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 1396 EP - 1409 PB - American Meteorological Society, 45 Beacon St. Boston MA 02108-3693 USA VL - 46 IS - 9 SN - 1558-8424, 1558-8424 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution KW - Meteorological models KW - Climate KW - Simulation KW - Rawinsondes KW - Air quality KW - Large eddy simulations KW - Air quality models KW - Meteorological measurements KW - profilers KW - Numerical simulations KW - Boundary layers KW - Radar KW - Convective activity KW - summer KW - Meteorology KW - Mesoscale models KW - Climatology KW - Mesoscale model MM5 KW - Radar wind profiler KW - Atmospheric boundary layer KW - M2 551.510.52:Troposphere (551.510.52) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21054582?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology+and+Climatology&rft.atitle=A+Combined+Local+and+Nonlocal+Closure+Model+for+the+Atmospheric+Boundary+Layer.+Part+II%3A+Application+and+Evaluation+in+a+Mesoscale+Meteorological+Model&rft.au=Pleim%2C+JE&rft.aulast=Pleim&rft.aufirst=JE&rft.date=2007-09-01&rft.volume=46&rft.issue=9&rft.spage=1396&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology+and+Climatology&rft.issn=15588424&rft_id=info:doi/10.1175%2FJAM2534.1 L2 - http://ams.allenpress.com/perlserv/?request=get-abstract&doi=10.1175%2FJAM2534.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution; Meteorological models; Rawinsondes; Air quality; Large eddy simulations; Air quality models; Meteorological measurements; Numerical simulations; Convective activity; Mesoscale model MM5; Climatology; Mesoscale models; Atmospheric boundary layer; Radar wind profiler; profilers; Boundary layers; Climate; Radar; summer; Simulation; Meteorology DO - http://dx.doi.org/10.1175/JAM2534.1 ER - TY - JOUR T1 - Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals AN - 21054060; 7539840 AB - An in vitro steroidogenesis assay using H295R human adenocarcinoma cells has been suggested as a possible alternative to gonad explant assays for use as a Tier I screening assay to detect endocrine active chemicals capable of modulating steroid hormone synthesis. This study is one of the first to investigate the utility of the H295R assay for predicting effects and/or understanding mechanisms of action across species and tissues. Six chemicals, including one selective aromatase inhibitor (fadrozole), four fungicides (fenarimol, ketoconazole, prochloraz, and vinclozolin), and one herbicide (prometon), were tested in both the H295R steroidogenesis assay, and an in vitro steroidogenesis assay using fathead minnow ovary explants. All six chemicals caused significant alterations in 17 beta -estradiol (E2) and/or testosterone (T) production in vitro. Effects of ketoconazole, prochloraz, and prometon were similar in both assays. However, there were differences in the profile of responses for T for fadrozole and fenarimol, and for T and E2 for vinclozolin. In terms of sensitivity, steroid production in the H295R assay was most sensitive for detecting the effects of fadrozole, fenarimol, and prochloraz, but was less sensitive than the fathead minnow ovary explant assay to the effects of ketoconazole and vinclozolin. The H295R assay was consistently less variable (among replicates) than the fathead minnow ovary explant assay. However, the ovary explant assay was more predictive of in vivo effects of the six chemicals on fathead minnows than the H295R system. Further characterization of autoregulatory capacities, interaction of steroid-hormone receptor pathways with steroidogenesis, and metabolic capabilities of each system are needed for either system to provide clear and informative insights regarding a chemical's mechanism of action. Overall, however, results of this study suggest that both the H295R and fathead minnow ovary explant assays have utility for identifying endocrine-active chemicals in screening-type applications. JF - Ecotoxicology and Environmental Safety AU - Villeneuve, D L AU - Ankley, G T AU - Makynen, E A AU - Blake, L S AU - Greene, K J AU - Higley, E B AU - Newsted, J L AU - Giesy, J P AU - Hecker, M AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, 6201 Congdon Blvd., Duluth, MN, 55804, USA., villeneuve.dan@epa.gov Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 20 EP - 32 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 68 IS - 1 SN - 0147-6513, 0147-6513 KW - Toxicology Abstracts; Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Freshwater KW - Freshwater fish KW - Steroidogenesis KW - Utilities KW - Sex hormones KW - Aromatase KW - Ecotoxicology KW - Assay KW - Synthesis KW - Testing Procedures KW - Vinclozolin KW - Triazine Pesticides KW - Fathead Minnows KW - Ketoconazole KW - Testosterone KW - Bioassays KW - Profiles KW - Ovaries KW - Toxicity testing KW - Explants KW - Chemicals KW - Pollution effects KW - steroids KW - Prochloraz KW - gonads KW - 17 beta -Estradiol KW - Steroids KW - Herbicides KW - Toxicity KW - Steroid hormones KW - Fungicides KW - steroid hormones KW - Gonads KW - Adenocarcinoma KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - AQ 00008:Effects of Pollution KW - X 24330:Agrochemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21054060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ecotoxicology+and+Environmental+Safety&rft.atitle=Comparison+of+fathead+minnow+ovary+explant+and+H295R+cell-based+steroidogenesis+assays+for+identifying+endocrine-active+chemicals&rft.au=Villeneuve%2C+D+L%3BAnkley%2C+G+T%3BMakynen%2C+E+A%3BBlake%2C+L+S%3BGreene%2C+K+J%3BHigley%2C+E+B%3BNewsted%2C+J+L%3BGiesy%2C+J+P%3BHecker%2C+M&rft.aulast=Villeneuve&rft.aufirst=D&rft.date=2007-09-01&rft.volume=68&rft.issue=1&rft.spage=20&rft.isbn=&rft.btitle=&rft.title=Ecotoxicology+and+Environmental+Safety&rft.issn=01476513&rft_id=info:doi/10.1016%2Fj.ecoenv.2007.03.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Ecotoxicology; Fungicides; Pollution effects; Herbicides; Freshwater fish; Steroids; Sex hormones; Vinclozolin; Steroid hormones; Ketoconazole; Steroidogenesis; Testosterone; Prochloraz; Aromatase; 17 beta -Estradiol; Gonads; Ovaries; Adenocarcinoma; Explants; Chemicals; Bioassays; gonads; steroid hormones; steroids; Toxicity testing; Testing Procedures; Profiles; Triazine Pesticides; Assay; Fathead Minnows; Toxicity; Synthesis; Utilities; Freshwater DO - http://dx.doi.org/10.1016/j.ecoenv.2007.03.001 ER - TY - JOUR T1 - A Combined Local and Nonlocal Closure Model for the Atmospheric Boundary Layer. Part I: Model Description and Testing AN - 21052457; 7734651 AB - The modeling of the atmospheric boundary layer during convective conditions has long been a major source of uncertainty in the numerical modeling of meteorological conditions and air quality. Much of the difficulty stems from the large range of turbulent scales that are effective in the convective boundary layer (CBL). Both small-scale turbulence that is subgrid in most mesoscale grid models and large-scale turbulence extending to the depth of the CBL are important for the vertical transport of atmospheric properties and chemical species. Eddy diffusion schemes assume that all of the turbulence is subgrid and therefore cannot realistically simulate convective conditions. Simple nonlocal closure PBL models, such as the Blackadar convective model that has been a mainstay PBL option in the fifth-generation Pennsylvania State University-National Center for Atmospheric Research Mesoscale Model (MM5) for many years and the original asymmetric convective model (ACM), also an option in MM5, represent large-scale transport driven by convective plumes but neglect small-scale, subgrid turbulent mixing. A new version of the ACM (ACM2) has been developed that includes the nonlocal scheme of the original ACM combined with an eddy diffusion scheme. Thus, the ACM2 is able to represent both the supergrid- and subgrid-scale components of turbulent transport in the convective boundary layer. Testing the ACM2 in one-dimensional form and comparing it with large-eddy simulations and field data from the 1999 Cooperative Atmosphere-Surface Exchange Study demonstrates that the new scheme accurately simulates PBL heights, profiles of fluxes and mean quantities, and surface-level values. The ACM2 performs equally well for both meteorological parameters (e.g., potential temperature, moisture variables, and winds) and trace chemical concentrations, which is an advantage over eddy diffusion models that include a nonlocal term in the form of a gradient adjustment. JF - Journal of Applied Meteorology and Climatology AU - Pleim, JE AD - Atmospheric Sciences Modeling Division, Air Resources Laboratory, NOAA, Research Triangle Park, NC 27711, pleimjon@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 1383 EP - 1395 PB - American Meteorological Society, 45 Beacon St. Boston MA 02108-3693 USA VL - 46 IS - 9 SN - 1558-8424, 1558-8424 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Atmospheric pollution models KW - Air quality KW - Small-scale turbulence KW - Numerical models KW - Meteorological parameters KW - Chemical speciation KW - Atmospheric chemistry models KW - Diffusion KW - Meteorology KW - Climatology KW - Mesoscale model MM5 KW - Atmospheric boundary layer KW - Turbulence KW - cooperatives KW - Plumes KW - Large-scale turbulence KW - Meteorological conditions KW - Mathematical models KW - Atmospheric pollution KW - Climate KW - Temperature KW - Simulation KW - Convective boundary layer KW - Turbulent mixing KW - Large eddy simulations KW - Potential temperature KW - Boundary layers KW - Convective activity KW - Mesoscale models KW - Atmosphere-surface exchange KW - Atmospheric research KW - Eddy diffusion KW - M2 551.510.52:Troposphere (551.510.52) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21052457?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology+and+Climatology&rft.atitle=A+Combined+Local+and+Nonlocal+Closure+Model+for+the+Atmospheric+Boundary+Layer.+Part+I%3A+Model+Description+and+Testing&rft.au=Pleim%2C+JE&rft.aulast=Pleim&rft.aufirst=JE&rft.date=2007-09-01&rft.volume=46&rft.issue=9&rft.spage=1383&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology+and+Climatology&rft.issn=15588424&rft_id=info:doi/10.1175%2FJAM2539.1 L2 - http://ams.allenpress.com/perlserv/?request=get-abstract&doi=10.1175%2FJAM2539.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution; Atmospheric pollution models; Convective boundary layer; Turbulent mixing; Air quality; Large eddy simulations; Small-scale turbulence; Numerical models; Meteorological parameters; Potential temperature; Convective activity; Atmospheric chemistry models; Mesoscale models; Mesoscale model MM5; Climatology; Atmospheric boundary layer; Atmosphere-surface exchange; Meteorological conditions; Large-scale turbulence; Eddy diffusion; Atmospheric research; Mathematical models; Chemical speciation; Boundary layers; Climate; Temperature; Simulation; Meteorology; Diffusion; Plumes; cooperatives; Turbulence DO - http://dx.doi.org/10.1175/JAM2539.1 ER - TY - JOUR T1 - Competitive Binding Comparison of Endocrine-Disrupting Compounds to Recombinant Androgen Receptor from Fathead Minnow, Rainbow Trout, and Human AN - 20869411; 8173820 AB - Typically, in vitro hazard assessments for the identification of endocrine-disrupting compounds (EDCs), including those outlined in the Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) Tier 1 Screening protocols, utilize mammalian receptors. Evidence, however, exists that fish sex steroid hormone receptors differ from mammalian receptors both structurally and in their binding affinities for some steroids and environmental chemicals. Most of the binding studies to date have been conducted using cytosolic preparations from various tissues. In the present study, we compare competitive binding of a set of compounds to full-length recombinant rainbow trout androgen receptor alpha (rtAR), fathead minnow androgen receptor (fhAR), and human androgen receptor (hAR), each expressed in COS cells. Saturation binding and subsequent Scatchard analysis using [ super(3)H]R1881, a high-affinity synthetic androgen, revealed an equilibrium dissociation constant (K sub(d)) of 0.11 nM for the rtAR, 1.8 nM for the fhAR, and 0.84 nM for the hAR. Compounds, including endogenous and synthetic steroids, known mammalian antiandrogens, and environmental compounds, were tested for competitive binding to each of the three receptors. Overall, agreement existed across receptors as to binding versus nonbinding for all compounds tested in this study. Minor differences, however, were found in the relative order of binding of the compounds to the individual receptors. Studies such as these will facilitate the identification of EDCs that may differentially affect specific species and aid in the development and support of future risk assessment protocols. JF - Environmental Toxicology and Chemistry AU - Wilson, Vickie S AU - Cardon, Mary C AU - Gray, Earl L AU - Hartig, Phillip C AD - U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Reproductive Toxicology Division, Research Triangle Park, North Carolina 27711 Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 1793 EP - 1802 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 26 IS - 9 SN - 0730-7268, 0730-7268 KW - Fathead minnow KW - Rainbow trout KW - Pollution Abstracts; Toxicology Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Androgen receptor KW - Human KW - Endocrine disruptors KW - Chemicals KW - Risk assessment KW - endocrine disruptors KW - Anadromous species KW - advisory committees KW - Pollution effects KW - steroids KW - Steroid hormone receptors KW - Freshwater fish KW - Toxicity tests KW - Sex hormones KW - Steroids KW - Receptors KW - Oncorhynchus mykiss KW - Steroid hormones KW - Androgen receptors KW - Pimephales promelas KW - antiandrogens KW - Scatchard analysis KW - Endocrinology KW - steroid hormones KW - Androgens KW - Q5 08504:Effects on organisms KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20869411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=Competitive+Binding+Comparison+of+Endocrine-Disrupting+Compounds+to+Recombinant+Androgen+Receptor+from+Fathead+Minnow%2C+Rainbow+Trout%2C+and+Human&rft.au=Wilson%2C+Vickie+S%3BCardon%2C+Mary+C%3BGray%2C+Earl+L%3BHartig%2C+Phillip+C&rft.aulast=Wilson&rft.aufirst=Vickie&rft.date=2007-09-01&rft.volume=26&rft.issue=9&rft.spage=1793&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F06-593R.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Endocrinology; Anadromous species; Receptors; Pollution effects; Freshwater fish; Toxicity tests; Steroids; Sex hormones; Risk assessment; Androgen receptors; antiandrogens; Scatchard analysis; Endocrine disruptors; Steroid hormone receptors; Steroid hormones; Androgens; Chemicals; endocrine disruptors; advisory committees; steroid hormones; steroids; Pimephales promelas; Oncorhynchus mykiss DO - http://dx.doi.org/10.1897/06-593R.1 ER - TY - JOUR T1 - Opportunistic Aspergillus pathogens measured in home and hospital tap water by quantitative PCR (QPCR) AN - 20844875; 7626349 AB - Opportunistic fungal pathogens are a concern because of the increasing number of immunocompromised patients. The goal of this research was to test a simple extraction method and rapid quantitative PCR (QPCR) measurement of the occurrence of potential pathogens, Aspergillus fumigatus, A. flavus, A. terreus and A. niger, in home tap water and a hospital water supply. Water samples were taken from the kitchen tap in the homes of 60 patients who were diagnosed with legionellosis. Water samples were also taken from three locations in a hospital that generated all of its hot water by flash heating. Opportunistic infectious agents Aspergillus fumigatus, A. flavus, A. terreus and A. niger were measured using QPCR. Aspergillus terreus DNA was found in 16.7% and A fumigatus DNA in 1.7% of the samples taken from the kitchen tap. None of the Aspergillus species were found in any of the hospital water samples. The development of a simple DNA extraction method along with QPCR analysis is suitable for rapid screening of tap water for opportunistic fungal pathogens. This simple method can be used to obtain pathogen occurrence results in about 3 h, instead of waiting days to weeks for culture data. Obtaining pathogen occurrence data in a timely manner could promote the elimination of the pathogens from the water supply of immunocompromised patients. JF - Journal of Water and Health AU - Vesper, S J AU - Rogers, ME AU - Neely, AN AU - Haugland, R A AD - National Exposure Research Laboratory, US Environmental Protection Agency, 26 West M. L. King Drive, Cincinnati, OH 45216, USA, vesper.stephen@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 427 EP - 431 VL - 5 IS - 3 SN - 1477-8920, 1477-8920 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Health & Safety Science Abstracts; Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Aspergillus flavus KW - Water sampling KW - Water Analysis KW - Water Sampling KW - Water Supply KW - Water quality KW - Water supplies KW - Drinking Water KW - Polymerase chain reaction KW - Aspergillus terreus KW - Testing Procedures KW - Data processing KW - Pathogens KW - Kitchens KW - Heating KW - Aspergillus fumigatus KW - Immunocompromised hosts KW - Cultures KW - DNA KW - Drinking water KW - Hospitals KW - SW 0810:General KW - P 2000:FRESHWATER POLLUTION KW - K 03400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20844875?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+and+Health&rft.atitle=Opportunistic+Aspergillus+pathogens+measured+in+home+and+hospital+tap+water+by+quantitative+PCR+%28QPCR%29&rft.au=Vesper%2C+S+J%3BRogers%2C+ME%3BNeely%2C+AN%3BHaugland%2C+R+A&rft.aulast=Vesper&rft.aufirst=S&rft.date=2007-09-01&rft.volume=5&rft.issue=3&rft.spage=427&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+and+Health&rft.issn=14778920&rft_id=info:doi/10.2166%2Fwh.2007.038 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Data processing; Immunocompromised hosts; Polymerase chain reaction; Pathogens; Water supplies; Kitchens; Hospitals; Water sampling; DNA; Drinking water; Water quality; Testing Procedures; Drinking Water; Heating; Water Analysis; Water Sampling; Cultures; Water Supply; Aspergillus flavus; Aspergillus fumigatus; Aspergillus terreus DO - http://dx.doi.org/10.2166/wh.2007.038 ER - TY - JOUR T1 - Transparency Tube Monitoring as an Indicator of Fish Community Health AN - 20760533; 8015203 AB - Transparency tubes have been shown to be useful tools for suspended solids estimation in flowing waters. Suspended solids and turbidity can impact streams in a number of ways from habitat smothering to visual impairments. Comparison of transparency tube data to the Index of Biotic Integrity (EBI) as measured by the Ohio Environmental Protection Agency shows a strong correlation. Additional data must be gathered to determine whether this is a true relationship. JF - Ohio Journal of Science AU - Zawiski, B AD - Ohio EPA, NE District Office, 2110 Aurora Road, Twinsburg, OH 44087, USA Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 82 EP - 83 VL - 107 IS - 4 SN - 0030-0950, 0030-0950 KW - Ecology Abstracts; ASFA 1: Biological Sciences & Living Resources; Water Resources Abstracts KW - Transparency KW - Environmental Protection KW - Suspended particulate matter KW - Tubes KW - Habitat KW - Streams KW - Environmental protection KW - Aquatic Habitats KW - Suspended Solids KW - Fish Populations KW - USA, Ohio KW - Monitoring KW - Turbidity KW - Q1 08341:General KW - SW 0835:Streamflow and runoff KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20760533?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ohio+Journal+of+Science&rft.atitle=Transparency+Tube+Monitoring+as+an+Indicator+of+Fish+Community+Health&rft.au=Zawiski%2C+B&rft.aulast=Zawiski&rft.aufirst=B&rft.date=2007-09-01&rft.volume=107&rft.issue=4&rft.spage=82&rft.isbn=&rft.btitle=&rft.title=Ohio+Journal+of+Science&rft.issn=00300950&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Transparency; Suspended particulate matter; Environmental protection; Turbidity; Habitat; Streams; Aquatic Habitats; Suspended Solids; Environmental Protection; Fish Populations; Monitoring; Tubes; USA, Ohio ER - TY - JOUR T1 - Foreword: Monitoring Wetlands At The Watershed Scale AN - 20714720; 8195906 JF - Wetlands AU - Kentula, ME AD - USEPA, National Health and Environmental Effects Research, Laboratory-Western Ecology Division (NHEERL-WED), 200 S.W. 35th Street, Corvallis, Oregon, USA 97333, kentula.mary@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 412 EP - 415 PB - Society of Wetland Scientists, P.O. Box 1897 Lawrence KS 66044 USA, [mailto:sws@allenpres.com], [URL:http://www.sws.org] VL - 27 IS - 3 SN - 0277-5212, 0277-5212 KW - Ecology Abstracts; Water Resources Abstracts KW - Wetlands KW - Monitoring KW - Watersheds KW - SW 0810:General KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20714720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Wetlands&rft.atitle=Foreword%3A+Monitoring+Wetlands+At+The+Watershed+Scale&rft.au=Kentula%2C+ME&rft.aulast=Kentula&rft.aufirst=ME&rft.date=2007-09-01&rft.volume=27&rft.issue=3&rft.spage=412&rft.isbn=&rft.btitle=&rft.title=Wetlands&rft.issn=02775212&rft_id=info:doi/10.1672%2F0277-5212%282007%29272.0.CO%3B2 L2 - http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0277-5212&volume=27&issue=3&page=412 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-06-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Wetlands; Watersheds; Monitoring DO - http://dx.doi.org/10.1672/0277-5212(2007)27[412:FMWATW]2.0.CO;2 ER - TY - JOUR T1 - Determinants of Variability in Acute to Chronic Toxicity Ratios for Aquatic Invertebrates and Fish AN - 20684059; 8173848 AB - Variability in acute to chronic ratios (ACRs; median lethal or effect concentration divided by chronic value) has been of continuing interest in aquatic toxicology because of the reliance on ACRs to estimate chronic toxicity for chemicals and species with known acute toxicity data but with limited or no information for chronic toxicity. To investigate the variability and significant differences in ACRs, an extensive data set was compiled of 456 same-species pairs of acute and maximum acceptable toxicant concentrations for metals, narcotics, pesticides, and other organic chemicals. The overall median value for 456 aquatic invertebrate and fish ACRs analyzed in the present study was 8.3, with a 16,000-fold range in values (1.1-18,550) and a 32-fold range in 10th and 90th percentile values (2.5-79.5). Median ACRs for taxa, ambient habitat media, chronic test end point, and chemical mode of action (MOA)/class categories generally were similar but, in some cases, extremely variable (ranges of 1 to >10,000). No significant differences (p le 0.05) were found in median ACRs between taxa, although invertebrate ACRs generally were more variable than fish ACRs. Freshwater organisms had median ACRs significantly greater than those of saltwater species and also were more variable. No significant differences were found in median ACRs among chemical MOA/class data sets; however, ACR variance differed significantly among MOAs. Although few significant differences occurred among median ACRs for different groups, those categories that were highly variable are at an increased risk of underestimated chronic toxicity when mean or median ACRs are used. JF - Environmental Toxicology and Chemistry AU - Raimondo, Sandy AU - Montague, Brian J AU - Barron, Mace G AD - U.S. Environmental Protection Agency, National Health and Environmental Effects Laboratory, Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, Florida 32561 Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 2019 EP - 2023 PB - Allen Press, Inc., 810 East Tenth St. PO Box 1897 Lawrence KS 66044 USA, [mailto:webmaster@allenpress.com] VL - 26 IS - 9 SN - 0730-7268, 0730-7268 KW - Pollution Abstracts; Entomology Abstracts; Toxicology Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Acute/chronic ratios KW - Aquatic organisms KW - Mode of action KW - Aquatic toxicity KW - acute toxicity KW - Toxicants KW - Heavy metals KW - Freshwater KW - Freshwater fish KW - Toxicity tests KW - invertebrates KW - Agricultural Chemicals KW - Invertebrata KW - Toxicology KW - Metals KW - Narcotics KW - Habitat KW - Acute Toxicity KW - Water Pollution Effects KW - Fish KW - Chemicals KW - Variability KW - Invertebrates KW - taxa KW - Acute toxicity KW - Chronic toxicity KW - Mode of Action KW - Geochemistry KW - Toxicity KW - Bioaccumulation KW - Pesticides KW - Freshwater organisms KW - Z 05340:Ecology and Behavior KW - P 2000:FRESHWATER POLLUTION KW - Q1 08422:Environmental effects KW - Q5 08504:Effects on organisms KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20684059?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=Determinants+of+Variability+in+Acute+to+Chronic+Toxicity+Ratios+for+Aquatic+Invertebrates+and+Fish&rft.au=Raimondo%2C+Sandy%3BMontague%2C+Brian+J%3BBarron%2C+Mace+G&rft.aulast=Raimondo&rft.aufirst=Sandy&rft.date=2007-09-01&rft.volume=26&rft.issue=9&rft.spage=2019&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F07-069R.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Bioaccumulation; Heavy metals; Pesticides; Geochemistry; Freshwater organisms; Toxicity; Freshwater fish; Toxicity tests; Toxicology; Metals; Toxicants; Chronic toxicity; Narcotics; Acute toxicity; Habitat; Chemicals; Aquatic organisms; acute toxicity; taxa; invertebrates; Mode of Action; Variability; Agricultural Chemicals; Acute Toxicity; Water Pollution Effects; Fish; Invertebrates; Invertebrata; Freshwater DO - http://dx.doi.org/10.1897/07-069R.1 ER - TY - JOUR T1 - Sand Flux Simulations at a Small Scale over a Heterogeneous Mesquite Area of the Northern Chihuahuan Desert AN - 20649017; 9395076 AB - Within areas of the Chihuahuan Desert dominated by honey mesquite bushes (Prosopis glandulosa), soil erosion causes open eroded patches and the formation of large coppice dunes. The airflow patterns around the dunes and through the open areas are correlated with sand flux and erosion. This study uses wind velocity simulations from the Quick Urban and Industrial Complex (QUIC) model in combination with a sand flux parameterization to simulate sand fluxes for each of eight storms occurring in the springs of 2003 and 2004. Total sand fluxes based on the sum of all the sand collectors located within the study domain were usually within 50% of the measured values for each of the storms, with simulations for individual sand collectors also often within 50% of the measured values. Simulated fluxes based on two different sand flux parameterizations were generally within 10% of each other, differing substantially only when the sand flux was low (near the threshold velocity). Good agreement between the field observations with a Sensit instrument and QUIC simulations for the same location and time series suggests that QUIC could be used to predict the spatial and temporal variation of sand flux patterns for a domain. JF - Journal of Applied Meteorology AU - Bowker, George E AU - Gillette, Dale A AU - Bergametti, Gilles AU - Marticorena, Beatrice AU - Heist, David K AD - Atmospheric Modeling Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 1410 EP - 1422 PB - American Meteorological Society, 45 Beacon St. VL - 46 IS - 9 SN - 0894-8763, 0894-8763 KW - Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts KW - Velocity KW - Soil erosion KW - Mesquite KW - Time series analysis KW - Storms KW - Wind velocities KW - Erosion KW - Airflow patterns KW - Numerical simulations KW - Sand KW - Deserts KW - Mexico, Chihuahuan Desert KW - Dunes KW - Fluctuations KW - SW 2060:Effects on water of human nonwater activities KW - M2 551.55:Wind (551.55) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20649017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=Sand+Flux+Simulations+at+a+Small+Scale+over+a+Heterogeneous+Mesquite+Area+of+the+Northern+Chihuahuan+Desert&rft.au=Bowker%2C+George+E%3BGillette%2C+Dale+A%3BBergametti%2C+Gilles%3BMarticorena%2C+Beatrice%3BHeist%2C+David+K&rft.aulast=Bowker&rft.aufirst=George&rft.date=2007-09-01&rft.volume=46&rft.issue=9&rft.spage=1410&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2FJAM2537.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Airflow patterns; Erosion; Numerical simulations; Soil erosion; Time series analysis; Storms; Wind velocities; Deserts; Sand; Dunes; Velocity; Mesquite; Fluctuations; Mexico, Chihuahuan Desert DO - http://dx.doi.org/10.1175/JAM2537.1 ER - TY - JOUR T1 - Using CMAQ for Exposure Modeling and Characterizing the Subgrid Variability for Exposure Estimates AN - 20648108; 9395077 AB - Atmospheric processes and the associated transport and dispersion of atmospheric pollutants are known to be highly variable in time and space. Current air-quality models that characterize atmospheric chemistry effects, for example, the Community Multiscale Air Quality model (CMAQ), provide volume-averaged concentration values for each grid cell in the modeling domain given the stated conditions. Given the assumptions made and the limited set of processes included in any model's implementation, there are many sources of 'unresolved' subgrid variability. This raises the question of the importance of the unresolved subgrid variations on exposure assessment results if such models were to be used to assess air toxics exposure. In this study, the Hazardous Air Pollutant Exposure Model (HAPEM) is applied to estimate benzene and formaldehyde inhalation exposure using ambient annually averaged concentrations predicted by CMAQ to investigate how within-grid variability can affect exposure estimates. An urban plume dispersion model was used to estimate the subgrid variability of annually averaged benzene concentration values within CMAQ grid cells for a modeling domain centered on Philadelphia, Pennsylvania. Significant (greater than a factor of 2) increases in maximum exposure impacts were seen in the exposure estimates in comparison with exposure estimates generated using CMAQ grid-averaged concentration values. These results consider only one source of subgrid variability, namely, the discrete location and distribution of emissions, but they do suggest the importance and value of developing improved characterizations of subgrid concentration variability for use in air toxics exposure assessments. JF - Journal of Applied Meteorology AU - Isakov, Vlad AU - Irwin, John S AU - Ching, Jason Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 1354 EP - 1371 PB - American Meteorological Society, 45 Beacon St. VL - 46 IS - 9 SN - 0894-8763, 0894-8763 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts KW - Inhalation KW - Variability KW - Benzenes KW - Atmospheric pollution models KW - Pollution dispersion KW - Atmospheric processes KW - Formaldehyde KW - Air quality KW - Benzene KW - Pollutants KW - Assessments KW - Exposure KW - Atmospheric chemistry models KW - Emissions KW - Atmospheric pollution dispersion KW - Meteorology KW - Plumes KW - Plume dispersion KW - Atmospheric pollution KW - USA, Pennsylvania, Philadelphia KW - Toxicity KW - Model Studies KW - Air quality models KW - Air pollution KW - Atmospheric dispersion KW - Water Pollution Effects KW - USA, Pennsylvania KW - Atmospheric chemistry KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - SW 3030:Effects of pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20648108?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Meteorology&rft.atitle=Using+CMAQ+for+Exposure+Modeling+and+Characterizing+the+Subgrid+Variability+for+Exposure+Estimates&rft.au=Isakov%2C+Vlad%3BIrwin%2C+John+S%3BChing%2C+Jason&rft.aulast=Isakov&rft.aufirst=Vlad&rft.date=2007-09-01&rft.volume=46&rft.issue=9&rft.spage=1354&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Meteorology&rft.issn=08948763&rft_id=info:doi/10.1175%2FJAM2538.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Atmospheric dispersion; Atmospheric pollution; Atmospheric pollution models; Atmospheric chemistry; Atmospheric chemistry models; Atmospheric processes; Atmospheric pollution dispersion; Plume dispersion; Air quality models; Air pollution; Inhalation; Pollution dispersion; Emissions; Formaldehyde; Meteorology; Air quality; Plumes; Benzene; Benzenes; Variability; Assessments; Pollutants; Water Pollution Effects; Exposure; Toxicity; Model Studies; USA, Pennsylvania, Philadelphia; USA, Pennsylvania DO - http://dx.doi.org/10.1175/JAM2538.1 ER - TY - JOUR T1 - Application of monolithic integrated circuit in hydraulic control reed valve of pumping station AN - 20614970; 7828138 AB - To prevent the phenomena of water hammer in high-lift pumping water station, one kind of intelligent butterfly valve control system of pump station is designed with 8031CPU, PID controller, high accuracy intelligent sensor and other peripheral equipment This design not only rotate speed of electromotor and pipeline pressure can be homeostasis, but also prevents the phenomena of water hammer and makes equipment safety. For the solution of water hammer reliability of equipment is enhanced during the testing time. At the same time, manual debugging is simple and can be used in every lift pumping water station and is compatible to control system of pumping station. It is to be improved at the further time, such as more expensive and high reliability and anti-electromagnetic-jamming of parts. JF - Ningxia Engineering Technology AU - Xu, J AD - Ningxia Guhai Administrative Office of water-lifting, Zhongning 755100, China Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 245 EP - 247 VL - 6 IS - 3 SN - 1671-7244, 1671-7244 KW - Aqualine Abstracts; Water Resources Abstracts KW - Hydraulics KW - Water Hammer KW - Sensors KW - Safety KW - Valves KW - Pumps KW - Pumping KW - Pipelines KW - Control Systems KW - AQ 00001:Water Resources and Supplies KW - SW 6030:Hydraulic machinery UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20614970?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ningxia+Engineering+Technology&rft.atitle=Application+of+monolithic+integrated+circuit+in+hydraulic+control+reed+valve+of+pumping+station&rft.au=Xu%2C+J&rft.aulast=Xu&rft.aufirst=J&rft.date=2007-09-01&rft.volume=6&rft.issue=3&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=Ningxia+Engineering+Technology&rft.issn=16717244&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-01-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Hydraulics; Sensors; Water Hammer; Safety; Pumps; Pipelines; Pumping; Valves; Control Systems ER - TY - JOUR T1 - Estimation of the total daily oral intake of NDMA attributable to drinking water AN - 20552248; 7626341 AB - Disinfection with chlorine and chloramine leads to the formation of many disinfection by-products including N-Nitrosodimethylamine (NDMA). Because NDMA is a probable human carcinogen, public health officials are concerned with its occurrence in drinking water. The goal of this study was to estimate NDMA concentrations from exogenous (i.e., drinking water and food) and endogenous (i.e., formed in the human body) sources, calculate average daily doses for ingestion route exposures and estimate the proportional oral intake (POI) of NDMA attributable to the consumption of drinking water relative to other ingestion sources of NDMA. The POI is predicted to be 0.02% relative to exogenous and endogenous NDMA sources combined. When only exogenous sources are considered, the POI was predicted to be 2.7%. The exclusion of endogenously formed NDMA causes the POI to increase dramatically, reflecting its importance as a potentially major source of exposure and uncertainty in the model. Although concentrations of NDMA in foods are small and human exposure to NDMA from foods is quite low, the contribution from food is predicted to be high relative to that of drinking water. The mean concentration of NDMA in drinking water would need to increase from 2.1 x 10 super(-3) mu g/L to 0.10 mu g/L, a 47-fold increase, for the POI to reach 1%, relative to all sources of NDMA considered in our model, suggesting that drinking water consumption is most likely a minor source of NDMA exposure. JF - Journal of Water and Health AU - Fristachi, A AU - Rice, G AD - Oak Ridge Institute for science and Education assigned to U.S. Environmental Protection Agency, Office of Research and Development National Center for Environmental Assessment, 26 W, Martin Luther King Dr. (MS-A110), Cincinnati, OH 45268, USA, afristac@jhsph.edu Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 341 EP - 355 VL - 5 IS - 3 SN - 1477-8920, 1477-8920 KW - Water Resources Abstracts; Aqualine Abstracts KW - Disinfection KW - Byproducts KW - Model Studies KW - Foods KW - Drinking Water KW - Public Health KW - Exposure KW - Chlorination KW - SW 3030:Effects of pollution KW - SW 3060:Water treatment and distribution KW - AQ 00008:Effects of Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20552248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+and+Health&rft.atitle=Estimation+of+the+total+daily+oral+intake+of+NDMA+attributable+to+drinking+water&rft.au=Fristachi%2C+A%3BRice%2C+G&rft.aulast=Fristachi&rft.aufirst=A&rft.date=2007-09-01&rft.volume=5&rft.issue=3&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+and+Health&rft.issn=14778920&rft_id=info:doi/10.2166%2Fwh.2007.030 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Disinfection; Foods; Public Health; Drinking Water; Exposure; Byproducts; Chlorination; Model Studies DO - http://dx.doi.org/10.2166/wh.2007.030 ER - TY - JOUR T1 - Chemical characterization of volatile organic compounds near the World Trade Center: Ambient concentrations and source apportionment AN - 20550715; 7542844 AB - Concentrations of 53 volatile organic compounds (VOCs) are reported from four locations near the World Trade Center (WTC) (New York, USA) complex for canister samples collected from September 2001 through January 2002. Across the four sampling sites, mean concentrations ranged from 94.5 to 219 mu gm super(-) super(3) for total VOCs. The highest mean concentrations for individual VOCs at any site were for ethane (18.7 mu gm super(-) super(3)), isopentane (17.1 mu gm super(-) super(3)), and m,p-xylenes (17.0 mu gm super(-) super(3)). VOC concentrations were generally highest for samples collected north and west of the WTC complex. Concentrations of total VOCs (and most individual VOCs) decreased from the period when fires were present at the WTC complex (before 19 December 2001) to the period after fires. The EPA Unmix Version 5.0 receptor model was used to assess the impact of WTC fires and recovery efforts on ambient VOC concentrations. Four factors were identified: burning of building debris, a mixed recovery/heating source, motor vehicle exhaust, and a mixed gasoline source. JF - Atmospheric Environment AU - Olson, DA AU - Norris, G A AU - Seila, R L AU - Landis AU - Vette, A F AD - United States Environmental Protection Agency, Research Triangle Park, NC 27711, USA, olson.david@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 5673 EP - 5683 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 27 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - EPA KW - Fires KW - Gasoline KW - Motor vehicles KW - Volatile organic compounds in atmosphere KW - Volatile organic compound emission by motor vehicles KW - ethane KW - burning KW - Volatile organic compounds KW - USA, New York KW - P 9000:ENVIRONMENTAL ACTION KW - M2 551.510.42:Air Pollution (551.510.42) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20550715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Chemical+characterization+of+volatile+organic+compounds+near+the+World+Trade+Center%3A+Ambient+concentrations+and+source+apportionment&rft.au=Olson%2C+DA%3BNorris%2C+G+A%3BSeila%2C+R+L%3BLandis%3BVette%2C+A+F&rft.aulast=Olson&rft.aufirst=DA&rft.date=2007-09-01&rft.volume=41&rft.issue=27&rft.spage=5673&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.02.047 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Fires; Volatile organic compound emission by motor vehicles; Volatile organic compounds in atmosphere; EPA; Gasoline; Motor vehicles; ethane; burning; Volatile organic compounds; USA, New York DO - http://dx.doi.org/10.1016/j.atmosenv.2007.02.047 ER - TY - JOUR T1 - The Measurement of Ambient Bioaerosol Exposure AN - 20518239; 7690988 AB - Monitoring of ambient bioaerosol concentrations through the characterization of outdoor particulate matter (PM) has only been performed on a limited basis in North Carolina (NC) and was the goal of this research. Ambient samples of PM2.5 (fine) and PM10-2.5 (coarse) were collected for a six-month period and analyzed for mold, endotoxins and protein. PM2.5 and PM10-2.5 concentrations of these bioaerosols were reported as a function of PM mass, as well as volume of air sampled. The mass of PM2.5 was almost twice that of the PM10-2.5; however, the protein and endotoxin masses were greater in the coarse than the fine PM indicating an enrichment in the coarse PM. The protein and mold results demonstrated a seasonal pattern, both being higher in the summer than in the winter. Except for an occasional excursion, the endotoxin data remained fairly constant throughout the six months of the study. JF - Aerosol Science & Technology AU - Menetrez, M Y AU - Foarde, K K AU - Esch, R K AU - Dean, T R AU - Betancourt, D A AU - Moore, S A AU - Svendsen, E R AU - Yeatts, K AD - Air Pollution Prevention and Control Division, U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, North Carolina, USA Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 884 EP - 893 PB - Taylor & Francis, 325 Chestnut Street Suite 800 Philadelphia PA 19106 USA, [URL:http://www.taylorandfrancis.com/] VL - 41 IS - 9 SN - 0278-6826, 0278-6826 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Endotoxins KW - Particle size KW - USA, North Carolina KW - Aerosols KW - Bioaerosols KW - Atmospheric pollution KW - Airborne microorganisms KW - Particulates KW - Particulate matter in atmosphere KW - Sulfur dioxide KW - winter KW - Air sampling KW - Proteins KW - summer KW - Seasonal variations KW - P 0000:AIR POLLUTION KW - M2 551.510.3/.4:Physical Properties/Composition (551.510.3/.4) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20518239?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerosol+Science+%26+Technology&rft.atitle=The+Measurement+of+Ambient+Bioaerosol+Exposure&rft.au=Menetrez%2C+M+Y%3BFoarde%2C+K+K%3BEsch%2C+R+K%3BDean%2C+T+R%3BBetancourt%2C+D+A%3BMoore%2C+S+A%3BSvendsen%2C+E+R%3BYeatts%2C+K&rft.aulast=Menetrez&rft.aufirst=M&rft.date=2007-09-01&rft.volume=41&rft.issue=9&rft.spage=884&rft.isbn=&rft.btitle=&rft.title=Aerosol+Science+%26+Technology&rft.issn=02786826&rft_id=info:doi/10.1080%2F02786820701523083 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Particulate matter in atmosphere; Atmospheric pollution; Bioaerosols; Particle size; Endotoxins; Aerosols; winter; Sulfur dioxide; Air sampling; Airborne microorganisms; summer; Proteins; Particulates; Seasonal variations; USA, North Carolina DO - http://dx.doi.org/10.1080/02786820701523083 ER - TY - JOUR T1 - Area of influence (AOI) sensitivity analysis: Application to Atlanta, Georgia AN - 20409468; 7542839 AB - Area of influence (AOI) analysis was applied to determine the geographical extent of the air pollutant precursors contributing to various pollutant levels in the Atlanta metropolitan area. Receptor-oriented sensitivities of ozone and particulate matter (PM) species to emissions of NO sub(x), SO sub(2), NH sub(3), anthropogenic VOC, and elemental carbon were calculated for various combinations of precursor emissions during 1-10 August, 1999. The episode had high observed concentrations of ozone and PM across several days. AOIs differed significantly by day for each sensitivity as well as spatially between pollutants. Ozone sensitivities peaked at 1.0ppb per 1.0moles super(-) super(1) (or per 4.0tonday super(-) super(1)) per 12x12km super(2) model grid of emissions of NO sub(x), but averaged around 0.1ppb over much of Atlanta. Sulfate was the major component of PM, with an average sensitivity of 0.03 mu gm super(-) super(3) per 1.0mols super(-) super(1) (or per 5.5tond super(-) super(1)) per 12x12km super(2) model grid of SO sub(2) emissions and an average of 0.02 mu gm super(-) super(3) per 1.0mols super(-) super(1) per 12x12km super(2) of NO sub(x) emissions. Ammonia had a significant impact on PM through the formation of ammonium sulfate and ammonium nitrate. Elemental carbon had a geographically small area of influence with high values around the receptor. JF - Atmospheric Environment AU - Napelenok, S L AU - Habermacher, F D AU - Akhtar, F AU - Hu, Y AU - Russell, A G AD - Georgia Institute of Technology, Atlanta, Georgia 30332, USA, Napelenok.Sergey@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 5605 EP - 5617 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 27 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Sulfates KW - Ammonium KW - Atmospheric pollution models KW - Atmospheric pollution KW - Ammonia KW - Ammonia content of atmosphere KW - Particulates KW - Air pollution KW - Sulfur dioxide KW - Sensitivity analysis KW - Particulate matter emissions KW - sensitivity analysis KW - Ammonia emissions KW - Volatile organic compound emissions KW - Emissions KW - USA, Georgia, Atlanta KW - metropolitan areas KW - Volatile organic compounds KW - Ozone KW - ammonium nitrate KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20409468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Area+of+influence+%28AOI%29+sensitivity+analysis%3A+Application+to+Atlanta%2C+Georgia&rft.au=Napelenok%2C+S+L%3BHabermacher%2C+F+D%3BAkhtar%2C+F%3BHu%2C+Y%3BRussell%2C+A+G&rft.aulast=Napelenok&rft.aufirst=S&rft.date=2007-09-01&rft.volume=41&rft.issue=27&rft.spage=5605&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.03.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution; Atmospheric pollution models; Sensitivity analysis; Particulate matter emissions; Volatile organic compound emissions; Ammonia emissions; Ammonia content of atmosphere; Air pollution; Sulfates; Ammonium; Sulfur dioxide; Ammonia; sensitivity analysis; Emissions; Particulates; metropolitan areas; Volatile organic compounds; ammonium nitrate; Ozone; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1016/j.atmosenv.2007.03.006 ER - TY - JOUR T1 - Fine particulate source apportionment using data from the USEPA speciation trends network in Chicago, Illinois: Comparison of two source apportionment models AN - 20399182; 7553178 AB - Data from two of the United States Environmental Protection Agency's speciation trends network fine particulate matter sites within Chicago, Illinois were analyzed using the chemical mass balance (CMB) and positive matrix factorization (PMF) models to determine source contributions to the ambient fine particulate concentrations. The results from the two models were compared to determine the similarities and differences in the source contributions. This included examining the differences in the magnitude of the individual source contributions as well as the correlation between the contribution values from the two methods. The results showed that both models predicted sulfates, nitrates and motor vehicles as the three highest fine particle contributors for the two sites accounting for approximately 80% of the total. The PMF model attributed a slightly greater amount of fine particulate to the road salt, steel and soil sources while vegetative burning contributed more in the CMB results. Correlations between the contribution results from the two models were high for sulfates, nitrates and road salt with very good correlations existing for motor vehicles and petroleum refineries. The predicted PMF profiles agreed well with measured source profiles for the major species associated with each source. JF - Atmospheric Environment AU - Rizzo, MJ AU - Scheff, P A AD - Office of Air Quality Planning and Standards, Air Quality Analysis Division, Air Quality Analysis Group, Research Triangle Park, NC 27711, USA, rizzo.michael@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 6276 EP - 6288 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 29 SN - 1352-2310, 1352-2310 KW - Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - USA, Illinois, Chicago KW - Sulfates KW - Atmospheric pollution models KW - Nitrates KW - USA, Illinois KW - Motor vehicles KW - Correlations KW - Particulates KW - Refineries KW - burning KW - Atmospheric pollution by motor vehicles KW - Environmental protection KW - Particulate matter from motor vehicles KW - Soil KW - Salts KW - EPA KW - Petroleum KW - Atmospheric chemistry models KW - Steel KW - Urban areas KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20399182?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Fine+particulate+source+apportionment+using+data+from+the+USEPA+speciation+trends+network+in+Chicago%2C+Illinois%3A+Comparison+of+two+source+apportionment+models&rft.au=Rizzo%2C+MJ%3BScheff%2C+P+A&rft.aulast=Rizzo&rft.aufirst=MJ&rft.date=2007-09-01&rft.volume=41&rft.issue=29&rft.spage=6276&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.03.055 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Atmospheric pollution models; Atmospheric chemistry models; Correlations; Atmospheric pollution by motor vehicles; Environmental protection; Particulate matter from motor vehicles; Soil; Sulfates; EPA; Salts; Nitrates; Petroleum; Motor vehicles; Steel; Refineries; Particulates; burning; Urban areas; USA, Illinois, Chicago; USA, Illinois DO - http://dx.doi.org/10.1016/j.atmosenv.2007.03.055 ER - TY - JOUR T1 - A robust new method for analyzing community change and an example using 83 years of avian response to forest succession AN - 20363464; 7552279 AB - The composition of animal communities changes over time in response to natural processes (disease dynamics, plant community succession) and anthropogenic disturbances (habitat fragmentation, climate change). Detection and analysis of community change is important for regional and site-specific management and for conservation planning. However, formal time series of animal community composition are rare. We describe a distribution-free method for compiling time series from separate studies to test for changes in community composition. The method, based on rank-permutation, is robust to many problems associated with data from separate studies, including unequal sampling effort, variable-length intervals between sampling, and different sampling protocols. We apply the technique to a time series constructed from five surveys of land bird community composition spanning 83 years of forest succession in northern lower Michigan, USA. We found increases in neotropical migrants, area-sensitive birds, and woodland birds. Despite high species turnover, the overall taxonomic composition of the land bird community did not show significant changes. Although more powerful tests can be applied when data are collected under consistent protocols, our approach is a useful alternative when such data are lacking. In the example provided, our method produced coherent results that are consistent with other published studies from the region. JF - Biological Conservation AU - Etterson, MA AU - Etterson, J R AU - Cuthbert, F J AD - Conservation Biology Program, 1985 Upper Buford Circle, St. Paul, MN 55108-6097, United States, etterson.matthew@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 381 EP - 389 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 138 IS - 3-4 SN - 0006-3207, 0006-3207 KW - Sustainability Science Abstracts; Ecology Abstracts KW - Community composition KW - Climatic changes KW - Plant communities KW - Conservation KW - Forests KW - Sampling KW - Succession KW - Habitat fragmentation KW - M3 1010:Issues in Sustainable Development KW - D 04060:Management and Conservation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20363464?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biological+Conservation&rft.atitle=A+robust+new+method+for+analyzing+community+change+and+an+example+using+83+years+of+avian+response+to+forest+succession&rft.au=Etterson%2C+MA%3BEtterson%2C+J+R%3BCuthbert%2C+F+J&rft.aulast=Etterson&rft.aufirst=MA&rft.date=2007-09-01&rft.volume=138&rft.issue=3-4&rft.spage=381&rft.isbn=&rft.btitle=&rft.title=Biological+Conservation&rft.issn=00063207&rft_id=info:doi/10.1016%2Fj.biocon.2007.05.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Community composition; Climatic changes; Plant communities; Forests; Conservation; Sampling; Succession; Habitat fragmentation DO - http://dx.doi.org/10.1016/j.biocon.2007.05.003 ER - TY - JOUR T1 - Perturbation of retinoic acid (RA)-mediated limb development suggests a role for diminished RA signaling in the teratogenesis of ethanol AN - 20353096; 7596885 AB - BACKGROUND: A proposed mechanism for ethanol teratogenicity entails ethanol-mediated reductions in retinoic acid (RA). This premise was investigated utilizing a mouse model, with limb reduction defects as the teratogenic end point. METHODS: Ethanol, Disulfiram, or BMS-189453 was administered to C57BL/6J mice on the 9th day of pregnancy. Forelimb morphology was assessed on gestation day 18 using Alcian blue and Alizarin red staining. Nile blue sulfate or LysoTracker Red (LTR) vital staining identified cell death in the limb bud. The ability of RA to prevent ethanol-induced cell death was assessed by coadministration followed by laser scanning confocal microscopic examination of LTR-staining. In situ hybridization and qPCR were used to examine gene expression in treated limb buds. RESULTS: Ethanol, Disulfiram, and BMS-189453 resulted in postaxial ectrodactyly, intermediate ectrodactyly, and other digital defects. Excessive Nile blue sulfate staining was evident in the presumptive AER following each of the three exposures. Ethanol-induced LTR staining was prevented by RA supplementation. Both in situ hybridization and qPCR illustrated decreases in Shh and Tbx5 in ethanol-exposed embryos as compared to control. CONCLUSIONS: Contrary to studies of prolonged RA deficiency, acute exposure to functional antagonists of RA results in limb defects that are morphologically similar to those caused by ethanol. The rescue of ethanol-induced cell death by RA and similar changes in Shh transcription further suggest that RA contributes to ethanol-induced limb dysmorphology. Moreover, the repression of key mediators of limb development soon after ethanol exposure adds to the existing knowledge of the pathogenic effects of ethanol. Birth Defects Research (Part A), 2007. JF - Birth Defects Research Part A: Clinical and Molecular Teratology AU - Johnson, Corey S AU - Zucker, Robert M AU - Hunter III, Edward Sidney AU - Sulik, Kathleen K AD - The Department of Cell and Developmental Biology, and Bowles Center for Alcohol Studies, The University of North Carolina, Chapel Hill, North Carolina, Hunter.Sid@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 631 EP - 641 PB - John Wiley & Sons, Baffins Lane Chichester W. Sussex PO19 1UD UK, [mailto:customer@wiley.co.uk], [URL:http://www.wiley.com/] VL - 79 IS - 9 SN - 1542-0752, 1542-0752 KW - Toxicology Abstracts KW - Disulfiram KW - Retinoic acid KW - Animal models KW - Transcription KW - Limb buds KW - Teratogenesis KW - Supplementation KW - Antagonists KW - Sulfate KW - Pregnancy KW - Gene expression KW - Hedgehog protein KW - Cell death KW - Limbs KW - Gestation KW - Ectrodactyly KW - Congenital defects KW - Teratogenicity KW - Embryos KW - Ethanol KW - Signal transduction KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20353096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.atitle=Perturbation+of+retinoic+acid+%28RA%29-mediated+limb+development+suggests+a+role+for+diminished+RA+signaling+in+the+teratogenesis+of+ethanol&rft.au=Johnson%2C+Corey+S%3BZucker%2C+Robert+M%3BHunter+III%2C+Edward+Sidney%3BSulik%2C+Kathleen+K&rft.aulast=Johnson&rft.aufirst=Corey&rft.date=2007-09-01&rft.volume=79&rft.issue=9&rft.spage=631&rft.isbn=&rft.btitle=&rft.title=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.issn=15420752&rft_id=info:doi/10.1002%2Fbdra.20387 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Disulfiram; Retinoic acid; Animal models; Transcription; Limb buds; Teratogenesis; Antagonists; Supplementation; Pregnancy; Sulfate; Gene expression; Cell death; Hedgehog protein; Limbs; Ectrodactyly; Gestation; Congenital defects; Embryos; Teratogenicity; Signal transduction; Ethanol DO - http://dx.doi.org/10.1002/bdra.20387 ER - TY - JOUR T1 - Parameter sets for upper and lower bounds on soil-to-indoor-air contaminant attenuation predicted by the Johnson and Ettinger vapor intrusion model AN - 20351204; 7542855 AB - Migration of volatile chemicals from the subsurface into overlying buildings is known as vapor intrusion (VI). Under certain circumstances, people living in homes above contaminated soil or ground water may be exposed to harmful levels of these vapors. A popular VI screening-level algorithm widely used in the United States, Canada and the UK to assess this potential risk is the ''Johnson and Ettinger'' (J&E) model. Concern exists over using the J&E model for deciding whether or not further action is necessary at sites, as many parameters are not routinely measured (or are un-measurable). Using EPA-recommended ranges of parameter values for nine soil-type/source depth combinations, input parameter sets were identified that correspond to bounding results of the J&E model. The results established the existence of generic upper and lower bound parameter sets for maximum and minimum exposure for all soil types and depths investigated. Using the generic upper and lower bound parameter sets, an analysis can be performed that, given the limitations of the input ranges and the model, bounds the attenuation factor in a VI investigation. JF - Atmospheric Environment AU - Tillman, F D AU - Weaver, J W AD - Office of Research and Development, National Exposure Research Laboratory, Ecosystems Research Division, Athens, GA 30605-2700, USA, Weaver.Jim@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 5797 EP - 5806 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 41 IS - 27 SN - 1352-2310, 1352-2310 KW - Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - British Isles KW - Chemicals KW - USA KW - Vapors KW - Canada KW - Algorithms KW - Groundwater pollution KW - Soil contamination KW - Contaminants KW - Groundwater KW - Buildings KW - P 5000:LAND POLLUTION KW - M2 556.38:Groundwater Basins (556.38) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20351204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Atmospheric+Environment&rft.atitle=Parameter+sets+for+upper+and+lower+bounds+on+soil-to-indoor-air+contaminant+attenuation+predicted+by+the+Johnson+and+Ettinger+vapor+intrusion+model&rft.au=Tillman%2C+F+D%3BWeaver%2C+J+W&rft.aulast=Tillman&rft.aufirst=F&rft.date=2007-09-01&rft.volume=41&rft.issue=27&rft.spage=5797&rft.isbn=&rft.btitle=&rft.title=Atmospheric+Environment&rft.issn=13522310&rft_id=info:doi/10.1016%2Fj.atmosenv.2007.05.033 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Algorithms; Groundwater pollution; Chemicals; Vapors; Soil contamination; Groundwater; Contaminants; Buildings; British Isles; USA; Canada DO - http://dx.doi.org/10.1016/j.atmosenv.2007.05.033 ER - TY - JOUR T1 - Amplified fragment length polymorphism analysis of Mycobacterium avium complex isolates recovered from southern California AN - 20336310; 7623919 AB - Fine-scale genotyping methods are necessary in order to identify possible sources of human exposure to opportunistic pathogens belonging to the Mycobacterium avium complex (MAC). In this study, amplified fragment length polymorphism (AFLP) analysis was evaluated for fingerprinting 159 patient and environmental MAC isolates from southern California. AFLP analysis accurately identified strains belonging to M. avium and Mycobacterium intracellulare and differentiated between strains within each species. The method was also able to differentiate strains that were presumed to be genetically identical in two previous studies using large RFLP analysis with PFGE, or PCR-amplification of DNA segments located between insertion sequences IS 1245 and IS1311. For M. avium, drinking-water isolates clustered more closely with each other than with patient or food isolates. Patient isolates were more genetically diverse. None of the environmental isolates shared identical AFLP patterns with patient isolates for either species. There were, however, environmental isolates that shared identical patterns, and patient isolates that shared identical patterns. A subset of the isolates, which are referred to as MX isolates due to their ambiguous identification with the Gen-Probe system, produced AFLP patterns similar to those obtained from M. intracellulare isolates. Sequence analysis of 16S rDNA obtained from the MX isolates suggests that they are strains of M. intracellulare that were not correctly identified by the M. intracellulare AccuProbe from Gen-Probe. JF - Journal of Medical Microbiology AU - Pfaller, S L AU - Aronson, T W AU - Holtzman, A E AU - Covert, T C AD - National Exposure Research Laboratory, US Environmental Protection Agency, Cincinnati, OH, USA, pfaller.stacy@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 1152 EP - 1160 VL - 56 IS - 9 SN - 0022-2615, 0022-2615 KW - Microbiology Abstracts B: Bacteriology KW - Amplified fragment length polymorphism KW - Fingerprinting KW - Mycobacterium avium KW - Genotyping KW - Nucleotide sequence KW - Food KW - DNA KW - Pathogens KW - Mycobacterium intracellulare KW - Insertion sequences KW - rRNA 16S KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20336310?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Microbiology&rft.atitle=Amplified+fragment+length+polymorphism+analysis+of+Mycobacterium+avium+complex+isolates+recovered+from+southern+California&rft.au=Pfaller%2C+S+L%3BAronson%2C+T+W%3BHoltzman%2C+A+E%3BCovert%2C+T+C&rft.aulast=Pfaller&rft.aufirst=S&rft.date=2007-09-01&rft.volume=56&rft.issue=9&rft.spage=1152&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Microbiology&rft.issn=00222615&rft_id=info:doi/10.1099%2Fjmm.0.47075-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-10-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Fingerprinting; Amplified fragment length polymorphism; Food; Nucleotide sequence; Genotyping; DNA; Pathogens; Insertion sequences; rRNA 16S; Mycobacterium avium; Mycobacterium intracellulare DO - http://dx.doi.org/10.1099/jmm.0.47075-0 ER - TY - JOUR T1 - Short-term in vivo exposure to the water contaminant triclosan: Evidence for disruption of thyroxine AN - 20197892; 8177679 AB - Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is a chlorinated phenolic antibacterial compound found as an active ingredient in many personal care and household products. The structural similarity of triclosan to thyroid hormones and recent studies demonstrating activation of the human pregnane X receptor (PXR) and inhibition of diiodothyronine (T sub(2)) sulfotransferases, have raised concerns about adverse effects on thyroid homeostasis. The current research tested the hypothesis that triclosan alters circulating concentrations of thyroxine. The hypothesis was tested using a 4-day oral triclosan exposure (0-1000mg/kg/day) in weanling female Long-Evans rats, followed by measurement of circulating levels of serum total thyroxine (T sub(4)). Dose-dependent decreases in total T sub(4) were observed. The benchmark dose (BMD) and lower bound on the BMD (BMDL) for the effects on T sub(4) were 69.7 and 35.6mg/kg/day, respectively. These data demonstrate that triclosan disrupts thyroid hormone homeostasis in rats. JF - Environmental Toxicology and Pharmacology AU - Crofton, K M AU - Paul, K B AU - DeVito, MJ AU - Hedge, J M AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. EPA, Research Triangle Park, NC, United States, crofton.kevin@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 194 EP - 197 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 24 IS - 2 SN - 1382-6689, 1382-6689 KW - Microbiology Abstracts B: Bacteriology; Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts; Toxicology Abstracts KW - Sulfotransferase KW - Homeostasis KW - Hormones KW - Rats KW - Thyroid hormones KW - Bone mineral density KW - Pollutants KW - Household products KW - Exposure KW - Thyroxine KW - phenolic compounds KW - Testing Procedures KW - Data processing KW - Thyroid KW - Toxicity KW - Inhibition KW - benchmarks KW - Water Pollution Effects KW - pregnane X receptors KW - Contaminants KW - Triclosan KW - Side effects KW - X 24340:Cosmetics, Toiletries & Household Products KW - AQ 00008:Effects of Pollution KW - SW 3030:Effects of pollution KW - P 6000:TOXICOLOGY AND HEALTH KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20197892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Pharmacology&rft.atitle=Short-term+in+vivo+exposure+to+the+water+contaminant+triclosan%3A+Evidence+for+disruption+of+thyroxine&rft.au=Crofton%2C+K+M%3BPaul%2C+K+B%3BDeVito%2C+MJ%3BHedge%2C+J+M&rft.aulast=Crofton&rft.aufirst=K&rft.date=2007-09-01&rft.volume=24&rft.issue=2&rft.spage=194&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Pharmacology&rft.issn=13826689&rft_id=info:doi/10.1016%2Fj.etap.2007.04.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-05-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Thyroid hormones; Data processing; Sulfotransferase; Bone mineral density; Household products; Thyroxine; phenolic compounds; pregnane X receptors; Homeostasis; Contaminants; Triclosan; Side effects; Rats; benchmarks; Thyroid; Hormones; Testing Procedures; Pollutants; Water Pollution Effects; Exposure; Toxicity; Inhibition DO - http://dx.doi.org/10.1016/j.etap.2007.04.008 ER - TY - JOUR T1 - Cumulative Effects of Dibutyl Phthalate and Diethylhexyl Phthalate on Male Rat Reproductive Tract Development: Altered Fetal Steroid Hormones and Genes AN - 19882986; 7561120 AB - Exposure to plasticizers di(n-butyl) phthalate (DBP) and diethylhexyl phthalate (DEHP) during sexual differentiation causes male reproductive tract malformations in rats and rabbits. In the fetal male rat, these two phthalate esters decrease testosterone (T) production and insulin-like peptide 3 (insl3) gene expression, a hormone critical for gubernacular ligament development. We hypothesized that coadministered DBP and DEHP would act in a cumulative dose-additive fashion to induce reproductive malformations, inhibit fetal steroid hormone production, and suppress the expression of insl3 and genes responsible for steroid production. Pregnant Sprague Dawley rats were gavaged on gestation days (GD) 14-18 with vehicle control, 500 mg/kg DBP, 500 mg/kg DEHP, or a combination of DBP and DEHP (500 mg/kg each chemical; DBP + DEHP); the dose of each individual phthalate was one-half of the effective dose predicted to cause a 50% incidence of epididymal agenesis. In experiment one, adult male offspring were necropsied, and reproductive malformations and androgen-dependent organ weights were recorded. In experiment two, GD18 testes were incubated for T production and processed for gene expression by quantitative real-time PCR . The DBP + DEHP dose increased the incidence of many reproductive malformations by greater than or equal to 50%, including epididymal agenesis, and reduced androgen-dependent organ weights in cumulative, dose-additive manner. Fetal T and expression of insl3 and cyp11a were cumulatively decreased by the DBP + DEHP dose. These data indicate that individual phthalates with a similar mechanism of action, but with different active metabolites (monobutyl phthalate versus monoethylhexyl phthalate), can elicit dose-additive effects when administered as a mixture. JF - Toxicological Sciences AU - Howdeshell, Kembra L AU - Furr, Johnathan AU - Lambright, Christy R AU - Rider, Cynthia V AU - Wilson, Vickie S AU - Gray, LEarl Jr AD - North Carolina State University, Department of Molecular Biomedical Sciences, Raleigh, North Carolina 27606. U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Reproductive Toxicology Division (MD-72), Endocrinology Branch, Research Triangle Park, North Carolina 27711 Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 190 EP - 202 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 99 IS - 1 SN - 1096-6080, 1096-6080 KW - Genetics Abstracts; Toxicology Abstracts KW - INSL3 gene KW - Testes KW - Ligaments KW - phthalate esters KW - Data processing KW - Plasticizers KW - Metabolites KW - Steroid hormones KW - Sex differentiation KW - Fetuses KW - Reproductive system KW - Pregnancy KW - Phthalic acid KW - Testosterone KW - Gestation KW - Polymerase chain reaction KW - Progeny KW - G 07730:Development & Cell Cycle KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19882986?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Cumulative+Effects+of+Dibutyl+Phthalate+and+Diethylhexyl+Phthalate+on+Male+Rat+Reproductive+Tract+Development%3A+Altered+Fetal+Steroid+Hormones+and+Genes&rft.au=Howdeshell%2C+Kembra+L%3BFurr%2C+Johnathan%3BLambright%2C+Christy+R%3BRider%2C+Cynthia+V%3BWilson%2C+Vickie+S%3BGray%2C+LEarl+Jr&rft.aulast=Howdeshell&rft.aufirst=Kembra&rft.date=2007-09-01&rft.volume=99&rft.issue=1&rft.spage=190&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Testes; INSL3 gene; Ligaments; Data processing; phthalate esters; Plasticizers; Metabolites; Steroid hormones; Sex differentiation; Reproductive system; Fetuses; Phthalic acid; Pregnancy; Testosterone; Gestation; Polymerase chain reaction; Progeny ER - TY - JOUR T1 - Using ultrafiltration to concentrate and detect Bacillus anthracis, Bacillus atrophaeus subspecies globigii, and Cryptosporidium parvum in 100-liter water samples AN - 19855607; 7551902 AB - A strategy that uses ultrafiltration (UF) to concentrate microorganisms from water samples has been developed and tested. This strategy was tested using 100-liter water samples with volume reduction achieved through ultrafiltration and recycling the microorganisms of interest through a retentate vessel, rather than returning them to the sample container, where they might pose an incremental hazard to sample takers or the environment. Three protocols based on this strategy were tested. The first protocol entailed sample volume reduction and collection of the final reduced sample. The second and third protocols both incorporated pretreatment of the filter and fluid lines with a solution to prevent microorganisms from adhering. In the second protocol, the filter was back flushed with a surfactant solution to recover microorganisms. The third protocol used recirculation of a surfactant solution to recover microorganisms. Tests were undertaken using 100-liter water samples spiked with approximately 100 or 1000 microorganisms (1 or 10 per liter). Test microorganisms included Bacillus anthracis Sterne strain, Bacillus atrophaeus subsp. globigii, and Cryptosporidium parvum. The first protocol had significantly lower recovery than the other two. Back flushing resulted in higher recovery than forward flushing, but the difference was not statistically significant. JF - Journal of Microbiological Methods AU - Lindquist, HDA AU - Harris, S AU - Lucas, S AU - Hartzel, M AU - Riner, D AU - Rochele, P AU - DeLeon, R AD - Office of Research and Development, U.S. Environmental Protection Agency, Cincinnati, OH, United States, Lindquist.alan@epa.gov Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 484 EP - 492 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 70 IS - 3 SN - 0167-7012, 0167-7012 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; Water Resources Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Testing Procedures KW - Ultrafiltration KW - Water Analysis KW - Water Sampling KW - Statistical analysis KW - Bacillus anthracis KW - Recycling KW - Cryptosporidium parvum KW - Filters KW - Pollutants KW - Cryptosporidium KW - Microorganisms KW - Bacillus KW - Surfactants KW - SW 0810:General KW - K 03300:Methods KW - A 01300:Methods KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19855607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=Using+ultrafiltration+to+concentrate+and+detect+Bacillus+anthracis%2C+Bacillus+atrophaeus+subspecies+globigii%2C+and+Cryptosporidium+parvum+in+100-liter+water+samples&rft.au=Lindquist%2C+HDA%3BHarris%2C+S%3BLucas%2C+S%3BHartzel%2C+M%3BRiner%2C+D%3BRochele%2C+P%3BDeLeon%2C+R&rft.aulast=Lindquist&rft.aufirst=HDA&rft.date=2007-09-01&rft.volume=70&rft.issue=3&rft.spage=484&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2007.06.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Filters; Ultrafiltration; Statistical analysis; Microorganisms; Recycling; Surfactants; Testing Procedures; Pollutants; Water Analysis; Cryptosporidium; Water Sampling; Bacillus; Bacillus anthracis; Cryptosporidium parvum DO - http://dx.doi.org/10.1016/j.mimet.2007.06.007 ER - TY - JOUR T1 - Toward a Checklist for Exchange and Interpretation of Data from a Toxicology Study AN - 19747088; 7561131 AB - Data from toxicology and toxicogenomics studies are valuable, and can be combined for meta-analysis using public data repositories such as Chemical Effects in Biological Systems Knowledgebase, ArrayExpress, and Gene Expression Omnibus. In order to fully utilize the data for secondary analysis, it is necessary to have a description of the study and good annotation of the accompanying data. This study annotation permits sophisticated cross-study comparison and analysis, and allows data from comparable subjects to be identified and fully understood. The Minimal Information About a Microarray Experiment Standard was proposed to permit deposition and sharing of microarray data. We propose the first step toward an analogous standard for a toxicogenomics/toxicology study, by describing a checklist of information that best practices would suggest be included with the study data. When the information in this checklist is deposited together with the study data, the checklist information helps the public explore the study data in context of time, or identify data from similarly treated subjects, and also explore/identify potential sources of experimental variability. The proposed checklist summarizes useful information to include when sharing study data for publication, deposition into a database, or electronic exchange with collaborators. It is not a description of how to carry out an experiment, but a definition of how to describe an experiment. It is anticipated that once a toxicology checklist is accepted and put into use, then toxicology databases can be configured to require and output these fields, making it straightforward to annotate data for interpretation by others. JF - Toxicological Sciences AU - Fostel, Jennifer M AU - Burgoon, Lyle AU - Zwickl, Craig AU - Lord, Peter AU - Corton, JChristopher AU - Bushel, Pierre R AU - Cunningham, Michael AU - Fan, Liju AU - Edwards, Stephen W AU - Hester, Susan AU - Stevens, James AU - Tong, Weida AU - Waters, Michael AU - Yang, ChiHae AU - Tennant, Raymond AD - NIEHS, LMIT ITSS Contract, Research Triangle Park, North Carolina 27709-2233. Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824. Lilly Research Laboratory, Greenfield, Indiana 46140. Johnson and Johnson PRD, Raritan, New Jersey 08869. National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711. NIEHS, Research Triangle Park, North Carolina 27709-2233. National Toxicology Program, Research Triangle Park, North Carolina 27709. Ontology Workshop, LLC, Columbia, Maryland 21045-9998. National Center for Toxicological Research, Jefferson, Arkansas 72079. Integrated Life Sciences, Research Triangle Park, North Carolina 27709. Leadscope, Columbus, Ohio 43212 Y1 - 2007/09// PY - 2007 DA - Sep 2007 SP - 26 EP - 34 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK, [mailto:jnl.samples@oup.co.uk], [URL:http://www3.oup.co.uk/jnls/] VL - 99 IS - 1 SN - 1096-6080, 1096-6080 KW - Toxicology Abstracts KW - Gene expression KW - Databases KW - Data processing KW - Reviews KW - Check lists KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19747088?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+Sciences&rft.atitle=Toward+a+Checklist+for+Exchange+and+Interpretation+of+Data+from+a+Toxicology+Study&rft.au=Fostel%2C+Jennifer+M%3BBurgoon%2C+Lyle%3BZwickl%2C+Craig%3BLord%2C+Peter%3BCorton%2C+JChristopher%3BBushel%2C+Pierre+R%3BCunningham%2C+Michael%3BFan%2C+Liju%3BEdwards%2C+Stephen+W%3BHester%2C+Susan%3BStevens%2C+James%3BTong%2C+Weida%3BWaters%2C+Michael%3BYang%2C+ChiHae%3BTennant%2C+Raymond&rft.aulast=Fostel&rft.aufirst=Jennifer&rft.date=2007-09-01&rft.volume=99&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Toxicological+Sciences&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Gene expression; Databases; Data processing; Reviews; Check lists ER - TY - JOUR T1 - The influence of valley plugs in channelized streams on floodplain sedimentation dynamics over the last century AN - 1015461173; 2012-048968 JF - Wetlands (Wilmington, NC) AU - Pierce, Aaron R AU - King, Sammy L AU - Kentula, Mary E Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 631 EP - 643 PB - Springer for The Society of Wetland Scientists, Wilmington, NC VL - 27 IS - 3 SN - 0277-5212, 0277-5212 KW - United States KW - Haywood County Tennessee KW - human activity KW - floodplains KW - statistical analysis KW - sedimentation KW - channels KW - western Tennessee KW - vegetation KW - rivers KW - Madison County Tennessee KW - Hardeman County Tennessee KW - fluvial sedimentation KW - environmental effects KW - channelization KW - deposition KW - sedimentation rates KW - Tennessee KW - fluvial features KW - geomorphology KW - Hatchie River watershed KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1015461173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Wetlands+%28Wilmington%2C+NC%29&rft.atitle=The+influence+of+valley+plugs+in+channelized+streams+on+floodplain+sedimentation+dynamics+over+the+last+century&rft.au=Pierce%2C+Aaron+R%3BKing%2C+Sammy+L%3BKentula%2C+Mary+E&rft.aulast=Pierce&rft.aufirst=Aaron&rft.date=2007-09-01&rft.volume=27&rft.issue=3&rft.spage=631&rft.isbn=&rft.btitle=&rft.title=Wetlands+%28Wilmington%2C+NC%29&rft.issn=02775212&rft_id=info:doi/10.1672%2F0277-5212%282007%29272.0.CO%3B2 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2012-01-01 N1 - Number of references - 57 N1 - PubXState - NC N1 - Document feature - illus. incl. 3 tables, sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - channelization; channels; deposition; environmental effects; floodplains; fluvial features; fluvial sedimentation; geomorphology; Hardeman County Tennessee; Hatchie River watershed; Haywood County Tennessee; human activity; Madison County Tennessee; rivers; sedimentation; sedimentation rates; statistical analysis; Tennessee; United States; vegetation; western Tennessee DO - http://dx.doi.org/10.1672/0277-5212(2007)27[631:TIOVPI]2.0.CO;2 ER - TY - JOUR T1 - Assessment of wetlands in the upper Juniata watershed in Pennsylvania, USA using the hydrogeomorphic approach AN - 1015461165; 2012-048967 JF - Wetlands (Wilmington, NC) AU - Wardrop, Denice H AU - Kentula, Mary E AU - Jensen, Susan F AU - Stevens, Donald L, Jr AU - Hychka, Kristen C AU - Brooks, Robert P Y1 - 2007/09// PY - 2007 DA - September 2007 SP - 432 EP - 445 PB - Springer for The Society of Wetland Scientists, Wilmington, NC VL - 27 IS - 3 SN - 0277-5212, 0277-5212 KW - United States KW - hydrology KW - water storage KW - water quality KW - land cover KW - Juniata River KW - human activity KW - rivers and streams KW - watersheds KW - pollution KW - central Pennsylvania KW - suspended materials KW - environmental analysis KW - environmental effects KW - biochemical oxygen demand KW - classification KW - sediments KW - eutrophication KW - acidification KW - turbidity KW - ecology KW - geomorphology KW - Pennsylvania KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1015461165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Wetlands+%28Wilmington%2C+NC%29&rft.atitle=Assessment+of+wetlands+in+the+upper+Juniata+watershed+in+Pennsylvania%2C+USA+using+the+hydrogeomorphic+approach&rft.au=Wardrop%2C+Denice+H%3BKentula%2C+Mary+E%3BJensen%2C+Susan+F%3BStevens%2C+Donald+L%2C+Jr%3BHychka%2C+Kristen+C%3BBrooks%2C+Robert+P&rft.aulast=Wardrop&rft.aufirst=Denice&rft.date=2007-09-01&rft.volume=27&rft.issue=3&rft.spage=432&rft.isbn=&rft.btitle=&rft.title=Wetlands+%28Wilmington%2C+NC%29&rft.issn=02775212&rft_id=info:doi/10.1672%2F0277-5212%282007%29272.0.CO%3B2 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2012-01-01 N1 - Number of references - 35 N1 - PubXState - NC N1 - Document feature - illus. incl. 6 tables, sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - acidification; biochemical oxygen demand; central Pennsylvania; classification; ecology; environmental analysis; environmental effects; eutrophication; geomorphology; human activity; hydrology; Juniata River; land cover; Pennsylvania; pollution; rivers and streams; sediments; suspended materials; turbidity; United States; water quality; water storage; watersheds DO - http://dx.doi.org/10.1672/0277-5212(2007)27[432:AOWITU]2.0.CO;2 ER - TY - JOUR T1 - Science, policy, and trends of metals risk assessment at EPA: How understanding metals bioavailability has changed metals risk assessment at US EPA AN - 19294935; 7547221 AB - The US Environmental Protection Agency (EPA) and the Office of Water have made significant changes in the approaches taken to assessing metals in the aquatic environment. Over the last 20 years, the Office of Water has progressed through a variety of metals assessment tools from total recoverable metal to the biotic ligand model. These changes were initially driven by the recognition that the total metals criteria were out of date and that emerging science would make it possible to address bioavailability more thoroughly. More recent drivers are expectations that the agency ensure the criteria are protective of endangered species and that the agency can bring the best available science to conducting total maximum daily loads (TMDLs) for waters not meeting uses because of metal contamination. Changes have included: moving from total recoverable metals concentration to dissolved metals and the development of dissolved metal to total metal translator guidance, the development of water effect ratios (WERs) guidance, and most recently incorporation of the biotic ligand model (BLM) into criteria derivation for aquatic life protection (USEPA, 2007a. Aquatic Life Ambient Freshwater Quality Criteria-Copper 2007 Revision. EPA-822-R-07-001. http://www.epa.gov/waterscience /criteria/copper/index.htm.). On March 8, 2007, the agency published its Framework for Metals Risk Assessment (USEPA, 2007b. Framework for Metals Risk Assessment. EPA 120/R-07/001. http://www.epa.gov /osa/metalsframework.) discussing the state of the science for the persistent bioaccumulative, and toxic nature of metals and the considerations of this science that will impact many programs. This paper provides a brief insight to these agency activities. JF - Aquatic Toxicology AU - Reiley, M C AD - Office of Water, MC-4304T, 1200 Pennsylvania Avenue, NW, Washington, DC 20460, USA, reiley.mary@epa.gov Y1 - 2007/08/30/ PY - 2007 DA - 2007 Aug 30 SP - 292 EP - 298 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl] VL - 84 IS - 2 SN - 0166-445X, 0166-445X KW - Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Toxicology Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Risk assessment KW - Contamination KW - Heavy metals KW - Pollution effects KW - Copper KW - Models KW - Bioavailability KW - Assessments KW - Varieties KW - Pollutant persistence KW - Metals KW - Policies KW - Conferences KW - Freshwater environments KW - Aquatic Life KW - science policy KW - Environmental impact KW - Rare species KW - Aquatic environment KW - Model Studies KW - Risk KW - EPA KW - USA KW - Bioaccumulation KW - Water Pollution Effects KW - Endangered species KW - Ligands KW - P 9000:ENVIRONMENTAL ACTION KW - Q5 08504:Effects on organisms KW - SW 3030:Effects of pollution KW - AQ 00008:Effects of Pollution KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19294935?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Toxicology&rft.atitle=Science%2C+policy%2C+and+trends+of+metals+risk+assessment+at+EPA%3A+How+understanding+metals+bioavailability+has+changed+metals+risk+assessment+at+US+EPA&rft.au=Reiley%2C+M+C&rft.aulast=Reiley&rft.aufirst=M&rft.date=2007-08-30&rft.volume=84&rft.issue=2&rft.spage=292&rft.isbn=&rft.btitle=&rft.title=Aquatic+Toxicology&rft.issn=0166445X&rft_id=info:doi/10.1016%2Fj.aquatox.2007.05.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Policies; Bioaccumulation; Heavy metals; Pollutant persistence; Environmental impact; Pollution effects; Rare species; Ligands; Risk assessment; Bioavailability; Contamination; Conferences; Freshwater environments; Endangered species; Copper; Aquatic environment; Models; EPA; Metals; science policy; Risk; Assessments; Aquatic Life; Water Pollution Effects; Varieties; Model Studies; USA DO - http://dx.doi.org/10.1016/j.aquatox.2007.05.014 ER - TY - CPAPER T1 - Evaluation of Potential False Negative Corrosive Chemicals in Proposed In Vitro Dermal Irritation Assays T2 - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AN - 39593145; 4721449 JF - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AU - Rispin, Amy Y1 - 2007/08/21/ PY - 2007 DA - 2007 Aug 21 KW - Corrosion KW - Chemicals KW - Irritation KW - Skin KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39593145?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.atitle=Evaluation+of+Potential+False+Negative+Corrosive+Chemicals+in+Proposed+In+Vitro+Dermal+Irritation+Assays&rft.au=Rispin%2C+Amy&rft.aulast=Rispin&rft.aufirst=Amy&rft.date=2007-08-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.issn=&rft_id=info:doi/ L2 - http://www.ech.co.jp/wc6/pdf/wc6_session.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In Vitro Cytotoxicity Test Methods for Estimating Starting Doses for Rat Acute Oral Toxicity Tests: Impact on Animal Savings T2 - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AN - 39579414; 4721760 JF - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AU - Rispin, Amy Y1 - 2007/08/21/ PY - 2007 DA - 2007 Aug 21 KW - Toxicity testing KW - Cytotoxicity KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39579414?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.atitle=In+Vitro+Cytotoxicity+Test+Methods+for+Estimating+Starting+Doses+for+Rat+Acute+Oral+Toxicity+Tests%3A+Impact+on+Animal+Savings&rft.au=Rispin%2C+Amy&rft.aulast=Rispin&rft.aufirst=Amy&rft.date=2007-08-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.issn=&rft_id=info:doi/ L2 - http://www.ech.co.jp/wc6/pdf/wc6_session.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - ICCVAM Recommendations for the Use of In Vitro Test Methods for the Identification and Classification of Ocular Corrosives and Severe Irritants T2 - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AN - 39576130; 4721765 JF - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AU - Hamernik, Karen Y1 - 2007/08/21/ PY - 2007 DA - 2007 Aug 21 KW - Corrosion KW - Classification KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39576130?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.atitle=ICCVAM+Recommendations+for+the+Use+of+In+Vitro+Test+Methods+for+the+Identification+and+Classification+of+Ocular+Corrosives+and+Severe+Irritants&rft.au=Hamernik%2C+Karen&rft.aulast=Hamernik&rft.aufirst=Karen&rft.date=2007-08-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.issn=&rft_id=info:doi/ L2 - http://www.ech.co.jp/wc6/pdf/wc6_session.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - USEPAs ToxCast Program for Predicting Hazard and Prioritizing Toxicity Testing of Environmental Chemicals T2 - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AN - 39567503; 4721557 JF - 6th World Congress on Alternatives Animal Use in the Life Sciences (WC6) AU - Kavlock, Robert J Y1 - 2007/08/21/ PY - 2007 DA - 2007 Aug 21 KW - Toxicity testing KW - Chemicals KW - Bioaccumulation KW - Pollution indicators KW - Hazards KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39567503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.atitle=USEPAs+ToxCast+Program+for+Predicting+Hazard+and+Prioritizing+Toxicity+Testing+of+Environmental+Chemicals&rft.au=Kavlock%2C+Robert+J&rft.aulast=Kavlock&rft.aufirst=Robert&rft.date=2007-08-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=6th+World+Congress+on+Alternatives+Animal+Use+in+the+Life+Sciences+%28WC6%29&rft.issn=&rft_id=info:doi/ L2 - http://www.ech.co.jp/wc6/pdf/wc6_session.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - TSCA: How it Affects Academic Institutions T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39450922; 4632642 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Toscano, Rose Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Waste management KW - Environmental regulations KW - RCRA KW - Government regulations KW - Hazardous wastes KW - Legislation KW - Federal regulations KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39450922?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=TSCA%3A+How+it+Affects+Academic+Institutions&rft.au=Toscano%2C+Rose&rft.aulast=Toscano&rft.aufirst=Rose&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of Pesticide Volatile Organic Compound (VOC) Emission Adjustment Factors T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39441531; 4636326 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Barry, Terrell A AU - Segawa, Randy Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Volatile organic compounds KW - Pesticides KW - Emissions KW - Organic compounds KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39441531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Development+of+Pesticide+Volatile+Organic+Compound+%28VOC%29+Emission+Adjustment+Factors&rft.au=Barry%2C+Terrell+A%3BSegawa%2C+Randy&rft.aulast=Barry&rft.aufirst=Terrell&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assessing As, Hg and Se Speciation and Transport in Flue Gas Desulphurization Material and Drywall T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39440810; 4633743 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Al-Abed, Souhail R AU - Jegadeesan, Gautham AU - Scheckel, Kirk G Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Flue gas KW - Speciation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39440810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Assessing+As%2C+Hg+and+Se+Speciation+and+Transport+in+Flue+Gas+Desulphurization+Material+and+Drywall&rft.au=Al-Abed%2C+Souhail+R%3BJegadeesan%2C+Gautham%3BScheckel%2C+Kirk+G&rft.aulast=Al-Abed&rft.aufirst=Souhail&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Elucidating the Role of Electron Transfer Mediators in Reductive Transformations in Natural Sediments T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39437345; 4633618 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Zhang, Huichun AU - Weber, Eric J Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Sediment chemistry KW - Transformation KW - Electron transfer KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39437345?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Elucidating+the+Role+of+Electron+Transfer+Mediators+in+Reductive+Transformations+in+Natural+Sediments&rft.au=Zhang%2C+Huichun%3BWeber%2C+Eric+J&rft.aulast=Zhang&rft.aufirst=Huichun&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Hydrogenation of Polycyclic Aromatic Compounds using Ni Supported on H"-Zeolite as Catalysts in Supercritical Carbon Dioxide T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39428699; 4633795 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Sahle-Demessie, E. AU - Devulapelli, Venugopal Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Catalysts KW - Aromatic compounds KW - Carbon dioxide KW - Hydrogenation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39428699?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Hydrogenation+of+Polycyclic+Aromatic+Compounds+using+Ni+Supported+on+H%22-Zeolite+as+Catalysts+in+Supercritical+Carbon+Dioxide&rft.au=Sahle-Demessie%2C+E.%3BDevulapelli%2C+Venugopal&rft.aulast=Sahle-Demessie&rft.aufirst=E.&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Carbon Nanotubes in Microwave Environment-Ignition and Reconstruction T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39417246; 4633500 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Nadagouda, Mallikarjuna N AU - Varma, Rajender S Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Nanotechnology KW - Carbon KW - Nanotubes KW - Microwave radiation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39417246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Carbon+Nanotubes+in+Microwave+Environment-Ignition+and+Reconstruction&rft.au=Nadagouda%2C+Mallikarjuna+N%3BVarma%2C+Rajender+S&rft.aulast=Nadagouda&rft.aufirst=Mallikarjuna&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bulk and Template-free Synthesis of Silver Nanowires Using Caffeine at Room Temperature T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39395336; 4629580 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Nadagouda, Mallikarjuna N AU - Varma, Rajender S Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Temperature effects KW - Silver KW - Caffeine KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39395336?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Bulk+and+Template-free+Synthesis+of+Silver+Nanowires+Using+Caffeine+at+Room+Temperature&rft.au=Nadagouda%2C+Mallikarjuna+N%3BVarma%2C+Rajender+S&rft.aulast=Nadagouda&rft.aufirst=Mallikarjuna&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - AGRO Membership Trends and Plans T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39373891; 4636391 DE: JF - 234th National Meeting and Exposition of the American Chemical Society AU - Stout II, Daniel M Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39373891?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=AGRO+Membership+Trends+and+Plans&rft.au=Stout+II%2C+Daniel+M&rft.aulast=Stout+II&rft.aufirst=Daniel&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Utilizing in Silico Techniques to Elucidate the Stereoselective Behavior of Pyrethroids within Carboxylesterase T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39373847; 4636363 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Chang, Daniel T AU - Goldsmith, Michael-Rock AU - Tornero-Velez, Rogelio AU - Rabinowitz, James AU - Dary, Curtis C Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Pyrethroids KW - Carboxylesterase KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39373847?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Utilizing+in+Silico+Techniques+to+Elucidate+the+Stereoselective+Behavior+of+Pyrethroids+within+Carboxylesterase&rft.au=Chang%2C+Daniel+T%3BGoldsmith%2C+Michael-Rock%3BTornero-Velez%2C+Rogelio%3BRabinowitz%2C+James%3BDary%2C+Curtis+C&rft.aulast=Chang&rft.aufirst=Daniel&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mechanisms of Heavy Metal Removal from Acid Mine Drainage using Chitin T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39369629; 4637730 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Al-Abed, Souhail R AU - Reisman, David J AU - Deshpande, Niranjan AU - Jegadeesan, Gautham Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Heavy metals KW - Chitin KW - Acidic wastes KW - Mine tailings KW - Drainage KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39369629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Mechanisms+of+Heavy+Metal+Removal+from+Acid+Mine+Drainage+using+Chitin&rft.au=Al-Abed%2C+Souhail+R%3BReisman%2C+David+J%3BDeshpande%2C+Niranjan%3BJegadeesan%2C+Gautham&rft.aulast=Al-Abed&rft.aufirst=Souhail&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of Organic Markers for Identifying Sources of Human Exposure to Airborne Fine Particulate Matter T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39366770; 4633636 JF - 234th National Meeting and Exposition of the American Chemical Society AU - McDow, Stephen R AU - Turlington, John AU - Olson, David AU - Stockburger, Leonard AU - Tong-Argao, Sania Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Particulate matter KW - Suspended particulate matter KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39366770?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Analysis+of+Organic+Markers+for+Identifying+Sources+of+Human+Exposure+to+Airborne+Fine+Particulate+Matter&rft.au=McDow%2C+Stephen+R%3BTurlington%2C+John%3BOlson%2C+David%3BStockburger%2C+Leonard%3BTong-Argao%2C+Sania&rft.aulast=McDow&rft.aufirst=Stephen&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Enantioselective Formation of the Triazole Fungicide Triadimenol from Triadimefon in Mammal and Fish Hepatic Microsomes T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39332451; 4636366 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Kenneke, John F AU - Mazur, Christopher S AU - Garrison, A Wayne Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Fungicides KW - Mammals KW - Triazoles KW - Enantiomers KW - Triadimenol KW - Microsomes KW - Liver KW - Triadimefon KW - Ribosomes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39332451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Enantioselective+Formation+of+the+Triazole+Fungicide+Triadimenol+from+Triadimefon+in+Mammal+and+Fish+Hepatic+Microsomes&rft.au=Kenneke%2C+John+F%3BMazur%2C+Christopher+S%3BGarrison%2C+A+Wayne&rft.aulast=Kenneke&rft.aufirst=John&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Catalytic Oxidation of Dimethyl Sulfide with Ozone and the Effect of Promoter and Physico-Chemical Properties of Metal Oxide Catalysts T2 - 234th National Meeting and Exposition of the American Chemical Society AN - 39329826; 4637708 JF - 234th National Meeting and Exposition of the American Chemical Society AU - Devulapelli, Venugopal AU - Sahle-Demessie, E. Y1 - 2007/08/19/ PY - 2007 DA - 2007 Aug 19 KW - Physicochemical properties KW - Sulfide KW - Ozone KW - Oxidation KW - Catalysts KW - Metals KW - Promoters KW - Oxides KW - Dimethyl sulfide KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39329826?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.atitle=Catalytic+Oxidation+of+Dimethyl+Sulfide+with+Ozone+and+the+Effect+of+Promoter+and+Physico-Chemical+Properties+of+Metal+Oxide+Catalysts&rft.au=Devulapelli%2C+Venugopal%3BSahle-Demessie%2C+E.&rft.aulast=Devulapelli&rft.aufirst=Venugopal&rft.date=2007-08-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=234th+National+Meeting+and+Exposition+of+the+American+Chemical+Society&rft.issn=&rft_id=info:doi/ L2 - http://oasys2.confex.com/acs/234nm/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Estimation of chemical toxicity to wildlife species using interspecies correlation models. AN - 68283448; 17874802 AB - Ecological risks to wildlife are typically assessed using toxicity data for relatively few species and with limited understanding of differences in species sensitivity to contaminants. Empirical interspecies correlation models were derived from LD50 values for 49 wildlife species and 951 chemicals. The standard wildlife test species Japanese quail (Coturnix japonica) and mallard (Anas platyrhynchos) were determined to be good surrogates for many species within the database. Cross-validation of all models predicted toxicity values within 5-fold and 10-fold of the actual values with 85 and 95% certainty, respectively. Model robustness was not consistently improved by developing correlation models within modes of action (MOA); however, improved models for neurotoxicants, carbamates, and direct acting organophosphorous acetylcholenesterase inhibiting compounds indicate that toxicity estimates may improve if MOA-specific models are built with robust datasets. There was a strong relationship between taxonomic distance and cross-validation prediction success (chi2 = 297, df = 12, p < 0.0001), with uncertainty increasing with larger taxonomic distance between the surrogate and predicted species. Interspecies toxicity correlations provide a tool for estimating contaminant sensitivity with known levels of uncertainty for a diversity of wildlife species. JF - Environmental science & technology AU - Raimondo, S AU - Mineau, P AU - Barron, M G AD - U.S. Environmental Protection Agency, National Health and Environmental Effects Laboratory, Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, Florida 32561, USA. raimondo.sandy@epa.gov Y1 - 2007/08/15/ PY - 2007 DA - 2007 Aug 15 SP - 5888 EP - 5894 VL - 41 IS - 16 SN - 0013-936X, 0013-936X KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - Animals KW - Reproducibility of Results KW - Species Specificity KW - Environmental Pollutants -- toxicity KW - Animals, Wild -- metabolism KW - Models, Biological UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68283448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+%26+technology&rft.atitle=Estimation+of+chemical+toxicity+to+wildlife+species+using+interspecies+correlation+models.&rft.au=Raimondo%2C+S%3BMineau%2C+P%3BBarron%2C+M+G&rft.aulast=Raimondo&rft.aufirst=S&rft.date=2007-08-15&rft.volume=41&rft.issue=16&rft.spage=5888&rft.isbn=&rft.btitle=&rft.title=Environmental+science+%26+technology&rft.issn=0013936X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-10 N1 - Date created - 2007-09-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Comparison of mold concentrations quantified by MSQPCR in indoor and outdoor air sampled simultaneously AN - 20842292; 7500454 AB - Mold specific quantitative PCR (MSQPCR) was used to measure the concentrations of the 36 mold species in indoor and outdoor air samples that were taken simultaneously for 48 h in and around 17 homes in Cincinnati, Ohio. The total spore concentrations of 353 per m super(3) of indoor air and 827 per m super(3) of outdoor air samples were significantly different (p approximately equal to 0.05). However, only the concentrations of Aspergillus penicillioides, Cladosporium cladosporioides types 1 and 2 and Cladosporium herbarum were correlated in indoor and outdoor air samples (p-value approximately equal to 0.05 and sufficient data for estimate and absolute value rho estimate >=0.5). These results suggest that interpretation of the meaning of short-term (<48 h) mold measurements in indoor and outdoor air samples must be made with caution. JF - Science of the Total Environment AU - Meklin, T AU - Reponen, T AU - McKinstry, C AU - Cho, SH AU - Grinshpun, SA AU - Nevalainen, A AU - Vepsalainen, A AU - Haugland, R A AU - LeMasters, G AU - Vesper, S J AD - 26 W. Ml. L. King Drive, Cincinnati, Ohio, USA, vesper.stephen@epa.gov Y1 - 2007/08/15/ PY - 2007 DA - 2007 Aug 15 SP - 130 EP - 134 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 382 IS - 1 SN - 0048-9697, 0048-9697 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology; Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Cladosporium cladosporioides KW - Aspergillus penicillioides KW - Data processing KW - USA, Ohio, Cincinnati KW - Air sampling KW - Indoor air KW - Molds KW - Polymerase chain reaction KW - Spores KW - Cladosporium herbarum KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - K 03450:Ecology KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20842292?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Science+of+the+Total+Environment&rft.atitle=Comparison+of+mold+concentrations+quantified+by+MSQPCR+in+indoor+and+outdoor+air+sampled+simultaneously&rft.au=Meklin%2C+T%3BReponen%2C+T%3BMcKinstry%2C+C%3BCho%2C+SH%3BGrinshpun%2C+SA%3BNevalainen%2C+A%3BVepsalainen%2C+A%3BHaugland%2C+R+A%3BLeMasters%2C+G%3BVesper%2C+S+J&rft.aulast=Meklin&rft.aufirst=T&rft.date=2007-08-15&rft.volume=382&rft.issue=1&rft.spage=130&rft.isbn=&rft.btitle=&rft.title=Science+of+the+Total+Environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2007.03.031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Data processing; Polymerase chain reaction; Molds; Spores; Indoor air; Air sampling; Cladosporium cladosporioides; Aspergillus penicillioides; Cladosporium herbarum; USA, Ohio, Cincinnati DO - http://dx.doi.org/10.1016/j.scitotenv.2007.03.031 ER - TY - JOUR T1 - Evaluation of groundwater flow patterns around a dual-screened groundwater circulation well AN - 1270039316; 2013-008686 AB - Dual-screened groundwater circulation wells (GCWs) can be used to remove contaminant mass and to mix reagents in situ. GCWs are so named because they force water in a circular pattern between injection and extraction screens. The radial extent, flux and direction of the effective flow of this circulation cell are difficult to measure or predict. The objective of this study is to develop a robust protocol for assessing GCW performance. To accomplish this, groundwater flow patterns surrounding a GCW are assessed using a suite of tools and data, including: hydraulic head, in situ flow velocity, measured hydraulic conductivity data from core samples, chemical tracer tests, contaminant distribution data, and numerical flow and transport models. The hydraulic head data show patterns that are consistent with pumping on a dual-screened well, however, many of the observed changes are smaller than expected. In situ thermal perturbation flow sensors successfully measured horizontal flow, but vertical flow could not be determined with sufficient accuracy to be useful in mapping flow patterns. Two types of chemical tracer tests were utilized at the site and showed that much of the flow occurs within a few meters of the GCW. Flow patterns were also assessed based on changes in contaminant (trichloroethylene, TCE) concentrations over time. The TCE data clearly showed treated water moving away from the GCW at shallow and intermediate depths, but the circulation of that water back to the well, except very close to the well, was less clear. Detailed vertical and horizontal hydraulic conductivities were measured on 0.3 m-long sections from a continuous core from the GCW installation borehole. The measured vertical and horizontal hydraulic conductivity data were used to construct numerical flow and transport models, the results of which were compared to the head, velocity and concentration data. Taken together, the field data and modeling present a fairly consistent picture of flow and transport around the GCW. However, the time and expense associated with conducting all of those tests would be prohibitive for most sites. As a consequence, a sequential protocol for GCW characterization is presented here in which the number of tools used can be adjusted to meet the needs of individual sites. While not perfect, we believe that this approach represents the most efficient means for evaluating GCW performance. Abstract Copyright (2007) Elsevier, B.V. JF - Journal of Contaminant Hydrology AU - Johnson, Richard L AU - Simon, Michelle A Y1 - 2007/08/15/ PY - 2007 DA - 2007 Aug 15 SP - 188 EP - 202 PB - Elsevier, Amsterdam VL - 93 IS - 1-4 SN - 0169-7722, 0169-7722 KW - chlorinated hydrocarbons KW - air stripping KW - soil vapor extraction KW - hydrogeology KW - preferential flow KW - remediation KW - ground water KW - transport KW - tracers KW - halogenated hydrocarbons KW - breakthrough curves KW - water pollution KW - flowmeters KW - numerical models KW - pollutants KW - injection KW - pollution KW - MODFLOW KW - aquifers KW - organic compounds KW - heterogeneous materials KW - trichloroethylene KW - hydraulic conductivity KW - water wells KW - anisotropy KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1270039316?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Contaminant+Hydrology&rft.atitle=Evaluation+of+groundwater+flow+patterns+around+a+dual-screened+groundwater+circulation+well&rft.au=Johnson%2C+Richard+L%3BSimon%2C+Michelle+A&rft.aulast=Johnson&rft.aufirst=Richard&rft.date=2007-08-15&rft.volume=93&rft.issue=1-4&rft.spage=188&rft.isbn=&rft.btitle=&rft.title=Journal+of+Contaminant+Hydrology&rft.issn=01697722&rft_id=info:doi/10.1016%2Fj.jconhyd.2007.02.003 L2 - http://www.sciencedirect.com/science/journal/01697722 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2013-01-01 N1 - Document feature - illus. N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2013-01-17 N1 - SubjectsTermNotLitGenreText - air stripping; anisotropy; aquifers; breakthrough curves; chlorinated hydrocarbons; flowmeters; ground water; halogenated hydrocarbons; heterogeneous materials; hydraulic conductivity; hydrogeology; injection; MODFLOW; numerical models; organic compounds; pollutants; pollution; preferential flow; remediation; soil vapor extraction; tracers; transport; trichloroethylene; water pollution; water wells DO - http://dx.doi.org/10.1016/j.jconhyd.2007.02.003 ER - TY - JOUR T1 - Performance assessment and validation of a paramagnetic particle-based enzyme-linked immunosorbent assay for chlorpyrifos in agricultural runoff waters. AN - 68113737; 17616137 AB - A commercial magnetic particle-based enzyme-linked immunosorbent assay (ELISA) kit for the insecticide chlorpyrifos [O,O-diethyl-O-(3,5,6-trichloro-2-pyridyl) phosphorothioate] was evaluated for its specificity, precision, and accuracy, its susceptibility to matrix interferences in agricultural and environmental surface waters, and its comparability to a gas chromatographic/flame photometric (GC/FPD) method for the determination of organophosphorus pesticides in natural waters. Repeatability, reproducibility, and accuracy studies show that the kit satisfies current U.S. Environmental Protection Agency criteria for the assessment of analytical methods. Observable matrix effects were found to be present in all of the environmental test waters, with the slopes of calibration curves generated in each of the test matrices deviating from that of the control matrix by as much as 16%. Specificity studies indicate that the chlorpyrifos polyclonal antibody adequately differentiates the target compound from other structurally similar organophosphorus pesticides, with the exception of its methyl analogue. Cross-reactivity with chlorpyrifos-methyl was approximately 37%, while reactivity with diazinon, pyridaphenthion, diclofenthion, bromiphos-ethyl, bromiphos-methyl, pirimiphos-ethyl, and chlorpyrifos oxon ranged from 1.6 to 10.7%. Cross-reactivity with pirimiphos-methyl, 3,5,6-trichloro-2-pyridinol, diethyl phosphate, and diethyl thiophosphate was negligible (<1%). Validation of the paramagnetic particle ELISA format was accomplished using water samples from two monitoring studies that were collected, split, and analyzed directly by ELISA and by GC/FPD. Results of the two analytical methods were then compared using standard t tests, regression analysis, and differences against mean measurement (bias) plots. While the agreement between the two methods was determined to be satisfactory, ELISA exhibits consistent positive bias in environmental matrices. Several preanalysis mitigation steps were suggested that may help moderate bias, but additional study is recommended to explicate the exact factors responsible for its consistent overestimation of results. JF - Journal of agricultural and food chemistry AU - Sullivan, Jonathan J AU - Chen, Ye Grace AU - Goh, Kean S AD - California Environmental Protection Agency, Department of Pesticide Regulation, Environmental Monitoring Branch, 1001 I Street, P.O. Box 4015, Sacramento, California 95814, USA. jsullivan@cdpr.ca.gov Y1 - 2007/08/08/ PY - 2007 DA - 2007 Aug 08 SP - 6407 EP - 6416 VL - 55 IS - 16 SN - 0021-8561, 0021-8561 KW - Insecticides KW - 0 KW - Water KW - 059QF0KO0R KW - Chlorpyrifos KW - JCS58I644W KW - Index Medicus KW - Sensitivity and Specificity KW - Regression Analysis KW - Magnetics KW - Reproducibility of Results KW - Microspheres KW - Water -- analysis KW - Chlorpyrifos -- analysis KW - Agriculture KW - Enzyme-Linked Immunosorbent Assay -- methods KW - Insecticides -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68113737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Performance+assessment+and+validation+of+a+paramagnetic+particle-based+enzyme-linked+immunosorbent+assay+for+chlorpyrifos+in+agricultural+runoff+waters.&rft.au=Sullivan%2C+Jonathan+J%3BChen%2C+Ye+Grace%3BGoh%2C+Kean+S&rft.aulast=Sullivan&rft.aufirst=Jonathan&rft.date=2007-08-08&rft.volume=55&rft.issue=16&rft.spage=6407&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-19 N1 - Date created - 2007-08-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - CPAPER T1 - Inferring Temporal Trends in Stream Temperature from Changes in Biological Assemblage Composition T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39557369; 4654563 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Yuan, Lester L AU - Hubler, Shannon AU - Whitney, Larry Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Temperature effects KW - Streams KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39557369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Inferring+Temporal+Trends+in+Stream+Temperature+from+Changes+in+Biological+Assemblage+Composition&rft.au=Yuan%2C+Lester+L%3BHubler%2C+Shannon%3BWhitney%2C+Larry&rft.aulast=Yuan&rft.aufirst=Lester&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Restoring Suburban Watersheds using a Multidisciplinary Approach to Stormwater Management T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39549393; 4657265 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Roy, Allison H AU - Clagett, Matthew P AU - Morrison, Matthew A AU - Shuster, William D AU - Thurston, Hale W AU - Cabezas, Heriberto Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Watersheds KW - Water management KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39549393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Restoring+Suburban+Watersheds+using+a+Multidisciplinary+Approach+to+Stormwater+Management&rft.au=Roy%2C+Allison+H%3BClagett%2C+Matthew+P%3BMorrison%2C+Matthew+A%3BShuster%2C+William+D%3BThurston%2C+Hale+W%3BCabezas%2C+Heriberto&rft.aulast=Roy&rft.aufirst=Allison&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Towards Understanding Sea-level Rise: Interactions between Precipitation, Ocean Water Intrusion, and Coastal Dune Vegetation T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39514310; 4656140 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Greaver, Tara L AU - Sternberg, Leonel Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Sea level changes KW - Vegetation KW - Coastal zone KW - Oceans KW - Dunes KW - Precipitation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39514310?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Towards+Understanding+Sea-level+Rise%3A+Interactions+between+Precipitation%2C+Ocean+Water+Intrusion%2C+and+Coastal+Dune+Vegetation&rft.au=Greaver%2C+Tara+L%3BSternberg%2C+Leonel&rft.aulast=Greaver&rft.aufirst=Tara&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - When Isotopes Aren't Enough: Using Additional Information to Constrain Mixing Problems T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39499179; 4657430 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Phillips, Donald L AU - Schuur, Edward A G AU - Brooks, J Renee AU - Ben-David, Merav AU - Fry, Brian Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Isotopes KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39499179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=When+Isotopes+Aren%27t+Enough%3A+Using+Additional+Information+to+Constrain+Mixing+Problems&rft.au=Phillips%2C+Donald+L%3BSchuur%2C+Edward+A+G%3BBrooks%2C+J+Renee%3BBen-David%2C+Merav%3BFry%2C+Brian&rft.aulast=Phillips&rft.aufirst=Donald&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Chloride Dynamics in the Hyporheic Zone of a Flashy Urban Stream in the Chesapeake Bay Watershed T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39492495; 4655359 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Mayer, Paul AU - Striz, Elise AU - Doheny, Edward AU - Kaushal, Sujay AU - Groffman, Peter M Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - USA, Chesapeake Bay KW - Chloride KW - Watersheds KW - Streams KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39492495?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Chloride+Dynamics+in+the+Hyporheic+Zone+of+a+Flashy+Urban+Stream+in+the+Chesapeake+Bay+Watershed&rft.au=Mayer%2C+Paul%3BStriz%2C+Elise%3BDoheny%2C+Edward%3BKaushal%2C+Sujay%3BGroffman%2C+Peter+M&rft.aulast=Mayer&rft.aufirst=Paul&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of Habitat on Reproduction of the Bay Scallop, Argopecten irradians T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39490037; 4655117 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Weissberger, Eric J AU - Chintala, Marnita M Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Reproduction KW - Habitat KW - Marine molluscs KW - Abiotic factors KW - Light effects KW - Argopecten irradians KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39490037?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Effects+of+Habitat+on+Reproduction+of+the+Bay+Scallop%2C+Argopecten+irradians&rft.au=Weissberger%2C+Eric+J%3BChintala%2C+Marnita+M&rft.aulast=Weissberger&rft.aufirst=Eric&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Marine Aerosols Alter Soil Processes in Coastal Forests T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39468554; 4656633 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Compton, Jana E AU - Church, M Robbins AU - Asano, Yuko Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Soil KW - Forests KW - Aerosols KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39468554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Marine+Aerosols+Alter+Soil+Processes+in+Coastal+Forests&rft.au=Compton%2C+Jana+E%3BChurch%2C+M+Robbins%3BAsano%2C+Yuko&rft.aulast=Compton&rft.aufirst=Jana&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparisons of Macroinvertebrate Traits with Empirically Defined Environmental Preferences T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39464370; 4654564 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Pollard, Amina I AU - Yuan, Lester L Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Zoobenthos KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39464370?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Comparisons+of+Macroinvertebrate+Traits+with+Empirically+Defined+Environmental+Preferences&rft.au=Pollard%2C+Amina+I%3BYuan%2C+Lester+L&rft.aulast=Pollard&rft.aufirst=Amina&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Opening the Black Box: A Tool for Evaluating the Biological Information of a GARP Rule-Set using Examples from the Natural Ecology of Anthrax T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39459693; 4655608 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - McNyset, Kristina M AU - Blackburn, Jason K Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Anthrax KW - Ecology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39459693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Opening+the+Black+Box%3A+A+Tool+for+Evaluating+the+Biological+Information+of+a+GARP+Rule-Set+using+Examples+from+the+Natural+Ecology+of+Anthrax&rft.au=McNyset%2C+Kristina+M%3BBlackburn%2C+Jason+K&rft.aulast=McNyset&rft.aufirst=Kristina&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Ranking Scheme for High-Impact Non-Native Aquatic Invaders T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39426599; 4654477 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Von Holle, Betsy AU - Biven, Laura AU - Frithsen, Jeffrey AU - Marchetti, Michael P AU - Reichard, Sarah AU - Ricciardi, Anthony AU - Ruiz, Gregory M Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Introduced species KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39426599?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=A+Ranking+Scheme+for+High-Impact+Non-Native+Aquatic+Invaders&rft.au=Von+Holle%2C+Betsy%3BBiven%2C+Laura%3BFrithsen%2C+Jeffrey%3BMarchetti%2C+Michael+P%3BReichard%2C+Sarah%3BRicciardi%2C+Anthony%3BRuiz%2C+Gregory+M&rft.aulast=Von+Holle&rft.aufirst=Betsy&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bay Scallop (Argopecten irradians) Habitat Attributes in a Massachusetts Salt Pond with Active Scallop Restoration Efforts T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39425738; 4656282 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Chintala, Marnita M AU - Weissberger, Eric J AU - Grunden, David W Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - USA, Massachusetts KW - Caribbean Sea, Bahamas, San Salvador, Salt Pond KW - Ponds KW - Salt lakes KW - Habitat improvement KW - Marine molluscs KW - Argopecten irradians KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39425738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Bay+Scallop+%28Argopecten+irradians%29+Habitat+Attributes+in+a+Massachusetts+Salt+Pond+with+Active+Scallop+Restoration+Efforts&rft.au=Chintala%2C+Marnita+M%3BWeissberger%2C+Eric+J%3BGrunden%2C+David+W&rft.aulast=Chintala&rft.aufirst=Marnita&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Disentangling Effects of Disease and Bleaching on Corals by Fitting Population Models to Data T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39414645; 4655607 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Yee, Susan Harrell AU - Santavy, Deborah L AU - Barron, Mace G Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Bleaching KW - Corals KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39414645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Disentangling+Effects+of+Disease+and+Bleaching+on+Corals+by+Fitting+Population+Models+to+Data&rft.au=Yee%2C+Susan+Harrell%3BSantavy%2C+Deborah+L%3BBarron%2C+Mace+G&rft.aulast=Yee&rft.aufirst=Susan&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Are Invasive Riparian Plants Associated with Reduced Biotic Condition of Fauna in Western US Streams? T2 - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AN - 39414219; 4655398 JF - 92nd International Joint Annual Meeting of the Ecological Society of America and Society for Ecological Restoration AU - Ringold, Paul L AU - McNyset, Kristina M AU - Magee, Teresa AU - Van Sickle, John Y1 - 2007/08/05/ PY - 2007 DA - 2007 Aug 05 KW - Fauna KW - Streams KW - Riparian vegetation KW - Introduced species KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39414219?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.atitle=Are+Invasive+Riparian+Plants+Associated+with+Reduced+Biotic+Condition+of+Fauna+in+Western+US+Streams%3F&rft.au=Ringold%2C+Paul+L%3BMcNyset%2C+Kristina+M%3BMagee%2C+Teresa%3BVan+Sickle%2C+John&rft.aulast=Ringold&rft.aufirst=Paul&rft.date=2007-08-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=92nd+International+Joint+Annual+Meeting+of+the+Ecological+Society+of+America+and+Society+for+Ecological+Restoration&rft.issn=&rft_id=info:doi/ L2 - http://eco.confex.com/eco/2007/techprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Transcription of key genes regulating gonadal steroidogenesis in control and ketoconazole- or vinclozolin-exposed fathead minnows. AN - 70766694; 17517826 AB - This study evaluated changes in the expression of steroidogenesis-related genes in male fathead minnows exposed to ketoconazole (KTC) or vinclozolin (VZ) for 21 days. The aim was to evaluate links between molecular changes and higher level outcomes after exposure to endocrine-active chemicals (EACs) with different modes of action. To aid our analysis and interpretation of EAC-related effects, we first examined variation in the relative abundance of steroidogenesis-related gene transcripts in the gonads of male and female fathead minnows as a function of age, gonad development, and spawning status, independent of EAC exposure. Gonadal expression of several genes varied with age and/or gonadal somatic index in either males or females. However, with the exception of aromatase, steroidogenesis-related gene expression did not vary with spawning status. Following the baseline experiments, expression of the selected genes in male fathead minnows exposed to KTC or VZ was evaluated in the context of effects observed at higher levels of organization. Exposure to KTC elicited changes in gene transcription that were consistent with an apparent compensatory response to the chemical's anticipated direct inhibition of steroidogenic enzyme activity. Exposure to VZ, an antiandrogen expected to indirectly impact steroidogenesis, increased pituitary expression of follicle-stimulating hormone beta-subunit as well as testis expression of 20beta-hydroxysteroid dehydrogenase and luteinizing hormone receptor transcripts. Results of this study contribute to ongoing research aimed at understanding responses of the teleost hypothalamic-pituitary-gonadal axis to different types of EACs and how changes in molecular endpoints translate into apical outcomes reflective of either adverse effect or compensation. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Villeneuve, Daniel L AU - Blake, Lindsey S AU - Brodin, Jeffrey D AU - Greene, Katie J AU - Knoebl, Iris AU - Miracle, Ann L AU - Martinovic, Dalma AU - Ankley, Gerald T AD - U.S. Environmental Protection Agency, ORD, NHEERL, Mid-Continent Ecology Division, Duluth, Minnesota 55804, USA. villeneuve.dan@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 395 EP - 407 VL - 98 IS - 2 SN - 1096-6080, 1096-6080 KW - Antifungal Agents KW - 0 KW - Cytochromes KW - Endocrine Disruptors KW - Follicle Stimulating Hormone, beta Subunit KW - Fungicides, Industrial KW - Luteinizing Hormone, beta Subunit KW - Oxazoles KW - Phosphoproteins KW - RNA, Messenger KW - Receptors, FSH KW - Receptors, LH KW - steroidogenic acute regulatory protein KW - Hydroxysteroid Dehydrogenases KW - EC 1.1.- KW - vinclozolin KW - JJ258EZN1I KW - Ketoconazole KW - R9400W927I KW - Index Medicus KW - Animals KW - Testis -- metabolism KW - Phosphoproteins -- genetics KW - Ovary -- drug effects KW - Receptors, LH -- genetics KW - Hydroxysteroid Dehydrogenases -- genetics KW - Receptors, LH -- metabolism KW - Receptors, FSH -- genetics KW - Pituitary Gland -- drug effects KW - Endocrine Disruptors -- toxicity KW - Ovary -- metabolism KW - Testis -- drug effects KW - RNA, Messenger -- metabolism KW - Cyprinidae KW - Hydroxysteroid Dehydrogenases -- metabolism KW - Follicle Stimulating Hormone, beta Subunit -- metabolism KW - Pituitary Gland -- metabolism KW - Receptors, FSH -- metabolism KW - Cytochromes -- genetics KW - Luteinizing Hormone, beta Subunit -- metabolism KW - Female KW - Male KW - Phosphoproteins -- metabolism KW - Cytochromes -- metabolism KW - Antifungal Agents -- toxicity KW - Ketoconazole -- toxicity KW - Gene Expression Regulation -- drug effects KW - Fungicides, Industrial -- toxicity KW - Oxazoles -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70766694?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Transcription+of+key+genes+regulating+gonadal+steroidogenesis+in+control+and+ketoconazole-+or+vinclozolin-exposed+fathead+minnows.&rft.au=Villeneuve%2C+Daniel+L%3BBlake%2C+Lindsey+S%3BBrodin%2C+Jeffrey+D%3BGreene%2C+Katie+J%3BKnoebl%2C+Iris%3BMiracle%2C+Ann+L%3BMartinovic%2C+Dalma%3BAnkley%2C+Gerald+T&rft.aulast=Villeneuve&rft.aufirst=Daniel&rft.date=2007-08-01&rft.volume=98&rft.issue=2&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-19 N1 - Date created - 2007-07-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha. AN - 70751565; 17488742 AB - Perfluorooctanoic acid (PFOA) is a member of a family of perfluorinated chemicals that have a variety of applications. PFOA persists in the environment and is found in wildlife and humans. In mice, PFOA is developmentally toxic producing mortality, delayed eye opening, growth deficits, and altered pubertal maturation. PFOA activates peroxisome proliferators-activated receptor-alpha (PPARalpha), a pathway critical to the mode of induction of liver tumors in rodents. The present study uses 129S1/SvlmJ wild-type (WT) and PPARalpha knockout (KO) mice to determine if PPARalpha mediates PFOA-induced developmental toxicity. Pregnant mice were dosed orally from gestation days 1-17 with water or 0.1, 0.3, 0.6, 1, 3, 5, 10, or 20 mg PFOA/kg. PFOA did not affect maternal weight, embryonic implantation, number, or weight of pups at birth. At 5 mg/kg, the incidence of full litter resorptions increased in both WT and KO mice. In WT, but not KO, neonatal survival was reduced (0.6 mg/kg) and eye opening was delayed (1 mg/kg). There was a trend across dose for reduced pup weight (WT and KO) on several postnatal days (PND), but only WT exposed to 1 mg/kg were significantly different from control (PND7-10 and 22). Maternal factors (e.g., background genetics) did not contribute to differences in postnatal mortality, as PFOA induced postnatal mortality in heterozygous pups born to WT or KO dams. In conclusion, early pregnancy loss was independent of PPARalpha expression. Delayed eye opening and deficits in postnatal weight gain appeared to depend on PPARalpha expression, although other mechanisms may contribute. PPARalpha was required for PFOA-induced postnatal lethality and expression of one copy of the gene was sufficient to mediate this effect. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Abbott, Barbara D AU - Wolf, Cynthia J AU - Schmid, Judith E AU - Das, Kaberi P AU - Zehr, Robert D AU - Helfant, Laurence AU - Nakayama, Shoji AU - Lindstrom, Andrew B AU - Strynar, Mark J AU - Lau, Christopher AD - Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, 2525 East Highway 54, Durham, NC 27713, USA. Abbott.barbara@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 571 EP - 581 VL - 98 IS - 2 SN - 1096-6080, 1096-6080 KW - Caprylates KW - 0 KW - Fluorocarbons KW - PPAR alpha KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Mice, Inbred Strains KW - Eye -- growth & development KW - Animals KW - Liver -- growth & development KW - Liver -- drug effects KW - Mice KW - Eye -- drug effects KW - Male KW - Female KW - Pregnancy KW - Organ Size -- drug effects KW - Mice, Knockout KW - Fluorocarbons -- pharmacokinetics KW - Caprylates -- blood KW - PPAR alpha -- deficiency KW - Embryo Loss -- chemically induced KW - Fluorocarbons -- toxicity KW - Fluorocarbons -- blood KW - Caprylates -- toxicity KW - Caprylates -- pharmacokinetics KW - Embryo Loss -- blood KW - Embryo Loss -- genetics KW - PPAR alpha -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70751565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Perfluorooctanoic+acid+induced+developmental+toxicity+in+the+mouse+is+dependent+on+expression+of+peroxisome+proliferator+activated+receptor-alpha.&rft.au=Abbott%2C+Barbara+D%3BWolf%2C+Cynthia+J%3BSchmid%2C+Judith+E%3BDas%2C+Kaberi+P%3BZehr%2C+Robert+D%3BHelfant%2C+Laurence%3BNakayama%2C+Shoji%3BLindstrom%2C+Andrew+B%3BStrynar%2C+Mark+J%3BLau%2C+Christopher&rft.aulast=Abbott&rft.aufirst=Barbara&rft.date=2007-08-01&rft.volume=98&rft.issue=2&rft.spage=571&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-19 N1 - Date created - 2007-07-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Comparison of acute neurobehavioral and cholinesterase inhibitory effects of N-methylcarbamates in rat. AN - 70737090; 17504769 AB - While the cholinesterase-inhibiting N-methyl carbamate pesticides have been widely used, there are few studies evaluating direct functional and biochemical consequences of exposure. In the present study of the acute toxicity of seven N-methyl carbamate pesticides, we evaluated the dose-response profiles of cholinesterase (ChE) inhibition in brain and erythrocytes (RBCs) as well as motor activity (both horizontally and vertically directed) and clinical signs of overt toxicity. The chemicals tested were carbaryl, carbofuran, formetanate, methiocarb, methomyl, oxamyl, and propoxur. All were administered orally, and rats were tested in 20-min activity sessions beginning 15 min after dosing; tissues were collected immediately after activity sessions. In general, motor activity was a sensitive measure of ChE inhibition for all these carbamate pesticides, and vertical activity showed the greatest magnitude of effect at the highest doses compared to either horizontal activity or ChE inhibition. Brain and RBC ChE activities were generally affected similarly. Pearson correlation coefficients of within-subject data showed good correlation between the behavioral and biochemical end points, with brain ChE inhibition and horizontal activity showing the highest correlation values. Determination of benchmark dose levels for 10% change in each end point also revealed that these two measures produced the lowest estimates. Thus, motor activity decreases are highly predictive of ChE inhibition for N-methyl carbamates, and vice versa. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - McDaniel, Katherine L AU - Padilla, Stephanie AU - Marshall, Renée S AU - Phillips, Pamela M AU - Podhorniak, Lynda AU - Qian, Yaorong AU - Moser, Virginia C AD - Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 552 EP - 560 VL - 98 IS - 2 SN - 1096-6080, 1096-6080 KW - Carbamates KW - 0 KW - Cholinesterase Inhibitors KW - Cholinesterases KW - EC 3.1.1.8 KW - Index Medicus KW - Rats KW - Animals KW - Rats, Long-Evans KW - Cholinesterases -- blood KW - Dose-Response Relationship, Drug KW - Motor Activity -- drug effects KW - Male KW - Brain -- physiopathology KW - Brain -- enzymology KW - Cholinesterase Inhibitors -- toxicity KW - Brain -- drug effects KW - Carbamates -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70737090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Comparison+of+acute+neurobehavioral+and+cholinesterase+inhibitory+effects+of+N-methylcarbamates+in+rat.&rft.au=McDaniel%2C+Katherine+L%3BPadilla%2C+Stephanie%3BMarshall%2C+Ren%C3%A9e+S%3BPhillips%2C+Pamela+M%3BPodhorniak%2C+Lynda%3BQian%2C+Yaorong%3BMoser%2C+Virginia+C&rft.aulast=McDaniel&rft.aufirst=Katherine&rft.date=2007-08-01&rft.volume=98&rft.issue=2&rft.spage=552&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-19 N1 - Date created - 2007-07-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Reconstruction of contaminant trends in a salt wedge estuary with sediment cores dated using a multiple proxy approach. AN - 70675622; 17328947 AB - The Taunton River is a partially mixed tidal estuary in southeastern Massachusetts (USA) which has received significant contaminant inputs, yet little information exists on the history of discharge and the subsequent fate of these contaminants. Three sediment cores taken along a transect were analyzed, reconstructing the spatial and temporal trends of pollution in the estuary. A combination of radiometric dating, contaminant markers, and storm layers from major hurricanes were used to establish age models and sedimentation rates. Age estimates obtained from the different dating methods compared well, establishing an accurate history of contaminant release to the estuary. Polycyclic aromatic hydrocarbons (PAHs) were present in one core at depths corresponding to the early 1860s, earlier than previously established dates of introduction. Temporal and spatial trends of Cr, Cu, Hg and Pb indicated multiple sources of varying input to the river. Polychlorinated biphenyls (PCBs) were present in each of the cores from the 1930s onward, with elevated levels still present in surficial sediments at several sites. A unique organic compound, Topanol, which was produced locally was used as a tracer to track contaminant transport in the river. Tracer data indicates that contaminants are still being transported and deposited to surficial sediments at high concentrations well after their discharge. This reconstruction demonstrates the utility of using multiple dating proxies where often the sole use of radiometric dating techniques is not an option and provides insights into the fate of contaminants discharged decades ago but continue to represent environmental risks. JF - Marine environmental research AU - Cantwell, Mark G AU - King, John W AU - Burgess, Robert M AU - Appleby, Peter G AD - United States Environmental Protection Agency, Office of Research and Development, National Health Effects Environmental Research Laboratory, Atlantic Ecology Division, 27 Tarzwell Drive, Narragansett, RI 02882, USA. Cantwell.mark@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 225 EP - 246 VL - 64 IS - 2 SN - 0141-1136, 0141-1136 KW - Industrial Waste KW - 0 KW - Polycyclic Aromatic Hydrocarbons KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - Massachusetts KW - Polycyclic Aromatic Hydrocarbons -- analysis KW - Industrial Waste -- analysis KW - Polychlorinated Biphenyls -- analysis KW - Water Pollution -- analysis KW - Environmental Monitoring KW - Geologic Sediments -- chemistry KW - Rivers -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70675622?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+environmental+research&rft.atitle=Reconstruction+of+contaminant+trends+in+a+salt+wedge+estuary+with+sediment+cores+dated+using+a+multiple+proxy+approach.&rft.au=Cantwell%2C+Mark+G%3BKing%2C+John+W%3BBurgess%2C+Robert+M%3BAppleby%2C+Peter+G&rft.aulast=Cantwell&rft.aufirst=Mark&rft.date=2007-08-01&rft.volume=64&rft.issue=2&rft.spage=225&rft.isbn=&rft.btitle=&rft.title=Marine+environmental+research&rft.issn=01411136&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-24 N1 - Date created - 2007-07-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Emissions from the burning of vegetative debris in air curtain destructors. AN - 68250605; 17824286 AB - Although air curtain destructors (ACDs) have been used for quite some time to dispose of vegetative debris, relatively little in-depth testing has been conducted to quantify emissions of pollutants other than CO and particulate matter. As part of an effort to prepare for possible use of ACDs to dispose of the enormous volumes of debris generated by Hurricanes Katrina and Rita, the literature on ACD emissions was reviewed to identify potential environmental issues associated with ACD disposal of construction and demolition (C&D) debris. Although no data have been published on emissions from C&D debris combustion in an ACD, a few studies provided information on emissions from the combustion of vegetative debris. These studies are reviewed, and the results compared with studies of open burning of biomass. Combustion of vegetative debris in ACD units results in significantly lower emissions of particulate matter and CO per unit of mass of debris compared with open pile burning. The available data are not sufficient to make general estimates regarding emissions of organic or metal compounds. The highly transient nature of the ACD combustion process, a minimal degree of operational control, and significant variability in debris properties make accurate prediction of ACD emissions impossible in general. Results of scoping tests conducted in preparation for possible in-depth emissions tests demonstrate the challenges associated with sampling ACD emissions and highlight the transient nature of the process. The environmental impacts of widespread use of ACDs for disposal of vegetative debris and their potential use to reduce the volume of C&D debris in future disaster response scenarios remain a considerable gap in understanding the risks associated with debris disposal options. JF - Journal of the Air & Waste Management Association (1995) AU - Miller, C Andrew AU - Lemieux, Paul M AD - U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Research Triangle Park, NC, 27711, USA. miller.andy@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 959 EP - 967 VL - 57 IS - 8 SN - 1096-2247, 1096-2247 KW - Air Pollutants KW - 0 KW - Gases KW - Particulate Matter KW - Sulfur Dioxide KW - 0UZA3422Q4 KW - Carbon Dioxide KW - 142M471B3J KW - Carbon Monoxide KW - 7U1EE4V452 KW - Nitrous Oxide KW - K50XQU1029 KW - Nitrogen Dioxide KW - S7G510RUBH KW - Oxygen KW - S88TT14065 KW - Index Medicus KW - Gases -- analysis KW - Particulate Matter -- chemistry KW - Plants -- chemistry KW - Refuse Disposal -- methods KW - Refuse Disposal -- instrumentation KW - Incineration -- instrumentation KW - Air Pollutants -- analysis KW - Air Pollutants -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68250605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.atitle=Emissions+from+the+burning+of+vegetative+debris+in+air+curtain+destructors.&rft.au=Miller%2C+C+Andrew%3BLemieux%2C+Paul+M&rft.aulast=Miller&rft.aufirst=C&rft.date=2007-08-01&rft.volume=57&rft.issue=8&rft.spage=959&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Air+%26+Waste+Management+Association+%281995%29&rft.issn=10962247&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-10-10 N1 - Date created - 2007-09-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Workshop overview: arsenic research and risk assessment. AN - 68156542; 17336359 AB - The chronic exposure of humans through consumption of high levels of inorganic arsenic (iAs)-contaminated drinking water is associated with skin lesions, peripheral vascular disease, hypertension, and cancers. Additionally, humans are exposed to organic arsenicals when used as pesticides and herbicides (e.g., monomethylarsonic acid, dimethylarsinic acid (DMA(V)) also known as cacodylic acid). Extensive research has been conducted to characterize the adverse health effects that result from exposure to iAs and its metabolites to describe the biological pathway(s) that lead to adverse health effects. To further this effort, on May 31, 2006, the United States Environmental Protection Agency (USEPA) sponsored a meeting entitled "Workshop on Arsenic Research and Risk Assessment". The invited participants from government agencies, academia, independent research organizations and consultants were asked to present their current research. The overall focus of these research efforts has been to determine the potential human health risks due to environmental exposures to arsenicals. Pursuant in these efforts is the elucidation of a mode of action for arsenicals. This paper provides a brief overview of the workshop goals, regulatory context for arsenical research, mode of action (MOA) analysis in human health risk assessment, and the application of MOA analysis for iAs and DMA(V). Subsequent papers within this issue will present the research discussed at the workshop, ensuing discussions, and conclusions of the workshop. JF - Toxicology and applied pharmacology AU - Sams, Reeder AU - Wolf, Douglas C AU - Ramasamy, Santhini AU - Ohanian, Ed AU - Chen, Jonathan AU - Lowit, Anna AD - Integrated Risk Information System Program, National Center for Environmental Assessment, MC: B-243 01, Office of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC 27711, USA. sams.reeder@epa.gov Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 SP - 245 EP - 251 VL - 222 IS - 3 SN - 0041-008X, 0041-008X KW - Arsenicals KW - 0 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Neoplasms -- pathology KW - Arsenicals -- analysis KW - Arsenicals -- chemistry KW - Humans KW - Water Supply KW - Risk Assessment KW - Arsenic -- analysis KW - Arsenic -- toxicity KW - Arsenic -- metabolism KW - Arsenic Poisoning -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68156542?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Workshop+overview%3A+arsenic+research+and+risk+assessment.&rft.au=Sams%2C+Reeder%3BWolf%2C+Douglas+C%3BRamasamy%2C+Santhini%3BOhanian%2C+Ed%3BChen%2C+Jonathan%3BLowit%2C+Anna&rft.aulast=Sams&rft.aufirst=Reeder&rft.date=2007-08-01&rft.volume=222&rft.issue=3&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-28 N1 - Date created - 2007-08-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Molecular processes in cellular arsenic metabolism. AN - 68154391; 17397889 AB - Elucidating molecular processes that underlie accumulation, metabolism and binding of iAs and its methylated metabolites provides a basis for understanding the modes of action by which iAs acts as a toxin and a carcinogen. One approach to this problem is to construct a conceptual model that incorporates available information on molecular processes involved in the influx, metabolism, binding and efflux of arsenicals in cells. This conceptual model is initially conceived as a non-quantitative representation of critical molecular processes that can be used as a framework for experimental design and prediction. However, with refinement and incorporation of additional data, the conceptual model can be expressed in mathematical terms and should be useful for quantitative estimates of the kinetic and dynamic behavior of iAs and its methylated metabolites in cells. Development of a quantitative model will be facilitated by the availability of tools and techniques to manipulate molecular processes underlying transport of arsenicals across cell membranes or expression and activity of enzymes involved in methylation of arsenicals. This model of cellular metabolism might be integrated into more complex pharmacokinetic models for systemic metabolism of iAs and its methylated metabolites. It may also be useful in development of biologically based dose-response models describing the toxic and carcinogenic actions of arsenicals. JF - Toxicology and applied pharmacology AU - Thomas, David J AD - Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA. thomas.david@epa.gov Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 SP - 365 EP - 373 VL - 222 IS - 3 SN - 0041-008X, 0041-008X KW - Poisons KW - 0 KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Animals KW - Biotransformation KW - Humans KW - Arsenic -- pharmacokinetics KW - Poisons -- metabolism KW - Arsenic -- metabolism KW - Poisons -- pharmacokinetics KW - Cells -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68154391?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Molecular+processes+in+cellular+arsenic+metabolism.&rft.au=Thomas%2C+David+J&rft.aulast=Thomas&rft.aufirst=David&rft.date=2007-08-01&rft.volume=222&rft.issue=3&rft.spage=365&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-28 N1 - Date created - 2007-08-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Insights into the carcinogenic mode of action of arsenic. AN - 68153752; 17118416 AB - That arsenic can induce cancer in humans has been known since the late 17th century, yet how arsenic induces cancer has been the subject of numerous scientific publications. Various modes of action (MOA) have been proposed for arsenic's carcinogenicity. In this paper we review our previous studies on the ability of arsenicals to cause DNA damage, the relative inability of these arsenicals to induce point mutations, and the involvement of arsenicals in spindle disruption. We present new evidence that shows that reduced glutathione (GSH) can chemically reduce inactive pentavalent arsenicals to trivalent arsenicals which can disrupt tubulin polymerization, and show that reactive oxygen species (ROS) are most likely not involved in tubulin disruption. A hypothesis is also presented on how arsenic may induce stable chromosome aberrations (CAs) that can lead to cancer, thus supporting a role for genetic damage in the MOA for arsenic. We then propose promising areas of research that might give insight into the MOA of arsenic. JF - Toxicology and applied pharmacology AU - Kligerman, A D AU - Tennant, A H AD - Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, B143-06 US Environmental Protection Agency Research Triangle Park, NC 27711, USA. kligerman.andrew@epa.gov Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 SP - 281 EP - 288 VL - 222 IS - 3 SN - 0041-008X, 0041-008X KW - Carcinogens KW - 0 KW - Poisons KW - Tubulin KW - Superoxide Dismutase KW - EC 1.15.1.1 KW - Glutathione KW - GAN16C9B8O KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Chromosome Aberrations -- drug effects KW - Animals KW - Humans KW - Glutathione -- metabolism KW - Point Mutation KW - Superoxide Dismutase -- metabolism KW - Tubulin -- biosynthesis KW - Cell Cycle -- drug effects KW - Arsenic -- toxicity KW - Poisons -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68153752?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Insights+into+the+carcinogenic+mode+of+action+of+arsenic.&rft.au=Kligerman%2C+A+D%3BTennant%2C+A+H&rft.aulast=Kligerman&rft.aufirst=A&rft.date=2007-08-01&rft.volume=222&rft.issue=3&rft.spage=281&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2007-09-28 N1 - Date created - 2007-08-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Development of an Environmental Relative Moldiness index for US homes. AN - 68153219; 17693779 AB - The objective of this study was to establish a national relative moldiness index for homes in the United States. As part of the Housing and Urban Development's American Healthy Homes Survey, dust samples were collected by vacuuming 2 m in the bedrooms plus 2 m in the living rooms from a nationally representative 1096 homes in the United States using the Mitest sampler. Five milligrams of sieved (300 mum pore, nylon mesh) dust was analyzed by mold-specific quantitative polymerase chain reaction for the 36 indicator species in 1096 samples. On the basis of this standardized national sampling and analysis, an "Environmental Relative Moldiness Index" was created with values ranging from about -10 to 20 or above (lowest to highest). The Environmental Relative Moldiness Index scale may be useful for home mold-burden estimates in epidemiological studies. JF - Journal of occupational and environmental medicine AU - Vesper, Stephen AU - McKinstry, Craig AU - Haugland, Richard AU - Wymer, Larry AU - Bradham, Karen AU - Ashley, Peter AU - Cox, David AU - Dewalt, Gary AU - Friedman, Warren AD - United States Environmental Protection Agency, National Exposure Research Laboratory, Cincinnati, Ohio 45268, USA. vesper.stephen@epa.gov Y1 - 2007/08// PY - 2007 DA - August 2007 SP - 829 EP - 833 VL - 49 IS - 8 KW - Dust KW - 0 KW - Index Medicus KW - Polymerase Chain Reaction KW - Housing KW - Humans KW - Colony Count, Microbial KW - Fungi -- classification KW - Air Pollution, Indoor -- analysis KW - Dust -- analysis KW - Environmental Exposure -- analysis KW - Fungi -- isolation & purification KW - Air Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/68153219?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+occupational+and+environmental+medicine&rft.atitle=Development+of+an+Environmental+Relative+Moldiness+index+for+US+homes.&rft.au=Vesper%2C+Stephen%3BMcKinstry%2C+Craig%3BHaugland%2C+Richard%3BWymer%2C+Larry%3BBradham%2C+Karen%3BAshley%2C+Peter%3BCox%2C+David%3BDewalt%2C+Gary%3BFriedman%2C+Warren&rft.aulast=Vesper&rft.aufirst=Stephen&rft.date=2007-08-01&rft.volume=49&rft.issue=8&rft.spage=829&rft.isbn=&rft.btitle=&rft.title=Journal+of+occupational+and+environmental+medicine&rft.issn=1536-5948&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2008-03-12 N1 - Date created - 2007-08-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Sudden oak death: geographic risk estimates and predictions of origins AN - 20504403; 8003779 AB - Ecological niche modelling techniques were applied to address the questions of the origins and potential geographic extent of sudden oak death, caused by the pathogen Phytophthora ramorum. Based on an ecological niche model derived from the phytopathogen's California distribution and distributions of potential host species, it was determined that the disease has high potential to colonize the southeastern United States, and that its likely source area is eastern Asia. JF - Plant Pathology AU - Kluza, DA AU - Vieglais, DA AU - Andreasen, J K AU - Peterson, A T AD - U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, 8623-N, 1200 Pennsylvania Avenue Northwest, Washington, DC 20460; and, daniel.kluza@maf.govt.nz Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 580 EP - 587 PB - Blackwell Publishing Ltd., 9600 Garsington Road VL - 56 IS - 4 SN - 0032-0862, 0032-0862 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - ecological niche model KW - genetic algorithm for rule-set prediction KW - Phytophthora ramorum KW - sudden oak death KW - Niches KW - Phytophthora KW - Pathogens KW - A 01360:Plant Diseases KW - K 03420:Plant Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20504403?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Plant+Pathology&rft.atitle=Sudden+oak+death%3A+geographic+risk+estimates+and+predictions+of+origins&rft.au=Kluza%2C+DA%3BVieglais%2C+DA%3BAndreasen%2C+J+K%3BPeterson%2C+A+T&rft.aulast=Kluza&rft.aufirst=DA&rft.date=2007-08-01&rft.volume=56&rft.issue=4&rft.spage=580&rft.isbn=&rft.btitle=&rft.title=Plant+Pathology&rft.issn=00320862&rft_id=info:doi/10.1111%2Fj.1365-3059.2007.01602.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2008-02-01 N1 - Last updated - 2015-03-27 N1 - SubjectsTermNotLitGenreText - Niches; Pathogens; Phytophthora DO - http://dx.doi.org/10.1111/j.1365-3059.2007.01602.x ER - TY - JOUR T1 - Quo vadis source tracking? Towards a strategic framework for environmental monitoring of fecal pollution AN - 20483420; 7552437 AB - Advances in microbial source tracking (MST) have largely been driven by the need to comply with water quality standards based on traditional indicator bacteria. Recently, a number of culture-independent, and library-independent methods based on polymerase chain reaction (PCR) have been gaining popularity among source trackers. However, only a limited number of these methods have been successfully used in field applications, primarily due to the fact that many of them are still being developed. In this critical outlook, we examine different viewpoints associated with the practical use of MST to identify critical research gaps, propose a priority-based timeline to address them, and outline emerging technologies that will likely impact the future of source tracking. We propose that it is necessary to consider each of these aspects in order to advance towards a unifying framework in source identification, so that fecal pollution monitoring can be reliably used for comprehensive environmental microbial monitoring, to develop risk assessment models, and to implement and validate adequate management practices. JF - Water Research AU - Santo Domingo, JW AU - Bambic, D G AU - Edge, T A AU - Wuertz, S AD - NRMRL/WSWRD/MCCB, 26 W. Martin Luther King Dr., MS 387, Cincinnati, OH 45268, USA, santodomingo.jorge@epa.gov Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 3539 EP - 3552 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 41 IS - 16 SN - 0043-1354, 0043-1354 KW - Pollution Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Aqualine Abstracts; Water Resources Abstracts KW - Assessments KW - Fecal coliforms KW - Polymerase chain reaction KW - Monitoring KW - P 2000:FRESHWATER POLLUTION KW - A 01450:Environmental Pollution & Waste Treatment KW - SW 3020:Sources and fate of pollution KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20483420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Research&rft.atitle=Quo+vadis+source+tracking%3F+Towards+a+strategic+framework+for+environmental+monitoring+of+fecal+pollution&rft.au=Santo+Domingo%2C+JW%3BBambic%2C+D+G%3BEdge%2C+T+A%3BWuertz%2C+S&rft.aulast=Santo+Domingo&rft.aufirst=JW&rft.date=2007-08-01&rft.volume=41&rft.issue=16&rft.spage=3539&rft.isbn=&rft.btitle=&rft.title=Water+Research&rft.issn=00431354&rft_id=info:doi/10.1016%2Fj.watres.2007.06.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Fecal coliforms; Monitoring DO - http://dx.doi.org/10.1016/j.watres.2007.06.001 ER - TY - JOUR T1 - Identification of chicken-specific fecal microbial sequences using a metagenomic approach AN - 20482534; 7552439 AB - In this study, we applied a genome fragment enrichment (GFE) method to select for genomic regions that differ among different fecal metagenomes. Competitive DNA hybridizations were performed between chicken fecal DNA and pig fecal DNA (CP) and between chicken fecal DNA and an avian DNA composite consisting of turkey, goose, and seagull fecal DNA extracts (CB) to enrich for chicken-specific DNA fragments. A total of 471 non-redundant chicken metagenomic sequences were retrieved and analyzed. All of the clone sequences were similar to prokaryotic genes, of which more than 60% could not be assigned to previously characterized functional roles. In general terms, sequences assigned characterized functional roles were associated with cellular processes (11.7%), metabolism (11.0%) and information storage and processing (13.4%). Approximately 53% of the non-redundant sequences are similar to genes present in intestinal bacteria belonging to Clostridia (20.9%), Bacteroidetes (15.0%), and Bacilli (17.3%). Twenty-five sequences from the CP and CB clone libraries were selected to develop chicken fecal-specific PCR assays. These assays were challenged against fecal DNA extracted from 21 different animal species, including mammals and birds. The results from the host-specificity studies showed that 12 of the assays had a high degree of specificity to chicken feces. In addition, three assays were specific to chicken and turkey while another four assays tested positive to more than two avian species, suggesting a broader distribution of some of the enriched gene fragments among different avian fecal microbial communities. Fecal pollution signals were detected using chicken-specific assays in contaminated water samples, although the PCR assays showed different detection limits. These results indicate the need for multiple assays to detect poultry fecal sources of pollution. The competitive DNA hybridization approach used in this study can rapidly select for numerous chicken fecal metagenomic regions that can be used as potential genetic markers for fecal source tracking. JF - Water Research AU - Lu, J AU - Santo Domingo, J AU - Shanks, O C AD - Office of Research and Development, National Risk Management Research Laboratory, 26 West Martin Luther King Drive, MS-387, Cincinnati, OH, USA, santodomingo.jorge@epa.gov Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 3561 EP - 3574 PB - Elsevier Science Ltd., The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 41 IS - 16 SN - 0043-1354, 0043-1354 KW - Genetics Abstracts; Pollution Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Aqualine Abstracts; Water Resources Abstracts KW - Analytical Methods KW - Assay KW - DNA KW - Turkey KW - Pollution KW - P 2000:FRESHWATER POLLUTION KW - SW 3010:Identification of pollutants KW - A 01330:Food Microbiology KW - AQ 00002:Water Quality KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20482534?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Research&rft.atitle=Identification+of+chicken-specific+fecal+microbial+sequences+using+a+metagenomic+approach&rft.au=Lu%2C+J%3BSanto+Domingo%2C+J%3BShanks%2C+O+C&rft.aulast=Lu&rft.aufirst=J&rft.date=2007-08-01&rft.volume=41&rft.issue=16&rft.spage=3561&rft.isbn=&rft.btitle=&rft.title=Water+Research&rft.issn=00431354&rft_id=info:doi/10.1016%2Fj.watres.2007.05.033 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-12-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Pollution; DNA; Assay; Turkey DO - http://dx.doi.org/10.1016/j.watres.2007.05.033 ER - TY - JOUR T1 - Research approaches to address uncertainties in the risk assessment of arsenic in drinking water AN - 19746709; 7546814 AB - Inorganic arsenic (iAs), an environmental drinking water contaminant, is a human toxicant and carcinogen. The public health community has developed recommendations and regulations that limit human exposure to iAs in drinking water. Although there is a vast amount of information available to regulators on the exposure, disposition and the health-related effects of iAs, there is still critical information about the toxicology of this metalloid that is needed. This necessary information includes identification of the chemical species of arsenic that is (are) the active toxicant(s), the mode(s) of action for its various toxicities and information on potentially susceptible populations. Because of these unknown factors, the risk assessment of iAs still incorporates default assumptions, leading to uncertainties in the overall assessment. The characteristics of a scientifically defensible risk assessment for iAs are that it must: (1) quantitatively link exposure and target tissue dose of active metabolites to key events in the mode of action for major health effects and (2) identify sources of variation in susceptibility to arsenic-induced health effects and quantitatively evaluate their impact wherever possible. Integration of research to address these goals will better protect the health of iAs-exposed populations. JF - Toxicology and Applied Pharmacology AU - Hughes, M F AU - Kenyon, E M AU - Kitchin, K T AD - Office of Research and Development, National Health and Environmental Effects Research Laboratory, MD B143-01, Research Triangle Park, NC 27711, USA, hughes.michaelf@epa.gov Y1 - 2007/08/01/ PY - 2007 DA - 2007 Aug 01 SP - 399 EP - 404 PB - Elsevier Science B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 222 IS - 3 SN - 0041-008X, 0041-008X KW - Pollution Abstracts; Toxicology Abstracts KW - Risk assessment KW - Arsenic KW - Toxicants KW - Metabolites KW - Disposition KW - Toxicity KW - Carcinogens KW - Public health KW - Integration KW - Chemical speciation KW - Drinking water KW - Contaminants KW - Toxicology KW - P 2000:FRESHWATER POLLUTION KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19746709?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Research+approaches+to+address+uncertainties+in+the+risk+assessment+of+arsenic+in+drinking+water&rft.au=Hughes%2C+M+F%3BKenyon%2C+E+M%3BKitchin%2C+K+T&rft.aulast=Hughes&rft.aufirst=M&rft.date=2007-08-01&rft.volume=222&rft.issue=3&rft.spage=399&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2007.01.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-09-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Integration; Arsenic; Toxicants; Disposition; Metabolites; Carcinogens; Toxicity; Contaminants; Drinking water; Public health; Chemical speciation; Toxicology DO - http://dx.doi.org/10.1016/j.taap.2007.01.021 ER - TY - JOUR T1 - Effects of bromodichloromethane on ex vivo and in vitro luteal function and bromodichloromethane tissue dosimetry in the pregnant F344 rat AN - 19706812; 7497238 AB - Bromodichloromethane (BDCM), a drinking water disinfection by-product, causes pregnancy loss, i.e. full-litter resorption, in F344 rats when treated during the luteinizing hormone (LH)-dependent period. This effect is associated with reduced maternal serum progesterone (P) and LH levels, suggesting that BDCM disrupts secretion of LH. To test the hypothesis that BDCM also affects luteal responsiveness to LH, we used ex vivo and in vitro approaches. For the ex vivo study (i.e., in vivo exposure followed by in vitro assessment), dams were dosed by gavage on gestation days (GD) 6-9 (plug day=GD 0) at 0 or 100mg/kg/d. One hour after the GD-9 dose, rats were killed, blood was collected, and tissue concentrations of BDCM were assessed. Corpora lutea (CL) were incubated with or without hCG, an LH agonist, to stimulate P secretion. For the in vitro study, CL were pooled from untreated F344 rats on GD 9 and cultured with BDCM at 0, 0.01, 0.10 or 3.0mM. BDCM was found at highest concentrations in adrenal, ovarian, adipose, and hypothalamic tissues. BDCM treatment decreased serum P and LH levels in vivo. Ex vivo, however, BDCM-exposed CL showed >2-fold increases in P secretion relative to controls. Both control and BDCM-exposed CL displayed a 2.4-fold increase in P secretion in response to hCG challenge. In contrast, in vitro exposures reduced CL responsiveness in a dose-related fashion while baseline levels were unaffected. It is unclear if the ex vivo 'rebound' reflects the removal of the CL from a possible direct inhibitory influence of BDCM, or a response to diminished LH stimulation in vivo. Thus, these data suggest that BDCM disrupts pregnancy in F344 rats via two modes: disruption of LH secretion, and disruption of the CL's ability to respond to LH. JF - Toxicology In Vitro AU - Bielmeier AU - Murr, A S AU - Best, D S AU - Harrison, R A AU - Pegram, R A AU - Goldman, J M AU - Narotsky, M G AD - National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, United States, narotsky.michael@epa.gov Y1 - 2007/08// PY - 2007 DA - Aug 2007 SP - 919 EP - 928 PB - Elsevier Science Ltd., Pergamon, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 21 IS - 5 SN - 0887-2333, 0887-2333 KW - Toxicology Abstracts KW - Disinfection KW - Hypothalamus KW - Progesterone KW - Secretion KW - Abortion KW - Dosimetry KW - Bromodichloromethane KW - Pregnancy KW - Blood KW - Luteinizing hormone KW - Gestation KW - Drinking water KW - X 24340:Cosmetics, Toiletries & Household Products UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/19706812?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+In+Vitro&rft.atitle=Effects+of+bromodichloromethane+on+ex+vivo+and+in+vitro+luteal+function+and+bromodichloromethane+tissue+dosimetry+in+the+pregnant+F344+rat&rft.au=Bielmeier%3BMurr%2C+A+S%3BBest%2C+D+S%3BHarrison%2C+R+A%3BPegram%2C+R+A%3BGoldman%2C+J+M%3BNarotsky%2C+M+G&rft.aulast=Bielmeier&rft.aufirst=&rft.date=2007-08-01&rft.volume=21&rft.issue=5&rft.spage=919&rft.isbn=&rft.btitle=&rft.title=Toxicology+In+Vitro&rft.issn=08872333&rft_id=info:doi/10.1016%2Fj.tiv.2007.01.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2007-07-01 N1 - Last updated - 2015-04-01 N1 - SubjectsTermNotLitGenreText - Disinfection; Blood; Hypothalamus; Progesterone; Abortion; Luteinizing hormone; Secretion; Dosimetry; Gestation; Drinking water; Bromodichloromethane; Pregnancy DO - http://dx.doi.org/10.1016/j.tiv.2007.01.017 ER -