TY - CPAPER T1 - Seafood toxins: Outbreaks, research, and management AN - 42292447; 3186493 AU - Hall, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 7500:Pharmacology KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42292447?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Seafood+toxins%3A+Outbreaks%2C+research%2C+and+management&rft.au=Hall%2C+S&rft.aulast=Hall&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: USAMRID, Toxinology Division, Fort Detrick, MD 21702, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analytical measurements of ciguatoxin levels in fish tissue using mass spectrometry AN - 42290353; 3186490 AU - Musser, S M AU - Granade, H R AU - Dickey, R W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 7500:Pharmacology KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42290353?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Analytical+measurements+of+ciguatoxin+levels+in+fish+tissue+using+mass+spectrometry&rft.au=Musser%2C+S+M%3BGranade%2C+H+R%3BDickey%2C+R+W&rft.aulast=Musser&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: USAMRID, Toxinology Division, Fort Detrick, MD 21702, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - New U.S. GMP - Implementation procedures AN - 42267257; 3169282 AU - Trautman, KA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42267257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=New+U.S.+GMP+-+Implementation+procedures&rft.au=Trautman%2C+KA&rft.aulast=Trautman&rft.aufirst=KA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Association for the Advancement of Medical Instrumentation, 3330 Washington Blvd., Suite 400, Arlington, VA 22201, Abstracts available. Price $25. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - IEC 601-1-2: Advantages, disadvantages, and future amendments AN - 42263262; 3169402 AU - Silberberg, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42263262?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=IEC+601-1-2%3A+Advantages%2C+disadvantages%2C+and+future+amendments&rft.au=Silberberg%2C+J&rft.aulast=Silberberg&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Association for the Advancement of Medical Instrumentation, 3330 Washington Blvd., Suite 400, Arlington, VA 22201, Abstracts available. Price $25. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Health benefits of Asian vegetarian foods AN - 42262971; 3172657 AU - Ang, CYW AU - Hang, Y D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42262971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Health+benefits+of+Asian+vegetarian+foods&rft.au=Ang%2C+CYW%3BHang%2C+Y+D&rft.aulast=Ang&rft.aufirst=CYW&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Institute of Food Technologists, Customer Service Dept., 221 N. LaSalle, Suite #300, Chicago, IL 60601, Abstracts available. Price $25 in U.S. and Canada; $50 elsewhere. Paper No. 71-3 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Microbiological concerns about modified atmosphere packaged (MAP) produce AN - 42256932; 3172820 AU - Rhodehamel, E J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42256932?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Microbiological+concerns+about+modified+atmosphere+packaged+%28MAP%29+produce&rft.au=Rhodehamel%2C+E+J&rft.aulast=Rhodehamel&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Institute of Food Technologists, Customer Service Dept., 221 N. LaSalle, Suite #300, Chicago, IL 60601, Abstracts available. Price $25 in U.S. and Canada; $50 elsewhere. Paper No. 83-6 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Immunophenotyping of normal human worker volunteers: Distribution and range studies AN - 42243432; 3142828 AU - Biagini, R E AU - Pinkerton, LE AU - Johanning, E AU - Hull, R D AU - Ward, E M AU - Luster, MI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42243432?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Immunophenotyping+of+normal+human+worker+volunteers%3A+Distribution+and+range+studies&rft.au=Biagini%2C+R+E%3BPinkerton%2C+LE%3BJohanning%2C+E%3BHull%2C+R+D%3BWard%2C+E+M%3BLuster%2C+MI&rft.aulast=Biagini&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332. Phone: (703)438-3115; Fax: (703)438-3113; Email 73162.506ompuserve, Abstracts available. Price $38. Poster Paper No. 1209 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In vitro cytotoxicity of fiberglass samples: Importance of physical properties AN - 42235162; 3141852 AU - Castranova, V AU - Pailes, W H AU - Judy, D J AU - Schwegler-Berry, D AU - Jones, W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42235162?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=In+vitro+cytotoxicity+of+fiberglass+samples%3A+Importance+of+physical+properties&rft.au=Castranova%2C+V%3BPailes%2C+W+H%3BJudy%2C+D+J%3BSchwegler-Berry%2C+D%3BJones%2C+W&rft.aulast=Castranova&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332. Phone: (703)438-3115; Fax: (703)438-3113; Email 73162.506ompuserve, Abstracts available. Price $38. Paper No. 246 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Biologically-based, quantitative risk assessment of neurotoxicants: Introduction AN - 42235122; 3141839 AU - Slikker, W Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42235122?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Biologically-based%2C+quantitative+risk+assessment+of+neurotoxicants%3A+Introduction&rft.au=Slikker%2C+W+Jr&rft.aulast=Slikker&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332. Phone: (703)438-3115; Fax: (703)438-3113; Email 73162.506ompuserve, Abstracts available. Price $38. Paper No. 233 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of antimony on mitochondrial function and protein thiol and adenine nucleotide status in cultured cardiac myocytes AN - 42231536; 3143270 AU - Tirmenstein, MA AU - Wey, HE AU - Mathias, P I AU - Toraason, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42231536?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+antimony+on+mitochondrial+function+and+protein+thiol+and+adenine+nucleotide+status+in+cultured+cardiac+myocytes&rft.au=Tirmenstein%2C+MA%3BWey%2C+HE%3BMathias%2C+P+I%3BToraason%2C+M&rft.aulast=Tirmenstein&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332. Phone: (703)438-3115; Fax: (703)438-3113; Email 73162.506ompuserve, Abstracts available. Price $38. Poster Paper No. 1662 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of calcium and phospholipase in potassium antimonyl tartrate-induced cardiac myocyte toxicity AN - 42231489; 3143269 AU - Wey, H AU - Richards, D AU - Mathias, P AU - Tirmenstein, M AU - Walker, C AU - Toraason, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42231489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+calcium+and+phospholipase+in+potassium+antimonyl+tartrate-induced+cardiac+myocyte+toxicity&rft.au=Wey%2C+H%3BRichards%2C+D%3BMathias%2C+P%3BTirmenstein%2C+M%3BWalker%2C+C%3BToraason%2C+M&rft.aulast=Wey&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332. Phone: (703)438-3115; Fax: (703)438-3113; Email 73162.506ompuserve, Abstracts available. Price $38. Poster Paper No. 1661 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tissue specific induction of hsp72 in heat treated rat embryos AN - 42228300; 3141879 AU - Fisher, B R AU - Brown, K M AU - Goering, P L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42228300?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Tissue+specific+induction+of+hsp72+in+heat+treated+rat+embryos&rft.au=Fisher%2C+B+R%3BBrown%2C+K+M%3BGoering%2C+P+L&rft.aulast=Fisher&rft.aufirst=B&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332. Phone: (703)438-3115; Fax: (703)438-3113; Email 73162.506ompuserve, Abstracts available. Price $38. Poster Paper No. 273 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Investigation of hepatoprotection afforded by repeated exposure to acetaminophen AN - 42228182; 3142428 AU - Roberts, D W AU - Shayiq, R AU - Snawder, JE AU - Benson, R W AU - Ho, L L AU - Ma, X AU - Black, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42228182?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Investigation+of+hepatoprotection+afforded+by+repeated+exposure+to+acetaminophen&rft.au=Roberts%2C+D+W%3BShayiq%2C+R%3BSnawder%2C+JE%3BBenson%2C+R+W%3BHo%2C+L+L%3BMa%2C+X%3BBlack%2C+M&rft.aulast=Roberts&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332. Phone: (703)438-3115; Fax: (703)438-3113; Email 73162.506ompuserve, Abstracts available. Price $38. Poster Paper No. 805 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - FDA software challenge AN - 42224799; 3143873 AU - Rudolph, H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42224799?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=FDA+software+challenge&rft.au=Rudolph%2C+H&rft.aulast=Rudolph&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Association for the Advancement of Science, Customer Service, 1333 H St., NW, Washington, DC 20005. Phone: (202)326-6450, Abstracts available. Price $25. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Toxicology testing for tumor promotion AN - 42218013; 3152281 AU - Grieshaber, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42218013?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Toxicology+testing+for+tumor+promotion&rft.au=Grieshaber%2C+C&rft.aulast=Grieshaber&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Phone: (610)825-3838; Fax: (610)834-8652, Selected Abstracts available. Price $8. Audio cassette available from The Hour Recording Co., PO Box 1299, St. Petersburg, FL 33731. Price $10. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sample size and population pharmacokinetic studies AN - 42217904; 3152241 AU - Ette, E I AU - Sun, H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42217904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Sample+size+and+population+pharmacokinetic+studies&rft.au=Ette%2C+E+I%3BSun%2C+H&rft.aulast=Ette&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Phone: (610)825-3838; Fax: (610)834-8652, Selected Abstracts available. Price $8. Audio cassette available from The Hour Recording Co., PO Box 1299, St. Petersburg, FL 33731. Price $10. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Proposed descriptors for muscle relaxant onset and duration AN - 42217464; 3152293 AU - Bedford, R AU - Spyker, D AU - Wright, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42217464?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Proposed+descriptors+for+muscle+relaxant+onset+and+duration&rft.au=Bedford%2C+R%3BSpyker%2C+D%3BWright%2C+C&rft.aulast=Bedford&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Phone: (610)825-3838; Fax: (610)834-8652, Selected Abstracts available. Price $8. Audio cassette available from The Hour Recording Co., PO Box 1299, St. Petersburg, FL 33731. Price $10. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Medical school teaching sites at public health agencies AN - 42216141; 3144974 AU - Melville, S K AU - Coghlin, J AU - Chen, D W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42216141?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Localization+of+the+Coeur+d%27Alene+mining+district+at+the+juncture+of+the+Lewis+and+Clark+and+Noxon+lines&rft.au=White%2C+Brian+G%3BAppelgate%2C+Larry+M%3BAnonymous&rft.aulast=White&rft.aufirst=Brian&rft.date=2000-03-01&rft.volume=32&rft.issue=5&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Association of Preventive Medicine, 1660 L Street, NW, Suite 206, Washington, DC 20036, Abstracts available. Price $5. Poster Paper No. PS37 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparable drug efficacy AN - 42215333; 3152289 AU - Stein, R A AU - Leung, H M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42215333?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparable+drug+efficacy&rft.au=Stein%2C+R+A%3BLeung%2C+H+M&rft.aulast=Stein&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Phone: (610)825-3838; Fax: (610)834-8652, Selected Abstracts available. Price $8. Audio cassette available from The Hour Recording Co., PO Box 1299, St. Petersburg, FL 33731. Price $10. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Women and special populations in Phase 1 research: FDA perspective AN - 42215313; 3152272 AU - Williams, R L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42215313?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=New+strategies+for+the+evaluation+of+the+carcinogenic+activities+of+chemicals&rft.au=Schwetz%2C+BA&rft.aulast=Schwetz&rft.aufirst=BA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Phone: (610)825-3838; Fax: (610)834-8652, Selected Abstracts available. Price $8. Audio cassette available from The Hour Recording Co., PO Box 1299, St. Petersburg, FL 33731. Price $10. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Prenatal ultrasound and birth weight: Does the timing of first exposure affect outcome? AN - 42198764; 3135568 AU - Marinac-Dabic, D AU - Krulewitch, C J AU - Moore, RM Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42198764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Prenatal+ultrasound+and+birth+weight%3A+Does+the+timing+of+first+exposure+affect+outcome%3F&rft.au=Marinac-Dabic%2C+D%3BKrulewitch%2C+C+J%3BMoore%2C+RM+Jr&rft.aulast=Marinac-Dabic&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Public Health Association, Publication Sales, 1015 15th St., NW, Washington, DC 20005, USA, Abstracts available. Price $30 for 2-volume set. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of natural killer cells in the rauscher murine leukemia virus model: Immunomodulatory and antiviral mechanisms of 9-(2-phosphonyl-methoxyethyl)adenine AN - 42187058; 3122829 AU - Kunder, S C AU - Black, P L AU - Hall, B E AU - Ussery, MA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42187058?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+natural+killer+cells+in+the+rauscher+murine+leukemia+virus+model%3A+Immunomodulatory+and+antiviral+mechanisms+of+9-%282-phosphonyl-methoxyethyl%29adenine&rft.au=Kunder%2C+S+C%3BBlack%2C+P+L%3BHall%2C+B+E%3BUssery%2C+MA&rft.aulast=Kunder&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Books International, PO Box 605, Herndon, VA 22070, Abstracts available. Price $25. Poster Paper No. I140 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Human peripheral blood mononuclear cells labeled with the fluorescent dye PKH26 can replicate HIV-1 in vitro and in vivo in HuPBMC-SCID mice AN - 42185073; 3122828 AU - Wood, O L AU - Black, P L AU - Broud, D D AU - Ussery, MA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42185073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Human+peripheral+blood+mononuclear+cells+labeled+with+the+fluorescent+dye+PKH26+can+replicate+HIV-1+in+vitro+and+in+vivo+in+HuPBMC-SCID+mice&rft.au=Wood%2C+O+L%3BBlack%2C+P+L%3BBroud%2C+D+D%3BUssery%2C+MA&rft.aulast=Wood&rft.aufirst=O&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Books International, PO Box 605, Herndon, VA 22070, Abstracts available. Price $25. Poster Paper No. I138 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Passive immunization of mice with antiserum to capsular polysaccharide-tetanus toxoid conjugate confers protection against Vibrio vulnificus septicemia AN - 42181837; 3123186 AU - Devi, S AU - Hayat, U AU - Powell, J AU - Frasch, CE AU - Morris, JG Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42181837?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Passive+immunization+of+mice+with+antiserum+to+capsular+polysaccharide-tetanus+toxoid+conjugate+confers+protection+against+Vibrio+vulnificus+septicemia&rft.au=Devi%2C+S%3BHayat%2C+U%3BPowell%2C+J%3BFrasch%2C+CE%3BMorris%2C+JG+Jr&rft.aulast=Devi&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Books International, PO Box 605, Herndon, VA 22070, Abstracts available. Price $25. Poster Paper No. G82 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Food facility plan review AN - 42031311; 3116831 AU - Schrade, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42031311?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Food+facility+plan+review&rft.au=Schrade%2C+J&rft.aulast=Schrade&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: International Association of Milk, Food and Environmental Sanitarians, 6200 Aurora Ave., Suite 200W, Des Moines, IA 50322, USA., Abstracts available. Price $10.50. Paper No. 16 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Biotransformations of polyaromatic hydrocarbons AN - 42029568; 3102210 AU - Cerniglia, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42029568?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Biotransformations+of+polyaromatic+hydrocarbons&rft.au=Cerniglia%2C+C&rft.aulast=Cerniglia&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - International food safety and quality standards AN - 42028105; 3117017 AU - Carnevale, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42028105?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=International+food+safety+and+quality+standards&rft.au=Carnevale%2C+C&rft.aulast=Carnevale&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: International Association of Milk, Food and Environmental Sanitarians, 6200 Aurora Ave., Suite 200W, Des Moines, IA 50322, USA., Abstracts available. Price $10.50. Paper No. 202 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Economics of federal HACCP regulations AN - 42027409; 3116911 AU - Zorn, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42027409?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Economics+of+federal+HACCP+regulations&rft.au=Zorn%2C+D&rft.aulast=Zorn&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: International Association of Milk, Food and Environmental Sanitarians, 6200 Aurora Ave., Suite 200W, Des Moines, IA 50322, USA., Abstracts available. Price $10.50. Poster Paper No. 96 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Regulatory perspectives on the use of bacteriocins in foods AN - 42027114; 3116988 AU - Fields, F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42027114?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Regulatory+perspectives+on+the+use+of+bacteriocins+in+foods&rft.au=Fields%2C+F&rft.aulast=Fields&rft.aufirst=F&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: International Association of Milk, Food and Environmental Sanitarians, 6200 Aurora Ave., Suite 200W, Des Moines, IA 50322, USA., Abstracts available. Price $10.50. Paper No. 173 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Long-term survival of Vibrio cholerae O1 in seawater AN - 42026812; 3104466 AU - McCarthy, SA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42026812?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Co-amplification+of+specific+sequences+of+HIV-1+and+HCV+genomes+by+the+polymerase+chain+reaction+assay%3A+A+potential+tool+for+the+simultaneous+detection+of+HIV-1+and+HCV&rft.au=Nedjar%2C+S%3BHewlett%2C+I%3BBiswas%2C+R&rft.aulast=Nedjar&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. Q480 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Intranasal administration of filamentous hemagglutinin liposomes stimulates protective immunity against Bordetella pertussis infection AN - 42024068; 3101782 AU - Leef, M AU - Schwartz, GM Jr AU - Alving, C R AU - Shahin, R D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42024068?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Intranasal+administration+of+filamentous+hemagglutinin+liposomes+stimulates+protective+immunity+against+Bordetella+pertussis+infection&rft.au=Leef%2C+M%3BSchwartz%2C+GM+Jr%3BAlving%2C+C+R%3BShahin%2C+R+D&rft.aulast=Leef&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. E44 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Genomic restriction pattern diversity among Vibrio vulnificus from different environments AN - 42020236; 3103503 AU - Singer, P D AU - Tall, B D AU - Khambaty, F M AU - Shah, D B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42020236?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Genomic+restriction+pattern+diversity+among+Vibrio+vulnificus+from+different+environments&rft.au=Singer%2C+P+D%3BTall%2C+B+D%3BKhambaty%2C+F+M%3BShah%2C+D+B&rft.aulast=Singer&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. C417 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - katG gene of isoniazid-resistant strains of Mycobacterium tuberculosis AN - 42017535; 3104074 AU - Rouse, D AU - Morris, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42017535?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=katG+gene+of+isoniazid-resistant+strains+of+Mycobacterium+tuberculosis&rft.au=Rouse%2C+D%3BMorris%2C+S&rft.aulast=Rouse&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. U125 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - N-Oxidation of isoquinoline by the fungus Cunninghamella elegans AN - 42015390; 3103939 AU - Sutherland, J B AU - Freeman, J P AU - Williams, A J AU - Cerniglia, CE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42015390?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=N-Oxidation+of+isoquinoline+by+the+fungus+Cunninghamella+elegans&rft.au=Sutherland%2C+J+B%3BFreeman%2C+J+P%3BWilliams%2C+A+J%3BCerniglia%2C+CE&rft.aulast=Sutherland&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. Q443 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Stress conditions affect virulence of a rifampin-resistant mutant of Francisella tularensis AN - 42014914; 3101383 AU - Bhatnagar, LVSN AU - Elkins, K AU - Fortier, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42014914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Stress+conditions+affect+virulence+of+a+rifampin-resistant+mutant+of+Francisella+tularensis&rft.au=Bhatnagar%2C+LVSN%3BElkins%2C+K%3BFortier%2C+A&rft.aulast=Bhatnagar&rft.aufirst=LVSN&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. D98 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Improved rapid technique for isolation of Escherichia coli O157:H7 from foods AN - 42011707; 3104284 AU - Weagant, S D AU - Bryant, J L AU - Jinneman, K G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42011707?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Improved+rapid+technique+for+isolation+of+Escherichia+coli+O157%3AH7+from+foods&rft.au=Weagant%2C+S+D%3BBryant%2C+J+L%3BJinneman%2C+K+G&rft.aulast=Weagant&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Paper No. P94 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of nasal corticoid treatments in hayfever studies AN - 42010101; 3083184 AU - Harter, J G AU - Stein, R A AU - Love, P Y Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42010101?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Analysis+of+nasal+corticoid+treatments+in+hayfever+studies&rft.au=Harter%2C+J+G%3BStein%2C+R+A%3BLove%2C+P+Y&rft.aulast=Harter&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacolgy and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800, USA. Poster Paper No. PII-17 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sulindac: Exploratory modeling and bioequivalence implications AN - 42009376; 3083117 AU - Hale, V G AU - Borga, O AU - Harter, J G AU - Katzper, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42009376?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Sulindac%3A+Exploratory+modeling+and+bioequivalence+implications&rft.au=Hale%2C+V+G%3BBorga%2C+O%3BHarter%2C+J+G%3BKatzper%2C+M&rft.aulast=Hale&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacolgy and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800, USA. Poster Paper No. PI-69 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of prolonged starvation on mutation spectra AN - 42008610; 3094021 AU - Prival, MJ AU - Cebula, T A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42008610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+prolonged+starvation+on+mutation+spectra&rft.au=Prival%2C+MJ%3BCebula%2C+T+A&rft.aulast=Prival&rft.aufirst=MJ&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, 605 Third Ave., New York, NY 10158-0012 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bias (B) and efficiency (EFF) effects of correlation (CORR) between pharmacokinetics (PK) and pharmacodynamics (PD) in post-hoc concentration-effect (CE) analyses of parallel dose-response trials AN - 42006668; 3083208 AU - Peck, C AU - Ludden, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42006668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Bias+%28B%29+and+efficiency+%28EFF%29+effects+of+correlation+%28CORR%29+between+pharmacokinetics+%28PK%29+and+pharmacodynamics+%28PD%29+in+post-hoc+concentration-effect+%28CE%29+analyses+of+parallel+dose-response+trials&rft.au=Peck%2C+C%3BLudden%2C+T&rft.aulast=Peck&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacolgy and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800, USA. Poster Paper No. PII-41 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Disposition of malachite green in the channel catfish AN - 42006253; 3087636 AU - Plakas, S M AU - El-Said, K R AU - Stehly, G R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42006253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Disposition+of+malachite+green+in+the+channel+catfish&rft.au=Plakas%2C+S+M%3BEl-Said%2C+K+R%3BStehly%2C+G+R&rft.aulast=Plakas&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332, USA, Price $38.. Paper No. 1710 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Detection of ciguatera toxin in fish using HPTLC techniques AN - 42005298; 3102072 AU - Dixon, L G AU - Hamdy, M K AU - Hayden, MA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42005298?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Detection+of+ciguatera+toxin+in+fish+using+HPTLC+techniques&rft.au=Dixon%2C+L+G%3BHamdy%2C+M+K%3BHayden%2C+MA&rft.aulast=Dixon&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. P29 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative effects of quinoline and 8-hydroxyquinoline on glutathione levels, DNA fragmentation and enzyme induction in cultured rat hepatocytes AN - 42004899; 3086630 AU - Tirmenstein, MA AU - Snawder, JE AU - Plews, P I AU - Torraason, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42004899?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparative+effects+of+quinoline+and+8-hydroxyquinoline+on+glutathione+levels%2C+DNA+fragmentation+and+enzyme+induction+in+cultured+rat+hepatocytes&rft.au=Tirmenstein%2C+MA%3BSnawder%2C+JE%3BPlews%2C+P+I%3BTorraason%2C+M&rft.aulast=Tirmenstein&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332, USA, Price $38.. Poster Paper No. 702 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Biofilm formation in water supply lines of dental air-water syringes AN - 42003282; 3102048 AU - Gray, R T AU - Kelley, JI AU - George, K S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42003282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Biofilm+formation+in+water+supply+lines+of+dental+air-water+syringes&rft.au=Gray%2C+R+T%3BKelley%2C+JI%3BGeorge%2C+K+S&rft.aulast=Gray&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. Poster Paper No. N39 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Secretion of pertussis toxin from Bordetella pertussis AN - 42003148; 3100468 AU - Burns, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42003148?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Secretion+of+pertussis+toxin+from+Bordetella+pertussis&rft.au=Burns%2C+D&rft.aulast=Burns&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Ave., NW, Washington, DC 20005, Abstracts. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative developmental toxicity of urethane (URE), 2-methoxyethanol (2ME) and methotrexate (MTX) in Drosophila melanogaster obtained from two sources AN - 42002475; 3086522 AU - Lynch, D W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42002475?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparative+developmental+toxicity+of+urethane+%28URE%29%2C+2-methoxyethanol+%282ME%29+and+methotrexate+%28MTX%29+in+Drosophila+melanogaster+obtained+from+two+sources&rft.au=Lynch%2C+D+W&rft.aulast=Lynch&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332, USA, Price $38.. Poster Paper No. 594 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mutational events at Salmonella typhimurium base-substitution alleles as predictors of eukaryotic mutational specificity AN - 42002367; 3093932 AU - Koch, W H AU - Cebula, T A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42002367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Mutational+events+at+Salmonella+typhimurium+base-substitution+alleles+as+predictors+of+eukaryotic+mutational+specificity&rft.au=Koch%2C+W+H%3BCebula%2C+T+A&rft.aulast=Koch&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, 605 Third Ave., New York, NY 10158-0012 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sequence changes induced by ENNG at the Ochre locus in E. coli WU3610 AN - 42002210; 3093865 AU - Elespuru, R K AU - Tada, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42002210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Sequence+changes+induced+by+ENNG+at+the+Ochre+locus+in+E.+coli+WU3610&rft.au=Elespuru%2C+R+K%3BTada%2C+M&rft.aulast=Elespuru&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, 605 Third Ave., New York, NY 10158-0012 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identification, characterization, and origins of an imp operon on F' episomes carrying finp301 AN - 42001515; 3093864 AU - Eisenstadt, E AU - Henrikson, E AU - Koch, W H AU - Cebula, T A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42001515?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Identification%2C+characterization%2C+and+origins+of+an+imp+operon+on+F%27+episomes+carrying+finp301&rft.au=Eisenstadt%2C+E%3BHenrikson%2C+E%3BKoch%2C+W+H%3BCebula%2C+T+A&rft.aulast=Eisenstadt&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, 605 Third Ave., New York, NY 10158-0012 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of titanium oxide (TiO) particles on tumor necrosis factor (TNFa) production, relative survival, and phagocytosis in cultured murine macrophages AN - 41994128; 3086826 AU - Goering, P L AU - Kish, CL AU - Kuester, R K AU - Hitchins, V M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41994128?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+titanium+oxide+%28TiO%29+particles+on+tumor+necrosis+factor+%28TNFa%29+production%2C+relative+survival%2C+and+phagocytosis+in+cultured+murine+macrophages&rft.au=Goering%2C+P+L%3BKish%2C+CL%3BKuester%2C+R+K%3BHitchins%2C+V+M&rft.aulast=Goering&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 22090-5332, USA, Price $38.. Poster Paper No. 900 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Surrogate markers in early clinical trials AN - 41965804; 3064417 AU - Feigal, D W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:MULTIDISCIPLINARY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41965804?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Surrogate+markers+in+early+clinical+trials&rft.au=Feigal%2C+D+W&rft.aulast=Feigal&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM PressP.O. Box 605 Herndon, VA 22070; ph: (703)787-3305, Program and Abstracts N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Research protocol for patient outcomes evaluation of geriatric physician faculty fellowships AN - 41961906; 3076553 AU - Cogliano, J F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41961906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Research+protocol+for+patient+outcomes+evaluation+of+geriatric+physician+faculty+fellowships&rft.au=Cogliano%2C+J+F&rft.aulast=Cogliano&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Gerontologist, 1275 K St., NW, Suite 350, Washington, DC 20005-4006, Selected abstracts. Price $10.. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Developmental defects induced by organophosphorus compounds in anuran embryos AN - 41953521; 3075117 AU - Snawder, JE AU - Fulton, M H AU - Chambers, JE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 5500:GEOSCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41953521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Developmental+defects+induced+by+organophosphorus+compounds+in+anuran+embryos&rft.au=Snawder%2C+JE%3BFulton%2C+M+H%3BChambers%2C+JE&rft.aulast=Snawder&rft.aufirst=JE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Environmenral Toxicology and Chemistry, 1010 North 12th Ave., Pensacola, FL 32501 Telephone:(904)469-1500, Abstracts. Price $30.. Paper No. 193 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Pharmacokinetics and metabolism of waterborne chlorpyrifos in channel catfish AN - 41950114; 3075679 AU - Plakas, S M AU - Barron, M G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 5500:GEOSCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41950114?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Pharmacokinetics+and+metabolism+of+waterborne+chlorpyrifos+in+channel+catfish&rft.au=Plakas%2C+S+M%3BBarron%2C+M+G&rft.aulast=Plakas&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Environmenral Toxicology and Chemistry, 1010 North 12th Ave., Pensacola, FL 32501 Telephone:(904)469-1500, Abstracts. Price $30.. Poster Paper No. P269 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gender differences in bone mineralization among rats fed flaxseed AN - 41923039; 3047141 AU - Kaup, S M AU - Hight, S C AU - Ahn, S M AU - Rader, JI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41923039?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Gender+differences+in+bone+mineralization+among+rats+fed+flaxseed&rft.au=Kaup%2C+S+M%3BHight%2C+S+C%3BAhn%2C+S+M%3BRader%2C+JI&rft.aulast=Kaup&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Mary Ann Liebert, Inc.1651 Third Avenue, New York, NY 10128, USA; Telephone: (212) 289-2300, Abstracts, Journal of Bone and Mineral Research, Volume 8 Supplement 1 August 1993, ISSN: 0884-0431 Poster Paper No. 635 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Rayleigh task performance in tomographic reconstructions: Comparison of human and machine performance AN - 41913995; 2977811 AU - Wagner, R F AU - Myers, K J AU - Hanson, K M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 4500:EXPERIMENTAL MEDICINE KW - U 8000:PHYSICS AND ASTRONOMY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41913995?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Rayleigh+task+performance+in+tomographic+reconstructions%3A+Comparison+of+human+and+machine+performance&rft.au=Wagner%2C+R+F%3BMyers%2C+K+J%3BHanson%2C+K+M&rft.aulast=Wagner&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: SPIE, PO Box 10, Bellingham, WA 98227-0010, USA; Phone: 206/676/3290; Fax: 206/647-1445; Internet: spieom.spie.org; Telex: 46-7053; OPTO-LINK: 206/733-2998, Proceedings Paper No. 1898-64 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Inflammatory response gene expression in rejecting MHC class II disparate grafts AN - 41899575; 3047970 AU - Henricson, B AU - Rosenberg, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41899575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Inflammatory+response+gene+expression+in+rejecting+MHC+class+II+disparate+grafts&rft.au=Henricson%2C+B%3BRosenberg%2C+A&rft.aulast=Henricson&rft.aufirst=B&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Association of Immunologists428 East Preston Street, Baltimore, MD 21202, USA, Abstracts, Journal of Immunology, ISSN: 002-1767, Volume 150/Number 8/Part II/April 15, 1993 Paper No. 299 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Recovery from midazolam sedation AN - 41891368; 2930402 AU - Wright, C AU - Spyker, D AU - Harter, J G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41891368?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Recovery+from+midazolam+sedation&rft.au=Wright%2C+C%3BSpyker%2C+D%3BHarter%2C+J+G&rft.aulast=Wright&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCPT, 1718 Gallagher Rd., Norristown, PA 19401-2800, USA; Telephone: (215) 825-3838; Fax: (215) 834-8652, Abstracts Poster Paper No. PIII-46 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of OTC drug usage studies AN - 41872887; 2930443 AU - Katz, L M AU - Stein, R A AU - Harter, J G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41872887?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Analysis+of+OTC+drug+usage+studies&rft.au=Katz%2C+L+M%3BStein%2C+R+A%3BHarter%2C+J+G&rft.aulast=Katz&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCPT, 1718 Gallagher Rd., Norristown, PA 19401-2800, USA; Telephone: (215) 825-3838; Fax: (215) 834-8652, Abstracts Poster Paper No. PIII-60 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling pain and its response to analgesics AN - 41870222; 2929742 AU - Harter, J AU - Katzper, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41870222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Modeling+pain+and+its+response+to+analgesics&rft.au=Harter%2C+J%3BKatzper%2C+M&rft.aulast=Harter&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCPT, 1718 Gallagher Rd., Norristown, PA 19401-2800, USA; Telephone: (215) 825-3838; Fax: (215) 834-8652, Abstracts Poster Paper No. PII-4 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Persistent HIV-1 (MN) infection of mammary epithelial cells in vitro AN - 41857093; 2935263 AU - Poffenberger, K L AU - Riordan, G AU - Lee, S AU - Epstein, J AU - Hewlett, I Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41857093?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Persistent+HIV-1+%28MN%29+infection+of+mammary+epithelial+cells+in+vitro&rft.au=Poffenberger%2C+K+L%3BRiordan%2C+G%3BLee%2C+S%3BEpstein%2C+J%3BHewlett%2C+I&rft.aulast=Poffenberger&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 605 Third Avenue, 9th Floor, New York, NY 10158-0012, USA; Telephone: (212) 850-6543, Abstracts, Journal of Cellular Biochemistry, Supplement 17E, 1993, ISSN: 0730-2312 Poster Paper No. Q242 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Influence of inter-animal variability on the estimation of population pharmacokinetic (PK) parameters in preclinical studies AN - 41855708; 2930375 AU - Ette, E AU - Kelman, A AU - Howie, C AU - Whiting, B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41855708?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Influence+of+inter-animal+variability+on+the+estimation+of+population+pharmacokinetic+%28PK%29+parameters+in+preclinical+studies&rft.au=Ette%2C+E%3BKelman%2C+A%3BHowie%2C+C%3BWhiting%2C+B&rft.aulast=Ette&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCPT, 1718 Gallagher Rd., Norristown, PA 19401-2800, USA; Telephone: (215) 825-3838; Fax: (215) 834-8652, Abstracts Poster Paper No. PIII-38 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mutagenicity of coal dust and smokeless tobacco extracts in Salmonella typhimurium strains with differing levels of O-acetyltransferase activities AN - 41854884; 2934149 AU - Stamm, S C AU - Zhong, B-Z AU - Whong, W-Z AU - Ong, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41854884?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Mutagenicity+of+coal+dust+and+smokeless+tobacco+extracts+in+Salmonella+typhimurium+strains+with+differing+levels+of+O-acetyltransferase+activities&rft.au=Stamm%2C+S+C%3BZhong%2C+B-Z%3BWhong%2C+W-Z%3BOng%2C+T&rft.aulast=Stamm&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 9th Floor, 605 Third Avenue, New York, NY 10158, USA; Telephone: (212) 850-6543, Abstracts, Environmental and Molecular Mutagenesis, Volume 21, Supplement 22, 1993, ISSN: 0893-6692 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Familial myositis cases emphasize the roles of genetic and environmental factors in the pathogenesis of idiopathic inflammatory myopathy (IIM) AN - 41853934; 2836359 AU - Gurley, R C AU - Targoff, IN AU - Garcia-de la Torre, AU - Hennekam, RCM AU - Kalovidouris, A E AU - Baumbach, L L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41853934?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Familial+myositis+cases+emphasize+the+roles+of+genetic+and+environmental+factors+in+the+pathogenesis+of+idiopathic+inflammatory+myopathy+%28IIM%29&rft.au=Gurley%2C+R+C%3BTargoff%2C+IN%3BGarcia-de+la+Torre%2C%3BHennekam%2C+RCM%3BKalovidouris%2C+A+E%3BBaumbach%2C+L+L&rft.aulast=Gurley&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ACR, Paper No. A123 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of cell transformation and oncogene activation by silica dust in BALB/C-3T3 cells AN - 41851343; 2933572 AU - Gao, H-G AU - Whong, W-Z AU - Cutler, D AU - Wallace, W E AU - Ong, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41851343?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction+of+cell+transformation+and+oncogene+activation+by+silica+dust+in+BALB%2FC-3T3+cells&rft.au=Gao%2C+H-G%3BWhong%2C+W-Z%3BCutler%2C+D%3BWallace%2C+W+E%3BOng%2C+T&rft.aulast=Gao&rft.aufirst=H-G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 9th Floor, 605 Third Avenue, New York, NY 10158, USA; Telephone: (212) 850-6543, Abstracts, Environmental and Molecular Mutagenesis, Volume 21, Supplement 22, 1993, ISSN: 0893-6692 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assessment of the pharmacokinetic/pharmacodynamic (PK/PD) performance of controlled release dosage forms (CRDF) involving partial AUCs AN - 41849285; 2929922 AU - Baweja, R AU - Longley, R AU - Johnson, S AU - Malinowski, HJ AU - Leonard, E M AU - Temple, R J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41849285?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Assessment+of+the+pharmacokinetic%2Fpharmacodynamic+%28PK%2FPD%29+performance+of+controlled+release+dosage+forms+%28CRDF%29+involving+partial+AUCs&rft.au=Baweja%2C+R%3BLongley%2C+R%3BJohnson%2C+S%3BMalinowski%2C+HJ%3BLeonard%2C+E+M%3BTemple%2C+R+J&rft.aulast=Baweja&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCPT, 1718 Gallagher Rd., Norristown, PA 19401-2800, USA; Telephone: (215) 825-3838; Fax: (215) 834-8652, Abstracts Poster Paper No. PII-63 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Demographic analysis of pharmacokinetics (PK) studies submitted for a new drug AN - 41847609; 2930337 AU - Hale, V G AU - Ludden, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41847609?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Demographic+analysis+of+pharmacokinetics+%28PK%29+studies+submitted+for+a+new+drug&rft.au=Hale%2C+V+G%3BLudden%2C+T&rft.aulast=Hale&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCPT, 1718 Gallagher Rd., Norristown, PA 19401-2800, USA; Telephone: (215) 825-3838; Fax: (215) 834-8652, Abstracts Poster Paper No. PIII-26 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - sIg mediated desensitization of PLC dependent pathways occurs at a point distal to tyrosine kinase (TK) activation AN - 41835157; 2903067 AU - Brunswick, M AU - June, C AU - Burkhardt, A AU - Bolen, J AU - Mond, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41835157?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=sIg+mediated+desensitization+of+PLC+dependent+pathways+occurs+at+a+point+distal+to+tyrosine+kinase+%28TK%29+activation&rft.au=Brunswick%2C+M%3BJune%2C+C%3BBurkhardt%2C+A%3BBolen%2C+J%3BMond%2C+J&rft.aulast=Brunswick&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 605 Third Avenue, 9th Floor, New York, NY 10158-0012, USA; Telephone: (212) 850-6543, Abstracts, Journal of Cellular Biochemistry, Supplement 17B 1993, ISSN: 0730-2312 Poster Paper No. FZ440 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of DNA adducts, micronuclei and sister chromatid exchanges by three industrial PAHs in the rat lung cell system AN - 41831518; 2935210 AU - Whong, W-Z AU - Stewart, J AU - Cutler, D AU - Ong, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41831518?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction+of+DNA+adducts%2C+micronuclei+and+sister+chromatid+exchanges+by+three+industrial+PAHs+in+the+rat+lung+cell+system&rft.au=Whong%2C+W-Z%3BStewart%2C+J%3BCutler%2C+D%3BOng%2C+T&rft.aulast=Whong&rft.aufirst=W-Z&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 9th Floor, 605 Third Avenue, New York, NY 10158, USA; Telephone: (212) 850-6543, Abstracts, Environmental and Molecular Mutagenesis, Volume 21, Supplement 22, 1993, ISSN: 0893-6692 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Associations among Gm phenotypes, HLA alleles, and myositis-specific autoantibodies (MSA) in idiopathic inflammatory myopathy (IIM) AN - 41822979; 2831572 AU - Enz, LA AU - Love, LA AU - Targoff, IN AU - Pandey, J P AU - Miller, F W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41822979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Associations+among+Gm+phenotypes%2C+HLA+alleles%2C+and+myositis-specific+autoantibodies+%28MSA%29+in+idiopathic+inflammatory+myopathy+%28IIM%29&rft.au=Enz%2C+LA%3BLove%2C+LA%3BTargoff%2C+IN%3BPandey%2C+J+P%3BMiller%2C+F+W&rft.aulast=Enz&rft.aufirst=LA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ACR, Paper No. 107 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of restriction endonucleases on HIV infection AN - 41820998; 2928672 AU - Sechler, JMG AU - Clouse, KA AU - Strebel, K AU - Weih, KA AU - Rosenberg, A S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41820998?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+restriction+endonucleases+on+HIV+infection&rft.au=Sechler%2C+JMG%3BClouse%2C+KA%3BStrebel%2C+K%3BWeih%2C+KA%3BRosenberg%2C+A+S&rft.aulast=Sechler&rft.aufirst=JMG&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 605 Third Avenue, 9th Floor, New York, NY 10158-0012, USA; Telephone: (212) 850-6543, Abstracts, Journal of Cellular Biochemistry, Supplement 17D, 1993, ISSN: 0730-2312 Poster Paper No. N 356 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tissue-specific regulation of IL-6 production by IL-4: Differential effects of IL-4 on monocytes and fibroblasts AN - 41813414; 2911565 AU - Donnelly, R P AU - Crofford, L J AU - Remmers, E AU - Obiri, N AU - Fenton, MJ AU - Wilder, R L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41813414?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Tissue-specific+regulation+of+IL-6+production+by+IL-4%3A+Differential+effects+of+IL-4+on+monocytes+and+fibroblasts&rft.au=Donnelly%2C+R+P%3BCrofford%2C+L+J%3BRemmers%2C+E%3BObiri%2C+N%3BFenton%2C+MJ%3BWilder%2C+R+L&rft.aulast=Donnelly&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 605 Third Avenue, 9th Floor, New York, NY 10158-0012, USA; Telephone: (212) 850-6543, Abstracts, Journal of Cellular Biochemistry, Supplement 17B 1993, ISSN: 0732-2312 Poster Paper no. EZ403 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Protein purification: Scientific and regulatory consideration on glycosylation, deamidation and oxidation of pharmaceutical proteins AN - 41813041; 2916240 AU - Liu, D T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41813041?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Protein+purification%3A+Scientific+and+regulatory+consideration+on+glycosylation%2C+deamidation+and+oxidation+of+pharmaceutical+proteins&rft.au=Liu%2C+D+T&rft.aulast=Liu&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 605 Third Avenue, 9th Floor, New York, NY 10158-0012, USA; Telephone: (212) 850-6543, Abstracts, Journal of Cellular Biochemistry, Supplement 17A 1993, ISSN: 0730-2312 Paper No. X1-023 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Interferon- gamma rapidly induces in human monocytes a novel DNA-binding factor that recognizes the gamma response region within the promoter of the gene for the high affinity Fc gamma receptor AN - 41810266; 2882799 AU - Finbloom, D S AU - Wilson, K C AU - Feldman, G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41810266?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Interferon-+gamma+rapidly+induces+in+human+monocytes+a+novel+DNA-binding+factor+that+recognizes+the+gamma+response+region+within+the+promoter+of+the+gene+for+the+high+affinity+Fc+gamma+receptor&rft.au=Finbloom%2C+D+S%3BWilson%2C+K+C%3BFeldman%2C+G&rft.aulast=Finbloom&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 605 Third Avenue, 9th Floor, New York, NY 10158-0012, USA; Telephone: (212) 850-6543, Abstracts, Journal of Cellular Biochemistry, Supplement 17A 1993, ISSN: 0730-2312 Poster Paper No. B135 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Interferon- gamma destabilizes granulocyte-macrophage colony-stimulating factor mRNA induced by interleukin-1 in murine endothelial cells AN - 41785928; 2819482 AU - Akahane, K AU - Pluznik, D H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41785928?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Interferon-+gamma+destabilizes+granulocyte-macrophage+colony-stimulating+factor+mRNA+induced+by+interleukin-1+in+murine+endothelial+cells&rft.au=Akahane%2C+K%3BPluznik%2C+D+H&rft.aulast=Akahane&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Springer-Verlag New York Inc., Journal Fulfillment Services, 44 Hartz Way, Seacaucus, NJ 07096, USA; Telephone: 1-800-SPRINGER; Telex: 12 59 94, Abstracts, Experimental Hematology, Volume 20, Number 6, July 1992, ISSN: 0301-472X Poster Paper No. 197 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Two distinct pathways, dependent and independent of Ca++, are involved in granulocyte macrophage-colony stimulating factor mRNA stabilization in murine T cells AN - 41776429; 2819201 AU - Iwai, Y AU - Cohen, R B AU - Pluznik, D H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41776429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Brain+research&rft.atitle=Selenium%2C+an+antioxidant%2C+attenuates+methamphetamine-induced+dopaminergic+toxicity+and+peroxynitrite+generation.&rft.au=Imam%2C+S+Z%3BAli%2C+S+F&rft.aulast=Imam&rft.aufirst=S&rft.date=2000-02-07&rft.volume=855&rft.issue=1&rft.spage=186&rft.isbn=&rft.btitle=&rft.title=Brain+research&rft.issn=00068993&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Springer-Verlag New York Inc., Journal Fulfillment Services, 44 Hartz Way, Seacaucus, NJ 07096, USA; 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Telephone: (415) 508-0118; Fax: (415) 595-4864 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Canda's for CBER AN - 41758641; 2829589 AU - Bell, R A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41758641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Canda%27s+for+CBER&rft.au=Trapnell%2C+C+B&rft.aulast=Trapnell&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: IBEX, 1070 Sixth Ave., Suite 309, Belmont, CA 94002, USA; Telephone: (415) 508-0118; Fax: (415) 595-4864 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Molecular mimicry between HIV 1 gp41 and HLA class II: Correlation between the generation of crossreactive antibodies, T cell function, and disease progression in infected individuals AN - 41723600; 2654543 AU - Golding, H AU - Clerici, M AU - Mann, D AU - Shearer, G M AU - Blackburn, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41723600?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Molecular+mimicry+between+HIV+1+gp41+and+HLA+class+II%3A+Correlation+between+the+generation+of+crossreactive+antibodies%2C+T+cell+function%2C+and+disease+progression+in+infected+individuals&rft.au=Golding%2C+H%3BClerici%2C+M%3BMann%2C+D%3BShearer%2C+G+M%3BBlackburn%2C+R&rft.aulast=Golding&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Attn.: Cecilia Avico, VIIth International Conference on AIDS, Istituto Superiore di Sanita, Laboratory of Virology, Viale Regina Elena, 299, 00161 Rome, Italy, Abstracts Paper No. M.A.16 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Chemically induced mutants of the CEM cell line demonstrate partial blockade of their PKC-dependent pathways and reduced susceptibility to HIV 1 infection AN - 41715060; 2656052 AU - Hillman, K AU - Gruber, M F AU - Kaufman, J AU - Blackburn, R AU - Manischewitz, J AU - Norcross, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41715060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Pivotal+efficacy+requirement+in+designing+acceptable+phase+III+trail+to+support+a+PLA&rft.au=Woodcock%2C+J&rft.aulast=Woodcock&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Attn.: Cecilia Avico, VIIth International Conference on AIDS, Istituto Superiore di Sanita, Laboratory of Virology, Viale Regina Elena, 299, 00161 Rome, Italy, Abstracts Poster Paper No. M.A.1140 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of HIV-1 from chronically infected promonocytic cells by chemical carcinogens AN - 41712330; 2656567 AU - Hewlett, I AU - Joshi, B AU - Riordan, G AU - Lee, G AU - Pollock, L AU - Epstein, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41712330?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction+of+HIV-1+from+chronically+infected+promonocytic+cells+by+chemical+carcinogens&rft.au=Hewlett%2C+I%3BJoshi%2C+B%3BRiordan%2C+G%3BLee%2C+G%3BPollock%2C+L%3BEpstein%2C+J&rft.aulast=Hewlett&rft.aufirst=I&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Attn.: Cecilia Avico, VIIth International Conference on AIDS, Istituto Superiore di Sanita, Laboratory of Virology, Viale Regina Elena, 299, 00161 Rome, Italy, Abstracts Poster Paper No. M.A.1190 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cytokines and cellular therapy AN - 41705920; 2690911 AU - Gunter, K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41705920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Cytokines+and+cellular+therapy&rft.au=Gunter%2C+K&rft.aulast=Gunter&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: BioEast '92, 1651 Third Avenue, Suite 301, New York, NY 10128, USA. 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N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In vitro and in vivo activity of HIV protease inhibitors in an animal retroviral model AN - 41665785; 2665593 AU - Ussery, MA AU - Black, P L AU - Downs, M B AU - Lewis, M G AU - Lambert, D M AU - Dreyer, G B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41665785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=In+vitro+and+in+vivo+activity+of+HIV+protease+inhibitors+in+an+animal+retroviral+model&rft.au=Ussery%2C+MA%3BBlack%2C+P+L%3BDowns%2C+M+B%3BLewis%2C+M+G%3BLambert%2C+D+M%3BDreyer%2C+G+B&rft.aulast=Ussery&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Attn.: Cecilia Avico, VIIth International Conference on AIDS, Istituto Superiore di Sanita, Laboratory of Virology, Viale Regina Elena, 299, 00161 Rome, Italy, Abstracts Paper No. W.A.68 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bacteriophage typing of Listeria monocytogenes isolated from foods AN - 41647469; 2534630 AU - Estela, L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41647469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Bacteriophage+typing+of+Listeria+monocytogenes+isolated+from+foods&rft.au=Estela%2C+L&rft.aulast=Estela&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Poster Paper No. P33 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of extracellular calcium on inhibition of dye coupling among cardiac myocytes by halogenated hydrocarbons AN - 41647143; 2525945 AU - Breitenstein, MJ AU - Toraason, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41647143?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+extracellular+calcium+on+inhibition+of+dye+coupling+among+cardiac+myocytes+by+halogenated+hydrocarbons&rft.au=Breitenstein%2C+MJ%3BToraason%2C+M&rft.aulast=Breitenstein&rft.aufirst=MJ&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evidence that lipopolysaccharide from Brucella abortus stimulates murine B cells directly AN - 41644452; 2511552 AU - Goldstein, J S AU - Frasch, C AU - Hernandez, D AU - Beining, PR AU - Betts, M AU - Hoffman, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41644452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Evidence+that+lipopolysaccharide+from+Brucella+abortus+stimulates+murine+B+cells+directly&rft.au=Goldstein%2C+J+S%3BFrasch%2C+C%3BHernandez%2C+D%3BBeining%2C+PR%3BBetts%2C+M%3BHoffman%2C+T&rft.aulast=Goldstein&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Generation of Bordetella pertussis antigen-specific memory B lymphocytes in the respiratory tract AN - 41635472; 2536537 AU - Amsbaugh, D F AU - Manclark, C R AU - Shahin, R D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41635472?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+reduced+dietary+protein+levels+on+the+early+resistance+of+mice+to+virulent+and+avirulent+Listeria+species&rft.au=Smith%2C+B+G%3BWess%2C+JA%3BRhea%2C+U+S%3BShah%2C+D+B%3BPetro%2C+T+M&rft.aulast=Smith&rft.aufirst=B&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Poster Paper No. B150 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Medical studies of the poisonous land and sea snakes in and around Saudi Arabia AN - 41634525; 2494045 AU - Vick, JA AU - Herman, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41634525?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Shelf+life+of+modified+atmosphere-packaged+fresh+salmon+fillets+stored+under+refrigeration+and+temperature+abuse+conditions&rft.au=Reddy%2C+N+R%3BVillanueva%2C+M%3BKautter%2C+DA&rft.aulast=Reddy&rft.aufirst=N&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Metabolism of acrylonitrile by Klebsiella pneumoniae AN - 41630276; 2538520 AU - Nawaz, M AU - Franklin, W AU - Campbell, W AU - Heinz, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41630276?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Metabolism+of+acrylonitrile+by+Klebsiella+pneumoniae&rft.au=Nawaz%2C+M%3BFranklin%2C+W%3BCampbell%2C+W%3BHeinz%2C+T&rft.aulast=Nawaz&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Paper No. K95 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Flow microfluorimetric analysis of bacterial phagocytosis by J774A.1 macrophages AN - 41630053; 2520739 AU - Raybourne, R B AU - Bunning, V K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41630053?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Flow+microfluorimetric+analysis+of+bacterial+phagocytosis+by+J774A.1+macrophages&rft.au=Raybourne%2C+R+B%3BBunning%2C+V+K&rft.aulast=Raybourne&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Strain-dependent restricted V sub(H) usage by anti-bacterial levan monoclonal antibodies AN - 41627428; 2530791 AU - Boswell, C AU - Goodnight, J AU - Irwin, D AU - Stein, K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41627428?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Strain-dependent+restricted+V+sub%28H%29+usage+by+anti-bacterial+levan+monoclonal+antibodies&rft.au=Boswell%2C+C%3BGoodnight%2C+J%3BIrwin%2C+D%3BStein%2C+K&rft.aulast=Boswell&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Copper status in weanling rats fed low levels of inorganic tin AN - 41624190; 2514405 AU - Rader, JI AU - Hight, S C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41624190?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Copper+status+in+weanling+rats+fed+low+levels+of+inorganic+tin&rft.au=Rader%2C+JI%3BHight%2C+S+C&rft.aulast=Rader&rft.aufirst=JI&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Monoclonal antibody analysis of benzopyrene-induced fetal T cell antigens AN - 41623783; 2528988 AU - Herd, Z AU - Henningsen, G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41623783?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Monoclonal+antibody+analysis+of+benzopyrene-induced+fetal+T+cell+antigens&rft.au=Herd%2C+Z%3BHenningsen%2C+G&rft.aulast=Herd&rft.aufirst=Z&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Neurochemical effects of prenatal ethanol administration in rat AN - 41622169; 2508220 AU - Briggs, F AU - Headings, V AU - Pradhan, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41622169?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Neurochemical+effects+of+prenatal+ethanol+administration+in+rat&rft.au=Briggs%2C+F%3BHeadings%2C+V%3BPradhan%2C+S&rft.aulast=Briggs&rft.aufirst=F&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Preclinical considerations for the development of intravitreal drug products AN - 41622004; 3460292 AU - Weir, A AU - Chambers, W AU - Chen, C AU - Chen, Z AU - Mukherjee, A AU - Wilson, S AU - Yang, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41622004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Preclinical+considerations+for+the+development+of+intravitreal+drug+products&rft.au=Weir%2C+A%3BChambers%2C+W%3BChen%2C+C%3BChen%2C+Z%3BMukherjee%2C+A%3BWilson%2C+S%3BYang%2C+J&rft.aulast=Weir&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 1524 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Major neutralizing epitope of HIV-1 depends on protein conformation and maps to the carboxyl third of GP 120 AN - 41620233; 2503141 AU - Berkower, I AU - Murphy, D AU - Smith, C AU - Smith, GE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41620233?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Major+neutralizing+epitope+of+HIV-1+depends+on+protein+conformation+and+maps+to+the+carboxyl+third+of+GP+120&rft.au=Berkower%2C+I%3BMurphy%2C+D%3BSmith%2C+C%3BSmith%2C+GE&rft.aulast=Berkower&rft.aufirst=I&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Distribution and expression of pneumolysin in Streptococcus pneumoniae AN - 41618836; 2527343 AU - Li, J AU - Tai, S AU - Nguyen, N AU - Lee, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41618836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Distribution+and+expression+of+pneumolysin+in+Streptococcus+pneumoniae&rft.au=Li%2C+J%3BTai%2C+S%3BNguyen%2C+N%3BLee%2C+C&rft.aulast=Li&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Estimating historical respirable crystalline silica exposures for Chinese pottery workers and iron/copper, tin, and tungsten miners AN - 41617401; 3466045 AU - Zhuang, Z AU - Hearl, F AU - Chen, B AU - McCawley, M AU - Gao, P AU - Soderholm, S AU - Chen, W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41617401?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Estimating+historical+respirable+crystalline+silica+exposures+for+Chinese+pottery+workers+and+iron%2Fcopper%2C+tin%2C+and+tungsten+miners&rft.au=Zhuang%2C+Z%3BHearl%2C+F%3BChen%2C+B%3BMcCawley%2C+M%3BGao%2C+P%3BSoderholm%2C+S%3BChen%2C+W&rft.aulast=Zhuang&rft.aufirst=Z&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 2700 Prosperity Ave., Suite 250, Fairfax, VA 22031-4307, USA; phone: 703-849-8888; email: aiche@laserreg.com; URL: www.aiha.org/aiche99/info.html, Abstracs available. 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Poster Paper No. 445 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - How the draft guidance evolved into the new guidance document AN - 41616420; 3462668 AU - McCormack, J F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41616420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=How+the+draft+guidance+evolved+into+the+new+guidance+document&rft.au=McCormack%2C+J+F&rft.aulast=McCormack&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Drug Information Association, 501 Office Center Drive, Suite 450, Fort Washington, PA 19034-3211, USA; phone: 215-628-2288; fax: 215-641-1229; email: brax@diahome.org; URL: www.diahome.org, Abstracts available. 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N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Antibody responses of MHC cogenic mice to the human CD4 site binding gp120 of HIV-1 AN - 41615795; 2503154 AU - Reeves, J P AU - Lo, C-Y AU - Epstein, S L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41615795?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Antibody+responses+of+MHC+cogenic+mice+to+the+human+CD4+site+binding+gp120+of+HIV-1&rft.au=Reeves%2C+J+P%3BLo%2C+C-Y%3BEpstein%2C+S+L&rft.aulast=Reeves&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Regulatory update on Thailand and regional harmonization AN - 41614256; 3462508 AU - Na Songkhia, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41614256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Regulatory+update+on+Thailand+and+regional+harmonization&rft.au=Na+Songkhia%2C+M&rft.aulast=Na+Songkhia&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Drug Information Association, 501 Office Center Drive, Suite 450, Fort Washington, PA 19034-3211, USA; phone: 215-628-2288; fax: 215-641-1229; email: brax@diahome.org; URL: www.diahome.org, Abstracts available. 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N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Either umuDC or sam is sufficient for UV mutagenesis in Salmonella typhimurium AN - 41612352; 2533355 AU - Koch, W H AU - Cebula, T A AU - Franklin, S B AU - Foster, P L AU - Eisenstadt, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41612352?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Either+umuDC+or+sam+is+sufficient+for+UV+mutagenesis+in+Salmonella+typhimurium&rft.au=Koch%2C+W+H%3BCebula%2C+T+A%3BFranklin%2C+S+B%3BFoster%2C+P+L%3BEisenstadt%2C+E&rft.aulast=Koch&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Poster Paper No. H14 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Video exposure monitoring of jet fuel tank entry personnel at U.S. Air Force and commercial maintenance facilities AN - 41612282; 3466022 AU - Jensen, P AU - Dower, J AU - Kinnes, G AU - Mead, K AU - Watkins, D AU - Carlton, G AU - Smith, L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41612282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Video+exposure+monitoring+of+jet+fuel+tank+entry+personnel+at+U.S.+Air+Force+and+commercial+maintenance+facilities&rft.au=Jensen%2C+P%3BDower%2C+J%3BKinnes%2C+G%3BMead%2C+K%3BWatkins%2C+D%3BCarlton%2C+G%3BSmith%2C+L&rft.aulast=Jensen&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 2700 Prosperity Ave., Suite 250, Fairfax, VA 22031-4307, USA; phone: 703-849-8888; email: aiche@laserreg.com; URL: www.aiha.org/aiche99/info.html, Abstracs available. 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Poster Paper No. 422 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Morphological changes in rats fed beta -carotene and varied protein sources AN - 41611574; 2500390 AU - Jenkins, MY AU - Sheikh, N M AU - Mitchell, G V AU - Grundel, G AU - Blakely Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41611574?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Morphological+changes+in+rats+fed+beta+-carotene+and+varied+protein+sources&rft.au=Jenkins%2C+MY%3BSheikh%2C+N+M%3BMitchell%2C+G+V%3BGrundel%2C+G%3BBlakely&rft.aulast=Jenkins&rft.aufirst=MY&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Review of the physiological variables and constants used in the Coburn-Forster-Kane equation to predict carboxyhemoglobin levels AN - 41611063; 3465961 AU - Burr, G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41611063?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Review+of+the+physiological+variables+and+constants+used+in+the+Coburn-Forster-Kane+equation+to+predict+carboxyhemoglobin+levels&rft.au=Burr%2C+G&rft.aulast=Burr&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 2700 Prosperity Ave., Suite 250, Fairfax, VA 22031-4307, USA; phone: 703-849-8888; email: aiche@laserreg.com; URL: www.aiha.org/aiche99/info.html, Abstracs available. 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Poster Paper No. 366 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Potential problematical glycoalkaloids in pork chops AN - 41608440; 3459045 AU - Betz, J M AU - Garland, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41608440?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Potential+problematical+glycoalkaloids+in+pork+chops&rft.au=Betz%2C+J+M%3BGarland%2C+T&rft.aulast=Betz&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 277 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of the terminal lipid of group C meningococcal polysaccharide in immunoassays AN - 41606723; 2537285 AU - Arakere, G AU - Frasch, CE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41606723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+industrial+health&rft.atitle=Breast-feeding+exposure+of+infants+to+selected+pesticides%3A+a+public+health+viewpoint.&rft.au=Pohl%2C+H+R%3BTylenda%2C+C+A&rft.aulast=Pohl&rft.aufirst=H&rft.date=2000-02-01&rft.volume=16&rft.issue=2&rft.spage=65&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+industrial+health&rft.issn=07482337&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Paper No. J12 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Binding specificity of Mycoplasma hominis 1620 AN - 41606306; 2537162 AU - Olson, L D AU - Gilbert, A A AU - Barile, M F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41606306?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Binding+specificity+of+Mycoplasma+hominis+1620&rft.au=Olson%2C+L+D%3BGilbert%2C+A+A%3BBarile%2C+M+F&rft.aulast=Olson&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Paper No. G34 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bacterial plasmids as indicators of potential fecal contamination to shellfish-growing waters AN - 41606063; 2537037 AU - Motes, ML Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41606063?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Bacterial+plasmids+as+indicators+of+potential+fecal+contamination+to+shellfish-growing+waters&rft.au=Motes%2C+ML+Jr&rft.aulast=Motes&rft.aufirst=ML&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Paper No. Q155 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Hemagglutination properties of capsular polysaccharide from Salmonella enteritidis AN - 41605665; 2534147 AU - Gayle, AB AU - Hanes, DE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41605665?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Hemagglutination+properties+of+capsular+polysaccharide+from+Salmonella+enteritidis&rft.au=Gayle%2C+AB%3BHanes%2C+DE&rft.aulast=Gayle&rft.aufirst=AB&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Poster Paper No. P16 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of exposure to asphalt fume condensate (AFC) on acute inflammatory responses AN - 41605132; 3459328 AU - Ma, JYC AU - Barger, M W AU - Kreich, A J AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41605132?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+exposure+to+asphalt+fume+condensate+%28AFC%29+on+acute+inflammatory+responses&rft.au=Ma%2C+JYC%3BBarger%2C+M+W%3BKreich%2C+A+J%3BCastranova%2C+V&rft.aulast=Ma&rft.aufirst=JYC&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 560 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Adverse responses to semisynthetic metal working fluids in B6C3F1 mice AN - 41604710; 3459121 AU - Al-Humadi, N H AU - Kommineni, C AU - Shvedova, A A AU - Battelli, L AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41604710?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Adverse+responses+to+semisynthetic+metal+working+fluids+in+B6C3F1+mice&rft.au=Al-Humadi%2C+N+H%3BKommineni%2C+C%3BShvedova%2C+A+A%3BBattelli%2C+L%3BCastranova%2C+V&rft.aulast=Al-Humadi&rft.aufirst=N&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 353 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Antagonism toward Listeria monocytogenes by competitors in enrichment culture AN - 41604672; 2537238 AU - Dallas, H L AU - Hitchins, AD Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41604672?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Antagonism+toward+Listeria+monocytogenes+by+competitors+in+enrichment+culture&rft.au=Dallas%2C+H+L%3BHitchins%2C+AD&rft.aulast=Dallas&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Paper No. P41 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Human pathogens in a shellfish growing area contributed by non-point sources AN - 41604358; 2537033 AU - Kaysner, C AU - Abeyta, C Jr AU - Stott, R AU - Wetherington, J AU - Colburn, K AU - Wekell, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41604358?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Human+pathogens+in+a+shellfish+growing+area+contributed+by+non-point+sources&rft.au=Kaysner%2C+C%3BAbeyta%2C+C+Jr%3BStott%2C+R%3BWetherington%2C+J%3BColburn%2C+K%3BWekell%2C+M&rft.aulast=Kaysner&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Paper No. Q154 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of oxytetracycline on development and persistence of antibiotic-resistant bacteria in catfish ponds AN - 41602207; 2542658 AU - Depaola, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41602207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+oxytetracycline+on+development+and+persistence+of+antibiotic-resistant+bacteria+in+catfish+ponds&rft.au=Depaola%2C+A&rft.aulast=Depaola&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASM, 1325 Massachusetts Avenue NW, Washington, DC 20005, USA, Poster Paper No. Q251 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Genotoxicity and immunological changes in isocyanate exposed brown Norway rats AN - 41601915; 3459377 AU - Siegel, P D AU - Zhong, B-Z AU - Lawrence, TE AU - Lewis, D M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41601915?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Genotoxicity+and+immunological+changes+in+isocyanate+exposed+brown+Norway+rats&rft.au=Siegel%2C+P+D%3BZhong%2C+B-Z%3BLawrence%2C+TE%3BLewis%2C+D+M&rft.aulast=Siegel&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 609 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In vitro percutaneous absorption and metabolism of 2-nitro-p-phenylenediamine in human and fuzzy rat skin AN - 41601201; 3459114 AU - Yourick, J J AU - Bronaugh, R L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41601201?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=In+vitro+percutaneous+absorption+and+metabolism+of+2-nitro-p-phenylenediamine+in+human+and+fuzzy+rat+skin&rft.au=Yourick%2C+J+J%3BBronaugh%2C+R+L&rft.aulast=Yourick&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 346 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Consumption of dietary fibers with different potentials to alter colonic carcinogenesis differentially affects colonic luminal immunoreactive EGF levels in rats AN - 41600038; 2514547 AU - Calvert, R J AU - Satchithanandam, S AU - Schaudies, R P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41600038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Consumption+of+dietary+fibers+with+different+potentials+to+alter+colonic+carcinogenesis+differentially+affects+colonic+luminal+immunoreactive+EGF+levels+in+rats&rft.au=Calvert%2C+R+J%3BSatchithanandam%2C+S%3BSchaudies%2C+R+P&rft.aulast=Calvert&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - cAMP inhibits T cell receptor-induced hydrolysis of inositol phospholipids at a level proximal to phospholipase C activation AN - 41599365; 2525647 AU - Alava, MA AU - DeBell, KE AU - Taplits AU - Hoffman, T AU - Bonvini, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41599365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=cAMP+inhibits+T+cell+receptor-induced+hydrolysis+of+inositol+phospholipids+at+a+level+proximal+to+phospholipase+C+activation&rft.au=Alava%2C+MA%3BDeBell%2C+KE%3BTaplits%3BHoffman%2C+T%3BBonvini%2C+E&rft.aulast=Alava&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Behavioral toxicity of ethanol in rats AN - 41598706; 3460460 AU - Popke, E J AU - Allen AU - Fogle, C M AU - Paule, M G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41598706?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Behavioral+toxicity+of+ethanol+in+rats&rft.au=Popke%2C+E+J%3BAllen%3BFogle%2C+C+M%3BPaule%2C+M+G&rft.aulast=Popke&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 1692 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differential effects of trimethyltin on tasks related to time estimation and appetitive motivation in rats AN - 41598140; 3460480 AU - Mayorga, A J AU - Fogle, C M AU - Paule, M G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41598140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Differential+effects+of+trimethyltin+on+tasks+related+to+time+estimation+and+appetitive+motivation+in+rats&rft.au=Mayorga%2C+A+J%3BFogle%2C+C+M%3BPaule%2C+M+G&rft.aulast=Mayorga&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 1712 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Animal models design: Asking the right questions AN - 41597799; 3462228 AU - Witten, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41597799?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Animal+models+design%3A+Asking+the+right+questions&rft.au=Witten%2C+C&rft.aulast=Witten&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Cambridge Healthtech Institute, 1037 Chestnut Street, Newton Upper Falls, MA 02464, USA; phone: 617-630-1300; fax: 617-630-1325; email: chi@healthtech.com; URL: http://www.healthtech.com, Abstracts available. Price $195 + S & H. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Purification and characterization of soluble EGF receptors secreted from A431 cells AN - 41597503; 2527587 AU - Liu, S-Y AU - Williams, T AU - Komoriya, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41597503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Purification+and+characterization+of+soluble+EGF+receptors+secreted+from+A431+cells&rft.au=Liu%2C+S-Y%3BWilliams%2C+T%3BKomoriya%2C+A&rft.aulast=Liu&rft.aufirst=S-Y&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Safety assessment of cosmetic ingredients and color additives: Evaluation of a quantitative structure-toxicity relationship approach for predicting toxicity AN - 41596816; 3460296 AU - Milstein AU - Yourick, J J AU - Bronaugh, R L AU - Wamer, W G AU - Lowther, D K AU - Meyers, M B AU - Scher, AL AU - Bell, S J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41596816?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Safety+assessment+of+cosmetic+ingredients+and+color+additives%3A+Evaluation+of+a+quantitative+structure-toxicity+relationship+approach+for+predicting+toxicity&rft.au=Milstein%3BYourick%2C+J+J%3BBronaugh%2C+R+L%3BWamer%2C+W+G%3BLowther%2C+D+K%3BMeyers%2C+M+B%3BScher%2C+AL%3BBell%2C+S+J&rft.aulast=Milstein&rft.aufirst=&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 1528 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Four protectors in search of a rating system AN - 41596348; 3448552 AU - Murphy, W J AU - Franks, J R AU - Harris, DA AU - Johnson, J L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41596348?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Four+protectors+in+search+of+a+rating+system&rft.au=Murphy%2C+W+J%3BFranks%2C+J+R%3BHarris%2C+DA%3BJohnson%2C+J+L&rft.aulast=Murphy&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Institute of Physics, 500 Sunnydale Boulevard, Woodbury, NY 11797, USA; URL: asa.aip.org, Abstracts available. Price $100. Poster Paper No. 3aNSb12 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of intermittent exposures of aflatoxin B sub(1) on hepatic and testicular glutathione S-transferase in rats AN - 41595449; 3459678 AU - Sahu, S C AU - Chou, M W AU - Sotomayor, R E AU - Hinton, D M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41595449?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+intermittent+exposures+of+aflatoxin+B+sub%281%29+on+hepatic+and+testicular+glutathione+S-transferase+in+rats&rft.au=Sahu%2C+S+C%3BChou%2C+M+W%3BSotomayor%2C+R+E%3BHinton%2C+D+M&rft.aulast=Sahu&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 910 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - PK compartmental (COM) modeling and dose (D) regimen (REG) analysis for concentration controlled trials (CCT) of suramin (SUR) in cancer (CA) using difference equation simulation (DES) AN - 41594253; 2417511 AU - Lieberman, R AU - Katzper, M AU - Peck, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41594253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=PK+compartmental+%28COM%29+modeling+and+dose+%28D%29+regimen+%28REG%29+analysis+for+concentration+controlled+trials+%28CCT%29+of+suramin+%28SUR%29+in+cancer+%28CA%29+using+difference+equation+simulation+%28DES%29&rft.au=Lieberman%2C+R%3BKatzper%2C+M%3BPeck%2C+C&rft.aulast=Lieberman&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Ms. Elaine Galasso, 1718 Gallagher Road, Norristown, PA 19401-2800, USA. Telephone: (215) 825-3838. Fax: (215) 834-8652., Poster Paper No. PI-2 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Disease modification: A regulatory perspective AN - 41594029; 3454018 AU - Witter, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41594029?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Disease+modification%3A+A+regulatory+perspective&rft.au=Witter%2C+J&rft.aulast=Witter&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society of Clinical Pharmacology and Therapeutics, 117 West Ridge Pike, Suite 2, Conshohocken, PA 19428-1216, USA; phone: 610-825-3838; fax: 610-834-8652; email: ascpt@aol.com; URL: www.ascpt.org, Abstracts available. Price $20. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Acute inhalation toxicity of ethylamine, diethylamine and triethylamine - Effects on rodent nasal passages AN - 41590932; 3459319 AU - Lynch, D W AU - Schueler, R L AU - Gorgacz, E J AU - Cheever, K L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41590932?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Mercury+induces+regional+and+cell-specific+stress+protein+expression+in+rat+kidney.&rft.au=Goering%2C+P+L%3BFisher%2C+B+R%3BNoren%2C+B+T%3BPapaconstantinou%2C+A%3BRojko%2C+J+L%3BMarler%2C+R+J&rft.aulast=Goering&rft.aufirst=P&rft.date=2000-02-01&rft.volume=53&rft.issue=2&rft.spage=447&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 551 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Expression of FGF receptor (FLG) in embryonal rhabdomyosarcoma cells and glioblastomas: Potential involvement in autocrine stimulation AN - 41590485; 2465433 AU - Ruta, M AU - Neiger, N AU - Pollock, L AU - Winkles, J AU - Epstein, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41590485?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Expression+of+FGF+receptor+%28FLG%29+in+embryonal+rhabdomyosarcoma+cells+and+glioblastomas%3A+Potential+involvement+in+autocrine+stimulation&rft.au=Ruta%2C+M%3BNeiger%2C+N%3BPollock%2C+L%3BWinkles%2C+J%3BEpstein%2C+J&rft.aulast=Ruta&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Dep., 7th Floor, 605 Third Avenue, New York, NY 10158, USA, Journal of Cellular Biochemistry; Supplement 15F, 1991; ISSN: 0730-2312 Poster Paper No. CF 216 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Expression of immunoglobulin heavy chain variable gene (V sub(H)) in B-chronic lymphocytic leukemia (B-CLL) and B-prolymphocytic leukemia (B-PLL) cell lines: "Restricted" usage of V sub(H)3 family AN - 41589956; 2487437 AU - Bertin, P A AU - Marti, GE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41589956?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Expression+of+immunoglobulin+heavy+chain+variable+gene+%28V+sub%28H%29%29+in+B-chronic+lymphocytic+leukemia+%28B-CLL%29+and+B-prolymphocytic+leukemia+%28B-PLL%29+cell+lines%3A+%22Restricted%22+usage+of+V+sub%28H%293+family&rft.au=Bertin%2C+P+A%3BMarti%2C+GE&rft.aulast=Bertin&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 7th Floor, 605 Third Avenue, New York, NY 10158, USA, Journal of Cellular Biochemistry; Supplement 15G, 1991; ISSN: 0730-2312 Poster Paper No. S 209 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of acute ibogaine administration on the performance of complex operant tasks in rats AN - 41587226; 3460117 AU - Xu, Z AU - Mayorga, A J AU - Fogle, C M AU - Scallet, A AU - Chang, L W AU - Slikker, W AU - Paule, M G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41587226?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+acute+ibogaine+administration+on+the+performance+of+complex+operant+tasks+in+rats&rft.au=Xu%2C+Z%3BMayorga%2C+A+J%3BFogle%2C+C+M%3BScallet%2C+A%3BChang%2C+L+W%3BSlikker%2C+W%3BPaule%2C+M+G&rft.aulast=Xu&rft.aufirst=Z&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 1349 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - IL-1 expression in human monocytes is transcriptionally and posttranscriptionally regulated by IL-4 AN - 41584816; 2443070 AU - Donnelly, R P AU - Fenton, MJ AU - Kaufman, J D AU - Gerrard, T L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41584816?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=IL-1+expression+in+human+monocytes+is+transcriptionally+and+posttranscriptionally+regulated+by+IL-4&rft.au=Donnelly%2C+R+P%3BFenton%2C+MJ%3BKaufman%2C+J+D%3BGerrard%2C+T+L&rft.aulast=Donnelly&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 7th Floor, 605 Third Avenue, New York, NY 10158, USA, Journal of Cellular Biochemistry; Supplement 15E, 1991; ISSN: 0730-2312 Paper No. O 304 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Toxicologic effects of 13-week inhalation exposure to N,N-dimethylformamide in rats and mice AN - 41584633; 2434614 AU - Lynch, D W AU - Placke, ME AU - Persing, R L AU - Ryan, MJ AU - Kurtz, P J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41584633?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Toxicologic+effects+of+13-week+inhalation+exposure+to+N%2CN-dimethylformamide+in+rats+and+mice&rft.au=Lynch%2C+D+W%3BPlacke%2C+ME%3BPersing%2C+R+L%3BRyan%2C+MJ%3BKurtz%2C+P+J&rft.aulast=Lynch&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th Street, NW, Suite 1100, Washington, DC 20005, USA. Telephone: (202) 371-1393. Fax: (202) 371-1090., Poster Paper No. 1234 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tetrandrine inhibits synthesis of disaturated phosphatidylcholines in rat alveolar type II cells AN - 41584627; 2523653 AU - Ma, JYC AU - Bowman, L AU - Ma, JKH AU - Miles, PR Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41584627?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Tetrandrine+inhibits+synthesis+of+disaturated+phosphatidylcholines+in+rat+alveolar+type+II+cells&rft.au=Ma%2C+JYC%3BBowman%2C+L%3BMa%2C+JKH%3BMiles%2C+PR&rft.aulast=Ma&rft.aufirst=JYC&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts, FASEB Journal Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - bST safety and human consumption AN - 41582797; 2420566 AU - Guyer, C G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:MUTIDISCIPLINARY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41582797?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=bST+safety+and+human+consumption&rft.au=Guyer%2C+C+G&rft.aulast=Guyer&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: AAAS Books, Dept. 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Fax: (301) 843-0159., Abstracts, 91-02, $8.00 members/$10.00 non-members plus $4.00 postage/handling N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - o-Toluidine blood protein adducts: HPLC analysis with fluorescence detection after a single dose in the adult male rat AN - 41582747; 2431836 AU - Cheever, K L AU - DeBord, G D AU - Swearengin, T F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41582747?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=o-Toluidine+blood+protein+adducts%3A+HPLC+analysis+with+fluorescence+detection+after+a+single+dose+in+the+adult+male+rat&rft.au=Cheever%2C+K+L%3BDeBord%2C+G+D%3BSwearengin%2C+T+F&rft.aulast=Cheever&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th Street, NW, Suite 1100, Washington, DC 20005, USA. Telephone: (202) 371-1393. Fax: (202) 371-1090., Poster Paper No. 455 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative metabolism of bis(2-methoxy-ethyl)ether in isolated rat hepatocytes and in the intact rat AN - 41581483; 2430795 AU - Richards, DE AU - Begley, K B AU - DeBord, D G AU - Cheever, K L AU - Weigel, W W AU - Savage, R E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41581483?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparative+metabolism+of+bis%282-methoxy-ethyl%29ether+in+isolated+rat+hepatocytes+and+in+the+intact+rat&rft.au=Richards%2C+DE%3BBegley%2C+K+B%3BDeBord%2C+D+G%3BCheever%2C+K+L%3BWeigel%2C+W+W%3BSavage%2C+R+E&rft.aulast=Richards&rft.aufirst=DE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th Street, NW, Suite 1100, Washington, DC 20005, USA. Telephone: (202) 371-1393. Fax: (202) 371-1090., Poster Paper No. 164 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of PK/PD modeling in drug regulation AN - 41576412; 3462896 AU - Miller, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41576412?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+PK%2FPD+modeling+in+drug+regulation&rft.au=Miller%2C+R&rft.aulast=Miller&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Drug Information Association, 501 Office Center Drive, Suite 450, Fort Washington, PA 19034-3211, USA; phone: 215-628-2288; fax: 215-641-1229; email: brax@diahome.org; URL: www.diahome.org, Abstracts available. 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N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Transgenic mice and model assay systems for genotoxicity and human diseases AN - 41573195; 2429549 AU - Cordaro, J C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41573195?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Transgenic+mice+and+model+assay+systems+for+genotoxicity+and+human+diseases&rft.au=Cordaro%2C+J+C&rft.aulast=Cordaro&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Wiley & Sons, Inc., 605 Third Avenue, 7th Floor, New York, NY 10158, USA, Journal of Cellular Biochemistry; ISSN: 0730-2312; Supplement 15B, 1991 Paper No. 9 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differential effects of sera on basal and chemical-induced cell proliferation and differentiation in rat embryonic midbrain and limb bud cell micro-mass culture AN - 41567895; 3459082 AU - Park, K S AU - Han, SY AU - Park, K L AU - Hong, J T AU - Kim, H S AU - Park, HJ AU - Kook, S S AU - Lee, R D AU - Choi, Y J AU - Jang, S J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41567895?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Differential+effects+of+sera+on+basal+and+chemical-induced+cell+proliferation+and+differentiation+in+rat+embryonic+midbrain+and+limb+bud+cell+micro-mass+culture&rft.au=Park%2C+K+S%3BHan%2C+SY%3BPark%2C+K+L%3BHong%2C+J+T%3BKim%2C+H+S%3BPark%2C+HJ%3BKook%2C+S+S%3BLee%2C+R+D%3BChoi%2C+Y+J%3BJang%2C+S+J&rft.aulast=Park&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 314 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Fate of 2,4-dichlorophenoxyacetic acid following oral administration in channel catfish AN - 41563686; 2465040 AU - Plakas, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 5500:GEOSCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41563686?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Fate+of+2%2C4-dichlorophenoxyacetic+acid+following+oral+administration+in+channel+catfish&rft.au=Plakas%2C+S&rft.aulast=Plakas&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASTM, 1916 Race Street, Philadelphia, PA 19103, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Enhancement of conditioned avoidance response (CAR) by B-blockers, N-methyl-D-asparate (NMDA) and acridne 1-OH-THA in mice AN - 41561755; 2432334 AU - Yen-Koo, H AU - Rosloff, B AU - Zhang, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41561755?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Enhancement+of+conditioned+avoidance+response+%28CAR%29+by+B-blockers%2C+N-methyl-D-asparate+%28NMDA%29+and+acridne+1-OH-THA+in+mice&rft.au=Yen-Koo%2C+H%3BRosloff%2C+B%3BZhang%2C+J&rft.aulast=Yen-Koo&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th Street, NW, Suite 1100, Washington, DC 20005, USA. Telephone: (202) 371-1393. Fax: (202) 371-1090., Poster Paper No. 591 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Defining relevant animal species for toxicity evaluation of biologic therapeutics; Critical groundwork for basing preclinical toxicity program strategies AN - 41561604; 3458958 AU - Black, LE AU - Green, MD Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41561604?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Defining+relevant+animal+species+for+toxicity+evaluation+of+biologic+therapeutics%3B+Critical+groundwork+for+basing+preclinical+toxicity+program+strategies&rft.au=Black%2C+LE%3BGreen%2C+MD&rft.aulast=Black&rft.aufirst=LE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Paper No. 190 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Endocrine disruptor knowledge base (EKB) AN - 41559894; 3460661 AU - Tong, W AU - Perkins, R AU - Anson, J AU - Branham, W AU - Blair, R AU - Hass, B AU - Fang, H AU - Shi, L AU - Chen, Y AU - Meehan, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41559894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Endocrine+disruptor+knowledge+base+%28EKB%29&rft.au=Tong%2C+W%3BPerkins%2C+R%3BAnson%2C+J%3BBranham%2C+W%3BBlair%2C+R%3BHass%2C+B%3BFang%2C+H%3BShi%2C+L%3BChen%2C+Y%3BMeehan%2C+J&rft.aulast=Tong&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 1893 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Immunogenicity of monoclonal antibodies: Conventional versus engineered AN - 41558147; 3454023 AU - Stein, KE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41558147?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Immunogenicity+of+monoclonal+antibodies%3A+Conventional+versus+engineered&rft.au=Stein%2C+KE&rft.aulast=Stein&rft.aufirst=KE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society of Clinical Pharmacology and Therapeutics, 117 West Ridge Pike, Suite 2, Conshohocken, PA 19428-1216, USA; phone: 610-825-3838; fax: 610-834-8652; email: ascpt@aol.com; URL: www.ascpt.org, Abstracts available. Price $20. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Apparent dose-dependent pharmacodynamics (PD) of nonsteroidal anti-inflammatory drug (NSAID) analgesia AN - 41557186; 2417536 AU - Dockens, R C AU - Harter, J G AU - Peck, C C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41557186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Apparent+dose-dependent+pharmacodynamics+%28PD%29+of+nonsteroidal+anti-inflammatory+drug+%28NSAID%29+analgesia&rft.au=Dockens%2C+R+C%3BHarter%2C+J+G%3BPeck%2C+C+C&rft.aulast=Dockens&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Ms. Elaine Galasso, 1718 Gallagher Road, Norristown, PA 19401-2800, USA. Telephone: (215) 825-3838. Fax: (215) 834-8652., Poster Paper No. PI-5 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Intracellular taurine content of alveolar pneumocytes AN - 41556215; 2373661 AU - Castranova, V AU - Porter, D W AU - Martin, W G AU - Banks, MA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41556215?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Intracellular+taurine+content+of+alveolar+pneumocytes&rft.au=Castranova%2C+V%3BPorter%2C+D+W%3BMartin%2C+W+G%3BBanks%2C+MA&rft.aulast=Castranova&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: APS Subscription, 9650 Rockville Pike, Bethesda, MD 20814, USA, The Physiologist, ISSN: 0031-9376, Vol 33, No 4, August 1990, abstracts: $25.00 & single issue $5.00; subscription: $25.00/yr in US & $35.00 elsewhere Paper No. 90.2 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Individualization of dose: Development of dosing recommendations based upon patient factor analysis, a worthy goal of drug development AN - 41556103; 2417541 AU - Peck, C C AU - Bashaw, D AU - Dockens, R AU - Harter, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41556103?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Individualization+of+dose%3A+Development+of+dosing+recommendations+based+upon+patient+factor+analysis%2C+a+worthy+goal+of+drug+development&rft.au=Peck%2C+C+C%3BBashaw%2C+D%3BDockens%2C+R%3BHarter%2C+J&rft.aulast=Peck&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Ms. Elaine Galasso, 1718 Gallagher Road, Norristown, PA 19401-2800, USA. Telephone: (215) 825-3838. Fax: (215) 834-8652., Poster Paper No. PI-6 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Apoptosis induction after silica inhalation in rats AN - 41552584; 3459385 AU - Suarez, F AU - Porter, D W AU - Mercer, R AU - Millecchia, L AU - Castranova, V AU - Ramsey, D AU - Khan, A AU - McLaurin, J L AU - Teass, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41552584?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Apoptosis+induction+after+silica+inhalation+in+rats&rft.au=Suarez%2C+F%3BPorter%2C+D+W%3BMercer%2C+R%3BMillecchia%2C+L%3BCastranova%2C+V%3BRamsey%2C+D%3BKhan%2C+A%3BMcLaurin%2C+J+L%3BTeass%2C+A&rft.aulast=Suarez&rft.aufirst=F&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, USA, Abstracts available. Price $50. Poster Paper No. 617 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - PK/PD consideration in renal and hepatic impairment studies: A regulatory perspective AN - 41552382; 3453990 AU - Mehta, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41552382?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=PK%2FPD+consideration+in+renal+and+hepatic+impairment+studies%3A+A+regulatory+perspective&rft.au=Mehta%2C+M&rft.aulast=Mehta&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society of Clinical Pharmacology and Therapeutics, 117 West Ridge Pike, Suite 2, Conshohocken, PA 19428-1216, USA; phone: 610-825-3838; fax: 610-834-8652; email: ascpt@aol.com; URL: www.ascpt.org, Abstracts available. Price $20. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Transforming activity of DNA sequences of HHV-6 (GD strain) isolated from a patient with chronic fatigue syndrome AN - 41547925; 2438943 AU - Wang, J AU - Luka, J AU - Razzaque, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41547925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Transforming+activity+of+DNA+sequences+of+HHV-6+%28GD+strain%29+isolated+from+a+patient+with+chronic+fatigue+syndrome&rft.au=Wang%2C+J%3BLuka%2C+J%3BRazzaque%2C+A&rft.aulast=Wang&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 7th Floor, 605 Third Avenue, New York, NY 10158, USA, Journal of Cellular Biochemistry; Supplement 15E, 1991; ISSN: 0730-2312 Poster Paper No. M 443 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - New issues in cancer risk assessment AN - 41542905; 3421591 AU - Gaylor, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:Biology KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41542905?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=New+issues+in+cancer+risk+assessment&rft.au=Gaylor%2C+D&rft.aulast=Gaylor&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: University of Arkansas for Medical Sciences (UAMS), Division of Toxicology, 4301 W. Markham Slot 638-I, Little Rock, AR 72205, USA, Abstracts available. Contact UAMS for price. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - LFA-3, CD44 and CD45: Physiologic triggers of human monocyte TNF and IL-1 release AN - 41533788; 2352459 AU - Webb, DSA AU - Shimizu, Y AU - Van Seventer, GA AU - Shaw, S AU - Gerrard, T L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41533788?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=LFA-3%2C+CD44+and+CD45%3A+Physiologic+triggers+of+human+monocyte+TNF+and+IL-1+release&rft.au=Webb%2C+DSA%3BShimizu%2C+Y%3BVan+Seventer%2C+GA%3BShaw%2C+S%3BGerrard%2C+T+L&rft.aulast=Webb&rft.aufirst=DSA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: John Wiley & Sons, Inc., Subscription Department, 7th floor, 605 Thrid Avenue, New York, NY 10158, USA, Journal of Leukocyte Biology, Supplement 1, 1990, ISSN: 0741-5400 Paper No. 66 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Botanic garden horticultural worker exposure to pesticides AN - 41527803; 2288928 AU - Crandall AU - Reh, C M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41527803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Botanic+garden+horticultural+worker+exposure+to+pesticides&rft.au=Crandall%3BReh%2C+C+M&rft.aulast=Crandall&rft.aufirst=&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 21 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Formaldehyde exposures resulting from the use of formaldehyde containing cabinet fumigants in the field of cosmetology AN - 41526007; 2298377 AU - Almauger, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41526007?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Formaldehyde+exposures+resulting+from+the+use+of+formaldehyde+containing+cabinet+fumigants+in+the+field+of+cosmetology&rft.au=Almauger%2C+D&rft.aulast=Almauger&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Method evaluation of NIOSH method for determining 4,4'-MDA in air and comparison to OSHA method 57 and NIOSH P&CAM 142 AN - 41525638; 2298023 AU - Boeniger, M AU - Neumeister, C AU - Verdi, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41525638?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Method+evaluation+of+NIOSH+method+for+determining+4%2C4%27-MDA+in+air+and+comparison+to+OSHA+method+57+and+NIOSH+P%26amp%3BCAM+142&rft.au=Boeniger%2C+M%3BNeumeister%2C+C%3BVerdi%2C+J&rft.aulast=Boeniger&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 251 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Microorganism contamination of HVAC humidification system - a case study AN - 41520567; 2297272 AU - Burkhart, JE AU - Stanevich, R AU - Kovak, B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41520567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Microorganism+contamination+of+HVAC+humidification+system+-+a+case+study&rft.au=Burkhart%2C+JE%3BStanevich%2C+R%3BKovak%2C+B&rft.aulast=Burkhart&rft.aufirst=JE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 120 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Characterization of exposures to fifteen substances or classes of substances in diesel-engine exhaust emissions found in three types of operations AN - 41519378; 2298380 AU - Blade, L M AU - Zaebst, D D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41519378?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Characterization+of+exposures+to+fifteen+substances+or+classes+of+substances+in+diesel-engine+exhaust+emissions+found+in+three+types+of+operations&rft.au=Blade%2C+L+M%3BZaebst%2C+D+D&rft.aulast=Blade&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Specificity of antibody response to group C meningococcal polysaccharide AN - 41519323; 2315089 AU - Arakere, G AU - Frasch, CE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41519323?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Specificity+of+antibody+response+to+group+C+meningococcal+polysaccharide&rft.au=Arakere%2C+G%3BFrasch%2C+CE&rft.aulast=Arakere&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Avenue, N.W., Washington, DC 20005, USA. Telephone: (202) 737-3600., Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Adriamycin exposure assessment study among health care personnel AN - 41518949; 2297436 AU - Stephenson, R L AU - Rice, CH AU - Dimos, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41518949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Adriamycin+exposure+assessment+study+among+health+care+personnel&rft.au=Stephenson%2C+R+L%3BRice%2C+CH%3BDimos%2C+J&rft.aulast=Stephenson&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=37&rft.isbn=&rft.btitle=&rft.title=Scandinavian+journal+of+work%2C+environment+%26+health&rft.issn=03553140&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 166 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Fiber aerosol penetration through respirator filter media AN - 41518807; 2297351 AU - Stevens, G A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41518807?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Fiber+aerosol+penetration+through+respirator+filter+media&rft.au=Stevens%2C+G+A&rft.aulast=Stevens&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 137 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Separation of aerosol change and relative humidity effects on the performance of respirator filters AN - 41516855; 2297354 AU - Stevens, G A AU - Moyer, E S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41516855?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Separation+of+aerosol+change+and+relative+humidity+effects+on+the+performance+of+respirator+filters&rft.au=Stevens%2C+G+A%3BMoyer%2C+E+S&rft.aulast=Stevens&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 138 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Implementation of an experimental design approach to exposure assessment AN - 41516597; 2298301 AU - Hornung, R W AU - Herrick, R F AU - Stewart, P A AU - Hayes, R AU - Blair, A AU - Feigley, CE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41516597?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Implementation+of+an+experimental+design+approach+to+exposure+assessment&rft.au=Hornung%2C+R+W%3BHerrick%2C+R+F%3BStewart%2C+P+A%3BHayes%2C+R%3BBlair%2C+A%3BFeigley%2C+CE&rft.aulast=Hornung&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 329 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Industrial hygiene characterization of carbon monoxide exposures of bridge and tunnel workers in NYC AN - 41516340; 2298185 AU - Ringenburg, V L AU - McCammon, C S AU - Stern, F B AU - Lee, ST Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41516340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Industrial+hygiene+characterization+of+carbon+monoxide+exposures+of+bridge+and+tunnel+workers+in+NYC&rft.au=Ringenburg%2C+V+L%3BMcCammon%2C+C+S%3BStern%2C+F+B%3BLee%2C+ST&rft.aulast=Ringenburg&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 290 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Selected antibodies to leukocyte common antigen (CD45) inhibit neutrophil chemotaxis to leukotriene B sub(4) AN - 41511882; 2284279 AU - Harvath, L AU - Balke, JA AU - Russell, A A AU - Skubitz, K M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41511882?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Selected+antibodies+to+leukocyte+common+antigen+%28CD45%29+inhibit+neutrophil+chemotaxis+to+leukotriene+B+sub%284%29&rft.au=Harvath%2C+L%3BBalke%2C+JA%3BRussell%2C+A+A%3BSkubitz%2C+K+M&rft.aulast=Harvath&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Conservation of the neutralization epitope of the V3 region of human immunodeficiency virus type 1 sub(MN) envelope protein in different countries AN - 41508747; 2312966 AU - Vujcic, L K AU - Carrow, E AU - Glass, W AU - Seamon, K AU - Quinn, T AU - Galvao, F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41508747?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Conservation+of+the+neutralization+epitope+of+the+V3+region+of+human+immunodeficiency+virus+type+1+sub%28MN%29+envelope+protein+in+different+countries&rft.au=Vujcic%2C+L+K%3BCarrow%2C+E%3BGlass%2C+W%3BSeamon%2C+K%3BQuinn%2C+T%3BGalvao%2C+F&rft.aulast=Vujcic&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Avenue, N.W., Washington, DC 20005, USA. Telephone: (202) 737-3600., Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Negative impact of granulocyte-macrophage colony-stimulating factor and interleukin-3 on the phagocytic capacity of monocytes AN - 41508535; 2313152 AU - Abrahamsen, T G AU - Mertins, S AU - Carter, C S AU - Rubin, M AU - Read, E J AU - Hoffman, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41508535?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Negative+impact+of+granulocyte-macrophage+colony-stimulating+factor+and+interleukin-3+on+the+phagocytic+capacity+of+monocytes&rft.au=Abrahamsen%2C+T+G%3BMertins%2C+S%3BCarter%2C+C+S%3BRubin%2C+M%3BRead%2C+E+J%3BHoffman%2C+T&rft.aulast=Abrahamsen&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1325 Massachusetts Avenue, N.W., Washington, DC 20005, USA. Telephone: (202) 737-3600., Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Survey of toxic gas detection system users in the semiconductor industry AN - 41507428; 2297110 AU - Sussell, AL AU - Zellers, E T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41507428?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Survey+of+toxic+gas+detection+system+users+in+the+semiconductor+industry&rft.au=Sussell%2C+AL%3BZellers%2C+E+T&rft.aulast=Sussell&rft.aufirst=AL&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Expression of FGF receptor in tumor cell lines AN - 41505683; 2293003 AU - Ruta, M AU - Neiger, N AU - King, C R AU - Epstein, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41505683?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Expression+of+FGF+receptor+in+tumor+cell+lines&rft.au=Ruta%2C+M%3BNeiger%2C+N%3BKing%2C+C+R%3BEpstein%2C+J&rft.aulast=Ruta&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Foundation for Advanced Cancer Studies N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Silica exposure in selected coal mines AN - 41505352; 2298389 AU - Kovak, B AU - Hearl, F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41505352?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Silica+exposure+in+selected+coal+mines&rft.au=Kovak%2C+B%3BHearl%2C+F&rft.aulast=Kovak&rft.aufirst=B&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - BRCA-1 haplotype determination in a breast cancer case-control study AN - 41499640; 3417269 AU - Weston, A AU - Soucek, P AU - Wolff AU - Morabia, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41499640?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=BRCA-1+haplotype+determination+in+a+breast+cancer+case-control+study&rft.au=Weston%2C+A%3BSoucek%2C+P%3BWolff%3BMorabia%2C+A&rft.aulast=Weston&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society of Human Genetics, 9650 Rockville Pike, Bethesda, MD 20814, USA; phone: (301) 571-1825; email: subscriptions@journals.uchicago.edu, Abstracts available. Price $41.25. Poster Paper No. 500 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Epstein-Barr virus infection occurs at a high percentage in human IgE producing B lymphocytes AN - 41497902; 3432756 AU - Rivera, CE AU - Mostowski, H AU - Max, EE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41497902?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Epstein-Barr+virus+infection+occurs+at+a+high+percentage+in+human+IgE+producing+B+lymphocytes&rft.au=Rivera%2C+CE%3BMostowski%2C+H%3BMax%2C+EE&rft.aulast=Rivera&rft.aufirst=CE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: W.B. Saunders Co., P.O. Box 628239, Orlando, FL 32862-8239, USA; phone: (800) 654-2452; fax: (800) 225-6030; email: wbspcs@harcourtbrave.com; URL: customerservice.wbsaunders.com, Abstracts available. Contact W.B. Saunders for price. Poster Paper No. 2236 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of morphine on lymphocyte activation pathways AN - 41492947; 2281610 AU - Taplits, M AU - Jessop, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41492947?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+morphine+on+lymphocyte+activation+pathways&rft.au=Taplits%2C+M%3BJessop%2C+J&rft.aulast=Taplits&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of IL-1 production by extracts of selected organic dusts AN - 41491294; 2272425 AU - Lewis, D M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41491294?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction+of+IL-1+production+by+extracts+of+selected+organic+dusts&rft.au=Lewis%2C+D+M&rft.aulast=Lewis&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Specificity of human anti-morphine antibodies in workers occupationally exposed to opiates at an ethical narcotics manufacturing facility AN - 41488985; 2278184 AU - Biagini, R E AU - Henningsen, G M AU - Klincewitcz, S L AU - Mackenzie, BA AU - Janney, MJ Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41488985?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Specificity+of+human+anti-morphine+antibodies+in+workers+occupationally+exposed+to+opiates+at+an+ethical+narcotics+manufacturing+facility&rft.au=Biagini%2C+R+E%3BHenningsen%2C+G+M%3BKlincewitcz%2C+S+L%3BMackenzie%2C+BA%3BJanney%2C+MJ&rft.aulast=Biagini&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of calcium on regulated secretion in a murine helper T cell clone AN - 41487901; 2281313 AU - Johnson, S AU - Hoffman, T AU - Taplits, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41487901?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+calcium+on+regulated+secretion+in+a+murine+helper+T+cell+clone&rft.au=Johnson%2C+S%3BHoffman%2C+T%3BTaplits%2C+M&rft.aulast=Johnson&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of dietary copper and tin on rat hepatocellular antioxidant protection AN - 41486403; 2226891 AU - Hathcock, J N AU - Reicks, M AU - Rader, JI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41486403?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+dietary+copper+and+tin+on+rat+hepatocellular+antioxidant+protection&rft.au=Hathcock%2C+J+N%3BReicks%2C+M%3BRader%2C+JI&rft.aulast=Hathcock&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mechanism of HIV-1 inactivation by recombinant CD4: Saturation of gp120 receptors is not required AN - 41483777; 2280586 AU - Berkower, I AU - Murphy, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41483777?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Mechanism+of+HIV-1+inactivation+by+recombinant+CD4%3A+Saturation+of+gp120+receptors+is+not+required&rft.au=Berkower%2C+I%3BMurphy%2C+D&rft.aulast=Berkower&rft.aufirst=I&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Paper No. 1864 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Professional activities and industrial distribution of occupational safety and health professionals in the 1980's AN - 41482850; 2297160 AU - Pedersen, D H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41482850?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Professional+activities+and+industrial+distribution+of+occupational+safety+and+health+professionals+in+the+1980%27s&rft.au=Pedersen%2C+D+H&rft.aulast=Pedersen&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of polyclonal B cell activation and (auto) antigen-specific stimulation in murine lupus AN - 41482505; 2284011 AU - Klinman, D M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41482505?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+polyclonal+B+cell+activation+and+%28auto%29+antigen-specific+stimulation+in+murine+lupus&rft.au=Klinman%2C+D+M&rft.aulast=Klinman&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Job exposure matrix for identification of exposures in occupational settings AN - 41481421; 2297394 AU - Sieber, WK Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41481421?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Job+exposure+matrix+for+identification+of+exposures+in+occupational+settings&rft.au=Sieber%2C+WK+Jr&rft.aulast=Sieber&rft.aufirst=WK&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 151 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Environmental evaluation of aerosols formed in dairy barns from the use of bedding choppers AN - 41481109; 2289276 AU - Piacitelli, LA AU - Olenchock, SA AU - Sorenson, W G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41481109?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Environmental+evaluation+of+aerosols+formed+in+dairy+barns+from+the+use+of+bedding+choppers&rft.au=Piacitelli%2C+LA%3BOlenchock%2C+SA%3BSorenson%2C+W+G&rft.aulast=Piacitelli&rft.aufirst=LA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Paper No. 61 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Selection of radiofrequency radiation control measures for dielectric heaters in the waterbed industry AN - 41480356; 2297977 AU - Murray, W E AU - Cox, C AU - Conover, D L AU - Edwards, R M AU - Werren, D M AU - Smith, J M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41480356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Selection+of+radiofrequency+radiation+control+measures+for+dielectric+heaters+in+the+waterbed+industry&rft.au=Murray%2C+W+E%3BCox%2C+C%3BConover%2C+D+L%3BEdwards%2C+R+M%3BWerren%2C+D+M%3BSmith%2C+J+M&rft.aulast=Murray&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Industrial Hygiene Association, 345 White Pond Drive, P.O. Box 8390, Akron, OH 44320, USA, Abstracts, $35.00 Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - FDA Modernization Act and its effect on defibrillator technology AN - 41473244; 3391538 AU - Callahan, T J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41473244?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=FDA+Modernization+Act+and+its+effect+on+defibrillator+technology&rft.au=Callahan%2C+T+J&rft.aulast=Callahan&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Association for Advancement of Medical Instrumentation, 3330 Washington Boulevard, Suite 400, Arlington, VA 22201-4598, USA, Abstracts available. Price $75. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Morphological effect of carotenoids in livers of choline-deficient rats AN - 41472146; 2255658 AU - Sheikh, N M AU - Jenkins, MY AU - Carter, C J AU - Mitchell, G V AU - Grundel, E AU - Blakely Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41472146?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Morphological+effect+of+carotenoids+in+livers+of+choline-deficient+rats&rft.au=Sheikh%2C+N+M%3BJenkins%2C+MY%3BCarter%2C+C+J%3BMitchell%2C+G+V%3BGrundel%2C+E%3BBlakely&rft.aulast=Sheikh&rft.aufirst=N&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of dietary carotenoids on biochemical changes in rats fed a choline-deficient diet AN - 41471146; 2255655 AU - Jenkins, MY AU - Mitchell, G V AU - Grundel, E AU - Blakely Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41471146?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+dietary+carotenoids+on+biochemical+changes+in+rats+fed+a+choline-deficient+diet&rft.au=Jenkins%2C+MY%3BMitchell%2C+G+V%3BGrundel%2C+E%3BBlakely&rft.aulast=Jenkins&rft.aufirst=MY&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tissue distribution and excretion of 14C-labeled cinnamic aldehyde following acute subacute oral administration in male Fischer-344 rats AN - 41466553; 2188810 AU - Sapienza, P P AU - Ikeda, G J AU - Warr, P I AU - Dailey, R E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41466553?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Tissue+distribution+and+excretion+of+14C-labeled+cinnamic+aldehyde+following+acute+subacute+oral+administration+in+male+Fischer-344+rats&rft.au=Sapienza%2C+P+P%3BIkeda%2C+G+J%3BWarr%2C+P+I%3BDailey%2C+R+E&rft.aulast=Sapienza&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th St., NW, Ste. 1100, Washington, DC 20005, USA. Telephone: 202-293-5935. Fax: 202-371-1090., Poster Paper No. 945 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Taurine does not attenuate isotretinoin toxicity in cultured organogenesis-staged rat embryos AN - 41456823; 2189657 AU - Flynn, T J AU - Gibson, R R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41456823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Taurine+does+not+attenuate+isotretinoin+toxicity+in+cultured+organogenesis-staged+rat+embryos&rft.au=Flynn%2C+T+J%3BGibson%2C+R+R&rft.aulast=Flynn&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th St., NW, Ste. 1100, Washington, DC 20005, USA. Telephone: 202-293-5935. Fax: 202-371-1090., Poster Paper No. 1098 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Inhibitory action of bisbenzylisoquinoline alkaloids on the phagocytotic potential of alveolar macrophages: Usefulness as a screen for antifibrotic potency AN - 41449568; 2189714 AU - Kang, J H AU - Ma, JKH AU - Ma, JYC AU - Malanga, C J AU - Mo, C G AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41449568?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Inhibitory+action+of+bisbenzylisoquinoline+alkaloids+on+the+phagocytotic+potential+of+alveolar+macrophages%3A+Usefulness+as+a+screen+for+antifibrotic+potency&rft.au=Kang%2C+J+H%3BMa%2C+JKH%3BMa%2C+JYC%3BMalanga%2C+C+J%3BMo%2C+C+G%3BCastranova%2C+V&rft.aulast=Kang&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th St., NW, Ste. 1100, Washington, DC 20005, USA. 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Fax: 202-371-1090., Poster Paper No. 1108 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - FDA'S perspective on human factors engineering AN - 41448503; 3391552 AU - Sawyer, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41448503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=FDA%27S+perspective+on+human+factors+engineering&rft.au=Sawyer%2C+D&rft.aulast=Sawyer&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Association for Advancement of Medical Instrumentation, 3330 Washington Boulevard, Suite 400, Arlington, VA 22201-4598, USA, Abstracts available. Price $75. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Influence of graded dietary levels of Spirulina maxima on vitamins A and E status of male rats AN - 41447060; 2255601 AU - Mitchell, G AU - Grundel, E AU - Jenkins, MY AU - Blakely Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41447060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Influence+of+graded+dietary+levels+of+Spirulina+maxima+on+vitamins+A+and+E+status+of+male+rats&rft.au=Mitchell%2C+G%3BGrundel%2C+E%3BJenkins%2C+MY%3BBlakely&rft.aulast=Mitchell&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - DNA strand breaks induced by freshly fractured silica: Possible role of hydroxyl radical AN - 41443294; 2186208 AU - Vallyathan, V AU - Dalal, N S AU - Shi, X AU - Nguyen, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41443294?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=DNA+strand+breaks+induced+by+freshly+fractured+silica%3A+Possible+role+of+hydroxyl+radical&rft.au=Vallyathan%2C+V%3BDalal%2C+N+S%3BShi%2C+X%3BNguyen%2C+M&rft.aulast=Vallyathan&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th St., NW, Ste. 1100, Washington, DC 20005, USA. 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Fax: 202-371-1090., Poster Paper No. 475 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of ornithine decarboxylase activity by 4,4'-methylene-bis(2-chloroaniline) (MOCA) in the rat AN - 41442074; 2187971 AU - Weigel, W W AU - Savage, RE Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41442074?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction+of+ornithine+decarboxylase+activity+by+4%2C4%27-methylene-bis%282-chloroaniline%29+%28MOCA%29+in+the+rat&rft.au=Weigel%2C+W+W%3BSavage%2C+RE+Jr&rft.aulast=Weigel&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1101 14th St., NW, Ste. 1100, Washington, DC 20005, USA. 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Fax: 202-371-1090., Poster Paper No. 760 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Lymphatic fatty acid and cholesterol absorption in wheat- or oat bran-fed rats AN - 41441263; 2232326 AU - Reicks, M AU - Satchithanandam, S AU - Calvert, R J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41441263?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Lymphatic+fatty+acid+and+cholesterol+absorption+in+wheat-+or+oat+bran-fed+rats&rft.au=Reicks%2C+M%3BSatchithanandam%2C+S%3BCalvert%2C+R+J&rft.aulast=Reicks&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Standards and the 1997 FDA Modernization Act (FDAMA) AN - 41434801; 3391462 AU - Furfine, C S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41434801?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Standards+and+the+1997+FDA+Modernization+Act+%28FDAMA%29&rft.au=Furfine%2C+C+S&rft.aulast=Furfine&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Association for Advancement of Medical Instrumentation, 3330 Washington Boulevard, Suite 400, Arlington, VA 22201-4598, USA, Abstracts available. Price $75. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - PKC- and IL-3 regulate actin cytoskeleton rearrangements associated with the effects on cell cycle by two distinct pathways: PKC-d dominates over IL-3 signal AN - 41434390; 3380953 AU - Romanova, L AU - Alexandrov, I AU - Nguyen, M AU - Nordan, R AU - Trepel, J AU - Mushinski, F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1500:Biochemistry KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41434390?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=PKC-+and+IL-3+regulate+actin+cytoskeleton+rearrangements+associated+with+the+effects+on+cell+cycle+by+two+distinct+pathways%3A+PKC-d+dominates+over+IL-3+signal&rft.au=Romanova%2C+L%3BAlexandrov%2C+I%3BNguyen%2C+M%3BNordan%2C+R%3BTrepel%2C+J%3BMushinski%2C+F&rft.aulast=Romanova&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Biochemistry and Molecular Biology, 9650 Rockville Pike, Bethesda, MD 20814-3996, USA; phone: (301) 530-7145; fax: (301) 571-1824; email: asbmb@asbmb.faseb.org; Contact ASBMB for abstract & price info. Poster Paper No. M 543 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Multiple resistance patterns of Salmonella isolates of veterinary origin AN - 41429539; 3365822 AU - Miller, MA AU - Fedorka-Cray, P J AU - Toelle, V AU - Hollinger, K AU - Tollefson, L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41429539?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Multiple+resistance+patterns+of+Salmonella+isolates+of+veterinary+origin&rft.au=Miller%2C+MA%3BFedorka-Cray%2C+P+J%3BToelle%2C+V%3BHollinger%2C+K%3BTollefson%2C+L&rft.aulast=Miller&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA; phone: (404) 639-3311; URL: http://www.cdc.gov, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of glutathione in MPP super(+) and HgCl sub(2) toxicity in PC-12 cells AN - 41427993; 3364146 AU - Duhart, H M AU - Hussain, S AU - Slikker, W Jr AU - Ali, S F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41427993?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+glutathione+in+MPP+super%28%2B%29+and+HgCl+sub%282%29+toxicity+in+PC-12+cells&rft.au=Duhart%2C+H+M%3BHussain%2C+S%3BSlikker%2C+W+Jr%3BAli%2C+S+F&rft.aulast=Duhart&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 1370 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - High-molecular-weight carrageenan induces dose-dependent alterations in colonic mucosal thymidine kinase activity AN - 41426305; 2113378 AU - Calvert, R J AU - Satchithanandam, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41426305?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=High-molecular-weight+carrageenan+induces+dose-dependent+alterations+in+colonic+mucosal+thymidine+kinase+activity&rft.au=Calvert%2C+R+J%3BSatchithanandam%2C+S&rft.aulast=Calvert&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Recent approaches to measuring target-tissue concentrations (c) in neurotoxicological studies AN - 41424939; 3363933 AU - Slikker, W Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41424939?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Recent+approaches+to+measuring+target-tissue+concentrations+%28c%29+in+neurotoxicological+studies&rft.au=Slikker%2C+W+Jr&rft.aulast=Slikker&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Production of interferon by alveolar macrophages and type II cells AN - 41422767; 2101252 AU - Castranova, V AU - Pailes, V H AU - Booth, JA AU - Hahon, N Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41422767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Production+of+interferon+by+alveolar+macrophages+and+type+II+cells&rft.au=Castranova%2C+V%3BPailes%2C+V+H%3BBooth%2C+JA%3BHahon%2C+N&rft.aulast=Castranova&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - IL-4 regulation of human anti-CD3 proliferative response AN - 41422741; 2099143 AU - Kozak, R W AU - Horohov, D W AU - Jones, L AU - Siegel, J P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41422741?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=IL-4+regulation+of+human+anti-CD3+proliferative+response&rft.au=Kozak%2C+R+W%3BHorohov%2C+D+W%3BJones%2C+L%3BSiegel%2C+J+P&rft.aulast=Kozak&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Exposure and hazard assessment of dioxins/furans via the consumption of dairy foods and fish AN - 41422600; 3364183 AU - Bolger, P M AU - Jensen, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41422600?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Exposure+and+hazard+assessment+of+dioxins%2Ffurans+via+the+consumption+of+dairy+foods+and+fish&rft.au=Bolger%2C+P+M%3BJensen%2C+E&rft.aulast=Bolger&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 1407 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Application of a commercially available in vitro stress gene assay as a rapid prescreen for compound selection to test specificity in the TG. AC mouse model AN - 41422500; 3364312 AU - Sistare, F D AU - Rosenzweig, BA AU - Hanig, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41422500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Application+of+a+commercially+available+in+vitro+stress+gene+assay+as+a+rapid+prescreen+for+compound+selection+to+test+specificity+in+the+TG.+AC+mouse+model&rft.au=Sistare%2C+F+D%3BRosenzweig%2C+BA%3BHanig%2C+J&rft.aulast=Sistare&rft.aufirst=F&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 1536 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Recovery of fish oil-derived fatty acids in lymph of thoracic duct-cannulated Wistar rats AN - 41419089; 2113617 AU - Morehouse, K M AU - Reicks, M AU - Hoadley, J AU - Satchithanandam, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41419089?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Recovery+of+fish+oil-derived+fatty+acids+in+lymph+of+thoracic+duct-cannulated+Wistar+rats&rft.au=Morehouse%2C+K+M%3BReicks%2C+M%3BHoadley%2C+J%3BSatchithanandam%2C+S&rft.aulast=Morehouse&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Immunization with monoclonal anti-idiotypic antibodies in vivo: Dramatic differences in potency AN - 41417754; 2106593 AU - Epstein, S L AU - Harvath, L AU - Reeves, J P AU - Rubinstein, L J AU - Misplon, JA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41417754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Immunization+with+monoclonal+anti-idiotypic+antibodies+in+vivo%3A+Dramatic+differences+in+potency&rft.au=Epstein%2C+S+L%3BHarvath%2C+L%3BReeves%2C+J+P%3BRubinstein%2C+L+J%3BMisplon%2C+JA&rft.aulast=Epstein&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Hydrogen peroxide alters energy metabolism in alveolar type II cells AN - 41417024; 2121268 AU - LaCagnin, L B AU - Bowman, L AU - Ma, JYC AU - Miles, PR Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41417024?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Hydrogen+peroxide+alters+energy+metabolism+in+alveolar+type+II+cells&rft.au=LaCagnin%2C+L+B%3BBowman%2C+L%3BMa%2C+JYC%3BMiles%2C+PR&rft.aulast=LaCagnin&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Vitamin and mineral supplement use among U.S. children 2-6 years of age AN - 41416917; 2108446 AU - Kim, I AU - Park, Y K AU - Moss, A AU - Yetley, E A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41416917?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Vitamin+and+mineral+supplement+use+among+U.S.+children+2-6+years+of+age&rft.au=Kim%2C+I%3BPark%2C+Y+K%3BMoss%2C+A%3BYetley%2C+E+A&rft.aulast=Kim&rft.aufirst=I&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Genomic instability and tumorigenic cell transformation in folate deficient Chinese hamster ovary cells AN - 41416743; 3363149 AU - Pogribna, M AU - Melnyk, S AU - Miller, B AU - Pogribny, I P AU - James, S J AU - Allaben, W T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41416743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Genomic+instability+and+tumorigenic+cell+transformation+in+folate+deficient+Chinese+hamster+ovary+cells&rft.au=Pogribna%2C+M%3BMelnyk%2C+S%3BMiller%2C+B%3BPogribny%2C+I+P%3BJames%2C+S+J%3BAllaben%2C+W+T&rft.aulast=Pogribna&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 376 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role for guanyl nucleotide-binding protein(s) in regulating inositol phospholipid hydrolysis in murine, helper T cell clones AN - 41415216; 2109679 AU - Bonvini, E AU - DeBell, KE AU - Hoffman, T AU - Taplits Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41415216?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+for+guanyl+nucleotide-binding+protein%28s%29+in+regulating+inositol+phospholipid+hydrolysis+in+murine%2C+helper+T+cell+clones&rft.au=Bonvini%2C+E%3BDeBell%2C+KE%3BHoffman%2C+T%3BTaplits&rft.aulast=Bonvini&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Efficacy of taurine and hypotaurine as hydroxyl radical scavengers AN - 41415215; 3363509 AU - Porter, D W AU - Shi, X AU - Leonard, S S AU - Vallyathan, V AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41415215?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Efficacy+of+taurine+and+hypotaurine+as+hydroxyl+radical+scavengers&rft.au=Porter%2C+D+W%3BShi%2C+X%3BLeonard%2C+S+S%3BVallyathan%2C+V%3BCastranova%2C+V&rft.aulast=Porter&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 736 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differential desensitization of muscarinic-stimulated PI hydrolysis and norepinephrine release in PC12 cells by dbcAMP AN - 41415156; 2125883 AU - Takashima, A AU - Kenimer, J G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41415156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Differential+desensitization+of+muscarinic-stimulated+PI+hydrolysis+and+norepinephrine+release+in+PC12+cells+by+dbcAMP&rft.au=Takashima%2C+A%3BKenimer%2C+J+G&rft.aulast=Takashima&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tumor necrosis factor a modulates transforming growth factor a expression following chemically-induced hepatotoxicity AN - 41414343; 3364111 AU - Gallucci, R M AU - Toriumi, W AU - Simeonova, P P AU - Luster, MI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41414343?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Tumor+necrosis+factor+a+modulates+transforming+growth+factor+a+expression+following+chemically-induced+hepatotoxicity&rft.au=Gallucci%2C+R+M%3BToriumi%2C+W%3BSimeonova%2C+P+P%3BLuster%2C+MI&rft.aulast=Gallucci&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 1335 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Immunochemical characterization of group 19 pneumolysins and molecular cloning of 19F pneumolysin genes AN - 41414051; 2127479 AU - Li, J P AU - Goldman, N D AU - Li, S P AU - Lee, C-J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41414051?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Immunochemical+characterization+of+group+19+pneumolysins+and+molecular+cloning+of+19F+pneumolysin+genes&rft.au=Li%2C+J+P%3BGoldman%2C+N+D%3BLi%2C+S+P%3BLee%2C+C-J&rft.aulast=Li&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Application of in vitro drug metabolism information to drug development and product labeling: An FDA perspective AN - 41413929; 3377571 AU - Honig, P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41413929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Application+of+in+vitro+drug+metabolism+information+to+drug+development+and+product+labeling%3A+An+FDA+perspective&rft.au=Honig%2C+P&rft.aulast=Honig&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800, USA; phone: (610) 825-3838; fax: (610) 834-8652; email: ASCPT@aol.com; URL: http://www.ascpt.org, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - IND regulatory initiatives at FDA AN - 41413814; 3377509 AU - Lumpkin, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41413814?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=IND+regulatory+initiatives+at+FDA&rft.au=Lumpkin%2C+M&rft.aulast=Lumpkin&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800, USA; phone: (610) 825-3838; fax: (610) 834-8652; email: ASCPT@aol.com; URL: http://www.ascpt.org, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cis-acting regulatory sequences within a conserved intron of the segmentation gene engrailed (en) AN - 41412411; 2099207 AU - Kassis, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41412411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Cis-acting+regulatory+sequences+within+a+conserved+intron+of+the+segmentation+gene+engrailed+%28en%29&rft.au=Kassis%2C+J&rft.aulast=Kassis&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Genetics Society of America, Administrative Office, 9650 Rockville Pike, Bethesda, MD 20814 (USA). N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Neuroimmune interactions and interleukin 2 release AN - 41408431; 2104386 AU - Jessop, J J AU - Braxton, J AU - Sobotka, T J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41408431?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Neuroimmune+interactions+and+interleukin+2+release&rft.au=Jessop%2C+J+J%3BBraxton%2C+J%3BSobotka%2C+T+J&rft.aulast=Jessop&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Inflammatory mediators in cadmium-induced nephrotoxicity AN - 41407060; 3364371 AU - Matheson, J M AU - Luster, MI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41407060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Inflammatory+mediators+in+cadmium-induced+nephrotoxicity&rft.au=Matheson%2C+J+M%3BLuster%2C+MI&rft.aulast=Matheson&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 1595 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Beta interferon gene alleles correlate with serum IFN in goats; caseous lymphadenitis high in low IFN breed AN - 41406560; 2103747 AU - Gainer, J AU - Silverberg, A AU - Bradbury, R AU - Long-Bradley, P AU - Womack, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41406560?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Beta+interferon+gene+alleles+correlate+with+serum+IFN+in+goats%3B+caseous+lymphadenitis+high+in+low+IFN+breed&rft.au=Gainer%2C+J%3BSilverberg%2C+A%3BBradbury%2C+R%3BLong-Bradley%2C+P%3BWomack%2C+J&rft.aulast=Gainer&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Young deaths with silicosis: Characteristics from national mortality data AN - 41406307; 3351966 AU - Roberts, S S AU - Castellan, R M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41406307?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Young+deaths+with+silicosis%3A+Characteristics+from+national+mortality+data&rft.au=Roberts%2C+S+S%3BCastellan%2C+R+M&rft.aulast=Roberts&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Public Health Association, Department C, P.O. Box 753, Waldorf, MD 20604-0753, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In vitro percutaneous absorption of a hydrophobic compound through viable hairless guinea pig skin AN - 41404538; 2080538 AU - Bronaugh, R L AU - Collier, S W AU - Stewart, R F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41404538?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=In+vitro+percutaneous+absorption+of+a+hydrophobic+compound+through+viable+hairless+guinea+pig+skin&rft.au=Bronaugh%2C+R+L%3BCollier%2C+S+W%3BStewart%2C+R+F&rft.aulast=Bronaugh&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1133 Fifteenth Street, NW, Suite 1000, Washington, DC 20005 (USA), Price: $ 20.00 + $ 3.00 for postage and handling Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Meta-analysis of the Iraqi and seychelles methylmercury studies AN - 41402926; 3362940 AU - Carrington, C D AU - Bolger, P M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41402926?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Meta-analysis+of+the+Iraqi+and+seychelles+methylmercury+studies&rft.au=Carrington%2C+C+D%3BBolger%2C+P+M&rft.aulast=Carrington&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 164 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Exposure to diesel exhaust particles (DEP) alters the responsiveness of rats to bacterial lipopolysaccharide (LPS) insults AN - 41400685; 3364773 AU - Yang, H-M AU - Ma, JYC AU - Castranova, V AU - Barger, M W AU - Ma, JKH Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41400685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Exposure+to+diesel+exhaust+particles+%28DEP%29+alters+the+responsiveness+of+rats+to+bacterial+lipopolysaccharide+%28LPS%29+insults&rft.au=Yang%2C+H-M%3BMa%2C+JYC%3BCastranova%2C+V%3BBarger%2C+M+W%3BMa%2C+JKH&rft.aulast=Yang&rft.aufirst=H-M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 1996 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Representation and diversity: A Self-Assessment Module (SAM) for Ryan White CARE Act Planning Councils and Consortia AN - 41398073; 3351733 AU - Powell, A AU - Young, S AU - Conviser, R AU - Gomez, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41398073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Representation+and+diversity%3A+A+Self-Assessment+Module+%28SAM%29+for+Ryan+White+CARE+Act+Planning+Councils+and+Consortia&rft.au=Powell%2C+A%3BYoung%2C+S%3BConviser%2C+R%3BGomez%2C+M&rft.aulast=Powell&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Public Health Association, Department C, P.O. Box 753, Waldorf, MD 20604-0753, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of a colorimetric sensor strip to detect decomposition in frozen seafood AN - 41396670; 3367418 AU - Miller, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2500:Chemistry and Chemical Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41396670?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+additives+and+contaminants&rft.atitle=Liquid+chromatographic+method+for+fumonisin+B1+in+sorghum+syrup+and+corn-based+breakfast+cereals.&rft.au=Trucksess%2C+M+W%3BCho%2C+T+H%3BReady%2C+D+E&rft.aulast=Trucksess&rft.aufirst=M&rft.date=2000-02-01&rft.volume=17&rft.issue=2&rft.spage=161&rft.isbn=&rft.btitle=&rft.title=Food+additives+and+contaminants&rft.issn=0265203X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: PITTCON '98, 300 Penn Center Boulevard, Suite 332, Pittsburgh, PA 15235-5503, USA, Abstracts available. Price $10 (USA); $12 (Outside USA). Poster Paper No. 1717P N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Responding to the needs of women with HIV: Title I and II of the Ryan White CARE Act - A report on progress from the field AN - 41396617; 3353225 AU - Eichler, A AU - Marconi, K AU - Lopez, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41396617?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Responding+to+the+needs+of+women+with+HIV%3A+Title+I+and+II+of+the+Ryan+White+CARE+Act+-+A+report+on+progress+from+the+field&rft.au=Eichler%2C+A%3BMarconi%2C+K%3BLopez%2C+C&rft.aulast=Eichler&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Public Health Association, Department C, P.O. Box 753, Waldorf, MD 20604-0753, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative acute toxicity of three glycol ethers in rodents exposed via drinking water AN - 41395038; 2082093 AU - Henningsen, G M AU - Sendelbach, LE AU - Braun, A G AU - Goad, MEP Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41395038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparative+acute+toxicity+of+three+glycol+ethers+in+rodents+exposed+via+drinking+water&rft.au=Henningsen%2C+G+M%3BSendelbach%2C+LE%3BBraun%2C+A+G%3BGoad%2C+MEP&rft.aulast=Henningsen&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1133 Fifteenth Street, NW, Suite 1000, Washington, DC 20005 (USA), Price: $ 20.00 + $ 3.00 for postage and handling Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Intestinal absorption and lipoprotein transport of (n-3) docosahexaenoic acid AN - 41394760; 2113625 AU - Chen, I S AU - Satchithanandam, S AU - Irausquin, H AU - Sheppard, A J AU - Calvert, R J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41394760?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Intestinal+absorption+and+lipoprotein+transport+of+%28n-3%29+docosahexaenoic+acid&rft.au=Chen%2C+I+S%3BSatchithanandam%2C+S%3BIrausquin%2C+H%3BSheppard%2C+A+J%3BCalvert%2C+R+J&rft.aulast=Chen&rft.aufirst=I&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of dietary vitamin E on vitamin E utilization in rats fed casein and algal proteins AN - 41392792; 2108878 AU - Grundel, E AU - Mitchell, G V AU - Jenkins, MY Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41392792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+dietary+vitamin+E+on+vitamin+E+utilization+in+rats+fed+casein+and+algal+proteins&rft.au=Grundel%2C+E%3BMitchell%2C+G+V%3BJenkins%2C+MY&rft.aulast=Grundel&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sugar alcohols health claims - FDA case report AN - 41392736; 3371568 AU - Saltsman, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41392736?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Sugar+alcohols+health+claims+-+FDA+case+report&rft.au=Saltsman%2C+J&rft.aulast=Saltsman&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: International Association of Dental Research (IADR), 1619 Duke Street, Alexandria, VA 22314, USA; fax: (703) 548-1883, Abstracts available. Price $30. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluating the safety of varicella virus vaccine AN - 41391933; 3350338 AU - Salive, ME AU - Wise, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41391933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Evaluating+the+safety+of+varicella+virus+vaccine&rft.au=Salive%2C+ME%3BWise%2C+R&rft.aulast=Salive&rft.aufirst=ME&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Public Health Association, Department C, P.O. Box 753, Waldorf, MD 20604-0753, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of the TNF-receptors (TNFR) in carbon tetrachloride-induced liver toxicity AN - 41391871; 3364110 AU - Simeonova, P P AU - Flood, L AU - Kommineni, C AU - Luster, MI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41391871?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+the+TNF-receptors+%28TNFR%29+in+carbon+tetrachloride-induced+liver+toxicity&rft.au=Simeonova%2C+P+P%3BFlood%2C+L%3BKommineni%2C+C%3BLuster%2C+MI&rft.aulast=Simeonova&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 1334 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - LC analysis of retinyl palmiters, all-rac-a-tocopheryl acetate and tocopherols in infant formula using matrix solid phase dispersion extraction AN - 41389740; 3367416 AU - Chase, GW Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2500:Chemistry and Chemical Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41389740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=LC+analysis+of+retinyl+palmiters%2C+all-rac-a-tocopheryl+acetate+and+tocopherols+in+infant+formula+using+matrix+solid+phase+dispersion+extraction&rft.au=Chase%2C+GW+Jr&rft.aulast=Chase&rft.aufirst=GW&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: PITTCON '98, 300 Penn Center Boulevard, Suite 332, Pittsburgh, PA 15235-5503, USA, Abstracts available. Price $10 (USA); $12 (Outside USA). Poster Paper No. 1715P N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - T cell conjugation with beads coated with the anti-T cell receptor antibody, 2C11-145, represents a functional T cell response AN - 41388901; 2109689 AU - DeBell, KE AU - Taplits AU - Hoffman, T AU - Bonvini, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41388901?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=T+cell+conjugation+with+beads+coated+with+the+anti-T+cell+receptor+antibody%2C+2C11-145%2C+represents+a+functional+T+cell+response&rft.au=DeBell%2C+KE%3BTaplits%3BHoffman%2C+T%3BBonvini%2C+E&rft.aulast=DeBell&rft.aufirst=KE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identification of kinesin from platelets AN - 41388277; 2060929 AU - Vargo, SA AU - Mullins, J M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41388277?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Identification+of+kinesin+from+platelets&rft.au=Vargo%2C+SA%3BMullins%2C+J+M&rft.aulast=Vargo&rft.aufirst=SA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Neurotoxicological and behavioral assessment of 2',3'-dideoxycytidine (DDC) and thalidomide (THAL) in rhesus monkeys AN - 41386245; 3362943 AU - Patterson, T A AU - Zielinski, W L AU - Reepmeyer, J C AU - Nickols, J AU - Paule, M G AU - Slikker, W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41386245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Neurotoxicological+and+behavioral+assessment+of+2%27%2C3%27-dideoxycytidine+%28DDC%29+and+thalidomide+%28THAL%29+in+rhesus+monkeys&rft.au=Patterson%2C+T+A%3BZielinski%2C+W+L%3BReepmeyer%2C+J+C%3BNickols%2C+J%3BPaule%2C+M+G%3BSlikker%2C+W&rft.aulast=Patterson&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 167 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dermal exposure assessment for the fragrance musk xylol AN - 41384990; 3363047 AU - Bronaugh, R L AU - Yourick, J J AU - Havery, DC Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41384990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Dermal+exposure+assessment+for+the+fragrance+musk+xylol&rft.au=Bronaugh%2C+R+L%3BYourick%2C+J+J%3BHavery%2C+DC&rft.aulast=Bronaugh&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA, Abstracts available. Price $45. Poster Paper No. 274 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Tissue retinol, alpha -tocopherol and thiobarbituric acid reactive substances levels in rats fed varied protein and vitamin A sources AN - 41383534; 2098822 AU - Jenkins, MY AU - Mitchell, G V AU - Grundel, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41383534?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Tissue+retinol%2C+alpha+-tocopherol+and+thiobarbituric+acid+reactive+substances+levels+in+rats+fed+varied+protein+and+vitamin+A+sources&rft.au=Jenkins%2C+MY%3BMitchell%2C+G+V%3BGrundel%2C+E&rft.aulast=Jenkins&rft.aufirst=MY&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Design and conduct of ADHD drug treatment trials: Regulatory considerations AN - 41381227; 3348636 AU - Laughren, T P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41381227?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Design+and+conduct+of+ADHD+drug+treatment+trials%3A+Regulatory+considerations&rft.au=Laughren%2C+T+P&rft.aulast=Laughren&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: AACAP--Publications Department, 3615 Wisconsin Avenue, NW, Washington, DC 20016, Abstracts available. Price $20. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Frequent rest breaks and musculoskeletal discomfort in keyboard intensive work: Preliminary results of a worksite intervention AN - 41375597; 3342542 AU - Conway, F T AU - Sauter, S L AU - Swanson, NG AU - Galinsky, T L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41375597?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Frequent+rest+breaks+and+musculoskeletal+discomfort+in+keyboard+intensive+work%3A+Preliminary+results+of+a+worksite+intervention&rft.au=Conway%2C+F+T%3BSauter%2C+S+L%3BSwanson%2C+NG%3BGalinsky%2C+T+L&rft.aulast=Conway&rft.aufirst=F&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Human Factors and Ergonomics Society, PO Box 1369, Santa Monica, CA 90406-1369, Abstracts and selected full papers available. Price $70 plus shipping. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Conducting a needs assessment: A self-assessment module for Ryan White CARE Act Planning Councils and Consortia AN - 41374244; 3351734 AU - Young, S AU - Powell, A AU - Conviser, R AU - Gomez, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41374244?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Conducting+a+needs+assessment%3A+A+self-assessment+module+for+Ryan+White+CARE+Act+Planning+Councils+and+Consortia&rft.au=Young%2C+S%3BPowell%2C+A%3BConviser%2C+R%3BGomez%2C+M&rft.aulast=Young&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Public Health Association, Department C, P.O. Box 753, Waldorf, MD 20604-0753, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Behavioral assessment of rats fed a high-carbohydrate/low-protein meal AN - 41369553; 2098563 AU - Sobotka, T AU - Brodie, R AU - Quander, Y AU - Whiteman, A AU - Kopral, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41369553?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Behavioral+assessment+of+rats+fed+a+high-carbohydrate%2Flow-protein+meal&rft.au=Sobotka%2C+T%3BBrodie%2C+R%3BQuander%2C+Y%3BWhiteman%2C+A%3BKopral%2C+C&rft.aulast=Sobotka&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA). Telephone: (301) 530-7020, Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Epilogue and questions and answers AN - 41363730; 2008294 AU - Gorham, J R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41363730?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Epilogue+and+questions+and+answers&rft.au=Gorham%2C+J+R&rft.aulast=Gorham&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Conference proceedings will not be published N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of botulinum type A toxin neutralization on synaptosomal release of ( super(3)H)ACh AN - 41356606; 2062929 AU - Powers, L AU - Higgins, W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41356606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+botulinum+type+A+toxin+neutralization+on+synaptosomal+release+of+%28+super%283%29H%29ACh&rft.au=Powers%2C+L%3BHiggins%2C+W&rft.aulast=Powers&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: ASCB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Impact of changing health care delivery and payor systems on Ryan White Title II grants to states AN - 41347531; 3352227 AU - Young, S AU - McCarthy, S AU - Nelson, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41347531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Impact+of+changing+health+care+delivery+and+payor+systems+on+Ryan+White+Title+II+grants+to+states&rft.au=Young%2C+S%3BMcCarthy%2C+S%3BNelson%2C+J&rft.aulast=Young&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Public Health Association, Department C, P.O. Box 753, Waldorf, MD 20604-0753, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - FDA review of magnetic pulse devices for natural stimulation AN - 41346911; 2004786 AU - Frost, K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4000:ELECTRICAL ENGINEERING KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41346911?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=FDA+review+of+magnetic+pulse+devices+for+natural+stimulation&rft.au=Frost%2C+K&rft.aulast=Frost&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: IEEE Service Center, 445 Hoes Lane, Piscataway, NJ 08854 (USA), IEEE Catalog NO.: 88CH2566-8. Library of Congress Catalog Card No.: 88-80177. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Environmental assessments for animal drug products AN - 41327658; 3327632 AU - Miller, MA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 7500:Pharmacology KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41327658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Environmental+assessments+for+animal+drug+products&rft.au=Miller%2C+MA&rft.aulast=Miller&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Professor Arturo Anadon, Department of Toxicology and Pharmacology, Faculty of Veterinary Medicine, Universidad Computense de Madrid, 28040 Madrid, Spain, Abstracts available. Price L25. Paper No. PLEN5 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Inactivation of Clostridium botulinum type E spores by high pressure processing AN - 41321281; 3319954 AU - Reddy, N R AU - Solomon, H M AU - Rhodehamel, E J AU - Balasubramaniam, V M AU - Fingerhut, G A AU - Palaniappan, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41321281?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Inactivation+of+Clostridium+botulinum+type+E+spores+by+high+pressure+processing&rft.au=Reddy%2C+N+R%3BSolomon%2C+H+M%3BRhodehamel%2C+E+J%3BBalasubramaniam%2C+V+M%3BFingerhut%2C+G+A%3BPalaniappan%2C+S&rft.aulast=Reddy&rft.aufirst=N&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Institute of Food Technologists, 221 N. LaSalle Street, Suite 300, Chicago, IL 60601, Abstracts available. Price $25 within U.S., $50 elsewhere. Paper No. 20-1 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - 3-Nitropropionic acid (3-NPA) produces hypothermia and inhibits histochemical labeling of succinate dehydrogenase (SDH) in rat brain AN - 41316393; 3302404 AU - Scallet, A C AU - Nony, P AU - Rountree, R L AU - Ye, X AU - Binienda, Z Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41316393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=3-Nitropropionic+acid+%283-NPA%29+produces+hypothermia+and+inhibits+histochemical+labeling+of+succinate+dehydrogenase+%28SDH%29+in+rat+brain&rft.au=Scallet%2C+A+C%3BNony%2C+P%3BRountree%2C+R+L%3BYe%2C+X%3BBinienda%2C+Z&rft.aulast=Scallet&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, Attn: Nell Dillard, Abstracts available. Price $55. Poster Paper No. 79 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Baywatch - Surveillance of microbiological quality of Wellington beaches - An exercise in risk management and risk communication AN - 41314000; 3336144 AU - Palmer, S G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 5500:Geoscience KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41314000?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Baywatch+-+Surveillance+of+microbiological+quality+of+Wellington+beaches+-+An+exercise+in+risk+management+and+risk+communication&rft.au=Palmer%2C+S+G&rft.aulast=Palmer&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: New Zealand Water and Waste Association, PO Box 15974, New Lynn, Auckland, New Zealand, Full papers available. Price $50. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Lead exposure causes altered spermiogenesis in rabbits AN - 41313627; 3304147 AU - Sharpnack, D AU - Childress, C AU - Moorman, W AU - Schrader, S AU - Chapin, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41313627?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Lead+exposure+causes+altered+spermiogenesis+in+rabbits&rft.au=Sharpnack%2C+D%3BChildress%2C+C%3BMoorman%2C+W%3BSchrader%2C+S%3BChapin%2C+R&rft.aulast=Sharpnack&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, Attn: Nell Dillard, Abstracts available. Price $55. Poster Paper No. 1826 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Two-dimensional electrophoretic analysis of myocardial proteins from lead-exposed rabbits AN - 41310154; 3303267 AU - Toraason, M AU - Moorman, W AU - Mathias, P I AU - Futz, C AU - Witzmann, F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41310154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Two-dimensional+electrophoretic+analysis+of+myocardial+proteins+from+lead-exposed+rabbits&rft.au=Toraason%2C+M%3BMoorman%2C+W%3BMathias%2C+P+I%3BFutz%2C+C%3BWitzmann%2C+F&rft.aulast=Toraason&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, Attn: Nell Dillard, Abstracts available. Price $55. Poster Paper No. 945 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Risk assessment for aflatoxin in corn and peanuts in the United States AN - 41308839; 3303199 AU - Henry, SH AU - Dinovi, MJ AU - Bowers, J C AU - Bolger, P M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41308839?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Risk+assessment+for+aflatoxin+in+corn+and+peanuts+in+the+United+States&rft.au=Henry%2C+SH%3BDinovi%2C+MJ%3BBowers%2C+J+C%3BBolger%2C+P+M&rft.aulast=Henry&rft.aufirst=SH&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, Attn: Nell Dillard, Abstracts available. Price $55. Poster Paper No. 877 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Polystyrene (PS) and polymethylmethacrylate (PMMA) particles in the mouse: Effect of particle size and composition on deposition following IP injection AN - 41308065; 3303325 AU - Umbreit, TH AU - Tomazic, V J AU - Merritt, K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41308065?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Polystyrene+%28PS%29+and+polymethylmethacrylate+%28PMMA%29+particles+in+the+mouse%3A+Effect+of+particle+size+and+composition+on+deposition+following+IP+injection&rft.au=Umbreit%2C+TH%3BTomazic%2C+V+J%3BMerritt%2C+K&rft.aulast=Umbreit&rft.aufirst=TH&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, Attn: Nell Dillard, Abstracts available. Price $55. Poster Paper No. 1003 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mercuric chloride induces apoptosis in cultured mouse lymphoma (L5178Y-R) cells AN - 41307511; 3302520 AU - Goering, P L AU - Lucas, AD AU - Thomas, D AU - Dalton, T AU - Rojko, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41307511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Mercuric+chloride+induces+apoptosis+in+cultured+mouse+lymphoma+%28L5178Y-R%29+cells&rft.au=Goering%2C+P+L%3BLucas%2C+AD%3BThomas%2C+D%3BDalton%2C+T%3BRojko%2C+J&rft.aulast=Goering&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, Attn: Nell Dillard, Abstracts available. Price $55. Poster Paper No. 196 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Developmental toxicity of L-phenyl-alanine in intact Drosophila AN - 41306177; 3303646 AU - Lynch, D W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41306177?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Developmental+toxicity+of+L-phenyl-alanine+in+intact+Drosophila&rft.au=Lynch%2C+D+W&rft.aulast=Lynch&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190, Attn: Nell Dillard, Abstracts available. Price $55. Poster Paper No. 1325 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Survey of clinical pharmacology and biopharmaceutics studies submitted in new drug applications during the period of October 1994 to September 1995 AN - 41299523; 3301471 AU - Methta, MU AU - Lesko, L J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41299523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Survey+of+clinical+pharmacology+and+biopharmaceutics+studies+submitted+in+new+drug+applications+during+the+period+of+October+1994+to+September+1995&rft.au=Methta%2C+MU%3BLesko%2C+L+J&rft.aulast=Methta&rft.aufirst=MU&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Long-term abstinence in users of over the counter nicotine replacement AN - 41297368; 3301567 AU - Winchell, C J AU - Wright, C AU - Burke, L AU - Kramer, ED AU - Longmire, A W AU - Scheinbaum, M L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41297368?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Long-term+abstinence+in+users+of+over+the+counter+nicotine+replacement&rft.au=Winchell%2C+C+J%3BWright%2C+C%3BBurke%2C+L%3BKramer%2C+ED%3BLongmire%2C+A+W%3BScheinbaum%2C+M+L&rft.aulast=Winchell&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - PK-PD studies in new drug development: An FDA perspective AN - 41294606; 3301465 AU - Gillespie, W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41294606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=PK-PD+studies+in+new+drug+development%3A+An+FDA+perspective&rft.au=Gillespie%2C+W&rft.aulast=Gillespie&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Nicotine replacement and myocardial infarction AN - 41294003; 3301565 AU - Kramer, ED AU - Longmire, A W AU - Ma, Z J AU - Winchell, C J AU - Wright, C AU - Scheinbaum, M L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41294003?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Nicotine+replacement+and+myocardial+infarction&rft.au=Kramer%2C+ED%3BLongmire%2C+A+W%3BMa%2C+Z+J%3BWinchell%2C+C+J%3BWright%2C+C%3BScheinbaum%2C+M+L&rft.aulast=Kramer&rft.aufirst=ED&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Electromagnetic compatibility test protocols for alternative temperature measurement devices AN - 41288970; 3320216 AU - Larkin, J W AU - Balasubramaniam, V M AU - Chandru, S AU - Stringer, L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41288970?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Electromagnetic+compatibility+test+protocols+for+alternative+temperature+measurement+devices&rft.au=Larkin%2C+J+W%3BBalasubramaniam%2C+V+M%3BChandru%2C+S%3BStringer%2C+L&rft.aulast=Larkin&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Institute of Food Technologists, 221 N. LaSalle Street, Suite 300, Chicago, IL 60601, Abstracts available. Price $25 within U.S., $50 elsewhere. Paper No. 35B-14 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assessment of clinical pharmacology information in drug labeling AN - 41274632; 3301470 AU - Spyker, DA AU - Harvey, ED AU - Harvey, B E AU - Harvey, A M AU - Rumack, B H AU - Peck, C C AU - Atkinson, A J AU - Woosley, R L AU - Abernethy AU - Cantilena, L R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41274632?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Assessment+of+clinical+pharmacology+information+in+drug+labeling&rft.au=Spyker%2C+DA%3BHarvey%2C+ED%3BHarvey%2C+B+E%3BHarvey%2C+A+M%3BRumack%2C+B+H%3BPeck%2C+C+C%3BAtkinson%2C+A+J%3BWoosley%2C+R+L%3BAbernethy%3BCantilena%2C+L+R&rft.aulast=Spyker&rft.aufirst=DA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - New research and policy initiatives in CDER's Office of Clinical Pharmacology and Biopharmaceutics AN - 41258125; 3301458 AU - Lesko, L J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41258125?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=New+research+and+policy+initiatives+in+CDER%27s+Office+of+Clinical+Pharmacology+and+Biopharmaceutics&rft.au=Lesko%2C+L+J&rft.aulast=Lesko&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Silicon-oxygen radicals and their role in acute silicosis AN - 41252360; 1727457 AU - Vallyathan, V AU - Shi, X AU - Dalal, N S AU - Irr, W AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41252360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Silicon-oxygen+radicals+and+their+role+in+acute+silicosis&rft.au=Vallyathan%2C+V%3BShi%2C+X%3BDalal%2C+N+S%3BIrr%2C+W%3BCastranova%2C+V&rft.aulast=Vallyathan&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Lung Association, 1740 Broadway, New York, NY 10019 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - New food safety initiatives in CVM/FDA AN - 41247124; 1800354 AU - Fitzpatrick, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41247124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=New+food+safety+initiatives+in+CVM%2FFDA&rft.au=Fitzpatrick%2C+S&rft.aulast=Fitzpatrick&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society of Animal Science, 309 West Clark Street, Champaign, IL 61820 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dietary carbohydrate source and cellulose affect tissue trace minerals in weanling rats AN - 41245337; 1738450 AU - Rader, JI AU - Hight, S C AU - Capar, S G AU - Fox Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41245337?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Dietary+carbohydrate+source+and+cellulose+affect+tissue+trace+minerals+in+weanling+rats&rft.au=Rader%2C+JI%3BHight%2C+S+C%3BCapar%2C+S+G%3BFox&rft.aulast=Rader&rft.aufirst=JI&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mercuric chloride-induced abortion in immune sensitive and resistant strains of rats AN - 41244036; 1745797 AU - Alleva AU - Joseph, X AU - Balazs, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41244036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Mercuric+chloride-induced+abortion+in+immune+sensitive+and+resistant+strains+of+rats&rft.au=Alleva%3BJoseph%2C+X%3BBalazs%2C+T&rft.aulast=Alleva&rft.aufirst=&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Hyperalgesia and the histamine receptor AN - 41243194; 1756352 AU - Hanig, J P AU - Daugherty, SA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41243194?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Hyperalgesia+and+the+histamine+receptor&rft.au=Hanig%2C+J+P%3BDaugherty%2C+SA&rft.aulast=Hanig&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of iron-fortified bread on hematologic status of premenopausal women in Poland AN - 41235310; 1737663 AU - Kim, I AU - Lewis, C J AU - Crane, N T AU - Rafalski, H AU - Yetley, E A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41235310?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+iron-fortified+bread+on+hematologic+status+of+premenopausal+women+in+Poland&rft.au=Kim%2C+I%3BLewis%2C+C+J%3BCrane%2C+N+T%3BRafalski%2C+H%3BYetley%2C+E+A&rft.aulast=Kim&rft.aufirst=I&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Rapid induction of ODC activity after rats given soybean trypsin inhibitor with single meal or by gavage AN - 41230852; 1744605 AU - Geyer, S J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41230852?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Rapid+induction+of+ODC+activity+after+rats+given+soybean+trypsin+inhibitor+with+single+meal+or+by+gavage&rft.au=Geyer%2C+S+J&rft.aulast=Geyer&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Inositol phospholipid hydrolysis by stimulation of T-cell antigen receptor complex in antigen-specific, murine T cell clones AN - 41229860; 1764697 AU - Bonvini, E AU - Hodes, R AU - DeBell, K AU - Hoffman, T AU - Taplits, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41229860?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Inositol+phospholipid+hydrolysis+by+stimulation+of+T-cell+antigen+receptor+complex+in+antigen-specific%2C+murine+T+cell+clones&rft.au=Bonvini%2C+E%3BHodes%2C+R%3BDeBell%2C+K%3BHoffman%2C+T%3BTaplits%2C+M&rft.aulast=Bonvini&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Turnover of tPA in rabbits AN - 41229055; 1729951 AU - Beebe, D AU - Aronson, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41229055?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Turnover+of+tPA+in+rabbits&rft.au=Beebe%2C+D%3BAronson%2C+D&rft.aulast=Beebe&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction, persistence, and strain specificity of hemagglutinin-specific pulmonary antibodies after intragastric immunization with inactivated influenza virus vaccines AN - 41228530; 1739280 AU - Chen, K-S AU - Quinnan, GV Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41228530?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction%2C+persistence%2C+and+strain+specificity+of+hemagglutinin-specific+pulmonary+antibodies+after+intragastric+immunization+with+inactivated+influenza+virus+vaccines&rft.au=Chen%2C+K-S%3BQuinnan%2C+GV+Jr&rft.aulast=Chen&rft.aufirst=K-S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Taurine uptake by rat alveolar macrophages and type II cells AN - 41227016; 1761763 AU - Banks, MA AU - Martin, W G AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41227016?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Taurine+uptake+by+rat+alveolar+macrophages+and+type+II+cells&rft.au=Banks%2C+MA%3BMartin%2C+W+G%3BCastranova%2C+V&rft.aulast=Banks&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Expression of pre-S2 region of hepatitis B surface antigen in E. coli AN - 41224141; 1753282 AU - Yu, M W AU - Shih, JW-K AU - Burstyn-Pettegrew, H AU - Chan, H W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41224141?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Expression+of+pre-S2+region+of+hepatitis+B+surface+antigen+in+E.+coli&rft.au=Yu%2C+M+W%3BShih%2C+JW-K%3BBurstyn-Pettegrew%2C+H%3BChan%2C+H+W&rft.aulast=Yu&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Interferon- beta 2/B cell stimulatory factor 2/IL-6 is a growth factor for Epstein-Barr virus-infected human B cells AN - 41220206; 1732363 AU - Tosato, G AU - Jones, K D AU - Pike, SE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41220206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Interferon-+beta+2%2FB+cell+stimulatory+factor+2%2FIL-6+is+a+growth+factor+for+Epstein-Barr+virus-infected+human+B+cells&rft.au=Tosato%2C+G%3BJones%2C+K+D%3BPike%2C+SE&rft.aulast=Tosato&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - ICRF-187 Pretreatment markedly increases the tolerated cumulative dose of doxorubicin in beagle dogs AN - 41210750; 1743777 AU - Herman, E AU - Ferrans, V AU - Hamlin, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41210750?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=ICRF-187+Pretreatment+markedly+increases+the+tolerated+cumulative+dose+of+doxorubicin+in+beagle+dogs&rft.au=Herman%2C+E%3BFerrans%2C+V%3BHamlin%2C+R&rft.aulast=Herman&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Growth and feather development in quail: B vitamin deficiencies versus TVP feeding AN - 41209503; 1731995 AU - Tao, S-H AU - Fox AU - Fry, BE Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41209503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Growth+and+feather+development+in+quail%3A+B+vitamin+deficiencies+versus+TVP+feeding&rft.au=Tao%2C+S-H%3BFox%3BFry%2C+BE+Jr&rft.aulast=Tao&rft.aufirst=S-H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Price: $75.00 (FASEB J. personal subscribers), $150.00 (FASEB J. institutional subscribers), $60.00 abstracts issues. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Binding characteristics and protective immunity of monoclonal antibodies to pneumococcal type 9V conjugate AN - 41204521; 3246655 AU - Lee, C AU - Wang, T AU - Kosaka, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine KW - U 1500:Biochemistry KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41204521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Binding+characteristics+and+protective+immunity+of+monoclonal+antibodies+to+pneumococcal+type+9V+conjugate&rft.au=Lee%2C+C%3BWang%2C+T%3BKosaka%2C+T&rft.aulast=Lee&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Federation of American Societies for Experimental Biology, 9650 Rockville Pike, Bethesda, MD 20814-3998, Abstracts available. Paper No. 472 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Specific inhibition of graft rejection by soluble MHC superdimers AN - 41194080; 3248910 AU - Schneck, J P AU - Sechler, J AU - O'Herrin, S M AU - Bieler, J G AU - Barnes, N AU - Rosenberg, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine KW - U 1500:Biochemistry KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41194080?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Specific+inhibition+of+graft+rejection+by+soluble+MHC+superdimers&rft.au=Schneck%2C+J+P%3BSechler%2C+J%3BO%27Herrin%2C+S+M%3BBieler%2C+J+G%3BBarnes%2C+N%3BRosenberg%2C+A&rft.aulast=Schneck&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Federation of American Societies for Experimental Biology, 9650 Rockville Pike, Bethesda, MD 20814-3998, Abstracts available. Paper No. 2729 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - B72 costimulation is required for Th2 but not Th1-mediated responses to ovalbumin AN - 41189657; 3246391 AU - Scott, DE AU - Agranovich, I AU - Golding, B AU - Golding, H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine KW - U 4500:Experimental Medicine KW - U 1500:Biochemistry KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41189657?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=B72+costimulation+is+required+for+Th2+but+not+Th1-mediated+responses+to+ovalbumin&rft.au=Scott%2C+DE%3BAgranovich%2C+I%3BGolding%2C+B%3BGolding%2C+H&rft.aulast=Scott&rft.aufirst=DE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Federation of American Societies for Experimental Biology, 9650 Rockville Pike, Bethesda, MD 20814-3998, Abstracts available. Paper No. 208 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Medical applications of ultraviolet lasers AN - 41183180; 1671165 AU - Waynant, R W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4000:ELECTRICAL ENGINEERING KW - U 8000:PHYSICS AND ASTRONOMY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41183180?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Medical+applications+of+ultraviolet+lasers&rft.au=Waynant%2C+R+W&rft.aulast=Waynant&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: SPIE, P.O. Box 10, Bellingham, WA 98227 (USA); telephone (206) 676-3290, Proceedings volumes available Paper No. 894-13 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of an in vitro cardiac pulse duplicator AN - 41181569; 1607105 AU - Robinson, R A AU - Carey, R F AU - Herman, BA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41181569?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Evaluation+of+an+in+vitro+cardiac+pulse+duplicator&rft.au=Robinson%2C+R+A%3BCarey%2C+R+F%3BHerman%2C+BA&rft.aulast=Robinson&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Alliance for Engineering in Medicine and Biology, 1101 Connecticut Avenue, N.W., Washington, DC 20036 (USA). Telephone: (202) 857-1199, Abstract No. 9.6 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Fish species identification using computer-assisted pattern recognition with isoelectric focusing protein patterns from a World Wide Web accessible regulatory fish encyclopedia AN - 41172546; 3245517 AU - Tenge, B J AU - Dang, N-L AU - Fry, F S AU - Rogers, P L AU - Savary, W E AU - Barnett, J D AU - Wekell, M M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41172546?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Fish+species+identification+using+computer-assisted+pattern+recognition+with+isoelectric+focusing+protein+patterns+from+a+World+Wide+Web+accessible+regulatory+fish+encyclopedia&rft.au=Tenge%2C+B+J%3BDang%2C+N-L%3BFry%2C+F+S%3BRogers%2C+P+L%3BSavary%2C+W+E%3BBarnett%2C+J+D%3BWekell%2C+M+M&rft.aulast=Tenge&rft.aufirst=B&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: IFT Customer Service, 221 N. 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Paper No. 80D-3 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assurance for food safety-residue analytical science AN - 41168552; 3245054 AU - O'Rangers, J J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41168552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Assurance+for+food+safety-residue+analytical+science&rft.au=O%27Rangers%2C+J+J&rft.aulast=O%27Rangers&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: IFT Customer Service, 221 N. 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Paper No. 43-4 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Offshore suspension relaying as a means of reducing levels of Vibrio vulnificus in gulf coast oysters AN - 41158672; 3245206 AU - Motes, M L AU - DePaola, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41158672?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Offshore+suspension+relaying+as+a+means+of+reducing+levels+of+Vibrio+vulnificus+in+gulf+coast+oysters&rft.au=Motes%2C+M+L%3BDePaola%2C+A&rft.aulast=Motes&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: IFT Customer Service, 221 N. 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Paper No. 53D-17 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Microcomputer/flexible diskette submission--floppy diskette program development AN - 41156501; 1549170 AU - Dong, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41156501?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Microcomputer%2Fflexible+diskette+submission--floppy+diskette+program+development&rft.au=Dong%2C+M&rft.aulast=Dong&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Drug Information Association, P.O. 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Telephone: (215) 628-2288 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Summary and projections for the future: Implications for worldwide safety data reporting AN - 41151269; 1549179 AU - Anello, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41151269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Summary+and+projections+for+the+future%3A+Implications+for+worldwide+safety+data+reporting&rft.au=Anello%2C+C&rft.aulast=Anello&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Drug Information Association, P.O. Box 113, Maple Glen, PA 19002 (USA). Telephone: (215) 628-2288 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Analysis of neurohumoral mechanism of tubocurarine potentiation by struggling AN - 41149046; 1550120 AU - Hohmann, J R AU - Ellis, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41149046?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Analysis+of+neurohumoral+mechanism+of+tubocurarine+potentiation+by+struggling&rft.au=Hohmann%2C+J+R%3BEllis%2C+S&rft.aulast=Hohmann&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 6572 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Coplanar PCBs and the relative contribution of coplanar PCBs, PCDDs, and PCDFs to the total 2,3,7,8-TCDD toxicity equivalents in human serum AN - 41148028; 3218568 AU - Kang, D AU - Tepper, A AU - Patterson, DG Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41148028?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+research&rft.atitle=Single-site+methylation+within+the+p53+promoter+region+reduces+gene+expression+in+a+reporter+gene+construct%3A+possible+in+vivo+relevance+during+tumorigenesis.&rft.au=Pogribny%2C+I+P%3BPogribna%2C+M%3BChristman%2C+J+K%3BJames%2C+S+J&rft.aulast=Pogribny&rft.aufirst=I&rft.date=2000-02-01&rft.volume=60&rft.issue=3&rft.spage=588&rft.isbn=&rft.btitle=&rft.title=Cancer+research&rft.issn=00085472&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society for Occupational & Environmental Health, 6728 Old McLean Village Drive, McLean, VA 22101, Expanded abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Multi-center study of rubber latex specific IgE antibodies among U.S. hospital personnel AN - 41147204; 3218519 AU - Kaczmarek, R G AU - Silverman, B G AU - Gross, T P AU - Hamilton, R G AU - Kessler, E AU - Arrowsmith-Lowe, J T AU - Moore, RM Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41147204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Multi-center+study+of+rubber+latex+specific+IgE+antibodies+among+U.S.+hospital+personnel&rft.au=Kaczmarek%2C+R+G%3BSilverman%2C+B+G%3BGross%2C+T+P%3BHamilton%2C+R+G%3BKessler%2C+E%3BArrowsmith-Lowe%2C+J+T%3BMoore%2C+RM+Jr&rft.aulast=Kaczmarek&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society for Occupational & Environmental Health, 6728 Old McLean Village Drive, McLean, VA 22101, Expanded abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Bayesian estimation for TDM of anticancer drugs: Evaluation of different population methods AN - 41144439; 3214927 AU - Nakashima, H AU - Lieberman, R AU - Karato, A AU - Saijo, N Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41144439?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Bayesian+estimation+for+TDM+of+anticancer+drugs%3A+Evaluation+of+different+population+methods&rft.au=Nakashima%2C+H%3BLieberman%2C+R%3BKarato%2C+A%3BSaijo%2C+N&rft.aulast=Nakashima&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800, Abstracts available. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - PCR method for the detection of Helicobacter pylori in food products AN - 41143072; 3234832 AU - Cohen, A E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41143072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=PCR+method+for+the+detection+of+Helicobacter+pylori+in+food+products&rft.au=Ball%2C+R%3BParker%2C+E+C&rft.aulast=Ball&rft.aufirst=R&rft.date=2000-02-01&rft.volume=71&rft.issue=2&rft.spage=102&rft.isbn=&rft.btitle=&rft.title=Aviation%2C+Space+and+Environmental+Medicine&rft.issn=00956562&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Department of Food Hygiene, PO Box 7009, Faculty of Veterinary Medicine, SLU S-750 07, Uppsala, Sweden, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Influence of dietary uptake on chemical toxicity AN - 41135975; 3211689 AU - Hart, R W AU - Turturro, A AU - Duff, PH AU - Feuers, R J AU - Lu, Ming Hsiug AU - Leakey, JEA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41135975?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Influence+of+dietary+uptake+on+chemical+toxicity&rft.au=Hart%2C+R+W%3BTurturro%2C+A%3BDuff%2C+PH%3BFeuers%2C+R+J%3BLu%2C+Ming+Hsiug%3BLeakey%2C+JEA&rft.aulast=Hart&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: National Research Centre, Professor Dr. Sameeh A. Mansour, Dokki, Cairo, Egypt Fax: (202)337-0931, Full papers available. Paper No. PL 5.1 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Synthesis and characterization of a hydroxy metabolite of p-chloro-m-xylenol (PCMX) AN - 41133181; 3217084 AU - Reepmeyer, J C AU - Zielinski, W L AU - Leakey, J AU - Si, Ying Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2500:Chemistry and Chemical Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41133181?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Synthesis+and+characterization+of+a+hydroxy+metabolite+of+p-chloro-m-xylenol+%28PCMX%29&rft.au=Reepmeyer%2C+J+C%3BZielinski%2C+W+L%3BLeakey%2C+J%3BSi%2C+Ying&rft.aulast=Reepmeyer&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Pittsburgh Conference on Analytical Chemistry And Applied Spectroscopy, 300 Penn Center Boulevard, Suite 332, Pittsburgh, PA 15235, Abstracts available. Poster Paper No. 546P N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - New strategies for the evaluation of the carcinogenic activities of chemicals AN - 41127487; 3211677 AU - Schwetz, BA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41127487?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=New+strategies+for+the+evaluation+of+the+carcinogenic+activities+of+chemicals&rft.au=Schwetz%2C+BA&rft.aulast=Schwetz&rft.aufirst=BA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: National Research Centre, Professor Dr. Sameeh A. Mansour, Dokki, Cairo, Egypt Fax: (202)337-0931, Full papers available. Paper No. PL 1.1 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Health-related effects of insect rearing AN - 41125524; 3223088 AU - Short, S AU - Petsonk, L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41125524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Health-related+effects+of+insect+rearing&rft.au=Short%2C+S%3BPetsonk%2C+L&rft.aulast=Short&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Entomological Society of America, 9301 Annapolis Road, Lanham, MD 20706, Contact individual authors concerning paper availability. Paper No. 0303 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Manganese-induced neurotoxicity: Recent advances in experimental research AN - 41123599; 3211682 AU - Ali, S F AU - Duhart, H M AU - Lipe, G W AU - Schmued, L AU - Slikker, W Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41123599?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Manganese-induced+neurotoxicity%3A+Recent+advances+in+experimental+research&rft.au=Ali%2C+S+F%3BDuhart%2C+H+M%3BLipe%2C+G+W%3BSchmued%2C+L%3BSlikker%2C+W+Jr&rft.aulast=Ali&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: National Research Centre, Professor Dr. Sameeh A. Mansour, Dokki, Cairo, Egypt Fax: (202)337-0931, Full papers available. Paper No. PL 2.3 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - On population pharmacokinetic model stability and performance AN - 41119030; 3214638 AU - Ette, E I AU - Sahajwalla, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41119030?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=On+population+pharmacokinetic+model+stability+and+performance&rft.au=Ette%2C+E+I%3BSahajwalla%2C+C&rft.aulast=Ette&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Clinical Pharmacology and Therapeutics, 1718 Gallagher Road, Norristown, PA 19401-2800, Abstracts available. Poster Paper N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Is physical load at work reduced with increasing age? A pilot study AN - 41084173; 3191238 AU - Kilbom, A AU - Winkel, J AU - Kariqvist, L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41084173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Is+physical+load+at+work+reduced+with+increasing+age%3F+A+pilot+study&rft.au=Kilbom%2C+A%3BWinkel%2C+J%3BKariqvist%2C+L&rft.aulast=Kilbom&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Institut de Recherche en Sante et en Securite du Travail, Direction des Communications, 505 de Maisonneuve Boulevard, West, Montreal (Quebec) H3A 3C2, Canada, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Methods for evaluating risks of non-cancer endpoints in epidemiology studies AN - 41082335; 3191912 AU - Bailer, A J AU - Stayner, L T AU - Smith, R J AU - Prince, M AU - Kuempel, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41082335?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Methods+for+evaluating+risks+of+non-cancer+endpoints+in+epidemiology+studies&rft.au=Bailer%2C+A+J%3BStayner%2C+L+T%3BSmith%2C+R+J%3BPrince%2C+M%3BKuempel%2C+E&rft.aulast=Bailer&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Williams & Wilkins, 351 West Camden Street, Baltimore, MD 21201-2436, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Silicosis among gold-miners: Exposure-response analyses and risk assessment AN - 41081600; 3192058 AU - Steenland, K AU - Brown, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41081600?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Silicosis+among+gold-miners%3A+Exposure-response+analyses+and+risk+assessment&rft.au=Steenland%2C+K%3BBrown%2C+D&rft.aulast=Steenland&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Williams & Wilkins, 351 West Camden Street, Baltimore, MD 21201-2436, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A study of the immunotoxic effects of lead AN - 41081531; 3192008 AU - Pinkerton, LE AU - Biagini, R AU - Ward, E AU - Hull, R D AU - Boeniger, M AU - Schnorr, T AU - Luster, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:Experimental Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41081531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=A+study+of+the+immunotoxic+effects+of+lead&rft.au=Pinkerton%2C+LE%3BBiagini%2C+R%3BWard%2C+E%3BHull%2C+R+D%3BBoeniger%2C+M%3BSchnorr%2C+T%3BLuster%2C+M&rft.aulast=Pinkerton&rft.aufirst=LE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Williams & Wilkins, 351 West Camden Street, Baltimore, MD 21201-2436, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Improved differential fiber length classifier AN - 41071998; 3199062 AU - Baron, P A AU - Deye, G J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2500:Chemistry and Chemical Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41071998?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Improved+differential+fiber+length+classifier&rft.au=Baron%2C+P+A%3BDeye%2C+G+J&rft.aulast=Baron&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The American Society for Aerosol Research, Kemper Woods Center, 1330 Kemper Meadow Drive, Cincinnati, OH 45240. Ph: 513-742-2227; Fax: 513-742-3355., Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An evaluation of back injury risk among grocery warehouse workers AN - 41070099; 3201097 AU - Baron, S AU - Putz-Anderson, V AU - Waters, T AU - Hanley, K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:Clinical Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41070099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=An+evaluation+of+back+injury+risk+among+grocery+warehouse+workers&rft.au=Baron%2C+S%3BPutz-Anderson%2C+V%3BWaters%2C+T%3BHanley%2C+K&rft.aulast=Baron&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Institut de Recherche en Sante et en Securite du Travail, Direction des Communications, 505 de Maisonneuve Boulevard, West, Montreal (Quebec) H3A 3C2, Canada, Abstracts available. N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of human lymphoblastoid cells expressing human cytochrome P450S or human udp-glucuronosyltransferases for mechanistic studies of human drug metabolism AN - 41068693; 3199763 AU - Frame, L T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:Pharmacology KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41068693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Use+of+human+lymphoblastoid+cells+expressing+human+cytochrome+P450S+or+human+udp-glucuronosyltransferases+for+mechanistic+studies+of+human+drug+metabolism&rft.au=Frame%2C+L+T&rft.aulast=Frame&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: International Society for Xenobiotics, PO Box 3, Cabin John, MD 20818, Abstracts available. Price $25. Poster Paper No. 372 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dietary effects on fecal mutagen production in pigs AN - 41051859; 1508139 AU - Pertel, R AU - Sellers, RL Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41051859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Dietary+effects+on+fecal+mutagen+production+in+pigs&rft.au=Pertel%2C+R%3BSellers%2C+RL+Jr&rft.aulast=Pertel&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 701 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Protein efficiency ratios and net protein ratios of selected protein foods AN - 41045926; 1537558 AU - Grundel, E AU - Mitchell, G V AU - Jenkins, MY Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41045926?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Protein+efficiency+ratios+and+net+protein+ratios+of+selected+protein+foods&rft.au=Grundel%2C+E%3BMitchell%2C+G+V%3BJenkins%2C+MY&rft.aulast=Grundel&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 3341 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Regulation of the biosynthesis of C-reactive protein in hepatoma cells by a monocyte factor AN - 41045569; 1535265 AU - Goldman, N AU - Washington, G AU - Liu, T-Y Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41045569?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Regulation+of+the+biosynthesis+of+C-reactive+protein+in+hepatoma+cells+by+a+monocyte+factor&rft.au=Goldman%2C+N%3BWashington%2C+G%3BLiu%2C+T-Y&rft.aulast=Goldman&rft.aufirst=N&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 2763 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A 34 kilodalton GTP binding protein associated with the T cell receptor complex AN - 41043572; 1544750 AU - Laurenza, A AU - Seamon, K B AU - Berkower, I Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41043572?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=A+34+kilodalton+GTP+binding+protein+associated+with+the+T+cell+receptor+complex&rft.au=Laurenza%2C+A%3BSeamon%2C+K+B%3BBerkower%2C+I&rft.aulast=Laurenza&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 5133 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of histamine releasing factor (HRF) synthesis in guinea pigs: Simultaneous production of a histamine release inhibitory factor and an inhibitor of HRF synthesis by lymphocytes AN - 41036668; 1538374 AU - Alam, R AU - Lewis, D M AU - Olenchock, SA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41036668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction+of+histamine+releasing+factor+%28HRF%29+synthesis+in+guinea+pigs%3A+Simultaneous+production+of+a+histamine+release+inhibitory+factor+and+an+inhibitor+of+HRF+synthesis+by+lymphocytes&rft.au=Alam%2C+R%3BLewis%2C+D+M%3BOlenchock%2C+SA&rft.aulast=Alam&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 3562 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Restoration of ability to respond to polysaccharide antigens in xid mice by neonatal priming with Id or anti-Id AN - 41035884; 1541141 AU - Stein, KE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41035884?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Restoration+of+ability+to+respond+to+polysaccharide+antigens+in+xid+mice+by+neonatal+priming+with+Id+or+anti-Id&rft.au=Stein%2C+KE&rft.aulast=Stein&rft.aufirst=KE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 4127 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Nephrotoxicity of cyclosporine A in pregnant, nonpregnant and fetal rats AN - 41034090; 1543639 AU - Alleva AU - Cockrell, B Y AU - Balazs, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41034090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Nephrotoxicity+of+cyclosporine+A+in+pregnant%2C+nonpregnant+and+fetal+rats&rft.au=Alleva%3BCockrell%2C+B+Y%3BBalazs%2C+T&rft.aulast=Alleva&rft.aufirst=&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 4805 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of modifications of the AIN-76A diet on selected nutritional parameters and incidence of pathology AN - 41030070; 1538094 AU - Mitchell, G V AU - Dua, P N AU - Jenkins, MY AU - Grundel, E AU - Arzadon, J M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41030070?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+modifications+of+the+AIN-76A+diet+on+selected+nutritional+parameters+and+incidence+of+pathology&rft.au=Mitchell%2C+G+V%3BDua%2C+P+N%3BJenkins%2C+MY%3BGrundel%2C+E%3BArzadon%2C+J+M&rft.aulast=Mitchell&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 3489 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Aluminum in Total Diet Study foods and diets AN - 41029904; 1540767 AU - Pennington, JAT AU - Jones, J W AU - Vanderveen, JE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41029904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Aluminum+in+Total+Diet+Study+foods+and+diets&rft.au=Pennington%2C+JAT%3BJones%2C+J+W%3BVanderveen%2C+JE&rft.aulast=Pennington&rft.aufirst=JAT&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 3999 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Plasminogen activation and platelet adhesion to biomaterials AN - 41028975; 1583921 AU - Feri, JE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41028975?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Plasminogen+activation+and+platelet+adhesion+to+biomaterials&rft.au=Feri%2C+JE&rft.aulast=Feri&rft.aufirst=JE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society for Biomaterials, Box 49, University of Alabama School of Dentistry, Birmingham 35294, AL (USA), Poster Paper No. 126 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Direct effect of cocaine on the heart AN - 41028505; 1543778 AU - Herman, E H AU - Vick, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41028505?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Direct+effect+of+cocaine+on+the+heart&rft.au=Herman%2C+E+H%3BVick%2C+J&rft.aulast=Herman&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 4840 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Maturation of influenza virus-specific cytotoxic lymphocytes requires a lymphokine distinct from IL-2 AN - 41027075; 1535185 AU - Horohov, D W AU - Stocks, NI AU - Siegel, J P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41027075?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Maturation+of+influenza+virus-specific+cytotoxic+lymphocytes+requires+a+lymphokine+distinct+from+IL-2&rft.au=Horohov%2C+D+W%3BStocks%2C+NI%3BSiegel%2C+J+P&rft.aulast=Horohov&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 2738 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Iron nutritional status of females aged 20 to 44 yrs in Hispanic HANES AN - 41025668; 1537275 AU - Yetley, E A AU - McDowell, MA AU - Looker, A C AU - Johnson, CL Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41025668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Iron+nutritional+status+of+females+aged+20+to+44+yrs+in+Hispanic+HANES&rft.au=Yetley%2C+E+A%3BMcDowell%2C+MA%3BLooker%2C+A+C%3BJohnson%2C+CL&rft.aulast=Yetley&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 3266 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Impact of zinc depletion on behavioral function in weanling rats AN - 41024566; 1537830 AU - Sobotka, T AU - Rader, J AU - Brodie, R AU - Quander, Y AU - West, G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41024566?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Impact+of+zinc+depletion+on+behavioral+function+in+weanling+rats&rft.au=Sobotka%2C+T%3BRader%2C+J%3BBrodie%2C+R%3BQuander%2C+Y%3BWest%2C+G&rft.aulast=Sobotka&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 3417 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of buffered saline-benzyl alcohol as a storage solution for explanted bioprosthetic heart valves AN - 41023366; 1584024 AU - Hilbert, S L AU - Ferrans, V J AU - Yoganathan, A AU - Jones, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41023366?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Use+of+buffered+saline-benzyl+alcohol+as+a+storage+solution+for+explanted+bioprosthetic+heart+valves&rft.au=Hilbert%2C+S+L%3BFerrans%2C+V+J%3BYoganathan%2C+A%3BJones%2C+M&rft.aulast=Hilbert&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society for Biomaterials, Box 49, University of Alabama School of Dentistry, Birmingham 35294, AL (USA), Poster Paper No. 202 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of serving size, food patterns and socioeconomic characteristics of diet cola consumers versus regular cola consumers AN - 41022407; 1528435 AU - Lewis, C J AU - Crane, N T AU - Hanson, E A AU - Yetley, E A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41022407?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparison+of+serving+size%2C+food+patterns+and+socioeconomic+characteristics+of+diet+cola+consumers+versus+regular+cola+consumers&rft.au=Lewis%2C+C+J%3BCrane%2C+N+T%3BHanson%2C+E+A%3BYetley%2C+E+A&rft.aulast=Lewis&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 1612 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Airway epithelium modulates Na super(+)/K super(+) pumping and Na super(+)/H super(+) exchange in guinea pig trachealis AN - 41021499; 1500027 AU - Farmer, S G AU - Hay, DWP AU - Fedan, J S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41021499?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Airway+epithelium+modulates+Na+super%28%2B%29%2FK+super%28%2B%29+pumping+and+Na+super%28%2B%29%2FH+super%28%2B%29+exchange+in+guinea+pig+trachealis&rft.au=Farmer%2C+S+G%3BHay%2C+DWP%3BFedan%2C+J+S&rft.aulast=Farmer&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA), Paper No. 343 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Gene probe to detect hemolytic Listeria strains AN - 41011733; 1478501 AU - Datta, A R AU - Flamm, R K AU - Wentz, BA AU - Thomashow, M F AU - Hill, W E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41011733?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Gene+probe+to+detect+hemolytic+Listeria+strains&rft.au=Datta%2C+A+R%3BFlamm%2C+R+K%3BWentz%2C+BA%3BThomashow%2C+M+F%3BHill%2C+W+E&rft.aulast=Datta&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publication Sales, 1913 I Street, N.W., Washington, DC 20006 (USA). Telephone: (202) 833-9680, Price: $20.00 (abstracts); $3.00 (program) Abstract No. P28 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of proteolysis on pertussis toxin AN - 41009226; 1470329 AU - Hausman, S Z AU - Burns, D L AU - Manclark, C R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41009226?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+proteolysis+on+pertussis+toxin&rft.au=Hausman%2C+S+Z%3BBurns%2C+D+L%3BManclark%2C+C+R&rft.aulast=Hausman&rft.aufirst=S&rft.date=2000-12-31&rft.volume=20&rft.issue=2&rft.spage=187&rft.isbn=&rft.btitle=&rft.title=Alcohol&rft.issn=07418329&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publication Sales, 1913 I Street, N.W., Washington, DC 20006 (USA). Telephone: (202) 833-9680, Price: $20.00 (abstracts); $3.00 (program) Abstract No. B75 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Incidence of antibiotic resistance in gram-negative bacteria from cultured catfish and aquaculture ponds AN - 41007788; 1481462 AU - McPhearson, R M AU - Zywno AU - Depaola, A AU - Motes, ML Jr AU - Guarino, A M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/41007788?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Incidence+of+antibiotic+resistance+in+gram-negative+bacteria+from+cultured+catfish+and+aquaculture+ponds&rft.au=McPhearson%2C+R+M%3BZywno%3BDepaola%2C+A%3BMotes%2C+ML+Jr%3BGuarino%2C+A+M&rft.aulast=McPhearson&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publication Sales, 1913 I Street, N.W., Washington, DC 20006 (USA). Telephone: (202) 833-9680, Price: $20.00 (abstracts); $3.00 (program) Abstract No. Q142 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cross-reaction between Shigella species envelope proteins and HLA-B27 AN - 40999815; 1478311 AU - Raybourne, R AU - Bunning, V K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40999815?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Cross-reaction+between+Shigella+species+envelope+proteins+and+HLA-B27&rft.au=Raybourne%2C+R%3BBunning%2C+V+K&rft.aulast=Raybourne&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publication Sales, 1913 I Street, N.W., Washington, DC 20006 (USA). Telephone: (202) 833-9680, Price: $20.00 (abstracts); $3.00 (program) Abstract No. D143 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Salmonella typhimurium suppresses the immunoglobulin A immune response of both Peyer's patch and splenic lymphocytes AN - 40991154; 1474956 AU - Wess, JA AU - Petro, T M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40991154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Salmonella+typhimurium+suppresses+the+immunoglobulin+A+immune+response+of+both+Peyer%27s+patch+and+splenic+lymphocytes&rft.au=Wess%2C+JA%3BPetro%2C+T+M&rft.aulast=Wess&rft.aufirst=JA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publication Sales, 1913 I Street, N.W., Washington, DC 20006 (USA). Telephone: (202) 833-9680, Price: $20.00 (abstracts); $3.00 (program) Abstract No. E55 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Oral infectivity of Vibrio vulnificus AN - 40986568; 1466734 AU - Reyes, AL AU - Johnson, CH AU - Spaulding, P L AU - Stelma, GN Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40986568?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Oral+infectivity+of+Vibrio+vulnificus&rft.au=Reyes%2C+AL%3BJohnson%2C+CH%3BSpaulding%2C+P+L%3BStelma%2C+GN+Jr&rft.aulast=Reyes&rft.aufirst=AL&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publication Sales, 1913 I Street, N.W., Washington, DC 20006 (USA). Telephone: (202) 833-9680, Price: $20.00 (abstracts); $3.00 (program) Abstract No. P12 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - System to analyze fields produced by osteogenesis devices AN - 40980990; 1397990 AU - Ho, H S AU - Kantor, G AU - Allen, S J AU - Athey, T W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40980990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=System+to+analyze+fields+produced+by+osteogenesis+devices&rft.au=Ho%2C+H+S%3BKantor%2C+G%3BAllen%2C+S+J%3BAthey%2C+T+W&rft.aulast=Ho&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Alliance for Engineering in Medicine and Biology, Suite 700, 1101 Connecticut Avenue, N.W., Washington, DC 20036 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Ultrasonic texture analysis: Tissue signatures from video data AN - 40967324; 1395359 AU - Insana, M F AU - Smith, S W AU - Carroll, BA AU - Hubbard, S M AU - Garra, B S AU - Trahey, GE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40967324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Ultrasonic+texture+analysis%3A+Tissue+signatures+from+video+data&rft.au=Insana%2C+M+F%3BSmith%2C+S+W%3BCarroll%2C+BA%3BHubbard%2C+S+M%3BGarra%2C+B+S%3BTrahey%2C+GE&rft.aulast=Insana&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Alliance for Engineering in Medicine and Biology, Suite 700, 1101 Connecticut Avenue, N.W., Washington, DC 20036 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Chemical inactivation of pertussis toxin AN - 40930941; 1256642 AU - Duncan, R C AU - Burns, D L AU - Manclark, C R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40930941?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Chemical+inactivation+of+pertussis+toxin&rft.au=Duncan%2C+R+C%3BBurns%2C+D+L%3BManclark%2C+C+R&rft.aulast=Duncan&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1913 I Street, N.W., Washington, DC 20006 (USA), Abstract No. B11 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Serum bactericidal antibodies against Neisseria meningitidis groups B, Z, and 29E measured using human and rabbit complement AN - 40929176; 1320031 AU - Mocca, L F AU - Frasch, CE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40929176?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Serum+bactericidal+antibodies+against+Neisseria+meningitidis+groups+B%2C+Z%2C+and+29E+measured+using+human+and+rabbit+complement&rft.au=Mocca%2C+L+F%3BFrasch%2C+CE&rft.aulast=Mocca&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. E53 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Staphylococcal enterotoxin A increases murine resistance to Listeria monocytogenes by elevating granulocyte/macrophage progenitor levels AN - 40922645; 1323387 AU - Petro, T M AU - Smith, B G AU - Wess, JA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40922645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Staphylococcal+enterotoxin+A+increases+murine+resistance+to+Listeria+monocytogenes+by+elevating+granulocyte%2Fmacrophage+progenitor+levels&rft.au=Petro%2C+T+M%3BSmith%2C+B+G%3BWess%2C+JA&rft.aulast=Petro&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. E66 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Quantitation of lipopolysaccharide (endotoxin) impurity in purified polysaccharide or protein vaccines of gram-negative bacteria by silver staining following sodium dodecyl sulfate-polyacrylamide gel electrophoresis AN - 40921188; 1324311 AU - Tsai, C-M AU - Frasch, CE Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40921188?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Quantitation+of+lipopolysaccharide+%28endotoxin%29+impurity+in+purified+polysaccharide+or+protein+vaccines+of+gram-negative+bacteria+by+silver+staining+following+sodium+dodecyl+sulfate-polyacrylamide+gel+electrophoresis&rft.au=Tsai%2C+C-M%3BFrasch%2C+CE&rft.aulast=Tsai&rft.aufirst=C-M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. B175 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - DNA homology and immunological cross-reactivity between Aeromonas hydrophila cytotonic toxin and cholera toxin AN - 40920691; 1323591 AU - Schultz, A J AU - Hill, W E AU - McCardell, BA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40920691?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=DNA+homology+and+immunological+cross-reactivity+between+Aeromonas+hydrophila+cytotonic+toxin+and+cholera+toxin&rft.au=Schultz%2C+A+J%3BHill%2C+W+E%3BMcCardell%2C+BA&rft.aulast=Schultz&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. B242 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Relationship of specific virulence factors to pathogenicity in Vibrio vulnificus AN - 40911870; 1300528 AU - Stelma, GN Jr AU - Reynes, AL Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40911870?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Relationship+of+specific+virulence+factors+to+pathogenicity+in+Vibrio+vulnificus&rft.au=Stelma%2C+GN+Jr%3BReynes%2C+AL&rft.aulast=Stelma&rft.aufirst=GN&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, 1913 I Street, N.W., Washington, DC 20006 (USA), Abstract No. P3 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Human T cell clone specific for HBsAg is restricted to HLA-A11 and cross-reacts with A2 AN - 40908452; 1199625 AU - Jin, Y AU - Shih, J W AU - Alter, H AU - Berkower, I Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40908452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Human+T+cell+clone+specific+for+HBsAg+is+restricted+to+HLA-A11+and+cross-reacts+with+A2&rft.au=Jin%2C+Y%3BShih%2C+J+W%3BAlter%2C+H%3BBerkower%2C+I&rft.aulast=Jin&rft.aufirst=Y&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of chromatographic data systems AN - 40906492; 1238990 AU - Papas, AN AU - Delaney, M F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40906492?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Evaluation+of+chromatographic+data+systems&rft.au=Papas%2C+AN%3BDelaney%2C+M+F&rft.aulast=Papas&rft.aufirst=AN&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Individual authors must be contacted for each paper, Abstract No. 782 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Induction of immunity by antiidiotype in vivo: Is there a primary IgM phase? AN - 40898186; 1196887 AU - Epstein, S L AU - Kindt, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40898186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Induction+of+immunity+by+antiidiotype+in+vivo%3A+Is+there+a+primary+IgM+phase%3F&rft.au=Epstein%2C+S+L%3BKindt%2C+R&rft.aulast=Epstein&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - C3H 10T 1/2 cells are transformed by toxins produced by food molds of the genus Alternaria AN - 40890848; 1178634 AU - Osborne, L AU - Larkin, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40890848?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=C3H+10T+1%2F2+cells+are+transformed+by+toxins+produced+by+food+molds+of+the+genus+Alternaria&rft.au=Osborne%2C+L%3BLarkin%2C+E&rft.aulast=Osborne&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of inositol phosphates on mineral utilization AN - 40888853; 1196342 AU - Tao, S-H AU - Fox AU - Phillippy, B Q AU - Fry, BE Jr AU - Johnson, M L AU - Johnston, M R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40888853?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+inositol+phosphates+on+mineral+utilization&rft.au=Tao%2C+S-H%3BFox%3BPhillippy%2C+B+Q%3BFry%2C+BE+Jr%3BJohnson%2C+M+L%3BJohnston%2C+M+R&rft.aulast=Tao&rft.aufirst=S-H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: FASEB, 9650 Rockville Pike, Bethesda, MD 20814 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Design problem in ulcer prevention trials AN - 40861562; 1114038 AU - Chi, GYH Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 6500:MATHEMATICS UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40861562?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Design+problem+in+ulcer+prevention+trials&rft.au=Chi%2C+GYH&rft.aulast=Chi&rft.aufirst=GYH&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Statistical Association, 806 15th Street, N.W., Washington, DC 20005 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Infectivity and neutralizing activity in sera of patients infected with human T lymphotropic virus, type III AN - 40856125; 1109181 AU - Quinnan, G V AU - Wells, MA AU - Klutch, M AU - Moffitt, A AU - Mayner, R M AU - Phelan, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40856125?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Infectivity+and+neutralizing+activity+in+sera+of+patients+infected+with+human+T+lymphotropic+virus%2C+type+III&rft.au=Quinnan%2C+G+V%3BWells%2C+MA%3BKlutch%2C+M%3BMoffitt%2C+A%3BMayner%2C+R+M%3BPhelan%2C+M&rft.aulast=Quinnan&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publications Department, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. 736 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Association of HLA-DR antigens with influenza A virus-specific cytotoxic-T-lymphocyte responsiveness AN - 40855686; 1110222 AU - Kiley, S C AU - Burlington, D B AU - Wells, MA AU - Mittal, K K AU - Quinnan, GV Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40855686?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Association+of+HLA-DR+antigens+with+influenza+A+virus-specific+cytotoxic-T-lymphocyte+responsiveness&rft.au=Kiley%2C+S+C%3BBurlington%2C+D+B%3BWells%2C+MA%3BMittal%2C+K+K%3BQuinnan%2C+GV+Jr&rft.aulast=Kiley&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publications Department, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. 977 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Selective cultivation of and testing for viral antigens in endothelial cells derived from Kaposi's sarcoma lesions AN - 40854985; 1109610 AU - Mitchell, C D AU - Steis, R AU - Armstrong, G AU - Quinnan, G V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40854985?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Selective+cultivation+of+and+testing+for+viral+antigens+in+endothelial+cells+derived+from+Kaposi%27s+sarcoma+lesions&rft.au=Mitchell%2C+C+D%3BSteis%2C+R%3BArmstrong%2C+G%3BQuinnan%2C+G+V&rft.aulast=Mitchell&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publications Department, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. 823 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Neurotoxic damage to nigrostriatal system following intranigral administration of the oxidative metabolites of MPTP AN - 40853862; 1130535 AU - Sun, C J AU - Richman, D J AU - Gessner, W AU - Brossi, A AU - Johannessen, J N AU - Markey, S P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40853862?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Neurotoxic+damage+to+nigrostriatal+system+following+intranigral+administration+of+the+oxidative+metabolites+of+MPTP&rft.au=Sun%2C+C+J%3BRichman%2C+D+J%3BGessner%2C+W%3BBrossi%2C+A%3BJohannessen%2C+J+N%3BMarkey%2C+S+P&rft.aulast=Sun&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Society for Neuroscience, 11 Dupont Circle, N.W., Suite 130, Washington, DC 20036 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Adjustment for exposure measurement errors in epidemiologic risk assessment AN - 40849060; 1114559 AU - Hornung, R W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 6500:MATHEMATICS UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40849060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Adjustment+for+exposure+measurement+errors+in+epidemiologic+risk+assessment&rft.au=Hornung%2C+R+W&rft.aulast=Hornung&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Statistical Association, 806 15th Street, N.W., Washington, DC 20005 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Studies on Escherichia coli K51 and K93 capsular polysaccharides (CPS) cross-reactive with Neisseria meningitidis group A CPS AN - 40848838; 1104174 AU - Guirguis, N AU - Schneerson, R AU - Bax, A AU - Egan, W AU - Robbins, J B AU - Orskov, F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40848838?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Studies+on+Escherichia+coli+K51+and+K93+capsular+polysaccharides+%28CPS%29+cross-reactive+with+Neisseria+meningitidis+group+A+CPS&rft.au=Guirguis%2C+N%3BSchneerson%2C+R%3BBax%2C+A%3BEgan%2C+W%3BRobbins%2C+J+B%3BOrskov%2C+F&rft.aulast=Guirguis&rft.aufirst=N&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publications Department, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. 70 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Antibodies reactive with HTLV-III found in freezer-banked sera from children in West Africa AN - 40846444; 1105639 AU - Epstein, J S AU - Moffitt, AL AU - Mayner, R E AU - Phelan, MA AU - Meyer, B C AU - Quinnan, G V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40846444?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Antibodies+reactive+with+HTLV-III+found+in+freezer-banked+sera+from+children+in+West+Africa&rft.au=Epstein%2C+J+S%3BMoffitt%2C+AL%3BMayner%2C+R+E%3BPhelan%2C+MA%3BMeyer%2C+B+C%3BQuinnan%2C+G+V&rft.aulast=Epstein&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publications Department, 1913 I Street, N.W., Washington, DC 20006 (USA) N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Physicochemical characteristics of polysaccharides depolymerized by ultrasonic irradiation AN - 40845506; 1104227 AU - Szu, S C AU - Schneerson, R AU - Robbins, J B AU - Zon, G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40845506?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Physicochemical+characteristics+of+polysaccharides+depolymerized+by+ultrasonic+irradiation&rft.au=Szu%2C+S+C%3BSchneerson%2C+R%3BRobbins%2C+J+B%3BZon%2C+G&rft.aulast=Szu&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Society for Microbiology, Publications Department, 1913 I Street, N.W., Washington, DC 20006 (USA), Poster Paper No. 80 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Changing health standards for quartz: Assessing the evidence AN - 40789749; 0985943 AU - Landrigan, P J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:MUTIDISCIPLINARY KW - U 3500:CLINICAL MEDICINE KW - U 2000:BIOLOGY GENERAL KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40789749?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Changing+health+standards+for+quartz%3A+Assessing+the+evidence&rft.au=Landrigan%2C+P+J&rft.aulast=Landrigan&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: AAAS, 1515 Massachusetts Avenue, N.W., Washington, DC 20005, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Differential scanning calorimetry of human albumin: Bimodality at subsaturating concentrations of ligand AN - 40788795; 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0934761 AU - Li, JPC AU - Lee, C-J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40788256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Isolation+and+characterization+of+receptor+molecules+for+pneumococcal+IgG&rft.au=Li%2C+JPC%3BLee%2C+C-J&rft.aulast=Li&rft.aufirst=JPC&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sperm velocity as a measure of the toxic effects of acute EDB exposure AN - 40783543; 0971295 AU - Schrader, S M AU - Turner, T W AU - Clapp, DE AU - Ratcliffe, J M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40783543?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Sperm+velocity+as+a+measure+of+the+toxic+effects+of+acute+EDB+exposure&rft.au=Schrader%2C+S+M%3BTurner%2C+T+W%3BClapp%2C+DE%3BRatcliffe%2C+J+M&rft.aulast=Schrader&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: No ordering information available at the present time, Abstract No. G6 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modulation of high affinity ( super(3)H) forskolin binding sites in rat brain membranes and S49 lymphoma membranes AN - 40781218; 0942893 AU - Seamon, K B AU - Clark, R B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40781218?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Modulation+of+high+affinity+%28+super%283%29H%29+forskolin+binding+sites+in+rat+brain+membranes+and+S49+lymphoma+membranes&rft.au=Seamon%2C+K+B%3BClark%2C+R+B&rft.aulast=Seamon&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Arachiodonic acid (20:4 omega 6) metabolism by prostaglandin synthase and lipoxygenase in stimulated rat macrophage AN - 40776466; 0941618 AU - Marshall, L AU - Becker, W AU - Hoffman, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40776466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Arachiodonic+acid+%2820%3A4+omega+6%29+metabolism+by+prostaglandin+synthase+and+lipoxygenase+in+stimulated+rat+macrophage&rft.au=Marshall%2C+L%3BBecker%2C+W%3BHoffman%2C+T&rft.aulast=Marshall&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Structural analysis of genes related to C-reactive protein AN - 40775052; 0939875 AU - Goldman, N AU - Lei, K-J AU - Liu, T AU - Soravia, E AU - Liu, T-Y Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40775052?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Structural+analysis+of+genes+related+to+C-reactive+protein&rft.au=Goldman%2C+N%3BLei%2C+K-J%3BLiu%2C+T%3BSoravia%2C+E%3BLiu%2C+T-Y&rft.aulast=Goldman&rft.aufirst=N&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Serum K super(+) levels and isoproterenol-induced ventricular fibrillation in heavy rats AN - 40771245; 0933214 AU - Johnson, G L AU - Ehrreich, S J AU - Joseph, X AU - Whitehurst, V AU - Balazs, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40771245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Serum+K+super%28%2B%29+levels+and+isoproterenol-induced+ventricular+fibrillation+in+heavy+rats&rft.au=Johnson%2C+G+L%3BEhrreich%2C+S+J%3BJoseph%2C+X%3BWhitehurst%2C+V%3BBalazs%2C+T&rft.aulast=Johnson&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - C-reactive protein mediates the solubilization of nuclear DNA in vitro AN - 40768943; 0928808 AU - Robey, F A AU - Jones, K D AU - Steinberg, AD Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40768943?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=C-reactive+protein+mediates+the+solubilization+of+nuclear+DNA+in+vitro&rft.au=Robey%2C+F+A%3BJones%2C+K+D%3BSteinberg%2C+AD&rft.aulast=Robey&rft.aufirst=F&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Acute selenium intoxication in the United States AN - 40767997; 0941088 AU - Helzlsouer, K AU - Jacobs, R AU - Morris, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767997?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Acute+selenium+intoxication+in+the+United+States&rft.au=Helzlsouer%2C+K%3BJacobs%2C+R%3BMorris%2C+S&rft.aulast=Helzlsouer&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of long term feeding of soy based diets on the pancreas of Cebus monkeys AN - 40767372; 0936694 AU - Harwood, J P AU - Ausman, L M AU - King, N W AU - Sehgal, P K AU - Nicolosi, R J AU - Liener, I E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40767372?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+long+term+feeding+of+soy+based+diets+on+the+pancreas+of+Cebus+monkeys&rft.au=Harwood%2C+J+P%3BAusman%2C+L+M%3BKing%2C+N+W%3BSehgal%2C+P+K%3BNicolosi%2C+R+J%3BLiener%2C+I+E&rft.aulast=Harwood&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Possible mechanisms by which chlorphentermine causes phospholipidosis in rat alveolar larvage materials AN - 40766925; 0923555 AU - Miles, PR AU - Cheng, W AU - Castranova, V AU - Tucker, J AU - Reasor, MJ AU - Bowman, L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40766925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Possible+mechanisms+by+which+chlorphentermine+causes+phospholipidosis+in+rat+alveolar+larvage+materials&rft.au=Miles%2C+PR%3BCheng%2C+W%3BCastranova%2C+V%3BTucker%2C+J%3BReasor%2C+MJ%3BBowman%2C+L&rft.aulast=Miles&rft.aufirst=PR&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of ICRF-187 on doxorubicin-induced cardiac and renal toxicity in spontaneously hypertensive and normotensive rats AN - 40765954; 0930026 AU - Herman, E AU - El-Hage, A AU - Ferrans, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40765954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+ICRF-187+on+doxorubicin-induced+cardiac+and+renal+toxicity+in+spontaneously+hypertensive+and+normotensive+rats&rft.au=Herman%2C+E%3BEl-Hage%2C+A%3BFerrans%2C+V&rft.aulast=Herman&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Binding of theophylline photoaffinity label analogs to rat whole brain membranes AN - 40761792; 0930037 AU - Fedan, J S AU - Hogaboom, G K AU - Monroe, L D AU - O'Donnell, J P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40761792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Binding+of+theophylline+photoaffinity+label+analogs+to+rat+whole+brain+membranes&rft.au=Fedan%2C+J+S%3BHogaboom%2C+G+K%3BMonroe%2C+L+D%3BO%27Donnell%2C+J+P&rft.aulast=Fedan&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Examination of certain factors which could modify isoproterenol cardiotoxicity in diabetic rats AN - 40760749; 0940908 AU - El-Hage, A AU - Herman, E AU - Whitehurst, V AU - Gudbjarnason, S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40760749?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Examination+of+certain+factors+which+could+modify+isoproterenol+cardiotoxicity+in+diabetic+rats&rft.au=El-Hage%2C+A%3BHerman%2C+E%3BWhitehurst%2C+V%3BGudbjarnason%2C+S&rft.aulast=El-Hage&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of the epithelium in contractile responses of guinea pig isolated trachea AN - 40759566; 0902488 AU - Hay, DWP AU - Robinson, V A AU - Fleming, W W AU - Fedan, J S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40759566?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+the+epithelium+in+contractile+responses+of+guinea+pig+isolated+trachea&rft.au=Hay%2C+DWP%3BRobinson%2C+V+A%3BFleming%2C+W+W%3BFedan%2C+J+S&rft.aulast=Hay&rft.aufirst=DWP&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of various organic solvent vehicles on benzo(a)pyrene metabolism in rabbit lung microsomes AN - 40755978; 0902467 AU - Kontir, D M AU - Glance, C AU - Colby, H D AU - Miles, PR Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+various+organic+solvent+vehicles+on+benzo%28a%29pyrene+metabolism+in+rabbit+lung+microsomes&rft.au=Kontir%2C+D+M%3BGlance%2C+C%3BColby%2C+H+D%3BMiles%2C+PR&rft.aulast=Kontir&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Isolation of a cysteine conjugate beta -lyase with kynureninase activity AN - 40755964; 0912716 AU - Stevens, J L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40755964?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Isolation+of+a+cysteine+conjugate+beta+-lyase+with+kynureninase+activity&rft.au=Stevens%2C+J+L&rft.aulast=Stevens&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Microbial metabolism of pyrene AN - 40754836; 0900305 AU - Cerniglia, CE AU - Kelly, D AU - Freeman, J P AU - Miller, D W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40754836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Microbial+metabolism+of+pyrene&rft.au=Cerniglia%2C+CE%3BKelly%2C+D%3BFreeman%2C+J+P%3BMiller%2C+D+W&rft.aulast=Cerniglia&rft.aufirst=CE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For ordering information contact FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Further characterization of Mycoplasma pneumoniae extract with attachment activity AN - 40715698; 0848412 AU - Chandler, DKF AU - Razin, S AU - Grabowski, M W AU - Barile, M F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40715698?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Further+characterization+of+Mycoplasma+pneumoniae+extract+with+attachment+activity&rft.au=Chandler%2C+DKF%3BRazin%2C+S%3BGrabowski%2C+M+W%3BBarile%2C+M+F&rft.aulast=Chandler&rft.aufirst=DKF&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. G 19 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Increased reliability in the detection of foodborne enterotoxigenic Escherichia coli by DNA colony hybridization AN - 40715661; 0843861 AU - Davis, V M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40715661?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Increased+reliability+in+the+detection+of+foodborne+enterotoxigenic+Escherichia+coli+by+DNA+colony+hybridization&rft.au=Davis%2C+V+M&rft.aulast=Davis&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. P 35 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Incidence and significance of Aeromonas hydrophila along the Gulf Coast AN - 40715111; 0849011 AU - Motes, ML Jr AU - McPhearson, R M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40715111?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Incidence+and+significance+of+Aeromonas+hydrophila+along+the+Gulf+Coast&rft.au=Motes%2C+ML+Jr%3BMcPhearson%2C+R+M&rft.aulast=Motes&rft.aufirst=ML&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. Q 107 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Foodborne enterotoxigenic Escherichia coli : Detection and enumeration on nitrocellulose membrane by enzyme immunoassay AN - 40714664; 0843855 AU - Rhea, U S AU - Shah, D B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40714664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Foodborne+enterotoxigenic+Escherichia+coli+%3A+Detection+and+enumeration+on+nitrocellulose+membrane+by+enzyme+immunoassay&rft.au=Rhea%2C+U+S%3BShah%2C+D+B&rft.aulast=Rhea&rft.aufirst=U&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. P 34 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Adherence of Bordetella pertussis to human WiDr cell cultures AN - 40714419; 0842981 AU - Urisu, A AU - Cowell, J L AU - Manclark, C R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40714419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Adherence+of+Bordetella+pertussis+to+human+WiDr+cell+cultures&rft.au=Urisu%2C+A%3BCowell%2C+J+L%3BManclark%2C+C+R&rft.aulast=Urisu&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. B 65 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Pathogenic Vibrio species, including Vibrio cholerae , from inland bays of the U.S. West Coast AN - 40713239; 0848988 AU - Kaysner, CA AU - Abeyta, C Jr AU - Wekell, M M AU - Depaola, A AU - Stott, R F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40713239?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Pathogenic+Vibrio+species%2C+including+Vibrio+cholerae+%2C+from+inland+bays+of+the+U.S.+West+Coast&rft.au=Kaysner%2C+CA%3BAbeyta%2C+C+Jr%3BWekell%2C+M+M%3BDepaola%2C+A%3BStott%2C+R+F&rft.aulast=Kaysner&rft.aufirst=CA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. Q 98 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Protection against reinfection by Mycoplasma pneumoniae in chimpanzees AN - 40710945; 0848429 AU - Grabowski, M W AU - Graham, CE AU - Pollok, N L AU - Kapatais-Zoumbos, K AU - Chandler, DKF AU - Barile, M F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40710945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Protection+against+reinfection+by+Mycoplasma+pneumoniae+in+chimpanzees&rft.au=Grabowski%2C+M+W%3BGraham%2C+CE%3BPollok%2C+N+L%3BKapatais-Zoumbos%2C+K%3BChandler%2C+DKF%3BBarile%2C+M+F&rft.aulast=Grabowski&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. G 22 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Detection of heat-stable-enterotoxin-producing Escherichia coli by using synthetic oligonucleotides AN - 40709739; 0843863 AU - Hill, W E AU - Payne, W L AU - Zon, G AU - Moseley, S L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40709739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Detection+of+heat-stable-enterotoxin-producing+Escherichia+coli+by+using+synthetic+oligonucleotides&rft.au=Hill%2C+W+E%3BPayne%2C+W+L%3BZon%2C+G%3BMoseley%2C+S+L&rft.aulast=Hill&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. P 36 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mold flora of fresh tomatoes and presence of tenuazonic acid AN - 40709536; 0843734 AU - Bruce, V R AU - Mislivec, P B AU - Stack, ME Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40709536?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Mold+flora+of+fresh+tomatoes+and+presence+of+tenuazonic+acid&rft.au=Bruce%2C+V+R%3BMislivec%2C+P+B%3BStack%2C+ME&rft.aulast=Bruce&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. P 29 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Improved method for the purification of Campylobacter toxin AN - 40709232; 0847546 AU - McCardell, BA AU - Madden, J M AU - Lee, E C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40709232?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Improved+method+for+the+purification+of+Campylobacter+toxin&rft.au=McCardell%2C+BA%3BMadden%2C+J+M%3BLee%2C+E+C&rft.aulast=McCardell&rft.aufirst=BA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. B 121 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Fungal metabolism and detoxification of 1-nitropyrene AN - 40708762; 0840298 AU - Cerniglia, CE AU - Freeman, J P AU - Miller, D W AU - White, G AU - Heflich, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40708762?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Fungal+metabolism+and+detoxification+of+1-nitropyrene&rft.au=Cerniglia%2C+CE%3BFreeman%2C+J+P%3BMiller%2C+D+W%3BWhite%2C+G%3BHeflich%2C+R&rft.aulast=Cerniglia&rft.aufirst=CE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. O 7 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Aeromonas hydrophila in shellfish-growing waters: Incidence and medium evaluation AN - 40707449; 0840347 AU - Abeyta, C Jr AU - Kaysner, CA AU - Wekell, M M AU - Peeler, J T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40707449?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Aeromonas+hydrophila+in+shellfish-growing+waters%3A+Incidence+and+medium+evaluation&rft.au=Abeyta%2C+C+Jr%3BKaysner%2C+CA%3BWekell%2C+M+M%3BPeeler%2C+J+T&rft.aulast=Abeyta&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. Q 9 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Method for recovery of poliovirus 1 from 25-gram food samples AN - 40705873; 0845543 AU - Sullivan, R AU - Peeler, J T AU - Larkin, E P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40705873?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Method+for+recovery+of+poliovirus+1+from+25-gram+food+samples&rft.au=Sullivan%2C+R%3BPeeler%2C+J+T%3BLarkin%2C+E+P&rft.aulast=Sullivan&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1985, Abstracts available: American Society for Microbiology, Publication Department,1913 I St. NW, Washington, DC 20006, USA, Paper No. Q 73 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Varicella-zoster virus (VZV)-infection of human lymphocyte subpopulations in vitro AN - 40702969; 0808629 AU - Cooper, E C AU - Vujcic, L AU - Quinnan, G V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL KW - U 1500:BIOCHEMISTRY KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40702969?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Varicella-zoster+virus+%28VZV%29-infection+of+human+lymphocyte+subpopulations+in+vitro&rft.au=Cooper%2C+E+C%3BVujcic%2C+L%3BQuinnan%2C+G+V&rft.aulast=Cooper&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Program and Abstracts of the 24th Interscience Conference on Antimicrobial Agents and Chemotherapy", 1984, ASM Publications Office, 1913 I Street, NW, Washington, DC 20006, USA, ISBN 0-914826-67-0; ISSN 0733-6373; Price: $10.00 Abstract No. 42 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Ozone enhancement of soluble platinum salt asthma in a primate model AN - 40691656; 0753932 AU - Moorman, W J AU - Biagini, R E AU - Lewis, T R AU - Bernstein, IL Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40691656?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Ozone+enhancement+of+soluble+platinum+salt+asthma+in+a+primate+model&rft.au=Khan%2C+A+A&rft.aulast=Khan&rft.aufirst=A&rft.date=2000-01-15&rft.volume=182&rft.issue=2&rft.spage=355&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Letters&rft.issn=03781097&rft_id=info:doi/10.1016%2FS0378-1097%2899%2900609-6 LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1984, Abstracts booklet available: Special Publications Dep., FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, 2 vols.; Price: $25.00 Paper No. 3038 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Metabolic oxidation of carcinogenic arylamines by hepatic microsomes and purified cytochromes P-450 AN - 40691590; 0745632 AU - Hammons, G J AU - Guengerich, F P AU - Weis, C C AU - Kadlubar, F F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40691590?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Metabolic+oxidation+of+carcinogenic+arylamines+by+hepatic+microsomes+and+purified+cytochromes+P-450&rft.au=Hammons%2C+G+J%3BGuengerich%2C+F+P%3BWeis%2C+C+C%3BKadlubar%2C+F+F&rft.aulast=Hammons&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1984, Abstracts booklet available: Special Publications Dep., FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, 2 vols.; Price: $25.00 Paper No. 695 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Genetic control of induction of antinucleolar antibodies by mercuric chloride in mice AN - 40679722; 0751659 AU - Robinson, CJG AU - Egorov, I AU - Balazs, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40679722?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Genetic+control+of+induction+of+antinucleolar+antibodies+by+mercuric+chloride+in+mice&rft.au=Robinson%2C+CJG%3BEgorov%2C+I%3BBalazs%2C+T&rft.aulast=Robinson&rft.aufirst=CJG&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1984, Abstracts booklet available: Special Publications Dep., FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, 2 vols.; Price: $25.00 Paper No. 2354 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of chlorphentermine and phentermine on the enzymatic hydrolysis of dipalmitoyl lecithin AN - 40673200; 0742154 AU - Ma, JYC AU - Ma, JKH AU - Weber, K C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE KW - U 1500:BIOCHEMISTRY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40673200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+chlorphentermine+and+phentermine+on+the+enzymatic+hydrolysis+of+dipalmitoyl+lecithin&rft.au=Ma%2C+JYC%3BMa%2C+JKH%3BWeber%2C+K+C&rft.aulast=Ma&rft.aufirst=JYC&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1984, Abstracts booklet available: Special Publications Dep., FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, 2 vols.; Price: $25.00 Paper No. 234 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Airborne endotoxins in poultry confinement units AN - 40666448; 0706061 AU - Olenchock, SA AU - Jones, W G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40666448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Airborne+endotoxins+in+poultry+confinement+units&rft.au=Olenchock%2C+SA%3BJones%2C+W+G&rft.aulast=Olenchock&rft.aufirst=SA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "American Review of Respiratory Disease", Apr. 1984, American Lung Association, 1740 Broadway, New York, NY 10019, USA, ISSN 0003-0805 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Extracts of airborne grain dusts stimulate interleukin 1(IL-1) production by alveolar macrophages AN - 40660841; 0706035 AU - Lewis, D M AU - Mentnech Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40660841?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Extracts+of+airborne+grain+dusts+stimulate+interleukin+1%28IL-1%29+production+by+alveolar+macrophages&rft.au=Lewis%2C+D+M%3BMentnech&rft.aulast=Lewis&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "American Review of Respiratory Disease", Apr. 1984, American Lung Association, 1740 Broadway, New York, NY 10019, USA, ISSN 0003-0805 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of HPLC as a cleanup technique for analyzing food for contaminants by GC-MS AN - 40658098; 0698410 AU - Luchtefeld, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40658098?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Use+of+HPLC+as+a+cleanup+technique+for+analyzing+food+for+contaminants+by+GC-MS&rft.au=Luchtefeld%2C+R&rft.aulast=Luchtefeld&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts available: "HPLC Book of Abstracts", May 1984, HPLC '84, c/o Prof. Csaba Horvath, Yale University, P.O. Box 2159, Yale Station, New Haven, CT 06520, USA, Price: $30.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Alternative approaches for assessing iron status AN - 40650267; 0683343 AU - Yetley, E A AU - Johnson, C AU - McDowell, M AU - Gable, C B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40650267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Alternative+approaches+for+assessing+iron+status&rft.au=Yetley%2C+E+A%3BJohnson%2C+C%3BMcDowell%2C+M%3BGable%2C+C+B&rft.aulast=Yetley&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in Federation Proceedings (Mar. 1 and Mar. 5), 1984, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstract No. 2224 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of benoxaprofen, diethylcarbamazine or nordihydroguaiaretic acid on isoproterenol-induced ventricular fibrillation in rats AN - 40650152; 0684710 AU - Johnson, G L AU - El-Hage, A AU - Ehrreich, S J AU - Gudbjarnason, S AU - Whitehurst, V AU - Balazs, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40650152?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=report&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2000-01-01&rft.volume=&rft.issue=&rft.spage=654&rft.isbn=&rft.btitle=Healthy+People+2010.+Conference+Edition%3A+Partnerships+for+Health+in+the+New+Millennium.+Held+on+January+24-28%2C+2000.+Volume+2&rft.title=Healthy+People+2010.+Conference+Edition%3A+Partnerships+for+Health+in+the+New+Millennium.+Held+on+January+24-28%2C+2000.+Volume+2&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in Federation Proceedings (Mar. 1 and Mar. 5), 1984, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstract No. 2674 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Short-term effects of soy and zinc deficiency in newly hatched Japanese quail AN - 40649797; 0683630 AU - Fox AU - Tao, S-H AU - Stone, CL AU - Fry, BE Jr AU - Johnson, M L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40649797?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Short-term+effects+of+soy+and+zinc+deficiency+in+newly+hatched+Japanese+quail&rft.au=Fox%3BTao%2C+S-H%3BStone%2C+CL%3BFry%2C+BE+Jr%3BJohnson%2C+M+L&rft.aulast=Fox&rft.aufirst=&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in Federation Proceedings (Mar. 1 and Mar. 5), 1984, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstract No. 2341 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of lung unit and whole lung area-volume relationships AN - 40649608; 0686413 AU - Brancazio, L R AU - Frazer, D G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40649608?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparison+of+lung+unit+and+whole+lung+area-volume+relationships&rft.au=Brancazio%2C+L+R%3BFrazer%2C+D+G&rft.aulast=Brancazio&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in Federation Proceedings (Mar. 1 and Mar. 5), 1984, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstract No. 3205 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cd absorption, retention, excretion and distribution patterns in adult and neonate miniature swine AN - 40648262; 0682104 AU - Sapienza, P AU - Levin, R AU - Ikeda, G AU - Miller, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40648262?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Cd+absorption%2C+retention%2C+excretion+and+distribution+patterns+in+adult+and+neonate+miniature+swine&rft.au=Sapienza%2C+P%3BLevin%2C+R%3BIkeda%2C+G%3BMiller%2C+E&rft.aulast=Sapienza&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in Federation Proceedings (Mar. 1 and Mar. 5), 1984, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstract No. 1734 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effect of several calcium antagonists on contractile responses produced by various agonists on rat aortic ring preparations AN - 40647714; 0680572 AU - Jones, E Jr AU - Jones, JA AU - Sun, CL AU - Garvey, H L AU - Hanig, J P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40647714?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+several+calcium+antagonists+on+contractile+responses+produced+by+various+agonists+on+rat+aortic+ring+preparations&rft.au=Jones%2C+E+Jr%3BJones%2C+JA%3BSun%2C+CL%3BGarvey%2C+H+L%3BHanig%2C+J+P&rft.aulast=Jones&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in Federation Proceedings (Mar. 1 and Mar. 5), 1984, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstract No. 960 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Effects of n-alkanes on cytochrome-P450 activities in rat liver and lung microsomes AN - 40644371; 0681842 AU - Rabovsky, J AU - Judy, D J AU - Pailes, W H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7500:PHARMACOLOGY KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40644371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effects+of+n-alkanes+on+cytochrome-P450+activities+in+rat+liver+and+lung+microsomes&rft.au=Rabovsky%2C+J%3BJudy%2C+D+J%3BPailes%2C+W+H&rft.aulast=Rabovsky&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in Federation Proceedings (Mar. 1 and Mar. 5), 1984, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstract No. 1625 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Computer networking of microbial data in the FDA AN - 40627966; 0623162 AU - Benedict, F AU - Walczak, C AU - Portyrata, D AU - Jones, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40627966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Computer+networking+of+microbial+data+in+the+FDA&rft.au=Benedict%2C+F%3BWalczak%2C+C%3BPortyrata%2C+D%3BJones%2C+V&rft.aulast=Benedict&rft.aufirst=F&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts available: American Society for Microbiology, Publications Department, 1913 I St. NW, Washington, DC 20006, USA, Paper No. X4 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Ability of dialyzable tuberculins to inhibit reactivity of nondialyzable tuberculin AN - 40627901; 0622262 AU - Chaparas, S D AU - Godette, K D AU - Benton, D AU - Holobaugh, P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40627901?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Ability+of+dialyzable+tuberculins+to+inhibit+reactivity+of+nondialyzable+tuberculin&rft.au=Chaparas%2C+S+D%3BGodette%2C+K+D%3BBenton%2C+D%3BHolobaugh%2C+P&rft.aulast=Chaparas&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts available: American Society for Microbiology, Publications Department, 1913 I St. NW, Washington, DC 20006, USA, Paper No. U11 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Expansion of micro-IS to include plasmid coding AN - 40622937; 0623169 AU - Jones, V M AU - Tennover, F AU - Hill, W E AU - Benedict, F A AU - Krichevsky, MI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40622937?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Expansion+of+micro-IS+to+include+plasmid+coding&rft.au=Jones%2C+V+M%3BTennover%2C+F%3BHill%2C+W+E%3BBenedict%2C+F+A%3BKrichevsky%2C+MI&rft.aulast=Jones&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts available: American Society for Microbiology, Publications Department, 1913 I St. NW, Washington, DC 20006, USA, Paper No. X5 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Parvoviruses: thermal resistance AN - 40622530; 0629010 AU - Fassolitis, A C AU - Jones, VI AU - Peeler, J T AU - Larkin, E P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40622530?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Parvoviruses%3A+thermal+resistance&rft.au=Fassolitis%2C+A+C%3BJones%2C+VI%3BPeeler%2C+J+T%3BLarkin%2C+E+P&rft.aulast=Fassolitis&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts available: American Society for Microbiology, Publications Department, 1913 I St. NW, Washington, DC 20006, USA, Paper No. S30 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Detection of Clostridium perfringens enterotoxin in stool specimens and culture supernatants by an enzyme-linked immunosorbent assay AN - 40619832; 0622482 AU - Wimsatt, J C AU - Harmon, S M AU - Shah, D B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40619832?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Detection+of+Clostridium+perfringens+enterotoxin+in+stool+specimens+and+culture+supernatants+by+an+enzyme-linked+immunosorbent+assay&rft.au=Wimsatt%2C+J+C%3BHarmon%2C+S+M%3BShah%2C+D+B&rft.aulast=Wimsatt&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts available: American Society for Microbiology, Publications Department, 1913 I St. NW, Washington, DC 20006, USA, Paper No. C61 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Identification of the gene encoding CMP-N-acetyl-neuraminic acid synthetase from the cloned K1 capsule genes of Escherichia coli AN - 40619363; 0627282 AU - Aaronson, W AU - Vann, W AU - Kotsatos, M AU - Silver, R P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40619363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Identification+of+the+gene+encoding+CMP-N-acetyl-neuraminic+acid+synthetase+from+the+cloned+K1+capsule+genes+of+Escherichia+coli&rft.au=Aaronson%2C+W%3BVann%2C+W%3BKotsatos%2C+M%3BSilver%2C+R+P&rft.aulast=Aaronson&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts available: American Society for Microbiology, Publications Department, 1913 I St. NW, Washington, DC 20006, USA, Paper No. D99 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Food chemicals codex method for mixed tocopherol: 1983 collaborative study AN - 40601817; 0558124 AU - Sheppard, A J AU - Rudolf, T S AU - Shen, C-SJ Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40601817?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Food+chemicals+codex+method+for+mixed+tocopherol%3A+1983+collaborative+study&rft.au=Sheppard%2C+A+J%3BRudolf%2C+T+S%3BShen%2C+C-SJ&rft.aulast=Sheppard&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Chromatographic cleanup procedure for use in confirmation of aflatoxin B sub(1) by negative ion chemical ionization (NICI) mass spectrometry AN - 40599680; 0558265 AU - Diprossimo, V P AU - Abdel-Malek, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40599680?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Chromatographic+cleanup+procedure+for+use+in+confirmation+of+aflatoxin+B+sub%281%29+by+negative+ion+chemical+ionization+%28NICI%29+mass+spectrometry&rft.au=Diprossimo%2C+V+P%3BAbdel-Malek%2C+E&rft.aulast=Diprossimo&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Elemental determination in infant formula by inductively coupled plasma emission spectroscopy: collaborative study AN - 40599306; 0557727 AU - Suddendorf, R F AU - Cook, K K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40599306?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Elemental+determination+in+infant+formula+by+inductively+coupled+plasma+emission+spectroscopy%3A+collaborative+study&rft.au=Suddendorf%2C+R+F%3BCook%2C+K+K&rft.aulast=Suddendorf&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Vitamin A and vitamin E contents of infant formula produced in the United States AN - 40595080; 0557552 AU - Landen, WO Jr AU - Hines, D M AU - Hamill, T W AU - Martin, JI AU - Young, E R AU - Eitenmiller, R R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40595080?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Vitamin+A+and+vitamin+E+contents+of+infant+formula+produced+in+the+United+States&rft.au=Landen%2C+WO+Jr%3BHines%2C+D+M%3BHamill%2C+T+W%3BMartin%2C+JI%3BYoung%2C+E+R%3BEitenmiller%2C+R+R&rft.aulast=Landen&rft.aufirst=WO&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Liquid chromatographic determination of aspartame in dry beverage bases and sweetener tablets with confirmation by thin layer chromatography AN - 40593104; 0557308 AU - Daniels, D H AU - Joe, FL Jr AU - Warner, C R AU - Fazio, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40593104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Liquid+chromatographic+determination+of+aspartame+in+dry+beverage+bases+and+sweetener+tablets+with+confirmation+by+thin+layer+chromatography&rft.au=Daniels%2C+D+H%3BJoe%2C+FL+Jr%3BWarner%2C+C+R%3BFazio%2C+T&rft.aulast=Daniels&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparative collaborative study of the helium lake test and the vacuum leak test using canned foods AN - 40591264; 0557284 AU - Rhea, U S AU - Gilchrist, JE AU - Peeler, J T AU - Shah, D B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40591264?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparative+collaborative+study+of+the+helium+lake+test+and+the+vacuum+leak+test+using+canned+foods&rft.au=Rhea%2C+U+S%3BGilchrist%2C+JE%3BPeeler%2C+J+T%3BShah%2C+D+B&rft.aulast=Rhea&rft.aufirst=U&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Aeromonas hydrophila considered as a food borne pathogen AN - 40590257; 0557418 AU - Tsedt, R M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40590257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Aeromonas+hydrophila+considered+as+a+food+borne+pathogen&rft.au=Tsedt%2C+R+M&rft.aulast=Tsedt&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Lymphocytes from patients with acquired immunodeficiency syndrome suppress alloantigen- but not mitogen-induced responses AN - 40589941; 0551265 AU - Wells, MA AU - Burlington, D B AU - Rook, AH AU - Frederick, W R AU - Masur, H AU - Fauci, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40589941?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Lymphocytes+from+patients+with+acquired+immunodeficiency+syndrome+suppress+alloantigen-+but+not+mitogen-induced+responses&rft.au=Wells%2C+MA%3BBurlington%2C+D+B%3BRook%2C+AH%3BFrederick%2C+W+R%3BMasur%2C+H%3BFauci%2C+A&rft.aulast=Wells&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: ASM, Publications Sales Dep., 1913 I Street, N.W., Washington, DC 20006, USA, Abstracts booklet: ISSN: 0733-6373; Price: $10.00 Abstract No. 957 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Immunogenicity of wild and attenuated varicella zoster virus in rhesus monkeys AN - 40587087; 0547206 AU - Asano, Y AU - Albrecht, P AU - Rastogi, S C AU - Vickers, J H Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40587087?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Immunogenicity+of+wild+and+attenuated+varicella+zoster+virus+in+rhesus+monkeys&rft.au=Asano%2C+Y%3BAlbrecht%2C+P%3BRastogi%2C+S+C%3BVickers%2C+J+H&rft.aulast=Asano&rft.aufirst=Y&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: ASM, Publications Sales Dep., 1913 I Street, N.W., Washington, DC 20006, USA, Abstracts booklet: ISSN: 0733-6373; Price: $10.00 Abstract No. 398 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Automated characterization of particles extracted from human lungs: three cases of tungsten carbide exposure AN - 40586704; 0565823 AU - Stettler, LE AU - Groth, D H AU - Platek, S F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 8000:PHYSICS AND ASTRONOMY UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40586704?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Automated+characterization+of+particles+extracted+from+human+lungs%3A+three+cases+of+tungsten+carbide+exposure&rft.au=Stettler%2C+LE%3BGroth%2C+D+H%3BPlatek%2C+S+F&rft.aulast=Stettler&rft.aufirst=LE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Proceedings in: "Scanning Electron Microscopy/1983/I-III", 1983, Scanning Electron Microscopy, Inc., P.O. Box 66507, AMF O'Hare (Chicago), IL 60666 USA, ISSN 0586-5581. Proceedings consists of 3 issues N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Coprostanol: a promising indicator of fecal contamination of food AN - 40582927; 0557109 AU - Hoskin, G P AU - Bandler, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:ANIMAL AND PLANT SCIENCE KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40582927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Coprostanol%3A+a+promising+indicator+of+fecal+contamination+of+food&rft.au=Hoskin%2C+G+P%3BBandler%2C+R&rft.aulast=Hoskin&rft.aufirst=G&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: AOAC, 1111 N. 19th St., Suite 210, Arlington, VA 22209, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Occurrence of Tn917-mediated MLS resistance among group D streptococci isolated from swine, broilers, and humans AN - 40578822; 0546687 AU - Rollins, L D AU - Lee, L N AU - Banai, M AU - Leblanc, D J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40578822?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Occurrence+of+Tn917-mediated+MLS+resistance+among+group+D+streptococci+isolated+from+swine%2C+broilers%2C+and+humans&rft.au=Rollins%2C+L+D%3BLee%2C+L+N%3BBanai%2C+M%3BLeblanc%2C+D+J&rft.aulast=Rollins&rft.aufirst=L&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: ASM, Publications Sales Dep., 1913 I Street, N.W., Washington, DC 20006, USA, Abstracts booklet: ISSN: 0733-6373; Price: $10.00 Abstract No. 248 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Transfer of maternal varicella-zoster virus antibody to the infant and its persistence during the first two years of life AN - 40576618; 0550194 AU - Asano, Y AU - Tsuruta, M AU - Albrecht, P AU - Vujcic, L K AU - Quinnan, G V AU - Pass, B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40576618?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Transfer+of+maternal+varicella-zoster+virus+antibody+to+the+infant+and+its+persistence+during+the+first+two+years+of+life&rft.au=Asano%2C+Y%3BTsuruta%2C+M%3BAlbrecht%2C+P%3BVujcic%2C+L+K%3BQuinnan%2C+G+V%3BPass%2C+B&rft.aulast=Asano&rft.aufirst=Y&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts booklet available: ASM, Publications Sales Dep., 1913 I Street, N.W., Washington, DC 20006, USA, Abstracts booklet: ISSN: 0733-6373; Price: $10.00 Abstract No. 731 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Strain differences in induction of antinuclear antibodies by mercuric chloride, gold sodium thiomalate, and D-penicillamine in inbred mice AN - 40573129; 0479598 AU - Robinson, CJG AU - Egorov, I AU - Balazs, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40573129?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Strain+differences+in+induction+of+antinuclear+antibodies+by+mercuric+chloride%2C+gold+sodium+thiomalate%2C+and+D-penicillamine+in+inbred+mice&rft.au=Robinson%2C+CJG%3BEgorov%2C+I%3BBalazs%2C+T&rft.aulast=Robinson&rft.aufirst=CJG&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Characterization of Langerhans-like cells isolated from mouse epidermis AN - 40562243; 0474290 AU - Hellman, K B AU - Schuller, G B AU - Roe, J L AU - Fowler, A K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40562243?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Characterization+of+Langerhans-like+cells+isolated+from+mouse+epidermis&rft.au=Hellman%2C+K+B%3BSchuller%2C+G+B%3BRoe%2C+J+L%3BFowler%2C+A+K&rft.aulast=Hellman&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of chronic doxorubicin cardiotoxicity in SHR and normotensive rats AN - 40561891; 0461301 AU - Herman, E AU - El-Hage, A AU - Ferrans, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40561891?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparison+of+chronic+doxorubicin+cardiotoxicity+in+SHR+and+normotensive+rats&rft.au=Herman%2C+E%3BEl-Hage%2C+A%3BFerrans%2C+V&rft.aulast=Herman&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cadmium inhibition of calcium fluxes in duodenum of the rat AN - 40556859; 0480404 AU - Toraason, M AU - Foulkes, E C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40556859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Cadmium+inhibition+of+calcium+fluxes+in+duodenum+of+the+rat&rft.au=Toraason%2C+M%3BFoulkes%2C+E+C&rft.aulast=Toraason&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Immunotoxicological study of isobutyl nitrite AN - 40554783; 0474180 AU - Lewis, D M AU - Koller, WA AU - Lynch, D W Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40554783?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Immunotoxicological+study+of+isobutyl+nitrite&rft.au=Lewis%2C+D+M%3BKoller%2C+WA%3BLynch%2C+D+W&rft.aulast=Lewis&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Incorporation of ( super(3)H)palmitate into disaturated phosphatidylcholines in rat alveolar macrophages AN - 40554463; 0480563 AU - Miles, PR AU - Bowman, L AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40554463?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Incorporation+of+%28+super%283%29H%29palmitate+into+disaturated+phosphatidylcholines+in+rat+alveolar+macrophages&rft.au=Miles%2C+PR%3BBowman%2C+L%3BCastranova%2C+V&rft.aulast=Miles&rft.aufirst=PR&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Assessment of vitamin and mineral supplement usage by means of a telephone survey AN - 40550938; 0464558 AU - McDonald, J T AU - Stewart, M L AU - Schucker, R E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40550938?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Assessment+of+vitamin+and+mineral+supplement+usage+by+means+of+a+telephone+survey&rft.au=McDonald%2C+J+T%3BStewart%2C+M+L%3BSchucker%2C+R+E&rft.aulast=McDonald&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cardiotoxic effects of a combination of caffeine and isoproterenol AN - 40543700; 0466920 AU - Vick, J AU - Joseph, X AU - Whitehurst, V AU - Balazs, T AU - Herman, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40543700?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Cardiotoxic+effects+of+a+combination+of+caffeine+and+isoproterenol&rft.au=Vick%2C+J%3BJoseph%2C+X%3BWhitehurst%2C+V%3BBalazs%2C+T%3BHerman%2C+E&rft.aulast=Vick&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "Federation Proceedings", Mar. 1983, FASEB Special Publications Office, 9650 Rockville Pike, Bethesda, MD 20814, USA, Abstracts in a 3 vol. set. Price: $40.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Qualitative screening of airborne contaminants at hazardous waste sites AN - 40526640; 0390560 AU - Geraci, CL AU - Costello, R J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2500:CHEMISTRY AND CHEMICAL ENGINEERING UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40526640?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Qualitative+screening+of+airborne+contaminants+at+hazardous+waste+sites&rft.au=Geraci%2C+CL%3BCostello%2C+R+J&rft.aulast=Geraci&rft.aufirst=CL&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For information please contact: American Chemical Society, A.T. Winstead, 1155 16th St. NW, Washington, DC 20036, USA N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Issues concerning the use of potassium iodide as a thyroid-blocking agent in a radiation accident AN - 40526077; 0388792 AU - Shleien, B AU - Halperin, JA AU - Bilstad, J M AU - Kahana, S AU - Dutra, EV Jr Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 3500:CLINICAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40526077?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Issues+concerning+the+use+of+potassium+iodide+as+a+thyroid-blocking+agent+in+a+radiation+accident&rft.au=Shleien%2C+B%3BHalperin%2C+JA%3BBilstad%2C+J+M%3BKahana%2C+S%3BDutra%2C+EV+Jr&rft.aulast=Shleien&rft.aufirst=B&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: Health Physics, Jul. 1982, Pergamon Press, Fairview Park, Elmsford, NY 10523, USA, Abstract No. P/305 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Production of monoclonal antibodies to staphylococcal enterotoxins A and D AN - 40521768; 0394368 AU - Meyer, R F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40521768?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Production+of+monoclonal+antibodies+to+staphylococcal+enterotoxins+A+and+D&rft.au=Meyer%2C+R+F&rft.aulast=Meyer&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For information please contact: American Society for Microbiology, 1913 I St. NW, Washington, DC 20006 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Limulus amoebocyte lysate test as an indicator of coliform density in foods AN - 40518317; 0397804 AU - Smith, A M AU - Hebert, W O AU - Zapatka, F A AU - Hamdy, M K Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40518317?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Skousen%2C+Jeff%3BPerry%2C+Eric%3BLeavitt%2C+Bruce%3BSames%2C+Gary%3BChisholm%2C+William%3BCecil%2C+C+Blaine%3BHammack%2C+Richard&rft.aulast=Skousen&rft.aufirst=Jeff&rft.date=2000-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Static+tests+for+coal+mining+acid+mine+drainage+prediction+in+the+Eastern+U.S.&rft.title=Static+tests+for+coal+mining+acid+mine+drainage+prediction+in+the+Eastern+U.S.&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For information please contact: American Society for Microbiology, 1913 I St. NW, Washington, DC 20006 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Interaction of benzyl alcohol and bacterial endotoxins: Enhanced toxicity due to combined intravenous administration AN - 40516545; 0401449 AU - Cebula, T A AU - El-Hage, A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40516545?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Interaction+of+benzyl+alcohol+and+bacterial+endotoxins%3A+Enhanced+toxicity+due+to+combined+intravenous+administration&rft.au=Cebula%2C+T+A%3BEl-Hage%2C+A&rft.aulast=Cebula&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For information please contact: American Society for Microbiology, 1913 I St. NW, Washington, DC 20006 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Stimulation of in vivo poliovirus RNA synthesis by inhibitors of protein synthesis AN - 40514526; 0387411 AU - Lundquist, R E AU - Dunlap, R C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40514526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Stimulation+of+in+vivo+poliovirus+RNA+synthesis+by+inhibitors+of+protein+synthesis&rft.au=Lundquist%2C+R+E%3BDunlap%2C+R+C&rft.aulast=Lundquist&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For information please contact: American Society for Microbiology, 1913 I St. NW, Washington, DC 20006 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Use of a computer-controlled microscope photometer to quantitatively analyze intensity images of immunofluorescent cells AN - 40514028; 0388955 AU - Kaplan, D S AU - Picciolo, G L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40514028?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Use+of+a+computer-controlled+microscope+photometer+to+quantitatively+analyze+intensity+images+of+immunofluorescent+cells&rft.au=Kaplan%2C+D+S%3BPicciolo%2C+G+L&rft.aulast=Kaplan&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For information please contact: American Society for Microbiology, 1913 I St. NW, Washington, DC 20006 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Metabolism of 1-methylnaphthalene and 2-methylnaphthalene by the filamentous fungus Cunninghamella elegans AN - 40513504; 0401773 AU - Cerniglia, CE AU - Lambert, K J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40513504?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Metabolism+of+1-methylnaphthalene+and+2-methylnaphthalene+by+the+filamentous+fungus+Cunninghamella+elegans&rft.au=Cerniglia%2C+CE%3BLambert%2C+K+J&rft.aulast=Cerniglia&rft.aufirst=CE&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: For information please contact: American Society for Microbiology, 1913 I St. NW, Washington, DC 20006 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Improved Yield of High Molecular Weight Retrovirus RNA AN - 40466801; 0285516 AU - Park, J J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40466801?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Improved+Yield+of+High+Molecular+Weight+Retrovirus+RNA&rft.au=Park%2C+J+J&rft.aulast=Park&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Proceedings in: "Developments in Industrial Microbiology", May 1983, Society for Industrial Microbiology, 1401 Wilson Blvd., Arlington, VA 22209, L.C. No. 60-13953; ISSN 0070-4563; Price $34.95 + postage N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Specificity of Protection Against Influenza Virus Infection by Cytotoxic T Lymphocytes in Mice AN - 40460392; 0268929 AU - Wells, MA AU - Daniel, S AU - Kiley, S C AU - Ennis, F A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40460392?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Specificity+of+Protection+Against+Influenza+Virus+Infection+by+Cytotoxic+T+Lymphocytes+in+Mice&rft.au=Wells%2C+MA%3BDaniel%2C+S%3BKiley%2C+S+C%3BEnnis%2C+F+A&rft.aulast=Wells&rft.aufirst=MA&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: 1982, Program and abstracts book available: American Society for Microbiology, 1913 I St. NW, Washington, DC 20006, ISBN 0-914826-44-1; 182 pages; Price: $10 Poster PV:7 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of 111 In-Labeled Leukocytes for Imaging of Experimental Myocarditis AN - 40458575; 0246007 AU - Mantil, J C AU - Fernandez, M AU - Lukes, S AU - van der Bel-Kahn, J AU - Mayfield, G AU - Gerson, M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40458575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Evaluation+of+111+In-Labeled+Leukocytes+for+Imaging+of+Experimental+Myocarditis&rft.au=Mantil%2C+J+C%3BFernandez%2C+M%3BLukes%2C+S%3Bvan+der+Bel-Kahn%2C+J%3BMayfield%2C+G%3BGerson%2C+M&rft.aulast=Mantil&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Abstracts in: "The Journal of Nuclear Medicine", May 1982, Society of Nuclear Medicine, 475 Park Avenue South, New York, NY 10016, Abstracts also available in booklet form N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Comparison of Virulence and Immunogenicity of Towne Strain and a Low-Passage (Toledo-1 Strain) Isolate of Human Cytomegalovirus AN - 40458170; 0274240 AU - Frederick, W AU - Rook, A AU - Delery, M AU - Epstein, J AU - Ramsey, K AU - Manischewitz, J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:BIOLOGY GENERAL KW - U 4500:EXPERIMENTAL MEDICINE UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40458170?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Comparison+of+Virulence+and+Immunogenicity+of+Towne+Strain+and+a+Low-Passage+%28Toledo-1+Strain%29+Isolate+of+Human+Cytomegalovirus&rft.au=Frederick%2C+W%3BRook%2C+A%3BDelery%2C+M%3BEpstein%2C+J%3BRamsey%2C+K%3BManischewitz%2C+J&rft.aulast=Frederick&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: In "Program and Abstracts of the 22nd Interscience Conference on Antimicrobial Agents and Chemotherapy", 1982, American Society for Microbiology, 1913 I St., NW, Washington, DC 20006 USA, Abstracts and program booklet $10.00 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Folic acid in enriched cereal-grain products by immunoassay AN - 39309480; 3547013 AU - Rader, JI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39309480?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Folic+acid+in+enriched+cereal-grain+products+by+immunoassay&rft.au=Rader%2C+JI&rft.aulast=Rader&rft.aufirst=JI&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Amercian Association of Cereal Chemists, 3340 Pilot Knob Road, St. Paul, MN 55121-2097, USA; fax: 651 454 07661; email: aacc@scisoc.org N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Role of tumor necrosis factor (TNF) in airway reactivity to toluene diisocyanate (TDI) AN - 39268114; 3524646 AU - Matheson, J M AU - Lange, R W AU - Lemus, R AU - Karol, M H AU - Luster, MI Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39268114?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Role+of+tumor+necrosis+factor+%28TNF%29+in+airway+reactivity+to+toluene+diisocyanate+%28TDI%29&rft.au=Matheson%2C+J+M%3BLange%2C+R+W%3BLemus%2C+R%3BKarol%2C+M+H%3BLuster%2C+MI&rft.aulast=Matheson&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Rapid determination of total trans fat content by attenuated total reflection infrared spectroscopy: An international collaborative study AN - 39261226; 3523909 AU - Mossoba, M M AU - Adam, M AU - Lee, T Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39261226?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Rapid+determination+of+total+trans+fat+content+by+attenuated+total+reflection+infrared+spectroscopy%3A+An+international+collaborative+study&rft.au=Mossoba%2C+M+M%3BAdam%2C+M%3BLee%2C+T&rft.aulast=Mossoba&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Oil Chemists' Society, AOCS Meetings and Exhibits Department, P.O. Box 3489, Champaign, Il 61826-3489, USA; phone: 1-217-359-2344; fax: 1-217-351-8091; email: meetings@aocs.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Effect of D-amphetamine on extracellular glutamate and aspartate levels in rat amygdaloid microdialysate AN - 39217038; 3524800 AU - Tor-Agbidye, J AU - Yamamoto, B K AU - Bowyer, J F Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39217038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Effect+of+D-amphetamine+on+extracellular+glutamate+and+aspartate+levels+in+rat+amygdaloid+microdialysate&rft.au=Tor-Agbidye%2C+J%3BYamamoto%2C+B+K%3BBowyer%2C+J+F&rft.aulast=Tor-Agbidye&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Trimethyltin and LPS induce distinct patterns of cytokine and chemokine expression in rat hippocampus: Lack of an association with injury-induced gliosis AN - 39217017; 3524795 AU - Little, A R AU - O'Callaghan, J P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39217017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Trimethyltin+and+LPS+induce+distinct+patterns+of+cytokine+and+chemokine+expression+in+rat+hippocampus%3A+Lack+of+an+association+with+injury-induced+gliosis&rft.au=Little%2C+A+R%3BO%27Callaghan%2C+J+P&rft.aulast=Little&rft.aufirst=A&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Operation and maintenance of rural drinking water supply systems in Honduras: Factors influencing long-term performance AN - 39210548; 3521473 AU - Gelting, R Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1200:Aquatic Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39210548?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Operation+and+maintenance+of+rural+drinking+water+supply+systems+in+Honduras%3A+Factors+influencing+long-term+performance&rft.au=Gelting%2C+R&rft.aulast=Gelting&rft.aufirst=R&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: NSF International, Center for Public Information at, NSF International, Ann Arbor, MI 48105, USA; phone: 734 827 6888; fax: 734 827 6840; email: raeder@nsf.org; URL: www.nsf.org. Paper No. 5C-5 N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Versatile, portable and low cost computerized data logging and charting system compatible with electronic charts AN - 39210324; 3498287 AU - Pirillo, P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39210324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Versatile%2C+portable+and+low+cost+computerized+data+logging+and+charting+system+compatible+with+electronic+charts&rft.au=Pirillo%2C+P&rft.aulast=Pirillo&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Marine Technology Society (MTS), 1828 L Street NW, Suite 906, Washington, D.C. 20036, USA; phone: 202-775-5966; email: 75112.2154@compuserve.com; URL: http://www.selectsite.com/oceans95/mts/, Full papers available. Contact MTS for price. Poster Paper N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Latex allergy in the workplace AN - 39204210; 3525169 AU - Toraason, M AU - Germolec, D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39204210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Latex+allergy+in+the+workplace&rft.au=Toraason%2C+M%3BGermolec%2C+D&rft.aulast=Toraason&rft.aufirst=M&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Antibodies targeting fusion-active structures in HIV-1 gp411 AN - 39200980; 3500851 AU - De Rosny, E Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39200980?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Antibodies+targeting+fusion-active+structures+in+HIV-1+gp411&rft.au=De+Rosny%2C+E&rft.aulast=De+Rosny&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Institute for Human Virology, 725 West Lombard Street, Baltimore, MD 21201, USA; phone: 410-706-8614; email: valuckas@umbi.umd.edu; URL: www.ihv.org, Abstracts available. Contact IHV for price. N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Risk assessment-based approach for the biological evaluation of medical device materials AN - 39198924; 3524604 AU - Stratmeyer, ME AU - Brown, R P Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39198924?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Risk+assessment-based+approach+for+the+biological+evaluation+of+medical+device+materials&rft.au=Stratmeyer%2C+ME%3BBrown%2C+R+P&rft.aulast=Stratmeyer&rft.aufirst=ME&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Animal models and mechanisms of latex allergy AN - 39194325; 3525173 AU - Meade, B J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39194325?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Animal+models+and+mechanisms+of+latex+allergy&rft.au=Meade%2C+B+J&rft.aulast=Meade&rft.aufirst=B&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Vitamin E deficiency increases susceptibility of the Balb/C mouse to MDMA-induced dopaminergic neurotoxicity AN - 39193615; 3524798 AU - Johnson, E A AU - Shvedova, A A AU - Kisin, E AU - O'Callaghan, J P AU - Kommineni, C AU - Miller, D B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39193615?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Vitamin+E+deficiency+increases+susceptibility+of+the+Balb%2FC+mouse+to+MDMA-induced+dopaminergic+neurotoxicity&rft.au=Johnson%2C+E+A%3BShvedova%2C+A+A%3BKisin%2C+E%3BO%27Callaghan%2C+J+P%3BKommineni%2C+C%3BMiller%2C+D+B&rft.aulast=Johnson&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Activation of activator protein-1 by reactive oxygen species associated with asbestos AN - 39187996; 3525759 AU - Vallyathan, V AU - Ding, M AU - Shi, X AU - Castranova, V Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39187996?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Activation+of+activator+protein-1+by+reactive+oxygen+species+associated+with+asbestos&rft.au=Vallyathan%2C+V%3BDing%2C+M%3BShi%2C+X%3BCastranova%2C+V&rft.aulast=Vallyathan&rft.aufirst=V&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Phosphodiesterase type III (PDE III) inhibitor induces vasculitis preceded by apoptosis in mesenteric vessels and lymphoid tissues in rats AN - 39187265; 3525623 AU - Zhang, J AU - Herman, E H AU - Weaver, J L AU - Chadwick, D P AU - Broud, D AU - Rosenzweig, BA AU - Knapton, AD AU - Whitehurst, V E AU - Sistare, F D Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39187265?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Phosphodiesterase+type+III+%28PDE+III%29+inhibitor+induces+vasculitis+preceded+by+apoptosis+in+mesenteric+vessels+and+lymphoid+tissues+in+rats&rft.au=Zhang%2C+J%3BHerman%2C+E+H%3BWeaver%2C+J+L%3BChadwick%2C+D+P%3BBroud%2C+D%3BRosenzweig%2C+BA%3BKnapton%2C+AD%3BWhitehurst%2C+V+E%3BSistare%2C+F+D&rft.aulast=Zhang&rft.aufirst=J&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Redox-cycling of phenols causes depletion of GSH, oxidative stress and cytotoxicity in normal human epidermal keratinocytes (NHEKS) AN - 39186325; 3525385 AU - Kisin, E R AU - Kommineni, C AU - Tyurina, Y Y AU - Tyurin, V A AU - Schwegler-Berry, D AU - Castranova, V AU - Kagan, V E AU - Shvedova, A A Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39186325?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Redox-cycling+of+phenols+causes+depletion+of+GSH%2C+oxidative+stress+and+cytotoxicity+in+normal+human+epidermal+keratinocytes+%28NHEKS%29&rft.au=Kisin%2C+E+R%3BKommineni%2C+C%3BTyurina%2C+Y+Y%3BTyurin%2C+V+A%3BSchwegler-Berry%2C+D%3BCastranova%2C+V%3BKagan%2C+V+E%3BShvedova%2C+A+A&rft.aulast=Kisin&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Safety risk assessment of the mycotoxin patulin in apple juice and apple juice products AN - 39186059; 3525280 AU - Henry, SH AU - DiNovi, MJ AU - Bolger, P M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39186059?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Safety+risk+assessment+of+the+mycotoxin+patulin+in+apple+juice+and+apple+juice+products&rft.au=Henry%2C+SH%3BDiNovi%2C+MJ%3BBolger%2C+P+M&rft.aulast=Henry&rft.aufirst=SH&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 AN - 39185845; 3517311 AU - Shacter, E AU - Lee, Y-J Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39185845?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Hydrogen+peroxide+inhibits+activation%2C+not+activity%2C+of+cellular+caspase-3&rft.au=Shacter%2C+E%3BLee%2C+Y-J&rft.aulast=Shacter&rft.aufirst=E&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Elsevier Science, Inc., 655 Avenue of the Americas, New York, NY 10010-5107; phone: 212-633-3730; fax: 212-633-3680; email: usinfo-f@elsevier.com; URL: www.elsevier.com, Full Abstracts Available. N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Assessment of DNA damage in workers exposed to roofing asphalt AN - 39184850; 3525073 AU - Reid, T AU - Hayden, C AU - Marlow, D AU - Rinehart, R AU - Mierz, J AU - Werren, D AU - Toraason, M AU - DeBord, D G Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39184850?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Assessment+of+DNA+damage+in+workers+exposed+to+roofing+asphalt&rft.au=Reid%2C+T%3BHayden%2C+C%3BMarlow%2C+D%3BRinehart%2C+R%3BMierz%2C+J%3BWerren%2C+D%3BToraason%2C+M%3BDeBord%2C+D+G&rft.aulast=Reid&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Distribution of 2,4-dichlorophenoxyacetic acid (2,4-D) in the rat after low-dose, chronic administration AN - 39183828; 3524522 AU - Patterson, T A AU - Slikker, W Jr AU - Binienda, Z AU - Duhart, H AU - Lipe, G AU - Newport, G AU - Sandberg, JA AU - Kim, C S Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39183828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Distribution+of+2%2C4-dichlorophenoxyacetic+acid+%282%2C4-D%29+in+the+rat+after+low-dose%2C+chronic+administration&rft.au=Patterson%2C+T+A%3BSlikker%2C+W+Jr%3BBinienda%2C+Z%3BDuhart%2C+H%3BLipe%2C+G%3BNewport%2C+G%3BSandberg%2C+JA%3BKim%2C+C+S&rft.aulast=Patterson&rft.aufirst=T&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Evaluation of a FitCheck hearing protector test system AN - 39181022; 3511290 AU - Murphy, W J AU - Franks, J R AU - Harris, DA Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1200:Aquatic Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39181022?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Evaluation+of+a+FitCheck+hearing+protector+test+system&rft.au=Murphy%2C+W+J%3BFranks%2C+J+R%3BHarris%2C+DA&rft.aulast=Murphy&rft.aufirst=W&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Acoustical Society of America, Suite 1, Number 1, 2 Huntington Quadrangle, Melville, NY 11747-4502, USA; phone: 516-576-2360; email: asa@aip.org; URL: asa.aip.org, Abstracts available. Price $100. N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - USFDA/NIEHS phototoxicology research center: Understanding and developing animal models for photocarcinogenesis testing AN - 39179008; 3525631 AU - Howard, P C AU - Sams, R L AU - Miller, B J AU - Wamer, W G AU - Beer, J Z Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39179008?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=USFDA%2FNIEHS+phototoxicology+research+center%3A+Understanding+and+developing+animal+models+for+photocarcinogenesis+testing&rft.au=Howard%2C+P+C%3BSams%2C+R+L%3BMiller%2C+B+J%3BWamer%2C+W+G%3BBeer%2C+J+Z&rft.aulast=Howard&rft.aufirst=P&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Animal models and consideration of immune system development AN - 39178106; 3526348 AU - Hastings, K L Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39178106?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Animal+models+and+consideration+of+immune+system+development&rft.au=Hastings%2C+K+L&rft.aulast=Hastings&rft.aufirst=K&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - LC/MS confirmation of animal drug residues for regulatory use AN - 39168851; 3491514 AU - Turnipseed, S B AU - Gonzales, SA AU - Pfenning, A P AU - Roybal, J B Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 5500:Geoscience UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39168851?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=LC%2FMS+confirmation+of+animal+drug+residues+for+regulatory+use&rft.au=Turnipseed%2C+S+B%3BGonzales%2C+SA%3BPfenning%2C+A+P%3BRoybal%2C+J+B&rft.aulast=Turnipseed&rft.aufirst=S&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: Milestone Presentations, 4255 S. Buckley Road, Suite 118, Aurora, CO 80013, USA; phone: 800-996-3233; fax: 303-690-3233; email: milestone@bod.net; URL: www.milestoneshows.com, Abstracts available. Price $25. Paper No. 210 N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Exposure to silica activates macrophages and increases the pulmonary clearance of listeria monocytogenes in rats AN - 39166444; 3525966 AU - Yang, H AU - Ma, JYC AU - Roberts, J R AU - Barger, M W AU - Butterworth, L AU - Castranova, V AU - Antonini, J M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 1000:Animal and Plant Science KW - U 4300: Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39166444?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Exposure+to+silica+activates+macrophages+and+increases+the+pulmonary+clearance+of+listeria+monocytogenes+in+rats&rft.au=Yang%2C+H%3BMa%2C+JYC%3BRoberts%2C+J+R%3BBarger%2C+M+W%3BButterworth%2C+L%3BCastranova%2C+V%3BAntonini%2C+J+M&rft.aulast=Yang&rft.aufirst=H&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: The Society of Toxicology, 1767 Business Center Drive, Suite 302, Reston, VA 20190-5332, USA; phone: (703) 438-3115; fax: (703) 438-3113; email: sothq@toxicology.org; URL: www.toxicology.org N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - U.S. regulatory perspective for prion issues AN - 39158605; 3499975 AU - Asher, D M Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 2000:Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39158605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=U.S.+regulatory+perspective+for+prion+issues&rft.au=Asher%2C+D+M&rft.aulast=Asher&rft.aufirst=D&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: IBC USA, 225 Turnpike Road, Southborough, MA 01772-1749, USA; phone: 508-481-6400; email: inq@ibcusa.com; URL: www.ibcusa.com/2407, Abstracts available. Price $195 (plus S&H). N1 - Last updated - 2011-10-26 ER - TY - CPAPER T1 - Human health and ecologic impacts of DDT AN - 39152090; 3517726 AU - DeRosa, C Y1 - 2000/12/31/ PY - 2000 DA - 2000 Dec 31 KW - CPI, Conference Papers Index KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/39152090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Human+health+and+ecologic+impacts+of+DDT&rft.au=DeRosa%2C+C&rft.aulast=DeRosa&rft.aufirst=C&rft.date=2000-12-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - SuppNotes - Availability: American Association for the Advancement of Science, 1333 H St., NW, 8th Floor, Washington, DC 20005, USA; URL: www.aaas.org, Titles are taken from selected sections of the larger conference. N1 - Last updated - 2011-10-26 ER - TY - JOUR T1 - Risk assessment used to evaluate the US position on Listeria monocytogenes in seafood. AN - 72532185; 11156269 AB - Human listeriosis has been associated with consumption of food including seafood. Surveillance information on the presence of Listeria monocytogenes in seafood products is presented as a background for steps that are being taken to inform risk managers of risks associated with particular food products. United States policy for L. monocytogenes in food has been shaped by our increasing knowledge of the epidemiology of outbreaks and sporadic cases of human listeriosis, the potentially severe public health consequences, and the characteristics of the organism. A quantitative risk assessment of the scientific knowledge we have about the organism and the epidemiology of listeriosis should be the basis for changes in this policy. Risk assessment uses quantitative scientific and epidemiological information in a structured format to determine the risks associated with particular hazards. A quantitative risk assessment is being performed using currently available data by the US Food and Drug Administration, in collaboration with the US Food Safety and Inspection Service, to determine the risk of listeriosis from various foods, including seafood, for specific intervention methods, and for general and at-risk population groups. The questions being considered include those on level of consumption, epidemiology, dose response, and the virulence, biology, and ecology of the organism. Risk managers can use the resulting information to form a defendable science-based policy on L. monocytogenes in food. JF - International journal of food microbiology AU - Elliot, E L AU - Kvenberg, J E AD - Food and Drug Administration, Center for Food Safety and Applied Nutrition, Washington, DC 20204, USA. eelliot@cfsan.fda.gov Y1 - 2000/12/20/ PY - 2000 DA - 2000 Dec 20 SP - 253 EP - 260 VL - 62 IS - 3 SN - 0168-1605, 0168-1605 KW - Index Medicus KW - Animals KW - Humans KW - Public Policy KW - United States -- epidemiology KW - Risk Assessment KW - Listeriosis -- epidemiology KW - Listeria monocytogenes -- isolation & purification KW - Listeria monocytogenes -- growth & development KW - Food Microbiology -- legislation & jurisprudence KW - Disease Outbreaks -- prevention & control KW - Listeriosis -- prevention & control KW - Seafood -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72532185?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+food+microbiology&rft.atitle=Risk+assessment+used+to+evaluate+the+US+position+on+Listeria+monocytogenes+in+seafood.&rft.au=Elliot%2C+E+L%3BKvenberg%2C+J+E&rft.aulast=Elliot&rft.aufirst=E&rft.date=2000-12-20&rft.volume=62&rft.issue=3&rft.spage=253&rft.isbn=&rft.btitle=&rft.title=International+journal+of+food+microbiology&rft.issn=01681605&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-05-17 N1 - Date created - 2001-01-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Identification of mucAB-like homologs on two IncT plasmids, R394 and Rts-1. AN - 72461933; 11106794 AB - Recent phylogenetic analysis of the superfamily of lesion-replicating DNA polymerases suggest that they can be broadly divided into four sub-groups comprised of UmuC-like, DinB-like, Rev1-like and Rad30-like proteins. The UmuC-like sub-family is best characterized at the genetic level and sequence analysis of eleven umu orthologs, residing on bacterial chromosomes or on self-transmissible R-plasmids allows further subdivision into five sub-groups (UmuDC, MucAB, ImpAB, RumAB and RulAB) based on amino acid sequence conservation. Some of these orthologs are apparently inactive in situ, but may promote increased mutagenesis and survival when subcloned and expressed from high-copy number plasmids. We were, therefore, interested in devising an assay that would identify umuC-like genes in situ in the absence of a functional assay. To this end, degenerate primers directed towards conserved amino acid regions within the UmuC-like sub-family of DNA polymerases were designed and used to identify mucAB-like operons on the IncT plasmids, R394 and Rts-1.Interestingly, DNA sequence analysis of an approximately 7kb region of R394 identified two LexA-regulated genes immediately downstream of mucAB((R394)) that are similar to the chromosomally-encoded Escherichia coli tus gene and the IncI plasmid-encoded impC gene, respectively. Analysis of the R394 and Rts-1 mucB genes revealed that both contain insertions which result in the expression of a truncated inactive MucB protein. While R394 was unable to restore mutagenesis functions to a DeltaumuDC E. coli strain, Rts-1 surprisingly promoted significant levels of MMS-induced SOS mutagenesis, raising the possibility that Rts-1 encodes another, yet unidentified, umu-like homolog. JF - Mutation research AU - Koch, W H AU - Fernández de Henestrosa, A R AU - Woodgate, R AD - Molecular Biology Branch, Food and Drug Administration, 20204, Washington, DC, USA. Y1 - 2000/12/20/ PY - 2000 DA - 2000 Dec 20 SP - 1 EP - 13 VL - 457 IS - 1-2 SN - 0027-5107, 0027-5107 KW - Bacterial Proteins KW - 0 KW - DNA Primers KW - DNA, Bacterial KW - Escherichia coli Proteins KW - ImpC protein, Bacteria KW - LexA protein, Bacteria KW - mucAB protein, E coli KW - 138186-81-9 KW - UmuC protein, E coli KW - 98059-80-4 KW - Methyl Methanesulfonate KW - AT5C31J09G KW - DNA-Directed DNA Polymerase KW - EC 2.7.7.7 KW - Serine Endopeptidases KW - EC 3.4.21.- KW - Index Medicus KW - SOS Response (Genetics) KW - DNA Primers -- genetics KW - Operon KW - Amino Acid Sequence KW - Cloning, Molecular KW - Gene Amplification KW - Mutagenesis KW - Base Sequence KW - Methyl Methanesulfonate -- toxicity KW - Serine Endopeptidases -- genetics KW - DNA, Bacterial -- genetics KW - R Factors -- genetics KW - Molecular Sequence Data KW - Sequence Homology, Amino Acid KW - Genes, Bacterial KW - Bacterial Proteins -- genetics KW - Plasmids -- genetics KW - Escherichia coli -- drug effects KW - Escherichia coli -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72461933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mutation+research&rft.atitle=Identification+of+mucAB-like+homologs+on+two+IncT+plasmids%2C+R394+and+Rts-1.&rft.au=Koch%2C+W+H%3BFern%C3%A1ndez+de+Henestrosa%2C+A+R%3BWoodgate%2C+R&rft.aulast=Koch&rft.aufirst=W&rft.date=2000-12-20&rft.volume=457&rft.issue=1-2&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Mutation+research&rft.issn=00275107&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-08 N1 - Date created - 2001-02-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Collaborative Education To Ensure Patient Safety. AN - 62190919; ED468611 AB - Results of a joint meeting between national advisory councils in medicine and nursing on physician-nurse collaboration to enhance patient safety are reported. Recommendations on which participants reached consensus are organized by these Institute of Medicine (IOM) themes: establish a national focus to create leadership through research and protocols to enhance the knowledge base about safety; identify and learn from errors through immediate, strong mandatory reporting efforts; raise standards and expectations for improvements in safety; and create safety systems inside health care organizations through implementation of safe practices at the delivery level. A summary of collaborative activities follows. The issues as outlined by speakers at the meeting are organized by IOM themes. Seven manuscripts are "Putting Patients First: Improving Patient Safety Through Collaborative Education" (Wakefield); "Managing Error for System Improvement" (Kaplan, Battles); "Preventing Patient Injuries" (James); "Collaborative Education to Improve Public Safety" (Conway-Welch); "Learning to Improve Complex Systems of Care" (Headrick); "Using Clinical Computing to Enhance Physician and Nurse Collaboration and to Improve Patient Safety" (Gardner); and "Collaborative Education to Improve Public Safety" (Swankin). Three annotated bibliographies are appended: nurse-physician collaboration in practice (71 items); interdisciplinary (interprofessional) education (88); and medical errors and error prevention (79). (YLB) Y1 - 2000/12/20/ PY - 2000 DA - 2000 Dec 20 SP - 151 PB - Health Resources and Services Administration Information Center, P.O. Box 2910, Merrifield, VA 22116. Tel: 1-888-Ask-HRSA; Fax: 703-821-2098; e-mail: ask@hrsa.gov; Web site: http://www.ask.hrsa.gov. For full text: http://www.bhpr.hrsa.gov/dn/nacnep. KW - Institute of Medicine DC KW - Nurse Physician Relationship KW - Patient Care KW - ERIC, Resources in Education (RIE) KW - Postsecondary Education KW - Interprofessional Relationship KW - Coordination KW - Cooperative Programs KW - Safety KW - Nurses KW - Patients KW - Health Education KW - Professional Continuing Education KW - Error Correction KW - Medical Education KW - Health Promotion KW - Advisory Committees KW - Educational Cooperation KW - Partnerships in Education KW - Physicians KW - Error Patterns KW - Interdisciplinary Approach KW - Malpractice KW - Annotated Bibliographies KW - Medical Services KW - Education Work Relationship UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62190919?accountid=14244 LA - English DB - ERIC N1 - Availability - Level 1 - Available online, if indexed January 1993 onward N1 - SuppNotes - Report to the Secretary of the U.S. Department of N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - Quantification of Etheno-DNA Adducts Using Liquid Chromatography, On-Line Sample Processing, and Electrospray Tandem Mass Spectrometry AN - 17764635; 4821002 AB - Etheno-DNA adducts are promutagenic lesions present in normal animal and human tissues that are believed to be important in the etiology of cancer related to diet and lifestyle. A method has been developed for the quantification of trace levels of etheno-DNA adducts using on-line sample preparation coupled with liquid chromatography and electrospray tandem mass spectrometry. The use of automated solid-phase extraction and stable labeled internal standards permitted the robust determination of ethenodeoxyadenosine contained in crude DNA hydrolysates from untreated rodent and human tissues at levels on the order of one adduct in 10 super(8) normal nucleotides from 100 mu g of DNA. Inherent analyte response and matrix interference made sensitivity for simultaneous determination of ethenodeoxycytidine approximately 5-fold lower. The method was applied to the analysis of liver DNA from untreated and urethane-treated B6C3F1 mice, untreated rat liver, human placenta, and several commercial DNA preparations. Some sources of potential artifactual formation of etheno-DNA adducts were investigated. JF - Chemical Research in Toxicology AU - Doerge AU - Churchwell, MI AU - Fang, Jia-Long AU - Beland, F A AD - Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA Y1 - 2000/12/18/ PY - 2000 DA - 2000 Dec 18 SP - 1259 EP - 1264 VL - 13 IS - 12 SN - 0893-228X, 0893-228X KW - measuring techniques KW - electrospray tandem mass spectrometry KW - on-line sample processing KW - Toxicology Abstracts KW - DNA adducts KW - Liquid chromatography KW - X 24222:Analytical procedures UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17764635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemical+Research+in+Toxicology&rft.atitle=Quantification+of+Etheno-DNA+Adducts+Using+Liquid+Chromatography%2C+On-Line+Sample+Processing%2C+and+Electrospray+Tandem+Mass+Spectrometry&rft.au=Doerge%3BChurchwell%2C+MI%3BFang%2C+Jia-Long%3BBeland%2C+F+A&rft.aulast=Doerge&rft.aufirst=&rft.date=2000-12-18&rft.volume=13&rft.issue=12&rft.spage=1259&rft.isbn=&rft.btitle=&rft.title=Chemical+Research+in+Toxicology&rft.issn=0893228X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - DNA adducts; Liquid chromatography ER - TY - JOUR T1 - Lung responses to hypothyroidism, hyperthyroidism, and lipopolysaccharide challenge in rats. AN - 72515365; 11127416 AB - The objectives of this investigation were to study the effects of hypo- and hyperthyroidism on some factors involved in lung injury under basal conditions (air exposure) and during an inflammatory response induced by inhalation exposure to lipopolysaccharide (LPS; 100 microg/ml; 3 h) in adult rats. Thyroid status was altered by thyroidectomy or thyroxine injections for 15 d. Hyperthyroidism alone caused a greater degree of lung cell damage, an increase in the permeability of the alveolar-capillary barrier, a rise in the total number of phagocytic cells obtained by bronchoalveolar lavage (BAL), and enhanced nitric oxide (NO) release by phagocytic cells relative to that in euthyroid control animals. Hypothyroidism alone was associated with opposite effects. Exposure of animals to LPS produced inflammatory responses, which included significant increases in lung cell damage, permeability of the alveolar-capillary barrier, number of phagocytic cells obtained by BAL, and NO production by the phagocytic cells. In general, hyperthyroidism enhanced the effects of LPS, while hypothyroidism reduced LPS-induced responses. These results suggest that thyroid status alone can affect some of the factors involved in lung injury and also modulate some of the inflammatory effects of LPS. Hyperthyroidism tends to enhance lung injury, while hypothyroidism seems to reduce lung injury. JF - Journal of toxicology and environmental health. Part A AU - Huffman, L J AU - Judy, D J AU - Rao, K M AU - Frazer, D G AU - Goldsmith, W T AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA. ljh3@cdc.gov Y1 - 2000/12/15/ PY - 2000 DA - 2000 Dec 15 SP - 623 EP - 639 VL - 61 IS - 7 SN - 1528-7394, 1528-7394 KW - Albumins KW - 0 KW - Endotoxins KW - Lipopolysaccharides KW - Nitric Oxide KW - 31C4KY9ESH KW - endotoxin, Escherichia coli KW - 67924-63-4 KW - L-Lactate Dehydrogenase KW - EC 1.1.1.27 KW - Thyroxine KW - Q51BO43MG4 KW - Index Medicus KW - Albumins -- metabolism KW - Animals KW - Cell Count KW - Nitric Oxide -- metabolism KW - Endotoxins -- pharmacology KW - Rats KW - Rats, Sprague-Dawley KW - Capillaries -- pathology KW - Cell Membrane Permeability -- drug effects KW - Thyroxine -- toxicity KW - Body Weight -- drug effects KW - Phagocytes -- drug effects KW - Bronchoalveolar Lavage Fluid -- cytology KW - L-Lactate Dehydrogenase -- metabolism KW - Male KW - Hyperthyroidism -- pathology KW - Hypothyroidism -- pathology KW - Lipopolysaccharides -- toxicity KW - Lung -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72515365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Lung+responses+to+hypothyroidism%2C+hyperthyroidism%2C+and+lipopolysaccharide+challenge+in+rats.&rft.au=Huffman%2C+L+J%3BJudy%2C+D+J%3BRao%2C+K+M%3BFrazer%2C+D+G%3BGoldsmith%2C+W+T&rft.aulast=Huffman&rft.aufirst=L&rft.date=2000-12-15&rft.volume=61&rft.issue=7&rft.spage=623&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-18 N1 - Date created - 2000-12-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Dermal and systemic toxicity after application of semisynthetic metal-working fluids in B6C3F1 mice. AN - 72510876; 11127413 AB - About 10 million industrial workers of both sexes are exposed to metal-working fluids (MWFs) via inhalation, skin or both. Our preliminary results, following dermal application of 200 microl of 50% unused (neat) semisynthetic MWF (pH 7 or pH 9.7) to the unshaved backs of 6-wk-old B6C3F1 mice, twice a week for 6 wk, produced significant increase in weights of the liver of both sexes. The purpose of the present study was to determine if this weight change was related to oxidative stress subsequent to MWF exposure and also to determine whether ethanol intake influences this effect. Therefore, 6-mo-old mice of both sexes were exposed to MWFs following the protocol just described, except that the topical application was with 5% MWFs (pH 7 and 9.7, 5 d/wk) with or without adding 5% ethanol to their drinking water (7 d/wk) for 13 wk. The skin histamine levels and mast-cell numbers were significantly increased in the female group treated with 55% MWF (pH 7). The ascorbic acid levels in the liver (both sexes) (all groups except 5%, MWF pH 9.7 males) and testes were reduced significantly. Malondialdehyde levels in the male liver were significantly increased with topical MWF exposure. Glutathione levels were reduced significantly in both male and female liver after 5% MWF (pH 7). Alcohol dehydrogenase activity of the male liver increased significantly after MWF (pH 7). These results suggest that MWFs are absorbed through the skin and produce toxicity in the liver of both sexes and in the male gonads. This may represent an important health risk to MWF-exposed industrial workers, and ethanol may exacerbate this risk. JF - Journal of toxicology and environmental health. Part A AU - Al-Humadi, N H AU - Shvedova, A A AU - Batteli, L AU - Diotte, N AU - Castranova, V AU - Kommineni, C AD - Health Effects Laboratory Division, NIOSH, CDC, Morgantown, West Virginia 26505, USA. Y1 - 2000/12/15/ PY - 2000 DA - 2000 Dec 15 SP - 579 EP - 589 VL - 61 IS - 7 SN - 1528-7394, 1528-7394 KW - Indicators and Reagents KW - 0 KW - Malondialdehyde KW - 4Y8F71G49Q KW - Histamine KW - 820484N8I3 KW - Alcohol Dehydrogenase KW - EC 1.1.1.1 KW - Glutathione KW - GAN16C9B8O KW - Ascorbic Acid KW - PQ6CK8PD0R KW - Index Medicus KW - Malondialdehyde -- metabolism KW - Animals KW - Mast Cells -- metabolism KW - Glutathione -- metabolism KW - Mice KW - Histamine -- metabolism KW - Alcohol Dehydrogenase -- metabolism KW - Ascorbic Acid -- metabolism KW - Mast Cells -- drug effects KW - Male KW - Female KW - Industrial Oils -- toxicity KW - Skin Diseases -- metabolism KW - Skin Diseases -- pathology KW - Skin Diseases -- chemically induced KW - Metallurgy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72510876?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Dermal+and+systemic+toxicity+after+application+of+semisynthetic+metal-working+fluids+in+B6C3F1+mice.&rft.au=Al-Humadi%2C+N+H%3BShvedova%2C+A+A%3BBatteli%2C+L%3BDiotte%2C+N%3BCastranova%2C+V%3BKommineni%2C+C&rft.aulast=&rft.aufirst=&rft.date=2000-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=0160502608&rft.btitle=Healthy+People+2010%3A+Understanding+and+Improving+Health.&rft.title=Healthy+People+2010%3A+Understanding+and+Improving+Health.&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-18 N1 - Date created - 2000-12-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of ochratoxin A on cytotoxicity and cell differentiation in cultured rat embryonic cells. AN - 72506825; 11127415 AB - In the present study, the effects of ochratoxin A (OTA) on cytotoxicity, cell differentiation, and other cell functions in the embryonic midbrain cells, which are dopaminergic, were compared to those in the limb bud cells, which are nondopaminergic, to assess the selectivity of OTA central action. Twelve-day rat embryo midbrain and limb bud cells were cultured in Dulbecco's modified Eagle's medium nutrient and Ham's F12 (1:1) mix ture containing 10% Nuserum for 96 h in the presence of various concentrations of OTA. OTA signicfiantly reduced the levels of protein, DNA and glutathione, and [H]thymidine incorporation into DNA in both embryonic midbrain and limb bud cells in a similar concentration-dependent manner. The IC50 values for cytotoxicity measured by neutral red uptake were 1.10 microM in the midbrain cells and 1.05 microM in the limb bud cells. The IC50 values of cell differentiation were 1.10 microM in the midbrain cells and 1.0 microM in the limb bud cells. The addition of exogenous glutathione (32.5 microM) did not change the OTA-induced fall in protein and DNA levels, or the IC50 values of cytotoxicity and differentiation in the midbrain and limb bud cells. Data show that OTA does not appear to exert a selective toxic dopaminergic cell action and that OTA-induced cytotoxicity and inhibition of cell differentiation were not prevented by exogenous glutathione. JF - Journal of toxicology and environmental health. Part A AU - Hong, J T AU - Park, K L AU - Han, S Y AU - Park, K S AU - Kim, H S AU - Oh, S D AU - Lee, R D AU - Jang, S J AD - National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul. jinthong@kfda.go.kr Y1 - 2000/12/15/ PY - 2000 DA - 2000 Dec 15 SP - 609 EP - 621 VL - 61 IS - 7 SN - 1528-7394, 1528-7394 KW - Carcinogens KW - 0 KW - Ochratoxins KW - Proteins KW - ochratoxin A KW - 1779SX6LUY KW - DNA KW - 9007-49-2 KW - Glutathione KW - GAN16C9B8O KW - Thymidine KW - VC2W18DGKR KW - Index Medicus KW - Limb Buds -- drug effects KW - Animals KW - Limb Buds -- cytology KW - DNA -- metabolism KW - Glutathione -- metabolism KW - Cell Division -- drug effects KW - Limb Buds -- embryology KW - Mesencephalon -- cytology KW - Proteins -- metabolism KW - Thymidine -- metabolism KW - Rats KW - Mesencephalon -- drug effects KW - Rats, Sprague-Dawley KW - Cell Survival -- drug effects KW - Cells, Cultured KW - Mesencephalon -- embryology KW - Cell Differentiation -- drug effects KW - Ochratoxins -- toxicity KW - Embryo, Mammalian -- cytology KW - Carcinogens -- toxicity KW - Embryo, Mammalian -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72506825?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Effects+of+ochratoxin+A+on+cytotoxicity+and+cell+differentiation+in+cultured+rat+embryonic+cells.&rft.au=Hong%2C+J+T%3BPark%2C+K+L%3BHan%2C+S+Y%3BPark%2C+K+S%3BKim%2C+H+S%3BOh%2C+S+D%3BLee%2C+R+D%3BJang%2C+S+J&rft.aulast=Hong&rft.aufirst=J&rft.date=2000-12-15&rft.volume=61&rft.issue=7&rft.spage=609&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-18 N1 - Date created - 2000-12-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistein AN - 17750732; 4813890 AB - Fecal bacteria from a healthy individual were screened for the specific bacteria involved in the metabolism of dietary isoflavonoids. Two strains of bacteria capable of producing primary and secondary metabolites from the natural isoflavone glycosides daidzin and genistin were detected. The metabolites were identified by comparison of their HPLC/mass, super(1)H NMR and UV spectra with those of standard and synthetic compounds. Both Escherichia coli HGH21 and the gram-positive strain HGH6 converted daidzin and genistin to the their respective aglycones daidzein and genistein. Under anoxic conditions, strain HGH6 further metabolized the isoflavones daidzein and genistein to dihydrodaidzein and dihydrogenistein, respectively. The reduction of a double bond between C-2 and C-3 to a single bond was isoflavonoid-specific by strain HGH6, which did not reduce a similar bond in the flavonoids apigenin and chrysin. Strain HGH6 did not further metabolize dihydrodaidzein and dihydrogenistein. This is the first study in which specific colonic bacteria that are involved in the metabolism of daidzin and genistin have been detected. JF - Archives of Microbiology AU - Hur, H G AU - Lay, JOJr AU - Beger, R D AU - Freeman, J P AU - Rafii, F AD - Division of Microbiology, National Center for Toxicological Research, U.S. FDA, Jefferson, AR, 72079-9502, USA, frafii@nctr.fda.gov Y1 - 2000/12/11/ PY - 2000 DA - 2000 Dec 11 SP - 422 EP - 428 PB - Springer-Verlag VL - 174 IS - 6 SN - 0302-8933, 0302-8933 KW - man KW - daidzien KW - isoflavonoids KW - Microbiology Abstracts B: Bacteriology KW - Microflora KW - Intestine KW - Escherichia coli KW - Genistein KW - J 02841:Microflora UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17750732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Microbiology&rft.atitle=Isolation+of+human+intestinal+bacteria+metabolizing+the+natural+isoflavone+glycosides+daidzin+and+genistein&rft.au=Hur%2C+H+G%3BLay%2C+JOJr%3BBeger%2C+R+D%3BFreeman%2C+J+P%3BRafii%2C+F&rft.aulast=Hur&rft.aufirst=H&rft.date=2000-12-11&rft.volume=174&rft.issue=6&rft.spage=422&rft.isbn=&rft.btitle=&rft.title=Archives+of+Microbiology&rft.issn=03028933&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Escherichia coli; Intestine; Microflora; Genistein ER - TY - JOUR T1 - Neuronal degeneration in the limbic system of weanling rats exposed to saline, hyperthermia or d-amphetamine. AN - 72455785; 11102570 AB - Neuronal degeneration was detected in the tenia tecta and other regions of the anterior limbic system of male weanling rats 3 days after four doses of 5 mg/kg d-amphetamine (4 x 5 mg/kg AMPH) when seizures occurred during AMPH exposure. Neurodegeneration in the parietal cortex, loss of tyrosine hydroxylase immunoreactivity in the caudate-putamen (CPu) and decreases in CPu tissue dopamine levels in weanlings was much less than those previously observed in adults. The neurotoxicity seen in the parietal cortex and CPu of the weanlings was much less than previously seen in adults even though severe hyperthermia and the behavior of retrograde propulsion occurred during AMPH exposure. Neurodegeneration was not detected in any of the previously mentioned brain regions in controls and weanlings made hyperthermic by a warm environment. However, signs of spontaneous neurodegeneration were seen in the posterior piriform cortex (Pir), posteriolateral cortical amygdaloid nucleus (PLCo), and the amygdalopiriform transition area (APir) of control weanlings. The doses of AMPH and the degree of hyperthermia necessary to induce seizures were substantially lower in weanlings compared to those previously observed in adult rats. Further studies will be necessary to determine if the susceptibility of weanlings to AMPH-induced seizures is related to or dependent on the same processes involved in producing degeneration in the posterior limbic system of saline controls. JF - Brain research AU - Bowyer, J F AD - Division of Neurotoxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA. Y1 - 2000/12/08/ PY - 2000 DA - 2000 Dec 08 SP - 166 EP - 171 VL - 885 IS - 2 SN - 0006-8993, 0006-8993 KW - Central Nervous System Stimulants KW - 0 KW - Glial Fibrillary Acidic Protein KW - Sodium Chloride KW - 451W47IQ8X KW - Dextroamphetamine KW - TZ47U051FI KW - Index Medicus KW - Animals KW - Caudate Nucleus -- metabolism KW - Prosencephalon -- metabolism KW - Glial Fibrillary Acidic Protein -- metabolism KW - Weaning KW - Caudate Nucleus -- drug effects KW - Motor Activity -- physiology KW - Rats KW - Rats, Sprague-Dawley KW - Glial Fibrillary Acidic Protein -- drug effects KW - Prosencephalon -- drug effects KW - Putamen -- physiology KW - Motor Activity -- drug effects KW - Male KW - Putamen -- drug effects KW - Seizures -- chemically induced KW - Fever -- chemically induced KW - Limbic System -- drug effects KW - Limbic System -- metabolism KW - Nerve Degeneration -- metabolism KW - Nerve Degeneration -- chemically induced KW - Central Nervous System Stimulants -- adverse effects KW - Fever -- metabolism KW - Sodium Chloride -- pharmacology KW - Dextroamphetamine -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72455785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+Pathology&rft.atitle=Virtual+Neuropathology%3A+Three-Dimensional+Visualization+of+Lesions+Due+to+Toxic+Insult&rft.au=Lester%2C+David+S%3BPine%2C+PScott%3BDelnomdedieu%2C+Marielle%3BJohannessen%2C+Jan+N%3BJohnson%2C+GAllan&rft.aulast=Lester&rft.aufirst=David&rft.date=2000-01-01&rft.volume=28&rft.issue=1&rft.spage=100&rft.isbn=&rft.btitle=&rft.title=Toxicologic+Pathology&rft.issn=01926233&rft_id=info:doi/10.1177%2F019262330002800112 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-03-01 N1 - Date created - 2001-02-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A Prospective Study of Back Belts for Prevention of Back Pain and Injury AN - 18244743; 5304249 AB - Despite scientific uncertainties about effectiveness, wearing back belts in the hopes of preventing costly and disabling low back injury in employees is becoming common in the workplace. To evaluate the effectiveness of using back belts in reducing back injury claims and low back pain. Prospective cohort study. From April 1996 through April 1998, we identified material-handling employees in 160 new retail merchandise stores (89 required back belt use; 71 had voluntary back belt use) in 30 states (from New Hampshire to Michigan in the north and from Florida to Texas in the south); data collection ended December 1998, median follow-up was 6 1/2 months. A referred sample of 13,873 material handling employees provided 9377 baseline interviews and 6311 (67%) follow-up interviews; 206 (1.4%) refused baseline interview. Incidence rate of material-handling back injury workers' compensation claims and 6-month incidence rate of self-reported low back pain. Neither frequent back belt use nor a belt-requirement store policy was significantly associated with back injury claim rates or self-reported back pain. Rate ratios comparing back injury claims of those who reported wearing back belts usually every day and once or twice a week vs those who reported wearing belts never or once or twice a month were 1.22 (95% confidence interval [CI], 0.87-1.70) and 0.95 (95% CI, 0.56-1.59), respectively. The respective odds ratios for low back pain incidence were 0.97 (95% CI, 0.83-1.13) and 0.92 (95% CI, 0.73-1.16). In the largest prospective cohort study of back belt use, adjusted for multiple individual risk factors, neither frequent back belt use nor a store policy that required belt use was associated with reduced incidence of back injury claims or low back pain. JF - Journal of the American Medical Association AU - Wassell, J T AU - Gardner, LI AU - Landsittel, D P AU - Johnston, J J AU - Johnston, J M AD - Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Safety Research, 1095 Willowdale Rd, Morgantown, WV 26505, USA, jtw2@cdc.gov Y1 - 2000/12/06/ PY - 2000 DA - 2000 Dec 06 SP - 2727 EP - 2732 VL - 284 IS - 21 SN - 0098-7484, 0098-7484 KW - back belts KW - back pain KW - working conditions KW - Health & Safety Science Abstracts KW - Injuries KW - Materials handling KW - Occupational safety KW - Protective equipment KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18244743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Medical+Association&rft.atitle=A+Prospective+Study+of+Back+Belts+for+Prevention+of+Back+Pain+and+Injury&rft.au=Wassell%2C+J+T%3BGardner%2C+LI%3BLandsittel%2C+D+P%3BJohnston%2C+J+J%3BJohnston%2C+J+M&rft.aulast=Wassell&rft.aufirst=J&rft.date=2000-12-06&rft.volume=284&rft.issue=21&rft.spage=2727&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Medical+Association&rft.issn=00987484&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Occupational safety; Protective equipment; Materials handling; Injuries ER - TY - JOUR T1 - Analytical procedure for quantifying five compounds suspected as possible contaminants in recycled paper/paperboard for food packaging. AN - 72602399; 11141258 AB - Because contaminants in recycled paper intended for food packaging could be a risk to public health, analytical methods are needed to identify and quantify residues of concern in paper/paperboard. The U. S. Food and Drug Administration is considering development of a guidance document for testing levels of contaminants that might be retained through paper recycling processes. An analytical procedure was developed using paper spiked with suspected contaminants at concentrations of 1-50 ppm in the paper. Benzophenone, dimethyl phthalate, anthracene, methyl stearate, and pentachlorophenol were introduced by soaking the paper in a solution in acetone at 25 degrees C for 24 h; the paper was removed and dried by evaporating the solvent with nitrogen. The model contaminant residues were extracted from the paper using ultrasonication and quantified by GC with flame ionization and electron capture detectors. Recoveries from the spiked paper were 80-109% with a repeatability of +/-4%. The method was also used to analyze commercial recycled paperboard to validate its applicability. JF - Journal of agricultural and food chemistry AU - Song, Y S AU - Park, H J AU - Komolprasert, V AD - Division of Food Processing and Packaging, U.S. Food and Drug Administration, National Center for Food Safety and Technology, 6502 South Archer Road, Summit-Argo, Illinois 60501, and Rural Living Science Institute, 88-2 Seodundong, Suwon, Kor. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 5856 EP - 5859 VL - 48 IS - 12 SN - 0021-8561, 0021-8561 KW - Index Medicus KW - Reproducibility of Results KW - Chromatography, Gas KW - Ultrasonics KW - Paper KW - Food Contamination -- analysis KW - Food Packaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72602399?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Analytical+procedure+for+quantifying+five+compounds+suspected+as+possible+contaminants+in+recycled+paper%2Fpaperboard+for+food+packaging.&rft.au=Song%2C+Y+S%3BPark%2C+H+J%3BKomolprasert%2C+V&rft.aulast=Song&rft.aufirst=Y&rft.date=2000-12-01&rft.volume=48&rft.issue=12&rft.spage=5856&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-10-25 N1 - Date created - 2001-05-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Determination of organochlorine and organophosphorus pesticide residues in eggs using a solid phase extraction cleanup. AN - 72594478; 11141294 AB - A multiresidue solid phase extraction (SPE) method for the isolation and subsequent gas chromatographic determination of nonpolar organochlorine and polar organophosphorus pesticide residues in eggs is described. The method uses an acetonitrile extraction followed by an SPE cleanup using graphitized carbon black and aminopropyl SPE columns. Organophosphorus pesticides are determined by gas chromatography with flame photometric detection. After further cleanup of the extract using Florisil SPE columns, organochlorine pesticides are determined by gas chromatography with electron capture detection. Studies were performed using eggs containing both fortified and incurred pesticide residues. The average recoveries were 86-108% for 8 fortified organochlorine pesticide residues and 61-149% for 28 fortified organophosphorus pesticide residues. JF - Journal of agricultural and food chemistry AU - Schenck, F J AU - Donoghue, D J AD - Center for Veterinary Medicine, U.S. Food and Drug Administration, 8401 Muirkirk Road, Laurel, Maryland 20708, USA. fschenck@ora.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 6412 EP - 6415 VL - 48 IS - 12 SN - 0021-8561, 0021-8561 KW - Insecticides KW - 0 KW - Organophosphorus Compounds KW - Pesticide Residues KW - Index Medicus KW - Animals KW - Chickens KW - Female KW - Chromatography, Gas -- methods KW - Organophosphorus Compounds -- analysis KW - Pesticide Residues -- isolation & purification KW - Eggs -- analysis KW - Pesticide Residues -- analysis KW - Insecticides -- isolation & purification KW - Insecticides -- analysis KW - Organophosphorus Compounds -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72594478?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Determination+of+organochlorine+and+organophosphorus+pesticide+residues+in+eggs+using+a+solid+phase+extraction+cleanup.&rft.au=Schenck%2C+F+J%3BDonoghue%2C+D+J&rft.aulast=Schenck&rft.aufirst=F&rft.date=2000-12-01&rft.volume=48&rft.issue=12&rft.spage=6412&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-10-25 N1 - Date created - 2001-05-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Biotransformation of vinclozolin by the fungus Cunninghamella elegans. AN - 72593997; 11312787 AB - This study investigated the biotransformation of the dicarboximide fungicide vinclozolin [3-(3,5-dichlorophenyl)-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione] by the fungus Cunninghamella elegans. Experiments with phenyl-[U-ring-14C]vinclozolin showed that after 96 h incubation, 93% had been transformed to four major metabolites. Metabolites were separated by HPLC and characterized by mass and NMR spectroscopy. Biotransformation occurred predominantly on the oxazolidine-2,4-dione portion of vinclozolin. The metabolites were identified as the 3R- and 3S- isomers of 3',5'-dichloro-2,3,4-trihydroxy-2-methylbutyranilide, N-(2-hydroxy-2-methyl-1-oxobuten-3-yl)-3,5-dichlorophenyl-1-carbamic acid, and 3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide. The enanilide compound has been reported previously as a plant and mammalian metabolite and is implicated to contain antiandrogenic activity. The 3R- and 3S- isomers of 3',5'-dichloro-2,3,4-trihydroxy-2-methylbutyranilide are novel metabolites. JF - Journal of agricultural and food chemistry AU - Pothuluri, J V AU - Freeman, J P AU - Heinze, T M AU - Beger, R D AU - Cerniglia, C E AD - National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA. JPothuluri@nctr.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 6138 EP - 6148 VL - 48 IS - 12 SN - 0021-8561, 0021-8561 KW - Fungicides, Industrial KW - 0 KW - Oxazoles KW - vinclozolin KW - JJ258EZN1I KW - Index Medicus KW - Biotransformation KW - Isomerism KW - Fungicides, Industrial -- pharmacokinetics KW - Oxazoles -- pharmacokinetics KW - Cunninghamella -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72593997?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Biotransformation+of+vinclozolin+by+the+fungus+Cunninghamella+elegans.&rft.au=Pothuluri%2C+J+V%3BFreeman%2C+J+P%3BHeinze%2C+T+M%3BBeger%2C+R+D%3BCerniglia%2C+C+E&rft.aulast=Pothuluri&rft.aufirst=J&rft.date=2000-12-01&rft.volume=48&rft.issue=12&rft.spage=6138&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-10-25 N1 - Date created - 2001-04-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Determination of total 14C residues of sarafloxacin in eggs of laying hens. AN - 72590367; 11141293 AB - [14C]sarafloxacin was orally administered to six laying hens for five consecutive days. Eggs were collected for 15 days after the initial drug treatment. Egg yolk and egg albumen were separated and assayed for total radioactive residues (TRR) using a combustion oxidizer and scintillation counting techniques. Radioactivity was detected in egg yolk and egg albumen on the second day of dosing and reached a maximum at 24 h after drug withdrawal. Thereafter, the sarafloxacin TRR levels in egg albumen declined rapidly and were undetectable 2 days after the last dose, whereas the levels in egg yolk declined at a much slower rate and were undetectable 7 days after drug withdrawal. In both the egg albumen and yolk, HPLC analysis indicated that the parent sarafloxacin was the major component. JF - Journal of agricultural and food chemistry AU - Chu, P S AU - Donoghue, D J AU - Shaikh, B AD - Center for Veterinary Medicine, U.S. Food and Drug Administration, 8401 Muirkirk Road, Laurel, Maryland 20708, USA. pchu@cmv.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 6409 EP - 6411 VL - 48 IS - 12 SN - 0021-8561, 0021-8561 KW - Anti-Infective Agents KW - 0 KW - Carbon Isotopes KW - Egg Proteins KW - Fluoroquinolones KW - Ciprofloxacin KW - 5E8K9I0O4U KW - sarafloxacin KW - RC3WJ907XY KW - Index Medicus KW - Administration, Oral KW - Animals KW - Drug Residues -- metabolism KW - Female KW - Chromatography, High Pressure Liquid KW - Egg Proteins -- analysis KW - Ciprofloxacin -- administration & dosage KW - Anti-Infective Agents -- pharmacokinetics KW - Ciprofloxacin -- pharmacokinetics KW - Egg Yolk -- chemistry KW - Anti-Infective Agents -- administration & dosage KW - Ciprofloxacin -- analogs & derivatives KW - Chickens -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72590367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Determination+of+total+14C+residues+of+sarafloxacin+in+eggs+of+laying+hens.&rft.au=Chu%2C+P+S%3BDonoghue%2C+D+J%3BShaikh%2C+B&rft.aulast=Chu&rft.aufirst=P&rft.date=2000-12-01&rft.volume=48&rft.issue=12&rft.spage=6409&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-10-25 N1 - Date created - 2001-05-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Imaging residue transfer into egg yolks. AN - 72589469; 11141297 AB - Prediction models for residue transfer into eggs are being developed. Recent results indicate that the developing egg yolk serves as an important storage depot for chemical residues. The current study was conducted to visualize incorporation and potential compartmentalization of drug residues in developing egg yolks. To this end, the drug magnevist was injected into hens to evaluate drug transfer into either early- or late-developing yolks. High-resolution magnetic resonance images (MRI) of drug residues in eggs were acquired using a 1.5 T Siemens Magnetom clinical scanner. A 10-cm circular surface coil was used for receiving the magnetic resonance signal. The eggs were positioned inside the coil cavity for an improved signal to noise ratio (SNR). Gradient-echo images were used to locate the centers of the eggs and to prescribe the position of the high-resolution image slab. The images were recorded using an inversion time (T1) weighted magnetization-prepared, rapid acquisition, gradient-recalled-echo (MPRAGE) pulse sequence. The sequence parameters used were as follows: repetition time (TR) equals 12 ms, echo time (TE) equals 5 ms, field of view (FOV) equals 200, TI = 10 ms, 1.25-mm slice thickness, and a matrix of 200 x 256. Following dosing, images of drug residues in eggs indicate that drugs can be incorporated and compartmentalized into ring structures within individual developing egg yolks. These results have significant human food safety implications because even after only a single dose, sequestered drug residues may be stored and later released to contaminate eggs for days to weeks after dosing. JF - Journal of agricultural and food chemistry AU - Donoghue, D J AU - Myers, K AD - Division of Animal Research, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, Maryland 20708, USA. ddonoghue@comp.uark.edu Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 6428 EP - 6430 VL - 48 IS - 12 SN - 0021-8561, 0021-8561 KW - Index Medicus KW - Magnetic Resonance Imaging KW - Animals KW - Chickens KW - Safety KW - Food Contamination -- analysis KW - Time Factors KW - Models, Biological KW - Female KW - Drug Residues -- analysis KW - Egg Yolk -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72589469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Imaging+residue+transfer+into+egg+yolks.&rft.au=Donoghue%2C+D+J%3BMyers%2C+K&rft.aulast=Donoghue&rft.aufirst=D&rft.date=2000-12-01&rft.volume=48&rft.issue=12&rft.spage=6428&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-10-25 N1 - Date created - 2001-05-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Distribution of total 14C residue in egg yolk, albumen, and tissues following oral [14C]sulfamethazine administration to hens. AN - 72587438; 11141292 AB - The distribution of total 14C residues was studied in egg yolk and albumen after administration of either single or multiple oral dosages of [14C]sulfamethazine (SMZ). One day after a single dose of [14C]SMZ (121 mg of sulfamethazine, 2.42 x 10(7) dpm), the 14C residue concentration peaked in egg albumen and egg yolk with the concentration in the former >4-fold greater than in the latter. Three days postdose, the 14C residue concentration in the yolk was approximately 7-fold higher than in the egg albumen. A multiple dose of [14C]SMZ containing sulfamethazine mass equivalent of an average therapeutic dose (282 mg, 2.9 x 10(7) dpm) for chickens was also administered orally for six consecutive days to hens. A significantly reduced level of egg production was observed during the medication, and most of the hens stopped laying eggs after the last dose. The 14C residue concentrations peaked on the last day (sixth) of medication in egg albumen and yolk. The 14C residue concentrations were also measured in liver, muscle, blood, and plasma of chickens sacrificed at 1, 24, 48, and 72 h after the last dose. Highest concentrations of 14C residue were accumulated in liver followed by, in decreasing order, blood, plasma, and muscle. JF - Journal of agricultural and food chemistry AU - Shaikh, B AU - Chu, P S AD - Center for Veterinary Medicine, U.S. Food and Drug Administration, 8401 Muirkirk Road, Laurel, Maryland 20708, USA. bshaikh@cmv.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 6404 EP - 6408 VL - 48 IS - 12 SN - 0021-8561, 0021-8561 KW - Carbon Isotopes KW - 0 KW - Egg Proteins KW - Sulfamethazine KW - 48U51W007F KW - Index Medicus KW - Administration, Oral KW - Animals KW - Body Burden KW - Food Contamination KW - Drug Residues KW - Time Factors KW - Female KW - Egg Proteins -- analysis KW - Chickens -- physiology KW - Sulfamethazine -- administration & dosage KW - Egg Yolk -- chemistry KW - Chickens -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72587438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+agricultural+and+food+chemistry&rft.atitle=Distribution+of+total+14C+residue+in+egg+yolk%2C+albumen%2C+and+tissues+following+oral+%5B14C%5Dsulfamethazine+administration+to+hens.&rft.au=Shaikh%2C+B%3BChu%2C+P+S&rft.aulast=Shaikh&rft.aufirst=B&rft.date=2000-12-01&rft.volume=48&rft.issue=12&rft.spage=6404&rft.isbn=&rft.btitle=&rft.title=Journal+of+agricultural+and+food+chemistry&rft.issn=00218561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-10-25 N1 - Date created - 2001-05-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Neurodevelopmental effects: making the case for biologic plausibility. AN - 72582494; 11233767 AB - It has been suggested that the most critical missing link between science and policy is causality; that is, the establishment of a definite cause-effect relationship between exposure and adverse health effects. As has been clearly demonstrated by the decades-long tobacco debate, causality is extremely difficult to establish with absolute certainty, particularly in the minds of scientists. Because of this, it has been suggested that a "weight of evidence" approach based on biologic plausibility should be used as a surrogate for causality when translating science into policy and public health practice. In the case of neurodevelopmental effects, the case for biologic plausibility is supported by scientific findings from three broad areas consisting of wildlife biology, toxicology, and epidemiology. A striking example of this is provided by research findings from the Great Lakes Basin, an area which has been the focus of significant scientific research for the last thirty years in these three broad areas. In this paper, we examine relevant findings from the Great Lakes Basin and elsewhere as they relate to establishing and supporting the biologic plausibility of neurodevelopmental effects associated with environmental exposures to persistent toxic substances. JF - Neurotoxicology AU - De Rosa, C T AU - Hicks, H E AU - Cibulas, W AU - Jones, D E AD - U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30333, USA. cydo@cdc.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 979 EP - 987 VL - 21 IS - 6 SN - 0161-813X, 0161-813X KW - Environmental Pollutants KW - 0 KW - Index Medicus KW - Animals KW - Great Lakes Region -- epidemiology KW - Humans KW - United States -- epidemiology KW - Environmental Illness -- epidemiology KW - Environmental Pollutants -- toxicity KW - Nervous System -- drug effects KW - Environmental Illness -- chemically induced KW - Nervous System -- growth & development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72582494?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Neurodevelopmental+effects%3A+making+the+case+for+biologic+plausibility.&rft.au=De+Rosa%2C+C+T%3BHicks%2C+H+E%3BCibulas%2C+W%3BJones%2C+D+E&rft.aulast=De+Rosa&rft.aufirst=C&rft.date=2000-12-01&rft.volume=21&rft.issue=6&rft.spage=979&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-05-24 N1 - Date created - 2001-03-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of single injection of methylazoxymethanol at postnatal day one on cell proliferation in different brain regions of male rats. AN - 72575977; 11233761 AB - Methylazoxymethanol (MAM), an aglycone of cycasin extracted from Cycad seed, is reported to induce microencephaly in rats after prenatal or postnatal administration. Forty postnatal day (PND) 1 rats derived from 8 timed-pregnant rats were used to evaluate the effect of a single subcutaneous injection of MAM on PND 1 on cell proliferation in rat brain. All dams were fed NIH-31 diet. In the MAM-treated group, each pup received a single injection of MAM at 10 mg/kg body weight. In the control group, pups were injected with saline solution. Body weight of pups was recorded on PNDs 1, 7, 14, 21, 28, and 60. One male pup in each litter was removed for sacrifice by decapitation on PNDs 7, 14, 21, 28, and 60. The brain was removed and dissected to obtain the brain stem, caudate nucleus, cerebellum, frontal cortex, hippocampus, hypothalamus, and olfactory bulb. The percentage (%) of S-phase cells in the cell cycle for each region was measured as index of cell proliferation. A significant (p<0. 05) reduction in body weight was detected on PND 7. The % S-phase cells in cerebellum on PND 7 and olfactory bulb on PND 14 initially increased and then later decreased. There were significant decreases in the % S-phase cells in both cerebellum and caudate nucleus on PND 21 and olfactory bulb on PND 28. No significant changes were found in other brain regions in cell proliferation activity between the control and MAM-treated groups. The % of S-phase cells in cerebellum decreased 65% on PND 60 but lacked statistical significance due to small number of animals used in each group. The results indicated that a single injection of MAM at 10 mg/kg/body weight on PND 1 inhibited cell proliferation in the cerebellum in a manner that could lead to microencephaly. JF - Neurotoxicology AU - Lu, M H AU - Tang, N AU - Ali, S F AD - National Center for Toxicological Research, Jefferson, AR 72079, USA. mlu@nctr.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 1145 EP - 1151 VL - 21 IS - 6 SN - 0161-813X, 0161-813X KW - Carcinogens KW - 0 KW - Methylazoxymethanol Acetate KW - 592-62-1 KW - methylazoxymethanol KW - JGG19N3YDQ KW - Index Medicus KW - Rats KW - Microcephaly -- pathology KW - Aging -- physiology KW - Animals KW - Rats, Sprague-Dawley KW - Microcephaly -- chemically induced KW - Cell Division -- drug effects KW - Flow Cytometry KW - Male KW - Cell Cycle -- drug effects KW - Methylazoxymethanol Acetate -- toxicity KW - Brain -- cytology KW - Brain -- drug effects KW - Carcinogens -- toxicity KW - Methylazoxymethanol Acetate -- analogs & derivatives KW - Brain -- growth & development KW - Animals, Newborn -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72575977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Effects+of+single+injection+of+methylazoxymethanol+at+postnatal+day+one+on+cell+proliferation+in+different+brain+regions+of+male+rats.&rft.au=Lu%2C+M+H%3BTang%2C+N%3BAli%2C+S+F&rft.aulast=Lu&rft.aufirst=M&rft.date=2000-12-01&rft.volume=21&rft.issue=6&rft.spage=1145&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-05-24 N1 - Date created - 2001-03-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Multigenerational exposure to dietary genistein has no severe effects on nursing behavior in rats. AN - 72575125; 11233769 AB - The phytoestrogen and principal isoflavone in soy, genistein, has adverse effects on reproductive physiology in rodents. Since physiology and behavior are both sensitive to perturbations by estrogens, genistein may produce behavioral alterations as well. This paper reports one aspect of a study in which several adult rodent behaviors will be assessed following long term multigenerational dietary exposure to genistein. Since maternal care may affect offspring behaviors in adulthood, it is important to determine the potential for genistein to affect maternal behavior. Here, rats (F0 generation) were fed soy-free diets containing 0, 5, 100, or 500 ppm genistein (approx. 0, 0.4, 8, and 40 mg/kg/day for an adult) beginning on postnatal day (PND) 42. Two generations of offspring (F1 and F2) were continued on these diets and all treatment groups of the F3 generation were returned to 0 ppm at weaning (PND 22). In the first 3 weeks after parturition (for each generation), dams were assessed on 6 occasions for the presence of the arched back posture with at least one pup nursing. Data were analyzed by 3 way repeated measures analysis of variance (ANOVA) with generation, treatment, and postnatal day as factors, and p<0.05 required for significance. There were no significant interactions among treatment, generation, or day, and no overall effects of treatment or generation. As expected, there was a significant overall effect of day, with animals nursing less on later days (p<0.0001). As assessed here, these results suggest that lifelong and multigenerational exposure to dietary genistein has no severe effects on nursing behavior in rodents. JF - Neurotoxicology AU - Flynn, K M AU - Ferguson, S A AU - Delclos, K B AU - Newbold, R R AD - Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. kflynn@nctr.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 997 EP - 1001 VL - 21 IS - 6 SN - 0161-813X, 0161-813X KW - Anticarcinogenic Agents KW - 0 KW - Estrogens, Non-Steroidal KW - Isoflavones KW - Phytoestrogens KW - Plant Preparations KW - Genistein KW - DH2M523P0H KW - Index Medicus KW - Rats KW - Behavior, Animal -- drug effects KW - Animals KW - Rats, Sprague-Dawley KW - Diet KW - Male KW - Female KW - Anticarcinogenic Agents -- toxicity KW - Lactation -- drug effects KW - Estrogens, Non-Steroidal -- toxicity KW - Genistein -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72575125?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Multigenerational+exposure+to+dietary+genistein+has+no+severe+effects+on+nursing+behavior+in+rats.&rft.au=Flynn%2C+K+M%3BFerguson%2C+S+A%3BDelclos%2C+K+B%3BNewbold%2C+R+R&rft.aulast=Flynn&rft.aufirst=K&rft.date=2000-12-01&rft.volume=21&rft.issue=6&rft.spage=997&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-05-24 N1 - Date created - 2001-03-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Reducing environmental risk associated with laboratory decommissioning and property transfer. AN - 72532746; 11121365 AB - The need for more or less space is a common laboratory problem. Solutions may include renovating existing space, leaving or demolishing old space, or acquiring new space or property for building. All of these options carry potential environmental risk. Such risk can be the result of activities related to the laboratory facility or property (e.g., asbestos, underground storage tanks, lead paint), or the research associated with it (e.g., radioactive, microbiological, and chemical contamination). Regardless of the option chosen to solve the space problem, the potential environmental risk must be mitigated and the laboratory space and/or property must be decommissioned or rendered safe prior to any renovation, demolition, or property transfer activities. Not mitigating the environmental risk through a decommissioning process can incur significant financial liability for any costs associated with future decommissioning cleanup activities. Out of necessity, a functioning system, environmental due diligence auditing, has evolved over time to assess environmental risk and reduce associated financial liability. This system involves a 4-phase approach to identify, document, manage, and clean up areas of environmental concern or liability, including contamination. Environmental due diligence auditing includes a) historical site assessment, b) characterization assessment, c) remedial effort and d) final status survey. General practice standards from the American Society for Testing and Materials are available for conducting the first two phases. However, standards have not yet been developed for conducting the third and final phases of the environmental due diligence auditing process. Individuals involved in laboratory decommissioning work in the biomedical research industry consider this a key weakness. JF - Environmental health perspectives AU - Dufault, R AU - Abelquist, E AU - Crooks, S AU - Demers, D AU - DiBerardinis, L AU - Franklin, T AU - Horowitz, M AU - Petullo, C AU - Sturchio, G AD - Division of Facilities Planning, Engineerinf and Safety, United States Food and Drug Administration, Rockville, Maryland 20857, USA. rdufault@oc.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 1015 EP - 1022 VL - 108 Suppl 6 SN - 0091-6765, 0091-6765 KW - Index Medicus KW - Occupational Exposure KW - Humans KW - Workplace KW - Materials Testing KW - Manufactured Materials KW - Liability, Legal KW - Air Pollution, Indoor -- prevention & control KW - Biomedical Technology KW - Risk Assessment KW - Laboratories KW - Facility Design and Construction UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72532746?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Reducing+environmental+risk+associated+with+laboratory+decommissioning+and+property+transfer.&rft.au=Dufault%2C+R%3BAbelquist%2C+E%3BCrooks%2C+S%3BDemers%2C+D%3BDiBerardinis%2C+L%3BFranklin%2C+T%3BHorowitz%2C+M%3BPetullo%2C+C%3BSturchio%2C+G&rft.aulast=Dufault&rft.aufirst=R&rft.date=2000-12-01&rft.volume=108+Suppl+6&rft.issue=&rft.spage=1015&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=00916765&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-09-20 N1 - Date created - 2001-01-26 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Am J Infect Control. 1996 Aug;24(4):313-42 [8870916] Appl Occup Environ Hyg. 1999 Jun;14(6):369-75 [10429731] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Evaluation of verbal communication problems and indoor environmental quality at a government service office. AN - 72516612; 11141598 JF - Applied occupational and environmental hygiene AU - Tubbs, R L AU - Seitz, T A AD - Hazard Evaluation and Technical Assistance Branch, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 869 EP - 878 VL - 15 IS - 12 SN - 1047-322X, 1047-322X KW - Index Medicus KW - Occupational Health KW - Government KW - Ventilation KW - Voice KW - Humans KW - Air Pollution, Indoor KW - Noise KW - Communication KW - Facility Design and Construction UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72516612?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+occupational+and+environmental+hygiene&rft.atitle=Evaluation+of+verbal+communication+problems+and+indoor+environmental+quality+at+a+government+service+office.&rft.au=Tubbs%2C+R+L%3BSeitz%2C+T+A&rft.aulast=Tubbs&rft.aufirst=R&rft.date=2000-12-01&rft.volume=15&rft.issue=12&rft.spage=869&rft.isbn=&rft.btitle=&rft.title=Applied+occupational+and+environmental+hygiene&rft.issn=1047322X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Serum organochlorine levels and breast cancer: a nested case-control study of Norwegian women. AN - 72512552; 11142422 AB - This study investigated the potential association between organochlorine exposure and breast cancer using stored sera collected from 1973 through 1991 from the Janus Serum Bank in Norway. Breast cancer cases were ascertained prospectively from among 25,431 female serum bank donors. A total of 150 controls were matched to cases by birth dates and dates of sample collection. One g of serum per subject was analyzed for a total of 71 organochlorine compounds. For 6 pesticides [B-hexachlorocyclohexane, heptachlor epoxide, oxychlordane, trans-nonachlor, p, p'-1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene, and p, p'-2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane] and 26 individual polychlorinated biphenyl (PCB) congeners there were >90% of samples over the limit of detection. There was no evidence for higher mean serum levels among cases for any of these compounds, nor any trend of increasing risk associated with higher quartiles of exposure. The remaining compounds (including dieldrin) were analyzed with respect to the proportion of cancer cases and controls having detectable levels; no positive associations were noted in these analyses. Our study did not confirm the recent findings of a Danish study of increased concentrations of dieldrin in the serum of breast cancer cases. The evidence to date on the association between serum organochlorines is not entirely consistent, but there is accumulating evidence that serum levels of p, p'-1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and total PCBs are not important predictors for breast cancer in the general population. Studies to date have not been able to evaluate whether exposure to highly estrogenic, short-lived PCB congeners increases breast cancer risk, nor have they fully evaluated the risk associated with organochlorine exposure in susceptible subgroups or at levels above general population exposure, including women with occupational exposure. JF - Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology AU - Ward, E M AU - Schulte, P AU - Grajewski, B AU - Andersen, A AU - Patterson, D G AU - Turner, W AU - Jellum, E AU - Deddens, J A AU - Friedland, J AU - Roeleveld, N AU - Waters, M AU - Butler, M A AU - DiPietro, E AU - Needham, L L AD - Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 1357 EP - 1367 VL - 9 IS - 12 SN - 1055-9965, 1055-9965 KW - Insecticides KW - 0 KW - Receptors, Estrogen KW - Receptors, Progesterone KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - Regression Analysis KW - Age Factors KW - Blood Banks -- statistics & numerical data KW - Humans KW - Receptors, Estrogen -- analysis KW - Receptors, Progesterone -- analysis KW - Prospective Studies KW - Adult KW - Polychlorinated Biphenyls -- blood KW - Case-Control Studies KW - Middle Aged KW - Adolescent KW - Norway KW - Female KW - Adenocarcinoma -- blood KW - Adenocarcinoma -- chemically induced KW - Breast Neoplasms -- chemically induced KW - Breast Neoplasms -- blood KW - Insecticides -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72512552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.atitle=Serum+organochlorine+levels+and+breast+cancer%3A+a+nested+case-control+study+of+Norwegian+women.&rft.au=Ward%2C+E+M%3BSchulte%2C+P%3BGrajewski%2C+B%3BAndersen%2C+A%3BPatterson%2C+D+G%3BTurner%2C+W%3BJellum%2C+E%3BDeddens%2C+J+A%3BFriedland%2C+J%3BRoeleveld%2C+N%3BWaters%2C+M%3BButler%2C+M+A%3BDiPietro%2C+E%3BNeedham%2C+L+L&rft.aulast=Ward&rft.aufirst=E&rft.date=2000-12-01&rft.volume=9&rft.issue=12&rft.spage=1357&rft.isbn=&rft.btitle=&rft.title=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.issn=10559965&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-08 N1 - Date created - 2001-01-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A laboratory comparison of two media for use in the assessment of dermal exposure to pesticides. AN - 72512386; 11141607 AB - In a laboratory study, gauze pads and Empore filters were compared for their ability to assess the dermal exposure of two insecticides (chlorpyrifos and diazinon) and five herbicides (atrazine, alachlor, metolachlor, cyanazine, and 2,4-D ethylhexyl ester). The analytes, when analyzed by gas chromatography with flame ionization detection, were found to have a linear dynamic range to at least 250 micrograms/mL. While a number of different solvents were examined for the desorption of the analytes, methanol was found to be the best solvent for the recovery of all the analytes from 16-ply gauze pads, while 20 percent ethyl acetate in hexane was the preferred solvent for the styrene divinylbenzene-impregnated Empore filters. Limits of detection (LODs) for the analytes were comparable for both media. For Empore filters, the LODs were 50 micrograms/sample for atrazine, alachlor, chlorpyrifos, diazinon, and 2,4-D ethylhexy ester, with 30 micrograms/sample for metolachlor, and 80 micrograms/sample for cyanazine. For gauze pads, the LODs were 40 micrograms/sample for metolachlor, 50 micrograms/sample for alachlor, diazinon, and 2,4-D ethylhexy ester, 60 micrograms/sample for atrazine and chlorpyrifos, and 80 micrograms/sample for cyanazine. Both gauze pads and Empore filters gave quantitative recovery for all analytes except chlorpyrifos and 2,4-D ethylhexyl ester under ambient conditions (18 degrees C, 70% relative humidity) for up to 30 days; these analytes required refrigeration for that period to reach over 90 percent recovery. To assess the effect of environmental conditions on the recovery of the analytes, samples of each media were spiked at about 125 micrograms per analyte/sample (except cyanazine which was spiked at 190 micrograms) and challenged for 8 hr under high (80%) and low (20%) humidity and high (40 degrees C) and low (5 degrees C) temperature conditions in an environmental chamber. While the Empore samples gave quantitative recovery after being challenged, recovery from the gauze pads was affected by environmental conditions, especially high temperature. Recovery from gauze pads was below 30 percent for some analytes under high temperature/high humidity conditions. JF - Applied occupational and environmental hygiene AU - Lorberau, C D AU - Pride, J L AD - Division of Physical Sciences and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 946 EP - 950 VL - 15 IS - 12 SN - 1047-322X, 1047-322X KW - Insecticides KW - 0 KW - Solvents KW - Chlorpyrifos KW - JCS58I644W KW - Diazinon KW - YUS1M1Q929 KW - Index Medicus KW - Sensitivity and Specificity KW - Filtration KW - Administration, Cutaneous KW - Humans KW - Temperature KW - Specimen Handling KW - Humidity KW - Chlorpyrifos -- analysis KW - Diazinon -- analysis KW - Insecticides -- analysis KW - Occupational Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72512386?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+occupational+and+environmental+hygiene&rft.atitle=A+laboratory+comparison+of+two+media+for+use+in+the+assessment+of+dermal+exposure+to+pesticides.&rft.au=Lorberau%2C+C+D%3BPride%2C+J+L&rft.aulast=Lorberau&rft.aufirst=C&rft.date=2000-12-01&rft.volume=15&rft.issue=12&rft.spage=946&rft.isbn=&rft.btitle=&rft.title=Applied+occupational+and+environmental+hygiene&rft.issn=1047322X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Exposure to mercury vapor during the use of mercury carburetor synchronizers. AN - 72512246; 11147491 JF - Applied occupational and environmental hygiene AU - National Institute for Occupational Safety and Health AD - National Institute for Occupational Safety and Health Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 900 EP - 901 VL - 15 IS - 12 SN - 1047-322X, 1047-322X KW - Vehicle Emissions KW - 0 KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - Equipment Design KW - Air Pollution, Indoor -- analysis KW - Ventilation KW - Humans KW - Mercury -- analysis KW - Occupational Exposure -- analysis KW - Motor Vehicles KW - Vehicle Emissions -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72512246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+occupational+and+environmental+hygiene&rft.atitle=Exposure+to+mercury+vapor+during+the+use+of+mercury+carburetor+synchronizers.&rft.au=National+Institute+for+Occupational+Safety+and+Health&rft.aulast=National+Institute+for+Occupational+Safety+and+Health&rft.aufirst=&rft.date=2000-12-01&rft.volume=15&rft.issue=12&rft.spage=900&rft.isbn=&rft.btitle=&rft.title=Applied+occupational+and+environmental+hygiene&rft.issn=1047322X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls. AN - 72506645; 11221602 AB - Cytochrome P4501B1 (CYP1B1) is involved in the activation of many carcinogens and in the metabolism of steroid hormones, including 17beta-oestradiol (E2) and testosterone. We report a significant difference in the allele frequencies of two point mutations in the coding region of the CYP1B1 gene among Caucasian (n = 189), African-American (n = 52) and Chinese (Linxian) (n = 109) populations. A (C to G) transversion at position 1666 in exon 3, which results in an amino acid substitution of Leu432 to Val, was present in African-Americans with an allele frequency for Va1432 of 0.75, in Caucasians of 0.43, and in Chinese of 0.17. A (C to T) transition at position 1719 in exon 3, with no amino acid change (Asp449), appeared to be closely linked with the Val432 variant. Results using human lung microsomal preparations from individuals with the CYP1B1Val/Val and CYP1B1Leu/Leu genotypes indicate that Val432 variant may be a high activity allele and thus may contribute to the interindividual differences in CYP1B1 activity. Because CYP1B1 is involved in hormone and carcinogen metabolism, and given the disparate rates of prostate cancer among ethnic groups, we also evaluated the association of the CYP1B1 Leu432Val polymorphism with prostate cancer risk in a pilot case-control study. Among Caucasians, 34% of men with cancer (n = 50) were homozygous for the Val432 polymorphism, while only 12% of matched control subjects (n = 50) had this genotype. These preliminary data indicate that genetic polymorphisms in CYP1B1 might play an important role in human prostate carcinogenesis. JF - Pharmacogenetics AU - Tang, Y M AU - Green, B L AU - Chen, G F AU - Thompson, P A AU - Lang, N P AU - Shinde, A AU - Lin, D X AU - Tan, W AU - Lyn-Cook, B D AU - Hammons, G J AU - Kadlubar, F F AD - Division of Molecular Epidemiology, National Center for Toxicological Research, Jefferson, AR 72079, USA. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 761 EP - 766 VL - 10 IS - 9 SN - 0960-314X, 0960-314X KW - Cytochrome P-450 Enzyme System KW - 9035-51-2 KW - Steroid Hydroxylases KW - EC 1.14.- KW - Aryl Hydrocarbon Hydroxylases KW - EC 1.14.14.1 KW - CYP1B1 protein, human KW - Cytochrome P-450 CYP1A1 KW - Cytochrome P-450 CYP1B1 KW - estrogen 2-hydroxylase KW - Index Medicus KW - Humans KW - African Americans KW - Aged KW - Microsomes -- enzymology KW - Asian Continental Ancestry Group -- genetics KW - European Continental Ancestry Group -- genetics KW - Polymerase Chain Reaction KW - African Continental Ancestry Group -- genetics KW - Aged, 80 and over KW - China -- epidemiology KW - Adult KW - Middle Aged KW - Lung -- enzymology KW - Male KW - Continental Population Groups -- genetics KW - Polymorphism, Restriction Fragment Length KW - Cytochrome P-450 Enzyme System -- genetics KW - Prostatic Neoplasms -- genetics KW - Steroid Hydroxylases -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72506645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacogenetics&rft.atitle=Human+CYP1B1+Leu432Val+gene+polymorphism%3A+ethnic+distribution+in+African-Americans%2C+Caucasians+and+Chinese%3B+oestradiol+hydroxylase+activity%3B+and+distribution+in+prostate+cancer+cases+and+controls.&rft.au=Tang%2C+Y+M%3BGreen%2C+B+L%3BChen%2C+G+F%3BThompson%2C+P+A%3BLang%2C+N+P%3BShinde%2C+A%3BLin%2C+D+X%3BTan%2C+W%3BLyn-Cook%2C+B+D%3BHammons%2C+G+J%3BKadlubar%2C+F+F&rft.aulast=Tang&rft.aufirst=Y&rft.date=2000-12-01&rft.volume=10&rft.issue=9&rft.spage=761&rft.isbn=&rft.btitle=&rft.title=Pharmacogenetics&rft.issn=0960314X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-04-12 N1 - Date created - 2001-01-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Enzyme inhibition and enzyme-linked immunosorbent assay methods for carbamate pesticide residue analysis in fresh produce. AN - 72505820; 11131904 AB - An acetylcholinesterase inhibition method was employed for detection of 21 carbamate pesticides in bananas, peaches, strawberries, and tomatoes. Each of these four agricultural commodities was spiked with 0.1 to 10 ppm of each of the 21 carbamates and individual detection levels were determined. Similar responses and detection limits were observed for all four produce when tested for a given carbamate. The detection levels ranged from 0.1 ppm for carbofuran and 3-hydroxycarbofuran to 6 ppm for promecarb and aldicarb sulfoxide. These results are generally at or below the tolerances established by the Environmental Protection Agency for these commodities. Positive samples from the enzyme inhibition screening were also analyzed with the carbaryl-specific enzyme-linked immunosorbent assay (ELISA) kit. The detection limits for carbaryl and carbofuran were 2.0 ppb and 8.0 ppb, respectively. The other carbamates did not exhibit cross-reactivity even at high ppb levels. Thus, the enzyme inhibition assay and ELISA are simple and fast screening procedures for the detection of carbamate pesticide residues in food commodities. JF - Journal of food protection AU - Katsoudas, E AU - Abdelmesseh, H H AD - U.S. Food and Drug Administration, Northeast Regional Laboratory, Jamaica, New York 11433, USA. ekatsoud@ora.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 1758 EP - 1760 VL - 63 IS - 12 SN - 0362-028X, 0362-028X KW - Carbamates KW - 0 KW - Enzyme Inhibitors KW - Pesticide Residues KW - Index Medicus KW - Enzyme-Linked Immunosorbent Assay -- methods KW - Food Analysis KW - Food Contamination KW - Carbamates -- analysis KW - Pesticide Residues -- analysis KW - Fruit -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72505820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+food+protection&rft.atitle=Enzyme+inhibition+and+enzyme-linked+immunosorbent+assay+methods+for+carbamate+pesticide+residue+analysis+in+fresh+produce.&rft.au=Katsoudas%2C+E%3BAbdelmesseh%2C+H+H&rft.aulast=Katsoudas&rft.aufirst=E&rft.date=2000-12-01&rft.volume=63&rft.issue=12&rft.spage=1758&rft.isbn=&rft.btitle=&rft.title=Journal+of+food+protection&rft.issn=0362028X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-10-25 N1 - Date created - 2000-12-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Immunotoxicology: role of inflammation in chemical-induced hepatotoxicity. AN - 72472289; 11137622 AB - The liver, which is the major organ responsible for the metabolism of drugs and chemicals, is also the primary target organ for many toxic chemicals. Increasing evidence has indicated that inflammatory processes are intimately involved in chemical-induced hepatotoxic processes, and like other inflammatory diseases, such as autoimmunity, are responsible for producing mediators which can effect liver damage or repair. This review will summarize the authors' current understanding of how inflammatory processes influence hepatic pathology and repair following exposure to established hepatotoxic chemicals including carbon tetrachloride (CCl4), an industrial chemical, and acetaminophen (APAP), a widely used analgesic. JF - International journal of immunopharmacology AU - Luster, M I AU - Simeonova, P P AU - Gallucci, R M AU - Matheson, J M AU - Yucesoy, B AD - Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505-2888, USA. mluster@cdc.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 1143 EP - 1147 VL - 22 IS - 12 SN - 0192-0561, 0192-0561 KW - Inflammation Mediators KW - 0 KW - Index Medicus KW - Animals KW - Necrosis KW - Humans KW - Inflammation Mediators -- physiology KW - Chemical and Drug Induced Liver Injury -- pathology KW - Chemical and Drug Induced Liver Injury -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72472289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+immunopharmacology&rft.atitle=Immunotoxicology%3A+role+of+inflammation+in+chemical-induced+hepatotoxicity.&rft.au=Luster%2C+M+I%3BSimeonova%2C+P+P%3BGallucci%2C+R+M%3BMatheson%2C+J+M%3BYucesoy%2C+B&rft.aulast=Luster&rft.aufirst=M&rft.date=2000-12-01&rft.volume=22&rft.issue=12&rft.spage=1143&rft.isbn=&rft.btitle=&rft.title=International+journal+of+immunopharmacology&rft.issn=01920561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-22 N1 - Date created - 2001-02-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hazard surveillance for industrial magnetic fields: I. Walkthrough survey of ambient fields and sources. AN - 72470068; 11108783 AB - A walkthrough survey method was developed for measuring ambient magnetic fields (MFs) in industrial facilities as the first stage in hazard surveillance. This survey was designed to measure the mean and peak MF magnitudes at extremely low frequencies (ELFs), so that factories could be ranked by MF levels and prioritized for subsequent personal exposure monitoring. Sixty-two facilities from 13 Standard Industrial Classifications (SICs) with the highest monthly electric power usage were surveyed. To measure ambient MFs, a structured walkthrough survey with a special emphasis on workstations was conducted with an EMDEX-II meter in continuous operation, while MF sources were noted. The broadband MF data (40-800Hz) for each facility were summarized with the geometric mean (GM) and the average of the five highest readings (Hi-5). The range of the GM magnetic field magnitude was 0.04-1.61microT, where the maximum was measured at a steel mill operating large electric furnaces. Maximum values for specific sources were highly variable across and within facilities (Hi-5 range: 1.0-530 microT). Chemical and Allied Products (SIC 28) and Primary Metal Products (SIC 33) had facilities with GM and Hi-5 magnetic fields greater than any of the other industrial categories. However, the SIC categories were found to be poor predictors of the ambient MF in this sample of factories. A weak relationship was found between the facility-specific monthly electric power consumption and the GM magnetic field magnitude, but confidence limits were too broad to make meaningful exposure predictions from electric power data. Overall, 89% of the GMs were at or below 0.4 microT, consistent with most other studies that collected industrial MF exposure data. The walkthrough survey is a practical way of measuring ambient MFs in a large number of workplaces, and should be evaluated with personal measurements as a screening method for hazard surveillance. JF - The Annals of occupational hygiene AU - Methner, M M AU - Bowman, J D AD - National Institute for Occupational Safety and Health (Mail Stop R-19), 4676 Columbia Parkway, OH 45226, Cincinnati, USA. mmm5@cdc.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 603 EP - 614 VL - 44 IS - 8 SN - 0003-4878, 0003-4878 KW - Index Medicus KW - United States KW - Regression Analysis KW - Power Plants KW - Electric Power Supplies KW - Humans KW - Electronics KW - Metallurgy KW - Industry KW - Occupational Exposure -- prevention & control KW - Electromagnetic Fields KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72470068?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+occupational+hygiene&rft.atitle=Hazard+surveillance+for+industrial+magnetic+fields%3A+I.+Walkthrough+survey+of+ambient+fields+and+sources.&rft.au=Methner%2C+M+M%3BBowman%2C+J+D&rft.aulast=Methner&rft.aufirst=M&rft.date=2000-12-01&rft.volume=44&rft.issue=8&rft.spage=603&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+occupational+hygiene&rft.issn=00034878&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hazard surveillance for industrial magnetic fields: II. Field characteristics from waveform measurements. AN - 72465438; 11108784 AB - Magnetic field characteristics have been surveyed systematically in six factories with the Multiwave(R) II waveform capture instrument. These six facilities manufactured plastics, pharmaceuticals, cement, liquid air products, aluminum parts, and aluminum-framed filters. The study goals were to survey the physical characteristics of magnetic fields that may be related to biological effects under various interaction mechanisms and to relate those characteristics to the field's sources. From 59 waveform measurements at worker locations near sources, we calculated the extremely low frequency (ELF) and static field magnitudes, their frequency characteristics, and spatial characteristics of the 60Hz component. The RMS vector magnitude of the ELF magnetic field (the usual exposure metric in most studies) had medians ranging from 0.53 to 12.83 microT in the six factories. The static magnetic field magnitudes had medians of 24.2-46.2 microT, which is well below the geomagnetic reference field of 55.0 microT because of shielding from steel structures. The maximum static field was 128.6 microT near a DC motor. The frequency spectra of the most common fields is dominated by 60Hz, and has a median total harmonic distortion equal to 14.8%. The most common higher frequencies are the third, fifth, and second harmonics of 60Hz. However, magnetic fields in these workplaces had many other 60Hz harmonics and non-harmonic frequencies due particularly to electric motors and computer monitors. The 60Hz component magnetic fields have elliptical polarization with median axial ratio of 25.4%. The average proportion of the 60Hz component parallel to the static field vector was 51.5+/-3.0%, which indicates a significant trend towards perpendicular orientation between these two field components. In this survey of only six factories, the Multiwave(R) II measurements documented a wide diversity of complex magnetic field characteristics and non-sinusoidal waveforms. Although these characteristics are important to the various mechanisms postulated to explain biological effects, they are overlooked by the popular exposure assessment methods which only measure the ELF magnitude. Therefore, spot measurements with the Multiwave(R) II or similar waveform capture instruments are necessary for a complete magnetic field exposure assessment. JF - The Annals of occupational hygiene AU - Bowman, J D AU - Methner, M M AD - National Institute for Occupational Safety and Health (Mail Stop C-27), 4676 Columbia Parkway, OH 45226, Cincinnati, USA. jb60@cdc.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 615 EP - 633 VL - 44 IS - 8 SN - 0003-4878, 0003-4878 KW - Index Medicus KW - Reproducibility of Results KW - Humans KW - Occupational Exposure -- prevention & control KW - Electromagnetic Fields KW - Fourier Analysis KW - Environmental Monitoring -- methods KW - Environmental Monitoring -- instrumentation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72465438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+occupational+hygiene&rft.atitle=Hazard+surveillance+for+industrial+magnetic+fields%3A+II.+Field+characteristics+from+waveform+measurements.&rft.au=Bowman%2C+J+D%3BMethner%2C+M+M&rft.aulast=Bowman&rft.aufirst=J&rft.date=2000-12-01&rft.volume=44&rft.issue=8&rft.spage=615&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+occupational+hygiene&rft.issn=00034878&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Cognitive tests: interpretation for neurotoxicity? (Workshop summary). AN - 72437295; 11099635 AB - The appropriate use and interpretation of cognitive tests presents important challenges to the toxicologist and to the risk assessor. For example, intelligence cannot be measured directly; rather intelligence is quantified indirectly by scoring responses (i.e., behaviors) to specific situations (problems). This workshop, "Cognitive Tests: Interpretation for Neurotoxicity?" provided an overview on the types of cognitive tests available and described approaches by which the validity of such tests can be assessed. Unlike many tools available to the toxicologist, cognitive tests have a particular advantage. Being noninvasive and species-neutral, the same test can be performed in different mammalian species. This enhances one's ability to assess the validity of test results. Criteria for test validity include comparable responses across species as well as similar disruption by the same neurotoxicant across species. Test batteries, such as the Operant Test Battery, have indicated remarkable similarity between monkeys and children with respect to performance of certain tasks involving, for example, short-term memory. Still, there is a need for caution in interpretation of such tests. In particular, cognitive tests, especially when performed in humans, are subject to confounding by a range of factors, including age, gender, and, in particular, education. Moreover, the ability of such tests to reflect intelligence must be considered. Certain aspects of intelligence, such as the ability to plan or carry out specific tasks, are not well reflected by many of the standard tests of cognition. Nonetheless, although still under development, cognitive tests do hold promise for reliably predicting neurotoxicity in humans. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Slikker, W AU - Beck, B D AU - Cory-Slechta, D A AU - Paule, M G AU - Anger, W K AU - Bellinger, D AD - National Center for Toxicological Research, Division of Neurotoxicology, 3900 NCTR Road, Jefferson, Arkansas 72079, USA. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 222 EP - 234 VL - 58 IS - 2 SN - 1096-6080, 1096-6080 KW - Index Medicus KW - Behavior, Animal -- drug effects KW - Animals KW - Humans KW - Cognition -- drug effects KW - Brain -- drug effects KW - Toxicology -- methods KW - Brain -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72437295?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Cognitive+tests%3A+interpretation+for+neurotoxicity%3F+%28Workshop+summary%29.&rft.au=Slikker%2C+W%3BBeck%2C+B+D%3BCory-Slechta%2C+D+A%3BPaule%2C+M+G%3BAnger%2C+W+K%3BBellinger%2C+D&rft.aulast=Slikker&rft.aufirst=W&rft.date=2000-12-01&rft.volume=58&rft.issue=2&rft.spage=222&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-04 N1 - Date created - 2001-01-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Occupational skin diseases. AN - 72407457; 11072293 AB - Primary care physicians will likely see a wide variety of occupational skin diseases in their practices, including allergic contact dermatitis, irritant contact dermatitis, contact urticaria, a variety of infectious diseases, and skin cancers. The ideal role of a medical practitioner involved in occupational dermatology is not only to diagnose and treat patients, but also to determine the cause of the occupational skin disease and to make recommendations for its prevention. Making the diagnosis and offering treatment, determining the cause, and recommending measures can be difficult undertakings. JF - Primary care AU - Lushniak, B D AD - US Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluations, and Field Studies, Cincinnati, Ohio, USA. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 895 EP - 916 VL - 27 IS - 4 SN - 0095-4543, 0095-4543 KW - Index Medicus KW - Occupational Health KW - Cost of Illness KW - Public Health Practice KW - Risk Factors KW - Humans KW - Primary Prevention -- methods KW - United States -- epidemiology KW - Dermatitis, Occupational -- diagnosis KW - Dermatitis, Occupational -- etiology KW - Dermatology -- methods KW - Physician's Role KW - Primary Health Care -- methods KW - Dermatitis, Occupational -- therapy KW - Occupational Medicine -- methods KW - Dermatitis, Occupational -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72407457?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Primary+care&rft.atitle=Occupational+skin+diseases.&rft.au=Lushniak%2C+B+D&rft.aulast=Lushniak&rft.aufirst=B&rft.date=2000-12-01&rft.volume=27&rft.issue=4&rft.spage=895&rft.isbn=&rft.btitle=&rft.title=Primary+care&rft.issn=00954543&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Development of a fungus-specific PCR assay for detecting low-level fungi in an indoor environment. AN - 70772997; 11090263 AB - A fungus-specific PCR assay using only one primer set has been developed for detecting indoor fungi. Four fungal primer sets, NS3/NS4, NS5/NS6, FF1/FR1 and FF2/FR1, were tested with DNA from humans, rats, mice, bacteria, pollens and six commonly found fungal species (Alternaria chamydospora, Aspergillus flavus, Candida famata, Cladosporium fermentans, Penicillium chrycoIgenum and Stachybotrys chartarum). Results indicated that, although all four primer sets could amplify the fungal DNA, only FF2/FR1 demonstrated no cross-amplification with non-fungal DNA. In addition, these amplified fragments were sequenced to ensure that they indeed matched known fungal DNA sequences. Furthermore, besides the tested fungi, eighteen more genera of fungal sequences were examined and found to match the FF2/FR1. Here, the method of bead-beating was identified as the most effective way for spore breakage and fungal DNA release. The PCR amplification efficiency and potential inhibition were examined using different process solutions and preparation procedures. It was found that, when using 20% nutrient media and homogenization-first procedure, a higher amplification efficiency with less inhibition was achieved. Although positive bands were observed at 0.2 fungal spore/reaction using the homogenization-first procedure, the sensitivity of this assay would be two fungal spores/reaction for environmental samples. Copyright 2000 Academic Press. JF - Molecular and cellular probes AU - Zhou, G AU - Whong, W Z AU - Ong, T AU - Chen, B AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, Morgantown, WV 26505-2845, USA. Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 339 EP - 348 VL - 14 IS - 6 SN - 0890-8508, 0890-8508 KW - DNA Primers KW - 0 KW - DNA, Fungal KW - DNA, Ribosomal KW - Index Medicus KW - Sensitivity and Specificity KW - Rats KW - Pollen -- genetics KW - Animals KW - Humans KW - Spores, Fungal -- genetics KW - Electrophoresis, Agar Gel KW - Mice KW - DNA Primers -- chemistry KW - DNA, Fungal -- isolation & purification KW - DNA, Fungal -- analysis KW - DNA, Ribosomal -- isolation & purification KW - Air Pollution, Indoor -- analysis KW - Polymerase Chain Reaction -- methods KW - Fungi -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70772997?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+and+cellular+probes&rft.atitle=Development+of+a+fungus-specific+PCR+assay+for+detecting+low-level+fungi+in+an+indoor+environment.&rft.au=Zhou%2C+G%3BWhong%2C+W+Z%3BOng%2C+T%3BChen%2C+B&rft.aulast=Zhou&rft.aufirst=G&rft.date=2000-12-01&rft.volume=4&rft.issue=&rft.spage=1339&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+...+North+American+Rock+Mechanics+Symposium&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Multiplex PCR for detection of trait and virulence factors in enterohemorrhagic Escherichia coli serotypes. AN - 70764345; 11090262 AB - A multiplex PCR assay was developed which allowed the simultaneous detection of five trait genes or virulence markers in enterohemorrhagic Escherichia coli (EHEC) serotypes. A primer pair, designed to detect a single base-pair mutation in the uidA gene, is specific only for the prototypic EHEC of O157:H7 serotype and its toxigenic, non-motile variants. In a similar way, primers to the eaeA gene of the gamma-intimin derivative specifically detects strains in the EHEC 1 clonal group, which consists mostly of O157:H7 and some O55:H7 serotypes. The other three primer pairs, specific for stx1, stx2 and both variants of ehxA genes, will detect the presence of these virulence genes in all EHEC serotypes. Analysis of 34 strains, including various serotypes of EHEC, Shiga toxin-producing E. coli and enteropathogenic E. coli, confirmed that the multiplex PCR assay detected the presence of these genes in a manner consistent with the known genotype of each respective strains. Copyright 2000 Academic Press. JF - Molecular and cellular probes AU - Feng, P AU - Monday, S R AD - Division of Microbiological Studies, US Food and Drug Administration, Washington DC 20204, USA. pfeng@cfsan.fda.gov Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 333 EP - 337 VL - 14 IS - 6 SN - 0890-8508, 0890-8508 KW - Bacterial Proteins KW - 0 KW - DNA Primers KW - Escherichia coli Proteins KW - Hemolysin Proteins KW - Hlya protein, E coli KW - Shiga Toxin 2 KW - Shiga Toxin KW - 75757-64-1 KW - Index Medicus KW - Polymerase Chain Reaction KW - Genetic Variation KW - Electrophoresis, Agar Gel KW - Serotyping KW - DNA Primers -- chemistry KW - Shiga Toxin 2 -- genetics KW - Bacterial Proteins -- genetics KW - Virulence -- genetics KW - Shiga Toxin -- genetics KW - Multifactorial Inheritance -- genetics KW - Hemolysin Proteins -- genetics KW - Escherichia coli O157 -- immunology KW - Escherichia coli O157 -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70764345?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+and+cellular+probes&rft.atitle=Multiplex+PCR+for+detection+of+trait+and+virulence+factors+in+enterohemorrhagic+Escherichia+coli+serotypes.&rft.au=Feng%2C+P%3BMonday%2C+S+R&rft.aulast=Feng&rft.aufirst=P&rft.date=2000-12-01&rft.volume=14&rft.issue=6&rft.spage=333&rft.isbn=&rft.btitle=&rft.title=Molecular+and+cellular+probes&rft.issn=08908508&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-25 N1 - Date created - 2001-01-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Club Drugs. The DAWN Report. AN - 62349779; ED448388 AB - This report was prepared in response to requests from the media, law enforcement, and community leaders for information about club drugs. By being able to utilize statistics from hospital emergency departments and by compiling statistics on drug-related deaths, the Drug Abuse Warning Network (DAWN) is able to alert parents, educators, and others involved in the education of young adults about the danger of these drugs. An increased interest in club drugs follows recent publications of the use and effects of these drugs. Six drugs known as club drugs are highlighted in this report. They are: (1) d-lysergic acid diethylamide (LSD); (2) Gamma-hydroxy butyrate (GHB); (3) Ketamine; (4) methamphetamine; (5) methylenedioxymethamphetamine (Ecstasy); and (6) Rohypnol. According to DAWN, most emergency department episodes involving club drugs also involve other drugs. Club drugs are predominately used by adults under 25 years of age and whites make up 61% of all emergency department episodes. The report contains background information about the drugs, followed by trends in drug use for the years 1994-1998. Tables are used to describe trends in club drugs in multi-drug emergency department visits, and drug related deaths. Demographic characteristics of emergency department cases are described along with at look at the metropolitan areas where they occurred. (JDM) Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 11 KW - Emergency Medical Services KW - ERIC, Resources in Education (RIE) KW - Demography KW - Prevention KW - Elementary Secondary Education KW - Drug Education KW - Young Adults KW - Illegal Drug Use KW - Adolescents KW - Hospitals KW - Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62349779?accountid=14244 LA - English DB - ERIC N1 - Availability - Level 1 - Available online, if indexed January 1993 onward N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - The study of TSP, PM (sub 2.5-10) and PM (sub 2.5) during Taiwan Chi-Chi earthquake in the traffic site of central Taiwan, Taichung AN - 52269635; 2001-015836 JF - Chemosphere (Oxford) AU - Fang, Guor-Cheng AU - Chang, Cheng-Nan AU - Wang, Nai-Phon AU - Wu, Yuh-Shen AU - Wang, Vicky AU - Fu, Peter Pi-Cheng AU - Cheng, Chii-Dong AU - Chen, Shun-Chin AU - Lin, Don-Yee Y1 - 2000/12// PY - 2000 DA - December 2000 SP - 1727 EP - 1731 PB - Pergamon, Oxford VL - 41 IS - 11 SN - 0045-6535, 0045-6535 KW - central Taiwan KW - concentration KW - Taiwan KW - particulate matter KW - Far East KW - Taichung Taiwan KW - pollution KW - suspended materials KW - sampling KW - Chi-Chi earthquake 1999 KW - air KW - Asia KW - earthquakes KW - instruments KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52269635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere+%28Oxford%29&rft.atitle=The+study+of+TSP%2C+PM+%28sub+2.5-10%29+and+PM+%28sub+2.5%29+during+Taiwan+Chi-Chi+earthquake+in+the+traffic+site+of+central+Taiwan%2C+Taichung&rft.au=Fang%2C+Guor-Cheng%3BChang%2C+Cheng-Nan%3BWang%2C+Nai-Phon%3BWu%2C+Yuh-Shen%3BWang%2C+Vicky%3BFu%2C+Peter+Pi-Cheng%3BCheng%2C+Chii-Dong%3BChen%2C+Shun-Chin%3BLin%2C+Don-Yee&rft.aulast=Fang&rft.aufirst=Guor-Cheng&rft.date=2000-12-01&rft.volume=41&rft.issue=11&rft.spage=1727&rft.isbn=&rft.btitle=&rft.title=Chemosphere+%28Oxford%29&rft.issn=00456535&rft_id=info:doi/ L2 - http://www.sciencedirect.com/science/journal/00456535 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2001-01-01 N1 - Number of references - 8 N1 - Document feature - illus. incl. 4 tables, sketch maps N1 - Last updated - 2012-06-07 N1 - CODEN - CMSHAF N1 - SubjectsTermNotLitGenreText - air; Asia; central Taiwan; Chi-Chi earthquake 1999; concentration; earthquakes; Far East; instruments; particulate matter; pollution; sampling; suspended materials; Taichung Taiwan; Taiwan ER - TY - JOUR T1 - Evaluation of Nonisotopic DNA Hybridization Methods for Detection of the tdh Gene of Vibrio parahaemolyticus AN - 18389565; 5382049 AB - Production of the thermostable direct hemolysin (TDH) by Vibrio parahaemolyticus is associated with pathogenicity of the organism and is encoded by the tdh gene. The timely resolution of seafood-associated outbreaks requires rapid and accurate detection of pathogenic V. parahaemolyticus. The specificity of alkaline phosphatase- and digoxigenin-labeled tdh gene probes was evaluated against 61 strains of V. parahaemolyticus (including isolates from recent outbreaks involving oysters from the Pacific Northwest, Texas, and New York), 85 strains of other vibrios, and 7 strains of non-vibrio species from clinical and environmental sources. The probes were specific for detection of the V. parahaemolyticus tdh gene. JF - Journal of Food Protection AU - McCarthy, SA AU - DePaola, A AU - Cook, D W AU - Kaysner, CA AU - Hill, W E AD - Gulf Coast Seafood Laboratory, U.S. Food and Drug Administration, Dauphin Island, AL 36528, USA Y1 - 2000/12// PY - 2000 DA - Dec 2000 SP - 1660 EP - 1664 VL - 63 IS - 12 SN - 0362-028X, 0362-028X KW - digoxigenin KW - outbreaks KW - tdh gene KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - A 01116:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18389565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+...+North+American+Rock+Mechanics+Symposium&rft.atitle=Rock+strength+determination+using+a+new+true+triaxial+loading+apparatus%2C+and+the+inadequacy+of+Mohr-type+failure+criteria&rft.au=Chang%2C+C%3BHaimson%2C+Bezalel+C&rft.aulast=Chang&rft.aufirst=C&rft.date=2000-01-01&rft.volume=4&rft.issue=&rft.spage=1321&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+...+North+American+Rock+Mechanics+Symposium&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Bird nesting ecology in a forest defoliated by gypsy moths AN - 17839888; 4876958 AB - Acadian Flycatcher (Empidonax virescens, n = 55), Indigo Bunting (Passerina cyanea, n = 60), Eastern Towhee (Pipilo erythrophthalmus, n = 41), and Wood Thrush (Hylocichla mustelina, n = 62) nests were monitored during 1995-1996 in the eastern panhandle of West Virginia, at the Sleepy Creek Wildlife Management Area. The objective of this study was to relate the outcomes of bird nests to surrounding habitat characteristics in an area that experienced heavy tree mortality from prior defoliation by the gypsy moth (Lymantria dispar). Large (> 22.9 cm dbh) standing snags in the nest patch were not associated with nest failure for any of the four bird species. Very large diameter (> 38.1 cm dbh) live trees and snags and reduced canopy cover increased the chances of Brown-headed Cowbird (Molothrus ater) parasitism only for Indigo Buntings. Nest patches of all four species differed in vegetation characteristics from random plots in similar habitat, typically by having greater densities of species' preferred nesting substrate in the nest patch. Gypsy moth defoliation, which can result in an increase in snags and opened canopy, is not likely to be a devastating ecological event for shrub and sub-canopy nesting avian species, and can create more nesting habitat for many species that use a dense forest understory. JF - Wilson Bulletin AU - Bell, J L AU - Whitmore, R C AD - Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Safety Research, 1095 Willowdale Road, MS/P-1133, Morgantown, WV 26505-2888, USA, jbell@cdc.gov Y1 - 2000/12// PY - 2000 DA - Dec 2000 SP - 524 EP - 531 VL - 112 IS - 4 SN - 0043-5643, 0043-5643 KW - Gypsy Moth KW - Acadian flycatcher KW - Indigo bunting KW - Wood thrush KW - Eastern towhee KW - Lepidoptera KW - Aves KW - USA, West Virginia KW - Entomology Abstracts; Ecology Abstracts KW - Pest attack KW - Passerina cyanea KW - Hylocichla mustelina KW - Forests KW - Breeding KW - Empidonax virescens KW - Defoliation KW - Population levels KW - Pipilo erythrophthalmus KW - Lymantria dispar KW - D 04671:Birds KW - Z 05205:Populations & general ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17839888?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Wilson+Bulletin&rft.atitle=Bird+nesting+ecology+in+a+forest+defoliated+by+gypsy+moths&rft.au=Bell%2C+J+L%3BWhitmore%2C+R+C&rft.aulast=Bell&rft.aufirst=J&rft.date=2000-12-01&rft.volume=112&rft.issue=4&rft.spage=524&rft.isbn=&rft.btitle=&rft.title=Wilson+Bulletin&rft.issn=00435643&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Lymantria dispar; Empidonax virescens; Pipilo erythrophthalmus; Passerina cyanea; Hylocichla mustelina; Population levels; Breeding; Defoliation; Forests; Pest attack ER - TY - JOUR T1 - Characterization of Chloramphenicol and Florfenicol Resistance in Escherichia coli Associated with Bovine Diarrhea AN - 17839135; 4869779 AB - Florfenicol, a veterinary fluorinated analog of thiamphenicol, is approved for treatment of bovine respiratory pathogens in the United States. However, florfenicol resistance has recently emerged among veterinary Escherichia coli isolates incriminated in bovine diarrhea. The flo gene, which confers resistance to florfenicol and chloramphenicol, has previously been identified in Photobacterium piscicida and Salmonella enterica serovar Typhimurium DT104. The flo gene product is closely related to the CmlA protein identified in Pseudomonas aeruginosa. The cmlA gene confers nonenzymatic chloramphenicol resistance via an efflux mechanism. Forty-eight E. coli isolates recovered from calves with diarrhea, including 41 that were both chloramphenicol and florfenicol resistant, were assayed for the presence of both flo and cmlA genes. Forty-two of the 44 isolates for which florfenicol MICs were >=16 mu g/ml were positive via PCR for the flo gene. All E. coli isolates for which florfenicol MICs were =32 mu g/ml. Additionally, eight isolates were positive for both flo and cmlA, and both florfenicol and chloramphenicol MICs for these isolates were >=64 mu g/ml. DNA sequence analysis of the E. coli flo gene demonstrated 98% identity to the published GenBank sequences of both serovar Typhimurium flo sub(St) and P. piscicida pp-flo. The flo gene was identified on high-molecular-weight plasmids of approximately 225 kb among the majority of florfenicol-resistant E. coli isolates. However, not all of the florfenicol-resistant E. coli isolates tested contained the large flo-positive plasmids. This suggests that several of the E. coli isolates may possess a chromosomal flo gene. The E. coli flo gene specifies nonenzymatic cross-resistance to both florfenicol and chloramphenicol, and its presence among bovine E. coli isolates of diverse genetic backgrounds indicates a distribution much wider than previously thought. JF - Journal of Clinical Microbiology AU - White, D G AU - Hudson, C AU - Maurer, J J AU - Ayers, S AU - Zhao, S AU - Lee, MD AU - Bolton, L AU - Foley, T AU - Sherwood, J AD - Office of Research, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD 20708, dwhite@cvm.fda.gov Y1 - 2000/12// PY - 2000 DA - Dec 2000 SP - 4593 EP - 4598 VL - 38 IS - 12 SN - 0095-1137, 0095-1137 KW - isolates KW - cattle KW - florfenicol KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Chloramphenicol KW - Diarrhea KW - Escherichia coli KW - Antibiotic resistance KW - A 01064:Microbial resistance KW - J 02795:Antibiotic resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17839135?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Characterization+of+Chloramphenicol+and+Florfenicol+Resistance+in+Escherichia+coli+Associated+with+Bovine+Diarrhea&rft.au=White%2C+D+G%3BHudson%2C+C%3BMaurer%2C+J+J%3BAyers%2C+S%3BZhao%2C+S%3BLee%2C+MD%3BBolton%2C+L%3BFoley%2C+T%3BSherwood%2C+J&rft.aulast=White&rft.aufirst=D&rft.date=2000-12-01&rft.volume=38&rft.issue=12&rft.spage=4593&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Escherichia coli; Antibiotic resistance; Diarrhea; Chloramphenicol ER - TY - JOUR T1 - Developmental Neurotoxicity of Endocrine Disrupters: Focus on Estrogens AN - 17820789; 4856601 AB - A number of different environmental compounds are proposed to interact with the endocrine system (i.e., endocrine disrupters). Many of these have estrogenic effects in vitro and/or in vivo. Recent reviews have focused attention on the need for assessing the neurotoxicity of these compounds following developmental exposure. This attention comes in part from the literature on the effects of developmental exposure to exogenous estrogen on later behavioral and neuropathological alterations. A review of the ongoing neurobehavioral and neuropathological studies at the National Center for Toxicological Research on four such estrogen mimics (genistein, methoxychlor, nonylphenol, and ethinyl estradiol) is presented with results indicating that intake of a sodium solution is sensitive to these estrogen mimics. Developmental dietary exposure in male and female rats resulted in increased consumption of the sodium solution. Volume of the sexually dimorphic nucleus of the medial preoptic area was reduced by genistein, nonylphenol, and ethinyl estradiol exposure in males. The regulatory impact of these data and the directions for future research are discussed. JF - Neurotoxicology AU - Ferguson, SA AU - Scallet, A C AU - Flynn, K M AU - Meredith, J M AU - Schwetz, BA AD - Division of Neurotoxicology, National Center for Toxicological Research, FDA, 3900 NCTR Road, HFT-132, Jefferson, AR 72079, USA, sferguson@nctr.fda.gov Y1 - 2000/12// PY - 2000 DA - Dec 2000 SP - 947 EP - 956 PB - Intox Press VL - 21 IS - 6 SN - 0161-813X, 0161-813X KW - rats KW - endocrine disruptors KW - ethinyl estradiol KW - genistein KW - methoxychlor KW - methoxyclor KW - nonphenol KW - nonyl phenol KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Estrogens KW - Reviews KW - Neurotoxicity KW - Steroid hormones KW - Endocrine system KW - Genistein KW - N3 11104:Mammals (except primates) KW - X 24240:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17820789?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology&rft.atitle=Developmental+Neurotoxicity+of+Endocrine+Disrupters%3A+Focus+on+Estrogens&rft.au=Ferguson%2C+SA%3BScallet%2C+A+C%3BFlynn%2C+K+M%3BMeredith%2C+J+M%3BSchwetz%2C+BA&rft.aulast=Ferguson&rft.aufirst=SA&rft.date=2000-12-01&rft.volume=21&rft.issue=6&rft.spage=947&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology&rft.issn=0161813X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Neurotoxicity; Reviews; Estrogens; Endocrine system; Genistein; Steroid hormones ER - TY - JOUR T1 - The Determination of Phosphorus in Haemophilus influenzae Type b Conjugate Vaccines by Inductively Coupled Plasma-Atomic Emission Spectrometry AN - 17817904; 4858178 AB - This study describes a method for the determination of phosphorus in lyophilized Haemophilus influenzae type b conjugate vaccines by inductively coupled plasma-atomic emission spectroscopy (ICP-AES). The concentration of polysaccharide is directly related to the concentration of phosphorus as measured in the laboratory. Phosphorus is present in the polyribosyl-ribitol phosphate (PRP) group of the Haemophilus influenzae type b conjugate vaccine. The repeating unit of PRP is 3-B-D ribose[1-1]ribitol-5-phosphate. Phosphorus in the final container is measured in mu g per dose. The amount of PRP is calculated from this and reported in mu g per dose. The Haemophilus influenzae type b conjugate vaccine was analyzed for phosphorus content within the range of 1.34 to 2.02 mu g phosphorus per ml. The relative difference of phosphorus concentrations determined by the ICP-AES method from the phosphorus concentrations determined by the traditional colorimetric molybdate method ranged from 2.2 to 10.6%. Phosphorus spike recovery for the vaccine ranged from 93 to 99% (1.93 plus or minus 0.13 mu g P/ml). The phosphorus determination of NIST SRM 3139 phosphorus spectrometric solution differed by 3.0% from the certified phosphorus value (10.00 mg P/ml). Copyright 2000 United States Government JF - Biologicals AU - Swartz, LA AU - Progar, J J AU - May, J C AD - Center for Biologics Evaluation and Research, United States Food and Drug Administration, Rockville, 20852, MD, U.S.A. Y1 - 2000/12// PY - 2000 DA - Dec 2000 SP - 227 EP - 231 PB - Academic Press VL - 28 IS - 4 SN - 1045-1056, 1045-1056 KW - Haemophilus influenzae KW - Biotechnology and Bioengineering Abstracts; Microbiology Abstracts B: Bacteriology; Medical and Pharmaceutical Biotechnology Abstracts KW - Phosphorus KW - Vaccines KW - Spectrometry KW - J 02834:Vaccination and immunization KW - W3 33365:Vaccines (other) KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17817904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biologicals&rft.atitle=The+Determination+of+Phosphorus+in+Haemophilus+influenzae+Type+b+Conjugate+Vaccines+by+Inductively+Coupled+Plasma-Atomic+Emission+Spectrometry&rft.au=Swartz%2C+LA%3BProgar%2C+J+J%3BMay%2C+J+C&rft.aulast=Swartz&rft.aufirst=LA&rft.date=2000-12-01&rft.volume=28&rft.issue=4&rft.spage=227&rft.isbn=&rft.btitle=&rft.title=Biologicals&rft.issn=10451056&rft_id=info:doi/10.1006%2Fbiol.2000.0261 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Haemophilus influenzae; Spectrometry; Vaccines; Phosphorus DO - http://dx.doi.org/10.1006/biol.2000.0261 ER - TY - JOUR T1 - Effects of Benzothiazole on the Xenobiotic Metabolizing Enzymes and Metabolism of Acetaminophen AN - 17782007; 4830660 AB - Benzothiazole (BT) is present in tobacco smoke and widely used for industrial and pharmaceutical purposes. In this study we have investigated the influence of BT on the activities of hepatic cytochrome P450 monooxygenases (P450s) and UDP-glucuronyltransferase (UDP-GT), sulphotransferase and glutathione-S-transferase (GST) in male Sprague-Dawley rats. We also examined if BT would change the metabolism and toxification of acetaminophen (AA) through modulation of metabolizing enzymes. Benzothiazole (1 mmol kg super(-1), p.o., 5 days) markedly increased the enzyme activities of P4501A1, 1A2, 2B1, 3A4, 2E1, UDP-GT and GST in liver. Pretreatment with BT significantly decreased the amount of total AA recovered in bile to 68.5% of controls, mainly as a consequence of reduced AA-glucuronide conjugate (35.3% of controls), whereas the AA-glutathione conjugate (AA-GS) was augmented to 1.6-fold. After pretreatment with BT, potentiation of the hepatotoxicity by AA (400 mg kg super(-1), i.p., 24 h) was observed by measuring serum alanine aminotransferase activities in ICR mice. These results indicate that: BT is a potent inducer of P450s and phase II metabolizing enzymes; and the increase of AA-GS conjugate and aggravation of AA hepatotoxicity by BT may be related to induction of P450s. JF - Journal of Applied Toxicology AU - Seo, Kyung Won AU - Park, M AU - Kim, Jun Gyou AU - Kim, Tae Wan AU - Kim, Hyo Jung AD - Toxicology Department, National Institute of Toxicological Research, Korea Food and Drug Administration, 5 Nokbundong, Eunpyunggu, Seoul 122-020, Korea Y1 - 2000/12// PY - 2000 DA - Dec 2000 SP - 427 EP - 430 VL - 20 IS - 6 SN - 0260-437X, 0260-437X KW - rats KW - benzothiazole KW - cytochrome P450 KW - Toxicology Abstracts KW - Drug metabolism KW - Xenobiotics KW - Acetaminophen KW - X 24114:Metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17782007?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Toxicology&rft.atitle=Effects+of+Benzothiazole+on+the+Xenobiotic+Metabolizing+Enzymes+and+Metabolism+of+Acetaminophen&rft.au=Seo%2C+Kyung+Won%3BPark%2C+M%3BKim%2C+Jun+Gyou%3BKim%2C+Tae+Wan%3BKim%2C+Hyo+Jung&rft.aulast=Seo&rft.aufirst=Kyung&rft.date=2000-12-01&rft.volume=20&rft.issue=6&rft.spage=427&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Toxicology&rft.issn=0260437X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Acetaminophen; Drug metabolism; Xenobiotics ER - TY - JOUR T1 - Epidemiologic investigation of respiratory morbidity at a nylon flock plant AN - 17730550; 4803183 AB - Background: A cluster of biopsy-confirmed interstitial lung disease among workers at a nylon flock plant led to a request for National Institute for Occupational Safety and Health investigators to conduct a health hazard evaluation. Methods: Part of the overall evaluation, reported here, involved a cross-sectional medical survey of current employees. The survey consisted of a questionnaire, spirometry and diffusing capacity testing, and chest radiograph. Results: Workers assigned to production and maintenance jobs reported frequent eye and throat irritation, respiratory symptoms, and systemic symptoms (i.e., generalized aches and fevers). Most reported improvement when away from work. Frequent respiratory/systemic symptom prevalence was significantly associated with departmental category, with days and hours worked per week, and with working on a flocking range. Compared to asymptomatic workers, symptomatic workers had similar mean ratios of forced expiratory volume in one second to forced vital capacity, but lower mean percent of predicted values for both forced vital capacity and diffusing capacity. All acceptable chest radiographs were classified as category 0 for small opacities. Conclusions: Findings of this study, along with those from studies reported elsewhere, implicate occupational exposure to flock-associated dust as a significant respiratory health hazard at this plant. JF - American Journal of Industrial Medicine AU - Washko, R M AU - Day, B AU - Parker, JE AU - Castellan, R M AU - Kreiss, K AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA, kxk2@cdc.gov Y1 - 2000/12// PY - 2000 DA - Dec 2000 SP - 628 EP - 638 VL - 38 IS - 6 SN - 0271-3586, 0271-3586 KW - man KW - nylon KW - respiratory tract diseases KW - Toxicology Abstracts; Health & Safety Science Abstracts; Pollution Abstracts KW - Dust KW - Morbidity KW - Respiratory tract diseases KW - Epidemiology KW - Occupational exposure KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24152:Chronic exposure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17730550?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Epidemiologic+investigation+of+respiratory+morbidity+at+a+nylon+flock+plant&rft.au=Washko%2C+R+M%3BDay%2C+B%3BParker%2C+JE%3BCastellan%2C+R+M%3BKreiss%2C+K&rft.aulast=Washko&rft.aufirst=R&rft.date=2000-12-01&rft.volume=38&rft.issue=6&rft.spage=628&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Morbidity; Occupational exposure; Dust; Epidemiology; Respiratory tract diseases ER - TY - JOUR T1 - Strategies and testing methods for identifying mutagenic risks. AN - 72477773; 11113464 AB - The evolution of testing strategies and methods for identification of mutagenic agents is discussed, beginning with the concern over potential health and population effects of chemical mutagens in the late 1940s that led to the development of regulatory guidelines for mutagenicity testing in the 1970s and 1980s. Efforts to achieve international harmonization of mutagenicity testing guidelines are summarized, and current issues and needs in the field are discussed, including the need for quantitative methods of mutagenic risk assessment, dose-response thresholds, indirect mechanisms of mutagenicity, and the predictivity of mutagenicity assays for carcinogenicity in vivo. Speculation is offered about the future of mutagenicity testing, including possible near-term changes in standard test batteries and the longer-term roles of expression profiling of damage-response genes, in vivo mutagenicity testing methods, and models that better account for differences in metabolism between humans and laboratory model systems. JF - Mutation research AU - MacGregor, J T AU - Casciano, D AU - Müller, L AD - FDA Center for Drug Evaluation and Research, 5600 Fishers Lane, Rockville, MD 20857, USA. macgregorj@cder.fda.gov Y1 - 2000/11/20/ PY - 2000 DA - 2000 Nov 20 SP - 3 EP - 20 VL - 455 IS - 1-2 SN - 0027-5107, 0027-5107 KW - Carcinogens KW - 0 KW - Mutagens KW - Index Medicus KW - Humans KW - Carcinogenicity Tests -- standards KW - Mutagenicity Tests -- standards KW - Risk Assessment -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72477773?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mutation+research&rft.atitle=Strategies+and+testing+methods+for+identifying+mutagenic+risks.&rft.au=MacGregor%2C+J+T%3BCasciano%2C+D%3BM%C3%BCller%2C+L&rft.aulast=MacGregor&rft.aufirst=J&rft.date=2000-11-20&rft.volume=455&rft.issue=1-2&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Mutation+research&rft.issn=00275107&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-26 N1 - Date created - 2001-01-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein. The role of hsp90. AN - 72435983; 10961990 AB - The aryl hydrocarbon receptor (AhR) has been shown to interact with an immunophilin-like molecule known as AhR-interacting protein (AIP) and to enhance AhR function. We show here that AIP associates with AhR homologues from mouse and fish, which can bind ligands such as dioxin, but nonligand binding homologues from Caenorhabditis elegans or Drosophila do not bind to AIP. However, a minimal ligand-binding domain of the AhR is incapable of binding AIP. The binding of AIP to AhR in reticulocyte lysate shows several of the characteristics of an hsp90-dependent process, including sensitivity to geldanamycin and temperature and a requirement for ATP or nonhydrolyzable analogues. Purified AIP binds to the C terminus of hsp90, and mutation of a conserved basic residue in the tetratricopeptide repeats of AIP (K266A, analogous to K97A in protein phosphatase 5) abolishes binding to hsp90. Mutation of K266A in AIP reduces binding to AhR by 75-80%; the geldanamycin sensitivity of this complex shows that AhR stabilizes the AIP-hsp90-AhR complex. The alpha-helical C terminus of AIP, which is outside the tetratricopeptide repeat domain, is absolutely required for binding to AhR as shown by deletions of the C-terminal 5 amino acids or alanine-scanning mutagenesis, but it is not required for binding of AIP to hsp90. The data support a model where 1) AIP binds to both hsp90 and AhR; 2) hsp90 is required for AhR-AIP binding; and 3) the binding of AhR to AIP stabilizes the AIP-hsp90-AhR complex. JF - The Journal of biological chemistry AU - Bell, D R AU - Poland, A AD - Centers for Disease Control, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Morgantown, West Virginia 26505, USA. david.bell@nottingham.ac.uk Y1 - 2000/11/17/ PY - 2000 DA - 2000 Nov 17 SP - 36407 EP - 36414 VL - 275 IS - 46 SN - 0021-9258, 0021-9258 KW - Benzoquinones KW - 0 KW - Cell Extracts KW - HSP90 Heat-Shock Proteins KW - Intracellular Signaling Peptides and Proteins KW - Lactams, Macrocyclic KW - Nucleotides KW - Proteins KW - Quinones KW - Receptors, Aryl Hydrocarbon KW - Recombinant Proteins KW - aryl hydrocarbon receptor-interacting protein KW - Lysine KW - K3Z4F929H6 KW - geldanamycin KW - Z3K3VJ16KU KW - Index Medicus KW - Animals KW - Transcription, Genetic KW - Quinones -- pharmacology KW - Lysine -- genetics KW - Lysine -- metabolism KW - Reticulocytes -- drug effects KW - Sequence Alignment KW - Recombinant Proteins -- metabolism KW - Molecular Sequence Data KW - Reticulocytes -- metabolism KW - Nucleotides -- pharmacology KW - Protein Biosynthesis KW - Temperature KW - Reticulocytes -- cytology KW - Mice KW - Amino Acid Sequence KW - Precipitin Tests KW - Binding Sites KW - Protein Binding -- drug effects KW - Protein Structure, Tertiary KW - Mutation KW - Proteins -- chemistry KW - HSP90 Heat-Shock Proteins -- metabolism KW - Receptors, Aryl Hydrocarbon -- metabolism KW - Proteins -- metabolism KW - Proteins -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72435983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+biological+chemistry&rft.atitle=Binding+of+aryl+hydrocarbon+receptor+%28AhR%29+to+AhR-interacting+protein.+The+role+of+hsp90.&rft.au=Bell%2C+D+R%3BPoland%2C+A&rft.aulast=Bell&rft.aufirst=D&rft.date=2000-11-17&rft.volume=275&rft.issue=46&rft.spage=36407&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+biological+chemistry&rft.issn=00219258&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-12-29 N1 - Date created - 2000-12-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - (13)C NMR and electron ionization mass spectrometric data-activity relationship model of estrogen receptor binding. AN - 72414795; 11076692 AB - Two Spectroscopic Data-Activity Relationship (SDAR) models based on (13)C nuclear magnetic resonance (NMR) and electron ionization mass spectra (EI MS) data were developed for 108 compounds whose relative binding affinities (RBA) to the estrogen receptor are known. The (13)C NMR and EI MS data were used as spectrometric digital fingerprints to reflect the electronic and structural characteristics of the compounds. Both SDAR models segregated the 108 compounds into 20 strong, 15 medium, and 73 weak relative binding classifications. The first SDAR model, based on (13)C NMR data alone, gave a leave-one-out (LOO) cross-validation of 75.0%. The second SDAR model, based on a composite of (13)C NMR and EI MS data, gave a LOO cross-validation of 82.4%. Many of the misidentifications from the cross-validations were between medium and weak classifications, where there were fewer specific spectrometric characteristics to identify the relationship of spectra to estrogen receptor binding. Real and predicted (13)C NMR chemical shifts were used to test the predictive behavior of both SDAR models. The ease of use and speed of SDAR modeling may facilitate their use with other toxicological endpoints. JF - Toxicology and applied pharmacology AU - Beger, R D AU - Freeman, J P AU - Lay, J O AU - Wilkes, J G AU - Miller, D W AD - Division of Chemistry, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arizona 72079, USA. rbeger@NCTR.FDA.GOV Y1 - 2000/11/15/ PY - 2000 DA - 2000 Nov 15 SP - 17 EP - 25 VL - 169 IS - 1 SN - 0041-008X, 0041-008X KW - Carbon Radioisotopes KW - 0 KW - Estrogens, Non-Steroidal KW - Receptors, Estrogen KW - Index Medicus KW - Discriminant Analysis KW - Estrogens, Non-Steroidal -- chemistry KW - Estrogens, Non-Steroidal -- metabolism KW - Magnetic Resonance Spectroscopy -- methods KW - Quantitative Structure-Activity Relationship KW - Models, Molecular KW - Receptors, Estrogen -- chemistry KW - Receptors, Estrogen -- metabolism KW - Spectrometry, Mass, Electrospray Ionization -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72414795?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=%2813%29C+NMR+and+electron+ionization+mass+spectrometric+data-activity+relationship+model+of+estrogen+receptor+binding.&rft.au=Beger%2C+R+D%3BFreeman%2C+J+P%3BLay%2C+J+O%3BWilkes%2C+J+G%3BMiller%2C+D+W&rft.aulast=Beger&rft.aufirst=R&rft.date=2000-11-15&rft.volume=169&rft.issue=1&rft.spage=17&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=0041008X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-04 N1 - Date created - 2000-12-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - C NMR and Electron Ionization Mass Spectrometric Data-Activity Relationship Model of Estrogen Receptor Binding AN - 17724315; 4795943 AB - Two Spectroscopic Data-Activity Relationship (SDAR) models based on super(13)C nuclear magnetic resonance (NMR) and electron ionization mass spectra (EI MS) data were developed for 108 compounds whose relative binding affinities (RBA) to the estrogen receptor are known. The super(13)C NMR and EI MS data were used as spectrometric digital fingerprints to reflect the electronic and structural characteristics of the compounds. Both SDAR models segregated the 108 compounds into 20 strong, 15 medium, and 73 weak relative binding classifications. The first SDAR model, based on super(13)C NMR data alone, gave a leave-one-out (LOO) cross-validation of 75.0%. The second SDAR model, based on a composite of super(13)C NMR and EI MS data, gave a LOO cross-validation of 82.4%. Many of the misidentifications from the cross-validations were between medium and weak classifications, where there were fewer specific spectrometric characteristics to identify the relationship of spectra to estrogen receptor binding. Real and predicted super(13)C NMR chemical shifts were used to test the predictive behavior of both SDAR models. The ease of use and speed of SDAR modeling may facilitate their use with other toxicological endpoints. JF - Toxicology and Applied Pharmacology AU - Beger, R D AU - Freeman, J P AU - Lay, JO Jr AU - Wilkes, J G AU - Miller, D W AD - Division of Chemistry, National Center for Toxicological Research, Food and Drug Administration, Jefferson, 72079, Arizona, rbeger@NCTR.FDA.GOV Y1 - 2000/11/15/ PY - 2000 DA - 2000 Nov 15 SP - 17 EP - 25 PB - Academic Press VL - 169 IS - 1 SN - 0041-008X, 0041-008X KW - Toxicology Abstracts KW - N.M.R. KW - Xenobiotics KW - Estrogen receptors KW - Models KW - X 24222:Analytical procedures UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17724315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=C+NMR+and+Electron+Ionization+Mass+Spectrometric+Data-Activity+Relationship+Model+of+Estrogen+Receptor+Binding&rft.au=Beger%2C+R+D%3BFreeman%2C+J+P%3BLay%2C+JO+Jr%3BWilkes%2C+J+G%3BMiller%2C+D+W&rft.aulast=Beger&rft.aufirst=R&rft.date=2000-11-15&rft.volume=169&rft.issue=1&rft.spage=17&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1006%2Ftaap.2000.9043 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - N.M.R.; Xenobiotics; Models; Estrogen receptors DO - http://dx.doi.org/10.1006/taap.2000.9043 ER - TY - CONF T1 - Characterization of tumor vaccines during product development AN - 17859023; 5104553 AB - The term tumor vaccines encompasses a wide variety of diverse agents capable of interacting with the immune system to produce local inflammation, delayed type hypersensitivity reaction and/or tumor regression and, hopefully, a therapeutic effect. These vaccines may be grouped into the following general areas: (1) Cell-based vaccines such as manipulated tumor cells, activated peripheral blood or bone marrow-derived lymphocytes, dendritic cells or other antigen presenting cells (APC) and gene-modified tumor cells or other cells engineered to express cytokines, growth factors or tumor antigens. (2) Antigen preparations, such as synthetic peptides, purified antigens and tumor cell lysates. (3) Viral and plasmid vectors expressing therapeutic genes. (4) Liposome containing antigen, peptides, plasmids encoding tumor antigens. While no tumor vaccine has been licensed by the FDA, numerous clinical trials are ongoing and some products have advanced to Phase III pivotal stages of development. However, as with many novel products, major regulatory and scientific issues associated with clinical use of tumor vaccines remain to be addressed. In this paper, we address issues associated with different types of tumor vaccines and provide recommendations for the characterization of these vaccines at various stages of development. JF - Vaccine AU - Razzaque, A AU - Dye, E AU - Puri, R K Y1 - 2000/11/08/ PY - 2000 DA - 2000 Nov 08 SP - 644 EP - 647 PB - Butterworth-Heinemann, 313 Washington St. Newton MA 02158 USA VL - 19 IS - 6 KW - Biotechnology and Bioengineering Abstracts; Medical and Pharmaceutical Biotechnology Abstracts; Immunology Abstracts KW - Immunotherapy KW - Tumors KW - Reviews KW - Antigen (tumor-associated) KW - Cytokines KW - Growth factors KW - Antigen-presenting cells KW - Vaccines KW - F 06818:Cancer immunotherapy KW - W3 33350:Cancer vaccines KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17859023?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Characterization+of+tumor+vaccines+during+product+development&rft.au=Razzaque%2C+A%3BDye%2C+E%3BPuri%2C+R+K&rft.aulast=Razzaque&rft.aufirst=A&rft.date=2000-11-08&rft.volume=19&rft.issue=6&rft.spage=644&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Genetic and immunologic characterization of a novel serotype 4, 15 strain of Neisseria meningitidis AN - 17692116; 4781749 AB - The porin proteins of Neisseria meningitidis are important components of outer membrane protein (OMP) vaccines. The class 3 porin gene, porB, of a novel serogroup B, serotype 4, 15 isolate from Chile (Ch501) was found to be VR1-4, VR2-15, VR3-15 and VR4-15 by porB variable region (VR) typing. Rabbit immunization studies using outer membrane vesicles revealed immunodominance of individual PorB (class 3) VR epitopes. The predominant anti-Ch501 PorB response was directed to the VR1 epitope. Anti-PorB VR1 mediated killing was suggested by the bactericidal activity of Ch501 anti-sera against a type 4 strain not expressing PorA or class 5 OMPs. Studies that examine the molecular epidemiology of individual porB VRs, and the immune responses to PorB epitopes, may contribute to the development of broadly protective group B meningococcal vaccines. JF - FEMS Immunology and Medical Microbiology AU - Bash, M C AU - Lynn, F AU - Concepcion, N F AU - Tappero, J W AU - Carlone, G M AU - Frasch, CE AD - Division of Bacterial, Allergenic and Parasitic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA, bash@cber.fda.gov Y1 - 2000/11/04/ PY - 2000 DA - 2000 Nov 04 SP - 169 EP - 176 PB - Elsevier VL - 29 IS - 3 SN - 0928-8244, 0928-8244 KW - isolates KW - Chile KW - porB gene KW - Microbiology Abstracts B: Bacteriology KW - Typing KW - Genotyping KW - Immune response KW - Neisseria meningitidis KW - Meningitis KW - J 02833:Immune response and immune mechanisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17692116?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Immunology+and+Medical+Microbiology&rft.atitle=Genetic+and+immunologic+characterization+of+a+novel+serotype+4%2C+15+strain+of+Neisseria+meningitidis&rft.au=Bash%2C+M+C%3BLynn%2C+F%3BConcepcion%2C+N+F%3BTappero%2C+J+W%3BCarlone%2C+G+M%3BFrasch%2C+CE&rft.aulast=Bash&rft.aufirst=M&rft.date=2000-11-04&rft.volume=29&rft.issue=3&rft.spage=169&rft.isbn=&rft.btitle=&rft.title=FEMS+Immunology+and+Medical+Microbiology&rft.issn=09288244&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Neisseria meningitidis; Immune response; Meningitis; Typing; Genotyping ER - TY - JOUR T1 - Fewer symptoms occur in same-serotype recurrent streptococcal tonsillopharyngitis. AN - 85356554; pmid-11074833 AB - BACKGROUND: Most patients with acute rheumatic fever report no antecedent pharyngitis. OBJECTIVE: To determine the clinical and microbiological characteristics of recurrent group A beta-hemolytic streptococcal (GABHS) tonsillopharyngitis. DESIGN: Prospective randomized trial. SUBJECTS: Symptoms were recorded and throat cultures were obtained at 4 to 6, 18 to 21, and 32 to 35 days following the start of treatment. A subset of 60 patients with subsequent GABHS episodes occurring were evaluated for a 0.2-or greater log rise in either antistreptolysin O or anti-deoxyribonuclease B titer to confirm a bona fide recurrence. RESULTS: Sixteen (27%) of 60 patients had recurrent GABHS tonsillopharyngitis of the same serotype that occurred 21 days or longer following the onset of the initial GABHS infection and was associated with a 0.2- or greater log rise in either antistreptolysin O or anti-deoxyribonuclease B titer, indicating bona fide recurrent infection; these recurrences all occurred within 55 days. Fewer patients with recurrent GABHS pharyngitis of the same serotype had headache (P =.02), sore throat (P =.006), fever (P =. 008), pharyngeal erythema (P<.001), pharyngeal edema (P<.001), pharyngeal exudate (P =.04), and adenitis (P =.03) compared with the initial episode. Chills, stomachache, scarlatina, tonsillar enlargement, and palatal petechiae were similar for both episodes. CONCLUSIONS: Fewer symptoms occur during recurrent GABHS pharyngitis of the same serotype compared with the initial infection. These patients may be less likely to seek physician attention, yet their infections put them at risk for sequelae. JF - Archives of otolaryngology--head & neck surgery AU - Lee, L H AU - Ayoub, E AU - Pichichero, M E AD - Food and Drug Administration, Division of Vaccines and Related Product Applications, HFM 475, Suite 370N, 1401 Rockville Pike, Rockville, MD 20852, USA. Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 1359 EP - 1362 VL - 126 IS - 11 SN - 0886-4470, 0886-4470 KW - National Library of Medicine KW - Severity of Illness Index KW - Prospective Studies KW - Humans KW - Serotyping KW - Child KW - Adolescent KW - Recurrence KW - Child, Preschool KW - Streptococcus pyogenes -- classification KW - Streptococcus agalactiae -- classification KW - Tonsillitis -- microbiology KW - Pharyngitis -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85356554?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+otolaryngology--head+%26+neck+surgery&rft.atitle=Fewer+symptoms+occur+in+same-serotype+recurrent+streptococcal+tonsillopharyngitis.&rft.au=Lee%2C+L+H%3BAyoub%2C+E%3BPichichero%2C+M+E&rft.aulast=Lee&rft.aufirst=L&rft.date=2000-11-01&rft.volume=126&rft.issue=11&rft.spage=1359&rft.isbn=&rft.btitle=&rft.title=Archives+of+otolaryngology--head+%26+neck+surgery&rft.issn=08864470&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-12 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Effect of silica inhalation on the pulmonary clearance of a bacterial pathogen in Fischer 344 rats. AN - 72606025; 11361057 AB - Silica inhalation predisposes workers to bacterial infection and impairments in pulmonary defense function. In this study, we evaluated the effect of pre-exposure to silica on lung defense mechanisms by use of a rat pulmonary Listeria monocytogenes infection model. Male Fischer 344 rats were exposed by inhalation to filtered air or silica (15 mg/m3 x 6 h/day x 5 days/wk). After 21 or 59 days of silica exposure, the rats were inoculated intratracheally with 5 x 10(3) L. monocytogenes. At 0 (noninfected controls), 3, and 7 days after infection, the left lungs were removed, homogenized, and the number of viable L. monocytogenes was counted after an overnight culture at 37 degrees C. Bronchoalveolar lavage (BAL) was performed on the right lungs. Alveolar macrophages (AM) were collected, and the AM production of chemiluminescence (CL), an index of reactive oxygen species generation, was measured. The number of lavagable neutrophils (PMNs) and acellular BAL lactate dehydrogenase (LDH) activity were determined as indices of inflammation and injury, respectively. Pre-exposure to silica for 59 days caused substantial increases in PMN number and LDH activity compared with the air controls, whereas silica inhalation for both 21 and 59 days significantly enhanced the pulmonary clearance of L. monocytogenes compared with air controls. Dramatic elevations were also observed in zymosan- and phorbol myristate acetate (PMA)-stimulated CL production by lung phagocytes recovered from rats pre-exposed to silica for 59 days. These results demonstrate that short-term exposure to inhaled silica particles activates lung phagocytes, as evidenced by increases in reactive oxygen species. This up-regulation in the production of antimicrobial oxidants is likely responsible for the enhancement in pulmonary clearance of L. monocytogenes observed with short-term silica inhalation. JF - Lung AU - Antonini, J M AU - Roberts, J R AU - Yang, H M AU - Barger, M W AU - Ramsey, D AU - Castranova, V AU - Ma, J Y AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA. PY - 2000 SP - 341 EP - 350 VL - 178 IS - 6 SN - 0341-2040, 0341-2040 KW - Reactive Oxygen Species KW - 0 KW - Silicon Dioxide KW - 7631-86-9 KW - L-Lactate Dehydrogenase KW - EC 1.1.1.27 KW - Index Medicus KW - Reactive Oxygen Species -- metabolism KW - Animals KW - Analysis of Variance KW - Bronchoalveolar Lavage KW - Macrophages, Alveolar -- metabolism KW - Neutrophils -- metabolism KW - Rats KW - Rats, Inbred F344 KW - Luminescent Measurements KW - Colony Count, Microbial KW - Up-Regulation KW - Administration, Inhalation KW - L-Lactate Dehydrogenase -- metabolism KW - Male KW - Silicon Dioxide -- administration & dosage KW - Pneumonia, Bacterial -- microbiology KW - Listeriosis -- immunology KW - Pneumonia, Bacterial -- immunology KW - Pneumonia, Bacterial -- metabolism KW - Silicon Dioxide -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72606025?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lung&rft.atitle=Effect+of+silica+inhalation+on+the+pulmonary+clearance+of+a+bacterial+pathogen+in+Fischer+344+rats.&rft.au=Antonini%2C+J+M%3BRoberts%2C+J+R%3BYang%2C+H+M%3BBarger%2C+M+W%3BRamsey%2C+D%3BCastranova%2C+V%3BMa%2C+J+Y&rft.aulast=Antonini&rft.aufirst=J&rft.date=2000-11-01&rft.volume=178&rft.issue=6&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=Lung&rft.issn=03412040&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-06-14 N1 - Date created - 2001-05-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Suggestion of a cause-and-effect relationship among coal rank, airborne dust, and incidence of workers' pneumoconiosis. AN - 72518644; 11192209 JF - AIHAJ : a journal for the science of occupational and environmental health and safety AU - Page, S J AU - Organiscak, J A AD - Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Pittsburgh Research Laboratory, PA 15236, USA. sep8@cdc.gov PY - 2000 SP - 785 EP - 787 VL - 61 IS - 6 SN - 1529-8663, 1529-8663 KW - Air Pollutants, Occupational KW - 0 KW - Coal KW - Dust KW - Index Medicus KW - Humans KW - Incidence KW - United States -- epidemiology KW - Coal -- adverse effects KW - Pneumoconiosis -- etiology KW - Pneumoconiosis -- epidemiology KW - Air Pollutants, Occupational -- adverse effects KW - Coal Mining KW - Dust -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72518644?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIHAJ+%3A+a+journal+for+the+science+of+occupational+and+environmental+health+and+safety&rft.atitle=Suggestion+of+a+cause-and-effect+relationship+among+coal+rank%2C+airborne+dust%2C+and+incidence+of+workers%27+pneumoconiosis.&rft.au=Page%2C+S+J%3BOrganiscak%2C+J+A&rft.aulast=Page&rft.aufirst=S&rft.date=2000-11-01&rft.volume=61&rft.issue=6&rft.spage=785&rft.isbn=&rft.btitle=&rft.title=AIHAJ+%3A+a+journal+for+the+science+of+occupational+and+environmental+health+and+safety&rft.issn=15298663&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-03-22 N1 - Date created - 2001-01-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A quantitative study of aromatic amine permeation through protective gloves using amine adsorptive pads. AN - 72518069; 11192217 AB - A quantitative study of aromatic amine permeation through a glove material using Permea-Tec aromatic amine pads, used for the detection of chemical breakthrough of protective clothing, was performed for aniline following the microwave extraction process and gas chromatographic analysis. Aniline exhibited >99% adsorption on the pads at a spiking level of 1.94 mg (1.9 microL). Aniline showed recoveries from 65 to 89% (RSD < or =5.6%) over the range 1.1-1.9 microL (1.12-1.94 mg) of aniline applied to pads. The modified ASTM F739 and direct permeability testing procedures were used to determine breakthrough times for five protective glove materials using aniline as a challenge chemical. Breakthrough times for six protective gloves were determined, ranging from 182 sec to 82 min. The quantitative concentration of aniline on the pads following permeation through the gloves also was determined, ranging from 0.53 to 0.55 mg/cm2 (1.79-1.88 mg/pad). JF - AIHAJ : a journal for the science of occupational and environmental health and safety AU - Vo, E AU - Berardinelli, S P AU - Hall, R C AU - El Ayouby, N AD - National Institute for Occupational Safety and Health, Division of Safety Research, Morgantown, WV 26505, USA. PY - 2000 SP - 837 EP - 841 VL - 61 IS - 6 SN - 1529-8663, 1529-8663 KW - Aniline Compounds KW - 0 KW - aniline KW - SIR7XX2F1K KW - Index Medicus KW - United States KW - Equipment Design KW - Chromatography, Gas KW - Humans KW - Adsorption KW - Calibration KW - Permeability KW - Gloves, Protective -- standards KW - Materials Testing -- methods KW - Aniline Compounds -- analysis KW - Occupational Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72518069?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+...+North+American+Rock+Mechanics+Symposium&rft.atitle=Experimental+study+on+the+stability+of+dam+foundation+in+consideration+of+the+effect+of+the+concrete+plug+treatments&rft.au=Nakashima%2C+S%3BKishida%2C+K%3BAdachi%2C+T%3BIzu%2C+Y&rft.aulast=Nakashima&rft.aufirst=S&rft.date=2000-01-01&rft.volume=4&rft.issue=&rft.spage=1225&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+...+North+American+Rock+Mechanics+Symposium&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-03-22 N1 - Date created - 2001-01-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Producing 13C NMR, infrared absorption, and electron ionization mass spectrometric data models of the monodechlorination of chlorobenzenes, chlorophenols, and chloroanilines. AN - 72513668; 11128104 AB - We have developed four spectroscopic data-activity relationship (SDAR) models of monodechlorination of 32 chlorinated benzene compounds in anaerobic estuarine sediment. The SDAR models were based on combinations of 13C nuclear magnetic resonance (NMR), infrared absorption (IR), and electron ionization mass spectrometric (EI MS) data. The SDAR models segregated the 32 compounds into 17 readily monodechlorinated compounds and 15 not readily monodechlorinated compounds. The SDAR model based on 13C NMR, IR, and EI MS data gave a leave-one-out cross-validation of 93.8%. The SDAR model based on a composite of 13C NMR and IR data gave a leave-one-out cross-validation of 90.6%. The SDAR model based on a composite of IR and EI MS data gave a leave-one-out cross-validation of 84.4%. The SDAR model based on a composite of 13C NMR and EI MS data gave a leave-one-out cross-validation of 84.4%. These reliable SDAR models provide a rapid and simple way to predict whether a chlorinated benzene compound will readily go through monodechlorination. The FDA has filed a patent application on methods of using any combination of spectral data (NMR, MS, UV-vis, IR, and fluorescence, phosphorescence) to model a chemical, physical, or biological endpoint. JF - Journal of chemical information and computer sciences AU - Beger, R D AU - Freeman, J P AU - Lay, J O AU - Wilkes, J G AU - Miller, D W AD - Division of Chemistry, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA. rbeger@NCTR.FDA.GOV PY - 2000 SP - 1449 EP - 1455 VL - 40 IS - 6 SN - 0095-2338, 0095-2338 KW - Carbon Isotopes KW - 0 KW - Hydrocarbons, Chlorinated KW - Water Pollutants, Chemical KW - Index Medicus KW - Spectrophotometry, Infrared KW - Models, Chemical KW - Mass Spectrometry -- methods KW - Hydrocarbons, Chlorinated -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72513668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chemical+information+and+computer+sciences&rft.atitle=Producing+13C+NMR%2C+infrared+absorption%2C+and+electron+ionization+mass+spectrometric+data+models+of+the+monodechlorination+of+chlorobenzenes%2C+chlorophenols%2C+and+chloroanilines.&rft.au=Beger%2C+R+D%3BFreeman%2C+J+P%3BLay%2C+J+O%3BWilkes%2C+J+G%3BMiller%2C+D+W&rft.aulast=Beger&rft.aufirst=R&rft.date=2000-11-01&rft.volume=40&rft.issue=6&rft.spage=1449&rft.isbn=&rft.btitle=&rft.title=Journal+of+chemical+information+and+computer+sciences&rft.issn=00952338&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-01 N1 - Date created - 2000-12-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Evaluating presence/absence of target microbes in microbiological tests. AN - 72502959; 11128148 AB - A typical qualitative microbiological method performance (collaborative) study gathers a data set of responses about a test for the presence or absence of a target microbe. We developed 2 models that estimate false-positive and false-negative rates. One model assumes a constant probability that the tests will indicate the target microbe is present for any positive concentration in the test portion. The other model assumes that this probability follows a logistic curve. Test results from several method performance studies illustrate these estimates. JF - Journal of AOAC International AU - Blodgett, R J AU - Hitchins, A D AD - U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Washington, DC 20204, USA. PY - 2000 SP - 1429 EP - 1433 VL - 83 IS - 6 SN - 1060-3271, 1060-3271 KW - Index Medicus KW - Dairy Products -- microbiology KW - Logistic Models KW - Algorithms KW - Models, Statistical KW - Meat -- microbiology KW - Food Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72502959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+AOAC+International&rft.atitle=Evaluating+presence%2Fabsence+of+target+microbes+in+microbiological+tests.&rft.au=Blodgett%2C+R+J%3BHitchins%2C+A+D&rft.aulast=Blodgett&rft.aufirst=R&rft.date=2000-11-01&rft.volume=83&rft.issue=6&rft.spage=1429&rft.isbn=&rft.btitle=&rft.title=Journal+of+AOAC+International&rft.issn=10603271&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-03-01 N1 - Date created - 2000-12-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Handling adverse event reports. AN - 72477129; 11111664 JF - Nursing AU - Rich, S AD - Center for Devices and Radiological Health, Food and Drug Administration, Rockville, Md., USA. Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 78 VL - 30 IS - 11 SN - 0360-4039, 0360-4039 KW - Nursing KW - United States KW - United States Food and Drug Administration KW - Humans KW - Equipment Failure KW - Equipment Safety KW - Databases, Factual KW - Adverse Drug Reaction Reporting Systems -- organization & administration UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72477129?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nursing&rft.atitle=Handling+adverse+event+reports.&rft.au=Rich%2C+S&rft.aulast=Rich&rft.aufirst=S&rft.date=2000-11-01&rft.volume=30&rft.issue=11&rft.spage=78&rft.isbn=&rft.btitle=&rft.title=Nursing&rft.issn=03604039&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-12-18 N1 - Date created - 2000-12-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Progress report on the guidance for industry for statistical aspects of the design, analysis, and interpretation of chronic rodent carcinogenicity studies of pharmaceuticals. AN - 72439793; 11104389 AB - The U.S. Food and Drug Administration (FDA) is in the process of preparing a draft Guidance for Industry document on the statistical aspects of carcinogenicity studies of pharmaceuticals for public comment. The purpose of the document is to provide statistical guidance for the design of carcinogenicity experiments, methods of statistical analysis of study data, interpretation of study results, presentation of data and results in reports, and submission of electronic study data. This article covers the genesis of the guidance document and some statistical methods in study design, data analysis, and interpretation of results included in the draft FDA guidance document. JF - Journal of biopharmaceutical statistics AU - Lin, K K AD - Division of Biometrics 2, Office of Biostatistics, Center for Drug Evaluation and Research, US Food and Drug Administration, Rockville, Maryland 20857, USA. Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 481 EP - 501 VL - 10 IS - 4 SN - 1054-3406, 1054-3406 KW - Index Medicus KW - United States KW - Animals KW - United States Food and Drug Administration KW - Reproducibility of Results KW - Humans KW - Guidelines as Topic KW - Rodentia KW - Research Design -- statistics & numerical data KW - Drug-Related Side Effects and Adverse Reactions KW - Data Interpretation, Statistical KW - Drug Industry -- statistics & numerical data KW - Carcinogenicity Tests -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72439793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+biopharmaceutical+statistics&rft.atitle=Progress+report+on+the+guidance+for+industry+for+statistical+aspects+of+the+design%2C+analysis%2C+and+interpretation+of+chronic+rodent+carcinogenicity+studies+of+pharmaceuticals.&rft.au=Lin%2C+K+K&rft.aulast=Lin&rft.aufirst=K&rft.date=2000-11-01&rft.volume=10&rft.issue=4&rft.spage=481&rft.isbn=&rft.btitle=&rft.title=Journal+of+biopharmaceutical+statistics&rft.issn=10543406&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-05-31 N1 - Date created - 2001-03-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Current status of food animal antidotes. AN - 72425400; 11084985 AB - The availability of antidotes in veterinary medicine has been an issue for more than a decade. Antidotes are available for food animals through extralabel use, regulatory discretion, and compounding. There is little economic incentive for pharmaceutical companies to pursue approval of antidotes and other drug products that have a small market. In addition, human food safety concerns must be addressed when approving antidotes for use in food animals. This article provides a brief history of antidote availability, current mechanisms for procuring food animal antidotes, and availability of specific antidotes for use in food animals. JF - The Veterinary clinics of North America. Food animal practice AU - Post, L O AU - Keller, W C AD - Division of Surveillance, Food and Drug Administration, Rockville, Maryland, USA. Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 445 EP - 53, vi VL - 16 IS - 3 SN - 0749-0720, 0749-0720 KW - Antidotes KW - 0 KW - Index Medicus KW - United States KW - Animals, Domestic KW - Food Contamination -- prevention & control KW - Animals KW - Humans KW - Animal Husbandry KW - Drug Approval KW - Antidotes -- supply & distribution KW - Antidotes -- therapeutic use KW - Veterinary Medicine KW - United States Food and Drug Administration -- legislation & jurisprudence KW - Consumer Product Safety -- legislation & jurisprudence UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72425400?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Veterinary+clinics+of+North+America.+Food+animal+practice&rft.atitle=Current+status+of+food+animal+antidotes.&rft.au=Post%2C+L+O%3BKeller%2C+W+C&rft.aulast=Post&rft.aufirst=L&rft.date=2000-11-01&rft.volume=16&rft.issue=3&rft.spage=445&rft.isbn=&rft.btitle=&rft.title=The+Veterinary+clinics+of+North+America.+Food+animal+practice&rft.issn=07490720&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-04 N1 - Date created - 2000-11-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Exposure potentials during cleaning, overhauling and repairing of aircraft lavatory tanks and hardware. AN - 72389951; 11062923 JF - Applied occupational and environmental hygiene AU - Burton, N C AU - McCleery, R E AD - Hazard Evaluation and Technical Assistance Branch of NIOSH, Cincinnati, Ohio 45226, USA. Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 803 EP - 808 VL - 15 IS - 11 SN - 1047-322X, 1047-322X KW - Index Medicus KW - Bacterial Infections KW - Ventilation KW - Humans KW - Hygiene KW - Disease Transmission, Infectious KW - Occupational Exposure KW - Toilet Facilities KW - Aircraft UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72389951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+occupational+and+environmental+hygiene&rft.atitle=Exposure+potentials+during+cleaning%2C+overhauling+and+repairing+of+aircraft+lavatory+tanks+and+hardware.&rft.au=Burton%2C+N+C%3BMcCleery%2C+R+E&rft.aulast=Burton&rft.aufirst=N&rft.date=2000-11-01&rft.volume=15&rft.issue=11&rft.spage=803&rft.isbn=&rft.btitle=&rft.title=Applied+occupational+and+environmental+hygiene&rft.issn=1047322X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-12-05 N1 - Date created - 2000-12-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Induction of micronuclei following exposure to methylene di-phenyl diisocyanate: potential genotoxic metabolites. AN - 72376228; 11053546 AB - Methylene di-phenyl diisocyanate (MDI) is used to make polyurethane products. The predominant occupational disease attributed to diisocyanates, including MDI, is asthma; however, the potential for genotoxicity has also been of concern. Diisocyanates are very reactive compounds that can undergo nonenzymatic hydrolysis to form methylenedianiline (MDA), or react under physiological conditions with primary amines to form ureas and/or with thiols to form labile thiol acid esters. MDA is a carcinogen in animals and a suspected carcinogen in humans. Brown Norway rats (BNR) were exposed to either 7 or 113 mg/m(3) MDI aerosol for 1 h/week x3 weeks and sacrificed 1 week later. Micronuclei (MN) formation was assessed from bone marrow polychromatic erythrocytes (PCE). A dose-dependent increase in the frequency of micronucleated polychromatic erythrocytes (MN-PCEs) was noted. In vitro exposure of Chinese hamster lung fibroblasts (V79) to MDA or MDI-thiol conjugates, but not to MDI, significantly increased the frequency of MN. MDI-thiol conjugate-exposed cell cultures did not have detectable levels of MDA. A significant increase in the number of V79 cells in metaphase, as well as the number of cells with precipitants within both the cytoplasm and nuclei, were noted in MDI-glutathione-exposed cultures. The results of this study indicate that MDI aerosol exposure can cause MN formation through either the hydrolysis of MDI to MDA or possibly the formation of thiol conjugates. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Zhong, B Z AU - Siegel, P D AD - Health Effect Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505-2888, USA. Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 102 EP - 108 VL - 58 IS - 1 SN - 1096-6080, 1096-6080 KW - Aerosols KW - 0 KW - Aniline Compounds KW - Carcinogens KW - Isocyanates KW - Mutagens KW - 4,4'-diphenylmethane diisocyanate KW - 101-68-8 KW - Glutathione KW - GAN16C9B8O KW - 4,4'-diaminodiphenylmethane KW - GG5LL7OBZC KW - Cysteine KW - K848JZ4886 KW - Index Medicus KW - Bone Marrow Cells -- drug effects KW - Animals KW - Fibroblasts -- drug effects KW - Cysteine -- metabolism KW - Dose-Response Relationship, Drug KW - Microsomes, Liver -- metabolism KW - Glutathione -- metabolism KW - Aniline Compounds -- toxicity KW - Rats, Inbred Strains KW - Rats KW - Rats, Sprague-Dawley KW - Inhalation Exposure KW - Microsomes, Liver -- drug effects KW - Bone Marrow Cells -- cytology KW - Cell Line KW - Cricetinae KW - Erythrocytes -- drug effects KW - Isocyanates -- administration & dosage KW - Micronucleus Tests KW - Isocyanates -- toxicity KW - Carcinogens -- metabolism KW - Carcinogens -- administration & dosage KW - Isocyanates -- metabolism KW - Mutagens -- metabolism KW - Erythrocytes -- cytology KW - Carcinogens -- toxicity KW - Mutagens -- toxicity KW - Mutagens -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72376228?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Induction+of+micronuclei+following+exposure+to+methylene+di-phenyl+diisocyanate%3A+potential+genotoxic+metabolites.&rft.au=Zhong%2C+B+Z%3BSiegel%2C+P+D&rft.aulast=Zhong&rft.aufirst=B&rft.date=2000-11-01&rft.volume=58&rft.issue=1&rft.spage=102&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-30 N1 - Date created - 2000-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Latex allergy in the workplace. AN - 72375695; 11053535 AB - While less than 1% of the general population is sensitized to latex, the U.S. Occupational Safety and Health Administration estimates that 8-12% of health-care workers are sensitized. The major source of workplace exposure is powdered natural rubber latex (NRL) gloves. NRL is harvested from HEVEA: brasiliensis trees and ammoniated to prevent coagulation resulting in the hydrolysis of the latex proteins. Prior to use in manufacturing, the latex is formulated by the addition of multiple chemicals. Thus, human exposure is to a mixture of residual chemicals and hydrolyzed latex peptides. Clinical manifestations include irritant contact dermatitis, allergic contact dermatitis (type IV), and type I immediate hypersensitivity response. Type I (IgE-mediated) NRL allergy includes contact urticaria, systemic urticaria, angioedema, rhinitis, conjunctivitis, bronchospasm, and anaphylaxis. Taking an accurate history, including questions on atopic status, food allergy, and possible reactions to latex devices makes diagnosis of type-I latex allergy possible. To confirm a diagnosis, either in vivo skin prick testing (SPT) or in vitro assays for latex-specific IgE are performed. While the SPT is regarded as a primary confirmatory test for IgE-mediated disease, the absence of a U.S. Food and Drug Administration-licensed HEVEA: brasiliensis latex extract has restricted its use in diagnosis. Serological tests have, therefore, become critically important as alternative diagnostic tests. Three manufacturers currently have FDA clearance for in vitro tests, to detect NRL-specific IgE. The commercially available assays may disagree on the antibody status of an individual serum, which may be due to the assay's detecting anti-NRL IgEs to different allergenic NRL proteins. Sensitized individuals produce specific IgE antibody to at least 10 potent HEVEA: allergens, Hev b 1-Hev b 10, each of which differs in its structure, size, and net charge. The relative content and ratios of Hevs in the final allergen preparation most probably could effect diagnostic accuracy. The Hev proteins have been cloned and expressed as recombinant proteins. Sequencing demonstrates both unique epitopes and sequences commonly found in other plant proteins. Sequence homology helps to explain the cross reactivity to a variety of foods experienced by latex allergic individuals. The development of recombinant allergens provides reagents that should improve the diagnostic accuracy of tests for latex allergy. Although clinical and exposure data have been gathered on the factors affecting response in latex-allergic individuals, less is known regarding the development of sensitization. Coupled with in vitro dermal penetration studies, murine models have been established to investigate the route of exposure in the development of latex sensitization. Time-course and dose-response studies have shown subcutaneous, intratracheal, or topical administrations of non-ammoniated latex proteins to induce IgE production. Both in vitro penetration and in vivo studies highlight the importance of skin condition in the development of latex allergy, with enhanced penetration and earlier onset of IgE production seen with experimentally abraded skin. The diagnosis of latex allergy is complicated by these variables, which in turn hinder the development of intervention strategies. Further epidemiological assessment is needed to more explicitly define the scope, trends, and demographics of latex allergy. Diagnostic accuracy can be improved through greater knowledge of proteins involved in the development of latex allergy, and better documentation of the presently available diagnostic tests. In vivo and in vitro models can elucidate mechanisms of sensitization and provide an understanding of the role of the exposure route in latex allergy-associated diseases. Together, these efforts can lead to intervention strategies for reducing latex allergy in the workplace. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Toraason, M AU - Sussman, G AU - Biagini, R AU - Meade, J AU - Beezhold, D AU - Germolec, D AD - National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. mtorasson@cdc.gov Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 5 EP - 14 VL - 58 IS - 1 SN - 1096-6080, 1096-6080 KW - Reagent Kits, Diagnostic KW - 0 KW - Index Medicus KW - Humans KW - Health Personnel KW - Disease Models, Animal KW - Prevalence KW - Latex Hypersensitivity -- etiology KW - Latex Hypersensitivity -- epidemiology KW - Latex Hypersensitivity -- prevention & control KW - Dermatitis, Allergic Contact -- epidemiology KW - Dermatitis, Occupational -- etiology KW - Dermatitis, Allergic Contact -- prevention & control KW - Dermatitis, Allergic Contact -- etiology KW - Dermatitis, Occupational -- prevention & control KW - Occupational Exposure -- adverse effects KW - Dermatitis, Occupational -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72375695?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Latex+allergy+in+the+workplace.&rft.au=Toraason%2C+M%3BSussman%2C+G%3BBiagini%2C+R%3BMeade%2C+J%3BBeezhold%2C+D%3BGermolec%2C+D&rft.aulast=Toraason&rft.aufirst=M&rft.date=2000-11-01&rft.volume=58&rft.issue=1&rft.spage=5&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-30 N1 - Date created - 2000-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Subchronic silica exposure enhances respiratory defense mechanisms and the pulmonary clearance of Listeria monocytogenes in rats. AN - 72308387; 11015141 AB - Both Listeria monocytogenes infection and silica exposure have been shown to significantly alter immune responses. In this study, we evaluated the effect of preexposure to silica on lung defense mechanisms using a rat pulmonary L. monocytogenes infection model. Male Sprague-Dawley rats were instilled intratracheally with saline (vehicle control) or silica using either an acute treatment regimen (5 mg/kg; 3 days) or a subchronic treatment protocol (80 mg/kg; 35 days). At 3 or 35 days after silica instillation, the rats were inoculated intratracheally with either approximately 5000 or 500,000 L. monocytogenes. At 3, 5, and 7 days postinfection, the left lung was removed, homogenized, and cultured on brain heart infusion agar at 37 degrees C. The numbers of viable L. monocytogenes were counted after an overnight incubation. Bronchoalveolar lavage (BAL) was performed on the right lungs, and BAL cell differentials, acellular lactate dehydrogenase (LDH) activity and albumin content were determined. Alveolar macrophage (AM) chemiluminescence (CL) and phagocytosis were assessed as a measure of macrophage function. Lung-associated lymph nodes were removed, and lymphocytes were recovered and differentiated. Preexposure to silica significantly increased the pulmonary clearance of L. monocytogenes as compared to saline controls. Exposure to silica caused significant increases in BAL neutrophils, LDH and albumin, and lymph-nodal T cells and natural killer (NK) cells in infected and noninfected rats. CL and phagocytosis were also elevated in silica-treated rats. In summary, the results demonstrated that exposure of rats to silica enhanced pulmonary immune responses, as evidenced by increases in neutrophils, NK cells, T lymphocytes, and macrophage activation. These elevations in pulmonary immune response are likely responsible for the increase in pulmonary clearance of L. monocytogenes observed with preexposure to silica. JF - Inhalation toxicology AU - Antonini, J M AU - Yang, H M AU - Ma, J Y AU - Roberts, J R AU - Barger, M W AU - Butterworth, L AU - Charron, T G AU - Castranova, V AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA. jga6@cdc.gov Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 1017 EP - 1036 VL - 12 IS - 11 SN - 0895-8378, 0895-8378 KW - Silicon Dioxide KW - 7631-86-9 KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Macrophages -- physiology KW - Cell Differentiation KW - Neutrophils -- physiology KW - Lymphocytes -- physiology KW - Male KW - Lung -- immunology KW - Silicon Dioxide -- adverse effects KW - Lung -- microbiology KW - Listeria monocytogenes -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72308387?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inhalation+toxicology&rft.atitle=Subchronic+silica+exposure+enhances+respiratory+defense+mechanisms+and+the+pulmonary+clearance+of+Listeria+monocytogenes+in+rats.&rft.au=Antonini%2C+J+M%3BYang%2C+H+M%3BMa%2C+J+Y%3BRoberts%2C+J+R%3BBarger%2C+M+W%3BButterworth%2C+L%3BCharron%2C+T+G%3BCastranova%2C+V&rft.aulast=Antonini&rft.aufirst=J&rft.date=2000-11-01&rft.volume=12&rft.issue=11&rft.spage=1017&rft.isbn=&rft.btitle=&rft.title=Inhalation+toxicology&rft.issn=08958378&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-30 N1 - Date created - 2000-11-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Efficacy of agents for pharmacologic conversion of atrial fibrillation and subsequent maintenance of sinus rhythm: a meta-analysis of clinical trials. AN - 71280944; 11093570 AB - Physicians have little evidentiary guidance for pharmacologic agent selection for atrial fibrillation (AF). To assess antiarrhythmic agent efficacy for AF conversion and subsequent maintenance of sinus rhythm (MSR). We searched the clinical trial database of the Cochrane Collaboration and MEDLINE encompassing literature from 1948 to May 1998. We selected 36 (28%) articles eligible as randomized trials of nonpostoperative AF conversion or MSR in adults. Study quality; rates of conversion, MSR, and adverse events were extracted. Compared with control treatment (placebo, verapamil, diltiazem, or digoxin), the odds ratio (OR) for conversion was greatest for ibutilide/dofetilide (OR=29.1; 95% confidence interval [CI], 9.8-86.1) and flecainide (OR=24.7; 95% CI, 9.0-68.3). Less strong but conclusive evidence existed for propafenone (OR=4.6; 95% CI, 2.6-8.2). Quinidine (OR=2.9; 95% CI, 1.2-7.0) had moderate evidence of efficacy for conversion. Disopyramide (OR=7.0; 95% CI, 0.3-153.0) and amiodarone (OR=5.7; 95% CI, 1.0-33.4) had suggestive evidence of efficacy. Sotalol (OR=0.4; 95% CI, 0.0-3.0) had suggestive evidence of negative efficacy. For MSR, strong evidence of efficacy existed for quinidine (OR=4.1; 95% CI, 2.5-6.7), disopyramide (OR=3.4; CI, 1.6-7.1), flecainide (OR=3.1; 95% CI, 1.5-6.2), propafenone (OR=3.7; 95% CI, 2.4-5.7), and sotalol (OR=7.1; 95% CI, 3.8-13.4). The only amiodarone data, from comparison with disopyramide, provided moderate evidence of efficacy for MSR. No trial evaluated procainamide. Direct agent comparisons and adverse event data were limited. Although multiple antiarrhythmic agents had strong evidence of efficacy compared with control treatment for MSR, ibutilide/dofetilide and flecainide had particularly strong evidence of efficacy compared with control treatment for AF conversion. There is sparse and inconclusive evidence on direct agent comparisons and adverse event rates. Obtaining information regarding these relative efficacies should be a research priority. JF - The Journal of family practice AU - Miller, M R AU - McNamara, R L AU - Segal, J B AU - Kim, N AU - Robinson, K A AU - Goodman, S N AU - Powe, N R AU - Bass, E B AD - Division of Pediatric Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. mmiller@ahrq.gov Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 1033 EP - 1046 VL - 49 IS - 11 SN - 0094-3509, 0094-3509 KW - Anti-Arrhythmia Agents KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - Randomized Controlled Trials as Topic KW - Evidence-Based Medicine KW - Humans KW - Aged KW - Middle Aged KW - Atrial Fibrillation -- drug therapy KW - Anti-Arrhythmia Agents -- adverse effects KW - Anti-Arrhythmia Agents -- therapeutic use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71280944?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+family+practice&rft.atitle=Efficacy+of+agents+for+pharmacologic+conversion+of+atrial+fibrillation+and+subsequent+maintenance+of+sinus+rhythm%3A+a+meta-analysis+of+clinical+trials.&rft.au=Miller%2C+M+R%3BMcNamara%2C+R+L%3BSegal%2C+J+B%3BKim%2C+N%3BRobinson%2C+K+A%3BGoodman%2C+S+N%3BPowe%2C+N+R%3BBass%2C+E+B&rft.aulast=Miller&rft.aufirst=M&rft.date=2000-11-01&rft.volume=49&rft.issue=11&rft.spage=1033&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+family+practice&rft.issn=00943509&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-12-08 N1 - Date created - 2000-12-08 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: ACP J Club. 2001 Jul-Aug;135(1):13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Improving Substance Abuse Treatment: The National Treatment Plan Initiative. Changing the Conversation. AN - 62347513; ED450296 AB - This report is the result of five expert panels and six regional public hearings around the country that focused on key persistent issues that have characterized discussions of substance abuse over the years: closing the treatment gap; reducing stigma and changing attitudes; improving and strengthening treatment systems; connecting services and research; and addressing workforce issues. Of particular interest is the Report of Panel V: Addressing Workforce Issues. Panel V identified three types of current workforce issues: education and training; credentialing; and supply, demand, and distribution. The objective of professionals to guarantee universal delivery of optimum standards of care, together with the recent connection between provider reimbursement and education levels, calls for a formal strategy and defines standards for educating and training substance abuse staff. The field also needs a cohesive and unified approach to counseling. Anecdotal evidence of staff shortages exists. The recommendations offered for alleviating these problems fall into three categories: those that address the need for a Federal agency, with responsibility for workforce-related issues such as education and development; those that seek to strengthen the workforce infrastructure in the substance abuse treatment system; and those that require implementation at a field and/or program level. (MKA) Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 308 PB - U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment. KW - ERIC, Resources in Education (RIE) KW - Substance Abuse KW - Counselor Training KW - Professional Training KW - Labor Force KW - Drug Education KW - Certification KW - Outcomes of Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62347513?accountid=14244 LA - English DB - ERIC N1 - Availability - Level 1 - Available online, if indexed January 1993 onward N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - Healthy Children Are Ready To Learn: Promoting Health Insurance for Your Students. A Step-by-Step Guide for School Districts. AN - 62257546; ED461421 AB - Health problems impede the academic performance of many children. Schools are in a unique position to help their state's Medicaid and children's health insurance programs connect with parents who lack health insurance for their children. This guide provides suggestions for identifying eligible children, informing parents of free or low-cost insurance programs, and referring parents to their state's insurance program. Designed to help school districts participate in the outreach effort, the guide offers plans for several levels of involvement, from supporting the outreach efforts of others to conducting their own campaign. Part 1 of the guide outlines how schools can make health insurance available to students through: (1) distributing information about health insurance for children and adolescents; (2) identifying children who need health insurance; and (3) partnering with other agencies to secure health insurance for students. Part 2 lists resources for finding more information on developing health insurance outreach programs, including state contacts for Medicaid and state children's health insurance programs. Part 3 of the guide contains numerous tools, such as sample letters, tips on implementation, and prototype documents to support a district's selected outreach approach. (KB) Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 67 PB - Health Care Financing Administration, 7500 Security Blvd., Baltimore, MD 21244-1850 (HCFA Pub. No. 02196). KW - Childrens Health Insurance Program KW - Medicaid KW - ERIC, Resources in Education (RIE) KW - Administrators KW - Practitioners KW - Program Descriptions KW - Outreach Programs KW - Health Insurance KW - Family School Relationship KW - Program Implementation KW - Enrollment KW - Child Health KW - Agency Cooperation KW - Elementary Secondary Education KW - Children KW - Adolescents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62257546?accountid=14244 LA - English DB - ERIC N1 - Availability - Level 1 - Available online, if indexed January 1993 onward N1 - SuppNotes - For related document on health insurance for child N1 - Last updated - 2014-03-21 ER - TY - GEN T1 - Ready, Set, Learn: Promoting Health Insurance for Children. A Guide for Schools. AN - 62253322; ED461422 AB - Health problems impede the academic performance of 12 percent of students. Schools are in a unique position to help their state's Medicaid and children's health insurance programs connect with parents who lack health insurance for their children. This booklet provides suggestions to help school staff identify, inform, and help to enroll families who need health insurance. The booklet presents information on the following outreach activities for schools: (1) making sure parents have materials on children's health insurance; (2) telling parents that free or low-cost health insurance is available for their children (includes tips for talking with parents); (3) distributing information at parent functions or sending it home; (4) identifying children who may lack insurance and passing along the names, focusing on the use of emergency contact cards; and (5) hosting outreach workers or application assistants from a partner organization. The booklet also describes creative, proactive strategies taken in four school districts to insure children in their schools and delineates suggestions for keeping track of the school's outreach activities. (KB) Y1 - 2000/11// PY - 2000 DA - November 2000 SP - 16 PB - Health Care Financing Administration, 7500 Security Blvd., Baltimore, MD 21244-1850 (HCFA Pub. No. 02196). KW - Childrens Health Insurance Program KW - Medicaid KW - ERIC, Resources in Education (RIE) KW - Administrators KW - Practitioners KW - Program Descriptions KW - Outreach Programs KW - Health Insurance KW - Family School Relationship KW - Child Advocacy KW - Enrollment KW - Child Health KW - Agency Cooperation KW - Program Evaluation KW - Children UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62253322?accountid=14244 LA - English DB - ERIC N1 - Availability - Level 1 - Available online, if indexed January 1993 onward N1 - SuppNotes - For related document on health insurance for child N1 - Last updated - 2014-03-21 ER - TY - BOOK T1 - Healthy people, 2010 AN - 59860473; 2003-1100010 AB - Describes 10-year national public health goals, divided into 467 objectives in 28 focus areas; includes extensive statistical data; US. V. 1, Understanding and improving health, Objectives for improving health (Part A: Focus areas 1-14); v. 2, Objectives for improving health (Part B: Focus Areas 15-28), Appendices. Also available on CD-ROM and on the Internet. JF - United States Department of Health and Human Services, November 2000. 2v. Y1 - 2000/11// PY - 2000 DA - November 2000 PB - United States Department of Health and Human Services KW - United States -- Health conditions -- Statistics KW - Public health -- United States KW - Medicine, Preventive -- United States KW - United States -- Health policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59860473?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/PAIS+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2000-11-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Healthy+people%2C+2010&rft.title=Healthy+people%2C+2010&rft.issn=&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2006-09-28 N1 - Availability - U S Dept Health and Human Services pa U.S. $70; elsewhere $87.50 N1 - Document feature - bibl(s), chart(s), index(es), map(s), table(s) N1 - SuppNotes - 2d ed. 2v N1 - Last updated - 2016-09-28 ER - TY - BOOK T1 - Glass eels from Hainam Island and Guangdong Province, southern China AN - 20722508; 6912643 AB - A total of 31 anguillid glass eels were collected by fishermen along the east coast of Hainan Island and along the northeast coast of the Guangdong Province in southern China in January 1996. The glass eels were identified as six Anguilla japonica and 26 A. marmorata based on morphological characters (Tabeta et al. 1976). The A. japonica glass eels that were collected at the Guangdong Province, town of Tangwei, ranged from 51.0 to 57.0 mm in total length (TL). This is one of the southern most distribution records of A. japonica glass eels. The A. marmorata glass eels that were collected on Hainan Island and at Guangdong Province, ranged from 45.0 to 52.0 mm TL. These specimens all had early stages of pigmentation (VA-VIA2). The ages at recruitment of the A. japonica glass eels examined ranged from 145 to 209 (178.0 plus or minus 23 d; mean plus or minus SD). The duration of the leptocephalus, metamorphosing leptocephalus and glass eel stages in seawater were 144.3 plus or minus 23 d, 21 plus or minus 5 d and 17 plus or minus 9 d, respectively. Ages at recruitment of the A. marmorata glass eels examined ranged from 168 to 230 (189.5 plus or minus 21 d). The duration of the leptocephalus, metamorphosing leptocephalus and glass eel stages in seawater were 137.5 plus or minus 15 d, 25 plus or minus 3 d and 21 plus or minus 8 d, respectively. The hatching dates of both species were estimated to be from May to August. The duration of leptocephalus and glass eel stages in seawater of these species were relatively longer than indicated by data from previous studies on glass eel recruitment in Taiwan and Japan. The surface circulation in the South China Sea is much more variable than the steady northward flow of the Kuroshio Current and may result in a longer transport time to reach the south coast of China than to reach Japan. JF - Abstracts of papers presented at the 3rd East Asian Symposium on Eel Research. Sustainability of Resources and Aquaculture of Eels. Taiwan Fisheries Research Institute, November 16-18, 2000, Keelung, Taiwan. AU - Osame Tabeta AU - Setiawan, I E AU - Mochioka, Noritaka Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 1 EP - 32 KW - Sustainability Science Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Anguilla marmorata KW - Age KW - Age at recruitment KW - distribution records KW - Seawater KW - Population dynamics KW - Aquaculture KW - Fish larvae KW - ISEW, China, People's Rep., Guangdong Prov. KW - Islands KW - Transportation KW - ISEW, China, People's Rep., Hainan Prov., Hainan I. KW - Water currents KW - recruitment KW - sustainability KW - Marine KW - Pigmentation KW - surface circulation KW - hatching KW - Developmental stages KW - Currents KW - Coastal zone KW - ISEW, Taiwan KW - ISEW, China, People's Rep., Guangdong Province KW - ISEW, South China Sea KW - towns KW - Anguilla japonica KW - INW, Donghai Sea, Kuroshio Current KW - ISEW, Taiwan, Keelung KW - Size distribution KW - M3 1010:Issues in Sustainable Development KW - Q1 08442:Population dynamics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20722508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Sustainability+Science+Abstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Osame+Tabeta%3BSetiawan%2C+I+E%3BMochioka%2C+Noritaka&rft.aulast=Osame+Tabeta&rft.aufirst=&rft.date=2000-11-01&rft.volume=&rft.issue=&rft.spage=32&rft.isbn=&rft.btitle=Glass+eels+from+Hainam+Island+and+Guangdong+Province%2C+southern+China&rft.title=Glass+eels+from+Hainam+Island+and+Guangdong+Province%2C+southern+China&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-06-01 N1 - SuppNotes - Physical medium: Printed matter; Summary only., Presumably published in 2001 N1 - Last updated - 2014-05-07 ER - TY - RPRT T1 - Healthy People 2010. Volume 2: Objectives for Improving Health (Part B: Focus Areas 15-28); Appendices AN - 18162866; 4831064 AB - Healthy People 2010, Volume II; Healthy People 2010: Objectives for Improving Health (Part B); Injury and Violence Prevention; Maternal, Infant, Child, and Adolescent Deaths; Medical Product Safety; Mental health and mental Disorders; Nutrition and Overweight; Occupational Safety and Health; Oral Health; Physical Activity and Fitness; Public Health Infrastructure; Respiratory Diseases; Sexually Transmitted Diseases; Substance Abuse; Tobacco Use; Vision and Hearing; Appendices; Healthy People 2010, Volume 1; Message from the Secretary; Foreword; Reader's Guide; Healthy People 2010: Understanding and Improving Health; Healthy People 2010: Objectives for Improving Health (Part A); Access to Quality Health Services; Arthritis, Osteoporosis, and Chronic Back Conditions; Cancer; Chronic Kidney Disease; Diabetes; Disability and Secondary Conditions; Education and Community-Based Programs; Health Care Setting; Community Setting and Select Populations; Environmental Health; Family Planning; Food Safety; Health Communication; Heart Disease and Stroke; HIV; Immunization and Infectious Diseases; Index. Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 672 KW - Physical Education Index KW - PB2001101845 KW - Health KW - Diseases KW - Nutrition KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18162866?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Physical+Education+Index&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=report&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2000-11-01&rft.volume=&rft.issue=&rft.spage=672&rft.isbn=0160504996&rft.btitle=Healthy+People+2010.+Volume+2%3A+Objectives+for+Improving+Health+%28Part+B%3A+Focus+Areas+15-28%29%3B+Appendices&rft.title=Healthy+People+2010.+Volume+2%3A+Objectives+for+Improving+Health+%28Part+B%3A+Focus+Areas+15-28%29%3B+Appendices&rft.issn=&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2006-11-01 N1 - SuppNotes - Available from NTIS: 1-800-553-NTIS (USA); (703)605-6000 (other countries); fax at (703)605-6900; orders[at]ntis.fedworld.gov. NTIS Prices: PC A99/MF A06 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Roof monitoring helps prevent injuries in stone mines AN - 17864180; 5110216 AB - From 1990 to 1996, 16 states reported 92 injuries from falls of roof, rib or face in the more than 90 underground stone mines in the United States. Missouri, Pennsylvania and Kentucky accounted for 48% of the total number of injuries. Of this total, 11 miners were killed. Of the 11 fatalities, 10, or 91%, were associated with unrecognized loose or failed rock within the roof beam. Additionally, unrecognized roof beam failures resulted in a majority of the falls of ground injuries occurring in underground US stone mines from 1990 to 1996. This number is not large in magnitude. But a work force of fewer than 2,000 miners makes for a high fatal-accident rate. JF - Mining Engineering AU - Iannacchione, A T AU - Prosser, L J AU - Grau, R AU - Oyler, D C AU - Dolinar AU - Marshall, TE AU - Compton, C S AD - US National Institute for Occupational Safety and Health, Pittsburgh Research Center, Cochrans Mill Road, Pittsburgh, PA 15236, USA Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 32 EP - 37 VL - 52 IS - 11 SN - 0026-5187, 0026-5187 KW - USA, Kentucky KW - USA, Missouri KW - USA, Pennsylvania KW - falls KW - Health & Safety Science Abstracts KW - Mortality KW - Accidents KW - Injuries KW - Occupational safety KW - Mining KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17864180?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mining+Engineering&rft.atitle=Roof+monitoring+helps+prevent+injuries+in+stone+mines&rft.au=Iannacchione%2C+A+T%3BProsser%2C+L+J%3BGrau%2C+R%3BOyler%2C+D+C%3BDolinar%3BMarshall%2C+TE%3BCompton%2C+C+S&rft.aulast=Iannacchione&rft.aufirst=A&rft.date=2000-11-01&rft.volume=52&rft.issue=11&rft.spage=32&rft.isbn=&rft.btitle=&rft.title=Mining+Engineering&rft.issn=00265187&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Occupational safety; Injuries; Mortality; Accidents; Mining ER - TY - JOUR T1 - Effects of the seafood toxin domoic acid on glutamate uptake by rat astrocytes AN - 17765064; 4820670 AB - Pronounced glutamic acid uptake was observed after only 15 min with glutamate concentrations of 60 nmol/mg protein when astrocytes were incubated with 1 mM glutamic acid. The uptake increased with time to a steady-state glutamate level of above 160 nmol/mg protein by 45 min. The uptake was energy dependent. Reduced temperature (0 degree C) and ouabain (100 mu M) inhibited uptake by 86.7% (P < 0.001; n = 18) and 84.4% (P < 0.001; n = 18), respectively, when compared with controls. After exposure of astrocytes to glutamate (1 mM) in the incubation medium, in the presence of domoic acid (10 and 100 mu M) at 5 and 60 min, domoic acid (10 mu M) elevated glutamate uptake by 64.0% (P < 0.05; n = 34) at 5 min but decreased glutamate uptake by 47.8% (P < 0.01; n = 19) at 60 min compared with controls. A higher dose of domoic acid (100 mu M) decreased glutamate uptake by 49.6% (P < 0.01; n = 20) and 61.3% (P < 0.001; n = 20) at 5 and 60 min, respectively, compared with controls. This study suggests that domoic acid may induce neurotoxicity because of the failure of astrocytes to remove extracellular glutamate. This may contribute to excitotoxic injury. JF - Food and Chemical Toxicology AU - Ross, IA AU - Johnson, W AU - Sapienza, P P AU - Kim, C S AD - Division of Toxicological Research (HFS-506), Center for Food Safety and Applied Nutrition, Food and Drug Administration, Washington, DC 20204, USA, CSK@vm.cfsan.fda.gov Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 1005 EP - 1011 VL - 38 IS - 11 SN - 0278-6915, 0278-6915 KW - rats KW - Toxicology Abstracts KW - Astrocytes KW - Domoic acid KW - Neurotoxicity KW - Glutamic acid KW - Food contamination KW - Toxins KW - X 24120:Food, additives & contaminants KW - X 24172:Plants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17765064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+and+Chemical+Toxicology&rft.atitle=Effects+of+the+seafood+toxin+domoic+acid+on+glutamate+uptake+by+rat+astrocytes&rft.au=Ross%2C+IA%3BJohnson%2C+W%3BSapienza%2C+P+P%3BKim%2C+C+S&rft.aulast=Ross&rft.aufirst=IA&rft.date=2000-11-01&rft.volume=38&rft.issue=11&rft.spage=1005&rft.isbn=&rft.btitle=&rft.title=Food+and+Chemical+Toxicology&rft.issn=02786915&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Domoic acid; Glutamic acid; Astrocytes; Toxins; Neurotoxicity; Food contamination ER - TY - JOUR T1 - Traumatic Injury Among Drywall Installers, 1992 to 1995 AN - 17744045; 4805123 AB - This study examined the traumatic-injury characteristics associated with one of the high-risk occupations in the construction industry--drywall installers--through an analysis of the traumatic-injury data obtained from the Bureau of Labor Statistics. An additional objective was to demonstrate a feasible and economic approach to identify risk factors associated with a specific occupation by using an existing database. An analysis of nonfatal traumatic injuries with days away from work among wage-and-salary drywall installers was performed for 1992 through 1995 using the Occupational Injury and Illness Survey conducted by the Bureau of Labor Statistics. Results from this study indicate that drywall installers are at a high risk of overexertion and falls to a lower level. More than 40% of the injured drywall installers suffered sprains, strains, and/or tears. The most frequently injured body part was the trunk. More than one-third of the trunk injuries occurred while handling solid building materials, mainly drywall. In addition, the database analysis used in this study is valid in identifying overall risk factors for specific occupations. JF - Journal of Occupational and Environmental Medicine AU - Chiou, S S AU - Pan, C S AU - Keane, P AD - National Institute for Occupational Safety and Health, 1095 Willowdale Rd. MS- P119, Morgantown, WV 26505, USA, schiou@cdc.gov Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 1101 EP - 1108 VL - 42 IS - 11 SN - 1076-2752, 1076-2752 KW - drywall installers KW - Health & Safety Science Abstracts; Risk Abstracts KW - Risk assessment KW - Injuries KW - Occupational safety KW - Hazards KW - Accidents KW - Construction industry KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17744045?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Traumatic+Injury+Among+Drywall+Installers%2C+1992+to+1995&rft.au=Chiou%2C+S+S%3BPan%2C+C+S%3BKeane%2C+P&rft.aulast=Chiou&rft.aufirst=S&rft.date=2000-11-01&rft.volume=42&rft.issue=11&rft.spage=1101&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Accidents; Injuries; Construction industry; Occupational safety; Hazards; Risk assessment ER - TY - JOUR T1 - Controlled Flight into Terrain Accidents Among Commuter and Air Taxi Operators in Alaska AN - 17741579; 4808362 AB - Between 1990 and 1998, aviation accidents in Alaska caused 100 occupational pilot deaths (equivalent to 430/100,000 pilots/year, approximately 86 times the overall U.S. worker fatality rate). Although Alaskan geography and climate increase aviation risks, many accidents were attributed to pilot error. While most accidents occurred during takeoff/landing, most fatalities resulted from Controlled Flight Into Terrain (CFIT). The purpose of this study was to examine risk factors for CFIT. Using National Transportation Safety Board airplane accident data we identified CFIT from flight phase and event description fields, and calculated odds ratios for CFIT/non-CFIT accidents for visual conditions, aircraft features, and pilot experience. Between 1991 and 1998, 351 single aircraft commuter and air taxi accidents occurred in Alaska; 59 (17%) were CFIT. Of 140 total fatalities, 82 (59%) occurred in 30 CFIT accidents. There was a twelve-fold risk for death in CFIT vs. non-CFIT accidents (OR = 12.42, 95% CI = 8.19-18.88). Accidents while flying Visual Flight Rules (VFR) into poor visibility were more likely CFIT than non-CFIT (Odds ratio = 46.06, Confidence Interval = 19.32-112.46), and caused 37% of all deaths. Additionally, flights in Instrument Meteorological Conditions (IMC) were 47 times more likely to be CFIT than non-CFIT. No risk for CFIT was shown for flight hours, number of engines, passenger presence, or pilot age. All CFIT were attributed to pilot error, often for continuing VFR into poor visibility. CFIT caused most aviation deaths. Further research into human factors contributing to CFIT is needed. Implementation of global- positioning, ground-proximity/avoidance technology, might reduce CFIT incidence. JF - Aviation, Space and Environmental Medicine AU - Thomas, T K AU - Bensyl, D M AU - Manwaring, J C AU - Conway, G A AD - CDC/NIOSH, 4230 University Drive #310, Anchorage, AK 99508, USA, Dbensyl@cdc.gov Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 1098 EP - 1103 VL - 71 IS - 11 SN - 0095-6562, 0095-6562 KW - USA, Alaska KW - crew safety KW - pilots KW - Health & Safety Science Abstracts KW - Mortality KW - Accidents KW - Aircraft KW - Injuries KW - Occupational safety KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17741579?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aviation%2C+Space+and+Environmental+Medicine&rft.atitle=Controlled+Flight+into+Terrain+Accidents+Among+Commuter+and+Air+Taxi+Operators+in+Alaska&rft.au=Thomas%2C+T+K%3BBensyl%2C+D+M%3BManwaring%2C+J+C%3BConway%2C+G+A&rft.aulast=Thomas&rft.aufirst=T&rft.date=2000-11-01&rft.volume=71&rft.issue=11&rft.spage=1098&rft.isbn=&rft.btitle=&rft.title=Aviation%2C+Space+and+Environmental+Medicine&rft.issn=00956562&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Accidents; Injuries; Mortality; Aircraft; Occupational safety ER - TY - JOUR T1 - The NIOSH/FAA working women's health study: Evaluation of the cosmic-radiation exposures of flight attendants AN - 17732322; 4798542 AB - Air crew are exposed to elevated levels of cosmic ionizing radiation of galactic and solar origin and are among the more highly exposed occupational groups to ionizing radiation in the United States. Depending on flight route patterns, the annual dose may range from 0.2 to 5 mSv. By comparison, the average annual radiation dose equivalent of occupationally exposed adults in the United States is estimated to be 1.1 mSv. Cosmic-radiation dose depends primarily on altitude and geomagnetic latitude and to a lesser degree on solar activity. Although the International Commission on Radiological Protection has recommended that air crew exposures to natural radiation in-flight be treated as occupational exposures, United States flight crew exposures to natural cosmic radiation are not regulated or typically monitored. There are approximately 148,000 air crew (flight deck crew and flight attendants) in the United States. JF - Health Physics AU - Waters, M AU - Bloom, T F AU - Grajewski, B AD - National Institute for Occupational Safety and Health, 4676 Columbia Parkway R-14, Cincinnati, OH 45226-1998, USA Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 553 EP - 559 VL - 79 IS - 5 SN - 0017-9078, 0017-9078 KW - flight attendants KW - crew safety KW - Pollution Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - Aircraft KW - Dose-response effects KW - Occupational exposure KW - Cosmic radiation KW - R2 23080:Industrial and labor KW - H 8000:Radiation Safety/Electrical Safety KW - P 8000:RADIATION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17732322?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=The+NIOSH%2FFAA+working+women%27s+health+study%3A+Evaluation+of+the+cosmic-radiation+exposures+of+flight+attendants&rft.au=Waters%2C+M%3BBloom%2C+T+F%3BGrajewski%2C+B&rft.aulast=Waters&rft.aufirst=M&rft.date=2000-11-01&rft.volume=79&rft.issue=5&rft.spage=553&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Occupational exposure; Cosmic radiation; Aircraft; Dose-response effects ER - TY - JOUR T1 - Dietary Genistein Inactivates Rat Thyroid Peroxidase in Vivo without an Apparent Hypothyroid Effect AN - 17727065; 4795913 AB - Biological effects of genistein are currently under investigation by the National Toxicology Program because of widespread and increasing soy consumption by humans and evidence for modulation of endocrine function. Rats were exposed to genistein aglycone in soy-free feed fortified at 0, 5, 100, and 500 ppm starting in utero through 20 weeks. Thyroid glands and serum were analyzed for total genistein (aglycone + conjugates) using HPLC with electrospray mass spectrometric detection. Microsomal thyroid peroxidase (TPO) activity was measured spectrophotometrically. The total genistein content in rat serum was as high as 8 mu M, and significant dose-dependent increases of genistein in thyroid tissue up to 1 pmol/mg were found in male and female rats. The activity of TPO in male and female rats was found to be reduced by up to 80% in a dose-dependent manner. Male and female rats consuming a standard soy-based rodent diet (NIH 31) had TPO activity approximately 50% lower than rats consuming a soy-free diet and this loss was commensurate with measured serum levels of isoflavones. Suicide inactivation of rat, porcine, and human TPO was observed in vitro at concentrations of genistein aglycone comparable to those measured in rat thyroids. Thyroid hormone levels (T3, T4, TSH) in serum, thyroid weights, and histopathology showed no differences between treated and untreated groups. These findings suggest that, even though substantial amounts of TPO activity are lost concomitant to soy isoflavone consumption by normal rats, the remaining enzymatic activity is sufficient to maintain thyroid homeostasis in the absence of additional perturbations. JF - Toxicology and Applied Pharmacology AU - Chang, H C AU - Doerge AD - Division of Biochemical Toxicology, Jefferson, 72079, Arkansas, ddoerge@nctr.fda.gov Y1 - 2000/11/01/ PY - 2000 DA - 2000 Nov 01 SP - 244 EP - 252 PB - Academic Press VL - 168 IS - 3 SN - 0041-008X, 0041-008X KW - rats KW - Toxicology Abstracts KW - Peroxidase KW - Hypothyroidism KW - Thyroid hormone KW - Endocrine system KW - Dietary intake KW - X 24172:Plants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17727065?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Dietary+Genistein+Inactivates+Rat+Thyroid+Peroxidase+in+Vivo+without+an+Apparent+Hypothyroid+Effect&rft.au=Chang%2C+H+C%3BDoerge&rft.aulast=Chang&rft.aufirst=H&rft.date=2000-11-01&rft.volume=168&rft.issue=3&rft.spage=244&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1006%2Ftaap.2000.9019 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Dietary intake; Thyroid hormone; Hypothyroidism; Peroxidase; Endocrine system DO - http://dx.doi.org/10.1006/taap.2000.9019 ER - TY - JOUR T1 - Biotransformation of the isoflavonoids biochanin A, formononetin, and glycitein by Eubacterium limosum AN - 17722432; 4782100 AB - Eubacterium limosum (ATCC 8486), a strict anaerobe from the human intestinal tract that is capable of O-demethylation of several compounds, was tested for the ability to metabolize three methoxylated isoflavonoids, biochanin A, formononetin, and glycitein. High-performance liquid chromatography elution profiles of metabolites produced from biochanin A, formononetin, and glycitein showed peaks that had identical retention times to authentic genistein, daidzein, and 6,7,4'-trihydroxyisoflavone, respectively. The metabolites were identified, using an on line liquid chromatography-electrospray mass spectrometer. E. limosum produced 61.4 mu M of genistein and 13.2 mu M of daidzein from 100 mu M of biochanin A and formononetin, after 26 days incubation. O-demethylase activity is cell-associated and was not detected in the extracellular fraction of bacterial culture. This is the first study in which conversion of biochanin A, and formononetin to more potent phytoestrogens by a bacterium has been shown. JF - FEMS Microbiology Letters AU - Hur, H-G AU - Rafii, F AD - Division of Microbiology, National Center for Toxicological Research, US FDA, Jefferson, AR 72079, USA, frafii@nctr.fda.gov Y1 - 2000/11/01/ PY - 2000 DA - 2000 Nov 01 SP - 21 EP - 25 PB - Elsevier VL - 192 IS - 1 SN - 0378-1097, 0378-1097 KW - biotransformation KW - biochanin A KW - formononetin KW - genistein KW - glycitein KW - Microbiology Abstracts B: Bacteriology KW - Biodegradation KW - Eubacterium limosum KW - J 02722:Biodegradation, growth, nutrition and leaching UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17722432?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Microbiology+Letters&rft.atitle=Biotransformation+of+the+isoflavonoids+biochanin+A%2C+formononetin%2C+and+glycitein+by+Eubacterium+limosum&rft.au=Hur%2C+H-G%3BRafii%2C+F&rft.aulast=Hur&rft.aufirst=H-G&rft.date=2000-11-01&rft.volume=192&rft.issue=1&rft.spage=21&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Letters&rft.issn=03781097&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Eubacterium limosum; Biodegradation ER - TY - JOUR T1 - Environmental investigations of Vibrio parahaemolyticus in oysters after outbreaks in Washington, Texas, and New York (1997 and 1998) AN - 17035122; 4795427 AB - Total Vibrio parahaemolyticus densities and the occurrence of pathogenic strains in shellfish were determined following outbreaks in Washington, Texas, and New York. Recently developed nonradioactive DNA probes were utilized for the first time for direct enumeration of V. parahaemolyticus in environmental shellfish samples. V. parahaemolyticus was prevalent in oysters from Puget Sound, Wash.; Galveston Bay, Tex.; and Long Island Sound, N.Y., in the weeks following shellfish-associated outbreaks linked to these areas. However, only two samples (one each from Washington and Texas) were found to harbor total V. parahaemolyticus densities exceeding the level of concern of 10,000 g super(-1). Pathogenic strains, defined as those hybridizing with tdh and/or trh probes, were detected in a few samples, mostly Puget Sound oysters, and at low densities (usually 10 g super(-1) tdh- and/or trh-positive V. parahaemolyticus in environmental oysters should be considered extraordinary. JF - Applied and Environmental Microbiology AU - DePaola, A AU - Kaysner, CA AU - Bowers, J AU - Cook, D W AD - Gulf Coast Seafood Laboratory, U.S. Food and Drug Administration, Dauphin Island, AL 36528-0158, USA, adepaola@cfsan.fda.gov Y1 - 2000/11// PY - 2000 DA - Nov 2000 SP - 4649 EP - 4654 VL - 66 IS - 11 SN - 0099-2240, 0099-2240 KW - USA, New York KW - USA, Texas KW - USA, Washington KW - Vibrio parahaemolyticus KW - enumeration KW - gastroenteritis KW - tdh gene KW - trh gene KW - Oceanic Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Health & Safety Science Abstracts; Pollution Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Environments KW - Human food KW - Pollution effects KW - Microbial contamination KW - Public health KW - Microbiological analysis KW - Seafood KW - Marine KW - Ostreidae KW - ANW, USA, Long Island Sound KW - Pathogenic bacteria KW - Poisoning KW - Brackish KW - Food poisoning KW - Food contamination KW - ASW, USA, Texas, Galveston Bay KW - Hybridization analysis KW - ANW, USA, New York KW - Marine pollution KW - DNA KW - INE, USA, Washington, Puget Sound KW - Gastroenteritis KW - Oyster fisheries KW - O 5040:Processing, Products and Marketing KW - Q1 08201:General KW - O 1010:Viruses, Bacteria, Protists, Fungi and Plants KW - A 01017:Human foods KW - J 02704:Enumeration KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 4000:Food and Drugs KW - P 6000:TOXICOLOGY AND HEALTH KW - Q1 08627:Food quality and standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17035122?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Environmental+investigations+of+Vibrio+parahaemolyticus+in+oysters+after+outbreaks+in+Washington%2C+Texas%2C+and+New+York+%281997+and+1998%29&rft.au=DePaola%2C+A%3BKaysner%2C+CA%3BBowers%2C+J%3BCook%2C+D+W&rft.aulast=DePaola&rft.aufirst=A&rft.date=2000-11-01&rft.volume=66&rft.issue=11&rft.spage=4649&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2014-05-06 N1 - SubjectsTermNotLitGenreText - Pathogenic bacteria; Human food; Food poisoning; Microbial contamination; Oyster fisheries; Microbiological analysis; Environments; DNA; Seafood; Gastroenteritis; Hybridization analysis; Marine pollution; Poisoning; Pollution effects; Food contamination; Public health; Ostreidae; ANW, USA, New York; ANW, USA, Long Island Sound; INE, USA, Washington, Puget Sound; ASW, USA, Texas, Galveston Bay; Marine; Brackish ER - TY - JOUR T1 - Transmission of Norwalk virus during a football game AN - 17647328; 4791765 AB - During a college football game in Florida, diarrhea and vomiting developed in many of the members of a North Carolina team. The next day, similar symptoms developed in some of the players on the opposing team. We interviewed those who ate the five meals served to the North Carolina team before the game and some of the players on the opposing team who became ill. Patients with primary cases were members or staff of the team who had vomiting or diarrhea at least 10 hours after but no more than 50 hours after eating a box lunch served the day before the game. Patients with secondary cases had a later onset of symptoms or had symptoms without having eaten the box lunch. Stool samples were examined by electron microscopy and by a reverse-transcription-polymerase-chain-reaction (RT-PCR) assay. The two football teams shared no food or beverages and had no contact off the playing field. Of five meals served to the North Carolina team before the game, only the box lunch was associated with a significant risk of illness (relative risk of illness, 4.1; 95 percent confidence interval, 1.6 to 10.0). The rate of attack among those who ate the box lunch was 62 percent. There were 11 secondary cases among the members and staff of the North Carolina team and 11 such cases among the Florida players. All four stool samples obtained from North Carolina patients were positive for Norwalk-like virus on electron microscopy. All four samples as well as one of two stool samples from players on the Florida team were positive for a Norwalk-like virus of genogroup I on RT-PCR assay; the RT-PCR products had identical sequences. This investigation documents person-to-person transmission of Norwalk virus among players during a football game. Persons with acute gastroenteritis should be excluded from playing contact sports. JF - New England Journal of Medicine AU - Becker, K M AU - Moe, CL AU - Southwick, K L AU - MacCormack, J N AD - Department of Health and Human Services, Office of International and Refugee Health, Rm. 18-105, Parklawn Bldg., 5600 Fishers Ln., Rockville, MD 20857, USA, kbecker@osophs.dhhs.gov Y1 - 2000/10/26/ PY - 2000 DA - 2000 Oct 26 SP - 1223 EP - 1237 VL - 343 IS - 17 SN - 0028-4793, 0028-4793 KW - football games KW - Norwalk virus KW - USA, Florida KW - contact sports KW - disease transmission KW - food-borne diseases KW - football KW - gastroenteritis KW - outbreaks KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - Outbreaks KW - Gastroenteritis KW - Food-borne diseases KW - Physical training KW - Disease transmission KW - V 22123:Epidemiology KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17647328?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=New+England+Journal+of+Medicine&rft.atitle=Transmission+of+Norwalk+virus+during+a+football+game&rft.au=Becker%2C+K+M%3BMoe%2C+CL%3BSouthwick%2C+K+L%3BMacCormack%2C+J+N&rft.aulast=Becker&rft.aufirst=K&rft.date=2000-10-26&rft.volume=343&rft.issue=17&rft.spage=1223&rft.isbn=&rft.btitle=&rft.title=New+England+Journal+of+Medicine&rft.issn=00284793&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Norwalk virus; Disease transmission; Physical training; Food-borne diseases; Outbreaks; Gastroenteritis ER - TY - JOUR T1 - Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis. AN - 72336764; 10922372 AB - Vanadium is a metal widely distributed in the environment. Although vanadate-containing compounds exert potent toxic effects on a wide variety of biological systems, the mechanisms controlling vanadate-induced adverse effects remain to be elucidated. The present study investigated the vanadate-induced p53 activation and involvement of reactive oxygen species (ROS) in p53 activation as well as the role of p53 in apoptosis induction by vanadate. Exposure of mouse epidermal JB6 cells to vanadate led to transactivation of p53 activity in a time- and dose-dependent manner. It also caused mitochondrial damage, apoptosis, and generated ROS. Scavenging of vanadate-induced H(2)O(2) by N-acetyl-l-cysteine (a general antioxidant) or catalase (a specific H(2)O(2) inhibitor), or the chelation of vanadate by deferoxamine, resulted in inhibition of p53 activation and cell mitochondrial damage. In contract, an increase in H(2)O(2) generation in response to superoxide dismutase or NADPH enhanced these effects caused by vanadate. Furthermore, vanadate-induced apoptosis occurred in cells expressing wild-type p53 (p53+/+) but was very weak in p53-deficient (p53-/-) cells. These results demonstrate that vanadate induces p53 activation mainly through H(2)O(2) generation, and this activation is required for vanadate-induced apoptosis. JF - The Journal of biological chemistry AU - Huang, C AU - Zhang, Z AU - Ding, M AU - Li, J AU - Ye, J AU - Leonard, S S AU - Shen, H M AU - Butterworth, L AU - Lu, Y AU - Costa, M AU - Rojanasakul, Y AU - Castranova, V AU - Vallyathan, V AU - Shi, X AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA. Y1 - 2000/10/20/ PY - 2000 DA - 2000 Oct 20 SP - 32516 EP - 32522 VL - 275 IS - 42 SN - 0021-9258, 0021-9258 KW - Reactive Oxygen Species KW - 0 KW - Tumor Suppressor Protein p53 KW - Vanadates KW - 3WHH0066W5 KW - Hydrogen Peroxide KW - BBX060AN9V KW - Acetylcysteine KW - WYQ7N0BPYC KW - Index Medicus KW - Reactive Oxygen Species -- metabolism KW - Mitochondria -- physiology KW - Animals KW - Skin KW - Transfection KW - Kinetics KW - Electron Spin Resonance Spectroscopy KW - Membrane Potentials -- physiology KW - Mice KW - Membrane Potentials -- drug effects KW - Intracellular Membranes -- physiology KW - Acetylcysteine -- pharmacology KW - DNA Fragmentation KW - Cell Line KW - Transcription, Genetic -- drug effects KW - Genes, p53 KW - Vanadates -- pharmacology KW - Apoptosis -- physiology KW - Hydrogen Peroxide -- pharmacology KW - Apoptosis -- drug effects KW - Transcriptional Activation -- physiology KW - Transcriptional Activation -- drug effects KW - Tumor Suppressor Protein p53 -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72336764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+biological+chemistry&rft.atitle=Vanadate+induces+p53+transactivation+through+hydrogen+peroxide+and+causes+apoptosis.&rft.au=Huang%2C+C%3BZhang%2C+Z%3BDing%2C+M%3BLi%2C+J%3BYe%2C+J%3BLeonard%2C+S+S%3BShen%2C+H+M%3BButterworth%2C+L%3BLu%2C+Y%3BCosta%2C+M%3BRojanasakul%2C+Y%3BCastranova%2C+V%3BVallyathan%2C+V%3BShi%2C+X&rft.aulast=Huang&rft.aufirst=C&rft.date=2000-10-20&rft.volume=275&rft.issue=42&rft.spage=32516&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+biological+chemistry&rft.issn=00219258&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-20 N1 - Date created - 2000-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of asphalt fume condensate exposure on acute pulmonary responses AN - 17751017; 4813998 AB - Objective: The present study was carried out to characterize the effects of in vitro exposure to paving asphalt fume condensate (AFC) on alveolar macrophage (AM) functions and to monitor acute pulmonary responses to in vivo AFC exposure in rats. Methods: For in vitro studies, rat primary AM cultures were incubated with various concentrations of AFC for 24 h at 37 degree C. AM-conditioned medium was collected and assayed for lactate dehydrogenase (LDH) as a marker of cytotoxicity. Tumor necrosis factor- alpha (TNF- alpha ) and interleukin-1 (IL-1) production were assayed in AM-conditioned medium to monitor AM function. The effect of AFC on chemiluminescence (CL) generated by resting AM or AM in response to zymosan or PMA stimulation was also determined as a marker of AM activity. For in vivo studies, rats received either (1) a single intratracheal (IT) instillation of saline, or 0.1 mg or 0.5 mg AFC and were killed 1 or 3 days later; or (2) IT instillation of saline, or 0.1, 0.5, or 2 mg AFC for three consecutive days and were killed the following day. Differential counts of cells harvested by bronchoalveolar lavage were measured to monitor inflammation. Acellular LDH and protein content in the first lavage fluid were measured to monitor damage. CL generation, TNF- alpha and IL-1 production by AM were assayed to monitor AM function. Results: In vitro AFC exposure at 200 mu g/ml did not induce cytotoxicity, oxidant generation, or IL-1 production by AM, but it did cause a small but significant increase in TNF- alpha release from AM. In vitro exposure of AM to AFC resulted in a significant decline of CL in response to zymosan or PMA stimulation. The in vivo studies showed that AFC exposure did not induce significant neutrophil infiltration or alter LDH or protein content in acellular lavage samples. Macrophages obtained from AFC-exposed rats did not show significant differences in oxidant production or cytokine secretion at rest or in response to LPS in comparison with control macrophages. Conclusions: These results suggest that: (1) in vitro AFC exposure did not adversely affect cell viability or induce the release of high levels of inflammatory cytokines or oxidants; and (2) exposure of rats to AFC did not cause acute pulmonary inflammation or injury, and did not significantly alter AM functions. JF - Archives of Toxicology AU - Ma, J AU - Barger, M AU - Kriech, A AU - Castranova, V AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, West Virginia 26505-2888, USA, jym1@cdc.gov Y1 - 2000/10/17/ PY - 2000 DA - 2000 Oct 17 SP - 452 EP - 459 PB - Springer-Verlag VL - 74 IS - 8 SN - 0340-5761, 0340-5761 KW - sephalt fume condensate KW - alveolar macrophages KW - rats KW - asphalt KW - Toxicology Abstracts KW - Macrophages KW - Fumes KW - Lung KW - Petroleum KW - Alveoli KW - X 24151:Acute exposure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17751017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Toxicology&rft.atitle=Effects+of+asphalt+fume+condensate+exposure+on+acute+pulmonary+responses&rft.au=Ma%2C+J%3BBarger%2C+M%3BKriech%2C+A%3BCastranova%2C+V&rft.aulast=Ma&rft.aufirst=J&rft.date=2000-10-17&rft.volume=74&rft.issue=8&rft.spage=452&rft.isbn=&rft.btitle=&rft.title=Archives+of+Toxicology&rft.issn=03405761&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Alveoli; Fumes; Lung; Macrophages; Petroleum ER - TY - JOUR T1 - DNA adduct formation by Fusarium culture extracts: lack of role of fusarin C. AN - 72320164; 11024453 AB - Fusarium fungi have been shown to infect corn and other crops worldwide, and have a significant impact on human health through loss of crops or contamination of food with mycotoxins. Isolates of Fusarium fungi from an area of South Africa with high incidence of esophageal cancer have been shown to induce esophageal and liver cancer in rats. Several isolates of Fusarium fungi were grown on corn to determine if genotoxic products were produced. We report the incubation of methanol extracts of Fusarium verticillioides cultures with DNA in the presence of rat liver fractions (S9) resulted in the formation of a unique DNA adduct that was detected by (32)P-postlabeling. Fusarin C was purified from cultures of Fusarium verticillioides RRC 415, and was not responsible for the formation of the DNA adduct. Treatment of the methanolic extracts with ultraviolet B radiation reduced the fusarin C content in the extract; however, this had no effect on the formation of the DNA adduct following incubation of the extract with DNA and S9. The unique DNA adduct was formed following the incubation of several Fusarium verticillioides isolates from the US and South Africa, while extracts of cultures of Fusarium graminearium and Fusarium sacchari isolates formed very little of the DNA adduct when incubated with DNA and S9. These data suggest that neither fusarin C nor any of its metabolites are responsible for formation of the DNA adduct, and that an unidentified compound is present in F. verticillioides cultures that forms a DNA adduct, and may be important in the etiology of human esophageal cancer. JF - Chemico-biological interactions AU - Bever, R J AU - Couch, L H AU - Sutherland, J B AU - Williams, A J AU - Beger, R D AU - Churchwell, M I AU - Doerge, D R AU - Howard, P C AD - Division of Biochemical Toxicology, HFT-110, National Center for Toxicological Research, US Food and Drug Administration, US Public Health Service, 3900 NCTR Road, Jefferson, AR 72079-9205, USA. Y1 - 2000/10/16/ PY - 2000 DA - 2000 Oct 16 SP - 141 EP - 157 VL - 128 IS - 2 SN - 0009-2797, 0009-2797 KW - DNA Adducts KW - 0 KW - Mycotoxins KW - Polyenes KW - Tissue Extracts KW - fusarin C KW - 79748-81-5 KW - DNA KW - 9007-49-2 KW - Index Medicus KW - Salmon KW - Drug Stability KW - Animals KW - DNA -- metabolism KW - Liver -- metabolism KW - Male KW - Chromatography, High Pressure Liquid KW - DNA Adducts -- biosynthesis KW - Mycotoxins -- isolation & purification KW - Fusarium -- chemistry KW - Fusarium -- metabolism KW - Polyenes -- toxicity KW - Polyenes -- metabolism KW - Mycotoxins -- metabolism KW - Polyenes -- isolation & purification KW - Mycotoxins -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72320164?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemico-biological+interactions&rft.atitle=DNA+adduct+formation+by+Fusarium+culture+extracts%3A+lack+of+role+of+fusarin+C.&rft.au=Bever%2C+R+J%3BCouch%2C+L+H%3BSutherland%2C+J+B%3BWilliams%2C+A+J%3BBeger%2C+R+D%3BChurchwell%2C+M+I%3BDoerge%2C+D+R%3BHoward%2C+P+C&rft.aulast=Bever&rft.aufirst=R&rft.date=2000-10-16&rft.volume=128&rft.issue=2&rft.spage=141&rft.isbn=&rft.btitle=&rft.title=Chemico-biological+interactions&rft.issn=00092797&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-12-07 N1 - Date created - 2000-11-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Comparison of drug effects on the performance of two timing tasks in rats. AN - 72470769; 11124404 AB - Previous evidence suggests that different timing tasks are differentially sensitive to pharmacological manipulation, especially when different values for the temporal parameters are used. The present series of experiments compared the effects of physostigmine, caffeine, pentobarbital, morphine, and naloxone on the performance of a differential reinforcement of low rates with limited hold (DRL-LH) and a temporal response differentiation (TRD) task. In the DRL-LH task, rats were reinforced for responses that occurred 10-14 s from the end of the previous response. In the TRD task, rats were reinforced for responses with a duration of 10-14 s. The peak response time and peak spread of the initiation time distribution (for DRL-LH) or the response duration distribution (for TRD) were used as indices of temporal discrimination. Physostigmine, caffeine, and pentobarbital produced very similar effects on peak response time for both tasks, but the effects of morphine and naloxone were different for the two tasks. Effects on peak spread for the two tasks did not always correspond to changes in peak response time, suggesting that different processes may be measured by these two endpoints. Further, these effects were independent of changes in response rate suggesting that the effects were not due to gross disruptions in motivation or motor control. These results suggest that the effects of drugs on DRL-LH and TRD performance may differ, even when temporal parameters are identical. JF - Pharmacology, biochemistry, and behavior AU - Popke, E J AU - Mayorga, A J AU - Fogle, C M AU - Paule, M G AD - Division of Neurotoxicology, National Center for Toxicological Research, FDA, HFT-132, 3900 NCTR Road, Jefferson, AR 72079-9502, USA. epopke@nctr.fda.gov Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 377 EP - 385 VL - 67 IS - 2 SN - 0091-3057, 0091-3057 KW - Central Nervous System Stimulants KW - 0 KW - Cholinesterase Inhibitors KW - Hypnotics and Sedatives KW - Narcotic Antagonists KW - Narcotics KW - Naloxone KW - 36B82AMQ7N KW - Caffeine KW - 3G6A5W338E KW - Morphine KW - 76I7G6D29C KW - Physostigmine KW - 9U1VM840SP KW - Pentobarbital KW - I4744080IR KW - Index Medicus KW - Cholinesterase Inhibitors -- pharmacology KW - Animals KW - Naloxone -- pharmacology KW - Analysis of Variance KW - Central Nervous System Stimulants -- pharmacology KW - Dose-Response Relationship, Drug KW - Physostigmine -- pharmacology KW - Caffeine -- pharmacology KW - Narcotics -- pharmacology KW - Hypnotics and Sedatives -- pharmacology KW - Pentobarbital -- pharmacology KW - Morphine -- pharmacology KW - Rats KW - Rats, Sprague-Dawley KW - Time Factors KW - Narcotic Antagonists -- pharmacology KW - Male KW - Behavior, Animal -- drug effects KW - Task Performance and Analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72470769?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacology%2C+biochemistry%2C+and+behavior&rft.atitle=Comparison+of+drug+effects+on+the+performance+of+two+timing+tasks+in+rats.&rft.au=Popke%2C+E+J%3BMayorga%2C+A+J%3BFogle%2C+C+M%3BPaule%2C+M+G&rft.aulast=Popke&rft.aufirst=E&rft.date=2000-10-01&rft.volume=67&rft.issue=2&rft.spage=377&rft.isbn=&rft.btitle=&rft.title=Pharmacology%2C+biochemistry%2C+and+behavior&rft.issn=00913057&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-01 N1 - Date created - 2001-01-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Misclassification of physical work exposures as a design issue for musculoskeletal intervention studies. AN - 72437750; 11103839 AB - This study determined the impact of misclassification due to using job titles as surrogate variables for physical work exposures to assess confounding in a study of the preventive effect of back belts on back injury. The authors present retail merchandise data that quantify misclassification from residual confounding by physical work exposures on injury rate ratios when available administrative job titles are used. Job title and direct observation data on 134 workers were used to calculate the percentage to which the job-title-adjusted rate ratio for back injury accounts for confounding by the true physical work exposures, awkward postures, and heavy weight handling. Workers' compensation data, an estimate of the effect of back belts from the literature, and the percentage of adjustment of the rate ratio due to the job title variable were used to calculate the magnitude of bias from the rate ratio adjusted for job title. The job title variable was found to have sensitivities of 97% and 85% and specificities of 68% and 58% for awkward postures and heavy weight handling, respectively. The magnitude of confounding bias remaining for the back-injury rate ratio when the job title surrogate was used was 24% for postures and 45% for heavy weight handling. The administrative job title performed poorly in this setting; residual confounding was sufficient to bias the rate ratio from 2.0 to 1.3. The effect of additional sources of misclassification and the need for better exposure measures than job title are discussed. JF - Scandinavian journal of work, environment & health AU - Gardner, L I AU - Landsittel, D P AU - Nelson, N A AU - Pan, C S AD - Division of Safety Research, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA. lig0@cdc.gov Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 406 EP - 413 VL - 26 IS - 5 SN - 0355-3140, 0355-3140 KW - Index Medicus KW - Humans KW - Confounding Factors (Epidemiology) KW - Pilot Projects KW - Workers' Compensation -- statistics & numerical data KW - Lifting KW - Models, Theoretical KW - Musculoskeletal Diseases -- prevention & control KW - Occupational Diseases -- prevention & control KW - Back Injuries -- prevention & control KW - Work KW - Occupational Diseases -- epidemiology KW - Bias (Epidemiology) KW - Musculoskeletal Diseases -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72437750?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+journal+of+work%2C+environment+%26+health&rft.atitle=Misclassification+of+physical+work+exposures+as+a+design+issue+for+musculoskeletal+intervention+studies.&rft.au=Gardner%2C+L+I%3BLandsittel%2C+D+P%3BNelson%2C+N+A%3BPan%2C+C+S&rft.aulast=Gardner&rft.aufirst=L&rft.date=2000-10-01&rft.volume=26&rft.issue=5&rft.spage=406&rft.isbn=&rft.btitle=&rft.title=Scandinavian+journal+of+work%2C+environment+%26+health&rft.issn=03553140&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-05-31 N1 - Date created - 2001-03-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Interindividual variance of cytochrome P450 forms in human hepatic microsomes: correlation of individual forms with xenobiotic metabolism and implications in risk assessment. AN - 72388961; 11067776 AB - Differences in biotransformation activities may alter the bioavailability or efficacy of drugs, provide protection from certain xenobiotic and environmental agents, or increase toxicity of others. Cytochrome P450 (CYP450) enzymes are responsible for the majority of oxidation reactions of drugs and other xenobiotics and differences in their expression may directly produce interindividual differences in susceptibility to compounds whose toxicity is modulated by these enzymes. To rapidly quantify CYP450 forms in human hepatic microsomes, we developed, and applied, an ELISA to 40 samples of microsomes from adult human organ donors. The procedure was reliable and the results were reproducible within normal limits. Protein content for CYP1A, CYP2E1, and CYP3A positively correlated with suitable marker activities. CYP1A, CYP2B, CYP2C6, CYP2C11, CYP2E1, and CYP3A protein content demonstrated 36-, 13-, 11-, 2-, 12-, and 22-fold differences between the highest and lowest samples and the values were normally distributed. Of the forms examined, CYP3A was expressed in the highest amount and it was the only form whose content was correlated with total CYP450 content. Content of other forms was independent of total CYP450. We further determined the contribution of specific forms to the biotransformation of trichloroethylene as a model substrate. CYP2E1 was strongly correlated with chloral hydrate formation from trichloroethylene; CYP2B displayed the strongest correlation with trichloroethanol formation. These data describing the expression and distribution of these forms in human microsomes can be used to extrapolate in vitro derived metabolic rates for toxicologically important reactions, when form selectivity and specific activity are known. This approach may be applied to refine estimates of human interindividual differences in susceptibility for application in human health risk assessment. JF - Regulatory toxicology and pharmacology : RTP AU - Snawder, J E AU - Lipscomb, J C AD - Taft Laboratory, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 200 EP - 209 VL - 32 IS - 2 SN - 0273-2300, 0273-2300 KW - Isoenzymes KW - 0 KW - Xenobiotics KW - Cytochrome P-450 Enzyme System KW - 9035-51-2 KW - Index Medicus KW - No-Observed-Adverse-Effect Level KW - Humans KW - Adult KW - Enzyme-Linked Immunosorbent Assay KW - Aged KW - Middle Aged KW - Male KW - Isoenzymes -- metabolism KW - Female KW - Risk Assessment KW - Cytochrome P-450 Enzyme System -- genetics KW - Xenobiotics -- metabolism KW - Microsomes, Liver -- enzymology KW - Genetic Variation -- physiology KW - Cytochrome P-450 Enzyme System -- metabolism KW - Cytochrome P-450 Enzyme System -- classification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72388961?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.atitle=Interindividual+variance+of+cytochrome+P450+forms+in+human+hepatic+microsomes%3A+correlation+of+individual+forms+with+xenobiotic+metabolism+and+implications+in+risk+assessment.&rft.au=Snawder%2C+J+E%3BLipscomb%2C+J+C&rft.aulast=Snawder&rft.aufirst=J&rft.date=2000-10-01&rft.volume=32&rft.issue=2&rft.spage=200&rft.isbn=&rft.btitle=&rft.title=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.issn=02732300&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-12-22 N1 - Date created - 2000-12-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A comparison of different postures for scaffold end-frame disassembly. AN - 72366269; 11059464 AB - Overexertion and fall injuries comprise the largest category of nonfatal injuries among scaffold workers. This study was conducted to identify the most favourable scaffold end-frame disassembly techniques and evaluate the associated slip potential by measuring whole-body isometric strength capability and required coefficient of friction (RCOF) to reduce the incidence of injury. Forty-six male construction workers were used to study seven typical postures associated with scaffold end-frame disassembly. An analysis of variance (ANOVA) showed that the isometric forces (334.4-676.3 N) resulting from the seven postures were significantly different (p < 0.05). Three of the disassembly postures resulted in considerable biomechanical stress to workers. The symmetric front-lift method with hand locations at knuckle height would be the most favourable posture; at least 93% of the male construction worker population could handle the end frame with minimum overexertion risk. The static RCOF value resulting from this posture during the disassembly phase was less than 0.2, thus the likelihood of a slip should be low. JF - Applied ergonomics AU - Cutlip, R AU - Hsiao, H AU - Garcia, R AU - Becker, E AU - Mayeux, B AD - National Institute for Occupational Safety and Health, Division of Safety Research, Morgantown, WV 26505, USA. rgc8@cdc.gov Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 507 EP - 513 VL - 31 IS - 5 SN - 0003-6870, 0003-6870 KW - Index Medicus KW - Anthropometry KW - Accidents, Occupational -- prevention & control KW - Isometric Contraction -- physiology KW - Analysis of Variance KW - Random Allocation KW - Humans KW - Linear Models KW - Adult KW - Accidental Falls -- prevention & control KW - Middle Aged KW - Adolescent KW - Muscles -- physiology KW - Male KW - Occupational Health -- statistics & numerical data KW - Posture -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72366269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+ergonomics&rft.atitle=A+comparison+of+different+postures+for+scaffold+end-frame+disassembly.&rft.au=Cutlip%2C+R%3BHsiao%2C+H%3BGarcia%2C+R%3BBecker%2C+E%3BMayeux%2C+B&rft.aulast=Cutlip&rft.aufirst=R&rft.date=2000-10-01&rft.volume=31&rft.issue=5&rft.spage=507&rft.isbn=&rft.btitle=&rft.title=Applied+ergonomics&rft.issn=00036870&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-08 N1 - Date created - 2001-02-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanate. AN - 72341650; 11035694 AB - Diisocyanates, a group of highly reactive chemicals, have frequently been associated with occupational asthma. We evaluated respiratory health in workers at a new wood products manufacturing plant that uses methylene diphenyl diisocyanate (MDI), and was designed and operated with a goal of minimizing worker exposures. Health surveys using standardized respiratory questionnaires were done prior to the initial use of diisocyanates in the plant, and semiannually thereafter for a period of 2 years. Other testing included occupational and work practice histories, serial peak flow measurements, spirometry, methacholine challenge, and measurement of specific IgE antibodies to MDI-albumin conjugate. Of 214 plant employees who participated in at least one health survey, a follow-up survey was also available from 178 employees (83%). New-onset asthma-like symptoms (NAS) were reported by 15 of 56 workers (27%) in areas with the highest potential for exposures to liquid MDI monomer and prepolymer, vs 0 of 43 workers in the lowest potential exposure areas (p = 0.001). In the areas with high potential exposure, NAS developed in 47% of workers who had noted MDI skin staining, vs 19% without skin stains (p = 0.07). Working around and cleaning up liquid MDI represented a significant risk for asthma-like symptoms in both current smokers and nonsmokers; work with finished wood products did not. Asthma-like symptoms were associated with variable airflow limitation (odds ratio [OR], 5.0; confidence interval [CI], 1.4 to 18.7) and specific IgE to MDI-albumin (OR, 3.2; CI, 1.1 to 9.0), but not with skin prick tests to common aeroallergens (OR, 1.1; CI, 0.5 to 2.7). During the first 2 years of operation, in a plant designed and operated to control exposure to diisocyanates, the development of asthma-like symptoms was reported in a relatively high proportion of the employees who worked with liquid MDI. To prevent asthma symptoms among workers, careful control of respiratory tract exposures associated with liquid MDI is important, especially during cleanup activities. Strict limitation of skin contact with diisocyanates may also be necessary. JF - Chest AU - Petsonk, E L AU - Wang, M L AU - Lewis, D M AU - Siegel, P D AU - Husberg, B J AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Morgantown, WV, USA. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 1183 EP - 1193 VL - 118 IS - 4 SN - 0012-3692, 0012-3692 KW - Air Pollutants, Occupational KW - 0 KW - Allergens KW - Isocyanates KW - 4,4'-diphenylmethane diisocyanate KW - 101-68-8 KW - Abridged Index Medicus KW - Index Medicus KW - Respiratory Function Tests KW - Odds Ratio KW - Diagnosis, Differential KW - Humans KW - Adult KW - Surveys and Questionnaires KW - Retrospective Studies KW - Confidence Intervals KW - United States -- epidemiology KW - Male KW - Female KW - Prevalence KW - Occupational Diseases -- diagnosis KW - Asthma -- epidemiology KW - Air Pollutants, Occupational -- adverse effects KW - Isocyanates -- adverse effects KW - Wood KW - Occupational Exposure -- adverse effects KW - Occupational Diseases -- epidemiology KW - Asthma -- diagnosis KW - Asthma -- chemically induced KW - Allergens -- adverse effects KW - Occupational Diseases -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72341650?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chest&rft.atitle=Asthma-like+symptoms+in+wood+product+plant+workers+exposed+to+methylene+diphenyl+diisocyanate.&rft.au=Petsonk%2C+E+L%3BWang%2C+M+L%3BLewis%2C+D+M%3BSiegel%2C+P+D%3BHusberg%2C+B+J&rft.aulast=Petsonk&rft.aufirst=E&rft.date=2000-10-01&rft.volume=118&rft.issue=4&rft.spage=1183&rft.isbn=&rft.btitle=&rft.title=Chest&rft.issn=00123692&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-15 N1 - Date created - 2000-11-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Methods to lower the dust exposure of bag machine operators and bag stackers. AN - 72336967; 11036726 AB - This article reviews various dust control technologies developed over the years at the Pittsburgh Research Laboratory of the National Institute for Occupational Safety and Health (NIOSH) to provide various options and alternatives to lower bag machine operators' and bag stackers' dust exposures. Dust exposure records for the past 20 years show that bag machine operators and bag stackers normally have the highest respirable dust exposures of workers at mineral processing plants. A substantial amount of research has been performed over the years to minimize the dust exposure to these workers and the intent is to present all this information together in one article. Most of the research describes engineering controls that were adapted to existing facilities to reduce the dust generated during bag filling, bag conveying, and bag stacking. In some cases, a single technique succeeded in lowering respirable dust concentrations for all three processes, thus reducing the dust exposure to both the bag machine operator and the bag stacker. In other cases, a technique was developed to specifically reduce the dust exposure of one process or the other. This research also reviews various controls for secondary dust exposure, including general ventilation requirements to mill buildings, the effects of background dust sources, and personal work practices. This information is presented to help industrial hygienists, plant managers, engineers, and workers lower the dust exposure of bag machine operators and bag stackers. JF - Applied occupational and environmental hygiene AU - Cecala, A B AU - Timko, R J AU - Thimons, E D AD - Pittsburgh Research Laboratory, National Institute for Occupational Safety and Health, Pennsylvania, USA. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 751 EP - 765 VL - 15 IS - 10 SN - 1047-322X, 1047-322X KW - Dust KW - 0 KW - Silicon Dioxide KW - 7631-86-9 KW - Index Medicus KW - United States KW - Equipment Design KW - Ventilation KW - Humans KW - National Institute for Occupational Safety and Health (U.S.) -- standards KW - Occupational Exposure -- prevention & control KW - Silicon Dioxide -- analysis KW - Occupational Exposure -- standards KW - Mining -- standards KW - Silicon Dioxide -- standards KW - Occupational Exposure -- analysis KW - Dust -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72336967?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+occupational+and+environmental+hygiene&rft.atitle=Methods+to+lower+the+dust+exposure+of+bag+machine+operators+and+bag+stackers.&rft.au=Cecala%2C+A+B%3BTimko%2C+R+J%3BThimons%2C+E+D&rft.aulast=Cecala&rft.aufirst=A&rft.date=2000-10-01&rft.volume=15&rft.issue=10&rft.spage=751&rft.isbn=&rft.btitle=&rft.title=Applied+occupational+and+environmental+hygiene&rft.issn=1047322X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-07 N1 - Date created - 2000-10-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Adverse drug reactions: a review of relevant factors. AN - 72322409; 11028248 AB - We examined some of the factors that contribute to the development of adverse drug reactions (ADRs) and analyzed postmarketing ADR reports for 22 drugs. The role of metabolic-based drug-drug interaction in the development of ADRs can not be overstated. Assessment of the postmarketing ADR data for 22 drugs revealed that drugs with high potential for eliciting clinically significant ADRs are usually detected and either withdrawn from the market or placed on restricted use within the first year or two of marketing. Postmarketing data could be a useful tool for understanding the ADR profile of drugs if reporting can be adequately monitored and verified. It is hoped that early evaluation of the clinically meaningful factors such as metabolism, pharmacogenetics, and effect of physiologic and pathophysiologic states on the clinical effect of a drug during drug development would significantly reduce the incidence and severity of post-marketing ADRs. JF - Journal of clinical pharmacology AU - Ajayi, F O AU - Sun, H AU - Perry, J AD - Office of Clinical Pharmacology & Biopharmaceutics, Food and Drug Administration, Rockville, Maryland 20857, USA. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 1093 EP - 1101 VL - 40 IS - 10 SN - 0091-2700, 0091-2700 KW - Pharmaceutical Preparations KW - 0 KW - Proteins KW - Index Medicus KW - Pharmaceutical Preparations -- metabolism KW - Risk Factors KW - Humans KW - Proteins -- metabolism KW - Genetic Heterogeneity KW - Adverse Drug Reaction Reporting Systems KW - Drug-Related Side Effects and Adverse Reactions KW - Product Surveillance, Postmarketing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72322409?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+clinical+pharmacology&rft.atitle=Adverse+drug+reactions%3A+a+review+of+relevant+factors.&rft.au=Ajayi%2C+F+O%3BSun%2C+H%3BPerry%2C+J&rft.aulast=Ajayi&rft.aufirst=F&rft.date=2000-10-01&rft.volume=40&rft.issue=10&rft.spage=1093&rft.isbn=&rft.btitle=&rft.title=Journal+of+clinical+pharmacology&rft.issn=00912700&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-01 N1 - Date created - 2001-01-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hemoglobin-based blood substitutes and the hazards of blood radicals. AN - 72316108; 11022843 AB - Cell-free hemoglobins, chemically altered or genetically expressed in microbial host systems, have been developed as oxygen-carrying therapeutics. Site-directed modifications are introduced and serve to stabilize the protein molecules in a tetrameric and/or a polymeric functional form. Animal studies, as well as recent clinical studies, have suggested these proteins probably deliver oxygen to tissues. However, concerns still persist regarding the interference of hemoglobin and its oxidation products with the vascular redox balance, potentially impeding its clinical usefulness. This article reviews our current understanding of heme-mediated toxicities and some of the emerging protective strategies used to overcome hemoglobin side reactions. JF - Free radical research AU - Alayash, A I AD - Laboratory of Plasma Derivatives, Center for Biologics Evaluation and Research, Food and Drug Administration, National Institutes of Health Campus, Bethesda, Maryland 20892, USA. alayash@cber.fda.gov Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 341 EP - 348 VL - 33 IS - 4 SN - 1071-5762, 1071-5762 KW - Blood Substitutes KW - 0 KW - Free Radicals KW - Hemoglobins KW - Recombinant Proteins KW - Solutions KW - Nitric Oxide KW - 31C4KY9ESH KW - Index Medicus KW - Oxidation-Reduction KW - Animals KW - Humans KW - Recombinant Proteins -- adverse effects KW - Nitric Oxide -- metabolism KW - Hemoglobins -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72316108?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Free+radical+research&rft.atitle=Hemoglobin-based+blood+substitutes+and+the+hazards+of+blood+radicals.&rft.au=Alayash%2C+A+I&rft.aulast=Alayash&rft.aufirst=A&rft.date=2000-10-01&rft.volume=33&rft.issue=4&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=Free+radical+research&rft.issn=10715762&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-01 N1 - Date created - 2001-01-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Infant immunization with acellular pertussis vaccines in the United States: assessment of the first two years' data from the Vaccine Adverse Event Reporting System (VAERS). AN - 72308346; 11015546 AB - To evaluate the safety of infant immunization with acellular pertussis vaccines in the United States. The US Food and Drug Administration approved the first acellular pertussis vaccine for use in infants in the United States on July 31, 1996. Adverse events in the United States after infant immunization with pertussis-containing vaccines, representing temporal (but not necessarily causal) associations between vaccinations and adverse events. Reports to the Vaccine Adverse Event Reporting System (VAERS), a passive national surveillance system. Reports concerning infant immunization against pertussis between January 1, 1995 (when whole-cell vaccine was in exclusive use) and June 30, 1998 (when acellular vaccine was in predominant use) were analyzed, if the reports were entered into the VAERS database by November 30, 1998. During the study, there were 285 reports involving death, 971 nonfatal serious reports, and 4514 less serious reports after immunization with any pertussis-containing vaccine. For 1995 there were 2071 reports; in 1996 there were 1894 reports; in 1997 there were 1314 reports, and in the first half of 1998 there were 491 reports. Diphtheria-tetanus-pertussis vaccine (DTP) was cited in 1939 reports, diphtheria-tetanus-whole-cell pertussis-Haemophilus influenzae type b vaccine (DTPH) in 2918 reports, and diphtheria-tetanus-acellular pertussis vaccine (DTaP) in 913 reports. The annual number of deaths during the study was 85 in 1995, 82 in 1996, 77 in 1997, and 41 in the first half of 1998. The annual number of reported events categorized as nonfatal serious (defined as events involving initial hospitalization, prolongation of hospitalization, life-threatening illness, or permanent disability) to VAERS for all pertussis-containing vaccines declined: 334 in 1995, 311 in 1996, 233 in 1997, and 93 in the first half of 1998. Similarly, the annual number of less serious reports to VAERS for pertussis-containing vaccines declined: 1652 in 1995, 1501 in 1996, 1004 in 1997, and 357 in the first half of 1998. A comparison of the adverse event profiles (proportional distributions) for DTaP, DTP, and DTPH, as well as an analysis of specific adverse events considered in a 1991 Institute of Medicine report on the safety of diphtheria-tetanus-pertussis vaccine, did not identify any new, clear safety concerns. These findings reflect the administration of millions of doses of acellular pertussis vaccine and are reassuring with regard to the safety of marketed acellular pertussis vaccines. VAERS data, although subject to the limitations of passive surveillance, support the prelicensure data with regard to the safety of the US-licensed acellular pertussis vaccines that we evaluated. JF - Pediatrics AU - Braun, M M AU - Mootrey, G T AU - Salive, M E AU - Chen, R T AU - Ellenberg, S S AD - Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20852, USA. braunm@cber.fda.gov Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 1 VL - 106 IS - 4 KW - Diphtheria-Tetanus-Pertussis Vaccine KW - 0 KW - Diphtheria-Tetanus-acellular Pertussis Vaccines KW - Haemophilus Vaccines KW - Pertussis Vaccine KW - Vaccines, Acellular KW - diphtheria-tetanus-pertussis-haemophilus b conjugate vaccine KW - Index Medicus KW - Vaccines, Acellular -- adverse effects KW - Humans KW - Birth Rate KW - Diphtheria-Tetanus-Pertussis Vaccine -- adverse effects KW - Infant Mortality KW - Haemophilus Vaccines -- adverse effects KW - Cause of Death KW - Population Surveillance KW - Central Nervous System Diseases -- chemically induced KW - Infant KW - United States Food and Drug Administration KW - Diphtheria-Tetanus-acellular Pertussis Vaccines -- adverse effects KW - Adverse Drug Reaction Reporting Systems KW - United States -- epidemiology KW - Pertussis Vaccine -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72308346?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatrics&rft.atitle=Infant+immunization+with+acellular+pertussis+vaccines+in+the+United+States%3A+assessment+of+the+first+two+years%27+data+from+the+Vaccine+Adverse+Event+Reporting+System+%28VAERS%29.&rft.au=Braun%2C+M+M%3BMootrey%2C+G+T%3BSalive%2C+M+E%3BChen%2C+R+T%3BEllenberg%2C+S+S&rft.aulast=Braun&rft.aufirst=M&rft.date=2000-10-01&rft.volume=106&rft.issue=4&rft.spage=E51&rft.isbn=&rft.btitle=&rft.title=Pediatrics&rft.issn=1098-4275&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-31 N1 - Date created - 2000-10-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hypotonic-hyporesponsive episodes reported to the Vaccine Adverse Event Reporting System (VAERS), 1996-1998. AN - 72306281; 11015547 AB - A hypotonic-hyporesponsive episode (HHE) is the sudden onset of hypotonia, hyporesponsiveness, and pallor or cyanosis that occurs within 48 hours after childhood immunizations. This syndrome has been primarily associated with pertussis-containing vaccines administered to children <2 years of age, and has been estimated to occur once every 1750 diphtheria-tetanus-pertussis (DTwP) vaccinations. Previous studies of HHE were limited by small numbers of cases and, sometimes, by limited details of the event. To characterize a large number of HHE cases reported to the Vaccine Adverse Event Reporting System (VAERS), to assist clinicians in identifying HHE, and to assist researchers in investigating the risk factors, cause, and pathogenesis of this syndrome. More than 40,000 VAERS reports received between 1996 and 1998 were screened for HHE by a computer algorithm and reviewed, and a telephone follow-up questionnaire was administered to the witness of HHE. There were 215 HHE cases, all nonfatal. The median age of onset of HHE was 4.0 months (range: 1.1-107 months). Over half of the reports (53%) concerned females. The median birth weight was 3. 36 kg (range: 1.27-4.96 kg); 4.7% had a birth weight 24 months of age. There were no relevant findings regarding family medical history or the mothers' gestational history. Nearly all of the children (98.6%) returned to their prevaccination state according to the telephone questionnaire; median time to return was 6 hours (range: 1 minute- 4 months). The 3 children reported as not returning to their prevaccination state all had VAERS reports submitted after they developed conditions (autism, complex partial epilepsy, and developmental delays with infantile spasms) that are not known to be causally associated with immunization. The vast majority of children (93%) with HHE received a pertussis-containing vaccine, either diphtheria-tetanus-acellular pertussis (DTaP, 28%), DTwP (11%), or diphtheria-tetanus-pertussis-Haemophilus influenzae type b (DTwP-HIB, 61%). During the HHE episode, 90.1% of the children had pallor and 49% had cyanosis. Because of the HHE event, 6.8% of children had had all vaccines withheld as of the date of the interview. Of the remainder, 66.5% of children have had 1 or more subsequent vaccinations or vaccine components withheld, and 26.7% have not had any subsequent vaccinations withheld. Only 1 child was reported to have had a repeat episode of HHE, occurring after hepatitis B vaccination. From 1996 to 1998, the number of HHE reports decreased from 99 to 38, when the predominant pertussis vaccine administered to infants changed from whole-cell to acellular. This study represents the largest published case series of children with HHE and supports the generally benign, self-limited, nonrecurrent nature of this syndrome. Although HHE has been less frequently reported to VAERS after increased use of DTaP, HHE does occur after the administration of DTaP and other nonpertussis-containing vaccines. Although most parents and pediatricians withheld the pertussis component of subsequent vaccinations, many did not, with no reported adverse events occurring in the children after the subsequent immunizations. Restricting the definition of HHE to a more narrow age range (eg, <2 years of age) is also proposed because most of the older children probably experienced vasovagal syncope rather than HHE within 5 minutes of immunization. JF - Pediatrics AU - DuVernoy, T S AU - Braun, M M AD - Division of Epidemiology, Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20852-1428, USA. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 1 VL - 106 IS - 4 KW - Pertussis Vaccine KW - 0 KW - Vaccines, Acellular KW - Vaccines, Combined KW - Viral Vaccines KW - Index Medicus KW - United States KW - Infant KW - Vaccines, Acellular -- adverse effects KW - Cyanosis -- chemically induced KW - Adverse Drug Reaction Reporting Systems KW - Vaccines, Combined -- adverse effects KW - Humans KW - Surveys and Questionnaires KW - Child KW - Male KW - Female KW - Child, Preschool KW - Pertussis Vaccine -- adverse effects KW - Viral Vaccines -- adverse effects KW - Muscle Hypotonia -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72306281?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatrics&rft.atitle=Hypotonic-hyporesponsive+episodes+reported+to+the+Vaccine+Adverse+Event+Reporting+System+%28VAERS%29%2C+1996-1998.&rft.au=DuVernoy%2C+T+S%3BBraun%2C+M+M&rft.aulast=DuVernoy&rft.aufirst=T&rft.date=2000-10-01&rft.volume=106&rft.issue=4&rft.spage=E52&rft.isbn=&rft.btitle=&rft.title=Pediatrics&rft.issn=1098-4275&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-31 N1 - Date created - 2000-10-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Improved template preparation for PCR-based assays for detection of food-borne bacterial pathogens. AN - 72297697; 11010913 AB - Shigella flexneri, Salmonella enterica serotype Typhimurium, and Listeria monocytogenes were applied to FTA filters, and the filters were used directly as templates to demonstrate their sensitivity and applicability in PCR-based detection assays. With pure cultures, the sensitivities of detection by FTA filter-based PCR were 30 to 50 and 200 CFU for the gram-negative enterics and Listeria, respectively. Different numbers of S. flexneri cells were used in controlled contamination experiments with several different foods (produce, beef, and apple cider). Aliquots from concentrated food washes subsequently spotted onto FTA filters and assayed by PCR gave consistently positive results and detection limits similar to those observed with pure-culture dilutions. This universal method for PCR template preparation from bacterial cells is rapid and highly sensitive and reduces interference from food-associated inhibitors of PCR. In addition, its broad applicability eliminates the need for multiple methods for analysis of food matrices. JF - Applied and environmental microbiology AU - Lampel, K A AU - Orlandi, P A AU - Kornegay, L AD - Center for Food Safety and Applied Nutrition, Food and Drug Administration, Washington, D.C. 20204, USA. kal@codon.nih.gov Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 4539 EP - 4542 VL - 66 IS - 10 SN - 0099-2240, 0099-2240 KW - Index Medicus KW - Sensitivity and Specificity KW - Animals KW - Cattle KW - Fruit -- microbiology KW - Beverages -- microbiology KW - Meat -- microbiology KW - Templates, Genetic KW - Listeria monocytogenes -- isolation & purification KW - Listeria monocytogenes -- genetics KW - Food Microbiology KW - Shigella flexneri -- isolation & purification KW - Polymerase Chain Reaction -- methods KW - Polymerase Chain Reaction -- instrumentation KW - Shigella flexneri -- genetics KW - Salmonella typhimurium -- isolation & purification KW - Salmonella typhimurium -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72297697?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Improved+template+preparation+for+PCR-based+assays+for+detection+of+food-borne+bacterial+pathogens.&rft.au=Lampel%2C+K+A%3BOrlandi%2C+P+A%3BKornegay%2C+L&rft.aulast=Lampel&rft.aufirst=K&rft.date=2000-10-01&rft.volume=66&rft.issue=10&rft.spage=4539&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-30 N1 - Date created - 2000-10-17 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Biotechniques. 2000 Feb;28(2):346-50 [10683746] Emerg Infect Dis. 1999 Sep-Oct;5(5):626-34 [10511518] J Infect Dis. 1989 Jun;159(6):1126-8 [2656880] J Bacteriol. 1990 Apr;172(4):1905-15 [1690703] Lett Appl Microbiol. 1990 Jan;10(1):23-6 [1366573] Mol Cell Probes. 1990 Oct;4(5):353-65 [2280781] J Appl Bacteriol. 1991 May;70(5):372-9 [1908450] Appl Environ Microbiol. 1991 Dec;57(12):3529-34 [1785928] Adv Clin Chem. 1992;29:161-96 [1585849] J Bacteriol. 1992 Jul;174(13):4338-49 [1624429] Appl Environ Microbiol. 1993 May;59(5):1289-93 [8517730] Lett Appl Microbiol. 1994 Nov;19(5):294-8 [7765440] Biotechniques. 1995 Sep;19(3):426-32 [7495556] Anal Biochem. 1997 May 1;247(2):223-7 [9177681] J Appl Microbiol. 1997 Dec;83(6):727-36 [9449811] Mol Cell Probes. 1998 Apr;12(2):79-83 [9633042] Emerg Infect Dis. 1999 Sep-Oct;5(5):607-25 [10511517] J Clin Microbiol. 2000 Jun;38(6):2271-7 [10834988] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Interactions of hemoglobin with hydrogen peroxide alters thiol levels and course of endothelial cell death. AN - 72296929; 11009476 AB - We investigated cellular injury and death induced by ultrapure human Hb (HbA(0)) and its diaspirin cross-linked derivative DBBF-Hb in normal and glutathione (GSH)-depleted bovine aortic endothelial cells subjected to hydrogen peroxide (H(2)O(2)). HbA(0) underwent extensive degradation and heme loss, whereas DBBF-Hb persisted longer in its ferryl (Fe(4+)) form. The formation of ferryl HbA(0) or ferryl DBBF-Hb was associated with a significant decrease in endothelial cell GSH compared with the addition of H(2)O(2) or Hbs alone. This effect was inhibited by catalase, but not by superoxide dismutase or deferoxamine mesylate. The presence of HbA(0) and DBBF-Hb reduced H(2)O(2)-induced apoptosis, as measured by cell morphology, annexin V binding assay, and caspase inhibition, consistent with the ability to consume H(2)O(2) in an enzyme-like fashion. However, the pattern of cell death and injury produced by HbA(0) and DBBF-Hb appeared to be distinctly different among proteins as well as among cells with and without GSH. These findings may have important implications for the use of cell-free Hb as oxygen therapeutics in patients with coexisting pathologies who may lack antioxidant protective mechanisms. JF - American journal of physiology. Heart and circulatory physiology AU - D'Agnillo, F AU - Alayash, A I AD - Laboratory of Plasma Derivatives, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - H1880 EP - H1889 VL - 279 IS - 4 SN - 0363-6135, 0363-6135 KW - Annexin A5 KW - 0 KW - Hemoglobins KW - Oxidants KW - Sulfhydryl Compounds KW - bis(3,5-dibromosalicyl)sebacate-crosslinked hemoglobin KW - Heme KW - 42VZT0U6YR KW - hemoglobin A(0) KW - 54651-57-9 KW - Hemoglobin A KW - 9034-51-9 KW - Hydrogen Peroxide KW - BBX060AN9V KW - Glutathione KW - GAN16C9B8O KW - Aspirin KW - R16CO5Y76E KW - Index Medicus KW - Aorta -- metabolism KW - Animals KW - Aorta -- physiology KW - Humans KW - Glutathione -- metabolism KW - Hemoglobins -- pharmacology KW - Annexin A5 -- metabolism KW - Cell Death -- drug effects KW - Cattle KW - Aorta -- drug effects KW - Cells, Cultured KW - Apoptosis -- drug effects KW - Aorta -- cytology KW - Heme -- metabolism KW - Endothelium, Vascular -- metabolism KW - Endothelium, Vascular -- drug effects KW - Sulfhydryl Compounds -- metabolism KW - Oxidants -- pharmacology KW - Endothelium, Vascular -- cytology KW - Aspirin -- analogs & derivatives KW - Hydrogen Peroxide -- pharmacology KW - Hemoglobin A -- pharmacology KW - Aspirin -- pharmacology KW - Endothelium, Vascular -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72296929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+physiology.+Heart+and+circulatory+physiology&rft.atitle=Interactions+of+hemoglobin+with+hydrogen+peroxide+alters+thiol+levels+and+course+of+endothelial+cell+death.&rft.au=D%27Agnillo%2C+F%3BAlayash%2C+A+I&rft.aulast=D%27Agnillo&rft.aufirst=F&rft.date=2000-10-01&rft.volume=279&rft.issue=4&rft.spage=H1880&rft.isbn=&rft.btitle=&rft.title=American+journal+of+physiology.+Heart+and+circulatory+physiology&rft.issn=03636135&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-07 N1 - Date created - 2000-10-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Historical respirable quartz exposures of industrial sand workers: 1946-1996. AN - 72252805; 10982979 AB - Besides a clear relationship to silicosis, crystalline silica-quartz-has been associated with lung cancer, nonmalignant renal disease, and auto-immune disease. To study diseases associated with crystalline silica further, NIOSH conducted a cohort mortality study of workers from 18 silica sand plants, which had quarry, crushing, and bagging operations to produce industrial sand. Twelve of these plants also had grinding mills to produce fine silica powder. The historical crystalline silica exposures of workers at these plants were estimated to facilitate exposure-response analyses in the epidemiologic study. NIOSH obtained personal respirable dust measurement records from Mine Safety and Health Administration (MSHA) compliance inspections at all 18 plants and from the archives of seven plants which had collected samples. These samples had been analyzed for quartz content by x-ray diffraction. Although no personal samples were available before 1974, impinger dust measurements were reported for 19 silica sand plants in 1946; these data were converted and used to estimate exposures prior to 1974. Statistical modeling of the samples was used to estimate quartz exposure concentrations for workers in plant-job-year categories from the 1930s when mortality follow-up of the cohort began until 1988 when follow-up stopped. Between 1974 and 1996, there were 4,269 respirable dust samples collected at these 18 plants. The geometric mean quartz concentration was 25.9 microg/m(3) (GSD = 10.9) with a range from less than 1 to 11,700 microg/m(3). Samples below 1 microg/m(3) were given a value of 0.5 microg/m(3). Over one-third of the samples -37%) exceeded the MSHA permissible exposure limit value for quartz (PEL = 10 mg/m(3)/(%quartz + 2)) and half (51%) of the samples exceeded the NIOSH recommended exposure limit (REL=50 microg/m(3)). The samples were collected from workers performing 143 jobs within the 18 plants, but too few samples were collected from many of the jobs to make accurate estimates. Therefore, samples were combined into 10 categories of jobs performing similar tasks or located within the same plant area. The quartz concentrations varied significantly by plant, job, and year. Quartz concentrations decreased over time, with measurements collected in the 1970s significantly greater than those collected later. The modeled exposure estimates improve upon duration of employment as an estimate of cumulative exposure and reduce exposure misclassification due to variation in quartz levels between plants, jobs, and over time. Am. J. Ind. Med. 38:389-398, 2000. Published 2000 Wiley-Liss, Inc. JF - American journal of industrial medicine AU - Sanderson, W T AU - Steenland, K AU - Deddens, J A AD - Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226-1998, USA. wts1@cdc.gov Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 389 EP - 398 VL - 38 IS - 4 SN - 0271-3586, 0271-3586 KW - Quartz KW - 14808-60-7 KW - Index Medicus KW - United States KW - Humans KW - Occupational Exposure KW - Mining UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72252805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+industrial+medicine&rft.atitle=Historical+respirable+quartz+exposures+of+industrial+sand+workers%3A+1946-1996.&rft.au=Sanderson%2C+W+T%3BSteenland%2C+K%3BDeddens%2C+J+A&rft.aulast=Sanderson&rft.aufirst=W&rft.date=2000-10-01&rft.volume=38&rft.issue=4&rft.spage=389&rft.isbn=&rft.btitle=&rft.title=American+journal+of+industrial+medicine&rft.issn=02713586&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-18 N1 - Date created - 2000-10-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A comparison of the inflammatory response to a polydimethylsiloxane implant in male and female Balb/c mice. AN - 71766682; 10941916 AB - The implantation of biomaterials elicits a host response that influences the long-term behavior of implanted medical devices. This foreign body response is governed by cells of the immune system. Because sexual dimorphism in the immune system is well-established, a comparative study of the foreign body response in male and female mice was initiated. Eight-week-old male and female Balb/c mice received two subcutaneous implants in the interscapular region of a smooth peroxide-catalyzed polydimethylsiloxane (PDMS) and were sacrificed at 2, 14, 42, 70, and 105 days after implantation (n = 6 per sex per time point). Controls for each time point underwent the surgical procedure but received no implant. Tissue from the implant or surgical site was fixed, processed, and paraffin-embedded for histopathological evaluation and immunohistochemical (IHC) staining for tumor necrosis factor-alpha TNF-alpha) and interleukin-1 beta (IL-1beta). In control animals, an inflammatory response was observed at 2 days that was decreased by 14 days and absent after 42 days. At 2 and 14 days after PDMS implantation, a mild to moderate inflammatory reaction was observed around implants. The peak response was seen at 14 days, and granulation tissue, composed primarily of fibroblasts, macrophages, and neutrophils, was first observed at this time. After 105 days, the implantation site was surrounded by mature connective tissue, which had minimal numbers of macrophages and neutrophils, with severity scores that did not differ significantly in males and females. The immunostaining for TNF-alpha and IL-1beta followed similar temporal patterns, with both reaching a peak at the two week time point and remaining elevated, compared to level of expression in the controls, throughout the 105 day observation period. Staining for both cytokines in the implanted animals was generally higher in females than in males, although this difference was significant only for IL-1beta. These results suggest subtle differences between males and females in the activity of peri-implant inflammatory cells. JF - Biomaterials AU - Dalu, A AU - Blaydes, B S AU - Lomax, L G AU - Delclos, K B AD - Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 1947 EP - 1957 VL - 21 IS - 19 SN - 0142-9612, 0142-9612 KW - Coated Materials, Biocompatible KW - 0 KW - Dimethylpolysiloxanes KW - Interleukin-1 KW - Silicones KW - Tumor Necrosis Factor-alpha KW - baysilon KW - 63148-62-9 KW - Index Medicus KW - Animals KW - Sex Characteristics KW - Tumor Necrosis Factor-alpha -- analysis KW - Mice KW - Interleukin-1 -- analysis KW - Mice, Inbred BALB C KW - Time Factors KW - Male KW - Female KW - Dimethylpolysiloxanes -- toxicity KW - Silicones -- toxicity KW - Coated Materials, Biocompatible -- toxicity KW - Inflammation -- etiology KW - Prostheses and Implants -- adverse effects KW - Inflammation -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71766682?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biomaterials&rft.atitle=A+comparison+of+the+inflammatory+response+to+a+polydimethylsiloxane+implant+in+male+and+female+Balb%2Fc+mice.&rft.au=Dalu%2C+A%3BBlaydes%2C+B+S%3BLomax%2C+L+G%3BDelclos%2C+K+B&rft.aulast=Dalu&rft.aufirst=A&rft.date=2000-10-01&rft.volume=21&rft.issue=19&rft.spage=1947&rft.isbn=&rft.btitle=&rft.title=Biomaterials&rft.issn=01429612&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-28 N1 - Date created - 2000-11-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Fundamentals of coal mine roof support AN - 52038018; 2003-003071 AB - Roof supports can only be understood in conjunction with the rock structure that they support. The strength of the rock depends on geology, and the loads are applied primarily by the in situ and mining-induced stresses. Other factors, such as wider spans and retreat or multiple-seam mining, can also reduce the stability of mine openings. Roof supports are used to help stabilize these openings, but their performance characteristics must be properly matched to the loading environment and ground behavior if they are to succeed. Roof supports include both intrinsic supports, such as roof bolts, and standing supports. The key characteristics of any support include its maximum load-carrying capacity, stiffness, and residual strength. Other important factors are the timing of installation, the stability of the support as it is loaded, and the capability of the support system to provide skin control. This paper explains in practical terms how supports work and the important factors in ensuring that a good support design and application strategy are developed. JF - Information Circular - National Institute for Occupational Safety and Health AU - Mark, Christopher AU - Barczak, Thomas M A2 - Mark, Christopher A2 - Dolinar, Dennis R. A2 - Tuckman, Robert J. A2 - Barczak, Thomas M. A2 - Signer, Stephen P. A2 - Wopat, Priscilla F. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 23 EP - 42 PB - National Institute for Occupational Safety and Health, Pittsburgh, PA KW - mines KW - roof control KW - mining geology KW - stress KW - stiffness KW - coal mines KW - stability KW - pillars KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52038018?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.atitle=Fundamentals+of+coal+mine+roof+support&rft.au=Mark%2C+Christopher%3BBarczak%2C+Thomas+M&rft.aulast=Mark&rft.aufirst=Christopher&rft.date=2000-10-01&rft.volume=&rft.issue=&rft.spage=23&rft.isbn=&rft.btitle=&rft.title=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2003-01-01 N1 - Number of references - 29 N1 - PubXState - PA N1 - Document feature - illus. incl. sketch map N1 - Last updated - 2012-06-07 N1 - CODEN - #04567 N1 - SubjectsTermNotLitGenreText - coal mines; mines; mining geology; pillars; roof control; stability; stiffness; stress ER - TY - JOUR T1 - Proceedings; New technology for coal mine roof support AN - 52035557; 2003-003070 JF - Information Circular - National Institute for Occupational Safety and Health A2 - Mark, Christopher A2 - Dolinar, Dennis R. A2 - Tuckman, Robert J. A2 - Barczak, Thomas M. A2 - Signer, Stephen P. A2 - Wopat, Priscilla F. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 280 PB - National Institute for Occupational Safety and Health, Pittsburgh, PA KW - engineering geology KW - technology KW - roof control KW - mining geology KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52035557?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2000-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Proceedings%3B+New+technology+for+coal+mine+roof+support&rft.title=Proceedings%3B+New+technology+for+coal+mine+roof+support&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2003-01-01 N1 - PubXState - PA N1 - SuppNotes - Individual paper within scope are cited separately N1 - Last updated - 2012-06-07 N1 - CODEN - #04567 N1 - SubjectsTermNotLitGenreText - engineering geology; mining geology; roof control; technology ER - TY - JOUR T1 - Summary of field measurements of roof bolt performance AN - 52034916; 2003-003073 AB - During the 1990s, the former U.S. Bureau of Mines conducted a number of field studies in which the performance of different types of roof bolts were evaluated in different geologic environments. The studies used a standard suite of measurements, including multipoint extensometers, strain-gauged roof bolts, and roof bolt load cells. The sites were chosen to investigate the effect of a variety of parameters, including installed tension, bolt capacity, grout annulus, and horizontal stress orientation. Although not fully successful, the measurements provided valuable insights into each of these issues. They also showed that instrumentation and monitoring have important advantages over observational methods for comparing the performance of different roof bolting systems. JF - Information Circular - National Institute for Occupational Safety and Health AU - Mark, Christopher AU - Dolinar, Dennis R AU - Mucho, Thomas P A2 - Mark, Christopher A2 - Dolinar, Dennis R. A2 - Tuckman, Robert J. A2 - Barczak, Thomas M. A2 - Signer, Stephen P. A2 - Wopat, Priscilla F. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 81 EP - 98 PB - National Institute for Occupational Safety and Health, Pittsburgh, PA KW - United States KW - mining KW - mines KW - underground mining KW - roof control KW - stress KW - coal mines KW - extensometers KW - Harlan County Kentucky KW - Cambria County Pennsylvania KW - bolts KW - longwall mining KW - mining geology KW - Greene County Pennsylvania KW - Kentucky KW - Pennsylvania KW - pillars KW - field studies KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52034916?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.atitle=Summary+of+field+measurements+of+roof+bolt+performance&rft.au=Mark%2C+Christopher%3BDolinar%2C+Dennis+R%3BMucho%2C+Thomas+P&rft.aulast=Mark&rft.aufirst=Christopher&rft.date=2000-10-01&rft.volume=&rft.issue=&rft.spage=81&rft.isbn=&rft.btitle=&rft.title=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2003-01-01 N1 - Number of references - 14 N1 - PubXState - PA N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - CODEN - #04567 N1 - SubjectsTermNotLitGenreText - bolts; Cambria County Pennsylvania; coal mines; extensometers; field studies; Greene County Pennsylvania; Harlan County Kentucky; Kentucky; longwall mining; mines; mining; mining geology; Pennsylvania; pillars; roof control; stress; underground mining; United States ER - TY - JOUR T1 - Skin failure of roof and rib and support techniques in underground coal mines AN - 52034604; 2003-003074 AB - Skin failures of roof and rib in underground coal mines continue to be a significant safety hazard for mine workers. Skin failures do not usually involve failure of the support systems, but result from rock or coal spalling from between the support elements. For instance, in 1997 more than 800 miners were injured by roof and rib falls, of which 98% were the result of skin failures [Bauer et al. 1999]. Also, nearly 80% of the roof and rib failure injuries occurred at or near the working faces in development sections. The face area is a zone where the potential for skin failure accidents and injuries and for roof and rib failures is high because of mining activity, ground readjustment due to changing stress conditions, and the higher exposure of mine workers. In addition, failures occur where the roof and rib are unsupported. This paper reviews the roof and rib accident statistics resulting from skin failure, and highlights the incidences by type, numbers and percentage, in-mine location, supported and unsupported roof, and worker activity at the time of injury. Also discussed are the causes of roof and rib skin failures, current and improved support methods and materials for skin surface control, and machine design modifications for improved roof bolter operator protection. It also reviews the historical literature on skin failures and control methods. JF - Information Circular - National Institute for Occupational Safety and Health AU - Bauer, Eric R AU - Dolinar, Dennis R A2 - Mark, Christopher A2 - Dolinar, Dennis R. A2 - Tuckman, Robert J. A2 - Barczak, Thomas M. A2 - Signer, Stephen P. A2 - Wopat, Priscilla F. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 99 EP - 109 PB - National Institute for Occupational Safety and Health, Pittsburgh, PA KW - spalling KW - mining KW - mines KW - failures KW - discontinuities KW - underground mining KW - roof control KW - moisture KW - mining geology KW - stress KW - coal mines KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52034604?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.atitle=Skin+failure+of+roof+and+rib+and+support+techniques+in+underground+coal+mines&rft.au=Bauer%2C+Eric+R%3BDolinar%2C+Dennis+R&rft.aulast=Bauer&rft.aufirst=Eric&rft.date=2000-10-01&rft.volume=&rft.issue=&rft.spage=99&rft.isbn=&rft.btitle=&rft.title=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2003-01-01 N1 - Number of references - 22 N1 - PubXState - PA N1 - Document feature - illus. incl. 4 tables N1 - Last updated - 2012-06-07 N1 - CODEN - #04567 N1 - SubjectsTermNotLitGenreText - coal mines; discontinuities; failures; mines; mining; mining geology; moisture; roof control; spalling; stress; underground mining ER - TY - JOUR T1 - Load behavior of grouted bolts in sedimentary rock AN - 52034446; 2003-003072 AB - This paper presents an overview of laboratory and field tests on approximately 250 fully grouted roof bolts instrumented with strain gauges in order to study loading behavior. Laboratory work included pull tests, time-dependent tests, and shear tests. The field tests were conducted in 14 different mines extracting different commodities. However, because of the focus of this publication, only the results of tests in 9 coal mines are reported here. In the field tests, all but 14 bolts were loaded by rock movement; these 14 bolts were tested using pull gear. The variables studied included anchorage length, mechanical interlock, time-dependent behavior, shear, installation load, loading rate, and maximum load level. Such information will improve the understanding of the behavior of resin-grouted bolts, which in return will enhance the safety of miners by reducing the occurrence of rock falls. The influences of geology, overburden depth, entry width, mining-induced stresses, and bolt spacing are not described. JF - Information Circular - National Institute for Occupational Safety and Health AU - Signer, Stephen P A2 - Mark, Christopher A2 - Dolinar, Dennis R. A2 - Tuckman, Robert J. A2 - Barczak, Thomas M. A2 - Signer, Stephen P. A2 - Wopat, Priscilla F. Y1 - 2000/10// PY - 2000 DA - October 2000 SP - 73 EP - 80 PB - National Institute for Occupational Safety and Health, Pittsburgh, PA KW - mines KW - laboratory studies KW - failures KW - sedimentary rocks KW - mining geology KW - loading KW - behavior KW - coal mines KW - shear tests KW - grouting KW - field studies KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52034446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.atitle=Load+behavior+of+grouted+bolts+in+sedimentary+rock&rft.au=Signer%2C+Stephen+P&rft.aulast=Signer&rft.aufirst=Stephen&rft.date=2000-10-01&rft.volume=&rft.issue=&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Information+Circular+-+National+Institute+for+Occupational+Safety+and+Health&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2003-01-01 N1 - Number of references - 10 N1 - PubXState - PA N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - CODEN - #04567 N1 - SubjectsTermNotLitGenreText - behavior; coal mines; failures; field studies; grouting; laboratory studies; loading; mines; mining geology; sedimentary rocks; shear tests ER - TY - JOUR T1 - Prevalence of Rupture of Silicone Gel Breast Implants Revealed on MR Imaging in a Population of Women in Birmingham, Alabama AN - 20675111; 9432735 AB - OBJECTIVE. Silicone gel breast implants have been reported to rupture, but the prevalence of implant rupture in an unreferred population of women is not known. The objective of this study was to assess the prevalence of implant rupture and the presence of extracapsular silicone gel in an unreferred population of women without regard to the absence or presence of any local or systemic symptoms. SUBJECTS AND METHODS. Women identified as part of a National Cancer Institute cohort study on breast implants, living in the Birmingham, AL, area were invited to undergo MR imaging of their current silicone gel breast implants at the Kirklin Clinic at the University of Alabama at Birmingham. Three radiologists independently examined and rated all MR images for signs of implant rupture and extracapsular silicone. RESULTS. A total of 344 women with silicone gel breast implants underwent MR imaging. Breast implant rupture was reported by at least two of three radiologists for 378 (55.0%) of the 687 implants in this study. Another 50 implants (7.2%) were rated as indeterminate (suspicious) for rupture. A majority of women in this study, 265 (77.0%) of 344, had at least one breast implant that was rated as ruptured or indeterminate. Radiologists also agreed that silicone gel could be seen outside the fibrous capsule that forms around the implant in 85 (12.4%) of the 687 implants affecting 73 women (21.2%). Factors that affected implant rupture were implant age and location (submuscular or subglandular). The median implant age at rupture was estimated to be 10.8 years with a 95% confidence interval of 8.4-13.9 years. CONCLUSION. The prevalence of silent or occult silicone gel breast implant rupture is higher than was previously suspected. Most women in this study had MR imaging evidence of at least one ruptured silicone gel breast implant. JF - American Journal of Roentgenology AU - Brown, S L AU - Middleton AU - Berg, WA AU - Soo AU - Pennello, G AD - Office of Surveillance and Biometrics, Center for Devices and Radiological Health, Food and Drug Administration, 1350 Piccard Dr., HFZ-541, Rockville, MD 20850, USA Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 1057 EP - 1064 VL - 175 IS - 4 SN - 0361-803X, 0361-803X KW - Biotechnology and Bioengineering Abstracts KW - Age KW - Silicones KW - Magnetic resonance imaging KW - Computed tomography KW - Rupture KW - W 30910:Imaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20675111?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Roentgenology&rft.atitle=Prevalence+of+Rupture+of+Silicone+Gel+Breast+Implants+Revealed+on+MR+Imaging+in+a+Population+of+Women+in+Birmingham%2C+Alabama&rft.au=Brown%2C+S+L%3BMiddleton%3BBerg%2C+WA%3BSoo%3BPennello%2C+G&rft.aulast=Brown&rft.aufirst=S&rft.date=2000-10-01&rft.volume=175&rft.issue=4&rft.spage=1057&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Roentgenology&rft.issn=0361803X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Age; Silicones; Computed tomography; Magnetic resonance imaging; Rupture ER - TY - JOUR T1 - Differentiation between Types and Strains of Clostridium botulinum by Riboprinting AN - 18387355; 5382091 AB - The ability of automated ribotyping to differentiate between major types and individual strains of Clostridium botulinum was tested using the Qualicon Riboprinter Microbial Characterization System. Pure spores of C. botulinum type A, proteolytic type B, nonproteolytic type B, and type E strains were inoculated onto modified anaerobic egg yolk agar and incubated 24 h at 35 degree C. Plates were rinsed with buffer (2 mM Tris + 20 mM EDTA) to remove vegetative cells that were heated for 10 min at 80 degree C, treated with a lysing agent, and ribotyped in the Qualicon Riboprinter utilizing the enzyme EcoRI. Riboprint patterns were obtained for 30 strains of the four major types of C. botulinum most commonly involved in human foodborne botulism. Proteolytic strains yielded the best and most consistent results. Fifteen ribogroups were identified among the 31 strains tested. Interestingly, in two cases, a single ribogroup contained patterns from isolates belonging to evolutionarily distinct Clostridium lineages. This degree of differentiation between strains of C. botulinum may be useful in hazard analysis and identification, hazard analysis and critical control point monitoring and validation, environmental monitoring, and in inoculation studies. JF - Journal of Food Protection AU - Skinner, GE AU - Gendel, S M AU - Fingerhut, G A AU - Ulaszek, J AU - Solomon, HA AD - U.S. Food and Drug Administration, National Center for Food Safety and Technology, 6502 South Archer Road, Summit-Argo, IL 60501, USA Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 1347 EP - 1352 VL - 63 IS - 10 SN - 0362-028X, 0362-028X KW - ribotyping KW - Microbiology Abstracts B: Bacteriology KW - J 02846:Gastrointestinal tract UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18387355?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Food+Protection&rft.atitle=Differentiation+between+Types+and+Strains+of+Clostridium+botulinum+by+Riboprinting&rft.au=Skinner%2C+GE%3BGendel%2C+S+M%3BFingerhut%2C+G+A%3BUlaszek%2C+J%3BSolomon%2C+HA&rft.aulast=Skinner&rft.aufirst=GE&rft.date=2000-10-01&rft.volume=63&rft.issue=10&rft.spage=1347&rft.isbn=&rft.btitle=&rft.title=Journal+of+Food+Protection&rft.issn=0362028X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 ER - TY - JOUR T1 - Tuberculosis (TB) and HIV infection are independently associated with elevated serum concentrations of tumour necrosis factor receptor type 1 and beta sub(2)-microglobulin, respectively AN - 18247393; 5306893 AB - The aim of this study was to identify immune markers that are independently associated with HIV infection or TB in vivo. Using commercially available assays, we measured concentrations of five immune markers in sera from 175 out-patients attending medical clinics in Cote D'Ivoire and Ghana, West Africa. Patients were categorized into groups with TB only (TB super(+)HIV super(-), n = 55), TB and HIV co-infection (TB super(+)HIV super(+), n = 50), HIV infection only (TB super(-)HIV super(+), n = 35), or neither infection (TB super(-)HIV super(-), n = 35). TB super(+)HIV super(+) and TB super(-)HIV super(+) groups were matched for blood CD4 super(+) lymphocyte count. Mean plus or minus s.d. concentrations of beta sub(2)-microglobulin were similarly increased in both the TB super(-)HIV super(+) (5.3 plus or minus 2.1 mu g/ml, P < 0.0001) and the TB super(+)HIV super(+) (5.0 plus or minus 1.5 mu g/ml, P < 0.0001) groups compared with the TB super(-)HIV super(-) group (2.2 plus or minus 1.8 mu g/ml), but were only slightly increased in the TB super(+)HIV super(-) group (3.2 plus or minus 1.8 mu g/ml, P = 0.01). In contrast, mean serum concentrations of soluble tumour necrosis factor receptor type I (sTNF-RI) were similarly elevated in the TB super(+)HIV super(-) (1873 plus or minus 799 pg/ml, P < 0.0001) and TB super(+)HIV super(+) (1797 plus or minus 571 pg/ml, P < 0.0001) groups compared with uninfected subjects (906 plus or minus 613 pg/ml), but there was only a small increase in sTNF-RI in the TB super(-)HIV super(+) group (1231 plus or minus 165 pg/ml, P = 0.03). Both TB and HIV infection were associated with substantial elevation of serum concentrations of soluble CD8, soluble CD54, and sTNF-R type II. Analysis of additional samples from groups of TB super(+)HIV super(-) and TB super(+)HIV super(+) patients receiving anti-TB treatment showed significant and equal reductions in mean serum sTNF-RI concentrations, but no significant change in mean beta sub(2)-microglobulin. Thus, serum beta sub(2)-microglobulin and sTNF-RI serve as relatively independent markers of HIV infection and TB, respectively, in studies of co-infected persons. JF - Clinical and Experimental Immunology AU - Lawn, S D AU - Rudolph, D AU - Wiktor, S AU - Coulibaly, D AU - Ackah, A AU - Lal, R B AD - HIV and Retrovirology Branch, Division of AIDS, STD, and TB Laboratory Research, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA, USA, and Projet Retro-CI and Centres Antituberculeux, Abidjan, Cote D'Ivoire, West Africa, sil3@cdc.gov Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 79 EP - 84 PB - Blackwell Science Ltd VL - 122 IS - 1 SN - 0009-9104, 0009-9104 KW - infection KW - man KW - HIV KW - beta -Microglobulin KW - beta 2-microglobulin KW - tumor necrosis factor receptors KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Immunology Abstracts KW - b2-microglobulin KW - ^b-Microglobulin KW - Ghana KW - Acquired immune deficiency syndrome KW - Tumor necrosis factor KW - Human immunodeficiency virus KW - Africa, West KW - Tuberculosis KW - Cote d'Ivoire KW - Markers KW - Mycobacterium tuberculosis KW - F 06801:Bacteria KW - J 02833:Immune response and immune mechanisms KW - V 22003:AIDS: Immunological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18247393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Experimental+Immunology&rft.atitle=Tuberculosis+%28TB%29+and+HIV+infection+are+independently+associated+with+elevated+serum+concentrations+of+tumour+necrosis+factor+receptor+type+1+and+beta+sub%282%29-microglobulin%2C+respectively&rft.au=Lawn%2C+S+D%3BRudolph%2C+D%3BWiktor%2C+S%3BCoulibaly%2C+D%3BAckah%2C+A%3BLal%2C+R+B&rft.aulast=Lawn&rft.aufirst=S&rft.date=2000-10-01&rft.volume=122&rft.issue=1&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Experimental+Immunology&rft.issn=00099104&rft_id=info:doi/10.1046%2Fj.1365-2249.2000.01341.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Mycobacterium tuberculosis; Human immunodeficiency virus; Cote d'Ivoire; Ghana; Africa, West; Tuberculosis; Acquired immune deficiency syndrome; Markers; Tumor necrosis factor DO - http://dx.doi.org/10.1046/j.1365-2249.2000.01341.x ER - TY - JOUR T1 - Semen Quality and Hormone Levels Among Radiofrequency Heater Operators AN - 18163031; 4791982 AB - Approximately 9,000,000 US workers are occupationally exposed to radiofrequency (RF) radiation; over 250,000 operate RF dielectric heaters. Our purpose was to determine whether male RF heater operators experience increased adverse reproductive effects reflected in reduced semen quality or altered hormone levels. We measured incident RF heater radiation exposures and RF-induced foot currents at four companies. For 12 male heater operators and a comparison group of 34 RF-unexposed men, we measured 33 parameters of semen quality and four serum hormones. Despite wide variation in individual exposure levels, near field strengths and induced foot currents did not exceed current standard levels and guidelines. We observed minor semen quality and hormonal differences between the groups, including a slightly higher mean follicle-stimulating hormone level for exposed operators (7.6 vs 5.8 mIU/mL). Further occupational studies of RF-exposed men may be warranted. JF - Journal of Occupational and Environmental Medicine AU - Grajewski, B AU - Cox, C AU - Schrader, S M AU - Murray, W E AU - Edwards, R M AU - Turner, T W AU - Smith, J M AU - Shekar, S S AU - Evenson, D P AU - Simon, S D AU - Conover, D L AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mail Stop R-44, 4676 Columbia Parkway, Cincinnati, OH 45226, USA Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 993 EP - 1005 VL - 42 IS - 10 SN - 1076-2752, 1076-2752 KW - radiofrequency KW - man KW - hormones KW - semen KW - Toxicology Abstracts; Health & Safety Science Abstracts; Pollution Abstracts KW - Hormones KW - Radiation KW - Semen KW - Reproduction KW - Occupational exposure KW - H 8000:Radiation Safety/Electrical Safety KW - X 24210:Radiation & radioactive materials KW - P 8000:RADIATION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18163031?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Semen+Quality+and+Hormone+Levels+Among+Radiofrequency+Heater+Operators&rft.au=Grajewski%2C+B%3BCox%2C+C%3BSchrader%2C+S+M%3BMurray%2C+W+E%3BEdwards%2C+R+M%3BTurner%2C+T+W%3BSmith%2C+J+M%3BShekar%2C+S+S%3BEvenson%2C+D+P%3BSimon%2C+S+D%3BConover%2C+D+L&rft.aulast=Grajewski&rft.aufirst=B&rft.date=2000-10-01&rft.volume=42&rft.issue=10&rft.spage=993&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Reproduction; Radiation; Occupational exposure; Semen; Hormones ER - TY - JOUR T1 - Staphylococcal enterotoxins AN - 17726383; 4786819 AB - Staphylococcus aureus is a major human pathogen that produces a wide array of toxins, thus causing various types of disease symptoms. Staphylococcal enterotoxins (SEs), a family of nine major serological types of heat stable enterotoxins, are a leading cause of gastroenteritis resulting from consumption of contaminated food. In addition, SEs are powerful superantigens that stimulate non-specific T-cell proliferation. SEs share close phylogenetic relationships, with similar structures and activities. Here we review the structure and function of each known enterotoxin. JF - International Journal of Food Microbiology AU - Balaban, N AU - Rasooly, A AD - Center of Veterinary Medicine, US Food and Drug Administration, Washington DC, USA, axr@vm.cfsan.fda.gov Y1 - 2000/10/01/ PY - 2000 DA - 2000 Oct 01 SP - 1 EP - 10 VL - 61 IS - 1 SN - 0168-1605, 0168-1605 KW - Staphylococcus aureus KW - enterotoxins KW - food poisoning KW - gastroenteritis KW - Health & Safety Science Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Superantigens KW - Reviews KW - Food poisoning KW - Enterotoxins KW - Gastroenteritis KW - Food contamination KW - A 01017:Human foods KW - H 4000:Food and Drugs KW - A 01023:Others UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17726383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Food+Microbiology&rft.atitle=Staphylococcal+enterotoxins&rft.au=Balaban%2C+N%3BRasooly%2C+A&rft.aulast=Balaban&rft.aufirst=N&rft.date=2000-10-01&rft.volume=61&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Food+Microbiology&rft.issn=01681605&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Staphylococcus aureus; Reviews; Food contamination; Enterotoxins; Gastroenteritis; Food poisoning; Superantigens ER - TY - JOUR T1 - Testing the potential of flaxseed to affect spermatogenesis: morphometry AN - 17726312; 4789713 AB - Quantitative information was collected on male reproductive effects of maternal and postnatal dietary exposure to flaxseed (20 or 40%), flaxmeal (13 or 26%) or standard NIH AIN-93 feed (0% flaxseed control). Measurements were made on the testes of F1 generation males rats (1) whose mothers were exposed to the diets designated above, and (2) who, after weaning, were placed on the same diet as their mothers for an additional 70 days. The seminiferous tubules comprised 86%, 84%, 84%, 84% and 85% of the total testis volume while the interstitial space comprised 12%, 14%, 14%, 14%, 13% of the total testis volume for the 0% flaxseed/flaxmeal, 20% flaxseed, 13% flaxmeal, 40% flaxseed and 26% flaxmeal groups, respectively. Statistically significant decreases in the absolute volume of the seminiferous tubules were observed in the 20% and 40% flaxseed-treated groups when these groups were compared to controls. Borderline statistically significant differences were also observed when Sertoli cell nucleolar number per tubular cross-section were compared in the 13% flaxmeal and 20% flaxseed treatment groups. These effects were not considered biologically significant because other parameters of male reproductive function appeared normal. Overall, the quantitative information obtained suggests that exposure to flaxseed/flaxmeal at the doses used in the present study does not adversely affect testis structure or spermatogenesis in the rat. JF - Food and Chemical Toxicology AU - Sprando, R L AU - Collins, TFX AU - Wiesenfeld, P AU - Babu, U S AU - Rees, C AU - Black, T AU - Olejnik, N AU - Rorie, J AD - Division of Toxicological Research, Center for Food Safety Applied Nutrition, Food and Drug Administration, 8301 Muirkirk Road, Beltsville, MD 20708, USA, RLS@vm.cfsan.fda.gov Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 887 EP - 892 VL - 38 IS - 10 SN - 0278-6915, 0278-6915 KW - rats KW - linseed KW - Toxicology Abstracts KW - Seminiferous tubule KW - Testes KW - Sexual reproduction KW - Spermatogenesis KW - Linum usitatissimum KW - X 24120:Food, additives & contaminants KW - X 24172:Plants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17726312?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+and+Chemical+Toxicology&rft.atitle=Testing+the+potential+of+flaxseed+to+affect+spermatogenesis%3A+morphometry&rft.au=Sprando%2C+R+L%3BCollins%2C+TFX%3BWiesenfeld%2C+P%3BBabu%2C+U+S%3BRees%2C+C%3BBlack%2C+T%3BOlejnik%2C+N%3BRorie%2C+J&rft.aulast=Sprando&rft.aufirst=R&rft.date=2000-10-01&rft.volume=38&rft.issue=10&rft.spage=887&rft.isbn=&rft.btitle=&rft.title=Food+and+Chemical+Toxicology&rft.issn=02786915&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Linum usitatissimum; Testes; Sexual reproduction; Seminiferous tubule; Spermatogenesis ER - TY - JOUR T1 - Influence of melatonin on immunotoxicity of lead AN - 17707236; 4776315 AB - The results suggested that immunotoxicity induced by lead [Pb, as Pb(NO sub(3)) sub(2)] was significantly restored or prevented by melatonin (MLT). MLT (10 or 50 mg/kg) was orally administered to ICR mice daily for 28 days, and Pb was also administered at 35 mg/kg in the same way 2 h after the administration of MLT, and the normal mice were given vehicle. Within the Pb plus MLT-treated group, the body weight gains and the relative thymus weights were significantly increased when compared with the treatment of Pb alone. The relative spleen and liver weights were increased by the treatment of Pb alone, and then restored to normal value by MLT treatment. Hemagglutination (HA) titer, plaque-forming cell response to sheep red blood cell (SRBC), and secondary IgG antibody response to BSA were significantly enhanced in the Pb plus MLT-treated mice, as opposed to when compared with the treatment of Pb alone. The mitogenic response of splenic T cell to concanavalin A and that of B cells to lipopolysaccharide was remarkably increased by MLT treatment when compared with treatment of Pb alone. Splenic CD4 super(+) cells were significantly increased by MLT treatment when compared with treatment of Pb alone. In case of CD8 super(+) cells, the slight enhancement was observed in MLT treatment. Splenic T and B cells were significantly increased by MLT treatment when compared with the treatment of Pb alone. The natural killer cell, phagocytic activity and the number of peripheral leukocytes were significantly enhanced in Pb plus MLT-treated mice when compared with the treatment of Pb alone. JF - International Journal of Immunopharmacology AU - Kim, Young-Ok AU - Pyo, Myoung-Yun AU - Kim, Joung-Hoon AD - Immunotoxicology Division, Toxicology Department, National Institute of Toxicological Research, Korea FDA, Eunpyung-Ku, Seoul 122-704, South Korea, okjutwo@yahoo.com Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 821 EP - 832 VL - 22 IS - 10 SN - 0192-0561, 0192-0561 KW - toxicity KW - mice KW - immunology KW - lead KW - melatonin KW - Toxicology Abstracts; Immunology Abstracts KW - Sheep red blood cells KW - Heavy metals KW - Lymphocytes B KW - Natural killer cells KW - Spleen KW - Antibody response KW - Hemagglutination KW - Lead KW - Immunotoxicity KW - Immune response (cell-mediated) KW - Liver KW - Immunoglobulin G KW - Lymphocytes T KW - Melatonin KW - Phagocytosis KW - X 24164:Pathology KW - F 06793:Immunopharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17707236?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Immunopharmacology&rft.atitle=Influence+of+melatonin+on+immunotoxicity+of+lead&rft.au=Kim%2C+Young-Ok%3BPyo%2C+Myoung-Yun%3BKim%2C+Joung-Hoon&rft.aulast=Kim&rft.aufirst=Young-Ok&rft.date=2000-10-01&rft.volume=22&rft.issue=10&rft.spage=821&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Immunopharmacology&rft.issn=01920561&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Lymphocytes T; Lymphocytes B; Sheep red blood cells; Immunoglobulin G; Antibody response; Spleen; Liver; Hemagglutination; Heavy metals; Melatonin; Lead; Immunotoxicity; Natural killer cells; Phagocytosis; Immune response (cell-mediated) ER - TY - JOUR T1 - Purification and characterization of a cytotonic protein expressed in vitro by the live cholera vaccine candidate CVD 103-HgR AN - 17696462; 4783904 AB - Cholera vaccines developed by the deletion of CTX genes from Vibrio cholerae induce a residual reactogenicity in up to 10% of vaccinees. A novel cytotonic agent named secreted CHO cell elongating protein (S-CEP) was purified from culture supernatants of CVD 103-HgR (Levine et al., Lancet ii:467-470, 1988). Five fractionation steps yielded electrophoretically pure S-CEP with an M sub(r) of 79,000. A partially purified preparation caused fluid accumulation in the sealed infant mouse model. The amino terminus bore a unique sequence with strong homology to a cytotonic toxin of El Tor V. cholerae. JF - Infection and Immunity AU - Sathyamoorthy, V AU - Hall, R H AU - McCardell, BA AU - Kothary, M H AU - Ahn, S J AU - Ratnayake, Sh AD - Food and Drug Administration, CFSAN/DVA/HFS 327, Washington, DC 20204, USA, rhh@cfsan.fda.gov Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 6062 EP - 6065 VL - 68 IS - 10 SN - 0019-9567, 0019-9567 KW - S-CEP protein KW - ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts B: Bacteriology KW - Molecular structure KW - Human diseases KW - Deletion mutant KW - Electrophoresis KW - Amino acids KW - Pathogenic bacteria KW - Chromatography KW - Animal models KW - Freshwater KW - Toxins KW - Vibrio cholerae KW - Genes KW - Live KW - Vaccines KW - Q1 08206:Physiology, biochemistry, biophysics KW - J 02834:Vaccination and immunization UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17696462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+and+Immunity&rft.atitle=Purification+and+characterization+of+a+cytotonic+protein+expressed+in+vitro+by+the+live+cholera+vaccine+candidate+CVD+103-HgR&rft.au=Sathyamoorthy%2C+V%3BHall%2C+R+H%3BMcCardell%2C+BA%3BKothary%2C+M+H%3BAhn%2C+S+J%3BRatnayake%2C+Sh&rft.aulast=Sathyamoorthy&rft.aufirst=V&rft.date=2000-10-01&rft.volume=68&rft.issue=10&rft.spage=6062&rft.isbn=&rft.btitle=&rft.title=Infection+and+Immunity&rft.issn=00199567&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Last updated - 2014-05-06 N1 - SubjectsTermNotLitGenreText - Molecular structure; Human diseases; Amino acids; Genes; Pathogenic bacteria; Vaccines; Electrophoresis; Deletion mutant; Chromatography; Live; Animal models; Toxins; Vibrio cholerae; Freshwater ER - TY - JOUR T1 - Cloning, expression, and characterization of the katG gene, encoding catalase-peroxidase, from the polycyclic aromatic hydrocarbon-degrading bacterium Mycobacterium sp. strain PYR-1 AN - 17647232; 4795319 AB - A 81-kDa protein from Mycobacterium sp. strain PYR-1 was expressed in response to exposure of the strain to the polycyclic aromatic hydrocarbon pyrene and recovered by two-dimensional gel electrophoresis. The N-terminal sequence of the protein indicated that it was similar to catalase-peroxidase. An oligonucleotide probe designed from this sequence was used to screen a genomic library of Mycobacterium sp. strain PYR-1, and a positive clone, containing a part of the gene encoding the 81-kDa protein, was isolated. A gene-walking technique was used to sequence the entire gene, which was identified as katG for catalase-peroxidase. The deduced KatG protein sequence showed significant homology to KatGII of Mycobacterium fortuitum and clustered with catalase-peroxidase proteins from other Mycobacterium species in a phylogenetic tree. The katG gene was expressed in Escherichia coli to produce a protein with catalase-peroxidase activity. Since the induction of this catalase-peroxidase occurred in pyrene-induced cultures and the exposure of these cultures to hydrogen peroxide reduced pyrene metabolism, our data suggest that this enzyme plays a role in polycyclic aromatic hydrocarbon metabolism by strain PYR-1. JF - Applied and Environmental Microbiology AU - Wang, R-F AU - Wennerstrom, D AU - Gao, W-W AU - Khan, A A AU - Cerniglia, CE AD - Microbiology Division, National Center for Toxicological Research, FDA, Jefferson, AR 72079, USA, CCerniglia@nctr.fda.gov Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 4300 EP - 4304 VL - 66 IS - 10 SN - 0099-2240, 0099-2240 KW - cDNA KW - amino acid sequence prediction KW - KatG protein KW - katG gene KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology KW - Polycyclic aromatic hydrocarbons KW - Hydrocarbons KW - Mycobacterium KW - Genotyping KW - Peroxidase KW - Nucleotide sequence KW - Mycobacterium fortuitum KW - Pyrene KW - Catalase KW - Gene expression KW - Hydrogen peroxide KW - Escherichia coli KW - Proteins KW - G 07320:Bacterial genetics KW - J 02740:Genetics and evolution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17647232?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Cloning%2C+expression%2C+and+characterization+of+the+katG+gene%2C+encoding+catalase-peroxidase%2C+from+the+polycyclic+aromatic+hydrocarbon-degrading+bacterium+Mycobacterium+sp.+strain+PYR-1&rft.au=Wang%2C+R-F%3BWennerstrom%2C+D%3BGao%2C+W-W%3BKhan%2C+A+A%3BCerniglia%2C+CE&rft.aulast=Wang&rft.aufirst=R-F&rft.date=2000-10-01&rft.volume=66&rft.issue=10&rft.spage=4300&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.66.10.4300-4304.2000 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Mycobacterium; Mycobacterium fortuitum; Escherichia coli; Polycyclic aromatic hydrocarbons; Nucleotide sequence; Catalase; Peroxidase; Pyrene; Hydrogen peroxide; Gene expression; Hydrocarbons; Proteins; Genotyping DO - http://dx.doi.org/10.1128/AEM.66.10.4300-4304.2000 ER - TY - JOUR T1 - Cold shock induction of thermal sensitivity in Listeria monocytogenes AN - 17641165; 4795326 AB - Cold shock at 0 to 15 degree C for 1 to 3 h increased the thermal sensitivity of Listeria monocytogenes. In a model broth system, thermal death time at 60 degree C was reduced by up to 45% after L. monocytogenes Scott A was cold shocked for 3 h. The duration of the cold shock affected thermal tolerance more than did the magnitude of the temperature downshift. The Z values were 8.8 degree C for controls and 7.7 degree C for cold-shocked cells. The D values of cold-shocked cells did not return to control levels after incubation for 3 h at 28 degree C followed by heating at 60 degree C. Nine L. monocytogenes strains that were cold shocked for 3 h exhibited D sub(60) values that were reduced by 13 to 37%. The D-value reduction was greatest in cold-shocked stationary-phase cells compared to cells from cultures in either the lag or exponential phases of growth. In addition, cold-shocked cells were more likely to be inactivated by a given heat treatment than nonshocked cells, which were more likely to experience sublethal injury. The D values of chloramphenicol-treated control cells and chloramphenicol-treated cold-shocked cells were no different from those of untreated cold-shocked cells, suggesting that cold shock suppresses synthesis of proteins responsible for heat protection. In related experiments, the D values of L. monocytogenes Scott A were decreased 25% on frankfurter skins and 15% in ultra-high temperature milk if the inoculated products were first cold shocked. Induction of increased thermal sensitivity in L. monocytogenes by thermal flux shows potential to become a practical and efficacious preventative control method. JF - Applied and Environmental Microbiology AU - Miller, A J AU - Bayles, DO AU - Eblen, BSh AD - U.S. Food & Drug Administration, Center for Food Safety and Applied Nutrition, Mail Stop HFS-32, 200 C Street S.W., Washington, DC 20204, USA, amiller@cfsan.fda.gov Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 4345 EP - 4350 VL - 66 IS - 10 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts B: Bacteriology KW - Listeria monocytogenes KW - Chloramphenicol KW - Heat tolerance KW - Cold shock KW - J 02722:Biodegradation, growth, nutrition and leaching UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17641165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Cold+shock+induction+of+thermal+sensitivity+in+Listeria+monocytogenes&rft.au=Miller%2C+A+J%3BBayles%2C+DO%3BEblen%2C+BSh&rft.aulast=Miller&rft.aufirst=A&rft.date=2000-10-01&rft.volume=66&rft.issue=10&rft.spage=4345&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.66.10.4345-4350.2000 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Listeria monocytogenes; Cold shock; Heat tolerance; Chloramphenicol DO - http://dx.doi.org/10.1128/AEM.66.10.4345-4350.2000 ER - TY - JOUR T1 - Characterization of fluoroquinolone resistance among veterinary isolates of avian Escherichia coli AN - 17636384; 4784083 AB - Fluoroquinolone-resistant avian Escherichia coli isolates from northern Georgia were investigated for gyrA and parC mutations. All isolates contained a mutation in GyrA replacing Ser83 with Leu; seven isolates also contained mutations replacing Asp87 with either Gly or Tyr. Random amplified polymorphic DNA analysis revealed that quinolone-resistant E. coli isolates were genetically diverse. JF - Antimicrobial Agents & Chemotherapy AU - White, D G AU - Piddock, LJV AU - Maurer, J J AU - Zhao, Sh AU - Ricci, V AU - Thayer, S G AD - Office of Research, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD 20708, USA, dwhite@cvm.fda.gov Y1 - 2000/10// PY - 2000 DA - Oct 2000 SP - 2897 EP - 2899 VL - 44 IS - 10 SN - 0066-4804, 0066-4804 KW - GyrA protein KW - gyrA gene KW - parC gene KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Genetic variance KW - Fluoroquinolones KW - Drug resistance KW - USA, Georgia KW - Escherichia coli KW - Antibacterial agents KW - Mutation KW - A 01064:Microbial resistance KW - J 02814:Drug resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17636384?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Characterization+of+fluoroquinolone+resistance+among+veterinary+isolates+of+avian+Escherichia+coli&rft.au=White%2C+D+G%3BPiddock%2C+LJV%3BMaurer%2C+J+J%3BZhao%2C+Sh%3BRicci%2C+V%3BThayer%2C+S+G&rft.aulast=White&rft.aufirst=D&rft.date=2000-10-01&rft.volume=44&rft.issue=10&rft.spage=2897&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.44.10.2897-2899.2000 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Escherichia coli; USA, Georgia; Antibacterial agents; Fluoroquinolones; Drug resistance; Mutation; Genetic variance DO - http://dx.doi.org/10.1128/AAC.44.10.2897-2899.2000 ER - TY - JOUR T1 - Mutations selected in rotavirus enterotoxin NSP4 depend on the context of its expression. AN - 72308083; 11017794 AB - The rotavirus NSP4 protein is cytotoxic when transiently expressed in cells and is capable of inducing secretory diarrhea in neonatal mice. NSP4 consists of 175 amino acids, and sequences important for its toxic effects have been mapped to the carboxy-terminal half of the protein. In this report, we compared NSP4-encoding nucleotide sequences recovered from cell lines engineered to express NSP4 from human rotavirus strain Wa with NSP4 sequences recovered from cells persistently infected with either Wa or simian rotavirus strain SA11. In cells stably transfected with Wa NSP4, we found that proline(138) was changed to either serine or threonine. However, in cells persistently infected with SA11, we found that phenylalanine(33) was changed to leucine, and in cells persistently infected with Wa, no changes were observed in NSP4. Expression of Wa NSP4 in Caco-2 cells resulted in increased cell-doubling times and decreased cell viability in comparison to cells expressing NSP4-serine(138) or NSP4-threonine(138). This result suggests that sequence polymorphism at residue 138 in Wa NSP4 influences the cytotoxicity of the protein. Therefore, mutations in the carboxy-terminal half of NSP4 are selected when NSP4 is expressed in cells in the absence of other viral proteins, but not in the context of viral replication. These findings suggest that cytotoxic functions of NSP4 are not operant during natural rotavirus infection. Copyright 2000 Academic Press. JF - Virology AU - Mohan, K V AU - Dermody, T S AU - Atreya, C D AD - Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA. Y1 - 2000/09/15/ PY - 2000 DA - 2000 Sep 15 SP - 125 EP - 132 VL - 275 IS - 1 SN - 0042-6822, 0042-6822 KW - Glycoproteins KW - 0 KW - NS28 protein, rotavirus KW - RNA, Messenger KW - Toxins, Biological KW - Viral Nonstructural Proteins KW - Index Medicus KW - Animals KW - DNA Mutational Analysis KW - Humans KW - Polymorphism, Genetic -- genetics KW - Gene Expression KW - RNA, Messenger -- analysis KW - Caco-2 Cells KW - RNA, Messenger -- genetics KW - Cell Survival KW - Virulence KW - Phenotype KW - Transfection KW - Amino Acid Substitution -- genetics KW - Cell Line KW - Cell Division KW - Viral Nonstructural Proteins -- biosynthesis KW - Viral Nonstructural Proteins -- genetics KW - Glycoproteins -- biosynthesis KW - Glycoproteins -- metabolism KW - Glycoproteins -- chemistry KW - Viral Nonstructural Proteins -- chemistry KW - Rotavirus -- pathogenicity KW - Mutation -- genetics KW - Rotavirus -- genetics KW - Glycoproteins -- genetics KW - Viral Nonstructural Proteins -- metabolism KW - Rotavirus -- physiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72308083?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Virology&rft.atitle=Mutations+selected+in+rotavirus+enterotoxin+NSP4+depend+on+the+context+of+its+expression.&rft.au=Mohan%2C+K+V%3BDermody%2C+T+S%3BAtreya%2C+C+D&rft.aulast=Mohan&rft.aufirst=K&rft.date=2000-09-15&rft.volume=275&rft.issue=1&rft.spage=125&rft.isbn=&rft.btitle=&rft.title=Virology&rft.issn=00426822&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-31 N1 - Date created - 2000-10-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Breeds of dogs involved in fatal human attacks in the United States between 1979 and 1998. AN - 72272628; 10997153 AB - To summarize breeds of dogs involved in fatal human attacks during a 20-year period and to assess policy implications. Dogs for which breed was reported involved in attacks on humans between 1979 and 1998 that resulted in human dog bite-related fatalities (DBRF). Data for human DBRF identified previously for the period of 1979 through 1996 were combined with human DBRF newly identified for 1997 and 1998. Human DBRF were identified by searching news accounts and by use of The Humane Society of the United States' registry databank. During 1997 and 1998, at least 27 people died of dog bite attacks (18 in 1997 and 9 in 1998). At least 25 breeds of dogs have been involved in 238 human DBRF during the past 20 years. Pit bull-type dogs and Rottweilers were involved in more than half of these deaths. Of 227 reports with relevant data, 55 (24%) human deaths involved unrestrained dogs off their owners' property, 133 (58%) involved unrestrained dogs on their owners' property, 38 (17%) involved restrained dogs on their owners' property, and 1 (< 1%) involved a restrained dog off its owner's property. Although fatal attacks on humans appear to be a breed-specific problem (pit bull-type dogs and Rottweilers), other breeds may bite and cause fatalities at higher rates. Because of difficulties inherent in determining a dog's breed with certainty, enforcement of breed-specific ordinances raises constitutional and practical issues. Fatal attacks represent a small proportion of dog bite injuries to humans and, therefore, should not be the primary factor driving public policy concerning dangerous dogs. Many practical alternatives to breed-specific ordinances exist and hold promise for prevention of dog bites. JF - Journal of the American Veterinary Medical Association AU - Sacks, J J AU - Sinclair, L AU - Gilchrist, J AU - Golab, G C AU - Lockwood, R AD - US Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA. Y1 - 2000/09/15/ PY - 2000 DA - 2000 Sep 15 SP - 836 EP - 840 VL - 217 IS - 6 SN - 0003-1488, 0003-1488 KW - Index Medicus KW - Animals KW - Restraint, Physical -- veterinary KW - Animals, Domestic -- physiology KW - Animals, Domestic -- classification KW - Humans KW - Retrospective Studies KW - Animals, Domestic -- psychology KW - Child KW - United States -- epidemiology KW - Male KW - Female KW - Child, Preschool KW - Dogs -- classification KW - Dogs -- psychology KW - Dogs -- physiology KW - Bites and Stings -- mortality KW - Public Policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72272628?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Veterinary+Medical+Association&rft.atitle=Breeds+of+dogs+involved+in+fatal+human+attacks+in+the+United+States+between+1979+and+1998.&rft.au=Sacks%2C+J+J%3BSinclair%2C+L%3BGilchrist%2C+J%3BGolab%2C+G+C%3BLockwood%2C+R&rft.aulast=Sacks&rft.aufirst=J&rft.date=2000-09-15&rft.volume=217&rft.issue=6&rft.spage=836&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Veterinary+Medical+Association&rft.issn=00031488&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-20 N1 - Date created - 2000-11-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Development of a transgenic mouse neurovirulence test for oral poliovirus vaccine: international collaborative study 1993-1999 AN - 17656030; 4767789 AB - The neurovirulence safety of oral live poliovirus vaccine (OPV) has been tested in monkeys, because only primates are sensitive to all three types of poliovirus. The genetic engineering of transgenic mice susceptible to poliovirus led to studies on the suitability of these mice for a neurovirulence test of OPV. A WHO international collaborative study started with type-3 OPV in 1993 and was completed in 1999. The study produced a voluminous set of data proving that the TgPVR21 mice, inoculated with OPV samples into the lumbar cord, provided a test for neurovirulence of OPV as sensitive and reproducible as the monkey test. A statistical decision model for acceptance/rejection of type-3 vaccines using the transgenic mouse test has been developed. The mouse neurovirulence test showed a number of essential advantages over the monkey test. This is the first example of a successful introduction of transgenic animals into control of biologicals. In October 1999, the WHO Expert Committee on Biological Standardization approved TgPVR21 mice as alternative to the monkey model for neurovirulence testing of OPV type 3. A final step of the collaborative study with OPV types 1 and 2 is in progress, and data obtained so far are promising. Two breeding stations for production of TgPVR21 mice are being established in Asia and Europe. JF - Vaccine AU - Levenbook, I AU - Dragunsky, E AU - Pervikov, Y AD - Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA Y1 - 2000/09/15/ PY - 2000 DA - 2000 Sep 15 SP - 163 EP - 166 VL - 19 IS - 2-3 SN - 0264-410X, 0264-410X KW - transgenic mice KW - immunology KW - poliovirus KW - Biotechnology and Bioengineering Abstracts; Virology & AIDS Abstracts; Medical and Pharmaceutical Biotechnology Abstracts; Immunology Abstracts KW - Poliovirus KW - International cooperation KW - Safety KW - Neurovirulence KW - Attenuation KW - Nervous system diseases KW - Vaccines KW - W3 33365:Vaccines (other) KW - F 06807:Active immunization KW - V 22150:Animal models & experimentally-induced viral infections KW - V 22097:Immunization: Vaccines & vaccination: Human KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17656030?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Development+of+a+transgenic+mouse+neurovirulence+test+for+oral+poliovirus+vaccine%3A+international+collaborative+study+1993-1999&rft.au=Levenbook%2C+I%3BDragunsky%2C+E%3BPervikov%2C+Y&rft.aulast=Levenbook&rft.aufirst=I&rft.date=2000-09-15&rft.volume=19&rft.issue=2-3&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Poliovirus; Neurovirulence; Vaccines; International cooperation; Nervous system diseases; Safety; Attenuation ER - TY - JOUR T1 - Postlicensure Safety Surveillance for Varicella Vaccine AN - 17817687; 4858384 AB - Since its licensure in 1995, the extensive use of varicella vaccine and close surveillance of the associated anecdotal reports of suspected adverse effects provide the opportunity to detect potential risks not observed before licensure because of the relatively small sample size and other limitations of clinical trials. To detect potential hazards, including rare events, associated with varicella vaccine, and to assess case reports for clinical and epidemiological implications. Postlicensure case-series study of suspected vaccine adverse events reported to the US Vaccine Adverse Event Reporting System (VAERS) from March 17, 1995, through July 25, 1998. Numbers of reported adverse events, proportions, and reporting rates (reports per 100,000 doses distributed). VAERS received 6574 case reports of adverse events in recipients of varicella vaccine, a rate of 67.5 reports per 100,000 doses sold. Approximately 4% of reports described serious adverse events, including 14 deaths. The most frequently reported adverse events were rashes, possible vaccine failures, and injection site reactions. Misinterpretation of varicella serology after vaccination appeared to account for 17% of reports of possible vaccine failures. Among 251 patients with herpes zoster, 14 had the vaccine strain of varicella zoster virus (VZV), while 12 had the wild-type virus. None of 30 anaphylaxis cases was fatal. An immunodeficient patient with pneumonia had the vaccine strain of VZV in a lung biopsy. Pregnant women occasionally received varicella vaccine through confusion with varicella zoster immunoglobulin. Although the role of varicella vaccine remained unproven in most serious adverse event reports, there were a few positive rechallenge reports and consistency of many cases with syndromes recognized as complications of natural varicella. Most of the reported adverse events associated with varicella vaccine are minor, and serious risks appear to be rare. We could not confirm a vaccine etiology for most of the reported serious events; several will require further study to clarify whether varicella vaccine plays a role. Education is needed to ensure appropriate use of varicella serologic assays and to eliminate confusion between varicella vaccine and varicella zoster immunoglobulin. JF - Journal of the American Medical Association AU - Wise, R P AU - Salive, ME AU - Braun, M M AU - Mootrey, G T AU - Seward, J F AU - Rider, L G AU - Krause, PR AD - 1401 Rockville Pike, FDA CBER HFM-225, Rockville, MD 20852-1448, USA, rpwise@cber.fda.gov Y1 - 2000/09/13/ PY - 2000 DA - 2000 Sep 13 SP - 1271 EP - 1279 VL - 284 IS - 10 SN - 0098-7484, 0098-7484 KW - Varicella-zoster virus KW - vaccines KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Safety KW - Vaccines KW - Side effects KW - Immunoglobulins KW - V 22097:Immunization: Vaccines & vaccination: Human KW - A 01097:Viruses KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17817687?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Medical+Association&rft.atitle=Postlicensure+Safety+Surveillance+for+Varicella+Vaccine&rft.au=Wise%2C+R+P%3BSalive%2C+ME%3BBraun%2C+M+M%3BMootrey%2C+G+T%3BSeward%2C+J+F%3BRider%2C+L+G%3BKrause%2C+PR&rft.aulast=Wise&rft.aufirst=R&rft.date=2000-09-13&rft.volume=284&rft.issue=10&rft.spage=1271&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Medical+Association&rft.issn=00987484&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Varicella-zoster virus; Side effects; Vaccines; Safety; Immunoglobulins ER - TY - JOUR T1 - Determination of chlorophacinone and diphacinone in commercial rodenticides by liquid chromatography-UV detection and liquid chromatography-electrospray ionization mass spectrometry. AN - 72352446; 11043785 AB - This work describes a simple method for the determination and mass-spectrometric confirmation of the indanediones in commercial rodenticides. The sample is sonicated in methanol containing 2% formic acid and analyzed by liquid chromatography-UV detection. Once retention time and UV-Vis spectrum provide tentative identification, mass-spectrometric confirmation is obtained by analyzing a second aliquot by LC and electrospray ionization mass spectrometry (LC-ESI-MS). The extensive fragmentation of the indanedione molecule under MS/MS conditions provides sufficient structural information for positive identification on analyte levels as low as 20 ng on column. JF - Journal of chromatography. A AU - Mesmer, M Z AU - Flurer, R A AD - United States Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH 45237-3097, USA. Y1 - 2000/09/08/ PY - 2000 DA - 2000 Sep 08 SP - 249 EP - 255 VL - 891 IS - 2 SN - 0021-9673, 0021-9673 KW - Indans KW - 0 KW - Rodenticides KW - chlorophacinone KW - 34Y6E0063Y KW - diphenadione KW - 54CA01C6JX KW - Phenindione KW - 5M7Y6274ZE KW - Index Medicus KW - Sensitivity and Specificity KW - Spectrometry, Mass, Electrospray Ionization KW - Spectrophotometry, Ultraviolet KW - Indans -- analysis KW - Chromatography, Liquid -- methods KW - Phenindione -- analysis KW - Rodenticides -- chemistry KW - Phenindione -- analogs & derivatives UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72352446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chromatography.+A&rft.atitle=Determination+of+chlorophacinone+and+diphacinone+in+commercial+rodenticides+by+liquid+chromatography-UV+detection+and+liquid+chromatography-electrospray+ionization+mass+spectrometry.&rft.au=Mesmer%2C+M+Z%3BFlurer%2C+R+A&rft.aulast=Mesmer&rft.aufirst=M&rft.date=2000-09-08&rft.volume=891&rft.issue=2&rft.spage=249&rft.isbn=&rft.btitle=&rft.title=Journal+of+chromatography.+A&rft.issn=00219673&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-08 N1 - Date created - 2001-02-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Changes in bronchoalveolar lavage indices associated with radiographic classification in coal miners. AN - 85272673; pmid-10988113 AB - Previous studies on symptomatic coal miners have shown that alveolar macrophages, recovered by bronchoalveolar lavage (BAL), release excessive amounts of reactive oxygen species (ROS) and inflammatory cytokines. It has been proposed that these secretions may mediate cell injury and initiate the disease process. We hypothesized that acellular bronchoalveolar lavage fluid (BALF) indices in coal miners chronically exposed to coal dust may reflect the status of important homeostatic modulations in the lung that lead to the development of coal workers' pneumoconiosis (CWP). To test this hypothesis, we measured inflammatory status, oxidant burden, antioxidant defenses, cytokines, growth factors, fibronectin, and alpha(1)-antitrypsin (alpha(1)-AT) in the BALF of healthy never-smoker control subjects, never-smoker underground coal miners with negative radiographs (ILO 0/0-1/0), and two miners with moderate changes in the chest radiographs (ILO 2/2). Interestingly, indices of injury and inflammation increased with the progression of disease in coal miners. Antioxidant enzymes, such as catalase, glutathione peroxidase, and superoxide dismutase, showed a 19-fold, 22-fold, and 6-fold increase above control, respectively, in coal miners with category 2/2 CWP. Significant increases in the secretion of IL-1, IL-6, TNF-alpha, TGF-beta, fibronectin, and alpha(1)-AT also were evident in coal miners with disease. This up-regulation of antioxidant defenses and cytokines was not evident in coal miners in the absence of clinically evident radiographic disease. In addition, the concentration of lipid peroxidation by products in the BALF of coal miners without evidence of radiographic disease showed a moderate 3-fold increase, whereas, in coal miners with category 2/2 CWP it showed a 59-fold increase compared to control subjects. These results are in good agreement with our hypothesis that development of CWP and its progression may be correlated with an oxidative stress and up-regulation of cytokines and mediators of growth. JF - American Journal of Respiratory and Critical Care Medicine AU - Vallyathan, V AU - Goins, M AU - Lapp, L N AU - Pack, D AU - Leonard, S AU - Shi, X AU - Castranova, V AD - Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, and Section of Pulmonary and Critical Care Medicine, West Virginia University, Morgantown, West Virginia, USA. PY - 2000 SP - 958 EP - 965 VL - 162 IS - 3 Pt 1 SN - 1073-449X, 1073-449X KW - Lung KW - Human KW - Oxidative Stress KW - Bronchoalveolar Lavage Fluid KW - Adult KW - Pneumoconiosis KW - Middle Age KW - Inflammation Mediators KW - Cytokines KW - Predictive Value of Tests KW - Reactive Oxygen Species KW - Lipid Peroxidation KW - Male UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/85272673?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Respiratory+and+Critical+Care+Medicine&rft.atitle=Changes+in+bronchoalveolar+lavage+indices+associated+with+radiographic+classification+in+coal+miners.&rft.au=Vallyathan%2C+V%3BGoins%2C+M%3BLapp%2C+L+N%3BPack%2C+D%3BLeonard%2C+S%3BShi%2C+X%3BCastranova%2C+V&rft.aulast=Vallyathan&rft.aufirst=V&rft.date=2000-09-01&rft.volume=162&rft.issue=3+Pt+1&rft.spage=958&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Respiratory+and+Critical+Care+Medicine&rft.issn=1073449X&rft_id=info:doi/ LA - eng DB - ComDisDome N1 - Last updated - 2010-05-07 ER - TY - JOUR T1 - Attention deficit/hyperactivity disorder: characteristics, interventions and models. AN - 72467595; 11106857 AB - An epidemiological study of Attention Deficit/Hyperactivity Disorder (ADHD) suggests that the prevalence may be two to three times higher than the figure of 3-5% often cited. In addition, the data suggest that both underdiagnosis and overdiagnosis occur frequently. Rodent animal models of ADHD, like the Spontaneously Hypertensive Rat (SHR) and other rat models such as those with chemical and radiation-induced brain lesions and cerebellar stunting, and the Coloboma mouse model exhibit clear similarities with several aspects of the human disorder and should prove useful in studying specific traits. Operant behavioral tasks that model learning, short-term memory and simple discriminations are sensitive to ADHD and methylphenidate has been shown to normalize ADHD performance in a short-term memory task. Recent findings challenge not only the current postulate that response inhibition is a unique deficit in ADHD, but also the concepts of ADHD and its treatment, which presume intact perceptual abilities. Time perception deficits may account, in part, for the excessive variability in motor response times on speeded reaction time tasks, motor control problems and motor clumsiness associated with ADHD. The Multimodality Treatment Study of ADHD (MTA) provided data suggesting that pharmacological interventions that included systematic and frequent follow-up with parents and teachers, with or without psychosocial interventions, are superior to psychosocial interventions or standard community care alone. Additionally, the MTA was one of the first studies to demonstrate benefits of multimodal and pharmacological interventions lasting longer than 1 year. Imaging studies have demonstrated differences in brain areas in children with ADHD: anterior corpus callosum, right anterior white matter, and cerebellar volumes are all decreased in children with ADHD and there is less brain asymmetry in ADHD subjects. Additionally, functional imaging studies, coupled with pharmacological manipulations, suggest decreased blood flow and energy utilization in prefrontal cortex and striatum and the dysregulation of catecholamine systems in persons with ADHD. JF - Neurotoxicology and teratology AU - Paule, M G AU - Rowland, A S AU - Ferguson, S A AU - Chelonis, J J AU - Tannock, R AU - Swanson, J M AU - Castellanos, F X AD - Behavioral Toxicology Laboratory, Division of Neurotoxicology, HFT-132, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079-9502, USA. mpaule@nctr.fda.gov PY - 2000 SP - 631 EP - 651 VL - 22 IS - 5 SN - 0892-0362, 0892-0362 KW - Index Medicus KW - Animals KW - Humans KW - Disease Models, Animal KW - Attention Deficit Disorder with Hyperactivity -- therapy KW - Attention Deficit Disorder with Hyperactivity -- physiopathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72467595?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+teratology&rft.atitle=Attention+deficit%2Fhyperactivity+disorder%3A+characteristics%2C+interventions+and+models.&rft.au=Paule%2C+M+G%3BRowland%2C+A+S%3BFerguson%2C+S+A%3BChelonis%2C+J+J%3BTannock%2C+R%3BSwanson%2C+J+M%3BCastellanos%2C+F+X&rft.aulast=Paule&rft.aufirst=M&rft.date=2000-09-01&rft.volume=22&rft.issue=5&rft.spage=631&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+teratology&rft.issn=08920362&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-11 N1 - Date created - 2000-12-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Characterization of galactomannans by capillary electrophoresis. AN - 72430713; 11091784 AB - Capillary electrophoresis (CE) was utilized in the characterization of various galactomannans. Standards of gums were extracted with 50% CH3CN to remove the residual proteins from the gum matrix. Separation buffers were optimized with respect to pH, buffer concentration and presence of sodium dodecyl sulphate, yielding protein profiles from which the desired information could be obtained. Examples are given of the profiles generated by various gums and gum blends to aid in the verification of component presence, and to demonstrate levels of adulteration detectable under the buffer conditions used. JF - Food additives and contaminants AU - Flurer, C L AD - Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio 45237, USA. cflurer@ora.fda.gov Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 721 EP - 731 VL - 17 IS - 9 SN - 0265-203X, 0265-203X KW - Galactans KW - 0 KW - Mannans KW - Plant Extracts KW - Plant Gums KW - Plant Proteins KW - Polysaccharides KW - galactomannan KW - 11078-30-1 KW - guar gum KW - E89I1637KE KW - locust bean gum KW - V4716MY704 KW - Index Medicus KW - Plant Proteins -- analysis KW - Electrophoresis, Capillary -- standards KW - Electrophoresis, Capillary -- methods KW - Galactans -- chemistry KW - Polysaccharides -- chemistry KW - Mannans -- analysis KW - Mannans -- chemistry KW - Plants, Medicinal KW - Food Contamination -- analysis KW - Cassia -- chemistry KW - Plant Extracts -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72430713?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+additives+and+contaminants&rft.atitle=Characterization+of+galactomannans+by+capillary+electrophoresis.&rft.au=Flurer%2C+C+L&rft.aulast=Flurer&rft.aufirst=C&rft.date=2000-09-01&rft.volume=17&rft.issue=9&rft.spage=721&rft.isbn=&rft.btitle=&rft.title=Food+additives+and+contaminants&rft.issn=0265203X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-12-13 N1 - Date created - 2000-12-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A long-term study of the development of N2O controls at a pediatric dental facility. AN - 72400176; 11071429 AB - A review is given of National Institute for Occupational Safety and Health (NIOSH) efforts to control N2O at a pediatric dental operatory from 1978 to the present. Measurements of N2O concentrations were made on four occasions before and after installation of different controls, using an infrared analyzer. Air velocity and volumetric flow measurements also were taken, Video imaging was done in some cases simultaneously with real-time N2O measurements to correlate work practices with exposure data. An infrared imaging system was used to identify sources of N2O. Critical components of resulting recommendations for control include monitoring of N2O concentrations; use of engineering controls, such as a scavenging mask, an effective dilution ventilation system, and auxiliary exhaust; good work practices; maintenance of the equipment; and worker education. Data presented strongly supports the hypothesis that better implementation of controls leads to reduction of N2O exposures. N2O concentrations were reduced by a factor of 61 from their initial levels. The current NIOSH recommended exposure limit of 25 ppm TWA during the time of N2O administration appears to be achievable. JF - AIHAJ : a journal for the science of occupational and environmental health and safety AU - Crouch, K G AU - McGlothlin, J D AU - Johnston, O E AD - U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. PY - 2000 SP - 753 EP - 756 VL - 61 IS - 5 SN - 1529-8663, 1529-8663 KW - Nitrous Oxide KW - K50XQU1029 KW - Index Medicus KW - United States KW - Pediatrics KW - Humans KW - National Institute for Occupational Safety and Health (U.S.) KW - Gas Scavengers -- standards KW - Occupational Exposure -- prevention & control KW - Dental Facilities -- standards KW - Occupational Exposure -- standards KW - Nitrous Oxide -- analysis KW - Ventilation -- standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72400176?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIHAJ+%3A+a+journal+for+the+science+of+occupational+and+environmental+health+and+safety&rft.atitle=A+long-term+study+of+the+development+of+N2O+controls+at+a+pediatric+dental+facility.&rft.au=Crouch%2C+K+G%3BMcGlothlin%2C+J+D%3BJohnston%2C+O+E&rft.aulast=Crouch&rft.aufirst=K&rft.date=2000-09-01&rft.volume=61&rft.issue=5&rft.spage=753&rft.isbn=&rft.btitle=&rft.title=AIHAJ+%3A+a+journal+for+the+science+of+occupational+and+environmental+health+and+safety&rft.issn=15298663&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-03-22 N1 - Date created - 2001-01-31 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Male adolescent exposure to endocrine-disrupting pesticides: vinclozolin exposure in peripubertal rabbits. AN - 72312721; 11021521 AB - Adolescence is a time of dramatic neuroendocrine changes that are required for sexual maturation. Hormonal mimicking or inhibiting chemicals can cause significant impairment during this critical period. Vinclozolin (Vin) has been shown to be an anti-androgen affecting male offspring in rats in utero, and its mechanism of action may be mediated by inhibition of androgenic receptor action. The majority of teenagers working on farms are male, and therefore a systemic fungicide, vinclozolin, was selected for study. The rabbit has proved to be an excellent species for modelling reproductive toxicant effects in the male and was selected as the test species. The peripubertal phase for the rabbit was determined to be between the 3rd and 4th months. A 2-month dosing period was therefore initiated at 3 months of age and carried through to the 4th month. Vin was administered by dermal application (100 mg kg(-1) in 100 microl of dimethylsulphoxide) daily. Body weights were determined weekly. The rabbits were then held until fully mature (6 months of age). Semen was collected and evaluated from sexually mature males on a weekly schedule for 5 weeks to maximize sperm output. An automated solid phase extraction procedure for monitoring exposures through isolation and quantification of Vin and its metabolic products was developed. Increased plasma levels of Vin and M2 were found throughout the experimental period. The exposed rabbits had a smaller weight gain during pubertal growth (approaching significance; P=0.059). At maturity, the accessory sex glands of the exposed animals weighed less than those of the controls (P=0.016). Surprisingly, the pooled sperm count of the exposed animals was significantly higher (P=0.017) than that of the unexposed animals. The anti-androgenic effects of Vin may have blocked the negative feedback mechanism of testosterone on the hypothalamus or pituitary gland, allowing for an increase in gonadotrophin release, and consequently increasing sperm production at puberty. JF - Andrologia AU - Moorman, W J AU - Cheever, K L AU - Skaggs, S R AU - Clark, J C AU - Turner, T W AU - Marlow, K L AU - Schrader, S M AD - Division of Biomedical and Behavioral Sciences, National Institute for Occupational Safety and Health, Cincinnati, OH, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 285 EP - 293 VL - 32 IS - 4-5 SN - 0303-4569, 0303-4569 KW - Androgen Antagonists KW - 0 KW - Fungicides, Industrial KW - Oxazoles KW - vinclozolin KW - JJ258EZN1I KW - Index Medicus KW - Rats KW - Occupational Exposure KW - Models, Animal KW - Animals KW - Sperm Count KW - Humans KW - Rabbits KW - Male KW - Sexual Maturation -- drug effects KW - Oxazoles -- metabolism KW - Androgen Antagonists -- toxicity KW - Androgen Antagonists -- metabolism KW - Endocrine Glands -- drug effects KW - Fungicides, Industrial -- metabolism KW - Fungicides, Industrial -- toxicity KW - Oxazoles -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72312721?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Andrologia&rft.atitle=Male+adolescent+exposure+to+endocrine-disrupting+pesticides%3A+vinclozolin+exposure+in+peripubertal+rabbits.&rft.au=Moorman%2C+W+J%3BCheever%2C+K+L%3BSkaggs%2C+S+R%3BClark%2C+J+C%3BTurner%2C+T+W%3BMarlow%2C+K+L%3BSchrader%2C+S+M&rft.aulast=Moorman&rft.aufirst=W&rft.date=2000-09-01&rft.volume=32&rft.issue=4-5&rft.spage=285&rft.isbn=&rft.btitle=&rft.title=Andrologia&rft.issn=03034569&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-02-08 N1 - Date created - 2001-02-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - In vivo drug-drug interaction studies--a survey of all new molecular entities approved from 1987 to 1997. AN - 72302975; 11014409 AB - Ninety-eight new molecular entities applications approved between 1987 to 1991 (period I) and 193 applications for new molecular entities between 1992 to 1997 (period II) were surveyed for drug-drug interaction studies. In period I (used as a comparator), 32 applications contained drug-drug interaction studies for a total of 117 studies. In period II, 106 applications reported drug-drug interaction studies, and the number of studies per new molecular entity ranged from 0 to 15. Most studies (77%) were performed in healthy subjects, with 44% using crossover designs, 7% using parallel designs, and the remaining using fixed sequence designs. The most common dosing scheme for new molecular entities/interacting drug was multiple dose (47%), whereas single dose/multiple dose was used in 31% of studies, and single dose/single dose was used in 18% of studies. Of the 540 drug-drug interaction studies submitted in period II, 80 (15%) resulted in clinically significant labeling statements. Submissions for new molecular entities to the Center for Drug Evaluation and Research divisions most likely to include drug-drug interaction studies were neuropharmacology, cardiorenal, antiviral, and antiinfective drugs. Some drug classes such as oncology drug products and radioimaging products were least likely to include drug-drug interaction studies in their submissions. We conclude that the use of drug-drug interaction studies in the drug development process has increased between the two periods. JF - Clinical pharmacology and therapeutics AU - Marroum, P J AU - Uppoor, R S AU - Parmelee, T AU - Ajayi, F AU - Burnett, A AU - Yuan, R AU - Svadjian, R AU - Lesko, L J AU - Balian, J D AD - Office of Clinical Pharmacology and Biopharmaceutics, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD 20857, USA. marroump@cder.fda.gov Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 280 EP - 285 VL - 68 IS - 3 SN - 0009-9236, 0009-9236 KW - Abridged Index Medicus KW - Index Medicus KW - United States KW - Drug Administration Schedule KW - United States Food and Drug Administration KW - Dose-Response Relationship, Drug KW - Humans KW - Databases, Factual KW - Cross-Over Studies KW - Clinical Trials as Topic KW - Drug Interactions KW - Biopharmaceutics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72302975?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+pharmacology+and+therapeutics&rft.atitle=In+vivo+drug-drug+interaction+studies--a+survey+of+all+new+molecular+entities+approved+from+1987+to+1997.&rft.au=Marroum%2C+P+J%3BUppoor%2C+R+S%3BParmelee%2C+T%3BAjayi%2C+F%3BBurnett%2C+A%3BYuan%2C+R%3BSvadjian%2C+R%3BLesko%2C+L+J%3BBalian%2C+J+D&rft.aulast=Marroum&rft.aufirst=P&rft.date=2000-09-01&rft.volume=68&rft.issue=3&rft.spage=280&rft.isbn=&rft.btitle=&rft.title=Clinical+pharmacology+and+therapeutics&rft.issn=00099236&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-17 N1 - Date created - 2000-10-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Empirical Bayes adjustments for multiple results in hypothesis-generating or surveillance studies. AN - 72297009; 11008906 AB - Traditional methods of adjustment for multiple comparisons (e.g., Bonferroni adjustments) have fallen into disuse in epidemiological studies. However, alternative kinds of adjustment for data with multiple comparisons may sometimes be advisable. When a large number of comparisons are made, and when there is a high cost to investigating false positive leads, empirical or semi-Bayes adjustments may help in the selection of the most promising leads. Here we offer an example of such adjustments in a large surveillance data set of occupation and cancer in Nordic countries, in which we used empirical Bayes (EB) adjustments to evaluate standardized incidence ratios (SIRs) for cancer and occupation among craftsmen and laborers. For men, there were 642 SIRs, of which 138 (21%) had a P 1.0 and 8% negative with SIR < or = 1.0) when testing the null hypothesis of no cancer/occupation association; some of these were probably due to confounding by nonoccupational risk factors (e.g., smoking). After EB adjustments, there were 95 (15%) SIRs with P < 0.05 (10% positive and 5% negative). For women, there were 373 SIRs, of which 37 (10%) had P < 0.05 before adjustment (6% positive and 4% negative) and 13 (3%) had P < 0.05 after adjustment (2% positive and 1% negative). Several known associations were confirmed after EB adjustment (e.g., pleural cancer among plumbers, original SIR 3.2 (95% confidence interval, 2.5-4.1), adjusted SIR 2.0 (95% confidence interval, 1.6-2.4). EB can produce more accurate estimates of relative risk by shrinking imprecise outliers toward the mean, which may reduce the number of false positives otherwise flagged for further investigation. For example, liver cancer among chimney sweepers was reduced from an original SIR of 2.2 (range, 1.1-4.4) to an adjusted SIR of 1.1 (range, 0.9-1.4). A potentially important future application for EB is studies of gene-environment-disease interactions, in which hundreds of polymorphisms may be evaluated with dozens of environmental risk factors in large cohort studies, producing thousands of associations. JF - Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology AU - Steenland, K AU - Bray, I AU - Greenland, S AU - Boffetta, P AD - National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 895 EP - 903 VL - 9 IS - 9 SN - 1055-9965, 1055-9965 KW - Carcinogens KW - 0 KW - Index Medicus KW - Odds Ratio KW - Analysis of Variance KW - Social Class KW - Humans KW - Incidence KW - Scandinavian and Nordic Countries -- epidemiology KW - Male KW - Female KW - Risk Assessment KW - Occupational Exposure -- statistics & numerical data KW - Neoplasms -- epidemiology KW - Bayes Theorem KW - Population Surveillance -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72297009?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.atitle=Empirical+Bayes+adjustments+for+multiple+results+in+hypothesis-generating+or+surveillance+studies.&rft.au=Steenland%2C+K%3BBray%2C+I%3BGreenland%2C+S%3BBoffetta%2C+P&rft.aulast=Steenland&rft.aufirst=K&rft.date=2000-09-01&rft.volume=9&rft.issue=9&rft.spage=895&rft.isbn=&rft.btitle=&rft.title=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.issn=10559965&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2001-01-11 N1 - Date created - 2001-01-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A nationwide outbreak of alopecia associated with the use of a hair-relaxing formulation. AN - 72262451; 10987865 AB - To study the long-term outcome of adverse effects reported by persons who used a commercial hair-straightening product known as the Rio Hair Naturalizer System (World Rio Corporation). Survey of individuals who contacted the Food and Drug Administration in 1994 and 1995 to report adverse effects linked to using the product. Persons residing in the United States. A total of 464 (59% of 790 eligible) patients who returned a completed questionnaire. Adverse effects associated with using the Rio Hair Naturalizer System products (neutral or color enhancer). Ninety percent of respondents were African American women between the ages of 15 and 55 years. The most common complaints associated with the use of the products were hair breakage and/or hair loss, reported by 95% of respondents. Three quarters of those experiencing hair loss reported losing 40% or more of their original hair. The median time between the loss of original hair and the growth of new hair was 8 months; however, 40 (9%) respondents reported having no new growth at the time of completing the survey, some 2 years after using the product. When mixed according to package instructions, the mean pH of a sample of 20 neutral product kits tested was 1.39 (range, 1.1-3.15). For the 21 color-enhancer products tested, the mean pH was 2.82 (range, 2. 29-3.08). A nationwide outbreak of alopecia and scalp injuries involving tens of thousands of women (and some men) occurred following the marketing of a chemical hair-relaxing product. Most of those affected reported substantial hair loss, with a majority indicating growth of new hair that was abnormal in both quantity and quality. JF - Archives of dermatology AU - Swee, W AU - Klontz, K C AU - Lambert, L A AD - Food and Drug Administration, HFS-728, 200 C St SW, Washington, DC 20204, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 1104 EP - 1108 VL - 136 IS - 9 SN - 0003-987X, 0003-987X KW - Hair Preparations KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - United States KW - Humans KW - Adult KW - Product Surveillance, Postmarketing KW - Middle Aged KW - Adolescent KW - African Continental Ancestry Group KW - Male KW - Female KW - Hair Preparations -- adverse effects KW - Disease Outbreaks KW - Alopecia -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72262451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+dermatology&rft.atitle=A+nationwide+outbreak+of+alopecia+associated+with+the+use+of+a+hair-relaxing+formulation.&rft.au=Swee%2C+W%3BKlontz%2C+K+C%3BLambert%2C+L+A&rft.aulast=Swee&rft.aufirst=W&rft.date=2000-09-01&rft.volume=136&rft.issue=9&rft.spage=1104&rft.isbn=&rft.btitle=&rft.title=Archives+of+dermatology&rft.issn=0003987X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-03 N1 - Date created - 2000-10-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Sensitization of cancer cells to interleukin 13-pseudomonas exotoxin-induced cell death by gene transfer of interleukin 13 receptor alpha chain. AN - 72261947; 10986556 AB - We have demonstrated that primary interleukin 13 (IL-13) binding protein IL-13 receptor (IL-13R) alpha chain plays an important role in IL-13 binding and internalization in the IL-13R system. Although IL-13R alpha chain is expressed on many cancer cell lines, some cancer types do not express or express low levels of this receptor chain. Consequently, these cells show no or low sensitivity to the cytotoxic effect of a recombinant chimeric protein composed of IL-13 and a mutated form of a Pseudomonas exotoxin, IL13-PE38QQR. Here we demonstrate that pancreatic cancer, renal cell carcinoma, head and neck cancer, and glioblastoma cell lines that were genetically altered to express high levels of IL-13R alpha chain increase their binding affinity for IL-13, and increase their sensitivity to IL13-PE38QQR by at least 6-fold to 1000-fold compared with mock-transfected control cells. This observation was made by protein synthesis inhibition assay and confirmed by clonogenic assay. Our studies provide a proof of principle for a novel strategy for cancer therapy that combines gene transfer and targeted cytotoxin therapy. JF - Human gene therapy AU - Kawakami, K AU - Joshi, B H AU - Puri, R K AD - Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA. Y1 - 2000/09/01/ PY - 2000 DA - 2000 Sep 01 SP - 1829 EP - 1835 VL - 11 IS - 13 SN - 1043-0342, 1043-0342 KW - Antineoplastic Agents KW - 0 KW - Bacterial Toxins KW - Exotoxins KW - IL13RA1 protein, human KW - Interleukin-13 KW - Interleukin-13 Receptor alpha1 Subunit KW - Iodine Radioisotopes KW - Receptors, Interleukin KW - Receptors, Interleukin-13 KW - Recombinant Proteins KW - Virulence Factors KW - ADP Ribose Transferases KW - EC 2.4.2.- KW - toxA protein, Pseudomonas aeruginosa KW - EC 2.4.2.31 KW - Index Medicus KW - Exotoxins -- genetics KW - Exotoxins -- pharmacology KW - Recombinant Proteins -- pharmacology KW - Tumor Cells, Cultured KW - Transfection KW - Humans KW - Inhibitory Concentration 50 KW - Recombinant Proteins -- genetics KW - Colony-Forming Units Assay KW - Gene Transfer Techniques KW - Interleukin-13 -- metabolism KW - Receptors, Interleukin -- genetics KW - Receptors, Interleukin -- drug effects KW - Cell Death -- genetics KW - Cell Death -- drug effects KW - Antineoplastic Agents -- pharmacology KW - Interleukin-13 -- genetics KW - Interleukin-13 -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72261947?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+gene+therapy&rft.atitle=Sensitization+of+cancer+cells+to+interleukin+13-pseudomonas+exotoxin-induced+cell+death+by+gene+transfer+of+interleukin+13+receptor+alpha+chain.&rft.au=Kawakami%2C+K%3BJoshi%2C+B+H%3BPuri%2C+R+K&rft.aulast=Kawakami&rft.aufirst=K&rft.date=2000-09-01&rft.volume=11&rft.issue=13&rft.spage=1829&rft.isbn=&rft.btitle=&rft.title=Human+gene+therapy&rft.issn=10430342&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-26 N1 - Date created - 2000-10-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Identifying toxic degradation products in cellulose acetate dialyzers. AN - 72257443; 10984691 AB - In September 1996, seven patients at Hospital A suffered conjunctivitis, hearing loss, diminished vision, and headaches 7-24 h after hemodialysis treatment. Eleven-year-old dialysis modules were identified as a common link between these patients. Degradation of the cellulose acetate (CA) material was identified as the cause of this incident. Degradation products were characterized from retrieved CA dialysis membranes. A series of synthesized CA degradation products was tested in vitro to assess toxicity. Based on the toxicity of the material preparations to the cells, animal tests were performed on selected CA degradation extracts and compared to extracts from actual dialysis membranes. Rabbits were IV-injected with extracts from a 13-year-old dialyzer, synthesized model compounds, and compared to controls. Ophthamological evaluation of the rabbits showed eye injury (iritis/ciliary flush) when the animals were treated with the old dialyzer or synthesized model compounds. Isolation and characterization of a toxic fraction from both of these extracts strongly indicated that oxidative stress at some point in the storage or manufacture of CA dialyzers created degradation products that reproduced some of the patient symptoms identified at Hospital A. JF - Journal of biomedical materials research AU - Lucas, A D AU - Kalson, J A AU - Hutter, J C AU - Wallis, R R AD - U.S. Food and Drug Administration, CDRH/OST, Rockville MD 20852, USA. adl@cdrh.fda.gov Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 449 EP - 456 VL - 53 IS - 5 SN - 0021-9304, 0021-9304 KW - Biocompatible Materials KW - 0 KW - Membranes, Artificial KW - acetylcellulose KW - 3J2P07GVB6 KW - Cellulose KW - 9004-34-6 KW - Index Medicus KW - Biocompatible Materials -- chemistry KW - Animals KW - Biocompatible Materials -- toxicity KW - Vision Disorders -- etiology KW - Cell Survival -- drug effects KW - Humans KW - Jurkat Cells KW - Deafness -- etiology KW - Rabbits KW - Conjunctivitis -- etiology KW - Headache -- etiology KW - Female KW - Cellulose -- analogs & derivatives KW - Renal Dialysis -- standards KW - Cellulose -- toxicity KW - Renal Dialysis -- instrumentation KW - Cellulose -- chemistry KW - Equipment Failure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72257443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+biomedical+materials+research&rft.atitle=Identifying+toxic+degradation+products+in+cellulose+acetate+dialyzers.&rft.au=Lucas%2C+A+D%3BKalson%2C+J+A%3BHutter%2C+J+C%3BWallis%2C+R+R&rft.aulast=Lucas&rft.aufirst=A&rft.date=2000-09-01&rft.volume=53&rft.issue=5&rft.spage=449&rft.isbn=&rft.btitle=&rft.title=Journal+of+biomedical+materials+research&rft.issn=00219304&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-11-03 N1 - Date created - 2000-11-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Determination of total sulfur compounds and benzothiazole in asphalt fume samples by gas chromatography with sulfur chemiluminescence detection. AN - 72256148; 10983404 AB - As part of a collaborative project between the National Institute for Occupational Safety and Health and the Federal Highway Administration to evaluate asphalt pavers' exposures to asphalt fume and their potential health effects, a method was developed for the determination of total sulfur compounds and benzothiazole in asphalt fume samples. Asphalt fume samples were collected from asphalt mixtures with and without the addition of ground-up rubber tires. The asphalt fume samples were collected with sampling trains that consisted of a Teflon membrane filter and an XAD-2 adsorbent tube. Filter and sampling tube media were extracted with hexane and subsequently analyzed by gas chromatography with a sulfur chemiluminescence detector. Separation was achieved with a 100 percent dimethyl polysiloxane fused silica column. Typical calibration curves had linear correlation coefficients of 0.99 or better with a relative standard deviation (RSD) of 5 percent. Benzothiazole desorption efficiency (DE) determined using spiked sampling tubes ranged from 96.5 percent at 5.0 micrograms to 89.4 percent at 40 micrograms with RSD values from 0.9 to 4.0 percent. Benzothiazole storage recovery determined using sampling tubes spiked at 20 micrograms and refrigerated for 30 days at 4 degrees C was 89.8 percent when corrected for the DE with an RSD of 1.1 percent. The limit of detection for the method determined using spiked sampling tubes was 0.30 microgram. Quantitation for total sulfur compounds and benzothiazole was against benzothiazole standards in hexane. Because of detector selectivity, sample preparation consisted of a simple hexane extraction even when samples had a high background due to hydrocarbon overload. Detector sensitivity provided quantitation in the sub-microgram region. Because of the sample preparation step and because benzothiazole was determined during the same analysis run, this method is straightforward and analytically efficient. The method has been used to analyze asphalt fume samples collected at several asphalt paving and roof operations. JF - Applied occupational and environmental hygiene AU - Jaycox, L B AU - Olsen, L D AD - Division of Applied Research and Technology, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 695 EP - 704 VL - 15 IS - 9 SN - 1047-322X, 1047-322X KW - Air Pollutants, Occupational KW - 0 KW - Benzothiazoles KW - Hydrocarbons KW - Sulfur Compounds KW - Thiazoles KW - asphalt KW - 8052-42-4 KW - benzothiazole KW - G5BW2593EP KW - Index Medicus KW - Occupational Exposure -- prevention & control KW - Luminescent Measurements KW - Humans KW - Industry KW - Hydrocarbons -- chemistry KW - Sulfur Compounds -- analysis KW - Air Pollutants, Occupational -- adverse effects KW - Sulfur Compounds -- adverse effects KW - Thiazoles -- adverse effects KW - Thiazoles -- analysis KW - Hydrocarbons -- adverse effects KW - Air Pollutants, Occupational -- chemistry KW - Environmental Monitoring -- methods KW - Chromatography, Gas -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72256148?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+occupational+and+environmental+hygiene&rft.atitle=Determination+of+total+sulfur+compounds+and+benzothiazole+in+asphalt+fume+samples+by+gas+chromatography+with+sulfur+chemiluminescence+detection.&rft.au=Jaycox%2C+L+B%3BOlsen%2C+L+D&rft.aulast=Jaycox&rft.aufirst=L&rft.date=2000-09-01&rft.volume=15&rft.issue=9&rft.spage=695&rft.isbn=&rft.btitle=&rft.title=Applied+occupational+and+environmental+hygiene&rft.issn=1047322X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-09-26 N1 - Date created - 2000-09-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Noise exposure to airline ramp employees. AN - 72255227; 10983395 JF - Applied occupational and environmental hygiene AU - Tubbs, R L AD - Hazard Evaluation and Technical Assistance Branch of the National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 657 EP - 663 VL - 15 IS - 9 SN - 1047-322X, 1047-322X KW - Index Medicus KW - United States KW - Ear Protective Devices KW - Noise, Transportation -- prevention & control KW - Humans KW - National Institute for Occupational Safety and Health (U.S.) KW - Noise, Transportation -- adverse effects KW - Aircraft KW - Hearing Loss, Noise-Induced -- etiology KW - Noise, Occupational -- prevention & control KW - Occupational Diseases -- prevention & control KW - Occupational Diseases -- etiology KW - Occupational Exposure -- adverse effects KW - Hearing Loss, Noise-Induced -- prevention & control KW - Noise, Occupational -- adverse effects KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72255227?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+occupational+and+environmental+hygiene&rft.atitle=Noise+exposure+to+airline+ramp+employees.&rft.au=Tubbs%2C+R+L&rft.aulast=Tubbs&rft.aufirst=R&rft.date=2000-09-01&rft.volume=15&rft.issue=9&rft.spage=657&rft.isbn=&rft.btitle=&rft.title=Applied+occupational+and+environmental+hygiene&rft.issn=1047322X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-09-26 N1 - Date created - 2000-09-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of polychlorinated biphenyls on the nervous system. AN - 72247767; 11693948 AB - The neurological effects of polychlorinated biphenyls (PCBs) have been extensively investigated in humans and in animals. The main focus in human studies has been on the effects in neonates and young children, although studies of adults have also been conducted. A great deal of concern exists that even low levels of PCBs transferred to the fetus across the placenta may induce long-lasting neurological damage. Because PCBs are lipophilic substances, there is also concem that significant amounts might be transferred to nursing infants via breast milk. Studies in humans who consumed large amounts of Great Lakes fish contaminated with environmentally persistent chemicals, including PCBs. have provided evidence that PCBs are important contributors to subtle neurobehavioral alterations observed in newborn children and that some of these alterations persist during childhood. Some consistent observations at birth have been motor immaturity and hyporeflexia and lower psychomotor scores between 6 months and 2 years old. There is preliminary evidence that highly chlorinated PCB congeners, which accumulate in certain fish, are associated with neurobehavioral alterations seen in some newbom children. Subtle neurobehavioral alterations have also been observed in children bom to mothers in the general population with the highest PCB body burdens. Because of the limitations of epidemiological studies, these effects cannot be attributed entirely to PCB exposure. In one general population study, there was strong evidence that dioxins, as well as PCBs, were contributors to the neurobehavioral effects seen in exposed children. Children born to women who accidentally consumed rice oil contaminated with relatively high amounts of PCBs and chlorinated dibenzofurans (CDFs) during pregnancy also had neurodevelopmental changes. Studies in animals support the human data. Neurobehavioral alterations have been also observed in rats and monkeys following prenatal and/or postnatal exposure to commercial Aroclor mixtures, defined experimental congener mixtures, single PCB congeners, and Great Lakes contaminated fish. In addition, monkeys exposed postnatally to PCB mixtures of congeneric composition and concentration similar to that found in human breast milk showed learning deficits long after exposure had ceased. A few other generalizations can be made from the data in animals. It appears that ortho-substituted PCB congeners are more active than coplanar PCBs in modifying cognitive processes. In addition, one effect observed in both rats and monkeys--deficits on delayed spatial alternation--has been known to be induced by exposure to ortho-substituted PCBs, defined experimental mixtures, and commercial Aroclors. Both dioxin-like and non-dioxin-like PCB congeners have been shown to induce neurobehavioral alterations in animals. Changes in levels of neurotransmitters in various brain areas have also been observed in monkeys, rats, and mice. Of all the observed changes, the most consistent has been a decrease in dopamine content in basal ganglia and prefrontal cortex, but further research is needed before specific neurobehavioral deficits can be correlated with PCB-induced changes in specific neurotransmitters in specific brain areas. JF - Toxicology and industrial health AU - Faroon, O AU - Jones, D AU - de Rosa, C AD - Agency for Toxic Substances and Disease Registry (ATSDR) US Department of Health and Human Services, Atlanta, Georgia 30333, USA. oxs0@cdc.gov Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 305 EP - 333 VL - 16 IS - 7-8 SN - 0748-2337, 0748-2337 KW - Environmental Pollutants KW - 0 KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - Administration, Oral KW - Animals KW - Humans KW - Infant, Newborn KW - Child Development -- drug effects KW - Disease Models, Animal KW - Child KW - Haplorhini KW - Pregnancy KW - Environmental Monitoring KW - Fishes KW - Adult KW - Food Contamination KW - Male KW - Female KW - Environmental Pollutants -- toxicity KW - Polychlorinated Biphenyls -- toxicity KW - Nervous System -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72247767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+industrial+health&rft.atitle=Effects+of+polychlorinated+biphenyls+on+the+nervous+system.&rft.au=Faroon%2C+O%3BJones%2C+D%3Bde+Rosa%2C+C&rft.aulast=Faroon&rft.aufirst=O&rft.date=2000-09-01&rft.volume=16&rft.issue=7-8&rft.spage=305&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+industrial+health&rft.issn=07482337&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2002-03-08 N1 - Date created - 2001-11-05 N1 - Date revised - 2017-02-15 N1 - SuppNotes - Comment In: Toxicol Ind Health. 2002 Feb;18(1):45-7 [12703682] N1 - Last updated - 2017-02-15 ER - TY - JOUR T1 - Evaluation of in vitro reporter gene induction assays for use in a rapid prescreen for compound selection to test specificity in the Tg.AC mouse short-term carcinogenicity assay. AN - 72221633; 10966510 AB - Under ICH guidelines, short-term carcinogenicity assays such as the Tg.AC assay are allowed alternatives for one species in the 2-year rodent bioassay. The Tg.AC transgenic mouse, which carries the v-Ha-ras oncogene under control of the zeta-globin promoter, develops skin papillomas in response to dermal application of carcinogens and tumor promoters. The appropriate specificity of the Tg.AC model for testing pharmaceuticals has not been systematically evaluated. The selection of candidate test compounds among noncarcinogenic pharmaceuticals would be aided by a high-throughput in vitro prescreen correlative of activity in the in vivo Tg.AC assay. Here we describe the development of a prescreen based on correct response to 24 compounds tested previously in Tg.AC mice. The in vitro prescreens, chosen to reflect molecular pathways possibly involved in Tg.AC papilloma formation, consisted of a zeta-globin promoter-luciferase construct stably expressed in K562 cells (Zeta-Luc) and three of the stress-response element-chloramphenicol acetyltransferase (CAT) fusion constructs stably expressed in HepG2 cells that are part of the CAT-Tox (L)iver assay. The stress response elements chosen were the c-fos promoter, the gadd153 promoter, and p53 response element repeats. Of the four assays, the gadd153-CAT assay showed the strongest concordance with activity in the Tg.AC assay, correctly classifying 78% of Tg.AC positive and 83% of Tg.AC negative compounds. The correlation was further improved by adding the Zeta-Luc assay as a second-stage screen. These cell-based assays will be used in a novel approach to selecting candidate compounds that challenge the specificity of the Tg.AC assay toward pharmaceuticals. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Thompson, K L AU - Rosenzweig, B A AU - Tsong, Y AU - Sistare, F D AD - Division of Applied Pharmacology Research, OTR/OPS, Center for Drug Evaluation and Research, Food & Drug Administration, Laurel, Maryland 20708, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 43 EP - 53 VL - 57 IS - 1 SN - 1096-6080, 1096-6080 KW - CCAAT-Enhancer-Binding Proteins KW - 0 KW - DDIT3 protein, human KW - DNA-Binding Proteins KW - Ddit3 protein, mouse KW - Transcription Factors KW - Transcription Factor CHOP KW - 147336-12-7 KW - Globins KW - 9004-22-2 KW - DNA KW - 9007-49-2 KW - Index Medicus KW - Animals KW - Plasmids -- genetics KW - Humans KW - Globins -- genetics KW - DNA-Binding Proteins -- genetics KW - Genes, fos -- genetics KW - Mice KW - Mice, Transgenic KW - Transcription Factors -- genetics KW - Mutagenicity Tests KW - Transfection KW - DNA -- genetics KW - Genes, p53 -- genetics KW - Cell Line KW - Genes, Reporter -- genetics KW - Carcinogenicity Tests UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/72221633?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Evaluation+of+in+vitro+reporter+gene+induction+assays+for+use+in+a+rapid+prescreen+for+compound+selection+to+test+specificity+in+the+Tg.AC+mouse+short-term+carcinogenicity+assay.&rft.au=Thompson%2C+K+L%3BRosenzweig%2C+B+A%3BTsong%2C+Y%3BSistare%2C+F+D&rft.aulast=Thompson&rft.aufirst=K&rft.date=2000-09-01&rft.volume=57&rft.issue=1&rft.spage=43&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=10966080&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-10-13 N1 - Date created - 2000-10-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation. AN - 71749611; 10942736 AB - The present study investigates whether reactive oxygen species (ROS) are involved in p53 activation, and if they are, which species is responsible for the activation. Our hypothesis is that hydroxyl radical (.OH) functions as a messenger for the activation of this tumor suppressor protein. Human lung epithelial cells (A549) were used to test this hypothesis. Cr(VI) was employed as the source of ROS due to its ability to generate a whole spectrum of ROS inside the cell. Cr(VI) is able to activate p53 by increasing the protein levels and enhancing both the DNA binding activity and transactivation ability of the protein. Increased cellular levels of superoxide radicals (O(2)(-).), hydrogen peroxide (H(2)O(2)), and.OH radicals were detected on the addition of Cr(VI) to the cells. Superoxide dismutase, by enhancing the production of H(2)O(2) from O(2)(-). radicals, increased p53 activity. Catalase, an H(2)O(2) scavenger, eliminated.OH radical generation and inhibited p53 activation. Sodium formate and aspirin,.OH radical scavengers, also suppressed p53 activation. Deferoxamine, a metal chelator, inhibited p53 activation by chelating Cr(V) to make it incapable of generating radicals from H(2)O(2). NADPH, which accelerated the one-electron reduction of Cr(VI) to Cr(V) and increased.OH radical generation, dramatically enhanced p53 activation. Thus.OH radical generated from Cr(VI) reduction in A549 cells is responsible for Cr(VI)-induced p53 activation. JF - American journal of physiology. Cell physiology AU - Wang, S AU - Leonard, S S AU - Ye, J AU - Ding, M AU - Shi, X AD - Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown 26505, West Virginia, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - C868 EP - C875 VL - 279 IS - 3 SN - 0363-6143, 0363-6143 KW - Carcinogens, Environmental KW - 0 KW - Free Radicals KW - Tumor Suppressor Protein p53 KW - Chromium KW - 0R0008Q3JB KW - chromium hexavalent ion KW - 18540-29-9 KW - Hydroxyl Radical KW - 3352-57-6 KW - Index Medicus KW - Oxygen Consumption KW - Dose-Response Relationship, Drug KW - Humans KW - Time Factors KW - Free Radicals -- metabolism KW - Cell Line KW - Tumor Suppressor Protein p53 -- physiology KW - Second Messenger Systems -- physiology KW - Hydroxyl Radical -- metabolism KW - Chromium -- pharmacology KW - Carcinogens, Environmental -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/71749611?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+physiology.+Cell+physiology&rft.atitle=The+role+of+hydroxyl+radical+as+a+messenger+in+Cr%28VI%29-induced+p53+activation.&rft.au=Wang%2C+S%3BLeonard%2C+S+S%3BYe%2C+J%3BDing%2C+M%3BShi%2C+X&rft.aulast=Wang&rft.aufirst=S&rft.date=2000-09-01&rft.volume=279&rft.issue=3&rft.spage=C868&rft.isbn=&rft.btitle=&rft.title=American+journal+of+physiology.+Cell+physiology&rft.issn=03636143&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2000-09-14 N1 - Date created - 2000-09-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Prevention of dopaminergic neurotoxicity by targeting nitric oxide and peroxynitrite: implications for the prevention of methamphetamine-induced neurotoxic damage. AN - 70602169; 11085318 AB - Methamphetamine (METH) is a neurotoxic psychostimulant that produces catecholaminergic brain damage by producing oxidative stress and free radical generation. The role of oxygen and nitrogen radicals is well documented as a cause of METH-induced neurotoxic damage. In this study, we have obtained evidence that METH-induced neurotoxicity is the resultant of interaction between oxygen and nitrogen radicals, and it is mediated by the production of peroxynitrite. We have also assessed the effects of inhibitors of neuronal nitric oxide synthase (nNOS) as well as scavenger of nitric oxide and a peroxynitrite decomposition catalyst. Significant protective effects were observed with the inhibitor of nNOS, 7-nitroindazole (7-NI), as well as by the selective peroxynitrite scavenger or decomposition catalyst, 5,10,15,20-tetrakis(2,4,6-trimethyl-3,5-sulfonatophenyl)porphyrinato iron III (FeTPPS). However, the use of a nitric oxide scavenger, 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (c-PTIO), did not provide any significant protection against METH-induced hyperthermia or peroxynitrite generation and the resulting dopaminergic neurotoxicity. In particular, treatment with FeTPPS completely prevented METH-induced hyperthermia, peroxynitrite production, and METH-induced dopaminergic depletion. Together, these data demonstrate that METH-induced dopaminergic neurotoxicity is mediated by the generation of peroxynitrite, which can be selectively protected by nNOS inhibitors or peroxynitrite scavenger or decomposition catalysts. JF - Annals of the New York Academy of Sciences AU - Imam, S Z AU - Islam, F AU - Itzhak, Y AU - Slikker, W AU - Ali, S F AD - Neurochemistry Laboratory, Division of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 157 EP - 171 VL - 914 SN - 0077-8923, 0077-8923 KW - Cyclic N-Oxides KW - 0 KW - Dopamine Uptake Inhibitors KW - Free Radical Scavengers KW - Imidazoles KW - Indazoles KW - Neuroprotective Agents KW - 3,4-Dihydroxyphenylacetic Acid KW - 102-32-9 KW - Peroxynitrous Acid KW - 14691-52-2 KW - 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide KW - 18390-00-6 KW - Nitric Oxide KW - 31C4KY9ESH KW - Tyrosine KW - 42HK56048U KW - Methamphetamine KW - 44RAL3456C KW - 7-nitroindazole KW - UX0N37CMVH KW - Dopamine KW - VTD58H1Z2X KW - Homovanillic Acid KW - X77S6GMS36 KW - Index Medicus KW - Animals KW - Analysis of Variance KW - Drug Administration Schedule KW - Drug Interactions KW - Imidazoles -- pharmacology KW - Corpus Striatum -- metabolism KW - Disease Models, Animal KW - Mice KW - Indazoles -- therapeutic use KW - Homovanillic Acid -- metabolism KW - Models, Biological KW - Electrochemistry -- methods KW - 3,4-Dihydroxyphenylacetic Acid -- metabolism KW - Mice, Inbred C57BL KW - Chromatography, High Pressure Liquid -- methods KW - Cyclic N-Oxides -- pharmacology KW - Corpus Striatum -- drug effects KW - Tyrosine -- metabolism KW - Neuroprotective Agents -- therapeutic use KW - Male KW - Free Radical Scavengers -- pharmacology KW - Peroxynitrous Acid -- metabolism KW - Dopamine Uptake Inhibitors -- toxicity KW - Methamphetamine -- administration & dosage KW - Dopamine Uptake Inhibitors -- administration & dosage KW - Neurotoxicity Syndromes -- prevention & control KW - Neurotoxicity Syndromes -- etiology KW - Nitric Oxide -- metabolism KW - Dopamine -- metabolism KW - Methamphetamine -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70602169?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=Prevention+of+dopaminergic+neurotoxicity+by+targeting+nitric+oxide+and+peroxynitrite%3A+implications+for+the+prevention+of+methamphetamine-induced+neurotoxic+damage.&rft.au=Imam%2C+S+Z%3BIslam%2C+F%3BItzhak%2C+Y%3BSlikker%2C+W%3BAli%2C+S+F&rft.aulast=Imam&rft.aufirst=S&rft.date=2000-09-01&rft.volume=914&rft.issue=&rft.spage=157&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-01-04 N1 - Date created - 2005-11-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure. AN - 70602165; 11085321 AB - A number of substituted amphetamines, including methamphetamine (METH) are considered dopaminergic neurotoxicants. METH causes long-term depletions of striatal dopamine (DA) and its metabolites (DOPAC and HVA) that are accompanied by other changes indicative of nerve terminal degeneration. These include argyrophilia as detected by silver degeneration stains and an elevation in glial fibrillary acidic protein (GFAP), a marker of reactive gliosis in response to injury, as well as a long-term decrease in tyrosine hydroxylase (TH) protein levels. The susceptibility to the dopaminergic neurotoxicity of METH and the other amphetamines can be affected by a number of factors including age, gender, stress, and environment. Many of these susceptibility factors have been extensively investigated in the rat but less so in the mouse. As the availability of genetically altered mice continues to expand, this species is increasingly selected for study. Thus, in previous work we determined that stress, gender, and the environment can significantly impact the neurotoxicity of the amphetamines. Here we determined how age affects the striatal DA depletion and GFAP elevation induced by d-METH in C57BL/6 mice. Age was a significant determinant of the ability of a known neurotoxic regimen of d-METH (10 mg/kg x 4) to produce striatal DA depletion with one-month-old C57BL16 mice displaying minimal and nonpersistent depletion of DA or its metabolites while mice 12 months of age displayed large and persistent depletions of DA (87%), DOPAC (71%), and HVA (94%). Large elevations in striatal GFAP were induced in mice 2-23 months of age by d-METH, with lower dosages of d-METH being effective in the older mice. In contrast, the usual neurotoxic regimen of d-METH was minimally effective in inducing GFAP elevations (49% over control) in one-month-old mice, despite elevations in body temperature equivalent to those observed in older mice. Although increasing the dosage of d-METH (20 to 80 mg/kg) did increase the GFAP response (100% over control), it was still well below that usually exhibited at the usual neurotoxic dosage (300-400% over control) in fully mature mice. These data suggest maturity of striatal dopamine systems may be an essential element in the striatal damage induced by the neurotoxic amphetamines. JF - Annals of the New York Academy of Sciences AU - Miller, D B AU - O'Callaghan, J P AU - Ali, S F AD - Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, NIOSH/CDC, Morgantown, West Virginia 26505, USA. dum6@cdc.gov Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 194 EP - 207 VL - 914 SN - 0077-8923, 0077-8923 KW - Central Nervous System Stimulants KW - 0 KW - 3,4-Dihydroxyphenylacetic Acid KW - 102-32-9 KW - Methamphetamine KW - 44RAL3456C KW - Dopamine KW - VTD58H1Z2X KW - Homovanillic Acid KW - X77S6GMS36 KW - Index Medicus KW - Animals KW - Sex Factors KW - Area Under Curve KW - Body Temperature -- drug effects KW - Dose-Response Relationship, Drug KW - Disease Models, Animal KW - Mice KW - Homovanillic Acid -- metabolism KW - Models, Biological KW - 3,4-Dihydroxyphenylacetic Acid -- metabolism KW - Mice, Inbred C57BL KW - Time Factors KW - Female KW - Male KW - Aging -- physiology KW - Methamphetamine -- administration & dosage KW - Neurotoxicity Syndromes -- etiology KW - Dopamine -- metabolism KW - Corpus Striatum -- drug effects KW - Central Nervous System Stimulants -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70602165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=Age+as+a+susceptibility+factor+in+the+striatal+dopaminergic+neurotoxicity+observed+in+the+mouse+following+substituted+amphetamine+exposure.&rft.au=Miller%2C+D+B%3BO%27Callaghan%2C+J+P%3BAli%2C+S+F&rft.aulast=Miller&rft.aufirst=D&rft.date=2000-09-01&rft.volume=914&rft.issue=&rft.spage=194&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-01-04 N1 - Date created - 2005-11-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Application of electrophysiological method to study interactions between ibogaine and cocaine. AN - 70600721; 11085337 AB - The psychoactive indole alkaloid, ibogaine (IBO), has been investigated for over a decade concerning its reported anti-addictive properties for opioids as well as psychomotor stimulants. The mechanism for the anti-addictive action of IBO is still unclear. IBO interactions with opioid, NMDA, nicotinic, adrenergic, and serotonergic receptor sites have been suggested. The involvement of the dopaminergic system in IBO action is well documented. Increased or decreased levels of dopamine (DA) in specific brain regions following IBO pretreatment have been seen concomitantly with increased or decreased motor activity after subsequent amphetamine or cocaine administration. In this report, in vivo electrophysiological measures were monitored in awake adult male rats in order to investigate alterations of the electrocorticogram (ECoG) resulting from interactions between IBO and cocaine (COC). Rats were implanted bilaterally with bipolar ECoG electrodes. They were either injected with saline, COC alone (20 mg/kg, i.p.) or IBO (50 mg/kg, i.p.) and COC 1 hr later. The concentrations of DA, 5-HT, and their metabolites DOPAC, HVA, and 5-HIAA were assessed in the caudate nucleus in separate groups of saline-, COC-, and IBO/COC-treated rats. An alpha1 power increase was observed within 10 min after COC injection, which lasted for less than 20 min. A desynchronization over alpha2 and both beta power bands was observed throughout the recording. In IBO/COC-treated rats, a significant increase in delta, theta, and alpha1 power occurred within 20 min after COC injection (p <0.05). This effect lasted for up to an hour. DA levels significantly increased after COC only and decreased after IBO administration. A further decrease in levels of DA was observed in IBO/COC-treated rats. DA turnover increased significantly after IBO alone but was not observed after IBO/COC treatment. The alterations in ECoG and neurotransmitter levels suggest a decreased response to COC following IBO pretreatment. JF - Annals of the New York Academy of Sciences AU - Binienda, Z AU - Beaudoin, M A AU - Thorn, B T AU - Sadovova, N AU - Skinner, R D AU - Slikker, W AU - Ali, S F AD - Division of Neurotoxicology, National Center for Toxicological Research/FDA, Jefferson, Arkansas 72079, USA. zbinienda@nctr.fda.gov Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 387 EP - 393 VL - 914 SN - 0077-8923, 0077-8923 KW - Dopamine Uptake Inhibitors KW - 0 KW - Excitatory Amino Acid Antagonists KW - 3,4-Dihydroxyphenylacetic Acid KW - 102-32-9 KW - Serotonin KW - 333DO1RDJY KW - Ibogaine KW - 3S814I130U KW - Hydroxyindoleacetic Acid KW - 54-16-0 KW - Cocaine KW - I5Y540LHVR KW - Dopamine KW - VTD58H1Z2X KW - Homovanillic Acid KW - X77S6GMS36 KW - Index Medicus KW - Animals KW - Analysis of Variance KW - Drug Interactions KW - Brain Chemistry -- drug effects KW - Hydroxyindoleacetic Acid -- metabolism KW - Dopamine -- metabolism KW - Homovanillic Acid -- metabolism KW - Rats KW - Rats, Sprague-Dawley KW - 3,4-Dihydroxyphenylacetic Acid -- metabolism KW - Serotonin -- metabolism KW - Time Factors KW - Wakefulness KW - Male KW - Cerebral Cortex -- drug effects KW - Electroencephalography -- methods KW - Cocaine -- pharmacology KW - Ibogaine -- pharmacology KW - Excitatory Amino Acid Antagonists -- pharmacology KW - Dopamine Uptake Inhibitors -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70600721?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=Application+of+electrophysiological+method+to+study+interactions+between+ibogaine+and+cocaine.&rft.au=Binienda%2C+Z%3BBeaudoin%2C+M+A%3BThorn%2C+B+T%3BSadovova%2C+N%3BSkinner%2C+R+D%3BSlikker%2C+W%3BAli%2C+S+F&rft.aulast=Binienda&rft.aufirst=Z&rft.date=2000-09-01&rft.volume=914&rft.issue=&rft.spage=387&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-01-04 N1 - Date created - 2005-11-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of chronic in utero exposure to cocaine on behavioral adaptability in rhesus monkey offspring when examined in adulthood. AN - 70599173; 11085340 JF - Annals of the New York Academy of Sciences AU - Paule, M G AU - Gillam, M P AU - Allen, R R AU - Chelonis, J J AD - Behavioral Toxicology Laboratory, Division of Neurotoxicology, National Center for Toxicological Research/FDA, Jefferson, Arkansas 72079-9502, USA. mpaule@nctr.fda.gov Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 412 EP - 417 VL - 914 SN - 0077-8923, 0077-8923 KW - Dopamine Uptake Inhibitors KW - 0 KW - Cocaine KW - I5Y540LHVR KW - Index Medicus KW - Animals KW - Drug Administration Schedule KW - Dose-Response Relationship, Drug KW - Macaca mulatta KW - Male KW - Female KW - Behavior, Animal KW - Pregnancy KW - Dopamine Uptake Inhibitors -- toxicity KW - Dopamine Uptake Inhibitors -- administration & dosage KW - Adaptation, Psychological -- physiology KW - Cocaine -- toxicity KW - Adaptation, Psychological -- drug effects KW - Cocaine -- administration & dosage KW - Uterus -- drug effects KW - Prenatal Exposure Delayed Effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70599173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=Effects+of+chronic+in+utero+exposure+to+cocaine+on+behavioral+adaptability+in+rhesus+monkey+offspring+when+examined+in+adulthood.&rft.au=Paule%2C+M+G%3BGillam%2C+M+P%3BAllen%2C+R+R%3BChelonis%2C+J+J&rft.aulast=Paule&rft.aufirst=M&rft.date=2000-09-01&rft.volume=914&rft.issue=&rft.spage=412&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-01-04 N1 - Date created - 2005-11-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Protein phosphorylation cascades associated with methamphetamine-induced glial activation. AN - 70598737; 11085325 AB - Reactive gliosis is the most prominent response to diverse forms of central nervous system (CNS) injury. The signaling events that mediate this characteristic response to neural injury are under intense investigation. Several studies have demonstrated the activation of phosphoproteins within the mitogen-activated protein kinase (MAPK) and Janus kinase (JAK) pathways following neural insult. These signaling pathways may be involved or responsible for the glial response following injury, by virtue of their ability to phosphorylate and dynamically regulate the activity of various transcription factors. This study sought to delineate, in vivo, the relative contribution of MAPK- and JAK-signaling components to reactive gliosis as measured by induction of glial-fibrillary acidic protein (GFAP), following chemical-induced neural damage. At time points (6, 24, and 48 h) following methamphetamine (METH, 10 mg/kg x 4, s.c.) administration, female C57BL/6J mice were sacrificed by focused microwave irradiation, a technique that preserves steady-state phosphorylation. Striatal (target) and nontarget (hippocampus) homogenates were assayed for METH-induced changes in markers of dopamine (DA) neuron integrity as well as differences in the levels of activated phosphoproteins. GFAP upregulation occurred as early as 6 h, reaching a threefold induction 48 h following METH exposure. Neurotoxicant-induced reductions in striatal levels of DA and tyrosine hydroxylase (TH) paralleled the temporal profile of GFAP induction. Blots of striatal homogenates, probed with phosphorylation-state specific antibodies, demonstrated significant changes in activated forms of extracellular-regulated kinase 1/2 (ERK 1/2), c-jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK), MAPK/ERK kinase (MEK1/2), 70-kDa ribosomal S6 kinase (p70 S6), cAMP responsive element binding protein (CREB), and signal transducer and activator of transcription 3 (STAT3). MAPK-related phosphoproteins exhibited an activation profile that peaked at 6 h, remained significantly increased at 24, and fell to baseline levels 48 h following neurotoxicant treatment. The ribosomal S6 kinase was enhanced over 60% for all time points examined. Immunoreactivity profiles for the transcription factors CREB and STAT3 indicated maximal increases in phosphorylation occurring at 24 h, and measuring greater than 2- or 17-fold, respectively. Specific signaling events were found to occur with a time course suggestive of their involvement in the gliotic response. The toxicant-induced activation of these growth-associated signaling cascades suggests that these pathways could be obligatory for the triggering and/or persistence of reactive gliosis and may therefore serve as potential targets for modulation of glial response to neural damage. JF - Annals of the New York Academy of Sciences AU - Hebert, M A AU - O'Callaghan, J P AD - Department of Health & Human Services, Public Health Service, Centers for Disease Control and Prevention, Morgantown, West Virginia 26505-2888, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 238 EP - 262 VL - 914 SN - 0077-8923, 0077-8923 KW - Central Nervous System Stimulants KW - 0 KW - Cyclic AMP Response Element-Binding Protein KW - Glial Fibrillary Acidic Protein KW - Proteins KW - Methamphetamine KW - 44RAL3456C KW - Tyrosine 3-Monooxygenase KW - EC 1.14.16.2 KW - Ribosomal Protein S6 Kinases, 70-kDa KW - EC 2.7.11.1 KW - JNK Mitogen-Activated Protein Kinases KW - EC 2.7.11.24 KW - Mitogen-Activated Protein Kinase 1 KW - MAP Kinase Kinase 4 KW - EC 2.7.12.2 KW - Dopamine KW - VTD58H1Z2X KW - Index Medicus KW - Animals KW - Tyrosine 3-Monooxygenase -- metabolism KW - Drug Administration Schedule KW - Glial Fibrillary Acidic Protein -- metabolism KW - Dopamine -- metabolism KW - Mice KW - Ribosomal Protein S6 Kinases, 70-kDa -- metabolism KW - Models, Biological KW - Phosphorylation -- drug effects KW - Cyclic AMP Response Element-Binding Protein -- metabolism KW - Mitogen-Activated Protein Kinase 1 -- metabolism KW - Signal Transduction -- drug effects KW - Mice, Inbred C57BL KW - MAP Kinase Kinase 4 -- metabolism KW - Time Factors KW - Female KW - JNK Mitogen-Activated Protein Kinases -- metabolism KW - Neuroglia -- metabolism KW - Methamphetamine -- administration & dosage KW - Gene Expression Regulation -- drug effects KW - Neuroglia -- drug effects KW - Central Nervous System Stimulants -- administration & dosage KW - Proteins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70598737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=Protein+phosphorylation+cascades+associated+with+methamphetamine-induced+glial+activation.&rft.au=Hebert%2C+M+A%3BO%27Callaghan%2C+J+P&rft.aulast=Hebert&rft.aufirst=M&rft.date=2000-09-01&rft.volume=914&rft.issue=&rft.spage=238&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2006-01-04 N1 - Date created - 2005-11-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - IL-4 receptor-directed cytotoxin for therapy of AIDS-associated KS tumors. AN - 70543893; 12937611 AB - AIDS-associated Kaposi's sarcoma (AIDS-KS) represents one of the most common malignancies associated with human immunodeficiency virus infection. To target effective therapeutic agents, we have discovered that AIDS-KS cells express high-affinity receptors for interleukin-4 (IL-4), a pleiotropic immune regulatory cytokine. Molecular studies have revealed that AIDS-KS cells express type II IL-4 receptors, in which IL-4 forms a productive complex with primary IL-4 binding protein (IL-4R beta, also known as IL-4R alpha) and a shared subunit between IL-4 and IL-13R systems (IL-13R alpha', also known as IL-13R alpha 1). A recombinant fusion protein composed of IL-4 and a mutated form of a powerful bacterial toxin called Pseudomonas exotoxin (PE)--the fusion protein is termed IL4(3837)-PE38KDEL or cpIL4-PE--was found to be highly and specifically cytotoxic to AIDS-KS cells in vitro. Normal human immune cells (e.g., resting T and B cells and monocytes) or endothelial cells, a possible precursor of AIDS-KS, expressed low numbers of IL-4R and showed little or no sensitivity to cpIL4-PE. Administration of cpIL4-PE in nude mice with established subcutaneously growing AIDS-KS tumors produced remarkable antitumor activity in a dose-dependent manner with the highest dose exhibiting complete responses without any visible toxicity. KS tumors produced metabolic changes including cachexia, hypoglycemia and lymphopenia, all of which were prevented by cpIL4-PE treatment. These studies indicate that cpIL4-PE is a promising experimental therapeutic agent for treatment of AIDS-KS. JF - Drug news & perspectives AU - Puri, R K AD - Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, National Institutes of Health, Bethesda, Maryland 20892, USA. Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 395 EP - 402 VL - 13 IS - 7 SN - 0214-0934, 0214-0934 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70543893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Drug+news+%26+perspectives&rft.atitle=IL-4+receptor-directed+cytotoxin+for+therapy+of+AIDS-associated+KS+tumors.&rft.au=Puri%2C+R+K&rft.aulast=Puri&rft.aufirst=R&rft.date=2000-09-01&rft.volume=13&rft.issue=7&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=Drug+news+%26+perspectives&rft.issn=02140934&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2003-11-07 N1 - Date created - 2003-08-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Restraint as a stressor in mice: against the dopaminergic neurotoxicity of D-MDMA, low body weight mitigates restraint-induced hypothermia and consequent neuroprotection. AN - 70530638; 10967304 AB - In experimental studies of stress, restraint of laboratory rodents, perceived as easy to apply and believed to be reproducible, is a commonly used manipulation. The restraint manipulation is utilized as a technique to characterize the physiological, cellular and molecular consequences of stress as well as a tool to understand the ways in which stress may interact with toxic substances. In previous work, we utilized restraint in an examination of the effect of stress on the striatal dopaminergic neurotoxicity engendered by a series of substituted amphetamines. Contrary to our expectations, and most likely due to its body temperature-reducing properties in the mouse, restraint provided total or near total protection against the neurotoxicity of these agents. During subsequent studies utilizing C57Bl6/J female mice of varying weights and ages the degree of temperature reduction and the associated ability to block (20-100%) the dopamine depletion associated with the neurotoxic amphetamine 3,4-methylendioxyamphetamine (D-MDMA, 20 mg/kg of mouse body weight, every 2 h, s.c., total of four doses) were found to vary considerably more than had been previously observed. An in-depth analysis of the role mouse weight plays in the temperature reduction induced by restraint indicates mouse weight is a primary determinant of hypothermia and subsequent neuroprotection. It suggests the induction of stress in rodents by restraint is a complex effect that may lead to unanticipated results. The restraint manipulation is not as straight-forward a procedure as is commonly believed. Our data indicate that consistent application of restraint may require an adjustment of the restrainer device to mouse body weight. JF - Brain research AU - Johnson, E A AU - Sharp, D S AU - Miller, D B AD - Chronic Stress Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health/Centers for Disease Control, 1095 Willowdale Road, Morgantown, WV 26505, USA. edj2@cdc.gov Y1 - 2000/09/01/ PY - 2000 DA - 2000 Sep 01 SP - 107 EP - 118 VL - 875 IS - 1-2 SN - 0006-8993, 0006-8993 KW - Dopamine Antagonists KW - 0 KW - Neurotoxins KW - 3,4-Methylenedioxyamphetamine KW - 4764-17-4 KW - Dopamine KW - VTD58H1Z2X KW - Index Medicus KW - Aging -- physiology KW - Animals KW - Body Temperature -- drug effects KW - Corpus Striatum -- metabolism KW - Mice, Inbred C57BL KW - Corpus Striatum -- drug effects KW - Mice KW - Brain -- metabolism KW - Rectum -- physiology KW - Female KW - Stress, Physiological -- etiology KW - Restraint, Physical KW - 3,4-Methylenedioxyamphetamine -- poisoning KW - Hypothermia -- physiopathology KW - Dopamine Antagonists -- poisoning KW - Body Weight -- physiology KW - Neurotoxins -- pharmacology KW - Dopamine -- metabolism KW - Cytoprotection -- physiology KW - Hypothermia -- etiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/70530638?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Brain+research&rft.atitle=Restraint+as+a+stressor+in+mice%3A+against+the+dopaminergic+neurotoxicity+of+D-MDMA%2C+low+body+weight+mitigates+restraint-induced+hypothermia+and+consequent+neuroprotection.&rft.au=Johnson%2C+E+A%3BSharp%2C+D+S%3BMiller%2C+D+B&rft.aulast=Johnson&rft.aufirst=E&rft.date=2000-09-01&rft.volume=875&rft.issue=1-2&rft.spage=107&rft.isbn=&rft.btitle=&rft.title=Brain+research&rft.issn=00068993&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2002-05-07 N1 - Date created - 2002-04-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - GEN T1 - Make Time To Listen, Take Time To Talk. 15+. AN - 62348313; ED450958 AB - Noting that parents and caregivers are vital to the healthy development and growth of children, this pamphlet discusses ways parents and caregivers can help children learn more about themselves and their environment in order to prevent violence. The pamphlet reminds parents to make time to listen to their children and take time to talk with them. Parents are encouraged to: (1) nurture their children; (2) model ways to control anger; (3) develop good communication with their children; (4) respect their children and teach them to respect others; (5) take interest in their child's education and development; (6) keep their child drug-free; and (7) help them develop peaceful solutions to conflict. The pamphlet also suggests ways that parents can prevent their child from becoming a bully or the victim of a bully and discusses reasons why youth join gangs. Finally, the pamphlet delineates rules for spending quality time together. (KB) Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 7 PB - Knowledge Exchange Network, P.O. Box 42490, Washington, DC 20015. KW - Relationship Quality KW - ERIC, Resources in Education (RIE) KW - Parents KW - Parent Education KW - Parent Materials KW - Parent Child Relationship KW - Child Rearing KW - Children KW - Role Models KW - Bullying KW - Adolescents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/62348313?accountid=14244 LA - English DB - ERIC N1 - Availability - Level 1 - Available online, if indexed January 1993 onward N1 - SuppNotes - Also produced by WJLA, ABC Channel 7, Washington, N1 - Last updated - 2014-03-21 ER - TY - JOUR T1 - Reflections on hexavalent chromium; health hazards of an industrial heavyweight AN - 52221372; 2001-045983 JF - Environmental Health Perspectives AU - Pellerin, Cheryl AU - Brooker, Susan M Y1 - 2000/09// PY - 2000 DA - September 2000 SP - A402 EP - A407 PB - U. S. Department of Health and Human Services, Public Health Service, Research Triangle Park, NC VL - 108 IS - 9 SN - 0091-6765, 0091-6765 KW - hazardous waste KW - concentration KW - toxic materials KW - medical geology KW - pollutants KW - effluents KW - damage KW - pollution KW - bioavailability KW - environmental effects KW - biota KW - human ecology KW - bioaccumulation KW - hexavalent chromium KW - toxicity KW - metals KW - industrial waste KW - chromium KW - public health KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52221372?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+Perspectives&rft.atitle=Reflections+on+hexavalent+chromium%3B+health+hazards+of+an+industrial+heavyweight&rft.au=Pellerin%2C+Cheryl%3BBrooker%2C+Susan+M&rft.aulast=Pellerin&rft.aufirst=Cheryl&rft.date=2000-09-01&rft.volume=108&rft.issue=9&rft.spage=A402&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+Perspectives&rft.issn=00916765&rft_id=info:doi/ L2 - http://www.jstor.org/journals/00916765.html LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2001-01-01 N1 - PubXState - NC N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - bioaccumulation; bioavailability; biota; chromium; concentration; damage; effluents; environmental effects; hazardous waste; hexavalent chromium; human ecology; industrial waste; medical geology; metals; pollutants; pollution; public health; toxic materials; toxicity ER - TY - RPRT T1 - Toxicological profile for chromium AN - 52189592; 2001-061613 JF - Toxicological profile for chromium AU - Wilbur, Sharon AU - Ingerman, Lisa AU - Citra, Mario AU - Osier, Mark AU - Wohlers, Dave Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 419 KW - water KW - soils KW - toxic materials KW - monitoring KW - medical geology KW - pollutants KW - pollution KW - bioavailability KW - bibliography KW - human ecology KW - toxicity KW - transport KW - metals KW - chemical properties KW - air KW - waste disposal KW - kinetics KW - geochemistry KW - chromium KW - public health KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52189592?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Wilbur%2C+Sharon%3BIngerman%2C+Lisa%3BCitra%2C+Mario%3BOsier%2C+Mark%3BWohlers%2C+Dave&rft.aulast=Wilbur&rft.aufirst=Sharon&rft.date=2000-09-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Toxicological+profile+for+chromium&rft.title=Toxicological+profile+for+chromium&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2001-01-01 N1 - Number of references - 1071 N1 - Availability - U. S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, Atlanta, GA, United States N1 - Document feature - illus. incl. 20 tables N1 - SuppNotes - Includes appendices N1 - Last updated - 2012-06-07 ER - TY - RPRT T1 - Toxicological profile for toluene AN - 52186707; 2001-061612 JF - Toxicological profile for toluene AU - Dorsey, Alfred AU - McClure, Peter R AU - McDonald, A Rosa AU - Singh, Mona Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 312 KW - water KW - soils KW - toxic materials KW - monitoring KW - medical geology KW - toluene KW - pollutants KW - pollution KW - bioavailability KW - environmental effects KW - bibliography KW - human ecology KW - organic compounds KW - toxicity KW - sediments KW - hydrocarbons KW - chemical properties KW - air KW - kinetics KW - geochemistry KW - aromatic hydrocarbons KW - public health KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52186707?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Dorsey%2C+Alfred%3BMcClure%2C+Peter+R%3BMcDonald%2C+A+Rosa%3BSingh%2C+Mona&rft.aulast=Dorsey&rft.aufirst=Alfred&rft.date=2000-09-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Toxicological+profile+for+toluene&rft.title=Toxicological+profile+for+toluene&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2001-01-01 N1 - Number of references - 1426 N1 - Availability - U. S. Department of Heath and Human Services, Agency for Toxic Substances and Disease Registry, Atlanta, GA, United States N1 - Document feature - illus. incl. 16 tables N1 - SuppNotes - Includes appendices N1 - Last updated - 2012-06-07 ER - TY - RPRT T1 - Draft toxicological profile for beryllium AN - 52165229; 2002-001504 JF - Draft toxicological profile for beryllium AU - Smith, Cassandra AU - Ingerman, Lisa AU - Amata, Richard Y1 - 2000/09// PY - 2000 DA - September 2000 SP - 239 KW - water KW - soils KW - concentration KW - alkaline earth metals KW - toxic materials KW - monitoring KW - degradation KW - pollutants KW - pollution KW - bioavailability KW - bibliography KW - toxicity KW - transport KW - metals KW - sediments KW - chemical properties KW - ecology KW - air KW - waste disposal KW - geochemistry KW - beryllium KW - public health KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/52165229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Smith%2C+Cassandra%3BIngerman%2C+Lisa%3BAmata%2C+Richard&rft.aulast=Smith&rft.aufirst=Cassandra&rft.date=2000-09-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Draft+toxicological+profile+for+beryllium&rft.title=Draft+toxicological+profile+for+beryllium&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2002-01-01 N1 - Number of references - 527 N1 - Availability - U. S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, Atlanta, GA, United States N1 - Document feature - illus. incl. 19 tables N1 - Last updated - 2012-06-07 ER - TY - JOUR T1 - Elevated oxidative stress in skin of B6C3F1 mice affects dermal exposure to metal working fluid AN - 18222712; 5292459 AB - Metal working fluids (MWFs) are widely used in industry for metal cutting, drilling, shaping, lubricating, and milling. Potential for dermal exposure to MWFs exists for a large number of men and women via aerosols and splashing during the machining operations. It has been reported earlier that occupational exposure to MWFs causes allergic and irritant contact dermatitis. Previously, we showed that dermal exposure of female and male B6C3F1 mice to 5% MWFs for 3 months resulted in accumulation of mast cells and elevation of histamine in the skin. Topical exposure to MWF also resulted in elevated oxidative stress in the liver of both sexes and the testes in males. The goal of this study was to evaluate the interaction between oxidative stress in the skin and topical application of MWF. Oxidative stress in skin of B6C3F1 mice of both sexes was generated by intradermal injection of the hydrogen peroxide (H sub(2)O sub(2))-producing enzyme, glucose oxidase with polyethylene glycol (GOD + PEG). In mice given GOD + PEG, topical treatment with MWF (200 mu l, 30%, for 1, 3, or 7 days) resulted in a mixed inflammatory cell response, accumulation of peroxidative products, and reduction of GSH content in the skin. Such changes were not observed with MWF treatment alone. These data indicate that oxidative stress can enhance dermal inflammation caused by occupational exposure to MWF. JF - Toxicology and Industrial Health AU - Shvedova, A A AU - Kisin, E AU - Kisin, J AU - Castranova, V AU - Kommineni, C AD - Health Effects Laboratory Division, Pathology and Physiology Research Branch, NIOSH m/s 2015, 1095 Willowdale Road, Morgantown, WV 26505, USA, ats1@cdc.gov Y1 - 2000/09// PY - 2000 DA - Sep 2000 SP - 267 EP - 276 VL - 16 IS - 7-8 SN - 0748-2337, 0748-2337 KW - mice KW - metal working fluids KW - Toxicology Abstracts KW - Glucose oxidase KW - Skin KW - Oxidative stress KW - Hydrogen peroxide KW - Polyethylene glycol KW - Occupational exposure KW - Inflammation KW - X 24151:Acute exposure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/18222712?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Industrial+Health&rft.atitle=Elevated+oxidative+stress+in+skin+of+B6C3F1+mice+affects+dermal+exposure+to+metal+working+fluid&rft.au=Shvedova%2C+A+A%3BKisin%2C+E%3BKisin%2C+J%3BCastranova%2C+V%3BKommineni%2C+C&rft.aulast=Shvedova&rft.aufirst=A&rft.date=2000-09-01&rft.volume=16&rft.issue=7-8&rft.spage=267&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Industrial+Health&rft.issn=07482337&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Polyethylene glycol; Occupational exposure; Hydrogen peroxide; Glucose oxidase; Skin; Oxidative stress; Inflammation ER - TY - JOUR T1 - Effects of metal working fluids on B6C3F1 mouse skin AN - 17861640; 5109547 AB - Over 10 million workers in the United States are exposed to metal working fluids (MWFs) through dermal contact and/or inhalation of aerosolized fluids. The objective of this study was to elucidate the response of skin to dermal exposure to MWFs. Four- to six-week-old B6C3F1 mice of both sexes were divided into eight groups (n=5/group) and exposed to 200 mu l of 0%, 5% (pH 7 and 9.7) and 100% (pH 10.4), unused MWFs/H sub(2)O by topical application to the unshaven back (cervical to sacral region), twice a week for 6 weeks. Skin-mast cell number in females of most treated groups and of two male groups (100% and 5%, pH 7) were significantly higher than the control groups. Eventhough both males and females (treated with 100% MWF/H sub(2)O) showed an increase in the skin-histamine levels (38% and 41%, respectively), this increase was significant in females only (ANOVA, P less than or equal to 0.05). Dermal exposure to 100% MWFs increased liver weight significantly in both sexes. Ulcers and associated inflammation were seen in the skin of mice treated with 100% unused MWFs and sacrificed at 6 weeks, but not in the recovery groups. Hypertrophy of the sebaceous gland epithelium is present in all mice treated for 6 weeks and sacrificed immediately. However, only the mice treated with 100% MWF retained the hypertrophy of this epithelium after a 6-week recovery period. In conclusion, dermal exposure to unused semi-synthetic MWF penetrates the normal skin, induces mast cell accumulation in the skin, produces hypertrophy of the sebaceous glands, and may affect females more than males. JF - Toxicology and Industrial Health AU - Al-Humadi, N H AU - Battelli, L AU - Willard, P A AU - Schwegler-Berry, D AU - Castranova, V AU - Kommineni, C AD - HELD, NIOSH 1095 Willowdale Road, Morgantown, WV 26505, USA, cdk2@cdc.gov Y1 - 2000/09// PY - 2000 DA - Sep 2000 SP - 203 EP - 210 VL - 16 IS - 6 SN - 0748-2337, 0748-2337 KW - mice KW - Toxicology Abstracts KW - Hypertrophy KW - Skin KW - Epithelium KW - Metal-working fluids KW - Sebaceous gland KW - Occupational exposure KW - X 24151:Acute exposure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17861640?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Industrial+Health&rft.atitle=Effects+of+metal+working+fluids+on+B6C3F1+mouse+skin&rft.au=Al-Humadi%2C+N+H%3BBattelli%2C+L%3BWillard%2C+P+A%3BSchwegler-Berry%2C+D%3BCastranova%2C+V%3BKommineni%2C+C&rft.aulast=Al-Humadi&rft.aufirst=N&rft.date=2000-09-01&rft.volume=16&rft.issue=6&rft.spage=203&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Industrial+Health&rft.issn=07482337&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2006-11-01 N1 - Last updated - 2011-12-13 N1 - SubjectsTermNotLitGenreText - Skin; Metal-working fluids; Occupational exposure; Epithelium; Hypertrophy; Sebaceous gland ER - TY - JOUR T1 - Structural parameters and floristic composition of one hectare of terra firme dense forest in the Uatuma River Valley, Amazonia, Brazil TT - Composicao floristica e parametros estruturais de um hectare de floresta densa de terra firme no Rio Uatuma, Amazonia, Brasil AN - 17803034; 4849009 AB - An area of terra firme dense forest in the Uatuma River basin, county of Sao Sebastiao, Amazonas, Brazil was surveyed. The floristic composition, richness of species, and structural parameters of the vegetation were studied. A survey of one hectare was carried out by using a transect of 10 x 1000 m, divided in 20 plots of 10 x 50 m, where every individual with a diameter at breast height (DBH) greater than or equal to 10 cm was measured, including trees, lianas and palms. The understory stratum was studied by using small plots of 2 x 2 m, according to the size category criterion. Structural parameters were assessed through the Importance Value Index (IVI) of the species, the number of individuals per class of diameter, and the biological spectrum of the understory stratum. A total of 741 individuals (with DBH greater than or equal to 10 cm) were recorded, distributed in 46 families, 118 genera and 145 species. Families with the greatest number of species were Leguminosae sensu lato (33), Myrtaceae (8) and Lauraceae (7), representing 33% of the total recorded individuals. Protium apiculatum and Eschweilera coriacea were the species with higher IVI (22.4 and 17.6 respectively), representing 15% of the total IVI. These two species presented more uniform distributions and greatest number of individuals in the area. The understory stratum was composed of a high proportion (28.7%) of individuals, corresponding to 25.4% of total species, which have their whole life circle in this stratum. Therefore, these species should not be included as part of forest regeneration, as practiced by many projects of forest management. JF - Acta Amazonica AU - Do Amaral, IL AU - Matos, FDA AU - Lima, J AD - Instituto Nacional de Pesquisas da Amazonia (INPA), Coordenacao de Pesquisas em Botanica (CPBO), Av. Andre Araujo, 2936, Petropolis, CEP 69.083-000, Manaus, AM. Brasil, iamaral@inpa.gov.br Y1 - 2000/09// PY - 2000 DA - Sep 2000 SP - 377 EP - 392 VL - 30 IS - 3 SN - 0044-5967, 0044-5967 KW - Brazil KW - Ecology Abstracts KW - Vegetation patterns KW - Tropical environment KW - Forests KW - D 04126:Tropical forests UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/17803034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+Amazonica&rft.atitle=Structural+parameters+and+floristic+comp